diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..884813dd16650df34831385d765007d0befa28c2 --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]"} \ No newline at end of file diff --git a/interpro_active_site/advanced/plot_0.png b/interpro_active_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2e39919b6ad75f24524d9fb54c5e66972f51fbb1 --- /dev/null +++ b/interpro_active_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a78f76afacee9e252964bee5ae50956b2059e2b988790cf4f4a38dfd795c8444 +size 201839 diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..884813dd16650df34831385d765007d0befa28c2 --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f0cd01ca92e90a49e8610bf480f4af229575b9a4 --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8b2276b367558bd98d5582d0e2b6e8589b4322d3d5c718966050ccdd61aae3ef +size 155105 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..96b8996919deb7e12cf236fab12bfcac9806681e --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4547d9923410abf923b0672a98d08048e586c4b1b2b0fb4424f960c538de8206 +size 79596 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..95227c795e1968f12be2c59cf9ade94884cf08dd --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Serine/threonine-protein kinase, active site [IPR008271] 33 59 3.575388513998969 0.0003497081781946 14.96359223300971 48.092233009708735 -0.2514056606840174 0.5845564538757478 7.386430402173519 10.05983255009733 0.9463339478376924 0.3271131887386243 0.6634464974625899 0.3764355050375718 0.6634020320082967 0.4591779800392646 +Ubiquitin-conjugating enzyme, active site [IPR023313] 4 5 2.153950234147777 0.0312440748698281 2.941747572815534 5.601941747572815 -0.2752660098412252 0.4763282738496994 1.5568529541181904 0.8795387783526502 0.970372159321031 0.2983809723869815 0.0967463289884207 0.1880666528119386 0.4147125777305785 0.088385561156941 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1c55e647c1252a1c63a8b6871a4ae9e9db0a06fc --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 54, + "title": "Average number of proteins per term", + "value": 2.962962962962963 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3fb588b3751899bbb0c1d9c1ea5a5757e6bcc4a2 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fd492f90d9c16bd8b5dac7b1bea90b857cceb1dd --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine/threonine-protein kinase, active site [IPR008271] 0.4937430841958833 3.575388513998969 0.0003497081781946 0.0187102924187359 0.018884241622513 59 P49761,Q00535,P33981,P53350,Q8TD19,P52564,Q99570,Q96KB5,O75116,Q16512,O96017,O15111,P36507,P11802,O43318,Q96SB4,P19784,P78362,O43683,Q13555,Q13464,O14965,P31751,P28482,Q16513,Q14012,Q13153,P45985,Q99986,Q9NYV4,Q9H2G2,Q00534,P17612 33 +Peptidase family C14A, His active site [IPR016129] 0.8473715651134954 2.198746487402937 0.0278959534446994 0.7829856002486778 0.1687180042970721 4 P55212,P42574,Q14790 3 +Peptidase family C14A, cysteine active site [IPR033139] 0.8473715651134954 2.198746487402937 0.0278959534446994 0.7829856002486778 0.1687180042970721 4 P55212,P42574,Q14790 3 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.7965342097400587 2.153950234147777 0.0312440748698281 0.8198741366788258 0.1687180042970721 5 P68036,P49427,P61086,Q16763 4 +Protein-tyrosine phosphatase, active site [IPR016130] 0.5757757406545003 1.4147196411491854 0.157150713263813 0.9999021646335806 0.3815795494487377 7 Q8NCE2,O60942,Q06124 3 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.7503732457449978 1.206534486279664 0.2276114701971925 0.9999991227284392 0.4727315150249383 3 P22314,Q9UBT2 2 +Adenosine/AMP deaminase active site [IPR006650] 0.9373134328358216 1.0351854276152583 0.300582322890798 0.9999999958716488 0.5410481812034363 2 P00813 1 +Nucleoside diphosphate kinase, active site [IPR023005] 0.8023880597014958 0.5989861469133185 0.5491821225229754 1.0 0.6896705724707133 2 P15531 1 +L-lactate dehydrogenase, active site [IPR018177] 0.6322388059701547 0.1959549435302278 0.8446454320786476 1.0 0.9065788327772358 2 P00338 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..495ff452fb620f452c699b34fb2ac0d8e7770b8b --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP6", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "OXSM", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ADA", "AKT2", "AURKA", "BUB1", "CAMK1", "CAMK2G", "CASP3", "CASP6", "CASP8", "CDC34", "CDK12", "CDK4", "CDK5", "CDK6", "CHEK2", "CHUK", "CLK3", "CSNK2A2", "LDHA", "MAP2K2", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MTMR14", "NEK9", "NME1", "PAK1", "PBK", "PIK3R4", "PKN1", "PKN2", "PLK1", "PRKACA", "PTPN11", "RNGTT", "ROCK1", "ROCK2", "SLK", "SRPK1", "SRPK2", "TTK", "UBA1", "UBA2", "UBE2K", "UBE2L3", "UBE2S", "VRK1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..465c03bba181ece1b3cfc758ab37913f62157507 --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein kinase, ATP binding site [IPR017441]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f1261e42d4473923101f59384f91ecf8e84c0dec --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d929890b4d697e5a27cb64f09dd036ff18b463e9a1c135e18f930fd4e27dd6f +size 196426 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a187f3c48e8abd4103decb2e8ec6243ef9e1c365 --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "Beta tubulin, autoregulation binding site [IPR013838]", "2": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..29d43ed5c7bca39aa61b72f345f7a76655e77eb5 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f011886c794de03b15aaec220e6087cf8832d45052481ce0f2dff1063b6e664b +size 154128 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..93b50efd3a94413ebb4fd1d335a4164cd8bc68df --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6be3e294954f6c89db0cf82cb64cad1a3f6f23b2f6c7212ec9f626712cb8fdf2 +size 137237 diff --git a/interpro_binding_site/basic/plot_2.png b/interpro_binding_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..f45f9ac5e2699c95a356b96afc86a943997e7d58 --- /dev/null +++ b/interpro_binding_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2538996f4332e596d114d818fb7067245d643e293571d0f6987a48c653b79cf +size 150708 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8f88f57b5a28653dd366fd898d3c821ff9fb4d6b --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c11bb2860d90f0dd36c79de9039fa9b1aa011a3416981a66dc0fe586c2dfd73b +size 76717 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b70e227ceed38ca8adb9686b26fdcc56d509eaba --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Protein kinase, ATP binding site [IPR017441] 32 56 3.587005924520518 0.0003344967265612 13.985436893203884 45.86407766990291 -0.192126652758297 0.6147860592683837 6.814446501353132 9.80766348241306 0.8651595242963739 0.3198537516496491 0.7148624146480367 0.4645465512342815 0.7766024211207183 0.5423224058995517 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..92d05df8db92e8f94b5d6fb7796e7e6d1452aa47 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 5.032258064516129 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4b4104db16ba8e5c460285eb06058d033a3f6cc4 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..37ea655e1ffacfb4555e95dc94d21b186b9d0026 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein kinase, ATP binding site [IPR017441] 0.5072813620200225 3.587005924520518 0.0003344967265612 0.0103175384129876 0.0103693985233994 56 P49761,Q00535,P33981,P53350,P41240,Q16539,O75116,Q16512,O15111,P36507,P11802,O43318,Q96SB4,P19784,P78362,O43683,Q13555,Q13464,Q13043,O14965,P31751,P28482,Q16513,Q14012,Q13153,P45985,Q99986,Q9NYV4,Q9UHD2,Q9H2G2,Q00534,P17612 32 +Beta tubulin, autoregulation binding site [IPR013838] 0.6511003442627634 1.785667923297136 0.0741530419824463 0.9082269166035885 0.2554160334950928 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Peptidase M16, zinc-binding site [IPR001431] 0.5138414720916775 0.8744827537102834 0.3818554082673786 0.9999996659647572 0.6963245680169846 5 O43847 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.3053593962361765 0.379500564438764 0.704316185210627 1.0 0.8806515928505666 35 Q9H4M9,P19174,P17655,Q14257,Q96D71,Q96AY3,Q15293 7 +PPM-type phosphatase, divalent cation binding [IPR000222] 0.4034725683324822 0.3401112568082449 0.7337727448671485 1.0 0.8806515928505666 4 O15355 1 +Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.7023880597014961 0.3336932901216952 0.7386110133585397 1.0 0.8806515928505666 2 P50579 1 +IQ motif, EF-hand binding site [IPR000048] 0.2306367383675482 0.1345681701356472 0.8929533092011304 1.0 0.968641690432158 11 Q15386 1 +Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578] 0.5746268656716489 0.1178977473609794 0.9061486781462122 1.0 0.968641690432158 2 Q9Y617 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..998d041f77ead60eb669965f38335e1b2c2bb9ea --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQSEC1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PPM1L", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["AKT2", "AURKA", "BUB1", "CAMK1", "CAMK2G", "CAPN2", "CDK12", "CDK4", "CDK5", "CDK6", "CHUK", "CLK3", "CSK", "CSNK2A2", "EHD1", "FKBP10", "MAP2K2", "MAP2K4", "MAP3K7", "MAPK1", "MAPK14", "METAP2", "NRDC", "PAK1", "PKN1", "PKN2", "PLCG1", "PLK1", "PPM1G", "PRKACA", "PSAT1", "RCN1", "RCN2", "REPS1", "ROCK1", "ROCK2", "SLK", "SRPK1", "SRPK2", "STK4", "TBK1", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "VRK1"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f62ed46b50b7139d518f42279d60ec6f71ef70da --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "2": "Tubulin, conserved site [IPR017975]", "3": "Chaperonin TCP-1, conserved site [IPR002194]", "4": "Ubiquitin specific protease, conserved site [IPR018200]", "5": "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "6": "Kinesin motor domain, conserved site [IPR019821]", "7": "Zinc finger, RING-type, conserved site [IPR017907]", "8": "Actinin-type actin-binding domain, conserved site [IPR001589]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 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+version https://git-lfs.github.com/spec/v1 +oid sha256:21e70278c9d5a13bb3f7a3ffacd2b6c5c7ad461cf10b8b70e79f5253309a64ee +size 85146 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..409c6f551edf04c113fbd42aae50c25066e5bf1f --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 279, + "title": "Average number of proteins per term", + "value": 2.824372759856631 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4fdc8406cb4941fc53995c2cca8ab750171ba0be --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bba002bb3bba85defde5c0b48d940b9580b5e7dd --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,43 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome beta-type subunit, conserved site [IPR016050] 0.6465547742034614 1.8952492006595416 0.0580593947101548 0.9999999434331782 0.4190762032145759 8 P49720,P28074,P20618,P28070,P49721 5 +DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.5764101106317628 1.8247061883945856 0.0680453789095987 0.9999999971083898 0.4190762032145759 16 Q7Z478,Q86WJ1,Q6P158,Q8IX18,P18074,O60231 6 +Tubulin, conserved site [IPR017975] 0.6511003442627634 1.785667923297136 0.0741530419824463 0.999999999538217 0.4401850790021813 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Chaperonin TCP-1, conserved site [IPR002194] 0.5730108939582609 1.520044051847889 0.1284999044896051 1.0 0.5248659626258442 8 P49368,Q99832,P50991,P40227,P17987,P48643 6 +Ubiquitin specific protease, conserved site [IPR018200] 0.5211742935029549 1.500179003068911 0.1335680406682255 1.0 0.5248659626258442 16 Q86UV5,Q9UPT9,O94966,Q96K76,Q93008,P45974,P51784,Q96RU2,P40818 9 +Cullin, conserved site [IPR016157] 0.6064008586020968 1.4517029119599465 0.1465842292949273 1.0 0.5526621618011449 6 Q13617,Q13618,Q13619,Q93034 4 +Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.7897236534050314 1.358815819266995 0.1742049592165053 1.0 0.5927217514805487 3 Q14155 1 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.7832833013467517 1.3338662554742216 0.1822476923515132 1.0 0.612615736940629 3 Q9Y2T2 1 +Phosphofructokinase, conserved site [IPR015912] 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.6233164192561534 3 P17858,P08237 2 +IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.756345177664961 1.2296062767997211 0.2188445784100006 1.0 0.6623432469712385 3 Q9P2T1,P20839 2 +Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.4713572044460673 1.2050984170177577 0.2281653108470873 1.0 0.6674296489888435 14 Q9P2J5,P26640,P07814,P47897,P41252,P23381,P54136 7 +Mrp, conserved site [IPR000808] 0.7301034508729122 1.128422032583512 0.259141727229212 1.0 0.6951975182399053 3 Q9Y5Y2 1 +14-3-3 protein, conserved site [IPR023409] 0.4968568382531855 1.0227204740233795 0.3064400281565951 1.0 0.7682280755779253 7 P31946,P27348 2 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.6884986990031459 0.9696740553549288 0.3322089866479358 1.0 0.792301349644149 3 P09429 1 +Kinesin motor domain, conserved site [IPR019821] 0.4210467622236042 0.9153255041483546 0.3600207739005858 1.0 0.8064140481181525 14 Q99661,Q15058,P33176,Q96Q89,P52732,O60333 6 +Oxysterol-binding protein, conserved site [IPR018494] 0.4613954580566096 0.7660459873250592 0.4436489395376237 1.0 0.8279050390757784 6 P22059,Q96SU4,Q9BZF3 3 +Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.6290758967998564 0.7499379847854124 0.4532920558272821 1.0 0.8320294972092876 3 P28482 1 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.4337644315296222 0.7193945943615955 0.4718978265646212 1.0 0.8530889607213245 7 Q13535 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.8173134328358231 0.6438836476654733 0.5196508863232758 1.0 0.8963986382922134 2 O00429 1 +Ubiquitin conserved site [IPR019954] 0.5878653535772396 0.6058854342460944 0.5445908323679414 1.0 0.9125730961268518 3 P46379 1 +Ras GTPase-activating protein, conserved site [IPR023152] 0.586443714541647 0.6010827033852744 0.5477849031519446 1.0 0.9125730961268518 3 P46940,P21359 2 +Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.8020895522388085 0.5980997164773257 0.5497733994361262 1.0 0.9125730961268518 2 Q9UBT2 1 +Zinc finger, RING-type, conserved site [IPR017907] 0.3631587784192616 0.5881392510370853 0.5564388290399722 1.0 0.9125730961268518 19 O15344,Q14258,Q5VTR2,O95376,P19474,Q14527,Q9UPN9,P22681 8 +Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.7982089552238816 0.5866189161788037 0.5574596754556114 1.0 0.9125730961268518 2 P09972 1 +Helix-hairpin-helix motif, class 2 [IPR008918] 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.9142743953786896 2 Q9UQ84 1 +XPG conserved site [IPR019974] 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.9142743953786896 2 Q9UQ84 1 +Purine phosphorylase, family 2, conserved site [IPR018099] 0.7800000000000056 0.5338587902352129 0.593439235364994 1.0 0.9407360606070077 2 Q13126 1 +Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.7364179104477637 0.4160177804228269 0.6773969924784313 1.0 0.9807269104065692 2 P06730 1 +Profilin conserved site [IPR027310] 0.734925373134331 0.412216966164904 0.6801804026918581 1.0 0.9807269104065692 2 P35080 1 +Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.7179104477612002 0.3700948594479744 0.7113118121835174 1.0 0.9807269104065692 2 Q00796 1 +Rel homology domain, conserved site [IPR030492] 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.9807269104065692 2 Q00653 1 +Actin/actin-like conserved site [IPR020902] 0.4911534125165862 0.3155187983944882 0.7523677803812925 1.0 0.9825332543775562 3 P61163 1 +GTP1/OBG, conserved site [IPR006074] 0.6725373134328403 0.2695233565473214 0.7875269710646449 1.0 0.9964110071300216 2 Q9Y295 1 +tRNA-dihydrouridine synthase, conserved site [IPR018517] 0.6382089552238859 0.2058732267266906 0.8368899394344851 1.0 0.9964110071300216 2 Q6P1R4 1 +DnaJ domain, conserved site [IPR018253] 0.2424845897724784 0.1588848981236496 0.8737595590988045 1.0 1.0 11 O60884,P31689 2 +Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.4122939343036108 0.1533303443970814 0.8781377722335437 1.0 1.0 3 O95394 1 +Actinin-type actin-binding domain, conserved site [IPR001589] 0.2297783103654937 0.1226259088023625 0.9024033370208672 1.0 1.0 14 P46939,O15020,Q9UPN3,Q15149,Q03001,Q14651,O75369,Q14315,O43707,P21333,P12814,Q01082,P13797 13 +Tr-type G domain, conserved site [IPR031157] 0.2671114121118708 0.112611364243914 0.9103386750012306 1.0 1.0 6 Q05639 1 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.3159151985667253 0.0592836997672978 0.9527261439796642 1.0 1.0 3 O00469,O60568 2 +Polyprenyl synthetase, conserved site [IPR033749] 0.4594029850746369 0.0447490433138045 0.964307341913662 1.0 1.0 2 O95749 1 +Homeobox, conserved site [IPR017970] 0.3916417910447846 0.0335830696411578 0.9732096231221844 1.0 1.0 2 P31260 1 +Polyamine biosynthesis domain, conserved site [IPR030373] 0.3680597014925459 0.0321362998207217 0.9743633552799372 1.0 1.0 2 P19623 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bb11ffbc8bb83bac46f0d5aba264ce647e457ecf --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Carbonic anhydrase, alpha-class, conserved site [IPR018338]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARHGEF7", "ARIH2", "ARRB1", "ARSA", "ATAD1", "ATAD2", "ATAD2B", "ATM", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CA8", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS1L", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPR2", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXA10", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "IQGAP1", "IQGAP2", "ISCA2", "IVD", "KATNA1", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LIG4", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFM", "NES", "NF1", "NFKB2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NSUN6", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RNF169", "RNF2", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SFN", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE4", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0cab61169d3760bc1f3ecd73139d3d596cff75ce5d950d21c3817c71545b334d +size 234568 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..23922936095dd0bb9738c5f1657478e381b7e8bb --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Protein kinase domain [IPR000719] 39 71 3.1415512096227483 0.0016805541696225 18.101941747572816 59.74514563106796 -0.2447486486560373 0.6172415587925009 8.775755222472991 12.77818988078034 0.8704293873391331 0.3201152559326328 0.7907510506841838 0.6116048181299928 0.9069399502726392 0.8285583472757916 +HECT domain [IPR000569] 5 10 2.7710477128692377 0.0055876238499039 3.5364077669902914 8.95631067961165 -0.082655155531572 0.5172769027958292 2.244980314039549 2.0498718834184824 0.9922663464789628 0.3114818745947644 1.0 0.2182850433665622 0.1283849415189241 0.0074494564855197 +Glutathione S-transferase, C-terminal-like [IPR010987] 6 12 2.3313151021291234 0.0197367504662859 3.949029126213592 11.37621359223301 -0.0908035435769439 0.5323098181486043 2.6346872162188446 1.2313530457632356 0.9588413776865506 0.2992576122582335 1.0 0.1405588989726414 0.3225700131084155 0.0062633876942655 +Ubiquitin-conjugating enzyme E2 [IPR000608] 7 10 2.3254681595411872 0.020046940561897 3.95873786407767 8.441747572815533 -0.3623537293483046 0.4974951403700478 2.0386427902971107 1.2043629643395506 0.9375345291131654 0.3025573177165397 0.1416218084112404 0.2685126379615966 0.5524281428970466 0.0203628052401783 +Post-SET domain [IPR003616] 0 5 2.185475610958968 0.0288539922822992 1.6262135922330097 4.279126213592233 0.0613915158923178 0.4259392793014407 1.34781096633775 1.5894834031610705 1.2346341950543411 0.3069964316941106 0.0670021260054199 0.1323778037089543 0.3058660732099017 0.5262254411875915 +SET domain [IPR001214] 1 8 2.1817473482458705 0.0291281843742812 2.3762135922330097 7.203883495145631 0.2385276779443848 0.4071855892228946 1.7492625999828462 2.5849047354362957 1.1957336270516616 0.3024983972109138 0.1690349275366953 0.0543070281832774 0.2497167706923579 0.5850817530243546 +Phosphoribosyltransferase domain [IPR000836] 5 6 2.1543065788634093 0.0312161372926347 3.851941747572816 6.237864077669903 -0.48286962932896 0.4630313109558172 1.7320286989776996 0.7515183988800389 0.9869863341926838 0.3197491703415464 1.0 1.0 0.2159896916124382 0.0105668672564949 +Peptidase C14, p20 domain [IPR001309] 3 5 2.1210797942136623 0.0339150880240943 1.0429042904290429 2.254125412541254 -0.1822739771754456 0.4061856906844451 0.8796230895210494 1.190490848145931 1.5263000234628414 0.3357787389369007 1.0 0.0729118409275157 0.0146338936924203 0.0003286021100258 +Ubiquitin-associated domain [IPR015940] 9 17 2.118001732062495 0.03417492099605 4.757281553398058 13.609223300970871 0.1518609635645758 0.6189618326330407 2.6965134605741876 2.7315510687883564 0.8294496783626069 0.3065476877023595 0.1690349275366953 0.3155444220122531 0.0706809399762649 0.0119603409362114 +Importin-beta, N-terminal domain [IPR001494] 10 13 2.1005102919406164 0.0356839762216867 6.385922330097087 13.28883495145631 0.1695856896111973 0.5104356360219653 3.297409379395681 0.8134617396566306 1.1027535719761996 0.3475482514742156 1.0 0.0108829135912838 0.0072626368836444 0.0078812527225172 +SH2 domain [IPR000980] 6 10 2.0577726085014185 0.0396119666458449 4.237864077669903 10.385922330097088 -0.412666598532829 0.4936495124083884 2.3651439950767164 2.0298969015348023 0.8863115778683005 0.2948921309362726 1.0 1.0 1.0 0.1272114080331624 +Importin-alpha, importin-beta-binding domain [IPR002652] 0 5 2.0552721386820574 0.0398527268110915 1.900485436893204 4.179611650485437 -0.0879924391494337 0.5961199277101574 1.2177090368111774 0.6874547431954602 0.834731806091852 0.3002594480637005 1.0 1.0 0.1768749528600843 0.3285208438252537 +Domain of unknown function DUF1605 [IPR011709] 5 13 1.9876337896602816 0.0468522064416323 6.106796116504855 12.0752427184466 -0.2985806998135454 0.555257710597532 3.0913679422786324 1.3957872432668228 0.8357204766502752 0.308662288818408 1.0 0.1405588989726414 0.0553069748090555 0.0007388687073799 +Helicase-associated domain [IPR007502] 5 13 1.9876337896602816 0.0468522064416323 6.106796116504855 12.0752427184466 -0.2985806998135454 0.555257710597532 3.0913679422786324 1.3957872432668228 0.8357204766502752 0.308662288818408 1.0 0.1405588989726414 0.0553069748090555 0.0007388687073799 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eeb01dfc65b2a43c7f4155a09521fccceb44e762 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 2723, + "title": "Average number of proteins per term", + "value": 2.2291590157914065 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..09f28e14c25eeb28148dd8191e7889925dfa0c20 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..414c52f6265fa7c62be391ee276dce0f3b39bda0 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,333 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein kinase domain [IPR000719] 0.4719807078849586 3.1415512096227483 0.0016805541696225 0.989745088839583 0.3422552349755762 71 P49761,Q00535,P33981,P53350,P41240,Q8TD19,P52564,Q16539,Q99570,Q96KB5,O75116,Q13546,Q16512,O96017,O15111,P36507,P11802,O43318,Q96SB4,P19784,P78362,Q8IV63,O43683,Q13555,Q13464,Q13043,O14965,P31751,P28482,Q16513,Q14012,Q13153,P45985,Q99986,Q9NYV4,Q9UHD2,Q9H2G2,Q00534,P17612 39 +HECT domain [IPR000569] 0.7575491789353765 2.7710477128692377 0.0055876238499039 0.9999997636062248 0.3422552349755762 10 Q9UII4,Q9ULT8,O95071,Q05086,Q15386 5 +E3 ligase, CCCH-type zinc finger [IPR041367] 0.8871300226448375 2.3638075544001724 0.0180882059320901 1.0 0.3422552349755762 4 Q9UPT8 1 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.6709245307392193 2.3313151021291234 0.0197367504662859 1.0 0.3422552349755762 12 O00299,P26640,Q8NEC7,P78417,P28161,P26641 6 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.6710355545284695 2.3254681595411872 0.020046940561897 1.0 0.3422552349755762 10 Q9C0C9,Q9NR09,P68036,P49427,P61086,Q16763,Q7Z7E8 7 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.8762540444891773 2.3189411316898387 0.0203982284924997 1.0 0.3422552349755762 4 P48147,Q86TI2 2 +Peptidase C14A, caspase catalytic domain [IPR015917] 0.8473715651134954 2.198746487402937 0.0278959534446994 1.0 0.3422552349755762 4 P55212,P42574,Q14790 3 +Peptidase C14, caspase non-catalytic subunit p10 [IPR002138] 0.8473715651134954 2.198746487402937 0.0278959534446994 1.0 0.3422552349755762 4 P55212,P42574,Q14790 3 +SET domain [IPR001214] 0.7043075574905576 2.1817473482458705 0.0291281843742812 1.0 0.3422552349755762 8 Q03164 1 +Phosphoribosyltransferase domain [IPR000836] 0.7573221757322229 2.1543065788634093 0.0312161372926347 1.0 0.3422552349755762 6 P11172,Q06203,P00492,P07741,O60256 5 +Peptidase C14, p20 domain [IPR001309] 0.7889972789729206 2.1210797942136623 0.0339150880240943 1.0 0.3422552349755762 5 P55212,P42574,Q14790 3 +Ubiquitin-associated domain [IPR015940] 0.6257499200783532 2.118001732062495 0.03417492099605 1.0 0.3422552349755762 17 Q6P158,Q7Z6Z7,Q04323,P61086,Q13501,Q96S82,Q14157,Q9Y5A7,P22681 9 +Importin-beta, N-terminal domain [IPR001494] 0.6277710818592424 2.1005102919406164 0.0356839762216867 1.0 0.3422552349755762 13 O00410,Q92973,O15397,Q8TEX9,O95373,O14980,Q9UIA9,P55060,Q96P70,Q9HAV4 10 +SH2 domain [IPR000980] 0.6210735292786546 2.0577726085014185 0.0396119666458449 1.0 0.3422552349755762 10 O15357,P19174,P41240,P46109,Q06124,P40763 6 +Domain of unknown function DUF1605 [IPR011709] 0.6074985358678886 1.9876337896602816 0.0468522064416323 1.0 0.345336980173487 13 Q7Z478,Q6P158,Q8IX18,O60231,Q9H6S0 5 +Helicase-associated domain [IPR007502] 0.6074985358678886 1.9876337896602816 0.0468522064416323 1.0 0.345336980173487 13 Q7Z478,Q6P158,Q8IX18,O60231,Q9H6S0 5 +Zinc finger, CXXC-type [IPR002857] 0.7924810774661043 1.9662452065594056 0.0492702928117034 1.0 0.3484741288761158 4 Q03164 1 +Mu homology domain [IPR028565] 0.7907093109138746 1.9586550839521149 0.0501531939464507 1.0 0.3484741288761158 4 Q9Y2T2,P48444 2 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7495328962056594 1.9471976434165463 0.0515110441208395 1.0 0.3484741288761158 5 P09960,P55786 2 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7495328962056594 1.9471976434165463 0.0515110441208395 1.0 0.3484741288761158 5 P09960,P55786 2 +THIF-type NAD/FAD binding fold [IPR000594] 0.682511210762338 1.937479820025199 0.0526867178213308 1.0 0.3484741288761158 7 Q8TBC4,Q9UBT2,A0AVT1,P22314,Q13564,O95352 6 +Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.6770740026826286 1.911346516776024 0.0559600649129063 1.0 0.3519650028429043 7 P60900,O14818,P28066,P25786,P25787 5 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.9239063275631968 1.8746614082691997 0.0608393192473091 1.0 0.356766013428327 3 P28340 1 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.9239063275631968 1.8746614082691997 0.0608393192473091 1.0 0.356766013428327 3 P28340 1 +Zinc finger, UBR-type [IPR003126] 0.7706093189964123 1.8721948752732211 0.0611796478333996 1.0 0.356766013428327 4 O95071,Q8N806,Q8IWV7 3 +TOG domain [IPR034085] 0.6951583980872702 1.8698907105275309 0.0614989960698251 1.0 0.356766013428327 6 Q14008,Q8TEX9,Q7Z460,Q86Y56,Q92616 5 +AGC-kinase, C-terminal [IPR000961] 0.5861541778231574 1.865442511388196 0.0621194032590703 1.0 0.356766013428327 11 O75116,P31751 2 +Glutathione S-transferase, N-terminal [IPR004045] 0.6645902532310519 1.8511110910124804 0.0641535728296927 1.0 0.3578019507855611 7 P78417,P28161,P26641 3 +Cullin, N-terminal [IPR001373] 0.6350569557604433 1.8372823485970011 0.0661682243107175 1.0 0.358202932004143 8 Q13619,Q13618,Q93034,Q13617,Q14999 5 +Dual specificity phosphatase, catalytic domain [IPR000340] 0.7553763440860123 1.806254258770128 0.070878633119737 1.0 0.362779459876785 4 O60942,Q9UNI6,Q99956 3 +Dual specificity protein phosphatase domain [IPR020422] 0.7553763440860123 1.806254258770128 0.070878633119737 1.0 0.362779459876785 4 O60942,Q9UNI6,Q99956 3 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3693185761033924 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3693185761033924 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.5674045015679084 1.762346856986339 0.0780107116068831 1.0 0.3728726173849102 10 O94973,P53618,O43747,Q9Y678,O00203,Q10567,Q9UBF2,O14617 8 +Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.8942968050164174 1.7619678511773589 0.078074729391012 1.0 0.3728726173849102 3 Q9Y6D5,Q7Z3U7 2 +Methyltransferase domain [IPR025714] 0.8940532052888337 1.7610372183417464 0.0782321038345394 1.0 0.3728726173849102 3 Q8NEC7 1 +Cyclin, N-terminal [IPR006671] 0.743803033158579 1.7559300108686042 0.0791003598856421 1.0 0.3728726173849102 4 P20248,O95067 2 +Cyclin, C-terminal domain [IPR004367] 0.743803033158579 1.7559300108686042 0.0791003598856421 1.0 0.3728726173849102 4 P20248,O95067 2 +Sec7 domain [IPR000904] 0.8901099509845177 1.7459651992847187 0.0808169991823679 1.0 0.374500969459324 3 Q9Y6D5 1 +Cullin homology domain [IPR016158] 0.6404841148262088 1.733921056040636 0.0829320912904783 1.0 0.374500969459324 7 Q13619,Q13618,Q93034,Q13617,Q14999 5 +Cullin protein, neddylation domain [IPR019559] 0.6404841148262088 1.733921056040636 0.0829320912904783 1.0 0.374500969459324 7 Q13619,Q13618,Q93034,Q13617,Q14999 5 +Glutathione S-transferase, C-terminal [IPR004046] 0.5620297131932417 1.7323626757524877 0.0832090091068835 1.0 0.3750678926090392 10 P21266,P26640,P07814,Q13155,P78417,P28161,P26641 7 +Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.6140966719591163 1.7308929642066964 0.0834708567466315 1.0 0.3750678926090392 8 Q8N8N7,Q00796,Q8N4Q0 3 +HR1 rho-binding domain [IPR011072] 0.7203556185356913 1.6534259535923888 0.0982442044286271 1.0 0.4026911505833037 4 O75116 1 +Gelsolin-like domain [IPR007123] 0.6749327756199552 1.6111754220610142 0.1071414931665866 1.0 0.4172562434796279 5 Q15436,O95487,Q13045,P53992 4 +Ubiquitin-like domain [IPR000626] 0.5398671259322083 1.6106142965639587 0.1072638158045315 1.0 0.4172562434796279 16 Q86UV5,Q99426,Q8NCF5,Q15813,Q96S82 5 +Cyclin-like [IPR013763] 0.669863889041874 1.5880517146502922 0.11227464558144 1.0 0.4261696673231063 5 P20248,O95067 2 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.5819788747014808 1.5662892321980235 0.1172809206882989 1.0 0.4374739000469015 8 O95630,Q92905,Q7L5N1 3 +Polyketide synthase, enoylreductase domain [IPR020843] 0.6033084648846859 1.5512137358380125 0.1208504714810458 1.0 0.4487436712540029 7 Q00796,Q8N4Q0 2 +Exportin-1/Importin-beta-like [IPR013598] 0.6962501438361415 1.5473816134077567 0.1217712522296246 1.0 0.4505205432354182 4 Q9HAV4 1 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.6244061569157512 1.5374291711688115 0.1241882474248328 1.0 0.4520917082056414 6 Q8N4Q0 1 +SUI1 domain [IPR001950] 0.8351976159939574 1.5348166214314023 0.1248288787861264 1.0 0.4532120492461632 3 P41567 1 +W2 domain [IPR003307] 0.5931844097945776 1.5011159289179743 0.1333255795338011 1.0 0.4727155638939327 7 P78344,Q13144,O43432,Q04637 4 +Cold-shock (CSD) domain [IPR019844] 0.8226336219766912 1.4862495897566452 0.1372131151207933 1.0 0.4753579039108401 3 P67809,Q9Y2V2 2 +Rab-GTPase-TBC domain [IPR000195] 0.6082610359304451 1.4605744190562486 0.144132270763059 1.0 0.483535291453032 6 Q8TC07,O60343,Q9Y3P9 3 +Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0.6081964078310158 1.4602662483536326 0.1442169142982829 1.0 0.483535291453032 6 P26640,Q9P2J5 2 +Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0.6081964078310158 1.4602662483536326 0.1442169142982829 1.0 0.483535291453032 6 P26640,Q9P2J5 2 +Sec23/Sec24 beta-sandwich [IPR012990] 0.6747311827956942 1.4522739982391095 0.1464254343483655 1.0 0.4838791962749991 4 Q15436,O95487,P53992 3 +Sec23/Sec24, trunk domain [IPR006896] 0.6747311827956942 1.4522739982391095 0.1464254343483655 1.0 0.4838791962749991 4 Q15436,O95487,P53992 3 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.6747311827956942 1.4522739982391095 0.1464254343483655 1.0 0.4838791962749991 4 Q15436,O95487,P53992 3 +Sec23/Sec24, helical domain [IPR006900] 0.6747311827956942 1.4522739982391095 0.1464254343483655 1.0 0.4838791962749991 4 Q15436,O95487,P53992 3 +Initiation factor eIF-4 gamma, MA3 [IPR003891] 0.6052971952719385 1.446437918816554 0.1480544128002361 1.0 0.4867448706673284 6 Q9HCG8,P78344,Q04637,O43432 4 +NADP-dependent oxidoreductase domain [IPR023210] 0.6669224230040743 1.4176864033354415 0.1562823414497121 1.0 0.4936323336551802 4 O43488,P48507 2 +PIN domain [IPR002716] 0.8000248581350862 1.3987226005522624 0.1618961841759638 1.0 0.5026719606740588 3 Q9Y2L1 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.7990444908927913 1.3949249563208863 0.1630384705215839 1.0 0.5044929036707648 3 P08243,Q06210 2 +Glutamine amidotransferase [IPR017926] 0.7978501045088165 1.390298139604998 0.1644383625635403 1.0 0.5070055322761909 3 P27708,P17812 2 +Kinesin-associated [IPR032405] 0.7931562233389629 1.3721140169553463 0.1700279465840035 1.0 0.5168000588423679 3 Q15058 1 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.4968233010978825 1.3588352836459348 0.1741987898800912 1.0 0.5241362484458434 17 Q86UV5,Q9UPT9,O94966,Q96K76,Q93008,P45974,P51784,Q96RU2,P40818 9 +Ubiquitin specific protease domain [IPR028889] 0.4968233010978825 1.3588352836459348 0.1741987898800912 1.0 0.5241362484458434 17 Q86UV5,Q9UPT9,O94966,Q96K76,Q93008,P45974,P51784,Q96RU2,P40818 9 +Chaperone DnaJ, C-terminal [IPR002939] 0.6197438312667938 1.3581063163317844 0.1744299512651739 1.0 0.5242524914956607 5 P31689 1 +BAT2, N-terminal [IPR009738] 0.7888826629461005 1.3555577382172386 0.1752399261010258 1.0 0.5261061948986695 3 Q5JSZ5 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.6511007585750637 1.3475303592901573 0.1778094824924099 1.0 0.5320606822272881 4 P13674,Q9GZT9 2 +PurM-like, C-terminal domain [IPR010918] 0.7860819772701744 1.3447078200782652 0.178719608266858 1.0 0.5336483201246517 3 P49903 1 +MPN domain [IPR037518] 0.4937785441262995 1.3425883238431773 0.1794053132228716 1.0 0.5340149486996082 11 O95630,Q92905,Q8TAT6,Q7L5N1 4 +Exportin-2, central domain [IPR013713] 0.7793371155568831 1.3185810080812066 0.1873092264282383 1.0 0.5472564630516019 3 P55060,O15397 2 +Anticodon-binding [IPR004154] 0.6404738575713097 1.3003813900171104 0.1934702850336163 1.0 0.5507451722657166 4 P26639,P07814 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.5526708750354707 1.2997420447794308 0.1936893948417433 1.0 0.5507451722657166 7 O43318,Q13418,P41240,Q13546 4 +Phosphofructokinase domain [IPR000023] 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.5507451722657166 3 P17858,P08237 2 +La-type HTH domain [IPR006630] 0.6065132954885105 1.297174919117771 0.1945710083435987 1.0 0.5507451722657166 5 Q92615,Q71RC2,Q6PKG0,P05455 4 +TGS [IPR004095] 0.5636848416996695 1.247436028819971 0.2122376627987972 1.0 0.5808272922624369 6 P26639,Q9NTK5 2 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.5948347423440887 1.2433878230731974 0.2137249552921662 1.0 0.5831393319244177 5 P62191,P62195,P43686 3 +Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768] 0.625805390123335 1.2353187736006357 0.2167118894391095 1.0 0.588481725195722 4 Q9Y613 1 +Formin, FH2 domain [IPR015425] 0.625805390123335 1.2353187736006357 0.2167118894391095 1.0 0.588481725195722 4 Q9Y613 1 +Rhodanese-like domain [IPR001763] 0.5388598767511812 1.2309699742196174 0.2183340944422376 1.0 0.5896369504563573 7 Q99956,P40818 2 +IMP dehydrogenase/GMP reductase [IPR001093] 0.756345177664961 1.2296062767997211 0.2188445784100006 1.0 0.5896369504563573 3 Q9P2T1,P20839 2 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.5588762701733442 1.2244224959854697 0.2207928872566396 1.0 0.5911691563420153 6 Q9P0V9,Q16181,Q14141,Q9UHD8,Q15019 5 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7527620185129902 1.215760641770766 0.2240761158609405 1.0 0.5941180754521335 3 Q06787,P51114 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7527620185129902 1.215760641770766 0.2240761158609405 1.0 0.5941180754521335 3 Q06787,P51114 2 +Fxr1, tudor domain [IPR041560] 0.7527620185129902 1.215760641770766 0.2240761158609405 1.0 0.5941180754521335 3 Q06787,P51114 2 +Agenet-like domain [IPR008395] 0.7527620185129902 1.215760641770766 0.2240761158609405 1.0 0.5941180754521335 3 Q06787,P51114 2 +Pleckstrin homology domain [IPR001849] 0.4459263956876533 1.210901935705102 0.2259329906701959 1.0 0.5984586902674547 31 O15020,P50570,Q96AC1,P19174,P31751,P22059,Q14155,Q9BZF3,O75116,Q96TA1,O60333 11 +OTU domain [IPR003323] 0.7485816661689942 1.199617287787316 0.2302880093251627 1.0 0.6039902265820368 3 Q96FW1,Q01804 2 +CAP Gly-rich domain [IPR000938] 0.7473872797849909 1.195007033159566 0.2320842822407192 1.0 0.6057885544974674 3 Q15813,Q99426 2 +WHEP-TRS domain [IPR000738] 0.6140979689366711 1.1834507667617042 0.2366305476163019 1.0 0.6131885937715773 4 P07814,P41250,P23381 3 +Sterile alpha motif domain [IPR001660] 0.5492992963881139 1.1786142498031638 0.2385518148086993 1.0 0.6168818534891627 6 Q9Y3Z3,O15357 2 +Cold shock domain [IPR011129] 0.6116460768947322 1.1725992694492262 0.2409565425212139 1.0 0.6189855332879863 4 P67809,Q9Y2V2 2 +Cold-shock protein, DNA-binding [IPR002059] 0.6116460768947322 1.1725992694492262 0.2409565425212139 1.0 0.6189855332879863 4 P67809,Q9Y2V2 2 +Forkhead-associated (FHA) domain [IPR000253] 0.4638087857664553 1.166846499680835 0.2432723647050485 1.0 0.6218030092714633 12 Q5SW79,P85037,Q15058,O60333 4 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.7396955810754009 1.165343105415718 0.2438801373124945 1.0 0.6218030092714633 3 P31689 1 +MIF4G-like, type 3 [IPR003890] 0.5010820503496916 1.1472249166853064 0.251288676175069 1.0 0.6307078107763767 8 Q9HCG8,Q9HAU5,Q04637,O43432 4 +Protein kinase, C-terminal [IPR017892] 0.5368252277253541 1.119044592428164 0.2631211156826232 1.0 0.6402848954457399 6 P31751 1 +Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.5365428552851084 1.1176978841808527 0.2636960467274107 1.0 0.6411110136060174 6 O94973,Q10567,O43747,Q9UJY4 4 +KOW [IPR005824] 0.5658798924410054 1.1103110552247617 0.2668650108509909 1.0 0.644785647335624 5 P61254,P62701,O00267,Q92917 4 +Ras GTPase-activating domain [IPR001936] 0.5953978907436355 1.1008323861210034 0.2709696136635287 1.0 0.6500883330447477 4 P21359,Q14C86 2 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.5940279079776373 1.0947952617222738 0.2736063427553663 1.0 0.6513033088429727 4 Q8TEA1,Q08J23 2 +Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314] 0.5305312262177945 1.089050031732171 0.2761318232062195 1.0 0.6547411284575926 6 P26639,P49591,P07814 3 +Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099] 0.7148402508211387 1.069881056563748 0.2846728509229554 1.0 0.6593118814391552 3 P11908,O60256 2 +DMAP1-binding domain [IPR010506] 0.9471641791044784 1.068918184945602 0.2851065370083685 1.0 0.6593118814391552 2 Q9P265 1 +CRAL-TRIO lipid binding domain [IPR001251] 0.5555144658296028 1.0628799973513543 0.2878363751472632 1.0 0.6628575180407755 5 P21359 1 +CTLH, C-terminal LisH motif [IPR006595] 0.5544796973019939 1.05815395150125 0.2899852610375533 1.0 0.6632007490724322 5 Q9UL63,O94967 2 +Helicase superfamily 1/2, ATP-binding domain [IPR014001] 0.2936422152035985 1.0506828469807357 0.2934042766468168 1.0 0.6649930213506977 70 Q9H6S0,O14981,Q7Z478,Q9H4L7,P38935,Q6P158,P26196,P46063,Q92499,Q92620,O60231,Q9NUL7,Q8IX18,O14646,Q14240,Q7L014,Q86WJ1,Q9Y620,Q15477,Q14527 20 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.6649930213506977 3 P20585,P52701 2 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.6649930213506977 3 P20585,P52701 2 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.6649930213506977 3 P20585,P52701 2 +DNA mismatch repair protein MutS, core [IPR007696] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.6649930213506977 3 P20585,P52701 2 +Rpn11/EIF3F, C-terminal [IPR024969] 0.5837288736979109 1.0494988849068794 0.2939485681869684 1.0 0.6649930213506977 4 Q7L5N1 1 +Dynamin, N-terminal [IPR045063] 0.4993226666417658 1.0348701947739476 0.3007295356537258 1.0 0.6730627186112506 7 O00429,Q9H4M9 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.4993226666417658 1.0348701947739476 0.3007295356537258 1.0 0.6730627186112506 7 O00429,Q9H4M9 2 +B-box, C-terminal [IPR003649] 0.577929812368369 1.0240726250286618 0.3058009732715143 1.0 0.681313961595505 4 Q9UPN9 1 +14-3-3 domain [IPR023410] 0.4968568382531855 1.0227204740233795 0.3064400281565951 1.0 0.681728918848373 7 P31946,P27348 2 +Dynamin, GTPase domain [IPR001401] 0.7004895721675375 1.0151380167897437 0.3100400418736742 1.0 0.6861605606234764 3 O00429 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4733469336011313 1.0043711605021466 0.315199745446129 1.0 0.6863890144172395 8 Q9GZT9,Q32P28,P13674 3 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4733469336011313 1.0043711605021466 0.315199745446129 1.0 0.6863890144172395 8 Q9GZT9,Q32P28,P13674 3 +Proteasome component (PCI) domain [IPR000717] 0.4371279191494158 1.0038710241620694 0.3154407847013147 1.0 0.6863890144172395 17 P60228,Q9BT78,P48556,O00232,Q99627,O43242,Q15008,O00231,Q9Y262,P61201,Q9UNM6,Q14152 12 +Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186] 0.5112489607360999 0.9975527468638286 0.3184962842646117 1.0 0.6863890144172395 6 O00743,Q08209 2 +Sec7, C-terminal [IPR015403] 0.9194029850746288 0.9742921488159736 0.3299115018187506 1.0 0.6979922302605073 2 Q9Y6D5 1 +Mon2, dimerisation and cyclophilin-binding domain [IPR032629] 0.9194029850746288 0.9742921488159736 0.3299115018187506 1.0 0.6979922302605073 2 Q9Y6D5 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.5350438269932318 0.9697731337261576 0.3321595872672218 1.0 0.7005968676441867 5 Q9HCE1,P42694,P38935 3 +Translational (tr)-type GTP-binding domain [IPR000795] 0.4270910737892654 0.9532762782360464 0.3404501073039148 1.0 0.7131120324527384 13 Q05639,O60841,P46199,Q9Y450,Q7Z2Z2,P13639 6 +Butyrophylin-like, SPRY domain [IPR003879] 0.5589565590369105 0.941388419729212 0.346505845831395 1.0 0.718063484169626 4 P19474,Q14258 2 +SPRY-associated [IPR006574] 0.5589565590369105 0.941388419729212 0.346505845831395 1.0 0.718063484169626 4 P19474,Q14258 2 +FYVE zinc finger [IPR000306] 0.5564731041616555 0.9306333006170684 0.3520432826345827 1.0 0.7251239475143486 4 Q7Z3T8 1 +Zinc finger, FYVE-related [IPR017455] 0.5564731041616555 0.9306333006170684 0.3520432826345827 1.0 0.7251239475143486 4 Q7Z3T8 1 +Peptidase S9A, N-terminal domain [IPR023302] 0.9044776119403012 0.9240490677465596 0.3554607693089031 1.0 0.7272123777822264 2 P48147 1 +Sec24-like, trunk domain [IPR041742] 0.6745297103612975 0.9170966119412608 0.3590920163030204 1.0 0.7289977320908947 3 O95487,P53992 2 +Kinesin motor domain [IPR001752] 0.4210467622236042 0.9153255041483546 0.3600207739005858 1.0 0.7289977320908947 14 Q99661,Q15058,P33176,Q96Q89,P52732,O60333 6 +Pre-PUA domain [IPR041366] 0.9005970149253746 0.9110698749405024 0.36225855800685 1.0 0.7289977320908947 2 Q9ULC4 1 +DOCKER domain [IPR027357] 0.9002985074626868 0.9100729988855968 0.3627840131958484 1.0 0.7289977320908947 2 Q96N67 1 +C2 DOCK-type domain [IPR027007] 0.9002985074626868 0.9100729988855968 0.3627840131958484 1.0 0.7289977320908947 2 Q96N67 1 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058] 0.6723616233013451 0.9089784685991878 0.3633614913980616 1.0 0.7289977320908947 3 P47897 1 +PUA domain [IPR002478] 0.5483708176820392 0.8956729692069613 0.3704274512222105 1.0 0.7336434983402143 4 Q9ULC4 1 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5477897252090665 0.8931736378244028 0.3717641932373488 1.0 0.7353250085375052 4 Q9UNH7,O60749,Q9Y5X3 3 +Kinesin-like [IPR022164] 0.6642454103117404 0.878699896986761 0.3795640145331049 1.0 0.7463311124004824 3 O60333 1 +R3H domain [IPR001374] 0.5441124697425685 0.8773839086281676 0.3802781503079275 1.0 0.7466558426097455 4 P38935 1 +PB1 domain [IPR000270] 0.8889552238805982 0.8723607808096133 0.3830115889762182 1.0 0.7466558426097455 2 Q92734 1 +USP8 dimerisation domain [IPR015063] 0.8877611940298522 0.8684109872397082 0.3851693821335042 1.0 0.7486197198783241 2 P40818 1 +Aminoacyl-tRNA synthetase, class II [IPR006195] 0.4074129594159117 0.8484076443584764 0.3962109868735299 1.0 0.7532506097718717 12 Q96I59,O43776,P26639,P49591,P07814,P41250,Q9Y285 7 +DNA2/NAM7 helicase, helicase domain [IPR041677] 0.5366157652510599 0.8453441429105362 0.3979187214327291 1.0 0.7540241325409335 4 P38935 1 +Putative RNA methylase domain [IPR000241] 0.8797014925373161 0.8418552240337549 0.3998689960634611 1.0 0.7545691450317428 2 Q7Z4G4 1 +Translation initiation factor IF- 2, domain 3 [IPR023115] 0.8743283582089582 0.8242576731011066 0.4097931632890517 1.0 0.7637691879781573 2 P46199 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.6467602269334016 0.8141388423268481 0.4155654162901436 1.0 0.7697854616041232 3 Q99797,P52888 2 +SNF2, N-terminal [IPR000330] 0.4041427199898629 0.8133053976450506 0.4160429831280119 1.0 0.770146188346415 18 Q86WJ1,Q9H4L7,O14646,Q9Y620,Q14527,O14981,Q2NKX8 7 +Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211] 0.86776119402985 0.8028716489143956 0.4220489242433127 1.0 0.774662372629514 2 P09960 1 +Peptidase M24 [IPR000994] 0.4512337743339317 0.8014599775437065 0.4228654049415166 1.0 0.774662372629514 7 P50579,Q9Y5B9,Q9UQ80,Q9NQW7 4 +Zinc finger, CCCH-type [IPR000571] 0.401552889419369 0.7985815457026799 0.4245330918136627 1.0 0.7753209986643887 18 Q9UPT8,Q6P158,Q8IWR0 3 +Zinc finger, UBP-type [IPR001607] 0.5238545397297218 0.7913249756684337 0.4287543775842495 1.0 0.7807473452056435 4 Q9UPT9 1 +MIT domain [IPR007330] 0.6398925052254393 0.7890639080290522 0.4300746552243941 1.0 0.7822934443393623 3 O75351,Q8N0X7 2 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.6360107494774446 0.774969217349621 0.4383578493560134 1.0 0.7889282378033209 3 Q13310,O95071 2 +B-box-type zinc finger [IPR000315] 0.4621870694081395 0.7696371834419387 0.4415151417223961 1.0 0.7909511387566347 6 P19474,Q9UPN9 2 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.8561194029850776 0.7653119830281717 0.4440857901840838 1.0 0.7934682458472836 2 Q9NVE7 1 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.6316709980173856 0.7592819123692044 0.4476839351414199 1.0 0.7944730490274722 3 Q86UV5 1 +GTP binding domain [IPR006073] 0.3885855568262256 0.7402730639210873 0.4591343217358341 1.0 0.7993751650170564 13 P36915,Q8N3Z3,Q8TCY9,Q9NTK5 4 +Translation elongation factor EFTu-like, domain 2 [IPR004161] 0.4011752071776002 0.7320981697814107 0.4641086508403134 1.0 0.8054607114328702 9 Q05639,O60841,Q9Y450 3 +AP complex, mu/sigma subunit [IPR022775] 0.4528912870668778 0.7276959749189682 0.4667997148307088 1.0 0.8071821801687163 6 Q9Y2T2,P48444 2 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.8429850746268688 0.7235235799395275 0.4693582726192451 1.0 0.8071821801687163 2 Q9UID3 1 +Helicase, C-terminal [IPR001650] 0.2643358397260754 0.7184453411924289 0.4724827384466572 1.0 0.8096469272580672 70 Q9H6S0,O14981,Q7Z478,Q9H4L7,Q6P158,P26196,P46063,Q92499,Q92620,O60231,Q9NUL7,Q8IX18,O14646,Q14240,Q7L014,Q86WJ1,Q9Y620,Q15477,Q14527 19 +Ras-associating (RA) domain [IPR000159] 0.6186921469095248 0.712842438510467 0.4759432613999086 1.0 0.8120260030024756 3 P55196,Q15036 2 +Translation elongation factor EFTu/EF1A, C-terminal [IPR004160] 0.5030323248210937 0.7048760919381603 0.4808873497644577 1.0 0.8154803891536159 4 Q9Y450 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.8325373134328388 0.6907680710753387 0.4897113036422458 1.0 0.8206054645032833 2 Q9BSJ2 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.8325373134328388 0.6907680710753387 0.4897113036422458 1.0 0.8206054645032833 2 Q9BSJ2 1 +ERM family, FERM domain C-lobe [IPR041789] 0.6118244252015479 0.6885817270541305 0.491086523427058 1.0 0.8212248318319908 3 P35241,P15311 2 +EH domain [IPR000261] 0.4432160104645453 0.6846228976925147 0.4935819141025739 1.0 0.8235438431993314 6 Q9H4M9 1 +SUN domain [IPR012919] 0.6045720039645333 0.6632176703963942 0.5071911559647286 1.0 0.8331167126556872 3 Q9UH99 1 +Peptidase M16, middle/third domain [IPR032632] 0.8208955223880631 0.65482040107334 0.5125833939694444 1.0 0.8377938666139237 2 O43847 1 +Poly(ADP-ribose) polymerase, catalytic domain [IPR012317] 0.6001791579575952 0.6479895243171794 0.5169917258043286 1.0 0.8407661101950564 3 Q9UGN5,P09874 2 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.3839344647385527 0.6464437078418075 0.5179920420035278 1.0 0.8407661101950564 9 Q13535 1 +GHMP kinase N-terminal domain [IPR006204] 0.8179104477611944 0.6457022495833433 0.5184722034305786 1.0 0.8407661101950564 2 P53602 1 +Dynamin stalk domain [IPR000375] 0.8173134328358231 0.6438836476654733 0.5196508863232758 1.0 0.8407661101950564 2 O00429 1 +GTPase effector domain [IPR020850] 0.8173134328358231 0.6438836476654733 0.5196508863232758 1.0 0.8407661101950564 2 O00429 1 +Dynamin GTPase effector [IPR003130] 0.8173134328358231 0.6438836476654733 0.5196508863232758 1.0 0.8407661101950564 2 O00429 1 +Nuclear transport factor 2, eukaryote [IPR018222] 0.4866226451664395 0.6385608526591092 0.523108655061518 1.0 0.8413614103558852 4 P61970 1 +Nuclear transport factor 2 domain [IPR002075] 0.4866226451664395 0.6385608526591092 0.523108655061518 1.0 0.8413614103558852 4 P61970 1 +Heat shock chaperonin-binding [IPR006636] 0.5921170498656232 0.6203225035057646 0.5350454822049702 1.0 0.8453118600093612 3 Q9NRR5,P54727 2 +FDF domain [IPR019050] 0.8092537313432862 0.619500873935152 0.5355864463647699 1.0 0.8453118600093612 2 Q96F86 1 +DFDF domain [IPR025762] 0.8092537313432862 0.619500873935152 0.5355864463647699 1.0 0.8453118600093612 2 Q96F86 1 +Lsm14-like, N-terminal [IPR025609] 0.8092537313432862 0.619500873935152 0.5355864463647699 1.0 0.8453118600093612 2 Q96F86 1 +Calcineurin-like phosphoesterase domain, ApaH type [IPR004843] 0.4117004286857254 0.6189386555132372 0.5359567719231229 1.0 0.8453118600093612 7 O00743,Q08209 2 +Endonuclease/exonuclease/phosphatase [IPR005135] 0.4249753522771787 0.6053124749109934 0.5449713940749328 1.0 0.8545175299066776 6 Q01968,O15357,P27695 3 +SH3 domain [IPR001452] 0.3345622855742094 0.6018232536549861 0.5472917946141238 1.0 0.8556651856286427 38 Q9UQB8,P19174,P41240,Q14185,Q14155,A1X283,Q92796 7 +Methylglyoxal synthase-like domain [IPR011607] 0.802985074626868 0.6007604046163129 0.5479995800840867 1.0 0.8556651856286427 2 P31939 1 +Nucleoside diphosphate kinase-like domain [IPR034907] 0.8023880597014958 0.5989861469133185 0.5491821225229754 1.0 0.8559948023068472 2 P15531 1 +XPG, N-terminal [IPR006085] 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.8689688408771673 2 Q9UQ84 1 +XPG-I domain [IPR006086] 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.8689688408771673 2 Q9UQ84 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.7847761194029863 0.5475140528601696 0.5840256185946906 1.0 0.8775601985237365 2 P35611 1 +Serine/threonine-protein kinase N, first HR1 domain [IPR037313] 0.7820895522388105 0.5398164064803311 0.5893236514081743 1.0 0.8810645166585322 2 Q16512 1 +Serine/threonine-protein kinase N, C2 domain [IPR037784] 0.7820895522388105 0.5398164064803311 0.5893236514081743 1.0 0.8810645166585322 2 Q16512 1 +Nucleoside phosphorylase domain [IPR000845] 0.7800000000000056 0.5338587902352129 0.593439235364994 1.0 0.8825423472959469 2 Q13126 1 +Zinc finger, MYND-type [IPR002893] 0.7788059701492562 0.5304661368635328 0.5957887815119012 1.0 0.8828349672445195 2 Q9GZT9 1 +Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.8828349672445195 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.8828349672445195 2 P22314 1 +Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.8828349672445195 2 P22314 1 +Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.8828349672445195 2 P22314 1 +Condensin complex subunit 1, C-terminal [IPR032682] 0.774626865671644 0.5186598008993106 0.6039979990825195 1.0 0.8846113806264474 2 P42695 1 +Formin, FH3 domain [IPR010472] 0.5613616004777582 0.5185503231240423 0.6040743587469968 1.0 0.8846113806264474 3 O60610,O60879 2 +Formin, GTPase-binding domain [IPR010473] 0.5613616004777582 0.5185503231240423 0.6040743587469968 1.0 0.8846113806264474 3 O60610,O60879 2 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.5606557167962374 0.5162922950376241 0.6056502767956808 1.0 0.8846113806264474 3 Q92688 1 +EB1, C-terminal [IPR004953] 0.7728358208955245 0.5136327346012515 0.6075087886601156 1.0 0.8855708948187874 2 Q15555 1 +Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.7704477611940316 0.506961059038327 0.6121821418948656 1.0 0.8877959665381567 2 O95336 1 +Zinc finger, LIM-type [IPR001781] 0.3511815734370294 0.4932444019485032 0.6218399076996854 1.0 0.8926041479526851 9 Q9NR12,Q9UHB6,Q16527,Q14847,Q9UGI8,Q96HC4,Q13642,Q9UGP4 8 +CLASP N-terminal domain [IPR024395] 0.7605970149253751 0.4798254659892128 0.6313515032668231 1.0 0.8992936428471932 2 Q7Z460 1 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.7585074626865692 0.4741511527092421 0.6353921236302758 1.0 0.9030129189171404 2 Q9UPN9 1 +CS domain [IPR007052] 0.3465944710646828 0.4730238863454064 0.6361961377820649 1.0 0.9036839244551708 9 Q96RS6,O94966,Q9HB71,Q9UHD1,Q9Y266,Q15185 6 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.7570149253731365 0.4701159914928866 0.6382721496265926 1.0 0.9038112824576124 2 P47897 1 +K Homology domain, type 1 [IPR004088] 0.3371933839193467 0.4648851829776824 0.6420136818572888 1.0 0.9053518029649122 25 Q9NZI8,Q00341,Q8IWZ3,O00425,P51114,Q9UNW9,Q96PU8,Q15366,Q96AE4,Q15365,O75179,Q06787,Q9Y6M1,P51116 14 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7525373134328381 0.4581013270201918 0.6468796455922523 1.0 0.9064259524969628 2 P51114 1 +Sirtuin family, catalytic core domain [IPR026590] 0.7492537313432872 0.449378486729705 0.6531586478045197 1.0 0.9088150219579496 2 Q96EB6 1 +MAGE homology domain [IPR002190] 0.5365780830098551 0.4416600588173265 0.6587352164636227 1.0 0.9114211304534914 3 Q96MG7,Q9UNF1 2 +WH2 domain [IPR003124] 0.5362794864138644 0.4407653284533885 0.6593828964353206 1.0 0.9114211304534914 3 O00401,Q27J81 2 +Nucleotidyl transferase domain [IPR005835] 0.741791044776122 0.4298373654569697 0.6673139501175673 1.0 0.9126472537207796 2 Q96IJ6 1 +OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.4055944794710539 0.4288467032262157 0.6680347885054678 1.0 0.9126472537207796 5 Q9NTK5 1 +Phox homology [IPR001683] 0.3239887413820372 0.4273086639970337 0.669154523105117 1.0 0.9126472537207796 12 Q53T59,Q9Y5X3,O60493,A1X283,O00443,Q15036 6 +Threonyl/alanyl tRNA synthetase, SAD [IPR012947] 0.4046100119999206 0.4253009717805071 0.6706172852413437 1.0 0.9126472537207796 5 P26639 1 +TATA-binding protein interacting (TIP20) [IPR013932] 0.737014925373137 0.4175427599539981 0.6762814546362641 1.0 0.9126472537207796 2 Q86VP6 1 +Peptidase M16, C-terminal [IPR007863] 0.3628065543212472 0.4147098710959013 0.6783543053257144 1.0 0.9126472537207796 7 O43847 1 +Peptidase M16, N-terminal [IPR011765] 0.3628065543212472 0.4147098710959013 0.6783543053257144 1.0 0.9126472537207796 7 O43847 1 +Inositol polyphosphate-related phosphatase [IPR000300] 0.7352238805970177 0.4129757958641949 0.6796243471872261 1.0 0.913433907892802 2 O15357 1 +Helicase/UvrB, N-terminal [IPR006935] 0.5219127648060499 0.3986830915183345 0.69012672815506 1.0 0.9204552365092286 3 Q9UPY3 1 +Zinc finger, CCHC-type [IPR001878] 0.3436140966750429 0.3977668960958642 0.6908020211952697 1.0 0.9206179445361172 8 Q9NUD5 1 +Zinc finger, C3HC4 RING-type [IPR018957] 0.3716197100240807 0.3928517953336423 0.6944289466710041 1.0 0.9206998115621252 6 Q5VTR2,O75150 2 +NECAP, PHear domain [IPR012466] 0.7271641791044805 0.392724501258197 0.6945229722955284 1.0 0.9206998115621252 2 Q9NVZ3 1 +Ribosomal RNA methyltransferase FtsJ domain [IPR002877] 0.5148004308100353 0.3785813655935691 0.7049987620192584 1.0 0.9270312180474248 3 Q8N1G2 1 +Phospholipase/carboxylesterase/thioesterase [IPR003140] 0.5135861451179451 0.3751998718259736 0.7075118255128636 1.0 0.9285654536156704 3 Q5VWZ2,O75608 2 +PTB/PI domain [IPR006020] 0.71940298507463 0.3736988767503628 0.708628361106669 1.0 0.9288449480195496 2 O60343 1 +Amine oxidase [IPR002937] 0.5120931621379533 0.3710627975219139 0.710590759365189 1.0 0.9293974949600832 3 Q8NB78,P50336 2 +Mad3/Bub1 homology region 1 [IPR013212] 0.7140298507462719 0.3608084868595432 0.7182426179856931 1.0 0.9325372080788532 2 O60566 1 +Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.7125373134328392 0.3572694184870258 0.7208901217726731 1.0 0.9347541912318996 2 Q9Y237 1 +Dbl homology (DH) domain [IPR000219] 0.3310900072761223 0.3503150639217083 0.7261022612985462 1.0 0.9379367932551612 8 Q9H8V3,Q14155 2 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.7095522388059735 0.350246193550689 0.7261539421039882 1.0 0.9379367932551612 2 P52701 1 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.5007443726159533 0.340372939530669 0.7335756945547605 1.0 0.9384882817655004 3 O00203 1 +PPM-type phosphatase domain [IPR001932] 0.4034725683324821 0.3401112568082446 0.7337727448671487 1.0 0.9384882817655004 4 O15355 1 +NFkappaB IPT domain [IPR033926] 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.94024293125583 2 Q00653 1 +Rel homology dimerisation domain [IPR032397] 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.94024293125583 2 Q00653 1 +Rel homology domain (RHD), DNA-binding domain [IPR011539] 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.94024293125583 2 Q00653 1 +HDGF-related, PWWP domain [IPR035496] 0.4984749813086969 0.3344006183824224 0.7380772728381229 1.0 0.94024293125583 3 Q7Z4V5 1 +ABC-transporter extension domain [IPR032781] 0.7005970149253766 0.3296227770929676 0.7416850099924113 1.0 0.9417928265291492 2 Q9UG63 1 +Coatomer, WD associated region [IPR006692] 0.6958208955223917 0.3189024780600935 0.749800465140211 1.0 0.9452345678596272 2 P53621 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.695522388059705 0.3182389970223843 0.7503036538396013 1.0 0.9454312121264388 2 O15027 1 +Anaphase-promoting complex subunit 4, WD40 domain [IPR024977] 0.3215777299641357 0.3163158275129055 0.7517627988308879 1.0 0.946831684188949 8 O94967,O75717,P53621,Q8TEQ6 4 +Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750] 0.6886567164179145 0.303193768441742 0.761742197714449 1.0 0.9499269013204996 2 Q9H1B7 1 +DEAD/DEAH box helicase domain [IPR011545] 0.2517496383343889 0.2935159920411958 0.7691277776311709 1.0 0.9500300880061604 47 Q7Z478,Q9NUL7,Q14240,Q6P158,P26196,Q8IX18,P46063,Q92499,Q92620,Q15477,O60231,Q9H6S0,Q7L014 13 +K Homology domain [IPR004087] 0.2990086387819794 0.291588116703857 0.770601562287782 1.0 0.9500300880061604 24 Q8IWZ3,P51114,Q96PU8,Q96AE4,O75179,Q06787,P51116 7 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844] 0.3845266959074082 0.2841634045105543 0.7762851588851052 1.0 0.952173192632496 4 O95394 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.6776119402985146 0.2798693688715468 0.7795777285666874 1.0 0.9544919761182956 2 Q13432 1 +F-box domain [IPR001810] 0.3595839019676073 0.2780679900298438 0.7809601673247089 1.0 0.9545873125072524 5 Q13309 1 +GTP binding protein, second domain [IPR031662] 0.6725373134328403 0.2695233565473214 0.7875269710646449 1.0 0.9552053194695004 2 Q9Y295 1 +Peptidase M20, dimerisation domain [IPR011650] 0.6689552238806014 0.2623629204849295 0.7930416567993537 1.0 0.955416156417612 2 Q8IYS1 1 +ZU5 domain [IPR000906] 0.4667064795461374 0.2569432487289069 0.7972225833960669 1.0 0.955416156417612 3 Q07157,Q12955 2 +Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.6656716417910493 0.2559037427578756 0.7980251645306089 1.0 0.955416156417612 2 P54136 1 +DALR anticodon binding [IPR008909] 0.6656716417910493 0.2559037427578756 0.7980251645306089 1.0 0.955416156417612 2 P54136 1 +Ariadne domain [IPR045840] 0.6644776119403031 0.2535798763499812 0.7998201449183269 1.0 0.955416156417612 2 O95376 1 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.6626865671641837 0.250119098336586 0.8024952469464777 1.0 0.9563214693370936 2 Q96RQ1 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.6626865671641837 0.250119098336586 0.8024952469464777 1.0 0.9563214693370936 2 Q96RQ1 1 +CSN8/PSMD8/EIF3K [IPR033464] 0.456197488830496 0.2339823577427622 0.8149986750178349 1.0 0.9591984924090649 3 Q99627 1 +CRIB domain [IPR000095] 0.3425486746101579 0.2310165334301057 0.8173019575946665 1.0 0.9591984924090649 5 O00401,Q13153 2 +Zinc finger, RING-type [IPR001841] 0.2765534733819542 0.2296056721324539 0.8183981989007538 1.0 0.9591984924090649 32 Q96T51,O94822,Q14258,P19474,Q14527,P22681 6 +Domain of unknown function DUF1747 [IPR013719] 0.6510447761194079 0.228361857774566 0.8193649391420901 1.0 0.9591984924090649 2 Q9Y5B9 1 +OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365] 0.3188055814061415 0.2242705134402316 0.8225468187117682 1.0 0.9591984924090649 6 Q96I59,O43776,P27694 3 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6474626865671692 0.2219267515598069 0.8243709050218504 1.0 0.9591984924090649 2 P51784 1 +GINS subunit, domain A [IPR021151] 0.646268656716423 0.2198090339500486 0.8260198836222055 1.0 0.9591984924090649 2 Q9BRT9 1 +BRO1 domain [IPR004328] 0.6444776119403044 0.2166581276177326 0.8284747821842946 1.0 0.9591984924090649 2 Q5VW32 1 +Myosin tail [IPR002928] 0.3581744062360226 0.2158414318056193 0.8291113515167894 1.0 0.9591984924090649 4 Q92614 1 +Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253] 0.6397014925373187 0.2084066737659732 0.8349114458218534 1.0 0.9596723794735782 2 O75351 1 +DUS-like, FMN-binding domain [IPR035587] 0.6382089552238859 0.2058732267266906 0.8368899394344851 1.0 0.959900257704586 2 Q6P1R4 1 +PABP, RNA recognition motif 2 [IPR045305] 0.6358208955223934 0.2018645059021103 0.8400226509936317 1.0 0.959900257704586 2 Q13310 1 +Poly(ADP-ribose) polymerase, regulatory domain [IPR004102] 0.6328358208955277 0.1969312364191351 0.8438813491735062 1.0 0.9599015990723988 2 Q9UGN5 1 +WGR domain [IPR008893] 0.6328358208955277 0.1969312364191351 0.8438813491735062 1.0 0.9599015990723988 2 Q9UGN5 1 +ARHGEF1-like, PH domain [IPR041020] 0.6283582089552293 0.1896933018075403 0.8495494698954928 1.0 0.9599015990723988 2 Q92974 1 +eRF1 domain 3 [IPR005142] 0.6241791044776177 0.1831134466311784 0.8547090052742488 1.0 0.9599015990723988 2 P62495 1 +eRF1 domain 1/Pelota-like [IPR005140] 0.6241791044776177 0.1831134466311784 0.8547090052742488 1.0 0.9599015990723988 2 P62495 1 +eRF1 domain 2 [IPR005141] 0.6241791044776177 0.1831134466311784 0.8547090052742488 1.0 0.9599015990723988 2 P62495 1 +DnaJ domain [IPR001623] 0.2630676561523553 0.1803810314916001 0.856853444750318 1.0 0.9599015990723988 19 O60884,O75937,Q99615,P31689,Q8WXX5 5 +GRAM domain [IPR004182] 0.3415818716127796 0.1789062243529867 0.8580113353149192 1.0 0.9599015990723988 4 Q13614 1 +EF-hand domain [IPR002048] 0.2385895459979986 0.1737944743902364 0.8620269871077502 1.0 0.9599015990723988 43 Q9H4M9,P19174,P17655,Q14257,Q96D71,Q96AY3 6 +Zinc finger, RanBP2-type [IPR001876] 0.2572511754965825 0.1676770861033938 0.8668373235839253 1.0 0.9599015990723988 9 Q01844 1 +Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164] 0.6104477611940359 0.1626871069409129 0.8707647989130745 1.0 0.961219522957278 2 O94973 1 +Actin-depolymerising factor homology domain [IPR002108] 0.252513636643304 0.1570783178955226 0.875183125256392 1.0 0.9628782424538002 9 Q14019,P60983,Q9UJU6,Q6IBS0,P60981 5 +Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364] 0.3088934380979206 0.1539467191116344 0.8776517466254237 1.0 0.9644786373057836 5 O43776 1 +Ran binding domain [IPR000156] 0.3264635603345232 0.149491689268216 0.8811656666861911 1.0 0.9655237049415096 4 Q9H6Z4,P49792,P43487 3 +Vicinal oxygen chelate (VOC) domain [IPR037523] 0.4057927739623794 0.1435169423119473 0.8858819317254754 1.0 0.9665494288729616 3 Q9HC38,Q04760 2 +SGS domain [IPR007699] 0.5946268656716482 0.1414081427235496 0.8875475219468942 1.0 0.9665494288729616 2 Q9HB71 1 +Thioredoxin-like fold [IPR012336] 0.5934328358209021 0.1398992613287269 0.8887395849242401 1.0 0.9665494288729616 2 Q8NBF2 1 +Calponin homology domain [IPR001715] 0.2468978551020248 0.134774789051008 0.8927899393673053 1.0 0.9665494288729616 25 O15020,Q99439,Q5VUJ6,Q15555,Q14155,Q15691 6 +RasGAP protein, C-terminal [IPR000593] 0.5862686567164245 0.1311288001059932 0.8956734186739792 1.0 0.9665494288729616 2 P46940 1 +Myosin, N-terminal, SH3-like [IPR004009] 0.2935313840629527 0.1260279980566975 0.8997097620241379 1.0 0.9680897535599272 5 P35579,Q92614 2 +Aminotransferase class V domain [IPR000192] 0.5746268656716489 0.1178977473609794 0.9061486781462122 1.0 0.9708993478754636 2 Q9Y617 1 +Diaphanous autoregulatory (DAD) domain [IPR014767] 0.5710447761194102 0.1140767217851722 0.9091769750690588 1.0 0.9720019250542 2 O60610 1 +MATH/TRAF domain [IPR002083] 0.5671641791044848 0.1100678738569565 0.9123555462654788 1.0 0.9738664417390576 2 Q93009 1 +SMCs flexible hinge [IPR010935] 0.280946201397268 0.106513660807659 0.9151748173089432 1.0 0.9754966301590734 5 Q9NTJ3 1 +Zinc finger, double-stranded RNA binding [IPR022755] 0.2900238948625924 0.0950457890182497 0.924278457139916 1.0 0.982745114717685 4 Q9ULV3,Q5F1R6,Q9UKJ3 3 +Sorting nexin, N-terminal [IPR005329] 0.5474626865671719 0.091751169055884 0.9268957417833684 1.0 0.9847589172360952 2 O60749 1 +TRIAD supradomain [IPR044066] 0.3547266661637805 0.0847807817715851 0.9324356724475078 1.0 0.9880565555315162 3 O95376 1 +IBR domain [IPR002867] 0.3547266661637805 0.0847807817715851 0.9324356724475078 1.0 0.9880565555315162 3 O95376 1 +EF-hand, Ca insensitive [IPR014837] 0.3538369662585843 0.0840282903996139 0.9330339388188572 1.0 0.9881958052912284 3 Q13813,P12814 2 +Alanyl-tRNA synthetase, class IIc, core domain [IPR018165] 0.3448790683786095 0.0769206221837897 0.9386866920194306 1.0 0.9912481063937904 3 P49588,Q9BTE6 2 +Small GTP-binding protein domain [IPR005225] 0.193575842261628 0.075894823632565 0.9395027751262122 1.0 0.9912481063937904 45 Q9Y6B6,P46199 2 +Histone deacetylase domain [IPR023801] 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 0.9925863900993742 2 Q13547 1 +NOPS [IPR012975] 0.336518363690651 0.071026998654041 0.943376267931392 1.0 0.9925863900993742 3 Q8WXF1,Q15233 2 +RII binding domain [IPR018459] 0.5161194029850831 0.0691243998591481 0.9448905991987748 1.0 0.9937957132554128 2 Q12802 1 +RNA-binding S4 domain [IPR002942] 0.3272618692146825 0.0652847256822366 0.9479473035386085 1.0 0.9950888618101892 3 P62701,P46781 2 +BRK domain [IPR006576] 0.3200955509107128 0.06136791371839 0.9510662053230644 1.0 0.9965251794617456 3 Q9HCK8,Q9P2D1 2 +AAA+ ATPase domain [IPR003593] 0.1511965926156578 0.0610654081991988 0.9513071179746724 1.0 0.9965251794617456 60 P62191,P43686,P61221,P35251,P25205,Q6PL18,Q9UG63,P38935,Q9BSD7,Q15645,Q9BVQ7,Q5T9A4,Q99741,Q8NE71,Q9NUQ8,O75351,Q8N3C0,Q14204,P62195 19 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.3159151985667253 0.0592836997672978 0.9527261439796642 1.0 0.9965251794617456 3 O00469,O60568 2 +Sec63 domain [IPR004179] 0.3087488802627585 0.0560348780440459 0.955314022138222 1.0 0.9966743610277312 3 O75643,Q8N3C0 2 +Translation initiation factor, beta propellor-like domain [IPR013979] 0.2407407407407373 0.0541713740573825 0.9567986273780172 1.0 0.9968515223540876 4 Q9BY44,Q96J01,P55884 3 +Elongation factor EFG, domain V-like [IPR000640] 0.2252763668957202 0.0526435906130314 0.95801588481606 1.0 0.9972007853035671 5 Q15029,Q7Z2Z2,Q8N442,P13639 4 +Elongation Factor G, domain II [IPR041095] 0.2314354346109865 0.0498081273375747 0.9602752900450062 1.0 0.999170659072431 4 P13639 1 +Methionyl/Leucyl tRNA synthetase [IPR015413] 0.4358208955223979 0.0392597817685146 0.968683271377639 1.0 1.0 2 P56192 1 +Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872] 0.4358208955223979 0.0392597817685146 0.968683271377639 1.0 1.0 2 P56192 1 +Methioninyl-tRNA synthetase core domain [IPR033911] 0.4358208955223979 0.0392597817685146 0.968683271377639 1.0 1.0 2 P56192 1 +BZW1/2, W2 domain [IPR043510] 0.4292537313432932 0.0380857344850357 0.9696193252904824 1.0 1.0 2 Q7L1Q6 1 +Aminopeptidase P, N-terminal [IPR007865] 0.4265671641791141 0.0376442012253712 0.9699713653983396 1.0 1.0 2 Q9NQH7 1 +Homeobox domain, metazoa [IPR020479] 0.3916417910447846 0.0335830696411578 0.9732096231221844 1.0 1.0 2 P31260 1 +CHD subfamily II, SANT-like domain [IPR009462] 0.388059701492545 0.0333099006081304 0.9734274585986482 1.0 1.0 2 Q12873 1 +Domain of unknown function DUF1087 [IPR009463] 0.388059701492545 0.0333099006081304 0.9734274585986482 1.0 1.0 2 Q12873 1 +CHD, C-terminal 2 [IPR012957] 0.388059701492545 0.0333099006081304 0.9734274585986482 1.0 1.0 2 Q12873 1 +CHD, N-terminal [IPR012958] 0.388059701492545 0.0333099006081304 0.9734274585986482 1.0 1.0 2 Q12873 1 +Putative 5-3 exonuclease [IPR004859] 0.3856716417910529 0.0331395446362954 0.9735633079966896 1.0 1.0 2 Q8IZH2 1 +Xrn1, helical domain [IPR041412] 0.3856716417910529 0.0331395446362954 0.9735633079966896 1.0 1.0 2 Q8IZH2 1 +Polyamine biosynthesis domain [IPR030374] 0.3680597014925459 0.0321362998207217 0.9743633552799372 1.0 1.0 2 P19623 1 +Spermidine synthase, tetramerisation domain [IPR035246] 0.3680597014925459 0.0321362998207217 0.9743633552799372 1.0 1.0 2 P19623 1 +Serine-tRNA ligase catalytic core domain [IPR033729] 0.3617910447761271 0.0318706296390619 0.9745752208890572 1.0 1.0 2 P49591 1 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.292835820895528 0.0306796857522338 0.975524991957039 1.0 1.0 2 Q96CX2 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ed3f8acd8cd715df520f23688c47339424452014 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA lid domain [IPR041083]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMMECR1 domain [IPR002733]", "AMP-activated protein kinase, glycogen-binding domain [IPR032640]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATM, catalytic domain [IPR044107]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase [IPR006862]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adaptor protein ClpS, core [IPR003769]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Aftiphilin, clathrin-binding box [IPR029205]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha carbonic anhydrase domain [IPR001148]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Arrestin C-terminal-like domain [IPR011022]", "Arrestin-like, N-terminal [IPR011021]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Association with the SNF1 complex (ASC) domain [IPR006828]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAAT/Acyl-CoA thioester hydrolase C-terminal [IPR014940]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCL10, CARD domain [IPR042143]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Caspase recruitment domain [IPR031964]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cdc6, C-terminal [IPR015163]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA Ligase 4, adenylation domain [IPR044125]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase IV domain [IPR021536]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Death effector domain [IPR001875]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4706 [IPR031600]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-binding protein, first C-terminal SH3 domain [IPR035820]", "Dynamin-binding protein, first N-terminal SH3 domain [IPR035817]", "Dynamin-binding protein, second N-terminal SH3 domain [IPR035818]", "Dynamin-binding protein, third N-terminal SH3 domain [IPR035819]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF31, PUB domain [IPR040641]", "E3 ubiquitin-protein ligase RNF31, UBA-like domain [IPR032065]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FMP27, C-terminal [IPR019443]", "FMP27, GFWDK domain [IPR019441]", "FMP27, N-terminal [IPR019439]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focadhesin/RST, DUF3730 [IPR022542]", "Follistatin-like, N-terminal [IPR003645]", "Follistatin/Osteonectin EGF domain [IPR015369]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G protein-regulated inducer of neurite outgrowth, C-terminal [IPR032745]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GA-binding protein alpha subunit, N-terminal [IPR024668]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GATA-type transcription activator, N-terminal [IPR008013]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HEPN domain [IPR007842]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock factor (HSF)-type, DNA-binding [IPR000232]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IQ motif and SEC7 domain-containing protein, PH domain [IPR033742]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol 1,4,5-trisphosphate/ryanodine receptor [IPR014821]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intimal thickness related receptor, IRP [IPR019336]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transport domain [IPR005821]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KIND domain [IPR011019]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kazal domain [IPR002350]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "L27-2 [IPR015132]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Listerin, zinc finger, RING-type [IPR039804]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "LysM domain [IPR018392]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MALT1 immunoglobulin-like domain [IPR041077]", "MALT1, death domain [IPR037940]", "MAN1, RNA recognition motif [IPR034394]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MGA, conserved domain [IPR032060]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR14, PH-GRAM domain [IPR039803]", "MTMR6, PH-GRAM domain [IPR035998]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Muskelin, N-terminal [IPR010565]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-end aminoacyl transferase, N-terminal [IPR007471]", "N-end rule aminoacyl transferase, C-terminal [IPR007472]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Opioid growth factor receptor (OGFr) conserved domain [IPR006757]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain [IPR019601]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PTHB1, C-terminal domain [IPR028074]", "PTHB1, N-terminal domain [IPR028073]", "PUA domain [IPR002478]", "PUB domain [IPR018997]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Par3/HAL, N-terminal [IPR021922]", "ParB/Sulfiredoxin [IPR003115]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome biogenesis factor 1, N-terminal, alpha/beta [IPR015343]", "Peroxisome biogenesis factor 1, N-terminal, psi beta-barrel fold [IPR015342]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, TIG domain 2 [IPR041362]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plexin-A1, Sema domain [IPR042744]", "Pointed domain [IPR003118]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly A polymerase, head domain [IPR002646]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain [IPR039558]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RIH domain [IPR000699]", "RII binding domain [IPR018459]", "RING finger and SPRY domain-containing protein 1, SPRY domain [IPR035774]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNF31, C-terminal [IPR041031]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Riboflavin kinase domain, bacterial/eukaryotic [IPR015865]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "RyR/IP3R Homology associated domain [IPR013662]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SBF1/SBF2 domain [IPR022096]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3BP4, SH3 domain [IPR035456]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD5, SET domain [IPR044422]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Selenoprotein F/M domain [IPR014912]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydrolase FSH [IPR005645]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TANK binding kinase 1, ubiquitin-like domain [IPR041087]", "TANK-binding kinase 1, coiled-coil domain 1 [IPR041309]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1 domain family member 23, C-terminal domain [IPR045799]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRBP2 , first double-stranded RNA binding domain [IPR044469]", "TRBP2 , second double-stranded RNA binding domain [IPR044470]", "TRBP2 , third double-stranded RNA binding domain [IPR044471]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomere-length maintenance and DNA damage repair [IPR021668]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Trimerisation motif [IPR015049]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UME domain [IPR012993]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 13D, UBA domain [IPR041969]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate heat shock transcription factor, C-terminal domain [IPR010542]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WASP family, EVH1 domain [IPR033927]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZN598/Hel2, RING finger [IPR041888]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZZ3, zinc finger, ZZ-type [IPR041981]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, HIT-type [IPR007529]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain [IPR032828]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMCX3", "ARMT1", "ARRB1", "ARSA", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS3", "BCKDHB", "BCL10", "BCOR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf198", "C1orf35", "C2CD5", "CA8", "CACUL1", "CACYBP", "CAD", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD47", "CDC23", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNPY2", "COA3", "COASY", "COG2", "COIL", "COLEC12", "COMMD10", "COMMD7", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCTN1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERI1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM129B", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0391", "KIAA1671", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MEPCE", "METAP1", "METAP2", "METTL13", "MFN1", "MFN2", "MFSD10", "MGA", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH2", "NCBP1", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPN13", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAI1", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "RELA", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX1", "RIOX2", "RIPK1", "RNASEH2A", "RNASEH2B", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RSPRY1", "RTCA", "RTFDC1", "RTN2", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A2", "SLC27A4", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD5", "SNAP23", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1L", "SPEN", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLCD1", "TLE4", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTC7B", "TTF2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WDR47", "WFS1", "WNK1", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a5f1b7a28695dd3a998cd75b1703dc3588e0e6be99769ad698e3a8a55503e6d1 +size 253698 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..26b2c4bec7b1d4bd05bb0f68a5b69ee215c343de --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Proteasome, subunit alpha/beta [IPR001353] 10 14 2.2808392855415582 0.0225579587501973 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 0.0713092569444504 0.0096613748096581 0.0553069748090555 6.703246650942136e-05 +Proteasome B-type subunit [IPR023333] 4 7 2.070979650175905 0.0383606978193356 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 0.0816476539699214 0.1966693812600725 0.0005688349419973 +Importin subunit alpha [IPR024931] 0 5 2.0552721386820574 0.0398527268110915 1.900485436893204 4.162621359223301 -0.0859723492776628 0.5961263336607893 1.2157141643493203 0.6792778306365289 0.8334835296312452 0.3002751483750439 1.0 1.0 0.1358171161885085 0.2581989334031505 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..acd01a4a3768691ae81f2225b7ca97b1a7a887ef --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 2568, + "title": "Average number of proteins per term", + "value": 1.2834890965732086 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..56120177c8bf0fd38641650eaafcbcf52b9524f2 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ae050423054c4e050aa33703130b05a2beaf520d --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,122 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome, subunit alpha/beta [IPR001353] 0.659444372567592 2.2808392855415582 0.0225579587501973 1.0 0.2787317694494929 14 P60900,O14818,P28066,P49720,P20618,P28074,P25786,P25787,P28070,P49721 10 +Peptidase C14 family [IPR002398] 0.8473715651134954 2.198746487402937 0.0278959534446994 1.0 0.2787317694494929 4 P55212,P42574,Q14790 3 +Proteasome B-type subunit [IPR023333] 0.7104986127137164 2.070979650175905 0.0383606978193356 1.0 0.2787317694494929 7 P28074,P28070,P49721,P49720 4 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.7495328962056594 1.9471976434165463 0.0515110441208395 1.0 0.2894537446440172 5 P09960,P55786 2 +ThiF/MoeB/HesA family [IPR045886] 0.682511210762338 1.937479820025199 0.0526867178213308 1.0 0.2915937313904689 7 Q8TBC4,Q9UBT2,A0AVT1,P22314,Q13564,O95352 6 +Proteasome alpha-type subunit [IPR023332] 0.6770740026826286 1.911346516776024 0.0559600649129063 1.0 0.2971415234829839 7 P60900,O14818,P28066,P25786,P25787 5 +DNA-directed DNA polymerase, family B [IPR006172] 0.9239063275631968 1.8746614082691997 0.0608393192473091 1.0 0.3027829760307888 3 P28340 1 +Tubulin [IPR000217] 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3206310628546495 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Beta tubulin [IPR002453] 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3206310628546495 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Cyclin [IPR039361] 0.8874290833084517 1.7357103961162972 0.0826150543584969 1.0 0.3383659642625519 3 P20248,O95067 2 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.5730108939582607 1.5200440518478873 0.1284999044896055 1.0 0.4148290517642717 8 P49368,Q99832,P50991,P40227,P17987,P48643 6 +Protein arginine N-methyltransferase [IPR025799] 0.6869772998805187 1.5064412166744214 0.1319539466875983 1.0 0.4170518110466901 4 O14744,Q99873,O60678 3 +Cullin [IPR045093] 0.6064008586020968 1.4517029119599465 0.1465842292949273 1.0 0.4370777913457436 6 Q13617,Q13618,Q13619,Q93034 4 +26S proteasome regulatory subunit P45-like [IPR005937] 0.5920502092050184 1.3831706007313782 0.1666125619319356 1.0 0.464257591289176 6 P62191,P43686,P62333,P35998,P62195 5 +Protein PRRC2 [IPR033184] 0.7888826629461005 1.3555577382172386 0.1752399261010258 1.0 0.4813006740400366 3 Q5JSZ5 1 +Clathrin adaptor, mu subunit [IPR001392] 0.7832833013467517 1.3338662554742216 0.1822476923515132 1.0 0.4910934669031333 3 Q9Y2T2 1 +ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161] 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.5021691954033785 3 P17858,P08237 2 +ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914] 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.5021691954033785 3 P17858,P08237 2 +ATP-dependent 6-phosphofructokinase [IPR022953] 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.5021691954033785 3 P17858,P08237 2 +La domain containing protein [IPR045180] 0.6065132954885105 1.297174919117771 0.1945710083435987 1.0 0.5021691954033785 5 Q92615,Q71RC2,Q6PKG0,P05455 4 +Septin [IPR016491] 0.5588762701733442 1.2244224959854697 0.2207928872566396 1.0 0.5374370942891473 6 Q9P0V9,Q16181,Q14141,Q9UHD8,Q15019 5 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7527620185129902 1.215760641770766 0.2240761158609405 1.0 0.5405191644740805 3 Q06787,P51114 2 +Microtubule associated protein 1 [IPR026074] 0.7509032583976307 1.2085812427734417 0.2268237662244079 1.0 0.544377038938579 3 P78559 1 +Chaperone DnaJ [IPR012724] 0.7396955810754009 1.165343105415718 0.2438801373124945 1.0 0.5663116424378403 3 P31689 1 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.7301034508729122 1.128422032583512 0.259141727229212 1.0 0.5814743002346036 3 Q9Y5Y2 1 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.7301034508729122 1.128422032583512 0.259141727229212 1.0 0.5814743002346036 3 Q9Y5Y2 1 +Kinesin-like protein [IPR027640] 0.4542575041288969 1.1170692893627248 0.2639647002400582 1.0 0.5894081610169093 11 Q96Q89,Q99661,Q15058,O60333 4 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.5940279079776373 1.0947952617222738 0.2736063427553663 1.0 0.6010445579091367 4 Q8TEA1,Q08J23 2 +Initiation factor 2B-related [IPR000649] 0.7152126180755647 1.0713056872493574 0.284032003456439 1.0 0.6113949579850254 3 P49770 1 +Ribose-phosphate pyrophosphokinase [IPR005946] 0.7148402508211387 1.069881056563748 0.2846728509229554 1.0 0.6114018558869735 3 P11908,O60256 2 +Initiation factor 4G [IPR045208] 0.7136458644371415 1.065312805571634 0.2867343997989895 1.0 0.6130260738569032 3 O43432,Q04637 2 +Importin beta family [IPR040122] 0.5539288915446775 1.0556390163109424 0.2911331684268614 1.0 0.6163478784172961 5 Q14974,O00410,Q92973,Q8TEX9 4 +DNA mismatch repair MutS family [IPR045076] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.6184900025001863 3 P20585,P52701 2 +14-3-3 protein [IPR000308] 0.4968568382531855 1.0227204740233795 0.3064400281565951 1.0 0.6341392393226476 7 P31946,P27348 2 +Dynamin [IPR022812] 0.7004895721675375 1.0151380167897437 0.3100400418736742 1.0 0.6384555223350323 3 O00429 1 +Ubiquitin/SUMO-activating enzyme E1 [IPR000011] 0.6816960286652682 0.9440131828829824 0.3451629116874026 1.0 0.6692545350870943 3 P22314,A0AVT1 2 +Peptidase S9A, prolyl oligopeptidase [IPR002470] 0.9044776119403012 0.9240490677465596 0.3554607693089031 1.0 0.679245390883639 2 P48147 1 +Dedicator of cytokinesis [IPR026791] 0.9002985074626868 0.9100729988855968 0.3627840131958484 1.0 0.6846018414601777 2 Q96N67 1 +Glutamyl/glutaminyl-tRNA synthetase [IPR000924] 0.6723616233013451 0.9089784685991878 0.3633614913980616 1.0 0.6846018414601777 3 P47897 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.6553167510579302 0.8456103879700296 0.3977701285992372 1.0 0.7148171380285803 3 Q92688 1 +Translation initiation factor IF- 2 [IPR015760] 0.8743283582089582 0.8242576731011066 0.4097931632890517 1.0 0.7276945774796015 2 P46199 1 +Peptidase M3A/M3B [IPR045090] 0.6467602269334016 0.8141388423268481 0.4155654162901436 1.0 0.7324447419581941 3 Q99797,P52888 2 +Glutathione Transferase family [IPR040079] 0.4164233288110251 0.8099863925165895 0.4179479965213004 1.0 0.7346272793064337 9 O00299,P28161,P26641 3 +Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015] 0.86776119402985 0.8028716489143956 0.4220489242433127 1.0 0.7388013888594596 2 P09960 1 +Oxysterol-binding protein [IPR000648] 0.4613954580566096 0.7660459873250592 0.4436489395376237 1.0 0.7514328903618906 6 P22059,Q96SU4,Q9BZF3 3 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.8516417910447771 0.750993157334658 0.452656773870518 1.0 0.7575444781647421 2 P31689 1 +Caspase-3/7 [IPR015471] 0.8468656716417907 0.7358019137016618 0.4618512564349419 1.0 0.7641971820392597 2 P42574 1 +HAD-superfamily hydrolase, subfamily IIA [IPR006357] 0.6198865332935226 0.7170846107153573 0.4733218908003704 1.0 0.7717400733811755 3 Q9H0R4,A6NDG6 2 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.8370149253731343 0.7047510036442463 0.4809652047096029 1.0 0.7783206254996341 2 P48735 1 +Gamma-tubulin complex component protein [IPR007259] 0.8325373134328388 0.6907680710753387 0.4897113036422458 1.0 0.7841351301491741 2 Q9BSJ2 1 +Ezrin/radixin/moesin [IPR011174] 0.6118244252015479 0.6885817270541305 0.491086523427058 1.0 0.7850813462099177 3 P35241,P15311 2 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.3978592312007796 0.6318928743939204 0.5274568798341317 1.0 0.8098761796689191 8 P36404,Q9Y6B6 2 +Intracellular chloride channel [IPR002946] 0.8089552238805977 0.6186039477414612 0.5361773005493653 1.0 0.8161845333792355 2 O00299 1 +Nucleoside diphosphate kinase [IPR001564] 0.8023880597014958 0.5989861469133185 0.5491821225229754 1.0 0.8218529665728442 2 P15531 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.5825619587936817 0.588033375281971 0.5565098910002371 1.0 0.8238780980540629 3 P28072,P28074 2 +Fructose-bisphosphate aldolase, class-I [IPR000741] 0.7982089552238816 0.5866189161788037 0.5574596754556114 1.0 0.8238780980540629 2 P09972 1 +XPG/Rad2 endonuclease [IPR006084] 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.8293054095110345 2 Q9UQ84 1 +Asparagine-tRNA ligase [IPR004522] 0.7877611940298521 0.5561161988792851 0.5781314219596767 1.0 0.8344127765337287 2 O43776 1 +Ubiquitin-activating enzyme E1 [IPR018075] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.8449712771448018 2 P22314 1 +Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971] 0.774626865671644 0.5186598008993106 0.6039979990825195 1.0 0.8466522170545361 2 P42695 1 +Microtubule-associated protein RP/EB [IPR027328] 0.7728358208955245 0.5136327346012515 0.6075087886601156 1.0 0.84787096156477 2 Q15555 1 +GDP dissociation inhibitor [IPR018203] 0.4501374774213141 0.4986145266010005 0.6180509694087621 1.0 0.8536240470234743 4 P24386 1 +Exportin-1/5 [IPR045065] 0.7591044776119462 0.4757694090206351 0.634238665906897 1.0 0.8584226399875734 2 Q9HAV4 1 +Inosine-5'-monophosphate dehydrogenase [IPR005990] 0.7561194029850766 0.4677021169333527 0.6399976270251462 1.0 0.8627206510192669 2 P20839 1 +Sirtuin family [IPR003000] 0.7492537313432872 0.449378486729705 0.6531586478045197 1.0 0.8714876283002908 2 Q96EB6 1 +Melanoma-associated antigen [IPR037445] 0.5365780830098551 0.4416600588173265 0.6587352164636227 1.0 0.8737787856332713 3 Q96MG7,Q9UNF1 2 +E3 ubiquitin ligase Bre1 [IPR013956] 0.74029850746269 0.4259773076372375 0.6701243814156568 1.0 0.8762115129711846 2 Q5VTR2 1 +Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852] 0.737014925373137 0.4175427599539981 0.6762814546362641 1.0 0.8762960604265254 2 Q86VP6 1 +Translation Initiation factor eIF- 4e [IPR001040] 0.7364179104477637 0.4160177804228269 0.6773969924784313 1.0 0.8762960604265254 2 P06730 1 +Profilin1/2/3, vertebrate [IPR005454] 0.734925373134331 0.412216966164904 0.6801804026918581 1.0 0.8781816360546463 2 P35080 1 +Profilin [IPR005455] 0.734925373134331 0.412216966164904 0.6801804026918581 1.0 0.8781816360546463 2 P35080 1 +ADF/Cofilin [IPR017904] 0.5210510600179235 0.3962211130567338 0.6919419172145105 1.0 0.8828545938660645 3 P60981,P23528 2 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.7283582089552301 0.3956933290633267 0.6923312773345087 1.0 0.8828545938660645 2 Q9Y487 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.7283582089552301 0.3956933290633267 0.6923312773345087 1.0 0.8828545938660645 2 Q9Y487 1 +Inorganic pyrophosphatase [IPR008162] 0.7238805970149282 0.3846173655916615 0.7005209262027423 1.0 0.8828545938660645 2 Q9H2U2 1 +Dynein 1 light intermediate chain [IPR008467] 0.7235820895522447 0.3838845359170171 0.7010640284153791 1.0 0.8828545938660645 2 O43237 1 +Dynein family light intermediate chain [IPR022780] 0.7235820895522447 0.3838845359170171 0.7010640284153791 1.0 0.8828545938660645 2 O43237 1 +Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661] 0.7140298507462719 0.3608084868595432 0.7182426179856931 1.0 0.8917672414087963 2 O60566 1 +DNA2/NAM7-like helicase [IPR045055] 0.4038277407318701 0.341210900513134 0.7329448177570461 1.0 0.8969277571686818 4 Q9HCE1,P42694 2 +AP complex subunit beta [IPR026739] 0.5007443726159533 0.340372939530669 0.7335756945547605 1.0 0.8969277571686818 3 O00203 1 +Protein phosphatase 2C family [IPR015655] 0.4034725683324822 0.3401112568082449 0.7337727448671485 1.0 0.8969277571686818 4 O15355 1 +NF-kappa-B/Dorsal [IPR000451] 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.8969277571686818 2 Q00653 1 +Plakin [IPR043197] 0.3776516283238739 0.3334149364681414 0.7388210898924545 1.0 0.8969277571686818 5 Q03001,Q9UPN3,P58107,P15924 4 +Nucleobindin [IPR040250] 0.6985074626865708 0.3249084930090873 0.74525032884342 1.0 0.8984989880140388 2 P80303 1 +Developmentally regulated GTP-binding protein [IPR045001] 0.6725373134328403 0.2695233565473214 0.7875269710646449 1.0 0.9179275242664436 2 Q9Y295 1 +Peptidase M20 [IPR002933] 0.6689552238806014 0.2623629204849295 0.7930416567993537 1.0 0.9188234080965454 2 Q8IYS1 1 +Dephospho-CoA kinase [IPR001977] 0.6674626865671696 0.2594144913072364 0.7953154498802835 1.0 0.9188234080965454 2 Q13057 1 +Arginine-tRNA ligase [IPR001278] 0.6656716417910493 0.2559037427578756 0.7980251645306089 1.0 0.9188234080965454 2 P54136 1 +Aminoacyl-tRNA synthetase, class Ic [IPR002305] 0.4659098580921513 0.2551548223467551 0.7986035229250348 1.0 0.9188234080965454 3 P54577 1 +E3 ubiquitin ligase RBR family [IPR031127] 0.6644776119403031 0.2535798763499812 0.7998201449183269 1.0 0.9193993429499836 2 O95376 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.6626865671641837 0.250119098336586 0.8024952469464777 1.0 0.920825645289792 2 Q96RQ1 1 +Glutathione S-transferase, Mu class [IPR003081] 0.6555223880597063 0.2365779804817168 0.812984204345031 1.0 0.9215949166927117 2 P28161 1 +Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312] 0.3644222615885078 0.2309891201158351 0.8173232543837052 1.0 0.9221756020317824 4 O43776 1 +Casein Kinase 2, subunit alpha [IPR045216] 0.6522388059701556 0.2305341485874412 0.8176767312407978 1.0 0.9221756020317824 2 P19784 1 +Structural maintenance of chromosomes protein [IPR024704] 0.3589976263370145 0.2177989740150762 0.8275857439935979 1.0 0.9230609717743332 4 Q9NTJ3 1 +Vacuolar protein sorting-associated protein 4 [IPR031255] 0.6397014925373187 0.2084066737659732 0.8349114458218534 1.0 0.9239353386071412 2 O75351 1 +UDPGP family [IPR002618] 0.6361194029850799 0.2023625787748647 0.8396332809764113 1.0 0.9243605504629347 2 Q16222 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.6358208955223934 0.2018645059021103 0.8400226509936317 1.0 0.9243605504629347 2 Q13310 1 +L-lactate dehydrogenase [IPR011304] 0.6322388059701547 0.1959549435302278 0.8446454320786476 1.0 0.9243605504629347 2 P00338 1 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.6125373134328418 0.1656776106389893 0.868410666646166 1.0 0.9261340043751856 2 P36404 1 +Adaptor protein complex AP-2, alpha subunit [IPR017104] 0.6104477611940359 0.1626871069409129 0.8707647989130745 1.0 0.926314831652351 2 O94973 1 +Ran binding protein RanBP1-like [IPR045255] 0.3264635603345232 0.149491689268216 0.8811656666861911 1.0 0.932315191278098 4 Q9H6Z4,P49792,P43487 3 +Transcriptional repressor NocA-like [IPR022129] 0.562985074626873 0.1059008146915636 0.9156610476738812 1.0 0.9485347198170744 2 Q9H7S9 1 +26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134] 0.5495522388059773 0.0935366485046832 0.9254772360080568 1.0 0.9579304885403828 2 Q9BT78 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.5289552238806052 0.0774805550515667 0.9382412595879284 1.0 0.966855358997512 2 P18085 1 +Histone deacetylase family [IPR000286] 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 0.9701013500304584 2 Q13547 1 +Histone deacetylase [IPR003084] 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 0.9701013500304584 2 Q13547 1 +NDRG [IPR004142] 0.5170149253731429 0.0696686817949444 0.9444573694988904 1.0 0.9709233486281628 2 Q92597 1 +Taxilin family [IPR026183] 0.5065671641791132 0.0636635655706233 0.9492381163312932 1.0 0.973476138017026 2 Q9NUQ3 1 +Ribonuclease CAF1 [IPR006941] 0.2693341295909159 0.0442493981362722 0.9647056065693048 1.0 0.986986317742912 3 Q9UIV1,Q96GM8 2 +Methionyl-tRNA synthetase [IPR014758] 0.4358208955223979 0.0392597817685146 0.968683271377639 1.0 0.986986317742912 2 P56192 1 +Ribosomal protein L37/S30 [IPR010793] 0.4149253731343367 0.0359678503884654 0.9713079940321084 1.0 0.986986317742912 2 Q9NP92 1 +Ribosomal protein S17/S11 [IPR000266] 0.3970149253731414 0.0340351605573324 0.9728491128638028 1.0 0.986986317742912 2 P62280 1 +Peroxiredoxin, AhpC-type [IPR024706] 0.3913432835820966 0.0335594706138203 0.973228441814141 1.0 0.986986317742912 2 P30041 1 +AP-1/2/4 complex subunit beta [IPR016342] 0.3901492537313517 0.0334666106594291 0.97330249174274 1.0 0.986986317742912 2 Q10567 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.3859701492537373 0.0331603414989688 0.9735467236159968 1.0 0.986986317742912 2 Q9H267 1 +5'-3' exoribonuclease [IPR027073] 0.3856716417910529 0.0331395446362954 0.9735633079966896 1.0 0.986986317742912 2 Q8IZH2 1 +Rab GDI protein [IPR000806] 0.3725373134328439 0.0323529762462358 0.9741905623568629 1.0 0.986986317742912 2 P50395 1 +NudC family [IPR037898] 0.3644776119403023 0.03197938853353 0.9744884880569382 1.0 0.986986317742912 2 Q9Y266 1 +Serine-tRNA ligase, type1 [IPR002317] 0.3617910447761271 0.0318706296390619 0.9745752208890572 1.0 0.986986317742912 2 P49591 1 +Pyridoxal phosphate-dependent decarboxylase [IPR002129] 0.2674626865671705 0.0306023876556358 0.9755866379691928 1.0 0.986986317742912 2 Q6P996 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..037a980c81edc0e4d3f8b48f04e6ecf3f0846cdb --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 protein sigma [IPR037435]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit beta [IPR039160]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMMECR1 [IPR023473]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit s, mitochondrial [IPR026063]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA thioesterase, long chain [IPR016662]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Arginine-tRNA-protein transferase 1, eukaryotic [IPR017137]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arrestin [IPR000698]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylacetamide deacetylase [IPR017157]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-ketoacyl synthase [IPR000794]", "Beta-lactamase HcpB-like [IPR040239]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CASP8-associated protein 2 [IPR039674]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carbonic anhydrase, alpha-class [IPR023561]", "Carbonic anhydrase-related protein VIII [IPR041877]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Caspase-6 [IPR037554]", "Caspase-8 [IPR033170]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein Cdc6/18 [IPR016314]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein I [IPR012485]", "Centrosomal protein of 170kDa [IPR026644]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1A [IPR029508]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cox20 [IPR022533]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit VIb [IPR003213]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase 4 [IPR029710]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 4 [IPR030612]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Domain of unknown function DUF4525 [IPR027833]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-binding protein [IPR035469]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain Tctex-1 like [IPR005334]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase CBX4 [IPR043531]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase RNF31-like [IPR026254]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enolase-phosphatase E1 [IPR023943]", "Enolase-phosphatase E1, eukaryotes [IPR027511]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Eukaryotic translation initiation factor SUI1 [IPR005874]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 3 [IPR028479]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FMP27 [IPR045167]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Focadhesin [IPR021392]", "Focadhesin/RST1 [IPR045163]", "Folate-sensitive fragile site protein Fra10Ac1 [IPR019129]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G protein-regulated inducer of neurite outgrowth [IPR026646]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GMP reductase [IPR005993]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI-anchor transamidase [IPR028361]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase family 18 [IPR026116]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-binding protein, beta subunit [IPR016346]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Heat shock transcription factor family [IPR027725]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Homeobox protein Hox-A10/abdominal-B-like [IPR046333]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IQ motif and SEC7 domain-containing protein 1 [IPR030737]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor [IPR000493]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 8 [IPR038751]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "K/Cl co-transporter 4 [IPR030354]", "K/Cl co-transporter [IPR000076]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Katanin p60 subunit A1 [IPR028596]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "L-type amino acid transporter [IPR004760]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain-containing protein 1 [IPR028734]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "MAX gene-associated protein [IPR037935]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonyl-CoA epimerase [IPR017515]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial protein C2orf69 [IPR018881]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdopterin biosynthesis MoaE [IPR003448]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Molybdopterin synthase catalytic subunit, eukaryotes [IPR028888]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Mth938 domain-containing protein [IPR034096]", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [IPR033540]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myotubularin-related protein 5 [IPR030574]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-cadherin [IPR030051]", "N-end rule aminoacyl transferase [IPR030700]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NEMP family [IPR019358]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural Wiskott-Aldrich syndrome protein [IPR030214]", "Neurochondrin [IPR008709]", "Neurofilament medium polypeptide [IPR027697]", "Neuroplastin [IPR027112]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor NF-kappa-B, p100 subunit [IPR030497]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "OPI10 family [IPR031318]", "ORC ubiquitin ligase 1 [IPR039209]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Opioid growth factor receptor [IPR039574]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Parathyroid hormone-responsive B1 [IPR026511]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome biogenesis factor 1 [IPR025653]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1 [IPR028608]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein BRICK1 [IPR033378]", "Protein C10 [IPR026317]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein KTI12/L-seryl-tRNA(Sec) kinase [IPR013641]", "Protein Kti12 [IPR045106]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG1 [IPR030693]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG9 [IPR039177]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein strawberry notch [IPR026741]", "Protein suppressor of sable-like [IPR045124]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA-binding protein 47 [IPR034442]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RISC-loading complex subunit TRBP2 [IPR028605]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Raftlin family [IPR028169]", "Ragulator complex protein LAMTOR5 [IPR024135]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Riboflavin kinase [IPR023468]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P protein subunit Rpp40 [IPR013893]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAFB-like transcription modulator [IPR034780]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3 domain-binding protein 4 [IPR035455]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Selenoprotein F/M [IPR039992]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase ATM/Tel1 [IPR015519]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfiredoxin [IPR016692]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TBC1 domain family member 23 [IPR039755]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPMT family [IPR008854]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor GATA [IPR039355]", "Transcription factor GATA-6 [IPR028437]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, GA-binding, alpha subunit [IPR016312]", "Transcription factor, T-box [IPR001699]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor NocA-like [IPR022129]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tti2 family [IPR018870]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-protein phosphatase non-receptor type 13 [IPR012153]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "Tyrosyl-DNA phosphodiesterase I [IPR010347]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0688 family [IPR031530]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar (H+)-ATPase G subunit [IPR005124]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat and coiled-coil-containing protein family [IPR028041]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat domain phosphoinositide-interacting protein 4 [IPR032910]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 47 [IPR040067]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 89 [IPR039328]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR44/Dgr2 [IPR040324]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "Xyloside xylosyltransferase 1 [IPR042465]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "ZZ-type zinc finger-containing protein 3 [IPR037830]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger HIT domain-containing protein 2 [IPR039646]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 638 [IPR033096]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-guanine transglycosylase [IPR004803]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1S1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAIAP2", "BANF1", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BROX", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf174", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "C5orf24", "C8orf33", "CA8", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWF19L1", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX29", "DIAPH1", "DIAPH2", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FOCAD", "FOXC1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GMFB", "GMPR2", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS2", "INTS3", "INTS5", "INTS8", "INTS9", "IPO4", "IPO5", "IQSEC1", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KATNA1", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LLGL1", "LLPH", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC47", "LRRFIP1", "LSG1", "LSM12", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MALT1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA15", "NAA25", "NAA35", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFB10", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NELFB", "NELFCD", "NELFE", "NEMP1", "NES", "NF1", "NFKB2", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NSA2", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "ODR4", "OGDH", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PATL1", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POLA1", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM39", "RBM45", "RBM47", "RBM5", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFK", "RFTN1", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBF1", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFN", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG5", "SMG9", "SMPD4", "SMS", "SMU1", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SRXN1", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARS", "TARS2", "TBC1D23", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP1", "TECR", "TEDC1", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP2", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC19", "TTC26", "TTC37", "TTC38", "TTI2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBR1", "UBR4", "UBR7", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDR11", "WDR12", "WDR18", "WDR33", "WDR4", "WDR41", "WDR44", "WDR45", "WDR46", "WDR47", "WDR73", "WDR74", "WDR82", "WDR89", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YEATS2", "YEATS4", "YIF1A", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZCCHC3", 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a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..893629c70803aad83c4cb2d312fe24e3bdd2f018 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +HECT, E3 ligase catalytic domain [IPR035983] 5 10 2.7710477128692377 0.0055876238499039 3.5364077669902914 8.95631067961165 -0.082655155531572 0.5172769027958292 2.244980314039549 2.0498718834184824 0.9922663464789628 0.3114818745947644 1.0 0.2182850433665622 0.1283849415189241 0.0074494564855197 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 18 39 2.599825122913314 0.0093271278277784 9.805825242718448 32.80339805825243 -0.1088315233449008 0.6119304422693201 6.02109278283909 5.726593398203311 0.9050821109811418 0.3248802556462882 0.3859195782313845 0.0763877592579958 0.0009319656992676 0.0001557499732073 +Nucleophile aminohydrolases, N-terminal [IPR029055] 13 18 2.3347886346001863 0.0195544652233436 6.097087378640777 17.820388349514563 1.118176330768516 0.343571999079937 2.960138290874742 0.7151426259133536 1.128434210928413 0.3328142150103464 0.1092078710908161 0.0228657680446322 0.0213395532455881 1.515921045849114e-05 +Protein kinase-like domain superfamily [IPR011009] 49 84 2.2364711798111525 0.0253209231043933 20.41990291262136 70.37378640776699 -0.1027148677914017 0.6421551859523025 9.026438620260558 14.97574389072516 0.8497696380066302 0.3174331396666366 0.8213126664846052 0.4538792732520355 0.6581937482567143 0.7046094671515515 +SH2 domain superfamily [IPR036860] 7 11 2.1612908792071663 0.0306728770344033 4.402912621359223 10.932038834951456 -0.4489407284200368 0.4885586404123503 2.413109676901015 2.225239753297809 0.9045812375002334 0.3024068390169775 1.0 1.0 0.7509862965841895 0.0570529296125973 +Caspase-like domain superfamily [IPR029030] 3 5 2.1210797942136623 0.0339150880240943 1.0429042904290429 2.254125412541254 -0.1822739771754456 0.4061856906844451 0.8796230895210494 1.190490848145931 1.5263000234628414 0.3357787389369007 1.0 0.0729118409275157 0.0146338936924203 0.0003286021100258 +Phosphoribosyltransferase-like [IPR029057] 6 7 2.0955738749623456 0.0361200087506714 4.381067961165049 7.220873786407767 -0.4849811622119724 0.4443743988875169 1.963979224289181 0.76783089612297 1.0082315012212997 0.314953278431846 1.0 1.0 0.2348471946143729 0.0140126286640228 +Zinc finger, CCCH-type superfamily [IPR036855] 3 10 2.0707906962082845 0.0383783600655589 3.3737864077669903 7.762135922330097 -0.3578892099929518 0.5281753020488218 1.9696957118034255 1.8867764931022375 0.8660386883151266 0.3087477101242184 1.0 0.0302041354108555 0.0316151554384263 0.0498364179528963 +Importin-alpha, importin-beta-binding domain superfamily [IPR036975] 0 5 2.0552721386820574 0.0398527268110915 1.900485436893204 4.162621359223301 -0.0859723492776628 0.5961263336607893 1.2157141643493203 0.6792778306365289 0.8334835296312452 0.3002751483750439 1.0 1.0 0.1358171161885085 0.2581989334031505 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8ac4c5c575ee781df6907ea7ce5b7d2d96e61cdc --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 997, + "title": "Average number of proteins per term", + "value": 5.0220661985957875 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a7de1d9819fbe58690ad221a5c18503bea7b15d7 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0357d379fc1d98e0a3fc385bb3aa3b75a9def039 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,200 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +HECT, E3 ligase catalytic domain [IPR035983] 0.7575491789353765 2.7710477128692377 0.0055876238499039 0.9962518134296298 0.3668388303939864 10 Q9UII4,Q9ULT8,O95071,Q05086,Q15386 5 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.5916302534908707 2.599825122913314 0.0093271278277784 0.9999124048712424 0.3668388303939864 39 Q8N1G2,Q9UBP6,Q9BV86,O60294,Q08J23,Q86W50,O14744,P26358,O60678,Q9BV44,Q7Z4G4,P49327,Q8NEC7,Q7L2J0,Q7Z2T5,Q99873,Q8TEA1,Q14353 18 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.6616859427222433 2.3347886346001863 0.0195544652233436 0.9999999971867874 0.3668388303939864 18 Q06203,P60900,O14818,P28066,Q06210,P49720,P20618,P08243,P28074,P25786,P25787,P28070,P49721 13 +DNA/RNA polymerase superfamily [IPR043502] 0.8774324587354752 2.3238128847347586 0.0201355248663923 0.9999999984421896 0.3668388303939864 4 P28340 1 +Protein kinase-like domain superfamily [IPR011009] 0.4106896576029216 2.2364711798111525 0.0253209231043933 0.9999999999921466 0.3668388303939864 84 P49761,Q00535,P33981,Q13177,P53350,P41240,Q8TD19,P52564,P68400,Q16539,Q99570,Q96KB5,O75116,Q16512,O96017,Q13546,O15111,O60566,P36507,P11802,O43318,Q13418,Q96SB4,O00443,P19784,P78362,Q8IV63,O43683,Q13555,Q13464,Q13043,O14965,P31751,P28482,P17612,Q16513,Q14012,Q13535,Q9Y4A5,P45985,Q13153,Q99986,Q9NYV4,Q9UHD2,P35790,Q9H2G2,Q00534,Q9HA64,P42356 49 +SH2 domain superfamily [IPR036860] 0.6399994169650896 2.1612908792071663 0.0306728770344033 0.9999999999999676 0.3668388303939864 11 O15357,P19174,P41240,P46109,Q06124,P40763,P22681 7 +Caspase-like domain superfamily [IPR029030] 0.7889972789729206 2.1210797942136623 0.0339150880240943 0.9999999999999988 0.3668388303939864 5 P55212,P42574,Q14790 3 +Phosphoribosyltransferase-like [IPR029057] 0.7156950672645785 2.0955738749623456 0.0361200087506714 1.0 0.3668388303939864 7 P11172,Q06203,P00492,P11908,P07741,O60256 6 +Zinc finger, CCCH-type superfamily [IPR036855] 0.6234717767264576 2.0707906962082845 0.0383783600655589 1.0 0.3668388303939864 10 Q9UPT8,Q6P158,Q8IWR0 3 +RmlC-like cupin domain superfamily [IPR011051] 0.8119169199112106 2.049164037160381 0.0404460773705523 1.0 0.3668388303939864 4 P34949 1 +START-like domain superfamily [IPR023393] 0.797232058130475 1.986572573423842 0.0469697830586592 1.0 0.3668388303939864 4 Q9NQZ5 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.7907093109138746 1.9586550839521149 0.0501531939464507 1.0 0.3668388303939864 4 Q9Y2T2,P48444 2 +PIN-like domain superfamily [IPR029060] 0.7501519634361447 1.949947597182221 0.0511823652234488 1.0 0.3668388303939864 5 Q96EK7,Q9UQ84 2 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.7495328962056594 1.9471976434165463 0.0515110441208395 1.0 0.3668388303939864 5 P09960,P55786 2 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.7495328962056594 1.9471976434165463 0.0515110441208395 1.0 0.3668388303939864 5 P09960,P55786 2 +Ubiquitin-activating enzyme [IPR035985] 0.682511210762338 1.937479820025199 0.0526867178213308 1.0 0.3668388303939864 7 Q8TBC4,Q9UBT2,A0AVT1,P22314,Q13564,O95352 6 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.6547454227226338 1.93636305594 0.0528232509156836 1.0 0.3668388303939864 8 P68371,P04350,Q9BUK6,P07437,Q9BUF5,Q13885 6 +Ubiquitin-conjugating enzyme/RWD-like [IPR016135] 0.5967235375634189 1.9249671540560984 0.0542334675569744 1.0 0.3668388303939864 12 Q9C0C9,Q9NR09,P68036,P49427,P61086,Q16763,Q7Z7E8 7 +Metal-dependent hydrolase [IPR032466] 0.6737407260229673 1.895294675221038 0.0580533732253765 1.0 0.3668388303939864 7 P00813,Q9BPU6 2 +Papain-like cysteine peptidase superfamily [IPR038765] 0.5663735858416419 1.8831417543641784 0.0596811599695903 1.0 0.3668388303939864 25 Q86UV5,Q9UPT9,O94966,Q96K76,P17655,Q14694,Q93008,P45974,Q96FW1,Q9Y4P1,P51784,Q96RU2,Q01804,P40818 14 +DNA polymerase family B, thumb domain [IPR042087] 0.9239063275631968 1.8746614082691997 0.0608393192473091 1.0 0.3668388303939864 3 P28340 1 +DNA polymerase, palm domain superfamily [IPR023211] 0.9239063275631968 1.8746614082691997 0.0608393192473091 1.0 0.3668388303939864 3 P28340 1 +Armadillo-like helical [IPR011989] 0.4146371659039455 1.8478531793669384 0.0646235853358643 1.0 0.3709369858686095 114 Q8TEX9,O00629,Q7Z460,P42695,Q99570,Q9UBF2,Q96HW7,Q9H3U1,Q9Y6D5,O14981,Q9Y376,Q8TF05,Q14008,O14980,Q8TCG1,Q14997,O75165,Q9BTW9,Q86VP6,O15397,Q9Y263,Q92973,Q9ULT8,Q9Y4B6,Q9UIA9,P55060,Q9Y5L0,Q08AM6,P50851,Q96P70,Q9HAV4,Q92616,Q8IUR7,Q7Z4Q2,Q7Z5K2,Q13535,P53618,Q96T76,O95373,P30154,O60610,Q5VYK3,O00203,P42858,O94822,Q14738,Q15021,Q9NPQ8,Q9Y613,Q9BPX3,Q13200 51 +Kelch-type beta propeller [IPR015915] 0.7509629979453195 1.787085999565078 0.0739235899501618 1.0 0.3857637995508035 4 Q8TBB5,Q9UL63 2 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3857637995508035 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Tubulin, C-terminal [IPR023123] 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3857637995508035 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3857637995508035 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +GroES-like superfamily [IPR011032] 0.5673089142736745 1.7618141802474905 0.0781006980963163 1.0 0.3932646262728658 10 Q8N8N7,Q00796,Q8N4Q0 3 +Sec7 domain superfamily [IPR035999] 0.8901099509845177 1.7459651992847187 0.0808169991823679 1.0 0.3988839019050537 3 Q9Y6D5 1 +Sec7, C-terminal domain superfamily [IPR023394] 0.8901099509845177 1.7459651992847187 0.0808169991823679 1.0 0.3988839019050537 3 Q9Y6D5 1 +Cullin homology domain superfamily [IPR036317] 0.6404841148262088 1.733921056040636 0.0829320912904783 1.0 0.4013752185272177 7 Q13619,Q13618,Q93034,Q13617,Q14999 5 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.5811175159733136 1.6938276278814792 0.0902980425214039 1.0 0.4246563603483006 9 Q13616,Q9UPT5,Q13619,Q9UID3,Q13618,Q93034,Q13617 7 +Galactose-binding-like domain superfamily [IPR008979] 0.5495128710485557 1.6598328059041496 0.0969480920951202 1.0 0.4433818707286003 11 Q9UL63,O43396,Q14999 3 +Cyclin-like superfamily [IPR036915] 0.669863889041874 1.5880517146502922 0.11227464558144 1.0 0.4804198353849603 5 P20248,O95067 2 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.3558701225411279 1.5403166551303853 0.1234831859470002 1.0 0.5129697349548302 87 O75153,O00170,Q7L5D6,Q15008,Q9H0B6,Q9BQ70,Q99614,O15091,O76094,Q9BXJ9,Q99615,Q9H3U1,Q14CX7,Q96TC7,Q9Y5A7,Q9UPR3,Q8IWR0,Q5R3I4,Q9Y262,Q9UJX4,P61201,Q13535,O95801,Q15785,Q15020,Q32P28,P13674 27 +SUI1 domain superfamily [IPR036877] 0.8351976159939574 1.5348166214314023 0.1248288787861264 1.0 0.516025566340928 3 P41567 1 +Ribosomal protein L2, domain 2 [IPR014722] 0.517411429601049 1.475047583797866 0.1401997509951744 1.0 0.5335429390597995 12 Q92917,P62917,P61254,P62701,P63241,Q14999 6 +Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041] 0.5632077624239632 1.469379997500436 0.1417297495902123 1.0 0.5352445467478852 8 O94973,O43747,Q9Y678,Q10567,Q9UJY4,Q9UBF2 6 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.6082610359304451 1.4605744190562486 0.144132270763059 1.0 0.5386943101303336 6 Q8TC07,O60343,Q9Y3P9 3 +Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008] 0.6081964078310158 1.4602662483536326 0.1442169142982829 1.0 0.5386943101303336 6 P26640,Q9P2J5 2 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.6747311827956942 1.4522739982391095 0.1464254343483655 1.0 0.5386943101303336 4 Q15436,O95487,P53992 3 +Gelsolin-like domain superfamily [IPR036180] 0.6747311827956942 1.4522739982391095 0.1464254343483655 1.0 0.5386943101303336 4 Q15436,O95487,P53992 3 +NADP-dependent oxidoreductase domain superfamily [IPR036812] 0.6669224230040743 1.4176864033354415 0.1562823414497121 1.0 0.5440390475973947 4 O43488,P48507 2 +NagB/RpiA transferase-like [IPR037171] 0.5674836407166967 1.3734831048812128 0.169602209994049 1.0 0.5580640375051713 7 P49770,Q14232,O95336 3 +HSP40/DnaJ peptide-binding [IPR008971] 0.6197438312667938 1.3581063163317844 0.1744299512651739 1.0 0.5664712098090501 5 P31689 1 +Rhodanese-like domain superfamily [IPR036873] 0.5840685006439812 1.3449985967285096 0.1786256877347445 1.0 0.5747853207808306 6 Q99956,P40818 2 +PurM-like, C-terminal domain superfamily [IPR036676] 0.7860819772701744 1.3447078200782652 0.178719608266858 1.0 0.5747853207808306 3 P49903 1 +PurM-like, N-terminal domain superfamily [IPR036921] 0.7860819772701744 1.3447078200782652 0.178719608266858 1.0 0.5747853207808306 3 P49903 1 +Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449] 0.776649746192895 1.3081731424874603 0.1908145894086095 1.0 0.5937348618844527 3 P22314,Q9UBT2 2 +Phosphofructokinase superfamily [IPR035966] 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.5962596403623875 3 P17858,P08237 2 +PH-like domain superfamily [IPR011993] 0.3017428522442763 1.2699564942763006 0.2041001276505905 1.0 0.6092449918192776 62 Q8NC96,Q9BZF3,O75116,Q9NVZ3,Q86X55,O60333,O15020,O00401,Q9H4L5,O60343,P19174,Q96SU4,Q9Y3P9,P22059,Q96AC1,P35241,Q96TA1,Q92974,P21359,Q13464,P31751,Q9Y5B9,Q14155,P50851,Q9Y490,Q15036,P50570,P43487,Q9H8V3,O14654,P15311,Q13614 32 +TGS-like [IPR012676] 0.5636848416996695 1.247436028819971 0.2122376627987972 1.0 0.6241915923610643 6 P26639,Q9NTK5 2 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.4769079941553431 1.2397456910421911 0.2150694713950494 1.0 0.6283901246309409 17 O00299,Q9Y696,Q13505,P21266,P26640,P07814,Q8NEC7,P78417,P28161,P26641 10 +Formin, FH2 domain superfamily [IPR042201] 0.625805390123335 1.2353187736006357 0.2167118894391095 1.0 0.6283901246309409 4 Q9Y613 1 +Nucleic acid-binding, OB-fold [IPR012340] 0.387782879022841 1.2314350464083217 0.2181601959972434 1.0 0.6304513490123238 44 Q9Y2L1,P35244,P62917,Q9Y2V2,O43776,P25205,O60942,P67809,P18858 9 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.4672849827871427 1.2198906887901315 0.2225063160426807 1.0 0.6393048907623998 23 Q00653,O00221,Q8IWZ3,Q6W2J9,P42771,O75179,Q9H6S0,O15084 8 +CAP Gly-rich domain superfamily [IPR036859] 0.7473872797849909 1.195007033159566 0.2320842822407192 1.0 0.6525024258909173 3 Q15813,Q99426 2 +SMAD/FHA domain superfamily [IPR008984] 0.4638087857664553 1.166846499680835 0.2432723647050485 1.0 0.6661602654809784 12 Q5SW79,P85037,Q15058,O60333 4 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.7396955810754009 1.165343105415718 0.2438801373124945 1.0 0.6661602654809784 3 P31689 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.5003573940585045 1.1434753954896557 0.2528412646015283 1.0 0.671153964006618 8 O60502 1 +F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276] 0.7323587175461005 1.1370947356840364 0.2554986843990452 1.0 0.671153964006618 3 P47755 1 +F-actin-capping protein subunit alpha/beta [IPR037282] 0.7323587175461005 1.1370947356840364 0.2554986843990452 1.0 0.671153964006618 3 P47755 1 +Beta-grasp domain superfamily [IPR012675] 0.5182177041442311 1.1283508137477238 0.2591717915170992 1.0 0.671153964006618 7 P26639,Q9NTK5 2 +Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080] 0.455860421901328 1.121325099701238 0.262149505338759 1.0 0.6753567359760795 12 P49589,P54136,P26640,Q9P2J5 4 +F-box-like domain superfamily [IPR036047] 0.7250554160588185 1.1090294960336615 0.2674174577600299 1.0 0.6762256142355954 3 Q13309 1 +TBP domain superfamily [IPR012295] 0.5344613410088496 1.1077734773483432 0.2679596572293401 1.0 0.6762256142355954 6 O94973,Q10567,Q9Y678,Q9UBF2 4 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.5344613410088496 1.1077734773483432 0.2679596572293401 1.0 0.6762256142355954 6 O94973,Q10567,Q9Y678,Q9UBF2 4 +UBA-like superfamily [IPR009060] 0.4506240436334783 1.1063128851955364 0.2685911165870569 1.0 0.6762256142355954 22 Q6P158,Q7Z6Z7,Q04323,P61086,Q96S82,Q14157,Q13501,Q96RU2,Q9Y5A7,P22681 10 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.4454553063703413 1.0734543841440842 0.283067294894255 1.0 0.6934554099376131 10 Q5PRF9,Q9Y3Z3,O15357 3 +Initiation factor 2B-like, C-terminal [IPR042529] 0.7152126180755647 1.0713056872493574 0.284032003456439 1.0 0.6940684006031119 3 P49770 1 +CRAL-TRIO lipid binding domain superfamily [IPR036865] 0.5555144658296028 1.0628799973513543 0.2878363751472632 1.0 0.6999338195654182 5 P21359 1 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.7034058347953609 3 P20585,P52701 2 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.7034058347953609 3 P20585,P52701 2 +MutS, connector domain superfamily [IPR036678] 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.7034058347953609 3 P20585,P52701 2 +S15/NS1, RNA-binding [IPR009068] 0.5467582910068722 1.0229484345057784 0.3063322272812896 1.0 0.72398272055006 5 P23381,P56192,P41250,P07814 4 +14-3-3 domain superfamily [IPR036815] 0.4968568382531855 1.0227204740233795 0.3064400281565951 1.0 0.72398272055006 7 P31946,P27348 2 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.6930426993132234 0.9868698101216808 0.323706465986312 1.0 0.7419203369847198 3 Q15436,O95487 2 +Dedicator of cytokinesis, C-terminal, lobe C [IPR043162] 0.9002985074626868 0.9100729988855968 0.3627840131958484 1.0 0.7957802334499866 2 Q96N67 1 +Dedicator of cytokinesis, C-terminal, lobe A [IPR043161] 0.9002985074626868 0.9100729988855968 0.3627840131958484 1.0 0.7957802334499866 2 Q96N67 1 +Histidine phosphatase superfamily [IPR029033] 0.4875713993386292 0.8864272662073955 0.3753873317851139 1.0 0.799553004519473 6 Q9NPH0 1 +R3H domain superfamily [IPR036867] 0.5441124697425685 0.8773839086281676 0.3802781503079275 1.0 0.799553004519473 4 P38935 1 +Translation protein SH3-like domain superfamily [IPR008991] 0.42386904633162 0.8486107889344355 0.3960979015483459 1.0 0.8109026855106793 9 P61254,P63241,P62917,P50914 4 +Translation initiation factor IF-2, domain 3 superfamily [IPR036925] 0.8743283582089582 0.8242576731011066 0.4097931632890517 1.0 0.8321054659861192 2 P46199 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.6467602269334016 0.8141388423268481 0.4155654162901436 1.0 0.8324707663058066 3 Q99797,P52888 2 +Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149] 0.5290868228979908 0.8133886953933366 0.4159952386481316 1.0 0.8324707663058066 4 Q9Y5B9,Q9NQW7 2 +SNF2-like, N-terminal domain superfamily [IPR038718] 0.4041427199898629 0.8133053976450506 0.4160429831280119 1.0 0.8324707663058066 18 Q86WJ1,Q9H4L7,O14646,Q9Y620,Q14527,O14981,Q2NKX8 7 +Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502] 0.86776119402985 0.8028716489143956 0.4220489242433127 1.0 0.8376065930588461 2 P09960 1 +Creatinase/aminopeptidase-like [IPR036005] 0.4512337743339317 0.8014599775437065 0.4228654049415166 1.0 0.8376065930588461 7 P50579,Q9Y5B9,Q9UQ80,Q9NQW7 4 +MIT domain superfamily [IPR036181] 0.6398925052254393 0.7890639080290522 0.4300746552243941 1.0 0.8428543569487612 3 O75351,Q8N0X7 2 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 0.2663607808513902 0.7797340063128576 0.4355474579726084 1.0 0.8471101240054353 67 Q03164,Q9UPT9,Q96T51,Q9Y314,Q7Z3T8,O94822,Q14258,Q5VTR2,P19474,Q14527,P22681 11 +Armadillo-type fold [IPR016024] 0.3740682242406291 0.7774233691952961 0.436909029364837 1.0 0.8471101240054353 169 Q7Z460,Q7Z6Z7,Q99570,Q9Y6D5,Q14999,O14981,Q5VW36,Q86VP6,Q9Y263,Q9Y4B6,P55060,Q08AM6,Q96P70,Q9HAV4,Q13535,P53618,P30154,Q5VYK3,O94822,Q93008,P42356,Q9Y613,Q9BPX3,O00629,Q9UBF2,Q8TF05,Q8TCG1,Q14997,Q9BTW9,P21359,O15397,Q5H9R7,Q13144,Q9Y5L0,Q9HCG8,O95373,O60610,O00203,P42858,Q15021,Q9UBB6,Q9NPQ8,Q5T4S7,Q8TEX9,Q7Z3U7,Q96HW7,Q9H3U1,Q9Y376,Q14008,O14980,O75165,Q92973,Q9UIA9,Q6AI08,Q14185,Q04637,Q92616,Q7Z4Q2,Q7Z5K2,Q92538,O75155,P42695,Q92600,Q6PJG6,Q96QK1,P09960,O43432,O14617,Q9H4A4,Q9HAU5,O00443,P78344,Q9ULT8,P55010,P50851,Q86Y56,Q8IUR7,Q29RF7,Q96T76,Q9Y4A5,Q14738,Q13200 82 +PABC (PABP) domain [IPR036053] 0.6360107494774446 0.774969217349621 0.4383578493560134 1.0 0.8471101240054353 3 Q13310,O95071 2 +Oxysterol-binding protein superfamily [IPR037239] 0.4613954580566096 0.7660459873250592 0.4436489395376237 1.0 0.8498148422524597 6 P22059,Q96SU4,Q9BZF3 3 +AF1104-like superfamily [IPR036075] 0.8561194029850776 0.7653119830281717 0.4440857901840838 1.0 0.8498148422524597 2 Q9NVE7 1 +DUSP-like superfamily [IPR035927] 0.6316709980173856 0.7592819123692044 0.4476839351414199 1.0 0.8534242511204506 3 Q86UV5 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.4870082351350329 0.7563635851760224 0.4494312345660749 1.0 0.8551201161495738 5 Q9NUD5 1 +Rossmann-like alpha/beta/alpha sandwich fold [IPR014729] 0.3860615094794871 0.7524358270996746 0.4517890079944506 1.0 0.8563377204761736 27 Q13057,Q9P2J5,P49915,P26640,P07814,P49589,P47897,Q2VPK5,P08243,P41252,P54136,P54577 12 +HIT-like superfamily [IPR036265] 0.6270095605213082 0.7425182434318813 0.4577734026452635 1.0 0.8625508769388057 3 Q96C86 1 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 0.3874827496207903 0.7294881653956339 0.4657031044130488 1.0 0.8712786217976256 14 O95486,O95487,Q13045,P53992,Q14019,P60983,Q15436,Q9UJU6,Q6IBS0,P60981 10 +Anticodon-binding domain superfamily [IPR036621] 0.4807534926420913 0.7293479109488428 0.4657888720342371 1.0 0.8712786217976256 5 P26639,P07814 2 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.4337644315296222 0.7193945943615955 0.4718978265646212 1.0 0.8782385916074925 7 Q13535 1 +Aldolase-type TIM barrel [IPR013785] 0.3824583666689777 0.6953952543741945 0.4868076337635405 1.0 0.8784564267797181 16 Q9P2T1,P11172,P04075,P09972,Q9NR45,P20839,P43490,Q6P1R4 8 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.8325373134328388 0.6907680710753387 0.4897113036422458 1.0 0.8784564267797181 2 Q9BSJ2 1 +Moesin tail domain superfamily [IPR008954] 0.6118244252015479 0.6885817270541305 0.491086523427058 1.0 0.8784564267797181 3 P35241,P15311 2 +PUA-like superfamily [IPR015947] 0.3924426194124708 0.6883551399969607 0.491229166210011 1.0 0.8784564267797181 9 Q9ULC4,Q8TEA1,P41214 3 +Mitochondrial carrier domain superfamily [IPR023395] 0.3791555181970258 0.6762752422439805 0.4988659085437044 1.0 0.8793985696615322 21 Q70HW3 1 +GHMP kinase, C-terminal domain superfamily [IPR036554] 0.8179104477611944 0.6457022495833433 0.5184722034305786 1.0 0.8966672386781753 2 P53602 1 +SH3-like domain superfamily [IPR036028] 0.3516677891398584 0.6339266066046122 0.5261287207890999 1.0 0.8966672386781753 34 Q9UQB8,P19174,P41240,Q14185,Q14155,A1X283,Q92796 7 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151] 0.8050746268656763 0.6069848817139951 0.5438609452817147 1.0 0.9116821401632872 2 Q6P6C2 1 +Endonuclease/exonuclease/phosphatase superfamily [IPR036691] 0.4249753522771787 0.6053124749109934 0.5449713940749328 1.0 0.9116821401632872 6 Q01968,O15357,P27695 3 +Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001] 0.4508402657888765 0.6036977111907273 0.5460446361213835 1.0 0.9116821401632872 5 Q05639,O00178,Q9Y450 3 +Methylglyoxal synthase-like domain superfamily [IPR036914] 0.802985074626868 0.6007604046163129 0.5479995800840867 1.0 0.9116821401632872 2 P31939 1 +Nucleoside diphosphate kinase-like domain superfamily [IPR036850] 0.8023880597014958 0.5989861469133185 0.5491821225229754 1.0 0.9116821401632872 2 P15531 1 +5'-3' exonuclease, C-terminal domain superfamily [IPR036279] 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.9281033128479717 2 Q9UQ84 1 +Translation protein, beta-barrel domain superfamily [IPR009000] 0.359307080284763 0.5686798108876844 0.5695734512728785 1.0 0.9294021782636004 21 Q05639,Q9BTE6,O60841,P46199,Q9Y450,P39023,Q7Z2Z2,Q96HR8,P13639 9 +Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864] 0.3557926304788447 0.5562825867606896 0.5780176892024058 1.0 0.9401038109866208 16 Q96I59,O43776,P26639,P49591,P07814,P41250,Q9Y285,Q9NSD9 8 +Metallo-dependent phosphatase-like [IPR029052] 0.3804825446967733 0.5525996352889602 0.5805375917878599 1.0 0.9411316731910508 8 O00743,Q08209 2 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.7847761194029863 0.5475140528601696 0.5840256185946906 1.0 0.943717247550902 2 P35611 1 +HR1 repeat superfamily [IPR036274] 0.7820895522388105 0.5398164064803311 0.5893236514081743 1.0 0.9476704523450804 2 Q16512 1 +Nucleoside phosphorylase superfamily [IPR035994] 0.7800000000000056 0.5338587902352129 0.593439235364994 1.0 0.9481713424020816 2 Q13126 1 +Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.9498557730652 2 P22314 1 +Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.9498557730652 2 P22314 1 +Ubiquitin-activating enzyme E1, SCCH domain [IPR042063] 0.7764179104477626 0.523706629315184 0.6004826040208164 1.0 0.9498557730652 2 P22314 1 +EB1, C-terminal domain superfamily [IPR036133] 0.7728358208955245 0.5136327346012515 0.6075087886601156 1.0 0.9553011209853564 2 Q15555 1 +Prefoldin [IPR009053] 0.5494925245772782 0.4810974863985728 0.6304472144750402 1.0 0.9656018309134148 3 Q99471 1 +Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035] 0.7570149253731365 0.4701159914928866 0.6382721496265926 1.0 0.9700569103318794 2 P47897 1 +Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056] 0.7570149253731365 0.4701159914928866 0.6382721496265926 1.0 0.9700569103318794 2 P47897 1 +GYF-like domain superfamily [IPR035445] 0.7555223880597035 0.4660958915313023 0.6411468639503823 1.0 0.9710591426055728 2 Q6Y7W6 1 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.7501492537313472 0.4517499830146574 0.6514491058094207 1.0 0.975107609491894 2 Q9UBT2 1 +Sirtuin, catalytic core small domain superfamily [IPR026591] 0.7492537313432872 0.449378486729705 0.6531586478045197 1.0 0.975107609491894 2 Q96EB6 1 +MAGE homology domain, winged helix WH1 motif [IPR041898] 0.5365780830098551 0.4416600588173265 0.6587352164636227 1.0 0.9773199565687972 3 Q96MG7,Q9UNF1 2 +MAGE homology domain, winged helix WH2 motif [IPR041899] 0.5365780830098551 0.4416600588173265 0.6587352164636227 1.0 0.9773199565687972 3 Q96MG7,Q9UNF1 2 +PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946] 0.742388059701495 0.4313859317434088 0.6661877774134461 1.0 0.9777923030247516 2 P19174 1 +PX domain superfamily [IPR036871] 0.3239887413820372 0.4273086639970337 0.669154523105117 1.0 0.9777923030247516 12 Q53T59,Q9Y5X3,O60493,A1X283,O00443,Q15036 6 +Translation Initiation factor eIF- 4e-like [IPR023398] 0.7364179104477637 0.4160177804228269 0.6773969924784313 1.0 0.9777923030247516 2 P06730 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.3628065543212472 0.4147098710959013 0.6783543053257144 1.0 0.9777923030247516 7 O43847 1 +Profilin superfamily [IPR036140] 0.734925373134331 0.412216966164904 0.6801804026918581 1.0 0.9777923030247516 2 P35080 1 +Class I glutamine amidotransferase-like [IPR029062] 0.3597067251419042 0.4028618753504107 0.6870498392220261 1.0 0.9811770801618054 7 O15067,P27708,P17812 3 +Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091] 0.3428284395197039 0.3947049808299714 0.6930606264585606 1.0 0.9843040521071008 8 Q9UII4,Q8TD19,O95071,Q9P258 4 +Inorganic pyrophosphatase superfamily [IPR036649] 0.7238805970149282 0.3846173655916615 0.7005209262027423 1.0 0.9892625544251192 2 Q9H2U2 1 +Zinc finger, FYVE/PHD-type [IPR011011] 0.3139920324439983 0.3708819410208855 0.7107254663991653 1.0 0.9902784193604064 29 Q03164 1 +Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039] 0.7182089552238873 0.3708142333464149 0.710775899313735 1.0 0.9902784193604064 2 P35269 1 +p53-like transcription factor, DNA-binding [IPR008967] 0.349888064286883 0.36636895669208 0.7140897808117648 1.0 0.9902784193604064 7 P40763 1 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.714925373134335 0.3629406568098842 0.7166492148003658 1.0 0.9909837269846944 2 P42356 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.3310900072761223 0.3503150639217083 0.7261022612985462 1.0 0.9957688507766858 8 Q9H8V3,Q14155 2 +PPM-type phosphatase domain superfamily [IPR036457] 0.4034725683324821 0.3401112568082446 0.7337727448671487 1.0 0.9972245835663268 4 O15355 1 +Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059] 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.9972245835663268 2 Q00653 1 +Plakin repeat superfamily [IPR035915] 0.3776516283238739 0.3334149364681414 0.7388210898924545 1.0 0.9972245835663268 5 Q03001,Q9UPN3,P58107,P15924 4 +EF-hand domain pair [IPR011992] 0.254048479742233 0.3309951229491612 0.7406481694435036 1.0 0.9972245835663268 48 Q9H4M9,P19174,P17655,Q14257,Q96D71,Q96AY3,P22681 7 +Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882] 0.6886567164179145 0.303193768441742 0.761742197714449 1.0 1.0 2 Q9H1B7 1 +Death-like domain superfamily [IPR011029] 0.3006267420576889 0.2924576769684924 0.7699367148660541 1.0 1.0 9 Q14790 1 +Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900] 0.3845266959074082 0.2841634045105543 0.7762851588851052 1.0 1.0 4 O95394 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055] 0.3845266959074082 0.2841634045105543 0.7762851588851052 1.0 1.0 4 O95394 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.6776119402985146 0.2798693688715468 0.7795777285666874 1.0 1.0 2 Q13432 1 +Kinesin motor domain superfamily [IPR036961] 0.2896426177490377 0.2569576036272035 0.79721150177346 1.0 1.0 22 O60333,Q15058,Q92614,P33176,Q96Q89,P52732,Q99661 7 +Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695] 0.6656716417910493 0.2559037427578756 0.7980251645306089 1.0 1.0 2 P54136 1 +Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163] 0.3272564255827767 0.2477939217919982 0.8042938580059436 1.0 1.0 6 Q9BTE6,P26639,Q9BW92,Q5JTZ9,P49588 5 +Arrestin-like, C-terminal [IPR014752] 0.655820895522393 0.2371325021235537 0.8125539983001395 1.0 1.0 2 P49407 1 +Carnitine o-acyltransferase, N-terminal [IPR042572] 0.6483582089552289 0.2235240122968475 0.8231276967290573 1.0 1.0 2 Q9UKG9 1 +BRO1 domain superfamily [IPR038499] 0.6444776119403044 0.2166581276177326 0.8284747821842946 1.0 1.0 2 Q5VW32 1 +C2 domain superfamily [IPR035892] 0.2763229938686729 0.2159101335962634 0.8290577979321891 1.0 1.0 20 Q96N67,Q96PE3,P19174,Q14185,Q8N3C0,Q16512 6 +K Homology domain, type 1 superfamily [IPR036612] 0.2735029424913579 0.2050308615509138 0.8375480131590667 1.0 1.0 27 Q8IWZ3,P51114,Q96PU8,Q96AE4,O75179,Q06787,P51116 7 +Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616] 0.6328358208955277 0.1969312364191351 0.8438813491735062 1.0 1.0 2 Q9UGN5 1 +WGR domain superfamily [IPR036930] 0.6328358208955277 0.1969312364191351 0.8438813491735062 1.0 1.0 2 Q9UGN5 1 +Actin-crosslinking [IPR008999] 0.6310447761194085 0.1940127254930247 0.846165917722596 1.0 1.0 2 Q14331 1 +CRIB domain superfamily [IPR036936] 0.3464475489743746 0.1892360368099341 0.8499078246015075 1.0 1.0 4 O00401,Q13153 2 +eRF1, domain 2 superfamily [IPR042226] 0.6241791044776177 0.1831134466311784 0.8547090052742488 1.0 1.0 2 P62495 1 +ESCRT assembly domain [IPR037202] 0.6232835820895579 0.1817255388220909 0.8557981225986069 1.0 1.0 2 Q9H9H4 1 +Ribonuclease H superfamily [IPR036397] 0.2570034707272102 0.1804972626387008 0.8567622032026614 1.0 1.0 14 P28340 1 +Chaperone J-domain superfamily [IPR036869] 0.2630676561523553 0.1803810314916001 0.856853444750318 1.0 1.0 19 O60884,O75937,Q99615,P31689,Q8WXX5 5 +Nucleotidyltransferase superfamily [IPR043519] 0.2750989259363392 0.1791397155910497 0.8578279978389833 1.0 1.0 8 Q5TAX3 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.2572511754965825 0.1676770861033938 0.8668373235839253 1.0 1.0 9 Q01844 1 +RNA-binding S4 domain superfamily [IPR036986] 0.3273596176821933 0.1511217948118808 0.8798796401706446 1.0 1.0 4 P62701,Q9Y2Z4,P46781 3 +Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068] 0.4057927739623794 0.1435169423119473 0.8858819317254754 1.0 1.0 3 Q9HC38,Q04760 2 +Ubiquitin-like domain superfamily [IPR029071] 0.2225251093693885 0.139618941623469 0.8889610739619749 1.0 1.0 45 Q86UV5,Q96K76,Q99426,Q04323,P46379,Q8NCF5,Q15813,Q96S82,P61960,Q9Y5A7 10 +CH domain superfamily [IPR036872] 0.2468978551020248 0.134774789051008 0.8927899393673053 1.0 1.0 25 O15020,Q99439,Q5VUJ6,Q15555,Q14155,Q15691 6 +Ribokinase-like [IPR029056] 0.3932464256048252 0.1261161837771307 0.8996399569563853 1.0 1.0 3 O00764 1 +Winged helix-like DNA-binding domain superfamily [IPR036388] 0.1938460025231184 0.1229650186563162 0.902134798763986 1.0 1.0 52 Q9BUI4,Q13619,Q6PKG0,Q93034,P35269,P46063,P05455,P85037,P50579,P46783,P39019,Q8N3C0,Q13617,Q14999 14 +Winged helix DNA-binding domain superfamily [IPR036390] 0.1964786739644415 0.1196026405957913 0.9047979278492884 1.0 1.0 51 P61201,Q13619,Q6PKG0,O43242,Q15008,Q93034,P35269,P05455,P85037,P50579,P39019,Q8IWV7,Q8N3C0,Q13617,Q9Y285 15 +Diaphanous, GTPase-binding domain superfamily [IPR044933] 0.5710447761194102 0.1140767217851722 0.9091769750690588 1.0 1.0 2 O60610 1 +TRAF-like [IPR008974] 0.5671641791044848 0.1100678738569565 0.9123555462654788 1.0 1.0 2 Q93009 1 +NTF2-like domain superfamily [IPR032710] 0.2512948581924252 0.1078102254954584 0.9141462313989654 1.0 1.0 7 Q13283,P61970 2 +SMCs flexible hinge superfamily [IPR036277] 0.280946201397268 0.106513660807659 0.9151748173089432 1.0 1.0 5 Q9NTJ3 1 +Ribonuclease H-like superfamily [IPR012337] 0.2229667161754431 0.1043157518002408 0.9169187779820032 1.0 1.0 17 P28340 1 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.5591044776119478 0.1021690830908398 0.9186224674284268 1.0 1.0 2 Q9NRV9 1 +ENTH/VHS [IPR008942] 0.2067752304743093 0.100482861688991 0.9199609883608044 1.0 1.0 10 Q9UJY4,Q14677 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.2223885076419798 0.096749132216533 0.9229256209458304 1.0 1.0 21 Q96CU9 1 +P-loop containing nucleoside triphosphate hydrolase [IPR027417] 0.1785173873635175 0.092948954695661 0.9259441138310212 1.0 1.0 306 Q05639,Q9Y295,P61221,P25205,Q6PL18,P18074,Q92614,Q96Q89,Q92796,Q9H6S0,O14981,O60333,Q7Z478,Q9H4L7,Q9NTK5,P38935,Q6P158,Q9BSD7,Q9Y6B6,P26196,O60841,P42694,O00429,P46199,P46063,Q92499,Q15382,Q92620,O60231,Q99661,Q9BW83,Q9NUL7,Q15126,Q15645,Q9Y5Y2,Q8IX18,O14646,P20585,P04183,P13639,Q13057,O43237,Q14240,Q7L014,P52701,Q7Z7L1,Q86WJ1,Q8NE71,P50570,Q9BZX2,Q9H4M9,P36404,P36915,Q15058,P17812,Q9Y450,A3KN83,Q9Y620,Q8N3Z3,Q8N3C0,Q15477,Q14204,Q8TCY9,Q14527 64 +GINS, helical bundle-like domain superfamily [IPR036224] 0.3389514895247348 0.0726708911403911 0.942068012789274 1.0 1.0 3 Q9BRT9 1 +Histone deacetylase domain superfamily [IPR037138] 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 1.0 2 Q13547 1 +Arp2/3 complex subunit 2/4 [IPR034666] 0.5089552238806059 0.064970694586502 0.9481973332724 1.0 1.0 2 O15144 1 +BRK domain superfamily [IPR037259] 0.3200955509107128 0.06136791371839 0.9510662053230644 1.0 1.0 3 Q9HCK8,Q9P2D1 2 +Zinc-binding ribosomal protein [IPR011332] 0.3186025679307194 0.0606070372443232 0.9516721689188984 1.0 1.0 3 P83881,P61513 2 +EF-G domain III/V-like [IPR035647] 0.2252763668957202 0.0526435906130314 0.95801588481606 1.0 1.0 5 Q15029,Q7Z2Z2,Q8N442,P13639 4 +Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037] 0.3901492537313517 0.0334666106594291 0.97330249174274 1.0 1.0 2 Q10567 1 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.3859701492537373 0.0331603414989688 0.9735467236159968 1.0 1.0 2 Q9H267 1 +Spermidine synthase, tetramerisation domain superfamily [IPR037163] 0.3680597014925459 0.0321362998207217 0.9743633552799372 1.0 1.0 2 P19623 1 +Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978] 0.3617910447761271 0.0318706296390619 0.9745752208890572 1.0 1.0 2 P49591 1 +Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103] 0.3617910447761271 0.0318706296390619 0.9745752208890572 1.0 1.0 2 P49591 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ecd264cfeee2bfa50520cc2321b317ce8db74f3a --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMMECR1 domain superfamily [IPR036071]", "AMMECR1, N-terminal [IPR027485]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ASC domain superfamily [IPR037256]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioester hydrolase/BAAT, N-terminal [IPR042490]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha carbonic anhydrase domain superfamily [IPR036398]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin, N-terminal [IPR014753]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit VIb superfamily [IPR036549]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kazal domain superfamily [IPR036058]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin biosynthesis MoaE subunit superfamily [IPR036563]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PUB-like domain superfamily [IPR036339]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "ParB/Sulfiredoxin superfamily [IPR036086]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin kinase domain superfamily [IPR023465]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "RyR/IP3 receptor binding core, RIH domain superfamily [IPR035910]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Selenoprotein F/M, thioredoxin-like domain superfamily [IPR038219]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "T-box superfamily [IPR036960]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Tctex-1-like superfamily [IPR038586]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "Wiscott-Aldrich syndrome protein, C-terminal [IPR011026]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "AMMECR1", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANKRD46", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP5S", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATR", "ATXN10", "AURKA", "B3GAT3", "BABAM1", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT2", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CERS2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOPC", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS4", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPR2", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTI12", "L2HGDH", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED16", "MED21", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OVCA2", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMS", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX4", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM14C", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASL", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR47", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFP91", "ZFR", "ZFYVE16", "ZNF280C", "ZNF281", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZZZ3"], "leading_proteins": ["AARS", "AARS2", "AARSD1", "ABCE1", "ABCF1", "ACP6", "ADA", "ADD1", "AIP", "AKR7A2", "AKT2", "ALDOA", "ALDOC", "ALKBH5", "ANAPC5", "ANKHD1", "ANKRD17", "ANKRD28", "AP1B1", "AP1G1", "AP2A2", "AP3B1", "AP3D1", "AP3M1", "APEX1", "APRT", "ARCN1", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARL2", "ARMC8", "ARPC2", "ARRB1", "ASCC3", "ASNS", "ATAD2", "ATG4B", "ATG7", "ATIC", "ATR", "AURKA", "BAG6", "BAIAP2", "BCOR", "BIRC6", "BRAT1", "BROX", "BTAF1", "BUB1", "BUB1B", "CAB39", "CAD", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAPN2", "CAPZA2", "CARHSP1", "CARM1", "CARS", "CASP3", "CASP6", "CASP8", "CBL", "CCNA2", "CCNB2", "CDC34", "CDK12", "CDK4", "CDK5", "CDK6", "CDKN2A", "CEP170", "CHD1", "CHD1L", "CHD7", "CHD8", "CHEK2", "CHKA", "CHUK", "CIP2A", "CKAP5", "CLASP1", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLUH", "CMTR1", "CNN2", "CNOT9", "COASY", "COPB1", "COPG1", "COPG2", "COPS2", "COTL1", "CRKL", "CROT", "CSE1L", "CSK", "CSNK2A1", "CSNK2A2", "CTPS1", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL5", "CUL7", "CWC22", "DBNL", "DCAF1", "DCPS", "DDX1", "DDX28", "DDX46", "DDX6", "DHX16", "DHX29", "DHX38", "DHX40", "DHX57", "DIAPH1", "DIS3", "DLG3", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJC13", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DPYSL5", "DRG1", "DSP", "DST", "DSTN", "DUS1L", "DUSP9", "DYNC1H1", "DYNC1LI2", "ECT2", "EEF1A2", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHD1", "EIF1", "EIF2B1", "EIF2B2", "EIF2B5", "EIF2D", "EIF3L", "EIF4A2", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EPPK1", "EPRS", "ERCC2", "ERCC6L", "ETF1", "EWSR1", "EXO1", "EXOC7", "EZR", "FAM120B", "FAM129B", "FARSA", "FARSB", "FASN", "FERMT2", "FHOD1", "FKBP10", "FLII", "FMR1", "FN3KRP", "FOCAD", "FOXK1", "FOXRED1", "FRG1", "FUBP1", "FXR1", "FXR2", "G3BP1", "GAMT", "GARS", "GBF1", "GCLM", "GCN1", "GET4", "GFPT1", "GGA2", "GIGYF2", "GINS4", "GLO1", "GLOD4", "GMFB", "GMPR2", "GMPS", "GNL1", "GPKOW", "GSTCD", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTPBP1", "GTPBP8", "GUF1", "HBS1L", "HDAC1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELZ", "HERC5", "HLTF", "HPRT1", "HS1BP3", "HTT", "HUWE1", "IARS", "IFT27", "IGHMBP2", "ILK", "IMPDH1", "INPP4A", "INPPL1", "INTS4", "IPO4", "IPO7", "IPO8", "IPO9", "IRF2BPL", "IRS4", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF1B", "KIF20B", "KIF2C", "KIF5B", "KLC2", "KLHDC4", "KMT2A", "KPNA4", "LARP1", "LARS", "LCMT2", "LIG1", "LRBA", "LRCH2", "LTA4H", "LTN1", "MACF1", "MAGED2", "MAP2K2", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARS", "MCM3", "MCTS1", "MEPCE", "METAP2", "METTL1", "METTL16", "MGEA5", "MIPEP", "MKLN1", "MMS19", "MON2", "MPI", "MSH3", "MSH6", "MSTO1", "MTAP", "MTIF2", "MTMR2", "MTX1", "MVD", "MYO18A", "NAA15", "NAA25", "NAE1", "NAF1", "NAMPT", "NANS", "NARS", "NARS2", "NCAPD2", "NCAPD3", "NCAPG", "NCDN", "NECAP1", "NECAP2", "NEK9", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NME1", "NOSIP", "NPEPPS", "NRDC", "NSMCE3", "NSUN2", "NSUN6", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUTF2", "OCRL", "OLA1", "OSBP", "OSBPL3", "OSBPL6", "OSBPL9", "OTUB1", "OTUD4", "P3H1", "P4HA1", "PA2G4", "PABPC4", "PAK1", "PAK2", "PANK4", "PARP2", "PBK", "PDS5A", "PDXK", "PFAS", "PFDN5", "PFKL", "PFKM", "PFN2", "PGLS", "PGM3", "PI4KA", "PIK3C2A", "PIK3R4", "PKN1", "PKN2", "PLAA", "PLCG1", "PLK1", "PMVK", "POLD1", "POLR3C", "PPA2", "PPAT", "PPM1G", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP6C", "PPP6R3", "PRKACA", "PRMT1", "PRMT3", "PRMT5", "PRPS2", "PRPSAP2", "PSMA1", "PSMA2", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMD2", "PSMD3", "PSMD6", "PSME4", "PTGR2", "PTPN11", "QARS", "QKI", "RABGAP1", "RAD54B", "RANBP1", "RARS", "RCC2", "RCN2", "RDX", "RECQL", "REPS1", "RHEB", "RIC8A", "RIPK1", "RMDN3", "RNF20", "RNGTT", "RNPEP", "ROCK1", "ROCK2", "RPA3", "RPL14", "RPL26", "RPL3", "RPL36A", "RPL37A", "RPL8", "RPS10", "RPS19", "RPS4X", "RPS9", "RUFY1", "SAMD4B", "SAMHD1", "SAR1B", "SARS", "SART3", "SBNO1", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEPHS1", "SH3PXD2B", "SIRT1", "SKIV2L", "SKP2", "SLC25A26", "SLFN11", "SLK", "SMARCAD1", "SMC4", "SMG5", "SNX17", "SNX3", "SNX5", "SORD", "SPART", "SPTBN2", "SQSTM1", "SRM", "SRP72", "SRPK1", "SRPK2", "SSB", "STARD7", "STAT3", "STK4", "SUPT16H", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBCB", "TBCD", "TBCE", "TBK1", "TCF25", "THOP1", "THUMPD3", "TK1", "TLN1", "TNPO1", "TNPO3", "TOMM34", "TRIM21", "TRIM25", "TRIP13", "TRMT11", "TRMT1L", "TRRAP", "TTC1", "TTC38", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TWF2", "TXNL1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBL7", "UBR1", "UBR4", "UBR5", "UBXN1", "UCK2", "UFM1", "UMPS", "UNC119", "UNC45A", "UPF2", "URGCP", "USP10", "USP11", "USP19", "USP22", "USP28", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "VAC14", "VARS1", "VPS33B", "VPS35", "VPS37B", "VPS4B", "VPS51", "VRK1", "VRK3", "WAPL", "WARS", "WASL", "XPNPEP1", "XPO1", "XPO5", "XPO7", "YARS", "YARS2", "YBX1", "YTHDC2", "YWHAB", "YWHAQ", "ZADH2", "ZC3H4", "ZC3H7A", "ZCCHC11", "ZCCHC3", "ZFYVE16"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c5e5e4914741369b520cbb0014576754a2af15fe --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2dc633393876eeb241aaa6ca67441f7c5bd7488fc9d198aa08fbbd3ec426f828 +size 73824 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..88e8c8faf95f2887ce8e2a6e0abfe4547fe57b75 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1cf7683b537bdcbe6b7fa46b26d3de3f5e3869f5 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..911c0f98110fcfc0055bf4e7c9370c039a6363c6 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..64a0c6cd4eb371e391e1f54cf6236de0a684e67f --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "EIF5A", "FASN", "SLIT2"], "leading_proteins": []} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..853e1f39d36308f437330ce745e1db0ed21345b5 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "HEAT, type 2 [IPR021133]", "1": "Ankyrin repeat [IPR002110]", "2": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..910f6f9575058fef23118208432a50473d47a507 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae42e20fad81cb23ad3dd998191accb990da025bb96a146adfe8bda4061695ca +size 130497 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..898b392068d825960b87fc79531192f23ece42b8 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de79ebe29e2aa16b82e698fe21ae52074458b03c289b4c6abc9694e29b2ccefb +size 135573 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..48bdbc7f05fa96a4a240ced7064d5986f5aa8992 --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:452715cf98423db892049a52571848b2ad6e7541a89f08c93c4bfc838dc5f924 +size 165874 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3cc8b1fcf50b40889fbf4691c1b28f52cb493ce4 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0be75fa803b977b6bfe895371385e77c90aa9cf0fec3599c0dbfde0e54214be +size 75627 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..31565ec6d9578a6b7c2ce3399126107ad809f982 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Atypical Arm repeat [IPR032413] 0 5 2.0552721386820574 0.0398527268110915 1.900485436893204 4.162621359223301 -0.0859723492776628 0.5961263336607893 1.2157141643493203 0.6792778306365289 0.8334835296312452 0.3002751483750439 1.0 1.0 0.1358171161885085 0.2581989334031505 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..26fafe742afd27fc635e31cb2803a3b22d869caf --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 77, + "title": "Average number of proteins per term", + "value": 5.9480519480519485 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6de477f42dd040cd5ad2a7167132bf8f68179879 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..137520d5ddef78053265891008f2648a08b6bac4 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,15 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +HEAT, type 2 [IPR021133] 0.5824258489964053 1.8464598670958388 0.0648254614781009 0.994262325597988 0.6710894789558859 13 Q8TF05,Q8TEX9,Q7Z460,P30154,Q99570,Q92616,Q13535 7 +HEAT repeat [IPR000357] 0.5822748677894336 1.447005756344997 0.1478953113642949 0.9999955541220752 0.772922720339805 7 P30154,Q8TF05,Q8TEX9,Q6PJG6 4 +Ankyrin repeat [IPR002110] 0.4481515067822977 1.083879722374977 0.278418131476045 0.999999999987754 0.9693091619395374 21 Q00653,O00221,Q8IWZ3,Q6W2J9,O75179,Q9H6S0,O15084 7 +Hexapeptide repeat [IPR001451] 0.8788059701492557 0.838916244225299 0.4015163115214726 1.0 0.9693091619395374 2 Q13144 1 +Mitochondrial substrate/solute carrier [IPR018108] 0.3791555181970258 0.6762752422439805 0.4988659085437044 1.0 0.9693091619395374 21 Q70HW3 1 +Tetratricopeptide repeat 1 [IPR001440] 0.3386047221329233 0.5086351347670437 0.6110079967854798 1.0 0.9693091619395374 10 Q15785 1 +Leucine rich repeat 4 [IPR025875] 0.5343189934418182 0.434910628433953 0.6636272995720109 1.0 0.9693091619395374 3 Q13045 1 +Plectin repeat [IPR001101] 0.3776516283238739 0.3334149364681414 0.7388210898924545 1.0 0.9693091619395374 5 Q03001,Q9UPN3,P58107,P15924 4 +Proteasome/cyclosome repeat [IPR002015] 0.6250746268656775 0.184509141060037 0.8536140567384016 1.0 0.9693091619395374 2 Q13200 1 +Regulator of chromosome condensation, RCC1 [IPR000408] 0.2751961694470703 0.1507412087909586 0.8801798647244885 1.0 0.9693091619395374 7 Q9UII4,Q8TD19,Q9P258 3 +Importin repeat 6 [IPR041389] 0.5534328358209031 0.0969497744061357 0.9227662806870758 1.0 0.9693091619395374 2 O00410 1 +Importin repeat 4 [IPR041653] 0.5534328358209031 0.0969497744061357 0.9227662806870758 1.0 0.9693091619395374 2 O00410 1 +Armadillo [IPR000225] 0.1896554499776979 0.0714711298083707 0.9430228008581318 1.0 0.9693091619395374 16 O00629 1 +Tetratricopeptide repeat [IPR019734] 0.1872099101947971 0.0700770910123086 0.9441323005904584 1.0 0.9693091619395374 46 O95801,O00170,Q9H0B6,Q15785,Q9UJX4,Q99614,O76094,Q9BXJ9,Q99615,P13674 10 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2eb3442964233933c76d73c4c2d8b13e4b847713 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "Opioid growth factor receptor repeat [IPR006770]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACBD6", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD28", "ANKRD46", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMC8", "ARMCX3", "ARPC1A", "ARVCF", "ASPH", "ATR", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC23", "CDC27", "CDC40", "CHAF1B", "CIAO1", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1A", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GNB1", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HERC5", "HTT", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "JUP", "KAT7", "KDELC1", "KDELC2", "KDM2A", "KIDINS220", "KLC1", "KLC2", "KLHDC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MKLN1", "MPDU1", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NFKB2", "NFKBIE", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NUP214", "NUP37", "NUP43", "NXF1", "OGFR", "OGT", "P4HA1", "P4HA2", "PAAF1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNA1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RBBP4", "RBBP5", "RBBP7", "RCC1", "RCC1L", "RCC2", "RNH1", "RPAP3", "RRP9", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SIN3B", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TLE4", "TMTC3", "TOMM34", "TOMM70", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR47", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIPI2", "WRAP53", "XAB2", "XIAP", "XPO1", "YTHDC2", "ZC3H7B"], "leading_proteins": ["AIP", "ANAPC5", "ANKHD1", "ANKRD17", "ANKRD28", "ATR", "BCOR", "BRAT1", "CLASP1", "DNAJC7", "DSP", "DST", "EIF2B5", "EPPK1", "FLII", "GCN1", "HERC5", "IPO4", "IPO5", "KLC2", "KPNA4", "MACF1", "NAA15", "NEK9", "NFKB2", "NFKBIE", "P4HA1", "PIK3R4", "PPP2R1B", "PPP4R1", "PSMD2", "RCC2", "SLC25A26", "SRP72", "TOMM34", "TTC1", "TTC4", "YTHDC2"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..edac267e5ee33c39d4a7b86917881595c80d8cd7 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein polyubiquitination", "1": "Protein polymerization", "2": "Cell cycle g1 s phase transition", "3": "Regulation of protein polymerization", "4": "Lymphocyte homeostasis", "5": "Peptidyl serine modification", "6": "Mismatch repair", "7": "Neuron death"} \ No newline at end of file diff --git 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b/msigdb_gobp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4e2b2d9657453ee672954da3610ce473917fca28b49090545dfc05333f84b9a +size 214038 diff --git a/msigdb_gobp/basic/idx2term.json b/msigdb_gobp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8310dad1602e96382d1b46f56752c0e71c6657f9 --- /dev/null +++ b/msigdb_gobp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein polyubiquitination", "1": "Protein polymerization", "2": "Cell cycle g1 s phase transition", "3": "Regulation of protein polymerization", "4": "Lymphocyte homeostasis", "5": "Peptidyl serine modification", "6": "Nucleotide salvage", "7": "Mismatch repair", "8": "Neuron death", "9": "Retrograde axonal transport", "10": "Barbed end actin filament capping", "11": "Muscle cell differentiation", "12": "Purine nucleoside monophosphate biosynthetic process", "13": "Purine containing compound salvage", "14": "Protein k48 linked ubiquitination", 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sha256:3d980cf8f643699352fb35b6e92d852af6581e7f37cdbc1959ed1886e3a4d9c8 +size 138752 diff --git a/msigdb_gobp/basic/plot_9.png b/msigdb_gobp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..7f62dea26dc3fe44d67c256907e61a015faffafc --- /dev/null +++ b/msigdb_gobp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66886e30bf8c0f695c40903d536338cf190e1a4c1849b3f96d3ada67e0be782c +size 138451 diff --git a/msigdb_gobp/consensus.joblib b/msigdb_gobp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6c357e4d0327c04e0f1351fed440084e00ad10b9 --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8eff32d4e50b5f0f8e4cce72dff6a578f0462d723cb6692344bb3d47c4d5a1e +size 271252 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d8c63a59a1e40c871cfd4eedb239449d768eca0c --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,107 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Protein polyubiquitination 20 54 2.999861131541684 0.002701027207602 12.611650485436892 49.88592233009709 0.2698122167105246 0.6118505816632617 6.467218320876326 7.957965776185411 0.9830885011877004 0.3433598945202875 0.6048570118117644 0.1180365514600679 0.2028496001602897 0.0167527929122959 +Protein polymerization 37 77 2.979822530379335 0.002884154250395 20.648058252427184 79.22815533980582 -0.0389331724937979 0.6564498315595959 10.341025897751436 7.507690781396995 0.884459978126196 0.3320308777285349 0.630101108238381 0.3247940285354556 0.1412822465211458 0.1539815019430851 +Tissue regeneration 1 7 2.8031190141479008 0.0050610989129142 2.237864077669903 5.939320388349515 0.0058255705017962 0.5074833040137664 1.523831177412142 1.1756871670759337 0.9998757083281912 0.3118745730683118 1.0 0.2890484038757667 0.2140290435859761 0.5274882304980407 +Cell cycle g1 s phase transition 30 63 2.801717511303908 0.0050831361925571 17.57281553398058 59.398058252427184 -0.1692726479028181 0.658765664317355 7.635636864413838 7.325430907270178 0.7692537416714049 0.302449460535411 0.2079589738626584 0.5198523317498815 0.0759377739179387 0.0341242917387946 +Skeletal muscle tissue regeneration 1 6 2.691601370500141 0.0071109884064615 1.8106796116504855 4.890776699029126 0.1338591162181891 0.5312746316853706 1.3285814481399312 1.1213776109113207 0.9530858361170068 0.3091765164809326 1.0 0.1880666528119386 0.0970188007029606 0.2898287915273368 +Regulation of protein polymerization 25 63 2.679733067496812 0.0073680889983771 15.08980582524272 61.50728155339806 -0.0207642183528564 0.65203344430875 8.472639744149449 5.267361066990573 0.8559732965794926 0.3312375746436992 0.5117524789249386 0.4271650672007623 0.1662528915351983 0.332349260732926 +Response to nerve growth factor 4 10 2.6422623208572618 0.0082354244357754 2.9199029126213594 10.737864077669904 -0.0308315673557383 0.4841739597751167 1.7928910293158438 2.4592254090654397 1.0413664452810265 0.3101617236543262 1.0 0.2544971315679337 0.00078365760665 0.0157766780310383 +Lymphocyte homeostasis 6 11 2.6415804098227578 0.0082520216309265 2.6140776699029127 9.157766990291265 0.5015073935560286 0.4550844260550281 1.7177248086463766 2.3424870328572864 0.9807186663047854 0.3016646201978763 1.0 1.0 0.0624604060693988 0.0093317531476842 +Glucan biosynthetic process 1 11 2.528027941869384 0.0114705222637314 3.2257281553398056 10.385922330097088 -0.4862804257042186 0.4295538797632117 1.7708585499046454 1.6052389574366306 1.0113489562146922 0.2866158719763215 0.1336282364993428 0.034177713847331 0.1702739325736192 0.4482773855235765 +Peptidyl serine modification 40 70 2.514187356224273 0.0119307033377769 15.684466019417476 64.47330097087378 -0.0255197168682743 0.675603190918526 7.744553454525985 10.538959887548597 0.7555498450856009 0.3087691688728917 0.2866521742877416 0.06571098959142 0.3163247498061844 0.2278217630809486 +Nucleotide salvage 5 7 2.511873274747541 0.0120092205031085 2.2815533980582523 5.953883495145631 0.203366659475343 0.4039201470736932 1.813741911870816 0.8759513363812925 1.1722588299831294 0.2998717312129536 1.0 1.0 0.0003603697136508 4.367834065541858e-05 +Mismatch repair 6 13 2.483978896471118 0.0129923507338511 3.6529126213592233 11.45873786407767 0.0828860718784932 0.4809581195583483 2.894322574821655 1.7364583863143002 1.0614594046311725 0.3054071718849208 0.0058319944063555 0.0016008508165985 0.0213395532455881 0.000136356004925 +Dna strand elongation involved in dna replication 3 12 2.454268486007256 0.0141171534810404 4.885922330097087 12.240291262135925 -0.2237108593703924 0.5687735928999378 3.035245367440551 1.4014652223781012 0.851420489104331 0.3001091147858945 0.0755969254036216 0.0108829135912838 0.0006049883657283 0.0078812527225172 +Ribosome disassembly 3 6 2.4525790363994595 0.014183621655083 2.407766990291262 4.509708737864078 -0.5158076082871491 0.4403727277009044 1.368415519162625 1.1689356675104148 0.9793958110820656 0.3008640516151468 0.0362999537782941 0.0729118409275157 0.0007018811705627 0.0003286021100258 +Neuron death 30 81 2.4521929575965724 0.0141988498957181 14.20388349514563 73.25242718446601 0.8007457732231772 0.4829929240620625 5.370919943079612 7.537889337352574 0.9625497526284538 0.3667297831171348 0.0185084592748952 0.0047645711393512 0.0070793949674702 0.0111405681833955 +N terminal protein amino acid modification 4 8 2.4460407411674168 0.0144434678320268 2.45873786407767 8.439320388349515 0.5804938412353885 0.4249038973587519 1.7696871423418874 1.4824892226959214 1.0345977331938565 0.310740936912418 0.1133242047904145 0.2182850433665622 0.1283849415189241 0.0351238878380088 +Retrograde axonal transport 6 9 2.4391750543459216 0.0147208352623491 3.0898058252427183 8.951456310679612 -0.160267704010341 0.5433978483006399 1.8938308023493629 1.5352090447877251 0.9081817538614372 0.3039851939919125 1.0 1.0 1.0 0.0539281835546241 +Barbed end actin filament capping 7 11 2.4321903852379427 0.015007816378695 4.12621359223301 10.725728155339803 -0.1856016368827134 0.5970560528628625 2.5710472032556404 1.0357766205383665 0.7953154282593617 0.2919849813840544 1.0 1.0 1.0 1.0 +Muscle cell differentiation 13 67 2.3978431667828586 0.0164919247662829 13.58495145631068 61.83980582524272 0.1726021306033935 0.6436549160646058 5.702585578419399 5.973937567415945 0.8016706101837519 0.3164898778535634 0.2488676107873339 0.1326508932276218 0.1284327302013125 0.0812745083949147 +Purine nucleoside monophosphate biosynthetic process 12 16 2.374965846655814 0.0175505740371559 6.378640776699029 14.393203883495143 -0.2438790258920936 0.4480041000817844 4.080777826233024 1.0431247061623443 1.1715392352548326 0.3230740108250365 1.0 1.0 0.0014106533758772 3.3887188864580013e-06 +Positive regulation of calcium ion transport into cytosol 4 6 2.366473878862861 0.0179584414799061 2.4150485436893203 6.754854368932039 -0.1252435055298218 0.4951723805807685 1.6175814223208935 0.9682336676145236 0.993285888866281 0.3039119708047215 1.0 1.0 0.3547863423381785 0.0013369974246366 +Positive regulation of release of sequestered calcium ion into cytosol 4 6 2.366473878862861 0.0179584414799061 2.2985436893203883 6.393203883495145 -0.0768098245406624 0.505909583507104 1.550351609206413 0.9832344223557812 0.9755496629465316 0.3017713651491867 1.0 1.0 0.3058660732099017 0.0005289198821125 +Positive regulation of dendrite morphogenesis 1 10 2.366247249091851 0.0179694392795357 2.308252427184466 9.483009708737864 0.3203686362651967 0.5371764025687298 2.265106751673018 1.1500116799334736 0.8431428255248603 0.2929492883591474 0.0078008082024094 0.0302041354108555 0.1532325517723639 0.4145551447304083 +Purine containing compound salvage 6 8 2.360569761199538 0.018246886041664 1.8737864077669903 7.233009708737864 0.7743343410521683 0.3736672462346809 1.748395167894324 0.8238423298008908 1.0837559690437977 0.3116170205148165 1.0 0.1073692926764015 0.0001383364889708 9.139729707100432e-06 +Peptidyl lysine dimethylation 1 5 2.353502321663853 0.0185974917354276 1.866504854368932 5.116504854368932 -0.0989292420712661 0.5171849485260218 1.4326783992255565 1.865897170257899 0.9746070391550048 0.2967488361124668 0.0967463289884207 0.0179304062363867 0.0970188007029606 0.2898287915273368 +Protein k48 linked ubiquitination 6 11 2.3457393223044702 0.0189893832485221 4.055825242718447 11.155339805825244 -0.0465840331509609 0.5637128886680042 2.4779199796947786 1.964526581738523 0.9309477767022024 0.3089866453102476 0.2356515416958359 0.1033866218184072 0.1627379716452803 0.1495389057689769 +Astrocyte differentiation 5 10 2.3436960592835137 0.0190937240244435 3.094660194174758 11.42233009708738 0.0584209125016935 0.5547337588992057 2.207285076469246 1.943694412377063 0.913626470884625 0.299483644308788 1.0 1.0 0.0624604060693988 0.0093317531476842 +T cell homeostasis 4 7 2.334592269604668 0.019564730777668 1.7111650485436891 5.427184466019417 0.3175576411827722 0.4948259111815926 1.3225349306017935 1.6106559102173 0.956519419315456 0.3032064248421641 1.0 1.0 0.4147125777305785 0.0200033311952484 +Dna dealkylation 5 8 2.333837693059254 0.0196042222867267 3.7305825242718447 7.439320388349515 -0.3455100653685099 0.4809796209240795 1.9676353780753744 1.0328147627936528 0.9439003459529144 0.2997425564658039 1.0 1.0 0.4147125777305785 0.088385561156941 +Imp biosynthetic process 6 9 2.3185582867872627 0.0204189990923917 5.084951456310679 8.298543689320388 -0.6789988981654033 0.4131022333902552 2.1372940762836774 0.4628927778864114 1.0131025604773731 0.3205046868007672 1.0 1.0 0.0014512760162947 2.2585304294532336e-06 +Imp metabolic process 8 12 2.318333081440312 0.0204312258414895 6.5 11.33980582524272 -0.7055458461402502 0.4231961532929048 2.9308370519772535 0.5961591964726218 1.0398182735064374 0.336121823181493 1.0 1.0 0.0060877577335729 6.703246650942136e-05 +Purine ribonucleotide salvage 4 6 2.317571319197953 0.0204726304437639 2.0533980582524274 4.936893203883495 0.2808165383528844 0.3980862538317732 1.6031107826209183 0.6725535011399171 1.16348345355908 0.2954242001144523 1.0 1.0 0.0004465916791071 5.11944457815466e-06 +Purine nucleotide salvage 4 6 2.317571319197953 0.0204726304437639 2.0679611650485437 5.128640776699029 0.2558101865939456 0.4027366561517723 1.6503140973314958 0.7730001426087728 1.1650486447499997 0.2988088626042584 1.0 1.0 0.0010341818226167 2.8311070051942505e-05 +Base excision repair 9 17 2.294119781883503 0.0217836193801548 7.453883495145631 19.182038834951456 -0.3247537719984735 0.5062328031987017 3.968359014502092 2.8152441682112026 1.0683653259818937 0.3257311906495272 0.1880892294635792 0.0668951919761703 0.0224343496689777 0.0055591316089767 +Glycosyl compound biosynthetic process 5 8 2.2819496407406654 0.0224923135978314 1.7621359223300972 6.927184466019417 0.7674599123201137 0.3848892158216302 1.5816678247150102 0.68587612099484 1.0539983320068638 0.3161304697180149 1.0 0.1486636480545473 0.0072626368836444 0.0010053263520343 +Trna methylation 9 16 2.278158124913185 0.0227171581941554 4.684466019417476 13.0 -0.1667695682670125 0.6113608461571705 2.924196256066093 3.1127673199822556 0.7950142109767884 0.2904828311985307 1.0 0.3155444220122531 0.0025462469777919 0.0028137185393519 +Microtubule polymerization or depolymerization 26 43 2.2768976217667354 0.0227923399475475 13.53640776699029 40.94174757281554 -0.315346847705747 0.6178667072501902 6.30080397926982 4.916931797901264 0.8711699043308604 0.3245766892141421 1.0 0.2704847757544211 0.0456243342605336 0.0060200153588743 +Protein k63 linked ubiquitination 8 16 2.262566094636373 0.0236624501792679 4.781553398058253 14.62864077669903 0.021939769116928 0.5762133810650545 3.291774024402521 2.1385175649998738 0.9003387169486793 0.3130947703244208 1.0 0.3534667347825532 0.6741567840482483 0.0062896490617296 +Response to interferon beta 2 6 2.259552117423962 0.0238490622328204 1.7427184466019416 5.924757281553398 -0.0391027965460305 0.5935664076188614 1.413121721012591 1.09130219236852 0.7760035236459375 0.2792431283657119 0.0018270290105774 0.0074166479276302 0.0040998381065295 0.0277461310389573 +Cellular response to interferon beta 2 6 2.259552117423962 0.0238490622328204 1.7427184466019416 5.924757281553398 -0.0391027965460305 0.5935664076188614 1.413121721012591 1.09130219236852 0.7760035236459375 0.2792431283657119 0.0013329072658427 0.0054453582128303 0.0025675639060761 0.018020673376298 +Base excision repair gap filling 5 8 2.255566526303356 0.0240977915509863 4.691747572815534 9.300970873786408 -0.6287292395647202 0.4057853647795099 2.326426872810092 1.3225817019658803 1.0169666536153072 0.3179099055464128 1.0 0.1405588989726414 0.0060877577335729 0.0062633876942655 +Regulation of oligodendrocyte differentiation 2 8 2.250842024206177 0.0243955448071733 3.128640776699029 7.12621359223301 -0.2938351586700864 0.5753832518849439 1.9158143841337465 0.8146666677979875 0.7380648312849413 0.2813312234409597 1.0 0.1880666528119386 0.0970188007029606 0.088385561156941 +Gmp biosynthetic process 9 13 2.235109503931018 0.0254101605918979 5.487864077669903 12.216019417475728 -0.2136784453243963 0.4368939162536698 3.5317352236914625 0.6963397226438397 1.1565056526524748 0.3115850466790157 1.0 1.0 0.003279014583115 8.104989222609044e-07 +Regulation of peptidyl threonine phosphorylation 6 8 2.2328267797181125 0.0255603695717296 2.563106796116505 8.009708737864077 0.03818910591028 0.5293686155535875 1.8704129802666387 1.424440926820526 0.934047724902416 0.3020531226500109 1.0 1.0 1.0 0.7262550906181415 +Positive regulation of histone h3 k4 methylation 2 12 2.2284654126301997 0.025849495298631 4.577669902912621 11.898058252427184 -0.3265014707175765 0.5358235577350856 2.844904558906738 1.568592256295296 0.895928954894182 0.3088100681519299 0.1050728360238821 0.2033176172301104 0.0191106391622076 0.1083207684216986 +Regulation of chromatin binding 3 6 2.2208696188614714 0.0263597935109354 1.8592233009708736 5.327669902912621 0.1210590175529385 0.5573402276813765 1.4778583883972425 1.507879436788725 0.9170620056194704 0.3036684408697042 1.0 1.0 0.112413166150522 0.1083207684216986 +Nucleoside monophosphate biosynthetic process 18 26 2.217589000171013 0.0265828685810458 10.519417475728156 24.43446601941747 -0.46572953328444 0.4668532857531798 5.829046088464405 2.1940069422035915 1.2456954597659804 0.347724228093804 1.0 1.0 0.0028440426535884 1.908488484221945e-05 +Regulation of gluconeogenesis 0 11 2.2110269674421468 0.0270339696562202 3.004854368932039 10.138349514563108 -0.55489895678236 0.4413907224092362 1.934604580193124 1.041742935593512 0.9311546629337264 0.2831645320415113 0.1336282364993428 0.2544971315679337 0.5300461112646178 0.4482773855235765 +Histone h3 k14 acetylation 1 8 2.2053901040190063 0.0274267318679881 2.325242718446602 6.317961165048544 -0.1376874246008075 0.510561310048539 1.7239162035928792 1.871702334656825 0.93740382856974 0.2854471063817351 0.092554689717322 0.1803331870597798 0.4002719515071794 0.2715157705871365 +Fructose 1 6 bisphosphate metabolic process 4 6 2.1966676351409005 0.0280441919348444 3.6723300970873782 5.949029126213592 -0.7438000856362101 0.3619293147332825 1.575575532930095 0.2869728668988232 1.0646226311796825 0.3141355268048594 1.0 1.0 1.0 0.0309764532364539 +Ribonucleoside monophosphate biosynthetic process 16 22 2.192020712244334 0.0283780111053058 8.492718446601941 19.859223300970875 -0.3536937822657926 0.4733932871260397 5.243344869983477 1.8300584580404569 1.1780795453591573 0.3341638093822648 1.0 1.0 0.0010526716732067 2.2380734395490096e-06 +Amp biosynthetic process 8 12 2.179380914235348 0.0293033827701358 5.092233009708738 11.320388349514564 -0.2266022541057532 0.4424615151658139 3.1854093736512596 0.7466896813620875 1.124873490528456 0.3064733431090838 1.0 1.0 0.0040998381065295 2.7323384312904545e-05 +Regulation of dendrite morphogenesis 2 15 2.156883088846189 0.0310147749158447 3.371359223300971 14.810679611650484 0.2397235631954768 0.5405272987424388 2.5141261287666077 2.1231691197225757 0.8756150368052826 0.2919974595062143 0.0221396463905691 0.0803423183547755 0.1182543832578025 0.4404396671456285 +Ribonucleoside metabolic process 5 8 2.1446845466060824 0.0319780772837741 2.1189320388349513 8.12621359223301 1.1914157696469383 0.2635896161542528 1.2648845164842024 0.7462477223524518 0.9827848183963048 0.2624193088278075 1.0 0.2033176172301104 0.0191106391622076 0.0269295467729808 +Purine ribonucleoside metabolic process 5 8 2.1446845466060824 0.0319780772837741 2.063106796116505 7.834951456310679 1.2047777662844132 0.2574288772305114 1.199068432200366 0.6246876870736083 0.9870596763535292 0.2611531847589775 1.0 0.1486636480545473 0.0072626368836444 0.0078812527225172 +Membrane protein proteolysis 1 11 2.1433806692712296 0.032082544015068 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 0.1690349275366953 0.3155444220122531 0.2497167706923579 0.5850817530243546 +Regulation of protein k63 linked ubiquitination 2 6 2.139617387260784 0.0323857002956931 2.216019417475728 5.844660194174757 -0.0123228826116253 0.5675505252856405 1.577892068002035 0.5746637945486133 0.8488625012231619 0.2923301036905789 1.0 0.1073692926764015 0.2532529321952443 0.018020673376298 +Glandular epithelial cell development 2 7 2.13537078026098 0.0327307354954267 2.0072815533980584 5.247572815533981 -0.0558500384037346 0.5550666489327928 1.4622915213948338 1.4703770509234575 0.8929219066772065 0.2982449953222876 1.0 0.172526836456327 0.082298412398385 0.0701952648708137 +Amino acid betaine metabolic process 1 7 2.1276058238559323 0.033369778964813 2.424757281553398 6.652912621359223 -0.5303235840950383 0.3373366152950036 1.1089524004774276 1.0605074175394698 1.1570448153598685 0.2485913468276022 0.0451714964804377 0.0903020002145616 0.0227865880642579 0.0817606313480972 +Polysaccharide biosynthetic process 1 15 2.1248435981851075 0.033599665541399 3.820388349514563 14.67233009708738 -0.0786807871245417 0.5508609802760668 2.0917711742208227 2.0233854663422006 0.8636927896951768 0.2808854030232299 0.1843129003022452 0.0643053609617777 0.2855675977426195 0.637323462105345 +Glandular epithelial cell differentiation 3 9 2.112534630422567 0.0346406188888717 2.2257281553398056 5.978155339805825 -0.1240789043074417 0.5673939220190088 1.5903282325562635 1.717134804560956 0.8420426108647117 0.2942042521434682 1.0 0.2685126379615966 0.1876112798662428 0.2143350029099695 +Negative regulation of microtubule polymerization or depolymerization 8 14 2.110853112195369 0.0347849393025638 5.383495145631068 14.155339805825244 -0.1212356975763682 0.6213248694701315 3.557914658335111 1.944658012979306 0.8350599012528019 0.3174266256813367 1.0 0.275422289319612 0.1963700434786238 0.0229507437408614 +Methylguanosine cap decapping 4 5 2.107007466250775 0.0351169323918196 2.29126213592233 5.912621359223301 -0.0776582949465311 0.502460193343784 1.5336425828925908 1.3924679223894492 0.9464442183064392 0.2839663247492288 1.0 1.0 0.2712176839291556 0.0225979674873623 +Columnar cuboidal epithelial cell development 2 9 2.104776378350408 0.0353107783005852 2.7524271844660193 7.339805825242719 -0.0022848248516215 0.5709849378184982 1.9262794089131392 1.71969402368901 0.8274923093105596 0.2848194365790099 1.0 0.2473900535744361 0.1617118829485157 0.1766336232289773 +Nucleobase containing small molecule biosynthetic process 4 7 2.1031839377436565 0.0354496938024244 1.7135922330097086 6.725728155339806 0.7645590390237343 0.3868941709719335 1.5487262880443011 0.5167281344531495 1.0510813905138674 0.3156372982117756 1.0 0.1157837219692003 0.003279014583115 0.0027630263410089 +Microtubule depolymerization 9 15 2.094755049843132 0.0361927728149797 6.390776699029126 15.366504854368932 -0.3991532769953149 0.5270341386682836 3.376131579971715 2.275693517994133 0.955964518836966 0.3287812943349837 1.0 1.0 1.0 0.1274755097437061 +Response to light stimulus 23 60 2.092702731091541 0.0363756993161228 12.70873786407767 56.38106796116505 0.0070300704017528 0.7633564533174257 6.037714908774202 7.441873839168449 0.5541923286861473 0.2639102378917758 0.583846576605807 0.0321260030008219 0.0835986831657963 0.0099323467774513 +Negative regulation of protein polymerization 15 26 2.088462731883155 0.0367561138189072 6.514563106796117 25.76456310679612 0.3577422649109862 0.6236942072656753 4.320562885096777 2.176754186789784 0.8134255649148494 0.326257475817155 1.0 0.4447261562683856 0.1866080186666059 0.0792626216408109 +Negative regulation of stress activated protein kinase signaling cascade 7 10 2.085575585491092 0.0370170847991087 3.83495145631068 9.41019417475728 -0.0607437870152996 0.5896640946176641 2.283741978601781 1.2204539029748132 0.8395438390397254 0.2953024296785091 1.0 1.0 1.0 0.8163778738551817 +Cellular carbohydrate biosynthetic process 1 17 2.085085991640553 0.0370614955955457 4.587378640776699 16.968446601941746 -0.2752066142014308 0.5061330694240924 2.2629639302991653 2.2482948262604316 0.8910020429851256 0.2715074734727132 0.1993158438352355 0.0748672511655927 0.3212458225132684 0.6842653425207743 +Amp salvage 3 5 2.076584536836194 0.0378399213041902 1.91747572815534 4.635922330097087 0.265573089223418 0.4091186067198797 1.492045392504656 0.515272454828754 1.1444474328484808 0.294450018392828 1.0 1.0 0.0054816148577098 2.639864710894744e-05 +Negative regulation of actin filament depolymerization 8 16 2.0750188858139302 0.0379847844707663 5.730582524271845 15.975728155339803 -0.0975869682305281 0.6258855335447929 3.4756764586381586 1.4496042995002487 0.7514170529435139 0.2815259984602427 1.0 1.0 0.5840260458969068 0.8338318138494164 +Glial cell development 12 20 2.0743612782374417 0.0380457706704429 5.114077669902913 20.08495145631068 0.342527471970151 0.5482793913252476 2.6656928412824445 3.2664916525364203 0.9072377099594536 0.3081373734674846 1.0 0.4499862992541252 0.0174431156775202 0.0842128339586661 +Meiotic chromosome condensation 5 6 2.071728454845878 0.0382907721311673 2.495145631067961 4.800970873786408 -0.1376716624019681 0.5326480852952579 1.3301856678037194 0.7368254058888809 0.8794430593042172 0.285861970449791 1.0 1.0 1.0 0.2581989334031505 +Striated muscle cell apoptotic process 0 7 2.068738597213456 0.0385706231807265 2.4223300970873787 5.101941747572815 -0.5860053553552291 0.5099100166068848 1.327925021192725 1.2519096544936548 0.7525599317914898 0.3005820862413204 0.1050728360238821 0.2033176172301104 0.442563127116907 0.6975319846227848 +Oligodendrocyte differentiation 9 20 2.0673765692251145 0.0386986843267074 6.665048543689321 19.46359223300971 -0.1060893949161708 0.6711325142033132 4.204648577210429 1.696980387531874 0.6571339286505102 0.270981727363043 1.0 0.4176693971260321 0.0477083989356381 0.019705753473984 +Mitotic dna replication 1 11 2.060206203718 0.0393788321050012 2.383495145631068 10.468446601941748 0.5291269139916243 0.4958647294042109 2.0805431090504256 1.1305443806694238 0.8212345878065992 0.2944725974261764 0.0670021260054199 0.0085055091795532 0.0491545726752397 0.1630814235328921 +Regulation of protein polyubiquitination 3 9 2.0572341915814665 0.0396637040896032 3.04126213592233 7.975728155339806 -0.029285134318154 0.5826494543431631 2.0433995943423655 0.797077918182331 0.8454976809886074 0.3009376964054431 1.0 0.195727907115695 0.4288068787284576 0.0233101974365333 +Positive regulation of oligodendrocyte differentiation 1 5 2.055704482007734 0.039811009649902 2.186893203883495 4.570388349514563 -0.0299640343448112 0.6065782069422913 1.3622949861800449 0.6093103252740967 0.7863757346071948 0.2889433925600352 1.0 0.0903020002145616 0.2159896916124382 0.0817606313480972 +Positive regulation of endothelial cell proliferation 4 10 2.048959095041804 0.0404661149522063 2.5776699029126213 10.847087378640778 0.5110353339210854 0.5145159989917648 2.19139677223592 1.976418321285878 0.797076934554805 0.2911296630341599 1.0 1.0 0.6660978714719568 0.0655768501043339 +Organelle disassembly 14 52 2.044922358332004 0.0408625132639235 11.983009708737864 49.20388349514563 0.433561938027762 0.6160490735942882 4.954374615918461 6.142102393453674 0.8047024382669711 0.3415228222424311 0.0117679192899753 0.0160610147982088 0.0033082282977481 3.346017298380816e-05 +Gmp metabolic process 11 18 2.038473468045366 0.0415026055096663 5.868932038834951 16.24757281553398 -0.0772610438581992 0.5278533667047174 3.80180154347433 1.6537303909231835 0.9843074119667262 0.3104562897132636 1.0 1.0 0.0170176746213231 7.490488694519441e-06 +Protein autoprocessing 1 5 2.037505587289927 0.0415994026068595 1.5606796116504855 4.563106796116505 0.051975984542612 0.6168814496257962 1.089984200594431 0.9102427171521726 0.7702512179435184 0.2846955987066421 0.0495772435513037 0.0045656876518621 0.0274146616230463 0.0968157430558884 +Negative regulation of microtubule polymerization 4 6 2.0272831181225586 0.0426334669825143 2.237864077669903 5.262135922330097 0.2352901922847071 0.518857415759447 1.4553961529795398 0.7168047363604746 0.948671863123279 0.3113242765715758 1.0 0.0903020002145616 0.0227865880642579 0.0009118158302113 +Arf protein signal transduction 3 5 2.025692593833366 0.0427962961244547 1.4635922330097086 3.5315533980582523 0.3748103722207249 0.5743441864827389 1.070856071995656 0.8134038002703691 0.8385315169092559 0.3024051086666693 0.0670021260054199 0.1323778037089543 0.3058660732099017 0.0334620993119388 +Stress activated protein kinase signaling cascade 25 40 2.022324417384665 0.0431428477016391 9.16747572815534 35.592233009708735 0.0363959748886252 0.6968819183055537 5.40887534178808 5.138729572142261 0.7394130543964318 0.3013836593101427 1.0 1.0 0.8886698405792586 0.1287024368621891 +Purine nucleoside biosynthetic process 4 6 2.0223189114351814 0.0431434161444439 1.4611650485436891 5.742718446601942 0.8935109670252933 0.3592786141720023 1.2698698816998135 0.508968486969168 1.0201063575252725 0.3098922359465458 1.0 0.0903020002145616 0.0014512760162947 0.0009118158302113 +Trna processing 17 53 2.0222029985134604 0.0431553846444443 15.944174757281552 42.68689320388349 -0.6392227307717933 0.5011218745097475 6.862681553546122 7.973957798306755 0.9772007781357452 0.3356825254357675 0.4328077398558957 0.3193106634381686 0.0090965420460151 0.0152610451604746 +Regulation of dna methylation 0 10 2.018404573502873 0.0435491434664367 1.9927184466019416 8.83252427184466 0.7131887814592797 0.4532119966636778 1.6480189308548123 1.5386952097280358 0.8551167704417201 0.3087271346477002 0.0755969254036216 0.1486636480545473 0.3388735835116871 0.1985866733922443 +Histone h4 k16 acetylation 0 9 2.0160215347455552 0.0437977239975153 2.1699029126213594 8.91504854368932 0.1952535412729353 0.575754729263669 1.9915518148797284 1.5438782170559378 0.804389199445513 0.2793711065696027 0.1133242047904145 0.2182850433665622 0.4690935769156698 0.3621483333283614 +Rna decapping 5 6 2.0117273772924924 0.0442486830211699 2.4199029126213594 6.279126213592233 -0.0848810557566545 0.4946047197410289 1.6312756311392622 1.6346524269353602 0.9873567578795914 0.2905803749724461 1.0 1.0 0.3225700131084155 0.0397387250697101 +Organic cation transport 1 5 2.00175265226113 0.0453113405245044 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.0041305095198808 0.0163998244725808 0.0895680133917324 0.2715157705871365 +Positive regulation of amyloid precursor protein catabolic process 3 7 2.0004454076877427 0.0454521893308013 2.279126213592233 5.871359223300971 -0.0450573145953618 0.571952895661042 1.647961734165576 1.4616306551004925 0.8563671318045422 0.3064621950738684 0.0755969254036216 0.0108829135912838 0.0617128865328283 0.0465653262864464 +Carnitine metabolic process 0 6 2.0001729796257317 0.0454815884527484 1.8907766990291264 5.584951456310679 0.0609785321453339 0.4105567470620494 1.1105025446134678 0.9976023428885448 1.1033989692507622 0.2543534563670523 0.0362999537782941 0.0729118409275157 0.1768749528600843 0.3285208438252537 +Nuclear body organization 1 5 1.994155448971623 0.0461350691341861 1.854368932038835 4.157766990291262 -0.0247751475991642 0.5747382764018809 1.1461863061279218 0.898684510058506 0.8826318085204585 0.308562578396618 1.0 0.1073692926764015 0.0323840811666381 0.1125747569923622 +Type b pancreatic cell development 1 5 1.991775634154061 0.0463956808132208 1.4733009708737863 3.701456310679612 -0.0529892878897804 0.542159301272675 1.1111813781051234 1.1949317791527294 1.032788839559643 0.3191892585932279 1.0 0.1323778037089543 0.0491545726752397 0.1630814235328921 +Vesicle transport along microtubule 7 12 1.989199664208969 0.0466791689694763 4.514563106796117 11.58980582524272 -0.102125747194735 0.5711972684164484 2.4921783572738394 1.5404554115317726 0.8762002857901487 0.2964402233799867 1.0 1.0 0.6134016456847204 0.5711827040853724 +Regulation of myoblast fusion 2 5 1.982693243477975 0.0474017047590815 1.3422330097087378 4.364077669902913 0.4248698403591905 0.5017887244438167 1.0620838941127295 0.7873211763594862 0.9211907465046666 0.309128603452281 0.040745762787022 0.0816476539699214 0.018519525655472 0.0076703518288617 +Positive regulation of myoblast fusion 2 5 1.982693243477975 0.0474017047590815 1.3422330097087378 4.364077669902913 0.4248698403591905 0.5017887244438167 1.0620838941127295 0.7873211763594862 0.9211907465046666 0.309128603452281 0.0362999537782941 0.0729118409275157 0.0146338936924203 0.0053031795330487 +Ephrin receptor signaling pathway 2 6 1.9810968561781763 0.0475804127935144 2.4271844660194173 6.201456310679611 -0.1395490937685798 0.5471504574353905 1.8267268289812413 2.685939262868652 0.938427878679453 0.2990506917337031 1.0 0.3155444220122531 0.2497167706923579 0.307100773996071 +Negative regulation of cell substrate adhesion 4 10 1.97329302411226 0.0484621872424826 3.7572815533980584 9.572815533980584 -0.2545075157306693 0.5606076619893947 2.2402583910325524 1.8726542180395236 0.8872210153878146 0.3047147734558867 1.0 1.0 0.2051784324027348 0.2403376761227438 +Cellular metabolic compound salvage 6 12 1.972650129481547 0.0485354374525122 2.7111650485436893 10.342233009708735 0.6130022979591714 0.432432246703952 2.283663298329598 1.399328155048808 1.034909334157758 0.3166979119501528 1.0 0.2033176172301104 0.0002248534004763 0.0001024209024739 +Actin filament depolymerization 9 20 1.9668498404015344 0.0492005246921738 7.66747572815534 20.466019417475728 -0.4116865330706377 0.5539944777357779 3.668762183373125 1.7505368606784133 0.8592036450656931 0.3149020817792951 1.0 1.0 0.6896980532676216 0.9087776864936228 +Nucleotide sugar biosynthetic process 4 7 1.9630065265120151 0.0496454156842629 3.5800970873786406 8.45388349514563 -0.7122791676909583 0.3923233991206336 2.064703836467016 1.5549199917041956 0.9770826747715916 0.2982792531343591 1.0 1.0 0.0617128865328283 0.0465653262864464 +Leukocyte homeostasis 7 15 1.9628081455065784 0.0496684709801305 3.4029126213592233 12.177184466019416 0.5028432712633871 0.4794963594230453 1.9872875748080177 2.4917658251002113 0.9479568975066928 0.3126900449378977 1.0 1.0 0.1289094914142556 0.012256850099211 +Alpha beta t cell differentiation 5 11 1.960532732070972 0.0499335560655183 3.0145631067961167 10.315533980582524 0.0059961459623565 0.5316576321586325 2.267281326820642 1.2608563341821548 0.931380131474168 0.2953345406530252 1.0 1.0 0.6820219651095167 0.4011073361813396 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..48ea45822c801a806fbbea32b4de774eb32aa982 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 6527, + "title": "Average number of proteins per term", + "value": 20.0 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b787b2e34819cd87310b0de75cb379ace0072bd8 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a637e795c672a5c3f3e0f468ecc2f610f0c3ebb5 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2369 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein polyubiquitination 0.4789335703393344 2.999861131541684 0.002701027207602 0.9999999784622056 0.6837902728602118 54 Q7Z6Z7,Q13309,P22681,P68036,P49427,Q96FW1,P19474,Q15386,Q9C0C9,Q9ULT8,Q9Y263,O95071,P61086,P55786,Q05086,Q7Z7E8,Q5VTR2,P52888,Q96JP5,Q16763 20 +Protein polymerization 0.4660198754957272 2.979822530379335 0.002884154250395 0.9999999935039662 0.6837902728602118 77 P47756,P62993,Q9Y295,Q9UQB8,Q7Z460,Q6IBS0,Q16512,P47755,P57737,O15020,O00401,Q14008,Q99996,P35611,O00429,Q96S59,Q96CW5,P16949,Q9BTW9,P35241,Q13526,P61086,Q9BSJ2,Q14203,P04350,Q9UEY8,Q14155,Q96P70,Q13153,P36404,P07900,O60610,P35080,P07737,Q15691,Q9BPX3,Q16763 37 +Tissue regeneration 0.8714228366860965 2.8031190141479008 0.0050610989129142 0.999999999999996 0.6837902728602118 7 Q7Z4V5 1 +Cell cycle g1 s phase transition 0.4301919309836021 2.801717511303908 0.0050831361925571 0.9999999999999964 0.6837902728602118 63 Q9Y3I1,Q00535,Q93034,P42771,Q7L2J0,Q96DY7,O96017,P31350,Q13309,P23921,O00743,Q13619,P49427,P11802,O95905,P61289,P35241,Q13617,Q08209,Q6Y7W6,Q13618,P20248,Q04637,P62753,Q7Z7L1,Q07864,Q15058,Q00534,O75179,P27695 30 +Skeletal muscle tissue regeneration 0.8801262512204429 2.691601370500141 0.0071109884064615 1.0 0.6837902728602118 6 Q7Z4V5 1 +Regulation of protein polymerization 0.4196300327733953 2.679733067496812 0.0073680889983771 1.0 0.6837902728602118 63 P47756,Q9Y295,Q9UQB8,Q7Z460,Q6IBS0,Q16512,P47755,O15020,Q14008,Q99996,P35611,P16949,Q9BTW9,P35241,P04350,Q14203,Q9UEY8,Q14155,Q13153,P36404,P07900,P35080,P07737,Q15691,Q9BPX3 25 +Response to nerve growth factor 0.7320831586459091 2.6422623208572618 0.0082354244357754 1.0 0.6837902728602118 10 P22681,Q05086,Q9H4M9,P40818 4 +Lymphocyte homeostasis 0.7309891331930407 2.6415804098227578 0.0082520216309265 1.0 0.6837902728602118 11 P00813,P42574,O95067,P49327,P62753,Q16512 6 +Glucan biosynthetic process 0.7090349527141045 2.5280279418693836 0.0114705222637314 1.0 0.6837902728602118 11 P11310 1 +Peptidyl serine modification 0.41539132143892 2.514187356224273 0.0119307033377769 1.0 0.6837902728602118 70 Q9BV86,Q00535,P33981,P53350,Q13177,P14174,Q7Z460,Q16539,Q92600,O75116,Q13546,Q16512,O96017,Q9Y376,O15111,Q9UGN5,Q99996,Q96N67,P36507,Q13418,P08238,P19784,P78362,Q8IV63,Q13464,Q13043,O14965,P31751,Q04637,P28482,Q16513,Q14012,Q13535,Q7Z4H8,Q13153,Q99986,P07900,Q9UHD2,P35080,P17612 40 +Nucleotide salvage 0.8057777077082986 2.511873274747541 0.0120092205031085 1.0 0.6837902728602118 7 P00813,Q9BZX2,P00492,Q01433,P07741 5 +Mismatch repair 0.6983738475857005 2.483978896471118 0.0129923507338511 1.0 0.6837902728602118 13 P35244,P54277,P20585,P09429,Q9UQ84,P18858 6 +Dna strand elongation involved in dna replication 0.6939954282723629 2.4542684860072557 0.0141171534810404 1.0 0.6837902728602118 12 P25205,P49005,P18858 3 +Ribosome disassembly 0.8245538382824651 2.4525790363994595 0.014183621655083 1.0 0.6837902728602118 6 Q96E11,Q9ULC4,P46199 3 +Neuron death 0.425193522839589 2.4521929575965724 0.0141988498957181 1.0 0.6837902728602118 81 P55210,Q9Y3I1,Q9UMX5,Q00535,P17655,Q9UER7,P22681,P11413,Q15392,P49427,P61081,P48506,P78362,Q01105,P21359,Q96EB6,Q14790,P31751,Q9UL15,P49327,Q13564,Q96B36,P51858,P05198,P45985,Q9UHD2,Q15058,P42574,O95630,P48507 30 +N terminal protein amino acid modification 0.7591405870325082 2.4460407411674168 0.0144434678320268 1.0 0.6837902728602118 8 P50579,Q9BV86,Q5VZE5,Q14CX7 4 +Retrograde axonal transport 0.7253464816425816 2.4391750543459216 0.0147208352623491 1.0 0.6837902728602118 9 Q9NZ32,P43034,P33176,Q14204,P78559,P27695 6 +Barbed end actin filament capping 0.6907257161374798 2.4321903852379427 0.015007816378695 1.0 0.6837902728602118 11 P47756,P35611,Q6IBS0,Q9UEY8,P35241,P47755,Q9BPX3 7 +Astrocyte development 0.9014865882738888 2.422699651398158 0.0154056578318253 1.0 0.6837902728602118 4 P21359,Q13144 2 +Muscle cell differentiation 0.401270862858437 2.3978431667828586 0.0164919247662829 1.0 0.6837902728602118 67 Q96EB6,P11413,P11310,P41440,Q9H4M9,Q92990,P17655,P26358,Q7Z4V5,O75179,P67809,Q86TU7,Q08209 13 +Purine nucleoside monophosphate biosynthetic process 0.6732505844481144 2.374965846655814 0.0175505740371559 1.0 0.6837902728602118 16 P00813,P30520,Q06203,P49915,P00492,P11908,P20839,Q01433,P07741,P30566,P31939,O15067 12 +Positive regulation of calcium ion transport into cytosol 0.804913279857002 2.366473878862861 0.0179584414799061 1.0 0.6837902728602118 6 P78417,P19174,P27695,P42858 4 +Positive regulation of release of sequestered calcium ion into cytosol 0.804913279857002 2.366473878862861 0.0179584414799061 1.0 0.6837902728602118 6 P78417,P19174,P27695,P42858 4 +Positive regulation of dendrite morphogenesis 0.6787720205002279 2.366247249091851 0.0179694392795357 1.0 0.6837902728602118 10 Q9UQB8 1 +Mitochondrion distribution 0.8864994026284304 2.3612119971787475 0.0182153143255767 1.0 0.6837902728602118 4 Q9BUK6,O00429,O75153 3 +Purine containing compound salvage 0.7412315871612077 2.360569761199538 0.018246886041664 1.0 0.6837902728602118 8 P00813,P00492,Q13126,Q01433,P07741,P30566 6 +Peptidyl lysine dimethylation 0.8428548013799615 2.3535023216638535 0.0185974917354276 1.0 0.6837902728602118 5 Q03164 1 +Protein k48 linked ubiquitination 0.6743767722005911 2.3457393223044702 0.0189893832485221 1.0 0.6837902728602118 11 O95071,P49427,P61086,Q05086,Q15386,Q13309 6 +Astrocyte differentiation 0.6744894002577478 2.3436960592835137 0.0190937240244435 1.0 0.6837902728602118 10 P21359,Q13144,Q00534,Q06124,P40763 5 +T cell homeostasis 0.7669056784819458 2.334592269604668 0.019564730777668 1.0 0.6837902728602118 7 P62753,P42574,P49327,O95067 4 +Dna dealkylation 0.7356656523003442 2.333837693059254 0.0196042222867267 1.0 0.6837902728602118 8 P27695,Q93008,Q8N3C0,P29372,Q01804 5 +Imp biosynthetic process 0.7012579777561225 2.3185582867872627 0.0204189990923917 1.0 0.6837902728602118 9 P00492,Q01433,P07741,P30566,P31939,O15067 6 +Imp metabolic process 0.668506484825116 2.3183330814403114 0.0204312258414895 1.0 0.6837902728602118 12 Q06203,P30520,P00492,Q01433,P07741,P30566,P31939,O15067 8 +Purine ribonucleotide salvage 0.7938443506159594 2.3175713191979534 0.0204726304437639 1.0 0.6837902728602118 6 P00492,P00813,P07741,Q01433 4 +Purine nucleotide salvage 0.7938443506159594 2.3175713191979534 0.0204726304437639 1.0 0.6837902728602118 6 P00492,P00813,P07741,Q01433 4 +Base excision repair 0.6567403877350109 2.294119781883503 0.0217836193801548 1.0 0.6837902728602118 17 P28340,P35244,Q9NX46,Q96K76,Q7Z6Z7,Q07864,P29372,P18858,P27695 9 +Glycosyl compound biosynthetic process 0.7249089550258137 2.2819496407406654 0.0224923135978314 1.0 0.6837902728602118 8 P00813,P00492,O60294,Q13126,P07741 5 +Trna methylation 0.6558454465347305 2.2781581249131855 0.0227171581941554 1.0 0.6837902728602118 16 Q9UBP6,Q9UJA5,O60294,Q08J23,Q9BV44,Q7Z4G4,Q7Z2T5,Q8TEA1,P57081 9 +Microtubule polymerization or depolymerization 0.5170830050190242 2.2768976217667354 0.0227923399475475 1.0 0.6837902728602118 43 Q9Y295,Q7Z460,Q15555,P78559,Q16512,Q14008,Q99996,O15344,Q96S59,Q96CW5,P16949,Q9BTW9,P29372,Q92974,Q99661,Q66K74,Q13526,P04350,Q9BSJ2,Q14203,Q14155,Q96P70,Q13153,P36404,Q15058,Q15691 26 +Protein k63 linked ubiquitination 0.6530581396275618 2.2625660946363735 0.0236624501792679 1.0 0.6837902728602118 16 Q9C0C9,Q9ULT8,Q9Y263,O95071,Q96FW1,Q96JP5,P19474,Q16763 8 +Response to interferon beta 0.7807904832746492 2.259552117423962 0.0238490622328204 1.0 0.6837902728602118 6 P17655,P49427 2 +Cellular response to interferon beta 0.7807904832746492 2.259552117423962 0.0238490622328204 1.0 0.6837902728602118 6 P17655,P49427 2 +Base excision repair gap filling 0.7194630287350106 2.255566526303356 0.0240977915509863 1.0 0.6837902728602118 8 P28340,Q9NX46,Q07864,P18858,P27695 5 +Regulation of oligodendrocyte differentiation 0.718489459071984 2.2508420242061775 0.0243955448071733 1.0 0.6837902728602118 8 P21359,Q15382 2 +Gmp biosynthetic process 0.652234075745589 2.235109503931018 0.0254101605918979 1.0 0.6837902728602118 13 P00813,Q06203,P49915,P00492,P20839,P07741,P30566,P31939,O15067 9 +Regulation of peptidyl threonine phosphorylation 0.7147816501843458 2.2328267797181125 0.0255603695717296 1.0 0.6837902728602118 8 Q8IXJ6,P61086,Q04637,P28482,Q8TEW0,Q9Y376 6 +Positive regulation of histone h3 k4 methylation 0.6518583350351125 2.2284654126301993 0.025849495298631 1.0 0.6837902728602118 12 P26358,Q03164 2 +Regulation of chromatin binding 0.7721336498224748 2.2208696188614714 0.0263597935109354 1.0 0.6837902728602118 6 Q7L2J0,Q08209,Q7Z5K2 3 +Nucleoside monophosphate biosynthetic process 0.6155531495745844 2.217589000171013 0.0265828685810458 1.0 0.6837902728602118 26 Q06203,P30520,P11172,P00813,P49915,Q9BZX2,P00492,P33316,P11908,P20839,Q01433,P07741,P27708,P04183,P30566,Q969G6,P31939,O15067 18 +Histone h3 k14 acetylation 0.7091485400948229 2.2053901040190063 0.0274267318679881 1.0 0.6837902728602118 8 Q03164 1 +Fructose 1 6 bisphosphate metabolic process 0.7667359881535549 2.1966676351409005 0.0280441919348444 1.0 0.6837902728602118 6 P17858,P04075,P09972,P08237 4 +Ribonucleoside monophosphate biosynthetic process 0.6260379614096179 2.192020712244334 0.0283780111053058 1.0 0.6837902728602118 22 Q06203,P30520,P11172,P00813,P49915,Q9BZX2,P00492,P11908,P20839,Q01433,P07741,P27708,P30566,Q969G6,P31939,O15067 16 +Amp biosynthetic process 0.6428306502516764 2.179380914235348 0.0293033827701358 1.0 0.6837902728602118 12 P00813,P30520,Q06203,P00492,P07741,P30566,P31939,O15067 8 +Negative regulation of chromatin binding 0.8390083632019067 2.163662150655375 0.0304902878498443 1.0 0.6837902728602118 4 Q7L2J0,Q08209,Q7Z5K2 3 +Regulation of dendrite morphogenesis 0.6357613551133616 2.156883088846189 0.0310147749158447 1.0 0.6837902728602118 15 Q14999,Q9UQB8 2 +Ribonucleoside metabolic process 0.6967429435849889 2.1446845466060824 0.0319780772837741 1.0 0.6837902728602118 8 O60725,P00813,P00492,Q13126,P07741 5 +Purine ribonucleoside metabolic process 0.6967429435849889 2.1446845466060824 0.0319780772837741 1.0 0.6837902728602118 8 O60725,P00813,P00492,Q13126,P07741 5 +Membrane protein proteolysis 0.6366962489229437 2.1433806692712296 0.032082544015068 1.0 0.6837902728602118 11 Q16740 1 +Regulation of protein k63 linked ubiquitination 0.754067730232538 2.139617387260784 0.0323857002956931 1.0 0.6837902728602118 6 Q9Y263,Q96FW1 2 +Glandular epithelial cell development 0.724131467234445 2.1353707802609794 0.0327307354954267 1.0 0.6837902728602118 7 Q00534,Q15382 2 +Amino acid betaine metabolic process 0.7224826733113174 2.1276058238559323 0.033369778964813 1.0 0.6837902728602118 7 P11310 1 +Polysaccharide biosynthetic process 0.6300538791420726 2.1248435981851075 0.033599665541399 1.0 0.6837902728602118 15 P11310 1 +Glandular epithelial cell differentiation 0.6608364584095403 2.112534630422567 0.0346406188888717 1.0 0.6837902728602118 9 Q00534,Q15382,P49327 3 +Negative regulation of microtubule polymerization or depolymerization 0.628727677269685 2.110853112195369 0.0347849393025638 1.0 0.6837902728602118 14 Q7Z460,P04350,Q14155,P16949,Q9BTW9,P29372,Q15691,Q92974 8 +Methylguanosine cap decapping 0.7857783089333625 2.107007466250775 0.0351169323918196 1.0 0.6837902728602118 5 Q86TB9,Q96F86,Q6P2E9,Q96C86 4 +Columnar cuboidal epithelial cell development 0.6593311986763277 2.1047763783504077 0.0353107783005852 1.0 0.6837902728602118 9 Q00534,Q15382 2 +Nucleobase containing small molecule biosynthetic process 0.7173056214778734 2.1031839377436565 0.0354496938024244 1.0 0.6837902728602118 7 P00492,P00813,P07741,Q13126 4 +Microtubule depolymerization 0.6247096959850417 2.094755049843132 0.0361927728149797 1.0 0.6837902728602118 15 Q14008,Q66K74,P78559,Q7Z460,Q15058,P16949,P29372,Q92974,Q99661 9 +Response to light stimulus 0.36597498903594 2.092702731091541 0.0363756993161228 1.0 0.6837902728602118 60 P55210,Q00535,Q96K76,Q15555,P18074,Q96KB5,Q06787,O96017,P27544,O60921,P39748,Q96RU2,Q96EB6,P21359,P28340,P31751,Q13432,P52701,Q13535,P05198,P50570,Q9NPQ8,P42574 23 +Ubiquitin recycling 0.8213859020310568 2.0893288539945125 0.0366781307420003 1.0 0.6837902728602118 4 Q9Y263,P61086,Q16763 3 +Negative regulation of protein polymerization 0.5950855419460265 2.088462731883155 0.0367561138189072 1.0 0.6837902728602118 26 P47756,O15020,P35080,P35611,P04350,Q6IBS0,Q9UEY8,Q14155,P16949,Q9BTW9,P35241,P07737,Q15691,P47755,Q9BPX3 15 +Negative regulation of stress activated protein kinase signaling cascade 0.6261992224652394 2.085575585491092 0.0370170847991087 1.0 0.6837902728602118 10 P43034,P47897,Q96KB5,P51452,P31689,P15311,P78318 7 +Cellular carbohydrate biosynthetic process 0.6200149240074802 2.085085991640553 0.0370614955955457 1.0 0.6837902728602118 17 P11310 1 +Amp salvage 0.7788347701879352 2.076584536836194 0.0378399213041902 1.0 0.6837902728602118 5 P00492,P00813,P07741 3 +Negative regulation of actin filament depolymerization 0.6198611976446349 2.0750188858139302 0.0379847844707663 1.0 0.6837902728602118 16 P47756,O15020,P35611,Q6IBS0,Q9UEY8,P35241,P47755,Q9BPX3 8 +Glial cell development 0.6118969700335666 2.0743612782374417 0.0380457706704429 1.0 0.6837902728602118 20 P49770,P21359,Q00535,Q8IXJ6,P31751,Q13144,Q96P11,Q14232,Q00534,P18074,Q9UPY3,Q8TEW0 12 +Meiotic chromosome condensation 0.7390914524805776 2.071728454845878 0.0382907721311673 1.0 0.6837902728602118 6 Q6IBW4,P42695,Q15021,Q15003,Q9NTJ3 5 +Oligodendrocyte differentiation 0.6107191250586077 2.0673765692251145 0.0386986843267074 1.0 0.6837902728602118 20 P49770,P21359,Q00535,P41240,Q13144,Q96P11,O14744,P18074,Q15382 9 +Mitotic dna replication 0.6214332263921376 2.0602062037179993 0.0393788321050012 1.0 0.6837902728602118 11 P25205 1 +Regulation of protein polyubiquitination 0.6501325155623193 2.0572341915814665 0.0396637040896032 1.0 0.6837902728602118 9 Q9Y263,Q96FW1,Q13309 3 +Positive regulation of oligodendrocyte differentiation 0.7740813718554937 2.055704482007734 0.039811009649902 1.0 0.6837902728602118 5 Q15382 1 +Positive regulation of endothelial cell proliferation 0.6194515888225622 2.048959095041804 0.0404661149522063 1.0 0.6837902728602118 10 Q96EB6,P21359,P40763,P09429 4 +Negative regulation of protein polyubiquitination 0.8117606853199495 2.048500039853085 0.0405110281951737 1.0 0.6837902728602118 4 Q9Y263,Q96FW1 2 +Negative regulation of protein k63 linked ubiquitination 0.8117606853199495 2.048500039853085 0.0405110281951737 1.0 0.6837902728602118 4 Q9Y263,Q96FW1 2 +Organelle disassembly 0.4098498625438515 2.044922358332004 0.0408625132639235 1.0 0.6837902728602118 52 Q92538,P19784,Q99986,O00429,Q9NT62,P46199,P41214,P42858,Q9ULC4,P61960,Q9Y4P1,Q96E11,O95352,P27544 14 +Gmp metabolic process 0.6101416107404702 2.038473468045366 0.0415026055096663 1.0 0.6837902728602118 18 Q9P2T1,P00813,Q06203,P49915,P00492,P12268,P20839,P07741,P30566,P31939,O15067 11 +Protein autoprocessing 0.7699462822293173 2.037505587289927 0.0415994026068595 1.0 0.6837902728602118 5 P17655 1 +Negative regulation of cellular senescence 0.8086046677828302 2.0350780369029824 0.041843021527709 1.0 0.6837902728602118 4 P67809,Q00534 2 +Negative regulation of microtubule polymerization 0.7293430859668021 2.0272831181225586 0.0426334669825143 1.0 0.6837902728602118 6 P16949,Q14155,P04350,Q9BTW9 4 +Arf protein signal transduction 0.7672660855861015 2.025692593833366 0.0427962961244547 1.0 0.6837902728602118 5 Q92538,Q9Y6D5,Q15555 3 +Stress activated protein kinase signaling cascade 0.5087040507641823 2.022324417384665 0.0431428477016391 1.0 0.6837902728602118 40 O00560,P60953,P52564,Q16539,Q99956,Q9UER7,Q96KB5,Q13546,O15344,P36507,O43318,P47897,P09429,P51452,P29372,Q99873,P31689,P49327,P28482,Q92905,P45985,P43034,P46109,P15311,P78318 25 +Purine nucleoside biosynthetic process 0.728256963995417 2.0223189114351814 0.0431434161444439 1.0 0.6837902728602118 6 P00492,P00813,P07741,Q13126 4 +Trna processing 0.3977872876640091 2.0222029985134604 0.0431553846444443 1.0 0.6837902728602118 53 Q9UBP6,Q9UJA5,O60294,Q08J23,O95163,Q99575,P05455,Q92499,O15091,O75818,Q2VPK5,Q9BV44,Q7Z4G4,Q7Z2T5,Q8TEA1,P57081,Q6P1R4 17 +Rna decapping 0.7259414225941572 2.0117273772924924 0.0442486830211699 1.0 0.6837902728602118 6 Q6P2E9,Q96C86,Q9UIV1,Q86TB9,Q96F86 5 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.8021773598953129 2.007691544469419 0.0446760797163046 1.0 0.6837902728602118 4 Q05086,P22681 2 +Organic cation transport 0.7618437830561813 2.00175265226113 0.0453113405245044 1.0 0.6837902728602118 5 Q70HW3 1 +Positive regulation of amyloid precursor protein catabolic process 0.6956663846264521 2.0004454076877427 0.0454521893308013 1.0 0.6837902728602118 7 P42574,O75116,Q96P70 3 +Nuclear body organization 0.7601256287106666 1.994155448971623 0.0461350691341861 1.0 0.6837902728602118 5 P78362 1 +Type b pancreatic cell development 0.7595876726735686 1.991775634154061 0.0463956808132208 1.0 0.6837902728602118 5 Q15382 1 +Vesicle transport along microtubule 0.6082617804114736 1.989199664208969 0.0466791689694763 1.0 0.6837902728602118 12 P43034,Q9Y2T2,O00203,P42858,P33176,Q14204,P27695 7 +Regulation of myoblast fusion 0.7575357096689213 1.982693243477975 0.0474017047590815 1.0 0.6837902728602118 5 P17655,Q9H4M9 2 +Positive regulation of myoblast fusion 0.7575357096689213 1.982693243477975 0.0474017047590815 1.0 0.6837902728602118 5 P17655,Q9H4M9 2 +Ephrin receptor signaling pathway 0.7192584686352973 1.9810968561781763 0.0475804127935144 1.0 0.6837902728602118 6 Q16512,Q14155 2 +Negative regulation of cell substrate adhesion 0.6055827470658574 1.97329302411226 0.0484621872424826 1.0 0.6837902728602118 10 P42771,P21359,Q9P258,Q9BTW9 4 +Cellular metabolic compound salvage 0.6052826779474817 1.972650129481547 0.0485354374525122 1.0 0.6837902728602118 12 P00813,Q9BZX2,P00492,Q13126,Q01433,P07741 6 +Fructose metabolic process 0.793565122376907 1.9708866386037365 0.0487368437640864 1.0 0.6837902728602118 4 P09972,Q00796 2 +Amino acid betaine biosynthetic process 0.9489293186943756 1.9691867003721495 0.0489316555612409 1.0 0.6837902728602118 3 P11310 1 +Actin filament depolymerization 0.5938434213894869 1.9668498404015344 0.0492005246921738 1.0 0.6837902728602118 20 P47756,O15020,Q9BPX3,P35611,Q6IBS0,Q9UEY8,P35241,P47755,P60981 9 +Nucleotide sugar biosynthetic process 0.6878349536779342 1.9630065265120151 0.0496454156842629 1.0 0.6837902728602118 7 Q9NR45,P34949,O95394,Q06210 4 +Leukocyte homeostasis 0.6014460454848021 1.9628081455065784 0.0496684709801305 1.0 0.6837902728602118 15 P00813,P42574,O95067,P09429,P49327,P62753,Q16512 7 +Alpha beta t cell differentiation 0.6033016786526407 1.960532732070972 0.0499335560655183 1.0 0.6837902728602118 11 P00491,P00813,O00203,P09429,P40763 5 +Peptidyl methionine modification 0.751683770684201 1.9567490498725904 0.0503769799712583 1.0 0.6837902728602118 5 P50579,Q5VZE5,Q14CX7 3 +Protein depolymerization 0.4859668564425934 1.9548367344782505 0.0506023438183946 1.0 0.6837902728602118 42 P47756,Q7Z460,Q6IBS0,P78559,P47755,O15020,Q14008,P35611,O15344,P16949,P35241,P29372,Q92974,P60981,Q99661,Q66K74,Q9UEY8,Q15058,Q9BPX3 19 +Microtubule nucleation 0.5993772924307181 1.9510005666808707 0.0510569783744432 1.0 0.6837902728602118 15 Q14008,Q99996,Q7Z460,Q9BSJ2,Q14203,Q96S59,Q96CW5,Q14155,Q96P70,Q16512 10 +Regulation of syncytium formation by plasma membrane fusion 0.7110952914109198 1.9435584532834351 0.0519487200520156 1.0 0.6837902728602118 6 P17655,Q9H4M9 2 +Positive regulation of syncytium formation by plasma membrane fusion 0.7110952914109198 1.9435584532834351 0.0519487200520156 1.0 0.6837902728602118 6 P17655,Q9H4M9 2 +Inositol phosphate metabolic process 0.6559622500583465 1.942457993090365 0.0520816805449306 1.0 0.6837902728602118 8 Q13572,Q96PE3,O95861,Q01968,Q13614 5 +Gmp salvage 0.7863640323525503 1.9400185451868597 0.0523774361186226 1.0 0.6837902728602118 4 P00813,P07741 2 +Regulation of protein depolymerization 0.5503585797286892 1.9372505812452472 0.0527147199592241 1.0 0.6837902728602118 31 P47756,O15020,Q66K74,P29372,P35611,Q7Z460,O15344,Q6IBS0,Q9UEY8,P35241,P78559,Q92974,P47755,Q9BPX3 14 +Endocrine pancreas development 0.6542389516480296 1.9338252015093549 0.0531346231312261 1.0 0.6837902728602118 8 Q00534,Q15382 2 +Energy reserve metabolic process 0.5900228815141926 1.9314955968460807 0.0534217933154268 1.0 0.6837902728602118 19 P11310,Q93100,P08237,P31751,Q06210,P06737,P13807 7 +Smooth muscle contraction 0.5969281978846942 1.925805687457168 0.0541286410460397 1.0 0.6882747490918953 10 O75116,Q86TU7 2 +Pyrimidine containing compound biosynthetic process 0.5952201219016867 1.9187077242933892 0.0550213334122025 1.0 0.6946310312987345 13 P11172,Q9BZX2,P15531,P33316,P17812,P27708 6 +Negative regulation of actin filament polymerization 0.5871872211433773 1.914648085465276 0.0555373983870781 1.0 0.6968655802237917 19 P47756,O15020,P35611,Q6IBS0,Q9UEY8,P35080,P35241,P07737,P47755,Q9BPX3 10 +Cellular response to leptin stimulus 0.7799121060036824 1.91229060375097 0.0558389303595898 1.0 0.6968655802237917 4 Q96EB6,P40763 2 +Response to leptin 0.7799121060036824 1.91229060375097 0.0558389303595898 1.0 0.6968655802237917 4 Q96EB6,P40763 2 +Regulation of carbohydrate biosynthetic process 0.5882003570360322 1.909919761723882 0.0561435452168344 1.0 0.6979979421529107 18 P11310 1 +Limbic system development 0.5811969112515255 1.9046502380172448 0.0568255515357236 1.0 0.6988609426761323 21 P21359,Q00535,P43034,Q13144,Q15058,A0AVT1,Q00534,Q15042,P42574,O75569,P27695 11 +Histone h3 acetylation 0.5883591109465836 1.9016811285989157 0.0572128544569738 1.0 0.6988609426761323 17 O43318,Q03164,Q9UPT9 3 +Positive regulation of chromosome condensation 0.7388706304152912 1.8997274174052192 0.0574689003544026 1.0 0.6988609426761323 5 Q9BPX3,Q15021,Q15003,Q9NTJ3 4 +Mitochondrion localization 0.5891427319536483 1.8985839418459372 0.0576192014041794 1.0 0.6988609426761323 16 O75153,Q9NZ32,O00429,Q9BUK6,P27695 5 +Response to leucine 0.7763763979769247 1.8970673831185447 0.0578190453569957 1.0 0.6988609426761323 4 O00330,Q8IWV7 2 +Regulation of jnk cascade 0.5914886248936624 1.895706630572538 0.0579988480637441 1.0 0.699068282584721 12 O00560,Q92905,P43034,P60953,P31689,P09429,P51452,Q13546 8 +Negative regulation of supramolecular fiber organization 0.4399193833500011 1.8947514431789272 0.0581253388841644 1.0 0.699068282584721 47 P47756,Q7Z460,Q6IBS0,P47755,O15020,P35611,O15344,P16949,Q9BTW9,P35241,P29372,Q92974,Q13045,P04350,Q9UEY8,Q14155,Q99471,P35080,P07737,Q15691,Q9BPX3 21 +Positive regulation of muscle hypertrophy 0.6460687492264213 1.892804784191935 0.0583838351183527 1.0 0.699068282584721 8 O75116 1 +Cellular modified amino acid metabolic process 0.3467003056434669 1.8910266635389672 0.0586207850136726 1.0 0.699068282584721 58 P11310,P41440,P78417,Q14353,O00299,P11413,O60725,O75874,Q9UHG3,P48506,Q8IYS1,Q15648,P31939,Q9NRN7,Q9UKG9,P00374,P11586,Q8WUX2,O60568,P12277,P49419,P28161,P26641 23 +Negative regulation of leukocyte proliferation 0.5905147500710228 1.8904856960056944 0.05869303184563 1.0 0.699068282584721 10 P42574,Q92990,Q16512 3 +Deoxyribonucleoside triphosphate metabolic process 0.6175862231616488 1.8872664201496816 0.0591245006010296 1.0 0.7010036694129368 9 P00813,Q9BY32,Q9H773,P33316,Q9Y3Z3,Q96DE0,P04818 7 +Regulation of phosphatidylcholine metabolic process 0.7740106741876045 1.8868706422948516 0.059177726650303 1.0 0.7010036694129368 4 P17655 1 +T cell differentiation involved in immune response 0.7346146748256535 1.880723278436628 0.0600095713750592 1.0 0.7045506051571927 5 P09429 1 +Cd4 positive alpha beta t cell differentiation 0.7346146748256535 1.880723278436628 0.0600095713750592 1.0 0.7045506051571927 5 P09429 1 +Regulation of microtubule depolymerization 0.5883424513891269 1.878498003601037 0.0603130699143594 1.0 0.7054899772957425 10 Q66K74,P29372,Q7Z460,P78559,Q92974 5 +Enteroendocrine cell differentiation 0.6683473142168428 1.869273048150547 0.0615848358448847 1.0 0.7067023870051388 7 Q00534,Q15382 2 +Positive regulation of neuron death 0.5728218775816227 1.8685893455960751 0.0616799692097425 1.0 0.7067023870051388 22 P78362,P21359,P17655,P49427,Q9UER7 5 +Translational initiation 0.3583866045823641 1.866688045571512 0.0619451641099471 1.0 0.7067023870051388 68 P49770,P61221,Q15056,Q14232,Q9ULC4,Q06787,P41567,Q14152,Q7Z478,O60841,P08708,P46199,O43432,Q92499,O15371,P78344,Q9BY44,Q6PKG0,Q13144,Q9Y262,P41214,O75534,Q04637,Q14240,P05198,Q9NR50,Q92905,O60573,O75821 29 +Positive regulation of cell substrate junction organization 0.6136488714355129 1.866526177024836 0.0619677851887425 1.0 0.7067023870051388 9 P51452,Q13464,Q15555,Q96AC1 4 +Glial cell differentiation 0.4890548300555993 1.866003859971739 0.0620408254564033 1.0 0.7067023870051388 40 P49770,P21359,Q00535,Q8IXJ6,P41240,P31751,Q13144,Q96P11,Q14232,O14744,P18074,Q00534,Q15382,Q06124,P28482,Q9UPY3,P40763,Q8TEW0 18 +Positive regulation of cytoskeleton organization 0.3925860199640663 1.863609871463754 0.0623765103829883 1.0 0.7072271665836354 52 Q9Y295,Q00535,Q9UQB8,Q7Z460,Q9H6U6,O75116,Q16512,O00401,Q14008,Q99996,Q96AC1,P60981,Q14203,Q13153,Q9Y613,P36404,O75351,P35080,Q14204,P07737,Q15691 21 +Rna capping 0.7678839685216082 1.8604229993930264 0.0628257032130235 1.0 0.7094095059860231 4 O60942 1 +Amino sugar metabolic process 0.6123509849700495 1.8596814224876788 0.0629306119144947 1.0 0.7094095059860231 9 P26572,P46926,O60502,Q06210,O95394,Q9UJ70 6 +Fructose 6 phosphate metabolic process 0.6655998211260316 1.8559942455132137 0.0634543782834029 1.0 0.7104060498383722 7 P17858,Q06210,P08237 3 +Pyrimidine ribonucleotide biosynthetic process 0.6377244023251021 1.8507561271632056 0.0642046453709004 1.0 0.7109604615106926 8 P11172,Q9BZX2,P15531,P17812,P27708 5 +Mrna methylation 0.6376394711371121 1.8503273601732035 0.0642663815368942 1.0 0.7109604615106926 8 Q8N1G2,Q86W50 2 +B cell homeostasis 0.7272309899233228 1.8476789390880903 0.0646488024830032 1.0 0.7110882860490217 5 Q16512,P00813 2 +Cellular carbohydrate metabolic process 0.3504855957754948 1.8363102231564912 0.0663117886501423 1.0 0.7154000735859155 64 Q96EB6,P11310,Q13572,Q93100,O75874,P08237,P31751,P48735,P85037,P06737,Q9UNI6,Q00796,P13807,P18669,P40763,Q13614,P46976 17 +Regulation of phospholipid metabolic process 0.6074861905579669 1.8339905733043136 0.0666553934686575 1.0 0.717920384768858 9 Q8WTV0,P17655,Q13614 3 +Cellular glucan metabolic process 0.5763444315166384 1.8313572042867328 0.0670472445363417 1.0 0.7197654031064181 17 P11310,Q93100,P08237,P31751,P06737,P13807 6 +Nucleoside monophosphate metabolic process 0.4905361914185371 1.8260798733813275 0.0678382313989489 1.0 0.7240617811634736 39 P11172,P00813,P27708,Q06203,P30520,P49915,P00492,P33316,P11908,P12268,Q969G6,P31939,Q9P2T1,P20839,Q01433,P07741,P04183,P00491,Q9BZX2,P00568,P30566,O15067 22 +Response to interleukin 4 0.632788745779483 1.825813198849063 0.0678784044826805 1.0 0.7240617811634736 8 P49736,P11802,P39023,P12268,P08238,P49327 6 +Jnk cascade 0.5722795668906315 1.8257283408764668 0.0678911919828475 1.0 0.7240617811634736 19 O00560,Q92905,P45985,P43034,P60953,P31689,Q99956,O43318,P46109,Q9UER7,P09429,P51452,Q13546 13 +Response to temperature stimulus 0.3888822574099106 1.8245039611774228 0.0680759180366177 1.0 0.7248474992251287 52 P49770,P11310,P21359,Q14790,Q13144,Q9UER7,P31689,Q13535 8 +Establishment of centrosome localization 0.6847444532664615 1.8214885792749471 0.0685326211766064 1.0 0.7276919369008364 6 Q9Y613,Q8TEW0,P43034 3 +Deoxyribonucleoside triphosphate catabolic process 0.6843992827256659 1.819880820685737 0.0687771562665298 1.0 0.7276919369008364 6 P00813,Q9BY32,P33316,Q9Y3Z3,Q96DE0 5 +Nucleoside triphosphate catabolic process 0.6843992827256659 1.819880820685737 0.0687771562665298 1.0 0.7276919369008364 6 P00813,Q9BY32,P33316,Q9Y3Z3,Q96DE0 5 +Positive regulation of mitotic cell cycle 0.4316759834195792 1.818341211213544 0.0690119976929091 1.0 0.7276919369008364 47 Q7L2J0,Q96DY7,P31350,P23921,Q13619,P11802,P08243,P51452,P35241,Q9UPT9,Q9P258,Q13618,Q9UJX4,P30307,Q04637,Q06124,Q16513,P43034,P06730,O75179,Q15398,P14635,P27695 23 +Gtp biosynthetic process 0.7565710872162417 1.8114384989821188 0.0700730010456511 1.0 0.7353158807475324 4 P20839,P15531,P22392 3 +Protein localization to cilium 0.5739325520806835 1.800856181244988 0.0717255510726251 1.0 0.7397100565131856 14 Q3SYG4,Q9H4M9 2 +Deoxyribonucleoside metabolic process 0.7540527856581831 1.8005086498456373 0.0717803590138643 1.0 0.7397100565131856 4 P00813,P04183 2 +Protein deneddylation 0.653103667133409 1.7954090226140391 0.0725885559829602 1.0 0.7397100565131856 7 Q92905,Q7L5N1,P61201 3 +Prostanoid metabolic process 0.5731223208534911 1.7924939390935952 0.0730538791863866 1.0 0.7397100565131856 12 Q8N8N7,Q9Y263,Q8N4Q0 3 +Peroxisome proliferator activated receptor signaling pathway 0.7138338103263729 1.787489895213848 0.0738583438609925 1.0 0.7397100565131856 5 Q96EB6,Q96EK7 2 +Negative regulation of inflammatory response to antigenic stimulus 0.6772723855127571 1.786636078559179 0.0739963265361711 1.0 0.7397100565131856 6 P19174,P28070,P25786 3 +Schwann cell development 0.5982226732114488 1.7849208666755825 0.0742741534862978 1.0 0.7397100565131856 9 P21359,Q00535,Q8IXJ6,P31751,Q9UPY3,Q8TEW0 6 +Nucleoside salvage 0.713210440381216 1.7846822143546643 0.0743128774316495 1.0 0.7397100565131856 5 P00492,P07741,Q13126 3 +Purine ribonucleoside salvage 0.713210440381216 1.7846822143546643 0.0743128774316495 1.0 0.7397100565131856 5 P00492,P07741,Q13126 3 +Glycolytic process through fructose 6 phosphate 0.5712655065209012 1.7838452429380436 0.0744488155954661 1.0 0.7397100565131856 10 P85037,P51570,P17858,P08237 4 +Cell junction disassembly 0.749434797888243 1.7804421792407612 0.0750036240827196 1.0 0.7397100565131856 4 Q00535,Q15555 2 +De novo amp biosynthetic process 0.6496912177304144 1.7788115019003492 0.0752706708483854 1.0 0.7397100565131856 7 P31939,Q06203,O15067,P30566 4 +Xmp metabolic process 0.6490284005979136 1.7755851157262053 0.0758013250709048 1.0 0.7397100565131856 7 Q06203,P22102,P12268,P30566,P31939,O15067 6 +Pentose metabolic process 0.7480401347736572 1.7743760388985588 0.0760009705418873 1.0 0.7397100565131856 4 P11413,Q9UKK9 2 +Negative regulation of cell matrix adhesion 0.6487475606385351 1.7742178247633005 0.0760271269248309 1.0 0.7397100565131856 7 P42771,P21359,Q9P258 3 +Positive regulation of mapk cascade 0.4185301755732437 1.7715761342049072 0.0764649442575575 1.0 0.7408310228053389 48 Q9UMX5,Q96AC1,P41240,P36507,P18615,O43318,P30046,P09429,Q06124,O75116,P29372,Q16512 12 +Cytoplasmic translation 0.4086916718786947 1.7655260927248768 0.0774753889264752 1.0 0.7434076548211022 115 P84098,P62906,P61254,P61247,P50914,P46778,P36578,P14618,P27635,P62847,P62241,P55039,O75534,Q14240,P18621,P67809,P46776,Q9Y295,Q9ULC4,Q02543,P62829,P32969,P62701,P62495,P08708,Q9H2P9,P42766,P39019,P11940,P15170,Q9UET6,P05387,P62899,P15880,P62851,P62280,P60842,P39023,P62266,P46783,P62841,P62263,Q15056,P26373,Q06787,Q7Z478,P61313,P62854,Q92597,P62269,P61513,P47914,Q9NZI8,P41214,Q04637,Q9NR50,Q9BQC3,Q13347,P49588,P62750,P60866,P62917,Q9H2U1,O60524,Q14152,P62081,P62273,P61353,P49207,P46781,P46777,O15371,P83731,P55010,P62910,P62753,P08865,O43583,P05388,P62249,Q02878,P62277,P25398,Q8WU90 84 +Regulation of notch signaling pathway 0.7087181862487317 1.7644308135830755 0.077659474149099 1.0 0.7434076548211022 5 Q96TA1,P40763,P49407 3 +Activation induced cell death of t cells 0.7441968290232657 1.7576454259623138 0.0788078589905438 1.0 0.7434076548211022 4 P62753,P49327 2 +Oligodendrocyte development 0.6190283904709819 1.7560048001727897 0.0790875889394042 1.0 0.7434076548211022 8 P49770,Q13144,Q96P11,Q14232,P18074 5 +Female meiosis i 0.7434686239275652 1.7544731236148754 0.079349471234648 1.0 0.7441293085467644 4 Q15645,O95067 2 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.669673259839746 1.7510886028874146 0.0799306491004112 1.0 0.7441656431438878 6 P15531,P27708,Q9BZX2,P17812 4 +Cellular response to acid chemical 0.5633905980121522 1.748755258804025 0.0803333336417879 1.0 0.7441656431438878 16 Q9P2J5,Q9UQB8,P17655,P48506,P26358,Q8IWV7 6 +Dna synthesis involved in dna repair 0.5652680251498989 1.7486151715133986 0.0803575620149468 1.0 0.7441656431438878 11 P28340,P49005,Q07864 3 +Positive regulation of cyclin dependent protein kinase activity 0.7045115028383577 1.745438365772492 0.0809085922782912 1.0 0.7441656431438878 5 P14635,P08238,O75832,O75909 4 +Schwann cell differentiation 0.5641436482403823 1.7441633996287418 0.0811306014353427 1.0 0.7441656431438878 10 P21359,Q00535,Q8IXJ6,P31751,Q8TEW0 5 +Positive regulation of peptidyl threonine phosphorylation 0.7039357299371944 1.742836746277756 0.0813621355711071 1.0 0.7441656431438878 5 P28482,P61086,Q9Y376 3 +Response to hepatocyte growth factor 0.7039139527935413 1.7427383367866944 0.0813793318272497 1.0 0.7441656431438878 5 P48506,Q8IXJ6,P48507,Q15648 4 +Columnar cuboidal epithelial cell differentiation 0.5637038345825529 1.7421332029020693 0.0814851388825919 1.0 0.7441656431438878 14 P07437,Q00534,Q15382,P49327 4 +Cellular response to peptide hormone stimulus 0.3382688808998456 1.7363360225540985 0.0825044373526957 1.0 0.7443167041287517 61 P62993,Q9UQB8,P41240,O75116,O60343,P14618,P11802,P07814,P48506,O00443,P40763,Q96EB6,Q13464,P31751,P20248,Q8TBX8,P07741,Q06124,P14735,P43490,Q99741,Q9Y5X3,O14654,P27695 24 +Positive regulation of membrane potential 0.6659316095402401 1.733548962025067 0.0829981429179407 1.0 0.7443167041287517 6 P31751 1 +Regulation of golgi organization 0.5618160033169727 1.7311691193050267 0.0834216053818619 1.0 0.7446368834156558 10 P28482,P36507,Q99996,Q5VU43 4 +Activated t cell proliferation 0.6653105634024745 1.730635397096653 0.0835168142273137 1.0 0.7446368834156558 6 P42574,P09429 2 +Oocyte differentiation 0.5618214603981172 1.7285849647174427 0.0838834024737407 1.0 0.7446368834156558 12 Q5TAX3,Q9H6S0,Q8NHU6,Q15645 4 +Response to angiotensin 0.6645989488255146 1.7272961425115954 0.0841144916240068 1.0 0.7446368834156558 6 O75116,Q99741,Q13464 3 +Medium chain fatty acid metabolic process 0.7004360925876102 1.7270129618466492 0.0841653356339207 1.0 0.7446368834156558 5 P11310 1 +Negative regulation of protein containing complex disassembly 0.538699700686787 1.7260714336988676 0.0843345622913482 1.0 0.7446368834156558 26 P47756,O15020,Q9NRR5,P35611,Q7Z460,O15344,Q6IBS0,Q9UEY8,P35241,P29372,Q92974,P47755,Q9BPX3 13 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.7368578255674965 1.725641573044145 0.084411915296287 1.0 0.7446368834156558 4 P26196,P40763,Q04637 3 +Anaphase promoting complex dependent catabolic process 0.5870666372469913 1.725577980837696 0.0844233635249862 1.0 0.7446368834156558 9 Q9UJX5,P53350,Q13618,Q9UJX4,Q16763 5 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6376247051884304 1.7199482101969616 0.0854418560394441 1.0 0.7492477869599281 7 Q96EB6,Q96K76 2 +Pyrimidine nucleoside triphosphate biosynthetic process 0.6119190852970464 1.7197899994163317 0.0854706211144873 1.0 0.7492477869599281 8 P15531,P27708,Q9BZX2,P17812 4 +Positive regulation of ubiquitin protein transferase activity 0.5839944752537382 1.709190708627628 0.0874156293887513 1.0 0.7620469574162001 9 P53350,P68036,Q16763,P15880 4 +Myoblast fusion 0.6353472722535354 1.708808908842652 0.0874863519641144 1.0 0.7620469574162001 7 P17655,Q9H4M9 2 +Phototransduction 0.7329075717975326 1.7083858852232092 0.0875647645261452 1.0 0.7620469574162001 4 Q13432,Q15555 2 +Copper ion homeostasis 0.7315254293009457 1.7023436024990568 0.0886909756041842 1.0 0.7660263929536967 4 O75880 1 +Microtubule organizing center localization 0.5531708952848572 1.7020924151896777 0.0887380455399546 1.0 0.7660263929536967 18 Q99996,Q9Y613,P43034,Q9UH99,O14965,Q8TD16,P33176,O43237,Q15398,Q8TEW0 10 +Meiotic cell cycle checkpoint signaling 0.7308841099163577 1.6995391363845889 0.0892176470770227 1.0 0.7660263929536967 4 O60921,Q08J23,Q15645 3 +Positive regulation of actin cytoskeleton reorganization 0.7308709484559996 1.6994815763580495 0.0892284830265355 1.0 0.7660263929536967 4 Q00535,Q9UQB8 2 +Purine nucleobase metabolic process 0.5565281721827019 1.699429358672237 0.0892383141719599 1.0 0.7660263929536967 11 Q9P2T1,P00813,Q06203,P00492,P07741 5 +Dendrite development 0.3944326958942931 1.699207369523496 0.0892801183254792 1.0 0.7660263929536967 50 Q00535,O43815,Q9UQB8,P60953,P78559,Q06787,Q86X55,Q7L576,Q14999,O00401,P00492,Q08209,P78344,Q66K74,P61160,Q15334,Q05086,O60678,Q96HC4,Q14012,P43034,A0AVT1,P46109 23 +Female meiosis chromosome segregation 0.7305854241338074 1.6982328171064685 0.089463828991076 1.0 0.7660263929536967 4 Q6IBW4,Q15003,P33981 3 +Hair follicle maturation 0.6580828972370664 1.6966804790651389 0.0897570852373141 1.0 0.766262777012375 6 P21359,P18074 2 +Regulation of histone h3 k4 methylation 0.5532116208656297 1.6949842592587725 0.0900784068630513 1.0 0.766262777012375 17 P26358,Q6W2J9,Q03164 3 +Germinal center formation 0.8763810092564847 1.6933844949719865 0.0903823042409082 1.0 0.7671330296234172 3 Q16512,P00813 2 +Aorta morphogenesis 0.7292819782159747 1.6925308100948482 0.0905448107450981 1.0 0.7675142593938382 4 Q96AY3 1 +Regulation of microtubule polymerization or depolymerization 0.50558610992692 1.69002500439024 0.0910231710644509 1.0 0.7680317446662673 33 Q9Y295,Q14008,Q99996,Q66K74,P29372,P36404,Q15691,Q7Z460,O15344,Q15555,P04350,Q14203,Q14155,P16949,Q9BTW9,P78559,Q16512,Q92974 18 +Biomineralization 0.5531712619102432 1.6888756643869272 0.0912432597716614 1.0 0.7680317446662673 16 O75116,Q6W2J9,P18074,Q9Y4P1 4 +Regulation of lipid kinase activity 0.6919629518972285 1.6886267331661766 0.091290984275957 1.0 0.7680317446662673 5 Q99570,Q05639,A4D1P6,Q8TBX8 4 +N terminal protein amino acid acetylation 0.7280188194696342 1.687003018571104 0.0916027715328087 1.0 0.7680317446662673 4 Q5VZE5,Q14CX7 2 +Cilium organization 0.3481102140179628 1.6847586761488462 0.0920351406960349 1.0 0.7680317446662673 55 Q9Y5K8,Q15555,Q9NT62,P50395,Q3SYG4,P57076,Q9UHD8,Q9Y3P9,P10155,Q9BW83,P61160,Q14141,Q14203,Q86Y56,Q9UIS9,Q92538,P50570,Q9H4M9,Q9NVG8,P42858,Q01968,Q15691,Q8TC07,P27695 24 +Histone h3 deacetylation 0.655284210285153 1.6835096610204936 0.0922764707319394 1.0 0.7680317446662673 6 Q9H4L7 1 +Imp salvage 0.8736936398924969 1.683073792578642 0.0923608071352304 1.0 0.7680317446662673 3 Q01433,P07741 2 +Vascular endothelial cell proliferation 0.8733950432965024 1.6819278046269852 0.0925828402780521 1.0 0.7680317446662673 3 P40763,P09429 2 +Positive regulation of vascular endothelial cell proliferation 0.8733950432965024 1.6819278046269852 0.0925828402780521 1.0 0.7680317446662673 3 P40763,P09429 2 +Double strand break repair via break induced replication 0.6295964125560619 1.680640595857636 0.0928327455417568 1.0 0.7680317446662673 7 P33991,P33992,P49736,P25205,P33993,Q9BRT9 6 +Meiotic cell cycle 0.3322321141280318 1.6785766438125649 0.0932345816461741 1.0 0.7680317446662673 60 P33981,P42695,O95067,Q9H6S0,Q9UQ84,O60566,Q9UH99,O43684,P46379,Q96CW5,O60921,P35579,Q15645,O14965,Q8IXJ6,Q08J23,Q9BSJ2,P30307,P52701,Q9NTJ3,Q6IBW4,O95347,Q9Y620,Q15021,O43264,Q15003 26 +Ribonucleoside monophosphate metabolic process 0.5084016524790556 1.6773722309598935 0.0934697160116699 1.0 0.7680317446662673 32 P11172,P00813,P27708,Q06203,P30520,P49915,P00492,P11908,P12268,Q969G6,P31939,Q9P2T1,P20839,Q01433,P07741,P00491,Q9BZX2,P00568,P30566,O15067 20 +Positive regulation of cation channel activity 0.6286556016324757 1.676027075505228 0.0937328893208389 1.0 0.7680317446662673 7 P78417,P28161,P27695,P42858 4 +Purine nucleoside triphosphate catabolic process 0.725507765830337 1.676008389862251 0.0937365492595474 1.0 0.7680317446662673 4 Q9Y3Z3,P00813,Q9BY32 3 +Purine deoxyribonucleotide catabolic process 0.7255077658303369 1.6760083898622502 0.0937365492595476 1.0 0.7680317446662673 4 P00491,P00813,Q9Y3Z3 3 +Ovarian follicle development 0.6283042734082553 1.6743038648962054 0.09407089532446 1.0 0.7680317446662673 7 P49770,Q05086 2 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.6520304763044218 1.6681817802707162 0.0952796466024628 1.0 0.7680317446662673 6 Q15648,Q16512,Q13309,Q13153 4 +Positive regulation of myeloid cell apoptotic process 0.869758725157414 1.667966346261488 0.0953224076571659 1.0 0.7680317446662673 3 P42771 1 +Syncytium formation 0.6012290999145182 1.665157338661352 0.0958813697045524 1.0 0.7680317446662673 8 P17655,Q9H4M9 2 +Positive regulation of pattern recognition receptor signaling pathway 0.5755069530153569 1.6638210376960112 0.0961481985040855 1.0 0.7680317446662673 9 P41440,P09429,Q9NUD5 3 +Regulation of dendrite development 0.5450176955641713 1.6617577661207683 0.0965613534970533 1.0 0.7680317446662673 19 Q14999,Q9UQB8 2 +Regulation of stress activated protein kinase signaling cascade 0.5220692633199695 1.661089727242521 0.0966954273272557 1.0 0.7680317446662673 28 O00560,Q92905,P43034,O15344,P60953,P36507,P31689,P28482,Q99873,P47897,Q96KB5,P09429,P51452,P49327,P29372,Q13546,P15311,P78318 18 +Regulation of cell substrate junction organization 0.5431943300142323 1.660609165164552 0.0967919670576349 1.0 0.7680317446662673 20 Q13464,Q96AC1,Q9P258,Q7Z460,Q9H6U6,Q15555,Q9H2G2,P51452,O75116 9 +Negative regulation of protein localization to cell periphery 0.6255078428628431 1.660580555380939 0.0967977168845126 1.0 0.7680317446662673 7 Q9HD26,Q00610,Q9ULT8,P41240 4 +Rna guanine n7 methylation 0.685582851083925 1.6596557937668832 0.0969837172284644 1.0 0.7680317446662673 5 P57081 1 +Regulation of dendritic spine morphogenesis 0.5495597931241806 1.6590743844659723 0.097100804247173 1.0 0.7680317446662673 13 Q9UQB8 1 +Activation of nf kappab inducing kinase activity 0.6854253051726498 1.6589397031431965 0.0971279431405469 1.0 0.7680317446662673 5 O43318,Q96JP5 2 +Negative regulation of b cell proliferation 0.7206024458435007 1.654508540931983 0.0980242293976281 1.0 0.7680317446662673 4 P42574,Q16512 2 +Regulation of protein containing complex disassembly 0.4625960815344612 1.6535465573517731 0.0982196789945164 1.0 0.7680317446662673 40 P47756,Q7Z460,Q92900,Q6IBS0,P78559,P47755,O15020,P35611,O15344,P62495,P35241,P29372,Q92974,P60981,Q66K74,P63241,Q9UEY8,Q9NRR5,Q9BPX3 19 +Dna dependent dna replication 0.3498980200061889 1.6514074078037615 0.0986554132317709 1.0 0.7680317446662673 75 P78362,P28340,P41440,Q9UBD5,P25205,Q9BTE3,P49427,Q07864,Q13535,P18858,P49005,P23921,Q7Z7L1 13 +Modification of postsynaptic structure 0.6236326071448549 1.6513708312865754 0.0986628770869662 1.0 0.7680317446662673 7 P35080,P07737,P60953,Q9UQB8 4 +Trna 5 leader removal 0.623558450400639 1.6510065140462296 0.098737244784008 1.0 0.7680317446662673 7 O75818,O15091,P05455 3 +Glucosamine containing compound metabolic process 0.6836669395966224 1.6509451882019095 0.0987497675638751 1.0 0.7680317446662673 5 P46926,O95394,O60502 3 +Actin filament severing 0.6230343892532837 1.6484316566639172 0.0992641243625387 1.0 0.7680317446662673 7 P35579,Q9BPX3,P60981,Q13045 4 +Inflammatory cell apoptotic process 0.6473126138804574 1.6459275839238054 0.0997786691106985 1.0 0.7686318580970127 6 Q96EB6,P42771 2 +Oocyte maturation 0.6469744890897646 1.6443313544790548 0.1001077760934205 1.0 0.7696153763978283 6 O14965,Q5TAX3,Q15645 3 +Rhythmic process 0.3343912500175767 1.6388319113659848 0.1012482712194882 1.0 0.7729210131574263 64 Q00653,Q96EB6,Q03164,Q00535,P42574,O00429,Q06210,O14744,Q05086,O75116,P43490,O95352 12 +Regulation of alpha beta t cell differentiation 0.5952400749746583 1.6344616959875364 0.1021619427908202 1.0 0.7771689983632678 8 P09429,P00491,P00813,O00203 4 +5 phosphoribose 1 diphosphate metabolic process 0.7150537634408549 1.6301550694706848 0.1030687272418082 1.0 0.7822437008224217 4 P11908,P06737,O60256 3 +Endothelial cell proliferation 0.5421337703047835 1.623970141693965 0.1043821811522116 1.0 0.7893287405185895 16 Q96EB6,P21359,Q8WTV0,P09429,P40763 5 +Regulation of synaptic vesicle recycling 0.6774394620978968 1.6225991410722125 0.1046751242530301 1.0 0.7893287405185895 5 Q00535,Q9Y263,Q13464 3 +Peptidyl histidine modification 0.7131941788848942 1.6219855087815769 0.1048064509846828 1.0 0.7893287405185895 4 Q9BQC3,Q86TU7 2 +Dna replication checkpoint signaling 0.6770486355428567 1.620818540743718 0.1050565609595113 1.0 0.7893287405185895 5 Q13564,O60921 2 +Mitotic dna replication checkpoint signaling 0.6770486355428567 1.620818540743718 0.1050565609595113 1.0 0.7893287405185895 5 Q13564,O60921 2 +Regulation of microtubule cytoskeleton organization 0.3234335815549146 1.6200190975230098 0.1052281745919816 1.0 0.7893287405185895 57 Q9Y295,P53350,Q7Z460,Q15555,P78559,Q16512,Q14008,Q99996,O15344,P16949,Q9BTW9,P29372,Q92974,Q66K74,Q13464,P04350,Q8IX90,Q14203,Q14155,Q13153,P43034,P36404,O75351,Q8TD16,Q14204,Q15691,Q8NI35 27 +Nucleoside diphosphate metabolic process 0.402151236715013 1.615120213472031 0.1062846643915595 1.0 0.7928228622670965 48 P11172,P85037,P27708,P22392,Q96DE0,P31350,P23921,P04075,P09972,P08237,P14618,P17858,P40763,P00338,P36871,P51570,P36404,P15531,P00568,Q9UKK9,Q9BW91,P30085,Q01813,P00558,P18669,Q00013 26 +Fatty acid transmembrane transport 0.6160498035142415 1.614073565659811 0.106511470371724 1.0 0.7936077250185419 7 O43772 1 +Deoxyribose phosphate metabolic process 0.5415887101188108 1.6132894467344845 0.1066816382358752 1.0 0.7939692733928826 13 P00491,P00813,Q9H773,P33316,Q9Y3Z3,Q96DE0,P31350,P23921,P04818 9 +Polysaccharide metabolic process 0.5333160073814681 1.6111215804892616 0.1071532255728469 1.0 0.7965707327038402 21 P11310,Q93100,P08237,P31751,P06737,P13807,P46976 7 +Nadh regeneration 0.5899848647630224 1.6074783898937002 0.1079494661870881 1.0 0.7992562713146344 8 P85037,P17858 2 +Activation of gtpase activity 0.538286379584857 1.6064130207159837 0.108183191870858 1.0 0.7992562713146344 17 Q96N67,O60343,Q9P258,Q86X10,Q9H8V3,Q9H6U6,P31751,Q9Y3P9,P46109,Q8TC07 10 +Synaptic vesicle cytoskeletal transport 0.7091443707863896 1.6041808462232363 0.1086741954172905 1.0 0.7992562713146344 4 Q9Y2T2,O00203 2 +Trna modification 0.4838085407716939 1.6020585873787847 0.1091426545284934 1.0 0.7992562713146344 35 Q9UBP6,Q9UJA5,Q9NPF4,O60294,Q08J23,O95163,P05455,Q2VPK5,Q9BV44,Q7Z4G4,Q7Z2T5,Q8TEA1,P57081,Q6P1R4 14 +Positive regulation of cilium assembly 0.611802346945268 1.5931439086920836 0.1111279110236638 1.0 0.7992562713146344 7 P27695,P42858 2 +Regulation of cell projection assembly 0.391831559178618 1.5916903300212004 0.1114543021659835 1.0 0.7992562713146344 49 P47756,Q9Y2A7,Q8NCA5,Q9NQW6,P60953,Q9H6U6,Q9NT62,P50395,Q15555,Q6IBS0,Q06787,Q7L576,O00401,Q9UHD8,P51114,Q9Y3P9,P35241,P51116,Q9P258,P61160,Q16658,Q96C92,Q14195,P50570,Q9NVG8,P42858,P35080,P07737,Q8TC07,P27695 30 +Long chain fatty acid biosynthetic process 0.849805912212602 1.5911879231032742 0.1115672899606994 1.0 0.7992562713146344 3 Q96PU8,O00154 2 +Neurotrophin signaling pathway 0.5610068927373058 1.586009507644518 0.1127371528157223 1.0 0.7992562713146344 9 Q96B36,Q06124,P27695 3 +Tubulin complex assembly 0.6693418473751506 1.585668496053534 0.1128145292643243 1.0 0.7992562713146344 5 Q15813,Q9BTW9 2 +Regulation of protein serine threonine kinase activity 0.3340330889642154 1.5855883966737534 0.1128327100985333 1.0 0.7992562713146344 67 O00410,Q9Y3I1,P53350,P14174,P41240,P52564,O95067,P42771,P46940,Q02750,Q16512,Q53EL6,Q9Y376,P36507,O43318,P08238,O75832,Q96AC1,P31689,Q9UHD1,Q96EB6,P21359,Q9UII4,P49736,Q13043,P04035,P20248,P30307,Q16543,Q14012,Q12802,Q99741,O95373,Q13153,Q9NYV4,Q9Y4R8,Q99816,Q9P287,O75909,P42858,P42574,P14635 42 +Regulation of actin filament organization 0.3325222751240164 1.5832508466224344 0.113364301363843 1.0 0.7992562713146344 66 P47756,P62993,Q9UQB8,Q7Z460,Q6IBS0,O75116,Q16512,P47755,O15020,O00401,P35611,P16949,Q96AC1,P35241,P60981,Q13464,Q13045,Q9UEY8,Q13153,P35080,P07737,Q9Y613,Q9BPX3 23 +Protein k11 linked ubiquitination 0.5849875990214195 1.581779614790479 0.1136998902524832 1.0 0.7992562713146344 8 Q9UJX4,P68036,Q16763,Q9UJX5 4 +Scf dependent proteasomal ubiquitin dependent protein catabolic process 0.5849013964600204 1.5813359842989927 0.1138012360201627 1.0 0.7992562713146344 8 Q13619,Q93034,Q15058,Q13617,Q13309 5 +Response to staurosporine 0.8471185428486177 1.5808268417393223 0.1139176354342339 1.0 0.7992562713146344 3 P55212,P42574 2 +Regulation of histone h3 k14 acetylation 0.8470715610383017 1.5806456660184192 0.1139590781649431 1.0 0.7992562713146344 3 Q03164 1 +Axonal transport of mitochondrion 0.7036143500815027 1.57984093527022 0.114143298403464 1.0 0.7992562713146344 4 Q9NZ32 1 +Positive regulation of rig i signaling pathway 0.8467392690665891 1.579364212811281 0.1142525409917629 1.0 0.7992562713146344 3 Q9NUD5 1 +Cell substrate junction organization 0.5160426460575944 1.5783102978463457 0.114494341302783 1.0 0.7992562713146344 26 Q13464,Q96AC1,Q9P258,Q9HCM4,Q03001,Q7Z460,Q9H6U6,Q15555,Q9H2G2,Q14155,P51452,O75116,Q9Y490 13 +Negative regulation of cell junction assembly 0.6329204616519422 1.5778396635248104 0.1146024491964472 1.0 0.7992562713146344 6 O75116,Q9H6U6,Q9P258 3 +Regulation of b cell proliferation 0.55886080328732 1.5744634196782588 0.1153803520066873 1.0 0.7992562713146344 9 P42574,Q16512,P00813 3 +Heart valve morphogenesis 0.6667996158163709 1.5740582672149144 0.1154739794468668 1.0 0.7992562713146344 5 O75116 1 +Cellular response to cadmium ion 0.6314438634581829 1.5708380019215555 0.116220282488747 1.0 0.8025106036025215 6 P28482,Q9UER7 2 +Mitochondrial fragmentation involved in apoptotic process 0.7006889120011842 1.5669525656526049 0.1171257794424707 1.0 0.8064134624694159 4 O00429,Q9NT62 2 +Purine nucleoside monophosphate metabolic process 0.5139993669649916 1.5649449287991803 0.117595822718131 1.0 0.8077447845125021 26 Q9P2T1,P00491,P00813,P30520,Q06203,P49915,P00492,P00568,P11908,P12268,P20839,Q01433,P07741,P30566,P31939,O15067 16 +Negative regulation of t cell proliferation 0.5815372616942978 1.5640145056130956 0.1178141619206223 1.0 0.8077447845125021 8 P42574,Q92990 2 +N terminal peptidyl methionine acetylation 0.841743804120626 1.5600919813299412 0.1187381462187553 1.0 0.8100326347953258 3 Q5VZE5,Q14CX7 2 +Regulation of tissue remodeling 0.6049675168576045 1.5594112897630517 0.1188990659028919 1.0 0.8100326347953258 7 O75116,P21359,Q08209 3 +Actin polymerization or depolymerization 0.3960950759131558 1.5571382791059396 0.1194376584352236 1.0 0.8100326347953258 48 P47756,P62993,O15020,O00401,Q9BPX3,Q9UQB8,P35611,O60610,Q6IBS0,Q9UEY8,P35080,P35241,P07737,P47755,P60981,P57737 16 +P38mapk cascade 0.6044589806404179 1.5568989389202992 0.1194944814303247 1.0 0.8100326347953258 7 O43318,Q99873,P15311,Q16539 4 +Formation of translation preinitiation complex 0.555562972973029 1.5567072894671865 0.119539997189414 1.0 0.8100326347953258 9 Q7Z478,Q9ULC4,P41214,Q15056 4 +Caveolin mediated endocytosis 0.6982720283995711 1.5562985478953657 0.1196371165838354 1.0 0.8100326347953258 4 Q13432 1 +Response to amphetamine 0.8397582439294007 1.5524279408264074 0.120559862229169 1.0 0.8113776730016219 3 Q08209 1 +Negative regulation of lymphocyte differentiation 0.6617747311719357 1.5510887841847212 0.1208804086381496 1.0 0.8113776730016219 5 Q9Y3I1,P09429 2 +Trna 5 end processing 0.554516235427251 1.5510681229797532 0.1208853594137364 1.0 0.8113776730016219 9 O75818,O15091,P05455 3 +Negative regulation of t cell receptor signaling pathway 0.6970693110976145 1.55099475938131 0.1209029398597156 1.0 0.8113776730016219 4 P51452,Q96IZ0 2 +Negative regulation of antigen receptor mediated signaling pathway 0.6970693110976145 1.55099475938131 0.1209029398597156 1.0 0.8113776730016219 4 P51452,Q96IZ0 2 +Phosphatidylcholine biosynthetic process 0.6030244695340582 1.5498101270459834 0.1211870956375702 1.0 0.8113776730016219 7 P17655 1 +Cochlea development 0.6269388079384868 1.5494589921857571 0.1212714220716362 1.0 0.8113776730016219 6 Q9BW83,P20248,P49736,P43034 4 +Heart valve development 0.5786679147857094 1.5492280575299378 0.1213269069635942 1.0 0.8113776730016219 8 O75116,P20248 2 +Pathway restricted smad protein phosphorylation 0.6950418160095477 1.542050881400458 0.1230612296466606 1.0 0.8212890039915686 4 P33981,Q13526,P67870 3 +Coenzyme a metabolic process 0.5273063285519504 1.5372446204558805 0.1242334173085906 1.0 0.8248947250998686 10 Q9NVE7,P53396,Q13057,O00154 4 +Protein k29 linked ubiquitination 0.8348722600810494 1.5335598279161022 0.1251379775683319 1.0 0.8281093107756824 3 Q15386 1 +Response to cobalt ion 0.8347013338952524 1.532899549027574 0.1253006070243827 1.0 0.8281093107756824 3 Q14790 1 +Coenzyme a biosynthetic process 0.6233745836263586 1.5325271198061297 0.1253924105390127 1.0 0.8281093107756824 6 Q9NVE7,O00154 2 +Vasculogenesis 0.5752105382227181 1.531396676905577 0.1256713848974548 1.0 0.8285425547734223 8 Q92990,Q14999 2 +Myeloid cell apoptotic process 0.6226032107345034 1.5288607322967764 0.1262989726800523 1.0 0.8305193399809484 6 Q96EB6,P42771 2 +Regulation of myeloid cell apoptotic process 0.6226032107345034 1.5288607322967764 0.1262989726800523 1.0 0.8305193399809484 6 Q96EB6,P42771 2 +Lymphocyte costimulation 0.6915278753840393 1.5265413550230238 0.1268750994476302 1.0 0.8315326503195881 4 Q06124 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.5254020501445826 1.5264842538237429 0.1268893089808962 1.0 0.8315326503195881 10 Q96EB6,P61254,P13693,Q96K76 4 +Pyrimidine ribonucleotide metabolic process 0.5495565141430019 1.5243274582973982 0.1274269312643285 1.0 0.8325481284907634 9 P11172,Q9BZX2,P15531,P17812,P27708 5 +Ribonucleoside monophosphate catabolic process 0.6900373540459359 1.51995947990076 0.1285211598385982 1.0 0.834684189319931 4 P00492,P00813 2 +Purine nucleoside monophosphate catabolic process 0.6900373540459359 1.51995947990076 0.1285211598385982 1.0 0.834684189319931 4 P00492,P00813 2 +Nucleotide excision repair 0.5179109723613732 1.515773008529457 0.1295767593430583 1.0 0.8390352264207755 21 Q96EB6,P28340,P35244,Q92759,Q07864,P18074,O60921 7 +Regulation of dendritic spine development 0.5230452121824964 1.5082880738659004 0.1314808142239507 1.0 0.8403743816677205 15 Q05086,Q9UQB8 2 +Peptidyl arginine n methylation 0.6869772998805187 1.5064412166744214 0.1319539466875983 1.0 0.8403743816677205 4 O14744,Q99873,O60678 3 +Peptidyl arginine methylation 0.6869772998805187 1.5064412166744214 0.1319539466875983 1.0 0.8403743816677205 4 O14744,Q99873,O60678 3 +Pyroptosis 0.6865718141279797 1.504649370157214 0.1324142462234827 1.0 0.8403743816677205 4 P55212 1 +Cd4 positive alpha beta t cell activation 0.5937535997132216 1.503935681793609 0.1325979284204363 1.0 0.8403743816677205 7 P09429 1 +Regulation of glucose metabolic process 0.5041631097096995 1.5005403426492143 0.1334744914905905 1.0 0.8403743816677205 26 P11310,P85037 2 +Cellular response to testosterone stimulus 0.8259580275522661 1.4991067716788282 0.1338459351499938 1.0 0.8403743816677205 3 O75116 1 +Microtubule polymerization 0.4829856074513053 1.4975110814699903 0.1342603243439057 1.0 0.8403743816677205 32 Q14008,Q9Y295,Q99996,Q15691,P36404,Q7Z460,P04350,Q9BSJ2,Q14203,Q96S59,Q96CW5,Q14155,P16949,Q9BTW9,Q96P70,Q16512 16 +Cellular response to alkaloid 0.5686382150837286 1.4974587201102705 0.134273939002401 1.0 0.8403743816677205 8 P55212,P42574,P20248,P28161 4 +Response to amine 0.6499422086776765 1.4968986789870018 0.1344196240159787 1.0 0.8403743816677205 5 Q08209 1 +Negative regulation of protein import into nucleus 0.8253799297398883 1.4968712786430909 0.1344267548763213 1.0 0.8403743816677205 3 P61960 1 +Protein localization to microtubule 0.5443663591072785 1.496310016924782 0.1345728859812742 1.0 0.8403743816677205 9 P29372,O60610,Q15555,Q96Q89,P78559,Q15691 6 +Nucleobase biosynthetic process 0.5208483657719776 1.495391752204536 0.134812231806066 1.0 0.8403743816677205 15 P11172,P00813,Q06203,P00492,P17812,P07741,P27708 7 +Purine nucleotide catabolic process 0.5205153763553176 1.4952353668845613 0.1348530264293139 1.0 0.8403743816677205 11 P00491,P00813,O00154,Q9BY32,P00492,Q9Y3Z3,Q96DE0 7 +Ruffle assembly 0.5202850196577321 1.4939228708055885 0.1351957798750782 1.0 0.8403743816677205 11 Q8NCA5,O15357,Q9P258,P35080,P35241,P07737 6 +Negative regulation of phagocytosis 0.5916956548273262 1.4937389962080103 0.135243851746412 1.0 0.8403743816677205 7 P41240,O60493,P09429,Q9NT62 4 +Regulation of tumor necrosis factor mediated signaling pathway 0.5675837320574046 1.49200889999642 0.13569681218413 1.0 0.8403743816677205 8 Q14790,Q96BN8,Q12933,P0DMV9,P61086,Q99829,Q13546 7 +Integrin activation 0.6836668139830024 1.4918085154485905 0.1357493509404523 1.0 0.8403743816677205 4 Q96AC1,Q15058 2 +Establishment of tissue polarity 0.5429610044230986 1.4887180490217302 0.1365616301325769 1.0 0.8403743816677205 9 O95487,Q92796 2 +Cell cycle dna replication 0.5173756004776181 1.4872113173006254 0.136959007935967 1.0 0.8403743816677205 18 P33991,Q9BRX5,P49736,Q9BY42,P25205,Q92900,P39748,Q15554,P33993,P18858 10 +Regulation of cyclin dependent protein kinase activity 0.5045865941404664 1.4858198761098265 0.1373267713196417 1.0 0.8403743816677205 25 O00410,Q9Y3I1,Q9UII4,Q99741,O95373,P49736,P53350,O95067,P42771,O75909,P20248,P08238,O75832,P30307,P42574,P14635,Q16543 17 +Connective tissue replacement 0.8224443997631388 1.4855176447798526 0.1374067528339249 1.0 0.8403743816677205 3 O75116 1 +Positive regulation of tissue remodeling 0.8224443997631388 1.4855176447798526 0.1374067528339249 1.0 0.8403743816677205 3 O75116 1 +Regulation of connective tissue replacement 0.8224443997631388 1.4855176447798526 0.1374067528339249 1.0 0.8403743816677205 3 O75116 1 +Positive regulation of connective tissue replacement 0.8224443997631388 1.4855176447798526 0.1374067528339249 1.0 0.8403743816677205 3 O75116 1 +Neuron projection organization 0.5066895957215508 1.483586627441154 0.1379186191929831 1.0 0.8403743816677205 24 O00401,Q00535,Q96QK1,Q9UQB8,P61160,P43034,P60953,Q15334,Q14203,Q05086,O60678,P78559,Q13614 13 +Cellular response to thyroid hormone stimulus 0.6468497504590446 1.4827146284700907 0.1381502463591717 1.0 0.8403743816677205 5 P48506,Q15648,P48507 3 +Focal adhesion assembly 0.5121111166702602 1.4798058240283676 0.1389250739726475 1.0 0.8403743816677205 21 Q13464,Q96AC1,Q9P258,Q9HCM4,Q7Z460,Q9H6U6,Q9H2G2,Q14155,P51452,O75116 10 +Regulation of macrophage apoptotic process 0.8205434458047076 1.4781637049019325 0.1393639660963455 1.0 0.8414344072395902 3 Q96EB6,P42771 2 +Macrophage apoptotic process 0.8205434458047076 1.4781637049019325 0.1393639660963455 1.0 0.8414344072395902 3 Q96EB6,P42771 2 +Positive regulation of supramolecular fiber organization 0.4157666308397399 1.4755769416895452 0.140057498975394 1.0 0.8415756080468312 44 O00401,Q9Y295,Q14008,Q99996,Q96AC1,Q9UQB8,Q15691,Q13153,Q7Z460,P36404,Q9Y613,Q14203,P35080,O75116,P07737,Q16512,P60981 17 +Positive regulation of stress fiber assembly 0.5172308856640689 1.4727645552979942 0.1408145328400003 1.0 0.8415756080468312 13 Q96AC1,O75116,Q16512,Q9Y613 4 +Regulation of nervous system process 0.5169733800421954 1.4725323172206313 0.1408771866806413 1.0 0.8415756080468312 12 O75116,Q99996,Q9UQB8 3 +Deoxyribonucleoside monophosphate metabolic process 0.5637801677750377 1.4723411408634244 0.1409287788563178 1.0 0.8415756080468312 8 P00491,P00813,P33316,P04183,P04818 5 +Aorta development 0.5871079507057886 1.470991810231996 0.1412933317114171 1.0 0.8417297739294137 7 Q9ULT8,O95487,Q96AY3 3 +Meiotic cell cycle phase transition 0.6786140979689252 1.469459860552682 0.1417081013427052 1.0 0.8417297739294137 4 P33981,P30307,O95067 3 +Positive regulation of lipid storage 0.6436031711990524 1.467815136077929 0.1421544448644365 1.0 0.8417297739294137 5 Q8WTV0,Q9H4M9 2 +Striated muscle cell differentiation 0.4146725336297333 1.466005829572344 0.142646698708623 1.0 0.8417297739294137 44 P11310,Q9H4M9,P17655,P67809,Q08209 5 +Aggrephagy 0.8173446540589304 1.4657862307387837 0.1427065333907797 1.0 0.8417297739294137 3 P42858 1 +Fc epsilon receptor signaling pathway 0.8172588832487255 1.4654543018502897 0.142797011508184 1.0 0.8417297739294137 3 O43318,P19174 2 +Autophagy of nucleus 0.6775380104363902 1.4646980159539933 0.1430033264971051 1.0 0.8417297739294137 4 O95352,Q9NT62 2 +Regulation of biomineralization 0.5385073843548611 1.4646443529764126 0.1430179744580542 1.0 0.8417297739294137 9 O75116,Q6W2J9 2 +Neurotrophin trk receptor signaling pathway 0.6089915648682698 1.4640575870807944 0.1431782144606215 1.0 0.8419136989049338 6 Q96B36,P27695,Q06124 3 +Regulation of rac protein signal transduction 0.676053489008035 1.4581275944293952 0.1448053766419068 1.0 0.845119045945495 4 P21359 1 +Udp n acetylglucosamine metabolic process 0.6408724230654181 1.4552765753522583 0.1455927088867288 1.0 0.8465457304932275 5 P26572,Q16222,O95394,Q06210 4 +L ascorbic acid metabolic process 0.675328554360803 1.4549185771952435 0.1456918041867385 1.0 0.8465457304932275 4 P48506,P78417,P11166 3 +Translational termination 0.5838033647146026 1.4545938393281528 0.1457817375631052 1.0 0.8465457304932275 7 P61221,P15170,P62495,Q92900,P63241 5 +Deoxyribonucleotide biosynthetic process 0.5828462991480492 1.4498428179743037 0.1471023561722084 1.0 0.8534551810986707 7 P31350,P33316,P23921,P04818 4 +Mapk cascade 0.3612413176161805 1.4455506495987471 0.1483032770085119 1.0 0.8562150206210423 98 O00560,P62993,Q9UMX5,P60953,P41240,P52564,Q99956,Q16539,P46940,Q9UER7,Q96KB5,O75116,Q16512,Q13546,Q14152,P63104,O15344,P36507,Q96S59,P47897,P30046,O43318,P09429,P51452,O75832,Q96AC1,P29372,P31689,Q99873,P49407,P21359,Q8IV63,Q13526,Q13464,Q13043,P20248,Q96P70,P49327,Q06124,P28482,P30086,P45985,P43034,Q92905,Q13153,P18615,P46109,O14744,P15311,P78318 50 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.5817462573296064 1.4443810394111756 0.1486318212028847 1.0 0.8562399796921701 7 Q9Y3I1,O95373,P53350,P42771,P42574 5 +Hypothalamus development 0.6723134699207105 1.4415686146590192 0.1494241077431504 1.0 0.8580388448966013 4 O75569,Q15042 2 +Regulation of postsynaptic membrane potential 0.5115552506904134 1.4414063413332054 0.1494699198172875 1.0 0.8580388448966013 12 Q15042,Q08209,Q13614,Q9UQB8 4 +Chemical synaptic transmission postsynaptic 0.5115552506904134 1.4414063413332054 0.1494699198172875 1.0 0.8580388448966013 12 Q15042,Q08209,Q13614,Q9UQB8 4 +Purine nucleobase biosynthetic process 0.5336849765108709 1.4385546262401028 0.1502767498207298 1.0 0.8598036724603544 9 P00492,P00813,P07741,Q06203 4 +Rna modification 0.3190226098121574 1.4337974205516215 0.1516300813066848 1.0 0.8598036724603544 65 Q9NPF4,Q9BV44,Q96HR8,Q7L2J0,Q7Z2T5,Q9UJA5,O60294,Q08J23,O95163,P05455,Q7Z4G4,Q8TEA1,P57081,Q6P1R4,Q8N1G2,Q9UBP6,Q6P6C2,Q96P11,Q2VPK5,Q86W50 20 +Negative regulation of fat cell differentiation 0.6361656223803822 1.4336521441466783 0.1516715551705045 1.0 0.8598036724603544 5 Q96EB6,Q8N4Q0 2 +Histone h3 k9 modification 0.5104668225759377 1.433617783434593 0.1516813658139664 1.0 0.8598036724603544 13 P26358,Q03164 2 +Carbohydrate phosphorylation 0.5792584094956125 1.4320249171607788 0.1521366904307242 1.0 0.8598036724603544 7 Q13572,P51570,P08237 3 +Nucleoside monophosphate catabolic process 0.6358096482475929 1.4320160873550705 0.1521392173485229 1.0 0.8598036724603544 5 P00492,P00813 2 +Regulation of actin cytoskeleton reorganization 0.532413292998744 1.4316711724858335 0.1522379502454431 1.0 0.8598036724603544 9 Q9Y5K6,Q00535,Q9UQB8 3 +Protein modification by small protein removal 0.3518559163656221 1.431409403884682 0.1523129148275783 1.0 0.8598036724603544 52 Q96K76,Q14694,P51784,O00487,Q04323,P45974,Q96FW1,P19474,Q96RU2,Q99627,P40818,Q9UPT9,Q6GQQ9,P61201,Q7L5N1,Q86UV5,Q92905,Q96BN8,O94966,Q15020,Q93008,O95630,Q01804 23 +Positive regulation of amyloid beta formation 0.6353028617757583 1.4296867573580188 0.1528069426996579 1.0 0.8598036724603544 5 O75116 1 +Multicellular organismal response to stress 0.5784150322551969 1.4278350594200842 0.1533393390497357 1.0 0.8598036724603544 7 P17655 1 +Positive regulation of hydrolase activity 0.354865132056075 1.426965632925214 0.153589800896071 1.0 0.8598036724603544 94 Q9P0J0,Q15555,O14737,O75116,Q96N67,O60343,Q14997,P61289,P09429,P40763,Q96EB6,P21359,Q9Y263,Q14790,Q15257,Q86X10,P31751,P20248,Q14155,P49327,Q9H8V3,Q8TC07,Q15042 23 +Deoxyribose phosphate catabolic process 0.5776897302490769 1.4242313465914729 0.1543795135771268 1.0 0.8598036724603544 7 P00491,P00813,P33316,Q9Y3Z3,Q96DE0 5 +Negative regulation of biomineralization 0.8064596192150683 1.4236457189590137 0.1545490541621101 1.0 0.8598036724603544 3 O75116 1 +Positive regulation of neuron apoptotic process 0.5087086054123773 1.423436192741117 0.1546097468422105 1.0 0.8598036724603544 13 P78362,P21359,Q00535,P49427,P42574 5 +Purine deoxyribonucleotide metabolic process 0.633849229740069 1.4230045736386752 0.154734829404521 1.0 0.8598036724603544 5 P00491,P00813,Q9Y3Z3 3 +Regulation of cilium assembly 0.5074347051977188 1.42232005407363 0.1549333597306659 1.0 0.8598036724603544 17 P50570,Q9NVG8,Q9UHD8,Q15555,Q9NT62,P42858,Q9Y3P9,P50395,Q8TC07,P27695 10 +Negative regulation of protein localization to membrane 0.5537140632120546 1.4202232067119287 0.1555427095689661 1.0 0.8598036724603544 8 Q9HD26,Q00610,Q9ULT8,P41240 4 +Endocrine system development 0.5079269033443056 1.41944791551121 0.1557684714599485 1.0 0.8598036724603544 15 P21359,O00330,Q00534,Q15382,P28482 5 +Regulation of ruffle assembly 0.5535347409598289 1.4192939767337596 0.1558133274295601 1.0 0.8598036724603544 8 Q8NCA5,Q9P258,P35080,P35241,P07737 5 +Dna dealkylation involved in dna repair 0.8053150194087824 1.419212936016373 0.1558369456903017 1.0 0.8598036724603544 3 P29372,Q8N3C0 2 +Non motile cilium assembly 0.5073347797949708 1.4171435748803685 0.1564409547844429 1.0 0.8609528767943164 12 P50570,Q16181,Q9UHD8,Q15555,Q14203,Q15691,Q9UIS9,P27695 8 +Circadian rhythm 0.3812100638761712 1.4145944519057534 0.1571874364344467 1.0 0.8624482459392924 48 Q03164,Q06210,Q05086,O75116,O95352 5 +Regulation of inclusion body assembly 0.5288974655951267 1.412633656145611 0.1577634678098003 1.0 0.8624482459392924 9 P62333,P0DMV9,P49427,Q9UL15,P62195 5 +Negative regulation of cation channel activity 0.598136658738861 1.4122548452960615 0.1578749367819403 1.0 0.8624482459392924 6 P78417,Q06787 2 +Inositol phosphate catabolic process 0.6654638416276473 1.4112225194981205 0.1581790120398434 1.0 0.8624482459392924 4 Q13614,O95861 2 +Dendritic spine morphogenesis 0.5054672083797869 1.4105516517323335 0.158376856175876 1.0 0.8624482459392924 17 O00401,Q00535,P43034,P61160,Q9UQB8,P60953,Q15334,Q05086,O60678 9 +Pyrimidine nucleoside triphosphate metabolic process 0.5054663993039046 1.4093779708792815 0.1587234343615138 1.0 0.8624482459392924 11 Q9BZX2,P15531,P33316,P17812,P27708 5 +Pigment granule organization 0.6307975803674475 1.4089723984167897 0.1588433299011096 1.0 0.8624482459392924 5 O14617,O00203,Q9BXS5 3 +Trophectodermal cell differentiation 0.5972741823059758 1.4081349557241527 0.1590911120133151 1.0 0.8624482459392924 6 Q13618,Q9NZN8,P00813,A5YKK6 4 +Interleukin 1 mediated signaling pathway 0.6297260263508913 1.4040439155537587 0.1603057727835279 1.0 0.8634533694597913 5 Q01804 1 +Establishment of epithelial cell polarity 0.5045225659286635 1.4039869479812936 0.1603227362361319 1.0 0.8634533694597913 11 Q7Z460,P60953,Q9H4A6,Q92614,P26038,P15311,Q8TEW0 7 +Regulation of cyclic nucleotide phosphodiesterase activity 0.8013734123708711 1.4039463119520654 0.1603348374115623 1.0 0.8634533694597913 3 O00170 1 +Regulation of camp dependent protein kinase activity 0.5953735925865794 1.399054410098754 0.1617966674952233 1.0 0.8704713887200068 6 P42858 1 +Cellular response to peptide 0.3200040814089326 1.3981375850850937 0.1620717551875024 1.0 0.8706521367150848 68 P62993,Q00535,Q9UQB8,P41240,O75116,O60343,P14618,P11802,P07814,P48506,Q92974,O00443,P40763,Q96EB6,Q13464,P31751,P20248,Q8TBX8,P07741,Q06124,P14735,P43490,Q99741,Q9Y5X3,O14654,P27695 26 +Cellular response to light stimulus 0.4856113292519582 1.3967804089627442 0.1624796153333036 1.0 0.8721211646970923 27 Q96EB6,P28340,Q96K76,P31751,Q96RU2,Q06787,Q13535,P27544 8 +Polyol catabolic process 0.572078571043656 1.3963389514510225 0.1626124494310343 1.0 0.8721211646970923 7 Q13614,O95861,Q00796 3 +Negative regulation of axonogenesis 0.6278232938124664 1.3952910563175989 0.1629280879793788 1.0 0.8727974062463053 5 Q8N0X7,Q9P265 2 +Response to starvation 0.3863122785216037 1.3948948203174742 0.1630475593174618 1.0 0.8727974062463053 47 Q96EB6,P11310,Q9BY44,Q9P2J5,Q6PKG0,Q9Y4P8,Q9H6U6,Q99570,P85037,P08243,P49327,P30566,P28482,Q92616,O95352,P22681 16 +Response to epidermal growth factor 0.503646708330326 1.3942671386623715 0.1632369503301245 1.0 0.8727974062463053 15 P28482,P19174,Q06124,Q9UQB8 4 +Gliogenesis 0.3483475570451046 1.3941463230630426 0.1632734231694099 1.0 0.8727974062463053 52 P49770,Q00535,P41240,Q14232,P18074,Q15382,P40763,Q8TEW0,P21359,Q8IXJ6,P31751,Q13144,Q06124,P28482,Q9UPY3,P43034,Q96P11,O14744,P46109,Q00534 20 +Hindbrain morphogenesis 0.5016139101243668 1.3917120262129776 0.164009619077373 1.0 0.8729565497843674 10 O15020,Q15058,Q06124 3 +Ribonucleotide catabolic process 0.5245378421811966 1.3890149267494305 0.1648282111120584 1.0 0.8729565497843674 9 P00491,P00813,O00154,Q9BY32,P00492,Q96DE0 6 +Synaptic transmission gabaergic 0.6602143245410502 1.3879513986626908 0.1651518450282016 1.0 0.8730033764894161 4 P21359,P27695 2 +Extracellular matrix disassembly 0.5920416274259377 1.383129576373493 0.1666251383383112 1.0 0.8764188283938381 6 P41440,Q7Z460,A1X283 3 +Regulation of protein localization to endosome 0.6590198767316333 1.3826550090535767 0.1667706733361647 1.0 0.8764188283938381 4 P35241,O75116 2 +Positive regulation of protein localization to early endosome 0.6590198767316333 1.3826550090535767 0.1667706733361647 1.0 0.8764188283938381 4 P35241,O75116 2 +Adherens junction organization 0.5000801224161444 1.3727250616350215 0.1698378350260139 1.0 0.8799042284582946 14 Q07157,Q9P1Y5,P35611,P60953,P41240,Q13177,P35241,Q9H7S9,Q9BTW9,Q96AC1 10 +Protein neddylation 0.5898479704635977 1.372641673411103 0.1698637698321621 1.0 0.8799042284582946 6 Q13564,P61081 2 +Cytoplasmic translational elongation 0.6228978876307103 1.3726255765925726 0.1698687764908237 1.0 0.8799042284582946 5 P05387 1 +Regulation of translational termination 0.6220495966537283 1.368720937936243 0.1710865227988673 1.0 0.8799042284582946 5 Q92900,P63241,P15170,P62495 4 +Cellular response to increased oxygen levels 0.5665084218852723 1.3686307452590794 0.1711147283866687 1.0 0.8799042284582946 7 Q9Y487,O95352 2 +Pyrimidine nucleotide metabolic process 0.4993361225013937 1.3683805681829784 0.1711929834672547 1.0 0.8799042284582946 14 P11172,Q9BZX2,P15531,P33316,P17812,P27708 6 +Exit from mitosis 0.4974952839638672 1.3683307326164644 0.1712085751711405 1.0 0.8799042284582946 10 Q8IXJ6,Q7Z460,O43264,P50748,Q16763 5 +Regulation of vesicle fusion 0.5883478392287732 1.3654680678804278 0.1721059827641178 1.0 0.8831255892306581 6 P31751 1 +Dna strand elongation 0.4959467181465388 1.3636551082103192 0.1726761390832349 1.0 0.8838766331266581 19 P25205,P49005,P18858 3 +Innate immune response activating signal transduction 0.6541218637992711 1.3609319845338044 0.1735351846521742 1.0 0.8838766331266581 4 O43318,Q16512,Q13153 3 +Response to lectin 0.6541218637992711 1.3609319845338044 0.1735351846521742 1.0 0.8838766331266581 4 O43318,Q16512,Q13153 3 +Cellular copper ion homeostasis 0.7902116221416245 1.3607062666655498 0.173606533425521 1.0 0.8838766331266581 3 O75880 1 +Myotube cell development 0.6539384814740432 1.360118553038202 0.1737924108592579 1.0 0.8840013959720587 4 Q08209 1 +Cerebellar cortex morphogenesis 0.5646883148553172 1.359573286054062 0.1739649965289853 1.0 0.8840013959720587 7 O15020,Q15058,Q06124 3 +Methionine metabolic process 0.5870379535858736 1.359203316803431 0.1740821705596162 1.0 0.8840013959720587 6 Q13126 1 +Dna geometric change 0.3199702784980823 1.3576397355047818 0.1745780279596749 1.0 0.8853696880285923 55 P33992,P25205,Q92900,Q12873,P18074,P33993,Q9BRX5,Q9HCK8,Q9H4L7,P38935,P46063,Q92499,P13984,P09429,P27694,Q2NKX8,P33991,P49736,Q13283,O14646,Q14566,Q86WJ1,O15347,Q9Y620,Q8N3C0,P13010,Q9BRT9 27 +Protein kinase a signaling 0.5637899732975611 1.3551022935281951 0.1753849680797334 1.0 0.8868552377160958 7 P35241,P17612,P15311,O00170 4 +Negative regulation of myeloid leukocyte differentiation 0.652193108860079 1.3523762270505348 0.1762549904386516 1.0 0.8868552377160958 4 P21359,Q00534 2 +C terminal protein amino acid modification 0.7876978202448492 1.3509675816564002 0.1767058176106599 1.0 0.8878821182022921 3 O60725,O95352 2 +Regulation of glial cell differentiation 0.4948350734157657 1.3486277751471183 0.1774565546665441 1.0 0.8895997943997951 11 P21359,Q15382 2 +Positive regulation of alpha beta t cell differentiation 0.5621749326479327 1.347063505915343 0.1779597804004751 1.0 0.8901556260564222 7 P00491,P00813,O00203 3 +Dendrite morphogenesis 0.4689010423991864 1.3467803430526477 0.1780509873899769 1.0 0.8901556260564222 30 Q00535,Q9UQB8,P43034,P00492,Q05086,O60678,Q08209,Q14999 8 +Methionine biosynthetic process 0.6168644372024166 1.3448486319182809 0.1786741216139304 1.0 0.8901556260564222 5 Q13126 1 +Positive regulation of activated t cell proliferation 0.7860495328828112 1.3445821325442933 0.1787602165689021 1.0 0.8901556260564222 3 P09429 1 +Actin filament polymerization 0.4185784132113068 1.3430622345751235 0.1792518228627782 1.0 0.8901556260564222 41 P47756,P62993,O15020,O00401,Q9UQB8,P35611,O60610,Q6IBS0,Q9UEY8,P35080,P35241,P07737,P47755,Q9BPX3,P57737 15 +Regulation of dna demethylation 0.6499114223936135 1.3422540234161848 0.1795136453130246 1.0 0.8901556260564222 4 Q01804 1 +Deadenylation dependent decapping of nuclear transcribed mrna 0.7853090474768472 1.3417135600342869 0.1796888886131307 1.0 0.8901556260564222 3 Q86TB9,Q96C86 2 +Peptidyl threonine modification 0.4528852028422072 1.3407692332022347 0.1799953883085563 1.0 0.8901556260564222 34 Q00535,P19784,Q13464,P33981,P53350,Q8IXJ6,Q9Y4B6,Q99986,Q9UHD2,P61086,P27708,P67870,Q04637,O75116,P28482,Q16512,Q8TEW0,Q9Y376 18 +Protein acetylation 0.3061429004056341 1.3398915190422018 0.1802806157485075 1.0 0.8901556260564222 61 Q01105,Q03164,Q9UPT9,Q5VZE5,O14929,O43318,Q9P265,Q14CX7 8 +Interleukin 2 production 0.4923695896110147 1.3392229115588412 0.18049811579453 1.0 0.8901556260564222 10 Q92990,P00491,O43318 3 +Positive regulation of inclusion body assembly 0.6481416296705751 1.3344022131694764 0.1820720751192002 1.0 0.8901556260564222 4 P62195,P49427 2 +Somatic diversification of immune receptors via somatic mutation 0.6145074108030446 1.3339944959228869 0.1822056603810082 1.0 0.8901556260564222 5 Q9UQ84,P52701 2 +Development of primary female sexual characteristics 0.4931221182965515 1.333113091991842 0.1824946936572706 1.0 0.8901556260564222 13 P49770,Q96EB6,Q13144,Q05086,P42574 5 +Pyridine containing compound metabolic process 0.5137005034012025 1.330261279591385 0.1834322000063393 1.0 0.8901556260564222 9 Q9Y617,P00491,P43490,Q13126 4 +Negative regulation of protein modification by small protein conjugation or removal 0.4276927566948196 1.3286138600583988 0.1839753969943873 1.0 0.8901556260564222 39 P62081,P60866,Q9Y263,O60566,Q00535,Q92990,Q04323,O43684,Q96BK5,O95071,P48506,Q9UL15,O60678,Q96FW1,Q13501,P19474,P62841,P31689 18 +Pyrimidine ribonucleoside triphosphate metabolic process 0.5583346215684776 1.327944899575069 0.1841963103561212 1.0 0.8901556260564222 7 P15531,P27708,Q9BZX2,P17812 4 +Circadian regulation of gene expression 0.4886912695463615 1.326207472738169 0.1847709847503216 1.0 0.8901556260564222 20 Q96EB6,Q03164,Q06210,O14744,P43490 5 +Dna dependent dna replication maintenance of fidelity 0.4914781438601799 1.325906217834152 0.1848707631810831 1.0 0.8901556260564222 12 P28340,Q13535,Q7Z7L1 3 +Amp metabolic process 0.4915120502211741 1.3242991928519825 0.1854036984927383 1.0 0.8911118851709153 16 P00813,P30520,Q06203,P00492,P11908,Q01433,P07741,P30566,P31939,O15067 10 +Golgi localization 0.6121831634948103 1.3232902027934828 0.1857388885297881 1.0 0.8918007957270313 5 P60953,P48444,P63104 3 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.5791996054270486 1.3217006759144396 0.1862678435092415 1.0 0.8921644641244106 6 P14635,Q9Y6G9 2 +Response to gonadotropin 0.6118130849209017 1.321585728440647 0.1863061382873558 1.0 0.8921644641244106 5 P48506,P20248 2 +Cellular response to gonadotropin stimulus 0.6118130849209017 1.321585728440647 0.1863061382873558 1.0 0.8921644641244106 5 P48506,P20248 2 +Nucleobase metabolic process 0.481193755320259 1.3202246935323367 0.1867600097645003 1.0 0.892739938683 24 Q9P2T1,Q06203,P11172,P00813,Q9BPU6,P00492,P17812,P07741,P27708,P28482 10 +Suppression of viral release by host 0.6445999128836639 1.318688286926775 0.1872733442243594 1.0 0.892739938683 4 Q14258 1 +Glutamine metabolic process 0.4904859851142366 1.3178324798138157 0.1875597324910853 1.0 0.892739938683 13 Q06203,Q9NQR4,Q06210,P17812,P08243,P27708,O15067 7 +Diencephalon development 0.5776989664874643 1.3145186618744182 0.1886717221502474 1.0 0.892739938683 6 Q15042,O75569 2 +Toxin transport 0.4887610538333281 1.313905183959305 0.1888781139772375 1.0 0.892739938683 11 P49368,P50991,P61923,Q93050,P17987,P35606,P48643 7 +Peptidyl serine dephosphorylation 0.5554929166300807 1.3137952111051177 0.1889151296359723 1.0 0.892739938683 7 Q08209 1 +Protein localization to endosome 0.5554278565100152 1.3134712384935838 0.1890242063579297 1.0 0.892739938683 7 P35241,O75116,P15311 3 +Extracellular matrix assembly 0.777545535980881 1.3116422775629353 0.1896408611750222 1.0 0.8941276415099535 3 Q7Z460,Q96AY3 2 +Negative regulation of jnk cascade 0.6088199324679147 1.3077995360222725 0.1909413116392682 1.0 0.896038939187689 5 P31689,P51452,P43034 3 +Proteasome assembly 0.5540485856277173 1.3066028796694948 0.1913476181245517 1.0 0.896038939187689 7 O95456,Q5VYK3,O75832,Q969U7,Q16186 5 +Response to cold 0.4883899714782597 1.3056834187071384 0.1916602390316262 1.0 0.896038939187689 13 P11310 1 +Regulation of microtubule based process 0.3212312844456828 1.3050796782499343 0.1918657177695437 1.0 0.896038939187689 75 Q9Y295,P27695,Q7Z460,Q15555,O75116,P78559,Q16512,Q14008,Q99996,O14980,O15344,P57076,P16949,Q9BTW9,P29372,Q92974,Q96EB6,Q66K74,O14965,P04350,Q14203,Q14155,Q13153,P43034,P36404,O60610,O75351,Q8TD16,Q14204,Q15691,Q8NI35,P78318 32 +Motor neuron apoptotic process 0.7752131698114688 1.302610052065505 0.1927079242285287 1.0 0.896038939187689 3 P49327 1 +Amino sugar biosynthetic process 0.6406810035842171 1.3013004638461434 0.1931556285333351 1.0 0.896038939187689 4 Q16222,O95394,Q06210 3 +Positive regulation of peptidase activity 0.4076344582524231 1.2998463398713784 0.1936536394712911 1.0 0.8977111539979525 42 Q96EB6,Q14790,Q9P0J0,Q14997,P61289,P20248,P09429,O14737,O75116,P40763 10 +Organelle inheritance 0.4851538912362652 1.2982392626502777 0.1942051302064071 1.0 0.8989906984802976 10 Q99986,P28482,P36507,Q92538 4 +Protein localization to cytoplasmic stress granule 0.6065102769811836 1.2971610154416802 0.1945757912077019 1.0 0.8992592223580661 5 P67809,P05455 2 +Regulation of integrin activation 0.7732349364509892 1.2949502036633298 0.1953374081751007 1.0 0.8998413827969064 3 Q96AC1 1 +Regulation of postsynapse organization 0.4858694612671187 1.2933050010845304 0.1959055916590424 1.0 0.8998413827969064 17 Q9UQB8 1 +Outer ear morphogenesis 0.772297371813111 1.29132024212829 0.1965926543590743 1.0 0.8998413827969064 3 O75569 1 +Positive regulation of translational initiation 0.4853818467570774 1.2908205747859107 0.1967659016179668 1.0 0.8998413827969064 12 Q7Z478,Q13144 2 +Response to acid chemical 0.4766003264263868 1.2908175491178284 0.1967669510337819 1.0 0.8998413827969064 24 Q9P2J5,Q9UQB8,P17655,P48506,O00330,P26358,Q8IWV7,P42574 8 +Positive regulation of protein polymerization 0.4606403581395191 1.2898886331963333 0.1970893279317835 1.0 0.8998413827969064 30 Q14008,Q9Y295,Q99996,Q13153,Q9UQB8,P36404,P07900,Q7Z460,Q15691,Q14203,P35080,P07737,Q16512 13 +Regulation of non motile cilium assembly 0.572532795949275 1.2897902975510085 0.19712347758064 1.0 0.8998413827969064 6 Q9UHD8,P50570,Q15555,P27695 4 +Response to nitric oxide 0.5284850895842909 1.289328586898263 0.197283876711662 1.0 0.8998413827969064 8 Q9GZT9,P20248,Q99707 3 +Regulation of microtubule polymerization 0.4763675799667258 1.2893280774626543 0.1972840537432776 1.0 0.8998413827969064 24 Q14008,Q9Y295,Q99996,Q15691,P36404,Q7Z460,P04350,Q14203,Q14155,P16949,Q9BTW9,Q16512 12 +Sulfur amino acid biosynthetic process 0.5722488710976474 1.2884311681922245 0.1975959148873201 1.0 0.9000059570617852 6 Q13126 1 +Nucleotide sugar metabolic process 0.4851169841186649 1.2867147205822125 0.1981937403097426 1.0 0.9019759705561128 13 O60701,P34949,Q9NR45,Q06210,O95394 5 +Regulation of macrophage migration 0.6369310581457055 1.28466313659437 0.1989100253596247 1.0 0.9022138537333364 4 P30046 1 +Regulation of macrophage chemotaxis 0.6369310581457055 1.28466313659437 0.1989100253596247 1.0 0.9022138537333364 4 P30046 1 +Dna unwinding involved in dna replication 0.4845149074353944 1.2827970776407716 0.1995631782399916 1.0 0.9039201001890528 16 Q9BRX5,P33991,P33992,P49736,P25205,P46063,P27694,P33993,Q9BRT9,Q14566 10 +Sensory organ development 0.3027556047170424 1.2823454508308731 0.1997214906447093 1.0 0.904009826239957 62 Q9BW83,P21359,O95487,P43034,P28482,Q15555,Q8NHU6,P20248,Q92688,O75569,A1X283,Q9Y4P1,Q06124,Q15042,Q15648,P40763,Q15293 17 +Regulation of cell matrix adhesion 0.4707340850242932 1.2814418929755675 0.2000384974111333 1.0 0.9041464483391716 26 P21359,Q13464,Q96AC1,Q9P258,Q7Z460,Q9H6U6,Q9H2G2,P42771,Q00534,P51452,O75116,Q13630 12 +T cell apoptotic process 0.4834507131653693 1.2797084393075773 0.2006476954408076 1.0 0.9041464483391716 12 P62753,P00813,Q9HCL2,P49327 4 +Cell proliferation in forebrain 0.6027026008566048 1.2796224596403707 0.2006779469978834 1.0 0.9041464483391716 5 Q96N67,Q15058 2 +Female sex differentiation 0.4841005927976794 1.2794168170568614 0.20075031491203 1.0 0.9041464483391716 14 Q96EB6,P49770,Q13144,Q05086,P42574 5 +Regulation of cellular response to heat 0.4817372646476437 1.2788350691799304 0.2009551416046784 1.0 0.9041464483391716 10 Q13535 1 +Regulation of t cell receptor signaling pathway 0.4816262262028342 1.2782044944348363 0.2011773318418084 1.0 0.9041464483391716 10 P51452,P15311,P00813,Q96IZ0 4 +Forebrain development 0.2970887968802619 1.2768231523948357 0.2016646897177672 1.0 0.9041464483391716 58 P21359,Q96N67,Q00535,P43034,P27695,P00492,O43776,Q13144,Q15058,Q96P11,A0AVT1,Q00534,Q15042,P42574,P31939,Q9UIS9,O75569,P19784 18 +Regulation of ubiquitin protein ligase activity 0.4833980738878803 1.2753163269785643 0.2021973011083593 1.0 0.9047874373664728 14 P62081,P60866,O00429,P62841,Q16763 5 +Pyridine containing compound catabolic process 0.768048496553855 1.2748731361034944 0.2023541489088858 1.0 0.9047874373664728 3 Q13126 1 +Microtubule anchoring at microtubule organizing center 0.569314868563848 1.27438607428651 0.2025266251315938 1.0 0.9047874373664728 6 Q8TD16,Q9UIS9 2 +Establishment of planar polarity of embryonic epithelium 0.7678373099690978 1.2740557987551402 0.2026436418014778 1.0 0.9047874373664728 3 O95487 1 +Positive regulation of actin filament bundle assembly 0.483116741697661 1.273674317652494 0.2027788619084858 1.0 0.9047874373664728 14 Q96AC1,O75116,Q9Y613,Q16512 4 +Ribonucleoside diphosphate metabolic process 0.3860479540522445 1.2705099545924952 0.2039030392254899 1.0 0.9062160747763284 45 P11172,P85037,P27708,Q96DE0,P31350,P23921,P04075,P09972,P08237,P14618,P17858,P40763,P00338,P36871,P51570,P36404,P00568,Q9UKK9,Q9BW91,P30085,Q01813,P00558,P18669,Q00013 24 +Positive regulation of interleukin 2 production 0.5026090242567387 1.2701086818966367 0.204045919495257 1.0 0.9062160747763284 9 Q92990,O43318 2 +Positive regulation of focal adhesion assembly 0.5679789252076515 1.2679908940690614 0.2048012024281149 1.0 0.907493176000208 6 Q96AC1,Q13464 2 +Megakaryocyte development 0.7657842678320228 1.266110914481135 0.2054733755557678 1.0 0.9087619958423696 3 Q06124 1 +Positive regulation of protein kinase activity 0.3026392977275429 1.26510020678598 0.2058354087875644 1.0 0.9087619958423696 63 Q00535,Q13177,P14174,P41240,P52564,P46940,Q9UER7,Q92796,Q16512,Q9Y376,P36507,O43318,P08238,O75832,Q96AC1,Q99627,Q96EB6,Q13043,Q15334,Q13432,P20248,Q14012,Q99741,Q13153,P07900,Q9Y4R8,Q9H8V3,Q15058,O75909,Q96JP5,P13010,P14635 32 +Positive regulation of jnk cascade 0.567244471010163 1.2644750857012164 0.2060595575901733 1.0 0.9087619958423696 6 O00560,P60953,Q12933,P09429,Q13546 5 +B cell proliferation 0.4799181585245286 1.263361765714064 0.2064591981706784 1.0 0.909284201390026 11 P42574,Q16512,P00813,P17812 4 +Post chaperonin tubulin folding pathway 0.7642609863844199 1.2602171312791477 0.207591044514213 1.0 0.9118786607413504 3 Q9BTW9 1 +Histone h2a k63 linked ubiquitination 0.7639474139872042 1.259003991796149 0.208028890050981 1.0 0.9131167218310378 3 Q96FW1 1 +Purine deoxyribonucleoside triphosphate metabolic process 0.6305256869772864 1.256249868345669 0.2090253914939852 1.0 0.9154790587391366 4 Q96DE0,P00813,Q9Y3Z3 3 +Negative regulation of cytoskeleton organization 0.3713467458176595 1.2554515251945937 0.2093148947938061 1.0 0.9154790587391366 47 P47756,Q7Z460,Q6IBS0,P47755,O15020,P35611,O15344,P16949,Q9BTW9,P35241,P29372,Q92974,Q13045,P04350,Q9UEY8,Q14155,P35080,P07737,Q15691,Q9BPX3 20 +Modified amino acid transport 0.5432517517502234 1.252835906040208 0.2102654314247032 1.0 0.9165531021078456 7 O43772 1 +Cellular response to leucine 0.76179020481367 1.2506593670604178 0.2110587810046147 1.0 0.9177752589054764 3 Q8IWV7 1 +Negative regulation of cell size 0.6288598199985438 1.248862066780514 0.211715527946225 1.0 0.9187961657450816 4 Q96B36 1 +Regulation of smooth muscle contraction 0.5637033987365205 1.247524851988718 0.2122051136099472 1.0 0.9203074927123756 6 Q86TU7 1 +Golgi to endosome transport 0.5630997772212695 1.2446356533643763 0.2132657085475839 1.0 0.9218111373536612 6 Q92538,Q7Z3U7 2 +Tetrapyrrole catabolic process 0.6276675239364387 1.2435750305249669 0.2136560107125107 1.0 0.9218111373536612 4 P53004,P30519 2 +Pancreas development 0.4771041966110963 1.24320267577358 0.2137931569472013 1.0 0.9218111373536612 12 Q00534,Q15382 2 +Regulation of nuclear transcribed mrna poly a tail shortening 0.6275655125002317 1.2431227016502653 0.213822621414411 1.0 0.9218111373536612 4 Q9UIV1,A5YKK6 2 +Positive regulation of plasma membrane bounded cell projection assembly 0.4597623708494275 1.243054462192277 0.2138477648536341 1.0 0.9218111373536612 28 Q9Y2A7,Q8NCA5,Q9NQW6,P60953,Q9H6U6,Q15555,Q6IBS0,Q06787,Q7L576,O00401,Q9UHD8,P61160,Q16658,Q96C92,Q14195,P50570,P42858,P07737,P27695 19 +Nucleoside phosphate catabolic process 0.4772781498355976 1.241956429707436 0.2142526380773191 1.0 0.922445230033418 17 P00491,P00813,O00154,Q9BY32,P00492,Q9UKK9,P33316,Q9Y3Z3,Q9BW91,Q96DE0 10 +Protein localization to nuclear body 0.4761737253126784 1.237852814106661 0.2157706411871935 1.0 0.9254740474965656 12 P49368,Q99832,Q4G0J3,P50991,Q9BUR4,P40227,Q7L2J0,P17987,P48643 9 +T cell receptor signaling pathway 0.4639236650895524 1.23690987689091 0.2161205428218298 1.0 0.926210625737415 26 P49770,Q9NR50,P00813,P19174,P41240,Q13144,Q96IZ0,Q14232,O43318,P46109,P51452,P28482 12 +Long chain fatty acid transport 0.4762968599753882 1.2356256335263929 0.2165977518957187 1.0 0.9273184162359044 13 O43772 1 +Protein localization to lysosome 0.4761345714646748 1.2346861570222605 0.2169473297981041 1.0 0.9273184162359044 13 O75116,P20645 2 +Neuron projection arborization 0.5925012781103172 1.23264421507185 0.2177085330541333 1.0 0.9287474478721098 5 Q9HCE1,Q13464,Q15334 3 +Establishment or maintenance of cell polarity 0.3063352419148649 1.2322034238612205 0.2178731046541904 1.0 0.9288424259163296 68 Q9Y696,P53350,Q7Z460,P60953,Q9H6U6,Q92614,Q96Q89,Q92796,O75116,Q14008,Q96N67,Q13418,P08238,O14777,Q8TEW0,Q99661,P35579,Q13464,Q15334,Q14203,Q92538,P43034,Q03001,P07900,P42858,P46109,O43264,P63172,P15311,Q8NI35 30 +Myotube differentiation 0.4758056693054204 1.231187164821565 0.2182528707692277 1.0 0.929567814087197 16 P17655,Q08209,Q9H4M9 3 +Hippocampus development 0.4751443507607366 1.2292146628145744 0.2189913327778057 1.0 0.930834865706196 17 Q00535,P43034,Q13144,Q15058,A0AVT1,Q00534,P42574 7 +Regulation of microtubule nucleation 0.538210586008711 1.2277378842491538 0.219545380079789 1.0 0.9317117657872452 7 Q14203,Q16512,Q14008,Q14155 4 +Regulation of synaptic transmission gabaergic 0.7554493878769638 1.2261441846468544 0.2201444210156724 1.0 0.9330782436316196 3 P21359,P27695 2 +Respiratory burst 0.6232240129999189 1.2238759815840723 0.2209990155242813 1.0 0.9344475837442068 4 P18669 1 +Regulation of clathrin dependent endocytosis 0.590522184578833 1.2235337152281722 0.2211281780013678 1.0 0.9344475837442068 5 Q13432,O00401,P50570 3 +Phosphatidylinositol 3 phosphate biosynthetic process 0.5904853367498893 1.2233641059387268 0.2211922042109391 1.0 0.9344475837442068 5 Q99570,Q01968,Q96PE3 3 +Response to testosterone 0.4735034211338036 1.2194582371200862 0.2226703176663063 1.0 0.93697385184573 13 O75116,P22681,Q13126 3 +Positive regulation of kinase activity 0.3153133729792869 1.2193502633584383 0.2227112787949341 1.0 0.93697385184573 76 Q05639,Q00535,P60953,P41240,P52564,Q99570,Q9UER7,Q9UNI6,Q92796,Q16512,Q9Y376,P36507,O43318,P08238,O75832,Q96AC1,Q99627,Q96EB6,Q13043,Q15334,Q13432,P20248,Q08AM6,Q92616,Q14012,Q99741,Q13153,P07900,Q9H8V3,Q15058,O75909,Q96JP5,P13010,P14635 34 +Regulation of peptidase activity 0.3226874947410985 1.2191332022282655 0.2227936398313912 1.0 0.93697385184573 82 Q96EB6,O43847,Q15392,Q14790,Q96K76,Q9NR09,Q9P0J0,Q14997,Q04323,P61289,P20248,P09429,O14737,O75116,P30086,P40763 16 +Dna replication initiation 0.4652900527993002 1.2185254764230715 0.2230243494777117 1.0 0.93697385184573 24 P49642,Q9UBD5,P25205,P49427 4 +Voluntary musculoskeletal movement 0.6219900982108195 1.2184073622470055 0.2230692087447705 1.0 0.93697385184573 4 P78559 1 +Negative regulation of programmed necrotic cell death 0.5892478316545576 1.2176682538788313 0.2233500656089098 1.0 0.93697385184573 5 Q92974,Q14790,Q9NX46 3 +Negative regulation of necrotic cell death 0.5892478316545576 1.2176682538788313 0.2233500656089098 1.0 0.93697385184573 5 Q92974,Q14790,Q9NX46 3 +Cellular component maintenance 0.4719089440869589 1.2176177039885376 0.2233692835103349 1.0 0.93697385184573 11 Q07157,Q96QK1,Q15334,Q14203,Q9C0E8,Q96AC1,Q13614 7 +Sperm egg recognition 0.4710668077767225 1.2128110078827783 0.225202085813291 1.0 0.938006809579871 11 P49368,P04075,P50991,Q14157,P17987,P48643 6 +Binding of sperm to zona pellucida 0.4710668077767225 1.2128110078827783 0.225202085813291 1.0 0.938006809579871 11 P49368,P04075,P50991,Q14157,P17987,P48643 6 +Negative regulation of muscle cell differentiation 0.4700953502046948 1.212756913203166 0.2252227731553269 1.0 0.938006809579871 10 P67809,P26358,O75179 3 +Regulation of jun kinase activity 0.5133415162747995 1.2107410337392326 0.225994670661348 1.0 0.9396493794148588 8 O43318,Q16512 2 +Positive regulation of cytoplasmic transport 0.587400659989997 1.2091676166871126 0.2265984561358951 1.0 0.9396493794148588 5 P35241,P15311,Q13614 3 +Positive regulation of early endosome to late endosome transport 0.587400659989997 1.2091676166871126 0.2265984561358951 1.0 0.9396493794148588 5 P35241,P15311,Q13614 3 +Deoxyribonucleoside monophosphate biosynthetic process 0.5869866976188985 1.207262805630225 0.2273309498932945 1.0 0.9414905520009728 5 P33316,P04183,P04818 3 +Positive regulation of meiotic cell cycle 0.7494774559569887 1.2030756197943655 0.2289470589320439 1.0 0.9433948571019314 3 Q9H6S0,P30307 2 +Regulation of cell maturation 0.749477455956988 1.2030756197943624 0.2289470589320452 1.0 0.9433948571019314 3 O14965,Q15058 2 +Fatty acid homeostasis 0.5538698561156044 1.2004703339101512 0.2299567274153833 1.0 0.9453591566156608 6 P28340,Q96EB6 2 +Glyoxylate metabolic process 0.7485403572570679 1.1994578215961182 0.2303499759175653 1.0 0.9453591566156608 3 P48735 1 +Regulation of supramolecular fiber organization 0.3400478220742804 1.1986729122890567 0.2306551547559703 1.0 0.9453591566156608 98 P47756,P62993,Q9Y295,Q9UQB8,Q7Z460,Q6IBS0,O75116,P78559,Q16512,P47755,O15020,O00401,Q14008,Q99996,P35611,O15344,P16949,Q9BTW9,P35241,P29372,Q96AC1,Q92974,P60981,Q66K74,Q13464,Q13045,P04350,Q14203,Q9UEY8,Q14155,Q99471,Q9Y613,Q13153,P36404,P35080,P07737,Q15691,Q9BPX3 38 +Leukocyte apoptotic process 0.4637980733370632 1.197883511151401 0.2309623697862362 1.0 0.9453591566156608 23 Q96EB6,P00813,Q9HCL2,P42574,P42771,P49327,P62753,Q16512,P17987 9 +Cell substrate adhesion 0.3142085669294442 1.1977673351816327 0.2310076070785482 1.0 0.9453591566156608 54 Q00535,Q7Z460,P60953,Q9H6U6,P42771,O75116,Q9UL63,Q13630,Q9HCM4,P51452,Q9BTW9,Q96AC1,P21359,Q13464,Q9P258,Q13043,Q14185,P20248,Q14155,P50570,P36404,Q15058,Q9H2G2,P46109,Q00534 25 +Establishment of cell polarity 0.3583054285459923 1.1963210639303146 0.2315712918896513 1.0 0.9453591566156608 48 P53350,Q7Z460,Q9H6U6,Q92614,Q96Q89,O75116,Q96N67,P08238,Q8TEW0,P35579,Q15334,Q14203,Q92538,P43034,P07900,P42858,P46109,O43264,P63172,P15311,Q8NI35 21 +Locomotory exploration behavior 0.7476858763809997 1.1961595037339436 0.231634320644325 1.0 0.9453591566156608 3 Q05086,Q9HB07 2 +Response to amino acid starvation 0.4691428625728002 1.1942385312810184 0.232384674715639 1.0 0.945620181963202 13 Q9BY44,Q9P2J5,Q6PKG0,P49327,P28482,Q92616 6 +Cellular response to abiotic stimulus 0.3106730602481031 1.1936988100043502 0.2325958061626802 1.0 0.9458896117282332 74 Q96K76,Q15555,Q16539,P29692,Q96KB5,Q06787,O96017,P27544,P30520,P48506,O60921,Q96RU2,Q92974,Q96EB6,P28340,Q14790,Q99439,P31751,P49327,Q13535,P05198,P50570,P45985,Q9H8V3,P42574 25 +Regulation of focal adhesion disassembly 0.746330484200535 1.190928708267046 0.2336815733039903 1.0 0.9466716201222218 3 Q15555 1 +Negative regulation of hemopoiesis 0.466112961994823 1.1901784569632103 0.2339762585908853 1.0 0.9466716201222218 10 P21359,Q9Y3I1,O15347,Q00534,P09429 5 +Negative regulation of t cell apoptotic process 0.7460587720730691 1.1898802624656954 0.2340934571590724 1.0 0.9466716201222218 3 P00813 1 +Neuron apoptotic process 0.3289526663981608 1.1891966994742698 0.234362273007973 1.0 0.9471718612526564 52 P78362,P11413,P55210,P21359,Q01105,Q00535,Q96B36,P51858,P45985,O95630,P49427,P61081,P31751,Q15058,P49327,P42574,Q13564 17 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.6149705590981405 1.1873137327206864 0.2351038932814302 1.0 0.9483772057869388 4 Q96EB6,O75832 2 +Negative regulation of peptidyl threonine phosphorylation 0.7452971036130149 1.1869415286386749 0.2352506850372528 1.0 0.9483772057869388 3 Q8IXJ6,Q8TEW0 2 +Regeneration 0.4316376570396364 1.1862315983250311 0.2355308508552527 1.0 0.9483772057869388 34 O14965,Q99707,P00374,P20248,O14744,Q7Z4V5,Q15648,P31939,Q08209,Q9HAU5,P19784 11 +Regulation of early endosome to late endosome transport 0.4666104143395309 1.1829178419858664 0.2368417097793869 1.0 0.9483772057869388 12 P36507,O60493,O75165,P35241,P28482,Q13614 6 +Erk1 and erk2 cascade 0.4229150801220303 1.182189226151544 0.2371306266039963 1.0 0.9483772057869388 36 P41240,Q99956,Q14152,P63104,P36507,Q96S59,P30046,P09429,P51452,Q96AC1,P49407,Q8IV63,P20248,Q96P70,Q06124,P28482,P18615,P46109,O14744 19 +Positive regulation of dendritic spine development 0.4658495324267316 1.1785519316788842 0.2385766418118968 1.0 0.9518274701138454 12 Q9UQB8 1 +Amino sugar catabolic process 0.742908330845026 1.177727807563757 0.2389051372746653 1.0 0.9524594147470584 3 P26572,P46926 2 +Cellular response to uv 0.4588425484775091 1.1774225554172315 0.239026891581995 1.0 0.9524594147470584 24 P28340,Q96K76,Q96RU2,Q06787,Q13535,P27544 6 +Bergmann glial cell differentiation 0.5801257481284748 1.175707519296366 0.2397117728363966 1.0 0.9544325855604564 5 Q06124 1 +Regulation of toll like receptor signaling pathway 0.5065032870053502 1.1752947288667253 0.2398768226342595 1.0 0.9544325855604564 8 P41440,Q01804 2 +Fc receptor signaling pathway 0.5275593818435715 1.1747494095947983 0.2400949854540246 1.0 0.9544325855604564 7 O43318,P19174,P45985,Q16512 4 +Protein localization to early endosome 0.5796309003152442 1.173432810237402 0.2406222862491511 1.0 0.9558987597980584 5 P35241,O75116 2 +Pyrimidine deoxyribonucleoside triphosphate metabolic process 0.6115272505096134 1.1720734914003963 0.2411675516760789 1.0 0.9560961592620846 4 P33316,Q9H773 2 +Cell matrix adhesion 0.4255633442030627 1.170901122584551 0.2416385238546308 1.0 0.9560961592620846 35 P21359,Q00535,Q96AC1,Q13464,Q9HCM4,Q9P258,Q7Z460,Q9H6U6,Q9H2G2,P42771,Q00534,Q14155,P51452,O75116,Q9UL63,Q13630 16 +Positive regulation of nitric oxide synthase activity 0.7410670325028983 1.1706288172682588 0.2417480088229537 1.0 0.9560961592620846 3 Q8WTV0 1 +Isoprenoid biosynthetic process 0.4626210047641009 1.170395955807773 0.2418416624081616 1.0 0.9560961592620846 10 Q15126,Q13907,P04035,O60678,Q01581,P48449,P53602 7 +Apical protein localization 0.6108585058358851 1.169114672276957 0.2423574332377498 1.0 0.9569673120041096 4 P35241,P54920 2 +Dendritic spine development 0.4507944600393396 1.1663570100267753 0.2434701322152244 1.0 0.9583833340803684 27 P78344,O00401,Q00535,Q9UQB8,P61160,P43034,P60953,A0AVT1,Q15334,Q05086,O60678,Q96HC4,Q06787,Q14012 14 +Cellular modified amino acid biosynthetic process 0.4580393681534379 1.1615981759120184 0.2453987233764563 1.0 0.9604537813703918 23 P11586,P11310,Q8WUX2,O60568,P48506,P00374,P12277,P49419,P31939,Q14353 10 +Ear development 0.4541812275403288 1.159762111082129 0.2461456742211325 1.0 0.9604537813703918 25 Q9BW83,O95487,P43034,P20248,Q9Y4P1,Q06124,P28482,O75569 8 +Positive regulation of g1 s transition of mitotic cell cycle 0.4635493663919564 1.1587212530506932 0.2465698248743726 1.0 0.9604537813703918 16 Q13619,O75179,P35241,Q96DY7,P31350,Q7L2J0,P23921,P27695 8 +Positive regulation of fibroblast proliferation 0.4603228949572387 1.1573860106731368 0.2471146869422327 1.0 0.9604537813703918 10 Q00534,P20248,P14635,Q7Z5K2 4 +Lysosomal microautophagy 0.97223880597015 1.1554186139043825 0.2479190430236744 1.0 0.9604537813703918 2 Q9Y4P1 1 +Positive regulation of gtpase activity 0.4148872247486808 1.1545949821397468 0.2482563224845642 1.0 0.9604537813703918 37 P21359,Q9P2J5,O60343,Q96N67,Q9P258,Q86X10,Q9H8V3,P31751,Q15555,Q14155,Q96AC1,Q8TC07,Q15042 13 +Protein methylation 0.2909325985865342 1.1539726425597807 0.24851138507947 1.0 0.9604537813703918 61 Q96EB6,Q03164,Q8NCA5,Q9BV86,Q86TU7,Q9H993,Q6W2J9,P18615,O14744,P26358,Q5VTR2,Q99873 12 +Regulation of neuron projection arborization 0.7367273079508847 1.1539086641954333 0.2485376166613679 1.0 0.9604537813703918 3 Q9HCE1 1 +Positive regulation of non motile cilium assembly 0.6072281959378626 1.153059291111678 0.2488860491678375 1.0 0.9604537813703918 4 Q9UHD8,Q15555,P27695 3 +Leptin mediated signaling pathway 0.7363019399184085 1.1522707018145348 0.2492098523951589 1.0 0.9604537813703918 3 P40763 1 +Ruffle organization 0.4620199914228271 1.1507745400325688 0.2498250015706857 1.0 0.9604537813703918 14 Q8NCA5,O15357,Q9P258,P35080,P35241,P07737 6 +Histone dephosphorylation 0.6066772130460432 1.1506235632790331 0.2498871347645428 1.0 0.9604537813703918 4 Q99504,P60510 2 +Negative regulation of lymphocyte activation 0.4611258754258456 1.1482009895472136 0.2508856008780253 1.0 0.9604537813703918 18 Q9Y3I1,Q92990,O15347,Q96IZ0,P09429,P42574,Q16512 7 +Telomerase holoenzyme complex assembly 0.5427816728943958 1.1474721210298562 0.2511865489197578 1.0 0.9604537813703918 6 P07900,Q96HR8,Q13535 3 +Positive regulation of ubiquitin protein ligase activity 0.6058535612189488 1.1469829913677183 0.2513886505578493 1.0 0.9606637717746386 4 Q16763 1 +Inclusion body assembly 0.4591911466408574 1.1451222432436965 0.252158522579059 1.0 0.9613847259484728 11 P62333,P0DMV9,P49427,Q9UL15,P62195 5 +Maintenance of dna repeat elements 0.604647659542058 1.1416540658226684 0.2535978411435735 1.0 0.9654946368150666 4 P20585,P52701 2 +Regulation of macroautophagy 0.2873210200760546 1.1413381062452952 0.2537292503643729 1.0 0.9654946368150666 59 Q96EB6,Q00535,Q6PKG0,Q9Y487,Q9UHD2,Q9Y5K8,P42858,Q9Y5X3,O43318,Q15382,P42574,Q15042,P27544 13 +Transcription initiation from rna polymerase ii promoter 0.4491624826593402 1.1407406743652668 0.2539778549129594 1.0 0.9654946368150666 26 P53999,P29083,Q15369,P11802,Q9Y2X0,P35269,P09429,Q86VP6 8 +Dna methylation or demethylation 0.4530422135376017 1.1405362352569433 0.254062965444084 1.0 0.9654946368150666 24 Q03164,O14744,P26358,Q93008,Q96TA1,Q01804,P27695 7 +Positive regulation of reproductive process 0.4997571988488872 1.1403703646378651 0.2541320340199609 1.0 0.9654946368150666 8 O14965,Q9H6S0,P30307 3 +Negative regulation of cell projection organization 0.4416048286825216 1.13969316251105 0.2544141567623548 1.0 0.9660041891727108 29 P35080,Q8N0X7,Q00535,P50570,P10589,P43034,Q9UL15,Q05086,Q9P265,Q08209 10 +Positive regulation of osteoblast differentiation 0.5403245627291199 1.1357410622897068 0.2560649499038634 1.0 0.9673058598299232 6 O00299,Q13418,P20248,Q96AC1 4 +Platelet morphogenesis 0.5196231410211037 1.135325453014058 0.2562389814073751 1.0 0.9673058598299232 7 P42574,P35579,P12814,Q06124 4 +Positive regulation of glucose transmembrane transport 0.5710982105832618 1.1342424357557876 0.2566928680784461 1.0 0.967899682234557 5 P31751,Q06124 2 +Glutamate secretion 0.7301978224106873 1.1287848354868335 0.258988611273633 1.0 0.9721629471630432 3 Q15042 1 +Regulation of gtpase activity 0.2849406421417252 1.1280651581220458 0.2592924023370335 1.0 0.9721629471630432 58 Q9P2J5,Q9H6U6,Q15555,Q96N67,O60343,P16949,Q96AC1,P21359,Q9P258,Q86X10,P31751,Q14155,P05198,P43034,P36404,Q9H8V3,Q8TC07,Q14C86,Q15042 19 +Regulation of cellular carbohydrate metabolic process 0.4397484765453464 1.1272004070157422 0.2596577584525201 1.0 0.9721629471630432 29 Q96EB6,P11310,P31751,P85037,P40763 5 +Pyrimidine nucleoside monophosphate biosynthetic process 0.4968499511966444 1.12533691956987 0.2604462905537055 1.0 0.9721629471630432 8 P11172,P33316,Q9BZX2 3 +Pyrimidine nucleoside monophosphate metabolic process 0.4968499511966444 1.12533691956987 0.2604462905537055 1.0 0.9721629471630432 8 P11172,P33316,Q9BZX2 3 +Cytoplasmic sequestering of nf kappab 0.6008755180643695 1.1249946445358014 0.2605913036760361 1.0 0.9721629471630432 4 O75832,O60826 2 +Negative regulation of mrna 3 end processing 0.5175028115864618 1.1248039981395506 0.2606720998643332 1.0 0.9721629471630432 7 Q5VTR2,P18615,Q6PD62,O75150 4 +T cell activation involved in immune response 0.4961927553200482 1.1219401947492895 0.2618878689896027 1.0 0.9721629471630432 8 P40763,P09429 2 +Cilium movement 0.4750945068018012 1.1211811329169317 0.2622107690070678 1.0 0.9721629471630432 9 P57076 1 +Genitalia development 0.5682009881608778 1.1209518330122867 0.2623083657764535 1.0 0.9721629471630432 5 Q15392 1 +External encapsulating structure organization 0.4511937841057776 1.1185822523189914 0.26331839837757 1.0 0.9721629471630432 23 Q00653,P21359,P41440,Q7Z460,P18074,P20248,A1X283,Q9NPQ8,Q96AY3,P13674,Q9BPX3 11 +Positive regulation of tumor necrosis factor mediated signaling pathway 0.5676725425754445 1.1185286780049546 0.2633412653866558 1.0 0.9721629471630432 5 Q99829,Q13546,P0DMV9,P61086 4 +Terpenoid biosynthetic process 0.5670578561497392 1.1157104821070456 0.2645460822551559 1.0 0.974431308622688 5 O60678,P48449,Q01581 3 +Positive regulation of phosphatase activity 0.5355610070366887 1.113015909695943 0.2657015966242184 1.0 0.975525692301088 6 Q8IV63,P08238,Q15257 3 +Udp n acetylglucosamine biosynthetic process 0.7255897282770882 1.111080752228275 0.2665335920308047 1.0 0.977298437371018 3 O95394,Q06210 2 +Protein localization to phagophore assembly site 0.5350832969831822 1.1107383454435251 0.2666809917529915 1.0 0.977298437371018 6 P50851,Q9Y4P1 2 +Trna wobble base modification 0.5348489074340359 1.109620953638324 0.267162398112406 1.0 0.977298437371018 6 Q2VPK5,O95163 2 +Trna wobble uridine modification 0.5348489074340359 1.109620953638324 0.267162398112406 1.0 0.977298437371018 6 Q2VPK5,O95163 2 +Energy homeostasis 0.4517530343834069 1.1089500044120348 0.2674517504133438 1.0 0.977298437371018 10 Q96EB6,Q01433,P40763 3 +Regulation of intracellular estrogen receptor signaling pathway 0.4548566206003392 1.1084587345318944 0.2676637511164195 1.0 0.977298437371018 17 Q13153,Q9NUQ7,Q969T9,Q92600,P61960,Q15648,Q16512,Q86X55,Q13309,A5YKK6 10 +Aspartate family amino acid biosynthetic process 0.453526224920022 1.1079812576788013 0.2678699102890687 1.0 0.977298437371018 12 P11586,Q99707,Q13126,P08243,Q9NRN7 5 +Cytoplasmic sequestering of transcription factor 0.5343074748417467 1.1070400695042046 0.2682766045954785 1.0 0.9782354179858592 6 O00221,O60826 2 +Regulation of mitotic nuclear division 0.3611155873730726 1.1035191288393862 0.2698017891985125 1.0 0.9824418221245756 46 P33981,P53350,P60953,Q69YH5,Q96Q89,Q96DY7,P50748,Q14999,Q9Y6G9,O60566,O43684,O43683,Q9H900,Q13526,Q15645,O14965,Q13618,Q9UJX4,P30307,Q9UJX5,O14744,O43264,Q969U7,Q15398,P14635 25 +Water soluble vitamin biosynthetic process 0.5643573890562141 1.1033349121518357 0.2698817507383735 1.0 0.9824418221245756 5 Q9Y617,Q969G6,O00764 3 +Dna replication synthesis of rna primer 0.7232005906017351 1.1019113211117413 0.2705002262863714 1.0 0.9832105436805004 3 P49642 1 +Response to uv 0.4034343791953447 1.1014255022814048 0.2707115112544929 1.0 0.9832105436805004 38 Q96EB6,P28340,P55210,P05198,Q96K76,P42574,P18074,O60921,Q96KB5,P39748,P52701,Q96RU2,Q06787,Q13535,P27544 15 +Response to platelet derived growth factor 0.4711813487802165 1.1000790850195714 0.271297665704187 1.0 0.9843023146477092 9 P56192,P46940,P20248,P35241,P22681 5 +Negative regulation of cell substrate junction organization 0.5950519040561193 1.0993074836917454 0.2716339691936125 1.0 0.9849749538481716 4 Q9P258 1 +Regulation of actin filament length 0.3833616571730331 1.0981151961671884 0.2721541905393034 1.0 0.9852520213885806 42 P47756,P62993,O15020,Q9BPX3,Q9UQB8,P35611,Q6IBS0,Q9UEY8,P35080,P35241,P07737,P47755,P60981 13 +Regulation of myelination 0.451623286766638 1.0971121978422522 0.2725923486637387 1.0 0.9852520213885806 12 Q8TEW0,Q8IXJ6,Q15058,Q96P11,Q9UPY3,Q13614 6 +Regulation of cell adhesion mediated by integrin 0.5944630736313589 1.0967126389132515 0.272767029668939 1.0 0.9852520213885806 4 P00813,Q06124 2 +Glucose metabolic process 0.2835636319278853 1.095789827528251 0.2731707612020317 1.0 0.9852618281472972 59 Q96EB6,P11310,P11413,P08237,Q96C23,P31751,P17858,P85037,Q00796 9 +Histone methylation 0.3198691991658905 1.094293842075267 0.2738261251915574 1.0 0.9852618281472972 52 Q03164,Q9BV86,Q6W2J9,P26358,Q86TU7 5 +Positive regulation of stress activated protein kinase signaling cascade 0.4502211323139977 1.0941566008239807 0.2738863018513071 1.0 0.9852618281472972 11 O00560,O15344,P60953,P09429,P29372,Q99873 6 +Regulation of germinal center formation 0.9543283582089556 1.0935457070283865 0.2741542722710619 1.0 0.9852618281472972 2 P00813 1 +Establishment of protein localization to telomere 0.4488495304163092 1.0925733586093045 0.2745811652213779 1.0 0.9852618281472972 10 P49368,P50991,Q9BUR4,P40227,P17987,P48643 6 +Regulation of establishment of protein localization to chromosome 0.4488495304163092 1.0925733586093045 0.2745811652213779 1.0 0.9852618281472972 10 P49368,P50991,Q9BUR4,P40227,P17987,P48643 6 +Positive regulation of establishment of protein localization to telomere 0.4488495304163092 1.0925733586093045 0.2745811652213779 1.0 0.9852618281472972 10 P49368,P50991,Q9BUR4,P40227,P17987,P48643 6 +Meiosis ii cell cycle process 0.5930446675882739 1.0904639787114547 0.275508812410931 1.0 0.9872229224545568 4 O60566,O43683 2 +Female meiotic nuclear division 0.4498033064573316 1.086725408830391 0.2771581812698969 1.0 0.9912391502184204 12 Q6IBW4,Q15645,P33981,P53350,O14965,O95067,Q15003 7 +Immune response regulating cell surface receptor signaling pathway 0.4177185626347038 1.0858544482616823 0.2775433927387163 1.0 0.9920732335189492 34 P49770,Q9NR50,P00813,Q13153,P45985,P19174,P41240,P46379,Q96IZ0,Q13144,Q14232,O43318,P46109,P51452,P28482,Q16512 16 +Positive regulation of glial cell differentiation 0.5091362472221044 1.083347002143089 0.2786544300343552 1.0 0.9932937616980076 7 O14744,Q15382 2 +Regulation of actin filament based process 0.3193115110511733 1.0816740799204947 0.2793973745321558 1.0 0.9933983200015022 89 P47756,P62993,Q00535,Q9UQB8,Q7Z460,P60953,Q9H6U6,P46940,Q6IBS0,O75116,Q16512,P47755,O15020,O00401,Q99996,P35611,P16949,P35241,Q96AC1,P60981,P35579,Q13464,Q13045,Q99439,P60983,Q9UEY8,Q13153,Q9H8V3,Q9Y5K6,P35080,P07737,Q9Y613,P15311,Q9BPX3 34 +Animal organ regeneration 0.449285020932291 1.0805604617285174 0.2798926781802915 1.0 0.9933983200015022 19 O14965,O00330,P20248,O14744,P62841,Q15648,P31939,Q9HAU5,P19784 9 +Negative regulation of translational initiation 0.5077915384920867 1.0766939336125116 0.2816170234249586 1.0 0.9961564775292796 7 Q06787,Q6PKG0 2 +Negative regulation of lipid localization 0.5894719238357794 1.0747373058078464 0.282492356427078 1.0 0.998282409528716 4 P31751 1 +Pre mirna processing 0.5272876491030776 1.0736134851137378 0.2829959511171922 1.0 0.9989802990491692 6 O75569 1 +Regulation of peptidyl lysine acetylation 0.443760646297108 1.0720530322749136 0.2836962130127689 1.0 0.9998300120595804 23 Q01105,Q03164 2 +Response to oxygen levels 0.2976298409017229 1.068509952407554 0.2852905434427186 1.0 1.0 72 Q96EB6,P21359,P00813,Q9Y487,P17655,Q6P6C2,P55786,P20248,P49327,O75116,O95352,P22681 12 +Establishment of golgi localization 0.5879268178271342 1.0679419342770378 0.2855467050834603 1.0 1.0 4 P60953,P63104 2 +Pyrimidine deoxyribonucleotide metabolic process 0.5565578143669622 1.0676470085266307 0.2856797703538178 1.0 1.0 5 P33316,Q9H773 2 +Muscle cell apoptotic process 0.4474387215167774 1.06395942307126 0.2873470817267156 1.0 1.0 16 P42771,P26358,P17655 3 +Regulation of calcium ion transport into cytosol 0.445519593948359 1.062313206632979 0.2880935208888373 1.0 1.0 12 P19174,P42858,P78417,P28161,P27695 5 +Regulation of release of sequestered calcium ion into cytosol 0.445519593948359 1.062313206632979 0.2880935208888373 1.0 1.0 12 P19174,P42858,P78417,P28161,P27695 5 +Hepatic stellate cell activation 0.5866157878653998 1.0621789902596772 0.2881544358300316 1.0 1.0 4 P48506,P48507 2 +Fibroblast activation 0.5866157878653998 1.0621789902596772 0.2881544358300316 1.0 1.0 4 P48506,P48507 2 +Cell differentiation involved in embryonic placenta development 0.711854284861136 1.058464282622667 0.2898438261552758 1.0 1.0 3 Q9ULT8,Q14790 2 +Regulation of nuclear division 0.3435973635468544 1.0580016989719194 0.2900546678361222 1.0 1.0 48 P33981,P53350,Q69YH5,Q96Q89,Q96DY7,P50748,Q14999,Q9Y6G9,O60566,O43684,O43683,Q9H900,Q13526,Q15645,O14965,Q8IXJ6,Q13618,Q9UJX4,P30307,Q9UJX5,O14744,O43264,Q969U7,Q15398,P14635 25 +Negative regulation of tor signaling 0.463154306896583 1.056891272324587 0.2905612120971184 1.0 1.0 9 Q96EB6,Q96B36 2 +Negative regulation of neuron projection development 0.444323593075017 1.054940666394084 0.2914524618863905 1.0 1.0 20 Q8N0X7,Q00535,P43034,P10589,Q05086,Q9P265 6 +Regulation of calcium mediated signaling 0.5033813209486002 1.05489653137864 0.2914726488189205 1.0 1.0 7 P00813 1 +Glutamate secretion neurotransmission 0.9426865671641798 1.0535656125366648 0.2920818398633362 1.0 1.0 2 Q15042 1 +Negative regulation of ion transmembrane transporter activity 0.4425092023944745 1.0504943736698564 0.2934908763894319 1.0 1.0 11 P78417,P28161,Q06787,Q9Y376 4 +Nucleotide phosphorylation 0.4083176538456537 1.0449898176431225 0.2960276756153566 1.0 1.0 35 P51570,P04075,P09972,P08237,P14618,P36404,P15531,P00568,Q01813,P17858,P36871,P85037,P30085,P22392,P18669,P00558,P40763,P00338 18 +Maintenance of dna methylation 0.5824372759856485 1.0438304828050755 0.2965638256705727 1.0 1.0 4 P26358,Q93009,Q9NRZ9 3 +Dna methylation 0.4429494995153075 1.0425174487798778 0.297171840018525 1.0 1.0 19 Q03164 1 +Snrna modification 0.5508826414541514 1.0417396182809893 0.2975324155098249 1.0 1.0 5 Q86W50 1 +Inner ear receptor cell development 0.5006696739106254 1.04151285125687 0.2976375919377498 1.0 1.0 7 Q9BW83,O95487 2 +Cytokinesis 0.2864590771663406 1.0394193213784648 0.298609761932989 1.0 1.0 65 Q9P0V9,P53350,P60953,Q99570,Q96Q89,O75116,Q14999,Q9NR09,Q9UHD8,P16949,P40818,P35579,Q13526,Q13464,P61160,O14965,Q14141,Q13618,Q13432,Q96C92,Q16513,Q99741,O75935,Q9H8V3,Q15058,O75351,O95630,O95239 28 +Regulation of nuclease activity 0.4598666913745536 1.0392475608890943 0.2986896161471506 1.0 1.0 9 Q96EB6,P09429 2 +Vitamin biosynthetic process 0.5200371017783818 1.0391683057609715 0.2987264679374863 1.0 1.0 6 Q9Y617,Q969G6,P14550,O00764 4 +Positive regulation of peptidyl serine phosphorylation 0.4430617464098864 1.038746631456784 0.2989225877110462 1.0 1.0 17 P35080,Q99996,Q96N67,Q13153,Q13043,P07900,Q9UHD2,Q92600,P08238,Q04637,Q16512 11 +Extracellular exosome assembly 0.5812425328554268 1.0385898004818566 0.2989955513666398 1.0 1.0 4 O00560,Q8WUM4,Q99816 3 +Positive regulation of lamellipodium assembly 0.4417300928657494 1.0365291690782883 0.2999553385156268 1.0 1.0 13 P50570,P61160,P60953,Q6IBS0,Q16658,Q7L576 6 +Regulation of histone h2b ubiquitination 0.5494513176254824 1.0352145940207391 0.3005687046971648 1.0 1.0 5 Q5VTR2,Q9NW82,O75150 3 +Mrna modification 0.4420421304441107 1.0352025978955384 0.3005743058023149 1.0 1.0 14 Q8N1G2,Q86W50 2 +Aminoacyl trna metabolism involved in translational fidelity 0.4385725064339963 1.0347813948413522 0.3007710136188564 1.0 1.0 10 P41252,P26640,Q9P2J5 3 +Regulation of neuron projection development 0.2934139782228164 1.0334707901596525 0.3013836332034456 1.0 1.0 71 Q9H4M9,Q9UQB8,Q05086,Q9P265,Q16512,Q08209,Q14999 7 +Positive regulation of protein phosphorylation 0.3467590882870882 1.0327082828345984 0.301740436189208 1.0 1.0 117 O00560,P41440,Q00535,P33981,P53350,P41240,P52564,P46940,Q92600,Q9UER7,Q6PJG6,Q92796,O75116,O96017,Q16512,Q06787,Q9Y376,Q99996,Q96N67,P36507,P51114,P22059,O43318,P08238,O75832,P67870,Q96AC1,Q92974,Q99627,P51116,P49407,Q96EB6,Q13526,Q13043,P31751,P61086,Q15334,Q13432,P20248,P49327,Q06124,Q04637,P28482,Q14012,Q99741,P35080,Q13153,P07900,Q9UHD2,Q9H8V3,Q15058,O75909,P46109,Q13501,Q96JP5,P13010,P14635 57 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.4414361733175111 1.0317161494560991 0.3022051097656062 1.0 1.0 14 P30046,Q9Y6D5,P09429,P40763 4 +Regulation of neurotransmitter transport 0.4416783887258338 1.0306030222412492 0.3027270182465658 1.0 1.0 17 Q4J6C6,P41440,P21359,P35080,Q06787,Q15042 6 +Spindle assembly involved in female meiosis 0.7042599873576674 1.0294886690565337 0.3032501016071451 1.0 1.0 3 O95067 1 +Cytoplasmic microtubule organization 0.4408288207516962 1.027096946391007 0.3043748164142084 1.0 1.0 18 P15311,P43034,Q15154,Q9P1Y5,Q03001,Q7Z460,Q9BSJ2,Q9H2G2,Q14203,Q96CW5,Q14204,Q9UHD1,Q9UIS9 13 +Golgi disassembly 0.547376671317395 1.025763763606212 0.3050029503693863 1.0 1.0 5 Q92538 1 +Regulation of protein acetylation 0.4311686329165161 1.0245465829373093 0.3055771801449867 1.0 1.0 26 Q01105,Q03164 2 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5779569892473013 1.0241916351632014 0.3057447689307835 1.0 1.0 4 Q9UIV1,A5YKK6,P11940 3 +Positive regulation of glucose import 0.5773521708125158 1.021543422422337 0.3069970473721342 1.0 1.0 4 P31751,Q06124 2 +G2 mi transition of meiotic cell cycle 0.7012740213976796 1.0181216948974483 0.3086201264178791 1.0 1.0 3 O95067 1 +Regulation of ras protein signal transduction 0.4148984412250042 1.0180007626106853 0.3086775936603931 1.0 1.0 32 P21359,P41440,Q92538,Q8N6T3,P50570,Q15555,Q15058,P49407,P16949,Q13501,P35241,O95630,Q92974,Q9Y6D5,P22681 15 +Golgi organization 0.2768819319095077 1.0154784214494257 0.3098778275667819 1.0 1.0 59 Q99996,Q92538,Q9UID3,Q7Z392,Q7Z460,P36507,Q99986,Q14746,Q96JB2,P42858,O14744,Q92614,Q14155,P28482,Q8TAT6,Q14999,Q5VU43 17 +Positive regulation of calcium ion transmembrane transport 0.437262680765654 1.0154188100196588 0.3099062303753084 1.0 1.0 12 P11413,P19174,P42858,P78417,P28161,P27695 6 +Positive regulation of protein containing complex assembly 0.2742932342496608 1.0149392596781082 0.310134782268368 1.0 1.0 57 Q14008,Q9Y295,Q99996,Q96AC1,Q9UQB8,Q13153,P36404,Q7Z460,P07900,P35080,Q14203,Q15691,Q04637,Q86VP6,P07737,Q16512,Q9BPX3,Q13535 18 +Regulation of cell cycle g1 s phase transition 0.3876480792129005 1.0148172157123994 0.3101929657261144 1.0 1.0 39 Q9Y3I1,Q13619,Q6Y7W6,P27695,O75179,O95905,Q15058,P42771,P61289,P35241,O96017,Q7L2J0,Q96DY7,P31350,P23921,Q7Z7L1 16 +Mitophagy 0.4380177189914778 1.0120734640434443 0.3115029290417679 1.0 1.0 14 P50851,Q13501,Q9Y4P1,P27544 4 +Asparagine metabolic process 0.6996212854595121 1.0118367332895002 0.3116161233091037 1.0 1.0 3 P08243 1 +Ribonucleoside diphosphate catabolic process 0.6996118244252089 1.011800769240917 0.3116333221130545 1.0 1.0 3 Q96DE0,Q9UKK9 2 +Nucleoside diphosphate catabolic process 0.6996118244252089 1.011800769240917 0.3116333221130545 1.0 1.0 3 Q96DE0,Q9UKK9 2 +Isopentenyl diphosphate biosynthetic process 0.6993132278291873 1.0106658025002626 0.3121764098556423 1.0 1.0 3 P53602,Q15126 2 +Nucleotide excision repair dna gap filling 0.699222724711396 1.0103218315780649 0.3123411248865939 1.0 1.0 3 P28340 1 +Regulation of protein modification by small protein conjugation or removal 0.3151240759412472 1.007108679480059 0.3138825506967577 1.0 1.0 91 P60866,Q00535,Q92990,P53350,Q7Z6Z7,Q9UER7,Q96DY7,Q13309,P62081,O60566,Q9UBT2,P68036,O43684,Q04323,P48506,P08238,O75832,Q96FW1,Q96BK5,P19474,P31689,P49407,Q9Y263,Q13618,O95071,Q9UL15,Q05086,O60678,P15880,O75150,P07900,Q15020,Q5VTR2,Q13501,P62841,Q16763,Q01804 37 +Observational learning 0.9289552238805976 1.0066934640007026 0.3140821039982735 1.0 1.0 2 P21359 1 +Regulation of dna templated transcription initiation 0.4370318359756809 1.006416996754516 0.3142150209203229 1.0 1.0 14 P53999,Q9Y2X0,P11802,P09429,Q86VP6 5 +Negative regulation of plasma membrane bounded cell projection assembly 0.5130567377232261 1.006099845985049 0.3143675427782413 1.0 1.0 6 P47756,P50570,P35080 3 +Cell cell recognition 0.4372530396369024 1.0055134547338915 0.3146496740229527 1.0 1.0 15 P49368,Q99832,P04075,P50991,Q14157,P26038,P17987,P48643 8 +Activation of immune response 0.2966551784589287 1.0044166405638209 0.3151778324669336 1.0 1.0 54 P49770,P00813,Q9NUD5,P41240,Q96IZ0,Q14232,Q16512,P19174,P46379,O43318,P09429,P51452,Q13144,P55212,P28482,Q9NR50,Q13153,P07900,Q9UHD2,P46109 20 +Golgi to plasma membrane transport 0.4297020245457977 1.0035050879310743 0.3156172232900125 1.0 1.0 25 Q4J6C6,P50570,O15027,P41240,Q8TAG9,Q96KP1,Q15334,Q9UJY4,O60826,Q9Y6D5 10 +Macrophage migration 0.511977952048748 1.000998495039349 0.3168275359696337 1.0 1.0 6 P30046 1 +Macrophage chemotaxis 0.511977952048748 1.000998495039349 0.3168275359696337 1.0 1.0 6 P30046 1 +Eye morphogenesis 0.4335908956295125 1.000231823769588 0.3171983317359916 1.0 1.0 11 P21359,P40763,Q8NHU6 3 +Glucose catabolic process 0.433227170866334 0.9981879679512402 0.3181882197790902 1.0 1.0 11 P85037,P17858 2 +Positive regulation of cell death 0.3489102644381811 0.997196606840631 0.3186690876593103 1.0 1.0 122 Q05639,Q00535,P17655,Q99956,Q96IZ0,P42771,Q9UER7,O14737,P62081,P19174,P49427,O00429,P09429,P31689,P78362,P21359,Q96EB6,Q14790,Q15257,Q2TAL8,Q13144,P55212,O00330,P20248,P63241,Q14155,P49327,P62753,O75569,O95352,Q7Z7L1,P50570,P45985,Q9H8V3,P42858,Q13501,P42574 37 +Meiotic spindle assembly 0.5717407131534078 0.9970093762741874 0.3187599587841745 1.0 1.0 4 O95067 1 +Stress granule assembly 0.4359568051376036 0.9969393274949404 0.3187939608595751 1.0 1.0 16 P05198,P26196,Q13283,P62266,O75534,Q14157,Q14204 7 +Artery development 0.4317055145100862 0.9963481837102892 0.3190809999866459 1.0 1.0 10 P21359,Q9ULT8,Q96AY3 3 +Synaptic transmission glutamatergic 0.4914908807538976 0.996330847606562 0.3190894203558829 1.0 1.0 7 P21359,Q15042 2 +Prenylation 0.6953546982765372 0.9956349106870598 0.3194275660068704 1.0 1.0 3 P24386 1 +Protein geranylgeranylation 0.6953546982765372 0.9956349106870598 0.3194275660068704 1.0 1.0 3 P24386 1 +Regulation of leukocyte proliferation 0.422220318573011 0.9941484619157664 0.3201505948332612 1.0 1.0 28 P00813,Q9HCL2,Q92990,Q96IZ0,P09429,P42574,P28482,Q16512 8 +Negative regulation of immune system process 0.3170821162110815 0.9939931224365434 0.3202262157701565 1.0 1.0 51 Q9Y3I1,P00813,Q92990,Q9Y3Z3,Q96IZ0,Q16539,P25786,Q16512,Q14166,O00401,Q13619,P19174,P30046,P09429,P39019,P19474,P28070,P21359,Q9HCL2,Q9UIV1,O15347,Q00534,P42574 23 +Positive regulation of pathway restricted smad protein phosphorylation 0.6948342788892293 0.9936610256816276 0.3203879232264897 1.0 1.0 3 P33981,P67870 2 +Establishment or maintenance of monopolar cell polarity 0.4333221367396338 0.9931248509890166 0.3206491147407224 1.0 1.0 12 Q92538,Q9P1Y5,P60953,Q16658,P26038,P15311,Q8NI35 7 +Negative regulation of cell aging 0.5097458468165899 0.9904518388440048 0.3219533183099154 1.0 1.0 6 Q00534,P67809 2 +Regulation of cartilage development 0.509366206194656 0.9886592163325584 0.3228299031469079 1.0 1.0 6 P20248 1 +Protein autoubiquitination 0.4337058727963987 0.9850513956000267 0.3245988260828389 1.0 1.0 15 O94822,Q05086,P19474,P22681 4 +Ires dependent viral translational initiation 0.4317712464389897 0.9843675894734202 0.324934807781843 1.0 1.0 12 Q9ULC4,Q14152,P41214,P05455 4 +Serine family amino acid biosynthetic process 0.4693914109017555 0.9841452246387052 0.3250441133942447 1.0 1.0 8 P11586,P00374,P49903 3 +Amyloid precursor protein catabolic process 0.4335092594431577 0.983808943686104 0.3252094610356635 1.0 1.0 18 Q15392,Q96P70,P42574,O75116,P27695 5 +Regulation of synaptic vesicle exocytosis 0.4324332940515961 0.9835527158786606 0.3253354836766817 1.0 1.0 13 Q4J6C6,Q06787,Q15042,P35080 4 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.6921469095252133 0.9834765746677526 0.3253729389598705 1.0 1.0 3 P63241,P62081 2 +Regulation of establishment or maintenance of cell polarity 0.4493874239707438 0.983218811345009 0.3254997583709844 1.0 1.0 9 O75116 1 +Regulation of phosphatidylinositol 3 kinase activity 0.6915497163332331 0.9812153101892924 0.3264865757254935 1.0 1.0 3 Q99570,A4D1P6 2 +Positive regulation of lipid kinase activity 0.6915497163332195 0.9812153101892412 0.3264865757255188 1.0 1.0 3 Q99570,Q05639 2 +Negative regulation of phosphoprotein phosphatase activity 0.4289756543179923 0.981117845762384 0.3265346310134114 1.0 1.0 10 O75116 1 +Inflammatory response to antigenic stimulus 0.4301665354827672 0.9810102938158612 0.3265876653331987 1.0 1.0 11 P19174,P28070,P09429,P25786 4 +Negative regulation of cell differentiation 0.2997372228507131 0.9800132470333528 0.3270795797107229 1.0 1.0 80 Q9Y3I1,Q00535,Q8N4Q0,P11413,Q13619,P26196,P26358,P09429,Q96AC1,Q15648,Q99873,Q08209,P40763,Q96EB6,P21359,Q8N0X7,Q9P258,Q8IXJ6,Q9P265,Q06124,P28482,Q9UPY3,Q9UIS9,O15347,Q00534,Q92688,O14744,O75179,P63172,P67809 30 +Regulation of ubiquitin protein transferase activity 0.4287440477671834 0.9787959914344144 0.3276807907594288 1.0 1.0 23 P62081,P60866,O60566,P53350,P68036,O43684,O00429,Q9UL15,P62841,Q16763,P15880 11 +Cellular response to camp 0.5068205353214693 0.9766479759007144 0.328743458952379 1.0 1.0 6 Q99996,P27695 2 +Peripheral nervous system development 0.4311087517851143 0.976033835832178 0.329047697135326 1.0 1.0 13 P21359,Q00535,Q8IXJ6,P31751,Q13418,Q9UPY3,Q8TEW0 7 +Negative regulation of response to external stimulus 0.3408511414126285 0.975996568987426 0.3290661645878643 1.0 1.0 47 P00813,Q9UMX5,Q7Z460,Q9Y3Z3,Q16539,Q96KB5,P25786,Q14166,Q9HCK8,P19174,P30046,P39019,P51452,P19474,P28070,P80303,Q9UIV1,Q8TAT6,Q96BN8 19 +Corpus callosum development 0.5669118321877393 0.9759525269694082 0.3290879903194432 1.0 1.0 4 Q00535,P43034 2 +Dna modification 0.4116579276927387 0.9753210395452224 0.3294010372469786 1.0 1.0 31 Q03164,P27695,O14744,P26358,Q93008,Q8N3C0,P29372,Q96TA1,Q01804 9 +Pyrimidine nucleobase biosynthetic process 0.5063542175874127 0.97444951637667 0.3298333937310138 1.0 1.0 6 P11172,P17812 2 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.4674077801760076 0.9740203671297792 0.3300464266151428 1.0 1.0 8 O43318,Q04206,P52564,Q96BN8 4 +Alcohol catabolic process 0.4287582717787191 0.9731194263596564 0.3304939500886852 1.0 1.0 11 Q8WTV0,O95861,Q15036,Q00796,Q01968,Q13614 6 +Tyrosine phosphorylation of stat protein 0.5354638245527661 0.9716740049219752 0.3312127529723805 1.0 1.0 5 P22059 1 +Deoxyribonucleoside monophosphate catabolic process 0.6890194703165896 0.9716426388153064 0.331228362424012 1.0 1.0 3 P00813 1 +Microtubule anchoring at centrosome 0.5353757927993954 0.9712755438508188 0.331411083869499 1.0 1.0 5 Q14203,Q9UIS9 2 +V d j recombination 0.4667059035491683 0.97044089085638 0.3318267747338774 1.0 1.0 8 P09429,P18858 2 +Response to amyloid beta 0.5655597875838609 0.9700667166696804 0.3320132379251892 1.0 1.0 4 Q00535,P09874 2 +Cellular response to amyloid beta 0.5655597875838609 0.9700667166696804 0.3320132379251892 1.0 1.0 4 Q00535,P09874 2 +Negative regulation of dna replication 0.4268284104046952 0.969159148976412 0.3324657897027048 1.0 1.0 10 Q13535,Q7Z7L1 2 +Translesion synthesis 0.48584220751778 0.968632627077608 0.3327285184050141 1.0 1.0 7 P49005 1 +Response to cocaine 0.4463385541832774 0.966986674077764 0.3335506954104814 1.0 1.0 9 Q05086,P20248,Q00535 3 +Intracellular transport of virus 0.5043912490028336 0.965201298990739 0.3344439964621739 1.0 1.0 6 Q06787 1 +Trna transport 0.5339511985845933 0.9648301229364667 0.3346299054935819 1.0 1.0 5 P67809 1 +Negative regulation of neurotransmitter transport 0.9161194029850754 0.963196797229257 0.3354487720945887 1.0 1.0 2 P21359 1 +Negative regulation of neurotransmitter secretion 0.9161194029850754 0.963196797229257 0.3354487720945887 1.0 1.0 2 P21359 1 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.6867721707972418 0.9631516703807512 0.335471414709017 1.0 1.0 3 Q99873,O60678 2 +Histone arginine methylation 0.6867721707972346 0.9631516703807228 0.3354714147090312 1.0 1.0 3 O14744,Q99873 2 +Regulation of mitotic cell cycle phase transition 0.3214935041959454 0.9625266307146364 0.3357851325997012 1.0 1.0 100 Q9Y3I1,Q96K76,P33981,P53350,P42771,P18074,Q92547,Q7L2J0,Q96DY7,O96017,P50748,P31350,P23921,Q9Y6G9,Q13619,O60566,Q9NXR7,O43684,P11802,O95905,O60921,P61289,Q96BK5,P35241,O43683,Q9H900,Q6Y7W6,Q9P258,Q15645,Q8IXJ6,O14965,Q13618,Q9UJX4,P30307,Q04637,Q13564,Q7Z7L1,Q99741,Q15058,O75351,O43264,O75179,Q969U7,Q15398,P14635,P27695 46 +Positive regulation of ruffle assembly 0.686174977605256 0.9608971179400244 0.3366039000599945 1.0 1.0 3 P07737,Q8NCA5 2 +Pyrimidine nucleobase metabolic process 0.4283045645391963 0.9601418912958384 0.3369838075141318 1.0 1.0 13 P28482,P11172,Q9BPU6,P17812 4 +Protein acylation 0.2796827287422323 0.9596016440847294 0.3372557412923838 1.0 1.0 65 Q01105,Q03164,Q9UPT9,Q5VZE5,O14929,O43318,Q9P265,Q14CX7 8 +Mitochondrial ribosome assembly 0.5322722637637316 0.9572407955042154 0.3384457303759307 1.0 1.0 5 Q567V2 1 +Positive regulation of cholesterol storage 0.9140298507462702 0.956148039203292 0.3389974472684742 1.0 1.0 2 Q9H4M9 1 +Cholesterol storage 0.9140298507462702 0.956148039203292 0.3389974472684742 1.0 1.0 2 Q9H4M9 1 +Negative regulation of response to cytokine stimulus 0.4638818342932159 0.9560552647853462 0.3390443142962613 1.0 1.0 8 Q9UIV1,Q9Y3Z3,Q01804 3 +Synaptic vesicle transport 0.4241386359188711 0.9542067385007168 0.3399790043840442 1.0 1.0 10 Q00535,P50570,Q9Y2T2,O00203,P33176 5 +Retrograde transport vesicle recycling within golgi 0.5607193138813293 0.9490328595942484 0.3426038999223555 1.0 1.0 4 Q96JB2 1 +Positive regulation of interferon beta production 0.4263223138503549 0.9489305579675889 0.3426559315147017 1.0 1.0 13 P41440,Q9BUI4,O14802,Q9UHD2,Q06124 5 +Adaptive immune response 0.3377843484793899 0.9484901605754492 0.3428799795465833 1.0 1.0 47 Q00653,Q96EB6,P00813,P36915,P00492,P41240,O43318,Q96FW1,P09429,Q96FZ2,Q16512,Q9UQ84,P40763 13 +Negative regulation of leukocyte migration 0.4816573870480581 0.9481728697041288 0.3430414563086108 1.0 1.0 7 P00813 1 +Ras protein signal transduction 0.2884686778885537 0.9475960463193652 0.3433351397039463 1.0 1.0 73 P40818,P41440,Q15392,P21359,Q92538,P42771,P26358,P20248,Q13501,P16949,O75116,O95630,Q96RU2,Q9Y6D5,P22681 15 +Peptidyl lysine acetylation 0.2913000610260102 0.9465281117185996 0.3438792908956167 1.0 1.0 54 Q01105,Q03164,Q9UPT9,O14929,O43318,Q9P265 6 +Cell junction maintenance 0.4812921476163289 0.9463898207804006 0.343949795362906 1.0 1.0 7 Q14203,Q07157,Q96AC1,Q15334 4 +Muscle structure development 0.3211255454863205 0.9459762381512714 0.3441607060599425 1.0 1.0 101 P11310,P41440,Q00535,Q14331,Q92990,P17655,P85037,P11413,P26358,Q96PU8,Q7Z4V5,Q15648,Q86TU7,Q08209,Q96EB6,P21359,P61201,Q9H4M9,O75179,P42574,P67809 21 +Camera type eye morphogenesis 0.461746278937113 0.9451954284593946 0.3445591129454119 1.0 1.0 8 P21359,Q8NHU6 2 +Regulation of neurogenesis 0.2746570477064166 0.9444786090199888 0.3449251278772964 1.0 1.0 62 P21359,Q9UQB8,Q15382,Q9P265,Q08209,Q14999 6 +Intracellular distribution of mitochondria 0.9104477611940324 0.9440866607344908 0.3451253652859294 1.0 1.0 2 O75153 1 +Positive regulation of synaptic transmission 0.4267186852354714 0.9430879527492956 0.3456359173244991 1.0 1.0 17 P21359,P41440,Q13501,P28482,Q06787,Q15042,P27695 7 +Cellular response to ether 0.6811458770625329 0.941942466387033 0.3462220966608289 1.0 1.0 3 Q6PKG0 1 +Protein localization to condensed chromosome 0.4240940748424063 0.941174447672018 0.3466154689963281 1.0 1.0 12 Q9H900,Q9P258,O43684,P50748,O43264,Q96DY7 6 +Negative regulation of cell activation 0.4244370770547793 0.9397717295384252 0.3473346628808591 1.0 1.0 21 Q9Y3I1,Q92990,O15347,Q96IZ0,P48506,P09429,P42574,Q16512 8 +Antigen receptor mediated signaling pathway 0.4159233143384187 0.9394958663917364 0.3474762135455373 1.0 1.0 27 P49770,Q9NR50,P00813,P19174,P41240,Q13144,Q96IZ0,Q14232,O43318,P46109,P51452,P28482 12 +Cellular response to radiation 0.3366639970174118 0.9384785849466948 0.3479985172539033 1.0 1.0 47 Q96EB6,P28340,Q96K76,Q9H8V3,P31751,O60921,Q96RU2,Q06787,Q13535,P27544 10 +Telomere maintenance via semi conservative replication 0.5280808352796449 0.938327946707918 0.3480759019855246 1.0 1.0 5 Q92900,P39748 2 +Regulation of behavior 0.4985061261809073 0.9375382663122568 0.3484817495731709 1.0 1.0 6 P40763,Q15334 2 +Positive regulation of histone methylation 0.4240224998987771 0.937279498612217 0.3486148057855966 1.0 1.0 21 P26358,Q03164,Q96EB6,P18615 4 +Eye photoreceptor cell differentiation 0.5578808195877079 0.9367275555119232 0.3488987182034413 1.0 1.0 4 P40763 1 +Negative regulation of histone h3 k9 methylation 0.5274320776497377 0.935405062197608 0.3495795890798883 1.0 1.0 5 P26358 1 +Regulation of small gtpase mediated signal transduction 0.3631100385915597 0.9332498631113983 0.3506909750094884 1.0 1.0 42 P21359,P41440,Q92538,Q8N6T3,P50570,Q86X10,Q9H8V3,Q9Y5K6,Q15555,Q15058,P49407,P16949,Q13501,P35241,O95630,Q92974,Q9Y6D5,P22681 18 +Cytoplasmic translational initiation 0.4228276074994609 0.930102600771608 0.35231796433728 1.0 1.0 21 Q7Z478,Q9NR50,P41214,Q15056,Q9ULC4,O15371,Q04637,Q14240,Q14152 9 +Positive regulation of protein polyubiquitination 0.52614281446073 0.9296001728389486 0.352578137926014 1.0 1.0 5 O00571,P98170,Q13309,O75150 4 +Regulation of viral entry into host cell 0.5260674731185284 0.92926110362389 0.3527537877280746 1.0 1.0 5 P19474,Q14258 2 +Negative regulation of golgi to plasma membrane protein transport 0.6772170797252998 0.9271756738532976 0.3538353309091882 1.0 1.0 3 Q9HD26,P41240 2 +Steroid catabolic process 0.5556293167915438 0.9269831397445494 0.3539352882856974 1.0 1.0 4 Q8WTV0 1 +Regulation of myotube differentiation 0.4961780906488769 0.9266235994900188 0.3541219975271341 1.0 1.0 6 Q96TA1,Q16539 2 +Acylglycerol homeostasis 0.9047761194029852 0.9250489697246688 0.3549404355500811 1.0 1.0 2 Q8WTV0 1 +Homeostasis of number of cells 0.2729571367176072 0.9246031235050448 0.3551723877072781 1.0 1.0 62 P00813,Q16539,O95067,P18074,Q16512,P11413,P62847,P08708,P09429,P39019,Q14157,Q15648,Q99873,P40763,Q6Y7W6,Q9HCL2,P49327,Q06124,P62753,O00203,Q15020,Q00534,P42574 23 +Regulation of nervous system development 0.281479853845997 0.9232772715597776 0.3558627292065854 1.0 1.0 69 P21359,Q13614,Q9UIS9,Q96N67,Q00535,Q8N0X7,Q9UQB8,P43034,Q15058,Q96P11,Q6IBS0,O14744,Q15382,Q9P265,Q08209,Q8TEW0,Q14999,P27695 18 +Positive regulation of dna demethylation 0.6755890556148296 0.9210675642699774 0.3570151533694552 1.0 1.0 3 Q01804 1 +Regulation of adenylate cyclase activity 0.5241693237908109 0.920724319920862 0.357194375602317 1.0 1.0 5 Q99996 1 +Histone threonine phosphorylation 0.5540314080926048 0.9200764684490984 0.3575328003179185 1.0 1.0 4 Q99986,Q16512 2 +Podosome assembly 0.4756002813942787 0.9186611732924924 0.3582728242302297 1.0 1.0 7 A1X283,Q9BPX3,Q16658,P26038 4 +Cellular response to reactive nitrogen species 0.4752638896657524 0.9170259714705123 0.359129030856081 1.0 1.0 7 Q99707,P20248 2 +Regulation of plasma membrane organization 0.5532340648135163 0.9166329665084296 0.3593350033729598 1.0 1.0 4 O00401,P50570 2 +Negative regulation of inflammatory response 0.4205336845611856 0.9163059988078563 0.3595064225494366 1.0 1.0 13 P00813,Q96BN8,P19174,Q16539,P39019,P25786,P28070 7 +Positive regulation of cellular carbohydrate metabolic process 0.5230215289195221 0.9155676391732284 0.3598937109091871 1.0 1.0 5 P31751 1 +Positive regulation of glucose metabolic process 0.5230215289195221 0.9155676391732284 0.3598937109091871 1.0 1.0 5 P31751 1 +Regulation of meiotic cell cycle 0.492874606250605 0.9111652937864418 0.3622082875720731 1.0 1.0 6 Q8IXJ6,Q9H6S0,P30307,Q15645 4 +Cell surface receptor signaling pathway involved in cell cell signaling 0.2888704234717195 0.9108339903294542 0.362382850137154 1.0 1.0 76 P40818,Q04727,Q9UQB8,Q96K76,Q96BN8,Q96C57,O95071,O60493,Q15042,P67870,Q96AC1,Q08209,Q13614,P19784 14 +Regulation of alpha beta t cell activation 0.4182854003600141 0.9086872703050092 0.3635152255020801 1.0 1.0 12 P00491,P00813,O00203,P09429,O14617 5 +Response to heat 0.3644410108861873 0.9058348038533316 0.3650232964774134 1.0 1.0 41 P49770,Q96EB6,P21359,P05198,Q9NR50,P07900,Q13144,Q14232,P48506,O60884,Q9UER7,P08238,Q99615,P31689,Q13535 15 +Regulation of bone resorption 0.6713756140870292 0.905290511716915 0.3653115017273607 1.0 1.0 3 P21359 1 +Regulation of bone remodeling 0.6713756140870292 0.905290511716915 0.3653115017273607 1.0 1.0 3 P21359 1 +Utp biosynthetic process 0.5505715714229058 0.9051486269650342 0.3653866537127179 1.0 1.0 4 P15531,P27708 2 +Positive regulation of actin nucleation 0.5204660890349647 0.904102060532022 0.365941285891886 1.0 1.0 5 Q9Y2A7,O00401,Q9Y6W5,Q7L576 4 +Positive regulation of arp2 3 complex mediated actin nucleation 0.5204660890349647 0.904102060532022 0.365941285891886 1.0 1.0 5 Q9Y2A7,O00401,Q9Y6W5,Q7L576 4 +Negative regulation of g protein coupled receptor signaling pathway 0.472411630314813 0.903178079858202 0.3664313896442663 1.0 1.0 7 P00813,P31946,P50570,P16949 4 +Cellular response to hyperoxia 0.8982089552238826 0.9031010778648996 0.3664722520067385 1.0 1.0 2 O95352 1 +Negative regulation of lipid transport 0.8979104477611961 0.9021059837574458 0.3670005705407071 1.0 1.0 2 P31751 1 +Negative regulation of notch signaling pathway 0.6701223980285215 0.9006068347134301 0.3677973993514518 1.0 1.0 3 Q96TA1 1 +Mechanoreceptor differentiation 0.4330499798529656 0.8966822110917603 0.3698885155477924 1.0 1.0 9 Q9BW83,O95487 2 +Lens development in camera type eye 0.4709811369611155 0.8962447028150585 0.3701220853344749 1.0 1.0 7 Q8NHU6 1 +Response to radiation 0.3061358770853977 0.8938113618652395 0.3714228290613577 1.0 1.0 92 P55210,Q96K76,Q15555,P18074,Q92547,Q06787,P22681,P27544,Q99504,O60921,Q96RU2,P28340,P21359,Q96EB6,P31751,Q13432,P52701,Q13535,Q9H8V3,Q9Y620,Q9NPQ8,P42574 22 +Regulation of osteoblast differentiation 0.4142192470206574 0.8922037304532573 0.3722837430383476 1.0 1.0 11 Q96AC1,Q00534,P20248 3 +Pyrimidine ribonucleoside monophosphate metabolic process 0.5177785570687452 0.892067296449139 0.3723568626613613 1.0 1.0 5 P11172,Q9BZX2 2 +Ump biosynthetic process 0.5177785570687452 0.892067296449139 0.3723568626613613 1.0 1.0 5 P11172,Q9BZX2 2 +Regulation of p38mapk cascade 0.667734039023359 0.8916924783227914 0.3725577862523219 1.0 1.0 3 Q99873 1 +Regulation of response to interferon gamma 0.6673633920573301 0.890310469318089 0.3732992011153691 1.0 1.0 3 Q15648,P08238 2 +Negative regulation of protein dephosphorylation 0.4146967970426625 0.8887102674201911 0.3741588116017342 1.0 1.0 12 O75116,Q15257 2 +Zymogen activation 0.4692573333249122 0.8879005200297391 0.3745942649815279 1.0 1.0 7 Q15392 1 +Sensory perception of light stimulus 0.4163351325966881 0.8874465708385094 0.3748385197374069 1.0 1.0 20 O75569,Q99504,Q00169,Q3SYG4 4 +Basement membrane organization 0.5457069003509549 0.884224526033081 0.3765750212001268 1.0 1.0 4 Q7Z460,Q9NPQ8 2 +Positive regulation of epithelial cell apoptotic process 0.5456000745384524 0.8837659337566812 0.3768225795696822 1.0 1.0 4 P05198,P19174 2 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.89223880597015 0.8832427368911164 0.3771051354955923 1.0 1.0 2 O00170 1 +Alpha beta t cell activation 0.4156443686831867 0.8799330650758748 0.3788955711401411 1.0 1.0 16 P00491,P00813,O00203,P09429,O14617,P40763 6 +Negative regulation of transforming growth factor beta production 0.6641564291324378 0.8783689597358412 0.3797435236610238 1.0 1.0 3 Q9Y5K6 1 +Transforming growth factor beta production 0.6641564291324378 0.8783689597358412 0.3797435236610238 1.0 1.0 3 Q9Y5K6 1 +Peptide catabolic process 0.4102452844398538 0.8775390052179699 0.3801939425186855 1.0 1.0 10 P09960,P55786,Q8WUX2,P14735 4 +Postsynaptic modulation of chemical synaptic transmission 0.5138783895558847 0.8746473798479225 0.381765799453027 1.0 1.0 5 Q08209 1 +Protein dephosphorylation 0.2808595895157089 0.8746072265993241 0.3817876543614091 1.0 1.0 72 P31946,P63151,Q8NCE2,Q69YH5,Q99956,Q96P16,Q9UNI6,O75116,O00743,Q8TF05,Q99504,P08238,O60942,P67870,P51452,O15355,Q08209,Q8IV63,Q13555,Q13526,Q5H9R7,Q15257,P30307,Q06124,Q9ULE6,Q9H2U2,P30154,Q14738,P42858,P60510,Q13614 31 +Negative regulation of mitotic cell cycle 0.269829893609345 0.8740223868515438 0.3821060622812888 1.0 1.0 63 Q9Y3I1,Q96K76,P33981,P53350,Q92547,Q96DY7,P50748,O96017,Q9H6S0,Q9Y6G9,Q9NXR7,O60566,O43684,O60921,Q96BK5,O43683,Q9H900,Q6Y7W6,Q15645,P43246,Q13564,Q7Z7L1,Q99741,O43264,Q969U7,P14635 26 +Mitotic cell cycle phase transition 0.350792338836238 0.8730100804455821 0.38265758327731 1.0 1.0 135 Q9Y3I1,Q00535,Q96K76,P33981,P53350,Q7Z460,Q93034,O95067,P42771,P18074,Q92547,Q7L2J0,P50748,O96017,Q96DY7,P31350,P23921,Q13309,O00743,Q9Y6G9,Q13619,O60566,Q9NXR7,O43684,P49427,P11802,O95905,O60921,P61289,Q96BK5,P35241,Q13617,Q08209,O43683,Q9H900,Q6Y7W6,Q9P258,Q15645,P83731,Q8IXJ6,O14965,Q9Y570,Q13618,Q9UJX4,P20248,P30307,Q04637,P62753,Q13564,Q7Z7L1,Q99741,P50570,P06730,Q07864,Q15058,Q00534,O75351,O43264,O75179,Q969U7,Q15398,P14635,Q16763,P27695 64 +Viral translation 0.4138228870805207 0.8715590387908043 0.3834489847659812 1.0 1.0 15 P41214,P05455,Q9ULC4,O75534,O75821,Q14152 6 +Response to increased oxygen levels 0.4282608342292138 0.8715490658739462 0.3834544274837119 1.0 1.0 9 Q9Y487,O95352 2 +Positive regulation of protein tyrosine kinase activity 0.5125483144608496 0.8687193848858452 0.3850006359160658 1.0 1.0 5 Q92796 1 +Tertiary alcohol metabolic process 0.6612356303754385 0.8675187937532973 0.3856578189570512 1.0 1.0 3 O43488 1 +Aminoglycoside antibiotic metabolic process 0.6612356303754385 0.8675187937532973 0.3856578189570512 1.0 1.0 3 O43488 1 +Polyketide metabolic process 0.6612356303754385 0.8675187937532973 0.3856578189570512 1.0 1.0 3 O43488 1 +Hair cell differentiation 0.4075862483626948 0.862988668839556 0.3881436970055434 1.0 1.0 10 P18074,O95487 2 +Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity 0.8859701492537324 0.862493712302324 0.3884158916510727 1.0 1.0 2 P42858 1 +Protein containing complex remodeling 0.8853731343283585 0.8605232853637603 0.3895006534234129 1.0 1.0 2 Q8WTV0 1 +P body assembly 0.4258898311016643 0.8591517412675204 0.3902568042134149 1.0 1.0 9 P26196,Q9UIV1,Q14204,Q86TB9,Q96F86,A5YKK6 6 +Positive regulation of phosphoprotein phosphatase activity 0.5102999581559668 0.8587140224879525 0.3904983121764709 1.0 1.0 5 Q8IV63,Q15257 2 +Detection of light stimulus 0.5101600848355284 0.8580922232532417 0.3908415412061328 1.0 1.0 5 Q13432,Q15555 2 +Negative regulation of phosphatase activity 0.4078760208489719 0.8572678441806697 0.3912968753736106 1.0 1.0 11 O75116 1 +Histone h3 k4 methylation 0.4061216522291784 0.8562490255543814 0.3918600502265397 1.0 1.0 25 P26358,Q6W2J9,Q03164,Q86TU7 4 +Prosthetic group metabolic process 0.53912783751492 0.8560569296012975 0.3919662906518772 1.0 1.0 4 O96007,Q9NZB8,Q9Y697 3 +Immune response regulating signaling pathway 0.2706735377186195 0.8555448370675559 0.3922495934849794 1.0 1.0 65 P49770,P41440,P00813,Q96BN8,Q9NUD5,P41240,P19174,P46379,Q13144,O43318,Q14258,P09429,O75179,P28482,Q16512,Q8TAT6,Q01804 17 +Trna metabolic process 0.3093883330422524 0.8548852143002182 0.3926146968040169 1.0 1.0 98 Q9P2J5,Q9NPF4,O15091,Q9BV44,P54136,Q7Z2T5,Q9UJA5,P26639,Q92499,O75818,P47897,P41252,Q9NSD9,Q96I59,O43776,O60294,Q08J23,O95163,P05455,Q7Z4G4,Q8TEA1,P57081,Q6P1R4,Q9UBP6,P26640,Q99575,P49589,Q2VPK5,Q9Y285 29 +Uv protection 0.657481418462067 0.8536101930620257 0.3933210088803467 1.0 1.0 3 P18074 1 +Maintenance of cell polarity 0.5087295844952425 0.8517374565976135 0.394359826324079 1.0 1.0 5 Q03001,Q8WUM4 2 +Positive regulation of jun kinase activity 0.479978798688178 0.8511935764717816 0.3946618304703604 1.0 1.0 6 Q16512 1 +Positive regulation of alpha beta t cell activation 0.4242300247999233 0.8504920079905363 0.3950516018764665 1.0 1.0 9 O14617,P00491,P00813,O00203 4 +Lactation 0.4077032378349458 0.8500070944814889 0.3953211419400197 1.0 1.0 12 P61201,P11172,P07741,P15531 4 +B cell apoptotic process 0.4796539323435752 0.8496912272540487 0.3954967770856357 1.0 1.0 6 P00813 1 +Histone h4 acetylation 0.401734106925898 0.8494909113505987 0.3956081853812954 1.0 1.0 27 O14929,Q03164,Q9UPT9 3 +T cell activation 0.2662715891801518 0.8473500113176584 0.3968000586812368 1.0 1.0 62 Q6IBW4,P00813,Q9HCL2,Q14790,P42574,Q92990,P41240,Q96IZ0,P17812,Q00534,Q08209,P09429,Q06124,P62753,P40763 15 +Myeloid cell development 0.4078607850030737 0.8455700357444168 0.3977926472478921 1.0 1.0 13 P11413,P43034,P18074,Q06124,P62753,Q15648 6 +Allantoin metabolic process 0.655279454099674 0.8454726824700779 0.3978469786207355 1.0 1.0 3 P00813 1 +Ribosome associated ubiquitin dependent protein catabolic process 0.507011529718889 0.8441161608322116 0.3986044978340657 1.0 1.0 5 O94822,Q8N3C0 2 +Positive regulation of cyclase activity 0.6548215450724596 0.8437823824279588 0.3987910219935091 1.0 1.0 3 P21359 1 +Spleen development 0.5359644700661574 0.8425706874057866 0.3994685905908044 1.0 1.0 4 Q16512 1 +Negative regulation of ryanodine sensitive calcium release channel activity 0.535928764062853 0.8424186864848872 0.3995536369557468 1.0 1.0 4 P78417 1 +Negative regulation of calcium ion transport into cytosol 0.535928764062853 0.8424186864848872 0.3995536369557468 1.0 1.0 4 P78417 1 +Positive regulation of sequestering of calcium ion 0.535928764062853 0.8424186864848872 0.3995536369557468 1.0 1.0 4 P78417 1 +Dna ligation 0.4413289862056037 0.8423265450593963 0.399605196506537 1.0 1.0 8 P18858 1 +Establishment of spindle orientation 0.4073734319411883 0.8385641843553195 0.401713915974099 1.0 1.0 14 P43034,P53350,Q7Z460,P42858,Q14203,Q15334,O43264,P63172 8 +Regulation of fatty acid transport 0.5055808344685859 0.8377788707464291 0.4021549076609922 1.0 1.0 5 P31751,P52564,P07814 3 +Regulation of chromosome condensation 0.440285629703008 0.8371236903416559 0.4025230453205912 1.0 1.0 8 Q15021,Q15003,Q9NTJ3,Q9BPX3,Q7Z5K2 5 +Regulation of cell substrate adhesion 0.3411867933450992 0.836652524138173 0.4027879125549365 1.0 1.0 44 Q7Z460,P60953,Q9H6U6,P42771,O75116,Q13630,Q9HCM4,P51452,Q9BTW9,Q96AC1,P21359,Q13464,Q9P258,Q13043,Q14185,P20248,Q14155,P50570,P36404,Q9H2G2,P46109,Q00534 22 +Negative regulation of calcium ion transmembrane transport 0.4584865600773896 0.8360550567670821 0.4031239304725409 1.0 1.0 7 P78417,Q06787 2 +Negative regulation of calcium ion transport 0.4584865600773896 0.8360550567670821 0.4031239304725409 1.0 1.0 7 P78417,Q06787 2 +Positive regulation of histone ubiquitination 0.5049508183494604 0.8349909281847464 0.4037228162003385 1.0 1.0 5 Q5VTR2,O75150 2 +Cellular modified amino acid catabolic process 0.4397693097355651 0.8345511808676186 0.4039704590462882 1.0 1.0 8 Q9UHG3,Q8WUX2,Q9NRN7 3 +Negative regulation of viral entry into host cell 0.6522740117980564 0.8343909597470061 0.4040607098523328 1.0 1.0 3 Q14258 1 +Negative regulation of viral life cycle 0.6522740117980564 0.8343909597470061 0.4040607098523328 1.0 1.0 3 Q14258 1 +Demethylation 0.4075210562467298 0.8336121667344586 0.4044995672989175 1.0 1.0 19 Q7LBC6,P27695,Q6P6C2,Q9Y570,Q93008,Q01804 6 +Erythrocyte maturation 0.875820895522389 0.8291370630621211 0.4070268533830665 1.0 1.0 2 P18074 1 +Response to ether 0.5324827184098381 0.8277729782640072 0.4077990805524378 1.0 1.0 4 Q6PKG0 1 +Positive regulation of neuron migration 0.4748531912923129 0.827543498576105 0.4079290779051587 1.0 1.0 6 Q9Y263 1 +Regulation of lipid storage 0.4010121437842095 0.8272112698896383 0.408117325016994 1.0 1.0 10 Q96EB6,Q8WTV0,Q9H4M9 3 +Plasma lipoprotein particle clearance 0.4003222650473611 0.8234740407714805 0.4102384734841928 1.0 1.0 10 Q8WTV0,Q9H4M9 2 +Rna methylation 0.3802373954411239 0.8225380880810599 0.4107707185723681 1.0 1.0 34 Q8N1G2,Q9UBP6,Q9UJA5,O60294,Q08J23,Q86W50,Q9BV44,Q7Z4G4,Q7L2J0,Q7Z2T5,Q8TEA1,P57081 12 +Spindle localization 0.4037076482505705 0.820987152600194 0.4116535861994119 1.0 1.0 22 O00401,P35579,P43034,P53350,Q7Z460,Q15334,Q14203,P42858,P63172,O43264,O14777,Q14204 12 +Regulation of cellular component size 0.2890455881265906 0.8206236639778488 0.4118606642716267 1.0 1.0 83 P47756,P62993,Q9P2J5,Q00535,Q9UQB8,Q6IBS0,Q96ER9,P47755,O15020,P35611,P08238,P35241,P60981,P78344,Q8N0X7,Q9Y666,Q9UEY8,Q9P265,Q96B36,P50570,P43034,P35080,P07737,P15311,Q9BPX3 25 +Erythrocyte development 0.4549425721310611 0.8191162259181294 0.41272010519838 1.0 1.0 7 P62753,P11413,P18074 3 +Postsynapse organization 0.3794958036447242 0.817478375327138 0.4136551022914663 1.0 1.0 34 O15020,O00401,Q00535,Q96QK1,Q9UQB8,P61160,P43034,P60953,Q15334,P46109,Q05086,O60678,Q96HC4,Q13614 14 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4003542277028689 0.8161864250247755 0.414393519698693 1.0 1.0 11 P21359,P30154,Q99504,P0DMV9,P62136,P30153,Q13546 7 +Regulation of carbohydrate metabolic process 0.3726472728848752 0.8157876171037658 0.4146216167349128 1.0 1.0 36 Q96EB6,P11310,P31751,P85037,P40763 5 +Body morphogenesis 0.4538408932172945 0.8138638369739793 0.4157229595550356 1.0 1.0 7 Q15042,Q06124 2 +Negative regulation of erk1 and erk2 cascade 0.4029190100633756 0.8138425001371938 0.4157351843365466 1.0 1.0 14 Q8IV63,P41240,Q99956,Q96S59,Q96P70,P51452,P15311,Q14152 8 +Regulation of long term synaptic potentiation 0.4716758055021773 0.8129424351111348 0.4162510632090064 1.0 1.0 6 P21359 1 +Response to hyperoxia 0.5288764750350902 0.8124993349643934 0.4165051680230118 1.0 1.0 4 O95352 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4712222716467397 0.8108622098488315 0.4174448042195071 1.0 1.0 6 Q96EB6,P61254 2 +Positive regulation of striated muscle cell differentiation 0.4992628131486663 0.8098988016684076 0.4179983406328329 1.0 1.0 5 Q96TA1,Q16539 2 +Artery morphogenesis 0.4528728616133783 0.8092539480256146 0.4183690895530847 1.0 1.0 7 P21359,Q96AY3 2 +Negative regulation of b cell activation 0.470791507094824 0.8088873423197191 0.4185799502878233 1.0 1.0 6 P42574,Q16512,Q96IZ0 3 +Negative regulation of protein containing complex assembly 0.3515320931837089 0.8060256821450669 0.4202280409708816 1.0 1.0 41 P47756,Q6IBS0,P47755,O15020,Q96QK1,P35611,P09429,P16949,Q9BTW9,P35241,Q8IXJ6,P04350,Q9UEY8,Q14155,Q15058,P35080,P07737,Q15691,Q9BPX3 19 +Cytoplasmic sequestering of protein 0.3984642363896843 0.8059286618996806 0.4202839837137195 1.0 1.0 11 P31946,O00221,Q7L5D6,Q9HD26,O60826 5 +Regulation of actomyosin structure organization 0.3975420546886944 0.8038369493331927 0.4214911474132079 1.0 1.0 25 Q96AC1,Q9Y613,Q9H8V3,P16949,P35080,O75116,Q16512 7 +Vesicle cytoskeletal trafficking 0.402418606201765 0.803496640160667 0.4216877379402299 1.0 1.0 18 O00401,P43034,Q9Y2T2,O00203,P42858,P33176,Q14204,P27695 8 +Positive regulation of cytokine production 0.2707957322526703 0.8022333792694326 0.42241797131721 1.0 1.0 69 Q96EB6,P41440,Q9BUI4,O14802,Q14790,Q92990,Q9NUD5,Q9UHD2,O43318,P30046,P09429,P40763,Q06124,O75116,Q9NW08,Q9Y6D5 16 +Natural killer cell activation 0.4330256061004763 0.8010913696936945 0.4230787520879726 1.0 1.0 8 P46379,Q14790 2 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.4971450556457639 0.8005940742165868 0.4233666824008808 1.0 1.0 5 Q9Y6G9 1 +Regulation of cation channel activity 0.401558856618037 0.8003938711447516 0.4234826308348127 1.0 1.0 16 P42858,P78417,P28161,Q06787,P27695 5 +Cellular response to interferon alpha 0.6426849179564975 0.7992385653808165 0.4241520938722622 1.0 1.0 3 P10155 1 +Tetrahydrofolate biosynthetic process 0.4967180437388082 0.7987204931493298 0.42445250115852 1.0 1.0 5 P00374,P31939 2 +Regulation of lymphocyte differentiation 0.4013513864457187 0.7978076868868846 0.4249820998401641 1.0 1.0 17 P00491,Q9Y3I1,P00813,O15347,O00203,P09429 6 +Collagen fibril organization 0.4323216180590893 0.7976140912641121 0.4250944711754123 1.0 1.0 8 P21359,P13674,Q96AY3 3 +Protein targeting to lysosome 0.4322663240798061 0.79734110264795 0.425252955150186 1.0 1.0 8 P20645 1 +Negative regulation of smooth muscle cell differentiation 0.524680073654179 0.7947978560768985 0.4267310983170376 1.0 1.0 4 P26358 1 +Positive regulation of phospholipase activity 0.4497917943176845 0.7946155512321388 0.4268371694072301 1.0 1.0 7 Q9Y263 1 +Establishment or maintenance of bipolar cell polarity 0.4003630514744834 0.7942739303822339 0.4270359772846999 1.0 1.0 20 Q9Y696,Q8WUM4,P60953,Q13418,Q16658,P26038,Q92796,P15311,Q8NI35,Q8TEW0 10 +Pyrimidine deoxyribonucleotide biosynthetic process 0.5243667692709699 0.7934794656834391 0.4274985284066566 1.0 1.0 4 P33316 1 +Protein localization to vacuole 0.4005638727787871 0.79297485211334 0.4277924746512918 1.0 1.0 18 O75116,P20645 2 +Regulation of amyloid beta clearance 0.4953689871526824 0.7928070655799377 0.4278902393098758 1.0 1.0 5 P04035,Q16850,Q13464,Q13547 4 +Response to alkaloid 0.3969126979229626 0.7924174872446873 0.4281172861856097 1.0 1.0 24 P55210,P63151,Q00535,P55212,O00330,P20248,Q05086,P42574,P28161 9 +Regulation of synaptic transmission glutamatergic 0.5239632367584147 0.7917820644532815 0.428487762014784 1.0 1.0 4 Q15042 1 +Photoreceptor cell differentiation 0.49485135779492 0.7905404505050532 0.4292122085322414 1.0 1.0 5 P40763 1 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.6398925052254343 0.7890639080290351 0.4300746552244041 1.0 1.0 3 Q8WUM4,O75351 2 +Negative regulation of neuron death 0.324995798636904 0.7887051042526054 0.4302843839512249 1.0 1.0 46 Q96EB6,P62191,Q9Y3I1,Q9UGN5,Q9UMX5,Q00535,Q96QK1,Q01105,Q13464,P51858,P45985,Q15058,P48506,P08238,P48507,Q04637,O95630,P22681 18 +Purine deoxyribonucleoside monophosphate metabolic process 0.6393478826434897 0.7870828878143283 0.4312333459896869 1.0 1.0 3 P00813 1 +Damp metabolic process 0.6393478826434897 0.7870828878143283 0.4312333459896869 1.0 1.0 3 P00813 1 +Protein autophosphorylation 0.3612499054268295 0.7866505799683545 0.4314864415071402 1.0 1.0 38 P49761,P05198,Q00535,Q13153,Q16512,P33981,Q13043,O14965,P41240,P36507,Q99986,Q9NYV4,Q9H2G2,P27708,P17612,O96017,Q13535 17 +Body fluid secretion 0.398323589980264 0.7849266785127083 0.4324965590724492 1.0 1.0 15 P11172,P00813,P15531,P07741,P61201 5 +Regulation of neuron migration 0.4292470885406927 0.7824644398042074 0.433941675896488 1.0 1.0 8 Q9Y263,Q96Q89 2 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.4110545214088704 0.7823636619551544 0.434000882989773 1.0 1.0 9 Q9Y263,Q9H9H4,Q99816,O75351,Q9UN37 5 +Face development 0.4109678606945786 0.781919468236679 0.4342619029030232 1.0 1.0 9 Q15042,Q06124 2 +Insulin receptor signaling pathway 0.3923433557137701 0.7810342663329635 0.4347823412057352 1.0 1.0 26 Q96EB6,Q9UQB8,P31751,P11802,Q9Y5X3,Q06124,P43490 7 +Regulation of fibroblast migration 0.4461334148013482 0.7773042985156461 0.436979259580815 1.0 1.0 7 Q14155 1 +Positive regulation of muscle cell apoptotic process 0.3917254761282235 0.7772040590388914 0.4370383878246087 1.0 1.0 10 P17655 1 +Pigment granule maturation 0.6366079426694515 0.777133828034688 0.4370798177200659 1.0 1.0 3 O14617,Q9BXS5 2 +Pigment accumulation 0.6366079426694515 0.777133828034688 0.4370798177200659 1.0 1.0 3 O14617,Q9BXS5 2 +Gland development 0.2755091704171664 0.7753521082569302 0.4381316262448949 1.0 1.0 75 P11310,P21359,P11172,P00813,O14965,P15531,P31751,O95067,Q05086,P07741,P49327,P61201,P28482,Q9HAU5,P19784 15 +Cellular response to leucine starvation 0.5194754765994418 0.7729570133162971 0.4395478213627164 1.0 1.0 4 Q92616 1 +Negative regulation of peptide secretion 0.4627962219035411 0.7724030078163207 0.4398757729695282 1.0 1.0 6 Q08209,P17858 2 +Negative regulation of hormone secretion 0.4627962219035411 0.7724030078163207 0.4398757729695282 1.0 1.0 6 Q08209,P17858 2 +Brain morphogenesis 0.4449850744906065 0.7718867244473592 0.4401815207683062 1.0 1.0 7 Q9UID3,P21359,P43034 3 +Cell projection assembly 0.3058352219978229 0.7699627153534839 0.4413220098639725 1.0 1.0 102 O00560,P47756,Q9Y2A7,Q8NCA5,P15311,P27695,Q9NQW6,P60953,Q9Y5K8,Q9H6U6,Q9H4A6,P50395,Q9NT62,Q6IBS0,Q15555,P36405,Q06787,Q3SYG4,Q7L576,Q9BZH6,O00401,Q16181,Q15154,P57076,Q9UHD8,P51114,Q9Y3P9,P10155,P35241,P51116,Q13464,Q9P258,O15357,P61160,Q14141,Q14203,Q14155,Q16658,Q96C92,Q86Y56,Q15019,Q9UIS9,Q14195,Q92538,P50570,Q9H4M9,Q9Y5K6,Q9NVG8,P42858,P35080,Q01968,P07737,Q15691,Q8TC07,Q9BPX3,Q9Y4G8 56 +Water soluble vitamin metabolic process 0.3929012841362085 0.7685110091673697 0.4421836526299296 1.0 1.0 24 Q9Y617,Q9H2D1,P41440,P11166,Q8NFF5,Q99707,O00764,P48506,P00374,Q96EY8,Q8IYS1,P78417,Q969G6,Q9NRN7 14 +Regulation of reproductive process 0.3959650968593199 0.7670269983423508 0.4430654635937565 1.0 1.0 18 P35579,P00813,Q15645,P33981,Q8IXJ6,O14965,P30307,Q9H6S0 8 +Rrna base methylation 0.4615619678947646 0.7668010798150129 0.4431997942723273 1.0 1.0 6 Q86W50 1 +Lymphocyte apoptotic process 0.3952798727544859 0.7654733044093701 0.4439897569587132 1.0 1.0 16 P00813,Q9HCL2,P49327,P62753,Q16512,P24390 6 +Regulation of neurotransmitter receptor activity 0.6327261869214605 0.7630891973788679 0.4454102020643482 1.0 1.0 3 Q99996,Q15334 2 +Histone h2a ubiquitination 0.4252884288393524 0.7630497900604694 0.4454337025871178 1.0 1.0 8 Q6W2J9,Q96FW1 2 +Cytoplasm organization 0.6322137290321728 0.7612396005450548 0.4465139691911806 1.0 1.0 3 Q8NHU6 1 +Nuclear migration 0.3933246322609241 0.7611532485653273 0.4465655386895046 1.0 1.0 14 Q96N67,P43034,Q9UH99,Q14204,Q9Y613,Q9UIS9 6 +Regulation of protein tyrosine kinase activity 0.3901224900604176 0.7609981005131646 0.4466582017947813 1.0 1.0 11 P22681,Q92796 2 +Positive regulation of lymphocyte differentiation 0.3900675640862234 0.7607042205967409 0.4468337533282751 1.0 1.0 11 P00491,P00813,O00203 3 +Monosaccharide biosynthetic process 0.3888556670673697 0.7598713434624536 0.4473314924126859 1.0 1.0 26 Q96EB6,P11310,Q00796 3 +Regulation of cellular protein catabolic process 0.2902501506967808 0.7592837221753891 0.4476828527496348 1.0 1.0 89 O00560,O75925,P62191,P15311,P43686,P62333,Q92990,P53350,P68400,O60826,Q96KB5,P62829,P78559,Q06787,O00487,P62081,Q96QK1,O14980,Q04323,P46379,P48506,P45974,P61289,P08238,O75832,O43765,P35241,Q9Y5A7,P19784,Q9ULT8,Q8IXJ6,O14965,P61086,Q9UL15,Q05086,O95376,Q9Y5K5,Q9NRR5,Q9Y4X5,O94966,O75150,P07900,Q9BW61,A4D1P6,P17612,P62195 46 +Monosaccharide catabolic process 0.3936303398242184 0.7590949254419314 0.4477957745315952 1.0 1.0 15 P51570,P08237,Q9UKK9,Q96C23,P17858,P85037 6 +Negative regulation of striated muscle cell differentiation 0.4875605975623738 0.7587599181802311 0.4479961865697204 1.0 1.0 5 P67809 1 +Maintenance of synapse structure 0.5159908261094673 0.7584080626859928 0.4482067326153891 1.0 1.0 4 Q15334 1 +Mirna metabolic process 0.3881948713865381 0.7583748606688357 0.4482266031999338 1.0 1.0 10 Q9HAV4 1 +Positive regulation of microtubule nucleation 0.4596593859151392 0.7581825292334752 0.4483417186417511 1.0 1.0 6 Q14203,Q16512,Q14008 3 +Meiotic spindle organization 0.4419743796367804 0.7577215067587442 0.4486177211094819 1.0 1.0 7 O14965,P35579,O14777,O95067 4 +Negative regulation of receptor mediated endocytosis 0.4239751410337714 0.7566327177410913 0.4492699342435531 1.0 1.0 8 Q13432,Q13614,Q15334 3 +Positive regulation of mitotic cell cycle phase transition 0.3605362786074919 0.7555297496674597 0.4499311890708908 1.0 1.0 37 Q99741,Q13619,Q9P258,P27695,Q13618,P11802,Q9UJX4,O75351,P35241,P30307,Q15398,Q04637,Q7L2J0,Q96DY7,P14635,P31350,P23921,O75179 18 +Rescue of stalled ribosome 0.4590335823283558 0.7553522021786592 0.4500376844109 1.0 1.0 6 O94822,Q86UK7,O60524,Q8N3C0 4 +Positive regulation of microtubule polymerization or depolymerization 0.3935333866050142 0.7533914983710098 0.4512146900606661 1.0 1.0 18 Q14008,Q9Y295,Q99996,Q16512,P36404,Q7Z460,Q14203,Q15691 8 +Liver morphogenesis 0.6297402209614776 0.7523272714021976 0.4518542715016316 1.0 1.0 3 Q15648,Q13618 2 +Histone h4 r3 methylation 0.8519402985074622 0.7519454561939761 0.452083860519862 1.0 1.0 2 Q99873 1 +Positive regulation of cell cycle checkpoint 0.4582472204951886 0.751798935965315 0.4521719819935876 1.0 1.0 6 Q9Y6G9 1 +Protein localization to synapse 0.3869547697854363 0.7517869758930956 0.4521791755530744 1.0 1.0 10 Q00535,Q9UQB8,Q15334,P33176,P78559 5 +Regulation of muscle hypertrophy 0.3898699412003006 0.7471875188332682 0.4549503769961216 1.0 1.0 13 O75116,Q08209 2 +Regulation of heart rate 0.3873118332609664 0.7459947590161325 0.4556705810152659 1.0 1.0 11 P00813 1 +Regulation of deoxyribonuclease activity 0.4569518893600798 0.7459537500280781 0.4556953541828861 1.0 1.0 6 P09429 1 +Adipose tissue development 0.3885499211726902 0.7458661414458219 0.4557482802927732 1.0 1.0 12 Q96EB6,Q8N0X7,P11802,A1X283,P43490 5 +Alditol metabolic process 0.4392837344758216 0.7451108447164881 0.4562047136856664 1.0 1.0 7 P51570,Q00796 2 +Positive regulation of ryanodine sensitive calcium release channel activity 0.8495522388059715 0.7443363772890215 0.4566729989318294 1.0 1.0 2 P78417 1 +Regulation of skeletal muscle contraction by calcium ion signaling 0.8495522388059715 0.7443363772890215 0.4566729989318294 1.0 1.0 2 P78417 1 +Cell morphogenesis involved in neuron differentiation 0.2977788605608348 0.7438095449344799 0.4569917048342558 1.0 1.0 97 P41440,Q00535,Q9UQB8,Q6IBS0,P78559,Q16512,Q14999,O00401,Q9BPU6,Q96N67,P00492,P16949,Q9BTW9,Q96TA1,Q08209,Q66K74,Q8N0X7,Q05086,O60678,Q9P265,Q06124,O95487,P50570,P43034,Q93008 25 +Mitotic cytokinesis 0.3622544022294018 0.7436282345704723 0.4571014169751044 1.0 1.0 36 Q9H8V3,Q13432,P16949,Q96Q89,O75116,Q14999,P40818 7 +Regulation of small molecule metabolic process 0.2911423664297788 0.7430770863878101 0.4574350113337542 1.0 1.0 51 P11310,P85037 2 +Regulation of trans synaptic signaling 0.2520233514923733 0.74195889785233 0.4581122389405745 1.0 1.0 58 Q4J6C6,P41440,P21359,Q99996,Q9UQB8,P27695,P28482,Q9UBB6,Q13501,P35080,Q15042,P78559,Q06787,Q08209,Q13614,P40818 16 +Regulation of phagocytosis 0.3897489917145908 0.7417319157768141 0.4582497786119328 1.0 1.0 14 Q8WTV0,P50570,P41240,Q9NT62,Q92614,O60493,P09429 7 +Regulation of microtubule based movement 0.4835096656034188 0.7412249152304893 0.4585570789604796 1.0 1.0 5 P57076 1 +Low density lipoprotein particle clearance 0.4027544751341518 0.7400807603532712 0.4592509921424299 1.0 1.0 9 Q8WTV0,Q9H4M9 2 +Regulation of protein localization to cilium 0.5115578587157091 0.7399906451727023 0.4593056706579355 1.0 1.0 4 P50395 1 +Negative regulation of endocytosis 0.3845574426047884 0.7390908900092773 0.4598518083047049 1.0 1.0 10 Q13432,Q13614,Q15334 3 +Synaptic vesicle localization 0.3858529170385602 0.7382358127781877 0.4603711638223657 1.0 1.0 11 Q00535,P50570,Q9Y2T2,O00203,P33176 5 +Negative regulation of ubiquitin protein ligase activity 0.4022420882769819 0.7374885475674242 0.460825305173141 1.0 1.0 9 P62081,P60866 2 +Regulation of amyloid precursor protein catabolic process 0.3901076345788911 0.7369931917084582 0.4611264896641833 1.0 1.0 16 P42574,O75116,Q96P70,P27695 4 +Regulation of proteasomal protein catabolic process 0.2669842152578655 0.7342119455562137 0.4628195741643985 1.0 1.0 71 O00560,P62191,P43686,P53350,Q92990,Q96KB5,P78559,Q06787,O00487,O14980,Q04323,P46379,P48506,P61289,P08238,O75832,P45974,Q9Y5A7,Q9ULT8,O14965,Q8IXJ6,P61086,Q9UL15,O95376,Q9Y5K5,Q9NRR5,O94966,O75150,Q9BW61,P17612,P62195 31 +Nucleus localization 0.3889012785587271 0.7332815189556592 0.4633867445080919 1.0 1.0 15 Q96N67,P43034,Q9UH99,Q14204,Q9Y613,Q9UIS9 6 +Positive regulation of neurotransmitter secretion 0.8459701492537346 0.7329632426174149 0.4635808485718589 1.0 1.0 2 Q15042 1 +Positive regulation of toll like receptor signaling pathway 0.4810819719024594 0.7307610697258381 0.4649251063146478 1.0 1.0 5 P41440 1 +Digestive system development 0.3836911380614334 0.7267762195079337 0.4673630530752488 1.0 1.0 11 Q9HCK8,P00813,Q9HCM4,O00330,P46109 5 +Regulation of endodeoxyribonuclease activity 0.5076673461630538 0.7239149631028216 0.4691179431213301 1.0 1.0 4 P09429 1 +Response to ionizing radiation 0.3221884023335239 0.7234742396159087 0.4693885749605742 1.0 1.0 45 P62993,Q16539,Q92547,P29692,Q6PJG6,O96017,P22681,Q9NXR7,Q99504,O60921,Q96RU2,Q96EB6,P43246,Q13535,P50570,Q9H8V3,Q9Y620,P42574,P13010 19 +Replicative senescence 0.4790810730907614 0.7221629442578991 0.4701943027903148 1.0 1.0 5 P42771,Q13535 2 +Layer formation in cerebral cortex 0.6210158269730911 0.7211016553223655 0.4708469726731445 1.0 1.0 3 Q00535 1 +Mitochondrial rna processing 0.3823227882342919 0.7195462615150375 0.4718044091165156 1.0 1.0 11 O15091 1 +Negative regulation of type i interferon mediated signaling pathway 0.4784572342019946 0.7194871629412946 0.4718408089168342 1.0 1.0 5 Q9UIV1,Q9Y3Z3 2 +Regulation of lamellipodium assembly 0.3868282151066369 0.7190797052326015 0.4720918110555028 1.0 1.0 16 P47756,P50570,P61160,P60953,Q6IBS0,Q16658,Q7L576 7 +Positive regulation of leukocyte apoptotic process 0.4782433262958808 0.7185702119298463 0.4724057726567552 1.0 1.0 5 P42771 1 +Regulation of ubiquitin dependent protein catabolic process 0.254678135697396 0.7175763509959856 0.4730185436606733 1.0 1.0 62 O00560,O75925,P53350,Q92990,P68400,O60826,Q96KB5,P62829,P78559,P62081,O14980,Q04323,P46379,P48506,P45974,P08238,O75832,O43765,Q9Y5A7,P19784,Q9ULT8,O14965,Q8IXJ6,P61086,Q9UL15,Q05086,O95376,Q9Y5K5,Q9NRR5,Q9Y4X5,Q9BW61 31 +Tissue remodeling 0.386204179670843 0.7156842359161334 0.4741863468632545 1.0 1.0 16 O75116,P21359,Q08209,Q9UBB6 4 +Regulation of cardiac muscle cell proliferation 0.5053379599574658 0.7143309912269911 0.4750225329059845 1.0 1.0 4 P06493,Q16539 2 +Positive regulation of cardiac muscle cell proliferation 0.5053379599574658 0.7143309912269911 0.4750225329059845 1.0 1.0 4 P06493,Q16539 2 +Response to nicotine 0.4151752371105443 0.7139615298229316 0.475250968083778 1.0 1.0 8 P42574,P28482 2 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.3862134095049697 0.7137337824750741 0.4753918125632672 1.0 1.0 17 Q96EB6,P62081,P46379,P55212,Q96RU2 5 +Intracellular receptor signaling pathway 0.2614693515469319 0.7131714763054765 0.4757396543710224 1.0 1.0 68 Q96EB6,Q96BN8,P10589,Q8TAT6,Q9NUD5,O95071,O43318,Q05086,Q14258,Q9UER7,P61960,O75179,Q16512,Q96EK7,P40763,Q13309 16 +Positive regulation of leukocyte proliferation 0.3855512080048763 0.7121359629992263 0.4763805864524697 1.0 1.0 16 P09429,P28482,P00813,Q9HCL2 4 +Inner ear receptor cell stereocilium organization 0.4766637029866468 0.7118076316336034 0.4765839062475099 1.0 1.0 5 Q9BW83 1 +Negative regulation of nuclear division 0.3838668287723812 0.7099753523601661 0.4777194208221655 1.0 1.0 23 Q9H900,O60566,Q15645,P33981,P53350,O43684,P50748,O43264,Q969U7,Q96DY7,P14635,Q9Y6G9 12 +Lung morphogenesis 0.3962879736083005 0.7075317383506157 0.4792360964070858 1.0 1.0 9 P60953,O60568,O00203,P28482,O95487 5 +Regulation of cyclase activity 0.431086048178718 0.7069925833388485 0.4795710868089249 1.0 1.0 7 Q99996 1 +Establishment of mitochondrion localization 0.3961215605707943 0.706698993478833 0.4797535551931102 1.0 1.0 9 Q9NZ32,P27695 2 +Folic acid containing compound catabolic process 0.6166002296069608 0.7054285693841659 0.4805435699606899 1.0 1.0 3 Q9NRN7 1 +Regulation of phospholipid catabolic process 0.837014925373136 0.704751003644252 0.4809652047095993 1.0 1.0 2 Q8WTV0 1 +Cellular response to mechanical stimulus 0.3817294764122256 0.7036453131833963 0.481653684778238 1.0 1.0 13 P45985,Q14790,Q99439,P48506,Q9UKL3,P49327 6 +Positive regulation of posttranscriptional gene silencing 0.3839375437260565 0.7033879071521297 0.4818140406528981 1.0 1.0 16 P26196,P36507,P51114,Q04637,Q9HAV4,Q06787,P40763 7 +Amyloid beta metabolic process 0.3829372765880932 0.7010610290392657 0.4832649295986775 1.0 1.0 15 Q13526,Q13464,P42574,P14735,O75116,P27695 6 +Apoptotic cell clearance 0.4296825046245767 0.7005147192524835 0.4836059161401422 1.0 1.0 7 Q8WTV0 1 +Monosaccharide metabolic process 0.2661792176873873 0.7003242866142712 0.4837248078922989 1.0 1.0 73 Q96EB6,P11310,P34949,P11413,P51570,P04075,P09972,P08237,O15357,Q96C23,P31751,P17858,Q9UKK9,O00330,P85037,Q9UNI6,Q00796,P78417 18 +Auditory receptor cell development 0.4736759527625658 0.6990595743275502 0.4845148009427458 1.0 1.0 5 O95487 1 +Response to interleukin 1 0.3824005556100506 0.6981807072200692 0.4850641902333399 1.0 1.0 15 P48506,Q14694,Q92900,O43318,Q9H6S0,Q01804,P78318 7 +Dsrna processing 0.3824045658543302 0.6974476118847394 0.485522713983707 1.0 1.0 22 Q8IWR0,Q5TAX3,P40763,Q08209,O75569 5 +Interleukin 6 mediated signaling pathway 0.6142131979695549 0.6969943153683196 0.4858063513604587 1.0 1.0 3 Q13546,P40763 2 +Regulation of biological process involved in symbiotic interaction 0.4111722470596776 0.6947526920141043 0.487210300230926 1.0 1.0 8 P19474,Q14258,O60493 3 +Regulation of leukocyte apoptotic process 0.3809535856121519 0.6945158009459877 0.4873587951414704 1.0 1.0 14 Q96EB6,P42771,P00813,Q9HCL2 4 +Photoreceptor cell maintenance 0.6133174081815596 0.6938363003783174 0.4877848748814253 1.0 1.0 3 P11166,Q15555 2 +Regulation of glucose import 0.3934988993935107 0.6936088677816137 0.4879275310116573 1.0 1.0 9 P31751 1 +Positive regulation of proteolysis 0.285022734442483 0.6930394022521367 0.4882848245626541 1.0 1.0 90 P62191,P43686,Q9P0J0,O60826,O14737,O75116,Q06787,O00487,Q14997,P46379,P48506,P45974,P61289,P09429,Q9Y5A7,P40763,Q96EB6,O43847,P35579,Q9ULT8,Q14790,Q8IXJ6,O14965,P20248,O95376,P49327,Q16186,O75150,Q15020,Q92688,P62195 31 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.3930607635063748 0.6914283700944216 0.4892963806034889 1.0 1.0 9 Q96EB6,P62081 2 +Negative regulation of axon extension 0.6125274756766041 0.6910547473507129 0.4895311368623931 1.0 1.0 3 Q9P265 1 +Meiotic sister chromatid cohesion centromeric 0.6124216183935514 0.6906822313317664 0.4897652580905678 1.0 1.0 3 O60566,O43683 2 +Bone mineralization 0.3767422480150207 0.6902592278905022 0.4900311830186301 1.0 1.0 11 Q6W2J9,P18074 2 +Macroautophagy 0.2980285212623312 0.6900974165233137 0.4901329277299002 1.0 1.0 102 Q00535,Q8NCE2,Q7Z6Z7,Q9Y5K8,Q9NT62,Q9Y4P1,P27544,Q9Y487,O43318,Q15382,P61960,Q96EB6,Q9Y263,Q6PKG0,P50851,Q9H269,O95352,Q9UHD2,P42858,Q9Y5X3,Q13501,P42574,Q15042 23 +Entry of bacterium into host cell 0.4993278363256916 0.6897522715896256 0.4903499879714827 1.0 1.0 4 P22681 1 +Erbb signaling pathway 0.3814714584968701 0.689211219987875 0.4906903571196481 1.0 1.0 21 P62993,P27695,P19174,Q93034,Q9Y5X3,Q92600,P51452,Q06124,P28482,O00443,P22681 11 +Regulation of nitric oxide synthase activity 0.4441311461459226 0.688669512338069 0.4910312661577556 1.0 1.0 6 Q9Y314,Q8WTV0 2 +Membrane to membrane docking 0.6118244252015537 0.6885817270541499 0.4910865234270458 1.0 1.0 3 P15311,Q13464 2 +Signal transduction in absence of ligand 0.3803175251152974 0.6870335783228327 0.492061568833253 1.0 1.0 15 P21359,Q99504,P49327 3 +Positive regulation of erythrocyte differentiation 0.3772055320389705 0.6857624283370933 0.4928629324299849 1.0 1.0 12 Q15648,Q99873,P40763,Q16539 4 +G0 to g1 transition 0.8304477611940333 0.6842718677396775 0.4938035079278742 1.0 1.0 2 P23921 1 +Regulation of g0 to g1 transition 0.8304477611940333 0.6842718677396775 0.4938035079278742 1.0 1.0 2 P23921 1 +Positive regulation of g0 to g1 transition 0.8304477611940333 0.6842718677396775 0.4938035079278742 1.0 1.0 2 P23921 1 +Regulation of t cell differentiation 0.3768387104286235 0.6838418504158443 0.4940750364657931 1.0 1.0 12 P09429,P00491,P00813,O00203 4 +Exonucleolytic catabolism of deadenylated mrna 0.3914008883393891 0.68318431898459 0.49449038006866 1.0 1.0 9 Q9Y2L1,Q969T7,Q96C86 3 +Transport of virus 0.4254284810751898 0.680972947687988 0.4958886080770834 1.0 1.0 7 Q06787 1 +Negative regulation of protein localization 0.3301161119900872 0.6776878312125846 0.4979696436142709 1.0 1.0 42 P21359,Q9ULT8,P41240,P17858,O60493,P61960,Q06124,O75116,P78559,P31689,Q08209,P20290 12 +Regulation of myeloid leukocyte differentiation 0.3724470359232474 0.6758166409162479 0.4991570679341295 1.0 1.0 10 P21359,Q14790 2 +Carbohydrate biosynthetic process 0.315613744706452 0.6713603829837448 0.5019909763906907 1.0 1.0 45 Q96EB6,P11310,Q9NR45,P31751,Q00796 5 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.3727867895941625 0.6697048284870546 0.5030459730420485 1.0 1.0 11 Q96EB6,Q96RU2,P46379 3 +Folic acid containing compound biosynthetic process 0.439760046414288 0.6693957841608066 0.5032430401964745 1.0 1.0 6 P00374,P31939 2 +Negative regulation of leukocyte cell cell adhesion 0.3767451321266076 0.6680363639202573 0.5041103806720415 1.0 1.0 15 P42574,Q92990,P09429 3 +Positive regulation of transporter activity 0.3769882094062066 0.6669260756376696 0.5048193540691548 1.0 1.0 22 Q03164,Q99996,P42858,P78417,P28161,P35754,P27695 7 +Free ubiquitin chain polymerization 0.8241791044776146 0.6648980251312023 0.506115718963448 1.0 1.0 2 Q16763 1 +Apoptotic process involved in morphogenesis 0.4929280947466487 0.6638303469760192 0.5067989003217515 1.0 1.0 4 P20248 1 +Rna destabilization 0.3145766130333254 0.6632517929328414 0.5071693054047055 1.0 1.0 45 Q9Y2L1,P67809,Q6Y7W6,Q96C86,Q9C0B1,Q5PRF9,Q92900,Q5TAX3,Q9UIV1,O75534,Q9HCE1,Q6L8Q7,O75116,Q969T7,Q86TB9,Q86W50,A5YKK6 17 +Synaptic vesicle budding 0.6042647395033818 0.6621491249189533 0.5078756552589958 1.0 1.0 3 O00203 1 +Endosome to lysosome transport 0.3762335476724799 0.6620483390104626 0.5079402426903532 1.0 1.0 16 P20645 1 +Selective autophagy 0.3692373156601769 0.661077842208526 0.508562394339032 1.0 1.0 28 Q9UHD2,P42858,P50851,P61960,Q9Y4P1,Q13501,P27544 7 +Regulation of cytoplasmic translation 0.3747012861150668 0.6572383785988067 0.5110276518392971 1.0 1.0 15 P14618,P67809,Q06787 3 +Triglyceride biosynthetic process 0.4365999032278223 0.6555502534736476 0.5121135422988141 1.0 1.0 6 Q8WTV0 1 +Dephosphorylation 0.2901401620674521 0.6550274401856969 0.5124500871080175 1.0 1.0 98 Q08623,P31946,P63151,Q8NCE2,Q69YH5,Q99956,Q9NPH0,Q96P16,Q9UNI6,O75116,Q96DE0,O00743,Q8TF05,Q96PE3,Q99504,O60942,P08238,P67870,P51452,O15355,Q969T7,Q5TFE4,Q08209,Q9UPR3,Q8IV63,Q70Z53,Q13555,Q13526,Q5H9R7,Q15257,O15357,P30307,Q06124,Q9ULE6,Q9H0R4,Q9H993,Q9H2U2,P30154,O95861,P42858,Q14738,Q01968,P60510,Q13614,P78318 45 +Protein poly adp ribosylation 0.6001791579575952 0.6479895243171794 0.5169917258043286 1.0 1.0 3 Q9UGN5,P09874 2 +Negative regulation of gluconeogenesis 0.6000849750278758 0.6476641867915528 0.517202172419478 1.0 1.0 3 Q13043 1 +Negative regulation of cilium assembly 0.5998735983076051 0.6469342039347933 0.5176745277684265 1.0 1.0 3 P50570 1 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3475769114348914 0.6450195992888683 0.5189144846793392 1.0 1.0 36 Q00653,P00813,P36915,P00492,O43318,P09429,Q96FZ2,Q16512,Q9UQ84,P40763 10 +Leukocyte proliferation 0.3255964980081247 0.6445197945829316 0.5192384259040836 1.0 1.0 42 P00813,P42574,P00492,Q92990,Q9UHD2,Q96IZ0,P17812,P09429,P62753,P28482,Q16512 11 +Protein modification by small protein conjugation 0.38231186138228 0.6443694666529064 0.5193358792065146 1.0 1.0 195 Q00535,Q15369,Q7Z6Z7,Q96DY7,Q14999,O60566,P49427,Q86VP6,Q13617,Q9C0C9,Q9UPT9,Q9Y263,Q5TAQ9,Q9Y4B6,P61086,P55786,Q05086,O60678,O95376,O95352,Q96BN8,O94822,Q93008,Q2VPK5,P52888,Q14527,Q9Y3I1,Q9UER7,P22314,P22681,Q9Y314,P61081,P48506,P45974,P61960,Q96BK5,Q15386,Q8N806,Q9UL15,Q9UJX4,P15880,O95628,Q6W2J9,A0AVT1,Q96JP5,P62841,Q16763,Q5T4S7,Q92990,Q93034,Q9NT62,Q14258,Q9H1B7,Q9UPN9,Q13619,Q9NR09,Q9UBT2,P68036,O43684,Q04323,P19474,P61962,P31689,P49407,Q96EB6,Q8TBC4,Q13618,Q13564,Q7Z7E8,O75150,P07900,Q5VTR2,Q13501,P60866,Q13309,P62081,Q96FW1,Q8IWV7,Q9Y5A7,Q9UII4,Q9ULT8,O95071 82 +Regulation of t cell proliferation 0.3735983013999828 0.6440804270992916 0.5195232818164324 1.0 1.0 20 Q9HCL2,Q92990,Q96IZ0,P09429,P42574 5 +Rna interference 0.3675989088016883 0.6430214607449326 0.5202101746479837 1.0 1.0 11 Q9HAV4 1 +Maintenance of centrosome location 0.8167164179104514 0.642066737571138 0.5208298517836414 1.0 1.0 2 Q99996 1 +Maintenance of organelle location 0.8167164179104514 0.642066737571138 0.5208298517836414 1.0 1.0 2 Q99996 1 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.262883642063739 0.6416072157956209 0.5211282466368219 1.0 1.0 75 P62993,Q9UQB8,Q93034,Q16539,Q16512,P22681,P19174,P11802,P16949,P51452,Q96TA1,P40763,Q96EB6,Q6Y7W6,Q8IXJ6,P31751,Q14155,Q06124,P14735,P28482,P43490,Q96B36,Q13153,Q9Y5X3,P46109,O14654,P42574,P27695 28 +Regulation of receptor mediated endocytosis 0.3699603060272728 0.6413096231635739 0.5213215381998002 1.0 1.0 25 P41440,O00401,P50570,Q9Y5K6,Q13432,P49407,Q9H3U1,Q06787,Q9UL63,Q13614,P22681 11 +Programmed necrotic cell death 0.3726387637358395 0.6405546903352063 0.5218120456141668 1.0 1.0 17 Q13572,Q9NX46,Q14790,O00429,P55212,P06737,P49327 7 +Regulation of phosphoprotein phosphatase activity 0.3729244116203666 0.6399981654768604 0.5221737920549139 1.0 1.0 19 O75116,P67870,Q15257 3 +Cytokine mediated signaling pathway 0.2675678476721715 0.6381029804973489 0.5234066465269711 1.0 1.0 53 Q96EB6,Q14790,Q96BN8,P43034,Q9UHD2,Q9Y3Z3,P61086,Q01804,O15111,O43318,P63241,P67870,P49327,Q15648,P40763,Q06124,P22681 17 +Adherens junction maintenance 0.5965959988056254 0.6356471340831762 0.5250064408167148 1.0 1.0 3 Q96AC1,Q07157 2 +Cell cell junction maintenance 0.5965959988056254 0.6356471340831762 0.5250064408167148 1.0 1.0 3 Q96AC1,Q07157 2 +Negative regulation of dephosphorylation 0.3695777784437152 0.6347677991718524 0.5255798675670198 1.0 1.0 14 O75116,Q15257 2 +Centromeric sister chromatid cohesion 0.4582360479834365 0.6341517449499283 0.5259817959894018 1.0 1.0 5 Q9GZZ1,O60566,O43683 3 +Regulation of neuronal synaptic plasticity 0.381149976159861 0.6328933152482759 0.5268033134271415 1.0 1.0 9 P21359,Q15042 2 +Positive regulation of type i interferon mediated signaling pathway 0.4851107806056066 0.6325439586016846 0.5270314935929812 1.0 1.0 4 Q9UHD2 1 +Regulation of gliogenesis 0.3680992066939833 0.6323982650301103 0.5271266673635346 1.0 1.0 13 Q8IXJ6,P21359,Q15382,O14744 4 +Head morphogenesis 0.4574915769372563 0.6310663649365983 0.5279971323947286 1.0 1.0 5 Q15042 1 +Negative regulation of histone methylation 0.3634350871010368 0.6297793634245419 0.5288389492629331 1.0 1.0 10 Q6W2J9,P26358 2 +Amyloid beta formation 0.3670403589693108 0.6269602972666136 0.5306852606530594 1.0 1.0 13 Q13526,Q13464,P42574,O75116,P27695 5 +Minus end directed organelle transport along microtubule 0.8116417910447766 0.6266922657398772 0.530860974651183 1.0 1.0 2 Q8TD16 1 +Response to reactive oxygen species 0.3441383068048136 0.6225686528796287 0.5335680160313241 1.0 1.0 36 Q96EB6,Q9NX46,P17655,Q9H8V3,Q96IZ0,P00374,Q05086,P42574,P28482,P27695 10 +Golgi ribbon formation 0.4553002118618227 0.62200982948817 0.5339354046433584 1.0 1.0 5 Q92614 1 +Cell adhesion mediated by integrin 0.4550518786222683 0.620985925504663 0.5346088836668039 1.0 1.0 5 P00813,Q06124 2 +Regulation of microvillus organization 0.4818463040949806 0.6196096610603238 0.5355148046670453 1.0 1.0 4 Q6IBS0,P15311 2 +Thymus development 0.3779443498788359 0.6174015689075286 0.5369698874397268 1.0 1.0 9 P28482,O95067 2 +Positive regulation of muscle cell differentiation 0.3639010688254862 0.6171348643116515 0.537145774182922 1.0 1.0 12 Q96EB6,Q9UGN5,Q16539,Q86TU7,Q96TA1,Q14012 6 +Monovalent inorganic anion homeostasis 0.4810987263765567 0.616658953828363 0.5374597002551824 1.0 1.0 4 Q9Y666 1 +Positive regulation of carbohydrate metabolic process 0.4111650687125224 0.6165538445933395 0.5375290461579305 1.0 1.0 7 P31751 1 +Negative regulation of developmental growth 0.3605326820243933 0.6151652451703475 0.538445597437065 1.0 1.0 10 P11413,Q8N0X7,Q9P265 3 +Protein localization to chromosome centromeric region 0.3645489245235661 0.6142243282590241 0.5390670991216178 1.0 1.0 13 Q9H900,Q9P258,O43684,P50748,O43264,Q96DY7 6 +Pyrimidine containing compound metabolic process 0.3649515156739861 0.6129986248162624 0.5398772490144399 1.0 1.0 25 P11172,Q9BPU6,Q9BZX2,P15531,P33316,P17812,P27708,P04183,P28482 9 +Regulation of inflammatory response to antigenic stimulus 0.3937346748584611 0.6127689870204444 0.5400290998407404 1.0 1.0 8 P19174,P28070,P25786 3 +Nuclear transcribed mrna catabolic process exonucleolytic 0.365210033145283 0.6122708831329395 0.5403585506224666 1.0 1.0 14 Q9Y2L1,Q96C86,Q9UIV1,Q15477,Q969T7 5 +Adherens junction assembly 0.4527435383922389 0.611492330615386 0.5408736941366015 1.0 1.0 5 Q13177,Q9H7S9,Q9BTW9 3 +Cytoskeleton dependent cytokinesis 0.3030217739730281 0.6108868612487115 0.5412744835944403 1.0 1.0 46 Q9H8V3,Q13432,P16949,Q96Q89,O75116,Q14999,P40818 7 +Response to muramyl dipeptide 0.4262673505159191 0.6108393248894944 0.5413059564883158 1.0 1.0 6 Q92974,Q16539 2 +Regulation of receptor internalization 0.3638532094734427 0.610683067953289 0.5414094175893389 1.0 1.0 13 P41440,Q15334,Q06787,Q9UL63,Q13614,P49407 6 +Peptidyl lysine trimethylation 0.3670667255487896 0.6087153051872357 0.5427131604386375 1.0 1.0 19 Q03164 1 +Negative regulation of epithelial cell migration 0.3761312634602094 0.6086924599773628 0.5427283057333063 1.0 1.0 9 P09429,P67870 2 +Meiotic cell cycle process 0.3074699366161767 0.6085864147050561 0.5427986114957568 1.0 1.0 45 P33981,P53350,P42695,O95067,O60566,P46379,O60921,P35579,Q15645,O14965,Q8IXJ6,Q08J23,P30307,P52701,Q9NTJ3,Q6IBW4,O95347,Q9Y620,Q15021,Q15003 20 +Negative regulation of protein localization to nucleus 0.3760454285309067 0.6082811233516127 0.5430010385097988 1.0 1.0 9 P61960 1 +Negative regulation of chemotaxis 0.4518145513202968 0.6076840037438167 0.5433970743372778 1.0 1.0 5 P30046,P51452 2 +Mitotic chromosome condensation 0.3619045894864396 0.6070323778057348 0.5438294251533493 1.0 1.0 12 Q6IBW4,P42695,O95347,Q15021,Q15003,Q9NTJ3,Q9BPX3 7 +Oxidative rna demethylation 0.8050746268656763 0.6069848817139951 0.5438609452817147 1.0 1.0 2 Q6P6C2 1 +Oxidative demethylation 0.8050746268656763 0.6069848817139951 0.5438609452817147 1.0 1.0 2 Q6P6C2 1 +Fat cell proliferation 0.8050746268656731 0.6069848817139857 0.5438609452817209 1.0 1.0 2 Q13501 1 +Small gtpase mediated signal transduction 0.2873049164068876 0.6060699673120361 0.5444682929415672 1.0 1.0 100 P41440,P42771,O75116,Q9Y6D5,P22681,Q15392,Q96N67,P26358,Q15382,P16949,Q96RU2,P40818,P21359,Q96T51,Q86X10,Q14185,P20248,Q92538,Q9H8V3,Q13501,O95630 21 +Methylation 0.3010973310945897 0.6055440120932915 0.5448175903244492 1.0 1.0 113 Q03164,Q8NCA5,Q9BV86,Q9BV44,Q7L2J0,Q7Z2T5,Q14353,O60725,Q9UJA5,P26358,Q86TU7,Q96TA1,Q99873,Q96EB6,Q99707,O60294,Q08J23,Q7Z4G4,Q8TEA1,P57081,Q8N1G2,Q9UBP6,Q9H993,Q6W2J9,P18615,O14744,Q5VTR2,Q86W50 28 +Positive regulation of neurotransmitter transport 0.5874390209853122 0.604443842115766 0.5455485949309242 1.0 1.0 3 Q15042 1 +Phosphatidylcholine metabolic process 0.3597123556777248 0.60310472545853 0.5464390230427068 1.0 1.0 11 P17655,P35790 2 +Flavin containing compound metabolic process 0.5866836871250705 0.6018925265358911 0.5472456792723515 1.0 1.0 3 Q969G6 1 +Regulation of ossification 0.3616302800528955 0.5994135562968109 0.5488971391868385 1.0 1.0 13 Q6W2J9,P20248,Q06124 3 +Regulation of ribosome biogenesis 0.5858465213496494 0.5990689418993581 0.5491269116917341 1.0 1.0 3 Q96BK5,Q96DE0 2 +Regulation of bone mineralization 0.4070993964210104 0.598533554221866 0.549483976852279 1.0 1.0 7 Q6W2J9 1 +Establishment of epithelial cell apical basal polarity 0.4069598760878945 0.5979180537811988 0.5498946128790503 1.0 1.0 7 P15311,Q9P1Y5,P60953,P26038,O14745 5 +Positive regulation of protein catabolic process 0.2468670237844528 0.5971559632687078 0.5504032570640478 1.0 1.0 65 O75925,P62191,P43686,P62333,P53350,Q9P0J0,Q7Z6Z7,O60826,Q06787,Q96QK1,P46379,P48506,P45974,O75832,O43765,P35241,Q9Y5A7,O43847,Q9ULT8,O14965,Q8IXJ6,O95376,P14735,O95352,Q9Y4X5,O75150,P07900,Q9BW61,P15311,P62195 30 +Cdp choline pathway 0.8014925373134363 0.5963282568058238 0.5509559577689038 1.0 1.0 2 P35790 1 +Intra golgi vesicle mediated transport 0.3640800735759276 0.5956975996088135 0.5513772620695181 1.0 1.0 17 P53618,O14579,P53621,Q9Y678,P54920,P61923,Q14746,Q96JB2,P83436,Q9UBF2,P35606 11 +Cellular response to oxygen levels 0.322351609496044 0.5927271362438085 0.5533637777628202 1.0 1.0 41 Q96EB6,Q9Y487,P55786,P20248,P49327,O75116,O95352,P22681 8 +Regulation of cell projection organization 0.3069483683990425 0.5924298965409941 0.5535627515094212 1.0 1.0 120 P47756,Q9Y3I1,Q8NCA5,P15311,Q00535,Q9UQB8,P60953,Q9H6U6,Q9NT62,P50395,Q15555,Q6IBS0,Q16512,Q86X55,Q06787,Q7L576,Q14999,Q9NZQ3,O00401,Q96QK1,Q9UHD8,P51114,Q9Y3P9,P35241,Q08209,P51116,P78344,Q13555,Q8N0X7,Q9P258,P61160,P10589,Q9UL15,Q15334,Q05086,Q14155,O60493,Q9P265,Q96HC4,Q9HCE1,Q14012,P50570,Q9H4M9,P43034,Q13153,Q9NVG8,P42858,P46109,Q32P28,P35080,P07737,Q8TC07,P27695 53 +Neuron migration 0.3612574192093996 0.5923983802899391 0.5535838507006834 1.0 1.0 25 Q9UIS9,Q9Y263,Q00535,P43034,Q9BSJ2,Q93008,P46109,Q96Q89,Q92974,P40763 10 +Regulation of cytoplasmic translational elongation 0.5837563451776796 0.5920383953555213 0.5538248778346309 1.0 1.0 3 Q9BQC3,Q9H2P9 2 +Positive regulation of clathrin dependent endocytosis 0.7991044776119411 0.5892612292144864 0.5556860488574646 1.0 1.0 2 P50570 1 +Cellular response to arsenic containing substance 0.3718369271737272 0.5882234305223708 0.5563823323952346 1.0 1.0 9 Q9UER7 1 +Progesterone receptor signaling pathway 0.4737788114335818 0.5879982877695683 0.5565334421027082 1.0 1.0 4 Q05086 1 +Positive regulation of protein serine threonine kinase activity 0.3467688944696947 0.5875569569706686 0.5568297094006738 1.0 1.0 33 P14174,P41240,P52564,P46940,Q02750,Q16512,Q9Y376,P36507,O43318,P08238,O75832,Q96AC1,Q96EB6,Q13043,Q14012,Q12802,Q99741,Q13153,Q9Y4R8,O75909,P14635 21 +Regulation of ligase activity 0.4730400976502826 0.5851299069457899 0.5584603708253888 1.0 1.0 4 P48507 1 +Positive regulation of cell matrix adhesion 0.3559868294350435 0.584540710992253 0.5588565835638617 1.0 1.0 11 Q96AC1,Q00534,Q13464,Q13630 4 +Postreplication repair 0.355961953412818 0.5844174177136948 0.5589395110574162 1.0 1.0 11 P49005 1 +Peptidyl proline modification 0.3350855182326885 0.5840192131334035 0.5592073856725404 1.0 1.0 37 Q9BV86,O00170,Q15257,Q9GZT9,Q8WUA2,P13674,Q9Y237 7 +Positive regulation of cell cycle g1 s phase transition 0.3621036440738905 0.5834535022030357 0.5595880499384993 1.0 1.0 21 Q13619,P35241,O75179,Q7L2J0,Q96DY7,P31350,P23921,P27695 8 +Actin filament bundle organization 0.3040765293451105 0.5830728181946839 0.5598442811848878 1.0 1.0 45 Q96AC1,Q9UQB8,Q13153,P35611,Q7Z460,Q13618,Q9Y613,Q96IZ0,P35241,P16949,P35080,O75116,P07737,Q16512,P49407 15 +Monocyte differentiation 0.4028257462065377 0.579770220704779 0.5620695820614421 1.0 1.0 7 Q00534,O00625,P49327,Q15648 4 +Labyrinthine layer development 0.3698994997085998 0.5790641586227766 0.5625458828970569 1.0 1.0 9 P20248,Q14790,Q9NR09 3 +Organic hydroxy compound catabolic process 0.3570108977736567 0.5762233257958769 0.5644642407495772 1.0 1.0 13 Q8WTV0,O95861,Q15036,Q00796,Q01968,Q13614,P16930 7 +Positive regulation of macroautophagy 0.3580183397823008 0.5745413825281895 0.5656015054272476 1.0 1.0 25 Q96EB6,Q6PKG0,P42858,O43318,Q15042,P27544 6 +Axonal transport 0.3598453874030145 0.5732540264436007 0.5664727085541201 1.0 1.0 22 Q9NZ32,P43034,Q03001,Q9Y2T2,P27695,O00203,Q14203,P33176,Q14204,P78559,O14617,O60333 12 +2fe 2s cluster assembly 0.4698327359617523 0.5727288797666056 0.5668282801576265 1.0 1.0 4 O76003,Q9Y697,Q9H3K6 3 +Positive regulation of phosphorus metabolic process 0.3349944546974767 0.5706702687610242 0.5682231760915153 1.0 1.0 151 O00560,Q05639,P41440,Q00535,P33981,Q92990,P17655,P60953,Q69YH5,P52564,P53350,P41240,Q99570,P46940,Q92600,Q9UER7,Q9UNI6,Q6PJG6,Q92796,O75116,O96017,Q16512,Q06787,Q9Y376,Q99996,Q96N67,P36507,P51114,P22059,O43318,P08238,O75832,P67870,Q96AC1,Q92974,Q99627,P51116,P49407,Q8IV63,Q96EB6,Q13526,Q13464,Q15257,Q13043,P31751,P61086,Q15334,Q13432,P20248,Q08AM6,P49327,Q06124,Q04637,P28482,Q92616,Q14012,Q99741,P35080,Q13153,P07900,Q9UHD2,Q9H8V3,Q15058,O75909,Q14738,P46109,Q13501,Q96JP5,P13010,P14635 70 +Negative regulation of blood vessel endothelial cell migration 0.4426734825661201 0.5706059887167494 0.5682667580792613 1.0 1.0 5 P67870 1 +Negative regulation of cellular amide metabolic process 0.271492775080743 0.5699605865911657 0.5687044304833244 1.0 1.0 89 Q9C0B1,Q92900,Q5TAX3,Q92600,Q6L8Q7,O75116,Q06787,P26196,P51114,P07814,Q969T7,Q86TB9,P40763,P51116,Q6Y7W6,Q13526,Q6PKG0,Q13464,Q5PRF9,Q9UIV1,P00374,O75534,Q04637,Q9HCE1,Q9Y2L1,P05198,Q96C86,P06730,O60573,P67809,A5YKK6,Q86W50,P27695 33 +Fc receptor mediated stimulatory signaling pathway 0.442236281486261 0.5688512674887216 0.569457079301958 1.0 1.0 5 Q16512 1 +Embryonic organ development 0.2476874521056226 0.5688213382781534 0.5694773922033995 1.0 1.0 55 Q03164,P00813,Q9ULT8,Q14790,Q9NR09,P27635,P28482,Q07864,P20248,Q15648,O75569 11 +Spindle organization 0.2679584749845644 0.5680037829019932 0.5700323992708913 1.0 1.0 86 Q9BV86,Q9Y295,P33981,Q7Z460,Q9HBM1,Q15555,O95067,Q15813,Q9BT25,O96017,Q14008,Q9UH99,Q96CW5,P16949,P35579,Q15257,Q7Z4H7,O14965,Q9BSJ2,Q14203,P07437,O75351,P14635,Q15398,Q14204,Q15691,P15311,P52732 28 +Muscle tissue development 0.236859877275722 0.5674544516652587 0.5704054640476128 1.0 1.0 59 P11310,P41440,P11413,P21359,Q00535,P61201,Q15648,Q99873,Q08209 9 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.7916417910447773 0.5673749928696763 0.5704594361616462 1.0 1.0 2 P42574 1 +Renal system process 0.3508615915046428 0.5672921156250157 0.5705157328380266 1.0 1.0 10 Q9Y5X3,Q16512,Q9UNF1 3 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.5762597032195327 0.5670542884989727 0.5706772982314858 1.0 1.0 3 P33316 1 +Dtmp metabolic process 0.5762597032195327 0.5670542884989727 0.5706772982314858 1.0 1.0 3 P33316 1 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.5762597032195327 0.5670542884989727 0.5706772982314858 1.0 1.0 3 P33316 1 +Regulation of membrane protein ectodomain proteolysis 0.5761687548354493 0.5667534668072384 0.570881689541844 1.0 1.0 3 O43847 1 +Phosphatidylinositol phosphate biosynthetic process 0.3523512984959283 0.5666179331747888 0.5709737883612924 1.0 1.0 11 Q96PE3,O95861,Q99570,Q01968,P42356,O00443 6 +Axon development 0.2610011581323714 0.5658068576027123 0.5715250842256667 1.0 1.0 80 P41440,Q00535,Q9UQB8,P78559,Q16512,Q9BPU6,Q96N67,P16949,Q96TA1,Q66K74,Q8N0X7,Q99707,P00374,Q9P265,Q06124,P50570,P43034,Q93008,P42574 19 +Positive regulation of muscle contraction 0.3995677244203646 0.5655946567506391 0.57166936095896 1.0 1.0 7 P00813 1 +Hepatocyte growth factor receptor signaling pathway 0.3987313144606537 0.5619739909341224 0.5741337399101925 1.0 1.0 7 Q8IXJ6,Q16512,P16949 3 +Positive regulation of lipid localization 0.3526310192715344 0.560851777427439 0.5748985861021136 1.0 1.0 12 Q96EB6,Q8WTV0,Q9H4M9 3 +Establishment of mitotic spindle localization 0.3549388939130328 0.5604535863196015 0.5751700895906642 1.0 1.0 14 P43034,P53350,Q7Z460,P42858,Q14203,O43264,P63172 7 +Sensory organ morphogenesis 0.354348793637866 0.5600809935642115 0.5754241939229923 1.0 1.0 26 P21359,Q15555,Q8NHU6,P28482,P40763,O75569 6 +Negative regulation of mitotic cell cycle phase transition 0.2649101941162631 0.5599187658867348 0.5755348480627673 1.0 1.0 52 Q9Y3I1,Q96K76,P33981,P53350,Q92547,O96017,P50748,Q9Y6G9,Q9NXR7,O60566,O43684,O60921,Q96BK5,O43683,Q9H900,Q6Y7W6,Q15645,Q13564,Q7Z7L1,Q99741,O43264,Q969U7,P14635 23 +Protein destabilization 0.349200072521653 0.5592026040132236 0.5760234561811743 1.0 1.0 10 Q96EB6,P53350,Q13618,P42858,P19474 5 +Regulation of skeletal muscle contraction 0.573831434771825 0.5590417907668742 0.5761331994328542 1.0 1.0 3 P78417 1 +Nuclear transcribed mrna catabolic process deadenylation independent decay 0.7886567164179135 0.5587068144366529 0.576361827900584 1.0 1.0 2 Q96F86 1 +Regulation of anatomical structure size 0.2757262859476344 0.5580576519589225 0.5768050168991352 1.0 1.0 94 P47756,P62993,Q9P2J5,Q00535,Q9UQB8,Q6IBS0,O75116,Q96ER9,P47755,O15020,P35611,P48506,P08238,P35241,O00443,P60981,P78344,Q8N0X7,Q13464,Q9Y666,Q9UEY8,Q9P265,Q96B36,P50570,P43034,O60568,P35080,P07737,P15311,Q9BPX3,P48507 31 +Regulation of type i interferon mediated signaling pathway 0.3530336657789932 0.5565153412449104 0.5778586098857943 1.0 1.0 13 Q14166,Q9UHD2,Q9Y3Z3,P61086,Q9UIV1,Q06124 6 +Chromosome movement towards spindle pole 0.4653372201831103 0.5554962194080575 0.578555295319855 1.0 1.0 4 P61160,Q15398 2 +C terminal protein lipidation 0.7874626865671692 0.5552536777275261 0.5787211582214313 1.0 1.0 2 O95352 1 +Oogenesis 0.356377574287652 0.5542260037726219 0.5794241840999295 1.0 1.0 18 Q15645,O14965,Q8NHU6,Q5TAX3,Q9H6S0 5 +Adp metabolic process 0.3411123972403703 0.5535112398757976 0.579913386192533 1.0 1.0 33 P51570,P04075,P09972,P08237,P14618,P36404,P00568,P17858,P36871,Q9BW91,P85037,Q01813,P18669,P00558,P40763,P00338 16 +Dttp metabolic process 0.5716019417884197 0.5517208526655992 0.5811396208527215 1.0 1.0 3 Q9H773 1 +Monocyte chemotaxis 0.3958979075079086 0.549766411870411 0.5824795990946756 1.0 1.0 7 P09429 1 +Regulation of epithelial to mesenchymal transition 0.3794896890945599 0.548175875032225 0.5835711456065122 1.0 1.0 8 O00560,Q7Z460,Q96AC1 3 +Fatty acid transport 0.3550626556514387 0.54755761588628 0.5839956988186463 1.0 1.0 18 O43772 1 +Regulation of smooth muscle cell differentiation 0.3953269146713493 0.5473172793356674 0.5841607746581094 1.0 1.0 7 Q96EB6,P26358 2 +Regulation of establishment of planar polarity 0.4366789281047268 0.5467029010145148 0.5845828608391181 1.0 1.0 5 O95487 1 +Rap protein signal transduction 0.4365154731131876 0.546055942045043 0.5850274836358405 1.0 1.0 5 Q15058,P22681 2 +Response to isoquinoline alkaloid 0.5697268577780019 0.5455905570887213 0.5853474167825039 1.0 1.0 3 P63151 1 +Regulation of skeletal muscle tissue development 0.4107688601503779 0.5455742120988166 0.5853586547724796 1.0 1.0 6 P41440,Q96TA1 2 +Regulation of ryanodine sensitive calcium release channel activity 0.4361696479390547 0.5446880175938542 0.5859681073353076 1.0 1.0 5 P78417 1 +Smooth muscle cell differentiation 0.3624803130943689 0.5444482375602024 0.58613305915007 1.0 1.0 9 Q96EB6,P26358 2 +Nad metabolic process 0.3525732679556044 0.5440722912814877 0.5863917271233701 1.0 1.0 15 P85037,P17858 2 +Peptidyl tyrosine dephosphorylation 0.3532408090200558 0.5435348731158377 0.5867615869065117 1.0 1.0 16 Q8NCE2,Q99504,Q99956,P30307,O60942,Q06124,Q13614 7 +Positive regulation of hemopoiesis 0.3536408446199952 0.5425300174587729 0.5874534344958502 1.0 1.0 17 P00491,P00813,Q14790,O00203,P09429,O14617 6 +Autophagy of mitochondrion 0.3368409293694844 0.5424636270564056 0.5874991578751674 1.0 1.0 34 O00429,Q9NT62,P42858,P50851,Q13501,Q9Y4P1,P27544,O95352,P19784 9 +Regulation of striated muscle cell differentiation 0.3487036049360988 0.5416875386638785 0.5880337756662852 1.0 1.0 12 P11413,Q96TA1,Q16539,P67809 4 +Transposition rna mediated 0.7826865671641836 0.5415233332268206 0.5881469193707085 1.0 1.0 2 Q5TAX3 1 +Regulation of plasma lipoprotein particle levels 0.3486017230201694 0.5411936796983371 0.5883740933873931 1.0 1.0 12 Q8WTV0,Q9H4M9 2 +Positive regulation of podosome assembly 0.4614372617539831 0.5406925882955568 0.5887194879516193 1.0 1.0 4 Q16658,Q9BPX3 2 +Regulation of podosome assembly 0.4614372617539831 0.5406925882955568 0.5887194879516193 1.0 1.0 4 Q16658,Q9BPX3 2 +Positive regulation of cell cycle 0.2770674944932208 0.5402825448424882 0.5890021942022039 1.0 1.0 97 Q96Q89,O75116,Q7L2J0,O96017,Q96DY7,P31350,Q9H6S0,P23921,Q96DE0,Q9Y6G9,Q13619,P11802,P08243,P39748,P51452,P19474,Q15648,P35241,P78362,Q9UPT9,Q9P258,Q8IXJ6,O14965,Q13618,Q9UJX4,P30307,Q06124,Q04637,Q16513,O94966,P43034,P43487,P06730,Q9H8V3,Q15058,O75909,O75351,O75179,Q14204,Q15398,P14635,P27695 42 +Regulation of actin filament bundle assembly 0.3516680012934971 0.5401222726499834 0.5891127115937767 1.0 1.0 25 Q13464,Q96AC1,Q13153,Q9Y613,Q7Z460,P35241,P16949,P35080,O75116,P07737,Q16512 11 +Homeostasis of number of cells within a tissue 0.4612574265823923 0.5400133237814527 0.5891878439050671 1.0 1.0 4 Q06124 1 +Muscle organ development 0.3106983052113999 0.5393957812933606 0.5896137913657107 1.0 1.0 42 Q96EB6,P21359,P41440,Q00535,Q14331,O94966,Q16539,P51114,Q15648,P85037,P61201,Q9H3U1,Q96TA1,Q08209 14 +Bradykinin catabolic process 0.4610563301415843 0.5392541078701532 0.5897115300588716 1.0 1.0 4 P14735 1 +T cell differentiation in thymus 0.3465945100299521 0.5386485656727169 0.5901293700720256 1.0 1.0 11 P62753,Q00534,P00813 3 +Extracellular vesicle biogenesis 0.377013754429876 0.5371985217888872 0.591130492237514 1.0 1.0 8 O00560,Q92905,Q8WUM4,Q99816,O75351,Q9UN37 6 +Rna 5 end processing 0.3500344328367901 0.5362937993723456 0.5917555153176202 1.0 1.0 14 O75818,O15091,P05455 3 +Sperm dna condensation 0.566789006130709 0.5360359714467636 0.591933690040936 1.0 1.0 3 Q14997 1 +Regulation of gastrulation 0.5664377426097452 0.53489773997521 0.5927205711969517 1.0 1.0 3 O95747,Q7Z460 2 +Purine ribonucleoside catabolic process 0.7800000000000049 0.5338587902352117 0.5934392353649949 1.0 1.0 2 P00813 1 +Purine deoxyribonucleoside monophosphate catabolic process 0.7800000000000049 0.5338587902352117 0.5934392353649949 1.0 1.0 2 P00813 1 +Deoxyribonucleoside catabolic process 0.7800000000000049 0.5338587902352117 0.5934392353649949 1.0 1.0 2 P00813 1 +Purine deoxyribonucleoside metabolic process 0.7800000000000049 0.5338587902352117 0.5934392353649949 1.0 1.0 2 P00813 1 +Ribonucleoside catabolic process 0.7800000000000049 0.5338587902352117 0.5934392353649949 1.0 1.0 2 P00813 1 +Inosine metabolic process 0.7800000000000049 0.5338587902352117 0.5934392353649949 1.0 1.0 2 P00813 1 +Sulfur amino acid metabolic process 0.3495337672448406 0.5338500238828573 0.5934453009389999 1.0 1.0 14 Q13126 1 +Response to ischemia 0.348269995073454 0.5332426033009612 0.5938656536888054 1.0 1.0 13 O75116 1 +Protein targeting to vacuole 0.3468788421623709 0.5328679684447548 0.5941249798318529 1.0 1.0 12 Q9Y2T2,Q7Z3T8,O00203,Q99570,P20645,O14617 6 +Cellular response to insulin stimulus 0.2829698902663513 0.5317956964499174 0.5948675037321274 1.0 1.0 48 Q96EB6,O60343,Q9UQB8,P14618,P31751,P11802,Q9Y5X3,P07741,Q06124,P43490 10 +Negative regulation of erad pathway 0.5652433562257415 0.5310341816995916 0.5953950925643663 1.0 1.0 3 O43765,Q04323 2 +Female gamete generation 0.3448243090671835 0.529769543951671 0.5962717238931254 1.0 1.0 29 Q96EB6,Q6IBW4,Q15645,P33981,O14965,Q8IXJ6,Q8NHU6,O95067,Q5TAX3,Q93008,Q15003,P62753,Q9H6S0 13 +Filopodium assembly 0.3473605384926516 0.5288422281253935 0.5969149012193835 1.0 1.0 13 P47756,O00401,P60953,Q9H6U6,P51114,Q16658,Q06787,P15311,P51116 9 +Negative regulation of nf kappab transcription factor activity 0.3515222654232076 0.5283968717925218 0.5972239082522937 1.0 1.0 19 P42771,P19474,O60826,Q96BN8 4 +Regulation of establishment of protein localization to mitochondrion 0.351278584695372 0.5266706511818029 0.5984223198647043 1.0 1.0 20 P68036,Q7Z6Z7,P55786,O14737,P31689,P19784 6 +Basement membrane assembly 0.7773134328358224 0.5262373931781892 0.5987232761807566 1.0 1.0 2 Q7Z460 1 +Positive regulation of viral life cycle 0.3742942403004475 0.5252327807721363 0.5994213794252521 1.0 1.0 8 Q06787 1 +Aspartate family amino acid metabolic process 0.3504091805677509 0.5238768766994394 0.6003641787273373 1.0 1.0 22 P11586,P30520,Q9NQR4,Q99707,Q13126,P08243,Q9NRN7 7 +Amygdala development 0.7764179104477658 0.5237066293151935 0.6004826040208098 1.0 1.0 2 P21359 1 +Protein localization to cytoskeleton 0.3504144762910706 0.5228367040570872 0.6010878950023408 1.0 1.0 19 P29372,P33981,O14965,O15344,O60610,Q15555,Q96Q89,P78559,Q15691,Q9UIS9 10 +Protein localization to ciliary membrane 0.5623055064615465 0.521575621480037 0.6019658407317647 1.0 1.0 3 Q9UPT5 1 +Synaptic vesicle maturation 0.4562641312264138 0.5212745715889501 0.6021755123493611 1.0 1.0 4 Q15334 1 +Reelin mediated signaling pathway 0.775522388059703 0.5211807570733158 0.6022408578836858 1.0 1.0 2 P43034 1 +Serine family amino acid metabolic process 0.3492891028360608 0.5209176785577785 0.6024241195546238 1.0 1.0 17 Q9Y617,P11586,P22102,P48506,P32929,P00374,P49903,P48507 8 +Response to copper ion 0.3890269820190755 0.5205479644379778 0.6026817065129455 1.0 1.0 7 Q9UER7 1 +Chromosome separation 0.3037152394655051 0.5188861540946375 0.603840133719773 1.0 1.0 43 P33981,P53350,P50748,Q9Y6G9,Q9H1A4,Q9H4L7,O60566,O43684,P19784,O43683,Q9H900,Q15645,Q13618,Q9UJX4,Q6IBW4,Q99741,Q9UJX5,O43264,Q15003,Q969U7,Q15398,P14635 22 +Negative regulation of reproductive process 0.4042318639678949 0.518775891567193 0.6039170317273839 1.0 1.0 6 P35579,P00813,Q15645 3 +Pyridine containing compound biosynthetic process 0.4293489624086958 0.5179530786451632 0.6044910071740823 1.0 1.0 5 Q9Y617,P43490 2 +Negative regulation of ubiquitin protein transferase activity 0.3449060742868512 0.5170369330816468 0.6051303771925272 1.0 1.0 13 P62081,P60866,O60566,Q9UL15,P62841 5 +Pentose phosphate shunt 0.3721444207491445 0.5158433179351706 0.6059638452026839 1.0 1.0 8 P11413,P18669,O95336 3 +Response to hydroxyurea 0.4033654567173011 0.5152592232914602 0.6063718892433747 1.0 1.0 6 Q9BY42,Q06787 2 +Negative regulation of mapk cascade 0.3405097042267116 0.5149698200316621 0.6065741096526758 1.0 1.0 30 P21359,Q8IV63,P43034,P30086,P41240,Q99956,Q96S59,P47897,O75832,Q96KB5,P51452,Q96P70,P31689,P15311,Q14152,P78318 16 +Positive regulation of ligase activity 0.5600817244418685 0.5144589530995389 0.6069311512660218 1.0 1.0 3 P48507 1 +Integrin mediated signaling pathway 0.3478849567213047 0.5140178368169791 0.607239520105701 1.0 1.0 17 P35579,Q9P258,Q03001,P60953,Q13618,Q14185,P22392,Q96AC1,Q9Y490,Q06124 10 +Protein localization to microtubule end 0.7728358208955245 0.5136327346012515 0.6075087886601156 1.0 1.0 2 Q15555 1 +Regulation of hippo signaling 0.4281892628874086 0.5134549727999925 0.607633100029358 1.0 1.0 5 Q16539 1 +Positive regulation of type i interferon production 0.3485791891348441 0.5133390975363776 0.6077141393671035 1.0 1.0 21 P41440,Q9BUI4,O14802,Q9NUD5,Q9UHD2,Q13283,Q06124,Q9NW08,O15111 9 +Positive regulation of protein targeting to membrane 0.3871045851085094 0.5124745934020606 0.6083188971359448 1.0 1.0 7 P31751 1 +Negative regulation of nervous system development 0.3484344062917827 0.5123466259046296 0.6084084386745194 1.0 1.0 20 P21359,Q9UIS9,Q8N0X7,Q00535,Q8IXJ6,Q9P265,P63172,Q08209 8 +Regulation of histone methylation 0.3380758197471224 0.5114739197547002 0.6090192459357757 1.0 1.0 31 Q96EB6,Q03164,Q6W2J9,P18615,P26358 5 +Regulation of mitotic centrosome separation 0.7719402985074644 0.5111266734263011 0.6092623595920319 1.0 1.0 2 P43487 1 +Xenophagy 0.4534720483807423 0.5109013623853761 0.6094201271557584 1.0 1.0 4 Q9UHD2 1 +Organism emergence from protective structure 0.4533569810718628 0.5104755136095739 0.6097183650880043 1.0 1.0 4 Q6W2J9 1 +Negative regulation of histone modification 0.3479695809826965 0.5100207532584935 0.6100369224761741 1.0 1.0 20 Q96EB6,Q01105,Q6W2J9,P26358,Q96FW1 5 +Positive regulation of establishment of protein localization to mitochondrion 0.3455904598144184 0.5099809061034013 0.6100648387339878 1.0 1.0 15 Q7Z6Z7,P68036,P55786,O14737,P19784 5 +Positive regulation of cysteine type endopeptidase activity 0.3395304166785589 0.5095370698711463 0.6103758214006691 1.0 1.0 30 Q96EB6,Q14790,Q9P0J0,P20248,P09429,O14737 6 +Regulation of t cell apoptotic process 0.4271659393197613 0.509497632777641 0.6104034571863242 1.0 1.0 5 P00813 1 +Response to human chorionic gonadotropin 0.7713432835820913 0.5094587499997192 0.6104307050755691 1.0 1.0 2 P48506 1 +Response to bacterium 0.2423924507184588 0.5074515475759955 0.6118380249922193 1.0 1.0 69 Q8WTV0,Q9Y263,Q14790,Q9UQB8,P17655,Q9UHD2,O60493,P09429,P06737,O75179,P42574,P28482 12 +Metaphase anaphase transition of cell cycle 0.3309116438193601 0.5074297155342792 0.6118533400933595 1.0 1.0 34 Q99741,Q9H1A4,Q9H900,O60566,Q969U7,Q15645,P33981,P53350,Q9UJX5,Q13618,O43684,Q9UJX4,O43264,Q15398,O43683,P50748,P14635,Q9Y6G9 18 +Positive regulation of attachment of spindle microtubules to kinetochore 0.4523021793957023 0.5065779974539266 0.6124509497245367 1.0 1.0 4 P14635,Q9P258 2 +I kappab phosphorylation 0.4260729671364558 0.5052833013320217 0.6133598696287244 1.0 1.0 5 O43318 1 +Glucose import 0.3394280828060762 0.5045818008349783 0.6138525949196856 1.0 1.0 11 P31751 1 +Regulation of guanyl nucleotide exchange factor activity 0.4511376583580714 0.5022880638109612 0.6154649042111857 1.0 1.0 4 P16949 1 +Regulation of muscle adaptation 0.3438506003537312 0.5016227223267984 0.6159329328294176 1.0 1.0 15 O75116,Q08209 2 +Regulation of cysteine type endopeptidase activity 0.2464581360645941 0.5011332184807921 0.616277369768875 1.0 1.0 54 Q96EB6,Q15392,Q14790,Q96K76,Q9P0J0,P20248,P09429,O14737 8 +Response to follicle stimulating hormone 0.5555640521265831 0.5001177867310328 0.6169921426464453 1.0 1.0 3 P48506 1 +Cellular response to follicle stimulating hormone stimulus 0.5555640521265831 0.5001177867310328 0.6169921426464453 1.0 1.0 3 P48506 1 +Inner ear auditory receptor cell differentiation 0.3839846178172805 0.4994703365616556 0.6174480790866781 1.0 1.0 7 O95487 1 +Embryonic placenta development 0.3427352101008005 0.4962940657457526 0.6196869524965392 1.0 1.0 15 Q9ULT8,Q14790,Q9NR09,P20248,P28482 5 +Stress fiber assembly 0.3409958685186932 0.4942501396341035 0.6211295334108289 1.0 1.0 27 Q13464,Q96AC1,Q13153,Q9Y613,Q7Z460,Q13618,P16949,P35080,O75116,P07737,Q16512,P49407 12 +Toll like receptor signaling pathway 0.3421057445000455 0.4932972030250031 0.621802604385169 1.0 1.0 15 O43318,P41440,Q01804 3 +Response to aldosterone 0.5532994923857892 0.4929890618571815 0.6220203160578235 1.0 1.0 3 P61353,P09874 2 +Vesicle mediated transport to the plasma membrane 0.295756822610331 0.4924545802890593 0.6223980229538111 1.0 1.0 44 Q4J6C6,P50570,Q9H4M9,Q9UID3,P41240,Q96KP1,Q9UJY4,O60826,O60493,Q9Y6D5 10 +Response to arsenic containing substance 0.34075921539368 0.4917365477371961 0.622905597969365 1.0 1.0 14 Q9UER7,Q13535 2 +Regulation of antigen receptor mediated signaling pathway 0.3366561944012602 0.4916422555409538 0.6229722661538475 1.0 1.0 11 P51452,P15311,P00813,Q96IZ0 4 +Negative regulation of secretion 0.3442065331574176 0.4913517738103285 0.6231776672577476 1.0 1.0 20 P21359,P00813,P17858,Q06787,Q08209 5 +Establishment of protein localization to vacuole 0.3392879342162206 0.4904159225513329 0.62383961174478 1.0 1.0 13 P20645 1 +Regulation of endocytosis 0.2910687812138172 0.4892632926193953 0.6246553052617196 1.0 1.0 45 O00560,P41440,Q8N6T3,P60953,P61020,Q9H3U1,Q06787,Q9UL63,P22681,O00401,Q08209,P49407,Q13464,Q96T51,Q15334,Q13432,Q15036,P50570,Q7Z3T8,Q9Y5K6,Q13614 21 +Secondary metabolic process 0.3359739727224168 0.4884786285534843 0.6252108598674841 1.0 1.0 11 P14550,Q9BUT1,P30046,O43488,O75592,Q9Y4G8 6 +Positive regulation of cell projection organization 0.240349266982583 0.4882790473306757 0.6253522005249288 1.0 1.0 69 Q8NCA5,P50570,Q9H4M9,Q9UQB8,P43034,Q9H6U6,Q15555,P42858,Q6IBS0,O60493,Q14155,Q32P28,Q06787,Q14999,P27695 15 +Regulation of cell projection size 0.5517955647494446 0.4882773499421651 0.6253534026510388 1.0 1.0 3 Q6IBS0 1 +Regulation of microvillus length 0.5517955647494446 0.4882773499421651 0.6253534026510388 1.0 1.0 3 Q6IBS0 1 +Positive regulation of cell morphogenesis involved in differentiation 0.341734984609733 0.487980343320283 0.6255637643012839 1.0 1.0 25 Q14999,Q9UQB8 2 +Negative regulation of i kappab kinase nf kappab signaling 0.3340976525764041 0.4876938865745303 0.625766682648865 1.0 1.0 10 O60826,Q14790 2 +Negative regulation of establishment of protein localization 0.3416583167352096 0.4875864455917655 0.6258427982978216 1.0 1.0 25 P21359,P41240,P17858,O60493,P61960,Q06124,P31689,Q08209 8 +Translational elongation 0.3403598178879274 0.4854026349876499 0.6273907636013962 1.0 1.0 26 Q05639,Q9BQC3,Q9Y450,O94822,P63241,Q8N3C0,P13639,P05387,P26641 9 +Response to transforming growth factor beta 0.3333546619566129 0.4852569125516343 0.627494115519073 1.0 1.0 31 O00560,Q9Y3F4,Q96EB6,Q13526,Q13464,Q96AC1,P50570,Q9HCM4,O43318,Q93008,P08238,P46109,Q9H7S9,O14737,O75116,P40763,Q9UPN9 17 +Sensory perception of pain 0.4462154910842266 0.4843092788547785 0.6281663917578428 1.0 1.0 4 Q9BPW8 1 +Bone cell development 0.3955924886080579 0.4840966151226485 0.6283173034121523 1.0 1.0 6 Q15648,Q06124 2 +Histone serine phosphorylation 0.42047488030406 0.4839027252791468 0.6284549061725835 1.0 1.0 5 Q99986,O14965 2 +Regulation of amyloid fibril formation 0.5494925245772782 0.4810974863985728 0.6304472144750402 1.0 1.0 3 Q99471 1 +Negative regulation of amyloid fibril formation 0.5494925245772782 0.4810974863985728 0.6304472144750402 1.0 1.0 3 Q99471 1 +Dendritic spine maintenance 0.5491048368012379 0.4798931010911501 0.6313034070611956 1.0 1.0 3 Q13614 1 +Single strand break repair 0.3942112026606842 0.4786342080465547 0.6321988780720589 1.0 1.0 6 Q96EB6 1 +Amyloid fibril formation 0.394198165339322 0.4785827623525204 0.6322354837137376 1.0 1.0 6 Q93008,Q13546,Q99471 3 +Intraciliary transport 0.3783379850431999 0.4762558958911373 0.6338920821435492 1.0 1.0 7 Q9BW83,Q15154,P36405,Q9UIS9 4 +Positive regulation of dna templated transcription initiation 0.3347530758614818 0.475719551393773 0.6342741900915723 1.0 1.0 12 P53999,Q86VP6,Q9Y2X0 3 +Regulation of mitotic cell cycle 0.3199110335037796 0.4756319596040224 0.6343366023811388 1.0 1.0 147 O00560,Q9Y3I1,Q96K76,P33981,P61254,P53350,P60953,Q69YH5,P42771,P18074,Q92547,Q96Q89,Q7L2J0,Q96DY7,O96017,P50748,P31350,Q14999,P23921,Q9H6S0,Q14166,Q9Y6G9,Q13619,O60566,P35244,Q9NXR7,O43684,P11802,O95905,O60921,P61289,P08243,P51452,Q96BK5,P35241,O43683,Q96EB6,Q9H900,Q9UPT9,Q6Y7W6,Q9P258,Q13526,Q15645,Q8IXJ6,O14965,Q13618,P43246,Q9UJX4,P30307,Q06124,Q04637,Q13564,Q16513,Q7Z7L1,Q99741,Q92538,P43034,O75150,Q9UJX5,P06730,Q15058,O75351,O14744,Q5VTR2,O43264,O75179,Q969U7,Q15398,P14635,P27695 70 +Negative regulation of nucleocytoplasmic transport 0.3627224640430415 0.4754551013678467 0.6344626281382721 1.0 1.0 8 P21359,P61960 2 +Regulation of circadian rhythm 0.3361616034598179 0.4752281805796876 0.6346243430229623 1.0 1.0 28 O75116,Q05086 2 +Positive regulation of erk1 and erk2 cascade 0.3390446089927714 0.4747555595079673 0.6349612119628838 1.0 1.0 16 P30046,P18615,P09429,Q06124 4 +Antigen processing and presentation of exogenous antigen 0.3768761156920472 0.4703155591954104 0.6381295828142814 1.0 1.0 7 O00203,Q03518,O14617,P50570 4 +Visual behavior 0.3613269618190987 0.4695834791287051 0.638652630294029 1.0 1.0 8 P21359,Q9NPQ8 2 +Regulation of cell development 0.264734191399025 0.4684669329862226 0.6394507125606177 1.0 1.0 93 Q00535,Q9UQB8,Q6IBS0,O75116,Q14999,Q96N67,P35611,Q15382,P39019,Q96AC1,Q96TA1,Q08209,P21359,Q8N0X7,Q9P258,O14965,Q14185,Q14155,Q9P265,Q9UIS9,P50570,P43034,Q15058,P46109,O14744,P27695 26 +Regulation of response to cytokine stimulus 0.3368540815900449 0.4673893806322231 0.6402213188846535 1.0 1.0 26 Q14790,Q96BN8,P43034,Q9UHD2,Q9Y3Z3,P61086,Q9UIV1,Q06124,Q15648,Q01804 10 +Neuron projection regeneration 0.3607801420965663 0.4672907750291395 0.6402918555999966 1.0 1.0 8 Q99707 1 +Reproductive system development 0.2380700453974245 0.4672835391957737 0.6402970318224934 1.0 1.0 69 P49770,P00813,Q14999,P22681,O75874,Q15392,Q9NR09,Q15648,Q96EB6,Q9ULT8,Q14790,Q13144,P20248,Q05086,Q06124,P62753,P28482,Q7Z7E8,P42574 19 +Positive regulation of signal transduction by p53 class mediator 0.3342204960421532 0.4669059588720041 0.6405671617927984 1.0 1.0 13 P62081,Q13535,P60866 3 +Positive regulation of cellular response to insulin stimulus 0.3911199412393066 0.4664951482937887 0.6408611195771834 1.0 1.0 6 Q96EB6,Q06124 2 +Regulation of cytoskeleton organization 0.3130964104733896 0.4663717509587166 0.6409494282286383 1.0 1.0 141 P47756,Q9Y696,P62993,Q9Y295,Q00535,Q9UQB8,P53350,P17655,Q7Z460,Q9H6U6,Q15555,Q6IBS0,O75116,P78559,Q16512,P47755,O15020,O00401,Q14008,Q99996,P35611,O15344,P16949,Q9BTW9,P35241,P29372,Q96AC1,Q92974,P60981,Q66K74,Q13464,Q13045,P60983,P04350,Q14203,Q9UEY8,Q14155,P28482,Q15691,Q13153,P43034,P36404,O60610,Q9H8V3,Q9Y5K6,O75351,Q8TD16,P35080,Q14204,P07737,Q9Y613,P15311,Q8NI35,Q9BPX3 54 +Positive regulation of synaptic transmission gabaergic 0.7552238805970175 0.4652936888317291 0.6417211537384013 1.0 1.0 2 P27695 1 +Response to virus 0.2611078664008679 0.4650657885690348 0.641884344631672 1.0 1.0 90 P26641,Q9NUD5,Q9Y3Z3,Q14258,Q9NW08,Q06787,P25787,Q13309,O15111,Q9BUI4,O14802,P13693,Q92499,P16949,P19474,Q9UII4,Q9HCL2,Q9UIV1,P63241,Q9HCE1,Q8TAT6,O75569,O95352,Q7Z7L1,O95801,Q92538,Q9UHD2,P35269,Q00534,O75179,P48643 31 +Regulation of chromosome segregation 0.2785946825016751 0.4641324983307222 0.6425528194119823 1.0 1.0 47 P33981,P53350,Q69YH5,P50748,Q9Y6G9,Q9H1A4,O60566,O43684,P19784,Q99661,O43683,Q9H900,Q9P258,Q15645,Q8IXJ6,Q13618,Q9UJX4,Q7Z5K2,Q99741,Q9UJX5,O43264,Q969U7,Q15398,P14635 24 +Regulation of adherens junction organization 0.7543283582089575 0.4628907315729285 0.6434426913277593 1.0 1.0 2 P35611 1 +Regulation of translational initiation 0.2950364614909106 0.4609787853935193 0.6448138255988363 1.0 1.0 43 P49770,Q7Z478,P78344,P05198,Q6PKG0,O60841,Q14240,Q13144,P46199,Q15056,O43432,Q92499,O75534,Q04637,Q06787,P41567 16 +Ensheathment of neurons 0.3330249889355274 0.4588966264168299 0.6463084014922003 1.0 1.0 28 P49770,P21359,Q13614,Q8IXJ6,P31751,Q13144,Q15058,Q96P11,P18074,Q96PU8,Q8TEW0 11 +Negative regulation of developmental process 0.2762633851254297 0.4584565750551793 0.6466244538787529 1.0 1.0 105 Q00535,Q8N4Q0,Q7Z6Z7,O75116,P11413,P13693,P26196,P26358,P09429,Q96AC1,Q15648,Q99873,Q96TA1,Q08209,P40763,Q96EB6,P21359,Q8N0X7,Q9P258,Q05086,Q9P265,Q06124,P28482,Q6W2J9,Q00534,Q92688,O14744,O75179,P67809 29 +Phagocytosis recognition 0.5420762978992667 0.4582755754188121 0.646754469413199 1.0 1.0 3 Q8WTV0 1 +Cardiac neural crest cell differentiation involved in heart development 0.542004862202367 0.4580580108650616 0.6469107645067917 1.0 1.0 3 P28482 1 +Post golgi vesicle mediated transport 0.3019560218762006 0.4580421283796733 0.6469221748548535 1.0 1.0 41 Q4J6C6,Q92538,P50570,P41240,Q7Z3U7,Q96KP1,Q9UJY4,O60826,Q9Y6D5,P57737 10 +Vitamin b6 metabolic process 0.5419090806301756 0.4577663674283149 0.6471203011867035 1.0 1.0 3 Q9Y617 1 +Adaptation of signaling pathway 0.7522388059701515 0.4573052436237618 0.6474516612859424 1.0 1.0 2 P50570 1 +G protein coupled receptor internalization 0.7522388059701515 0.4573052436237618 0.6474516612859424 1.0 1.0 2 P50570 1 +Positive regulation of rna binding 0.3885922274221479 0.4566589200692152 0.6479162221397035 1.0 1.0 6 Q06787,Q04637 2 +Immunological synapse formation 0.4384707287932956 0.4565441467361893 0.6479987326211374 1.0 1.0 4 P17931,P26038,P31146 3 +Positive regulation of intrinsic apoptotic signaling pathway 0.3341981504231209 0.4563069963133491 0.6481692336156557 1.0 1.0 15 Q96EB6,P62081,O75569,O00429 4 +Response to peptide hormone 0.2535587349100293 0.4561914761350899 0.6482522943585627 1.0 1.0 84 P49770,Q96EB6,O60343,Q9UQB8,P09960,P41240,Q13144,P31751,Q9Y5X3,P20248,P07741,Q06124,O75116,P43490,P40763,P27695 16 +Pteridine containing compound biosynthetic process 0.3424723409049176 0.4551524130668939 0.648999592961371 1.0 1.0 9 P11586,P00374,P31939,P22102 4 +Skeletal muscle adaptation 0.5408678742546734 0.4546011253473124 0.6493962250212761 1.0 1.0 3 Q08209 1 +Regulation of skeletal muscle adaptation 0.5408678742546734 0.4546011253473124 0.6493962250212761 1.0 1.0 3 Q08209 1 +Tissue migration 0.2228899817898788 0.4545360115983698 0.6494430786321916 1.0 1.0 57 Q96EB6,Q8WTV0,P21359,P35080,P19174,Q15555,Q14185,P09429,P67870,Q06124,O75116,Q16512 12 +Receptor signaling pathway via stat 0.3346878512637251 0.4544323026347113 0.6495177068934215 1.0 1.0 16 Q6IA86,Q00535,P22059,O95630,P40763 5 +Negative regulation of transporter activity 0.3300106199492829 0.4541064357220581 0.6497522213814404 1.0 1.0 12 P78417,P28161,Q06787,Q9Y376 4 +Multivesicular body organization 0.3264512268102942 0.4530099914958989 0.6505415468805964 1.0 1.0 10 P53990,Q8WUM4,Q8WUX9,Q9H9H4,Q99816,O75351,Q9UN37,Q92783,Q9NZZ3 9 +Constitutive secretory pathway 0.7504477611940322 0.4525417293269789 0.6508787663555204 1.0 1.0 2 Q7Z392 1 +Macrophage differentiation 0.3723670675694884 0.452180307684248 0.6511390933884718 1.0 1.0 7 Q14790 1 +Positive regulation of receptor internalization 0.4368677997605864 0.4508807259745493 0.6520755155643749 1.0 1.0 4 Q06787 1 +Amino acid activation 0.3133609709649091 0.4508453739645451 0.6521009963624851 1.0 1.0 37 Q9P2J5,Q9BTE6,Q96I59,P26639,O43776,P26640,P49591,P07814,P41250,P47897,P49589,P41252,P23381,P54136,P54577,Q9Y285,Q9NSD9 17 +Positive regulation of calcium ion transport 0.3346239779543127 0.4507547640602046 0.6521663074504649 1.0 1.0 17 P11413,P19174,P42858,P78417,P28161,P27695 6 +Riboflavin metabolic process 0.7495522388059725 0.4501683608188393 0.6525890479457408 1.0 1.0 2 Q969G6 1 +T cell proliferation 0.3324046792228055 0.4498220743469378 0.6528387397018134 1.0 1.0 27 Q9HCL2,P42574,Q92990,Q96IZ0,P17812,P09429,P62753 7 +Response to hydrogen peroxide 0.3299099077294248 0.4496462528139099 0.6529655316704375 1.0 1.0 29 Q96EB6,P17655,Q9H8V3,Q05086,P42574,P27695 6 +Dna replication 0.2894975880778953 0.4494618270262852 0.653098539284648 1.0 1.0 119 P41440,P25205,Q9BTE3,P49005,P23921,P35244,P38935,P49427,P49642,P18858,P78362,Q01105,Q9UBD5,P28340,P20248,Q7Z5K2,Q7Z7L1,Q13535,Q07864,O75179 20 +Peptidyl lysine deacetylation 0.7492537313432872 0.449378486729705 0.6531586478045197 1.0 1.0 2 Q96EB6 1 +Negative regulation of muscle organ development 0.7492537313432859 0.4493784867297022 0.6531586478045217 1.0 1.0 2 O94966 1 +Negative regulation of muscle tissue development 0.7492537313432859 0.4493784867297022 0.6531586478045217 1.0 1.0 2 O94966 1 +Positive regulation of cell maturation 0.7492537313432859 0.4493784867297022 0.6531586478045217 1.0 1.0 2 O14965 1 +Regulation of oocyte maturation 0.7492537313432859 0.4493784867297022 0.6531586478045217 1.0 1.0 2 O14965 1 +Amyloid precursor protein metabolic process 0.3353751230450065 0.4484397068943594 0.6538358906480801 1.0 1.0 21 Q15392,P42574,Q96IZ0,Q96P70,O75116,P27695 6 +Protein k48 linked deubiquitination 0.3301094699748402 0.4482010499703238 0.6540081050323723 1.0 1.0 13 P40818,O94966,Q04323,Q93008,P45974,Q96FW1,Q01804 7 +Regulation of membrane tubulation 0.5387196715899274 0.4481004047719385 0.6540807359398948 1.0 1.0 3 P50570 1 +Response to redox state 0.5386901204085022 0.448011260800035 0.6541450696886151 1.0 1.0 3 Q8IXJ6 1 +Platelet derived growth factor receptor signaling pathway 0.3712150720903479 0.4475934124442462 0.6544466582643957 1.0 1.0 7 P22681 1 +Regulation of cell morphogenesis involved in differentiation 0.3307371697416077 0.447147146583067 0.6547688199126993 1.0 1.0 28 P50570,Q9P258,Q9UQB8,Q14185,Q14155,Q96AC1,Q14999 7 +Regulation of calcium ion transmembrane transporter activity 0.3321935574646111 0.4471305094356826 0.6547808315994417 1.0 1.0 15 P42858,P78417,P28161,Q06787,P27695 5 +Protein deubiquitination involved in ubiquitin dependent protein catabolic process 0.7483582089552261 0.4470126232554861 0.6548659456168173 1.0 1.0 2 Q93008 1 +Synapse organization 0.2289703117175402 0.4467939919833548 0.6550238096297045 1.0 1.0 63 O00560,Q00535,Q9UQB8,P60953,Q16539,Q7L576,O15020,O00401,Q96QK1,P63104,Q13526,P61160,Q15334,P07437,Q14203,Q05086,O60678,Q04637,Q14012,P43034,P46109,P35080,P07737,Q13614 24 +Dna methylation dependent heterochromatin assembly 0.3268018563318823 0.4467902742727094 0.6550264941581934 1.0 1.0 11 P26358 1 +Regulation of protein targeting to membrane 0.3558388360410346 0.446783214799547 0.6550315917583713 1.0 1.0 8 P31751 1 +Regulation of glycolytic process 0.3403023044849382 0.4458622421398864 0.6556967579890749 1.0 1.0 9 P18669,P40763 2 +Ovulation cycle process 0.3855458452570908 0.4449146315746069 0.6563814484191779 1.0 1.0 6 Q96EB6,P42574,P52564 3 +Neuron projection maintenance 0.7471641791044819 0.4438669425734604 0.6571387859934914 1.0 1.0 2 P78559 1 +Hepaticobiliary system development 0.3170667374567993 0.4422938978973429 0.6582765460429498 1.0 1.0 35 P11310,P21359,P00813,O14965,O14744,Q15648,Q9HAU5,P19784 8 +Regulation of kidney development 0.5365780830098589 0.4416600588173379 0.6587352164636144 1.0 1.0 3 O95747,P42224 2 +Regulation of filopodium assembly 0.3272191895406675 0.4415922808516214 0.6587842708183167 1.0 1.0 12 P47756,O00401,P60953,Q9H6U6,P51114,Q16658,Q06787,P51116 8 +Positive regulation of interleukin 6 production 0.3542395329500589 0.4402286944273246 0.6597714791968858 1.0 1.0 8 P40763,P09429 2 +Regulation of phosphatase activity 0.3336428793522068 0.4402136384044238 0.6597823827576723 1.0 1.0 21 O75116,P67870,Q15257 3 +Liver regeneration 0.3233496621056574 0.4392602941793957 0.6604729410273744 1.0 1.0 10 O14965,O14744,P19784 3 +Deoxyribonucleoside triphosphate biosynthetic process 0.5356749381455185 0.438956265557907 0.6606932260907306 1.0 1.0 3 P04818 1 +Ventral spinal cord development 0.5356608359756232 0.4389141049426778 0.6607237760421591 1.0 1.0 3 Q6Y7W6 1 +Activation of innate immune response 0.3332447630158484 0.4387823045467302 0.6608192834104689 1.0 1.0 22 Q9NUD5,P55212,O43318,P09429,Q16512 5 +Negative regulation of epithelial cell proliferation 0.3311039196175654 0.438011980518555 0.661377598702469 1.0 1.0 16 P21359,Q00534 2 +Forebrain morphogenesis 0.7447761194029905 0.4376059807027203 0.6616719350039066 1.0 1.0 2 P21359 1 +Lateral ventricle development 0.74477611940299 0.437605980702719 0.6616719350039075 1.0 1.0 2 Q00534 1 +De novo pyrimidine nucleobase biosynthetic process 0.4079289328219627 0.4373042653921752 0.6618907023994163 1.0 1.0 5 P11172,P27708 2 +Pyrimidine nucleoside diphosphate biosynthetic process 0.4079289328219627 0.4373042653921752 0.6618907023994163 1.0 1.0 5 P11172,P27708 2 +Pyrimidine nucleoside diphosphate metabolic process 0.4079289328219627 0.4373042653921752 0.6618907023994163 1.0 1.0 5 P11172,P27708 2 +Viral rna genome replication 0.3295741005531027 0.4352667599098226 0.6633688094361472 1.0 1.0 15 P42356,O75116 2 +Negative regulation of nuclease activity 0.5341282391135501 0.4343428169406619 0.6640395157551335 1.0 1.0 3 P61221 1 +Negative regulation of cell development 0.3309113315702738 0.4337686435026456 0.6644564539325617 1.0 1.0 25 P21359,Q9UIS9,Q8N0X7,Q00535,Q9P258,Q8IXJ6,Q9P265,P63172,Q08209 9 +Muscle adaptation 0.3307391050370278 0.4329152906423926 0.665076311129599 1.0 1.0 17 O75116,Q08209 2 +N acetylneuraminate catabolic process 0.7426865671641816 0.4321611848826274 0.6656242680040765 1.0 1.0 2 P46926 1 +Response to progesterone 0.406376431132602 0.4316719212751271 0.6659798778187931 1.0 1.0 5 Q05086,Q969T9,P06744 3 +Positive regulation of cytoplasmic translation 0.3232626388226624 0.4311440878847054 0.6663636054050954 1.0 1.0 11 P14618,P67809 2 +Regulation of mrna catabolic process 0.2440683867422595 0.4311328052059439 0.6663718087104415 1.0 1.0 78 Q9Y2V2,Q9C0B1,Q16539,Q92900,Q5TAX3,Q13310,Q6L8Q7,O75116,Q06787,P51114,Q969T7,Q86TB9,O00178,P51116,Q6Y7W6,Q6PKG0,Q5PRF9,Q9UIV1,O75534,Q9HCE1,Q7L8L6,Q9Y2L1,Q96C86,Q6P6C2,P67809,A5YKK6,Q86W50,P27695 28 +Viral budding 0.3518091708313179 0.4303480280542384 0.6669424950651421 1.0 1.0 8 Q8WUM4,O75351,Q9H9H4,Q9UN37 4 +Vitamin transmembrane transport 0.3668142532744475 0.4302499089414807 0.6670138603983982 1.0 1.0 7 P41440 1 +Negative regulation of protein secretion 0.3364321452522114 0.4295023339187469 0.6675576957581719 1.0 1.0 9 Q08209,P17858 2 +Peptidyl lysine hydroxylation 0.4056411888662165 0.4290152456145533 0.6679121298870074 1.0 1.0 5 Q9H267,O60568,Q96AY3 3 +Tight junction organization 0.3310947122472981 0.4286739603108841 0.6681605133048028 1.0 1.0 20 Q13464,O43815,Q8TEW0,Q8WUM4,Q13177,P36404,Q9H8V3,Q9BTW9,O75116,P17612,Q8NI35,P55196 12 +Response to estradiol 0.3292283480953532 0.4260680334486776 0.670058272548453 1.0 1.0 17 P20248,P40763,Q14790 3 +Positive regulation of metaphase anaphase transition of cell cycle 0.3353903311760786 0.4251450809953677 0.6707309163147339 1.0 1.0 9 Q9UJX4,Q15398,Q13618 3 +Negative regulation of transport 0.2399843784981355 0.4245757266439092 0.671145990995212 1.0 1.0 75 P21359,P00813,O60343,P41240,P31751,Q9NT62,P17858,Q13432,O60493,P09429,P61960,Q06124,P78417,P28161,Q06787,Q08209,Q13614 17 +Regulation of protein folding 0.429237781982188 0.4243310735861762 0.6713243805050269 1.0 1.0 4 O14737 1 +Cellular response to exogenous dsrna 0.3798671104333263 0.4233547908082672 0.6720364243397237 1.0 1.0 6 Q9NUD5 1 +Regulation of chromosome separation 0.3084549242652099 0.4228754616042314 0.6723861269363685 1.0 1.0 37 P33981,P53350,P50748,Q9Y6G9,Q9H1A4,O60566,O43684,P19784,O43683,Q9H900,Q15645,Q13618,Q9UJX4,Q99741,Q9UJX5,O43264,Q969U7,Q15398,P14635 19 +Histone h3 k36 methylation 0.3644423075250039 0.4210227383191741 0.6737384780062503 1.0 1.0 7 Q86TU7 1 +Negative regulation of potassium ion transport 0.5294117647058871 0.4204090291183067 0.6741866732317805 1.0 1.0 3 O95747,Q9Y376 2 +Negative regulation of potassium ion transmembrane transport 0.5294117647058871 0.4204090291183067 0.6741866732317805 1.0 1.0 3 O95747,Q9Y376 2 +Negative regulation of cell adhesion 0.3077074413919599 0.4186892797732779 0.6754432313737524 1.0 1.0 37 P21359,Q9P258,Q92990,Q9H6U6,Q96IZ0,P42771,P09429,P51452,Q9BTW9,P42574,Q06124 11 +Regulation of gtp binding 0.3635837738856617 0.4177042176012422 0.6761633882786138 1.0 1.0 7 Q14155 1 +Protein lipid complex subunit organization 0.4272065654817711 0.417380261637015 0.6764002900234654 1.0 1.0 4 Q8WTV0 1 +Tumor necrosis factor mediated signaling pathway 0.3276187700499311 0.4160648286499313 0.6773625656330866 1.0 1.0 18 Q9BRA2,Q04206,Q14790,Q96BN8,P61086,P63241,Q13418,P49327,Q13546,O15111 10 +Response to extracellular stimulus 0.259563232893033 0.4158922876747364 0.6774888232390417 1.0 1.0 94 P11310,Q9UMX5,Q9P2J5,Q9H6U6,Q99570,P85037,Q14258,P22681,P11413,P48506,P08243,P39019,Q15648,Q96EB6,Q9BY44,Q6PKG0,P80303,Q9Y4P8,O00330,Q00796,P49327,P28482,Q92616,O95352,P05198,Q96C86,P30566,P48507 28 +Positive regulation of innate immune response 0.3200352109235727 0.4146275268533081 0.678414593870933 1.0 1.0 31 Q9BUI4,Q9NUD5,Q9UHD2,P61086,Q15648,P55212,O43318,P09429,Q9NW08,Q16512 10 +Bile acid biosynthetic process 0.3172619951278266 0.4128379575984992 0.6797253394201765 1.0 1.0 10 Q96EB6,Q9BZF3 2 +Synapse maturation 0.734925373134331 0.412216966164904 0.6801804026918581 1.0 1.0 2 P63104 1 +Negative regulation of metaphase anaphase transition of cell cycle 0.3272136912762931 0.4105041301951938 0.6814361743543045 1.0 1.0 22 Q9H900,O60566,Q15645,P33981,P53350,O43684,O43264,Q969U7,P50748,P14635,Q9Y6G9 11 +Plasma membrane tubulation 0.4004137440488337 0.4103293877953543 0.6815643370576752 1.0 1.0 5 P50570 1 +Pyrimidine ribonucleoside diphosphate metabolic process 0.4250202834133428 0.4099554446138082 0.6818386320404048 1.0 1.0 4 P11172,P27708 2 +Regulation of gene silencing by rna 0.3271241188164414 0.4098995127632869 0.6818796628145074 1.0 1.0 21 P26196,P36507,P51114,P40763,Q04637,Q9HAV4,Q06787,Q08209 8 +Gene silencing by rna 0.2615186788408226 0.4095846015963921 0.6821106945204813 1.0 1.0 49 Q8IWR0,P26196,P36507,P42694,P51114,Q5TAX3,Q08209,Q9UIV1,O75569,O60573,Q04637,Q9HAV4,Q9HCE1,Q06787,P40763,Q9UPY3,A5YKK6 17 +Response to iron ii ion 0.7337313432835848 0.4091883392225044 0.6824014511384959 1.0 1.0 2 O00330 1 +Apoptotic process involved in development 0.3760615085963353 0.4091575804807157 0.682424022267941 1.0 1.0 6 P20248 1 +Regulation of translational fidelity 0.3236439916092162 0.4089601270225727 0.682568922720806 1.0 1.0 15 P46782,Q9P2J5,Q9BTE6,Q5ST30,P26640,Q9BW92,Q5JTZ9,P46781,P41252,P49588,Q86U90,Q15031,Q9NSE4,Q99543 14 +Monoubiquitinated protein deubiquitination 0.3162880419312642 0.4086824165420873 0.6827727392785319 1.0 1.0 10 Q9UPT9 1 +Negative regulation of inclusion body assembly 0.3994622049596672 0.4069669617098402 0.6840322537547485 1.0 1.0 5 P54652,P25685,Q00613,P0DMV9 4 +Regulation of protein targeting 0.32443840824366 0.406107159350244 0.6846638655638102 1.0 1.0 26 Q00535,P68036,Q7Z6Z7,P31751,P55786,O14737,P19784 7 +Cell cell signaling by wnt 0.2277531393780535 0.4059970584342623 0.6847447617639082 1.0 1.0 66 O43815,Q96K76,Q96C57,P60953,Q16539,Q9HCK8,Q96QK1,Q13418,P67870,Q96AC1,P40818,P19784,Q13526,Q13043,Q13618,O95071,Q13283,O60493,Q99471,Q96BN8,Q9UGU5,Q9H7S9,Q9GZS3,Q04727 24 +Cellular pigmentation 0.3304822345672413 0.404892077054661 0.6855568424634191 1.0 1.0 9 Q9BXS5,O14617,O00203,Q9H267 4 +Positive regulation of t cell proliferation 0.3152756975711717 0.4043845542102923 0.6859299565662504 1.0 1.0 10 P09429,Q9HCL2 2 +Regulation of dna primase activity 0.4230962406322928 0.4034705043641369 0.6866021290635593 1.0 1.0 4 Q9BRT9,P49643 2 +Smooth muscle cell apoptotic process 0.3447528752501375 0.4022245372570945 0.6875187855817009 1.0 1.0 8 Q96EB6,P42771,P26358 3 +Negative regulation of vasculature development 0.320936638888429 0.4021279762041272 0.6875898446342803 1.0 1.0 14 O75116 1 +Recombinational repair 0.2216263730059263 0.402002139236329 0.6876824519048323 1.0 1.0 61 O60921,P25205,P35244,Q7Z4V5 4 +Regulation of exit from mitosis 0.3740764334358684 0.4018345896592389 0.6878057640308075 1.0 1.0 6 Q8IXJ6,P50748 2 +Regulation of erad pathway 0.3740636883819669 0.4017877585771661 0.6878402319725363 1.0 1.0 6 Q04323,P46379 2 +Fibroblast proliferation 0.3243691977510884 0.4015786729506769 0.6879941280891115 1.0 1.0 18 P21359,Q96IZ0,Q00534,P20248,P14635,Q7Z5K2 6 +Positive regulation of autophagy of mitochondrion 0.3445400054858704 0.4013895315467212 0.6881333555226254 1.0 1.0 8 P27544 1 +Negative regulation of meiotic cell cycle 0.7304477611940328 0.4009152039492513 0.6884825556697518 1.0 1.0 2 Q15645 1 +Regulation of meiotic cell cycle phase transition 0.7304477611940328 0.4009152039492513 0.6884825556697518 1.0 1.0 2 P30307 1 +Positive regulation of translation in response to endoplasmic reticulum stress 0.522544042997917 0.4004912938657086 0.6887946946255639 1.0 1.0 3 O00571,Q04637 2 +Positive regulation of map kinase activity 0.3176950950388046 0.4001170585596757 0.6890703004536451 1.0 1.0 12 O43318,Q16512 2 +Secretory granule localization 0.5222454464019187 0.3996355271364753 0.6894249852880037 1.0 1.0 3 P33176,O60763 2 +Histone ubiquitination 0.3248548628270443 0.3995926669214258 0.6894565584337626 1.0 1.0 21 Q9UPT9,Q6W2J9,O95071,Q5VTR2,Q96FW1 5 +Exploration behavior 0.3973077941188792 0.3993992171219019 0.6895990707159845 1.0 1.0 5 Q05086,Q9HB07 2 +Immune effector process 0.2381053606195058 0.3993633986580742 0.6896254589820094 1.0 1.0 76 Q96EB6,P00813,Q92538,P36915,P00492,P07437,O43318,Q92614,P09429,P52701,O75179,Q96FZ2,Q16512,Q9UQ84,P40763,P22681 16 +Outer mitochondrial membrane organization 0.3971431482164287 0.3988234718617989 0.6900232808829365 1.0 1.0 5 O14737 1 +Mitotic recombination 0.3155345668099703 0.3978886138773059 0.690712293427515 1.0 1.0 11 P18074,Q9Y620 2 +Regulation of erythrocyte differentiation 0.3198817718462604 0.3975959358652839 0.6909280567883431 1.0 1.0 14 Q16539,Q00534,Q15648,Q99873,P40763 5 +Interleukin 6 production 0.3209002219046389 0.3970562500359333 0.6913259810929695 1.0 1.0 15 P17655,P40763,P09429,Q06124 4 +Negative regulation of small gtpase mediated signal transduction 0.3168953162741564 0.3967237190697634 0.6915712072318465 1.0 1.0 12 P21359,P16949,O95630 3 +Positive regulation of lipase activity 0.3134034853335492 0.3964945109358465 0.691740256419362 1.0 1.0 10 Q9Y263 1 +Positive regulation of helicase activity 0.3963068805484752 0.3959049020681509 0.692175184598653 1.0 1.0 5 P20585 1 +Regulation of histone ubiquitination 0.3128037320721509 0.3939831579232404 0.693593473727764 1.0 1.0 10 Q5VTR2,Q96FW1 2 +Negative regulation of intracellular protein transport 0.327275069271764 0.3919091252328614 0.6951253603043164 1.0 1.0 9 P21359,P61960 2 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.3941101398806077 0.3882844112790256 0.6978055720870997 1.0 1.0 5 P21359 1 +Response to growth factor 0.2716091122697067 0.3880487114432815 0.697979985971164 1.0 1.0 109 O00560,Q9UQB8,P27695,Q16539,P46940,Q6IBS0,O14737,O75116,Q13546,Q7L576,Q53EL6,P22681,Q9UPN9,Q9Y3F4,Q9HCM4,P19174,P49427,P48506,O43318,P08238,P51452,P35241,Q15648,Q96AC1,Q96TA1,P40763,P40818,Q96EB6,Q9C0C9,Q13526,Q8N0X7,Q13464,Q8IXJ6,Q05086,P20248,Q06124,O43237,P28482,Q96B36,Q04206,P50570,Q9H4M9,Q93008,P46109,P42574,P48507 46 +Asymmetric cell division 0.3556132473791725 0.3874527263438795 0.6984210759951024 1.0 1.0 7 Q92974,Q96N67 2 +Androgen receptor signaling pathway 0.3195757800200975 0.3871332806028305 0.6986575405074784 1.0 1.0 16 Q16512,Q9UER7,Q05086 3 +Negative regulation of transferase activity 0.2255125606180491 0.387012175711121 0.6987471940793897 1.0 1.0 66 P60866,Q9Y3I1,P41240,P42771,Q16512,P22681,P27544,P62081,O60566,O43684,P47897,Q96BK5,P31689,Q96EB6,P21359,Q9UL15,Q14240,Q96B36,O95373,P42574,P62841 21 +Fat cell differentiation 0.3157082838251661 0.3853899421552444 0.6999485331933999 1.0 1.0 30 Q96EK7,Q3SYG4,Q8N4Q0 3 +Positive regulation of neurogenesis 0.286401489055806 0.3850784121928172 0.7001793216409524 1.0 1.0 42 Q14999,Q9UQB8 2 +Positive regulation of nervous system development 0.286401489055806 0.3850784121928172 0.7001793216409524 1.0 1.0 42 Q14999,Q9UQB8 2 +Regulation of muscle cell differentiation 0.3198671290988301 0.3845974985491135 0.700535647708691 1.0 1.0 26 Q96EB6,P26358,O75179,P67809,Q86TU7 5 +Axoneme assembly 0.5166903077847836 0.3838737709579934 0.7010720074973971 1.0 1.0 3 Q15555 1 +Kidney morphogenesis 0.3400119617224809 0.3838199422826652 0.7011119062781725 1.0 1.0 8 O95747,O75844,Q9Y5V3,Q13418,P42224,P31277,Q12959 7 +Scarna localization to cajal body 0.3927979804432016 0.383764740896196 0.701152823393234 1.0 1.0 5 Q9BUR4 1 +Regulation of peptidyl serine phosphorylation 0.3207305302237739 0.3818229357462231 0.7025927051286824 1.0 1.0 23 P35080,Q99996,Q96N67,Q13153,Q13043,P07900,Q9UHD2,Q92600,P08238,Q04637,Q16512 11 +Gtp metabolic process 0.3130788216114445 0.3807298702434499 0.7034037019809369 1.0 1.0 12 P15531,P20839,P12268,Q7Z2Z2,P22392 5 +Regulation of histone modification 0.2224859768797217 0.3804915081611797 0.7035805989148369 1.0 1.0 64 Q96EB6,Q01105,Q03164,Q6W2J9,O95071,P18615,P26358,Q5VTR2,Q96FW1,Q06787 10 +Positive regulation of dopamine receptor signaling pathway 0.7217910447761224 0.3795023026404051 0.7043148946857494 1.0 1.0 2 O14744 1 +Regulation of dopamine receptor signaling pathway 0.7217910447761224 0.3795023026404051 0.7043148946857494 1.0 1.0 2 O14744 1 +Inflammasome complex assembly 0.5150791280979472 0.3793595725042211 0.7044208672694383 1.0 1.0 3 Q8IXJ6,O00571 2 +Positive regulation of filopodium assembly 0.3532780482637433 0.3787860848343846 0.7048467214410024 1.0 1.0 7 O00401,P60953,Q9H6U6,Q16658,Q06787 5 +Animal organ formation 0.3532360129015962 0.3786309166436638 0.7049619604386561 1.0 1.0 7 P28482,Q8NC56 2 +Negative regulation of histone acetylation 0.3531987826572808 0.3784935108338127 0.7050640134742499 1.0 1.0 7 Q01105 1 +Dna catabolic process endonucleolytic 0.367608956695852 0.378381536749371 0.7051471819702944 1.0 1.0 6 P27695 1 +Morphogenesis of a polarized epithelium 0.316308564595768 0.3775290459923228 0.7057804830112293 1.0 1.0 15 Q92796,P15311,O95487,P43034 4 +Receptor clustering 0.3135365406786289 0.3764268362235918 0.7065995982201863 1.0 1.0 13 P46109,Q00535,Q92796 3 +Positive regulation of cell migration involved in sprouting angiogenesis 0.5138847417139486 0.3760300074585244 0.706894587670607 1.0 1.0 3 P09601,O00443 2 +Phosphorylation of rna polymerase ii c terminal domain 0.3523466895833029 0.375355096544476 0.7073963953247626 1.0 1.0 7 Q8WUA2,Q92759,O75909 3 +Positive regulation of muscle tissue development 0.3899479657538078 0.3740322481197388 0.708380324087488 1.0 1.0 5 P41440 1 +Positive regulation of skeletal muscle tissue development 0.3899479657538078 0.3740322481197388 0.708380324087488 1.0 1.0 5 P41440 1 +Neuroepithelial cell differentiation 0.4135306996132503 0.3719371211028064 0.7099396660019714 1.0 1.0 4 P07437,Q9P287 2 +In utero embryonic development 0.2673799387189091 0.3714430651750056 0.7103075547586637 1.0 1.0 107 P62993,P00813,P43686,O43772,P17655,O95067,P18074,Q9H0G5,P31350,Q9HCK8,Q13619,Q9NR09,Q8IWS0,Q96AY3,Q15648,Q99873,P35579,Q9ULT8,Q14790,Q13618,Q08J23,Q6GQQ9,P20248,P61201,P28482,Q15293,P26572,Q6W2J9,O60568,Q9NPQ8,Q01968,P67809,A5YKK6,P14635,Q9BRT9,P20290 36 +Pteridine containing compound metabolic process 0.3179300909869322 0.371392482334549 0.7103452240595751 1.0 1.0 19 P41440,Q99707,P00374,Q8IYS1,P31939,Q9NRN7 6 +Intrinsic apoptotic signaling pathway in response to dna damage 0.3180684508972349 0.3712904067293198 0.7104212424415564 1.0 1.0 24 Q96EB6,P13693,Q96K76,P46379,P52701,Q96RU2 6 +Interferon beta production 0.3132934877311879 0.3698767341050105 0.7114743374971793 1.0 1.0 14 P41440,Q9BUI4,O14802,Q9UHD2,Q06124 5 +Regulation of tau protein kinase activity 0.7176119402985106 0.369376201960742 0.7118473338331321 1.0 1.0 2 P07900 1 +Positive regulation of tau protein kinase activity 0.7176119402985106 0.369376201960742 0.7118473338331321 1.0 1.0 2 P07900 1 +Regulation of calcium ion dependent exocytosis 0.3880036714841198 0.3674598434360832 0.7132760401750975 1.0 1.0 5 Q15042 1 +Cap dependent translational initiation 0.7167164179104508 0.3672245360898696 0.7134515387669151 1.0 1.0 2 Q04637 1 +Apoptotic dna fragmentation 0.4118876941457434 0.3666428526441281 0.7138854390994647 1.0 1.0 4 O95831,Q00613,Q9UPY3 3 +Utp metabolic process 0.3876411706219361 0.366240557302584 0.714185581004402 1.0 1.0 5 P15531,P27708 2 +Positive regulation of nuclease activity 0.5103015825619659 0.366128421039514 0.7142692507854285 1.0 1.0 3 P12004,P26583 2 +Positive regulation of cellular amide metabolic process 0.2240749305006767 0.3659734877224122 0.7143848589761814 1.0 1.0 67 Q7Z478,Q6PKG0,P14618,P42574,P62701,Q567V2,Q13144,Q96P11,P63241,P20248,O75534,P13639,O75116,P67809,Q06787 15 +Viral translational termination reinitiation 0.3639134817078494 0.3652681218695157 0.7149112719107373 1.0 1.0 6 O75821,Q9Y262,Q14152 3 +Nadph regeneration 0.3205145018469044 0.3652197086369512 0.7149474075734654 1.0 1.0 9 P11413,P18669,O95336 3 +Cerebellar purkinje cell layer morphogenesis 0.5099565605410401 0.3651819554286883 0.7149755870317427 1.0 1.0 3 O15020 1 +Antigen processing and presentation of lipid antigen via mhc class ib 0.7158208955223913 0.3650793471124544 0.7150521771018354 1.0 1.0 2 O00203 1 +Zinc ion homeostasis 0.7158208955223913 0.3650793471124544 0.7150521771018354 1.0 1.0 2 O00203 1 +Regulation of nk t cell differentiation 0.7158208955223913 0.3650793471124544 0.7150521771018354 1.0 1.0 2 O00203 1 +Nk t cell differentiation 0.7158208955223913 0.3650793471124544 0.7150521771018354 1.0 1.0 2 O00203 1 +Regulation of transporter activity 0.2757582453373365 0.3648521301503907 0.7152217891893149 1.0 1.0 44 Q03164,Q99996,P42858,P78417,P35754 5 +Regulation of system process 0.2217037822996146 0.3648258765325965 0.715241387800355 1.0 1.0 65 P78417,P11413,P00813,Q99996,Q86TU7,Q9UQB8,Q9Y5X3,Q06124,O75116,P28161,Q06787,Q08209 12 +Endocrine hormone secretion 0.5097182104260448 0.3645288313520806 0.7154631483308298 1.0 1.0 3 Q06124 1 +Bone remodeling 0.349189872009056 0.363836089701539 0.7159804112685264 1.0 1.0 7 P21359,Q9UBB6 2 +Bone resorption 0.349189872009056 0.363836089701539 0.7159804112685264 1.0 1.0 7 P21359,Q9UBB6 2 +Regulation of organic acid transport 0.3070893181475879 0.3630580883190683 0.716561492193803 1.0 1.0 11 P31751 1 +Protein modification by small protein conjugation or removal 0.374955605226666 0.3589910443342798 0.7196017889297068 1.0 1.0 235 Q00535,Q15369,Q7Z6Z7,P51784,Q96DY7,O00487,Q14999,O60566,P49427,Q96RU2,Q86VP6,Q13617,Q99627,Q9C0C9,Q9UPT9,Q9Y263,Q5TAQ9,Q9Y4B6,P61086,P55786,Q05086,O60678,O95376,O95352,Q96BN8,O94822,Q93008,Q2VPK5,P52888,Q14527,Q01804,Q9Y3I1,Q9UER7,P22314,P22681,Q9Y314,P61081,P48506,P45974,P61960,Q96BK5,Q15386,Q8N806,P40818,Q9UL15,Q9UJX4,P15880,O95628,O94966,Q6W2J9,A0AVT1,Q96JP5,P62841,Q16763,Q5T4S7,Q96K76,Q92990,Q93034,Q9NT62,Q14694,Q14258,Q9H1B7,Q9UPN9,Q13619,Q9NR09,Q9UBT2,P68036,O43684,Q04323,P19474,P61962,P31689,P49407,Q96EB6,Q8TBC4,Q13618,Q6GQQ9,Q9Y5K5,Q13564,Q7Z7E8,Q86UV5,Q92905,O75150,P07900,Q5VTR2,Q13501,O95630,P60866,Q13309,P62081,Q96FW1,Q8IWV7,Q9Y5A7,Q9UII4,Q9ULT8,O95071,P61201,Q7L5N1,Q15020 99 +Regulation of erbb signaling pathway 0.3060292466386648 0.3588029532797721 0.7197425031878615 1.0 1.0 11 Q9Y5X3,P22681 2 +Extrinsic apoptotic signaling pathway 0.2704659285243956 0.356047865017519 0.7218047197165463 1.0 1.0 45 P21359,Q14790,Q9NR09,Q9P0J0,Q99504,P42858,P61289,Q9UER7 8 +Histone mrna catabolic process 0.3180249333858935 0.3556308735341351 0.7221170195124351 1.0 1.0 9 Q92900,Q5TAX3,P05455 3 +Negative regulation of actin nucleation 0.5064198268139822 0.3555513346853223 0.7221765942547198 1.0 1.0 3 P60983,Q9BR76 2 +Vesicle localization 0.2126604530038767 0.355243538062242 0.7224071503566656 1.0 1.0 58 Q00535,Q7Z460,O00743,O00401,O15027,Q9Y6B6,P33176,Q9Y2T2,Q13618,Q9NR31,Q92538,P50570,Q92905,Q92734,P43034,O00203,P42858,Q14204,P27695 19 +Rna mediated gene silencing by inhibition of translation 0.3609526641639778 0.3549174827504608 0.7226514106894264 1.0 1.0 6 P26196,P40763,Q04637 3 +Telomere maintenance 0.2226968292068655 0.3549018852732375 0.7226630960566003 1.0 1.0 67 P41440,P35251,Q9BUR4,Q92900,Q96HR8,Q9UQ84,P35244,O60921,P08238,P39748,P27694,Q96BK5,Q9UPR3,P49368,P50991,P49750,P40227,Q8IZH2,P28482,P17987,Q13535,Q99832,P07900,Q9Y4R8,P13010,P48643,P27695 27 +Maintenance of apical basal cell polarity 0.5060764570745111 0.3546233030858966 0.7228718160310459 1.0 1.0 3 Q8WUM4 1 +Hippo signaling 0.346596502003543 0.3545025691142014 0.7229622790152876 1.0 1.0 7 Q8TD19,Q16539 2 +Regulation of programmed necrotic cell death 0.3027538556717342 0.3531108040476334 0.7240053735035266 1.0 1.0 10 P55212,Q9NX46,Q14790 3 +Regulation of protein containing complex assembly 0.2708557084282658 0.3526429276695873 0.7243561508598342 1.0 1.0 113 P47756,Q9Y295,Q9UQB8,Q7Z460,Q6IBS0,Q16512,P47755,O15020,Q14008,Q99996,Q9Y6B6,P35611,P09429,P16949,Q9BTW9,Q86VP6,P35241,Q96AC1,Q8IXJ6,P04350,Q14203,Q9UEY8,Q14155,Q06124,Q04637,Q13535,Q9NR31,Q13153,P36404,P07900,Q15058,P35080,P07737,Q15691,P54920,Q9BPX3 36 +Positive regulation of cellular protein catabolic process 0.2530255971373025 0.3523389083589611 0.7245841119464218 1.0 1.0 49 P62191,P43686,P62333,P53350,O60826,Q06787,Q96QK1,P46379,P48506,P45974,O75832,O43765,P35241,Q9Y5A7,Q9ULT8,O14965,Q8IXJ6,O95376,Q9Y4X5,O75150,P07900,Q9BW61,P15311,P62195 24 +Vitamin transport 0.3169300870948058 0.3514558541390764 0.7252463859270359 1.0 1.0 9 P41440 1 +Regulation of cytoplasmic transport 0.3086826116421411 0.3510983561191948 0.7255145611714067 1.0 1.0 14 P36507,O60493,O75165,P35241,P28482,Q13614 6 +Neuroblast division 0.5041721056786966 0.3494989932182407 0.7267147265180356 1.0 1.0 3 Q96N67 1 +Asymmetric neuroblast division 0.5041721056786966 0.3494989932182407 0.7267147265180356 1.0 1.0 3 Q96N67 1 +Regulation of telomere capping 0.3161830690996089 0.3486220672544604 0.7273730586483396 1.0 1.0 9 P18887,O60934,Q14103,P27361,Q15554,P28482,Q92878,Q93009 8 +Positive regulation of gliogenesis 0.3159726335044232 0.3478259718109582 0.7279708834413918 1.0 1.0 9 Q15382 1 +Response to insulin 0.2115958702255531 0.3466123682872876 0.7288825527725806 1.0 1.0 58 Q96EB6,O60343,O15357,Q9UQB8,P14618,P31751,P11802,Q9Y5X3,P07741,Q06124,P43490 11 +Microtubule anchoring 0.3010357617128736 0.3463595135089714 0.7290725477650841 1.0 1.0 10 Q15154,Q7Z460,Q9P287,Q14203,Q8TD16,Q9UIS9 6 +Post translational protein modification 0.3044914104205825 0.3459892326184451 0.7293508067207302 1.0 1.0 12 O60725,Q92905,Q9Y4P8,P61081,Q32P28,O95352 6 +Positive regulation of erbb signaling pathway 0.3582947966062816 0.3457466448738213 0.7295331260686027 1.0 1.0 6 P22681 1 +Lipopolysaccharide mediated signaling pathway 0.3150103460251016 0.3441978504455966 0.7306974987528432 1.0 1.0 9 Q8WTV0,P28482 2 +Regulation of developmental growth 0.2268663091534938 0.3428537045489035 0.7317085214513768 1.0 1.0 54 P11413,Q9Y263,Q00535,Q9HCL2,Q8N0X7,P50570,P43034,Q99956,Q9C0B1,P11802,P40763,Q9P265,Q14353 13 +Calcium mediated signaling 0.311059183941639 0.3426232596151213 0.7318819014564595 1.0 1.0 19 P00813,P19174,P42858,P78417,Q08209 5 +Cerebellar cortex formation 0.3804179033070055 0.3423527864686777 0.7320854149767162 1.0 1.0 5 Q06124 1 +Muscle hypertrophy 0.3109841475849855 0.3423160697694328 0.7321130433673129 1.0 1.0 19 O75116,Q08209 2 +Secretory granule organization 0.4039791678249982 0.341680280244335 0.7325915139973691 1.0 1.0 4 P22059 1 +Neural nucleus development 0.3090574845342996 0.3398667951771264 0.733956843331149 1.0 1.0 17 P11413,P27348,O15027,P12277,P14854,O95487 6 +Cholesterol catabolic process 0.7050746268656769 0.3398500970823189 0.7339694188427002 1.0 1.0 2 Q8WTV0 1 +Mammary gland development 0.31083662756068 0.3389251481148191 0.7346661190519272 1.0 1.0 21 P11172,P15531,P31751,P07741,P49327,P61201,P28482 7 +Intestinal epithelial cell differentiation 0.5001492982980077 0.3388014841285359 0.7347592831629557 1.0 1.0 3 Q92908,P04818 2 +Neuronal stem cell population maintenance 0.3562462641960494 0.3387576160963302 0.734792332738208 1.0 1.0 6 Q9NZI8,Q15154,Q9BXP5,Q9BXW9,Q9UIS9 5 +Positive regulation of dephosphorylation 0.3055387498056577 0.3385987028983404 0.7349120598790169 1.0 1.0 14 Q8IV63,Q13526,Q15257,Q69YH5,Q14738,P08238 6 +Regulation of lipid localization 0.3105010934459976 0.3383300718180316 0.7351144644586043 1.0 1.0 24 Q96EB6,Q8WTV0,Q9H4M9,Q9Y6B6,P31751,Q9BZF3,Q06124 7 +Lamellipodium assembly 0.3104884582943825 0.3374870271630986 0.7357497899517931 1.0 1.0 21 P47756,Q9Y2A7,P50570,P61160,Q9H4A6,P60953,Q6IBS0,Q14155,Q16658,Q7L576 10 +Negative regulation of gliogenesis 0.3558442928898415 0.3373943991858384 0.7358196061993598 1.0 1.0 6 Q8IXJ6,P21359 2 +Ribose phosphate biosynthetic process 0.2346072585349397 0.3373542252995923 0.7358498870379495 1.0 1.0 80 P00813,P11172,P27708,P22392,O60256,P11413,Q06203,P30520,P04075,P49915,P00492,P53396,P31939,O00154,O00330,P20839,Q01433,P07741,Q13057,Q9BZX2,P15531,P17812,Q9NVE7,P06737,P30566,O15067 26 +Response to uv b 0.7032835820895558 0.3357387741112898 0.7370678637739256 1.0 1.0 2 P43246 1 +Response to lipoteichoic acid 0.7032835820895555 0.3357387741112889 0.7370678637739263 1.0 1.0 2 Q16539 1 +Regulation of mrna binding 0.3404952490817783 0.3330180851727413 0.7391206315983856 1.0 1.0 7 Q06787,O15371,Q04637 3 +Positive regulation of response to biotic stimulus 0.2959236116191717 0.3325213302688494 0.739495635920806 1.0 1.0 35 Q9BUI4,Q9NUD5,Q9UHD2,Q15648,P55212,O43318,P09429,O75179,Q9NW08,Q16512 10 +Positive regulation of protein sumoylation 0.4006433861964492 0.3314167182574319 0.7403297384379071 1.0 1.0 4 Q9UBT2,Q9UBE0 2 +Nephron morphogenesis 0.3399103139013552 0.3309940261684135 0.7406489979001587 1.0 1.0 7 O95747,Q9Y5V3,Q13418,P42224,P31277,Q12959 6 +S adenosylmethionine metabolic process 0.3533068052888886 0.3288517104599783 0.7422677754704259 1.0 1.0 6 Q9NZL9,P23526,Q86W50 3 +Cell maturation 0.3082165231591642 0.3287130201443569 0.7423726120997396 1.0 1.0 24 P11413,Q15645,O14965,Q8NHU6,Q5TAX3,P18074 6 +Purine nucleoside diphosphate catabolic process 0.6994029850746306 0.3269243170271217 0.7437251284632613 1.0 1.0 2 Q96DE0 1 +Negative regulation of amyloid beta clearance 0.4950731561660262 0.3255535977516135 0.7447621246680345 1.0 1.0 3 P04035,Q16850 2 +Nervous system process 0.2608367796513313 0.3243897394820396 0.7456429868354264 1.0 1.0 107 P21359,P78417,Q99996,Q8N0X7,P78559,Q9UQB8,Q99504,P42858,Q13432,Q05086,Q00169,O75569,Q15042,P49419,O75116,Q9NPQ8,Q08209,Q3SYG4 18 +Cerebral cortex neuron differentiation 0.3983026360666069 0.3243112255344934 0.7457024218375479 1.0 1.0 4 P00492 1 +Chromosome organization involved in meiotic cell cycle 0.3062531570149132 0.3232615770354027 0.7464971502317499 1.0 1.0 19 Q6IBW4,O60566,Q15645,P42695,P46379,O95347,Q15021,Q15003,Q9NTJ3 9 +Response to epinephrine 0.6970149253731379 0.3215641218592157 0.7477829278572632 1.0 1.0 2 Q8IXJ6 1 +Cellular response to epinephrine stimulus 0.6970149253731379 0.3215641218592157 0.7477829278572632 1.0 1.0 2 Q8IXJ6 1 +Spermatid nucleus differentiation 0.373723850282424 0.3209302586315162 0.7482632427693854 1.0 1.0 5 Q14997 1 +Thyroid gland development 0.4925607879198894 0.3191019971605314 0.7496491692578509 1.0 1.0 3 P28482 1 +Positive regulation of histone modification 0.2831697422661773 0.3175318058215212 0.7508401096184589 1.0 1.0 39 Q96EB6,Q03164,P18615,P26358,Q06787 5 +Calcium ion transport into cytosol 0.3021621237607215 0.3164314902136615 0.7516750182146823 1.0 1.0 16 P78417,P19174,P27695,P42858 4 +Regulation of calcium ion transmembrane transport 0.3053812997654849 0.3162131201182476 0.7518407498878668 1.0 1.0 22 P11413,P19174,P42858,P78417,P28161,Q06787,P27695 7 +Placenta development 0.3041789252204748 0.3155072853170058 0.752376520449286 1.0 1.0 26 P00813,Q9ULT8,Q14790,Q9NR09,P20248,P62753,P28482,Q14999 8 +Development of secondary female sexual characteristics 0.4910937299573614 0.3153673380836734 0.7524827628990898 1.0 1.0 3 Q15648 1 +Development of secondary sexual characteristics 0.4910937299573614 0.3153673380836734 0.7524827628990898 1.0 1.0 3 Q15648 1 +Membrane invagination 0.2946483021625459 0.3148507261036684 0.752874995038457 1.0 1.0 11 P35579,O60493,Q14185 3 +Positive regulation of endothelial cell apoptotic process 0.4907696814717096 0.3145456801517466 0.7531066278923055 1.0 1.0 3 P19174 1 +Chloride transmembrane transport 0.3209576645040364 0.3141640030648239 0.7533964809472846 1.0 1.0 8 Q9UHG3 1 +Skin epidermis development 0.2989990188618044 0.3134143036816868 0.7539659184940222 1.0 1.0 14 P21359,P18074,Q08J23 3 +Positive regulation of autophagy 0.2874179928125474 0.3133211579306219 0.7540366771207598 1.0 1.0 37 Q96EB6,Q6PKG0,P42858,O43318,P09429,P19474,Q15042,P27544 8 +Centrosome separation 0.3944020388677097 0.3126507312977363 0.7545460308909313 1.0 1.0 4 O14965,P43487 2 +Ncrna export from nucleus 0.348016031059548 0.3113945418342169 0.7555007027778555 1.0 1.0 6 Q9H814 1 +Cellular response to heat 0.2994760813452607 0.3108519168185832 0.7559131995195381 1.0 1.0 30 Q96EB6,P21359,P05198,P07900,Q9UER7,P08238,Q99615,Q13535 8 +Cerebellar purkinje cell layer development 0.3338359939123128 0.3103544915556031 0.7562913971091783 1.0 1.0 7 O15020,Q15058 2 +Positive regulation of peptidyl tyrosine phosphorylation 0.3004781103765013 0.3100176848498471 0.756547507900843 1.0 1.0 16 Q13432,Q06124,Q92796 3 +Negative regulation of receptor internalization 0.3699560875097674 0.3091860633834756 0.757179994687714 1.0 1.0 5 Q13614,Q15334 2 +Endothelin receptor signaling pathway 0.6913432835820934 0.3090317794414545 0.7572973526966096 1.0 1.0 2 P46109 1 +Regulation of synapse structural plasticity 0.6913432835820934 0.3090317794414545 0.7572973526966096 1.0 1.0 2 Q14012 1 +Glial cell apoptotic process 0.3690287944481192 0.3063310565834832 0.7593525953224292 1.0 1.0 5 P42574 1 +Negative regulation of dna templated transcription elongation 0.3046069701844389 0.3062965280083187 0.7593788825144323 1.0 1.0 9 P18615 1 +Response to interleukin 7 0.2903443697102586 0.3059839227387023 0.7596168868761606 1.0 1.0 10 P67809,P51858,P31939 3 +Negative regulation of peptidyl lysine acetylation 0.304268545109908 0.3051052975806213 0.7602859565689049 1.0 1.0 9 Q01105 1 +Positive regulation of cell cycle g2 m phase transition 0.2943697363512842 0.3015438032437383 0.7629998532460665 1.0 1.0 13 P14635,P23921,P30307,P11802 4 +Regulation of helicase activity 0.302876656156476 0.3002342844078022 0.7639984554668258 1.0 1.0 9 Q96EB6,P20585 2 +Substantia nigra development 0.2965951870903177 0.2997029761362555 0.7644037282783025 1.0 1.0 15 P11413,P27348,Q8IXJ6,O15027,P12277,P14854 6 +Necroptotic signaling pathway 0.686865671641796 0.2993372300938483 0.7646827505807048 1.0 1.0 2 P49327 1 +Positive regulation of response to oxidative stress 0.6868656716417949 0.299337230093846 0.7646827505807066 1.0 1.0 2 Q96IZ0 1 +Positive regulation of response to reactive oxygen species 0.6868656716417949 0.299337230093846 0.7646827505807066 1.0 1.0 2 Q96IZ0 1 +Actin cytoskeleton reorganization 0.2987171495602575 0.2988858288277154 0.7650271601148015 1.0 1.0 28 P35579,P15311,Q00535,Q13153,Q9UQB8,Q9H6U6,Q9Y5K6,Q16512,Q9UL63 9 +Positive regulation of locomotion 0.2396874653017001 0.2983404149949957 0.765443361220409 1.0 1.0 90 Q15555,Q96Q89,O75116,Q16512,Q8WTV0,Q96N67,Q9UH99,P19174,O00429,P09429,Q96AC1,P40763,Q08209,Q96EB6,Q9Y263,P31751,Q14185,P20248,Q14155 19 +Positive regulation of cell division 0.2972986633887612 0.2981219069734458 0.7656101220217928 1.0 1.0 16 Q99741,Q8IXJ6,Q13618,Q9H8V3,Q15058,Q96Q89,P67809,Q16513 8 +Meiosis i cell cycle process 0.3006917374473239 0.2977513403341648 0.7658929556441672 1.0 1.0 22 Q15645,O14965,P46379,O95067,P30307,Q9Y620 6 +Dna catabolic process 0.31608851674641 0.2975493809223742 0.766047113562804 1.0 1.0 8 Q9GZR2,Q9H0D6,Q00613,O00273,O95831,Q9UPY3,P27695 7 +Nerve growth factor signaling pathway 0.4837264855180742 0.2969823688279672 0.7664799698484042 1.0 1.0 3 Q9Y4G8,P31146 2 +Negative regulation of jun kinase activity 0.6856716417910502 0.2967820504120954 0.766632910095389 1.0 1.0 2 P31689 1 +Folate transmembrane transport 0.6847761194029913 0.2948740136154752 0.7680901238933959 1.0 1.0 2 P41440 1 +Folic acid transport 0.6847761194029913 0.2948740136154752 0.7680901238933959 1.0 1.0 2 P41440 1 +Intermediate filament based process 0.2872531418312337 0.2948537225793638 0.7681056250635463 1.0 1.0 10 Q9UPN3,P48729,P08670,Q03001,Q15149,Q96RT1,P48681,P58107,P15924 9 +Cellular response to interleukin 1 0.2890975356421263 0.2946108387892413 0.7682911813348654 1.0 1.0 11 Q92900,O43318,Q14694,Q01804 4 +Glucose 6 phosphate metabolic process 0.2886489504930098 0.2930106711345017 0.7695139951121628 1.0 1.0 11 P11413,P18669,O95336 3 +Nonribosomal peptide biosynthetic process 0.3285554121145344 0.2929884722888176 0.7695309630332088 1.0 1.0 7 P48506,Q8WUX2 2 +Pyrimidine nucleotide catabolic process 0.6835820895522426 0.2923411272695224 0.7700258165046021 1.0 1.0 2 P33316 1 +T cell differentiation 0.2977040041749009 0.2916412141568993 0.7705609602583043 1.0 1.0 27 Q6IBW4,P00491,P00813,Q00534,P09429,P62753,P40763,P24390 8 +Regulation of voltage gated calcium channel activity 0.3641752819479139 0.2916197578222529 0.7705773671980483 1.0 1.0 5 Q06787 1 +Positive regulation of epithelial cell proliferation 0.2988451688139045 0.2914288208815282 0.7707233747959219 1.0 1.0 21 Q96EB6,P21359,P19174,P15531,P09429,Q15648,P40763 7 +Response to thyroid hormone 0.3141088125601481 0.2909397936973675 0.7710973661078815 1.0 1.0 8 P48506,Q15648,Q9Y376,P48507 4 +Neural tube development 0.2974674630698804 0.2906942383858907 0.7712851785092998 1.0 1.0 27 P11586,Q13572,P62081,P21359,Q9ULT8,Q13043,Q92990,O60568,P25440,Q96Q89,P42574,P07737,O95487 13 +Non canonical wnt signaling pathway 0.3867980884109788 0.29058190051332 0.7713711043367564 1.0 1.0 4 P60953,P63000,Q13308 3 +Regulation of cell migration involved in sprouting angiogenesis 0.3867980884109751 0.290581900513309 0.7713711043367648 1.0 1.0 4 P09601,O00443,P04083 3 +Negative regulation of calcium mediated signaling 0.4804419229620877 0.2889876023078114 0.7725908649149815 1.0 1.0 3 Q9UHD1,P42345 2 +Negative regulation of calcineurin mediated signaling 0.4804419229620877 0.2889876023078114 0.7725908649149815 1.0 1.0 3 Q9UHD1,P42345 2 +Necrotic cell death 0.2969147900028925 0.2875180759973364 0.7737156633225211 1.0 1.0 19 Q13572,Q14790,Q9NX46,O00429,P55212,P06737,P49327 7 +Negative regulation of leukocyte apoptotic process 0.3403551819490167 0.2869940908052432 0.7741168448583593 1.0 1.0 6 P00813 1 +Negative regulation of lymphocyte apoptotic process 0.3403551819490167 0.2869940908052432 0.7741168448583593 1.0 1.0 6 P00813 1 +Regulation of leukocyte chemotaxis 0.2942001375147074 0.2868017017314703 0.7742641598643576 1.0 1.0 16 P09429,P30046,O00429 3 +Nucleoside phosphate biosynthetic process 0.2408685646238269 0.2855982157958018 0.7751858701540111 1.0 1.0 93 P00813,P11172,P27708,P22392,P31350,O60256,P23921,Q06203,P30520,P04075,P49915,P00492,P33316,P53396,Q969G6,P31939,O00154,O00330,P20839,Q01433,P07741,P04183,Q13057,P43490,P11586,Q9BZX2,P15531,P17812,Q9NVE7,P30566,O15067 31 +Fas signaling pathway 0.6802985074626917 0.2854417734660286 0.775305707485827 1.0 1.0 2 P49327 1 +Mesonephric tubule morphogenesis 0.33980872683801 0.2852942567805515 0.7754187125333156 1.0 1.0 6 O95747,Q9Y5V3,Q13418,P31277,Q12959 5 +Tube formation 0.2968898408277083 0.2844231214835522 0.776086141976738 1.0 1.0 25 P11586,P62081,Q9ULT8,P63104,Q13043,Q92990,Q9H6U6,P25440,Q96Q89,P42574,P07737,O95487 12 +Vitamin metabolic process 0.2919518113970898 0.2844020780125243 0.7761022667004913 1.0 1.0 31 Q9Y617,Q9H2D1,P41440,P11166,Q8NFF5,Q99707,O00764,P48506,P00374,O60678,Q96EY8,Q8IYS1,P78417,Q969G6,Q9NRN7 15 +Regulation of autophagy of mitochondrion 0.2945326952960553 0.2843958136033471 0.776107066871508 1.0 1.0 17 P27544,O00429,P42858 3 +Regulation of dephosphorylation 0.2853511652305214 0.2840681769597087 0.7763581338952168 1.0 1.0 35 Q8IV63,Q13614,P31946,Q13526,Q5H9R7,Q15257,Q69YH5,Q14738,P42858,P08238,P67870,O75116,Q9UPR3,P78318 14 +Positive regulation of ossification 0.3393079676857763 0.2837413982337137 0.7766085667755867 1.0 1.0 6 P20248 1 +Negative regulation of viral process 0.2963581024717174 0.2835126036590777 0.7767839215237606 1.0 1.0 20 P19474,P78362,Q14258 3 +Positive regulation of receptor mediated endocytosis 0.2859280384969478 0.2834204776018159 0.7768545327987417 1.0 1.0 11 O00401,Q06787,P50570,P22681 4 +Microtubule organizing center organization 0.2643166874385674 0.2834013900512276 0.7768691629432061 1.0 1.0 43 Q96EB6,Q14008,P43487,O14980,Q7Z4H7,Q7Z460,Q9H6U6,O14965,P36404,P43034,Q14203,O75351,Q9BT25,Q8NI35,O75116,Q9UIS9,P52732 17 +Somatic diversification of immune receptors 0.2953578680689571 0.282333644243084 0.7776876900970247 1.0 1.0 27 Q9Y3Z3,P20585,P09429,P52701,Q96FZ2,Q9UQ84,P18858 7 +Response to muscle stretch 0.3607048340927022 0.2813433034289351 0.7784470996958048 1.0 1.0 5 Q04206,Q16539 2 +Regulation of wnt signaling pathway 0.241288901830567 0.2810361286369247 0.7786826894013474 1.0 1.0 49 Q9HCK8,Q04727,Q13526,Q96QK1,Q96K76,Q13043,Q96BN8,Q96C57,O95071,Q16539,Q9UGU5,Q13283,Q13418,Q9H7S9,O60493,Q99471,P40818 17 +Telomere organization 0.2148508246151797 0.2803222479947139 0.7792302833293712 1.0 1.0 69 P41440,P35251,Q9BUR4,Q92900,Q96HR8,Q9UQ84,P35244,O60921,P08238,P39748,P27694,Q96BK5,Q9UPR3,P49368,Q8IXJ6,P50991,P49750,P40227,Q8IZH2,P28482,P17987,Q13535,Q99832,P07900,Q9Y4R8,P13010,P48643,P27695 28 +Cell activation involved in immune response 0.2752865552666474 0.2797607619325956 0.7796610574903318 1.0 1.0 39 P00813,Q92538,P09429,P52701,Q96FZ2,Q9UQ84,P40763,P22681 8 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.337842782189706 0.27922449789966 0.7800725444005798 1.0 1.0 6 Q9GZT9 1 +Protein monoubiquitination 0.2958446348019282 0.2791202893028495 0.7801525130490035 1.0 1.0 23 Q6W2J9,Q7Z6Z7,Q14258,Q5VTR2,P19474,P22681 6 +Regulation of translational elongation 0.3377887882574666 0.2790588060601705 0.7801996957735544 1.0 1.0 6 Q9BQC3 1 +Regulation of glucose transmembrane transport 0.2875663437884006 0.2772804814025401 0.7815647457871351 1.0 1.0 13 P31751 1 +Cardioblast differentiation 0.4753657808301053 0.2768816624760075 0.7818709735587346 1.0 1.0 3 Q9H2U1,Q92908 2 +Anatomical structure maturation 0.2887347227022655 0.2768018185802935 0.7819322846890262 1.0 1.0 32 P11413,P21359,Q15645,O14965,Q08J23,Q8NHU6,Q15058,Q5TAX3,P18074,O75179 10 +Regulation of protein catabolic process 0.2700314961159042 0.2767357391023732 0.7819830273196084 1.0 1.0 124 O00560,Q05639,P62191,P15311,P43686,Q9P0J0,Q92990,Q7Z6Z7,P53350,O60826,Q96KB5,P78559,O96017,Q06787,O00487,P62081,Q96QK1,O14980,O43242,Q04323,P46379,P48506,P45974,P61289,P08238,O75832,P35241,Q9Y5A7,P40818,P19784,O43847,Q9ULT8,Q13526,Q13464,Q8IXJ6,O14965,P61086,Q9UL15,Q05086,O60493,O95376,Q9Y5K5,P14735,O95352,Q9NRR5,Q04206,O94966,O75150,P07900,Q9BW61,A4D1P6,P17612,P62195,Q13200 54 +Mononuclear cell differentiation 0.2445572811102686 0.2760482466758371 0.7825110098389403 1.0 1.0 48 Q6IBW4,Q9Y3I1,P00813,Q9ULT8,P00491,Q9Y4B6,O15347,Q00534,O00625,P09429,P49327,P62753,Q15648,P40763,P24390 15 +Regulation of protein dephosphorylation 0.291973629606766 0.2753490668827715 0.783048070836581 1.0 1.0 29 P31946,Q15257,Q69YH5,P42858,P67870,O75116 6 +Positive regulation of telomerase rna localization to cajal body 0.2869744865207579 0.275230136423454 0.7831394351913892 1.0 1.0 13 P49368,P50991,P40227,Q96HR8,P17987,P48643 6 +Smooth muscle cell migration 0.2954004317681986 0.2748642446589326 0.783420538072704 1.0 1.0 9 Q96N67 1 +Response to peptide 0.2391358729052313 0.2743901198135178 0.7837848349994949 1.0 1.0 93 P49770,P62993,Q00535,Q9UQB8,P41240,Q16539,Q14232,O75116,O60343,P14618,P09960,P11802,P07814,P48506,Q92974,P40763,O00443,Q96EB6,Q13464,O15357,P31751,Q13144,P20248,P07741,Q8TBX8,Q06124,P14735,P43490,Q99741,Q9NR50,O75150,Q9Y5X3,O14654,P27695 34 +Uronic acid metabolic process 0.6749253731343325 0.2743626856294995 0.7838059156855794 1.0 1.0 2 Q9NUJ1 1 +Folic acid containing compound metabolic process 0.289195830712244 0.2731931620920331 0.7847047359900992 1.0 1.0 15 P41440,P00374,Q8IYS1,P31939,Q9NRN7 5 +Biological process involved in intraspecies interaction between organisms 0.3578239654409723 0.2729692309516107 0.7848768678088271 1.0 1.0 5 Q9HCK8,Q9UIS9 2 +Cell cycle checkpoint signaling 0.2072116441939888 0.2724666070332939 0.7852632640285981 1.0 1.0 63 P33981,P53350,Q16539,Q92547,O96017,P50748,Q9Y6G9,Q9NXR7,Q13619,O60566,O43684,O60921,Q96RU2,O43683,Q9H900,Q6Y7W6,Q15645,Q08J23,P43246,Q06124,Q13564,Q13535,O43264,Q969U7,P14635 25 +Negative regulation of hydrolase activity 0.2126069156681394 0.272350797548219 0.7853523010155554 1.0 1.0 68 Q9C0C9,Q15392,O00170,P61221,Q96K76,Q9NR09,Q9P258,Q15257,Q04323,P36404,Q9GZT9,P61201,O75116,P30086 14 +Copii coated vesicle cargo loading 0.2945466035267427 0.2720534554247961 0.7855809173153869 1.0 1.0 9 Q9NR31,P53992,Q15436,O94979,O95487 5 +Positive regulation of cellular component biogenesis 0.2651036907448214 0.270044952764823 0.7871256705135057 1.0 1.0 120 O00560,P62993,P41440,Q8NCA5,Q9Y295,Q9UQB8,P62333,Q7Z460,P60953,Q9H6U6,Q15555,Q6IBS0,O75116,Q16512,Q06787,Q7L576,O00401,Q14008,Q99996,Q9HCM4,Q9NZN8,P49427,P26358,Q86VP6,Q96AC1,Q13464,Q14203,Q13283,Q8TBX8,Q04637,Q13535,Q15691,P35080,P50570,Q13153,P36404,P07900,P42858,O75351,Q15042,P23381,Q14204,P07737,Q9Y613,P62195,Q9BPX3,A5YKK6,P27695 48 +Leukocyte differentiation 0.2121953534089291 0.2695698412149155 0.7874912048582607 1.0 1.0 68 Q9Y3I1,P00813,Q16539,Q13619,O00625,P09429,Q15648,P40763,Q96EB6,P21359,Q9ULT8,Q14790,Q9Y4B6,P49327,P62753,P24390,Q6IBW4,P00491,P43034,O15347,O00203,Q00534 22 +Protein k63 linked deubiquitination 0.2853207851704782 0.2695533370389639 0.7875039034405826 1.0 1.0 13 O95630,Q01804,P40818 3 +Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.3791199762479121 0.269214168695298 0.7877648776043071 1.0 1.0 4 P78417 1 +Cellular response to nitrogen compound 0.2835084520813913 0.2687683596366237 0.7881079430491857 1.0 1.0 140 P62993,P55210,P41440,Q9P2J5,Q00535,Q9UQB8,P27695,P17655,Q9NUD5,P41240,Q9UER7,Q6L8Q7,O75116,Q06787,Q99996,Q96QK1,O60343,P14618,Q9BY42,P11802,P07814,P48506,P26358,Q8IWV7,Q92974,P40763,O00443,Q96EB6,Q6PKG0,Q13464,Q8IXJ6,Q99707,P31751,P55212,P20248,P07741,Q8TBX8,Q8IZH2,Q06124,P14735,P28482,P43490,P17612,Q99741,Q04206,P50570,O60610,Q9Y5X3,P46109,O14744,O14654,P42574,P28161,P15311,P48507 55 +Detection of abiotic stimulus 0.3068486713879034 0.2674397895792595 0.7891305670775344 1.0 1.0 8 Q13432,Q15555 2 +Positive regulation of telomerase activity 0.2872043083136709 0.2663241559370454 0.7899895709387255 1.0 1.0 15 P07900,Q9BUR4,P08238,Q96HR8,P28482,P17987,P13010 7 +Learning 0.2914491402315564 0.2657816312484567 0.7904073907049103 1.0 1.0 20 P21359,Q05086,Q9NPQ8,P42858 4 +Receptor internalization 0.2919704111719553 0.2652291650610434 0.7908329287299545 1.0 1.0 22 P62993,P41440,P50570,Q15334,Q00610,Q9UL63,Q06787,P15311,Q13614,P49407 10 +Regulation of adaptive immune response 0.2920066701539613 0.2651756858867315 0.7908741244676465 1.0 1.0 24 P00813,O43318,P09429,Q96FZ2,Q16512 5 +10 formyltetrahydrofolate metabolic process 0.4702762527888213 0.2650527431643901 0.7909688311393164 1.0 1.0 3 Q9NRN7 1 +Tumor necrosis factor superfamily cytokine production 0.2911197528372869 0.2646185029271331 0.7913033648351595 1.0 1.0 20 P30046,Q9Y6D5,P09429,P40763 4 +Roof of mouth development 0.3058603084350813 0.264332017405799 0.7915240910443582 1.0 1.0 8 Q6W2J9 1 +Vesicle targeting rough er to cis golgi 0.2802934397284654 0.2642018817342638 0.7916243611568907 1.0 1.0 11 O00743,Q92734,O15027,Q9Y6B6,Q13618 5 +Golgi to plasma membrane protein transport 0.2860100492062265 0.262260041597234 0.7931209662612426 1.0 1.0 15 Q4J6C6,Q9UJY4 2 +Connective tissue development 0.2905777851733416 0.2620186157104067 0.7933070901778914 1.0 1.0 26 Q96EB6,Q8N0X7,P20248,A1X283,P43490 5 +Response to fibroblast growth factor 0.2774322052863778 0.2611866257289927 0.7939485913775146 1.0 1.0 10 P48506,P46109,Q06124 3 +Ether metabolic process 0.3047829220397082 0.2609696522786138 0.7941159104738538 1.0 1.0 8 P07099,P49327 2 +Protein containing complex disassembly 0.234875649411632 0.2604323443038774 0.7945302963346881 1.0 1.0 91 P47756,P61221,Q7Z460,Q99570,Q6IBS0,P78559,P47755,O15020,Q14008,P35611,O15344,P62495,P33176,P16949,P35241,P29372,Q92974,P60981,Q99661,Q01105,Q66K74,Q9Y4P8,P63241,Q9UEY8,Q9Y5B9,Q9H269,Q9NRR5,Q15058,O75351,P54920,Q9BPX3 31 +Cerebellar cortex development 0.283968403024502 0.2599314858475156 0.7949166236054979 1.0 1.0 14 O15020,Q00535,Q15058,Q06124 4 +Microtubule bundle formation 0.2838856669638884 0.2596547243415391 0.7951301197046861 1.0 1.0 14 O43663,Q66K74,P53350,Q7Z460,Q15555,Q86Y56,Q15691,Q9UHD1,P46821 9 +Regulation of heart growth 0.2768317257793249 0.2592136432304549 0.7954704050021124 1.0 1.0 10 P11413,Q99956,Q16539 3 +Respiratory system development 0.2898406073138513 0.2580195595564495 0.7963918118540254 1.0 1.0 25 P00813,P09960,O60568,P46379,O00203,P28482,O95487 7 +Negative regulation of guanyl nucleotide exchange factor activity 0.4668383616872265 0.2572400771259508 0.7969934476131262 1.0 1.0 3 P16949 1 +Phospholipid dephosphorylation 0.3304887232102588 0.2571628272321115 0.7970530787515939 1.0 1.0 6 Q13614,O15357 2 +Phosphatidylinositol dephosphorylation 0.3304887232102588 0.2571628272321115 0.7970530787515939 1.0 1.0 6 Q13614,O15357 2 +Positive regulation of interleukin 10 production 0.4667730589420947 0.2570930729640858 0.79710692484553 1.0 1.0 3 P09429 1 +Mitotic cell cycle checkpoint signaling 0.2408931762237426 0.256467999638511 0.7975894868764519 1.0 1.0 48 P33981,P53350,P61254,Q92547,O96017,P50748,Q9Y6G9,Q9NXR7,O60566,O43684,O60921,O43683,Q9H900,Q6Y7W6,Q15645,P43246,Q13564,Q99741,O43264,Q969U7,P14635 21 +Pallium development 0.2721819667281216 0.2550553323283078 0.7986803630272972 1.0 1.0 38 P21359,Q00535,P43034,O43776,Q13144,Q15058,Q96P11,A0AVT1,Q00534,P42574,P31939,P19784 12 +Morphogenesis of an epithelium 0.2089277572629971 0.2550370621290943 0.7986944740414801 1.0 1.0 67 P62993,Q9Y696,Q92990,Q7Z460,P60953,Q96Q89,Q92796,Q16512,P62081,Q9HCM4,P25440,P67870,Q96AC1,Q15648,Q9ULT8,Q13043,O00330,P20248,O95487,P11586,Q13153,P43034,P42574,O60568,P17612,P07737,P15311 27 +Heart development 0.2369532701251737 0.2545163389586527 0.7990966829437529 1.0 1.0 94 P11310,P55210,P21359,P11413,Q9ULT8,Q14790,P42574,Q6W2J9,P13807,P28482,Q99956,Q9BQ70,P20248,A1X283,Q06124,O75116,Q15648,Q99873 18 +Positive regulation of protein dephosphorylation 0.2807710788862186 0.2543348347121289 0.7992368901687408 1.0 1.0 13 Q8IV63,Q15257,Q69YH5,Q14738,P08238 5 +Telencephalon development 0.2581529068142649 0.2536754069813252 0.7997463350750973 1.0 1.0 43 P21359,Q00535,P43034,P00492,O43776,Q13144,Q15058,Q96P11,A0AVT1,Q00534,P42574,P31939,P19784 13 +Protein localization to mitochondrion 0.2032408724414597 0.253049348786229 0.8002300790140655 1.0 1.0 62 O00170,Q9P0J0,P68036,O00429,Q15785,O60830,P55786,O14737,P31689 9 +Lymphocyte activation involved in immune response 0.286042303656084 0.2525510043303701 0.8006151956309386 1.0 1.0 29 P00813,P09429,P52701,Q96FZ2,Q9UQ84,P40763 6 +Endocrine process 0.3500174027829582 0.2510065370843848 0.8018090550945258 1.0 1.0 5 Q06124 1 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.3283714123002813 0.2510028081785497 0.8018119380668627 1.0 1.0 6 P78417 1 +Epithelial cell morphogenesis 0.3148509418068612 0.2505400185430613 0.8021697609370528 1.0 1.0 7 Q9Y696,O60568,Q13464 3 +Response to mechanical stimulus 0.2873111845199473 0.2489569539298119 0.8033940789848228 1.0 1.0 25 Q04206,Q14790,Q99439,P45985,Q16539,P42858,P48506,Q9UKL3,P49327,P06744 10 +Positive regulation of transferase activity 0.2527302879599833 0.2484033688022048 0.8038223273257488 1.0 1.0 111 Q05639,Q00535,P49643,P53350,P60953,Q9BUR4,P52564,P41240,Q99570,Q9UER7,Q9UNI6,Q96HR8,Q92796,Q16512,Q9Y376,P68036,P36507,O43318,P08238,O75832,Q96AC1,Q99627,Q96EB6,Q13526,Q13043,Q15334,Q13432,P20248,Q08AM6,P28482,Q92616,P17987,Q14012,P15880,Q99741,Q13153,P07900,Q9H8V3,Q15058,O75909,Q96JP5,P13010,P14635,Q9BRT9,Q16763 45 +Positive regulation of extrinsic apoptotic signaling pathway 0.2771761476265361 0.2480827224657661 0.8040704033127892 1.0 1.0 12 P21359,Q9UNN5,Q13043,Q13177,P30154,P30153,Q13546 7 +Regulation of endothelial cell migration 0.2846566595585246 0.2474135814558099 0.8045881643778983 1.0 1.0 29 Q96EB6,Q8WTV0,P21359,P09429,P67870,O75116 6 +Positive regulation of b cell activation 0.2784921560422014 0.2469349865765917 0.8049585392094059 1.0 1.0 13 P00813 1 +Modification dependent macromolecule catabolic process 0.3275477730958132 0.2463956318727535 0.8053759872908255 1.0 1.0 198 Q15369,Q7Z6Z7,Q96S82,P51784,P25787,O00487,Q14999,P49427,Q96RU2,Q13617,Q9UPT9,Q9Y263,P61086,Q05086,O95376,Q5VYK3,O94822,Q93008,Q8N3C0,Q9Y3I1,Q5TAX3,P22314,P22681,Q9UHG3,P55036,P48506,P45974,Q15386,P40818,Q9UL15,Q9UJX4,Q16186,O95628,O94966,A0AVT1,P62195,Q16763,P62191,Q5T4S7,Q7L5D6,Q96K76,Q92990,Q93034,Q14694,Q14258,O60826,Q96KB5,P78559,Q13619,O14980,P68036,O43242,O95260,Q04323,P19784,Q96EB6,P49407,Q8IXJ6,Q13618,Q6GQQ9,Q9Y5K5,Q86UV5,Q9NRR5,O75150,O75351,A4D1P6,Q5VTR2,Q13501,P43686,Q15008,Q13309,P62081,P46379,Q8IWV7,Q9Y5A7,Q9ULT8,O14965,Q8IUR7,Q8TAT6,Q9Y5K6,Q15058,Q13200 82 +Nuclear transcribed mrna catabolic process 0.2011006576173459 0.2461379730739815 0.805575428838651 1.0 1.0 61 Q92900,Q5TAX3,Q6PGP7,Q96F86,P62495,Q969T7,Q86TB9,Q9UPR3,Q9HAU5,Q6P2E9,Q5PRF9,P05455,Q9UIV1,O75534,Q9Y2L1,Q96C86,Q15477,P67809,A5YKK6 19 +Microtubule based movement 0.2221926548127589 0.2456556390252498 0.8059488149143366 1.0 1.0 81 Q9UBF2,Q96Q89,P78318,P78559,O60333,Q9Y6G9,P57076,P33176,O14617,Q99661,Q9BW83,Q66K74,Q9Y2T2,Q14203,Q00796,Q86Y56,O43237,Q9UIS9,Q9NZ32,P43034,Q03001,Q14204,O00203,Q15058,P42858,Q8TD16,P63172,Q15398,O95239,P52732,P27695 31 +Positive regulation of leukocyte chemotaxis 0.2762913411143478 0.2452550060172736 0.8062589879432576 1.0 1.0 12 P09429,O00429 2 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.2857129771590806 0.2444257176521799 0.8069011258962091 1.0 1.0 26 P53621,P48444,Q92538,P61923,Q96JB2,P48739,P42858,Q8TD16,Q9UBF2,Q96RQ1,P35606,P24390 12 +Endosome transport via multivesicular body sorting pathway 0.3260609683203772 0.2443804434903184 0.8069361865212052 1.0 1.0 6 P55072,Q8WUX9,O75351,Q92783,Q9NZZ3 5 +Multivesicular body sorting pathway 0.3260609683203772 0.2443804434903184 0.8069361865212052 1.0 1.0 6 P55072,Q8WUX9,O75351,Q92783,Q9NZZ3 5 +Escrt complex disassembly 0.3260609683203768 0.2443804434903172 0.8069361865212061 1.0 1.0 6 P53990,Q8WUX9,O75351,Q9UN37,Q9NZZ3 5 +Negative regulation of viral transcription 0.3695352903231459 0.243879239195339 0.8073243485064223 1.0 1.0 4 P19474,Q9NZI7 2 +Positive regulation of exosomal secretion 0.3124810096278966 0.2435966984288795 0.8075431855570343 1.0 1.0 7 O00560,Q8WUM4,Q99816,O75351,Q9UN37 5 +Regulation of exosomal secretion 0.3124810096278966 0.2435966984288795 0.8075431855570343 1.0 1.0 7 O00560,Q8WUM4,Q99816,O75351,Q9UN37 5 +Endocytic recycling 0.2848968458175032 0.2432831284991457 0.8077860733414899 1.0 1.0 20 Q9UID3,O60826,Q9H4M9 3 +Regulation of t circle formation 0.6588059701492586 0.2427241618411365 0.8082190886469753 1.0 1.0 2 P13010 1 +Regulation of animal organ morphogenesis 0.298444976076554 0.2417313209275622 0.8089883585696331 1.0 1.0 8 P35222,P61586,P60953,P63000,Q9Y5V3,O95487,Q13308 7 +Neural tube formation 0.2846738816564161 0.2409681721203001 0.8095797847150921 1.0 1.0 21 P11586,P62081,Q9ULT8,Q13043,Q92990,P25440,Q96Q89,P42574,P07737,O95487 10 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.3682451459431387 0.2405852253230138 0.8098766023722594 1.0 1.0 4 Q96IU4,O95861 2 +Response to glucagon 0.6573134328358267 0.2399177860132021 0.8103939922476868 1.0 1.0 2 P20248 1 +Tor signaling 0.2842413850001025 0.2377928137295542 0.8120417926385577 1.0 1.0 24 Q96EB6,Q96B36,Q6PKG0,Q15382,Q8IWV7 5 +Positive regulation of cell cycle phase transition 0.236708515679614 0.2352543963488548 0.8140112882878694 1.0 1.0 48 Q96DY7,Q13619,Q9P258,P27695,Q13618,P11802,Q9UJX4,P35241,P30307,Q15398,Q04637,Q7L2J0,O96017,P14635,P31350,P23921,O75179 17 +Nadp metabolic process 0.2777343743935112 0.2352489830646264 0.8140154895834257 1.0 1.0 15 P11413,O75874,P48735,P18669,O95336 5 +Epithelial cell proliferation 0.2537950775389975 0.2339573582072507 0.8150180832040179 1.0 1.0 43 Q96EB6,Q8WTV0,P21359,P19174,P15531,P28482,Q00534,P09429,Q15648,P40763 10 +Regulation of synapse structure or activity 0.2776077583737583 0.2334532666621114 0.815409454783387 1.0 1.0 32 Q00535,Q96QK1,Q9UQB8,P63104,P61160,P43034,P60953,Q16539,P07437,Q14203,Q05086,Q04637,Q7L576,Q14012 14 +Neutral lipid biosynthetic process 0.3088982918976227 0.2333289701276033 0.8155059644386364 1.0 1.0 7 Q8WTV0 1 +B cell activation involved in immune response 0.2792460943910334 0.2326191690103761 0.816057140882765 1.0 1.0 17 Q9UQ84,P00813 2 +Positive regulation of chemokine c x c motif ligand 2 production 0.6531343283582154 0.2321722891931953 0.8164041997615772 1.0 1.0 2 P09429 1 +Chemokine c x c motif ligand 2 production 0.6531343283582154 0.2321722891931953 0.8164041997615772 1.0 1.0 2 P09429 1 +Regulation of icosanoid secretion 0.6531343283582138 0.2321722891931924 0.8164041997615794 1.0 1.0 2 P52564 1 +Regulation of prostaglandin secretion 0.6531343283582138 0.2321722891931924 0.8164041997615794 1.0 1.0 2 P52564 1 +Negative regulation of canonical wnt signaling pathway 0.2789996202582742 0.2318423393598142 0.81666047078481 1.0 1.0 17 Q9HCK8,Q16539,Q13283,Q99471,Q04727 5 +Positive regulation of transmembrane transport 0.2741494257536551 0.2313937464801141 0.8170089229390474 1.0 1.0 34 P11413,Q99996,P19174,P31751,P42858,Q06124,P78417,P28161,P35754,P27695 10 +Cell cycle phase transition 0.2954883240994922 0.2306818074190786 0.8175620079516175 1.0 1.0 162 Q9Y3I1,Q00535,Q96K76,P33981,P53350,Q7Z460,Q93034,Q16539,O95067,P42771,Q92900,P18074,Q92547,Q7L2J0,P50748,Q96DY7,O96017,P31350,P23921,Q13309,O00743,Q9Y6G9,Q13619,O60566,Q9NXR7,P68036,O43684,P49427,P11802,O95905,O60921,P61289,Q96RU2,Q96BK5,Q13617,P35241,Q08209,O43683,Q9H900,Q6Y7W6,Q9P258,Q15645,P83731,Q8IXJ6,O14965,Q9Y570,Q08J23,Q13618,P43246,Q9UJX4,P20248,P30307,Q06124,Q04637,Q13564,P62753,Q13535,Q7Z7L1,Q99741,P50570,P06730,Q07864,Q15058,Q00534,O75351,O43264,O75179,Q969U7,Q15398,P14635,Q16763,P27695 72 +Receptor catabolic process 0.294536197711425 0.2303350494223654 0.8178314271959983 1.0 1.0 8 Q13614,Q00535 2 +Brainstem development 0.651940298507469 0.2299898005957677 0.8180996952454791 1.0 1.0 2 P31939 1 +Cysteine metabolic process 0.3207709910274899 0.2296143363100164 0.818391465736032 1.0 1.0 6 P48506,P32929,P48507 3 +Positive regulation of cell development 0.1994271961792394 0.2287981426871939 0.8190258104253045 1.0 1.0 62 Q15382,Q14999,Q9UQB8 3 +Regulation of protein neddylation 0.4535682293221917 0.2284537602538267 0.8192934995954717 1.0 1.0 3 P62913,P46777 2 +Positive regulation of endocytosis 0.2793172499188513 0.2272891929090907 0.8201988760309071 1.0 1.0 19 P41440,Q08209,P22681 3 +Myelin assembly 0.3194565846440665 0.2260319437986356 0.8211765756117302 1.0 1.0 6 P18074,Q13614 2 +Ribonucleoprotein complex disassembly 0.3406035255452577 0.2259778907326312 0.8212186162111295 1.0 1.0 5 Q07866,Q9UBB9,P33176,P55072 4 +Microvillus organization 0.2928589701693883 0.2255561901239962 0.8215466179356621 1.0 1.0 8 Q6IBS0,P15311,Q16658,Q06124 4 +Male gamete generation 0.2114669497178619 0.2250217997587057 0.8219623153654878 1.0 1.0 74 Q96EB6,Q9BW83,P50570,Q15645,Q6P6C2,Q14997,P46379,Q8NHU6,Q08J23,Q96PU8,P30307,P52701,Q9H6S0,O95394,Q14353,Q96SB4,P19784 17 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.2133381840766696 0.2248032762658435 0.8221323172203874 1.0 1.0 53 O00560,O75925,P53350,Q92990,Q96KB5,P78559,O14980,Q04323,P46379,P48506,P45974,P08238,O75832,O43765,Q9Y5A7,Q9ULT8,O14965,Q8IXJ6,P61086,Q9UL15,O95376,Q9Y5K5,Q9NRR5,Q9Y4X5,Q9BW61 25 +Negative regulation of erbb signaling pathway 0.3056662986532116 0.2243053240360807 0.822519733769681 1.0 1.0 7 P22681 1 +Hydrogen sulfide metabolic process 0.6486567164179154 0.2240581401275751 0.8227120637508698 1.0 1.0 2 P32929 1 +Hydrogen sulfide biosynthetic process 0.6486567164179154 0.2240581401275751 0.8227120637508698 1.0 1.0 2 P32929 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.2693842682546289 0.2239604680523057 0.8227880638207543 1.0 1.0 12 Q9UIV1,O75534,P67809 3 +Negative regulation of dna metabolic process 0.23808845070398 0.2238047244799635 0.8229092536103328 1.0 1.0 47 Q03164 1 +Peptidyl serine autophosphorylation 0.4509952409453873 0.223128160122431 0.8234357621651931 1.0 1.0 3 P36507 1 +Regulation of vascular permeability 0.304633781763839 0.2214707599247944 0.8247259015235444 1.0 1.0 7 Q9UDY2,Q07157,Q15149,Q02952,Q96AC1,P07947 6 +Blood vessel morphogenesis 0.2210243643212288 0.2207924867470543 0.8252540139318238 1.0 1.0 84 Q9Y696,Q92990,Q9BXJ9,O75116,Q14999,P14618,P19174,Q96PU8,Q96AY3,Q15648,Q96TA1,P40763,P78362,P21359,Q96EB6,Q14790,P20248,O95487,Q96BN8,Q9GZT9 20 +3 utr mediated mrna destabilization 0.3170950388523517 0.2196830624038338 0.8261179966875496 1.0 1.0 6 Q9H2U1,Q92945,Q92900,Q13148,Q9HCE1 5 +Cellular protein catabolic process 0.3529015659849682 0.2195507553792247 0.8262210470700475 1.0 1.0 243 Q16740,Q15369,P17655,Q7Z6Z7,Q96S82,P51784,P25787,O00487,Q14999,P28066,P49427,Q96RU2,Q13617,P28070,Q9UPT9,Q9Y263,P61086,Q05086,O95376,P14735,Q5VYK3,O94822,Q93008,Q8N3C0,Q9Y3I1,P25786,P22314,P20618,O96017,P22681,Q9UHG3,Q14997,P55036,P48506,P45974,Q15386,P40818,Q14790,Q9UL15,Q9UJX4,Q16186,O95628,O94966,A0AVT1,P62195,Q16763,P62191,Q5T4S7,Q7L5D6,Q96K76,Q92990,Q93034,Q14694,Q14258,O60826,Q96KB5,P78559,Q06787,Q13619,O14818,O14980,P68036,O43242,O95260,Q04323,P61289,P35241,P49721,P19784,Q96EB6,P49407,Q8IXJ6,Q13618,Q6GQQ9,Q9Y5K5,Q86UV5,Q9NRR5,O75150,P07900,Q9Y5X3,O75351,A4D1P6,P28074,Q5VTR2,Q13501,P15311,P43686,P60900,P53350,Q15008,Q13309,P62081,P46379,P49720,Q8IWV7,Q9Y5A7,Q9ULT8,O14965,Q8IUR7,Q8TAT6,Q9Y5K6,Q15058,Q13200 103 +Protein localization to cell junction 0.2773241055391755 0.2189838096667066 0.8266626597101792 1.0 1.0 20 Q96AC1,P78559,Q9UQB8 3 +Negative regulation of wnt signaling pathway 0.2778325087644218 0.2189146503276378 0.8267165339462532 1.0 1.0 21 Q9HCK8,Q96C57,Q16539,Q13283,Q99471,Q04727 6 +Ectoderm development 0.4488164044955376 0.2186841874423042 0.8268960674576986 1.0 1.0 3 P13693 1 +Regulation of cell cycle phase transition 0.2585380848935508 0.2185484924217537 0.827001779833074 1.0 1.0 123 Q9Y3I1,Q96K76,P33981,P53350,Q16539,P42771,P18074,Q92547,Q7L2J0,Q96DY7,O96017,P50748,P31350,P23921,Q9Y6G9,Q13619,O60566,Q9NXR7,O43684,P11802,O95905,O60921,P61289,Q96BK5,Q96RU2,P35241,O43683,Q9H900,Q6Y7W6,Q9P258,Q15645,Q8IXJ6,O14965,Q13618,Q08J23,P43246,Q9UJX4,P30307,Q06124,Q04637,Q13564,Q13535,Q7Z7L1,Q99741,Q15058,O75351,O43264,O75179,Q969U7,Q15398,P14635,P27695 52 +Folic acid metabolic process 0.2903505766458915 0.2185348223054472 0.8270124296273824 1.0 1.0 8 P00374,P41440 2 +Glutathione metabolic process 0.2774372099045016 0.2176873329843746 0.8276727338263934 1.0 1.0 21 O00299,P11413,O75874,Q8WUX2,P48506,P78417,P28161,P26641 8 +Positive regulation of cell junction assembly 0.2633639937658953 0.2176396557895805 0.8277098841742943 1.0 1.0 10 Q96AC1,P41440,Q13464 3 +Regulation of leukocyte differentiation 0.2757648920959739 0.2161774438935503 0.8288494350197027 1.0 1.0 29 P21359,Q9Y3I1,P00813,P00491,Q14790,O15347,O00203,Q00534,P09429 9 +Protein localization to nucleoplasm 0.2683259802412173 0.2157749347391382 0.8291631872579337 1.0 1.0 13 P49368,Q99832,Q4G0J3,P50991,Q9BUR4,P40227,Q7L2J0,P17987,P48643 9 +Cell recognition 0.2772967173003853 0.2150490744457796 0.8297290576278051 1.0 1.0 24 Q8WTV0,P04075,P63104,Q92614,Q14157,P42574,P17987,P48643 8 +Skeletal muscle organ development 0.2770060657209694 0.2150345046036881 0.8297404169749723 1.0 1.0 26 P21359,P41440,Q00535,O94966,P51114,P61201,Q96TA1,Q08209 8 +Regulation of protein complex stability 0.3359885822267417 0.2143046268727693 0.8303095101330469 1.0 1.0 5 Q13501 1 +Anterograde axonal transport 0.2707204662179336 0.2139616712772094 0.8305769468910458 1.0 1.0 15 O95239,Q9Y2T2,O60333,O00203,P33176,P78559,O14617,P27695 8 +Regulation of cell size 0.2490872786557517 0.2138868988387733 0.8306352570420108 1.0 1.0 43 Q96B36,Q9P2J5,Q00535,Q8N0X7,P50570,P43034,Q9Y666,Q6IBS0,P35241,P08238,Q9P265,Q96ER9,P15311 13 +Peptidyl diphthamide biosynthetic process from peptidyl histidine 0.642686567164185 0.213538072975652 0.830907295913873 1.0 1.0 2 Q9BQC3 1 +Regulation of b cell activation 0.2754945752347901 0.2133913334478983 0.8310217397457988 1.0 1.0 20 P42574,Q96FZ2,Q16512,P00813 4 +Regulation of epithelial cell migration 0.2489323999019066 0.2132485142087866 0.8311331295412023 1.0 1.0 43 Q96EB6,Q8WTV0,P21359,P19174,Q15555,Q14185,P09429,P67870,P35080,O75116 10 +Microtubule cytoskeleton organization 0.3043983798229576 0.211571930290285 0.8324410099597181 1.0 1.0 178 P68371,Q9BV86,Q9Y295,Q00535,P15311,P33981,Q7Z460,Q9HBM1,Q9H6U6,Q15555,O95067,Q15813,Q9BT25,Q9BUF5,O75116,P78559,Q16512,O96017,Q14999,Q14008,Q99996,Q96N67,Q9UH99,O14980,O15344,Q96S59,Q96CW5,P16949,Q9BTW9,P29372,Q92974,Q8TEW0,Q99661,Q96EB6,P35579,Q66K74,Q15257,Q7Z4H7,O14965,P04350,Q9BSJ2,Q15334,Q14203,P07437,Q14155,Q96P70,O43237,Q9UIS9,Q9HC35,Q15691,Q13153,P43034,P36404,P43487,Q03001,Q15058,P42858,P63172,O75351,Q8TD16,O43264,Q13885,Q14204,Q15398,P14635,Q8NI35,P52732 67 +Regulation of muscle system process 0.2633355595502054 0.2113418249066657 0.8326205483454836 1.0 1.0 37 P00813,Q99996,O75116,Q86TU7,Q08209 5 +Peptidyl tyrosine modification 0.2611092066856142 0.2107948771144588 0.8330473362013282 1.0 1.0 38 P49761,P45985,P41240,P36507,Q15334,P22059,Q9UIV1,Q13432,Q96KB5,Q92796,Q92974,Q06124,P22681 13 +Positive regulation of cell cycle process 0.2170704640022161 0.2101996909589903 0.8335118207544743 1.0 1.0 82 Q96Q89,O75116,Q7L2J0,O96017,Q96DY7,P31350,Q96DE0,P23921,Q13619,P11802,P39748,P35241,Q15648,Q9P258,Q8IXJ6,O14965,Q13618,Q9UJX4,P30307,Q04637,Q16513,O94966,P43487,Q9H8V3,Q15058,O75351,O75179,Q14204,Q15398,P14635,P27695 31 +Regulation of protein kinase activity 0.2482340176440166 0.2091450661203085 0.8343349948610363 1.0 1.0 114 O00410,Q9Y3I1,Q00535,Q13177,P53350,P14174,P41240,P52564,O95067,P42771,P46940,Q9UER7,Q92796,Q16512,Q53EL6,P22681,Q9Y376,P36507,P47897,O43318,P08238,O75832,P51452,Q96AC1,P31689,Q99627,Q96EB6,P21359,Q9UII4,P49736,Q13043,Q15334,Q13432,P20248,P30307,Q16543,Q14012,Q96B36,Q99741,O95373,Q13153,P07900,Q9Y4R8,Q9H8V3,Q9NYV4,Q15058,Q9P287,P42858,O75909,P23381,Q96JP5,P42574,P13010,P14635 54 +Tetrahydrofolate metabolic process 0.2623738890394219 0.209050864879122 0.8344085312980445 1.0 1.0 11 P00374,P31939,Q9NRN7 3 +Lysosomal transport 0.2662066645078146 0.2084585104235737 0.834870974883331 1.0 1.0 35 Q9H269,P20645,Q7Z3T8 3 +Endosomal vesicle fusion 0.6397014925373186 0.2084066737659723 0.8349114458218541 1.0 1.0 2 Q9P2R3 1 +Positive regulation of epithelial to mesenchymal transition 0.2995515695067384 0.2078620292446336 0.83533669785351 1.0 1.0 7 O00560,P35222,Q92769,Q9H7S9,P42345,Q96AC1 6 +Nadh metabolic process 0.2728292752722711 0.2075388480695117 0.8355890566793418 1.0 1.0 19 P85037,P17858 2 +Proteasomal protein catabolic process 0.2904699655451327 0.207487568047816 0.8356291006860543 1.0 1.0 162 O00560,P62191,Q7L5D6,P43686,P62333,Q92990,P60900,Q7Z6Z7,Q93034,P53350,P25789,Q15008,Q14258,Q96KB5,P25786,P20618,P25787,P78559,Q86UK7,O00487,Q06787,Q13309,Q13616,Q13200,Q13619,O14818,O14980,P28066,P49427,Q14997,P55036,P48506,Q04323,P45974,O95260,P61289,P46379,P49720,P08238,O75832,Q8IWV7,Q13617,Q9Y5A7,P28070,P49721,P49407,Q96EB6,Q9ULT8,Q9Y263,Q8IXJ6,O14965,Q13618,P61086,Q9UL15,Q9UJX4,O95376,Q9Y5K5,Q8IUR7,Q8TAT6,Q9NRR5,O94966,O75150,Q9UJX5,Q9BW61,Q9Y5K6,Q5VYK3,Q15058,O94822,P28074,Q8N3C0,P17612,P62195,Q16763 73 +Regulation of receptor clustering 0.3543883467930906 0.2069894966319851 0.8360180613450612 1.0 1.0 4 P46109 1 +Negative regulation of interleukin 8 production 0.3542475455512289 0.206665098296156 0.8362714164470697 1.0 1.0 4 P49407 1 +Response to type i interferon 0.2693786904200889 0.2063159413877043 0.8365441269737195 1.0 1.0 16 Q14166,Q9UHD2,Q9Y3Z3,P61086,Q9UIV1,Q06124 6 +Negative regulation of cell cycle g1 s phase transition 0.2649364479996916 0.2060679309430758 0.8367378485488268 1.0 1.0 13 Q9Y3I1,Q7Z7L1,O96017 3 +Positive regulation of telomere maintenance via telomere lengthening 0.2730147339824056 0.205985240958124 0.8368024401031218 1.0 1.0 20 P49368,P50991,P40227,Q96HR8,P28482,P17987,P13010,P48643,Q13535 9 +Negative regulation of cell cycle phase transition 0.2069855696726183 0.2055026074863435 0.8371794610940906 1.0 1.0 73 Q9Y3I1,Q96K76,P33981,P53350,Q16539,Q92547,O96017,P50748,Q9Y6G9,Q9NXR7,Q13619,O60566,O43684,O60921,Q96BK5,Q96RU2,O43683,Q9H900,Q6Y7W6,Q15645,Q08J23,P43246,Q06124,Q13564,Q7Z7L1,Q13535,O43264,Q969U7,P14635 29 +Positive regulation of myeloid cell differentiation 0.2711930747185903 0.2052839782535112 0.8373502610011789 1.0 1.0 18 Q14790,Q16539,Q15648,Q99873,P40763 5 +Gdp metabolic process 0.3536439665471814 0.2052783978284139 0.8373546207019307 1.0 1.0 4 Q9UDY2,Q12959,Q00013 3 +Regulation of organ growth 0.2628557947865199 0.2051211854854814 0.8374774447175366 1.0 1.0 12 P11413,Q9UGN5,Q99956,Q16539 4 +Cellular response to ionizing radiation 0.273844514806564 0.2044647911597515 0.8379903033622178 1.0 1.0 25 Q96EB6,P62993,Q9NXR7,P50570,Q9H8V3,Q16539,O60921,P29692,P13010,O96017,Q13535 11 +Cardiac conduction system development 0.4410271722902468 0.2032942280002355 0.8389050667235485 1.0 1.0 3 P60953,Q92908 2 +Tyrosine metabolic process 0.4407840379236817 0.2028264084566801 0.839270715967144 1.0 1.0 3 P16930 1 +Spinal cord development 0.2619082012081881 0.2024918948662002 0.8395321941331935 1.0 1.0 12 P21359,P18074,Q6Y7W6 3 +Response to camp 0.2614569250265596 0.2012491544899834 0.8405037579273262 1.0 1.0 12 Q99996 1 +Regulation of extent of cell growth 0.2720179829166727 0.2001218507491137 0.8413852845928371 1.0 1.0 22 Q8N0X7,P50570,P43034,Q00535,Q9P265 5 +Positive regulation of dna binding 0.2682290383124758 0.1997410010458752 0.8416831456634 1.0 1.0 17 P15531,O00330,P18074,P09429,Q96BK5,Q96TA1 6 +Endothelial cell development 0.2712860971373437 0.1992564378196094 0.8420621534269672 1.0 1.0 21 Q9Y696,Q07157,P21266,Q13464,P35611,O60568,P35241,P49327,P55196,O75116,P15311,Q9Y4G8 12 +Plasma membrane organization 0.2711409664455544 0.1991635648247113 0.8421347994936743 1.0 1.0 28 P31751,Q9UQB8 2 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.2705000187169559 0.1991121758155026 0.8421749970024328 1.0 1.0 29 Q9Y2L1,P67809,Q96C86,Q5PRF9,Q5TAX3,Q9UIV1,O75534,Q969T7,Q86TB9,A5YKK6 10 +Response to antibiotic 0.2583990992959271 0.198085292438227 0.8429783317701376 1.0 1.0 11 Q14790,P22681 2 +Myofibroblast differentiation 0.6328358208955278 0.1969312364191353 0.843881349173506 1.0 1.0 2 Q53EL6 1 +Protein auto adp ribosylation 0.6328358208955277 0.1969312364191351 0.8438813491735062 1.0 1.0 2 Q9UGN5 1 +Central nervous system neuron axonogenesis 0.3081729308983677 0.1967240821418091 0.8440434635151153 1.0 1.0 6 P07900,P08238,P43034 3 +Regulation of nmda receptor activity 0.6325373134328413 0.196442658064906 0.8442637103371113 1.0 1.0 2 Q15334 1 +Regulation of dna damage response signal transduction by p53 class mediator 0.2596305348390077 0.1962817226574202 0.8443896663422181 1.0 1.0 12 Q13535 1 +Regulation of granulocyte chemotaxis 0.2687770761270952 0.1959956292662172 0.8446135869935909 1.0 1.0 9 O00429 1 +Regulation of rna polymerase ii transcription preinitiation complex assembly 0.3493035296868279 0.1954938647257388 0.8450063402628272 1.0 1.0 4 P09429 1 +Establishment of endothelial barrier 0.2666547787585229 0.1953535995698785 0.8451161388905211 1.0 1.0 17 Q07157,Q13464,P35611,P49327,P26038,P35241,O75116,P15311,P55196,Q9Y4G8 10 +Regulation of autophagy 0.2349355066080544 0.1953473904311304 0.8451209994324409 1.0 1.0 103 Q05639,Q00535,Q9Y5K8,P85037,P27544,Q9Y487,O00429,O43318,Q15382,P09429,P19474,P40763,P19784,Q96EB6,Q6PKG0,O95352,Q9UHD2,P42858,Q9Y5X3,P42574,Q15042 21 +Telomere capping 0.2608565438754054 0.1948418729103267 0.8455167405989648 1.0 1.0 13 Q9UBB9,P18887,P78527,Q9NYB0,O60934,Q14103,P27361,Q13315,Q15554,P28482,Q92878,Q93009 12 +Spermatid differentiation 0.2701016659374465 0.1945700955250152 0.8457295159095581 1.0 1.0 22 Q15645,Q14997,Q08J23,Q96PU8,Q9H6S0,Q96SB4 6 +Positive regulation of extracellular matrix disassembly 0.6310447761194085 0.1940127254930247 0.846165917722596 1.0 1.0 2 Q7Z460 1 +Regulation of extracellular matrix disassembly 0.6310447761194085 0.1940127254930247 0.846165917722596 1.0 1.0 2 Q7Z460 1 +Morphogenesis of embryonic epithelium 0.2700800901310491 0.1936079533096387 0.8464828701893976 1.0 1.0 26 P11586,P62081,Q9ULT8,Q13043,Q92990,O00330,P25440,Q96Q89,P42574,P07737,O95487,P17612 12 +Positive regulation of apoptotic signaling pathway 0.2677746227033349 0.1929983312197421 0.8469602750142948 1.0 1.0 30 Q96EB6,P21359,P62081,O00429,P49327,O75569 6 +Developmental maturation 0.2464719276339964 0.1924636172245079 0.8473790643594385 1.0 1.0 42 P11413,P21359,P48444,P63104,Q15645,O14965,Q8IXJ6,Q08J23,Q8NHU6,Q9BXS5,Q15334,Q5TAX3,P18074,Q15058,O75179 15 +Regulation of hepatic stellate cell activation 0.6295522388059757 0.1916043995753055 0.8480520960065765 1.0 1.0 2 P48506 1 +Dna replication independent chromatin organization 0.3056779189813735 0.1905981070411004 0.8488404733678172 1.0 1.0 6 O14929,Q8TEX9 2 +Diadenosine polyphosphate metabolic process 0.4341899753847423 0.1904304554075389 0.8489718343361532 1.0 1.0 3 Q9BW91 1 +Late endosome to vacuole transport 0.325963549447262 0.19032947615315 0.8490509571677187 1.0 1.0 5 Q99570,Q8WUX9,Q92783,Q9NZZ3 4 +Regulation of production of small rna involved in gene silencing by rna 0.2795927352985904 0.1901535346958564 0.8491888206644651 1.0 1.0 8 Q08209 1 +Negative regulation of dna binding transcription factor activity 0.2658674916738704 0.1898791895955963 0.8494038000923487 1.0 1.0 31 Q96EB6,Q96BN8,Q9GZT9,P42771,O60826,P19474 6 +Histone exchange 0.3255356009293912 0.189348637226324 0.8498195777281266 1.0 1.0 5 Q14997 1 +Negative regulation of cell growth 0.2673021265128864 0.1892706088043707 0.8498807297377093 1.0 1.0 29 Q96EB6,P11413,Q8N0X7,Q9P0J0,P42771,Q9P265 6 +Ameboidal type cell migration 0.2059652297434263 0.1892150328737043 0.8499242859539207 1.0 1.0 75 Q96EB6,Q8WTV0,P21359,P35080,Q9P258,P43034,Q7Z460,P19174,Q15555,Q14185,Q14155,P09429,P67870,Q06124,O75116,Q9NPQ8,Q16512 17 +Cellular response to molecule of bacterial origin 0.2643888688620311 0.1885316142404272 0.8504599352600208 1.0 1.0 32 Q8WTV0,P17655,Q9Y263 3 +Positive regulation of response to dna damage stimulus 0.2397157023291005 0.1884857639115752 0.8504958742671564 1.0 1.0 44 Q99504,Q9BUR4,P09429,Q7Z4V5,Q06787,Q13535 6 +Regulation of sprouting angiogenesis 0.6274626865671697 0.1882690593144299 0.8506657387133274 1.0 1.0 2 P14618 1 +Positive regulation of sprouting angiogenesis 0.6274626865671697 0.1882690593144299 0.8506657387133274 1.0 1.0 2 P14618 1 +Rna phosphodiester bond hydrolysis endonucleolytic 0.2642708736361336 0.1881633084795104 0.8507486342892332 1.0 1.0 32 Q96F86,O15091,Q9UQ84,O75818 4 +Neuron cellular homeostasis 0.2915104138769336 0.1875106976509183 0.8512602369330315 1.0 1.0 7 P78559,Q00535 2 +Chemokine production 0.2781100478468873 0.1864644501543187 0.8520805545934595 1.0 1.0 8 P09601,P78540,O00571,P14174,Q96RT1,P09429,P19525 7 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.2649338086280489 0.1861544300514501 0.8523236587995566 1.0 1.0 9 P67809 1 +Crd mediated mrna stabilization 0.2649338086280489 0.1861544300514501 0.8523236587995566 1.0 1.0 9 P67809 1 +Pigmentation 0.2568411737459174 0.1842843103777158 0.853790421642072 1.0 1.0 13 P21359,P48444,O00203,Q9BXS5,O14617,Q9H267 6 +Regulation of cell junction assembly 0.2640046311278091 0.1841743735144577 0.8538766625514878 1.0 1.0 31 P41440,Q96QK1,Q96AC1,Q13464,Q9HCM4,Q9P258,Q7Z460,Q9H6U6,Q9H2G2,P51452,Q04637,O75116,P17612 13 +Telomerase rna localization 0.2612675698398091 0.1840991177854046 0.8539356985564224 1.0 1.0 16 P49368,P50991,Q9BUR4,P40227,Q96HR8,P17987,P48643 7 +Type i interferon production 0.2660600800307002 0.1838856927244155 0.8541031289679855 1.0 1.0 28 P41440,Q9BUI4,O14802,Q9NUD5,Q9UHD2,Q06124,P19474,Q8TAT6 8 +Peptidyl proline hydroxylation 0.2632899948115679 0.1820667843510756 0.8555303152749416 1.0 1.0 9 Q9GZT9,P13674 2 +Negative regulation of neuron differentiation 0.2882166289611688 0.1795969666160116 0.8574689862508551 1.0 1.0 7 P26196,P06730,Q15648 3 +Hematopoietic stem cell proliferation 0.3008881743521726 0.1792027491705671 0.8577785051443982 1.0 1.0 6 Q15020 1 +Replication fork processing 0.2621190383424633 0.1791994922943617 0.8577810623641742 1.0 1.0 9 Q13535 1 +Muscle cell migration 0.2509510034764209 0.1788004936944786 0.8580943576183571 1.0 1.0 11 Q96N67 1 +Synaptic vesicle exocytosis 0.2611646514368995 0.1778728875660977 0.85882280386539 1.0 1.0 18 Q4J6C6,Q06787,Q15042,P35080 4 +Protein hydroxylation 0.2574262953465445 0.1777449071730049 0.8589233159251515 1.0 1.0 15 Q9GZT9,Q32P28,P13674,Q96AY3 4 +Auditory receptor cell morphogenesis 0.3408004778972437 0.1772863877147479 0.8592834424638485 1.0 1.0 4 Q14651,O14745,O95487 3 +Sprouting angiogenesis 0.2522481487291612 0.1772217744110505 0.859334192862431 1.0 1.0 12 Q96BN8,P14618,Q8NCW5,P60953,O00443 5 +Cell morphogenesis involved in differentiation 0.2545224318248671 0.1754421744833157 0.8607322040079259 1.0 1.0 129 Q9Y696,P41440,Q00535,Q9UQB8,Q6IBS0,P78559,Q16512,Q14999,O00401,Q9BPU6,Q96N67,P00492,P33176,P16949,Q9BTW9,Q96AC1,Q96TA1,Q08209,Q8TEW0,P35579,Q66K74,Q8N0X7,Q9P258,Q13618,Q15334,Q14185,Q05086,O60678,Q14155,Q9P265,Q06124,O95487,P50570,Q13153,P43034,O60568,Q15058,Q93008,P46109,P42574 40 +Cell fate determination 0.3396057347670185 0.174830614567887 0.8612127318570235 1.0 1.0 4 P60953,Q92908,Q07820 3 +Epithelial cell differentiation involved in kidney development 0.339605734767014 0.1748306145678776 0.8612127318570308 1.0 1.0 4 O95747,P46940,P42224 3 +Cell differentiation involved in kidney development 0.339605734767014 0.1748306145678776 0.8612127318570308 1.0 1.0 4 O95747,P46940,P42224 3 +Embryonic hindlimb morphogenesis 0.3396057347670103 0.1748306145678703 0.8612127318570366 1.0 1.0 4 O95747,Q15648,Q9P2D1 3 +Hindlimb morphogenesis 0.3396057347670103 0.1748306145678703 0.8612127318570366 1.0 1.0 4 O95747,Q15648,Q9P2D1 3 +Trachea morphogenesis 0.3396057347670068 0.1748306145678629 0.8612127318570424 1.0 1.0 4 P28482,Q02750,P27361 3 +Trachea development 0.3396057347670068 0.1748306145678629 0.8612127318570424 1.0 1.0 4 P28482,Q02750,P27361 3 +Trachea formation 0.3396057347670068 0.1748306145678629 0.8612127318570424 1.0 1.0 4 P28482,Q02750,P27361 3 +Toxin metabolic process 0.4252015527023028 0.1744439760886556 0.8615165561780773 1.0 1.0 3 Q9HBK9,O75592 2 +Import into nucleus 0.1976617209923388 0.1732463112964163 0.8624578228163864 1.0 1.0 70 P21359,O15397,O00629,Q9H8V3,Q9Y5L0,P61960,P40763,P61970,Q96P70,Q08209,Q7Z4Q2 11 +Response to mitochondrial depolarisation 0.2851280591787839 0.1724009928934674 0.8631222916504475 1.0 1.0 7 Q13501 1 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6170149253731403 0.172228151477312 0.8632581668745449 1.0 1.0 2 Q13043 1 +Negative regulation of cellular macromolecule biosynthetic process 0.2336515345583645 0.1722266871401965 0.8632593180460968 1.0 1.0 107 Q9C0B1,Q92900,Q5TAX3,Q92600,Q6L8Q7,O75116,Q06787,P27544,P26196,P51114,P07814,Q96BK5,Q969T7,Q86TB9,Q96TA1,P40763,P51116,Q6Y7W6,Q6PKG0,Q13464,Q5PRF9,Q9UIV1,P00374,O75534,Q8IZH2,Q04637,Q9HCE1,Q29RF7,Q7Z5K2,Q7Z7L1,Q9Y2L1,Q13535,P05198,Q96C86,P06730,O60573,P67809,A5YKK6,Q86W50 39 +Epithelial tube formation 0.2622096625405526 0.1720414836676174 0.8634049159365123 1.0 1.0 23 P11586,P62081,Q9ULT8,Q13043,Q92990,P25440,Q96Q89,P42574,P07737,O95487 10 +Response to tumor necrosis factor 0.249709167292756 0.1715029075584112 0.8638283444134549 1.0 1.0 38 Q96EB6,Q14790,Q96BN8,P61086,P63241,Q9Y5A7,P49327,P42574,P28482,Q9H6S0,Q92974,O15111 12 +Glomerular visceral epithelial cell migration 0.6155223880597074 0.1700230554557273 0.8649920049982918 1.0 1.0 2 Q13464 1 +Activation of protein kinase activity 0.2602106061726418 0.1692496945395994 0.8656002429759784 1.0 1.0 21 Q9H8V3,Q15058,O43318,Q9UER7,Q96JP5 5 +Hormone mediated signaling pathway 0.2342765806166883 0.1685761549670418 0.8661300376858383 1.0 1.0 44 Q96EB6,O95071,Q05086,Q9UER7,P61960,P67870,Q06124,Q16512,Q13309 9 +Regulation of map kinase activity 0.2599182785929158 0.1685131464020699 0.866179602226232 1.0 1.0 21 O43318,Q16512,P31689,P21359 4 +Supramolecular fiber organization 0.2909824430408064 0.1683800555853218 0.8662842974235394 1.0 1.0 175 P47756,P62993,Q9Y295,Q9UQB8,Q7Z460,Q96IZ0,Q6IBS0,O75116,P78559,Q16512,P47755,P57737,O15020,O00401,Q14008,Q99996,P04075,P35611,O15344,Q96S59,Q96CW5,P08238,P16949,Q9BTW9,P35241,P29372,Q96AY3,Q92974,Q96AC1,P60981,Q99661,P49407,P21359,Q66K74,Q13464,Q13045,O15357,Q13526,Q13618,P04350,Q9BSJ2,Q14203,Q9UEY8,Q14155,Q96P70,Q99471,Q9UIS9,Q15691,Q13153,P43034,P36404,Q03001,O60610,O60568,Q9Y5K6,P13674,Q15058,Q93008,P35080,Q14204,P07737,Q9Y613,P15311,Q9BPX3 64 +Lymphocyte activation 0.2307033551331973 0.1676839123011795 0.8668319530995867 1.0 1.0 105 Q9Y3I1,P00813,Q92990,P41240,Q96IZ0,Q16512,Q9UQ84,P00492,P46379,P12268,P09429,P51452,Q08209,P40763,Q9ULT8,Q9HCL2,Q14790,Q9Y4B6,P52701,Q06124,P62753,P24390,Q6IBW4,P00491,P42574,Q9UHD2,O15347,O00203,P17812,Q00534,Q96FZ2 31 +Carbohydrate transmembrane transport 0.2532927333862154 0.1675954135586743 0.866901579614882 1.0 1.0 15 P31751 1 +Male meiosis i 0.6134328358209016 0.1669721846958946 0.8673919350491552 1.0 1.0 2 Q15645 1 +Regulation of canonical wnt signaling pathway 0.2461378771701564 0.1666394011935762 0.8676537894669218 1.0 1.0 39 Q9HCK8,Q04727,Q13526,Q96QK1,Q96K76,Q96BN8,O95071,Q16539,Q13283,Q99471,P40818 11 +Transposition 0.4205750000008911 0.166626212515363 0.8676641674251055 1.0 1.0 3 Q5TAX3 1 +Regulation of transposition 0.4205750000008911 0.166626212515363 0.8676641674251055 1.0 1.0 3 Q5TAX3 1 +Cell junction assembly 0.2013151484955146 0.1666148214874554 0.8676731308596111 1.0 1.0 75 O00560,P41440,Q00535,O43815,Q13177,O00192,P60953,Q9H6U6,Q7Z460,P55196,O75116,O15020,Q96QK1,Q9HCM4,P51452,Q9BTW9,Q96AC1,Q8TEW0,Q13464,Q9P258,Q14155,Q04637,Q96HC4,Q9Y490,Q16513,Q03001,P36404,Q9H8V3,Q9H2G2,P46109,Q9H7S9,P17612,P12814,Q8NI35 34 +Negative regulation by host of viral transcription 0.4204240071663185 0.1663757789859548 0.8678612338566136 1.0 1.0 3 P17980,Q13547 2 +Imp catabolic process 0.6128358208955285 0.1661082729391847 0.8680717437412024 1.0 1.0 2 P00491 1 +Positive regulation of protein depolymerization 0.3351254480286603 0.1658472782006496 0.8682771386646726 1.0 1.0 4 O75083,P60981,Q9Y281 3 +Transcription elongation from rna polymerase i promoter 0.3349327702522796 0.1654689472884915 0.8685748893702829 1.0 1.0 4 P18074 1 +Cellular component disassembly 0.2774036385964466 0.1653308561701858 0.8686835732875204 1.0 1.0 159 P47756,Q9Y3I1,P41440,Q00535,P61221,P53350,Q7Z460,Q7Z6Z7,Q9NT62,Q15555,Q99570,Q6IBS0,Q9ULC4,Q9Y4P1,P78559,P47755,P27544,O15020,Q14008,P35611,O15344,P62495,O00429,P46199,P61960,P33176,P16949,P51452,Q96E11,P35241,Q92974,P29372,P60981,Q99661,P19784,Q01105,Q66K74,Q9Y4P8,P41214,Q14203,P63241,Q9UEY8,Q9Y5B9,A1X283,P50851,Q9H269,Q9UPY3,O95352,Q9NRR5,Q92538,P43034,Q99986,Q15058,P42858,O75351,Q13501,P54920,Q9BPX3 58 +Sensory perception 0.2412195378494825 0.1652756717812463 0.8687270065761803 1.0 1.0 41 Q99504,Q15555,Q13432,Q00169,O75569,P49419,P42574,Q9BPW8,Q3SYG4 9 +N acetylneuraminate metabolic process 0.3348251928127863 0.1652580017309643 0.8687409140059845 1.0 1.0 4 P46926,Q9UJ70 2 +Positive regulation of cytokine production involved in immune response 0.2489404549284949 0.1649364650536051 0.8689939904805561 1.0 1.0 13 Q96EB6,O43318 2 +Ear morphogenesis 0.2518927743603854 0.1642774357085577 0.8695127440585535 1.0 1.0 15 P28482,O75569 2 +Positive regulation of binding 0.196485103829733 0.1641773147874946 0.8695915589532246 1.0 1.0 54 P41440,Q00535,P18074,Q06787,P35611,P08238,P09429,O15371,P16949,Q96BK5,P19474,Q96TA1,Q13526,Q8IXJ6,O00330,Q04637,P14735,P05198,P15531,Q96D46,Q15691 21 +Alditol biosynthetic process 0.4189310241863192 0.1639155635527459 0.8697976148745092 1.0 1.0 3 P17174,A6NDG6 2 +Cytoskeleton dependent intracellular transport 0.187509354381235 0.1638310858172823 0.86986411936209 1.0 1.0 62 Q9UBF2,P78559,O60333,O00401,Q9UH99,P33176,Q9BW83,Q66K74,Q9Y2T2,P07437,Q14203,Q9UIS9,Q9NZ32,P43034,O00203,P42858,Q8TD16,Q14204,P27695 19 +Actomyosin structure organization 0.2048675257450186 0.1633644523746764 0.870231489743754 1.0 1.0 52 Q13177,Q7Z460,P60953,Q92614,O75116,Q16512,Q9HCM4,Q8WUM4,P16949,Q96AC1,Q9UN37,P49407,P35579,Q13464,Q13045,Q99439,Q13618,Q12802,Q13153,Q9H8V3,P35080,P07737,Q9Y613 23 +Hyaluronan biosynthetic process 0.610447761194036 0.1626871069409132 0.8707647989130742 1.0 1.0 2 Q00610 1 +Hyaluronan metabolic process 0.610447761194036 0.1626871069409132 0.8707647989130742 1.0 1.0 2 Q00610 1 +Regulation of hyaluronan biosynthetic process 0.610447761194036 0.1626871069409132 0.8707647989130742 1.0 1.0 2 Q00610 1 +Dna recombination 0.2284771280610693 0.1623447816380869 0.871034351739985 1.0 1.0 104 P25205,Q9BUR4,Q9Y3Z3,P18074,Q9UQ84,O00487,Q9H4L7,P35244,P38935,P46063,O60921,P09429,Q7Z4V5,P18858,Q15645,P20585,P52701,Q96T76,Q9Y620,Q96FZ2,P27695 21 +Dna damage induced protein phosphorylation 0.3329748819361308 0.161662001368535 0.8715720293663871 1.0 1.0 4 O96017 1 +Blastocyst development 0.2513552480757623 0.1610676903266787 0.8720400873327905 1.0 1.0 35 Q9BRT9,P61201,P00813,P43686,Q6W2J9,P17655,Q13618,Q8IWS0,A5YKK6,P31350 10 +Response to molecule of bacterial origin 0.232057075993837 0.1609674216952342 0.8721190597165758 1.0 1.0 44 Q8WTV0,Q9Y263,Q14790,P17655,P09429,P42574,P28482 7 +Regulation of telomerase activity 0.2567924188265872 0.1608149308587735 0.8722391651737416 1.0 1.0 21 P07900,Q9BUR4,P08238,Q96HR8,Q96BK5,P28482,P17987,P13010,P27544 9 +Vacuolar transport 0.2420684194403289 0.1606590301866016 0.8723619593445411 1.0 1.0 40 Q9H269,P20645,Q7Z3T8 3 +Positive regulation of endothelial cell migration 0.2570349333557669 0.1600334994020252 0.8728546855786812 1.0 1.0 22 O75116,Q8WTV0,Q96EB6,P09429 4 +Postsynaptic membrane organization 0.266746411483251 0.1599989811095537 0.8728818768346212 1.0 1.0 8 Q9UPY5,Q9NQX3,Q96EY1,Q15334,P19022,P46109,O15258 7 +Actin filament organization 0.230540623773525 0.1593834006057556 0.8733668161329258 1.0 1.0 107 P47756,P62993,Q9UQB8,Q7Z460,Q96IZ0,Q6IBS0,O75116,Q16512,P47755,P57737,O15020,O00401,P04075,P35611,P16949,P35241,Q96AC1,Q92974,P60981,P49407,Q13464,Q13045,O15357,Q13618,Q9UEY8,Q13153,O60610,Q9Y5K6,P35080,P07737,Q9Y613,P15311,Q9BPX3 33 +Cellular process involved in reproduction in multicellular organism 0.1822616996458394 0.1585060216448539 0.8740580760608598 1.0 1.0 58 Q6IBW4,Q15645,O14965,Q14997,Q08J23,Q8NHU6,O95067,Q5TAX3,Q96PU8,P62753,Q9H6S0,Q96SB4 12 +Negative regulation of cell cell adhesion 0.2562817184578492 0.1582186949978037 0.8742844728213264 1.0 1.0 22 Q92990,Q96IZ0,P09429,P51452,P42574 5 +Presynapse organization 0.3110231930086328 0.1581778206425091 0.8743166802831508 1.0 1.0 5 Q96QK1,Q04637 2 +Organonitrogen compound biosynthetic process 0.2097018004092425 0.1577764479961871 0.8746329579567551 1.0 1.0 586 P11310,Q05639,P17655,O60502,Q96IZ0,O75116,P54136,O95394,P27544,O60701,P38935,P14618,P26196,P26639,P62847,P27635,P33316,P46199,Q13126,Q7Z7F7,Q92499,Q9BY44,Q99707,Q567V2,P31751,Q8TEQ6,O00330,O75534,P13639,Q14240,P18621,O95352,P26572,Q9BZX2,P26640,Q99805,P17812,O94822,Q96P11,Q9NVE7,Q8N3C0,P49419,P67809,Q86W50,Q15042,Q9Y285,P49770,P46776,Q9BX40,P00813,Q9Y295,Q9P2J5,Q9C0B1,Q14232,Q5TAX3,Q9ULC4,Q13310,P29692,P27708,P22392,O96017,P41567,O60256,O43505,Q06203,P30520,P04075,P32969,P49915,P62701,P62495,P08708,Q06210,P51114,P48506,P47897,P42766,P41252,P39019,Q96E11,Q86TB9,Q969T7,Q969G6,P49903,O00154,Q6Y7W6,Q96I59,Q9Y4P8,Q13144,Q96JB2,Q9Y262,Q9UIV1,P08397,Q01433,P07741,Q9UET6,P05387,Q9HCE1,P43490,P62899,P15880,Q9Y2L1,P11586,P05198,P00491,Q9BV10,P15531,O60568,P35790,P39023,P62266,O15067,P11172,Q06787,Q14353,Q7Z478,P62854,P08243,P31939,P40763,P41214,O96007,P00374,P20248,Q13057,Q92616,Q8NE71,Q8WUX2,Q92905,Q96C86,Q9BQC3,Q9Y450,O75821,P26641,P60866,P62917,P61221,Q14152,P62081,O60841,P00492,P22059,P53396,Q96PU8,Q99873,Q9NRN7,Q9NSD9,Q6PKG0,O43776,O60294,P63241,P20839,P62753,P49589,P12277,P30566 156 +Vasculature development 0.2251857670328176 0.1566271064095313 0.8755387383801188 1.0 1.0 102 Q9Y696,Q92990,Q9BXJ9,O75116,Q14999,P14618,P19174,P26358,Q96PU8,Q96AY3,Q15648,Q96TA1,P40763,P78362,P21359,Q96EB6,Q9ULT8,Q14790,P20248,P28482,O95487,Q96BN8,Q9GZT9,Q92688,Q9NPQ8,O75179 26 +Positive regulation of defense response 0.2384059655306384 0.1563794048561665 0.8757339699941473 1.0 1.0 41 Q9BUI4,Q9NUD5,Q9UHD2,Q15648,P55212,O43318,P30046,P09429,Q9NW08,Q16512 10 +Positive regulation of neuron projection development 0.2549474334819815 0.154971149300505 0.8768440620162079 1.0 1.0 29 Q9UQB8 1 +Epithelial structure maintenance 0.6047761194029913 0.1547825027867575 0.8769927857124082 1.0 1.0 2 Q9Y3F4 1 +Regulation of lymphocyte activation 0.183405848010575 0.1542741070131806 0.8773936124926189 1.0 1.0 60 Q9Y3I1,P00813,P00491,Q9HCL2,P42574,Q92990,P41240,O15347,Q96IZ0,P09429,Q06124,Q96FZ2,Q16512 13 +Regulation of mitotic sister chromatid segregation 0.2553443130527448 0.1542295211740568 0.877428766131469 1.0 1.0 24 Q9H900,O60566,Q15645,P33981,P53350,O43684,O43264,Q969U7,P50748,P14635,Q9Y6G9 11 +Cellular macromolecule biosynthetic process 0.2228554486215206 0.154056706003822 0.8775650242802926 1.0 1.0 570 P11310,Q05639,P25205,O60502,Q9Y3Z3,Q96IZ0,O75116,P54136,O95394,P27544,O60701,P35244,P38935,P14618,P26196,P26639,P62847,P27635,P49427,P46199,P33316,Q7Z7F7,P46063,Q92499,Q96TA1,Q9UPR3,P18858,P78362,Q01105,Q9UBD5,Q9BY44,Q567V2,P31751,Q8TEQ6,O75534,P04183,P13639,P13807,Q14240,P17987,P18621,O95352,Q13535,P46976,P26572,P26640,Q99805,Q96P11,O94822,Q8N3C0,P67809,Q86W50,Q15042,Q9BRT9,Q9Y285,P49770,P46776,Q9BX40,Q9Y295,Q9P2J5,Q9BUR4,Q9C0B1,Q14232,Q5TAX3,Q9ULC4,Q13310,P29692,P49005,P41567,O75717,P23921,P31350,O43505,P32969,P62701,P62495,P08708,Q06210,P51114,P47897,P42766,P41252,P39748,P39019,Q96BK5,Q96E11,Q86TB9,Q969T7,P28340,Q6Y7W6,Q96I59,Q9Y4P8,Q13144,Q96JB2,Q9Y262,Q9UIV1,Q9UET6,P05387,Q9HCE1,P62899,Q7Z7L1,Q9Y2L1,P15880,P05198,Q9BV10,O60568,Q07864,P39023,P62266,P46783,P62841,P41440,Q9BTE3,Q06787,Q7Z478,P62854,P40763,P49642,Q96EB6,P41214,P00374,P20248,Q92616,Q7Z5K2,Q8NE71,Q92905,Q96C86,Q9BQC3,Q9Y450,O75179,O75821,P26641,P60866,P62917,P61221,Q92547,Q96HR8,Q14152,P62081,O60841,Q96PU8,Q99873,Q9NSD9,Q6PKG0,O43776,P63241,P62753,P28482,P49589 149 +Double strand break repair 0.2215014210564215 0.1531928515747729 0.8782461947519957 1.0 1.0 99 Q96T76,Q9H4L7,P35244,Q15645,Q9NUW8,P25205,Q9BUR4,Q9Y3Z3,Q99504,P46063,O95071,O60921,Q9Y620,P09429,Q7Z4V5,Q96FW1,Q96FZ2,O00487 18 +Endothelial cell morphogenesis 0.4119462298560162 0.1527916122109769 0.8785626125531036 1.0 1.0 3 Q9Y696 1 +Phospholipid homeostasis 0.6026865671641854 0.1519483460213243 0.8792276763598299 1.0 1.0 2 Q9HCL2 1 +Cell junction organization 0.2439046565877258 0.1517021239296518 0.8794218819098272 1.0 1.0 124 O00560,P41440,Q00535,O43815,Q9UQB8,Q13177,Q7Z460,P60953,O00192,Q9H6U6,Q16539,P41240,Q15555,O75116,Q7L576,O15020,O00401,Q96QK1,P63104,Q9HCM4,P35611,P51452,Q9BTW9,P35241,Q96AC1,Q8TEW0,Q13526,Q13464,Q9P258,P61160,Q15334,Q14203,P07437,Q05086,O60678,Q14155,Q96HC4,Q04637,Q9Y490,Q16513,Q14012,P43034,P36404,Q03001,Q9H8V3,Q9H2G2,P46109,Q9H7S9,P35080,P17612,P07737,P12814,Q8NI35,Q13614 54 +Anion homeostasis 0.2755532506202007 0.1514807643071535 0.8795964835945669 1.0 1.0 7 Q9Y666 1 +Blood vessel endothelial cell migration 0.2538225317104265 0.1513704026695376 0.8796835356589883 1.0 1.0 23 Q96EB6,Q8WTV0,P21359,P09429,P67870 5 +Proteasome mediated ubiquitin dependent protein catabolic process 0.2498209239113439 0.1509725255129422 0.8799973889155881 1.0 1.0 131 O00560,P62191,P43686,Q13200,P62333,Q92990,P53350,Q7Z6Z7,Q93034,Q15008,Q14258,Q96KB5,P25787,P78559,Q86UK7,O00487,Q13309,Q13616,Q13619,O14980,Q04323,P49427,P46379,P55036,P48506,P45974,P08238,O75832,Q8IWV7,Q13617,Q9Y5A7,P49407,Q96EB6,Q9ULT8,Q9Y263,Q8IXJ6,O14965,Q13618,P61086,Q9UL15,Q9UJX4,O95376,Q9Y5K5,Q8IUR7,Q8TAT6,Q9NRR5,O94966,Q9UJX5,Q9BW61,Q9Y5K6,Q5VYK3,Q15058,O94822,Q8N3C0,P62195,Q16763 56 +Defense response to symbiont 0.1866047463736068 0.1503458814083819 0.8804917362106974 1.0 1.0 64 Q9UII4,Q9BUI4,O14802,Q9NUD5,Q9Y3Z3,Q92499,Q14258,O75179,P19474,Q9NW08,Q8TAT6,Q13309,O95352,Q7Z7L1 14 +Amyloid beta clearance 0.2493302337776355 0.150296495785925 0.8805306975461547 1.0 1.0 9 P14735,Q00610,Q13464 3 +Chaperone mediated protein complex assembly 0.2382827397331536 0.1497902663540598 0.8809300890378333 1.0 1.0 11 O95456 1 +Regulation of muscle organ development 0.2487141521699308 0.1490154837361967 0.8815414151245531 1.0 1.0 9 P41440,Q96TA1,O94966 3 +Sarcoplasmic reticulum calcium ion transport 0.2612723753070222 0.1483942669657626 0.8820316242807442 1.0 1.0 8 P78417 1 +Epithelial tube morphogenesis 0.2377344764714245 0.1477048399346294 0.8825757118222588 1.0 1.0 40 P11586,Q9Y696,P62081,Q9ULT8,Q13153,Q13043,P42574,Q92990,P25440,Q96Q89,P67870,P17612,Q15648,Q16512,O95487,P07737 16 +Regulation of vesicle mediated transport 0.2363657537398488 0.1469948944603479 0.8831360501765868 1.0 1.0 117 Q13614,P41440,Q00535,P41240,Q9NT62,Q92614,Q06787,Q9UL63,P22681,Q8WTV0,O60343,Q9Y6B6,P36507,P09429,Q08209,Q4J6C6,Q96T51,P31751,Q13432,O60493,P28482,Q9H4M9,Q7Z3T8,Q9Y5K6,P35080,Q15042,P27695 27 +Signal transduction by p53 class mediator 0.2186882918727093 0.1466712550672401 0.8833915083212587 1.0 1.0 47 Q96EB6,P62081,P60866,O14965,P46379,P55212,P63241,Q96RU2,Q13535 9 +Regulation of innate immune response 0.2117903986094167 0.146134292319307 0.8838153756366787 1.0 1.0 49 Q9BUI4,Q14790,Q9NUD5,Q9UHD2,Q9Y3Z3,Q15648,P55212,O43318,P09429,Q06124,P19474,Q9NW08,Q16512 13 +Motor neuron axon guidance 0.3044517478338727 0.1454057531389097 0.88439052259189 1.0 1.0 5 O75592,P84095,P63000,Q00535 4 +Cell cycle 0.2457582070770448 0.1452307660293796 0.8845286756599364 1.0 1.0 532 O00560,O00410,Q9BV86,P33992,Q00535,P61254,Q7Z460,P25205,P60953,P52564,Q99570,P46940,Q9BT25,Q9BUF5,Q9GZZ1,Q6P1K2,O75116,Q96DY7,Q9UQ84,P50748,Q14999,Q53EL6,O00299,Q13616,Q9H4L7,Q15392,P35244,O60566,Q9UH99,P49427,P11802,O60921,Q96CW5,Q15382,Q96RU2,Q15648,Q13617,P18858,Q99661,P78362,Q9UPT9,Q9H900,Q9P258,Q9Y570,Q08J23,P31751,Q13535,P50570,P43034,P36404,Q93008,Q14204,Q15398,Q9BPX3,Q9Y3I1,Q9Y295,Q9P0V9,Q9HBM1,Q9H6H4,O95067,Q9ULC4,Q96Q89,Q7L2J0,O96017,O75717,P31350,P23921,O00743,O00401,P39748,Q9BTW9,Q96BK5,Q92974,Q08209,Q8TEW0,P40818,Q2NKX8,Q6Y7W6,Q15257,Q7Z4H7,Q9BSJ2,Q9UJX4,Q13432,Q9NTJ3,Q16513,Q9UIS9,Q7Z7L1,Q9HC35,O95373,O94966,P43487,O75935,Q07864,P42858,Q00534,Q9Y620,Q15021,Q15003,Q13885,P63172,Q969U7,Q8TCY9,Q15691,P52732,Q16763,Q96K76,Q6NUK4,Q69YH5,Q9BTE3,Q93034,Q16539,P42771,Q15813,P18074,Q96CT7,Q96KB5,Q14166,Q14008,Q13619,Q9NR09,O14980,P68036,O43684,O95905,P61289,P08243,P16949,P51452,P19474,P35241,P40763,P19784,Q96EB6,P35579,Q8TBC4,Q8IXJ6,Q13618,Q15334,Q14203,P20248,Q06124,Q04637,Q13564,Q9Y5K5,Q7Z5K2,Q92538,Q92905,O75150,Q99986,P06730,Q9H8V3,O95347,O75909,O75351,Q5VTR2,O43264,O75179,O95630,P14635,P15311,P27695,P68371,P33981,P53350,P42695,Q8TD19,Q15555,Q92900,Q92547,Q9H6S0,Q96DE0,Q13309,Q9Y6G9,Q9NXR7,Q9NRZ9,Q9BY42,P46379,Q9Y3P9,P08238,O75832,O15355,O43683,P78344,Q9UII4,P33991,Q13526,Q13464,Q15645,P83731,O14965,Q14141,P04350,P43246,P07437,Q8IX90,P30307,Q8TAE8,P52701,P62753,P28482,P17612,Q29RF7,Q14012,Q6IBW4,Q99741,Q9Y4A5,Q9UJX5,Q9NYV4,Q9Y5K6,Q15058,O14744,Q00610,P42574,O95239 214 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.2296623236485394 0.1447582195911938 0.8849017706158548 1.0 1.0 43 P62191,P43686,P62333,P53350,O60826,Q06787,P46379,P48506,P45974,O75832,O43765,Q9Y5A7,Q9ULT8,O14965,Q8IXJ6,O95376,Q9Y4X5,O75150,Q9BW61,P62195 20 +Regulation of cytosolic calcium ion concentration 0.2505534982877158 0.1431903552001645 0.8861398467650397 1.0 1.0 24 P19174,P42858,P09429,P78417,P28161,P27695 6 +Cellular transition metal ion homeostasis 0.2473309193920087 0.1430882193666324 0.8862205087862718 1.0 1.0 19 Q9Y487,O75880 2 +Hyperosmotic response 0.2457284544316668 0.1429514138563242 0.8863285531153164 1.0 1.0 9 P13010,Q16512,Q92974 3 +Pattern recognition receptor signaling pathway 0.2437342503375783 0.1405818910964297 0.8882002549592614 1.0 1.0 35 P41440,Q96BN8,Q9NUD5,O43318,Q14258,P09429,O75179,Q01804 8 +Epithelial cell maturation 0.4037025977903815 0.1404779835129745 0.8882823466004519 1.0 1.0 3 P15121,P04818 2 +Protein targeting to mitochondrion 0.2065421073764412 0.1403848565017526 0.8883559221253745 1.0 1.0 50 O00170,Q9P0J0,P68036,Q15785,O60830,P55786,O14737 7 +Protein localization to cell surface 0.2407577108244004 0.1400226918999999 0.8886420614674719 1.0 1.0 15 P78559,Q9UJY4 2 +Axo dendritic transport 0.2490810323133941 0.1399088977526269 0.8887319710499559 1.0 1.0 28 Q9NZ32,P43034,Q03001,Q9Y2T2,P27695,O00203,Q14203,P33176,Q14204,P78559,O14617,O60333 12 +Positive regulation of intracellular signal transduction 0.2678479319854485 0.1395377399285563 0.8890252354856121 1.0 1.0 157 P60866,P00813,Q9UMX5,Q9NUD5,P41240,Q15555,Q14258,O60826,O75116,Q16512,P22681,P62081,P36507,O00429,O43318,P30046,Q15382,P09429,P19474,P29372,Q96AC1,Q99873,Q96EB6,Q14790,Q05086,Q06124,O75569,Q13535,Q92734,Q9H8V3,P18615,O75179 32 +Organelle transport along microtubule 0.2485449294481404 0.1395004583008668 0.889054693809292 1.0 1.0 29 Q66K74,Q9NZ32,P43034,Q9Y2T2,O00203,P42858,Q8TD16,Q9UBF2,Q14204,P27695 10 +Glutamine family amino acid metabolic process 0.2470882189043853 0.1387870924343376 0.8896183940133258 1.0 1.0 31 Q06203,P49915,Q9NQR4,Q06210,P17812,P48506,P08243,P27708,O15067 9 +Cellular response to stress 0.1711259465883232 0.1375753110698966 0.8905760688707118 1.0 1.0 499 P25205,Q7Z6Z7,Q9Y3Z3,Q96IZ0,O75116,Q9UQ84,Q9H4L7,P35244,P38935,O60921,Q7Z4V5,Q96RU2,P18858,Q99707,P55786,O75569,O95352,Q13535,Q9BYN0,Q5VYK3,P67809,Q9BUR4,Q99956,Q9ULC4,Q9UER7,Q16512,P49005,P23921,P22681,Q99504,Q14997,P61960,P28340,P21359,Q92759,Q13144,P57081,Q7Z7L1,P36915,Q07864,Q00534,Q9Y620,Q96FZ2,P41440,Q96K76,P42771,P18074,Q14258,Q06787,Q04323,O43318,P08243,P09429,P29372,P31689,Q96EB6,Q2TAL8,P00374,P20248,P20585,P49327,Q06124,Q92616,Q86WJ1,Q92905,Q9GZT9,Q9H8V3,Q13501,P27695,P54277,Q92547,P11413,P36507,P46379,Q96FW1,Q99873,Q15645,O95071,P52701,P28482,Q8TAT6,Q96T76,Q9H993,Q9NUW8,P42574,P28161,Q0VDF9 87 +Response to vitamin a 0.5907462686567231 0.1365536454197718 0.8913836187585558 1.0 1.0 2 P04818 1 +Receptor metabolic process 0.2438516465114027 0.1352134811023484 0.8924430886005097 1.0 1.0 33 P62993,P41440,Q00535,P50570,Q15334,Q99570,Q00610,Q9UL63,Q06787,P15311,Q9Y6D5,Q13614,P49407 13 +Positive regulation of response to cytokine stimulus 0.2329511168431322 0.1350960215946192 0.8925359556507004 1.0 1.0 12 Q15648,Q9UHD2,P61086 3 +Cytokine production involved in immune response 0.2363023227716831 0.1344805031814271 0.8930226272468329 1.0 1.0 14 Q96EB6,O43318 2 +Regulation of rna binding 0.2541619533141375 0.1344260742989826 0.8930656644419306 1.0 1.0 8 Q06787,O15371,Q04637 3 +Negative regulation of cell cycle 0.2162247433936567 0.1337540053151542 0.8935970987267972 1.0 1.0 99 O00410,Q9Y3I1,Q00535,Q96K76,P33981,P61254,P53350,Q16539,P42771,Q92547,Q96DY7,O96017,P50748,Q9H6S0,Q9Y6G9,Q13619,O60566,Q9NXR7,O43684,O60921,Q96BK5,Q96RU2,O43683,Q96EB6,Q9H900,Q6Y7W6,Q15645,Q08J23,P43246,Q06124,Q13564,Q7Z5K2,Q7Z7L1,Q13535,Q99741,O95373,Q00534,O43264,P42574,Q969U7,P14635 41 +B cell activation 0.2303453854394807 0.1332317171396111 0.8940101277894783 1.0 1.0 41 P00813,Q14790,P42574,Q96IZ0,P17812,P52701,Q96FZ2,Q16512,Q9UQ84 9 +Negative regulation of cell population proliferation 0.2214729872134862 0.1329407230179332 0.8942402604067181 1.0 1.0 105 Q92990,P41240,Q96IZ0,P42771,O14737,Q92796,Q16512,Q96DY7,Q15392,P67870,Q15648,Q96TA1,P40763,Q99627,P21359,O15357,O00330,O75569,P15531,Q00534,P42574 21 +Regulation of t cell activation 0.2342469379269823 0.1327986785968098 0.8943525994309622 1.0 1.0 39 P00491,P00813,Q9HCL2,Q92990,P41240,O00203,Q96IZ0,P09429,Q06124,P42574 10 +Autophagosome organization 0.2458270827226822 0.1325322897371146 0.8945632847621441 1.0 1.0 25 O95352,Q15042,Q9Y4P1 3 +Regulation of protein localization to chromosome telomeric region 0.2334405712064901 0.1324266951851625 0.8946468009114081 1.0 1.0 13 P49368,P50991,Q9BUR4,P40227,P17987,P48643 6 +Regulation of dna binding transcription factor activity 0.1949371077973185 0.1319870271835766 0.8949945527829404 1.0 1.0 77 Q96EB6,P41440,Q92905,Q96BN8,P60900,Q9GZT9,P42771,O43318,Q14258,O60826,P40763,P19474,Q08209 13 +Neurotransmitter secretion 0.2435912990577661 0.1318486269840636 0.8951040234874537 1.0 1.0 21 Q4J6C6,P21359,P35080,Q06787,Q15042 5 +Cellular amide metabolic process 0.1896344020539635 0.1317811171901343 0.8951574225798511 1.0 1.0 474 Q05639,O75116,P54136,P27544,O00299,O75874,P38935,P14618,P26196,P26639,P62847,P27635,P46199,Q7Z7F7,Q92499,Q9BY44,Q9HCL2,Q567V2,P31751,Q8TEQ6,P55786,O00330,O75534,P13639,P14735,Q14240,P18621,P26640,Q99805,Q96P11,O94822,P52888,Q8N3C0,P67809,Q86W50,Q9Y285,P49770,P46776,Q9BX40,P00813,Q9Y295,Q9P2J5,Q9NQW7,Q9C0B1,Q14232,Q5TAX3,Q9ULC4,Q13310,P29692,P41567,P32969,P62701,P62495,P08708,P51114,P48506,P47897,P42766,P41252,P39019,Q8IYS1,Q96E11,Q86TB9,Q969T7,O00154,Q6Y7W6,Q96I59,Q13144,Q9Y262,Q9UIV1,Q9UET6,P05387,Q9HCE1,P62899,P15880,Q9Y2L1,P05198,P00491,P39023,P62266,P46783,P62841,P48507,P41440,P78417,Q06787,Q7Z478,P62854,P08243,P40763,Q15126,P41214,P00374,P20248,Q92616,Q8NE71,Q8WUX2,Q92905,Q96C86,Q9BQC3,Q9Y450,O75821,P18669,P26641,P27695,P60866,P62917,P61221,Q86TX2,Q14152,P11413,P62081,O60841,P09960,P22059,P53396,Q96PU8,Q9NRN7,Q9NSD9,Q6PKG0,O43776,P63241,P62753,P49589,P42574,P28161,P53602 127 +Neurotransmitter gated ion channel clustering 0.3974320692744044 0.1316978777083055 0.8952232642403297 1.0 1.0 3 Q9NQX3,Q15334 2 +Epithelial to mesenchymal transition 0.2450269729488263 0.1306533803290566 0.8960495132162656 1.0 1.0 27 O75116 1 +Epithelial cell development 0.2290927779539952 0.1299408617723695 0.8966132153120345 1.0 1.0 41 Q9Y696,Q07157,P21266,Q9Y4G8,Q13464,Q9HCM4,P35611,O60568,P46940,P35241,Q00534,Q15382,P49327,P55196,O75116,P15311,P04818 17 +Trna threonylcarbamoyladenosine metabolic process 0.3148148148148078 0.1295928991319002 0.8968885215414981 1.0 1.0 4 Q9NPF4,Q7L0Y3,Q9Y606 3 +Regulation of proteolysis 0.2702272518082918 0.1289249525668753 0.8974170321468393 1.0 1.0 165 P62191,Q00535,P43686,Q96K76,Q9P0J0,Q92990,O60826,Q96KB5,O14737,P78318,O75116,P78559,Q06787,O00487,P62081,Q15392,Q9NR09,O14980,Q14997,Q04323,P46379,P48506,P45974,P61289,P09429,P19474,Q9Y5A7,P40763,P19784,Q96EB6,Q9C0C9,O43847,P35579,Q9ULT8,Q14790,Q8IXJ6,O14965,P61086,Q9UL15,Q05086,P20248,O95376,P49327,P61201,Q9Y5K5,P30086,Q16186,Q9NRR5,O94966,O75150,P04080,Q15020,Q92688,P62195,Q01804 55 +Positive regulation of organelle assembly 0.2427231034407238 0.1276684789276614 0.8984113360885151 1.0 1.0 30 O00560,Q9BPX3,Q15555,P26038,Q16181,Q8WUM4,Q9NZN8,Q9UHD8,Q6UVJ0,Q13283,Q8TBX8,Q16658,Q96C92,P42858,O75351,Q14204,A5YKK6,Q15042,P27695 19 +Somatic diversification of immunoglobulins 0.2405882220430066 0.1276548386840049 0.8984221311030824 1.0 1.0 20 Q96FZ2,P20585,Q9UQ84,P52701 4 +Erbb2 signaling pathway 0.3941475067184189 0.1272990471567587 0.8987037144311929 1.0 1.0 3 Q9UNE7,Q93034 2 +Spindle assembly 0.1912328325694727 0.1272314192603808 0.8987572384762692 1.0 1.0 53 Q9Y295,Q15691,Q7Z4H7,Q7Z460,O14965,Q15555,O95067,Q9BSJ2,P07437,Q9BT25,Q96CW5,Q14204,O96017 13 +Transforming growth factor beta receptor signaling pathway 0.242401315244166 0.1270444072733656 0.8989052513623241 1.0 1.0 23 Q96EB6,Q9Y3F4,Q13526,P50570,O43318,Q93008,P08238,Q96AC1,P40763,Q9UPN9 10 +Cerebral cortex development 0.2432365749161906 0.1269731103483425 0.8989616810972134 1.0 1.0 26 P21359,Q00535,P43034,O43776,Q15058,P31939,P19784 7 +Embryonic morphogenesis 0.195382747996638 0.1266504976324654 0.8992170273831612 1.0 1.0 79 O60701,P67809,P62081,Q9ULT8,P62753,P42574,Q92990,Q7Z460,P28482,O00330,P20248,Q96Q89,Q9NPQ8,O75116,Q15648,O75569 16 +Regulation of tor signaling 0.2400140401806876 0.1265724374809686 0.8992788131555536 1.0 1.0 20 Q96EB6,Q96B36,Q15382 3 +Dna damage response signal transduction by p53 class mediator 0.2363581924997458 0.1260790873160888 0.8996693212641675 1.0 1.0 17 Q96EB6,P61254,P14174,Q14694,O75832,O96017,Q13535 7 +Positive regulation of nuclear division 0.2291376331330288 0.1246542565778165 0.900797272802164 1.0 1.0 13 Q8IXJ6,O14965,Q13618,Q9UJX4,Q15398 5 +Programmed cell death 0.1910110978790102 0.1246024342393383 0.9008383011745202 1.0 1.0 443 Q05639,Q03164,P55210,Q00535,P17655,Q96IZ0,Q9BXJ9,O60333,Q15392,O60566,P13693,P14618,P27635,P49427,Q96RU2,Q15648,Q13617,Q96TA1,P78362,Q01105,Q9C0C9,Q9HCL2,P31751,P55212,O00330,Q14155,P17987,O75569,O95352,P24390,Q96B36,P51858,Q5VZE5,P50570,P45985,P30154,Q92688,Q9BTT0,P00813,Q9NX46,Q9P0J0,Q99956,Q9UER7,P22392,Q16512,O96017,P22681,Q13572,Q99504,P61081,P51114,P48506,P47897,P26358,P61960,Q96TC7,Q969G6,P21359,Q14790,Q15257,Q13144,P15531,P42858,Q969U7,Q96K76,Q9NT62,P42771,P18074,O14737,Q9NR09,O00429,O43318,P61289,P08243,P09429,P31689,P19784,Q96EB6,Q2TAL8,Q14185,P20248,P49327,Q13564,Q92905,Q96C86,Q9H8V3,Q13501,O95630,P27695,Q92614,Q13309,P11413,P62081,P19174,P46379,Q66K74,O14965,P63241,P52701,P62753,P28482,Q15058,P06737,P42574 104 +Positive regulation of immune response 0.198496038189106 0.1242547774847114 0.9011135520783218 1.0 1.0 83 P49770,P00813,Q9NUD5,P41240,Q96IZ0,Q9NW08,Q16512,Q9BUI4,P19174,P46379,O43318,P09429,Q15648,Q96EB6,Q13144,P55212,P28482,Q9UHD2,Q96FZ2 19 +Response to interferon alpha 0.2918830399097434 0.1233018869290204 0.9018680466831483 1.0 1.0 5 P10155 1 +Nik nf kappab signaling 0.2412821479339047 0.1231170020830999 0.90201444799162 1.0 1.0 26 Q00653,Q04206,P15311,O43318,Q53EL6,Q9UPY3,Q96JP5,P60510,Q99627,O15111 10 +Aromatic amino acid family catabolic process 0.3908629441624296 0.1230367276024065 0.902078014482632 1.0 1.0 3 P09417,P16930 2 +L phenylalanine metabolic process 0.3908629441624296 0.1230367276024065 0.902078014482632 1.0 1.0 3 P09417,P16930 2 +Protein containing complex localization 0.2108590784579075 0.1227715952930699 0.9022879677374684 1.0 1.0 47 Q9BW83,O00401,Q99996,Q96QK1,Q9P258,P61221,O14980,Q15334,Q96D46,Q96GA3,P33176,Q92796,P62841,P15311,Q9UIS9,Q13535 16 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.2475977340704626 0.1226278719115584 0.90240178241895 1.0 1.0 8 Q96EB6 1 +Negative regulation of fibroblast apoptotic process 0.5782089552238876 0.1218356727788348 0.9030291615978798 1.0 1.0 2 Q9HCK8 1 +Bleb assembly 0.3097371565113444 0.1216642086167238 0.9031649599933418 1.0 1.0 4 Q4KMQ2,Q9NQW6,Q13464 3 +Macromolecule catabolic process 0.2723378225085625 0.1215981381804335 0.9032172880647602 1.0 1.0 430 Q16740,Q05639,Q00535,Q15369,P17655,Q7Z6Z7,O60502,Q99570,Q96S82,P51784,O75116,P25787,O00487,Q14999,P28066,P49427,Q96RU2,Q13617,P28070,Q9UPR3,Q9UPT9,Q9Y263,Q08J23,P61086,Q05086,O75534,O95376,P14735,O95352,Q9H814,Q6P6C2,Q5VYK3,Q99575,O94822,Q93008,Q15477,Q8N3C0,P67809,Q86W50,Q9Y3I1,Q9Y2V2,Q9P0J0,Q9C0B1,Q5TAX3,Q13310,P25786,P22314,P20618,O96017,P22681,Q9UHG3,P62495,Q14997,P51114,P55036,P48506,P45974,P39748,Q969T7,Q86TB9,Q15386,P40818,O43847,Q6Y7W6,Q6P2E9,Q14790,Q9UL15,Q9UJX4,Q9UIV1,Q9NUJ1,Q9HCE1,Q16186,Q9Y2L1,O95628,O94966,A0AVT1,P62195,Q16763,P62191,Q5T4S7,Q7L5D6,Q96K76,Q92990,Q93034,Q16539,Q14694,Q14258,O60826,Q96KB5,P78559,Q06787,Q96F86,Q13619,O14818,O14980,P68036,Q04323,O43242,O95260,P61289,P35241,P49721,P19784,Q96EB6,P51116,P49407,Q8IXJ6,Q13618,Q6GQQ9,Q5PRF9,O60493,Q9Y5K5,Q9UPY3,Q7L8L6,Q86UV5,Q9NRR5,Q96C86,O75150,P07900,Q9Y5X3,O75792,O75351,Q5VTR2,P28074,Q13501,A4D1P6,A5YKK6,P15311,P27695,P60900,P43686,P53350,P25789,Q15008,Q92900,Q96HR8,Q6PGP7,Q6L8Q7,Q13309,P62081,P08237,P46379,P49720,Q8IWV7,Q9Y5A7,Q9HAU5,Q9ULT8,Q6PKG0,O14965,P05455,Q8IUR7,Q8TAT6,Q9Y5K6,Q15058,P06737,Q13614,Q13200 157 +Cellular response to biotic stimulus 0.2295321155124271 0.12129862699995 0.9034545074849024 1.0 1.0 39 Q8WTV0,P17655,Q9Y263 3 +Trna catabolic process 0.2336032409322341 0.1207489705817226 0.9038898698223006 1.0 1.0 9 Q08J23,Q99575 2 +Vesicle mediated transport between endosomal compartments 0.2377027984729465 0.1207341549911563 0.9039016050992325 1.0 1.0 21 P36507,Q99570,A4D1P6,O75165,O60493,P35241,P28482,Q13614 8 +Midbrain development 0.2345903484811206 0.1206481723589676 0.9039697114723262 1.0 1.0 18 P11413,P27348,Q8IXJ6,O15027,P12277,P14854 6 +Endothelium development 0.2392560326893505 0.1192563479371148 0.9050722659232078 1.0 1.0 26 Q9Y696,Q07157,P21266,Q13464,P35611,O60568,P35241,P67870,P49327,P55196,O75116,P15311,Q9Y4G8 13 +Stress granule disassembly 0.3869811884144487 0.1181740089265167 0.905929783504035 1.0 1.0 3 Q07866,P33176 2 +Negative regulation of smoothened signaling pathway 0.3869811884144448 0.118174008926512 0.9059297835040389 1.0 1.0 3 P17612,P63244 2 +Synaptic vesicle recycling 0.2287928922303899 0.1180972426799234 0.9059906081872268 1.0 1.0 15 Q9Y263,P50570,Q00535,Q13464,O00203,O14617 6 +Regulation of peptidyl tyrosine phosphorylation 0.2377801729324866 0.1169171153908851 0.9069257350528784 1.0 1.0 25 P22681,Q13432,Q06124,Q92796 4 +Positive regulation of response to external stimulus 0.1739280838121732 0.1160943520583033 0.90757776495246 1.0 1.0 60 Q9BUI4,Q9NUD5,Q9UHD2,P28482,O00429,Q15648,P55212,O43318,P30046,P09429,O75179,Q9NW08,Q16512 13 +Positive regulation of cell adhesion 0.1768437383242598 0.116002760568332 0.9076503539510968 1.0 1.0 63 P41440,P00813,P60953,P41240,Q92598,Q13630,Q9HCM4,P09429,Q96AC1,O14617,Q08209,Q13464,Q9HCL2,Q13043,Q14185,P20248,Q14155,Q06124,P00491,Q04206,P50570,P36404,O00203,P46109,Q00534 25 +Negative regulation of proteolysis 0.181589416699014 0.1156121924612418 0.9079598995212654 1.0 1.0 68 O00560,Q00535,Q96K76,Q13177,P68400,Q96KB5,P62829,P78559,P62081,Q15392,Q9NR09,Q04323,P46379,P08238,P19474,O43765,P06744,P19784,Q9C0C9,Q13464,Q9UL15,P61201,Q9Y5K5,P30086,O94966,P04080,P78318 27 +Rna dependent dna biosynthetic process 0.2232057184679385 0.1155477015675932 0.9080110132597112 1.0 1.0 41 P41440,P35251,Q9BUR4,Q96HR8,P08238,P27694,Q96BK5,Q9UPR3,P49368,P50991,P40227,Q8IZH2,P28482,P17987,Q13535,Q99832,P07900,Q9Y4R8,P13010,P48643 20 +Sensory system development 0.2250985380513229 0.1153734628599762 0.9081491120519724 1.0 1.0 40 Q15293,P21359,Q15555,Q8NHU6,A1X283,Q15042,Q15648,P40763,O75569 9 +Proteolysis 0.299001660257524 0.1145627631073511 0.9087916960559332 1.0 1.0 399 Q16740,P55210,Q00535,Q15369,P17655,Q7Z6Z7,Q96S82,Q9Y4P1,P51784,O75116,P25787,O00487,Q14999,P48147,Q15392,P28066,P49427,Q96RU2,Q13617,P28070,Q99627,Q9C0C9,Q9UPT9,Q9Y263,Q86TI2,P61086,P55212,P55786,Q05086,O95376,P14735,Q96BN8,Q5VYK3,O94822,Q93008,Q92688,P52888,Q8N3C0,Q01804,Q9Y3I1,Q9NQW7,Q9P0J0,P25786,P22314,P20618,P22681,Q9UHG3,Q14997,P55036,P48506,P45974,Q8IYS1,Q15386,P40818,O43847,Q14790,Q9UL15,Q9UJX4,P30086,Q16186,O95628,O94966,A0AVT1,Q96FZ2,P62195,Q16763,P62191,Q5T4S7,Q7L5D6,Q96K76,Q92990,Q93034,Q14694,Q14258,O60826,Q96KB5,O14737,P78559,Q06787,Q13619,Q9NR09,O14818,Q9NY33,O14980,P68036,Q04323,O43242,O95260,P61289,P09429,P19474,P40763,P49721,P19784,Q96EB6,Q4J6C6,P49407,P35579,Q8TBC4,Q8IXJ6,Q13618,Q6GQQ9,P20248,P49327,Q9Y5K5,Q86UV5,Q9NRR5,Q92905,O75150,P04080,O75351,Q5VTR2,P28074,Q13501,A4D1P6,O95630,P78318,P60900,P43686,P53350,Q15008,Q13309,P62081,P09960,P46379,P49720,Q96FW1,Q8IWV7,Q9Y5A7,Q9H4A4,Q9ULT8,O14965,P61201,Q8IUR7,Q8TAT6,Q7L5N1,Q9NUQ7,Q9Y5K6,Q15020,Q15058,P42574,P50579,Q13200 143 +Negative regulation of cell cycle process 0.1943508266126191 0.1138542911129136 0.9093533002738772 1.0 1.0 82 Q9Y3I1,Q96K76,P33981,P53350,Q16539,Q92547,Q96DY7,O96017,P50748,Q9Y6G9,Q13619,O60566,Q9NXR7,O43684,O60921,Q96BK5,Q96RU2,O43683,Q9H900,Q6Y7W6,Q15645,Q08J23,P43246,Q06124,Q13564,Q7Z5K2,Q7Z7L1,Q13535,O43264,Q969U7,P14635 31 +Protein localization to golgi apparatus 0.2420739754602214 0.1135018490381452 0.9096326972355492 1.0 1.0 8 Q8TD16,Q9H4A6,Q92538,O14976 4 +Peptide metabolic process 0.2326975448595694 0.1130374039069836 0.9100009012092962 1.0 1.0 393 Q05639,P84098,P62906,P61254,P61247,P50914,P46778,P36578,O75116,P54136,Q86UK7,O00299,O75874,P38935,P14618,P26196,P26639,P62847,P27635,P46199,Q7Z7F7,Q92499,Q9BY44,Q567V2,P31751,Q8TEQ6,P55786,O75534,P13639,P14735,Q14240,P18621,P26640,Q96P11,O94822,P52888,Q8N3C0,P67809,Q86W50,Q9Y285,P49770,P46776,Q9BX40,Q9Y295,Q9P2J5,Q9NQW7,Q9C0B1,Q14232,Q5TAX3,Q9ULC4,Q13310,P29692,P41567,P32969,P62701,P62495,P08708,P51114,P48506,P47897,P42766,P41252,P39019,Q96E11,Q86TB9,Q969T7,Q6Y7W6,Q96I59,Q13144,Q9Y262,Q9UIV1,Q9UET6,P05387,Q9HCE1,P62899,P15880,Q9Y2L1,P05198,P39023,P62266,P46783,P62841,P48507,Q15056,P78417,Q06787,Q7Z478,P62854,P07814,P62269,P61513,P54577,P40763,P51116,P47914,P41214,Q5PRF9,P00374,Q04637,Q92616,Q8NE71,Q8WUX2,Q9NR50,Q9BTE6,Q92905,Q96C86,Q9BQC3,P06730,Q9Y450,O60573,O75821,A5YKK6,P21399,P26641,P27695,P60866,P62750,P62917,P61221,Q92900,Q92600,Q7Z2Z2,Q6L8Q7,Q14152,P11413,P62081,O60841,P09960,O43432,Q96PU8,O15371,O00178,Q9NSD9,P78344,Q13526,Q6PKG0,Q13464,P83731,O43776,P55010,P49591,P63241,Q8IZH2,P62753,Q04206,Q9UQ80,Q9HD33,P49589,P23381,P42574,P28161 151 +I kappab kinase nf kappab signaling 0.1768830875708626 0.1128262833541346 0.9101682802852112 1.0 1.0 64 Q96EB6,P19474,Q92734,Q14790,Q9H8V3,O43318,Q14258,O60826,Q13501,O75116 10 +Rna polymerase ii preinitiation complex assembly 0.2541544744361195 0.1122746225318492 0.9106056628461612 1.0 1.0 7 P09429 1 +Myeloid leukocyte cytokine production 0.2278765821575858 0.1115849735571681 0.9111524869709012 1.0 1.0 9 Q96EB6 1 +Amide biosynthetic process 0.2178562622665844 0.1111883084446641 0.9114670226536474 1.0 1.0 385 Q05639,P84098,P62906,P61254,P61247,P50914,P46778,P36578,O75116,P54136,Q86UK7,P27544,P38935,P14618,P26196,P26639,P62847,P27635,P46199,Q7Z7F7,Q92499,Q9BY44,Q567V2,P31751,Q8TEQ6,O00330,O75534,P13639,Q14240,P18621,P26640,Q96P11,O94822,Q8N3C0,P67809,Q86W50,Q9Y285,P49770,P46776,Q9BX40,Q9Y295,Q9P2J5,Q9C0B1,Q14232,Q5TAX3,Q9ULC4,Q13310,P29692,P41567,P32969,P62701,P62495,P08708,P51114,P48506,P47897,P42766,P41252,P39019,Q96E11,Q86TB9,Q969T7,Q6Y7W6,Q96I59,Q13144,Q9Y262,Q9UIV1,Q9UET6,P05387,Q9HCE1,P62899,P15880,Q9Y2L1,P05198,P39023,P62266,P46783,P62841,P48507,Q15056,Q06787,Q7Z478,P62854,P07814,P08243,P62269,P61513,P54577,P40763,P51116,P47914,P41214,Q5PRF9,P00374,P20248,Q04637,Q92616,Q8NE71,Q8WUX2,Q9NR50,Q9BTE6,Q92905,Q96C86,Q9BQC3,P06730,Q9Y450,O60573,O75821,A5YKK6,P21399,P26641,P60866,P62750,P62917,P61221,Q92900,Q92600,Q7Z2Z2,Q6L8Q7,Q14152,P62081,O60841,O43432,P22059,P53396,Q96PU8,O15371,O00178,Q9NSD9,P78344,Q6PKG0,Q13464,P83731,O43776,P55010,P49591,P63241,Q8IZH2,P62753,Q9UQ80,Q9HD33,P49589,P23381 143 +Positive regulation of cell substrate adhesion 0.2348388391436135 0.1111226144586194 0.9115191160537668 1.0 1.0 27 Q13464,P50570,Q13043,Q9HCM4,P36404,P60953,Q14185,P46109,P20248,Q00534,Q14155,Q96AC1,Q13630 13 +Hindbrain development 0.2304594398038304 0.1108821596972787 0.9117097928539906 1.0 1.0 35 O15020,Q00535,O95456,Q15058,P12277,Q06124,P31939,O95487,P27695 9 +Trna 3 end processing 0.2659892408846342 0.1108102045784827 0.911766853107218 1.0 1.0 6 Q9BQ52,Q96Q11,P05455,Q7L0Y3,Q99714 5 +Regulation of leukocyte migration 0.2343758693125496 0.1103187819530741 0.9121565623327988 1.0 1.0 27 O00401,P00813,O00429,P30046,P09429,P28482 6 +Signal transduction involved in regulation of gene expression 0.5671641791044848 0.1100678738569565 0.9123555462654788 1.0 1.0 2 P09874 1 +Cell cycle process 0.268478723889028 0.1093570927822941 0.9129192645789764 1.0 1.0 377 Q9BV86,Q00535,Q7Z460,P25205,Q99570,Q9BT25,O75116,Q96DY7,P50748,Q14999,Q9H4L7,O60566,Q9UH99,P49427,P11802,O60921,Q96CW5,Q96RU2,Q15648,Q13617,P18858,Q99661,Q9H900,Q9P258,Q9Y570,Q08J23,Q13535,P50570,P43034,P36404,Q14204,Q15398,Q9BPX3,Q9Y3I1,Q9Y295,Q9P0V9,Q9HBM1,Q9H6H4,O95067,Q96Q89,Q7L2J0,O96017,P31350,P23921,O00743,O00401,P39748,Q96BK5,Q08209,P40818,Q6Y7W6,Q15257,Q7Z4H7,Q9BSJ2,Q9UJX4,Q13432,Q9NTJ3,Q16513,Q9UIS9,Q7Z7L1,Q9HC35,O94966,P43487,O75935,Q07864,P42858,Q00534,Q9Y620,Q15021,Q15003,P63172,Q969U7,Q15691,P52732,Q16763,Q96K76,Q6NUK4,Q69YH5,Q9BTE3,Q93034,Q16539,P42771,Q15813,P18074,Q14008,Q13619,Q9NR09,O14980,P68036,O43684,O95905,P61289,P16949,P35241,P19784,Q96EB6,P35579,Q8IXJ6,Q13618,Q15334,Q14203,P20248,Q06124,Q04637,Q13564,Q7Z5K2,Q99986,P06730,Q9H8V3,O95347,O75351,O43264,O75179,O95630,P14635,P15311,P27695,P33981,P53350,P42695,Q15555,Q92900,Q92547,Q9H6S0,Q96DE0,Q13309,Q9Y6G9,Q9NXR7,Q9BY42,P46379,O43683,P33991,Q13526,Q13464,Q15645,P83731,O14965,Q14141,P07437,P30307,P52701,P62753,Q6IBW4,Q15058,O14744 145 +Positive regulation of gastrulation 0.5662686567164249 0.1091618874519187 0.9130740890156824 1.0 1.0 2 O95747 1 +Neuromuscular junction development 0.2392344497607637 0.1090907858035078 0.9131304831352124 1.0 1.0 8 Q12955,Q9NQX3,Q96EY1,Q14203,P46109,Q14696,O15258 7 +Endosome organization 0.2335228662542718 0.1090725422957139 0.9131449530047138 1.0 1.0 26 P40818,Q2M389,Q8WUM4,Q9BTU6,P61020,Q9H9H4,Q99816,O75351,O75165,O60493,Q13501,Q9UN37,Q9Y6D5,Q9H267 14 +Organonitrogen compound catabolic process 0.2369303949136331 0.1084161198291181 0.9136656147296174 1.0 1.0 373 Q16740,Q05639,Q15369,P17655,Q7Z6Z7,O60502,Q9Y3Z3,Q96S82,P51784,P25787,O00487,Q14999,Q9BPU6,P28066,P49427,P33316,Q13126,Q96RU2,Q13617,P28070,Q9UPT9,Q9Y263,P61086,P55786,Q05086,O95376,P14735,O95352,P30519,Q5VYK3,O94822,Q93008,Q8N3C0,P49419,Q9Y3I1,P00813,Q9NQW7,Q9P0J0,P25786,P22314,P20618,O96017,P22681,Q9UHG3,Q14997,P55036,P48506,P45974,Q8IYS1,Q15386,P40818,O43847,O00154,Q14790,Q9UL15,Q9UJX4,Q9NUJ1,Q16186,P00491,O95628,O94966,A0AVT1,P62195,Q16763,P62191,P46926,Q5T4S7,Q7L5D6,Q96K76,Q92990,Q93034,Q14694,Q14258,O60826,Q96KB5,P78559,Q06787,Q8WTV0,Q13619,O14818,O14980,P68036,Q04323,O43242,O95260,P61289,P35241,P49721,P19784,Q96EB6,P49407,Q8IXJ6,Q13618,Q6GQQ9,O60493,Q9Y5K5,Q9UJ70,Q86UV5,Q9NRR5,Q8WUX2,O75150,P07900,Q9Y5X3,O75351,Q5VTR2,P28074,Q13501,A4D1P6,P15311,P60900,P43686,P53004,P53350,Q15008,Q13309,P62081,P09960,P00492,P46379,P49720,Q8IWV7,Q9Y5A7,Q9NRN7,Q9ULT8,O14965,Q8IUR7,Q8TAT6,Q9BY32,Q9Y5K6,Q15058,Q13200 131 +Positive regulation of chromosome separation 0.2119561922775906 0.1074771792497157 0.9144104287632696 1.0 1.0 10 Q9UJX4,Q15398,Q13618 3 +Polyol metabolic process 0.2320714675998934 0.1071271383233842 0.9146881177808346 1.0 1.0 25 Q13572,P51570,Q96PE3,O95861,Q9BW91,P00374,Q00796,Q01968,Q13614 9 +Protein catabolic process 0.3239547217358259 0.1070420434596779 0.914755625487895 1.0 1.0 282 Q16740,Q05639,Q15369,P17655,Q7Z6Z7,O60502,Q96S82,P51784,P25787,O00487,Q14999,P28066,P49427,Q96RU2,Q13617,P28070,Q9UPT9,Q9Y263,P61086,Q05086,O95376,P14735,O95352,Q5VYK3,O94822,Q93008,Q8N3C0,Q9Y3I1,Q9P0J0,P25786,P22314,P20618,O96017,P22681,Q9UHG3,Q14997,P55036,P48506,P45974,Q15386,P40818,O43847,Q14790,Q9UL15,Q9UJX4,Q9NUJ1,Q16186,O95628,O94966,A0AVT1,P62195,Q16763,P62191,Q5T4S7,Q7L5D6,Q96K76,Q92990,Q93034,Q14694,Q14258,O60826,Q96KB5,P78559,Q06787,Q13619,O14818,O14980,P68036,O43242,O95260,Q04323,P61289,P35241,P49721,P19784,Q96EB6,P49407,Q8IXJ6,Q13618,Q6GQQ9,O60493,Q9Y5K5,Q86UV5,Q9NRR5,O75150,P07900,Q9Y5X3,O75351,A4D1P6,P28074,Q5VTR2,Q13501,P15311,P43686,P60900,P53350,Q15008,Q13309,P62081,P46379,P49720,Q8IWV7,Q9Y5A7,Q9ULT8,O14965,Q8IUR7,Q8TAT6,Q9Y5K6,Q15058,Q13200 110 +Endoplasmic reticulum tubular network organization 0.2157979549727608 0.1066875666296791 0.9150368466976806 1.0 1.0 12 Q9H6H4,Q15042 2 +Canonical wnt signaling pathway 0.220708041706631 0.105960058434142 0.9156140424762986 1.0 1.0 40 Q9HCK8,Q04727,Q13526,Q96QK1,Q96K76,Q96BN8,O95071,Q16539,Q13283,Q99471,P40818 11 +Xenobiotic metabolic process 0.2208970959252391 0.1058727421615958 0.9156833210965558 1.0 1.0 15 P07099,P78417,O00170 3 +Regulation of cell death 0.2099137679592909 0.1054126579816278 0.9160483724073664 1.0 1.0 360 Q05639,Q9UMX5,Q00535,P17655,Q96IZ0,Q9BXJ9,Q15392,P13693,P27635,P49427,Q15648,Q96TA1,P78362,Q01105,Q9C0C9,Q9HCL2,P31751,P55212,O00330,Q14155,P17987,O75569,O95352,Q96B36,P51858,Q5VZE5,P50570,P45985,P30154,Q92688,Q9BTT0,Q9Y3I1,P00813,Q9NX46,Q9P0J0,Q99956,Q9UER7,P22392,O96017,P22681,Q99504,P61081,P48506,P26358,P61960,P21359,Q14790,Q15257,Q13144,Q7Z7L1,P15531,P42858,Q969U7,Q96K76,P42771,O14737,Q9NR09,O00429,P61289,P08243,P09429,P31689,P19784,Q96EB6,Q2TAL8,P20248,P49327,Q13564,Q92905,Q96C86,Q9H8V3,Q13501,O95630,P27695,Q92614,Q13309,P11413,P62081,P19174,P46379,Q96AC1,O14965,P63241,P62753,Q9UHD2,Q15058,P42574 87 +Mammary gland morphogenesis 0.2980884109916313 0.1051491929128163 0.9162574253221863 1.0 1.0 4 P07384,Q15648,Q14160 3 +Histone monoubiquitination 0.212339996248334 0.1048488419083487 0.9164957533641966 1.0 1.0 11 Q6W2J9 1 +Protein processing involved in protein targeting to mitochondrion 0.3750373245744998 0.1043770060395565 0.916870169520335 1.0 1.0 3 Q10713,Q99797 2 +Phosphorylation 0.2774101622981635 0.1041211336414199 0.9170732197907324 1.0 1.0 354 O00560,Q05639,O00410,Q00535,Q7Z460,P60953,P52564,Q99570,P85037,Q9UNI6,O75116,O60566,P09972,P14618,P11802,O60921,Q96SB4,Q99627,P78362,Q9BY44,Q9Y4B6,P31751,P61086,Q08AM6,P04183,O75569,Q13535,Q96B36,P51570,Q9BZX2,P45985,P36404,P42356,Q9Y3I1,O95067,Q9UER7,P27708,Q92796,P22392,Q16512,O96017,P22681,O15111,Q13572,Q8TF05,Q99996,P04075,P51114,P47897,P67870,Q969G6,Q92974,Q8TEW0,P49903,P21359,Q8IV63,Q92759,Q13432,Q9UIV1,Q16513,P05198,O95373,P15531,P35790,P42858,Q00534,P46109,Q96JP5,Q01813,P60510,P49761,P41440,Q92990,Q16539,P42771,Q96KB5,Q06787,Q9Y376,Q93100,Q96N67,P63104,Q9NR09,P17858,O43318,P11908,P25440,P51452,P31689,P40763,P51116,P19784,Q96EB6,P49407,Q15126,Q8IXJ6,Q15334,P20248,P49327,Q06124,Q13057,Q04637,Q92616,Q9UJ70,Q13153,Q99986,P07900,Q9H8V3,P00568,O75909,A4D1P6,Q13501,O00764,P14635,P18669,P33981,P53350,P41240,Q8TD19,Q8WUA2,Q92600,Q6PJG6,P08237,P36507,P22059,P08238,O75832,Q96AC1,O00443,O43683,Q9UII4,Q13555,Q13526,Q13464,Q13043,O14965,P60983,P36871,P30307,Q8TBX8,P61201,P28482,P17612,Q14012,Q99741,Q9NYV4,Q9UHD2,Q15058,Q9H2G2,P23381,P12277,P30085,P35080,P42574,P13010,P00558 155 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.2306012158190357 0.1039828379191938 0.9171829680889416 1.0 1.0 28 O00560,P62081,O94966,Q04323,P46379,P68400,Q9UL15,P08238,Q9Y5K5,Q96KB5,P62829,O43765,P78559,P19784 14 +Apical junction assembly 0.229588684966379 0.1038848826840024 0.9172607040612144 1.0 1.0 24 Q13464,O43815,Q8WUM4,Q13177,P36404,Q9H8V3,Q9BTW9,P55196,O75116,Q16513,Q8TEW0,P17612 12 +Cell cell junction organization 0.2034025024380925 0.1036654638263341 0.9174348348187896 1.0 1.0 47 O43815,Q13177,O00192,P60953,P41240,P55196,O75116,Q8WUM4,P35611,Q9BTW9,Q96AC1,P35241,Q8TEW0,Q13464,Q16658,Q9Y490,Q16513,P36404,Q9H8V3,Q9H7S9,P17612,Q8NI35 22 +Regulation of organelle organization 0.2008590347917787 0.1035651824315206 0.91751441943112 1.0 1.0 352 O00560,Q00535,Q9UQB8,P17655,Q7Z460,Q7Z6Z7,P60953,P50395,O75116,Q96DY7,P50748,P47755,Q14999,P27544,O60566,Q9Y6B6,Q9UPR3,Q9H900,P31751,Q14155,P17987,Q13535,P50570,P43034,P36404,Q8TD16,Q14204,Q15398,Q9Y613,Q9BPX3,Q15042,Q9Y696,Q9Y3I1,Q9Y295,Q9H6U6,Q6IBS0,Q96Q89,Q16512,O15020,O00401,Q99996,P35611,P48506,P26358,P39748,Q9BTW9,Q96BK5,Q92974,Q9UJX4,Q9UEY8,Q9NTJ3,O60610,P42858,Q15021,Q15003,Q969U7,Q15691,Q8TC07,Q8NI35,P48643,P47756,Q69YH5,Q9NT62,O14737,P78559,Q5VU43,Q14008,O15344,O43684,O00429,P16949,P35241,P29372,P60981,P19784,P49368,Q8IXJ6,Q13618,Q14203,Q13283,Q9Y5K5,Q7Z5K2,Q9NRR5,Q9NR31,Q13153,Q9H8V3,O95347,O75351,Q13501,O43264,P07737,A5YKK6,P14635,P15311,P27695,P62993,P33981,P53350,Q15555,Q92900,Q96HR8,Q9Y6G9,O60343,Q96QK1,P36507,Q9Y3P9,P22059,O75832,Q96AC1,O43683,Q66K74,Q13526,Q13464,Q15645,Q13045,O14965,P60983,P04350,Q8IX90,P30307,Q8TBX8,Q8IZH2,P28482,Q99741,Q9UJX5,Q9Y5K6,Q9NVG8,O14744,Q00610,P35080,P13010 131 +Vesicle mediated transport 0.1708912920235835 0.1031033617764654 0.9178809369335752 1.0 1.0 350 Q13614,P41440,Q00535,Q9UID3,Q2M389,Q7Z392,P41240,Q14677,Q7Z460,Q9NT62,Q7Z3U7,Q96KP1,Q99570,P20645,Q9UBF2,O60826,Q92614,Q9Y3E0,Q16512,Q06787,Q9Y6D5,Q9UL63,P22681,O15020,Q8WTV0,P57737,O60333,O60343,Q9Y6B6,P36507,O00429,Q96D71,P09429,Q08209,Q4J6C6,Q9C0C9,Q9Y263,Q96T51,O15357,Q9Y2T2,P31751,Q96JB2,Q14185,P24386,Q13432,Q05086,O60493,Q9H269,P28482,O95487,P24390,P53618,Q92538,Q9H4M9,Q92734,Q92905,P48444,Q7Z3T8,P50570,P15531,Q9Y5K6,Q14746,Q8TAG9,P42858,Q9Y5X3,Q9UJY4,O95070,Q13501,O60664,P35080,Q8TD16,Q0VDF9,Q15042,P27695 74 +Cytoskeleton organization 0.2297999523850475 0.1028732684308154 0.9180635538171368 1.0 1.0 349 Q9BV86,Q00535,Q9UQB8,P17655,Q7Z460,Q96IZ0,Q9BT25,Q9BUF5,O75116,P47755,Q14999,Q9UH99,Q96S59,Q96CW5,Q86TU7,Q99661,Q14155,Q96P70,P43034,P36404,Q8TD16,Q14204,Q15398,Q9Y613,Q9BPX3,Q9Y696,Q9Y295,Q9HBM1,Q9H6U6,O95067,Q6IBS0,Q16512,O96017,O15020,O00401,Q99996,P04075,P35611,Q9BTW9,Q92974,Q8TEW0,P21359,Q15257,Q99439,Q7Z4H7,Q16204,Q9BSJ2,Q9UEY8,O43237,Q9UIS9,Q9HC35,P43487,O60610,P42858,Q13885,P63172,Q15691,Q8NI35,P52732,P47756,Q15813,P78559,Q9NZQ3,Q14008,Q96N67,O14980,O15344,P16949,P35241,P29372,P60981,P49407,Q96EB6,P35579,Q13618,Q15334,Q14203,Q9Y490,Q13153,Q03001,Q9H8V3,O75351,O43264,P07737,P14635,P15311,P68371,P62993,P33981,Q15555,Q92614,Q9UL63,P57737,Q96AC1,Q66K74,O15357,O14965,P04350,P07437,P28482,Q9Y5K6,Q15058,P35080 103 +Peptide biosynthetic process 0.260543503613361 0.1024368112690827 0.9184099661714752 1.0 1.0 347 Q05639,P84098,P62906,P61254,P61247,P50914,P46778,P36578,O75116,P54136,Q86UK7,P38935,P14618,P26196,P26639,P62847,P27635,P46199,Q7Z7F7,Q92499,Q9BY44,Q567V2,P31751,Q8TEQ6,O75534,P13639,Q14240,P18621,P26640,Q96P11,O94822,Q8N3C0,P67809,Q86W50,Q9Y285,P49770,P46776,Q9BX40,Q9Y295,Q9P2J5,Q9C0B1,Q14232,Q5TAX3,Q9ULC4,Q13310,P29692,P41567,P32969,P62701,P62495,P08708,P51114,P48506,P47897,P42766,P41252,P39019,Q96E11,Q86TB9,Q969T7,Q6Y7W6,Q96I59,Q13144,Q9Y262,Q9UIV1,Q9UET6,P05387,Q9HCE1,P62899,P15880,Q9Y2L1,P05198,P39023,P62266,P46783,P62841,P48507,Q15056,Q06787,Q7Z478,P62854,P07814,P62269,P61513,P54577,P40763,P51116,P47914,P41214,Q5PRF9,P00374,Q04637,Q92616,Q8NE71,Q8WUX2,Q9NR50,Q9BTE6,Q92905,Q96C86,Q9BQC3,P06730,Q9Y450,O60573,O75821,A5YKK6,P21399,P26641,P60866,P62750,P62917,P61221,Q92900,Q92600,Q7Z2Z2,Q6L8Q7,Q14152,P62081,O60841,O43432,Q96PU8,O15371,O00178,Q9NSD9,P78344,Q6PKG0,Q13464,P83731,O43776,P55010,P49591,P63241,Q8IZH2,P62753,Q9UQ80,Q9HD33,P49589,P23381 137 +Histone phosphorylation 0.2290317722103226 0.1023343031388025 0.9184913282550712 1.0 1.0 25 Q8IV63,Q00535,Q16512,Q99986,O14965,Q9Y4B6,P20248,Q06787 8 +Regulation of cell adhesion 0.2115941049049514 0.1020723935519057 0.9186992132958492 1.0 1.0 106 P41440,P00813,Q92990,Q7Z460,Q9H6U6,P41240,Q96IZ0,Q16539,P42771,O75116,P09429,P51452,Q9BTW9,Q96AC1,Q08209,P21359,Q9HCL2,Q9P258,Q14185,P20248,Q14155,Q06124,P00491,P50570,P36404,O00203,Q15058,P46109,Q00534,P42574 30 +Synaptonemal complex organization 0.2599409450670986 0.1015455990825731 0.9191173617701998 1.0 1.0 6 P46379 1 +Protein lipid complex assembly 0.3720513586145081 0.1011969856010403 0.9193940895776758 1.0 1.0 3 P17612,Q9Y5X1 2 +Positive regulation of canonical wnt signaling pathway 0.2221387395081665 0.1011734765368423 0.9194127513184318 1.0 1.0 18 P40818,Q96K76 2 +Granulocyte chemotaxis 0.2191527284560535 0.1011180820856735 0.919456724187965 1.0 1.0 16 Q92538,O00429 2 +Regulation of fertilization 0.5579104477612014 0.101047254439981 0.9195129484962196 1.0 1.0 2 P35579 1 +Positive regulation of protein metabolic process 0.2463752096011664 0.1010335081153675 0.9195238606321234 1.0 1.0 341 O00560,Q03164,Q00535,P62333,P61254,Q7Z6Z7,P52564,Q96IZ0,O75116,O00487,P14618,Q96S59,Q99627,Q567V2,P31751,P61086,Q05086,O75534,O95376,Q96P70,Q9P265,P13639,P14735,O95352,Q96P11,Q92688,P67809,Q15042,Q9P0J0,Q9UER7,Q92796,Q16512,O96017,Q99996,P62701,Q14997,P51114,P48506,P26358,P45974,P67870,Q92974,Q8IV63,O43847,Q14790,Q15257,Q13144,Q13432,Q16186,P15880,P18615,P46109,Q96JP5,P62195,Q16763,P62191,P41440,Q69YH5,O60826,O14737,Q06787,Q9Y376,Q7Z478,Q96N67,Q9UBT2,P68036,O43318,P61289,P09429,P35241,P40763,P51116,P49407,Q96EB6,P35579,Q8IXJ6,Q13618,Q15334,P20248,P49327,Q06124,Q04637,Q13153,O75150,P07900,Q9H8V3,O75909,Q5VTR2,Q13501,P14635,P15311,P43686,P33981,P53350,P41240,Q969T9,Q92600,Q6PJG6,Q13309,Q96QK1,P36507,P46379,P22059,P08238,O75832,O15371,Q96AC1,Q99873,Q9Y5A7,P78344,Q9ULT8,Q13526,Q6PKG0,Q13043,O14965,P63241,P28482,Q14012,Q99741,Q04206,Q9UHD2,Q9BW61,Q15020,Q15058,Q14738,P35080,P42574,P13010 128 +Inner cell mass cell differentiation 0.5576119402985149 0.1007687259809991 0.919734053490006 1.0 1.0 2 Q6PD62 1 +Regulation of protein modification process 0.2412780943797928 0.1001077095263089 0.9202588147649122 1.0 1.0 337 Q03164,P41440,P60866,P31946,Q00535,Q92990,Q69YH5,P41240,O95067,P42771,Q8WUA2,Q9UER7,Q92796,O75116,Q16512,Q96DY7,Q06787,Q13309,P22681,P11413,P62081,Q99996,Q96N67,Q9UBT2,P68036,Q04323,P36507,P22059,O43318,O60921,P26358,Q96FW1,P67870,P19474,Q96AC1,P31689,Q96EB6,Q01105,P21359,Q9UII4,Q9Y263,Q15257,O95071,P31751,Q13432,Q05086,P20248,P30307,P49327,Q9P265,Q06124,P28482,O95352,Q96B36,P35080,Q6W2J9,Q9UHD2,Q9H8V3,P18615,Q15020,Q15058,P42858,Q14738,Q5VTR2,Q13501,Q96JP5,P42574,P14635,Q15042,Q16763,Q01804 71 +Ovulation cycle 0.2197225270610407 0.0999427080876955 0.9203898099172898 1.0 1.0 9 Q96EB6 1 +Rna stabilization 0.2278354708291641 0.0997218521119262 0.9205651515396884 1.0 1.0 29 Q9H814,Q6PKG0,Q08J23,Q96HR8,P67809,Q86W50 6 +Modulation by host of viral genome replication 0.2457718964347449 0.0996889906604725 0.9205912411808256 1.0 1.0 7 Q06787 1 +Protein localization to organelle 0.1497005610160958 0.0989480575976078 0.9211795116523886 1.0 1.0 332 O00629,O00170,Q00535,Q9P0J0,Q9Y5K8,Q9BUR4,Q7Z6Z7,Q15555,Q99570,P20645,Q96Q89,O14737,O75116,Q7L2J0,Q96DY7,P61970,P78559,Q3SYG4,P50748,Q9UH99,P68036,O00429,P46379,Q92499,P61960,Q96AC1,P29372,P31689,Q15648,Q08209,P40763,P19784,P21359,O15397,Q9H900,Q9P258,O14965,Q9Y2T2,O95071,Q96JB2,O60830,Q9Y5L0,P55786,P05455,P55060,O95376,Q96P70,P17987,P60059,Q7Z4Q2,Q13535,Q7Z5K2,P24390,P51858,Q92538,Q9H4M9,P36404,Q7Z3T8,Q9H8V3,Q9Y5K6,Q15785,Q96D46,P20290,Q13501,P67809,Q15042 66 +Process utilizing autophagic mechanism 0.2524384419552128 0.0987596929614439 0.9213290723388468 1.0 1.0 160 Q05639,Q00535,Q9UID3,Q8NCE2,Q7Z6Z7,Q9Y5K8,Q9NT62,P85037,Q9Y4P1,P27544,Q9Y487,O00429,O43318,Q15382,P61960,P09429,P19474,P40763,P19784,Q96EB6,Q9Y263,Q66K74,Q6PKG0,P50851,Q9H269,O95352,Q9UHD2,P42858,Q9Y5X3,Q13501,P42574,Q15042,P27695 33 +Outflow tract morphogenesis 0.2183519728598557 0.0981431893691571 0.9218185928865594 1.0 1.0 9 P46109,P60953,O95487 3 +Vacuolar localization 0.2167463460771392 0.0979192546260608 0.9219964104800128 1.0 1.0 16 P33176,Q8NCA5,Q9H0B6,P22681 4 +Protein localization to chromosome telomeric region 0.2209831246162352 0.097840736087693 0.922058759824262 1.0 1.0 19 P49368,Q99832,P50991,Q9BUR4,P40227,Q96BK5,P13010,P17987,P48643,Q13535 10 +Regulation of mitotic spindle assembly 0.206171480215673 0.096840706585178 0.9228528966564482 1.0 1.0 11 Q9Y295,Q8WUM4,P53350,P0DMV9,O75351 5 +Germ cell development 0.2101171001563067 0.09668639594011 0.922975443677341 1.0 1.0 43 Q15645,O14965,Q14997,Q08J23,Q8NHU6,Q5TAX3,Q96PU8,P62753,Q9H6S0,Q96SB4 10 +Mitotic cell cycle 0.2881895145915601 0.096525682780872 0.9231030772492756 1.0 1.0 318 O00560,Q00535,P61254,Q7Z460,P25205,P60953,P46940,Q9BUF5,Q9GZZ1,O75116,Q96DY7,P50748,Q14999,Q13616,P35244,O60566,Q9UH99,P49427,P11802,O60921,Q96CW5,Q13617,P18858,Q99661,Q9UPT9,Q9H900,Q9P258,Q9Y570,P50570,P43034,Q14204,Q15398,Q9BPX3,Q9Y3I1,Q9Y295,Q9HBM1,Q9H6H4,O95067,Q96Q89,Q7L2J0,O96017,O75717,P31350,P23921,O00743,Q9BTW9,Q96BK5,Q08209,P40818,Q6Y7W6,Q15257,Q9BSJ2,Q9UJX4,Q13432,Q9NTJ3,Q16513,Q7Z7L1,Q9HC35,P43487,O75935,Q07864,P42858,Q00534,Q15021,Q15003,Q13885,P63172,Q969U7,P52732,Q16763,Q96K76,Q6NUK4,Q69YH5,Q93034,P42771,Q15813,P18074,Q96KB5,Q14166,Q14008,Q13619,O43684,O95905,P61289,P08243,P16949,P51452,P35241,Q96EB6,Q8TBC4,Q8IXJ6,Q13618,Q14203,P20248,Q06124,Q04637,Q13564,Q7Z5K2,Q92538,O75150,Q99986,P06730,Q9H8V3,O95347,O75351,Q5VTR2,O43264,O75179,O95630,P14635,P27695,P68371,P33981,P53350,P42695,Q92547,Q9H6S0,Q13309,Q9Y6G9,Q9NXR7,Q9BY42,O43683,P33991,Q13526,Q13464,Q15645,P83731,O14965,Q14141,P04350,P43246,P07437,Q8IX90,P30307,P62753,Q29RF7,Q6IBW4,Q99741,Q9UJX5,Q15058,O14744,Q00610,O95239 143 +Regulation of neutrophil migration 0.2302631578947392 0.0963719158250187 0.9232251962082862 1.0 1.0 8 P84095,Q07021,O00429,Q8NHP6,O94813,P63000,Q00013 7 +Regulation of catabolic process 0.2189480014337562 0.0959491245611392 0.9235609787685486 1.0 1.0 319 Q05639,Q00535,Q7Z6Z7,Q99570,P85037,O75116,O00487,P27544,O75874,P11802,Q15382,Q08J23,P31751,P61086,Q05086,O75534,O95376,P14735,O95352,Q9H814,P36404,Q6P6C2,P67809,Q86W50,Q15042,Q9Y3I1,Q9Y2V2,Q9P0J0,Q9Y5K8,Q9C0B1,Q5TAX3,Q13310,O96017,Q9Y487,P51114,P48506,P45974,Q969T7,Q86TB9,P40818,O43847,Q6Y7W6,Q9UL15,Q9UIV1,Q9HCE1,Q9Y2L1,O94966,P42858,P62195,P62191,Q92990,Q16539,Q14694,O60826,Q96KB5,P78559,Q06787,Q8WTV0,O14980,O43242,Q04323,O00429,O43318,P61289,P09429,P19474,P35241,P40763,P51116,P19784,Q96EB6,Q8IXJ6,Q5PRF9,O60493,Q04637,Q9Y5K5,Q7L8L6,Q9NRR5,Q96C86,O75150,P07900,P06730,Q9Y5X3,A4D1P6,A5YKK6,P15311,P18669,P27695,P43686,P53350,Q93050,Q92900,Q96HR8,Q6L8Q7,P62081,Q96QK1,P46379,O43432,P08238,O75832,O00178,Q9Y5A7,O00443,P78344,Q9ULT8,Q13526,Q6PKG0,O14965,Q9UHD2,P42574,Q13614,Q13200 112 +Negative regulation of rna catabolic process 0.2230240571185229 0.095911385786508 0.9235909517216307 1.0 1.0 34 Q9H814,Q6PKG0,Q08J23,Q96HR8,P67809,Q06787,Q86W50 7 +Cartilage development 0.2114730309789241 0.0957064395956956 0.9237537263233964 1.0 1.0 14 O95747,Q92896,P35222,Q96HY6,Q16539,O75844,P20248,P27361,Q9C0E8,Q06124,P50454,P04818 12 +Epidermis development 0.1803608624819905 0.0951653828502467 0.9241834656432532 1.0 1.0 53 Q9Y696,P21359,P67809,P43034,P42574,O60568,Q08J23,P18074,P22392,O75116,Q15648,O95487 12 +Embryo development ending in birth or egg hatching 0.240082188099348 0.0948904138484561 0.924401870801962 1.0 1.0 146 P62993,P00813,P43686,O43772,P17655,Q92990,O95067,P18074,Q96Q89,Q9H0G5,P31350,Q13572,Q9HCK8,P62081,Q13619,Q9NR09,O60921,P25440,Q8IWS0,Q96AY3,Q15648,Q99873,P21359,P35579,Q9UPT9,Q9ULT8,Q14790,Q13618,Q08J23,Q6GQQ9,P20248,P61201,P28482,O95487,P07737,Q15293,P11586,P26572,P42574,Q6W2J9,O60568,Q9NPQ8,Q01968,P67809,A5YKK6,P14635,Q9BRT9,P20290 48 +Positive regulation of molecular function 0.2395521828458599 0.0943487963306595 0.9248320888918986 1.0 1.0 312 Q05639,Q03164,Q00535,Q99570,Q9UNI6,O75116,O00487,Q96TA1,Q99627,Q9Y263,Q9P258,P31751,O00330,Q08AM6,Q14155,P14735,P17987,P50570,Q96D46,Q92688,Q9BRT9,Q15042,Q9P2J5,Q9P0J0,Q9H6U6,Q9BUR4,Q9UER7,Q92796,Q16512,P35754,O15111,Q99996,P35611,Q14997,Q96BK5,Q969G6,Q92974,Q08209,Q8WXX5,P21359,Q14790,Q15257,Q86X10,Q13432,P15531,P42858,Q96JP5,Q8TC07,Q16763,P41440,P18074,Q14258,O14737,P78417,Q06787,Q8WTV0,Q96N67,P68036,O43318,P61289,P09429,P16949,P19474,P40763,Q96EB6,P00374,P20248,P20585,P49327,Q92616,Q92905,Q9H8V3,P14635,P27695,P31946,P60900,P41240,Q15555,Q96HR8,O60343,P36507,Q96AC1,P52701,P28482,Q15058,P35080,P28161 87 +Positive regulation of sodium ion transmembrane transporter activity 0.2414089404053211 0.0937315586635846 0.9253224004401002 1.0 1.0 7 P35754 1 +Negative regulation of extrinsic apoptotic signaling pathway 0.2224512296934272 0.0936417606177632 0.9253937351672424 1.0 1.0 24 P42858,Q99504,Q9NR09 3 +Lymphocyte mediated immunity 0.2185322893021588 0.0936013250392567 0.925425857008256 1.0 1.0 37 P36915,P00492,P07437,O43318,P09429,Q96FZ2,Q9UQ84 7 +Carbohydrate homeostasis 0.2038550212225515 0.0933853917718753 0.9255973954778643 1.0 1.0 45 Q96EB6,P08237,P22059,P85037,P40763,Q06124,P62753,Q08209 8 +Regulation of dna helicase activity 0.3638787276370627 0.0930278256886827 0.9258814553687312 1.0 1.0 3 P49736 1 +Cell part morphogenesis 0.2253902016470756 0.0930059349061061 0.9258988462888652 1.0 1.0 128 P41440,Q00535,Q9UQB8,Q6IBS0,Q96Q89,P78559,Q16512,Q14999,Q9BPU6,Q96N67,P00492,O00429,P16949,Q96TA1,Q08209,Q9Y263,Q8N0X7,Q66K74,O14965,Q05086,O60678,Q14155,Q9P265,Q06124,P50570,P43034,Q93008 27 +Dna metabolic process 0.2051330588046284 0.0929493336655346 0.9259438127601805 1.0 1.0 306 P53999,Q03164,P41440,Q9NX46,Q96K76,P27695,P54277,P25205,Q7Z6Z7,Q9Y3Z3,Q9BUR4,Q9C0B1,P18074,Q92547,Q92614,Q96HR8,O96017,Q9UQ84,P49005,O00487,P23921,P27544,Q9H4L7,P35244,P38935,Q99504,Q14997,P49427,P46063,Q92499,O60921,P26358,P09429,Q7Z4V5,Q96FW1,Q96RU2,P29372,Q96TA1,Q9UPR3,P18858,P49642,P78362,P28340,Q9UBD5,Q96EB6,Q15645,Q9Y4B6,Q92759,O95071,P20585,P04183,P52701,P28482,P17987,Q13535,Q7Z7L1,Q86WJ1,Q96T76,Q9NUW8,P15531,Q07864,Q93008,O14744,Q9Y620,Q8N3C0,Q96FZ2,Q9BRT9,Q01804 68 +Positive regulation of protein modification process 0.2735995916641037 0.0927983487989092 0.9260637628192804 1.0 1.0 200 Q03164,P41440,Q00535,Q69YH5,P41240,Q9UER7,Q92796,O75116,Q16512,Q06787,Q13309,Q99996,Q96N67,Q9UBT2,P68036,P36507,P22059,O43318,P26358,P67870,Q96AC1,Q96EB6,Q15257,P31751,Q13432,Q05086,P20248,P49327,Q9P265,Q06124,P28482,O95352,P35080,Q9UHD2,Q9H8V3,P18615,Q15020,Q15058,Q14738,Q5VTR2,Q13501,Q96JP5,P14635,Q15042,Q16763 45 +Cellular response to toxic substance 0.2225397258338535 0.0924884673154581 0.92630995369578 1.0 1.0 31 P78417,Q9BYN0,P35754,P27544 4 +Regulation of cell cell adhesion 0.1792037679432704 0.0923162723315672 0.926446760126076 1.0 1.0 53 P41440,P00813,P00491,Q9HCL2,Q92990,P41240,O00203,Q96IZ0,Q16539,P09429,P51452,Q06124,P42574 13 +Regulation of cell cycle 0.2242745532230687 0.0918010814639354 0.926856084808289 1.0 1.0 301 O00560,O00410,Q00535,P61254,P60953,P52564,Q99570,O75116,Q96DY7,P50748,Q14999,O00299,Q15392,O60566,P35244,P11802,O60921,Q15382,Q96RU2,Q15648,P78362,Q9H900,Q9UPT9,Q9P258,Q08J23,P31751,Q13535,P43034,Q14204,Q15398,Q9Y3I1,Q9Y295,O95067,Q96Q89,Q7L2J0,O96017,P31350,P23921,P39748,Q96BK5,Q6Y7W6,Q9UJX4,Q16513,Q7Z7L1,O95373,O94966,P43487,Q00534,Q969U7,P52732,Q96K76,Q69YH5,Q16539,P42771,P18074,Q14166,Q13619,Q9NR09,O14980,O43684,O95905,P61289,P08243,P51452,P19474,P35241,P40763,P19784,Q96EB6,Q8TBC4,Q8IXJ6,Q13618,Q14203,P20248,Q06124,Q04637,Q13564,Q9Y5K5,Q7Z5K2,Q92538,Q92905,O75150,P06730,Q9H8V3,O75909,O75351,Q5VTR2,O43264,O75179,P14635,P27695,P33981,P53350,Q92547,Q9H6S0,Q96DE0,Q13309,Q9Y6G9,Q9NXR7,P08238,O75832,O15355,O43683,P78344,Q9UII4,Q13526,Q15645,O14965,P43246,P30307,Q99741,Q9Y4A5,Q9UJX5,P42574,Q9NYV4,Q15058,O14744,Q00610,P17612 119 +Rho protein signal transduction 0.2194210481626995 0.0906249103508865 0.9277906377773943 1.0 1.0 23 O75116,P41440 2 +Cytokine production 0.2089289623349456 0.0906239708330067 0.9277913843322534 1.0 1.0 109 P41440,Q92990,P17655,Q9NUD5,P41240,O75116,Q9NW08,Q9Y6D5,Q9BUI4,O14802,Q92499,O43318,P30046,P09429,P19474,P40763,Q96EB6,Q14790,Q8NCF5,Q06124,Q8TAT6,Q9UHD2,Q9Y5K6 23 +Regulation of intracellular signal transduction 0.2354894515200031 0.0904364350925715 0.9279404042882704 1.0 1.0 295 P41440,P00813,Q9UMX5,P60866,O00170,Q96K76,Q9P0J0,Q9NUD5,P41240,Q99956,Q15555,Q14258,O60826,O75116,Q16512,Q9Y6D5,Q14152,P22681,P62081,P36507,P49427,O00429,O43318,P30046,Q15382,P09429,P16949,P19474,P29372,P31689,Q8IWV7,Q96AC1,Q99873,Q96EB6,P21359,Q14790,O14965,Q86X10,P63241,Q05086,P20248,Q96P70,Q06124,P49327,P28482,P30086,Q8TAT6,O75569,Q13535,Q96B36,Q92538,Q92734,Q92905,Q9UHD2,Q9H8V3,P18615,Q9Y5K6,Q15058,P42858,Q13501,O75179,O95630,P14635 63 +Response to endogenous stimulus 0.1820063862136707 0.0904119101890699 0.9279598924940852 1.0 1.0 295 P49770,P55210,Q9P2J5,Q00535,Q9UQB8,P17655,Q9H6U6,P41240,Q9UER7,Q14258,O14737,O75116,Q16512,Q13309,P22681,Q15392,O75874,Q99996,O60343,P14618,P09960,P19174,P68036,P11802,O43318,P26358,P61960,P67870,Q8IWV7,Q96AC1,Q15648,P40763,P40818,Q96EB6,Q9C0C9,Q8N0X7,Q6PKG0,O15357,O95071,P31751,Q13144,P55212,O00330,Q05086,P20248,P07741,Q00796,Q06124,P14735,O43237,P43490,P28482,Q96T76,P50570,Q9H4M9,Q9NUQ7,Q9Y5X3,Q93008,O14744,P42574,P28161,P27695 62 +Myeloid leukocyte differentiation 0.2205293757458478 0.0901845528628864 0.9281405593325918 1.0 1.0 32 Q96EB6,P21359,Q13619,Q14790,P43034,O00203,Q16539,Q00534,O00625,P49327,Q15648 11 +Metencephalon development 0.2208209357036175 0.0900394189823914 0.92825589020996 1.0 1.0 31 O15020,Q00535,Q15058,P12277,Q06124,P31939,O95487,P27695 8 +Positive regulation of i kappab kinase nf kappab signaling 0.1913969400575727 0.0900323929757598 0.9282614734759772 1.0 1.0 49 Q92734,Q14790,Q9UHD2,Q9H8V3,Q92499,O43318,Q14258,P29692,O60826,Q9Y3E0,O75179,P19474 12 +Cell proliferation involved in metanephros development 0.5453731343283652 0.0900019326016869 0.9282856790691838 1.0 1.0 2 O95747 1 +Negative regulation of kidney development 0.5453731343283652 0.0900019326016869 0.9282856790691838 1.0 1.0 2 O95747 1 +Mesenchymal cell differentiation involved in kidney development 0.5453731343283652 0.0900019326016869 0.9282856790691838 1.0 1.0 2 O95747 1 +Cell proliferation involved in kidney development 0.5453731343283652 0.0900019326016869 0.9282856790691838 1.0 1.0 2 O95747 1 +Metanephric mesenchyme development 0.5453731343283652 0.0900019326016869 0.9282856790691838 1.0 1.0 2 O95747 1 +Kidney mesenchyme development 0.5453731343283652 0.0900019326016869 0.9282856790691838 1.0 1.0 2 O95747 1 +Metanephric mesenchymal cell differentiation 0.5453731343283652 0.0900019326016869 0.9282856790691838 1.0 1.0 2 O95747 1 +Tissue morphogenesis 0.1800950850976769 0.0898590127056298 0.9283992524559516 1.0 1.0 76 P62993,Q9Y696,Q92990,Q7Z460,P60953,Q96Q89,Q92796,Q16512,P62081,Q9HCM4,Q13418,P25440,P67870,Q96AC1,Q15648,Q9ULT8,Q13043,O00330,P20248,O95487,P11586,Q13153,P43034,P42574,O60568,P17612,P07737,P15311 28 +Response to oxygen containing compound 0.1779267845391242 0.0890282972069013 0.9290594214878902 1.0 1.0 289 P49770,Q9P2J5,Q00535,Q9NX46,Q9UQB8,Q9P0J0,P17655,P41240,Q96IZ0,Q14232,Q6IBS0,Q14258,O75116,O96017,O00487,P27544,P22681,Q8WTV0,P11413,Q99996,O60343,P14618,P09960,P11802,Q13126,P17858,P22059,P26358,P09429,Q8IWV7,Q15648,Q08209,P40763,P40818,Q96EB6,Q9Y263,Q9HCL2,Q14790,Q15126,Q6PKG0,O15357,Q99707,P31751,Q13144,O00330,Q05086,P00374,P07741,P20248,Q06124,P14735,P28482,P43490,P50570,Q96C86,Q9GZT9,Q9H8V3,Q9Y5X3,O14744,P42574,P27695 61 +Cellular response to xenobiotic stimulus 0.2199178929570933 0.088790879492176 0.9292481061725496 1.0 1.0 31 P07099,P11172,O00170,P27544 4 +Skin development 0.2036945919810237 0.0887619146337607 0.92927112589484 1.0 1.0 44 Q9Y696,P21359,Q15392,P42574,Q08J23,P18074,P16949,O75116,Q15648 9 +Protein adp ribosylation 0.1989477734345602 0.088652000942284 0.9293584799639574 1.0 1.0 11 Q96EB6,Q9UGN5,Q8IXJ6,P09874,P23381,Q7Z2W4 6 +Negative regulation of arp2 3 complex mediated actin nucleation 0.5435820895522465 0.0885311871255224 0.9294544979057436 1.0 1.0 2 P60983 1 +Tissue development 0.167126343353519 0.0883365388854195 0.9296091986246084 1.0 1.0 286 P11310,P41440,P00813,Q00535,Q92990,Q7Z460,Q8NHU6,P18074,Q9Y4P1,Q96Q89,O75116,Q92796,Q16512,Q14999,Q13572,P62081,Q15392,P11413,P09972,P13693,P09960,P11802,Q15382,P67870,Q96AC1,Q15648,Q99873,Q96TA1,Q08209,Q96EB6,P21359,Q9ULT8,Q8N0X7,Q08J23,P31751,P55212,O00330,P20248,P07437,A1X283,P49327,Q06124,P61201,P28482,P43490,O95487,Q6W2J9,Q00534,P42574,P67809 50 +Positive regulation of viral genome replication 0.2130521809876942 0.0880656779595027 0.9298244753783816 1.0 1.0 19 P78362,Q6PKG0,Q9UIV1,Q9UNP9,Q96SB4,Q16513 6 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.2047095142455221 0.0879554594716023 0.9299120770750564 1.0 1.0 14 Q96EB6,Q9Y3F4,P50570,Q8N0X7,Q9UPN9 5 +Endothelial cell migration 0.2136868654769898 0.0879003601170504 0.929955870381752 1.0 1.0 38 Q96EB6,Q8WTV0,P21359,P09429,P67870,O75116 6 +Intracellular estrogen receptor signaling pathway 0.217103199813353 0.0878029822758782 0.930033267408852 1.0 1.0 23 Q13153,Q9NUQ7,Q969T9,Q92600,P61960,Q15648,Q16512,Q86X55,Q13309,A5YKK6 10 +Positive regulation of dna repair 0.2174425531935573 0.0874853012298469 0.9302857685517234 1.0 1.0 34 Q99504,Q9BUR4,P09429,Q7Z4V5 4 +Negative regulation of protein metabolic process 0.1759195835287798 0.0871837592435111 0.9305254484433436 1.0 1.0 281 Q00535,O75116,Q15392,O60566,P26196,Q01105,Q9C0C9,Q9Y263,O60678,O75534,Q96B36,Q32P28,P67809,Q86W50,Q9Y3I1,Q9C0B1,Q5TAX3,Q16512,P22681,P51114,P48506,P47897,P26358,Q96BK5,Q969T7,Q86TB9,Q8TEW0,P21359,Q6Y7W6,Q15257,Q9UL15,Q9UIV1,Q9HCE1,P30086,Q9Y2L1,P05198,O95373,O94966,Q6W2J9,P46109,P62841,P60510,Q96K76,Q92990,P42771,Q96KB5,P78559,Q06787,Q9NR09,O43684,Q04323,P07814,P51452,P19474,P31689,P40763,P51116,P19784,Q96EB6,P49407,Q8IXJ6,Q5PRF9,P00374,O60493,Q99471,Q04637,Q9Y5K5,Q96C86,P06730,P04080,O60573,Q13501,A5YKK6,P27695,P78318,P60866,P31946,P53350,Q92900,Q92600,P11413,P62081,P46379,Q96FW1,Q6PKG0,O95071,P61201,P42574 88 +Response to toxic substance 0.186838592385861 0.0868952830189692 0.9307547489447964 1.0 1.0 50 Q9BYN0,P07099,P00374,P78417,P35754,P27544 6 +Mitotic g2 m transition checkpoint 0.2104179105802889 0.0866994888699126 0.9309103827118436 1.0 1.0 18 Q13564,O60921 2 +Gland morphogenesis 0.1967049010747459 0.0863577731871967 0.9311820135942668 1.0 1.0 11 Q13618,P60953,P07384,Q15648,Q15418,P15311 6 +Neurogenesis 0.2094329499698176 0.0862655659343618 0.9312553108072764 1.0 1.0 277 Q00535,Q9UQB8,Q14999,O60701,Q9BPU6,P26196,Q15382,Q15648,Q96TA1,Q9BW83,Q9Y263,Q99707,P31751,Q05086,O60678,Q9P265,O95487,P50570,Q9H4M9,P43034,Q96P11,Q93008,Q32P28,P49770,Q9Y3I1,Q14232,Q6IBS0,Q96Q89,Q16512,O00401,Q9BTW9,Q92974,Q08209,Q8TEW0,P21359,Q6Y7W6,Q8N0X7,Q13144,Q9UL15,Q9BSJ2,Q9HCE1,Q9UIS9,A0AVT1,P46109,Q00534,Q9UBB6,Q13885,P63172,P41440,P18074,P78559,Q06787,Q9NZQ3,Q96N67,P63104,P33176,P16949,P09429,P40763,Q8IXJ6,Q15334,P00374,O60493,Q06124,Q04637,Q9UPY3,Q9NR50,Q13153,P07900,Q9H8V3,P27695,P41240,Q15555,P00492,Q99873,Q66K74,P10589,O14965,P61201,P28482,O14744,P42574,Q13614 83 +Polyamine metabolic process 0.3562257390265694 0.0860681268350301 0.931412260678377 1.0 1.0 3 P52788,P19623 2 +Peptidyl amino acid modification 0.2326018031782663 0.0858526581508695 0.9315835458148808 1.0 1.0 275 P49761,Q03164,Q9BV86,Q00535,O00170,Q7Z460,P41240,Q8WUA2,Q9BXJ9,P27708,Q92796,O75116,P22392,Q16512,O96017,Q9Y237,Q14CX7,P22681,O15111,Q99996,Q96N67,Q9UBT2,P36507,P46379,O14929,O43318,P26358,Q96BP3,P22059,P67870,Q96AY3,Q86TU7,Q92974,Q99873,Q8TEW0,P19784,P78362,Q01105,Q8IV63,Q9UPT9,Q96EB6,Q15257,O14965,Q9Y4B6,Q9H2H8,P31751,P61086,Q13432,P08397,O60678,Q9UIV1,Q9P265,Q06124,P28482,Q13535,P26572,Q5VZE5,P45985,Q99986,Q6W2J9,Q9GZT9,Q9BQC3,P18615,Q9UHD2,O14744,P50579,Q32P28,P35080,P13674 69 +Postsynaptic specialization organization 0.3559271424305709 0.0858097483653558 0.9316176569901132 1.0 1.0 3 Q12959,Q15334 2 +Mitotic cell cycle process 0.27130648451973 0.0856574019332418 0.931738765946883 1.0 1.0 267 Q00535,P61254,Q7Z460,P25205,P60953,Q9GZZ1,O75116,Q96DY7,P50748,Q14999,Q13616,O60566,Q9UH99,P49427,P11802,O60921,Q13617,P18858,Q99661,Q9H900,Q9P258,Q9Y570,P50570,P43034,Q14204,Q15398,Q9BPX3,Q9Y3I1,Q9Y295,Q9HBM1,Q9H6H4,O95067,Q96Q89,Q7L2J0,O96017,P31350,P23921,O00743,Q96BK5,Q08209,P40818,Q6Y7W6,Q15257,Q9UJX4,Q13432,Q9NTJ3,Q7Z7L1,Q9HC35,P43487,Q07864,P42858,Q00534,Q15021,Q15003,P63172,Q969U7,P52732,Q16763,Q96K76,Q6NUK4,Q69YH5,Q93034,P42771,Q15813,P18074,Q14008,Q13619,O43684,O95905,P61289,P16949,P35241,Q8IXJ6,Q13618,Q14203,P20248,Q04637,Q13564,Q99986,P06730,Q9H8V3,O95347,O75351,O43264,O75179,O95630,P14635,P27695,P33981,P53350,P42695,Q92547,Q13309,Q9Y6G9,Q9NXR7,Q9BY42,O43683,P33991,Q13526,Q13464,Q15645,P83731,O14965,Q14141,P43246,P30307,P62753,Q29RF7,Q6IBW4,Q99741,Q9UJX5,Q15058,O14744,Q00610,O95239 115 +Ribose phosphate metabolic process 0.2354979733534602 0.085541941003574 0.931830553545427 1.0 1.0 148 P00813,P11172,Q86TX2,P85037,P27708,P22392,O60256,P11413,Q06203,P30520,P04075,P09972,P49915,P14618,P08237,P00492,P17858,P53396,Q96IU4,P31939,P40763,Q9P2T1,O00154,Q9HCL2,Q15126,Q9UKG9,O00330,P20839,Q01433,P07741,Q13057,P51570,Q9BY32,Q9BZX2,P36404,P15531,Q9UKK9,P53602,P17812,Q9NVE7,P06737,P30566,P18669,O15067 44 +Positive regulation of nf kappab transcription factor activity 0.2169638073007327 0.0853115577607626 0.9320137032682304 1.0 1.0 32 P41440,O43318,Q14258,P19474,P40763 5 +Peptidyl lysine modification 0.2036597448760722 0.0852166292463076 0.9320891704431988 1.0 1.0 106 Q01105,Q03164,Q9UPT9,Q6W2J9,Q9UBT2,P18615,O14929,O43318,P26358,Q9P265,Q86TU7 11 +Regulation of cellular macromolecule biosynthetic process 0.1866469763381622 0.0846483075551587 0.9325409929813178 1.0 1.0 270 Q96IZ0,O75116,P27544,P14618,P26196,P27635,P46199,Q92499,Q96TA1,Q9UPR3,Q9BY44,Q9UBD5,Q567V2,P31751,Q8TEQ6,O75534,P13639,Q14240,P17987,Q13535,Q99805,Q96P11,P67809,Q86W50,Q9BRT9,Q15042,P49770,Q9BX40,Q9BUR4,Q9C0B1,Q5TAX3,P41567,P62701,P62495,P51114,Q96BK5,Q969T7,Q86TB9,Q6Y7W6,Q13144,Q9UIV1,Q9HCE1,Q7Z7L1,Q9Y2L1,P05198,P48643,Q15056,Q06787,Q7Z478,P07814,P40763,P51116,P49368,Q5PRF9,P00374,P20248,Q04637,Q9Y5K5,Q92616,Q7Z5K2,Q96C86,P07900,P06730,Q9BQC3,Q9Y450,O60573,O75179,A5YKK6,P21399,P61221,Q92900,Q92600,Q96HR8,Q6L8Q7,O60841,O43432,P08238,Q96PU8,O15371,Q99873,P78344,Q6PKG0,Q13464,P55010,P63241,Q8IZH2,P28482,Q29RF7,Q99741 89 +Positive regulation of myelination 0.3545197281239532 0.0846049922508012 0.9325754300593698 1.0 1.0 3 Q8TEW0 1 +Microtubule based process 0.2755928679692261 0.0844453848064448 0.9327023242659584 1.0 1.0 231 Q9BV86,Q00535,Q7Z460,Q9BT25,Q9BUF5,O75116,Q14999,O60333,Q9UH99,P57076,Q96S59,Q96CW5,Q99661,Q9BW83,Q9Y2T2,Q14155,Q96P70,P43034,P36404,Q8TD16,Q14204,Q15398,Q9Y295,Q9HBM1,Q9H6U6,O95067,Q9UBF2,Q96Q89,Q16512,O96017,Q99996,Q9BTW9,Q92974,Q8TEW0,Q15257,Q7Z4H7,Q9BSJ2,Q00796,O43237,Q9UIS9,Q9HC35,P43487,O75935,O60610,O00203,P42858,Q13885,P63172,Q15691,Q8NI35,P52732,Q15813,P78559,Q14008,Q96N67,O14980,O15344,P33176,P16949,P29372,Q96EB6,P35579,Q15334,Q14203,Q9NZ32,Q13153,Q03001,O75351,O43264,P15311,P14635,P27695,P68371,P78318,P33981,Q15555,Q66K74,O14965,P04350,P07437,Q15058 81 +Negative regulation of actin filament bundle assembly 0.2062996717931449 0.0841688293551919 0.9329222007929656 1.0 1.0 9 Q13177,Q7Z460,P16949,P07737 4 +Appendage development 0.2079517064598763 0.0840929738475367 0.9329825109154536 1.0 1.0 18 Q96AC1,O75569 2 +Inner cell mass cell proliferation 0.2332864185965531 0.083683675523192 0.9333079366587572 1.0 1.0 7 P61201 1 +Cell projection organization 0.2584926276471613 0.0834642348984547 0.9334824145500156 1.0 1.0 261 O00560,Q8NCA5,Q00535,Q9UQB8,P60953,P50395,P46940,Q86X55,Q3SYG4,Q14999,Q9BPU6,P57076,Q96TA1,Q9BW83,Q9Y263,Q9P258,Q99707,Q05086,O60678,Q14155,Q9P265,O95487,P50570,Q9H4M9,P43034,Q93008,Q32P28,Q9BPX3,Q9Y3I1,Q9Y5K8,Q9H6U6,Q6IBS0,Q96Q89,Q16512,O00401,P51114,Q08209,Q8TEW0,Q8N0X7,Q9UL15,Q9HCE1,Q16513,Q9UIS9,A0AVT1,P42858,P46109,Q9UBB6,Q15691,Q8TC07,P47756,P41440,Q9NT62,P78559,Q06787,Q9NZQ3,Q96N67,P10155,P33176,P16949,P09429,P35241,P51116,P35579,Q9Y5Y2,Q13618,Q15334,Q14203,P00374,O60493,Q06124,Q9UPY3,Q92538,Q13153,P07900,Q01968,P07737,P15311,P27695,Q15555,Q96QK1,P00492,Q9Y3P9,P08238,Q99873,P78344,Q13555,Q66K74,Q13464,O15357,P10589,O14965,P83731,Q14141,Q86Y56,Q14012,Q9Y5K6,Q9NVG8,P35080,P42574,Q13614 100 +Enzyme linked receptor protein signaling pathway 0.2128567438575922 0.0833289775627439 0.9335899596510452 1.0 1.0 119 P53999,P62993,Q9UQB8,P33981,Q93034,Q16539,Q92600,Q16512,Q9UPN9,P22681,Q9Y3F4,P19174,P11802,O43318,P08238,P67870,P16949,P51452,Q96AC1,Q96TA1,P40763,O00443,Q96EB6,Q9C0C9,Q6Y7W6,Q8N0X7,Q13526,Q8IXJ6,P31751,P20248,Q14155,Q06124,P14735,P28482,P43490,Q96B36,P50570,Q13153,Q9Y5X3,Q93008,P46109,O14654,P42574,P27695 44 +Response to wounding 0.1807387311593849 0.0833017552937646 0.9336116046249004 1.0 1.0 80 Q00535,Q7Z460,Q16539,Q13310,Q16512,O00299,Q13572,Q8WTV0,Q96AY3,Q96AC1,Q08209,P21359,P35579,Q99439,O14965,Q99707,O00330,P00374,P20248,Q9Y490,Q9UNN8,P45985,Q13153,O00203,P42574 25 +Intraciliary transport involved in cilium assembly 0.3529411764705823 0.0832792847292277 0.933629471459916 1.0 1.0 3 Q15154,Q9UIS9 2 +Positive regulation of signaling 0.2466571339441445 0.0831472900221645 0.9337344239995842 1.0 1.0 262 P41440,P00813,Q9UMX5,Q00535,P60866,Q9UQB8,Q96K76,Q9NUD5,P41240,Q15555,Q14258,O60826,Q9Y3E0,O75116,Q16512,Q06787,Q13309,P22681,P62081,P08237,P36507,O00429,Q92499,O43318,P22059,P30046,Q15382,P67870,P09429,P19474,Q15648,P29372,Q96AC1,P40763,Q99873,P40818,Q96EB6,Q9BY44,Q9C0C9,P21359,Q14790,O95071,P61086,O00330,Q05086,P20248,P63241,P49327,Q06124,P28482,O75569,Q13535,Q92734,P43034,Q9UHD2,Q9H8V3,P18615,P42858,Q9Y5X3,O14744,Q13501,O75179,Q15042,P27695 64 +Regulation of phosphorus metabolic process 0.2275942652239116 0.0826417678661013 0.934136388892123 1.0 1.0 261 O00560,O00410,Q05639,Q00535,P17655,P60953,P52564,Q99570,P46940,Q9UNI6,O75116,Q13546,O75874,O60921,Q9UPR3,Q99627,P31751,P61086,Q08AM6,Q96B36,P36404,Q9Y3I1,O95067,Q9UER7,Q92796,Q16512,O96017,P22681,Q99996,P51114,P47897,P67870,Q92974,Q8TEW0,P21359,Q8IV63,Q5H9R7,Q15257,Q13432,Q9UIV1,O95373,P42858,P46109,Q96JP5,P60510,P41440,Q92990,Q69YH5,P42771,Q96KB5,Q06787,Q9Y376,Q8WTV0,Q96N67,O43318,P51452,P31689,P40763,P51116,P49407,Q96EB6,Q8IXJ6,Q15334,P20248,P49327,Q06124,Q04637,Q92616,Q13153,P07900,Q9H8V3,O75909,A4D1P6,Q13501,P14635,P18669,P78318,P31946,P33981,P53350,P41240,Q92600,Q8WUA2,Q6PJG6,P36507,P22059,P08238,O75832,Q96AC1,Q9UII4,Q13526,Q13464,Q13043,P30307,Q8TBX8,P28482,Q14012,Q99741,P35080,Q9NYV4,Q9UHD2,Q15058,Q14738,P23381,P42574,P13010,Q13614 107 +Regulation of multicellular organism growth 0.2031173389609013 0.0825471745043232 0.934211606475548 1.0 1.0 16 Q14353,Q9HCL2,P11802,P40763 4 +Central nervous system neuron development 0.1946193779205521 0.0821712561920877 0.9345105303637342 1.0 1.0 12 P07900,P00492,Q00535,P43034 4 +Response to abiotic stimulus 0.2694216983499702 0.0818935050028863 0.9347313993489156 1.0 1.0 230 P49770,P11310,P00813,Q96K76,P17655,P18074,Q9UER7,O75116,Q16512,Q06787,P22681,P27544,Q99996,Q9Y487,Q99504,O60921,Q96RU2,P31689,P28340,P21359,Q96EB6,Q14790,P31751,Q13144,P55786,Q13432,P20248,Q00796,P49327,O95352,Q13535,Q6P6C2,Q9GZT9,P42858,Q9Y620,Q9NPQ8 36 +Mast cell cytokine production 0.5349253731343364 0.0817877747200593 0.9348154778628056 1.0 1.0 2 P09601 1 +Dna biosynthetic process 0.1764917234837675 0.0817428355818487 0.9348512144478368 1.0 1.0 76 P41440,P35251,Q9BUR4,Q14694,Q96HR8,P49005,P27544,P08238,P27694,Q96BK5,Q96TA1,Q9UPR3,P18858,Q96EB6,P28340,P49368,P50991,P40227,Q8IZH2,P04183,P28482,P17987,Q13535,Q99832,P07900,Q9Y4R8,Q07864,Q15554,P13010,Q9BRT9,P48643 31 +Cellular response to dna damage stimulus 0.2183322468288154 0.0816863154474934 0.9348961606805252 1.0 1.0 257 P41440,Q96K76,P54277,P25205,Q7Z6Z7,Q9Y3Z3,Q9BUR4,Q9ULC4,P18074,Q92547,Q16512,Q9UQ84,P49005,O00487,P23921,P22681,Q06787,Q9H4L7,P35244,P38935,P13693,Q99504,Q14997,P46379,P46063,O60921,P09429,Q7Z4V5,Q96FW1,Q96RU2,P29372,P18858,P28340,Q96EB6,Q15645,Q92759,O95071,P20585,P52701,Q06124,P28482,P57081,Q13535,Q7Z7L1,Q86WJ1,Q96T76,Q9H993,P36915,Q9NUW8,P42574,Q07864,Q9Y620,Q96FZ2,P27695 54 +Wound healing 0.1637819088659039 0.081365995355575 0.9351508911921524 1.0 1.0 62 Q7Z460,Q16539,Q13310,Q16512,O00299,Q8WTV0,Q13572,Q96AY3,Q96AC1,Q08209,P21359,P35579,Q99439,P20248,Q9Y490,Q9UNN8,Q13153,O00203,P42574 19 +Notch signaling pathway 0.201717304747527 0.0812167802700458 0.9352695548745664 1.0 1.0 16 Q00534,Q96TA1,P40763,P49407 4 +Positive regulation of translation 0.1627011727426417 0.0809785220533717 0.9354590333174246 1.0 1.0 61 Q7Z478,Q6PKG0,P14618,P62701,Q567V2,Q13144,Q96P11,P63241,O75534,P13639,P67809,Q06787 12 +Negative regulation of sodium ion transmembrane transport 0.5337313432835902 0.0809042727597986 0.9355180819364411 1.0 1.0 2 O95747 1 +Extracellular transport 0.5337313432835902 0.0809042727597986 0.9355180819364411 1.0 1.0 2 Q99816 1 +Positive regulation of cellular component organization 0.1983068566527794 0.0805049903169913 0.9358356274205644 1.0 1.0 252 Q8NCA5,Q00535,Q9UQB8,Q7Z460,P17655,O75116,Q14999,P27544,P49427,Q86VP6,P31751,Q14155,P17987,Q13535,P50570,Q9H4M9,P43034,P36404,Q32P28,Q14204,Q9Y613,Q15398,Q15042,Q9BPX3,Q9Y3I1,Q9Y295,Q9H6U6,Q6IBS0,Q16512,P22681,O00401,Q99996,P35611,P26358,P39748,Q08209,Q9UJX4,Q9NTJ3,P42858,Q15021,Q15003,Q15691,P62195,P48643,P41440,Q16539,O14737,Q06787,Q9NZQ3,Q14008,O00429,P51452,P60981,P49407,P49368,Q8IXJ6,Q13618,Q15334,Q14203,Q13283,O60493,Q04637,Q13153,P07900,O95347,O75351,P07737,A5YKK6,P27695,Q15555,Q96HR8,P22059,Q96AC1,O14965,P63241,P28482,P35080 77 +Cellular component morphogenesis 0.2274968235789162 0.0804125777054424 0.9359091237376288 1.0 1.0 142 P41440,Q00535,Q9UQB8,Q7Z460,Q6IBS0,P18074,Q96Q89,P78559,Q16512,Q14999,Q9BPU6,Q96N67,P00492,O00429,P16949,Q96TA1,Q08209,Q9Y263,Q8N0X7,Q66K74,O14965,Q05086,O60678,Q14155,Q9P265,Q06124,P50570,P43034,Q93008,Q13614 30 +Telomere maintenance via telomere lengthening 0.1986537283876894 0.0803544256664488 0.9359553726911104 1.0 1.0 44 P41440,P35251,Q9BUR4,Q96HR8,P08238,P27694,Q96BK5,Q9UPR3,P49368,P50991,P40227,Q8IZH2,P28482,P17987,Q13535,Q99832,P07900,Q9Y4R8,P13010,P48643 20 +Positive regulation of cell population proliferation 0.2218347268595067 0.0802467672916189 0.9360409951459469 1.0 1.0 134 Q8NCA5,P00813,Q9ULC4,Q96Q89,Q16512,O76071,Q9NR09,P19174,P11802,P26358,P09429,Q96AC1,Q15648,Q99873,P40763,P78362,P21359,Q96EB6,Q9HCL2,P31751,P20248,P62753,P28482,P43490,Q7Z5K2,P15531,Q15058,Q00534,O60884,O95630,P14635,P53602 32 +Positive regulation of neuron differentiation 0.187612208258519 0.0802294797678302 0.9360547442634732 1.0 1.0 10 Q9P2X3,O60271,P61586,Q9H8V3,Q96ST3,Q99829,Q04637,Q92974,P46821 9 +Regulation of neutrophil chemotaxis 0.2301943198804277 0.0802039053289322 0.9360750841672644 1.0 1.0 7 Q07021,O00429,Q8NHP6,O94813,P63000,Q00013 6 +Regulation of hydrolase activity 0.2482655743644445 0.0799934482906409 0.9362424667798468 1.0 1.0 177 O00170,Q96K76,P61221,Q9P0J0,Q15555,O14737,O75116,Q15392,Q96N67,O60343,Q9NR09,Q14997,Q04323,P61289,P09429,P67870,P16949,P40763,Q96EB6,P21359,O43847,Q9Y263,Q14790,Q15257,Q86X10,P31751,P20248,Q14155,P49327,P30086,Q9GZT9,Q9H8V3,P42858,Q8TC07,Q15042 35 +Production of molecular mediator of immune response 0.2068520557160469 0.0798985942891842 0.9363179078517208 1.0 1.0 39 Q96EB6,Q9Y3Z3,O43318,P20585,P52701,Q96FZ2,Q16512,Q9UQ84 8 +Negative regulation of response to stimulus 0.1982447127861082 0.0798148550591485 0.9363845093893411 1.0 1.0 249 Q9UMX5,Q7Z460,Q9Y3Z3,Q96IZ0,P13693,P49427,Q96S59,Q96TA1,P28070,P80303,O00330,Q96P70,Q96B36,P50570,Q96BN8,P43034,P67809,Q01804,P00813,Q9P0J0,Q99956,P25786,O96017,P22681,Q99504,P48506,P47897,P30046,P39019,Q92974,P21359,Q8IV63,Q8N0X7,Q14790,Q9UL15,Q9UIV1,P30086,P42858,Q00534,Q04727,P48507,Q96K76,Q96C57,Q16539,Q14694,O60826,Q96KB5,Q9UPN9,Q14166,Q9HCK8,Q9NR09,Q04323,P61289,P16949,P51452,P19474,P31689,P19784,Q96EB6,P49407,Q8IXJ6,Q13618,Q6GQQ9,Q13283,Q99471,Q9NRR5,Q9Y5X3,O95630,A5YKK6,P15311,P78318,P31946,P41240,Q92600,Q14152,Q9Y3F4,Q96QK1,P19174,Q96FW1,Q8IWV7,O95071,Q8TAT6,Q9Y5K6,Q13614 84 +Autophagosome maturation 0.1981497200373357 0.0796705263873661 0.9364993014518774 1.0 1.0 15 Q99570,Q9Y4P8,Q9H269 3 +Protein nitrosylation 0.5319402985074707 0.0795998063329971 0.9365555492532948 1.0 1.0 2 P11766 1 +Pyruvate metabolic process 0.2015705288545579 0.0789843360667521 0.9370450821437024 1.0 1.0 42 P51570,P09972,P08237,P14618,P36404,P17858,O00330,P85037,P18669,P40763 10 +Substrate dependent cell migration 0.2151774778692747 0.0789360059637886 0.9370835239629236 1.0 1.0 8 O00560,Q9Y5K6,Q13043 3 +Myeloid leukocyte migration 0.2109512090045014 0.0787941439509508 0.9371963620170078 1.0 1.0 26 P09429,P30046,Q92538,O00429 4 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.347300339850162 0.0787589550200679 0.9372243517382568 1.0 1.0 3 Q7Z6Z7 1 +Response to nitrogen compound 0.2017844414240295 0.0782107225133603 0.937660432813838 1.0 1.0 242 P49770,P55210,P41440,P63151,Q00535,Q9UQB8,P17655,Q9NUD5,P41240,Q9UER7,Q14258,O75116,Q06787,Q99996,O60343,P14618,P09960,P00492,Q04323,P46379,P11802,P26358,Q8IWV7,Q08209,P40763,P49721,Q96EB6,Q6PKG0,O15357,Q99707,P31751,Q13144,P55212,P00374,Q05086,P20248,P07741,Q06124,P28482,P43490,Q8TAT6,Q9GZT9,Q5VYK3,Q9Y5X3,O14744,P42574,P28161,P27695 48 +Cellular response to endogenous stimulus 0.2100453977107737 0.0780035169509967 0.9378252553966824 1.0 1.0 241 O00560,O00410,P55210,Q00535,Q9UQB8,P17655,P46940,O75116,Q86X55,Q7L576,Q53EL6,P14618,Q9HCM4,Q9NZN8,P11802,Q15648,Q9C0C9,P31751,P55212,Q05086,P14735,P50570,Q9H4M9,Q93008,Q9P2J5,Q9H6U6,Q9UER7,Q16512,P22681,Q99996,P48506,P26358,P61960,P67870,Q92974,P40818,Q8N0X7,P07741,O43237,P43490,O60610,P46109,P48507,O14737,Q9UPN9,P68036,P07814,O43318,P51452,P35241,P40763,Q96EB6,Q8IXJ6,P20248,Q06124,Q13153,P06730,Q9Y5X3,O14654,A5YKK6,P15311,P27695,P62993,P41240,Q969T9,Q92600,Q13309,Q9Y3F4,Q96QK1,O60343,P19174,P08238,Q8IWV7,Q96AC1,O00443,Q13526,Q6PKG0,Q13464,O95071,Q8TBX8,Q8IZH2,P28482,Q99741,Q04206,Q9NUQ7,P42574,O14744,P17612,P28161 89 +Reproduction 0.2185220314813386 0.0778275278226552 0.9379652488212458 1.0 1.0 240 P17655,O95394,Q9UQ84,Q14999,Q15392,O75874,O60566,Q9UH99,Q96CW5,O60921,Q14157,Q15648,Q96SB4,Q9BW83,Q08J23,Q05086,O75534,P17987,P50570,P43034,Q6P6C2,Q93008,P49770,Q9Y696,P00813,Q8NHU6,O95067,Q5TAX3,P22681,P04075,Q14997,Q14790,Q13144,Q9BSJ2,Q00796,Q9NTJ3,O00203,P46109,Q9Y620,Q15021,Q15003,P48643,P41440,P11172,P46926,Q16539,Q15056,Q9H1B7,Q14353,Q9NR09,O43684,P25440,P40763,P19784,Q96EB6,P47914,P35579,P49368,Q8IXJ6,P20248,Q06124,Q9UNF1,Q7Z7E8,O95347,O43264,P62993,P33981,P53350,P42695,Q9H6S0,P46379,Q96PU8,Q9ULT8,Q15645,O14965,P30307,P52701,P62753,P28482,Q6IBW4,P42574 81 +Positive regulation of catabolic process 0.2335049064852546 0.0777819701624548 0.9380014887182312 1.0 1.0 155 P62191,Q9Y3I1,P15311,P43686,Q9P0J0,P53350,Q7Z6Z7,Q9C0B1,Q92900,Q5TAX3,O60826,Q6L8Q7,O75116,Q06787,P27544,Q96QK1,P46379,P48506,O43318,P45974,O75832,P09429,P19474,Q969T7,Q86TB9,P35241,O00178,O00443,Q9Y5A7,Q96EB6,O43847,Q9ULT8,Q6Y7W6,Q6PKG0,Q13464,Q8IXJ6,O14965,P31751,Q5PRF9,Q9UIV1,O75534,O95376,P14735,Q9HCE1,O95352,Q9Y2L1,Q96C86,O75150,P07900,Q9UHD2,P42858,P67809,A5YKK6,P62195,Q86W50,Q15042 56 +Membrane depolarization during action potential 0.5292537313432909 0.0776894186838335 0.9380751113329144 1.0 1.0 2 Q04917 1 +Hematopoietic progenitor cell differentiation 0.210587786154314 0.0773691198976317 0.9383299058783804 1.0 1.0 29 Q00534,Q9NPH0 2 +Regulation of cytokinesis 0.2099903054251166 0.0773344009222457 0.9383575248628252 1.0 1.0 27 Q99741,Q13526,Q9NR09,P53350,O14965,Q13618,Q9H8V3,Q15058,Q99570,Q96Q89,Q16513 11 +Organelle assembly 0.1372053854652155 0.0772742181585214 0.938405400495546 1.0 1.0 238 P62750,Q9Y295,P15311,O95239,P52732,Q7Z460,Q9Y5K8,P53350,Q9NT62,O95067,Q15555,Q9BT25,Q7Z2Z2,Q9Y4P1,P50748,O96017,Q96F86,Q3SYG4,Q7Z478,P26196,P27635,P57076,Q9Y3P9,P10155,Q96CW5,Q14157,P39019,P35241,Q86TB9,Q9NUL7,Q9BY44,Q13045,P83731,Q9Y4P8,Q7Z4H7,O14965,Q567V2,Q14141,Q9BSJ2,Q14203,Q9UIV1,Q13283,P07437,O75534,A1X283,Q8TBX8,P50851,Q86Y56,Q9UIS9,O95352,P05198,Q15691,Q92538,P50570,Q9H4M9,P43034,Q9Y520,Q9NVG8,Q9H9H4,P39023,P42858,O75351,P62266,P13010,Q01968,Q15042,Q14204,P62841,Q15398,Q8TC07,Q9BPX3,A5YKK6,P27695 73 +Cellular response to lipid 0.1989441093674617 0.0772467148501451 0.938427279563083 1.0 1.0 106 Q96EB6,Q8WTV0,Q9Y263,Q9P0J0,P17655,P68036,O95071,Q05086,Q9UER7,P20248,P61960,P09429,O75116,P28482,Q16512,Q13309,P40818 17 +Positive regulation of leukocyte cell cell adhesion 0.2092220826415678 0.0770579021936534 0.938577482560378 1.0 1.0 26 P00491,P00813,Q04206,Q9HCL2,P41240,O00203,P09429,Q06124,O14617 9 +Regulation of cell population proliferation 0.1967957740263203 0.0770558024892751 0.938579152915632 1.0 1.0 237 Q8NCA5,P00813,Q92990,P41240,Q96IZ0,P42771,Q9ULC4,Q96Q89,Q92796,O14737,Q16512,Q96DY7,Q15392,O76071,P35244,Q9NR09,P19174,P11802,P26358,P09429,P67870,Q96AC1,Q15648,Q99873,Q96TA1,P40763,Q99627,P78362,P21359,Q96EB6,Q9HCL2,O15357,P31751,P20248,P62753,P28482,P43490,O75569,Q7Z5K2,P15531,Q15058,Q00534,O60884,P42574,O95630,P14635,P53602 47 +Phagocytosis 0.2031681065041031 0.0768175579544585 0.9387686827827136 1.0 1.0 40 Q8WTV0,P41240,Q9NT62,Q14185,O60493,P09429,Q16512 7 +Cellular response to hormone stimulus 0.2163055089039813 0.0767389275159059 0.9388312361507664 1.0 1.0 130 Q9UQB8,P41240,Q9UER7,O75116,Q16512,Q13309,O60343,P14618,P68036,P11802,P61960,P67870,P40763,P40818,Q96EB6,O95071,P31751,Q05086,P20248,P07741,Q06124,P43490,Q9NUQ7,Q9Y5X3,P27695 25 +Regulation of cell differentiation 0.1927178426818256 0.0765917290514949 0.938948338886702 1.0 1.0 235 Q9Y3I1,P00813,Q00535,Q8N4Q0,Q9UQB8,Q7Z460,Q9C0B1,Q6IBS0,P22392,O75116,O96017,Q14999,O00299,P11413,Q96N67,P26196,P35611,P26358,Q15382,P39019,P09429,Q96AC1,Q15648,Q86TU7,Q96TA1,Q08209,Q92974,P40763,Q99873,Q96EB6,P21359,Q8N0X7,Q9P258,Q14790,O14965,Q08J23,Q14185,P20248,Q14155,Q9P265,Q06124,P28482,Q9UIS9,P00491,O95628,P50570,P43034,Q9H8V3,O15347,O00203,Q15058,P46109,Q92688,Q00534,O14744,O75179,P67809,P27695 58 +Negative regulation of cell death 0.156943308327566 0.076583213792184 0.9389551131836784 1.0 1.0 235 Q9Y3I1,P00813,Q9UMX5,Q00535,Q9NX46,Q96K76,Q9P0J0,Q92614,Q9BXJ9,P22392,P22681,Q15392,P13693,Q9NR09,P27635,Q99504,P46379,P48506,P47897,P26358,P61289,P08243,P61960,Q96AC1,Q15648,P31689,Q96TA1,P19784,Q96EB6,Q01105,Q9C0C9,Q9HCL2,Q14790,O14965,P31751,O00330,P20248,P49327,P62753,P51858,Q5VZE5,P45985,Q92905,Q96C86,O95630,Q15058,P42858,P42574,Q969U7 49 +Negative regulation of cell division 0.5274626865671725 0.0764463598363093 0.9390639876716212 1.0 1.0 2 Q9UN37 1 +Telomeric d loop disassembly 0.5274626865671723 0.076446359836309 0.9390639876716214 1.0 1.0 2 Q15554 1 +Telomeric loop disassembly 0.5274626865671723 0.076446359836309 0.9390639876716214 1.0 1.0 2 Q15554 1 +Posttranscriptional regulation of gene expression 0.211670742332199 0.0764209499048168 0.9390842027280956 1.0 1.0 234 O75116,P14618,P26196,P27635,P46199,Q92499,Q9BY44,Q8IWR0,Q567V2,P31751,Q8TEQ6,Q08J23,O75534,P13639,Q9HAV4,Q14240,O75569,Q9H814,Q6P6C2,Q96P11,P67809,Q86W50,P49770,Q9BX40,Q9Y2V2,Q8NHU6,Q9C0B1,Q5TAX3,Q13310,P41567,P62701,P62495,P51114,Q969T7,Q86TB9,Q08209,Q6Y7W6,Q13144,Q9UIV1,Q9HCE1,Q9Y2L1,P05198,Q16539,Q15056,Q06787,Q7Z478,P07814,P40763,P51116,Q5PRF9,P00374,Q04637,Q92616,Q9UPY3,Q7L8L6,Q96C86,Q9BQC3,P06730,Q9Y450,O60573,A5YKK6,P21399,P27695,P61221,Q92900,Q92600,Q96HR8,Q6L8Q7,O60841,P36507,P42694,O43432,Q96PU8,O15371,P78344,Q6PKG0,Q13464,P55010,P63241 79 +Positive regulation of dna recombination 0.2093316607869991 0.0763115079239936 0.9391712705432664 1.0 1.0 28 Q96FZ2,Q9BUR4,Q7Z4V5 3 +Regulation of cellular component biogenesis 0.2097757832596034 0.0761825613470266 0.939273856395223 1.0 1.0 233 O00560,Q8NCA5,Q9UQB8,P62333,Q7Z460,P60953,P50395,O75116,P47755,Q7L576,Q9HCM4,Q9Y6B6,Q9NZN8,P49427,Q86VP6,Q9P258,Q14155,Q13535,P50570,P36404,Q14204,Q9Y613,Q15042,Q9BPX3,Q9Y295,Q9H6U6,Q6IBS0,Q16512,O15020,O00401,Q99996,P35611,P51114,P26358,Q9BTW9,Q96BK5,Q9UL15,Q9UEY8,P42858,Q15691,Q8TC07,P62195,P47756,P41440,Q9NT62,Q06787,Q14008,P09429,P16949,P51452,P35241,P51116,Q8IXJ6,Q14203,Q13283,P20248,Q06124,Q04637,Q9NR31,Q13153,P07900,Q9H8V3,O75351,P07737,A5YKK6,P15311,P54920,P27695,P62993,P53350,Q15555,Q96DE0,Q96QK1,Q9Y3P9,Q96AC1,Q13464,Q13045,P04350,Q8TBX8,P35080,Q9NVG8,Q15058,Q9H2G2,P23381,P17612,P13010 86 +Immune response 0.2410524584527166 0.0759161229627855 0.9394858296068568 1.0 1.0 227 Q9Y3Z3,Q96IZ0,Q9NW08,Q9UQ84,Q92499,Q15648,Q96SB4,P28070,P78362,P61086,P55212,O75569,P45985,Q96BN8,Q01804,P49770,P00813,Q9NUD5,Q14232,P25786,Q16512,P22681,O00743,O15111,Q9Y487,P39019,Q92974,Q14790,Q13144,Q9UIV1,P00491,O95801,O95373,Q8IWZ3,P36915,O15347,O00203,P46109,Q96FZ2,P41440,Q16539,Q14258,Q14166,Q9BUI4,P07814,O43318,P33176,P09429,P51452,P19474,P40763,Q96EB6,Q8IXJ6,Q6GQQ9,Q13283,P49327,Q06124,Q9NR50,Q92538,Q13153,P07900,O75179,P15311,P41240,Q13309,Q00653,O14802,P00492,P19174,P46379,Q96FW1,Q9Y5A7,Q9UII4,P07437,P52701,P62753,P28482,Q8TAT6,Q9UHD2 79 +Positive regulation of catalytic activity 0.2513299747288293 0.0758937037949039 0.9395036660578382 1.0 1.0 212 Q05639,P31946,Q9P2J5,Q00535,Q9P0J0,P41240,Q9BUR4,Q15555,Q99570,Q9UER7,Q9UNI6,O14737,Q92796,O75116,Q96HR8,Q16512,O00487,Q8WTV0,Q96N67,O60343,P68036,Q14997,P36507,O43318,P61289,P09429,Q96AC1,P40763,Q99627,Q96EB6,P21359,Q9Y263,Q9P258,Q15257,Q14790,Q86X10,P31751,Q13432,P00374,Q08AM6,Q14155,P20248,P20585,P49327,P52701,P28482,Q92616,P17987,Q9H8V3,Q15058,Q92688,P14635,Q96JP5,Q8TC07,Q9BRT9,Q15042,Q16763 57 +Mannosylation 0.2119816480731261 0.0758365320599127 0.9395491514181096 1.0 1.0 8 Q9BV10 1 +Viral gene expression 0.2023530079827328 0.0757639041801495 0.9396069338439068 1.0 1.0 40 O75821,P41214,P05455,Q9ULC4,O14646,O75534,P19474,Q99873,Q14152 9 +Positive regulation of mrna metabolic process 0.1637278978167992 0.0754321984059495 0.9398708415552588 1.0 1.0 65 Q5TAX3,O75116,P67809,Q86TB9,Q86W50 5 +Positive regulation of protein k63 linked ubiquitination 0.5256716417910532 0.0752274501617172 0.9400337441594504 1.0 1.0 2 O00571 1 +Dna repair 0.2455420138850636 0.0750948422580605 0.9401392515210742 1.0 1.0 187 P41440,Q96K76,P54277,P25205,Q7Z6Z7,Q9Y3Z3,Q9BUR4,P18074,Q92547,P49005,Q9UQ84,O00487,P23921,Q9H4L7,P35244,P38935,Q99504,Q14997,P46063,O60921,P09429,Q7Z4V5,Q96FW1,Q96RU2,P29372,P18858,P28340,Q96EB6,Q15645,Q92759,O95071,P20585,P52701,Q13535,Q86WJ1,Q96T76,Q9NUW8,Q07864,Q9Y620,Q96FZ2,P27695 41 +Antigen processing and presentation of exogenous peptide antigen 0.2707169581877049 0.075023739835502 0.9401958234613446 1.0 1.0 4 Q03518,P50570 2 +Cellular component assembly involved in morphogenesis 0.1996278102664103 0.0750219197542779 0.9401972715949573 1.0 1.0 19 P43034,Q7Z460,P18074,Q9UPY3,Q13614 5 +Mesenchymal cell differentiation 0.2065711281603769 0.074679531965733 0.9404696933148136 1.0 1.0 35 O75116 1 +Regulation of transferase activity 0.2440264183565381 0.0746369193285065 0.9405035986567 1.0 1.0 185 O00410,Q05639,Q9Y3I1,P60866,Q00535,P49643,P53350,P60953,Q9BUR4,P52564,P41240,O95067,Q99570,P42771,Q9UER7,Q9UNI6,Q96HR8,Q92796,Q16512,P27544,P22681,Q9Y376,P62081,O60566,P68036,O43684,O00429,P36507,P47897,O43318,P08238,O75832,P51452,Q96BK5,Q96AC1,P31689,Q99627,Q96EB6,P21359,Q9UII4,Q13526,Q13043,Q9UL15,Q15334,Q13432,P20248,Q08AM6,P30307,Q8TBX8,P28482,Q14240,P17987,Q92616,Q14012,P15880,Q96B36,Q99741,O95373,Q13153,P07900,Q9NYV4,Q9H8V3,Q15058,P42858,O75909,A4D1P6,P23381,Q96JP5,P42574,P62841,P14635,Q9BRT9,P13010,Q16763 74 +Cell division 0.2363035109327416 0.0742935381833216 0.940776818606576 1.0 1.0 220 Q00535,Q7Z460,Q99570,Q9BT25,Q6P1K2,O75116,P50748,Q14999,O60566,P11802,P18858,Q99661,Q9H900,Q9P258,Q08J23,P43034,Q93008,Q14204,P67809,Q9BPX3,Q9P0V9,Q9HBM1,Q9H6H4,O95067,Q96Q89,O96017,O00401,Q92974,Q8TEW0,P40818,Q2NKX8,Q8N0X7,Q7Z4H7,Q9UJX4,Q13432,Q9NTJ3,Q16513,Q9HC35,O75935,Q00534,Q15021,Q15003,P63172,Q15691,P52732,Q16763,Q6NUK4,Q69YH5,Q9BTE3,P18074,Q96CT7,Q14008,Q96N67,Q9NR09,O43684,P16949,P35579,Q8IXJ6,Q13618,Q14203,P20248,Q7Z5K2,Q99986,Q9H8V3,O95347,O75909,O75351,O43264,O95630,P14635,P53350,P42695,Q8TD19,Q15555,Q9Y6G9,Q9NXR7,Q9NRZ9,O43683,Q13526,Q13464,O14965,Q14141,P07437,Q8IX90,P30307,Q29RF7,Q99741,Q9UJX5,Q9Y5K6,Q15058,Q00610 91 +Camera type eye development 0.2071611167486792 0.0742269439293067 0.9408298068280888 1.0 1.0 33 Q15293,P21359,Q15555,Q8NHU6,Q15042,Q15648,O75569 7 +Negative regulation of molecular function 0.2071815296291549 0.0741297579022703 0.9409071370137454 1.0 1.0 224 Q9Y3I1,P60866,P31946,O00170,Q96K76,P61221,Q9H6U6,P41240,P42771,O60826,O75116,Q7L2J0,Q16512,P78417,Q06787,O60256,O14981,P27544,P22681,O15111,P62081,Q15392,Q99996,O60566,O00221,Q9NR09,Q9Y314,Q04323,P47897,P16949,Q86VP6,P19474,P31689,Q08209,Q96EB6,Q01105,Q9C0C9,P21359,Q9P258,Q15257,O14965,Q9Y570,P61201,Q14240,P30086,Q7Z5K2,Q96B36,Q96BN8,P36404,Q9GZT9,P35269,P42574,P28161,Q9BTT0 54 +Membrane protein ectodomain proteolysis 0.2100794700531886 0.0740845266337988 0.9409431273815264 1.0 1.0 8 O43847,P35579 2 +Neuron differentiation 0.2111630871593751 0.0739434350962469 0.941055394216636 1.0 1.0 223 Q9Y3I1,P41440,Q00535,Q9UQB8,Q15555,Q6IBS0,P18074,Q96Q89,P78559,Q16512,Q06787,Q9NZQ3,Q14999,O60701,O00401,Q9Y3F4,Q9BPU6,Q96N67,P63104,P26196,P00492,P08238,P33176,P16949,Q9BTW9,P09429,Q15648,Q99873,Q96TA1,Q92974,Q08209,Q8TEW0,P40763,Q9BW83,P78344,Q13555,Q9Y263,Q8N0X7,Q6Y7W6,Q13464,Q66K74,P10589,Q99707,O14965,Q13526,Q9UL15,Q15334,P00374,Q05086,O60678,O60493,Q9P265,Q06124,Q9HCE1,Q04637,Q9UPY3,P61201,O95487,P50570,Q9H4M9,P43034,Q13153,P07900,P06730,Q9H8V3,A0AVT1,Q93008,P46109,Q32P28,Q9UBB6,P42574,P54920,Q13614 73 +Convergent extension 0.522985074626874 0.0734438381476965 0.9414529339675604 1.0 1.0 2 Q13308 1 +Genomic imprinting 0.5229850746268742 0.0734438381476965 0.9414529339675604 1.0 1.0 2 Q6PD62 1 +Regulation of genetic imprinting 0.5229850746268742 0.0734438381476965 0.9414529339675604 1.0 1.0 2 Q6PD62 1 +Collagen metabolic process 0.2093150283391044 0.0733995677229864 0.9414881615763002 1.0 1.0 8 Q32P28 1 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.1793065651038784 0.0732198855669537 0.9416311424653352 1.0 1.0 50 P53999,O00560,P33981,Q16539,Q9UPN9,Q53EL6,Q9Y3F4,O43318,Q13418,P08238,P67870,Q96AC1,P40763,Q96EB6,Q9C0C9,Q13526,Q8N0X7,P20248,Q8NC56,P50570,Q93008 21 +Regulation of lymphocyte migration 0.2233183856502327 0.0731191923975313 0.9417112692126756 1.0 1.0 7 O95747,O00401,Q5JRA6,P61586,P46109,P26038 6 +Heart formation 0.3395043296506403 0.0730524585130424 0.9417643731309222 1.0 1.0 3 Q8NC56,Q06330 2 +Proximal distal pattern formation 0.3395043296506392 0.0730524585130416 0.9417643731309228 1.0 1.0 3 O95747,P31260 2 +Centriole centriole cohesion 0.3395043296506354 0.0730524585130391 0.9417643731309248 1.0 1.0 3 Q14203,Q9Y496 2 +Leukocyte cell cell adhesion 0.1893516898835754 0.0729895066623591 0.9418144677087156 1.0 1.0 46 P00491,P00813,Q04206,Q13464,Q9HCL2,Q92990,P41240,O00203,Q96IZ0,P09429,P51452,Q92598,P42574,O14617,P15311,Q06124 16 +Negative regulation of peptidase activity 0.201281765489052 0.0728712948655282 0.941908536574529 1.0 1.0 39 P30086,Q15392,Q9NR09,Q96K76 4 +Embryo development 0.2330317174601782 0.0728105063257496 0.9419569103109022 1.0 1.0 213 Q03164,P00813,O43772,Q7Z460,P17655,Q92990,Q8NHU6,O95067,P18074,Q96Q89,Q92796,O75116,Q9H0G5,O60701,Q13572,P62081,Q9NR09,P27635,P46379,O60921,P26358,Q8IWS0,Q96AY3,Q15648,Q99873,Q96TA1,P21359,Q9UPT9,Q9ULT8,Q14790,Q08J23,O00330,P20248,P61201,P62753,P28482,O75569,O95487,Q15293,P26572,Q6W2J9,Q07864,Q9NPQ8,P42574,P67809,P14635,P20290 47 +Tube morphogenesis 0.2015194520893044 0.0724516425508026 0.9422424879306122 1.0 1.0 114 Q9Y696,Q92990,Q9BXJ9,Q96Q89,O75116,Q16512,Q14999,P62081,P14618,P19174,Q96PU8,P67870,Q96AY3,Q15648,Q96TA1,P40763,P78362,P21359,Q96EB6,Q9ULT8,Q14790,P20248,O95487,Q96BN8,Q9GZT9,P42574 26 +Maintenance of protein location 0.2053207994834479 0.0720123099351891 0.9425921113752644 1.0 1.0 31 O00221,P31946,Q00535,Q9UH99,P36404,O60826,P24390 7 +Skeletal muscle acetylcholine gated channel clustering 0.266427718040616 0.0713245597695483 0.9431394491336832 1.0 1.0 4 P46109,Q96EY1,O15258 3 +Cellular response to oxygen containing compound 0.1869458109578832 0.071307645407038 0.9431529105664898 1.0 1.0 212 Q9P2J5,Q00535,Q9NX46,Q9UQB8,Q9P0J0,P17655,P41240,Q96IZ0,Q6IBS0,O75116,O96017,P27544,O15111,Q8WTV0,Q99996,O60343,P14618,P11802,P48506,P22059,P26358,P09429,Q8IWV7,Q15648,Q08209,P40763,P40818,Q96EB6,Q9Y263,Q6PKG0,Q99707,P31751,O00330,P00374,P20248,P07741,Q06124,P14735,P28482,P43490,P50570,Q96C86,Q9H8V3,Q9Y5X3,O14744,P27695 46 +Mesenchyme development 0.2008908800038171 0.0711886668522774 0.9432476010743772 1.0 1.0 38 O75116 1 +Eyelid development in camera type eye 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 1.0 2 Q13547 1 +Lung secretory cell differentiation 0.5191044776119489 0.0709608066914641 0.9434289485502558 1.0 1.0 2 Q13155 1 +G1 to g0 transition involved in cell differentiation 0.5191044776119489 0.0709608066914641 0.9434289485502558 1.0 1.0 2 Q96F45 1 +Regulation of cardioblast differentiation 0.5191044776119487 0.0709608066914638 0.943428948550256 1.0 1.0 2 Q9H2U1 1 +Positive regulation of cardioblast differentiation 0.5191044776119487 0.0709608066914638 0.943428948550256 1.0 1.0 2 Q9H2U1 1 +Lung saccule development 0.5191044776119487 0.0709608066914638 0.943428948550256 1.0 1.0 2 Q15185 1 +Regulation of cardiocyte differentiation 0.5191044776119487 0.0709608066914638 0.943428948550256 1.0 1.0 2 Q9H2U1 1 +Positive regulation of cardiocyte differentiation 0.5191044776119487 0.0709608066914638 0.943428948550256 1.0 1.0 2 Q9H2U1 1 +Nucleobase containing small molecule metabolic process 0.2326047124302427 0.0706767425711867 0.9436550312776916 1.0 1.0 198 Q08623,P34949,P00813,P11172,Q9Y3Z3,Q86TX2,P85037,P27708,P22392,O95394,P31350,P35754,P23921,O60256,O60701,O60725,Q06203,Q9BPU6,P30520,P09972,P04075,P14618,P49915,Q9NR45,P08237,P00492,P33316,Q06210,Q13126,P17858,P53396,Q96IU4,Q969T7,P31939,P40763,Q9P2T1,O00154,Q9HCL2,Q15126,Q9UKG9,O00330,P20839,Q01433,P07741,P04183,Q13057,P28482,P43490,P26572,P51570,Q9BY32,Q9BZX2,P36404,P15531,Q9UKK9,P53602,P17812,Q9NVE7,P30566,P18669,O15067 61 +Response to sorbitol 0.335921170498654 0.0706322665846348 0.943690429515279 1.0 1.0 3 P46734,P52564 2 +Regulation of immune system process 0.1720436284127955 0.0701402831608408 0.944082004311644 1.0 1.0 207 P49770,Q9Y3I1,P00813,P41440,Q92990,Q9NUD5,P41240,Q9Y3Z3,Q96IZ0,Q16539,Q14232,Q14258,Q92614,P25786,Q9NW08,Q16512,Q9H3U1,Q14166,O00401,Q9BUI4,P19174,O00429,P46379,Q92499,O43318,P30046,P09429,P39019,P19474,Q15648,Q99873,P40763,P28070,Q96EB6,P21359,Q9HCL2,Q14790,Q13144,P61086,P55212,Q9UIV1,Q06124,P28482,Q8TAT6,P00491,O95628,P45985,Q96BN8,P42574,Q9UHD2,O15347,O00203,P46109,Q00534,O75179,Q96FZ2,Q01804 57 +Astral microtubule organization 0.2494241190905144 0.0700802105323151 0.9441298176779128 1.0 1.0 5 Q7Z460 1 +Regulation of intracellular steroid hormone receptor signaling pathway 0.2014553257827984 0.0696287023763597 0.9444891911835028 1.0 1.0 27 Q96EB6,Q13153,Q9NUQ7,Q969T9,Q92600,P61960,Q15648,Q16512,Q86X55,Q13309,A5YKK6 11 +Developmental growth involved in morphogenesis 0.1926825077802322 0.0696119608419546 0.9445025166619304 1.0 1.0 43 Q9Y263,Q8N0X7,Q00535,P50570,P43034,O14965,Q93008,Q9P265,Q15648 9 +Head development 0.222694667709055 0.0693787299476383 0.9446881591597016 1.0 1.0 154 Q00535,Q9UQB8,Q9UID3,Q7Z460,P41240,O15020,P11413,Q96N67,P00492,P68036,P46379,P61960,Q15648,P31939,Q08209,P19784,P21359,Q66K74,O43776,Q13144,Q9BSJ2,Q05086,Q06124,P28482,P14854,O75569,O95487,P48444,P43034,O95456,Q15058,Q96P11,Q00534,P12277,P42574,O15067,Q15042,P27695 38 +Nucleoside triphosphate metabolic process 0.1866166467581574 0.0693059407090236 0.9447460971085524 1.0 1.0 46 P00813,P04075,Q9BY32,Q9BZX2,P15531,P00568,Q9Y3Z3,P33316,P17812,P12268,P20839,Q7Z2Z2,P27708,P22392,Q96DE0 15 +Circulatory system development 0.2265446999155961 0.0692083745667797 0.944823757153262 1.0 1.0 164 P11310,P55210,Q9Y696,Q92990,Q99956,Q9BQ70,Q9BXJ9,O75116,Q14999,P11413,P14618,P19174,P26358,Q96PU8,Q96AY3,Q15648,Q99873,Q96TA1,P40763,P78362,P21359,Q96EB6,Q9ULT8,Q14790,P20248,A1X283,Q06124,P13807,P28482,O95487,Q96BN8,Q6W2J9,Q9GZT9,Q92688,Q9NPQ8,O75179,P42574 37 +Regulation of cell cycle process 0.2016116076081848 0.0691647198685929 0.9448585052975138 1.0 1.0 202 Q9Y3I1,Q9Y295,Q96K76,P33981,P53350,Q69YH5,Q16539,Q99570,P42771,P18074,Q92547,Q96Q89,O75116,Q7L2J0,Q96DY7,P50748,O96017,P31350,Q14999,P23921,Q96DE0,Q9Y6G9,Q13619,O60566,Q9NR09,O14980,O43684,P11802,O95905,O60921,P61289,P39748,Q96RU2,Q15648,Q96BK5,P35241,P19784,Q96EB6,Q9H900,Q6Y7W6,Q9P258,Q15645,Q8IXJ6,O14965,Q13618,Q08J23,Q9UJX4,Q14203,P30307,Q06124,Q04637,Q13564,Q16513,Q7Z5K2,Q13535,Q7Z7L1,O94966,P43487,Q9H8V3,Q15058,O75351,O14744,O43264,O75179,Q14204,Q969U7,Q15398,P14635,P52732,P27695 70 +Positive regulation of protein kinase a signaling 0.5161194029850833 0.0691243998591484 0.9448905991987746 1.0 1.0 2 P14174 1 +Regulation of protein phosphorylation 0.2204010142263924 0.0689842110467496 0.9450021873164643 1.0 1.0 197 O00560,O00410,Q00535,P52564,P46940,O75116,Q13546,O60921,Q99627,P31751,P61086,Q96B36,Q9Y3I1,O95067,Q9UER7,Q92796,Q16512,O96017,P22681,Q99996,P51114,P47897,P67870,Q92974,Q8TEW0,P21359,Q13432,Q9UIV1,O95373,P42858,P46109,Q96JP5,P60510,P41440,P42771,Q96KB5,Q06787,Q9Y376,Q96N67,O43318,P51452,P31689,P51116,P49407,Q96EB6,Q8IXJ6,Q15334,P20248,P49327,Q06124,Q04637,Q13153,P07900,Q9H8V3,O75909,Q13501,P14635,P33981,P53350,P41240,Q92600,Q8WUA2,Q6PJG6,P36507,P22059,P08238,O75832,Q96AC1,Q9UII4,Q13526,Q13043,P30307,P28482,Q14012,Q99741,P35080,Q9NYV4,Q9UHD2,Q15058,P23381,P42574,P13010 82 +Cognition 0.2002459689822087 0.0688103350237146 0.9451405914297412 1.0 1.0 36 P21359,Q00535,P43034,P28482,Q96P11,P42858,Q05086,P39748,Q9NPQ8,P42574,P78559 11 +Regulation of cellular amide metabolic process 0.2187260389584568 0.0686723319737285 0.9452504420831892 1.0 1.0 196 P49770,Q9BX40,P61221,Q9C0B1,Q15056,Q92900,Q5TAX3,Q92600,Q6L8Q7,O75116,Q06787,P41567,Q7Z478,O60841,P14618,P26196,P62701,P27635,P62495,P46199,P51114,Q92499,P07814,O43432,Q96PU8,O15371,Q969T7,Q86TB9,P40763,P51116,Q9BY44,P78344,Q6Y7W6,Q13526,Q6PKG0,Q13464,Q567V2,P31751,Q8TEQ6,Q13144,Q5PRF9,Q9UIV1,P00374,P20248,O75534,P55010,P63241,P13639,Q04637,Q9HCE1,Q14240,Q92616,Q8IZH2,Q9Y2L1,P05198,Q04206,Q96C86,P42574,Q9BQC3,P06730,Q96P11,Q9Y450,O60573,P18669,P67809,A5YKK6,Q86W50,P21399,P27695 69 +Neuron development 0.2162428516848081 0.0677795471106968 0.9459611253549628 1.0 1.0 192 Q9Y3I1,P41440,Q00535,Q9UQB8,Q15555,Q6IBS0,Q96Q89,P78559,Q16512,Q06787,Q14999,O60701,O00401,Q9BPU6,Q96N67,P00492,P09429,P16949,Q9BTW9,Q99873,Q96TA1,Q08209,Q8TEW0,Q9BW83,Q9Y263,Q8N0X7,Q66K74,P10589,O14965,Q99707,Q9UL15,P00374,Q05086,O60678,O60493,Q9P265,Q06124,Q9HCE1,O95487,P50570,Q9H4M9,P43034,A0AVT1,Q93008,Q32P28,Q9UBB6,P42574,Q13614 48 +Positive regulation of fatty acid biosynthetic process 0.5137313432835908 0.0677004958827725 0.9460240545615052 1.0 1.0 2 Q92604 1 +Arachidonic acid secretion 0.5137313432835908 0.0677004958827725 0.9460240545615052 1.0 1.0 2 P14174 1 +Cell morphogenesis 0.2172207912629424 0.0673791421960529 0.9462798735642372 1.0 1.0 189 P47756,Q9Y696,P41440,Q00535,Q9UQB8,Q16539,Q6IBS0,Q96Q89,P78559,Q16512,Q9UL63,Q14999,O00401,Q9BPU6,P04075,Q96N67,P00492,P33176,P16949,Q9BTW9,P35241,Q15648,Q96AC1,Q96TA1,Q92974,Q08209,Q8TEW0,P35579,Q9Y263,Q8N0X7,Q9P258,Q66K74,O14965,Q13618,Q15334,Q14185,Q05086,O60678,Q14155,Q9P265,Q06124,Q9HCE1,Q9UPY3,O95487,P50570,Q13153,P43034,O60610,O60568,Q9H8V3,O00203,Q15058,Q15020,Q93008,P46109,P42574 56 +Histone mrna metabolic process 0.1729782482546992 0.0670073713329476 0.9465758349167142 1.0 1.0 12 Q5TAX3 1 +Mrna catabolic process 0.1946488069997637 0.0669732250382804 0.946603018653324 1.0 1.0 111 Q9Y2V2,Q9C0B1,Q16539,Q92900,Q5TAX3,Q13310,Q6PGP7,Q6L8Q7,O75116,Q06787,Q96F86,Q96DE0,P62495,P51114,Q969T7,Q86TB9,O00178,Q9UPR3,P51116,Q9HAU5,Q6Y7W6,Q6P2E9,Q6PKG0,Q13464,Q5PRF9,P05455,Q9UIV1,O75534,Q9HCE1,Q7L8L6,Q9Y2L1,Q96C86,Q6P6C2,Q15477,P67809,A5YKK6,Q86W50,P27695 38 +Regulation of multicellular organismal development 0.1620404776525246 0.0669164273171585 0.9466482352429296 1.0 1.0 193 Q9Y3I1,P00813,Q00535,Q9UQB8,Q7Z460,Q99956,Q16539,Q6IBS0,P22392,O75116,Q9H3U1,Q14999,P11413,Q96N67,P14618,P35611,P19174,P46379,Q15382,P09429,Q15648,Q99873,Q96TA1,Q08209,Q8TEW0,P40763,Q96EB6,P21359,Q8N0X7,Q14790,P20248,Q9P265,Q06124,Q9UIS9,P00491,O95628,P43034,Q6W2J9,Q9GZT9,O15347,O00203,Q15058,Q96P11,Q00534,O14744,P63172,Q13614,P27695 48 +Negative regulation of protein modification process 0.2082549593777367 0.0667994013123834 0.9467414000300376 1.0 1.0 133 Q9Y3I1,P60866,P31946,Q00535,Q92990,P42771,Q96KB5,O75116,Q16512,P22681,P11413,P62081,O60566,O43684,Q04323,P48506,P47897,P26358,Q96FW1,P51452,Q96BK5,P19474,P31689,Q8TEW0,P49407,Q96EB6,Q01105,P21359,Q9Y263,Q15257,Q8IXJ6,O95071,Q9UL15,O60678,Q96B36,O95373,Q6W2J9,P46109,Q32P28,Q13501,P42574,P62841,P60510 43 +Central nervous system development 0.2067170908103483 0.0662165363204036 0.9472054315881973 1.0 1.0 187 P49770,Q00535,Q9UQB8,Q9UID3,Q7Z460,P41240,P18074,O15020,P11413,Q96N67,P00492,P68036,P46379,Q15382,P61960,Q15648,P31939,Q08209,P40763,P19784,P21359,Q66K74,O43776,Q13144,Q9BSJ2,O00330,Q05086,Q06124,P28482,P14854,O75569,O95487,P48444,P43034,O95456,Q15058,Q96P11,Q00534,Q92688,O14744,P12277,P42574,Q15042,P27695 44 +Developmental cell growth 0.1840282319384479 0.0661158639685397 0.9472855808658438 1.0 1.0 46 P11413,Q9Y263,Q8N0X7,Q00535,P50570,P43034,O14965,Q93008,O95376,Q9P265 10 +Response to organic cyclic compound 0.1812379871251402 0.0660484242193371 0.9473392726404732 1.0 1.0 189 P55210,P41440,P63151,Q00535,Q9NUD5,Q9UER7,Q14258,O75116,Q16512,Q13309,P22681,P11413,O75874,Q99996,P68036,P11802,Q13126,Q92499,P07099,P26358,P61960,P40763,P49721,P40818,Q96EB6,Q15126,Q14790,Q6PKG0,O95071,P55212,P00374,Q05086,P20248,P28482,Q9NUQ7,O14744,P42574,P28161,P27695 39 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.5101492537313521 0.0656385858704748 0.9476655682563668 1.0 1.0 2 Q13177 1 +Positive regulation of deoxyribonuclease activity 0.5101492537313519 0.0656385858704746 0.947665568256367 1.0 1.0 2 P12004 1 +Regulation of axonogenesis 0.1951366589179085 0.0655228901446896 0.9477576817940574 1.0 1.0 26 Q16512,Q9P265 2 +Steroid hormone mediated signaling pathway 0.1931361637172929 0.065467107186177 0.9478020947962856 1.0 1.0 40 Q96EB6,Q9NUQ7,O95071,Q05086,Q9UER7,P61960,Q16512,Q13309 8 +Positive regulation of transcription by rna polymerase ii 0.1654104667405767 0.0653126733775767 0.9479250519939976 1.0 1.0 186 P53999,Q03164,Q6PL18,Q7L2J0,Q00653,P08237,Q96IU4,P09429,Q86TU7,P40763,Q08209,Q96EB6,P10589,Q8NCF5,Q05086,P20248,Q92616,P43490,O75569,Q92905,P18615,P35269,Q9Y2X0,Q13501,P67809,Q9Y613,P27695 27 +Response to hormone 0.1832300586770933 0.065163080412769 0.9480441561884784 1.0 1.0 185 P49770,Q9UQB8,P41240,Q9UER7,Q14258,O75116,Q16512,Q13309,O75874,Q15392,O60343,P14618,P09960,P68036,P11802,P61960,P67870,Q15648,P40763,P40818,Q96EB6,O15357,O95071,P31751,Q13144,O00330,Q05086,P20248,P07741,Q00796,Q06124,P43490,Q96T76,Q9NUQ7,Q9Y5X3,P42574,P27695 37 +Immune system development 0.2165589491798769 0.0651554403980227 0.9480502391113508 1.0 1.0 169 Q03164,Q9Y3I1,P00813,Q9Y3Z3,Q16539,Q9NPH0,O95067,Q13310,P18074,Q9H3U1,Q16512,O95394,Q9UQ84,Q00653,P11413,Q13619,O00625,P09429,P39019,Q15648,Q99873,P40763,P18858,Q96EB6,P21359,Q9ULT8,Q14790,Q99439,Q9Y4B6,P20585,O95376,P49327,P13639,Q06124,P52701,P28482,P62753,P24390,Q6IBW4,P00491,O95628,P43034,P42574,O15347,O00203,Q15020,P46109,Q00534,Q96FZ2 49 +Positive regulation of transport 0.1946649987315017 0.0649224822100946 0.9482357201386988 1.0 1.0 183 Q13614,Q03164,P41440,Q00535,Q7Z460,Q92614,Q96Q89,O14737,P78417,Q06787,P35754,P22681,P11413,Q99996,P08237,Q9Y6B6,P19174,P68036,O00429,P22059,Q08209,P19784,Q96EB6,Q9Y263,O95071,P31751,P55786,Q06124,Q9H4M9,Q9H8V3,Q9Y5K6,P42858,Q9Y5X3,P28161,Q15042,P27695 36 +Regulation of keratinocyte proliferation 0.2140508221225806 0.0649209190245467 0.9482369647546268 1.0 1.0 7 Q9Y3B8,Q6ZWJ1,P58107,O14936,P31947,Q15648 6 +Keratinocyte proliferation 0.2140508221225806 0.0649209190245467 0.9482369647546268 1.0 1.0 7 Q9Y3B8,Q6ZWJ1,P58107,O14936,P31947,Q15648 6 +Negative regulation of cellular component organization 0.1930848330068018 0.0646686065622604 0.9484378588163902 1.0 1.0 182 O00560,P47756,Q13614,Q00535,P33981,P53350,Q7Z460,Q7Z6Z7,P60953,Q9H6U6,P50395,Q6IBS0,O75116,Q96DY7,P50748,P47755,Q9Y6G9,O15020,O00401,O60566,Q96QK1,O60343,P35611,O15344,O43684,P48506,O75832,P09429,P16949,Q9BTW9,Q96BK5,P35241,P29372,Q92974,Q08209,O43683,Q9H900,Q8N0X7,Q9P258,Q13464,Q13045,Q8IXJ6,Q15645,P10589,P60983,Q9UL15,Q15334,P04350,Q13432,Q05086,Q9UEY8,Q14155,Q99471,Q9P265,Q8IZH2,Q7Z5K2,P07737,Q9NRR5,P50570,P43034,Q15058,P13010,O43264,P35080,Q969U7,Q15691,P14635,Q9BPX3 68 +Branching morphogenesis of an epithelial tube 0.1778355397452604 0.0645535589955217 0.9485294620907618 1.0 1.0 16 Q9Y696,Q13153,Q13043,Q15648,Q16512 5 +Endosome to lysosome transport via multivesicular body sorting pathway 0.3257688862346901 0.0644318208250197 0.9486263933043088 1.0 1.0 3 O75351,P55072 2 +Establishment of protein localization to mitochondrial membrane 0.1773453883033351 0.0643156150323316 0.9487189201987716 1.0 1.0 16 Q9P0J0 1 +Srp dependent cotranslational protein targeting to membrane signal sequence recognition 0.5077611940298596 0.0643123804319891 0.948721495704414 1.0 1.0 2 P09132 1 +Multi organism reproductive process 0.2128655313005484 0.0642110552828039 0.9488021747196808 1.0 1.0 155 Q9Y696,P41440,P00813,P11172,P46926,P17655,Q8NHU6,O95067,Q15056,Q5TAX3,Q9H6S0,O95394,Q14353,P04075,Q14997,P46379,Q96CW5,P25440,Q96PU8,Q14157,Q15648,Q96SB4,P40763,P19784,Q9BW83,Q96EB6,P47914,P35579,P49368,Q15645,O14965,Q08J23,Q05086,P30307,P52701,P62753,P17987,Q7Z7E8,Q6IBW4,P50570,P43034,Q6P6C2,O00203,Q93008,P46109,Q15003,P48643 47 +Organophosphate biosynthetic process 0.2123584495640454 0.0640136379624194 0.948959367557022 1.0 1.0 166 Q13614,P00813,P11172,Q8NCE2,P17655,Q9NPH0,Q99570,P27708,P22392,O96017,P31350,O60256,P23921,P11413,O75874,Q06203,P30520,P04075,Q96PE3,P00492,P33316,P22059,P53396,P31939,O00154,Q9HCL2,Q15126,O15357,O96007,O00330,P20839,Q08AM6,Q01433,P07741,P04183,Q13057,P43490,Q9BZX2,P15531,P35790,P17812,Q9NVE7,P06737,P12277,P30566,P42356,P53602,O15067 48 +Actin filament based process 0.1578969807871418 0.0639273762028777 0.9490280537994428 1.0 1.0 180 P47756,Q00535,Q9UQB8,Q7Z460,Q9H6U6,Q96IZ0,Q6IBS0,Q92614,O75116,Q16512,Q9UL63,P47755,P57737,O15020,O00401,Q99996,P04075,Q9UH99,P35611,P16949,P35241,Q96AC1,Q86TU7,Q92974,P60981,P49407,P21359,P35579,O15357,Q99439,Q13618,Q15334,Q9UEY8,Q9Y490,Q13153,P43034,O60610,Q9H8V3,Q9Y5K6,P35080,P07737,Q9Y613,P15311,Q9BPX3 44 +Histone modification 0.2124317762822667 0.0638826274250406 0.949063685327164 1.0 1.0 162 O75182,Q03164,Q9BV86,Q00535,Q16512,Q06787,Q9H4L7,Q99504,O14929,O43318,P26358,Q96FW1,Q86TU7,Q99873,Q96EB6,Q01105,Q9UPT9,Q7LBC6,O14965,O95071,P20248,Q99986,Q6W2J9,P18615,Q15020,O14744,Q5VTR2 27 +Leukocyte chemotaxis 0.1947196773375196 0.0638780365988832 0.9490673408104028 1.0 1.0 29 P09429,P30046,Q92538,O00429 4 +Axon extension 0.1924226401539724 0.0637830936650944 0.949142940145687 1.0 1.0 26 P78344,Q00535,P50570,P43034,P07900,Q6IBS0,Q93008,P08238,Q9P265 9 +Organic cyclic compound catabolic process 0.1890264701424966 0.0637169028969549 0.949195645529774 1.0 1.0 178 P00813,Q9Y2V2,P53004,Q9Y3Z3,Q9C0B1,Q5TAX3,Q13310,Q96HR8,O75116,Q06787,Q96F86,Q8WTV0,Q9BPU6,P00492,P62495,P33316,P51114,Q13126,P39748,Q8IYS1,Q969T7,Q86TB9,Q9UPR3,Q9HAU5,Q9NRN7,O00154,Q6Y7W6,Q6P2E9,Q6PKG0,Q08J23,P05455,Q9UIV1,O75534,Q9HCE1,Q7L8L6,Q9Y2L1,P26572,Q9H814,Q9BY32,Q96C86,P30519,Q6P6C2,Q9UKK9,Q99575,Q15477,P67809,Q86W50,P27695 48 +Organelle localization 0.1758823450812487 0.0635303657351395 0.9493441797158162 1.0 1.0 178 Q8NCA5,P15311,Q00535,O75153,P61221,P53350,Q7Z460,Q9H0B6,Q9BUK6,Q9UBF2,P22681,O00743,O00401,Q99996,Q96N67,P63104,Q9UH99,Q9Y6B6,O14980,O15027,O00429,P33176,Q96BK5,Q8TEW0,Q99661,P35579,Q66K74,Q9Y2T2,Q13618,Q15334,Q14203,Q96GA3,Q9UIS9,Q9HC35,Q9NR31,P48444,P50570,Q92734,P43034,Q92538,Q9NZ32,Q92905,O00203,Q15058,P42858,Q96D46,P63172,O75351,Q8TD16,O43264,Q15398,Q14204,P62841,Q9Y613,P14635,P27695 56 +Developmental process involved in reproduction 0.2094033463215538 0.0632793973440326 0.949544021416106 1.0 1.0 150 P49770,P00813,Q8NHU6,Q5TAX3,Q9H6S0,O95394,Q14353,Q14999,P22681,Q15392,O75874,Q9NR09,Q14997,P46379,Q96PU8,Q15648,Q96SB4,P19784,Q9BW83,Q96EB6,Q9ULT8,Q14790,Q15645,O14965,Q08J23,Q13144,Q05086,P20248,O75534,P30307,P52701,Q06124,P62753,P28482,P50570,Q6P6C2,P42574 37 +Positive regulation of dna biosynthetic process 0.19443461240739 0.0630606662071769 0.9497181957486684 1.0 1.0 32 P49368,Q9BRX5,Q99832,P07900,P50991,Q9BUR4,P40227,P08238,Q96HR8,P28482,P17987,Q9BRT9,P13010,P48643,Q13535 15 +Negative regulation of catalytic activity 0.2092125215623313 0.0630306948514837 0.9497420619522884 1.0 1.0 161 Q9Y3I1,P60866,P31946,O00170,Q96K76,P61221,Q9H6U6,P41240,P42771,O75116,Q16512,O60256,P22681,P27544,P62081,Q15392,Q99996,O60566,Q9NR09,Q9Y314,O43684,Q04323,P47897,P51452,Q86VP6,Q96BK5,P35241,P31689,Q96EB6,Q01105,Q9C0C9,P21359,Q9P258,Q15257,Q9Y570,Q9UL15,P61201,Q14240,P30086,Q96B36,O95373,P36404,Q9GZT9,P42574,P62841,Q9BTT0 46 +Rac protein signal transduction 0.1694415979227555 0.0629664204047339 0.9497932438742812 1.0 1.0 14 P21359 1 +Cellular nitrogen compound catabolic process 0.1920377645929969 0.0625712716535462 0.9501079064750648 1.0 1.0 172 P00813,Q9Y2V2,P53004,Q9Y3Z3,Q9C0B1,Q5TAX3,Q13310,Q96HR8,O75116,Q06787,Q96F86,Q9BPU6,P00492,P62495,P33316,P51114,Q13126,P39748,Q8IYS1,Q969T7,Q86TB9,Q9UPR3,Q9HAU5,Q9NRN7,O00154,Q6Y7W6,Q6P2E9,Q6PKG0,Q08J23,P05455,Q9UIV1,O75534,Q9HCE1,Q7L8L6,Q9Y2L1,P26572,Q9H814,Q9BY32,Q96C86,P30519,Q6P6C2,Q9UKK9,Q99575,Q15477,P67809,Q86W50,P27695 47 +Microtubule based transport 0.1564774790718432 0.0621786401167001 0.9504205722881092 1.0 1.0 55 Q9BW83,Q66K74,Q9NZ32,P43034,P27695,Q9Y2T2,O00203,P42858,Q14203,Q8TD16,Q9UBF2,P33176,Q14204,P78559,Q9UIS9,O60333 16 +Transition metal ion homeostasis 0.1870008521292164 0.0619659147451598 0.9505899759095398 1.0 1.0 24 Q9H3K6,O75880,Q9Y487,P30519,O00203,O60826,P21399 7 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.2538829151732303 0.0619322975520923 0.9506167471297022 1.0 1.0 4 Q8IXJ6,O95817,P25685 3 +Establishment of organelle localization 0.2022345601394643 0.0615226709002112 0.9509429598350244 1.0 1.0 139 P15311,Q00535,P61221,Q7Z460,Q9UBF2,P22681,O00743,O00401,Q96N67,P63104,Q9UH99,Q9Y6B6,O14980,O15027,P33176,Q96BK5,Q8TEW0,Q99661,P35579,Q66K74,Q9Y2T2,Q13618,Q15334,Q14203,Q96GA3,Q9UIS9,Q9HC35,Q9NR31,Q92538,P50570,Q92734,P43034,Q9NZ32,Q92905,O00203,Q15058,P42858,Q96D46,P63172,O75351,Q8TD16,O43264,Q15398,Q14204,P62841,Q9Y613,P14635,P27695 48 +Exocytosis 0.1619272633413355 0.0614089204851048 0.951033548249734 1.0 1.0 73 Q4J6C6,Q00535,Q92905,Q16512,P27695,Q7Z392,Q7Z460,P35080,Q06787,Q9Y6D5,Q15042,P22681 12 +Regulation of binding 0.1795938816257225 0.0614007643551552 0.9510400436427288 1.0 1.0 97 P41440,Q00535,P53350,P60953,P18074,Q7L2J0,Q06787,Q86X55,O14981,P35611,P08238,P09429,P67870,P16949,Q96BK5,P19474,O15371,Q96TA1,Q08209,Q13526,Q13464,Q13043,Q8IXJ6,O14965,O00330,Q14155,Q04637,P14735,Q7Z5K2,Q14012,P05198,P15531,P35269,Q96D46,P17612,Q15691 36 +Tube development 0.2020894936365912 0.0611261480222357 0.9512587449727624 1.0 1.0 142 Q9Y696,P00813,Q92990,Q9H6U6,Q16539,Q9BXJ9,Q96Q89,O75116,Q16512,Q14999,Q13572,Q9HCK8,P62081,P63104,P14618,P09960,P19174,P46379,P25440,Q96PU8,P67870,Q96AY3,Q15648,Q96TA1,P40763,P78362,P21359,Q96EB6,Q9ULT8,Q14790,O00330,P20248,P28482,O95487,P11586,Q96BN8,Q9GZT9,O60568,O00203,P46109,P42574 41 +Positive regulation of organelle organization 0.1962382765646092 0.0610538111479269 0.9513163538498302 1.0 1.0 162 Q9Y3I1,Q9Y295,Q00535,Q9BPX3,Q9UQB8,Q7Z460,Q9H6U6,Q15555,O14737,Q96HR8,O75116,Q16512,P27544,O00401,Q14008,Q99996,O00429,P22059,P26358,P39748,Q96AC1,P60981,P49368,Q8IXJ6,O14965,Q13618,P31751,Q9UJX4,Q14203,Q13283,Q9NTJ3,P28482,P17987,Q13535,Q15691,P35080,Q13153,P36404,O95347,P42858,O75351,Q15021,Q15003,Q15398,A5YKK6,Q14204,P07737,Q9Y613,Q15042,P48643,P27695 51 +Anatomical structure formation involved in morphogenesis 0.1785541548325282 0.0606970348334678 0.9516004931890136 1.0 1.0 165 Q9Y696,P41440,P00813,Q00535,Q92990,P17655,Q7Z460,Q96C57,P18074,Q9BXJ9,Q96Q89,O75116,Q16512,Q00653,P62081,P14618,P19174,Q15648,Q96TA1,P40763,P78362,P21359,Q96EB6,Q9ULT8,Q14790,P20248,Q06124,P28482,O95487,Q9H4M9,Q96BN8,P43034,Q9GZT9,P42574,Q13614 35 +Positive regulation of embryonic development 0.1920537990238114 0.0606449154013674 0.951642002012544 1.0 1.0 8 Q96TA1 1 +Cell activation 0.1993546148537957 0.0603322638562609 0.9518910058989823 1.0 1.0 139 Q9Y3I1,P00813,Q92990,P41240,Q96IZ0,Q16539,Q92614,Q16512,Q9UQ84,P22681,O00299,Q00653,P00492,P46379,P48506,P12268,P09429,P51452,Q08209,P40763,Q9ULT8,Q9HCL2,Q14790,Q9Y4B6,P52701,Q06124,P62753,P24390,Q6IBW4,P00491,Q92538,P42574,Q9UHD2,O15347,O00203,P17812,Q00534,O14744,Q96FZ2,P48507 40 +Regulation of cellular component movement 0.1936409322172037 0.0603310299688634 0.9518919886085722 1.0 1.0 159 P00813,Q00535,Q15555,Q96Q89,O75116,Q16512,Q8WTV0,Q99996,Q96N67,Q9UH99,P19174,P57076,O00429,P30046,P09429,P67870,P16949,Q96AC1,Q08209,P40763,Q96EB6,P21359,Q9Y263,P31751,Q14185,P20248,Q14155,P28482,Q15058,Q00534,Q5VTR2,P35080,P27695 33 +Response to cytokine 0.1859859815909649 0.0603261751805851 0.9518958551266052 1.0 1.0 162 Q04727,Q9P0J0,P17655,Q9Y3Z3,Q16539,Q14694,P48507,Q14258,Q9H6S0,P22681,O15111,Q14166,P49427,P11802,P07814,P48506,P10155,O43318,P12268,P67870,P19474,Q15648,Q92974,P31939,P40763,Q9Y5A7,Q96EB6,Q14790,P61086,O00330,Q9UIV1,P63241,P49327,Q06124,P28482,P51858,Q96BN8,P43034,Q9UHD2,P39023,P46109,Q01813,P42574,P67809,Q01804 45 +Organ growth 0.1850280924311778 0.0603141628517651 0.9519054221575384 1.0 1.0 25 Q05086,Q99956,Q06124 3 +Glycosphingolipid biosynthetic process 0.3180053747387209 0.060307858709881 0.9519104429952652 1.0 1.0 3 Q99805,Q13131 2 +Secretion 0.1981246461318906 0.0602766695260814 0.9519352831734508 1.0 1.0 154 P00813,P11172,Q00535,Q7Z392,Q7Z460,Q96KP1,P20645,Q9UBF2,Q92614,Q16512,Q06787,Q9Y6D5,P22681,P08237,O00429,P17858,P22059,Q15648,Q96TA1,Q08209,P21359,Q4J6C6,O00330,P07741,Q06124,P61201,Q7Z7E8,Q92905,P43034,P15531,Q9Y5K6,Q8TAG9,Q9Y5X3,P35080,Q15042,P27695 36 +Positive regulation of protein binding 0.1831553309835788 0.0600633452265038 0.952105183503559 1.0 1.0 24 P41440,Q13526,Q00535,P35611,Q96D46,P08238,P19474,P14735,Q15691 9 +Antigen processing and presentation via mhc class ib 0.3173133997309957 0.0599648606322043 0.9521836214588308 1.0 1.0 3 O00203 1 +Transport along microtubule 0.158067424766009 0.0598919599250098 0.9522416834515546 1.0 1.0 54 Q9BW83,Q66K74,Q9NZ32,P43034,P27695,Q9Y2T2,O00203,P42858,Q14203,Q8TD16,Q9UBF2,P33176,Q14204,P78559,Q9UIS9,O60333 16 +Gamete generation 0.1841113960322177 0.0597564729491108 0.9523495931438664 1.0 1.0 107 Q8NHU6,O95067,Q5TAX3,Q9H6S0,O95394,Q14353,Q14997,P46379,Q96PU8,Q96SB4,P19784,Q9BW83,Q96EB6,Q15645,O14965,Q08J23,P30307,P52701,P62753,Q6IBW4,P50570,P43034,Q6P6C2 23 +Regulation of cell division 0.1881219476899946 0.0597300616247321 0.9523706287575338 1.0 1.0 38 Q99741,Q13526,Q9NR09,P53350,O14965,Q8IXJ6,Q13618,Q9H8V3,Q15058,Q99570,Q96Q89,P67809,Q16513 13 +Response to lipid 0.1903576087583799 0.0597074614040277 0.9523886289986654 1.0 1.0 157 Q9P0J0,P17655,Q9UER7,Q14258,O75116,Q16512,P22681,Q8WTV0,P68036,Q13126,P61960,P09429,P40763,P40818,Q96EB6,Q9Y263,Q15126,Q14790,Q05086 19 +Transferrin transport 0.2499999999999919 0.0594301414209627 0.952609506098198 1.0 1.0 4 Q00610,P50570,Q07960 3 +Cellular response to reactive oxygen species 0.1884193928448685 0.0594245768261435 0.952613938169402 1.0 1.0 31 Q96EB6,Q9NX46,Q9H8V3,Q96IZ0,P00374,P28482,P27695 7 +Regulation of anatomical structure morphogenesis 0.1771726621554276 0.0593899706861205 0.95264150119325 1.0 1.0 159 P00813,Q00535,Q9UQB8,Q7Z460,Q7Z6Z7,O75116,Q16512,Q9UL63,Q14999,P14618,P19174,O00429,Q96AC1,Q96TA1,Q08209,P40763,Q96EB6,P21359,Q9Y263,Q8N0X7,Q9P258,O14965,Q14185,Q05086,Q14155,Q9P265,O95487,P50570,Q9GZT9 29 +Endoplasmic reticulum to golgi vesicle mediated transport 0.1543790102997947 0.0587652728040404 0.953139068925546 1.0 1.0 66 P53621,P53992,Q7Z392,Q9UBF2,O00743,Q9HD26,Q9Y6B6,O15027,Q15436,O95486,Q13618,Q96JB2,Q96RQ1,O95487,P24390,P53618,Q9NR31,P48444,Q92734,Q92538,Q9Y678,O95070,O43264,P35606,O94979 25 +Positive regulation of immune system process 0.1897793180315985 0.0587202011926563 0.95317496887479 1.0 1.0 121 P49770,P00813,Q9NUD5,P41240,Q96IZ0,Q92614,Q9NW08,Q16512,Q9BUI4,P19174,O00429,P46379,Q92499,O43318,P09429,Q15648,Q96EB6,Q9HCL2,Q14790,Q13144,P55212,Q06124,P28482,Q9UHD2,O75179,Q96FZ2 26 +Positive regulation of wnt signaling pathway 0.175899457265411 0.0584060105284713 0.9534252272379816 1.0 1.0 22 P40818,Q96K76 2 +Regulation of immune response 0.1927602215612849 0.0583509824320509 0.9534690585532156 1.0 1.0 133 P49770,P41440,P00813,Q9NUD5,P41240,Q9Y3Z3,Q96IZ0,Q16539,Q14232,Q14258,P25786,Q9NW08,Q16512,Q14166,Q9BUI4,P19174,P46379,O43318,P09429,P39019,P51452,P19474,Q15648,P28070,Q96EB6,Q14790,Q13144,P61086,P55212,Q9UIV1,Q06124,P28482,Q8TAT6,Q9NR50,P45985,Q96BN8,Q13153,P07900,Q9UHD2,O00203,P46109,O75179,Q96FZ2,Q01804 44 +Negative regulation of cellular protein catabolic process 0.1862584590285447 0.0582471189421346 0.9535517889175612 1.0 1.0 31 O00560,P62081,Q96QK1,O94966,Q04323,P46379,P68400,Q9UL15,P08238,Q9Y5K5,Q96KB5,P62829,O43765,P78559,P19784 15 +Cellular response to starvation 0.1869758184476763 0.0582126688797385 0.9535792295292838 1.0 1.0 35 Q96EB6,Q9P2J5,Q9Y4P8,Q99570,P08243,P49327,P28482,Q92616,O95352 9 +Innate immune response 0.192328787548929 0.0581530893926652 0.9536266866870224 1.0 1.0 134 Q9NUD5,Q9Y3Z3,Q14258,Q9NW08,Q16512,Q13309,O15111,O00743,Q14166,Q9BUI4,O14802,P07814,Q92499,O43318,P33176,P39019,P09429,P19474,Q15648,Q92974,Q96SB4,Q9Y5A7,P78362,Q9UII4,Q14790,Q8IXJ6,P61086,P55212,Q9UIV1,Q13283,P07437,Q06124,O95801,O95373,Q8IWZ3,Q96BN8,Q13153,Q9UHD2,O15347,O75179,Q01804 41 +Nuclear transcribed mrna catabolic process nonsense mediated decay 0.1621876380696595 0.0577576893450297 0.953941640895547 1.0 1.0 17 Q9UPR3,Q15477,Q9HAU5 3 +Histone h2b ubiquitination 0.204006475532259 0.0576416989369029 0.9540340339232988 1.0 1.0 7 Q5VTR2,Q9NW82,O75150 3 +Developmental growth 0.1854274047201196 0.057550894660912 0.9541063651801418 1.0 1.0 116 Q9Y696,Q00535,Q99956,Q9C0B1,P18074,Q14353,O15020,P11413,P11802,Q7Z4V5,Q15648,Q08209,P40763,Q9Y263,Q9HCL2,Q8N0X7,O14965,Q05086,O95376,Q9P265,Q06124,P61201,P50570,P43034,Q93008,Q9BRT9 26 +Chondrocyte differentiation 0.1657194137002661 0.0574042137843631 0.9542232064248956 1.0 1.0 9 O95747,Q92896,P35222,P16435,Q16539,Q9C0E8,Q06124,P50454 8 +Positive regulation of behavior 0.3114362496267489 0.0572065887514612 0.954380629693052 1.0 1.0 3 Q92769,Q96QK1 2 +Regulation of dna metabolic process 0.1766908396308114 0.057163481468818 0.9544149681368452 1.0 1.0 148 P53999,Q03164,Q9BUR4,P18074,Q96HR8,P27544,Q9H4L7,Q99504,P09429,Q7Z4V5,Q96FW1,Q96EB6,O95071,P20585,P52701,P28482,Q13535,Q96T76,Q96FZ2,Q01804 20 +Positive regulation of telomere maintenance 0.1801155502253397 0.0569951236824953 0.9545490795663856 1.0 1.0 27 P49368,Q99832,P50991,P40227,Q96HR8,P28482,P17987,P13010,P48643,Q13535 10 +Vesicle budding from membrane 0.1845610577931647 0.056874668879612 0.9546450329473256 1.0 1.0 36 O00743,O00401,Q9NR31,Q92538,Q92734,O15027,Q9Y6B6,Q13618,Q15436,O00203,O94979,Q92614,O60493,O14617,O95487 15 +Purine containing compound metabolic process 0.1790730602543231 0.0567733081587203 0.9547257766369732 1.0 1.0 145 P00813,Q9Y3Z3,Q86TX2,P85037,P22392,O60256,O60725,Q06203,P30520,P04075,P09972,P08237,P14618,P00492,Q13126,P17858,P53396,Q96IU4,P31939,P40763,Q9P2T1,O00154,Q9HCL2,Q15126,Q9UKG9,O00330,P20839,Q01433,P07741,Q13057,P51570,Q9BY32,P36404,P15531,P53602,Q9NVE7,P30566,P18669,O15067 39 +Multicellular organism reproduction 0.1869352492668876 0.05674490301101 0.954748404187992 1.0 1.0 126 P00813,Q8NHU6,O95067,Q5TAX3,Q9H6S0,O95394,Q14353,Q14997,P46379,Q96PU8,Q15648,Q96SB4,P19784,Q9BW83,Q96EB6,Q15645,O14965,Q08J23,P30307,P52701,Q06124,P62753,Q7Z7E8,Q6IBW4,P50570,P43034,Q6P6C2,P42574 28 +Chromosome segregation 0.1846870894439533 0.0566666250336411 0.9548107606419822 1.0 1.0 140 Q9BV86,O95239,P33981,P53350,Q9HBM1,P60953,Q69YH5,Q9BTE3,P42695,Q8TD19,P18074,Q9GZZ1,Q6P1K2,P50748,Q9Y6G9,Q9H4L7,O76071,O60566,O43684,P46379,P39748,Q96BK5,Q96SB4,Q99661,P19784,O43683,Q9H900,Q9P258,Q15645,Q8IXJ6,Q13618,Q9UJX4,Q8IX90,Q9NTJ3,Q29RF7,Q7Z5K2,Q6IBW4,Q99741,Q9HC35,Q96T76,Q9UJX5,Q9H8V3,O95347,Q15058,Q93008,O75351,Q15021,Q15003,O43264,Q14204,Q969U7,Q15398,P14635,Q9BPX3 54 +Regulation of neuron differentiation 0.1660592926916415 0.0566144908984499 0.954852290992224 1.0 1.0 20 P26196,P06730,Q9H8V3,Q04637,Q15648,Q92974 6 +Positive regulation of cell differentiation 0.1851023799738884 0.0565289306269349 0.9549204490594312 1.0 1.0 138 O00560,P00813,Q9UQB8,P60953,Q16539,Q6IBS0,P22392,Q9H3U1,Q13546,Q86X55,O96017,Q7L576,Q14999,O43809,O00299,Q9UGN5,P35611,Q13418,P08238,Q15382,P09429,Q96AC1,Q15648,Q86TU7,Q96TA1,Q92974,P40763,O14617,Q99873,Q96EB6,P78344,Q14790,Q13043,P61160,P55209,Q8IXJ6,O14965,Q14185,P20248,Q14155,Q04637,Q9UPY3,Q14012,P00491,P50570,Q9UQ80,P43034,Q9H8V3,O00203,P46109,O14744,P13010,P27695 53 +Response to catecholamine 0.1596011594316674 0.0563565099493679 0.955057801893508 1.0 1.0 18 P50570,Q96QK1,Q8IXJ6,O14744,P17612,P28482 6 +Regulation of cell activation 0.1542820789158382 0.0559078743477846 0.9554151978210444 1.0 1.0 69 Q9Y3I1,P00813,P00491,Q9HCL2,P42574,Q92990,P41240,O15347,Q96IZ0,P48506,Q92614,P09429,Q06124,Q96FZ2,Q16512 15 +Regulation of dna replication 0.1736059534512696 0.0558827774502724 0.9554351909914798 1.0 1.0 46 Q9UBD5,Q7Z7L1,P20248,Q7Z5K2,Q13535 5 +Dna templated transcription initiation 0.1790749826519506 0.0557995636653658 0.9555014825486984 1.0 1.0 42 P53999,P29083,Q15369,P11802,Q9Y2X0,P35269,P09429,Q86VP6 8 +Central nervous system neuron differentiation 0.1530360968119964 0.0556391273163959 0.9556292936762044 1.0 1.0 17 Q6Y7W6,Q00535,P43034,P07900,P00492 5 +Mitotic nuclear division 0.182792653031713 0.0554475248372934 0.9557819347007268 1.0 1.0 128 Q9Y295,Q6NUK4,P33981,P52732,Q7Z460,P60953,Q9H6H4,Q69YH5,P53350,P42695,O95239,Q9GZZ1,Q96Q89,Q96DY7,O96017,P50748,Q14999,Q9Y6G9,O60566,O43684,Q96BK5,Q99661,O43683,Q9H900,Q13526,Q15645,P83731,Q8IXJ6,O14965,Q13618,Q9UJX4,P30307,Q9NTJ3,Q29RF7,Q6IBW4,Q99741,Q9HC35,P43487,Q9UJX5,O95347,Q15058,O75351,O14744,Q15021,Q15003,O43264,Q969U7,Q15398,P14635,Q9BPX3,Q16763 51 +Rna catabolic process 0.1798712129605675 0.0551761777954361 0.955998107382884 1.0 1.0 133 Q9Y2V2,Q9C0B1,Q16539,Q92900,Q5TAX3,Q13310,Q96HR8,Q6L8Q7,O75116,Q6PGP7,Q06787,Q96F86,P62495,P51114,P39748,Q969T7,Q86TB9,Q9UPR3,P51116,Q9HAU5,Q6Y7W6,Q6P2E9,Q6PKG0,Q08J23,Q5PRF9,P05455,Q9UIV1,O75534,Q9HCE1,Q9UPY3,Q7L8L6,Q9Y2L1,Q9H814,Q96C86,Q6P6C2,Q99575,O75792,Q15477,P67809,A5YKK6,Q86W50,P27695 42 +Cellular response to inorganic substance 0.178792883519449 0.0549833411752166 0.9561517355308478 1.0 1.0 41 Q9Y696,P50570,P35611,Q99707,Q9H8V3,P20248,Q9UER7,P28482,Q06787,O15111 10 +Fibroblast growth factor receptor signaling pathway 0.1809210526315811 0.0548481294189546 0.9562594563521178 1.0 1.0 8 Q9UQ13,P35222,Q9Y639,Q8NEM2,P46940,P46109,Q06124 7 +Cellular response to organic cyclic compound 0.1790545569653619 0.0545432447811405 0.956502355493899 1.0 1.0 127 P55210,P41440,Q9NUD5,Q9UER7,O75116,Q16512,Q13309,Q99996,P68036,P11802,P26358,P61960,P40818,Q96EB6,Q6PKG0,Q14790,O95071,P55212,Q05086,P20248,P28482,Q9NUQ7,O14744,P42574,P28161,P27695 26 +Fear response 0.3048006195154621 0.0544109587028543 0.9566077480076476 1.0 1.0 3 Q04637 1 +Endocytosis 0.1770266317295702 0.0539347719852432 0.956987132935132 1.0 1.0 116 P41440,P20645,Q92614,Q06787,Q9UL63,P22681,Q8WTV0,O00429,Q96D71,Q08209,Q96T51,O15357,Q14185,Q13432,Q05086,P28482,Q9H4M9,Q7Z3T8,P15531,Q9Y5K6,Q9Y5X3,Q13614,Q14677 23 +Regulation of extrinsic apoptotic signaling pathway 0.1781785802868835 0.0535868115167691 0.9572643642994882 1.0 1.0 36 P42858,P21359,Q99504,Q9NR09 4 +Golgi vesicle transport 0.1731926922327204 0.0534056898853785 0.9574086718116536 1.0 1.0 126 Q9UID3,Q7Z392,P41240,Q96KP1,Q7Z3U7,Q92614,Q9UBF2,O60826,Q9Y6D5,P57737,O00743,Q9Y6B6,Q4J6C6,Q96JB2,O60493,O95487,P24390,P53618,P48444,P50570,Q92734,Q92538,Q14746,Q8TAG9,P42858,Q8TD16,Q9UJY4,O95070 28 +Positive regulation of cell cell adhesion 0.1733220161215143 0.0524774063842159 0.9581482976177484 1.0 1.0 32 P41440,P00813,P00491,Q9HCL2,P41240,P09429,Q06124 7 +Regulation of telomere maintenance via telomere lengthening 0.1704956538103572 0.0523291160161876 0.9582664538668336 1.0 1.0 30 P49368,Q99832,P50991,P40227,P13010,Q96HR8,Q8IZH2,Q96BK5,P28482,P17987,Q9UPR3,P48643,Q13535 13 +Positive regulation of cell growth 0.1747983288523091 0.0521793290176125 0.9583858035466396 1.0 1.0 39 O00560,P78344,Q9UGN5,Q9Y263,Q96K76,P43034,P60953,Q6IBS0,O75832,Q6PJG6,Q7Z4V5,Q04637 12 +Mammary gland duct morphogenesis 0.2979994028068015 0.0518727176175311 0.9586301131868202 1.0 1.0 3 Q15648,Q14160 2 +Positive regulation of protein localization to nucleus 0.1738283833453686 0.0517359981748803 0.9587390532403206 1.0 1.0 39 P49368,O00410,Q96AC1,P53350,P50991,O95071,Q9Y5K6,Q16539,Q96BK5,P40227,Q9H8V3,Q96D46,P08238,Q7L2J0,P17987,P48643 16 +Vesicle mediated transport in synapse 0.1731969464673796 0.051678704312318 0.9587847060580384 1.0 1.0 35 Q4J6C6,Q9Y263,Q00535,Q96QK1,P50570,O00203,P35080,O14617,Q06787,P54920,Q15042 11 +Mitotic dna integrity checkpoint signaling 0.1559280934301164 0.0505487674302145 0.9596850882589872 1.0 1.0 27 Q99741,Q9NXR7,Q6Y7W6,P53350,P43246,Q92547,O60921,Q13564,O96017 9 +Microtubule cytoskeleton organization involved in mitosis 0.1514050197913491 0.0501951430948177 0.9599668819258778 1.0 1.0 74 Q9Y295,P33981,Q7Z460,Q9HBM1,Q15813,O96017,Q14008,Q9UH99,P16949,Q15257,O14965,Q14203,P43034,P42858,P63172,O75351,O43264,Q14204,Q15398,P14635,P52732 21 +Positive regulation of secretion 0.1607949456041927 0.0493726306995249 0.9606223390910906 1.0 1.0 48 Q00535,P08237,Q7Z460,Q9Y5K6,O00429,P22059,Q9Y5X3,Q92614,Q06124,Q15042 10 +Positive regulation of protein modification by small protein conjugation or removal 0.1620039885050742 0.0480503312004556 0.9616761304051182 1.0 1.0 45 Q9UBT2,P68036,Q15020,Q05086,Q5VTR2,Q13309,Q16763 7 +Regulation of chromosome organization 0.1467766478608912 0.0473562182885459 0.9622293225889412 1.0 1.0 104 P33981,P53350,Q92900,Q96HR8,P33993,P50748,Q9Y6G9,Q9H1A4,O60566,O43684,P26358,P39748,O14777,Q96BK5,Q9UPR3,O43683,P49368,Q9H900,P49736,Q15645,P50991,P49750,Q13618,P40227,Q9UJX4,Q9NTJ3,Q8IZH2,Q9Y5K5,P28482,P17987,Q7Z5K2,Q13535,Q99741,Q99832,Q9UJX5,O95347,P13010,Q15021,Q15003,O43264,Q15554,Q969U7,Q15398,P14635,Q9BPX3,P48643 46 +Viral genome replication 0.1537208011994101 0.0472963662205171 0.9622770241795376 1.0 1.0 50 O75116,P78362 2 +Regulation of signal transduction by p53 class mediator 0.1588903713919274 0.0472601647251986 0.9623058765298198 1.0 1.0 37 Q96EB6,P62081,P60866,O14965,P63241,Q13535 6 +Detoxification of nitrogen compound 0.2798652939358264 0.0465342646591146 0.9628844244083276 1.0 1.0 3 P28161 1 +Transcription elongation from rna polymerase ii promoter 0.1376883642302078 0.0461879550626447 0.9631604426974822 1.0 1.0 33 Q6IA86,Q8IXH7,P18615,P35269,O75909,P13984,Q9Y5B9,Q16186 8 +Neuron projection extension 0.150154363396917 0.045802266103313 0.9634678526189024 1.0 1.0 37 Q9Y263,P50570,Q00535,P43034,O14965,Q93008,Q9P265 7 +Regulation of dna biosynthetic process 0.1529692509300682 0.0455670975704195 0.9636552942541614 1.0 1.0 48 Q9BUR4,Q96HR8,P27544,P08238,Q96BK5,Q96TA1,Q9UPR3,P49368,P50991,P40227,Q8IZH2,P28482,P17987,Q13535,Q99832,P07900,P13010,Q9BRT9,P48643 19 +Positive regulation of dna metabolic process 0.1291240753694257 0.0437128287371268 0.9651333131388424 1.0 1.0 90 Q96EB6,Q99504,Q9BUR4,P18074,P09429,Q7Z4V5,Q96HR8,Q96FZ2,P28482,Q13535,Q01804 11 +Regulation of organelle assembly 0.1341614579654041 0.043354299509594 0.9654191071299364 1.0 1.0 63 O00560,Q9Y295,P15311,P53350,Q9NT62,P50395,Q15555,P26038,Q16181,Q8WUM4,Q9NZN8,Q9UHD8,Q6UVJ0,Q9Y3P9,Q92597,P35241,P0DMV9,Q13283,Q8TBX8,Q16658,Q96C92,P50570,Q9NVG8,Q99816,P42858,O75351,Q15042,Q14204,A5YKK6,Q8TC07,Q9BPX3,P27695 32 +Regulation of telomere maintenance 0.1227619154259561 0.0424457180604982 0.9661433834258256 1.0 1.0 41 P49368,Q99832,P50991,P49750,P48643,Q92900,P40227,P13010,Q96HR8,Q8IZH2,Q96BK5,P28482,P17987,Q15554,Q9UPR3,Q93009,Q13535 17 +Negative regulation of homotypic cell cell adhesion 0.2521609166086168 0.0415414889488355 0.9668642179861826 1.0 1.0 3 P35241 1 +Negative regulation of execution phase of apoptosis 0.4116417910447854 0.035559163612624 0.9716338704292488 1.0 1.0 2 Q13177 1 +Meiotic cytokinesis 0.407761194029861 0.0351093548370797 0.9719925419311908 1.0 1.0 2 P61160 1 +Columnar cuboidal epithelial cell maturation 0.4035820895522465 0.034662921289386 0.9723485276725304 1.0 1.0 2 P04818 1 +Regulation of lipopolysaccharide mediated signaling pathway 0.3913432835820973 0.0335594706138203 0.973228441814141 1.0 1.0 2 P14174 1 +Positive regulation of leukocyte adhesion to vascular endothelial cell 0.3865671641791134 0.0332023580482688 0.9735132177101268 1.0 1.0 2 Q04206 1 +Regulation of leukocyte adhesion to vascular endothelial cell 0.3865671641791134 0.0332023580482688 0.9735132177101268 1.0 1.0 2 Q04206 1 +Heat acclimation 0.382686567164185 0.0329391531536058 0.9737231100229382 1.0 1.0 2 P0DMV9 1 +Plasma membrane to endosome transport 0.3710447761194111 0.0322781052959981 0.9742502695480196 1.0 1.0 2 P61020 1 +Polyamine biosynthetic process 0.3680597014925459 0.0321362998207217 0.9743633552799372 1.0 1.0 2 P19623 1 +Spermidine metabolic process 0.3561194029850824 0.0316642004324025 0.9747398444782136 1.0 1.0 2 P19623 1 +Neural plate development 0.3394029850746313 0.0312096247313296 0.9751023642290158 1.0 1.0 2 Q9HCM4 1 +Foregut morphogenesis 0.3394029850746313 0.0312096247313296 0.9751023642290158 1.0 1.0 2 Q9HCM4 1 +Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.3259701492537361 0.0309721318103571 0.9752917646001452 1.0 1.0 2 P61254 1 +Retinal ganglion cell axon guidance 0.3041791044776174 0.0307460828127228 0.9754720397479056 1.0 1.0 2 P83731 1 +Positive regulation of receptor clustering 0.2662686567164243 0.0306003359749159 0.9755882742072616 1.0 1.0 2 Q15334 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0921ee899cb04e1ce25c8b260acf8fd7f7a175e6 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B 1 b cell differentiation", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle myoblast proliferation", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac vascular smooth muscle cell differentiation", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Dipeptide transmembrane transport", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G1 to g0 transition involved in cell differentiation", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isg15 protein conjugation", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L kynurenine metabolic process", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of torc1 signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide import across plasma membrane", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic a cell differentiation", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper 17 cell differentiation", "Positive regulation of t helper 17 type immune response", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride lipase activity", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of antimicrobial humoral response", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell division", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 17 cell differentiation", "Regulation of t helper 17 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to pheromone", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sinoatrial node development", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell antigen processing and presentation", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transforming growth factor beta2 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRK1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPK", "CENPV", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NEMP1", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLE4", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512B", "ZNF598", "ZNF638", "ZNF703", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "ABCE1", "ABCF1", "ABHD10", "ABHD14B", "ACADM", "ACLY", "ACO1", "ACOT1", "ACOT7", "ACP6", "ACTN1", "ACTR10", "ACTR2", "ADA", "ADD1", "ADD3", "ADH5", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AHCY", "AIFM1", "AIMP2", "AIP", "AK1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH7A1", "ALDOA", "ALDOC", "ALG12", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "AP1M1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "APRT", "ARCN1", "ARFGAP1", "ARFGEF2", "ARG2", "ARHGAP1", "ARHGEF2", "ARHGEF7", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARMC8", "ARMT1", "ARRB1", "ARVCF", "AS3MT", "ASCC3", "ASNS", "ATAD2", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATR", "AURKA", "B4GAT1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BBS9", "BCAS3", "BCCIP", "BCOR", "BDH2", "BICD2", "BIRC6", "BLVRA", "BOLA2*", "BPNT1", "BRAT1", "BRD2", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "C12orf43", "C1QBP", "C21orf59", "CAB39", "CAD", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAPN1", "CAPN2", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CBL", "CCDC124", "CCDC22", "CCDC51", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CD2AP", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC6", "CDCA2", "CDH2", "CDK1", "CDK12", "CDK4", "CDK5", "CDK6", "CDKN2A", "CERS1", "CFL2", "CHAC2", "CHD1", "CHD1L", "CHD3", "CHD7", "CHD8", "CHEK2", "CHKA", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHUK", "CIAO1", "CKAP5", "CKB", "CLASP1", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLPP", "CLTC", "CLUH", "CMPK1", "CMTR1", "CNN2", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG7", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1A", "CORO1B", "CORO7", "COX6B1", "CPNE1", "CRKL", "CROT", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTH", "CTNNB1", "CTPS1", "CTR9", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL5", "CUL7", "CYFIP1", "CYP51A1", "DAXX", "DCAF1", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN3", "DCTPP1", "DDA1", "DDRGK1", "DDT", "DDX1", "DDX28", "DDX3X", "DDX6", "DENR", "DFFA", "DHCR24", "DHFR", "DHX29", "DHX36", "DIAPH1", "DICER1", "DIP2B", "DIS3", "DLG1", "DLG3", "DLGAP5", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSP", "DST", "DSTN", "DUS1L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLT1", "ECD", "ECT2", "EDC3", "EDC4", "EEF1A2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGLN1", "EHD1", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF3A", "EIF3D", "EIF3G", "EIF3I", "EIF3L", "EIF4A1", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELOC", "ELP1", "ELP2", "EML4", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "ERBIN", "ERCC2", "ERCC6L", "ERGIC2", "ETF1", "EXO1", "EXOC2", "EXOC6", "EXOC7", "EYA3", "EZR", "FAF1", "FAH", "FAM120B", "FAM129B", "FAM98A", "FANCD2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBXO7", "FEN1", "FERMT2", "FHOD1", "FKBP10", "FLAD1", "FLII", "FMR1", "FOXK1", "FRA10AC1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FXR1", "FXR2", "G3BP1", "G6PD", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAMT", "GAPVD1", "GARS", "GART", "GATA6", "GBF1", "GCLC", "GCLM", "GCN1", "GDI2", "GEMIN5", "GET4", "GFPT1", "GGA2", "GIGYF2", "GINS3", "GINS4", "GLG1", "GLMN", "GLRX", "GLRX3", "GMFB", "GMPR2", "GMPS", "GNL1", "GNPDA1", "GOLPH3", "GOLT1B", "GOPC", "GOT1", "GPAM", "GPHN", "GPI", "GRB2", "GSPT1", "GSTM2", "GSTM3", "GSTO1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTPBP1", "GYG1", "GYS1", "HAT1", "HAUS6", "HAUS8", "HBS1L", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HEATR3", "HECTD1", "HELLS", "HELZ", "HERC5", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPD", "HOXA10", "HOXD11", "HPRT1", "HSD17B10", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA2", "HSPH1", "HTT", "HUS1", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGHMBP2", "ILK", "IMPACT", "IMPDH1", "IMPDH2", "INPP4A", "INPPL1", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "IST1", "ITPA", "ITPK1", "KDELC2", "KDELR1", "KDM3B", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF1B", "KIF20B", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA4", "LARP1", "LARP7", "LARS", "LARS2", "LCMT2", "LDHA", "LEMD2", "LGALS3", "LIG1", "LLGL1", "LNPK", "LPGAT1", "LRBA", "LSM14B", "LSS", "LTA4H", "LTN1", "LTV1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARS", "MAT2B", "MBD1", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MED1", "MED16", "MEPCE", "MESD", "METAP2", "METTL1", "METTL16", "MGAT1", "MGEA5", "MIA3", "MID1", "MIF", "MIPEP", "MKLN1", "MMAB", "MMS19", "MOCS1", "MOCS2", "MON2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPV17L2", "MRPL47", "MRPL55", "MRRF", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTAP", "MTBP", "MTHFD1", "MTIF2", "MTMR14", "MTMR2", "MTOR", "MTR", "MVD", "MYCBP2", "MYG1", "MYH9", "MYO18A", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAPA", "NARS", "NARS2", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NCDN", "NCKAP1", "NCKIPSD", "NDC80", "NDRG1", "NDUFA13", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NIPSNAP1", "NIT2", "NMD3", "NME1", "NME2", "NOSIP", "NPEPPS", "NPLOC4", "NPTN", "NR2F1", "NRDC", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C3B", "NT5DC1", "NTMT1", "NUB1", "NUBP2", "NUCB2", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUTF2", "OCRL", "ORC3", "OSBP", "OSBPL6", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXSR1", "P3H1", "P4HA1", "PA2G4", "PABPC1", "PABPC4", "PAFAH1B1", "PAK1", "PAK2", "PALD1", "PANK4", "PARD3", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBK", "PCM1", "PCNA", "PCYOX1", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE4DIP", "PDHX", "PDLIM5", "PDS5A", "PDXK", "PEBP1", "PFAS", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGK1", "PGLS", "PGM1", "PGM3", "PGP", "PHAX", "PHF6", "PHKB", "PI4K2A", "PI4KA", "PIAS1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD3", "PLS1", "PM20D2", "PMF1", "PMPCA", "PMS1", "PMVK", "PNP", "POLD1", "POLD2", "POLE", "POLR3A", "POLR3B", "POLR3C", "POP1", "POR", "PPA2", "PPAT", "PPIE", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPP1CA", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP6C", "PPP6R3", "PPWD1", "PRC1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPS2", "PRPSAP2", "PRRC2C", "PSAT1", "PSMA1", "PSMA2", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMC1", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD10", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME3", "PSME4", "PSMG1", "PSMG2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPN11", "PUDP", "PUS1", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "RAB3GAP1", "RAB5B", "RABGAP1", "RAC1", "RACK1", "RAD50", "RAD54B", "RALGAPB", "RANBP1", "RANBP9", "RAPGEF2", "RARS", "RBPJ", "RCC2", "RCN1", "RDX", "RECQL", "REEP3", "REEP4", "RELA", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFK", "RHEB", "RHOA", "RHOG", "RIC8A", "RIPK1", "RMDN3", "RNASEH2A", "RNF20", "RNF40", "RNGTT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL13", "RPL14", "RPL15", "RPL17", "RPL18A", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL29", "RPL3", "RPL31", "RPL32", "RPL34", "RPL35", "RPL37A", "RPL4", "RPL5", "RPL6", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP40", "RPRD1A", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS29", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RTFDC1", "RUFY1", "SAE1", "SAMD4B", "SAMHD1", "SAR1A", "SAR1B", "SARS", "SART3", "SASS6", "SCARB1", "SCO1", "SCRIB", "SDCBP", "SDCCAG3", "SEC16A", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61G", "SEPHS1", "SEPT10", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD3", "SFN", "SGTA", "SH3PXD2B", "SHCBP1", "SHOC2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKP2", "SLC12A7", "SLC19A1", "SLC25A20", "SLC25A26", "SLC25A32", "SLC2A1", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIT2", "SLK", "SMARCAD1", "SMC2", "SMC4", "SMG5", "SMS", "SNX17", "SNX3", "SNX5", "SNX9", "SORD", "SPAG9", "SPART", "SPC25", "SPTBN2", "SQSTM1", "SRM", "SRP19", "SRPK1", "SRPK2", "SRRT", "SRXN1", "SSB", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STXBP4", "SUB1", "SUN2", "SUPT16H", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCD", "TBCE", "TBK1", "TCF25", "TCP1", "TDP1", "TDRD7", "TELO2", "TERF2", "TERF2IP", "TFG", "TFIP11", "THOP1", "THUMPD3", "TIMM17B", 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0.3162812394838912 0.0002484775908529 0.0020083404757072 0.0004026692559945 0.0015706126808535 +Transcription factor tfiid complex 3 9 2.239813597513237 0.0251030267470566 2.283980582524272 6.456310679611651 0.219490506438474 0.5288231791546844 1.6143878817163706 2.0751731663811745 0.9075709120088816 0.2987950320748276 1.0 1.0 0.1702739325736192 0.0612536211646263 +Peptidase complex 29 61 2.2357622968806843 0.0253673458752943 15.75242718446602 59.86893203883495 0.5096924099132711 0.6119855012565802 7.368712981381447 4.1374803346545495 1.0677911950970993 0.3642445397432887 0.067020455608496 0.0002211996802752 0.0003528980710654 1.680673497717812e-06 +Ubiquitin ligase complex 34 67 2.1476858344709227 0.031738721440514 15.37135922330097 61.429611650485434 -0.0248059945812641 0.7068340308999228 6.472905073787162 10.703297597508683 0.7731724737631867 0.3083588235187657 0.6995928214598932 0.4373321772249867 0.7445598362945507 0.3673773251636798 +Cytoplasmic microtubule 14 21 2.122626258366026 0.0337851827822519 5.655339805825243 19.983009708737864 0.0145703763593394 0.7086503797505646 2.9793212283369814 2.519285356731866 0.6152839633010482 0.266930194250954 0.2356515416958359 0.4231831300186898 0.4080060847317363 0.3103471330794518 +F actin capping protein complex 3 6 2.0795523667416487 0.0375666098744726 2.878640776699029 6.021844660194175 -0.4885700977289128 0.5162581484363276 1.545375216663904 0.6624524127592226 0.8085143334548255 0.307695033809423 1.0 1.0 1.0 1.0 +Proteasome core complex beta subunit complex 4 7 2.070979650175905 0.0383606978193356 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 0.0816476539699214 0.1966693812600725 0.0005688349419973 +Excitatory synapse 1 5 2.014404596200678 0.0439670722032858 1.305825242718447 5.067961165048544 0.7953512276346466 0.4272224812891962 1.179791428227925 0.8869292057247719 0.8699509292644302 0.3159178070156055 0.0670021260054199 0.1323778037089543 0.0491545726752397 0.1630814235328921 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7f14676b2b61628fe430311db72a09b2d47ac7e3 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 906, + "title": "Average number of proteins per term", + "value": 29.248344370860927 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8b58b38bb4f5826422b2c60abbb81c0989aa9fbf --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7a96fa4ca6f1eb79c88fa585615908598d0609a3 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,294 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Dna polymerase complex 0.8140782547027651 3.0500098834593334 0.0022883383559229 0.8745201770428334 0.1480881821761536 10 P28340,P25205,P49005,Q07864 4 +Replisome 0.781953757277679 2.8995064802981414 0.0037375061910318 0.9663763084904684 0.211636288067179 11 P28340,P25205,P49005,P35244 4 +Endopeptidase complex 0.457442101116867 2.5340200347551307 0.0112762284441791 0.999965491335964 0.3570582856490842 52 P62191,P60900,P43686,P17655,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,Q8IWV7,O43396,Q15386,P28070,P49721,Q05086,Q9Y5K5,Q16186,Q5VYK3,P28074,P62195,Q13200 28 +Ruffle 0.3981634860729602 2.530590440728009 0.0113870724173281 0.9999688244303412 0.3570582856490842 57 Q9UQB8,Q8NCE2,P46940,P22392,Q16512,Q9UL63,Q7L576,P19174,Q92974,P35579,Q13464,P31751,Q14155,Q9Y490,P50570,Q13153,O60610,P15531,Q9Y5K6,Q9Y5X3,Q00534,P15311,Q9BPX3 23 +Proteasome complex 0.4968754139619063 2.5025367939546235 0.0123306807785386 0.9999868756984788 0.3570582856490842 48 P62191,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,Q8IWV7,O43396,Q15386,P28070,P49721,Q05086,Q9Y5K5,Q16186,Q5VYK3,P28074,P62195,Q13200 28 +Microtubule associated complex 0.4542212432738662 2.3929289794823 0.0167144761166304 0.9999997667837696 0.3570582856490842 51 Q9H0B6,Q15555,Q9BT25,Q96Q89,P78559,Q9Y6G9,O60333,O15344,Q96S59,P33176,P29372,Q99661,Q66K74,Q7Z4H7,O14965,Q14203,Q96P70,O43237,Q9NZ32,P43034,O75935,Q14204,Q15058,P63172,P52732 25 +Cytosolic ribosome 0.4107394014051742 2.3151049718650474 0.0206071880052691 0.9999999935884571 0.3570582856490842 79 P46776,P84098,P62750,P60866,P62917,P62906,P61254,P61247,P50914,P46778,P36578,Q7Z478,P62081,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P39019,P62269,P61513,P51116,Q9BY44,P47914,P83731,P05387,P62753,P18621,P62899,P15880,P05198,P39023,P62266,P46783,P62841 37 +Ficolin 1 rich granule lumen 0.3976272413086578 2.28893195496207 0.0220833062598493 0.999999998365123 0.3570582856490842 71 Q7Z6Z7,Q15008,Q16539,P22392,P20618,P25787,O00487,Q9Y376,O75874,P04075,P09972,P14618,P09960,O43242,P28066,P17858,P53396,P12268,P09429,P67870,Q86VP6,P20839,P13639,P28482,Q9UNP9,O95352,P46976,P00491,Q9NZ32,P07900,P06737,P63172,P18669,Q13200 34 +Proteasome core complex 0.659444372567592 2.2808392855415582 0.0225579587501973 0.9999999989469248 0.3570582856490842 14 P60900,O14818,P28066,P49720,P20618,P28074,P25786,P25787,P28070,P49721 10 +Magnesium dependent protein serine threonine phosphatase complex 0.6596229096954407 2.264978801683553 0.0235139803969508 0.9999999995660668 0.3570582856490842 10 Q8TF05,P63151,Q15257,P30154,Q14738,Q08209 6 +Nuclear replication fork 0.6529735644854591 2.2620926049407184 0.0236916824070749 0.99999999963203 0.3570582856490842 16 P28340,Q9H4L7,P35244,P25205,P49005 5 +Transcription factor tfiid complex 0.6857038526164765 2.239813597513237 0.0251030267470566 0.9999999999007794 0.3570582856490842 9 P18074,Q92759,P35269 3 +Peptidase complex 0.3792141511121769 2.2357622968806843 0.0253673458752943 0.9999999999223916 0.3570582856490842 61 P62191,P60900,P43686,P17655,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,Q8IWV7,O43396,Q15386,P28070,P49721,Q9UPT9,Q05086,Q9Y5K5,Q16186,Q5VYK3,P28074,P62195,Q13200 29 +Ubiquitin ligase complex 0.3802693431478578 2.1476858344709227 0.031738721440514 0.9999999999997962 0.3734452159104638 67 Q9Y3I1,Q15369,Q96K76,Q92990,Q93034,Q9NT62,Q9UL63,Q13309,Q14999,Q13616,Q9H1A4,Q9NXR7,Q13619,O60566,P68036,Q96S59,Q8IWV7,Q86VP6,P61962,Q13617,Q5TAQ9,Q9Y4B6,Q13618,Q9UJX4,O95376,Q96P70,Q8IUR7,O75150,Q9UJX5,Q6W2J9,Q96BN8,Q9BW61,Q5VTR2,Q16763 34 +Cytoplasmic microtubule 0.6173990393377711 2.122626258366026 0.0337851827822519 0.99999999999997 0.3902374087387523 21 Q6NUK4,P13693,P43034,Q7Z460,Q9H6U6,Q9H6H4,Q15555,Q9BSJ2,P63172,Q14204,P29372,Q15691,Q9Y6D5,Q99661 14 +F actin capping protein complex 0.7408120530057924 2.0795523667416487 0.0375666098744726 0.9999999999999992 0.3902374087387523 6 P35611,P47755,Q9BPX3 3 +Proteasome core complex beta subunit complex 0.7104986127137164 2.070979650175905 0.0383606978193356 0.9999999999999996 0.3902374087387523 7 P28074,P28070,P49721,P49720 4 +Excitatory synapse 0.7647078516608506 2.014404596200678 0.0439670722032858 1.0 0.4020909397567775 5 Q9UQB8 1 +Alpha dna polymerase primase complex 0.8034217918688742 2.012999458974672 0.0441146862710204 1.0 0.4020909397567775 4 P25205 1 +Protein phosphatase type 2a complex 0.7426339911471271 1.9165055776841555 0.0553007739288755 1.0 0.4275158361942865 5 Q14738,P63151,Q15257 3 +Dna replication preinitiation complex 0.5944150938665542 1.9119785385514312 0.055878946844337 1.0 0.4275158361942865 10 P25205 1 +Proteasome core complex alpha subunit complex 0.6770740026826286 1.911346516776024 0.0559600649129063 1.0 0.4275158361942865 7 P60900,O14818,P28066,P25786,P25787 5 +Transcription factor tfiih holo complex 0.7748225694118025 1.8903710577234232 0.0587083514099378 1.0 0.4275158361942865 4 P18074,Q92759 2 +Eukaryotic translation initiation factor 2b complex 0.6986309258608209 1.8859845983844872 0.0592970301492044 1.0 0.4275158361942865 6 P49770,P05198,Q14232,Q13144 4 +Scf ubiquitin ligase complex 0.6430464072450129 1.8775923890009245 0.0604369477252064 1.0 0.4275158361942865 8 Q13616,Q9Y3I1,Q96K76,Q93034,Q13617,Q13309 6 +Cyclin dependent protein kinase holoenzyme complex 0.5852883684622566 1.865758031316397 0.0620752265230886 1.0 0.4275158361942865 14 Q00535,P49736,Q9NYV4,P11802,O75909,O95067,Q00534,P20248,P14635 9 +Trna methyltransferase complex 0.6933999476271693 1.8617321196915968 0.062640858765947 1.0 0.4275158361942865 6 P57081,Q9UJA5 2 +Pole plasm 0.6902841061769229 1.8472612822502568 0.0647092814646099 1.0 0.4275158361942865 6 P42694,Q8NHU6,Q9Y2V2 3 +Proteasome regulatory particle 0.5760624686735426 1.8382424738530347 0.0660266836331706 1.0 0.4303609738967814 18 P62191,O00487,P43686,P48556,P62333,Q99460,Q13200,O43242,Q15008,O00231,P51665,P55036,Q9UNM6,P62195,Q16186,P35998 16 +Cop9 signalosome 0.6034759898270247 1.8127718526854215 0.0698670169704036 1.0 0.4406347666197309 9 Q7L5N1,Q92905,P19174,P61201,Q99627 5 +Copi vesicle coat 0.5987722947627547 1.7878376021545204 0.0738022123235278 1.0 0.448988193450638 9 P53618,P48444,P53621,Q9Y678,P61923,Q9UBF2,P35606 7 +Proteasome accessory complex 0.561072286523988 1.7819074581160683 0.0747643241206821 1.0 0.448988193450638 21 P62191,P43686,P48556,P62333,Q16186,Q99460,O43242,Q15008,O00231,P51665,P55036,P61289,Q9UNM6,P62195,O00487,P35998,Q13200 17 +Proteasome regulatory particle base subcomplex 0.592581513610528 1.7549464637868872 0.0792684655165127 1.0 0.4525055505614471 9 P62191,P43686,P62333,Q99460,P55036,P35998,P62195,Q13200 8 +Nucleocytoplasmic transport complex 0.5907915247725279 1.7454211399494908 0.0809115885109872 1.0 0.4525055505614471 9 Q9HAV4 1 +Presynaptic cytosol 0.701608262427894 1.7323150284993176 0.0832174876164928 1.0 0.4576667529473132 5 Q9UQB8 1 +Dendritic shaft 0.7014438312119946 1.7315713815269564 0.0833499053380868 1.0 0.4576667529473132 5 Q9UQB8 1 +Transferase complex transferring phosphorus containing groups 0.3707069147835495 1.7172173769418893 0.0859394616957023 1.0 0.4690430861223271 87 P29083,Q00535,P49643,P25205,O95067,Q99570,P18074,Q96P16,Q9NW08,P49005,O60256,O15111,Q9Y376,Q93100,Q9BUI4,O14802,P08237,P11802,P17858,P11908,P13984,O00443,Q8TEW0,P49642,Q14558,P28340,Q92759,P20248,Q08AM6,Q96T76,Q9Y4A5,Q9NYV4,P35269,Q07864,O15160,Q00534,O75909,Q01813,P14635 39 +Ccr4 not complex 0.6563520532401503 1.6885364815768786 0.0913082920528627 1.0 0.4822931733309788 6 Q9UIV1,Q92600,O95628,A5YKK6 4 +Cul2 ring ubiquitin ligase complex 0.7280420798769296 1.6871048278495857 0.0915831969011959 1.0 0.4822931733309788 4 Q92990,Q15369 2 +N terminal protein acetyltransferase complex 0.7280188194696342 1.687003018571104 0.0916027715328087 1.0 0.4822931733309788 4 Q5VZE5,Q14CX7 2 +Neuron to neuron synapse 0.3355214756685621 1.669212184473437 0.0950753362137359 1.0 0.489400050291165 63 P47756,Q00535,P62917,Q9UQB8,Q06787,Q9Y6D5,Q14152,Q99996,Q96PE3,P63104,P35611,P51114,Q15382,P39019,P62269,P51116,P40818,Q9UEY8,P50570,Q13614 20 +Extrinsic component of endosome membrane 0.7103509516644906 1.609487314708642 0.1075098265823342 1.0 0.5082073650428444 4 Q9Y5X3,P40818 2 +Mismatch repair complex 0.7099761051373881 1.6078389272856126 0.1078704603964988 1.0 0.5082073650428444 4 P54277,P20585,P52701 3 +Pericentriolar material 0.7089925377020785 1.6035129851749366 0.1088214446118231 1.0 0.5082073650428444 4 P17987,Q3SYG4 2 +Annulate lamellae 0.6719888680863296 1.5977493608683873 0.1100987685678509 1.0 0.5100831370901235 5 Q9Y5L0,P63241,Q8TD16 3 +Platelet alpha granule lumen 0.5341034074116395 1.5756084136062491 0.1151160759379203 1.0 0.5169713809191333 10 Q8NBX0 1 +Aminoacyl trna synthetase multienzyme complex 0.5336321526131208 1.5698550342020323 0.1164488406913424 1.0 0.5171698513056678 11 Q9P2J5,P14868,P07814,P47897,P41252,Q13155,P54136 7 +Cytosolic large ribosomal subunit 0.4118054178809573 1.5643057603081996 0.1177457800105532 1.0 0.5178527994638895 46 P46776,P84098,P62750,P62917,P62906,P61254,P50914,P46778,P36578,Q02543,P32969,P27635,P42766,P61513,P51116,P47914,P83731,P05387,P18621,P62899,P39023 21 +Carboxy terminal domain protein kinase complex 0.5809632360181126 1.5610573195063573 0.1185102271589311 1.0 0.5186969362608289 8 Q96T76,P18074,Q92759,O75909 4 +Death inducing signaling complex 0.6573367333993309 1.5307798543306548 0.1258238101687658 1.0 0.537797818240178 5 P49327,Q14790 2 +Chaperonin containing t complex 0.5730108939582609 1.520044051847889 0.1284999044896051 1.0 0.5418473452060247 8 P49368,Q99832,P50991,P40227,P17987,P48643 6 +Elongator holoenzyme complex 0.6899865586069911 1.5197351442546203 0.1285775550400756 1.0 0.5418473452060247 4 Q6IA86,O95163 2 +Polysome 0.383435247241785 1.509263464384219 0.1312314674835255 1.0 0.5432026608657923 49 P84098,Q9Y295,Q00341,P62917,P60900,P25786,Q06787,P62701,P51114,P62854,Q9HAU5,P51116,Q6PKG0,P83731,Q04637,P13639,P62753,Q92616,P62899,P05198,P62266,P20290 22 +Lipid droplet 0.4914950966046126 1.5025878919915048 0.1329453476096371 1.0 0.5432026608657923 30 Q01105,Q92538,Q8N0X7,Q9H4M9,Q9H6V9,Q8NBX0,P48449,Q15042 8 +Smn complex 0.6492074684477994 1.4935294213582422 0.1352986587521911 1.0 0.5440329633546602 5 Q9Y3F4,Q8TEQ6,Q16637 3 +Trna splicing ligase complex 0.6143685822644888 1.4896796807156962 0.1363084797809137 1.0 0.5440329633546602 6 Q8NCA5 1 +Ccr4 not core complex 0.6824970131421695 1.4866359470844652 0.1371109883120624 1.0 0.5445551171082137 4 Q9UIV1,A5YKK6,Q92600 3 +Ribonuclease p complex 0.5893116023257066 1.4819208541111817 0.138361355440675 1.0 0.5445551171082137 7 O15091 1 +Proteasome regulatory particle lid subcomplex 0.5865670266720481 1.4683083549051223 0.1420204824918554 1.0 0.5537200433667946 7 O00487,O43242,O00231,Q9UNM6,Q16186 5 +Phagocytic cup 0.641876301122871 1.4598866549479024 0.1443212274789611 1.0 0.5564043918976119 5 Q9Y5X3 1 +Ciliary transition zone 0.6069934249850804 1.4545292963289065 0.145799617256594 1.0 0.5564861163995073 6 Q9UIS9,Q15555,P36405,Q15019,Q3SYG4 5 +Messenger ribonucleoprotein complex 0.6392784381430155 1.447955059568171 0.1476296195115409 1.0 0.5573018136560671 5 P67809 1 +Condensin complex 0.5538783947377324 1.4210747348337778 0.1552950340607402 1.0 0.5610657983535868 8 Q6IBW4,P42695,Q15021,Q15003,Q9NTJ3,Q9BPX3 6 +Cul4 ring e3 ubiquitin ligase complex 0.5285866200128054 1.4109500387776697 0.158259346146226 1.0 0.5610657983535868 9 Q13619,Q5TAQ9,Q92990,Q9Y4B6,P61962 5 +Ciliary membrane 0.5976678206891568 1.4100153572242178 0.1585351483206603 1.0 0.5610657983535868 6 Q3SYG4 1 +Postsynaptic cytosol 0.5947900606843686 1.3962659651445049 0.1626344188230284 1.0 0.5689064998210955 6 Q9UQB8 1 +Rnai effector complex 0.54850584713269 1.393225473186166 0.1635516190611721 1.0 0.5699144879593151 8 Q9HAV4,P26196,Q9UPY3 3 +Replication fork 0.4540559274620677 1.381409637155374 0.1671530444016791 1.0 0.5781272335345318 35 P28340,P41440,Q9H4L7,P35244,P25205,P26358,Q96FZ2,P49005 8 +Ficolin 1 rich granule 0.343340927766733 1.3767749007514876 0.1685818531272533 1.0 0.5781272335345318 88 Q5T4S7,Q7Z6Z7,Q15008,Q16539,Q93050,P22392,P20618,P25787,O00487,Q9Y376,Q9Y6G9,O75874,P04075,P09972,P14618,P09960,O43242,P28066,P17858,P53396,P12268,P08238,P09429,P67870,Q86VP6,P36871,P20839,P13639,P28482,Q9UNP9,O95352,P46976,P53618,P00491,Q9NZ32,P07900,O60610,P04080,P06737,P63172,P18669,Q13200 42 +Rna polymerase iii complex 0.5881036705085807 1.3643003510543483 0.1724730554689792 1.0 0.580894380129722 6 Q9NW08,Q9BUI4,O14802 3 +Microtubule 0.3974222420995985 1.3580418335961162 0.1744504102793191 1.0 0.5836382599371422 137 P68371,Q00535,Q9UQB8,Q6NUK4,P53350,Q7Z460,Q9H6U6,Q9H6H4,Q9H0B6,Q15555,P46940,Q9BT25,Q9BUF5,Q15813,O94967,Q96Q89,Q92598,P78559,P50748,Q9Y6D5,Q14152,O60333,Q9Y6G9,Q14008,P13693,O15344,P36507,Q9UHD8,O00429,Q96CW5,P33176,P16949,Q9BTW9,Q96TC7,P29372,O75347,Q92974,O94927,Q99661,P49368,Q66K74,Q9P258,Q99426,Q7Z4H7,Q8IXJ6,P50991,Q13618,O14965,Q86TI2,Q9BSJ2,P40227,Q14203,P04350,P07437,Q8IX90,Q8WWK9,O43237,P17987,Q9HC35,Q99832,P50570,P43034,Q03001,Q15058,P63172,Q00610,O43264,Q13885,Q14204,Q5SW79,Q15691,O95239,P52732,P48643 74 +Cullin ring ubiquitin ligase complex 0.454990249464631 1.3561294538325228 0.175057982924397 1.0 0.5836382599371422 34 Q9Y3I1,Q15369,Q96K76,Q92990,Q93034,Q13309,Q14999,Q13616,Q9H1A4,Q13619,O60566,Q86VP6,P61962,Q13617,Q5TAQ9,Q9Y4B6,Q13618,Q9UJX4,Q9UJX5,Q9BW61,Q16763 21 +Perinuclear endoplasmic reticulum 0.5862886594970218 1.355619335846426 0.1752203164491199 1.0 0.5836382599371422 6 P17655,Q9BZF3 2 +Vesicle tethering complex 0.4897053866317382 1.350474777120385 0.1768637390073961 1.0 0.5838935643938585 22 Q9UID3,Q7Z392,Q14746,Q96JB2,Q96KP1,Q9H269 6 +Nucleolar ribonuclease p complex 0.7866255964204846 1.3468137777388631 0.1780402162389704 1.0 0.5844363620018379 3 O75818 1 +Kinesin complex 0.4935362719484319 1.3363086688117742 0.181448404234084 1.0 0.5902316629653243 16 P43034,Q9H0B6,Q15058,Q99661,Q96Q89,P52732,O60333 7 +Cd95 death inducing signaling complex 0.7801157172702478 1.3215966818533065 0.1863024889045583 1.0 0.6011355728196677 3 Q14790 1 +Filopodium tip 0.6109949208246216 1.3178174358711896 0.1875647697031359 1.0 0.6011355728196677 5 Q06787,Q9H4L5,Q7L576,P61086 4 +Saga type complex 0.4881438325063391 1.3152216131335934 0.1884354334225007 1.0 0.6011355728196677 10 Q9UPT9 1 +Eukaryotic translation initiation factor 2 complex 0.7709114906726691 1.2859549850125966 0.1984587722702389 1.0 0.6187774471567055 3 Q9BY44 1 +Gemini of coiled bodies 0.6022094762526493 1.2773511357499736 0.2014783078490376 1.0 0.6187774471567055 5 Q8TEQ6,Q16637 2 +Cytosolic small ribosomal subunit 0.4470694297941971 1.2695662069530975 0.2042391931306149 1.0 0.6251375303254632 33 Q7Z478,Q9BY44,P62081,P60866,P05198,P62701,P62847,P08708,P62854,P62266,P46783,P39019,P62753,P62841,P15880 15 +Exocyst 0.5593441479676473 1.2266614505319744 0.2199498623492646 1.0 0.6605555569120966 6 Q96KP1 1 +Septin cytoskeleton 0.5588762701733442 1.2244224959854697 0.2207928872566396 1.0 0.6605555569120966 6 Q9P0V9,Q16181,Q14141,Q9UHD8,Q15019 5 +Microtubule plus end 0.4923583850666002 1.214546056500032 0.2245392736542171 1.0 0.6645935655314603 9 Q14008,Q7Z460,Q15555,Q14203,Q15691,Q99661 6 +Protein kinase complex 0.4332363703152638 1.1978146639941156 0.2309891771432408 1.0 0.670757033627488 34 Q96T76,Q93100,Q00535,P49736,Q9NYV4,Q92759,P11802,O95067,O75909,Q00534,P18074,P20248,Q9Y376,P13010,P14635,Q8TEW0,O15111 17 +Chromatoid body 0.7396237682890372 1.165066375611583 0.2439921261497137 1.0 0.6845441430240338 3 Q08J23,Q8NHU6 2 +Anaphase promoting complex 0.4614714559151636 1.1638872066846364 0.2444697248016742 1.0 0.6845441430240338 10 O60566,Q9UJX5,Q9UJX4,Q16763,Q14999 5 +Eukaryotic translation initiation factor 4f complex 0.5030675287302848 1.157501446561065 0.2470675486368594 1.0 0.6845441430240338 8 P06730,Q15056,O43432,O60573,Q04637 5 +Microtubule end 0.4602634342513235 1.1512253730954698 0.2496395293119437 1.0 0.6845441430240338 11 Q14008,Q7Z460,Q15555,Q14203,Q15691,Q99661 6 +Cytosolic region 0.500259865832343 1.1429708147069175 0.2530507087413114 1.0 0.6852864714464236 8 Q9UQB8 1 +Golgi transport complex 0.6045400238948494 1.1411784909687883 0.2537956532021717 1.0 0.6852864714464236 4 P60953,Q14746,Q96JB2 3 +Wash complex 0.732358717546101 1.1370947356840384 0.2554986843990443 1.0 0.6852864714464236 3 Q2M389 1 +Protein phosphatase 4 complex 0.5946833930704754 1.0976834831457365 0.2723427245152217 1.0 0.7069985914349307 4 Q8TF05,Q9NY27,P60510 3 +Dynactin complex 0.5589782898510909 1.0787126697260978 0.2807158358873645 1.0 0.7204774711443406 5 O75935,Q9NZ32,P61163 3 +Phosphatidylinositol 3 kinase complex 0.7151388474171226 1.0710234344754737 0.2841588927396328 1.0 0.7244764127421283 3 Q99570,Q08AM6 2 +Ribose phosphate diphosphokinase complex 0.7148402508211387 1.069881056563748 0.2846728509229554 1.0 0.7244764127421283 3 P11908,O60256 2 +Zona pellucida receptor complex 0.5504974041173782 1.0399830489670097 0.2983477760797624 1.0 0.7487620086655532 5 P49368,P17987,P50991 3 +Centriolar satellite 0.4279246279926574 1.0168346483953143 0.3092320963030339 1.0 0.7630293402795831 27 P41440,Q9UPT5,O60271,P53350,Q12873,Q9BZI7,Q3SYG4,P11413,Q6UVJ0,P33176,Q13045,Q7Z4H7,Q9UIS9,Q03518,Q9Y5K6,Q15398,Q8NI35,Q00013,O43809 19 +Mediator complex 0.4374302041708814 1.016367903060492 0.3094542242065878 1.0 0.7630293402795831 12 Q00534,Q9Y2X0,P11802 3 +Tubular endosome 0.5755675029868454 1.0137334833595637 0.3107099423460682 1.0 0.7630293402795831 4 Q9Y5X3,O75436,Q96QK1 3 +Mmxd complex 0.575538629998632 1.0136071847271733 0.3107702279946647 1.0 0.7630293402795831 4 Q96T76,P18074 2 +Ubiquitin conjugating enzyme complex 0.570019904984968 0.989499429001393 0.3224188490903046 1.0 0.783140689747496 4 Q5VTR2 1 +Sperm head 0.6923007211692409 0.9840590965510658 0.3250864569268081 1.0 0.7875089036783106 3 P04075 1 +Dendrite terminus 0.686174977605253 0.9608971179400124 0.3366039000600005 1.0 0.7962483902202623 3 P07900,P08238 2 +Dendritic growth cone 0.686174977605253 0.9608971179400124 0.3366039000600005 1.0 0.7962483902202623 3 P07900,P08238 2 +P body 0.3954125577239709 0.9520913045319422 0.3410506785634366 1.0 0.7989196906696965 35 P60900,Q9Y2V2,P25789,Q92900,P25787,Q96F86,P26196,P19474,Q86TB9,Q6P2E9,Q5PRF9,Q9UIV1,O75534,Q9HCE1,Q96C86,P06730,O60573,Q13501,A5YKK6 19 +Chaperone complex 0.4213628844135657 0.9509695042253588 0.3416198568268558 1.0 0.7989196906696965 25 P49368,Q99832,O95456,P50991,P78371,Q15185,Q16543,P40227,P08238,P11142,Q969U7,Q9UBS4,P17987,Q8WXX5,P48643 15 +Er membrane insertion complex 0.6781128695132876 0.93053932864667 0.3520919111333469 1.0 0.8075036449135337 3 P46379,Q7L5D6 2 +Cytoplasmic dynein complex 0.4210684107236886 0.9301889492607928 0.3522732625102494 1.0 0.8075036449135337 11 Q9UJW0,Q14204,Q96EX3,P63172,O43237,Q9Y6G9 6 +Main axon 0.4208340657290594 0.9288851435514748 0.3529486130085644 1.0 0.8075036449135337 11 Q8IXJ6,Q8TEW0,P04350,P78559 4 +Ruffle membrane 0.4138374677544548 0.9261582249053824 0.3543637589114818 1.0 0.8086991576166311 27 P50570,Q13153,P19174,O60610,P15531,P31751,Q9Y490,Q16512,Q92974 9 +Aggresome 0.4342463640555082 0.902979003067707 0.3665370388106002 1.0 0.8294939659656367 9 P28340,Q13501 2 +Phosphatase complex 0.4183551942309564 0.8946882876682763 0.3709537414047656 1.0 0.836030073912233 17 Q8TF05,P63151,Q15257,P30154,Q14738,Q08209 6 +Lewy body 0.6646760226933313 0.8803017448597314 0.3786958676343257 1.0 0.847156681670862 3 Q9Y3I1,Q13501 2 +Schaffer collateral ca1 synapse 0.4090435804007216 0.8478721200777883 0.3965091927906861 1.0 0.8719352637581592 14 P35080,Q08209,Q9UQB8 3 +Core mediator complex 0.4599388278653724 0.8430144064395075 0.3992203866968076 1.0 0.873656208568376 7 Q9NPJ6,Q9Y2X0,Q15648 3 +Cul4a ring e3 ubiquitin ligase complex 0.6505484476939016 0.8280418635583963 0.4076467918357049 1.0 0.8846832560556859 3 Q92990 1 +Kinetochore microtubule 0.4747626815903353 0.8271269287498749 0.408165122551078 1.0 0.8846832560556859 6 Q7Z460,P50748 2 +Dynein complex 0.4021990874295541 0.8143236088736754 0.4154595882491914 1.0 0.8940769286312765 13 Q14204,Q14203,P63172,O43237,Q9Y6G9 5 +Centriole 0.3954511426754427 0.800012521293929 0.4237035425769666 1.0 0.9053665320158768 26 Q13464,Q15154,P53350,O14965,Q9Y5Y2,Q8IXJ6,Q6UVJ0,P62826,P0DMV9,Q14203,Q9P287,Q96CW5,Q96EX3,P42858,Q5SW79,Q9UIS9,Q9BPX3,P27695 18 +Nuclear cyclin dependent protein kinase holoenzyme complex 0.4905627927414178 0.7718131246787429 0.4402251171595011 1.0 0.9222009931537992 5 Q9NYV4,O75909 2 +Proton transporting v type atpase complex 0.391465832450748 0.7681939201964436 0.4423719849929814 1.0 0.9222009931537992 11 Q9Y5K8 1 +Rna polymerase ii transcription regulator complex 0.3657921144058671 0.7679956291099488 0.4424897816556321 1.0 0.9222009931537992 36 P29083,Q96T76,Q92759,Q8TEQ6,Q9Y2X0,P35269,P18074,Q15648,P40763,Q04727 10 +Cytoplasmic stress granule 0.3326491795606901 0.7677265886031338 0.4426496363521877 1.0 0.9222009931537992 44 P05198,P67809,Q6Y7W6,Q13464,Q6PKG0,P26196,P06730,Q92499,Q13283,Q13310,Q14258,O75534,Q14157,Q04637,Q9HCE1,Q06787 16 +Vacuolar proton transporting v type atpase v0 domain 0.6334761665812911 0.765797999998499 0.4437965044316296 1.0 0.9222009931537992 3 Q9Y487 1 +Proton transporting v type atpase v0 domain 0.6334761665812911 0.765797999998499 0.4437965044316296 1.0 0.9222009931537992 3 Q9Y487 1 +Endoribonuclease complex 0.3946307298843247 0.7601955196974474 0.4471377226740207 1.0 0.9270177957498004 17 O15091,O75569 2 +Ciliary plasm 0.3887088587181603 0.7266473204705762 0.4674420321618213 1.0 0.9503636867644224 19 O95352,Q9Y6D5,P04350,Q15555 4 +Translation preinitiation complex 0.3876535408215413 0.7235770158928445 0.4693254561686237 1.0 0.9503636867644224 16 Q7Z478,Q9Y262,O75821,P41567,Q14152 5 +Phosphatidylinositol 3 kinase complex class iii 0.8426865671641826 0.7225815436111953 0.4699370106737983 1.0 0.9503636867644224 2 Q08AM6 1 +Cia complex 0.8367164179104477 0.7038161959955764 0.4815472461911305 1.0 0.9649235135375918 2 Q96T76 1 +Photoreceptor connecting cilium 0.6127202149895605 0.6917331472159454 0.4891049266299183 1.0 0.970648543165544 3 Q15019,Q15555 2 +Equatorial microtubule organizing center 0.8325373134328388 0.6907680710753387 0.4897113036422458 1.0 0.970648543165544 2 Q9BSJ2 1 +Filopodium 0.362144452915407 0.6836470790661944 0.4941980484403376 1.0 0.9712438869564988 33 Q00535,Q9UQB8,P60953,Q6IBS0,P26038,Q06787,O95782,Q7L576,Q9H4L5,P78310,P51114,Q96EX3,P35241,Q9UM54,P51116,O15357,P61086,Q16658,Q7Z7E8,Q14204,P15311 21 +Sperm principal piece 0.8283582089552239 0.6777946060058603 0.4979019315782986 1.0 0.9737593390366168 2 P08237 1 +Platelet alpha granule 0.3771064323734748 0.6741329876447598 0.500226768839735 1.0 0.9737593390366168 14 Q8NBX0 1 +Sperm annulus 0.6070468796655693 0.6718425324930806 0.5016839484871967 1.0 0.9737593390366168 3 Q14141,Q15019 2 +Cul5 ring ubiquitin ligase complex 0.606748283069566 0.6708002267434171 0.5023478030079203 1.0 0.9737593390366168 3 Q93034,Q15369 2 +Rna cap binding complex 0.4398462571794845 0.6697745605718483 0.5030015128798417 1.0 0.9737593390366168 6 P06730,Q06787,O60573,Q7L576 4 +Gamma tubulin complex 0.5997688903576902 0.6465726901357285 0.5179085377676382 1.0 0.9918764064448524 3 Q9BSJ2 1 +Ciliary tip 0.3965192071625744 0.6256603750429817 0.5315377289325554 1.0 1.0 8 Q15555 1 +Copi coated vesicle membrane 0.3631033043484609 0.6201677282163939 0.5351473658028016 1.0 1.0 11 P53618,P48444,P53621,P61923,Q9UBF2,P35606,P24390 7 +Ribonucleoprotein granule 0.3034525068278812 0.6178872783498273 0.5366496454544465 1.0 1.0 114 P60900,Q9Y2V2,P25789,Q16637,Q8NHU6,Q92900,Q5TAX3,Q13310,Q14258,O75116,P25787,Q06787,Q96F86,Q9H6S0,P26196,P62701,P42694,P51114,Q92499,Q14157,P19474,Q86TB9,Q9HAU5,P51116,Q9NUL7,Q6Y7W6,Q6P2E9,Q6PKG0,Q08J23,Q5PRF9,P07437,Q9UIV1,Q13283,O75534,Q04637,P62753,Q9HCE1,Q7L8L6,P05198,Q96C86,P06730,O60573,Q13501,P67809,A5YKK6 45 +Distal axon 0.2459730167612845 0.616161843851789 0.5377877085947338 1.0 1.0 56 P53621,Q00535,Q6IBS0,P46940,Q9UBF2,P27708,Q96Q89,Q06787,P22681,Q96N67,P38935,P51114,P08238,O14617,P51116,Q8IXJ6,Q14141,P50570,O75150,P43034,P07900,Q8TAG9,Q93008,P27695 24 +Cyclin cdk positive transcription elongation factor complex 0.4807920602329208 0.6154497710779309 0.5382577309954422 1.0 1.0 4 O75909 1 +Centriolar subdistal appendage 0.5897282770976315 0.6121977369776506 0.540406938667938 1.0 1.0 3 Q14203,Q5SW79 2 +Manchette 0.5828638442241907 0.5890447975111422 0.5558312228612665 1.0 1.0 3 Q96SI9 1 +Copii vesicle coat 0.3564312110676373 0.5867447042869955 0.5573751789918917 1.0 1.0 11 Q9NR31,O95487,P53992,Q9Y6B6,Q15436,O94979 6 +Glial cell projection 0.440315306134563 0.5611623564256049 0.5746868623282793 1.0 1.0 5 P05198,Q06787 2 +Elongin complex 0.5736040609137155 0.5582935939960852 0.5766439185887191 1.0 1.0 3 Q15370,Q15369 2 +Nuclear ubiquitin ligase complex 0.353529118999359 0.5488045735095497 0.5831395713235643 1.0 1.0 15 Q9NXR7,O60566,Q9UJX5,Q6W2J9,Q9UJX4,Q14999,Q16763 7 +Arp2 3 protein complex 0.4082486551105724 0.5351881027614291 0.5925197922956484 1.0 1.0 6 O15144,P61160,P59998,O15145,Q92747 5 +Multimeric ribonuclease p complex 0.4593247975974601 0.5327325461559208 0.5942187332900284 1.0 1.0 4 O75818 1 +Site of polarized growth 0.2815817998881698 0.521160666263124 0.6022548523459403 1.0 1.0 48 P53621,Q00535,Q96N67,P38935,P50570,Q8IXJ6,P43034,P07900,P27695,Q8TAG9,P51114,Q6IBS0,Q93008,Q9UBF2,Q96Q89,Q06787,P51116,P22681 18 +Neuron projection terminus 0.3465641944644138 0.5146829020488243 0.6067746232285716 1.0 1.0 15 O75150,Q9UQB8,Q14141,Q15334,P27708,O14617,Q06787 7 +Trans golgi network 0.232506640697971 0.501316775855262 0.6161482006320891 1.0 1.0 61 Q4J6C6,Q92538,Q9NR09,Q9UID3,Q5VYK3,Q96JB2,P20645,Q92614,Q9UJY4,Q9Y6D5,P57737 11 +Haus complex 0.4237369449186212 0.4963193193850266 0.6196691378892356 1.0 1.0 5 Q7Z4H7 1 +Actin based cell projection 0.2727888657105398 0.4921019046911677 0.6226473058442283 1.0 1.0 49 Q9Y696,Q00535,P36543,Q9UQB8,O15357,P43034,P60953,Q14204,P51114,P61086,Q6IBS0,Q00013,P35241,Q06787,P15311,Q7L576,P51116,Q7Z7E8 18 +Contractile ring 0.4220788157798733 0.4899930136381618 0.6241388425657293 1.0 1.0 5 Q9NQW6,P35579,Q96Q89 3 +Prefoldin complex 0.5494925245772782 0.4810974863985728 0.6304472144750402 1.0 1.0 3 Q99471 1 +Early endosome membrane 0.291347448971337 0.462763846780137 0.6435336480331535 1.0 1.0 44 Q96PE3,Q96T51,Q9H4M9,Q7Z3T8,Q7Z3U7,Q08AM6,O60493,Q9BZF3,Q9UJY4 9 +Multivesicular body 0.3581830501698201 0.456464553560013 0.6480559546474147 1.0 1.0 8 Q5VYK3 1 +Small ribosomal subunit 0.281877874854517 0.4557596153466724 0.6485628475138645 1.0 1.0 46 Q7Z478,Q9BY44,P62081,P60866,P05198,P62701,P62847,P08708,P62854,P62266,P46783,P39019,P62753,P62841,P15880 15 +Retromer complex 0.3413608279780183 0.4503835598512709 0.6524338971130739 1.0 1.0 9 O75436,O60749,Q96QK1,Q9UBQ0,Q9UNH7,Q9Y5X3,O60493 7 +Paranodal junction 0.7492537313432892 0.4493784867297111 0.6531586478045153 1.0 1.0 2 O15020 1 +Polar microtubule 0.7486567164179128 0.4478006170520006 0.6542970980496807 1.0 1.0 2 Q96CW5 1 +Flotillin complex 0.3710195803627579 0.4468169315925716 0.6550072452239171 1.0 1.0 7 P22681 1 +Cilium 0.2562932498658039 0.4422250543383919 0.6583263576780842 1.0 1.0 88 P47756,Q9Y5K8,Q8TD19,Q15555,Q99570,Q9Y6D5,Q3SYG4,P22681,P08237,P14618,P57076,P33176,P28070,Q9BW83,Q92973,Q13526,Q9Y5Y2,O14965,Q13618,Q14141,P04350,Q14203,Q00796,Q9UIS9,O95352,Q9H4M9,P43034,P36404,P00568,Q13501,Q01968,Q5SW79,Q15691,P15311 34 +Intercellular bridge 0.3330240925347209 0.4372921953545799 0.6618994547292014 1.0 1.0 21 Q6IBW4,Q13432,O75937,Q96Q89,Q96TC7,Q7Z5K2 6 +Spindle microtubule 0.3222515255824883 0.4353771964591476 0.6632886596527665 1.0 1.0 32 Q15691,P43034,P53350,Q7Z460,Q7Z4H7,O14965,Q13618,Q8IX90,Q9BT25,Q96CW5,Q00610,O43264,Q96TC7,P50748,O95239,P52732 16 +Dendritic tree 0.2808845111076276 0.4288489402675984 0.6680331604153813 1.0 1.0 113 Q00535,Q9UQB8,P17655,Q7Z460,P78559,Q06787,Q16512,Q9Y6D5,Q9BPU6,Q99996,Q08209,P40818,P21359,Q66K74,Q9P265,P62753,Q9Y5K6,P42858,Q9UBB6,P12277,Q13614,P27695 22 +Hulc complex 0.74029850746269 0.4259773076372375 0.6701243814156568 1.0 1.0 2 Q5VTR2 1 +Rna polymerase complex 0.2918236727676264 0.417401374820175 0.676384849449166 1.0 1.0 42 P29083,Q96T76,Q9BUI4,O14802,P25205,Q92759,P35269,P18074,P49642 9 +Extrinsic component of organelle membrane 0.3211022326853124 0.4028417206894047 0.6870646669574012 1.0 1.0 14 Q08AM6,P40818 2 +Ribonuclease mrp complex 0.3981367280375485 0.4023035226134486 0.6874606624950852 1.0 1.0 5 O75818 1 +Transcription elongation factor complex 0.3242460989932658 0.3994070609746818 0.6895932920240204 1.0 1.0 24 Q6IA86,O00267,Q15370,Q15369,Q9NYV4,Q8IXH7,P18615,Q6PD62,O75909,Q7KZ85,Q08945,Q9Y5B9,Q9GZS3 13 +Perikaryon 0.3246372268459344 0.3986110267367613 0.6901798354535518 1.0 1.0 21 Q6Y7W6,Q00535,Q8IXJ6,Q16637,Q9UBB6,Q9P265,Q06787 7 +Calcium channel complex 0.3430093714071048 0.3954091415036072 0.6925409636538058 1.0 1.0 8 Q15257 1 +Potassium channel complex 0.7256716417910509 0.3890290123586317 0.697254684804592 1.0 1.0 2 Q99996 1 +Aryl hydrocarbon receptor complex 0.7176119402985127 0.369376201960747 0.7118473338331284 1.0 1.0 2 O00170 1 +Neuron spine 0.3072047501286499 0.367990906347324 0.7128800148534911 1.0 1.0 33 Q9UQB8,Q9Y6D5,Q06787,Q08209,P40818 5 +Transcription preinitiation complex 0.412192477422942 0.3676221917680237 0.7131549652377736 1.0 1.0 4 P29083 1 +Axon cytoplasm 0.3136958037868376 0.3509362692206271 0.7256361608920059 1.0 1.0 23 Q9NZ32,P43034,Q03001,Q9Y2T2,P27695,O00203,P33176,Q14204,P78559,O14617,O60333 11 +Cytoplasmic region 0.2185090963811355 0.3481174495777113 0.7277519801107994 1.0 1.0 64 Q9NZ32,Q9UQB8,P43034,Q9Y2T2,Q7Z460,P27695,Q15555,P04350,Q99570,P78559,Q06787,Q9Y6D5,O95352,O60333 14 +Neuron projection cytoplasm 0.3007583386169649 0.3459429516988727 0.7293855884473139 1.0 1.0 34 Q9NZ32,Q9UQB8,P43034,Q9Y2T2,P27695,O00203,Q15334,P33176,Q14204,P78559,Q06787,O60333 12 +Caveola 0.3025617180916775 0.3221837579163957 0.7473134883160903 1.0 1.0 15 Q8WTV0,P41440,P22681 3 +Cytoplasmic side of endoplasmic reticulum membrane 0.3351969422841022 0.3149179131665428 0.7528239803657208 1.0 1.0 7 P62854 1 +Crd mediated mrna stability complex 0.3473114880566136 0.3091066880350276 0.7572403718396041 1.0 1.0 6 P67809 1 +Extrinsic component of postsynaptic membrane 0.3694320350075578 0.3075708473084933 0.7584089059851695 1.0 1.0 5 Q99996 1 +Filtration diaphragm 0.6895522388059772 0.3051326959534906 0.7602650901008026 1.0 1.0 2 Q08209 1 +Nata complex 0.6883582089552276 0.3025490361237065 0.7622335583294495 1.0 1.0 2 Q9BXJ9 1 +Copi coated vesicle 0.2927505827586777 0.3014573528866749 0.763065765718735 1.0 1.0 12 P53618,P48444,P53621,P61923,Q9UBF2,P35606,P24390 7 +Ripoptosome 0.686865671641798 0.2993372300938526 0.7646827505807015 1.0 1.0 2 Q14790 1 +Extrinsic component of synaptic membrane 0.3440577630627061 0.2986552597287903 0.7652030973515762 1.0 1.0 6 Q99996 1 +Germ cell nucleus 0.316177536092052 0.2978485832241823 0.7658187323448507 1.0 1.0 8 Q92547,Q15645 2 +Protein lipid complex 0.3882472820630084 0.2947191941005173 0.7682083993339632 1.0 1.0 4 Q9UHG3,Q00341 2 +Eukaryotic translation initiation factor 3 complex 0.2928961795508478 0.2909417737455082 0.7710958517272437 1.0 1.0 14 P60228,Q92905,P55884,Q13347,Q9Y262,O15371,O75821,Q14152 8 +Site of double strand break 0.2934615843095428 0.290688035918049 0.771289922625856 1.0 1.0 31 Q9H4L7,O60921,P35244 3 +Cell body 0.2495248345312521 0.2762773894029568 0.7823350209668571 1.0 1.0 103 Q00535,Q9UQB8,P17655,Q7Z460,Q16637,P27708,P78559,Q06787,O15020,Q9BPU6,Q99996,P51114,P51116,P49368,Q6Y7W6,Q66K74,Q14790,Q8IXJ6,O14965,P04350,Q14203,Q13283,P07437,Q14155,Q9P265,P62753,Q9H269,P17987,Q9H814,P43034,Q9UBB6,P12277,P42574,P48643 34 +Early endosome 0.2401069808024047 0.2740840440275019 0.7840200355115676 1.0 1.0 94 P41440,Q7Z3U7,Q9BZF3,Q96PE3,P36507,P40818,Q96T51,P31751,Q08AM6,O60493,Q9H269,P28482,Q9H4M9,Q7Z3T8,Q5VYK3,P42858,Q9Y5X3,Q9UJY4,O95630,P27695 20 +Endoplasmic reticulum exit site 0.2890051781638192 0.261809448332845 0.7934683543670531 1.0 1.0 18 Q9NR31,O95486,Q92734,P53992,O95487,Q8WUM4,Q9Y6B6,O15027,Q15436,O94979 10 +Tertiary granule lumen 0.2855665635020349 0.2531753780957503 0.8001326922598595 1.0 1.0 17 O75874,P04075,P09972,Q99439,Q9NQR4,P09960,P04080,P36871,Q8IUR7 9 +Female pronucleus 0.3668308643967884 0.2370063785749845 0.8126518418387152 1.0 1.0 4 P11166,P20248 2 +Meiotic spindle 0.3655026819488222 0.2336761190903977 0.8152364287252267 1.0 1.0 4 O14965 1 +Neuromuscular junction 0.2737942054805785 0.2321569485317144 0.8164161143713433 1.0 1.0 13 P46109,P35579,Q00535,Q15334 4 +External side of plasma membrane 0.2793348735284581 0.2273446744625246 0.8201557372341923 1.0 1.0 19 P17655,P41440,P00813 3 +Beta catenin destruction complex 0.339707200478039 0.2236796465449361 0.8230065844007284 1.0 1.0 5 P49840,P48729,P49841,Q9HB71 4 +Mcrd mediated mrna stability complex 0.3372122825364709 0.2173611831304386 0.8279268793910615 1.0 1.0 5 O75534 1 +Cell projection membrane 0.1963145783711595 0.2164618093465051 0.8286277911793511 1.0 1.0 61 Q9H4M9,P15531,P31751,Q16512,Q3SYG4 5 +Intracellular protein containing complex 0.3591415305888747 0.2123738699987871 0.8318153695409343 1.0 1.0 256 Q8NCA5,Q15369,P62333,Q7Z392,P25205,Q9BXJ9,Q9GZZ1,Q9NW08,P25787,Q7L576,Q14999,O00487,Q13616,Q9H1A4,O60566,Q9HB71,P28066,Q92499,Q96S59,Q86VP6,Q13617,O43396,P28070,Q9UPT9,Q5TAQ9,Q9Y4B6,Q05086,O95376,Q96P70,Q5VZE5,Q96BN8,P30154,Q5VYK3,P35269,Q9Y3I1,P25786,P20618,P49005,Q8TF05,Q14997,P55036,P67870,Q08209,Q15386,P28340,Q15257,Q92759,Q9UJX4,Q9UIV1,Q16186,O95628,Q6W2J9,Q07864,O15160,P62195,P60510,Q16763,P62191,O00170,Q96K76,Q92990,Q93034,Q9NT62,P18074,Q96P16,Q06787,Q14CX7,Q9BUI4,Q13619,O14818,P68036,O43242,O43318,P61289,P61962,P49642,P49721,P19784,Q6IA86,Q13618,Q14185,Q9Y5K5,Q9NR50,O75150,P06730,O75792,Q5VTR2,P28074,O60573,A5YKK6,P29083,P63151,P49643,P43686,P60900,P25789,Q15008,Q92600,Q9UL63,Q13309,Q00653,Q9NXR7,O14802,Q9H9T3,P49720,P13984,P08238,O75832,Q8IWV7,Q13555,O95163,Q8IUR7,Q96T76,Q9NZL9,Q9Y4A5,Q9UJX5,Q9BW61,Q14738,P17612,P13010,Q13200 121 +Host cellular component 0.332835374962646 0.2065582481984432 0.8363548700940213 1.0 1.0 5 P63172,O60684,O00505,P52292 4 +Spindle pole centrosome 0.2967614065029932 0.2006354950623719 0.8409836013363392 1.0 1.0 7 Q9Y5Y2,O14965 2 +Dna repair complex 0.2704229960479298 0.2005578549590285 0.8410443152701297 1.0 1.0 19 P54277,P20585,P28340 3 +Axon 0.2612515731149706 0.1966798201095572 0.8440781028564275 1.0 1.0 131 P11310,P53621,Q00535,Q7Z460,Q16637,Q6IBS0,Q9UBF2,P27708,Q96Q89,P78559,Q16512,Q06787,P22681,O60333,Q96N67,P38935,P51114,P08238,P33176,O14617,Q8TEW0,P51116,P21359,P78344,Q9Y2T2,Q8IXJ6,O14965,P04350,Q15334,Q14203,Q9P265,Q9H269,P50570,Q9NZ32,P43034,Q13153,O75150,Q03001,P07900,Q9Y5K6,Q8TAG9,O00203,P42858,Q93008,Q9UBB6,Q14204,Q13614,P27695 48 +Polysomal ribosome 0.269344551314495 0.1923006605748825 0.8475067009914989 1.0 1.0 27 P62899,P20290,P62917,P62854 4 +Escrt complex 0.3259635494472621 0.1903294761531502 0.8490509571677185 1.0 1.0 5 Q8WUX9,Q92783,Q9H9H4,Q99816 4 +Vesicle lumen 0.2479545429602639 0.1901093168237372 0.8492234694515997 1.0 1.0 118 P00813,Q9NQR4,Q7Z6Z7,Q15008,Q16539,Q8NBX0,P22392,P20618,P25787,O00487,Q9Y376,O75874,P04075,P09972,Q9NTK5,P14618,O43242,P28066,P17858,P53396,P12268,P09429,P67870,Q86VP6,Q99439,P07437,P20839,P07741,P13639,P28482,Q8IUR7,Q9UNP9,Q9UNF1,O95352,P46976,P00491,Q9NZ32,P07900,P04080,P63172,P06737,O00764,Q14204,P18669,Q13200 45 +Cluster of actin based cell projections 0.258817471328523 0.1890128601522308 0.8500827375235407 1.0 1.0 36 P47756,O00299,P41440,P35579,P43034,O00429,Q9Y5X3,Q6IBS0,Q9UEY8,P08238,P15311,P47755,Q00013 13 +Cell tip 0.6244776119403042 0.1835778129246465 0.8543446700115627 1.0 1.0 2 P35241 1 +Contractile fiber 0.1911651575174775 0.1833529529657923 0.8545210880990843 1.0 1.0 56 P47756,O75880,P04075,P60900,Q14331,Q13153,Q16637,P51114,Q6IBS0,Q9Y376,Q13501,Q96AC1,Q16512,Q08209,Q5VU43 15 +Escrt i complex 0.6232835820895579 0.1817255388220909 0.8557981225986069 1.0 1.0 2 Q9H9H4 1 +Spindle pole 0.1931808879212987 0.1816796951456289 0.8558341016908242 1.0 1.0 64 P53350,Q16539,Q9BT25,Q92547,Q96Q89,P50748,Q14008,P13693,Q9NR09,Q96CW5,Q96TC7,O14965,Q9Y5Y2,Q13618,Q9BSJ2,Q14203,Q13432,Q14155,O75351,O43264,Q15398,P14635,P52732 23 +Centrosome 0.2907250750047189 0.1787760213217866 0.8581135741486787 1.0 1.0 171 Q9Y696,P41440,Q5T4S7,Q9NQR4,P53350,Q7Z460,P25205,Q9Y5K8,O95067,Q9BT25,Q00013,Q96Q89,P25786,O75116,Q3SYG4,Q14999,Q5VU43,P11413,P62081,Q14008,Q99996,Q9NTK5,Q99504,Q96CW5,P33176,Q9BTW9,Q99661,Q9BW83,Q7Z4H7,Q9Y5Y2,Q8IXJ6,Q13618,O14965,Q9BSJ2,Q14203,Q13432,Q14155,O43237,P17987,Q16513,Q9UIS9,Q9UNN8,Q7Z5K2,Q9H814,Q15691,P50570,P43034,P36404,P43487,O75935,Q9Y5K6,Q5VYK3,Q00534,O75351,Q8TD16,P28074,Q14204,Q5SW79,Q15398,P14635,Q8NI35,P48643,P27695 63 +Polymeric cytoskeletal fiber 0.3023825952809412 0.1761827374101662 0.8601503822026542 1.0 1.0 187 P68371,Q00535,Q9UQB8,Q6NUK4,Q7Z460,Q9H6U6,Q9H6H4,Q9H0B6,Q96IZ0,Q15555,Q6IBS0,Q9BT25,Q9BUF5,Q15813,O94967,Q96Q89,P78559,P50748,Q16512,Q9Y6D5,Q9NZQ3,Q14152,O60333,O00401,Q14008,P13693,O15344,P36507,O00429,Q96CW5,P33176,P16949,Q9BTW9,Q96TC7,P29372,Q92974,Q99661,P49368,Q66K74,Q9P258,Q99426,Q7Z4H7,Q8IXJ6,Q13618,O14965,Q86TI2,Q9BSJ2,Q14203,P04350,P07437,O43237,P17987,Q9HC35,P50570,Q13153,P43034,Q03001,Q9Y5K6,P00568,Q15058,P63172,O43264,Q13885,Q14204,Q5SW79,Q15691,P15311,P52732,P48643 69 +Microvillus membrane 0.3396057347670111 0.174830614567872 0.8612127318570353 1.0 1.0 4 O14745,P15311,P26038 3 +Membrane coat 0.2430256671750802 0.1712119742995731 0.8640570923874915 1.0 1.0 41 P53621,P53992,Q8NC96,Q9UBF2,Q9NVZ3,Q9Y6B6,Q15436,P61923,O14617,O95486,Q9Y2T2,O95487,P53618,Q9NR31,P48444,Q9Y678,O00203,Q00610,P35606,O94979,Q14677 21 +Somatodendritic compartment 0.2671934570737778 0.1673650294703998 0.8670828394759296 1.0 1.0 146 Q00535,Q9UQB8,P17655,Q7Z460,P78559,Q16512,Q06787,Q9Y6D5,O15020,Q9BPU6,Q99996,Q08209,P40818,P21359,Q66K74,O14965,P04350,Q14155,Q9P265,P62753,Q9H269,Q9H814,Q9Y5K6,P42858,Q9UBB6,P12277,P42574,Q13614,P27695 29 +Cell trailing edge 0.2953969246572591 0.1667327961751986 0.8675802991148633 1.0 1.0 6 P41440,P35579 2 +Protein acetyltransferase complex 0.258480499140854 0.162074102057537 0.8712475001011675 1.0 1.0 27 Q9UPT9,Q5VZE5,Q14CX7 3 +Mitotic spindle midzone 0.2920074900185101 0.1593543669490695 0.873389689315534 1.0 1.0 6 Q96Q89 1 +Cell division site 0.2570257034260249 0.1583584027812473 0.8741743898909413 1.0 1.0 27 Q9P0V9,O75935,Q9H8V3,Q9BSJ2,Q96CW5,P35241,O95630,Q16512,Q16513 9 +Costamere 0.2887029288702885 0.1523954328230262 0.8788750590854253 1.0 1.0 6 Q09666,Q15149,Q12955,P51114,P18206 5 +Outer kinetochore 0.2622853973787535 0.1504858175022723 0.8803813393134443 1.0 1.0 8 Q8IX90,P53350,P14635,O60566 4 +Transcription regulator complex 0.2073380127403798 0.1500101230561187 0.8807566285927699 1.0 1.0 85 P53999,P29083,P51858,Q96T76,P27695,Q99504,Q92759,Q8TEQ6,P11802,P35269,Q9Y2X0,P18074,Q9BXJ9,P09429,Q6P1K2,Q15648,P40763,Q04727 18 +Golgi apparatus subcompartment 0.2079955684583436 0.148763985211288 0.8817398699892933 1.0 1.0 86 Q4J6C6,Q99996,Q92538,Q9NR09,Q9UID3,Q9Y6B6,Q99986,Q5VYK3,Q96JB2,P20645,Q9UJY4,Q92614,Q9Y6D5,P57737 14 +Microtubule organizing center 0.3121974171195441 0.1473987013302532 0.882817330515536 1.0 1.0 214 Q7Z460,P25205,Q9BT25,O75116,Q9Y6D5,Q3SYG4,Q14999,O60566,Q96CW5,P28070,Q99661,Q9BW83,Q14155,P17987,Q9H814,P50570,P43034,P36404,Q5VYK3,Q8TD16,Q14204,Q5SW79,Q15398,Q9BPX3,Q9Y696,Q9NQR4,Q9Y5K8,O95067,Q96Q89,P25786,Q16512,Q99996,Q9NTK5,Q99504,Q9BTW9,Q7Z4H7,Q9BSJ2,Q13432,O43237,Q16513,Q9UIS9,Q9HC35,P43487,O75935,O60610,P42858,Q00534,Q15691,P60510,Q8NI35,P48643,P41440,Q5T4S7,Q96CT7,Q5VU43,Q14166,Q14008,Q9NR09,P33176,Q9Y5Y2,Q8IXJ6,Q13618,Q14203,Q9UNN8,Q7Z5K2,Q13153,O75351,P28074,P15311,P14635,Q00013,P27695,P53350,Q8TD19,Q15555,Q92547,Q9Y6G9,P11413,P62081,Q9Y3P9,Q13526,Q13464,Q13045,O14965,P28482,Q96T76,Q9Y5K6 87 +Mitotic spindle microtubule 0.2732939275983408 0.1468506553083554 0.8832499009055528 1.0 1.0 7 Q7Z4H7,Q9BT25,Q00610 3 +Site of dna damage 0.2291802739129418 0.1433208562645042 0.8860367849509552 1.0 1.0 43 Q9H4L7,O60921,Q9BUR4,P35244 4 +Trans golgi network membrane 0.2493064638415476 0.1412313653641353 0.8876871684279874 1.0 1.0 23 Q9UID3,P20645 2 +Signal recognition particle 0.2809324566646648 0.1369454188147879 0.8910739379793238 1.0 1.0 6 Q9UHB9,P37108,P61011,O76094,P09132 5 +Autophagosome 0.2467934419822273 0.1345543922010521 0.8929642033260776 1.0 1.0 25 P42858,Q13501,P19474,Q9H269,P27695 5 +Plasma membrane raft 0.2434007933402612 0.1331054832901846 0.8941099586983299 1.0 1.0 20 Q8WTV0,P41440,P22681 3 +Vesicle coat 0.2427727476214983 0.1306580811341975 0.8960457943941298 1.0 1.0 32 P53618,Q9NR31,P53621,O95486,P53992,P48444,Q9Y678,Q9Y6B6,Q15436,P61923,O94979,Q00610,Q8NC96,Q9UBF2,Q9NVZ3,P35606,O95487,Q14677 18 +Brush border 0.2418992667070937 0.1271394667512927 0.8988300149555908 1.0 1.0 31 P47756,O00299,P41440,P35579,O00429,Q9Y5X3,Q9UEY8,P08238,P15311,P47755 10 +Cortical actin cytoskeleton 0.236560903964803 0.1236120404726477 0.901622458689484 1.0 1.0 35 O15020,P17655 2 +Cul4b ring e3 ubiquitin ligase complex 0.5797014925373203 0.1235112320233127 0.9017022805240268 1.0 1.0 2 Q13620 1 +Pml body 0.2399991993765574 0.1212358915365556 0.9035041964394168 1.0 1.0 29 Q96EB6,Q9UER7,Q13501,Q86TB9,Q13535 5 +Inclusion body 0.2397113636657606 0.1206670798685043 0.9039547348767284 1.0 1.0 29 P28340,Q9Y3I1,Q9UL15,P42858,Q13501,P13639,P13807,P27695 8 +Cortical cytoskeleton 0.2177898531541335 0.1190376475495044 0.905245529385915 1.0 1.0 44 P47756,O15020,P41440,O00401,P35579,P17655,Q7Z460,Q15334,P35241,Q15691,P15311,P47755,P60981 13 +Spindle midzone 0.2330207144080363 0.1159595332121991 0.907684613193268 1.0 1.0 19 Q99741,Q9P258,P53350,O14965,Q15555,Q15058,Q13432,Q96Q89,Q15691 9 +Supramolecular complex 0.2643888981402281 0.1114275463402231 0.9112773172515808 1.0 1.0 386 Q00535,Q14331,Q9UQB8,Q7Z460,Q96IZ0,Q9BT25,Q9BUF5,Q6P1K2,O75116,P25787,Q96DY7,P50748,Q9Y6D5,O60333,O60566,P13693,P26196,Q92499,Q96CW5,Q14157,Q8IWS0,Q99661,Q9H900,Q9P258,Q08J23,Q86TI2,O75534,P17987,P50570,P43034,Q14204,P67809,Q5SW79,O75880,Q9Y2V2,Q9HBM1,Q9H6U6,Q9H6H4,Q9H0B6,Q8NHU6,Q5TAX3,Q13310,Q6IBS0,Q96Q89,Q16512,O00401,P04075,P62701,P51114,Q9BTW9,Q96TC7,Q96BK5,Q86TB9,Q92974,Q08209,Q2NKX8,Q6Y7W6,Q6P2E9,Q7Z4H7,Q9BSJ2,Q9UIV1,O43237,Q9HCE1,P05198,Q9HC35,O75935,Q13885,P63172,Q15691,P52732,P48643,P47756,Q6NUK4,Q16637,Q15813,Q14258,O94967,P78559,Q06787,Q96F86,Q9NZQ3,Q5VU43,Q9Y376,Q14008,O14980,O15344,O43684,O00429,P33176,P16949,P19474,P29372,P51116,P49368,P35579,Q99426,Q8IXJ6,Q13618,Q5PRF9,Q14203,Q13283,Q04637,Q7L8L6,Q13153,Q96C86,Q03001,P06730,P00568,O60573,Q13501,O43264,A5YKK6,P14635,P15311,P68371,P60900,P33981,P53350,P25789,Q15555,Q92900,Q9H6S0,Q14152,P36507,P42694,Q96AC1,Q9HAU5,Q9NUL7,Q66K74,Q6PKG0,O14965,P04350,P07437,P62753,Q9Y5K6,Q15058 136 +Rna polymerase ii holoenzyme 0.2341718421600463 0.1099667933721674 0.9124357102079528 1.0 1.0 27 P29083,P18074,Q92759,P35269 4 +Microtubule cytoskeleton 0.2775759194254261 0.1084636870785323 0.9136278840507026 1.0 1.0 373 Q00535,Q9UQB8,Q7Z460,P25205,Q99570,Q9BT25,Q9BUF5,O75116,P50748,Q9Y6D5,Q3SYG4,Q14999,O60333,O76071,O60566,P13693,Q96S59,Q96CW5,P28070,Q99661,Q9BW83,Q9P258,Q08J23,Q86TI2,Q14155,Q96P70,P17987,Q9H814,P50570,P43034,P36404,Q5VYK3,Q8TD16,Q14204,Q5SW79,Q15398,Q9BPX3,Q9Y696,Q9P0V9,Q9NQR4,Q9Y5K8,Q9H6U6,Q9H6H4,Q9H0B6,O95067,Q96Q89,P25786,Q16512,Q99996,Q9NTK5,Q99504,Q9BTW9,Q96TC7,Q96BK5,Q92974,Q7Z4H7,Q9BVQ7,Q9BSJ2,Q9UJX4,Q13432,O43237,Q16513,Q9UIS9,Q9HC35,P43487,O75935,O60610,P42858,Q00534,Q13885,P63172,Q15691,Q8NI35,P60510,P52732,P48643,P41440,Q5T4S7,Q6NUK4,Q16539,Q15813,P18074,Q96CT7,O94967,P78559,Q5VU43,Q14166,Q14008,Q9NR09,O15344,O00429,P33176,P16949,P29372,P31689,P49368,P35579,Q99426,Q9Y5Y2,Q8IXJ6,Q13618,Q14203,Q9UNN8,Q7Z5K2,Q9NZ32,Q13153,Q99986,Q03001,Q9H8V3,O75351,P28074,O43264,P14635,P15311,Q00013,P27695,P68371,P33981,P53350,Q15555,Q92547,Q9Y237,Q14152,P11413,P62081,P36507,Q66K74,O14965,P04350,P07437,P28482,Q96T76,Q9Y5K6,Q15058 134 +Aster 0.3770633657313709 0.1065953198842303 0.9151100316222248 1.0 1.0 3 P43034 1 +A band 0.2808680072990163 0.1064016687320165 0.9152636691384408 1.0 1.0 5 P04075 1 +Condensed chromosome centromeric region 0.188592688021511 0.1024001002387239 0.9184391041125486 1.0 1.0 80 P33981,P53350,Q7Z460,Q9HBM1,P42695,Q6P1K2,P50748,Q96DY7,Q9Y6G9,Q14008,O60566,O14980,O43684,Q8IWS0,Q96BK5,Q2NKX8,Q99661,O43683,Q9H900,Q14141,Q14203,Q8IX90,O43237,P43034,O75935,Q15021,O43264,P14635,Q9BPX3 29 +Mitotic spindle 0.1768048106395403 0.1006668117879995 0.9198149578589274 1.0 1.0 68 P53350,Q7Z460,P52732,Q9BT25,Q96Q89,Q96TC7,Q9P258,Q7Z4H7,O14965,Q13618,Q8IXJ6,Q8IX90,Q14203,Q14155,P28482,Q7Z5K2,Q99741,Q9HC35,O60610,Q9H8V3,Q00610,Q5SW79,Q15691,Q9BPX3 24 +Cell leading edge 0.2151319861487349 0.0916052380132939 0.9270116896192258 1.0 1.0 116 P47756,P41440,Q00535,Q9UQB8,Q8NCE2,Q9H6U6,Q6IBS0,P22392,Q16512,Q9UL63,O00401,P19174,P35241,Q96AC1,Q92974,P35579,O15357,P31751,Q86TI2,Q14155,Q9Y490,Q16513,Q92538,P50570,Q13153,P43034,Q03001,O60610,P15531,Q9Y5K6,Q9Y5X3,Q00534,Q9BPX3 33 +Supramolecular polymer 0.2823178897518446 0.0879936336460514 0.9298817361303028 1.0 1.0 232 Q00535,Q14331,Q9UQB8,Q7Z460,Q96IZ0,Q9BT25,Q9BUF5,P50748,Q9Y6D5,O60333,P13693,Q96CW5,Q99661,Q9P258,Q86TI2,P17987,P50570,P43034,Q14204,Q5SW79,O75880,Q9H6U6,Q9H6H4,Q9H0B6,Q6IBS0,Q96Q89,Q16512,O00401,P04075,P51114,Q9BTW9,Q96TC7,Q92974,Q08209,Q7Z4H7,Q9BSJ2,O43237,Q9HC35,Q13885,P63172,Q15691,P52732,P48643,P47756,Q6NUK4,Q16637,Q15813,O94967,P78559,Q9NZQ3,Q5VU43,Q9Y376,Q14008,O15344,O00429,P33176,P16949,P29372,P49368,P35579,Q99426,Q8IXJ6,Q13618,Q14203,Q13153,Q03001,P00568,Q13501,O43264,P15311,P68371,P60900,Q15555,Q14152,P36507,Q96AC1,Q66K74,O14965,P04350,P07437,Q9Y5K6,Q15058 82 +Anchoring junction 0.1664262532376058 0.0825736803928087 0.934190529790605 1.0 1.0 261 O00560,P84098,P62906,Q9UQB8,P17655,P60953,P61247,Q7Z460,P50395,P46940,P36578,Q7L576,Q5VW36,Q9HCM4,P11802,Q13418,P62241,Q96TA1,P11166,P61160,Q14155,Q99797,Q96HC4,P50570,P36404,Q14847,Q9UJW0,P42356,Q9Y613,P12814,Q9Y696,O43815,Q13177,O00192,Q02750,Q92796,P55196,P22392,P22314,Q16512,P62829,P22681,O15020,P32969,Q8WUM4,P35611,P62701,P08708,P39019,Q9BTW9,Q92974,Q08209,Q8TEW0,Q9UHD1,Q9NR12,P11940,Q99439,P0DMV9,P07384,Q9UEY8,O15145,Q16658,O14976,P05387,Q16513,P62899,P15880,Q07157,P62280,P39023,P46783,P62841,Q15691,Q8NI35,P41440,Q96N67,P27348,P63104,P62269,P35241,P61513,P35579,Q8IXJ6,Q13283,Q9Y490,Q9UNN8,Q13153,Q03001,Q9H8V3,P07737,P15311,Q00013,P62993,P31946,P62917,P41240,Q15555,P62081,Q9UHB9,P36507,Q96AC1,P78344,Q13045,P28482,Q9Y5K6,Q00610 106 +Transferase complex 0.2479743143152759 0.0793479773287082 0.9367558461797344 1.0 1.0 243 P29083,Q03164,Q00535,Q15369,Q96K76,Q92990,P25205,Q9NT62,O95067,Q99570,P18074,Q9BXJ9,Q9NW08,P49005,Q9UL63,Q14CX7,Q14999,Q13309,Q93100,Q9BUI4,O14802,O60566,Q9UJA5,P08237,P68036,P11802,P17858,Q96S59,O43318,Q8IWV7,Q86VP6,Q13617,Q99873,P49642,P28340,Q9UPT9,Q5TAQ9,Q9Y4B6,Q92759,P24386,P20248,Q08AM6,Q96P70,Q8IUR7,P57081,Q9UBP6,Q96T76,Q5VZE5,Q96BN8,Q6W2J9,P35269,Q07864,Q00534,O14744,Q5VTR2,P14635,Q16763 57 +Ciliary basal body 0.1999558081202197 0.0780417497631001 0.9377948427362246 1.0 1.0 17 Q9BZH6,Q9UPT5,Q13526,Q15154,Q96EX3,Q96C92,Q15691,P15311,Q9UIS9,P28070 10 +Leading edge membrane 0.2038330661726744 0.0745266003555967 0.9405913759940644 1.0 1.0 38 P50570,Q13153,P19174,P15531,O60610,P31751,Q96AC1,Q9Y490,Q16512,Q92974 10 +Neuron projection 0.2030082148283624 0.0743297964665747 0.9407479684507531 1.0 1.0 225 P11310,Q9Y3I1,Q00535,Q9UQB8,P17655,Q7Z460,Q15555,Q6IBS0,Q9UBF2,Q96Q89,P78559,Q16512,Q06787,Q9Y6D5,O60333,P22681,Q9BPU6,Q99996,P38935,Q96N67,P16949,Q08209,P40818,P21359,Q66K74,Q14790,Q9Y2T2,O14965,P04350,Q14155,Q9P265,P62753,Q9H269,P50570,Q9NZ32,P43034,Q9Y5K6,Q8TAG9,P42858,Q93008,Q9UBB6,P12277,Q14204,Q13614,P27695 45 +Perinuclear region of cytoplasm 0.2439997354876076 0.073609609430219 0.9413210246657626 1.0 1.0 194 P31946,Q8NCE2,P17655,P25205,Q14677,P20645,Q9BZF3,Q96Q89,Q06787,Q9H6S0,Q9Y6D5,Q14999,P22681,O00299,O60566,Q9Y487,P36507,O00429,P22059,P31689,Q9HAU5,Q99627,Q01105,Q9UII4,Q66K74,O14965,O95071,P30307,P62753,Q14240,O75569,Q7L5N1,P26572,P50570,Q9H4M9,P43034,Q92905,Q9Y5K6,P42858,Q9Y5X3,O75821,Q8NI35,Q13614,P27695 44 +Nuclear envelope lumen 0.268664542017015 0.0732213698885849 0.9416299613184878 1.0 1.0 4 P07437 1 +Guanyl nucleotide exchange factor complex 0.2482115675490978 0.0690064312509192 0.9449845003069766 1.0 1.0 5 Q9NR50,Q14185 2 +Transcription factor tftc complex 0.332935204538663 0.0687095542916351 0.9452208129546544 1.0 1.0 3 O75528,Q9Y4A5 2 +Cleavage furrow 0.1909998267474252 0.0666586882238095 0.9468534231466486 1.0 1.0 21 O75935,Q9H8V3,P35241,O95630,Q16512,Q16513 6 +Basal dendrite 0.5113432835820982 0.0663161317940722 0.9471261401820076 1.0 1.0 2 P46821 1 +Spindle 0.2168888065557304 0.0655484131525233 0.9477373610650206 1.0 1.0 158 P33981,P52732,Q7Z460,Q16539,Q15555,Q9BT25,P18074,Q92547,Q96Q89,P50748,Q9Y237,Q14166,Q14008,O76071,O60566,P13693,Q9NR09,O15344,Q96CW5,Q96BK5,Q96TC7,P29372,Q92974,Q99661,P35579,Q66K74,Q9P258,Q7Z4H7,Q9BVQ7,Q9Y5Y2,Q08J23,Q8IXJ6,Q13618,Q9BSJ2,Q9UJX4,Q13432,Q14203,Q14155,P28482,Q7Z5K2,Q96T76,Q9HC35,Q15691,P43034,O75935,Q99986,O60610,Q9H8V3,Q15058,O75351,O43264,P63172,Q5SW79,Q15398,P14635,O14965,Q9BPX3 57 +Cell substrate junction 0.1740348704691471 0.0651055898217701 0.9480899298434208 1.0 1.0 185 O00560,P84098,P41440,P15311,P31946,P62917,P62906,P17655,P60953,P61247,Q7Z460,Q15555,P50395,P46940,P36578,Q02750,P22392,P62829,Q16512,Q7L576,P22681,Q5VW36,P62081,Q9UHB9,Q96N67,P27348,P32969,P63104,Q9HCM4,Q8WUM4,P35611,P62701,P36507,P08708,Q13418,P62241,P39019,P62269,P35241,Q96AC1,P61513,Q92974,Q9UHD1,Q9NR12,P35579,P11940,Q13045,Q99439,P61160,P0DMV9,P07384,Q13283,Q14155,O15145,P05387,Q9Y490,P28482,Q9UNN8,P62899,P15880,P07737,P50570,Q13153,P36404,Q14847,Q03001,Q9UJW0,P39023,Q00610,P46783,P42356,P62841,Q15691,P12814 74 +Lamellipodium 0.1591302486711697 0.0642904762878365 0.9487389365893706 1.0 1.0 67 P41440,O00401,Q00535,O15357,Q9UQB8,P50570,P19174,Q6IBS0,Q14155,P22392,Q96AC1,Q16512,Q16513,Q9BPX3 14 +Torc1 complex 0.5071641791044865 0.0639867904667738 0.9489807449332708 1.0 1.0 2 Q9Y4R8 1 +Tor complex 0.5071641791044865 0.0639867904667738 0.9489807449332708 1.0 1.0 2 Q9Y4R8 1 +Chromosomal region 0.1397625281201421 0.0618499616550387 0.950682315969295 1.0 1.0 171 P33981,P53350,Q7Z460,P25205,Q9HBM1,Q9BUR4,P42695,Q92900,Q9UER7,Q6P1K2,Q96DY7,O96017,P50748,Q06787,Q9Y6G9,Q14008,O60566,Q9NRZ9,O14980,O43684,O14929,P26358,P39748,Q8IWS0,Q96BK5,Q99661,Q2NKX8,P28340,Q9UBD5,Q9H900,O43683,P33991,Q9P258,Q8IXJ6,Q14141,P43246,P05455,Q14203,Q8IX90,Q92674,Q9NTJ3,O43237,Q7Z5K2,Q13535,P43034,O75935,Q15021,O43264,P14635,Q9BPX3,P27695 51 +Tight junction 0.18948426383445 0.0606407155063005 0.951645346887842 1.0 1.0 29 Q9H8V3,P11802,Q9BTW9,Q92796,Q92974,Q8NI35 6 +Ribosomal subunit 0.1898155869287732 0.0598554157330974 0.9522707892811432 1.0 1.0 117 P46776,P84098,P62750,P60866,P62917,P62906,P61254,P61247,P50914,P46778,Q7Z478,P62081,P32969,P62701,P27635,P62847,P08708,P62854,Q7Z7F7,P42766,P39019,P62269,P61513,P51116,Q9BY44,P47914,P83731,Q567V2,P05387,P62753,P18621,P62899,P15880,P05198,Q9HD33,P39023,P62266,P46783,P62841 39 +Large ribosomal subunit 0.1587119067364609 0.0593042802900184 0.9527097519390562 1.0 1.0 71 P46776,P84098,P62750,P62917,P62906,P61254,P50914,P46778,P32969,P27635,Q7Z7F7,P42766,P61513,P51116,P47914,P83731,Q567V2,P05387,P18621,P62899,Q9HD33,P39023 22 +Ribosome 0.1870279643500477 0.0566599308987406 0.9548160932212636 1.0 1.0 134 P46776,P84098,P62750,P60866,P62917,P62906,P61254,P61247,P50914,P46778,Q7Z478,P62081,Q9UHB9,P32969,P62701,P27635,P62847,P08708,P62854,Q7Z7F7,P42766,P39019,P62269,P61513,P51116,Q9BY44,P47914,Q6PKG0,P83731,Q567V2,P05387,P62753,Q92616,P18621,P62899,P15880,P05198,Q9HD33,P39023,P62266,P46783,P62841,Q0VDF9,P20290,P27695 45 +Actin cytoskeleton 0.1809342375479877 0.056457490560341 0.9549773590993728 1.0 1.0 142 P47756,Q9Y696,P41440,Q9UQB8,P17655,Q96IZ0,Q6IBS0,Q92547,Q92614,Q16512,P50748,P47755,O15020,O00401,P04075,P35611,P35241,Q96AC1,P60981,P35579,Q99439,Q15334,A1X283,O75607,Q9NZ32,Q13153,O75935,Q9Y5K6,Q9Y613,Q9BPX3,P27695 31 +Chromosome centromeric region 0.1716648983215855 0.0540241247438258 0.956915943539354 1.0 1.0 100 P33981,P53350,Q7Z460,Q9HBM1,P42695,Q9UER7,Q6P1K2,P50748,Q96DY7,Q06787,Q9Y6G9,Q14008,O60566,Q9NRZ9,O14980,O43684,P26358,Q8IWS0,Q96BK5,Q2NKX8,Q99661,O43683,Q9H900,Q9P258,Q14141,Q14203,Q8IX90,Q92674,Q9NTJ3,O43237,Q7Z5K2,P43034,O75935,Q15021,O43264,P14635,Q9BPX3 37 +Cell cell junction 0.1655307637780413 0.0516379514293985 0.9588171787971096 1.0 1.0 120 Q9Y696,P41440,Q9UQB8,P41240,Q92796,P22314,Q16512,O15020,P35611,P36507,P11802,Q9BTW9,P35241,Q96AC1,Q92974,Q96TA1,Q08209,Q8TEW0,P35579,Q99439,Q8IXJ6,Q9UEY8,Q9Y490,Q16513,Q13153,Q9H8V3,Q9Y5K6,Q9Y613,P15311,Q8NI35,Q00013 31 +Cd40 receptor complex 0.2971036130188039 0.0515617695764032 0.9588778822547352 1.0 1.0 3 Q12933,O15111 2 +Cell cortex 0.1677264695976085 0.0514421111909609 0.9589732292974796 1.0 1.0 105 P47756,P41440,Q9P0V9,P17655,Q7Z460,Q96KP1,Q9UL63,P47755,O15020,O00401,P35241,Q96AC1,P60981,Q8TEW0,P35579,P31751,Q15334,Q14203,Q9UEY8,Q14155,P43034,Q03001,Q9H8V3,Q8TAG9,Q14204,P07737,Q15691,P15311 28 +Actomyosin 0.1554363754450913 0.04957028115706 0.9604648297070232 1.0 1.0 29 Q9NR12,P35579,Q99439,Q8WUM4,Q9UJW0,Q9UHD8,Q13418,Q92614,Q96HC4,Q96AC1,Q9Y613,P12814 12 +Actin filament bundle 0.1014272258112673 0.0470498663931143 0.9624734838727502 1.0 1.0 29 Q9NR12,P35579,Q99439,Q9UJW0,Q9UHD8,Q13418,Q96HC4,Q96AC1,Q9Y613,P12814 10 +Adherens junction 0.1509287196760604 0.0467749636134249 0.962692583328732 1.0 1.0 51 O00560,P41440,Q9UQB8,O00192,P26038,P55196,Q9HCM4,P35611,P78310,P62136,Q92597,Q9BTW9,Q96AC1,P35241,Q96TA1,Q8TEW0,Q9NR12,P78344,P35579,Q9P1Y5,Q96HC4,Q9Y490,Q07157,P15311 24 +Actin filament 0.1282566994336521 0.0445712378911942 0.964449068705465 1.0 1.0 36 Q9NR12,Q9Y2A7,O00401,Q9UM54,Q14195,P15311,Q13153,Q9Y5K6,Q9UJU6,Q96IZ0,P46940,Q6IBS0,Q96HC4,P07947,Q16512,P12814 16 +Rna polymerase ii transcription repressor complex 0.3394029850746313 0.0312096247313296 0.9751023642290158 1.0 1.0 2 Q9UHI6 1 +Compact myelin 0.3095522388059754 0.0307878824550232 0.97543870424022 1.0 1.0 2 Q8IXJ6 1 +Golgi cis cisterna 0.2826865671641851 0.0306395251258582 0.9755570204436644 1.0 1.0 2 Q15334 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fa3658d32a95627c7f1ace78e591772a8b9d0dcb --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bbsome", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor disc membrane", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Symmetric synapse", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CASP3", "CASP8", "CASP8AP2", "CAST", "CBL", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMPR2", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXA10", "HOXD11", "HP1BP3", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ITCH", "ITGB1", "ITPK1", "ITPR2", "ITSN2", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MGA", "MGAT1", "MGAT5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMP1", "NENF", "NES", "NF1", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPM3", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTULIN", "OXA1L", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPM1L", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPN13", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS2", "TBC1D23", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE4", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", 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sha256:644a1c9a57851d4e8d15186d0a54a9d4c34b2a9df47e255a1be18e352af7d9c8 +size 150251 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..7e9da6f791c67459fab493c79657f75195599859 --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a58ea273a92591d40410fe57ddfda4ec53fe2b360ded512eee7bb3a0a80f0867 +size 147534 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..03fee0bf5b72516e3c074873a7961bed93b1de5a --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e3bd6573fb5c2561f88845d8ca9c28ac76d132f84a20e5ea625ffc7d589ca39 +size 141803 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3d22402bf022b6588a0b01377c051eacb2ade451 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a63a426b5062022b4bfba9619c201ebe885bd530c43500ae40e01224bf7c0dab +size 125851 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..76533a62989ea0f8d79a31d49d88dd2a8874b04d --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,29 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Translation factor activity rna binding 35 56 3.697683850458959 0.0002175756299696 20.436893203883496 53.987864077669904 -0.3875060502954274 0.548917367166947 8.785104232007459 2.1344034206559086 1.1881193244272017 0.366265044062608 0.3035469874952778 0.1670251985667709 0.0110083802883316 2.3315619029551103e-08 +Transferase activity transferring one carbon groups 25 68 3.432661346710806 0.0005976881367657 15.330097087378642 60.89320388349515 -0.0477714165453824 0.6328340990686153 8.505438978887788 9.11113968909267 0.8654901708448212 0.3212092574275675 0.2079589738626584 0.0296634604884568 0.0016047043394935 0.0036027219765712 +Translation regulator activity nucleic acid binding 37 65 3.315535369666036 0.0009146776541641 20.885922330097088 62.970873786407765 -0.2153316283409681 0.5810585562874645 10.014266322329854 2.613283136412972 1.123797243693277 0.357239690044585 0.350559181402426 0.2181701792989502 0.0243370767626102 1.4094729112069168e-08 +Endopeptidase activity 25 66 3.179088468436724 0.0014773899201752 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0070129376191478 0.0009448722095545 0.0021956773575315 5.16657001104453e-05 +Protein serine kinase activity 40 72 3.154008280509936 0.0016104451629921 18.606796116504853 58.79368932038835 -0.2547746046050501 0.5863977102077378 8.497901078786414 12.25769657088421 0.9472615480729644 0.3269248883217332 0.7215494755704439 0.2558161325510135 0.6453569989292032 0.5696776559181163 +Protein serine threonine tyrosine kinase activity 41 76 2.7815395226037247 0.0054101742732348 19.475728155339805 63.939320388349515 -0.3064367199223224 0.6001763214586637 8.904122161116224 13.055843743274796 0.8725878237254184 0.322654526690802 0.7784148479961035 0.3578283145658334 0.7888056899830241 0.699613558143403 +Translation regulator activity 42 81 2.6887121171137887 0.0071728248299383 25.199029126213592 78.43203883495146 -0.1449572932869035 0.5916688790638589 11.530424045500434 2.964636672584618 1.1118561159381193 0.3577333285619786 0.4247960252144678 0.3088899575674019 0.0668974023831436 2.2960543316699705e-07 +S adenosylmethionine dependent methyltransferase activity 19 50 2.5098979211636947 0.0120766066160933 11.604368932038836 44.76699029126213 -0.0344811954285482 0.6338204342811783 6.857161258427814 7.630996936352693 0.8219252079821918 0.314473491654849 0.4761861866414922 0.1430247551238553 0.0018899670173545 0.0075219453181124 +Protein serine threonine kinase activity 46 87 2.423869313346564 0.015356130477137 21.385922330097088 69.94902912621359 -0.2265230805291581 0.6116443932751089 9.55815596799563 14.238769174373656 0.8662596685370179 0.315939433499304 0.7784148479961035 0.3578283145658334 0.6566759746273048 0.5991478676694187 +Trna methyltransferase activity 8 12 2.3953847162574027 0.0166029344249358 3.0145631067961167 8.354368932038835 0.0860527239710543 0.5964711998733863 2.1519423498517547 2.316185208946292 0.8346999218487118 0.2982134343185151 1.0 0.2615377882636782 0.0068941903455315 0.003914644875648 +Dna directed dna polymerase activity 1 6 2.3795245608368893 0.0173349877614992 2.9199029126213594 7.495145631067961 0.1147726318284263 0.586152160764852 2.064703836467016 1.4287192065009142 0.8321595329711028 0.2979673720697421 1.0 1.0 0.1046379555654025 0.3080842130268088 +Ubiquitin like protein transferase activity 35 76 2.299886165901479 0.0214546700532767 20.140776699029125 63.69174757281554 -0.4203822608145132 0.5356722361377586 9.237407454698385 13.5494287435333 1.0516346378201498 0.3513436211625634 0.7794694811281373 0.8116759450015218 0.512771661856204 0.1031747739181671 +Cysteine type peptidase activity 19 51 2.2997600456303453 0.0214618181882213 12.109223300970871 44.08495145631068 -0.1451192974466758 0.596001868152635 6.000017182713323 7.277780171243459 0.8950128681796422 0.3160523160059556 0.137485864642348 0.0105379818243148 0.0068997872780318 0.0013137241116572 +Translation initiation factor activity 24 39 2.2923086240449524 0.0218878405369178 12.41504854368932 36.407766990291265 -0.0620726684038362 0.6020098880208691 6.262080887091644 1.941808251479095 1.008453552811725 0.334422762452143 0.1955906255262107 0.0721769910266099 0.0008515908739311 1.6541310305875818e-06 +Catalytic activity acting on a trna 27 66 2.2630675878604083 0.0236315232049637 22.354368932038835 56.01456310679612 -0.7391235816572294 0.4996495027105387 8.127363306170771 6.915915340958064 1.015429315694999 0.3463696280095691 0.4247960252144678 0.3088899575674019 0.0668974023831436 0.0296324683723188 +Amp binding 5 7 2.2397724634740817 0.0251056984290121 3.949029126213592 6.679611650485437 -0.3647231439530235 0.5159441234178384 1.7445682775058762 0.6108023091272167 0.8768979051282072 0.3040687119573487 1.0 1.0 0.2348471946143729 0.0013781701696679 +Trna guanine methyltransferase activity 4 8 2.2315435739080893 0.025645144543386 2.7233009708737863 6.497572815533981 -0.1271505430098403 0.5730507027541544 1.8317959717807184 1.7200965010292992 0.8507515845399768 0.3030817794917143 1.0 0.1157837219692003 0.0001960616495152 0.0002457979454447 +Proteasome binding 6 11 2.200050006029548 0.0278033473350727 2.9344660194174756 10.58980582524272 0.3784148328441568 0.5391220092078972 1.7853439081041342 1.2956959973836335 0.8542320107205437 0.3003434060811568 1.0 1.0 0.0060877577335729 0.0062633876942655 +Growth factor activity 0 6 2.15864143874804 0.030877995268516 1.5048543689320388 5.609223300970874 0.2855357944033511 0.4112481245541766 1.5971685286433237 0.8786642436387735 1.1447785466231724 0.3004578148722612 0.1092078710908161 0.2108364442764713 0.4559893986318888 0.7122509845733965 +Histone methyltransferase activity h3 k4 specific 1 6 2.1540279055175984 0.031237983573563 2.4684466019417477 5.633495145631068 -0.2722540097650233 0.4999812868506373 1.7212195142051714 1.22440570782526 0.9291495851091338 0.2992737636331039 0.0626754461774391 0.0074166479276302 0.0432719236791885 0.1457988469723397 +Ubiquitin like protein conjugating enzyme activity 6 8 2.145236665760322 0.0319339294185023 3.703883495145631 7.898058252427185 -0.1947000064283374 0.5406957224860515 2.1337974867784335 1.238263784696197 0.8878473245914655 0.291446168478197 0.1376340872498759 0.2615377882636782 0.5413730864422689 0.0179733508374719 +Dynactin binding 3 6 2.143535911770708 0.0320700906566813 2.150485436893204 5.584951456310679 0.2775355704886244 0.5227141328346228 1.318897287741983 1.161713977954793 0.9194793023459098 0.3062784805257165 1.0 1.0 0.2159896916124382 0.0817606313480972 +Plus end directed microtubule motor activity 4 7 2.0935953189923264 0.0362960449113713 2.3276699029126213 5.618932038834951 0.0949964055913641 0.5576757090061089 1.606090171381647 1.6903296700465067 0.8958973981997931 0.3052446097230289 1.0 1.0 0.3225700131084155 0.5492603500015365 +Histone methyltransferase activity 2 20 2.0157480412008333 0.0438263292666638 5.097087378640777 18.237864077669904 0.1244895512019806 0.4941614121988424 3.313006328716042 3.142524385825145 1.057643161070896 0.3213310584694642 0.0246888623572726 0.0134897524236001 0.1343608611761769 0.1132481709467278 +Organic cation transmembrane transporter activity 1 5 2.00175265226113 0.0453113405245044 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 0.0018270290105774 0.0074166479276302 0.0432719236791885 0.1457988469723397 +Atp dependent peptidase activity 0 5 1.9770330335447743 0.0480378963634327 1.91747572815534 5.179611650485437 0.3096816660551942 0.4263179137334537 1.572823025272822 0.3901354565114186 1.104598172623402 0.3112103230891728 0.0318339803833352 0.0640938023600107 0.1565948204648432 0.2942334307578267 +Pre mirna binding 1 6 1.9758142226454445 0.0481758219949899 2.395631067961165 4.645631067961165 0.0451174645519511 0.5714751002964188 1.4112173151187923 0.7699800399668832 0.8626355963307901 0.3053316374984833 1.0 0.0012840094904148 0.0080925194523707 0.0309764532364539 +Cyclin dependent protein serine threonine kinase regulator activity 5 9 1.960600452328564 0.0499256495803688 2.4805825242718447 5.519417475728155 0.228341462053297 0.5714132507541911 1.69582916411688 1.600094551358398 0.8688933058851026 0.3181784185621054 1.0 1.0 0.6038468593666926 0.0353817250131281 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9f36886b3d7cdca9ae44fcd150c452162e849339 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 1394, + "title": "Average number of proteins per term", + "value": 17.371592539454806 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c49b251b05f3738ec903b7c73aba9f50102d45a7 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..700397e2f035a85742fda786619a157585ccf4b8 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,471 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Translation factor activity rna binding 0.5179912600161025 3.697683850458959 0.0002175756299696 0.2616471324593048 0.2166401766203697 56 P49770,Q05639,Q15056,Q14232,Q9ULC4,Q7Z2Z2,P29692,P41567,Q14152,Q7Z478,O60841,P62495,P46199,O43432,O15371,O00178,P78344,Q9BY44,Q13144,Q9Y262,P41214,P63241,P13639,Q04637,Q14240,Q92616,P05198,Q9NR50,Q8NE71,Q92905,P06730,Q9Y450,O60573,O75821,P26641 35 +Transferase activity transferring one carbon groups 0.4941757712103434 3.432661346710806 0.0005976881367657 0.5654422153548231 0.2166401766203697 68 Q03164,Q8NCA5,Q9BV86,Q9BV44,Q7L2J0,Q7Z2T5,Q14353,O60725,P26358,Q86TU7,Q99873,P31939,Q99707,O60294,Q08J23,O60678,Q7Z4G4,Q8TEA1,P57081,Q8N1G2,Q9UBP6,Q9H993,Q96P11,O14744,Q86W50 25 +Translation regulator activity nucleic acid binding 0.4789358348344945 3.315535369666036 0.0009146776541641 0.7207489666181446 0.2166401766203697 65 P49770,Q05639,Q15056,Q14232,Q9ULC4,Q7Z2Z2,P29692,P41567,Q14152,Q7Z478,O60841,P62495,P46199,O43432,O15371,O00178,P78344,Q9BY44,Q6PKG0,Q13144,Q9Y262,P41214,P00374,P63241,Q04637,P13639,Q14240,Q92616,P05198,Q9NR50,Q8NE71,Q92905,P06730,Q9Y450,O60573,O75821,P26641 37 +Endopeptidase activity 0.468041773746188 3.179088468436724 0.0014773899201752 0.8726739777305315 0.2806200696513798 66 Q16740,P55210,P60900,Q96K76,P17655,Q9Y4P1,P51784,P20618,P48147,P49720,Q96RU2,P28070,P49721,P40818,Q4J6C6,O43847,Q14790,P55212,P14735,Q86UV5,Q92905,Q93008,P28074,P52888,P42574 25 +Protein serine kinase activity 0.4745567969298384 3.154008280509936 0.0016104451629921 0.8942598059787842 0.2806200696513798 72 P49761,Q00535,P33981,P53350,Q7Z460,Q8TD19,P52564,Q16539,Q99570,Q96KB5,O75116,Q13546,Q16512,O96017,O60566,P36507,P11802,O43318,Q96SB4,P19784,P78362,O43683,Q13555,Q13464,Q13043,O14965,Q9Y4B6,P31751,P28482,Q16513,Q14012,Q13535,Q13153,P45985,Q99986,Q9NYV4,Q9UHD2,Q9H2G2,Q00534,P17612 40 +Protein serine threonine tyrosine kinase activity 0.447012819028537 2.7815395226037247 0.0054101742732348 0.999480299565242 0.5733066159461302 76 P49761,Q00535,P33981,P53350,Q7Z460,P41240,Q8TD19,P52564,Q16539,Q99570,Q96KB5,O75116,Q13546,Q16512,O96017,O60566,P36507,P11802,O43318,Q96SB4,P19784,P78362,O43683,Q13555,Q13464,Q13043,O14965,Q9Y4B6,P31751,P28482,Q16513,Q14012,Q13535,Q13153,P45985,Q99986,Q9NYV4,Q9UHD2,Q9H2G2,Q00534,P17612 41 +Translation regulator activity 0.4457719400792086 2.6887121171137887 0.0071728248299383 0.9999561594102562 0.5733066159461302 81 P49770,Q05639,Q15056,Q14232,Q9ULC4,P29692,Q7Z2Z2,Q06787,P41567,Q14152,Q7Z478,O60841,P27635,P62495,P46199,P51114,O43432,O15371,O00178,P51116,Q9BY44,P78344,Q6PKG0,Q13144,Q9Y262,P41214,Q5PRF9,P00374,P63241,P13639,Q04637,Q14240,Q92616,P05198,Q9NR50,Q8NE71,Q92905,P06730,Q9Y450,O60573,O75821,P26641 42 +S adenosylmethionine dependent methyltransferase activity 0.4768467141623366 2.5098979211636947 0.0120766066160933 0.9999999559204154 0.5733066159461302 50 Q03164,Q9BV44,Q7L2J0,Q7Z2T5,Q14353,O60725,P26358,Q86TU7,Q99873,Q08J23,O60678,Q7Z4G4,Q8TEA1,P57081,Q8N1G2,Q9UBP6,Q9H993,O14744,Q86W50 19 +Protein serine threonine kinase activity 0.430756242025834 2.423869313346564 0.015356130477137 0.9999999995722612 0.5733066159461302 87 P49761,Q00535,P33981,P53350,Q7Z460,Q8TD19,P52564,Q16539,Q99570,Q96KB5,O75116,Q16512,O96017,Q13546,O15111,O60566,P36507,P11802,O43318,P25440,P67870,Q96SB4,P19784,P78362,Q8IV63,O43683,Q13555,Q13464,Q13043,O14965,Q9Y4B6,P31751,P28482,Q16513,Q14012,Q13535,P45985,Q13153,Q99986,Q9NYV4,Q9UHD2,O75909,Q9H2G2,Q00534,Q13501,P17612 46 +Trna methyltransferase activity 0.6829078640618027 2.3953847162574027 0.0166029344249358 0.9999999999268696 0.5733066159461302 12 Q9UBP6,O60294,Q08J23,Q9BV44,Q7Z4G4,Q7Z2T5,Q8TEA1,P57081 8 +Dna directed dna polymerase activity 0.8078776625401889 2.3795245608368893 0.0173349877614992 0.9999999999741024 0.5733066159461302 6 P28340 1 +Ubiquitin like protein transferase activity 0.4053899476355939 2.299886165901479 0.0214546700532767 0.999999999999926 0.5733066159461302 76 Q9Y3I1,Q5T4S7,Q7Z6Z7,Q93034,Q9NT62,Q14258,Q9H1B7,Q9UPN9,P22681,Q9NR09,Q9Y314,P68036,P61081,P49427,Q8IWV7,P19474,Q15386,Q8N806,Q9UII4,Q9C0C9,Q9ULT8,Q8TBC4,Q13618,O95071,P61086,Q05086,O95376,Q7Z7E8,O95628,Q6W2J9,O94822,Q5VTR2,Q96JP5,Q14527,Q16763 35 +Cysteine type peptidase activity 0.4448615521930101 2.2997600456303453 0.0214618181882213 0.9999999999999266 0.5733066159461302 51 P55210,Q96K76,P17655,Q9Y4P1,P51784,Q96FW1,Q96RU2,P40818,Q9UPT9,Q14790,P55212,Q7L5N1,Q86UV5,Q92905,Q96BN8,Q9NUQ7,P42574,O95630,Q01804 19 +Translation initiation factor activity 0.5507199550731203 2.2923086240449524 0.0218878405369178 0.99999999999996 0.5733066159461302 39 P49770,Q15056,Q14232,Q9ULC4,P41567,Q14152,Q7Z478,O60841,P46199,O43432,O15371,P78344,Q9BY44,Q13144,Q9Y262,P41214,Q04637,Q14240,P05198,Q9NR50,Q92905,P06730,O60573,O75821 24 +Catalytic activity acting on a trna 0.3885193414649193 2.2630675878604083 0.0236315232049637 0.9999999999999968 0.5733066159461302 66 Q9P2J5,Q9C0B1,O15091,Q9BV44,P54136,Q7Z2T5,P26639,P07814,O75818,P47897,P41252,P54577,Q9NSD9,Q96I59,O43776,O60294,Q08J23,Q9UET6,Q7Z4G4,Q8TEA1,P57081,Q6P1R4,Q9UBP6,P26640,Q99575,P49589,Q9Y285 27 +Amp binding 0.7464318258108005 2.2397724634740817 0.0251056984290121 0.9999999999999996 0.5733066159461302 7 P08237,P17858,P06737,P07741,Q01813 5 +Trna guanine methyltransferase activity 0.7145178217063755 2.2315435739080893 0.025645144543386 0.9999999999999998 0.5733066159461302 8 Q9UBP6,Q7Z2T5,P57081,Q7Z4G4 4 +Proteasome binding 0.6471683632429731 2.200050006029548 0.0278033473350727 1.0 0.5733066159461302 11 Q16186,O95456,Q14997,Q5VYK3,P46379,O00487 6 +Cysteine type endopeptidase activity involved in apoptotic process 0.8473715651134954 2.198746487402937 0.0278959534446994 1.0 0.5733066159461302 4 P55212,P42574,Q14790 3 +Histone methyltransferase activity h3 k4 specific 0.7572603875002293 2.1540279055175984 0.031237983573563 1.0 0.5733066159461302 6 Q03164 1 +Ubiquitin like protein conjugating enzyme activity 0.696855418076481 2.145236665760322 0.0319339294185023 1.0 0.5733066159461302 8 Q9C0C9,Q9NR09,P68036,P49427,Q16763,Q7Z7E8 6 +Dynactin binding 0.7549353998869838 2.143535911770708 0.0320700906566813 1.0 0.5733066159461302 6 Q9Y5X3,P42858,P43034 3 +Plus end directed microtubule motor activity 0.7152765414318731 2.0935953189923264 0.0362960449113713 1.0 0.5733066159461302 7 Q96Q89,P52732,Q15058,O60333 4 +Histone methyltransferase activity 0.6020345721333572 2.0157480412008333 0.0438263292666638 1.0 0.5733066159461302 20 Q03164,Q9BV86 2 +Organic cation transmembrane transporter activity 0.7618437830561813 2.00175265226113 0.0453113405245044 1.0 0.5733066159461302 5 Q70HW3 1 +Dna n glycosylase activity 0.7967791668781095 1.984636459422838 0.0471849328759486 1.0 0.5733066159461302 4 P29372 1 +Pre mirna binding 0.7181079190192932 1.9758142226454445 0.0481758219949899 1.0 0.5733066159461302 6 Q9HAV4 1 +Cyclin dependent protein serine threonine kinase regulator activity 0.6315658232381615 1.960600452328564 0.0499256495803688 1.0 0.5733066159461302 9 O95067,P42771,P20248,P42574,P14635 5 +S methyltransferase activity 0.9422636535742388 1.9440744379459367 0.051886475280988 1.0 0.5733066159461302 3 Q03164 1 +Microtubule binding 0.376532705937724 1.9409564558359824 0.0522635592725813 1.0 0.5733066159461302 77 Q9Y295,Q00535,Q6NUK4,Q7Z460,Q9H6H4,Q15555,Q9BT25,Q96Q89,P78559,Q06787,O60333,Q14008,Q9BPU6,Q9UH99,O15344,O00429,Q96CW5,P33176,Q96TC7,P29372,Q92974,Q99661,Q66K74,Q9P258,Q7Z4H7,Q9BSJ2,Q14203,Q9HC35,Q15691,P50570,P43034,Q03001,Q15058,Q15398,P15311,P52732 36 +Ubiquitin like modifier activating enzyme activity 0.682511210762338 1.937479820025199 0.0526867178213308 1.0 0.5733066159461302 7 Q8TBC4,Q9UBT2,A0AVT1,P22314,Q13564,O95352 6 +Phosphatidylinositol 3 5 bisphosphate binding 0.7084028861032203 1.9311480283513889 0.0534647489763249 1.0 0.5733066159461302 6 Q9Y5X3,Q92538,A1X283,O60493 4 +Threonine type endopeptidase activity 0.6465547742034614 1.8952492006595416 0.0580593947101548 1.0 0.5887398468642214 8 P49720,P28074,P20618,P28070,P49721 5 +Threonine type peptidase activity 0.6181809132997343 1.8903957657932 0.0587050492927738 1.0 0.5887398468642214 9 P49720,P28074,P20618,P28070,P49721 5 +Hydrolase activity hydrolyzing n glycosyl compounds 0.6682674173480748 1.8688871190363985 0.0616385207676319 1.0 0.5925799858626137 7 P29372,P27695 2 +Rna methyltransferase activity 0.5611887890170835 1.8501158504388948 0.0642968538858266 1.0 0.6026400243768651 25 Q8N1G2,Q9UBP6,O60294,Q08J23,Q96P11,Q86W50,Q9BV44,Q7Z4G4,Q7L2J0,Q7Z2T5,Q8TEA1,P57081 12 +5 3 dna helicase activity 0.7270157650981295 1.84671435143402 0.0647885506123557 1.0 0.6026400243768651 5 P38935 1 +Phosphotyrosine residue binding 0.6368448340113558 1.84631495487631 0.0648464875584862 1.0 0.6026400243768651 8 P46109,Q06124,P28482,P07737,P22681 5 +Dna secondary structure binding 0.5800050992210023 1.8323767159151767 0.0668953146005861 1.0 0.6110475585442121 10 Q03164,P09429 2 +Ubiquitin protein transferase regulator activity 0.57645975307723 1.8127115509880956 0.0698763219775702 1.0 0.6136536204061195 10 Q92990,P62081,P68036,P60866 4 +Microtubule plus end binding 0.6005604855300113 1.7973225828995534 0.0722844230916979 1.0 0.6136536204061195 9 Q14008,P43034,Q7Z460,Q15555,Q14203,Q15691,Q99661 7 +Endopeptidase activator activity 0.7146247476279481 1.791051414969537 0.0732850446849409 1.0 0.6136536204061195 5 P61289,O00487 2 +Dipeptidyl peptidase activity 0.9003081052727175 1.784915701376612 0.074274991437838 1.0 0.6136536204061195 3 Q86TI2 1 +Sh3 domain binding 0.5635873156771869 1.7846462081124417 0.0743187212697651 1.0 0.6136536204061195 20 P22681,P50570,O15357,Q96T51,Q9Y5K6,Q16204,Q14185,Q96D71,Q96PU8,Q9NZQ3,P40818 11 +Hydrolase activity acting on ether bonds 0.6719102320381787 1.761563304093415 0.0781431085316379 1.0 0.6136536204061195 6 P09960,Q9H4A4,O43488,P07099 4 +Phosphatidylinositol 5 phosphate binding 0.8907136458644384 1.7482735637132436 0.0804166686448881 1.0 0.6159386598405171 3 O60493,A1X283 2 +Rna dna hybrid ribonuclease activity 0.7380525686977198 1.730856496928604 0.0834773623271436 1.0 0.6249909972595732 4 Q9UQ84,P39748,P27695 3 +Trna binding 0.4300478206863688 1.7307276595573269 0.0835003495598236 1.0 0.6249909972595732 46 Q9BY44,Q9UBP6,P38935,P26639,Q08J23,O95163,P05455,P49589,Q2VPK5,P41252,Q7Z4G4,Q8TEA1,P54136,Q7Z2T5,Q9HAV4,Q9Y285,Q7Z7L1 17 +Ribosomal small subunit binding 0.5617537993440733 1.7282014642582209 0.0839521113178285 1.0 0.6249909972595732 12 Q7Z478,P61221,P15531,P46199,P41567 5 +Proline rich region binding 0.7353643966547085 1.71912028551777 0.0855924717864291 1.0 0.6249909972595732 4 P41240,Q6Y7W6,Q9UQB8 3 +Protein methyltransferase activity 0.5324906379203389 1.707149045034786 0.0877943531425768 1.0 0.6249909972595732 27 Q03164,Q9BV86 2 +Protein tyrosine serine threonine phosphatase activity 0.6345659553493472 1.7049852698831431 0.0881971716786045 1.0 0.6249909972595732 7 Q13614,Q9UNI6,O60942,Q99956 4 +Histone lysine n methyltransferase activity 0.5566456826792128 1.6996734204196329 0.0891923715878402 1.0 0.6249909972595732 13 Q03164 1 +Lysine n methyltransferase activity 0.5566456826792128 1.6996734204196329 0.0891923715878402 1.0 0.6249909972595732 13 Q03164 1 +Ubiquitin like protein ligase activity 0.3926108868579201 1.68089727557725 0.0927828692574568 1.0 0.6249909972595732 50 Q5T4S7,Q7Z6Z7,Q14258,Q9H1B7,P22681,Q9Y314,Q8IWV7,P19474,Q15386,Q8N806,Q9UII4,Q9C0C9,Q9ULT8,Q13618,O95071,P61086,Q05086,O95376,O94822,Q5VTR2,Q14527 21 +Protein phosphorylated amino acid binding 0.5520889961075875 1.673322380374612 0.0942638489308007 1.0 0.6249909972595732 12 P62993,P31946,P46109,Q06124,P28482,P07737,P22681 7 +Epoxide hydrolase activity 0.7244063291793411 1.6711833345178857 0.0946854709938072 1.0 0.6249909972595732 4 P07099,P09960 2 +Ether hydrolase activity 0.7244063291793411 1.6711833345178857 0.0946854709938072 1.0 0.6249909972595732 4 P07099,P09960 2 +Rna polymerase ii general transcription initiation factor activity 0.6272283183283603 1.6690252011455442 0.0951123855153537 1.0 0.6249909972595732 7 Q92759,P35269 2 +Tubulin binding 0.388601603667892 1.6684916319568115 0.0952181717171167 1.0 0.6249909972595732 105 Q9Y295,Q00535,Q6NUK4,Q7Z460,Q9H6U6,Q9H6H4,Q15555,Q15813,Q9BT25,Q96Q89,O14737,P78559,Q16512,Q06787,O60333,Q14166,Q14008,Q9BPU6,P04075,Q9UH99,O15344,O00429,Q96CW5,P33176,P16949,Q8IWS0,Q9BTW9,Q96TC7,P29372,Q92974,Q99661,Q66K74,Q9P258,Q7Z4H7,Q9BSJ2,Q14203,Q14155,Q9P265,Q9HC35,Q15691,P50570,Q13153,P43034,Q03001,Q15058,P42858,Q15398,P15311,P52732,P48643 50 +Signaling receptor regulator activity 0.5481074536195153 1.664740464773954 0.0959645462153047 1.0 0.6249909972595732 17 P09429,P43490,Q9UMX5,Q00535 4 +Phosphatidylinositol bisphosphate binding 0.5435762991495054 1.6446973840965615 0.1000322325553111 1.0 0.6249909972595732 18 Q92538,Q9BPX3,Q13045,Q9Y4P8,Q9Y5X3,Q6IBS0,O60493,A1X283,P35080,Q9BTX7,P07737,Q8TEW0 12 +Aminopeptidase activity 0.542676039087148 1.6232460592420204 0.1045368153511627 1.0 0.6249909972595732 15 P09960,Q9NY33,Q86TI2,P55786,P50579,Q9H4A4 6 +Carbohydrate kinase activity 0.5917236211441043 1.616411057074875 0.1060054693239909 1.0 0.6249909972595732 8 Q01813,P51570,P17858,P08237 4 +Mismatched dna binding 0.676069491485521 1.6163567389393374 0.1060172059966335 1.0 0.6249909972595732 5 P54277,P20585 2 +Isopeptidase activity 0.5662842374893015 1.6143707374472422 0.1064470350178017 1.0 0.6249909972595732 9 O95630,Q92905,Q7L5N1 3 +Endodeoxyribonuclease activity producing 5 phosphomonoesters 0.6754723258483023 1.6136349688178788 0.1066066272136501 1.0 0.6249909972595732 5 Q9UQ84,P39748,P27695 3 +Nucleoside triphosphatase regulator activity 0.3595036087316586 1.6134893911378938 0.1066382262625378 1.0 0.6249909972595732 85 P49770,O00410,Q9P2J5,Q8N6T3,P50395,Q14232,P29692,Q9H3U1,Q9Y6D5,O00401,Q96N67,O60343,Q15436,O00429,Q9Y3P9,Q9BTW9,Q92974,P49407,P21359,Q9P258,P80303,Q86X10,P55010,Q13144,P24386,Q15334,Q14185,Q14155,Q9Y2L1,Q9NR50,Q92538,O95373,P43487,Q9H8V3,Q9NVG8,Q8TC07,Q02818,Q9NPQ8,Q01968,Q14C86,Q15042 41 +Translation activator activity 0.7087425469536368 1.6024133100877236 0.1090642434660074 1.0 0.6352061860886715 4 Q7Z478 1 +Trna specific ribonuclease activity 0.6375539461940375 1.5997917608305676 0.1096447872204837 1.0 0.6352061860886715 6 O15091 1 +Dna apurinic or apyrimidinic site endonuclease activity 0.8509458415464204 1.5955815566245652 0.1105822479747189 1.0 0.6352061860886715 3 Q96FZ2 1 +Cyclin dependent protein kinase activity 0.5603505868413275 1.5824793013676497 0.1135401938776943 1.0 0.638477142507675 9 Q00534,Q00535,P11802,O75909 4 +Phosphatidylinositol bisphosphate phosphatase activity 0.6335934422871786 1.5810298263931186 0.1138712181529979 1.0 0.638477142507675 6 Q8NCE2,Q13614,Q96PE3 3 +Lysine acetylated histone binding 0.5347055274130016 1.5736650190904948 0.1155649130126414 1.0 0.6412423580705734 13 Q03164 1 +Map kinase kinase activity 0.5584272298796912 1.57212990959151 0.1159204262796158 1.0 0.6412423580705734 9 P45985,P36507,P52564,Q16539,Q96KB5,P28482 6 +Metalloaminopeptidase activity 0.5330180890740717 1.5645103749966414 0.1176977584066596 1.0 0.6424643323632075 12 P09960,Q9NY33,P55786,P50579,Q9H4A4 5 +Guanyl nucleotide exchange factor activity 0.4508993677820362 1.559145856570704 0.1189618622557719 1.0 0.6452639532472613 40 P49770,Q9Y2L1,Q96N67,Q92538,Q9P258,P80303,Q9H8V3,Q13144,Q14185,Q14232,P29692,Q14155,Q9NPQ8,Q14C86,Q9Y6D5,Q15042 16 +Lys63 specific deubiquitinase activity 0.8390564347566414 1.5497185319446705 0.1212090881422842 1.0 0.6498671879628625 3 O95630,Q01804 2 +Ribonuclease p activity 0.6605775345216701 1.5456122312354792 0.1221982454658747 1.0 0.6526603608407258 5 O15091 1 +Four way junction dna binding 0.6252838576107453 1.5415990272789006 0.1231710620888877 1.0 0.6533766567820543 6 O15347,P09429,P52701 3 +Phosphatidylethanolamine binding 0.6582266314156469 1.5348537643157367 0.1248197528423029 1.0 0.6533766567820543 5 P21359 1 +N methyltransferase activity 0.50829548721575 1.509838492408989 0.1310846404332888 1.0 0.6533766567820543 25 Q86W50,Q03164,Q86TU7,Q7Z4G4 4 +Endoribonuclease activity producing 5 phosphomonoesters 0.5228130175495584 1.5069252547779233 0.131829817221396 1.0 0.6533766567820543 15 Q99575,O75792,O75818,O15091,Q96F86,P39748,Q9UPY3,Q9UQ84,P27695 9 +Protein arginine n methyltransferase activity 0.6869772998805187 1.5064412166744214 0.1319539466875983 1.0 0.6533766567820543 4 O14744,Q99873,O60678 3 +Ubiquitin like protein specific protease activity 0.4608222286607103 1.5055311455110334 0.1321875756673161 1.0 0.6533766567820543 37 Q96K76,Q14694,Q9Y4P1,P51784,O00487,P45974,Q96FW1,Q96RU2,P40818,Q9UPT9,Q6GQQ9,Q7L5N1,Q86UV5,Q92905,Q96BN8,Q9NUQ7,O94966,Q93008,O95630,Q01804 20 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.5203707409234734 1.4910970470062517 0.1359360175215593 1.0 0.6533766567820543 14 Q8N8N7,P49327,Q15392,Q8N4Q0 4 +Cysteine type endopeptidase activity 0.4992967497000669 1.4875953952717598 0.1368576285410596 1.0 0.6533766567820543 27 Q86UV5,P55210,Q14790,Q96K76,P42574,P17655,P55212,Q93008,Q9Y4P1,P51784,Q96RU2,P40818 12 +Mrna methyltransferase activity 0.6128909116252167 1.4826412263045292 0.1381697576861613 1.0 0.6533766567820543 6 Q8N1G2,Q86W50 2 +Map kinase activity 0.6815104512941631 1.4822728632446749 0.1382677058341843 1.0 0.6533766567820543 4 O43318,P28482 2 +Protein serine threonine kinase activator activity 0.5174797640515615 1.4816666677392976 0.1384290103567445 1.0 0.6533766567820543 10 Q13043,P36507,P52564,O75909,P46940,P14635,Q9Y376 7 +Nuclear export signal receptor activity 0.5888143693013946 1.4794552456224437 0.1390186842120164 1.0 0.6533766567820543 7 P55060,Q9HAV4,Q9UIA9 3 +Death receptor binding 0.6807048984468234 1.47870979400114 0.1392178935780834 1.0 0.6533766567820543 4 P42574,Q13546,Q14790 3 +Atp dependent activity acting on dna 0.3129344471243941 1.4728540953652336 0.1407903821923608 1.0 0.6533766567820543 58 P41440,P35251,P25205,Q92900,P18074,Q92614,O14981,Q9HCK8,Q9H4L7,P38935,P46063,Q92499,P13984,Q2NKX8,P33991,P43246,Q13283,O14646,P52701,Q86WJ1,Q9Y620,Q8N3C0,P13010,Q14527 24 +Protein kinase activity 0.3663277120644733 1.4633673433283998 0.1433668895400563 1.0 0.6552571935043889 101 P49761,Q00535,P33981,P53350,Q7Z460,P41240,Q8TD19,P52564,Q16539,Q99570,P27708,Q96KB5,P22392,O75116,Q16512,O96017,Q13546,O15111,O60566,P36507,P11802,O43318,P25440,P67870,Q96SB4,P19784,P78362,Q8IV63,O43683,Q13555,Q13464,Q13043,O14965,Q9Y4B6,P31751,P28482,Q16513,Q14012,Q13535,P45985,Q13153,Q99986,Q9NYV4,Q9UHD2,O75909,Q9H2G2,Q00534,Q13501,P17612 49 +Nucleocytoplasmic carrier activity 0.508493425598315 1.457357669119041 0.145017675586097 1.0 0.6606360776699975 21 O00410,Q92973,Q8TEX9,O00629,O14980,Q9UIA9,P55060,Q9Y5L0,Q96P70,Q9HAV4 10 +Cytokine activity 0.6069666038623296 1.4544013733548091 0.1458350594232906 1.0 0.6621956769904469 6 P43490 1 +1 4 alpha oligoglucan phosphorylase activity 0.8096278548775762 1.4359142516841006 0.1510267426188565 1.0 0.6755659697788396 3 Q13126 1 +Intramolecular oxidoreductase activity interconverting aldoses and ketoses 0.6707642493519511 1.4347071239991334 0.1513705732995642 1.0 0.6755659697788396 4 P34949,P46926 2 +Mismatch repair complex binding 0.6706184839439533 1.4340614640491618 0.1515547236390113 1.0 0.6755659697788396 4 P52701,Q13535 2 +Mutlalpha complex binding 0.6706184839439533 1.4340614640491618 0.1515547236390113 1.0 0.6755659697788396 4 P52701,Q13535 2 +Glucose binding 0.6016276366531726 1.42892510659029 0.1530257604273313 1.0 0.6761233715527674 6 P11413,P06737 2 +D threo aldose 1 dehydrogenase activity 0.6669224230040743 1.4176864033354415 0.1562823414497121 1.0 0.6761233715527674 4 O43488,P48507 2 +Oxidized dna binding 0.5986186427370958 1.4145569659095436 0.1571984338891798 1.0 0.6761233715527674 6 P20585,P52701 2 +Nuclear import signal receptor activity 0.5064380008579132 1.4098435788260375 0.1585858755766498 1.0 0.6761233715527674 14 O00410,Q92973,Q8TEX9,O00629,Q9Y5L0,Q96P70 6 +Sh2 domain binding 0.5046538050421926 1.4089632455006356 0.1588460364815813 1.0 0.6761233715527674 10 Q13501,A1X283,Q96T51 3 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.5049177501237223 1.403833636014279 0.1603683952680938 1.0 0.6761233715527674 16 Q99575,O75792,O75818,O15091,Q96F86,P39748,Q9UPY3,Q9UQ84,P27695 9 +Map kinase scaffold activity 0.6289214221691014 1.4003428381867264 0.1614106785181059 1.0 0.6761233715527674 5 P46940,P36507,Q02750,O60271 4 +Dna insertion or deletion binding 0.661795850161913 1.3949634090186922 0.1630268740269174 1.0 0.6761233715527674 4 P20585,P52701 2 +3 5 exodeoxyribonuclease activity 0.5944054759908138 1.394428084305677 0.163188372235262 1.0 0.6761233715527674 6 P28340,Q07864 2 +Protein disulfide reductase nad p activity 0.5941422594142228 1.3931701528341185 0.1635683431386296 1.0 0.6761233715527674 6 Q9BRA2,Q16881,P00390,P00558,P35754 5 +Fructose binding 0.7984472977007981 1.392611564290022 0.1637372841033482 1.0 0.6761233715527674 3 P08237,P17858 2 +Nad dependent protein deacetylase activity 0.6607316758850525 1.39024527628561 0.1644544090616515 1.0 0.6761233715527674 4 Q96EB6 1 +Actin monomer binding 0.5935185811177787 1.3901893779419887 0.1644713781148969 1.0 0.6761233715527674 6 Q6IBS0,P35080 2 +Proteasome activating activity 0.5920502092050184 1.3831706007313782 0.1666125619319356 1.0 0.6811082443786459 6 P62191,P43686,P62333,P35998,P62195 5 +Deacetylase activity 0.5625406937326026 1.3488841527034552 0.1773741791295322 1.0 0.7038573484160175 7 Q96EB6,Q8IXJ6,Q9NX46 3 +Dopamine receptor binding 0.5838397902574598 1.3439043860533495 0.1789793075327408 1.0 0.7067908065173958 6 Q9Y5X3,P50570,Q15334 3 +Folic acid binding 0.6497609261778059 1.3415863517057431 0.1797301539344848 1.0 0.7077509451544404 4 P41440 1 +Trna cytosine methyltransferase activity 0.7847118542848559 1.3394001213787536 0.1804404499278535 1.0 0.7085464428152899 3 Q8TEA1,Q08J23 2 +Lys48 specific deubiquitinase activity 0.6478494623655843 1.333105958283442 0.1824970343556926 1.0 0.7102562055540217 4 Q93008,Q6GQQ9,O94966 3 +Ubiquitin protein transferase inhibitor activity 0.5350643710419323 1.3234830287718198 0.1856747964563727 1.0 0.7103405386050279 8 Q92990,P62081,P60866 3 +Dynein intermediate chain binding 0.4895855913313001 1.323410635386157 0.1856988568681696 1.0 0.7103405386050279 10 P63172,P42858,Q14204,P43034 4 +Nadplus adp ribosyltransferase activity 0.5793724198410687 1.3225277248028058 0.185992483463695 1.0 0.7103405386050279 6 Q96EB6,Q8IXJ6,Q9UGN5,P09874 4 +Glutathione disulfide oxidoreductase activity 0.7801536302824543 1.3217435287175292 0.1862535685764306 1.0 0.7103405386050279 3 P35754 1 +Tbp class protein binding 0.5113160136681023 1.3173294465298058 0.1877282189184466 1.0 0.7103405386050279 9 Q86VP6,P62191,P62195,O14981 4 +Tau protein kinase activity 0.5561258519230236 1.316946928651507 0.187856414559409 1.0 0.7103405386050279 7 O75116 1 +H4 histone acetyltransferase activity 0.7776534019077346 1.312060021942509 0.1894998834856598 1.0 0.7103405386050279 3 Q9UPT9 1 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.6426600603272609 1.310081320071053 0.1901683270025398 1.0 0.7107095116395188 4 Q8NCE2,Q13614 2 +Catalytic activity acting on dna 0.3419476130610688 1.3033393973377674 0.1924589163988157 1.0 0.7170631063161013 92 P41440,P25205,Q9C0B1,P18074,Q92614,Q9UQ84,O14981,Q9H4L7,P38935,P46063,Q92499,P26358,P39748,P29372,P18858,P28340,Q66K74,O14646,P52701,Q86WJ1,Q9NUW8,P15531,Q07864,Q9Y620,Q8N3C0,Q96FZ2,Q14527,P27695 28 +Phosphofructokinase activity 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.7170631063161013 3 P17858,P08237 2 +Fructose 6 phosphate binding 0.7739623768288929 1.2977667876500976 0.1943674855744994 1.0 0.7170631063161013 3 P17858,P08237 2 +Retromer complex binding 0.6393307590742948 1.2953096979850836 0.19521341503548 1.0 0.7170631063161013 4 P20645 1 +Modification dependent protein binding 0.3024528944583736 1.2945684573453469 0.1954691394548913 1.0 0.7170631063161013 61 Q03164,P42695,Q14997,P46379,Q04323,Q9UER7,Q96S82,Q7Z4V5,P52701,Q13501,Q06787 11 +Protein kinase a regulatory subunit binding 0.4839691955000159 1.2915106792922004 0.1965266544084309 1.0 0.7176191575826529 10 Q9Y6D5 1 +Phosphatase activity 0.3021745274618888 1.2911539489177513 0.1966502999975419 1.0 0.7176191575826529 61 Q08623,Q8NCE2,Q99956,Q9NPH0,Q8TF05,Q96PE3,Q99504,O60942,Q5TFE4,Q08209,O15357,Q15257,P30307,Q06124,Q9H993,Q9H0R4,Q9H2U2,Q14738,Q13614 19 +Nedd8 specific protease activity 0.7672626063667721 1.271831651356092 0.2034329405107042 1.0 0.7348874020110884 3 Q92905 1 +Ubiquitin conjugating enzyme binding 0.6005720194009594 1.2698092235917395 0.2041525944037199 1.0 0.7348874020110884 5 O95376,O75150 2 +Cytoskeletal anchor activity 0.5459210323616799 1.2661278212832667 0.2054673235148651 1.0 0.7348874020110884 7 Q9UQB8 1 +Nucleoside kinase activity 0.6305256869772862 1.256249868345669 0.2090253914939852 1.0 0.735811605410645 4 Q9BZX2,P30085,P04183 3 +14 3 3 protein binding 0.6267924904394656 1.2396951719708766 0.2150881635924979 1.0 0.7458529851938859 4 P85037 1 +General transcription initiation factor activity 0.5177415408943971 1.2335659071257146 0.2173647035903221 1.0 0.7479011658695653 8 Q92759,P35269 2 +Exodeoxyribonuclease activity 0.4719831798240164 1.2234656098771202 0.2211538856541648 1.0 0.7519232112241604 10 P28340,Q9UQ84,Q07864 3 +Pyrimidine nucleotide binding 0.5885553204030444 1.2144811416276762 0.2245640468873655 1.0 0.7579716255713984 5 P08238,Q16851,Q9H773 3 +Peptidase activity 0.3655938777700607 1.1935999539891082 0.2326344920019969 1.0 0.7776798125918075 121 Q16740,P55210,P60900,Q96K76,P17655,Q9Y4P1,P51784,P48147,P09960,Q9NY33,P49720,Q96FW1,Q96RU2,Q9H4A4,P28070,P49721,P40818,Q4J6C6,O43847,Q9UPT9,Q14790,Q86TI2,P55212,P55786,Q7L5N1,Q86UV5,Q92905,Q96BN8,Q9NUQ7,P42574,P28074,P52888,Q96FZ2,O95630,P50579,Q01804 36 +Dna polymerase activity 0.4876698871678932 1.189156163526934 0.2343782209137879 1.0 0.7816345453440677 9 P28340 1 +O methyltransferase activity 0.508132457500621 1.183736068778381 0.2365175563771324 1.0 0.7849504623865319 8 Q8N1G2,O60725,Q9H993,Q7L2J0 4 +Serine hydrolase activity 0.4661004633597119 1.182145459501498 0.237147989247046 1.0 0.7849504623865319 19 Q16740,P48147 2 +Inositol phosphate phosphatase activity 0.6135317043211788 1.1809442052222094 0.2376248889003704 1.0 0.7849504623865319 4 Q96PE3 1 +Gamma tubulin binding 0.5029403506029719 1.1568430542867858 0.2473364879520629 1.0 0.8036994503617152 8 Q16512,Q14155 2 +Peptidase activator activity 0.4599589985814855 1.1494924153562671 0.2503529924689205 1.0 0.8062895137906739 11 P61289,Q14997,O00487 3 +Ww domain binding 0.5416535631698014 1.1420854420302902 0.2534185060721983 1.0 0.8094531217247413 6 P30307,Q96Q89 2 +Gdp dissociation inhibitor activity 0.4997165444701406 1.1401600613464726 0.254219623158717 1.0 0.8094531217247413 8 P55010,P24386,P43487 3 +Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity 0.7315677048292409 1.1340522736464465 0.256772621564433 1.0 0.8101518182890385 3 Q8NCE2 1 +Protein deacetylase activity 0.5692407028807036 1.1257203140357428 0.2602839224972735 1.0 0.8101518182890385 5 Q96EB6 1 +Tpr domain binding 0.6004674912043857 1.1231935604210856 0.2613552969274542 1.0 0.8101518182890385 4 P07900,O76094 2 +Metal dependent deubiquitinase activity 0.5166805099775181 1.120725086134833 0.2624049005740017 1.0 0.8101518182890385 7 Q92905,Q7L5N1 2 +Phosphoric ester hydrolase activity 0.3032018875590397 1.119694816326299 0.2628438347618989 1.0 0.8101518182890385 73 Q08623,Q8NCE2,Q9Y3Z3,Q99956,Q9NPH0,Q8TF05,Q96PE3,P19174,Q99504,O60942,Q5TFE4,Q08209,O15357,Q15257,P30307,Q06124,Q9H993,Q9H0R4,Q9H2U2,Q9NUW8,Q14738,Q13614,P27695 23 +Deaminase activity 0.5363529960590584 1.116792447056837 0.2640830790122224 1.0 0.8108630223414934 6 P00813 1 +Phosphatidylinositol phosphate phosphatase activity 0.4948205857635541 1.1148502018831736 0.2649146194757232 1.0 0.8116202345410019 8 Q8NCE2,Q96PE3,O15357 3 +Phosphatidylinositol 4 5 bisphosphate binding 0.4531817279680202 1.1109589803037812 0.2665860061444591 1.0 0.8131748196178907 11 Q9BPX3,Q13045,Q6IBS0,P35080,P07737,Q8TEW0 6 +Adenylyltransferase activity 0.4921755284471084 1.1011915931158582 0.2708132798177742 1.0 0.8147679916176173 8 Q96Q11,O43252,Q8NFF5,P51003,Q13057 5 +Protein carboxyl o methyltransferase activity 0.7223386698353729 1.0986049767669028 0.2719404059866073 1.0 0.8147679916176173 3 Q9H993 1 +Oxidoreductase activity acting on the ch ch group of donors 0.4295401150527325 1.097514000516874 0.2724167639301482 1.0 0.8147679916176173 31 P11310,Q15392,Q8N4Q0 3 +D1 dopamine receptor binding 0.7220065691251181 1.097331275157977 0.2724966039339103 1.0 0.8147679916176173 3 Q9Y5X3,Q15334 2 +Aldehyde lyase activity 0.5617466550480669 1.091379521428508 0.2751059196017282 1.0 0.8147679916176173 5 Q9H993,P09972 2 +Amidine lyase activity 0.5902031063321268 1.0779543245987575 0.2810541401516802 1.0 0.8185174451700387 4 O75592,Q8WUX2,P30566 3 +Ribose phosphate diphosphokinase activity 0.7148402508211387 1.069881056563748 0.2846728509229554 1.0 0.8185174451700387 3 P11908,O60256 2 +Diphosphotransferase activity 0.7148402508211387 1.069881056563748 0.2846728509229554 1.0 0.8185174451700387 3 P11908,O60256 2 +Heparin binding 0.4423793138463054 1.044451678233572 0.2962764647229221 1.0 0.8428763098443948 12 P51858,P20248,O14737,P43034 4 +Aminoacyl trna editing activity 0.4385725064339963 1.0347813948413522 0.3007710136188564 1.0 0.8458717936233497 10 P41252,P26640,Q9P2J5 3 +Epidermal growth factor receptor binding 0.5479533910965154 1.0283901077583355 0.3037663599010365 1.0 0.8469006114040898 5 P62993,P18085,Q92600,O60749 4 +Gtpase binding 0.325669017565483 1.0217612957279465 0.3068938920738593 1.0 0.84793644308157 99 O00410,Q8TEX9,P50395,Q96KP1,P46940,Q92696,P61970,O75116,P50748,Q16512,Q7L576,Q96N67,O14980,Q9P2R3,O00429,Q9Y3P9,Q9UI26,P07814,Q96S59,P41252,Q92974,O15397,Q92973,Q13464,Q9P258,Q9Y2T2,Q9UIA9,P24386,P55060,Q9Y5L0,Q96P70,Q5VSL9,Q9HAV4,Q16513,P07737,Q9H4M9,O95373,P43487,Q13153,P07900,O60610,Q9H8V3,Q9NVG8,Q8TD16,Q9UJY4,Q01968,P67809,Q14C86,Q15042 49 +Translation initiation factor binding 0.4398351656294719 1.021206282642405 0.3071567163804456 1.0 0.84793644308157 18 Q6PKG0,P06730,P62847,Q13144,Q04637,Q06787 6 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines 0.4909358929376665 0.9936055864935672 0.3204149233592561 1.0 0.862788323593483 7 P00813,Q01433 2 +Flap endonuclease activity 0.6936467772406634 0.9891589442813696 0.3225853819718947 1.0 0.862788323593483 3 Q9UQ84 1 +Dynein heavy chain binding 0.5678016726403674 0.9798286651907756 0.3271706998696704 1.0 0.862788323593483 4 O43237,Q96EX3,Q9Y6G9 3 +Racemase and epimerase activity 0.5363706459818025 0.9757797218492904 0.3291736357426336 1.0 0.862788323593483 5 Q8NCW5,Q96C23,Q13630 3 +Peptide alpha n acetyltransferase activity 0.6885637503732297 0.9699199268205546 0.3320864065781739 1.0 0.863672482779803 3 Q9BXJ9,Q14CX7 2 +Gtpase activator activity 0.3620945390976378 0.9661100952947512 0.3339890934831084 1.0 0.8637660737868724 43 Q9P2J5,Q8N6T3,P50395,Q9H3U1,O60343,Q15436,O00429,Q9Y3P9,Q9BTW9,P49407,P21359,Q86X10,P24386,Q14185,Q15334,P43487,Q14C86,Q9NVG8,Q9H8V3,Q01968,Q8TC07,Q15042 22 +Protein kinase a catalytic subunit binding 0.5043631757211458 0.9650691102823842 0.3345101975023936 1.0 0.8637660737868724 6 P41240 1 +Protein arginine omega n asymmetric methyltransferase activity 0.6867721707972418 0.9631516703807512 0.335471414709017 1.0 0.8637660737868724 3 Q99873,O60678 2 +Histone arginine n methyltransferase activity 0.6867721707972346 0.9631516703807228 0.3354714147090312 1.0 0.8637660737868724 3 O14744,Q99873 2 +Rna strand annealing activity 0.5334175379684566 0.962416993599258 0.3358401807693578 1.0 0.8637660737868724 5 Q06787,P51114 2 +Endodeoxyribonuclease activity 0.4241195752251474 0.9541008948784738 0.3400325731748466 1.0 0.8699321925182821 10 Q9UQ84,P39748,P27695 3 +Phosphatidylinositol 3 phosphate binding 0.5012999579779376 0.950658337294215 0.3417778441213626 1.0 0.8710024034829605 6 O60493,A1X283,Q8TEW0 3 +Structural constituent of synapse 0.5297730342234339 0.9459576485010172 0.3441701879806909 1.0 0.8737098695043789 5 O15020,Q15334 2 +Ligase activity forming carbon oxygen bonds 0.3969500699155447 0.9383252746160744 0.3480772747709884 1.0 0.8789975470797117 34 Q9P2J5,Q9BTE6,Q96I59,P26639,O43776,P26640,P49591,P07814,P41250,P47897,P49589,P41252,P23381,P54136,P54577,Q9Y285,Q9NSD9 17 +Dipeptidase activity 0.5579706993807729 0.9371168535742714 0.3486984530380779 1.0 0.8789975470797117 4 Q96KP4,Q8IYS1 2 +Fibroblast growth factor binding 0.5268389056027004 0.9327336972691946 0.3509574818545817 1.0 0.8830951799734422 5 P39019 1 +Omega peptidase activity 0.4045472227390158 0.9273630041123344 0.353738092325532 1.0 0.8859583676584872 31 Q86UV5,Q9UPT9,O94966,Q96K76,Q96BN8,Q6GQQ9,Q14694,Q93008,P45974,Q96FW1,P51784,Q96RU2,O95630,Q01804,O00487,P40818 16 +Histone threonine kinase activity 0.5540314080926048 0.9200764684490984 0.3575328003179185 1.0 0.891107308063583 4 Q99986,Q16512 2 +Phosphatase inhibitor activity 0.4756224179142445 0.9187687935216948 0.3582165183670924 1.0 0.891107308063583 7 Q01105,Q9Y570 2 +Deoxyribonuclease activity 0.4211996743142608 0.9116375027239546 0.3619595734971295 1.0 0.8978143157562252 18 P28340,P15531,Q07864,Q9UQ84,P27695 5 +Calcium dependent protein serine threonine phosphatase activity 0.6719493655676256 0.9074361962423408 0.3641761755666275 1.0 0.9001603787962725 3 Q08209 1 +Alpha tubulin binding 0.472942191955991 0.905751653920302 0.3650673155655344 1.0 0.9001603787962725 7 Q9HC35,Q9P265 2 +Nucleotide diphosphatase activity 0.6712451478053174 0.9048027221341014 0.3655699093023017 1.0 0.9001603787962725 3 Q9BW91,Q9BY32 2 +Dynein light intermediate chain binding 0.5190680151635645 0.8978384176287088 0.3692716998334775 1.0 0.9046832154092576 5 Q8TD16 1 +Dna helicase activity 0.3641318179019136 0.868544797648682 0.3850961594203355 1.0 0.9077207315467324 40 P33992,P25205,Q92900,Q12873,P18074,Q9HCK8,Q9H4L7,P38935,P46063,P13984,Q2NKX8,P33991,P49736,Q13283,O14646,Q86WJ1,Q9Y620,Q8N3C0,P13010 19 +Alditol nadpplus 1 oxidoreductase activity 0.6612356303754385 0.8675187937532973 0.3856578189570512 1.0 0.9077207315467324 3 O43488 1 +Kinase regulator activity 0.2970120043294335 0.8613130000490201 0.3890656776489107 1.0 0.9077207315467324 52 P31946,Q13177,P52564,O95067,P42771,P46940,Q02750,Q9UER7,Q9Y376,Q9H9T3,P36507,P11802,P47897,P08238,P67870,Q9UHD1,P49736,Q13043,P60983,P20248,Q92616,Q16543,Q9P287,O75909,A4D1P6,P23381,P42574,P14635 28 +Sulfurtransferase activity 0.4818469492344693 0.8598414187718674 0.3898764642246544 1.0 0.9077207315467324 6 Q2VPK5 1 +Phosphatase binding 0.2827060534543232 0.8551109594520033 0.3924897229561268 1.0 0.9077207315467324 54 Q8IV63,Q5H9R7,Q9Y2V2,Q15257,Q9UHD2,P41240,Q9Y570,O00203,Q16539,Q15334,Q9UJX4,P35269,O60493,Q92796,P28482,P40763,Q9UPR3,P78318 18 +Peptide hormone receptor binding 0.6578083009853659 0.8548195077942036 0.3926510768455378 1.0 0.9077207315467324 3 P62195,Q06124 2 +Hormone receptor binding 0.6578083009853659 0.8548195077942036 0.3926510768455378 1.0 0.9077207315467324 3 P62195,Q06124 2 +Single stranded dna binding 0.262815666191939 0.8502637097363589 0.3951784880358655 1.0 0.9090409444257368 59 P53999,Q9BUI4,P35244,P38935,Q9NUW8,P25205,Q9Y3Z3,P46063,P20585,P09429,Q96FZ2,P67809 12 +Armadillo repeat domain binding 0.6548223350253797 0.8437852978371985 0.3987893925586152 1.0 0.9131547383730964 3 A5YKK6,Q9HCK8 2 +Kinase activator activity 0.4078624127235377 0.8346353537832053 0.4039230501978013 1.0 0.9166873975468434 17 Q13043,Q13177,P36507,P52564,O75909,P46940,Q9UER7,P14635,Q9Y376 9 +Inositol trisphosphate phosphatase activity 0.6515686800863452 0.8317945387388995 0.4055249270423646 1.0 0.9166873975468434 3 Q96PE3 1 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.6515686800863452 0.8317945387388995 0.4055249270423646 1.0 0.9166873975468434 3 Q96PE3 1 +L ascorbic acid binding 0.4203392424833637 0.8302566436697749 0.4063936956125891 1.0 0.9166873975468434 9 Q9GZT9,Q32P28,P13674 3 +Protein phosphatase 1 binding 0.5326097471175469 0.8283119887540509 0.4074938350133048 1.0 0.9176840161688964 4 P62136,Q9UQ13 2 +Growth factor binding 0.4013092027754857 0.821379731900608 0.4114300046820598 1.0 0.9250539137528894 11 O43847,P20248,P39019,P27695 4 +Nucleotidyltransferase activity 0.2982831138734917 0.8103982018503745 0.417711351001155 1.0 0.928213020852208 51 P28340,Q9BUI4,O14802,Q9NR45,Q9BWH6,Q9UKK9,Q07864,Q5TAX3,Q2VPK5,O60942,P51003,Q96IJ6,Q13057,P49642 14 +Phosphatidylinositol phosphate 5 phosphatase activity 0.6422933018099973 0.7978098957796449 0.4249808178026886 1.0 0.928213020852208 3 O15357 1 +Phosphatidylinositol trisphosphate phosphatase activity 0.6422933018099973 0.7978098957796449 0.4249808178026886 1.0 0.928213020852208 3 O15357 1 +Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity 0.6422933018099973 0.7978098957796449 0.4249808178026886 1.0 0.928213020852208 3 O15357 1 +Scaffold protein binding 0.3994038285375469 0.7956291981778243 0.4262475903735747 1.0 0.928213020852208 22 Q14790,Q9UQB8,P36507,O43318,Q9Y4P1,Q8IWS0 6 +Cytokine receptor binding 0.3970154127545363 0.7930319588578095 0.4277592030681607 1.0 0.928213020852208 24 O00560,P62993,Q9NXR7,Q14790,P42574,P19174,O43776,Q9Y5K6,Q9UKL3,P30046,Q96AC1,Q13546,P54577 13 +Nuclear receptor activity 0.8641791044776126 0.7912655970125125 0.4287890196724941 1.0 0.928213020852208 2 P40763 1 +Racemase and epimerase activity acting on carbohydrates and derivatives 0.6404896984174488 0.7912374388281244 0.4288054480014402 1.0 0.928213020852208 3 Q96C23,Q13630 2 +Lipopolysaccharide binding 0.4661793691629323 0.7878005822088419 0.430813360467273 1.0 0.928213020852208 6 Q8WTV0,P28070 2 +Intramolecular transferase activity phosphotransferases 0.4925495638753833 0.7804773674466039 0.4351099442060433 1.0 0.933143480343422 5 O95394,P18669 2 +Uridylyltransferase activity 0.6363093460734459 0.7760513476678247 0.4377186685135514 1.0 0.9364291209909976 3 Q5TAX3,Q16222 2 +Damaged dna binding 0.3880500267239361 0.7755994928568763 0.4379854999183146 1.0 0.9364291209909976 28 P28340,P35244,P18074,P20585,P09429,P29372,P27695 7 +Histone serine kinase activity 0.5185325363964333 0.7690140646521318 0.4418849611515885 1.0 0.9418771190295326 4 Q99986 1 +Calmodulin dependent protein kinase activity 0.6337268230496997 0.7667038374928866 0.4432576215161066 1.0 0.9433604952571796 3 Q13555 1 +Single stranded dna exodeoxyribonuclease activity 0.4876734827159474 0.7592498561636359 0.4477031072604907 1.0 0.9447883987664284 5 Q9UQ84 1 +Tumor necrosis factor receptor superfamily binding 0.4223448007926862 0.7486834842296993 0.4540480004619693 1.0 0.952099326397568 8 P42574,Q13546,Q9NXR7,Q14790 4 +Pentosyltransferase activity 0.3920886842196185 0.7453196415578747 0.45607850995696 1.0 0.952099326397568 18 Q96EB6,P00491,P11172,Q06203,Q8IXJ6,P00492,Q13126,P07741,P43490 9 +Cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.8498507462686593 0.7452863428774651 0.4560986354664869 1.0 0.952099326397568 2 Q14790 1 +Translation elongation factor activity 0.3894728307512335 0.7450479737640255 0.4562427188189206 1.0 0.952099326397568 13 Q05639,Q9Y450,P63241,Q7Z2Z2,P29692,P13639,P26641 7 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.6269852981221801 0.7424312313493832 0.457826102951564 1.0 0.9539754671367418 3 P42771 1 +Kinase activity 0.3542425239319273 0.7393404629493364 0.4597002849218381 1.0 0.95645104056872 152 P49761,Q00535,P33981,P53350,Q7Z460,P41240,Q8TD19,Q16539,Q99570,P27708,Q96KB5,P22392,O75116,Q16512,O96017,O15111,Q13572,O60566,P08237,P14618,P36507,P11802,P17858,O43318,P11908,P25440,P67870,Q969G6,Q96SB4,O00443,P49903,P19784,P78362,Q8IV63,O43683,Q13555,Q15126,Q13464,Q13043,O14965,Q9Y4B6,P31751,Q8TBX8,P04183,Q13057,P28482,P17612,Q16513,Q14012,Q13535,Q9UJ70,P51570,Q9Y4A5,P45985,Q9BZX2,Q13153,Q99986,Q9NYV4,P15531,P00568,P35790,Q9UHD2,O75909,O00764,Q00534,Q9H2G2,Q9NVE7,Q13501,P12277,Q01813,P42356,P30085,Q00013 73 +G protein alpha subunit binding 0.5089098102996051 0.7290396504167354 0.4659774086374408 1.0 0.9651894615759176 4 P80303,Q9NPQ8 2 +Endoribonuclease activity 0.3866528584736975 0.7260600956629149 0.4678019304683731 1.0 0.9657878719019698 23 Q99575,Q96F86,O15091,O75818,O75792,P39748,Q9UPY3,Q9UQ84,P27695 9 +Magnesium ion binding 0.2730979728514834 0.7240829087205922 0.4690148367032145 1.0 0.9657878719019698 77 Q9NX46,P53350,Q7Z460,Q96DE0,O95394,O60256,Q15181,Q13572,O75874,P30520,P14618,P00492,Q9UBT2,P33316,P48735,P48506,O43318,P11908,Q15382,P39748,Q969T7,Q96SB4,P49642,Q14558,Q9NRN7,P78362,Q9NSD9,Q13043,P43246,P36871,P51003,P52701,Q9H2U2,P15531,Q9UKK9,O00764,P17612 37 +Heat shock protein binding 0.2620482952459377 0.7117567359517227 0.4766154277456387 1.0 0.9657878719019698 55 Q9UNN5,Q00535,P68400,P54652,Q9UER7,Q99615,Q9H3U1,P46379,O75937,P08238,P31689,Q9UHD1,Q8WXX5,Q99543,P0DMV9,P11142,P31948,Q08752,P06493,Q16543,Q15185,O95801,O94966,Q14974,Q6W2J9,Q9Y4R8,Q15785,P42858,O60884,O95433,Q0VDF9,P53602 32 +Rna stem loop binding 0.3965110559493099 0.7086484580286001 0.4785426571578257 1.0 0.9657878719019698 9 Q86W50,Q06787,O75534 3 +Peptide n acetyltransferase activity 0.3811498872605461 0.7065078459510241 0.4798723752209255 1.0 0.9657878719019698 12 O14929,Q9UPT9,Q14CX7 3 +Polyubiquitin modification dependent protein binding 0.3849688125289175 0.7058311173969865 0.480293168297264 1.0 0.9657878719019698 19 Q9NRR5,Q6GQQ9,Q04323,P46379,P55036,Q96S82,Q13501,Q8TAT6 8 +Rna 7 methylguanosine cap binding 0.4134538486836981 0.70568499077347 0.4803840569318809 1.0 0.9657878719019698 8 Q6PKG0,Q96C86,P06730,Q8TEQ6,O60573 5 +Double stranded telomeric dna binding 0.4475877912962482 0.7040073016163311 0.4814282264900171 1.0 0.9657878719019698 6 Q15554,P13010,P27695 3 +Flavin adenine dinucleotide binding 0.3709387792778085 0.6942379456479022 0.4875329995710635 1.0 0.9672237780470804 30 P11310 1 +Dna binding transcription repressor activity 0.375991623680755 0.6863452187039311 0.4924954405362445 1.0 0.9672237780470804 11 P10589,P85037 2 +Pdz domain binding 0.3795907241290311 0.6799739056834972 0.4965209836048019 1.0 0.9680423092938376 16 P36507,Q9UQB8 2 +Protein arginine omega n monomethyltransferase activity 0.8226865671641794 0.66031116431389 0.5090541671180515 1.0 0.9804150024283051 2 Q99873 1 +Ephrin receptor binding 0.463496368204852 0.6560732498379335 0.5117769950248625 1.0 0.9806985165115244 5 P62993,Q00535,P22681 3 +Mitogen activated protein kinase binding 0.4365997290803141 0.6555494925967079 0.5121140320059181 1.0 0.9806985165115244 6 Q96EB6,Q99873 2 +Nucleoside diphosphate kinase activity 0.4364749642653758 0.6550044368763563 0.512464897421536 1.0 0.9806985165115244 6 P15531,P00568,P22392 3 +Protein adp ribosylase activity 0.6001791579575952 0.6479895243171794 0.5169917258043286 1.0 0.9868451484211148 3 Q9UGN5,P09874 2 +K48 linked polyubiquitin modification dependent protein binding 0.4344379490404053 0.6461227062051568 0.5181998914234263 1.0 0.9868451484211148 6 Q9NRR5,Q8TAT6,Q04323 3 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.3828573354202365 0.6411918513893601 0.5213980431944163 1.0 0.9888828193374372 9 Q96AC1,Q7Z3T8,Q92538 3 +Polynucleotide adenylyltransferase activity 0.5968945954016249 0.6366728977045493 0.5243379307540659 1.0 0.9931014168485752 3 P51003,Q96Q11 2 +Histone kinase activity 0.3817044335549077 0.6355846725791303 0.52504716227934 1.0 0.9931014168485752 9 Q99986,O14965,Q16512 3 +C3hc4 type ring finger domain binding 0.5933114362496352 0.6243976215332606 0.5323664867077516 1.0 1.0 3 P31689,P0DMV9 2 +Oxidative rna demethylase activity 0.8050746268656763 0.6069848817139951 0.5438609452817147 1.0 1.0 2 Q6P6C2 1 +G quadruplex rna binding 0.5862306908332414 0.6003641231817904 0.5482635924067554 1.0 1.0 3 Q06787 1 +Microtubule motor activity 0.3649080062591752 0.5981955824150437 0.5497094387205859 1.0 1.0 18 Q99661,Q15058,Q96Q89,Q14204,P52732,O60333 6 +Oxidoreductase activity acting on ch or ch2 groups 0.8008955223880638 0.594558671233756 0.5521385129236807 1.0 1.0 2 P23921 1 +Rna cap binding 0.3577843698900005 0.5863592070400258 0.5576341512893794 1.0 1.0 12 Q6PKG0,Q96C86,P06730,Q8TEQ6,O43432,O60573,O15371 7 +N acyltransferase activity 0.3591901270497278 0.5674990350548746 0.5703751819990674 1.0 1.0 19 O14929,Q9UPT9,Q14CX7,P27544 4 +Metallopeptidase activity 0.3181869958210136 0.5640990883453796 0.5726866984666197 1.0 1.0 41 O43847,Q92905,P09960,Q9NY33,O95630,P55786,P52888,P14735,P50579,Q9H4A4,O00487,Q7L5N1 12 +Dna translocase activity 0.7904477611940333 0.5639016995126019 0.572821033372287 1.0 1.0 2 Q9Y620 1 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.3658610808104133 0.5601296592422612 0.5753910014319226 1.0 1.0 9 Q00534,P28482,P11802,O75909 4 +Mirna binding 0.3535147679148718 0.5448981351500123 0.5858235789302031 1.0 1.0 16 Q5TAX3,P67809,Q8IWR0 3 +3 5 dna helicase activity 0.362530338380884 0.5446791166919727 0.5859742301454198 1.0 1.0 9 P33992,P49736,P46063,Q8N3C0,P33993 5 +Poly g binding 0.4085868511301163 0.5365779364359413 0.5915591879193887 1.0 1.0 6 Q86TB9 1 +Ribonuclease p rna binding 0.4593247975974601 0.5327325461559208 0.5942187332900284 1.0 1.0 4 O75818 1 +Microtubule minus end binding 0.4059070894105631 0.5255992002283759 0.5991667125309768 1.0 1.0 6 Q9BSJ2 1 +Endonuclease activity 0.328285978380331 0.5228444655932072 0.6010824933344368 1.0 1.0 36 Q9Y2L1,Q9UQ84,O15091,O75818,O94919,Q96F86 6 +Structural constituent of postsynapse 0.5606247949903751 0.5161934664970819 0.6057192930278672 1.0 1.0 3 Q15334 1 +Gtp dependent protein binding 0.4034066873400646 0.5154263835052803 0.6062550998494647 1.0 1.0 6 O00203,P60953,P61020,O00429 4 +Metalloendopeptidase activity 0.3456445819020441 0.5150140828831266 0.6065431790506661 1.0 1.0 14 O43847,P52888,Q92905 3 +Phosphatidylinositol phosphate binding 0.3404423867866648 0.5145956064916603 0.606835635891771 1.0 1.0 30 O00560,Q92538,Q9BPX3,Q96AC1,Q13045,Q9Y4P8,Q7Z3T8,P22059,Q6IBS0,P46940,Q9Y5X3,O60493,A1X283,P35080,Q9BTX7,P07737,Q8TEW0 17 +Atp dependent activity acting on rna 0.2538709416305578 0.5144821823767398 0.6069149144363861 1.0 1.0 53 Q7Z478,Q9NUL7,Q14240,Q6P158,P38935,P26196,Q8IX18,Q92499,Q9Y620,Q15477,O60231,Q9H6S0,Q7L014 13 +Protein serine threonine phosphatase activity 0.3465111142410463 0.5039906142899654 0.6142679725078344 1.0 1.0 22 O00743,P60510,Q9H2U2,Q8NCE2,Q99956,Q9UNI6,P51452,O15355,Q08209 9 +Mitogen activated protein kinase p38 binding 0.7668656716417928 0.4970210881523893 0.6191741803672159 1.0 1.0 2 Q99873 1 +Protein prenyltransferase activity 0.7659701492537332 0.4945489162067076 0.6209185690436709 1.0 1.0 2 P24386 1 +Protein geranylgeranyltransferase activity 0.7659701492537332 0.4945489162067076 0.6209185690436709 1.0 1.0 2 P24386 1 +Hsp70 protein binding 0.3440005107386827 0.4927120068694713 0.6222160925805207 1.0 1.0 18 O60884,O75937,P31689,P46379 4 +Co smad binding 0.762089552238808 0.4838963126303078 0.6284594574215623 1.0 1.0 2 Q93008 1 +Protein kinase a binding 0.3413750800993592 0.4774976406529509 0.6330078005052588 1.0 1.0 20 Q99996,Q9Y6D5 2 +Actinin binding 0.4176420206366109 0.4732176502233847 0.6360579066285421 1.0 1.0 5 Q04206,Q96HC4 2 +Helicase activity 0.2690666864584139 0.4689275644093825 0.6391214128560336 1.0 1.0 97 P25205,P18074,Q9H6S0,O14981,Q7Z478,Q9H4L7,P38935,Q6P158,P26196,P42694,P46063,Q92499,Q92620,O60231,Q9NUL7,Q8IX18,Q14240,Q7L014,Q7Z7L1,Q86WJ1,Q9Y620,Q15477,Q14527 23 +Ribosome binding 0.3031603131846647 0.4655833167149744 0.64151378696398 1.0 1.0 41 Q9BY44,Q9NTK5,P38935,P62495,P46379,Q8TEQ6,Q92616,P63241,O76094,Q9BXJ9,O60678,P13639,Q06787,P60059 14 +Map kinase phosphatase activity 0.7549253731343339 0.4644920940037562 0.6422952225123038 1.0 1.0 2 Q99956 1 +Protein phosphatase binding 0.2913116859416664 0.4625264167813595 0.6437038628426326 1.0 1.0 44 Q8IV63,Q5H9R7,Q15257,Q9UHD2,P41240,Q9Y570,O00203,Q16539,Q15334,Q9UJX4,P35269,O60493,P40763,Q9UPR3,P78318 15 +Phosphatidylinositol binding 0.2476019024662663 0.4615594472183217 0.6443972814032959 1.0 1.0 53 O00560,Q53T59,Q9H6U6,Q6IBS0,P46940,Q9BTX7,Q8WTV0,Q9P2R3,P22059,Q00169,Q96AC1,O00443,Q8TEW0,Q13045,Q9Y4P8,O60493,A1X283,Q9Y490,Q15036,Q92538,Q7Z3T8,Q9Y5X3,Q9UJY4,P35080,P07737,Q9BPX3 26 +Arp2 3 complex binding 0.3887408387854821 0.4572349455950328 0.6475021830611243 1.0 1.0 6 Q9NZQ3,P60983,Q13576,Q9BR76 4 +Nedd8 transferase activity 0.7501492537313454 0.4517499830146531 0.6514491058094238 1.0 1.0 2 P61081 1 +Receptor tyrosine kinase binding 0.3344436873187579 0.4499195940177221 0.6527684186737819 1.0 1.0 17 P22681,O43318,Q13501,Q06124 4 +Peptide lysine n acetyltransferase activity 0.325229246140983 0.4475701479218593 0.6544634514549181 1.0 1.0 10 Q9UPT9 1 +Chemokine receptor binding 0.4103838587739078 0.4462724385285595 0.6554004626726866 1.0 1.0 5 O43776 1 +Protein tyrosine phosphatase activity 0.3332875191155338 0.444580493606473 0.6566229467188414 1.0 1.0 17 Q8NCE2,Q99504,Q99956,P30307,O60942,Q06124,Q13614 7 +1 phosphatidylinositol binding 0.3853404534102058 0.4441272251642252 0.6569506039391932 1.0 1.0 6 Q7Z3T8 1 +Phosphoprotein phosphatase activity 0.3062212412385456 0.4436535462706119 0.6572930858890198 1.0 1.0 39 Q8TF05,Q9H2U2,Q15257,Q8NCE2,Q99504,Q99956,Q14738,O60942,P30307,Q06124,Q08209,Q13614 12 +Ubiquitination like modification dependent protein binding 0.4095535950543169 0.4432309581687241 0.6575986886451761 1.0 1.0 5 Q9UER7 1 +Nuclease activity 0.238663284994076 0.4422210772061811 0.6583292353713877 1.0 1.0 72 Q9Y3Z3,O15091,Q6L8Q7,Q9UQ84,Q96F86,Q92499,O75818,P39748,P28340,Q66K74,Q9HB07,Q9UIV1,Q13283,O94919,Q9UPY3,Q9Y2L1,Q96C86,Q9NUW8,P15531,Q07864,Q99575,O75792,A5YKK6,P27695 24 +Protein tyrosine kinase activity 0.3294648495119777 0.434775136020083 0.6637256542524357 1.0 1.0 15 P49761,P45985,P33981,P36507,P41240,P52564,Q96KB5 7 +Phosphatidylinositol 4 phosphate binding 0.3820551183903469 0.4316095225583432 0.6660252362694217 1.0 1.0 6 Q9Y5X3,O60493 2 +Peptidyl proline dioxygenase activity 0.3811749512972817 0.4282809304630739 0.6684466008136787 1.0 1.0 6 Q9GZT9,P13674 2 +Cyclin dependent protein serine threonine kinase activator activity 0.7379104477611973 0.419835193660469 0.674605853070932 1.0 1.0 2 P14635 1 +Phosphatidylinositol monophosphate phosphatase activity 0.4279091506001682 0.4197788111274422 0.6746470452784292 1.0 1.0 4 Q8NCE2 1 +Enzyme activator activity 0.2735086659506593 0.4188827589964086 0.6753018179174466 1.0 1.0 107 P41440,Q9P2J5,Q8N6T3,P35251,Q9H6U6,P52564,P50395,P46940,Q9UER7,O14737,Q9H3U1,O00487,Q9Y376,O60343,P68036,Q9UBE0,Q14997,O00429,P36507,Q15436,Q9Y3P9,P61289,Q9BTW9,P49407,P21359,Q9Y263,Q15257,Q13043,Q86X10,P60983,P24386,Q15334,Q14185,A1X283,O75569,Q16186,P43487,P42574,Q9H8V3,Q9NVG8,P35269,Q8TC07,O75909,Q69YN2,Q14738,P14635,Q01968,P13010,Q14C86,Q15042 50 +Histone binding 0.255431686460882 0.4169578292544194 0.6767092534866452 1.0 1.0 90 Q96EB6,Q01105,Q03164,P42695,Q06787,Q9BUR4,Q14997,O14929,A3KN83,Q9UER7,Q5VTR2,Q7Z4V5,Q96P70,Q16512,O75607 15 +Nucleoside diphosphatase activity 0.5246149643994439 0.4064501311742282 0.6844118915978639 1.0 1.0 3 Q9UKK9 1 +Neurotrophin receptor binding 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 1.0 2 P19174 1 +Neurotrophin trk receptor binding 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 1.0 2 P19174 1 +Anaphase promoting complex binding 0.7301492537313484 0.4001671711673015 0.6890333925980601 1.0 1.0 2 Q16763 1 +Carbon nitrogen ligase activity with glutamine as amido n donor 0.344158057249231 0.3998933072653221 0.6892351019528224 1.0 1.0 8 O15067,P08243,P27708 3 +Galactosyltransferase activity 0.4219143827843276 0.3995102444017705 0.6895172768263758 1.0 1.0 4 O43505 1 +Peptidyl proline 4 dioxygenase activity 0.4193395238892822 0.3909440580403891 0.6958385867421357 1.0 1.0 4 Q9GZT9 1 +Atpase binding 0.315177921263156 0.3901953507689706 0.696392099256725 1.0 1.0 31 Q16740,Q9Y487,Q08209 3 +Inorganic diphosphatase activity 0.7238805970149282 0.3846173655916615 0.7005209262027423 1.0 1.0 2 Q9H2U2 1 +Gtpase activating protein binding 0.3923042561753188 0.3820704284341553 0.7024091255859304 1.0 1.0 5 P07437,Q14C86 2 +Molecular carrier activity 0.3076218406120884 0.379996929444167 0.7039476944504226 1.0 1.0 34 O75880,O00629,Q9Y5L0,Q96P70,Q9HAV4 5 +Kinetochore binding 0.5146346911522108 0.378118941896566 0.7053422375191456 1.0 1.0 3 Q7Z460 1 +Phosphatidylcholine binding 0.3366692053599908 0.3710901619087756 0.7105703783836432 1.0 1.0 8 Q00169 1 +Nitric oxide synthase regulator activity 0.7176119402985106 0.369376201960742 0.7118473338331321 1.0 1.0 2 P07900 1 +Ubiquitin ubiquitin ligase activity 0.3648042203861876 0.3684093420641421 0.7125680326176855 1.0 1.0 6 O95071 1 +Aspartic type peptidase activity 0.3881800651617305 0.3680538462999158 0.7128330842705664 1.0 1.0 5 P42574 1 +Transcription coregulator binding 0.3158376693262569 0.3661373410074164 0.7142625950806238 1.0 1.0 26 Q15648,Q15369,P51784,Q9UQB8 4 +Phosphatase regulator activity 0.3137684878667671 0.3568451934949122 0.7212077011000719 1.0 1.0 26 Q01105,Q8TF05,P63151,Q15257,P30154,Q9Y570,P35269,Q14738,Q9BTT0 9 +Phosphatidylinositol phosphate kinase activity 0.7077611940298543 0.3460676651391999 0.7292918632152874 1.0 1.0 2 O00443 1 +Adp ribose diphosphatase activity 0.6994029850746313 0.3269243170271229 0.7437251284632604 1.0 1.0 2 Q9UKK9 1 +Non membrane spanning protein tyrosine phosphatase activity 0.6976119402985124 0.3228995657098765 0.7467713052241041 1.0 1.0 2 Q06124 1 +Intramolecular transferase activity 0.2965415683683448 0.3219373069964508 0.7475001896168685 1.0 1.0 11 P18669,P48449 2 +Annealing activity 0.3076973989977937 0.3172980570456609 0.7510174515094812 1.0 1.0 9 Q06787,P51114,P46063 3 +Translation repressor activity 0.3075258570680915 0.3166815948852742 0.7514852156992069 1.0 1.0 9 Q06787 1 +Frizzled binding 0.6946268656716454 0.3162531968660453 0.7518103328395005 1.0 1.0 2 Q15334 1 +Endopeptidase regulator activity 0.3041142295256068 0.3118450054581654 0.7551583189108066 1.0 1.0 24 Q9C0C9,Q9NR09,Q16186,P04080,P61289,P61201,Q9Y5K5,P30086,O00487 9 +Protein phosphatase regulator activity 0.3034862864851146 0.3093071970630136 0.7570878567632844 1.0 1.0 21 Q01105,Q8TF05,P63151,Q15257,P30154,Q9Y570,Q14738 7 +Dioxygenase activity 0.3021141616877307 0.3032266670120964 0.7617171277716177 1.0 1.0 23 Q7LBC6,Q9GZT9,Q6P6C2,Q9C0B1,O00625,Q32P28,P13674 7 +Transcription corepressor activity 0.2048097432076475 0.3026247717775612 0.7621758340271632 1.0 1.0 57 O75182,Q96EB6,Q04727,Q6W2J9,Q96IZ0,Q9BQ70,O14744,Q9UER7,P09429,P61201,Q15648,P27695 12 +Map kinase kinase kinase activity 0.6868656716417967 0.29933723009385 0.7646827505807035 1.0 1.0 2 O43318 1 +Peptidase activator activity involved in apoptotic process 0.4835022874646248 0.296432664536259 0.7668996829736803 1.0 1.0 3 Q9UKL3 1 +Folic acid transmembrane transporter activity 0.6847761194029913 0.2948740136154752 0.7680901238933959 1.0 1.0 2 P41440 1 +Phosphoserine residue binding 0.386778569919915 0.2905264007112288 0.771413556473407 1.0 1.0 4 P31946 1 +Monosaccharide binding 0.2936931739253049 0.2822000012717109 0.7777901573452959 1.0 1.0 29 P11413,P51570,P04075,P08237,Q9GZT9,O60568,P17858,Q32P28,P06737,P13807,P13674 11 +Protein tyrosine kinase binding 0.2956735191716905 0.2795881655261139 0.7797934876887058 1.0 1.0 21 P07900,O43318,P46109,Q13501,P51452,Q06124,Q14152,P22681 8 +Phosphotransferase activity phosphate group as acceptor 0.2862417908034654 0.2727054729368782 0.7850796273207237 1.0 1.0 13 Q15126,P15531,P00568,P22392,Q00013 5 +Phosphoprotein binding 0.2909423524940844 0.2712920082825595 0.7861664525416265 1.0 1.0 29 P62993,P31946,P43034,O15344,Q9UHD2,P28482,P46109,P07737,Q8IWS0,P29372,Q06124,P22681 12 +Regulatory rna binding 0.2902508489821275 0.2635877466913303 0.7920976014315877 1.0 1.0 19 Q5TAX3,P67809,Q8IWR0 3 +Structural constituent of cytoskeleton 0.2867191329843375 0.2632878758143924 0.7923287038253768 1.0 1.0 31 O15020,Q9Y5K6,Q16204,P04350,P07437,Q96CW5,Q9BUF5,Q9UEY8,Q13885,Q9Y490 10 +Ubiquitin binding 0.2887205505883397 0.2626841608355034 0.7927940259968707 1.0 1.0 29 Q9Y3I1,Q9H4L7,Q9Y263,Q04323,O43684,O95071,P45974,Q9UJY4,Q96FW1,Q13501,Q8TAT6,Q16186 12 +Gtpase inhibitor activity 0.330328263883633 0.2566929564248783 0.7974158093648984 1.0 1.0 6 O00410,P46940,O43924 3 +Ligase activity forming carbon nitrogen bonds 0.2893422938269559 0.2559031905656858 0.7980255909236322 1.0 1.0 22 P11586,P30520,P49915,P17812,P48506,P08243,P27708,O15067,P48507 9 +Hydrolase activity acting on carbon nitrogen but not peptide bonds 0.283860615686646 0.2416856357954145 0.8090237606314568 1.0 1.0 28 Q96EB6,P00813,Q9BPU6,Q9NQR4,Q01433,P27708,Q8IYS1,P31939 8 +Peptidase regulator activity 0.2782602794432058 0.2276893300966366 0.8198877679383914 1.0 1.0 30 Q9C0C9,Q9NR09,Q16186,P04080,Q14997,P61289,P61201,Q9Y5K5,P30086,O00487 10 +Glutamate receptor binding 0.30646429184731 0.2265120830435466 0.8208031625236432 1.0 1.0 7 P41440 1 +Vitamin d receptor binding 0.3059302147423897 0.2250336089941727 0.8219531285275061 1.0 1.0 7 Q9Y2X0 1 +Ribonucleoprotein complex binding 0.2273780813336681 0.2223899497499299 0.8240103348852814 1.0 1.0 90 P09012,P61221,O76094,Q9BXJ9,Q06787,P41567,Q7Z478,Q9NTK5,P38935,P46379,P46199,Q8IWS0,Q96E11,Q9BY44,Q6PKG0,Q8TEQ6,P63241,O60678,P13639,Q9HAV4,Q92616,P60059,P15531,Q96D46,O94822,O14744 26 +Ionotropic glutamate receptor binding 0.3167736562379497 0.2188277699332298 0.8267842138125385 1.0 1.0 6 P41440 1 +2 oxoglutarate dependent dioxygenase activity 0.2756442821186561 0.2159424313206339 0.8290326218772388 1.0 1.0 19 Q7LBC6,Q9GZT9,Q6P6C2,Q9C0B1,Q32P28,P13674 6 +Glutathione transferase activity 0.3019698257961475 0.2142659878461715 0.8303396398623342 1.0 1.0 7 P78417 1 +Cyclin binding 0.2693511015432459 0.2141562939184507 0.8304251777537894 1.0 1.0 14 Q9UII4,Q9NYV4,Q13618,P11802,Q00534 5 +Ubiquitin like protein binding 0.2656796934221857 0.2128749693855087 0.8314244864467033 1.0 1.0 36 Q9Y3I1,Q9H4L7,Q9Y263,Q9UBT2,Q04323,O43684,O95071,P45974,Q9UJY4,Q96FW1,Q13501,Q8TAT6,Q16186 13 +Lipase activator activity 0.4452303860986097 0.2115021585224496 0.8324954480524176 1.0 1.0 3 Q9Y263 1 +Camp binding 0.4437145416542226 0.2085158358547245 0.8348262191504126 1.0 1.0 3 P10644,Q9Y4G8 2 +Carbon nitrogen lyase activity 0.3331099161289488 0.2072252522400136 0.8358339468864044 1.0 1.0 5 Q8WUX2 1 +Guanylate kinase activity 0.3536439665471814 0.2052783978284139 0.8373546207019307 1.0 1.0 4 Q9UDY2,Q12959,Q00013 3 +Hsp90 protein binding 0.2715088210982881 0.2036848566820118 0.8385997767401574 1.0 1.0 19 O95801,Q08752,Q00535,O94966,Q9Y4R8,P68400,Q15185,O95433,P31948,Q9H3U1,Q9UHD1,Q16543 12 +Translation termination factor activity 0.634029850746274 0.1988941859452072 0.8423455176019363 1.0 1.0 2 P62495 1 +Histone acetyltransferase binding 0.3089071519661553 0.1985514685524507 0.8426136201210439 1.0 1.0 6 Q9H6U6,O95905 2 +Transferase activity transferring alkyl or aryl other than methyl groups 0.2716136647031273 0.1980966513835091 0.842969444728723 1.0 1.0 23 Q9NR45,Q9BQC3,P24386,Q92696,P08397,P31153,Q96EY8,P19623,P78417,P28161 10 +Thioesterase binding 0.4377426097342531 0.1970389159856688 0.8437970841455114 1.0 1.0 3 P60953,Q12933 2 +Lactate dehydrogenase activity 0.6322388059701547 0.1959549435302278 0.8446454320786476 1.0 1.0 2 P00338 1 +L lactate dehydrogenase activity 0.6322388059701547 0.1959549435302278 0.8446454320786476 1.0 1.0 2 P00338 1 +Phosphodiesterase i activity 0.6310447761194091 0.1940127254930262 0.8461659177225949 1.0 1.0 2 P27695 1 +S adenosyl l methionine binding 0.6307462686567218 0.1935293314539411 0.8465444370630522 1.0 1.0 2 Q99873 1 +Deoxynucleoside kinase activity 0.6301492537313489 0.1925651365120271 0.8472995508800345 1.0 1.0 2 P04183 1 +Transcription coactivator activity 0.2196516096789056 0.1874065736900818 0.8513418688559213 1.0 1.0 89 P53999,Q96EB6,Q9UPT9,O00170,Q16512,Q92905,P68036,Q9Y2X0,Q05086,Q9UER7,Q14258,P09429,Q5VTR2,Q6P1K2,P19474,Q86TU7 16 +Phosphoric diester hydrolase activity 0.253566084731483 0.1853834312595311 0.8529283031183359 1.0 1.0 11 P19174,P27695 2 +Modified amino acid binding 0.2626773234498086 0.1772857067373914 0.859283977333209 1.0 1.0 20 Q8WTV0,P41440,P00374,P09429,P49327,P28161 6 +Ribonuclease activity 0.2160339878617236 0.1764736596388678 0.8599218404763584 1.0 1.0 50 Q9Y2L1,Q96C86,Q9UQ84,Q9Y3Z3,Q99575,O75792,O15091,O75818,Q9UIV1,P39748,Q6L8Q7,Q9UPY3,Q96F86,A5YKK6,P27695 15 +Carbon carbon lyase activity 0.2634178139432415 0.1761811398886429 0.8601516372107079 1.0 1.0 22 P11172,Q9H993,P04075,P09972,Q9NZB8,Q6P996,P48163,P30046,P53602,P06132 10 +Death domain binding 0.423111376530308 0.1708774777435232 0.8643201063387498 1.0 1.0 3 Q13546,P63244 2 +Calcium dependent protein kinase activity 0.4199778068088933 0.1656374592720371 0.8684422662291498 1.0 1.0 3 Q16512 1 +Protein kinase c activity 0.4199778068088933 0.1656374592720371 0.8684422662291498 1.0 1.0 3 Q16512 1 +Centromeric dna binding 0.3348749450062632 0.1653555338131334 0.8686641506911197 1.0 1.0 4 O43264,Q99661 2 +Cyclic nucleotide dependent protein kinase activity 0.3345280764635466 0.1646764640923176 0.8691986429741421 1.0 1.0 4 P17612,P54619,Q12802 3 +Camp dependent protein kinase activity 0.3345280764635466 0.1646764640923176 0.8691986429741421 1.0 1.0 4 P17612,P54619,Q12802 3 +7s rna binding 0.281016442451433 0.1631600350568864 0.8703924318875811 1.0 1.0 7 Q9UHB9,P37108,P61011,O76094,Q13868,P09132 6 +Ribonucleotide binding 0.2394954334546855 0.1624292048945115 0.8709678740240372 1.0 1.0 606 Q05639,P33992,Q00535,O95239,P62333,Q7Z460,P25205,P60953,Q9Y3Z3,P61020,P52564,Q99570,P48163,Q9BUF5,Q96EY8,Q92598,O75116,P54136,O14981,O60333,Q9H4L7,O60566,P38935,P14618,Q9Y6B6,P26196,P26639,P49427,P46199,P11802,P46063,Q92499,O60942,Q00169,Q15382,Q92620,Q96SB4,P18858,Q99661,P78362,Q9BW83,Q9C0C9,Q9Y4B6,Q8IX18,P31751,P61086,O14646,P04183,P13639,P14735,Q14240,P17987,Q13535,Q9BYN0,P51570,Q9H4M9,Q9BZX2,P50570,P45985,P36404,P26640,P17812,Q9NVE7,Q8N3Z3,Q15477,Q8N3C0,P42356,Q14204,Q14527,Q9Y285,P49770,Q9Y295,Q9P2J5,Q9P0V9,Q9P0J0,Q6IBS0,P27708,Q96Q89,P22392,P22314,Q16512,O96017,P23921,O15111,Q13572,O00442,P30520,Q9NTK5,Q6P158,P49915,P61081,P48506,P47897,P41252,Q969G6,P49903,Q2NKX8,Q8IV63,O00154,Q15257,Q96I59,Q9BVQ7,P07741,Q9NTJ3,Q9HD20,O43237,P30086,Q9HCE1,Q16513,Q7Z7L1,P11586,P36915,P15531,P35790,A0AVT1,Q00534,Q9Y620,Q13885,Q01813,Q8TCY9,P62195,O15067,Q16763,P52732,P48643,P49761,P41440,P62191,Q16539,P18074,Q96KB5,Q9UG63,Q7Z478,Q14166,Q9HCK8,Q9BSD7,Q9UBT2,P68036,O00429,P17858,P07814,O43318,P11908,P08243,P33176,O60231,P31689,P54577,P49642,P19784,P49368,P35579,Q15126,Q8TBC4,Q8TB37,Q8NFF5,Q9Y5Y2,Q13283,P20585,Q04637,Q13057,Q9UPY3,Q7L014,Q7Z7E8,Q9UJ70,Q86WJ1,Q8NE71,Q9NR31,Q9BTE6,Q13153,Q99986,P07900,P00568,O95347,Q9Y450,O75351,O00764,P68371,P43686,P61221,P54277,P35251,P33981,P41240,P53350,Q8TD19,Q6PL18,Q92900,Q92614,Q7Z2Z2,Q9H6S0,Q96DE0,Q9Y6G9,O60841,P08237,Q9NRZ9,P36507,P42694,P53396,P13984,P08238,O00178,O00443,Q9NSD9,Q9NUL7,O43683,P33991,Q13555,Q13464,Q15645,Q13043,O14965,O43776,Q14141,P55010,P49591,P04350,P43246,P07437,Q8TBX8,P51003,P52701,P28482,Q5T9A4,Q14012,Q99741,Q9NYV4,Q9UHD2,Q9NUQ8,Q15058,Q9H2G2,P49589,O60884,P06737,P12277,P30085,P23381,P17612,P13010,P00558,Q0VDF9,P53602 242 +Transferase activity transferring phosphorus containing groups 0.3130425928177548 0.1613580598686865 0.871811397134225 1.0 1.0 208 Q00535,Q7Z460,Q99570,O75116,Q9NW08,O60566,P14618,P11802,O60942,Q96SB4,P78362,Q9BWH6,Q9Y4B6,P31751,P04183,P13807,Q13535,P51570,P45985,Q9BZX2,Q2VPK5,Q9NVE7,P42356,Q5TAX3,P27708,P22392,Q16512,O96017,O60256,O15111,Q13572,P67870,Q969G6,P49903,P28340,Q8IV63,Q16513,P15531,P35790,Q07864,O15160,Q00534,Q01813,P49761,Q16539,Q96KB5,Q9BUI4,Q9NR45,P17858,O43318,P11908,P25440,P49642,P19784,Q15126,Q8NFF5,Q13057,Q9UJ70,Q13153,Q99986,P00568,Q9UKK9,O75909,Q13501,O00764,Q00013,P33981,P53350,P41240,Q8TD19,Q96IJ6,Q16222,O14802,P08237,P36507,O00443,Q14558,Q9NRN7,O43683,Q13555,Q13464,Q13043,O14965,Q8TBX8,P51003,P28482,Q86U90,Q14012,Q9Y4A5,Q9NYV4,Q9UHD2,Q9H2G2,P12277,P30085,P17612 95 +Nucleotidase activity 0.2883113882352863 0.151586271287606 0.8795132621917994 1.0 1.0 6 Q969T7,Q5TFE4 2 +Zinc ion binding 0.2655470218678649 0.1499514306250623 0.8808029346281419 1.0 1.0 150 Q03164,P34949,P00813,Q8N4Q0,P53004,Q9NUD5,Q9Y3Z3,Q5TAX3,Q9UNI6,P38935,P09960,Q9NY33,P26639,P26358,Q8IWV7,P19474,P29372,Q9H4A4,P49642,Q9UPT9,P10589,Q99707,O95071,P55786,O95376,P04183,Q00796,P14735,Q8N8N7,Q07864,O94822,Q13501,Q14527 33 +Metalloexopeptidase activity 0.2505171877434461 0.1463364131846133 0.8836558216853208 1.0 1.0 21 P09960,Q9NY33,P55786,P50579,Q9H4A4 5 +Protein phosphatase 2a binding 0.2363187004588652 0.1457174790274756 0.8841444223868109 1.0 1.0 11 Q9UPR3,Q15257 2 +Oxidoreductase activity acting on a sulfur group of donors 0.2515952190659907 0.1451740255310004 0.8845734732790067 1.0 1.0 27 Q9UHG3,O43396,P35754,Q9BYN0 4 +Rna adenylyltransferase activity 0.5967164179104543 0.1440812757371803 0.8854362902336474 1.0 1.0 2 Q96Q11 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.2828795218511801 0.1406965243116261 0.8881096909802213 1.0 1.0 6 Q9UHG3 1 +Sumo binding 0.2826205475907882 0.1401929688786615 0.8885075270657057 1.0 1.0 6 Q9UKL3,Q9UBT2 2 +Thioredoxin disulfide reductase activity 0.5934328358209021 0.1398992613287269 0.8887395849242401 1.0 1.0 2 Q16881 1 +Poly purine tract binding 0.2406543606520371 0.1398151845789047 0.8888060155841608 1.0 1.0 15 Q92499,Q86TB9,Q06787,Q13310 4 +Ferrous iron binding 0.3209294563162899 0.139739521589937 0.8888657990371371 1.0 1.0 4 Q9GZT9 1 +Adenyl nucleotide binding 0.2592782621161172 0.1387348069703845 0.8896597120754204 1.0 1.0 504 P33992,Q00535,O95239,P62333,Q7Z460,P25205,P52564,Q99570,P48163,Q96EY8,Q92598,O75116,P54136,O14981,O60333,Q9H4L7,O60566,P38935,P14618,P26196,P26639,P49427,P11802,P46063,Q92499,O60942,Q00169,Q92620,Q96SB4,P18858,Q99661,P78362,Q9C0C9,Q9Y4B6,Q8IX18,P31751,P61086,O14646,P04183,P14735,Q14240,P17987,Q13535,Q9BYN0,P51570,Q9H4M9,Q9BZX2,P45985,P26640,P17812,Q9NVE7,Q15477,Q8N3C0,P42356,Q14204,Q14527,Q9Y285,P49770,Q9P2J5,Q9P0J0,Q6IBS0,P27708,Q96Q89,P22392,P22314,Q16512,O96017,P23921,O15111,Q13572,O00442,Q9NTK5,Q6P158,P49915,P61081,P48506,P47897,P41252,Q969G6,P49903,Q2NKX8,Q8IV63,O00154,Q15257,Q96I59,Q9BVQ7,Q9UL15,P07741,Q9NTJ3,Q9HD20,O43237,P30086,Q9HCE1,Q16513,Q7Z7L1,P11586,P15531,P35790,A0AVT1,Q00534,Q9Y620,Q01813,P62195,O15067,Q16763,P52732,P48643,P49761,P41440,P62191,Q16539,P18074,Q96KB5,Q9UG63,Q7Z478,Q14166,Q9HCK8,Q9BSD7,Q9UBT2,P68036,P17858,P07814,O43318,P11908,P08243,P33176,O60231,P31689,P54577,P19784,P49368,P35579,Q15126,Q8TBC4,Q8TB37,Q8NFF5,Q9Y5Y2,Q13283,P20585,Q04637,Q13057,Q9UPY3,Q7L014,Q7Z7E8,Q9UJ70,Q86WJ1,Q8NE71,Q9BTE6,Q13153,Q99986,P07900,P00568,O95347,O75351,O00764,P07737,P43686,P61221,P54277,P35251,P33981,P41240,P53350,Q8TD19,Q6PL18,Q92900,Q92614,Q9H6S0,Q9Y6G9,P08237,Q9NRZ9,P36507,P42694,P53396,P13984,P08238,O00443,Q9NSD9,Q9NUL7,O43683,P33991,Q13555,Q13464,Q15645,Q13043,O14965,O43776,P49591,P43246,Q8TBX8,P51003,P52701,P28482,Q5T9A4,Q14012,Q99741,Q9NYV4,Q9UHD2,Q9NUQ8,Q15058,Q9H2G2,P49589,O60884,P06737,P12277,P30085,P23381,P17612,P13010,P00558,Q0VDF9,P53602 212 +Growth factor receptor binding 0.2374806159086682 0.1367541489025038 0.8912251269170668 1.0 1.0 14 O00560,P62993,Q92990,Q9Y5K6,Q92600 5 +Amyloid beta binding 0.2675286803949707 0.1355642955892088 0.8921657328103356 1.0 1.0 7 Q8WTV0,Q99471 2 +Cyclohydrolase activity 0.3992170306323775 0.1341459614795011 0.8932871560552345 1.0 1.0 3 P31939 1 +Identical protein binding 0.2046479204429852 0.1329395958822447 0.8942411518189737 1.0 1.0 479 Q16740,P11310,Q03164,Q9UQB8,P38935,Q2TAA2,Q9UH99,Q86TI2,P55212,Q08AM6,O75569,O95352,Q9H4M9,Q9BZX2,Q01844,P17812,Q9Y613,Q9BUR4,Q96Q89,P23921,Q8TCG1,P67870,P49903,O00154,Q14790,Q15257,Q9Y5L0,Q00796,O43237,P43490,Q92734,P15531,P35790,P42858,P53999,P49761,P09012,P61970,Q06787,Q96F86,O00429,P17858,O43318,P61289,P19474,P29372,P31939,P40763,Q96EB6,P20585,P49327,Q96C86,Q9H8V3,Q9UKK9,Q5VTR2,Q13501,P13674,P31946,P41240,Q96C23,Q15555,Q92547,Q96HR8,Q9UL63,Q13309,P11413,P08237,P00492,Q99873,Q66K74,Q15645,P52701,P28482,Q9BY32,Q9UHD2,Q9Y5K6,P49589,O14744,P06737,P30566,P28161,P53602 82 +Acid amino acid ligase activity 0.2785734239107992 0.1325080957880494 0.8945824199781982 1.0 1.0 6 P48506,P48507 2 +4 iron 4 sulfur cluster binding 0.2439071664997721 0.1300043433065693 0.8965629903943337 1.0 1.0 23 P28340,Q06203,P49643,P61221,Q8TB37,Q9Y5Y2,Q07864,P18074,P21399 9 +Phosphatidic acid binding 0.3947446999104197 0.1280886521202764 0.8980788163687148 1.0 1.0 3 Q9UNF0,Q9Y4G8 2 +Peptide receptor activity 0.5826865671641861 0.1269240815843271 0.8990004864354604 1.0 1.0 2 Q9NZT2 1 +Kinesin binding 0.2235842462714546 0.1257666311685248 0.8999166564616956 1.0 1.0 10 O43663,O43747,O60271,Q9H0B6,Q15334,Q96EK5,O60333 7 +Collagen binding 0.2484322660952759 0.1240699879999198 0.9012598606292792 1.0 1.0 8 Q16512,Q32P28 2 +Carboxy lyase activity 0.2311912925774219 0.1221578166755492 0.9027740336003908 1.0 1.0 15 P11172,Q6P996,P48163,P30046,P53602,P06132 6 +Insulin like growth factor receptor binding 0.3878769782024444 0.1192794782481766 0.9050539414013634 1.0 1.0 3 P49407,Q04917 2 +Thyroid hormone receptor binding 0.232482745631714 0.1188903539134734 0.9053622240188696 1.0 1.0 9 Q9Y2X0 1 +Procollagen proline dioxygenase activity 0.307735192632963 0.118661031809433 0.9055439104682456 1.0 1.0 4 P13674 1 +N acetyltransferase activity 0.2283288846395329 0.1173306257216664 0.9065980568173342 1.0 1.0 15 Q9UPT9,Q14CX7 2 +Nucleoside binding 0.2855856860608488 0.1133614089126938 0.9097440336661724 1.0 1.0 5 Q9NW08 1 +Dynein light chain binding 0.5674626865671709 0.1103714579558343 0.9121147880619224 1.0 1.0 2 Q96EX3 1 +Mitogen activated protein kinase kinase kinase binding 0.567164179104485 0.1100678738569568 0.9123555462654784 1.0 1.0 2 P60953 1 +Estrogen receptor binding 0.2170335646188368 0.1029350390954398 0.91801452821844 1.0 1.0 14 Q96T76,O43815,Q9Y4B6,Q969T9,P09874,Q15648,A5YKK6 7 +Molecular function regulator 0.2668281463789209 0.0943068449992563 0.9248654126283256 1.0 1.0 311 O00410,Q9UMX5,Q00535,P60953,P61020,P52564,P50395,P46940,Q9Y6D5,O00487,P11802,Q01105,Q9C0C9,Q9Y263,Q9P258,P80303,Q9Y570,P24386,Q14155,O75569,P51858,P30154,P35269,Q14C86,Q15042,Q9BTT0,P49770,Q9P2J5,Q9H6U6,O95067,Q14232,Q9UER7,P29692,O60256,O00401,Q8TF05,Q99996,Q14997,P47897,P67870,Q9BTW9,Q96BK5,Q92974,P21359,Q5H9R7,Q15257,Q86X10,Q92759,Q13144,Q9UL15,A1X283,P30086,P43490,Q16186,Q9Y2L1,O95373,P43487,Q9NPQ8,P62841,Q8TC07,P60510,P48507,P41440,Q8N6T3,Q92990,P42771,O14737,Q99615,Q9H3U1,Q9Y376,Q96N67,Q9NR09,P68036,O43242,O00429,P61289,P09429,P31689,P49407,Q14185,Q15334,P20248,Q9Y5K5,Q92616,Q9NR50,Q92538,P07900,Q9H8V3,P04080,O75909,Q69YN2,A4D1P6,Q01968,P07737,P14635,P78318,P60866,P31946,P63151,P53621,P61221,P35251,Q15008,P62081,O60343,Q9H9T3,P36507,Q15436,Q9Y3P9,P08238,Q14558,Q13464,Q13043,P60983,P55010,P61201,Q9NZL9,Q9NWR8,Q9NVG8,Q14738,O60884,Q02818,O95433,P23381,P42574,P13010,Q13200 127 +Poly pyrimidine tract binding 0.2121456528114062 0.0942848315638187 0.9248828988941618 1.0 1.0 15 Q86TB9,Q06787,P05455 3 +Enzyme regulator activity 0.2968431817709169 0.094052941698931 0.925067101688561 1.0 1.0 249 O00410,P52564,P50395,Q9Y6D5,O00487,P11802,Q01105,Q9C0C9,Q9Y263,Q9P258,P80303,Q9Y570,P24386,Q14155,O75569,P30154,P35269,Q14C86,Q15042,Q9BTT0,P49770,Q9P2J5,Q9H6U6,O95067,Q14232,Q9UER7,P29692,O60256,O00401,Q8TF05,Q14997,P47897,P67870,Q9BTW9,Q96BK5,Q92974,P21359,Q5H9R7,Q15257,Q86X10,Q13144,A1X283,P30086,Q16186,Q9Y2L1,O95373,P43487,Q9NPQ8,P62841,Q8TC07,P60510,P48507,P41440,Q8N6T3,Q92990,P42771,O14737,Q9H3U1,Q9Y376,Q96N67,Q9NR09,P68036,O43242,O00429,P61289,P49407,Q15334,Q14185,P20248,Q9Y5K5,Q92616,Q9NR50,Q92538,P07900,P04080,Q9H8V3,O75909,Q69YN2,A4D1P6,Q01968,P14635,P78318,P60866,P31946,P63151,P35251,P61221,Q15008,P62081,O60343,Q9H9T3,P36507,Q15436,Q9Y3P9,P08238,Q14558,Q13464,Q13043,P60983,P55010,P61201,Q9NZL9,Q9NVG8,Q14738,Q02818,P23381,P42574,P13010,Q13200 109 +Alpha actinin binding 0.3648850403105393 0.0939920550563318 0.925115467943058 1.0 1.0 3 Q9NR12,Q96HC4 2 +Muscle alpha actinin binding 0.3648850403105393 0.0939920550563318 0.925115467943058 1.0 1.0 3 Q9NR12,Q96HC4 2 +Ligase activity 0.2002795308052523 0.0937262623805672 0.9253266077411026 1.0 1.0 97 Q9P2J5,Q14258,P27708,P22314,P54136,O00442,Q14166,P30520,P49915,P26639,Q9UBT2,P07814,P48506,P47897,P41252,P08243,P54577,P18858,Q9NSD9,Q8TBC4,Q96I59,O43776,Q13564,O95352,P11586,P26640,A0AVT1,P17812,P49589,O15067,Q9Y285,P48507 32 +Ligase activity forming carbon sulfur bonds 0.215001959899025 0.0919398013822901 0.9267458684329716 1.0 1.0 18 Q9UBT2,A0AVT1,P22314,Q13564,O95352 5 +Glucocorticoid receptor binding 0.546865671641799 0.0912477030442227 0.927295771473313 1.0 1.0 2 Q02790 1 +Catalytic activity acting on a nucleic acid 0.2821037313351091 0.0892150302197963 0.9289110206215516 1.0 1.0 281 P25205,Q9Y3Z3,O15091,P54136,Q9NW08,Q9UQ84,O14981,Q9H4L7,P38935,P26196,P26639,P46063,Q92499,Q92620,P18858,Q9BWH6,Q8IX18,Q08J23,O14646,Q7Z4G4,Q14240,Q8N1G2,Q6P6C2,P26640,Q99575,Q96P11,Q8N3C0,Q15477,Q86W50,Q9Y285,Q14527,Q9P2J5,Q9C0B1,Q5TAX3,Q7L2J0,Q7Z2T5,O00442,Q6P158,O75818,P47897,P26358,P41252,P39748,Q2NKX8,P28340,Q96I59,Q9UIV1,Q9UET6,P57081,Q7Z7L1,Q9Y2L1,Q9UBP6,P15531,Q07864,Q9Y620,Q96FZ2,P41440,P18074,Q96F86,Q7Z478,Q9BUI4,O60231,P29372,P49642,Q7L014,Q86WJ1,Q96C86,P27695,Q92614,Q9BV44,Q9H6S0,O14802,P42694,Q9NSD9,Q9NUL7,Q66K74,O43776,O60294,P52701,Q8TEA1,Q6P1R4,Q9NUW8,P49589 83 +Amino acid binding 0.2053507648920957 0.0886431006789404 0.9293655534987008 1.0 1.0 14 P54136,P27708,Q8IWV7 3 +Signaling adaptor activity 0.2121516745172328 0.0886200601149335 0.9293838651434728 1.0 1.0 18 P36507,P40763,Q06124 3 +Transcription corepressor binding 0.2047558342063069 0.0880048065616109 0.9298728558838354 1.0 1.0 14 P51784,Q15369 2 +Hydrolase activity acting on acid anhydrides 0.1515083862256027 0.0876448368020646 0.930158964658357 1.0 1.0 283 Q05639,P41440,Q9Y295,P54277,P25205,Q6PL18,P18074,Q9BUF5,Q92614,Q96Q89,Q9H6S0,O14981,O60333,Q7Z478,Q9H4L7,Q9NTK5,P38935,Q6P158,Q9BSD7,Q9Y6B6,P26196,O60841,P33316,P46199,P46063,Q92499,O00429,O60942,Q15382,Q92620,O60231,Q99661,Q9BW83,Q9NUL7,Q15645,Q9Y5Y2,Q8IX18,P04350,P07437,O14646,P13639,Q14240,P17987,Q7L014,Q7Z7L1,Q86WJ1,P50570,Q9BY32,Q96C86,P36404,P36915,Q9H2U2,Q9UKK9,Q15058,Q9Y450,Q8N3C0,P35080,Q0VDF9,Q14527 59 +Enzyme inhibitor activity 0.1789911682914419 0.0872586567131321 0.93046591578843 1.0 1.0 76 O00410,P60866,P31946,P61221,Q92990,P42771,O60256,P62081,Q9NR09,P47897,Q96BK5,Q14558,P49407,Q01105,Q9C0C9,Q13464,P60983,Q9Y570,P61201,Q9Y5K5,P30086,P04080,P23381,P42574,P62841,Q9BTT0 26 +Cytoskeletal motor activity 0.2190059104747524 0.0872479029630416 0.930474463440378 1.0 1.0 28 P35579,Q13526,O60333,Q15058,P33176,Q96Q89,Q14204,P52732,Q99661 9 +Adrenergic receptor binding 0.2819593787335629 0.0859887307123212 0.9314753756327632 1.0 1.0 4 Q9Y4G8,O14745,Q15334 3 +Catalytic activity acting on rna 0.2672192796528597 0.0859853107185293 0.931478094323722 1.0 1.0 201 Q9P2J5,Q9Y3Z3,Q9C0B1,O15091,Q5TAX3,Q9BV44,P54136,Q9NW08,Q7L2J0,Q9UQ84,Q7Z2T5,Q96F86,Q9H6S0,Q7Z478,O00442,Q9BUI4,O14802,P38935,Q6P158,P26196,P26639,Q92499,O75818,P47897,P41252,Q92620,P39748,O60231,P49642,Q9NSD9,Q9NUL7,Q9BWH6,Q96I59,O43776,Q8IX18,Q08J23,O60294,Q9UIV1,Q9UET6,Q7Z4G4,Q14240,Q7L014,P57081,Q8TEA1,Q6P1R4,Q8N1G2,Q9Y2L1,Q9UBP6,Q96C86,Q6P6C2,P26640,Q99575,Q96P11,P49589,Q9Y620,Q15477,Q86W50,Q9Y285,P27695 59 +G quadruplex dna binding 0.2483562462641903 0.0858398764588072 0.9315937066201314 1.0 1.0 6 Q9H2U1,P54132,Q8IZH2,P22392,Q92878 5 +Cytoskeletal protein binding 0.2471003253625451 0.084020603467293 0.9330400504908204 1.0 1.0 266 Q00535,Q14331,P17655,Q7Z460,Q96IZ0,Q9BT25,O75116,Q9Y6D5,P47755,O60333,Q9BPU6,P09972,Q9UH99,Q96CW5,Q8IWS0,Q86TU7,Q99661,Q9P258,Q14155,Q9P265,Q9H269,P50570,P43034,Q8TD16,Q9Y613,Q15398,Q9BPX3,Q9Y295,Q9H6U6,Q9H6H4,Q9H0B6,Q6IBS0,Q96Q89,Q16512,O15020,O00401,P04075,P35611,Q9BTW9,Q96TC7,Q92974,Q99439,Q7Z4H7,Q9BSJ2,Q9UEY8,Q9HC35,O60610,P42858,Q15691,P52732,P48643,P47756,Q6NUK4,Q15813,O14737,P78559,Q06787,Q9NZQ3,Q14166,Q14008,O15344,O00429,P33176,P16949,P51452,P35241,P29372,P60981,P35579,Q15334,Q14203,Q9Y490,Q13153,Q03001,P07900,Q9Y5X3,P07737,P27695,Q15555,Q92614,P57737,Q96AC1,Q66K74,O15357,Q15058,P35080 86 +Nucleobase containing compound kinase activity 0.2051325815197001 0.0812890242438072 0.9352121024879778 1.0 1.0 18 Q9BZX2,P15531,P00568,P04183,P22392,Q00013 6 +Aspartic type endopeptidase inhibitor activity 0.5319402985074707 0.0795998063329971 0.9365555492532948 1.0 1.0 2 Q13464 1 +Transferrin receptor binding 0.2744922341696403 0.0784970428820005 0.9374326824047254 1.0 1.0 4 O60749,Q13596,O15111 3 +Udp glucosyltransferase activity 0.2276908319914931 0.0775215930178138 0.9382086142164698 1.0 1.0 7 P13807 1 +Atp dependent activity 0.156420873964316 0.0772742620217575 0.9384053656020824 1.0 1.0 238 Q16740,P41440,P54277,P25205,Q9Y5K8,Q6PL18,P18074,Q92614,Q96Q89,Q9H6S0,O14981,O60333,Q7Z478,Q9H4L7,Q9NTK5,P38935,Q6P158,P26196,P42694,P46063,Q92499,Q92620,O60231,Q99661,Q9NUL7,Q15645,Q9Y5Y2,Q8IX18,O14646,P52701,Q14240,Q7L014,Q7Z7L1,Q86WJ1,Q15058,Q9Y620,Q15477,P35080,Q0VDF9,Q14527 40 +Cell adhesion molecule binding 0.1928355301636906 0.0763621060681329 0.939131016522579 1.0 1.0 234 O00560,Q9UQB8,P50914,P54136,O00299,O75874,P14618,P26196,Q96TA1,Q9BY44,Q9Y570,P13639,Q9H4M9,P42356,Q14C86,Q9BPX3,Q9H0B6,O95067,Q6IBS0,P29692,P22681,O15020,P04075,Q9NTK5,P35611,Q8TCG1,P40818,Q6Y7W6,Q99439,Q9HC38,Q16513,P15880,P05198,P43487,P46109,Q01813,Q15691,P47756,Q15056,Q14258,Q9H3U1,Q7Z478,Q14008,P63104,P62854,P33176,P09429,P35241,P31939,P47914,P35579,Q6P996,P20248,P49327,Q06124,Q9Y490,Q92616,Q03001,Q9Y5X3,O60664,P07737,P15311,P26641,P62750,P31946,Q00341,P08238,Q96AC1,O14562,P78344,Q6PKG0,P83731,P55010,Q9Y5K6,Q9NUQ8,Q9H2G2,O95433,Q14677 78 +Beta catenin binding 0.1918951258575937 0.0745393287602909 0.9405812483658902 1.0 1.0 15 Q9HCK8,Q8WZA0,Q13526,Q9Y5K6 4 +Kinase binding 0.2433693590399849 0.0734212985856846 0.9414708695135484 1.0 1.0 193 Q05639,Q00535,P60953,P52564,Q96KP1,Q9UNI6,Q15382,Q9P258,Q9Y570,Q14155,P13639,P13807,P50570,Q9Y3I1,Q6IBS0,Q9UER7,Q92796,Q16512,O96017,P22681,P47897,P39019,Q9UL15,P30086,P42858,P46109,Q15691,P52732,Q16539,P42771,Q9Y376,P63104,P17858,O43318,P51452,P19474,P40763,Q96EB6,Q6IA86,Q9H6R7,Q9Y666,Q15334,Q14203,P20248,P49327,Q06124,Q92616,Q99986,P07900,O75909,Q13501,P15311,P14635,P18669,P62993,P53350,P41240,Q8TD19,Q15555,Q92600,Q14152,P62081,P08237,P19174,P08238,Q96AC1,Q99873,Q13526,Q13043,O14965,P43246,P30307,P50851,Q5VSL9,P62753,Q99741,Q04206,Q9NYV4,Q15058,Q00610,P23381,P17612 82 +Cadherin binding 0.2157088341448674 0.0716357597412602 0.942891781010218 1.0 1.0 212 P47756,P62750,P15311,P31946,Q00341,Q9UQB8,Q9H0B6,O95067,Q15056,Q6IBS0,Q14258,P29692,P54136,Q9H3U1,P22681,O00299,O15020,Q7Z478,O75874,Q14008,P04075,Q9NTK5,P63104,P14618,P26196,P35611,Q8TCG1,P62854,P08238,P33176,P35241,Q96TA1,P31939,O14562,P40818,Q9BY44,P47914,P35579,Q6Y7W6,P78344,Q6PKG0,Q99439,P83731,Q6P996,Q9Y570,P55010,P49327,P13639,Q06124,Q9Y490,Q9HC38,Q16513,Q92616,P15880,P05198,Q9H4M9,P43487,Q9Y5K6,Q9NUQ8,Q9H2G2,Q9Y5X3,P46109,O60664,Q01813,P42356,P07737,Q15691,Q14C86,Q9BPX3,P26641,Q14677 71 +Histone deacetylase activity h3 k14 specific 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 1.0 2 Q13547 1 +Actin filament binding 0.1681448394001267 0.0707627146232806 0.9435866068237276 1.0 1.0 73 P47756,P15311,Q14331,Q6IBS0,P46940,Q92614,P55196,P47755,Q7L576,P57737,O15020,P35611,Q96AC1,Q9UM54,P60981,P35579,Q66K74,Q13045,P61160,Q9UEY8,O15145,Q9Y490,Q9H269,Q14847,Q9Y613,P12814,Q9BPX3 27 +Transition metal ion binding 0.2030118699408881 0.0700659515060848 0.9441411668370332 1.0 1.0 206 Q03164,P34949,O75880,P00813,Q8N4Q0,Q9NQW7,P61221,P53004,Q9NUD5,Q9Y3Z3,Q9C0B1,Q5TAX3,Q9UNI6,P27708,P31350,P38935,P09960,Q9NY33,P26639,P45974,P26358,P39748,Q8IWV7,P19474,P29372,Q92974,Q9H4A4,P49642,Q9UPT9,P10589,Q99707,O95071,P55786,O95376,P04183,Q00796,P51003,P14735,O95487,P46976,P26572,Q8N8N7,Q9GZT9,Q07864,O94822,Q32P28,Q13501,P13674,Q14527 49 +Smad binding 0.1783400968607286 0.0699815286748925 0.9442083615697152 1.0 1.0 12 Q96AC1,Q93008,O95373 3 +Ubiquitin like protein ligase binding 0.202465255904304 0.0694942233231361 0.9445962306590584 1.0 1.0 119 Q9Y3I1,Q92990,Q9BUR4,Q93034,Q9UER7,Q92796,O96017,Q14999,Q13619,P63104,O15344,P68036,Q04323,O00429,P46379,Q96FW1,P29372,Q13617,P31689,Q9UPR3,P49407,Q8N0X7,Q14790,O14965,Q13618,P61086,Q9UL15,P07437,Q13564,P17987,Q8TAT6,O94966,O75150,P07900,Q5VTR2,Q13501,P12277,P14635,Q14527 39 +Adenylate cyclase binding 0.5161194029850831 0.0691243998591481 0.9448905991987748 1.0 1.0 2 Q01518 1 +Nadplus binding 0.2185351270553163 0.0687010490860191 0.945227583129002 1.0 1.0 7 Q96EB6,Q8IXJ6,P40939,Q16836,Q08426,Q7Z2W4 6 +Prenyltransferase activity 0.2170403587444047 0.0674028943239783 0.9462609650937426 1.0 1.0 7 Q86YH6,P24386,Q92696,P14324,O95749,Q9Y5Z9 6 +Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.1977871557086912 0.0655412397173097 0.94774307235683 1.0 1.0 32 P28340,Q9Y2L1,Q9UQ84 3 +Protein domain specific binding 0.1914414600149447 0.0648433339798521 0.9482987385028104 1.0 1.0 183 P41440,P31946,O00170,Q9UQB8,Q96K76,P20645,Q96Q89,Q6P1K2,P23921,P22681,P36507,P22059,Q96D71,Q96PU8,P67870,P31689,P40818,Q96EB6,Q14790,Q96T51,O15357,Q14185,P07437,P20248,P30307,A1X283,Q9Y5K6,P35269,Q13501,O95630,Q9Y613 31 +Signaling receptor binding 0.1845812968557611 0.0638482318948287 0.949091073078201 1.0 1.0 179 P68371,P62993,P41440,Q9UMX5,Q00535,O00170,P53621,Q92990,Q92600,Q14258,Q9BY49,Q9Y6D5,Q14152,O15111,P22681,Q9Y3F4,Q99996,Q9NXR7,Q96QK1,P19174,P46379,O43318,P30046,P08238,P09429,P67870,P51452,Q96AC1,Q15648,P31689,P54577,P40763,P49407,P35579,Q14790,Q15257,Q13043,O43776,Q13618,Q15334,P07437,P20248,Q06124,Q9Y490,P43490,P51858,P50570,Q03001,O60610,Q9Y5K6,Q9Y5X3,P46109,P14635,Q13501,O14654,P42574,P28161,P62195,Q00013,P27695 60 +Dna polymerase binding 0.1599317380301572 0.0637257956020461 0.9491885645680858 1.0 1.0 10 P09429,P07900,Q15185,P08238 4 +Atp hydrolysis activity 0.1688132304736725 0.063492394413544 0.9493744154047532 1.0 1.0 178 P62191,P41440,P43686,P35251,P54277,P25205,Q6PL18,Q92900,P18074,Q92614,Q96Q89,Q9H6S0,O14981,O60333,Q7Z478,Q9H4L7,Q9HCK8,Q9NTK5,P38935,Q6P158,P26196,P46063,Q92499,P13984,P08238,Q92620,P33176,O60231,Q99661,Q2NKX8,P49368,Q9NUL7,P33991,Q8TB37,Q15645,Q9Y5Y2,Q9BVQ7,Q8IX18,P43246,Q13283,O14646,Q0VDF9,Q9NTJ3,Q9HCE1,Q14240,P17987,Q7L014,Q7Z7L1,Q86WJ1,P07900,O95347,Q15058,O75351,Q8N3C0,P35080,P62195,P48643 57 +Guanyl nucleotide binding 0.192950430997423 0.0608849333861769 0.9514508485997132 1.0 1.0 120 P49770,Q05639,P41440,Q9Y295,Q9P0V9,Q9Y3Z3,Q9BUF5,P22392,Q9NTK5,O60841,Q9Y6B6,O00429,P46199,O60942,Q15382,P49903,Q9BW83,P04350,P07437,P13639,P50570,Q9H4M9,P36404,P36915,P15531,Q9Y450,Q8N3Z3,Q8TCY9 28 +Transcription coregulator activity 0.1996557831579621 0.0603389343876117 0.9518856932638288 1.0 1.0 151 P53999,O75182,O00170,P27695,Q96IZ0,Q9BQ70,Q9UER7,Q14258,Q6P1K2,Q16512,O14981,P68036,Q92499,O00625,P09429,Q7Z4V5,P19474,Q15648,Q86TU7,Q96EB6,Q9UPT9,Q7LBC6,Q15645,Q05086,P61201,Q96T76,Q92905,Q6W2J9,Q01844,Q9Y2X0,O14744,Q5VTR2,Q04727 33 +Exonuclease activity 0.1865284439269843 0.059738892252838 0.952363595494977 1.0 1.0 40 Q9Y2L1,P28340,Q96C86,Q9NUW8,Q07864,Q92499,P39748,Q9UQ84,P27695 9 +Adp binding 0.162608545894762 0.0550607791301256 0.956090042438606 1.0 1.0 21 P35579,P43246,P48163,P11908,P48506,Q92614,P52701,Q9UM54,P00558,Q9UHD1 10 +Telomeric dna binding 0.1398559423769438 0.0521304159166887 0.9584247775114813 1.0 1.0 20 P19338,Q9NYB0,Q92900,P12956,Q12888,P15927,P54132,P27694,Q9UPR3,Q9HAU5,Q92878,P22626,Q00577,O60341,Q9Y4R8,Q14103,Q15554,P13010,P27695 19 +Transmembrane transporter binding 0.1697585563033858 0.0510559245913269 0.9592809572376952 1.0 1.0 33 Q9Y4C2,Q99996,P63104,Q9HD26,O60610,P42858,Q14694,Q06787,P27695 9 +Calmodulin binding 0.1711648415099188 0.0506058520073253 0.9596395995749688 1.0 1.0 39 Q93100,Q5T4S7,P35579,Q13555,O43815,Q99439,P35611,Q01844,P46940,P32929,Q9UEY8,Q99797,P49327,Q9UM54,Q08209,Q14012 16 +Actin binding 0.1341938186116669 0.0497359319289284 0.9603328223416794 1.0 1.0 118 P47756,Q14331,Q96IZ0,Q6IBS0,Q92614,P78559,P47755,P57737,O15020,O00401,P04075,P35611,P35241,Q96AC1,Q86TU7,P60981,P35579,Q66K74,O15357,Q99439,Q9UEY8,Q9H269,Q9Y490,Q03001,O60610,P35080,P07737,Q9Y613,Q9BPX3 29 +Structural constituent of ribosome 0.1555429572291599 0.0491172568600399 0.9608258510198552 1.0 1.0 110 P46776,P84098,P62750,P60866,P62917,P62906,P61254,P61247,P50914,P46778,P62081,P32969,P62701,P27635,P62847,P08708,P62854,Q7Z7F7,P42766,P39019,P62269,P61513,P47914,P83731,P05387,P62753,P18621,P62899,P15880,Q9HD33,P39023,P62266,P46783,P62841 34 +G protein beta subunit binding 0.2535085100029777 0.0417147653094251 0.966726083192314 1.0 1.0 3 P63218,P48643 2 +Neurexin family protein binding 0.3534328358209028 0.0315765851243543 0.974809716440326 1.0 1.0 2 O00560 1 +Phosphatidylinositol 3 kinase activity 0.3155223880597065 0.0308439954850177 0.9753939537729948 1.0 1.0 2 O00443 1 +1 phosphatidylinositol 3 kinase activity 0.3155223880597065 0.0308439954850177 0.9753939537729948 1.0 1.0 2 O00443 1 +Ligand gated cation channel activity 0.3017910447761249 0.030729826707964 0.9754850041169548 1.0 1.0 2 Q96ER9 1 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..de668050cf08d80eca9422c5d4a84fb72fc43ab4 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Angiotensin receptor binding", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "Butyrate coa ligase activity", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calcium release channel activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonate dehydratase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol 1 4 5 trisphosphate binding", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intracellular ligand gated ion channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated calcium channel activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Microtubule severing atpase activity", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin heavy chain binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur amino acid transmembrane transporter activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo polymer binding", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRK1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C2CD5", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COG2", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAHD2A", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLYWCH2", "FMR1", "FN3KRP", "FNDC3A", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFKB2", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TLN1", "TMED10", "TMED9", "TMEM165", "TMEM201", "TMEM38B", "TMEM43", "TMEM70", "TMF1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS16", "VPS18", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WASF2", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZNF644", "ZNF703", "ZPR1", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AARSD1", "AASDHPPT", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACADM", "ACLY", "ACO1", "ACOT7", "ACP6", "ACTN1", "ACTR2", "ADA", "ADD1", "ADD3", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AHSA1", "AIP", "AK1", "AKAP13", "AKAP9", "AKR7A2", "AKT2", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC5", "ANKFY1", "ANP32E", "AP1G1", "AP3B1", "AP3M1", "APEX1", "APRT", "ARF4", "ARFGAP1", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARIH2", "ARL2", "ARMT1", "ARPC3", "ARRB1", "ASCC3", "ASNS", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP13A1", "ATP6V0A2", "ATP6V1D", "ATR", "AURKA", "B4GAT1", "BABAM2", "BAG5", "BAG6", "BAIAP2", "BCAS3", "BCCIP", "BCOR", "BICD2", "BIRC6", "BLM", "BLVRA", "BRD2", "BTAF1", "BUB1", "BUB1B", "BUB3", "CAB39", "CAD", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAPN2", "CAPZA2", "CAPZB", "CARHSP1", "CARS", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CBL", "CCDC51", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT3", "CCT5", "CD2AP", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC6", "CDK1", "CDK12", "CDK4", "CDK5", "CDK6", "CDKN2A", "CERS1", "CHAC2", "CHD1", "CHD1L", "CHD3", "CHD8", "CHEK2", "CHKA", "CHM", "CHORDC1", "CHUK", "CIP2A", "CKAP5", "CKB", "CLASP1", "CLIC1", "CLINT1", "CLK3", "CLPP", "CLTC", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "COASY", "COPA", "COPS2", "COPS5", "COPS6", "CORO1B", "CORO7", "CRKL", "CSDE1", "CSE1L", "CSK", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTH", "CTPS1", "CTU2", "CUL2", "CUL3", "CUL4A", "CUL5", "CUL7", "CWF19L1", "CYFIP1", "DAXX", "DCAF1", "DCPS", "DCTN1", "DCTPP1", "DDT", "DDX1", "DDX28", "DDX46", "DDX6", "DHCR24", "DHFR", "DHX16", "DHX29", "DHX36", "DHX38", "DHX40", "DHX57", "DIAPH1", "DICER1", "DIP2B", "DIS3", "DLG1", "DLG3", "DLGAP5", "DNAJA1", "DNAJA2", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DPH2", "DPP3", "DPP9", "DPYSL5", "DRG1", "DST", "DSTN", "DUS1L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLT1", "ECD", "ECT2", "EDC3", "EEF1A2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGLN1", "EHD1", "EHHADH", "EIF1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF3A", "EIF3D", "EIF3G", "EIF3L", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELOC", "ELP1", "ELP2", "ELP3", "EML4", "ENDOD1", "EPHX1", "EPRS", "ERCC2", "ERCC6L", "ETF1", "EWSR1", "EXO1", "EXOC2", "EXOSC2", "EYA3", "EZR", "FAF1", "FAM129B", "FAM98A", "FARSA", "FARSB", "FASN", "FBXO7", "FDPS", "FEN1", "FERMT2", "FHOD1", "FKBP4", "FLAD1", "FLII", "FMR1", "FOXK1", "FRG1", "FTO", "FTSJ1", "FXR1", "FXR2", "G3BP1", "G6PD", "GALK1", "GALM", "GAMT", "GAPVD1", "GARS", "GBF1", "GCLC", "GCLM", "GCN1", "GDI2", "GEMIN5", "GGA2", "GGPS1", "GIGYF2", "GLMN", "GLOD4", "GLRX", "GMFB", "GMPPA", "GMPS", "GNG5", "GNL1", "GNPDA1", "GOPC", "GRB2", "GSR", "GSTM2", "GSTO1", "GTF2F1", "GTF2F2", "GTF2H4", "GTPBP1", "GTPBP8", "GYG1", "GYS1", "HADH", "HADHA", "HAT1", "HAUS6", "HAUS8", "HBS1L", "HDAC1", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HECTD1", "HELLS", "HELZ", "HERC5", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB3", "HNRNPA2B1", "HNRNPD", "HPRT1", "HS1BP3", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA2", "HSPA8", "HSPH1", "HTT", "HUWE1", "IAH1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IFT27", "IGBP1", "IGHMBP2", "INPP4A", "INPPL1", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", 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2.0227564698821716 0.8448833540714317 0.8729968156041269 0.290854883922868 0.0883440144706526 0.172526836456327 0.3854765258786279 0.6307503726508297 +Stereotypy 25 73 2.5428296907280616 0.0109958810501418 16.16504854368932 68.16504854368932 -0.1457136226992207 0.7380594159098782 7.353220135210615 7.211569840246319 0.5630069023096004 0.2758698187864123 0.2283386821273668 0.1133319528150491 0.1927950950158071 0.0069498726687038 +Megaloblastic anemia 5 8 2.5323944442811475 0.011328647290119 2.0145631067961167 7.970873786407767 0.7711391111646035 0.4443874876374949 1.4991199856764053 0.7465949978845597 0.8631923197432491 0.3098803608602049 1.0 0.1323778037089543 0.3058660732099017 0.0005289198821125 +Macrocytic anemia 17 37 2.5314187957165 0.0113602118743569 10.618932038834952 35.41747572815534 0.0386714735659423 0.596736697300035 6.139394583324174 1.8500814563261656 0.988500669832288 0.3271589133359835 0.2030241760524146 0.0775893010395362 0.0296336619489011 2.672510894072328e-06 +Decreased circulating level of specific antibody 5 7 2.510429170418429 0.012058451007729 2.121359223300971 6.533980582524272 0.4932007596736456 0.4788575500117063 1.7193445627120678 1.458590448587382 0.9533329302475996 0.3207672834212082 1.0 1.0 0.0011637071015076 0.0002747300414667 +Congenital sensorineural hearing impairment 1 8 2.471017558006237 0.0134729203593777 1.9320388349514563 6.257281553398058 0.053826022586845 0.5371042549669027 1.5750613236471551 1.260613345997227 0.8935880670499209 0.2920891507307366 0.0798652174269664 0.1566927560007753 0.3547863423381785 0.2166689846253057 +Fatigable weakness of skeletal muscles 1 7 2.428784623516377 0.0151495288514249 2.4611650485436893 7.657766990291262 -0.5795512879074071 0.41268711091428 1.5123910863271102 1.2294378161439188 0.985647806648596 0.2819753082792458 0.092554689717322 0.1803331870597798 0.0895680133917324 0.2715157705871365 +Abnormal t cell subset distribution 7 13 2.3672521449354984 0.0179207189711192 3.6941747572815538 11.150485436893204 -0.1761601793259497 0.586445271308134 2.466998697081464 2.1714553209663245 0.8157298439247805 0.2920263213885655 1.0 1.0 0.0076999170588955 0.0203628052401783 +Abnormal scapula morphology 19 53 2.362560421576717 0.0181491826500379 13.060679611650484 51.39563106796116 0.0715702441844552 0.6973620722043212 5.3023815426244925 4.550288621999796 0.7178789707494411 0.30435988500742 0.0997216591997759 0.0961011545319798 0.0067806366434166 0.0001446177959819 +Abnormal middle phalanx morphology of the hand 1 7 2.328173284604925 0.0199029041567144 2.4563106796116503 7.589805825242719 0.5788196868209836 0.3824907194464522 1.617721633075034 1.3471267378138765 1.0880466646585885 0.2945011452106765 0.1690349275366953 0.0543070281832774 0.2497167706923579 0.5850817530243546 +B lymphocytopenia 4 11 2.2651639125018046 0.0235026227734764 1.9514563106796117 6.805825242718447 0.2546726583739481 0.4697103366525738 1.5304586581812405 1.3903848208472418 0.9940756560414792 0.2977574699838766 1.0 1.0 0.0170176746213231 0.0042957165481444 +Focal non motor seizure 5 10 2.255596580857057 0.0240959075479985 2.779126213592233 9.473300970873789 0.0084656133548897 0.6464403812634476 2.065023381609613 1.237271417233086 0.6882627629188746 0.2666918927057338 1.0 0.3155444220122531 0.0150956780286917 0.0428945912137629 +Abnormality of the menstrual cycle 12 57 2.239640627179974 0.0251142629388567 12.364077669902912 51.6747572815534 -0.1779158000483229 0.7456443246902413 5.697765775189328 5.253851448049815 0.5828999352354801 0.276355291907422 0.1696190002440116 0.1935662792825409 0.0156175613181856 0.0494509389460782 +Cessation of head growth 3 7 2.237152751779888 0.025276358198377 2.7135922330097086 6.359223300970874 0.2589736350283335 0.5177350212098878 1.7377894977759678 0.8657940844904278 0.9606340624604344 0.3200420674732117 1.0 0.0017865936405575 1.075765402375085e-05 0.0001708540892308 +Decreased plasma carnitine 2 13 2.235073296124966 0.0254125371816829 3.1723300970873787 11.83252427184466 0.7810684853101371 0.3882846400262963 2.088319668218202 0.9846444515726572 0.9843631004473848 0.2877502083970994 0.0023951619417497 0.0096613748096581 0.0060877577335729 0.0397387250697101 +Abnormal cd4 cd8 ratio 4 6 2.233388361598842 0.0255233450079905 1.7451456310679612 5.269417475728155 0.0767029318818461 0.5748884580502223 1.3367838262819711 0.7837776646828895 0.8265160427572792 0.2872436760226679 1.0 1.0 0.0014512760162947 0.0105668672564949 +Abnormal morphology of the limbic system 7 13 2.2312533884736867 0.025664349323609 3.3033980582524274 10.716019417475728 -0.0291878809110062 0.617198107759926 2.1571034396422943 2.124621195160194 0.7777912130960144 0.2842219686513498 0.2030241760524146 0.0775893010395362 0.0061967751678044 0.0089113675821019 +Deep plantar creases 1 5 2.2258814642055067 0.0260221222458867 1.8349514563106797 5.186893203883495 0.878985239421048 0.4043272377350911 1.2929764516183682 0.5365505235508999 0.7767472061372565 0.306948917766608 1.0 1.0 0.0553069748090555 0.1807018090276839 +Recurrent sinopulmonary infections 3 8 2.2057482056250115 0.0274016346304599 1.9029126213592231 6.769417475728155 0.225393755188534 0.5067941660863916 1.6938756795018022 1.0486869508388323 0.9269734110569616 0.2904667225933153 0.1255618233886208 0.2402159343378795 0.0316151554384263 0.0498364179528963 +Nonprogressive 3 7 2.18098064793064 0.0291848478760139 1.7548543689320388 6.233009708737864 0.5197538339444207 0.4920096159874214 1.3779120014158963 0.8089773419024573 0.8548269611597411 0.29929586178195 0.0583291306653072 0.1157837219692003 0.0376759114543004 0.0225979674873623 +Abnormal circulating iga level 8 17 2.176452220323315 0.029521462676147 3.5194174757281553 13.182038834951456 0.2346903840309689 0.604438060013534 2.5783097591374724 2.178528878890925 0.7809766783412604 0.2977904248922783 1.0 1.0 0.0022717439932715 0.0004730993907641 +Neoplasm of the large intestine 24 47 2.168773253730484 0.030099902774074 14.990291262135925 43.70145631067961 -0.3846400133306127 0.5454044650659606 6.628850074728242 4.835216465424141 1.0050611011761914 0.3366240827259003 0.3535804343497586 0.5907159409401193 0.0756775204280773 4.251465468562368e-05 +Elevated urinary carboxylic acid 1 8 2.116421176762593 0.0343090025677026 2.145631067961165 6.854368932038835 -0.371724223489112 0.4248536815667606 1.459204245106796 1.2877900615123286 1.058591796269418 0.2877928844597015 0.0539630923046902 0.1073692926764015 0.0323840811666381 0.1125747569923622 +Autoimmune hemolytic anemia 5 9 2.116352615166546 0.0343148289393921 3.4902912621359223 9.016990291262136 -0.1842519454202277 0.5314036315478876 2.51450219216243 1.1771294151876055 0.8906380525330514 0.2917331848022949 1.0 1.0 0.3547863423381785 0.0013369974246366 +Abnormal muscle glycogen content 4 6 2.115160906329771 0.034416235629977 1.6966019417475728 4.512135922330097 0.3043369892913118 0.5468257743353838 1.251285981916172 0.9938394221699504 0.8529624348688617 0.30477178619368 1.0 1.0 0.2159896916124382 0.0105668672564949 +Abnormality of the pituitary gland 19 65 2.1124320457342503 0.0346494087982935 14.259708737864075 61.400485436893206 -0.1002797447332781 0.7077868077881709 7.077794340802815 6.228832095900011 0.6838680808453562 0.2992836290506009 0.5992321424203728 0.8462179957044783 0.1927950950158071 0.0069498726687038 +Autoimmune thrombocytopenia 5 8 2.109201097040413 0.0349272272746605 3.0558252427184467 8.62135922330097 -0.0570227617080535 0.5553818620485818 2.34609571323795 1.3410364406071484 0.8892502626526966 0.299970850125507 1.0 1.0 0.4559893986318888 0.0062616815035888 +Pituitary adenoma 6 12 2.1081136921351677 0.0350211563640101 3.320388349514563 11.643203883495143 0.1746875760715562 0.4661778247712407 2.329480096306377 1.8225601930966908 1.1510177222727556 0.3259225965805015 1.0 1.0 0.2229147983640583 0.0081853110588452 +Bilateral polymicrogyria 5 9 2.104070640151779 0.035372285480256 2.6189320388349513 8.305825242718447 -0.0448660199171584 0.6246358938706429 2.0031360910494262 1.1442829817293565 0.7120702164844465 0.2679983693308225 1.0 0.2473900535744361 0.0054543168641633 0.0137665493817408 +Cleft soft palate 27 62 2.100819252921313 0.0356568357126354 14.070388349514564 59.29368932038835 -0.0841231048387167 0.6761970338349651 7.345654342076159 3.931903239901028 0.7202309535052254 0.301153687087254 0.1296900098932465 0.1365184835783493 0.0455817784516504 0.0147941241100439 +Anophthalmia 4 8 2.0960107824158523 0.0360812344634047 2.861650485436894 9.395631067961164 0.4842375076047043 0.4992513937830266 1.7811813452413223 2.297377217063272 0.8357915391858239 0.2927718406240587 1.0 0.4064849903072076 0.382468938576878 0.5035819637571283 +Unusual fungal infection 6 11 2.094395784216133 0.036224738008225 2.6893203883495147 9.54368932038835 -0.0023066162421285 0.5742499417404393 2.2610210178108416 1.443274990982205 0.8415328355339042 0.2935680666695555 1.0 1.0 0.0440381918347023 0.0203628052401783 +Lissencephaly 19 56 2.0906647226031425 0.0365581294376067 11.99757281553398 53.101941747572816 0.5259220304939708 0.6194937069774594 4.769695389516564 5.996301134664397 0.6834848227329613 0.3335889152857388 0.4737269668476327 0.1408443947007736 0.0004825725941644 0.0165418804982065 +Abnormal t cell morphology 8 17 2.0887324921062347 0.0367318102753064 3.754854368932039 14.048543689320388 -0.0196547426962508 0.5904668188634875 2.5977213181464935 2.733746818117393 0.7824732466905501 0.28200755051941 1.0 1.0 0.0031662335838307 0.0150707717640174 +Large for gestational age 3 7 2.08726597718636 0.0368640984399506 2.7815533980582523 8.388349514563107 0.0632770466831692 0.5874491218187148 1.8684528448843485 1.5468917140275038 0.8216368851097278 0.2910060687719157 1.0 0.2685126379615966 0.5524281428970466 0.4808786474245576 +Autoimmune antibody positivity 7 11 2.0769179136828497 0.0378091360948427 3.4757281553398056 9.968446601941748 0.0066447462766394 0.5617941238228003 2.757495205724867 1.471896773291632 0.8776172463469344 0.2952396876231036 1.0 1.0 0.1617118829485157 0.0553856285019619 +Decreased specific antibody response to vaccination 3 5 2.0760830164497706 0.0378862736528737 1.3810679611650485 3.4927184466019416 0.4340850364055848 0.5354054904507262 1.0985121558482311 0.8962951730498935 0.8743629772977977 0.3171068631424719 1.0 1.0 0.0025675639060761 0.0019884945269669 +Distal arthrogryposis 1 5 2.0701577325174827 0.038437575961955 1.3883495145631068 4.733009708737864 0.1519686049648115 0.4244431219015394 0.905570781853283 0.6908399769064817 1.0957375224178318 0.2710224797540735 0.0451714964804377 0.0903020002145616 0.0227865880642579 0.0817606313480972 +Recurrent sinusitis 3 5 2.060732699776618 0.0393285481847245 1.8203883495145632 5.065533980582524 0.1394784458399675 0.5166478982984708 1.4062177615412113 1.385807554800596 0.9567780157824576 0.2991860115674145 0.1215010987245368 0.2329741481650856 0.1448451451272836 0.0446088038944012 +Abnormal circulating ige level 3 5 2.0584290175683 0.0395489686194205 1.6820388349514563 5.026699029126213 0.1394570318460624 0.5181582224100653 1.371827396671621 1.2872661543499773 0.9538080926284928 0.3072697619305176 1.0 1.0 0.4002719515071794 0.0790607116166092 +Abnormality of the pulmonary veins 1 8 2.054217595432838 0.0399546361491367 1.2135922330097086 6.669902912621359 0.9535622979003926 0.3793496965363341 1.175399006302687 0.7806936113776552 0.7920022166500139 0.2937792263138297 0.0112335965286378 0.0426903814680922 0.2051784324027348 0.5122684088981724 +Abdominal obesity 1 6 2.0531226283553536 0.0400606858562708 2.058252427184466 4.798543689320389 -0.1964127770689827 0.6149333180168268 1.3974681872367505 1.3937091029426565 0.7487383445423474 0.2843593916766038 1.0 1.0 0.0553069748090555 0.1807018090276839 +Sarcoma 23 62 2.0484384979586805 0.0405170525695002 13.49271844660194 59.24757281553398 0.2024053329324482 0.5878401261352646 7.66928341789692 5.604858236953758 0.9869836607136444 0.3372231979111714 0.1220063103614903 0.1259148038007111 0.0384735020044066 1.7180149292014455e-05 +Abnormal circulating fatty acid anion concentration 2 14 2.0410405772143263 0.0412467940039871 3.4684466019417477 13.439320388349516 0.6959006280700144 0.4066366331458161 2.303748425990877 1.289881278600975 0.9955896787866196 0.2877623152669635 0.0045302650272878 0.0179304062363867 0.0150601402708497 0.088385561156941 +Adenocarcinoma of the colon 10 21 2.039742278352163 0.0413760016021835 9.50485436893204 20.58009708737864 -0.5385965908043259 0.4099332106587272 4.098007534825994 1.3513359051095024 1.3067136508964234 0.352270731481182 0.1215010987245368 0.2329741481650856 0.0004806947328874 3.828861199610836e-05 +Tapered finger 15 41 2.0382918497011397 0.0415207544866615 7.145631067961165 36.64320388349515 0.3950131100551636 0.6154126812135184 4.179022431771379 3.671773390640813 0.7440142028155114 0.3137206584133796 0.0108633849741065 0.002479231532576 0.0332010767014309 0.02302497178709 +Decreased circulating total igm 4 9 2.0306986370399813 0.0422855747049761 2.3033980582524274 8.182038834951456 0.3362927047737233 0.5303294556726676 1.899843659075206 1.6095490891353723 0.8660766705841132 0.3067292557005907 1.0 1.0 0.1203326107508497 0.0062616815035888 +Colitis 5 11 2.004854076119213 0.0449786494801429 3.4927184466019416 9.419902912621358 -0.1141014746794279 0.5851767175963839 2.4350685061134416 1.5283381387318045 0.8222939627592047 0.2937826320661567 1.0 1.0 0.6134016456847204 0.1190174178925116 +Abnormal circulating igm level 8 18 1.9728943814866997 0.048507596891993 3.682038834951456 14.9126213592233 0.1129875075186442 0.6415415348216943 2.6591785939662556 2.6184809800796582 0.7390331566929969 0.2893022470651504 1.0 1.0 0.0031662335838307 0.000798592209508 +Fair hair 2 5 1.9717391229794925 0.0486393950354853 1.4174757281553398 3.9223300970873782 0.1756626214879824 0.6211380157027715 1.1062424096138934 0.6261195082480088 0.7676554732091304 0.299093514097773 1.0 0.0988756314725496 0.2348471946143729 0.0968157430558884 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c63890001dcd175468773d11afcac5652fec5cb4 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 4613, + "title": "Average number of proteins per term", + "value": 24.61846954259701 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ffba4c283c8b513eea8b0b5853362defbdf2d484 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2602d8f3e15f7be7b626cb3a5fe3dd7122f2f4c7 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1342 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Impaired antigen specific response 0.7573439438723764 2.5968747331232853 0.0094076225912282 1.0 0.8518050485329919 9 P00813,Q9BV10,Q14790,P17812,P50851,P49327 6 +Abnormal b cell morphology 0.7131032268117059 2.562026068669746 0.0104063507185356 1.0 0.8518050485329919 13 Q00653,P00813,Q9BV10,P17812,Q13432,P49327 6 +Stereotypy 0.4220435437212443 2.5428296907280616 0.0109958810501418 1.0 0.8518050485329919 73 Q05639,Q03164,Q2M389,Q7Z6Z7,Q9BXJ9,Q06787,Q96F86,Q9BPU6,Q96N67,P26196,P67870,Q9BTW9,Q08209,Q01105,Q6IA86,P10589,O43776,Q08J23,Q05086,O14646,Q96C86,Q9NUQ7,Q14738,Q9UBB6,Q13501 25 +Megaloblastic anemia 0.7774134530185147 2.5323944442811475 0.011328647290119 1.0 0.8518050485329919 8 P41440,P11172,P00492,Q99707,P00374 5 +Macrocytic anemia 0.5980620934992512 2.5314187957165 0.0113602118743569 1.0 0.8518050485329919 37 P11586,P41440,P60866,P11172,Q9P2J5,P62081,P00492,Q99707,P62847,P08708,O00429,P62854,P00374,P42766,P39019,P22314,P62899 17 +Decreased circulating level of specific antibody 0.8054578378000865 2.510429170418429 0.012058451007729 1.0 0.8518050485329919 7 P00813,Q9BV10,Q14790,P17812,P49327 5 +Congenital sensorineural hearing impairment 0.7644070877117768 2.471017558006237 0.0134729203593777 1.0 0.8518050485329919 8 Q16740 1 +Fatigable weakness of skeletal muscles 0.7874605726895644 2.428784623516377 0.0151495288514249 1.0 0.8518050485329919 7 P11310 1 +Short middle phalanx of finger 0.8952513467616398 2.3971686457707424 0.0165223172180166 1.0 0.8518050485329919 4 Q03164 1 +Abnormal t cell subset distribution 0.6765799748299239 2.3672521449354984 0.0179207189711192 1.0 0.8518050485329919 13 P00491,Q14790,Q96BN8,P17812,Q13432,P49327,O95394 7 +Abnormal scapula morphology 0.4297268197674916 2.362560421576717 0.0181491826500379 1.0 0.8518050485329919 53 P60866,Q14331,Q14999,P62081,Q9Y487,P62847,O00429,P08708,Q06210,P62854,O43318,P42766,O15357,Q9Y5L0,Q08AM6,Q06124,P62899,Q8TD16,Q13501 19 +Abnormal middle phalanx morphology of the hand 0.7655128583631533 2.328173284604925 0.0199029041567144 1.0 0.8518050485329919 7 Q03164 1 +Patchy changes of bone mineral density 0.8643388134633528 2.26953924571752 0.0232355534353208 1.0 0.8518050485329919 4 Q15813,Q13126 2 +B lymphocytopenia 0.6592768641523697 2.2651639125018046 0.0235026227734764 1.0 0.8518050485329919 11 Q00653,Q13432,P00813,Q9BV10 4 +Focal non motor seizure 0.6578594000919032 2.255596580857057 0.0240959075479985 1.0 0.8518050485329919 10 Q01105,Q05639,P67870,P42356,Q08209 5 +Abnormality of the menstrual cycle 0.3738417821303754 2.239640627179974 0.0251142629388567 1.0 0.8518050485329919 57 P49770,Q16740,O00170,Q6W2J9,O00429,P31751,Q13144,Q9BUK6,Q06787,P40763,Q3SYG4,P40818 12 +Cessation of head growth 0.7458691906005928 2.237152751779888 0.025276358198377 1.0 0.8518050485329919 7 P49770,Q05086,Q9Y263 3 +Decreased plasma carnitine 0.6522274506008294 2.235073296124966 0.0254125371816829 1.0 0.8518050485329919 13 P11310,O43772 2 +Abnormal cd4 cd8 ratio 0.7749312295077823 2.233388361598842 0.0255233450079905 1.0 0.8518050485329919 6 Q13432,O95394,Q14790,P17812 4 +Abnormal morphology of the limbic system 0.6515286384812649 2.2312533884736867 0.025664349323609 1.0 0.8518050485329919 13 Q01105,Q05639,Q9BPU6,Q9UID3,P10589,P67870,Q08209 7 +Deep plantar creases 0.8131173345439786 2.2258814642055067 0.0260221222458867 1.0 0.8518050485329919 5 Q9Y487 1 +Recurrent sinopulmonary infections 0.7092219567591864 2.2057482056250115 0.0274016346304599 1.0 0.8518050485329919 8 Q9Y487,P57076,Q14790 3 +Nonprogressive 0.7338433109359443 2.18098064793064 0.0291848478760139 1.0 0.8518050485329919 7 Q69YN2,Q9NQZ5,Q06210 3 +Abnormal circulating iga level 0.6359770630123585 2.176452220323315 0.029521462676147 1.0 0.8518050485329919 17 Q00653,P00813,Q9BV10,Q14790,Q96BN8,Q9Y5L0,P50851,P49327 8 +Neoplasm of the large intestine 0.4697706478668957 2.168773253730484 0.030099902774074 1.0 0.8518050485329919 47 P60866,P54277,P42771,O96017,P62081,O60566,P62847,O43684,P08708,P62854,P42766,P39019,O43683,P28340,Q15645,Q13043,O14965,P20585,P52701,Q9UPY3,P62899,Q07864,P46783,Q9Y620 24 +Increased circulating acth level 0.83250990910375 2.1363146724620927 0.0326537737358521 1.0 0.8518050485329919 4 Q9UER7,P40818 2 +Elevated urinary carboxylic acid 0.6909938543233329 2.116421176762593 0.0343090025677026 1.0 0.8518050485329919 8 P11310 1 +Autoimmune hemolytic anemia 0.6615776591800995 2.116352615166546 0.0343148289393921 1.0 0.8518050485329919 9 P00813,P50851,P49327,Q969U7,P40763 5 +Abnormal muscle glycogen content 0.7486604564787901 2.115160906329771 0.034416235629977 1.0 0.8518050485329919 6 Q9BUK6,Q93100,P13807,P08237 4 +Abnormality of the pituitary gland 0.3745751171690591 2.1124320457342503 0.0346494087982935 1.0 0.8518050485329919 65 P60866,Q03164,O00170,P54277,Q7Z392,Q9BUK6,Q15813,Q96IJ6,Q06787,Q00653,O14802,P48735,P40818,Q4J6C6,P52701,P57081,Q14746,Q07864,P42356 19 +Autoimmune thrombocytopenia 0.6895278823066383 2.109201097040413 0.0349272272746605 1.0 0.8518050485329919 8 Q00653,P00813,P50851,P49327,P40763 5 +Pituitary adenoma 0.6298021891879156 2.1081136921351673 0.0350211563640101 1.0 0.8518050485329919 12 P60866,O00170,P54277,P48735,P52701,P40818 6 +Bilateral polymicrogyria 0.659194329467265 2.104070640151779 0.035372285480256 1.0 0.8518050485329919 9 Q01105,Q05639,P67870,P42356,Q08209 5 +Cleft soft palate 0.3694433953118867 2.100819252921313 0.0356568357126354 1.0 0.8518050485329919 62 P60866,Q9C0B1,Q15813,Q6PGP7,Q92796,O43505,Q9Y617,P62081,Q15392,O14802,P62847,Q15436,P08708,P62854,O43318,Q9Y4X0,P42766,P39019,Q13618,P36871,P62899,Q6W2J9,Q15058,Q93008,P62266,P46783,P78318 27 +Anophthalmia 0.6868524909296897 2.0960107824158523 0.0360812344634047 1.0 0.8518050485329919 8 Q6W2J9,Q96N67,O75569,O43505 4 +Unusual fungal infection 0.6276921409995494 2.094395784216133 0.036224738008225 1.0 0.8518050485329919 11 Q00653,P00813,Q9Y5L0,O95394,P40763,P40818 6 +Lissencephaly 0.3725615768392412 2.0906647226031425 0.0365581294376067 1.0 0.8518050485329919 56 Q00535,Q9NPF4,P42695,Q9C0B1,Q15392,Q9Y487,O43776,Q9BSJ2,Q08AM6,P42356,P57081,Q13535,Q9BV10,P43034,Q15058,Q00534,Q2VPK5,Q14204,Q15042 19 +Abnormal t cell morphology 0.6206494179535305 2.0887324921062347 0.0367318102753064 1.0 0.8518050485329919 17 P00491,P00813,Q14790,Q96BN8,P17812,Q13432,P49327,O95394 8 +Large for gestational age 0.713938257446884 2.08726597718636 0.0368640984399506 1.0 0.8518050485329919 7 Q8NCE2,O00330,P31751 3 +Autoimmune antibody positivity 0.6244899628072228 2.0769179136828497 0.0378091360948427 1.0 0.8518050485329919 11 Q00653,P00813,P53621,Q9Y5L0,P49327,P22314,O95394 7 +Decreased specific antibody response to vaccination 0.7787204827660371 2.0760830164497706 0.0378862736528737 1.0 0.8518050485329919 5 Q9BV10,Q14790,P17812 3 +Distal arthrogryposis 0.777370647644388 2.0701577325174827 0.038437575961955 1.0 0.8518050485329919 5 P11310 1 +Brain neoplasm 0.8160283687055077 2.0666226593214567 0.0387697239568149 1.0 0.8518050485329919 4 P28340,P21359 2 +Recurrent sinusitis 0.775225164623334 2.060732699776618 0.0393285481847245 1.0 0.8518050485329919 5 Q00653,Q13432,P57076 3 +Abnormal circulating ige level 0.7747010648874292 2.0584290175683 0.0395489686194205 1.0 0.8518050485329919 5 P00813,P40763,P49327 3 +Abnormality of the pulmonary veins 0.678399030712337 2.054217595432838 0.0399546361491367 1.0 0.8518050485329919 8 Q15392 1 +Abdominal obesity 0.7350052438882015 2.0531226283553536 0.0400606858562708 1.0 0.8518050485329919 6 P40818 1 +Sarcoma 0.3651265904957027 2.0484384979586805 0.0405170525695002 1.0 0.8518050485329919 62 P60866,P42771,O96017,P62081,O75874,Q15392,O60566,P62847,P08708,P48735,Q13126,P62854,P42766,P21359,Q15645,O14965,P49327,Q06124,P52701,P62899,Q01844,Q9Y620,Q13501 23 +Abnormal circulating fatty acid anion concentration 0.6162581307899808 2.0410405772143263 0.0412467940039871 1.0 0.8518050485329919 14 P11310,O43772 2 +Adenocarcinoma of the colon 0.6035571641437208 2.039742278352163 0.0413760016021835 1.0 0.8518050485329919 21 P28340,P62081,P60866,P62847,P08708,P62854,Q07864,P42766,P39019,P62899 10 +Tapered finger 0.503519199998614 2.0382918497011393 0.0415207544866615 1.0 0.8518050485329919 41 P53618,Q03164,Q9H4L7,Q9BPU6,O00170,O15357,P10589,P26196,Q7Z6Z7,P27635,Q15555,Q9Y4X0,Q08AM6,Q8IWS0,P28482 15 +Decreased circulating total igm 0.6450170027424056 2.0306986370399813 0.0422855747049761 1.0 0.8518050485329919 9 Q00653,P49327,P00813,Q14790 4 +Myeloid leukemia 0.8017398309027715 2.005824720456814 0.0448749522057472 1.0 0.8598080594412354 4 P21359,P22681 2 +Juvenile myelomonocytic leukemia 0.8017398309027712 2.0058247204568116 0.0448749522057474 1.0 0.8598080594412354 4 P21359,P22681 2 +Colitis 0.6113434443595573 2.004854076119213 0.0449786494801429 1.0 0.8598080594412354 11 O43318,P50851,Q6PGP7,Q15477,P49327 5 +Decreased cd4 cd8 ratio 0.7972622160417276 1.9867014866641977 0.0469554869850392 1.0 0.8598080594412354 4 Q14790,P17812 2 +Abnormal circulating igm level 0.5989198460892647 1.9728943814866993 0.048507596891993 1.0 0.8598080594412354 18 Q00653,P00813,Q9BV10,Q14790,Q96BN8,Q9Y5L0,P50851,P49327 8 +Fair hair 0.7550631920005427 1.9717391229794925 0.0486393950354853 1.0 0.8598080594412354 5 Q05086,Q8IWV7 2 +Abnormal parietal bone morphology 0.7936081242532781 1.9710707150029152 0.0487157878586606 1.0 0.8598080594412354 4 Q08AM6,O14802,Q06124 3 +Increased proteinogenic amino acid level in urine 0.6029215746644111 1.9584334186344197 0.0501791766099573 1.0 0.8612078758318727 11 P11310 1 +Polyphagia 0.6309686272884061 1.957477596186422 0.0502913432970668 1.0 0.8612078758318727 9 Q05086,Q3SYG4,P42858 3 +Happy demeanor 0.7899015948601 1.9551931815179733 0.0505602730739873 1.0 0.8612078758318727 4 Q05086 1 +T cell lymphoma 0.7884059941601371 1.9487801711395203 0.0513216827470912 1.0 0.8612078758318727 4 P49327,Q07864 2 +Abnormal proportion of cd4 positive t cells 0.6845313296609404 1.9471732287441037 0.0515139700946951 1.0 0.8612078758318727 7 Q13432,P49327,Q96BN8 3 +Abnormal erythrocyte enzyme level 0.5904657704868009 1.946630694567268 0.0515790259452089 1.0 0.8612078758318727 20 P62081,P60866,P00813,P62847,P08708,P62854,P42766,P39019,P62899 9 +Abdominal wall muscle weakness 0.7490500873232944 1.945052482259258 0.0517686620936044 1.0 0.8612078758318727 5 P21359,P36507,Q14331 3 +Rickets 0.6828095888794871 1.938912118368148 0.0525120400899321 1.0 0.8612078758318727 7 Q9Y617,Q01968,Q9NSD9 3 +Focal emotional seizure 0.6256880335289805 1.929825506026005 0.0536284620445823 1.0 0.8612078758318727 9 Q01105,Q05639,Q08209,P67870 4 +Ankyloblepharon 0.7426183043612011 1.91643569323914 0.0553096612164401 1.0 0.876781674197382 5 Q6W2J9,P18074,O75569 3 +Recurrent herpes 0.7006140750780223 1.8951653115283071 0.0580705041972566 1.0 0.8908387767009742 6 Q13432,Q14790 2 +Increased muscle glycogen content 0.7749226575819345 1.8908025079615296 0.058650712281143 1.0 0.8929232203066431 4 Q9BUK6,Q93100 2 +Urticaria 0.6144512759031004 1.8707558836827265 0.0613789250050764 1.0 0.9074055328389852 9 Q9Y5L0,P18074,P22681 3 +Increased circulating iga level 0.731724012455299 1.867797728739088 0.061790270174683 1.0 0.9074055328389852 5 Q9Y5L0,P49327,Q96BN8 3 +Recurrent viral infections 0.5823836698259434 1.8667520389002952 0.0619362229473074 1.0 0.9074055328389852 17 Q00653,P00491,P33991,P00813,Q14790,Q13043,P17812,Q13432,Q7Z2Z2,O95394 10 +Abnormality of small intestinal villus morphology 0.6944413148912004 1.8665644098674905 0.061962441544392 1.0 0.9074055328389852 6 Q9H3U1,P34949,P50851,Q15477 4 +Oromandibular dystonia 0.7647982321077633 1.8470808199510669 0.0647354278274321 1.0 0.9299186853430752 4 Q9H269 1 +Neoplasm of the colon 0.4851144521498827 1.8344897977939385 0.0665813208447305 1.0 0.9356423669459488 40 P28340,P60866,P62081,O60566,Q15645,P54277,P62847,P08708,P62854,Q07864,P42771,P42766,P20585,P46783,P39019,P52701,O96017,P62899 18 +Oculogyric crisis 0.5801905687026484 1.8321930693586863 0.0669226610775752 1.0 0.9356423669459488 11 Q01105,Q05639,O00429,P67870,Q08209 5 +Ventricular fibrillation 0.7229617202204499 1.8285305818991908 0.0674699602487975 1.0 0.9356423669459488 5 Q99996 1 +Gastrointestinal carcinoma 0.5292375067884506 1.8239437303160608 0.0681605795667947 1.0 0.9356423669459488 32 P60866,O96017,P62081,O60566,P62847,P08708,P62854,P42766,P39019,O43683,P28340,Q13043,O14965,P43246,P52701,P62899,Q07864,P46783,Q9Y620 19 +Adenocarcinoma of the intestines 0.5629448414308592 1.8237264054164375 0.068193444786331 1.0 0.9356423669459488 23 P28340,P62081,P60866,Q13043,P62847,P08708,P62854,P43246,Q07864,P42766,P46783,P39019,P62899 13 +Congenital contracture 0.4763554389292845 1.8178147499627528 0.0690924514548325 1.0 0.9356423669459488 41 P11310,Q15392,Q00535,P50570,Q99986,Q06210,Q15058,O00330,P18074,Q8TD16,P40763,Q96AY3,P42356,Q9BTW9,Q08209 15 +Abnormality of the hypothalamus pituitary axis 0.3566179377946896 1.8126378852277616 0.0698876905408669 1.0 0.9356423669459488 70 P60866,Q03164,O00170,P54277,Q7Z392,Q9BUK6,Q15813,Q96IJ6,Q06787,Q00653,O14802,P48735,P40818,Q4J6C6,P52701,P57081,Q14746,Q07864,P42356 19 +Oligomenorrhea 0.656332481444071 1.8110927624786828 0.0701264936816929 1.0 0.9356423669459488 7 P31751,P40818 2 +Bloody diarrhea 0.7560950995582327 1.809373337379136 0.0703930224935502 1.0 0.9356423669459488 4 Q15477 1 +Anemia of inadequate production 0.3517531705350998 1.8022790912645377 0.0715015064531805 1.0 0.9356423669459488 67 P41440,P60866,P11172,Q9P2J5,Q9UER7,P22314,P62081,P04075,P00492,P62847,O00429,P08708,P62854,P42766,P39019,Q99707,P00374,P49327,P62899,P11586,Q9Y285 21 +Abnormality of the thenar eminence 0.5680386759662097 1.8003304272997986 0.0718084791643864 1.0 0.9356423669459488 19 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Deeply set eye 0.3605645394566385 1.7962813763032868 0.0724497782407764 1.0 0.9356423669459488 74 Q05639,Q7Z6Z7,Q15813,P18074,Q16512,Q06787,O60701,O14802,Q9BPU6,O00429,Q8IWS0,Q9BTW9,P40763,Q9NSD9,P21359,Q92917,P63241,Q05086,A1X283,P28482,Q96C86,Q14738,P49589,O75179,Q15042,Q9Y285 26 +Postaxial foot polydactyly 0.6001152516763048 1.7949616193589877 0.0726598151750108 1.0 0.9356423669459488 9 Q3SYG4 1 +Abnormality of the 5th toe 0.6001152516763048 1.7949616193589877 0.0726598151750108 1.0 0.9356423669459488 9 Q3SYG4 1 +Abnormal left ventricular outflow tract morphology 0.7146698536002338 1.7912544930289431 0.0732524651400838 1.0 0.9356423669459488 5 O43684,O60566,Q06124,Q15645 4 +Subvalvular aortic stenosis 0.7146698536002338 1.7912544930289431 0.0732524651400838 1.0 0.9356423669459488 5 O43684,O60566,Q06124,Q15645 4 +Neonatal hypoglycemia 0.5721806654569996 1.7889357936368864 0.0736251564652925 1.0 0.9356423669459488 10 O43772 1 +Adenomatous colonic polyposis 0.8993729471483995 1.7813479909990615 0.0748556190050648 1.0 0.9356423669459488 3 P28340,Q07864 2 +Clubbing 0.564299606650625 1.7779023139887853 0.0754199001219482 1.0 0.9356423669459488 19 Q9H4L7,Q9UID3,P57076,Q86TI2,P18074,P50851 6 +Exercise induced myalgia 0.5704519043715033 1.7777084071594726 0.0754517581842386 1.0 0.9356423669459488 11 P11310 1 +Panniculitis 0.592693155597365 1.7555403364963278 0.0791669274280795 1.0 0.9420173452973908 9 Q96BN8,Q9Y3Z3,P28070,P49327,Q969U7,P52732 6 +Unsteady gait 0.3335493667904229 1.7456008727320835 0.0808803305054615 1.0 0.9420173452973908 57 P49770,Q05639,Q96C86,Q7Z460,Q2TAL8,Q13144,Q14738,P42858,O00330,Q69YN2,Q08AM6,O60231,Q16512,Q08209,O75569 15 +Neonatal asphyxia 0.6684574282250674 1.7453918036665692 0.0809166914254837 1.0 0.9420173452973908 6 Q8NCE2,P51570,P49419 3 +Abnormal st segment 0.7390064605451341 1.7350187770357937 0.0827374793962092 1.0 0.9423901048264524 4 Q99996 1 +Webbed neck 0.4718919111983304 1.728397156787773 0.0839170448936039 1.0 0.944662516074238 40 P21359,P62081,P60866,Q03164,Q6W2J9,P36507,P62847,P08708,P62854,O43318,Q06124,P62899,P22681 13 +Cupped ribs 0.6133809670350082 1.7272447604015964 0.0841237152395193 1.0 0.944662516074238 8 P00813,O15357 2 +Anterior rib cupping 0.6593693844392303 1.7027305530651482 0.0886185043957992 1.0 0.9509801857720722 6 P00813 1 +Impaired horizontal smooth pursuit 0.7311827956989171 1.700845343063974 0.0889720322643081 1.0 0.9509801857720722 4 Q9NW08,P41440,P13639 3 +Decreased circulating igg level 0.5547601311091513 1.6981997750737092 0.0894700630013178 1.0 0.9509801857720722 16 Q00653,P00813,Q14790,P17812,P18074,P49327 6 +Abnormal vitamin b12 level 0.6934825588298913 1.6955186657798995 0.0899770723824981 1.0 0.9519031266285488 5 P41440,Q99707,P49327 3 +Erythroid hypoplasia 0.5488578017710863 1.695142148942868 0.0900484581724656 1.0 0.9519031266285488 20 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Onychomycosis 0.8763810092564865 1.6933844949719925 0.0903823042409071 1.0 0.9519031266285488 3 Q9Y5L0,P40818 2 +Malignant genitourinary tract tumor 0.5441359174556344 1.6910443843477705 0.0908283259831339 1.0 0.9544215666519292 22 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P52701,P62899 9 +Astrocytoma 0.5536200051714 1.6853204348304702 0.0919267652137425 1.0 0.9610744724247148 10 P21359,O75874,P48735,P42771,P20585,P52701 6 +Metaphyseal striations 0.6553214109132166 1.6836848116695156 0.0922425981709009 1.0 0.9610744724247148 6 Q13126 1 +Wide nasal ridge 0.7270948477149963 1.682958314701043 0.0923831613773185 1.0 0.9610744724247148 4 O14802 1 +Gastritis 0.6874813265610873 1.6682822708432656 0.0952597056900743 1.0 0.9610744724247148 5 P49327,Q6PGP7,P50851,Q15477 4 +Persistence of hemoglobin f 0.5404018541194343 1.6678018194936532 0.0953550745878382 1.0 0.9610744724247148 22 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Reticulocytopenia 0.5423878335379101 1.6671051444402292 0.0954934993882317 1.0 0.9610744724247148 21 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Decreased fertility in females 0.6001822116006396 1.6597961089446225 0.0969554767969191 1.0 0.9610744724247148 8 P57076,O00170 2 +Multiple lentigines 0.6491598105048271 1.6546448555989368 0.0979965590165965 1.0 0.9659361682554698 6 P36507,Q06124 2 +T lymphocytopenia 0.5731934525583333 1.6514307635445904 0.0986506474625148 1.0 0.9682456100948532 9 Q13432,P00813,P49327 3 +Ileus 0.7182137422464462 1.6440286961300727 0.1001702750139004 1.0 0.9767837515803888 4 Q01844 1 +Fractures of the long bones 0.7178630948331617 1.6424897650191388 0.1004885455413306 1.0 0.9767837515803888 4 Q13126,Q9BTW9 2 +Anteverted ears 0.7178591796708818 1.6424725812539689 0.1004921039074986 1.0 0.9767837515803888 4 Q6W2J9,P27635 2 +Freckling 0.5457706565373036 1.6373244481382525 0.1015626951840062 1.0 0.9767837515803888 13 P21359,P42771,O43318,P18074,P52701,Q06124 6 +Abnormality of the parathyroid morphology 0.644006815912895 1.6303142156114554 0.1030351046216766 1.0 0.9767837515803888 6 P21359,P48735 2 +Severe intrauterine growth retardation 0.8594616636076676 1.6283776348843129 0.1034448369214635 1.0 0.9767837515803888 3 Q15813 1 +Decreased circulating iga level 0.5435401813748386 1.6260452264949687 0.103940034661192 1.0 0.9767837515803888 11 Q00653,P00813,Q14790 3 +Neoplasm of the parathyroid gland 0.6776468294898466 1.6235438264074828 0.1044732025363788 1.0 0.9767837515803888 5 P21359,P48735 2 +Parathyroid adenoma 0.6776468294898466 1.6235438264074828 0.1044732025363788 1.0 0.9767837515803888 5 P21359,P48735 2 +Stomach cancer 0.5425732246786049 1.6205689188305026 0.1051101225381536 1.0 0.9767837515803888 11 P60866,O60566,Q15645,O43684,P42771,P20585,O96017 7 +Generalized tonic seizure 0.539401287778602 1.6196699672067671 0.1053031909166855 1.0 0.9767837515803888 18 Q01105,Q05639,Q96N67,P43034,P27635,Q14746,P67870,Q9BTW9,Q08209 9 +Sloping forehead 0.37792283455133 1.6173148925689582 0.1058103262249074 1.0 0.9767837515803888 51 Q9NPF4,P42695,Q96KP1,Q9Y617,O60566,P47897,P08243,Q92917,Q15645,Q08J23,Q9BSJ2,Q13057,Q13535,P26640,Q15058,Q00534,Q15021,Q15003,O95630,P52732 20 +Increased sulfur amino acid level in urine 0.7103272625725119 1.6093831463463997 0.1075325882123747 1.0 0.9767837515803888 4 Q99707 1 +Abnormal c reactive protein level 0.6394112628936865 1.6085829889087575 0.1077075563591873 1.0 0.9767837515803888 6 P22314,Q9UHD2,P53621,Q96BN8 4 +Malignant hyperthermia 0.7096774193548304 1.6065253503283927 0.1081585296009086 1.0 0.9767837515803888 4 Q8NCE2,O95163,P50570 3 +Large basal ganglia 0.5370595980925927 1.6056197492512494 0.1083574834891725 1.0 0.9767837515803888 18 Q96C86,Q2M389,Q9NUQ7,Q9UBB6,Q96F86,Q13535 6 +Irregular menstruation 0.6137797902842131 1.602891179704198 0.1089586813581631 1.0 0.9767837515803888 7 Q3SYG4,O00170 2 +Macrogyria 0.6728870551963211 1.601846761362005 0.1091894996899958 1.0 0.9767837515803888 5 Q15392,O43505 2 +Chorioretinal dysplasia 0.7060721680280129 1.5906626446464682 0.1116855180302018 1.0 0.9767837515803888 4 P52732,O43505 2 +Large earlobe 0.6093191340147766 1.5808956992628098 0.1139018878501474 1.0 0.9767837515803888 7 O60701,Q15392,Q96N67 3 +Neonatal insulin dependent diabetes mellitus 0.7034678791176744 1.5791958377984092 0.1142911443649583 1.0 0.9767837515803888 4 O00330,P40763 2 +Renal agenesis 0.3294736822902558 1.576522327837914 0.1149054772433171 1.0 0.9767837515803888 56 P62081,P60866,Q15392,P42695,P62847,P08708,P62854,Q00534,Q2VPK5,Q06124,P62899,O75179 12 +Rhabdomyosarcoma 0.5335554729783306 1.5725184556145928 0.1158303624519423 1.0 0.9767837515803888 10 P21359,O60566,Q15645,O43684,P42771,O96017,Q9UPY3 7 +Neoplasm of striated muscle 0.5335554729783306 1.5725184556145928 0.1158303624519423 1.0 0.9767837515803888 10 P21359,O60566,Q15645,O43684,P42771,O96017,Q9UPY3 7 +Abnormal circulating igg level 0.5285341859755285 1.5709600232581655 0.1161919348790077 1.0 0.9767837515803888 20 Q00653,P00813,Q9BV10,Q14790,P17812,P18074,P50851,P49327 8 +Recurrent hand flapping 0.6650643014856941 1.5661290081452646 0.1173184182650264 1.0 0.9767837515803888 5 Q05086 1 +Biconcave vertebral bodies 0.6288210259094202 1.558394263733856 0.1191398155933969 1.0 0.9786645343038104 6 Q9NR45,O00170,P40818 3 +Poor speech 0.3635236569171431 1.5580123503904468 0.1192303204592979 1.0 0.9786645343038104 92 Q05639,Q9NX46,Q2M389,Q7Z392,Q9P0J0,O60826,P27708,Q92796,Q16512,Q96F86,Q14353,Q96N67,Q9Y487,P67870,Q9BTW9,Q08209,Q01105,Q9Y4P8,Q08J23,P04350,Q05086,Q9UET6,Q96CU9,Q96C86,Q9NUQ7,Q15058,Q14738,Q93008,Q9UBB6,Q13501,Q14204 31 +Morphological abnormality of the vestibule of the inner ear 0.8392137265748403 1.550325796285134 0.1210633387730779 1.0 0.9836281695931668 3 P22681 1 +Decreased circulating igg subclass level 0.8384297184233238 1.5472988085720771 0.1217912089160249 1.0 0.9836281695931668 3 P17812 1 +Enlarged thorax 0.5288588734335623 1.5423891980078492 0.1229790449186809 1.0 0.9836281695931668 15 Q92917,Q6W2J9,Q99575,Q06124,P28482,Q14999,P22681 7 +Redundant neck skin 0.5523969653932993 1.53964606491428 0.123646650411239 1.0 0.9836281695931668 9 Q9Y487,Q08AM6 2 +Panhypogammaglobulinemia 0.6590655855743208 1.5386937273720915 0.123879084395853 1.0 0.9836281695931668 5 P26639,P18074,Q15477 3 +Abnormal breath sound 0.5284766858210077 1.5385106339262895 0.1239238104844742 1.0 0.9836281695931668 12 Q86TI2,P57076,P38935 3 +Normochromic anemia 0.5141692186462568 1.531466711474529 0.1256540874993268 1.0 0.9857862340720998 24 P62081,P60866,P04075,P62847,P08708,P62854,P42766,P39019,P62899 9 +Abnormality of the nasal septum 0.6229278881054621 1.5304040299333108 0.1259167520917978 1.0 0.9861697409158974 6 P21359 1 +Hypoketotic hypoglycemia 0.5719570971364927 1.5146031623057594 0.1298729308910773 1.0 0.9880751233645904 8 O43772 1 +Abnormal cell proliferation 0.6888013288705569 1.5145000419212848 0.1298990632004888 1.0 0.9880751233645904 4 O95394,P17812 2 +Pulmonary insufficiency 0.6189322151017627 1.5114029548863288 0.1306858169697327 1.0 0.9915356475022646 6 Q86TI2 1 +Antinuclear antibody positivity 0.6872759856630726 1.5077610317789174 0.1316156988839587 1.0 0.9947809730098908 4 Q9Y5L0,P53621,P49327 3 +Abnormality of the musculature of the hand 0.46093599859515 1.5064031350638567 0.1319637163925358 1.0 0.9947809730098908 37 P62081,P60866,Q7Z392,P62847,O60568,P08708,P62854,O43318,P42766,Q8TD16,Q13501,P39019,Q96IJ6,P62899 14 +Non hodgkin lymphoma 0.5218502875261422 1.5005236780078666 0.1334788047750981 1.0 0.9953651549675712 12 P00813,Q07864,P42771,P49327,P52701 5 +Cachexia 0.5189682196919377 1.491257994845344 0.1358937726154567 1.0 0.9953651549675712 17 P11310,Q01844,Q13535 3 +Bone fracture 0.5909174226775034 1.489881827202488 0.1362553106533623 1.0 0.9953651549675712 7 Q9BTW9,Q13501,Q13126 3 +Decreased proportion of cd4 positive helper t cells 0.6479438438195484 1.487733794371571 0.1368211115663182 1.0 0.9953651549675712 5 Q13432,P49327 2 +Abnormal circulating progesterone level 0.6132910440114381 1.484547356580031 0.1376637695359441 1.0 0.9953651549675712 6 P49770,Q14232,Q13144 3 +Decreased circulating progesterone 0.6132910440114381 1.484547356580031 0.1376637695359441 1.0 0.9953651549675712 6 P49770,Q14232,Q13144 3 +Hypsarrhythmia 0.3164707119196308 1.4835990113940956 0.1379153318279655 1.0 0.9956235144325588 60 Q05639,O60701,P21359,Q96N67,Q9Y263,Q96C86,Q2M389,Q9NUQ7,Q08J23,Q08209,P08243,Q9UBB6,P49419,Q96F86,Q9Y6D5 15 +Psychomotor deterioration 0.5408008482788321 1.4770441606949485 0.1396638000823353 1.0 0.9998999816084148 9 Q03164 1 +Osteosarcoma 0.5004346220518459 1.4761058657875954 0.1399154744614357 1.0 0.9998999816084148 26 P62081,P60866,P62847,P08708,P62854,Q13126,P42771,P42766,Q13501,P39019,O96017,P62899 12 +Neutropenia in presence of anti neutropil antibodies 0.5876065987652909 1.4734652865030735 0.1406256174477573 1.0 0.9998999816084148 7 O95394,P40763,P49327 3 +Lower limb asymmetry 0.6445537238317933 1.472178371117625 0.1409727164742551 1.0 0.9998999816084148 5 P07437,P28482,Q15555 3 +Hand clenching 0.5157757578771384 1.4720169077644891 0.1410163118515743 1.0 0.9998999816084148 10 Q03001,Q6W2J9,Q8TD16,Q00535 4 +Thyroid adenoma 0.6791146209912763 1.4716744933287165 0.1411087986184864 1.0 0.9998999816084148 4 P20585 1 +Pure red cell aplasia 0.510448195529676 1.469488325546826 0.14170038603284 1.0 1.0 21 P62081,P60866,P00491,P62847,P08708,P62854,P42766,P39019,P62899 9 +Perisylvian polymicrogyria 0.6434152785789933 1.4669525861266088 0.142388953883271 1.0 1.0 5 P42356 1 +Acute kidney injury 0.676523297491029 1.4602070920917494 0.1442331667785716 1.0 1.0 4 P00492,P07741,P04075 3 +Ventricular tachycardia 0.5147669563430363 1.459860188091635 0.1443285027908776 1.0 1.0 12 O43772 1 +Cafe au lait spot 0.3779367589951204 1.4552846089618103 0.1455904857441261 1.0 1.0 49 P22681,P21359,Q9BPU6,O60566,Q15645,P26196,Q7Z6Z7,P36507,P42858,A1X283,Q8IWV7,P52701,Q15477,P28482,Q06124,O60333 16 +Abnormal female reproductive system physiology 0.3253564014162909 1.4476192202930105 0.1477235727832333 1.0 1.0 69 P49770,Q16740,O00170,Q6W2J9,O00429,P31751,Q13144,Q9BUK6,P49327,Q06787,P40763,Q3SYG4,P40818 13 +Narrow palpebral fissure 0.5112258315007812 1.4377824176784262 0.1504957995977398 1.0 1.0 14 O95394,P26196,Q03164,P27635 4 +Bilateral cryptorchidism 0.5096280837137507 1.4371775822910082 0.1506675411292009 1.0 1.0 10 P33992,P36543,P27635,Q07864,P48449,P78318 6 +Dysuria 0.5569620320803692 1.4370494813926435 0.1507039342300022 1.0 1.0 8 P08397,P07741,Q8N0X7,O00170 4 +Abnormality of the hypothenar eminence 0.6712125893968005 1.4366929518948577 0.1508052585220509 1.0 1.0 4 Q96IJ6 1 +Increased mean corpuscular volume 0.4990714876416277 1.4347808636098598 0.1513495526850974 1.0 1.0 24 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Irregular hyperpigmentation 0.3250639875937289 1.42833043947082 0.1531967703858345 1.0 1.0 70 Q7Z6Z7,Q9BUR4,Q15555,P18074,O60333,P22681,Q9H4L7,Q9BPU6,O60566,P36507,Q8IWV7,P21359,Q15645,P07437,A1X283,P52701,Q06124,P28482,P42858,Q15477 20 +Female infertility 0.6685486227023195 1.4248919556108104 0.1541884353551617 1.0 1.0 4 P57076 1 +Facial telangiectasia 0.6338211181497535 1.422875335035739 0.1547722975051959 1.0 1.0 5 Q9UER7 1 +Bruxism 0.5770226718722018 1.420916664270025 0.1553409878264924 1.0 1.0 7 O95352 1 +Abnormality of the hepatic vasculature 0.5069048665740514 1.4175931270156474 0.1563095879113443 1.0 1.0 11 Q9Y5L0,P34949,P22681 3 +Recurrent hypoglycemia 0.6321843907397006 1.4153499300407366 0.1569659223086619 1.0 1.0 5 Q16512,Q9BV10 2 +Bradycardia 0.5067704223424786 1.413898218780922 0.1573917890220961 1.0 1.0 12 O43772,O75880 2 +Atypical absence seizure 0.803720845462288 1.4130386720071169 0.15764435370811 1.0 1.0 3 Q05086 1 +Cardiac diverticulum 0.6316103973707604 1.4127104346604051 0.1577408822142194 1.0 1.0 5 P54277,P60866,P52701,P43246 4 +Cutaneous syndactyly of toes 0.6648275584081351 1.4084024596578002 0.1590119313162485 1.0 1.0 4 Q6W2J9,Q9H4L7 2 +Increased circulating igm level 0.504366510454244 1.4073331254435837 0.1593286311211734 1.0 1.0 10 Q9Y5L0,P49327,Q96BN8 3 +Limitation of knee mobility 0.6304355075562896 1.407307157370827 0.1593363278966335 1.0 1.0 5 Q9BPU6 1 +B cell lymphoma 0.5969752014814509 1.406706660100894 0.1595143900270452 1.0 1.0 6 P00813 1 +Eyelid myoclonus 0.5036587534237225 1.4033170458512814 0.1605223173677386 1.0 1.0 10 Q01105,Q05639,P00374,P67870,Q08209 5 +Short femur 0.5730914966853913 1.401375681160583 0.1611017605379818 1.0 1.0 7 Q9Y4X0,Q9BV10 2 +Hypergonadotropic hypogonadism 0.5046225886985373 1.4000090481523666 0.1615106089708582 1.0 1.0 15 Q16740,Q9NW08,O14802,P48449 4 +Secundum atrial septal defect 0.6286942736144325 1.3992979234241354 0.1617236621002407 1.0 1.0 5 P21359 1 +Postaxial hand polydactyly 0.5034775366365739 1.3980172683229035 0.1621078816760932 1.0 1.0 11 Q3SYG4 1 +Glioblastoma multiforme 0.5261674898927878 1.3978451514585033 0.162159572304948 1.0 1.0 9 P60866,O75874,P54277,P42771,P52701 5 +Decreased fertility in males 0.5026561442057181 1.3933246583058494 0.1635216373087749 1.0 1.0 11 P57076,O00170 2 +Abnormality of the alveolar ridges 0.5710466780346501 1.3912072407708374 0.164162592190296 1.0 1.0 7 Q08AM6,Q15392 2 +Blepharophimosis 0.3636453915163336 1.3892993590706098 0.1647417387192238 1.0 1.0 50 O60701,Q03164,Q9BPU6,Q92917,P26196,Q6W2J9,Q7Z6Z7,Q15555,P42858,P07437,Q8IWS0,P28482,Q13535 13 +Porokeratosis 0.6597315793475969 1.3858108788904664 0.1658046596094311 1.0 1.0 4 P53602,Q15126 2 +Abnormality of renal excretion 0.5921155471261215 1.3834829409096234 0.1665168344827794 1.0 1.0 6 O43772 1 +Chylothorax 0.6582444230702943 1.3792162683495046 0.1678280836355652 1.0 1.0 4 P22681,Q06124 2 +Decreased specific antibody response to protein vaccine 0.7949037910038199 1.3788842364742824 0.1679304491442046 1.0 1.0 3 P17812 1 +Axonal degeneration 0.5911251693553146 1.3787482987232853 0.1679723723103672 1.0 1.0 6 Q92734,P38935 2 +Abnormal renal vascular morphology 0.5905046478523961 1.375781530677908 0.1688892811838438 1.0 1.0 6 P21359,Q08AM6 2 +Skin rash 0.4933935692068605 1.3736095171553726 0.169562940715519 1.0 1.0 22 Q9H4L7,Q96BN8,P18074,P28070,P22681 5 +Abnormal serum insulin like growth factor 1 level 0.6562902122376693 1.3705495549435576 0.1705154174784793 1.0 1.0 4 Q9BV10,O00170 2 +Hyperhomocystinemia 0.7914193783895546 1.365385267084819 0.1721319919902317 1.0 1.0 3 Q99707 1 +Partial duplication of the phalanx of hand 0.4911319457937997 1.3594226840038983 0.1740126870277669 1.0 1.0 22 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Severe varicella zoster infection 0.7898456933238365 1.3592886156084336 0.1740551501013043 1.0 1.0 3 P17812 1 +Long foot 0.4963494941519846 1.3572842491023418 0.1746909100833482 1.0 1.0 11 P21359,P08243,O00170 3 +Glioma 0.4967261426876943 1.35523493646548 0.1753427170596979 1.0 1.0 16 P21359,P60866,O75874,P54277,P48735,P42771,P20585,P52701 8 +Abnormality of the ovary 0.3138020566388987 1.3540202203158913 0.1757299267831729 1.0 1.0 66 P49770,O00170,P54277,P42771,Q14232,Q06787,Q3SYG4,O75874,P48735,P40818,Q9BW83,P31751,Q13144,P20585,P49327,Q06124,P52701,P51570,Q01844 19 +Disinhibition 0.3360982042728849 1.3499643506543202 0.1770274182713282 1.0 1.0 53 Q05639,Q2M389,Q8NC96,Q06787,Q96F86,Q9BPU6,Q96QK1,P26358,O75165,Q08209,Q6Y7W6,Q08J23,P49591,Q14203,Q04637,Q9H269,Q96C86,Q9NUQ7,Q9UHD2,P42858,Q9UBB6,Q13501,P15311 23 +Neoplasm of the skeletal system 0.4072502118233236 1.3468696738558086 0.1780222101091819 1.0 1.0 43 P60866,P54277,Q9Y3Z3,P42771,O96017,P62081,O75874,P62847,P08708,P48735,Q13126,P62854,P42766,P39019,P52701,Q06124,P62899,O15160,Q13501 19 +Aplasia hypoplasia of the ribs 0.4831337848661352 1.3467982025415175 0.1780452338061722 1.0 1.0 25 Q03164,Q9BV10,Q08AM6,O60826,Q14999,Q13535 6 +Thick hair 0.5842230729269968 1.3457380998832766 0.1783869944935876 1.0 1.0 6 Q9BUK6 1 +Biliary cirrhosis 0.5616032287429054 1.344217640460121 0.1788780188881076 1.0 1.0 7 Q9Y5L0,P21266,Q9UJW0,P48506 4 +Abnormal proportion of cd8 positive t cells 0.6496141514500828 1.3409351872887576 0.1799414965541736 1.0 1.0 4 P49327 1 +Anti thyroid peroxidase antibody positivity 0.7849572518480954 1.3403507516890327 0.1801313388048324 1.0 1.0 3 P00813 1 +Cupped ear 0.492946021498713 1.3310634892073214 0.1831681212395721 1.0 1.0 14 Q6W2J9,Q2TAL8,Q15392,P63241 4 +Abnormality of the fetal cardiovascular system 0.5781214734754173 1.316540821912694 0.1879925863785494 1.0 1.0 6 Q2TAL8,O60826 2 +Abnormal nasal mucosa morphology 0.6103976748636546 1.3150665940963833 0.1884875224630002 1.0 1.0 5 P57076 1 +Lymphopenia 0.460472041671211 1.3122301528427716 0.1894424909401721 1.0 1.0 31 Q00653,P11586,P00491,P00813,Q9BV10,Q9NRZ9,Q13043,P17812,Q13432,P50851,Q6PGP7,P49327,Q15477,Q13546,O95394,P28070 16 +Rhinitis 0.5328357582668368 1.3119142398605013 0.1895490723099866 1.0 1.0 8 Q9BV10,P57076 2 +Thin skin 0.4746012569333911 1.306759020859098 0.1912945666980388 1.0 1.0 26 Q9H4L7,O00170,Q13126,P18074,Q06787,Q9Y6D5,P40818 7 +Exertional dyspnea 0.486514319180179 1.3062098300048717 0.1914812108550116 1.0 1.0 19 P11310,Q6W2J9,Q86TI2 3 +Brittle hair 0.4880918638113566 1.304010294213969 0.192230072513595 1.0 1.0 16 Q9Y487,P26639,P36507,P49589,P62266,P18074,Q15477,Q6PGP7 8 +Generalized hyperreflexia 0.6076454605188131 1.3023898193033578 0.192783161038414 1.0 1.0 5 P26639,P18074 2 +Abnormality of the musculature of the upper limbs 0.3234619184526997 1.301790042065538 0.1929881688082302 1.0 1.0 77 P60866,Q14331,Q8NCE2,Q7Z392,Q96IJ6,Q14999,P62081,Q9Y487,P62847,P08708,Q06210,O00429,P62854,O43318,P42766,P39019,Q9Y5L0,P08397,Q06124,P62899,P46976,P50570,O60568,Q8TD16,Q13501 25 +Male infertility 0.5527684011454593 1.300227719577156 0.1935229327565997 1.0 1.0 7 P57076 1 +Broad alveolar ridges 0.6402333780385799 1.2993144240593135 0.1938360462607216 1.0 1.0 4 Q08AM6 1 +Spinal canal stenosis 0.5745097762350815 1.2992537580054089 0.1938568581280937 1.0 1.0 6 Q15813,O00170 2 +Macule 0.309126554733418 1.2970335335781789 0.1946196489859197 1.0 1.0 66 P22681,P21359,Q9H4L7,Q9BPU6,O60566,Q15645,Q7Z6Z7,Q9BUR4,P36507,P42858,P18074,A1X283,Q8IWV7,P52701,Q15477,P28482,Q06124,O60333 18 +Thin ribs 0.486574495433261 1.2937995957955974 0.1957346523558341 1.0 1.0 15 O14802,P50570,Q8NCE2,Q15813,Q08209,Q14999 6 +Chronic rhinitis 0.6386879221226032 1.292457611706176 0.1961987163060479 1.0 1.0 4 P57076 1 +St segment elevation 0.7715295877080457 1.2883477985264065 0.1976249213727681 1.0 1.0 3 Q99996 1 +Absent thumb 0.4716250944083067 1.2872733623048802 0.1979990246835896 1.0 1.0 26 P62081,P60866,P62847,P08708,P62854,P42766,Q08AM6,P46783,P39019,P62899 10 +Progressive extrapyramidal movement disorder 0.6037579648350357 1.28448351417699 0.1989728282627514 1.0 1.0 5 Q14353 1 +Hypouricemia 0.6037473912096506 1.284434811208925 0.1989898591901717 1.0 1.0 5 O96007,P00491 2 +Facial erythema 0.7699354153964459 1.282176578097992 0.1997807105287683 1.0 1.0 3 P40818 1 +Hodgkin lymphoma 0.5040547079566595 1.2779483824624722 0.2012676269872577 1.0 1.0 9 Q07864,P42771,P49327,O95394,P40763 5 +Abnormal paranasal sinus morphology 0.4741489274379291 1.275132939983627 0.2022621920708842 1.0 1.0 24 Q00653,P21359,P00813,P57076,Q13432,P50851,Q06787,P28070 8 +Abnormal circulating fatty acid concentration 0.4768728290583175 1.2700394155308343 0.2040705903863227 1.0 1.0 22 P11310,O43772 2 +Abnormality of vitamin d metabolism 0.4810409357025201 1.2697777377901045 0.2041638128297536 1.0 1.0 11 P46783,Q7Z2Z2,P41252,Q01968,Q9NSD9 5 +Selective tooth agenesis 0.5465704067235502 1.2693616051578984 0.2043121234875866 1.0 1.0 7 Q13535 1 +Aplasia hypoplasia of the skin 0.2950216640128049 1.2675149285653082 0.2049712290988647 1.0 1.0 57 P28340,Q9H4L7,Q15392,O14802,Q15126,O00170,Q9BUR4,Q13126,P18074,Q06787,Q9Y6D5,P40818 12 +Pancreatic hypoplasia 0.5461618827504622 1.2673272129257571 0.2050383139883826 1.0 1.0 7 O00330,P40763 2 +Increased hepatic glycogen content 0.5993101961246226 1.263997681444279 0.2062308591424524 1.0 1.0 5 Q93100,P31751 2 +Colon cancer 0.480546222369324 1.2614812798329191 0.207135500463016 1.0 1.0 17 O60566,Q15645,P54277,O43684,P42771,P20585,P52701,P39019,O96017,O43683 10 +Broad neck 0.4794200481270755 1.2537099946489922 0.2099474338121507 1.0 1.0 13 P21359,O60826,P62854,Q07864 4 +Duplication of thumb phalanx 0.4707922523600595 1.2536691078534292 0.2099623008578572 1.0 1.0 24 P62081,P60866,Q6W2J9,P62847,P08708,P62854,P42766,P39019,P62899 9 +Abnormal natural killer cell morphology 0.5970657993645345 1.2536614491106202 0.2099650857751576 1.0 1.0 5 P33991,O95394,O00203 3 +Reduced natural killer cell count 0.5970657993645345 1.2536614491106202 0.2099650857751576 1.0 1.0 5 P33991,O95394,O00203 3 +Centrally nucleated skeletal muscle fibers 0.5432624847617349 1.2528893492475384 0.2102459785314887 1.0 1.0 7 Q8NCE2,P50570,Q9Y5L0 3 +Triphalangeal thumb 0.4692421813049681 1.243763138464012 0.2135867506671278 1.0 1.0 24 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Abnormal mean corpuscular volume 0.4625211027341671 1.2437399538622655 0.2135952862020955 1.0 1.0 27 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Joint contracture of the hand 0.3412964753964717 1.2392413935804107 0.2152561153519574 1.0 1.0 51 Q9H4L7,Q15392,O14802,Q92917,P38935,Q9NPF4,Q6W2J9,P27635,O43318,P18074,A1X283,P28482,P57081,Q15042 14 +Posterior pharyngeal cleft 0.7587339504329513 1.2388406110690904 0.2154045309246641 1.0 1.0 3 Q00653,P29372 2 +Abnormality of the intrinsic pathway 0.474480986189449 1.228122082360199 0.2194011426207902 1.0 1.0 12 Q9Y487,P34949,Q9BV10 3 +Spontaneous abortion 0.7555493016198396 1.2265303142502249 0.2199991748207079 1.0 1.0 3 Q8NCE2 1 +Arnold chiari type i malformation 0.5905845836423647 1.2238209372716669 0.2210197841747874 1.0 1.0 5 Q00653 1 +Aplasia hypoplasia of the spleen 0.5901453070715769 1.221798988197112 0.2217836512913384 1.0 1.0 5 Q8TD19,P57076 2 +Chronic noninfectious lymphadenopathy 0.6225782044483846 1.2210137109003698 0.2220808285598119 1.0 1.0 4 Q9UER7 1 +Neoplasm of the genitourinary tract 0.3115514433615859 1.2191015041964604 0.2228056690632729 1.0 1.0 73 P60866,P54277,P42771,O60333,P62081,O75874,P62847,P08708,P48735,P62854,P28340,P21359,Q15645,O14965,P20585,P52701,P62899,Q01844,Q07864,Q9Y620 20 +Prenatal maternal abnormality 0.4731797193134445 1.2175852972465986 0.2233816044278125 1.0 1.0 13 O43772 1 +Metaphyseal dysplasia 0.4713394138058452 1.2143668949408144 0.2246076511900039 1.0 1.0 11 Q7Z2Z2,Q07864,Q99575,Q9NUQ7 4 +Pectus excavatum of inferior sternum 0.7523442019965874 1.2141466529625342 0.2246917275753461 1.0 1.0 3 P21359 1 +Retinal dysplasia 0.5351025750212453 1.2122691231816782 0.2254093792168237 1.0 1.0 7 P07437,P52732,O43505 3 +Focal impaired awareness seizure 0.4656053177823708 1.209286605839745 0.2265527548754249 1.0 1.0 23 Q05639,Q01105,Q96N67,P43034,Q9UHD2,O00429,Q08209,P67870,Q14353 9 +Trichorrhexis nodosa 0.7507036248226429 1.2078102940588642 0.2271202409595887 1.0 1.0 3 Q15477 1 +Exercise induced myoglobinuria 0.5870141896233786 1.2073893048782418 0.2272822524315043 1.0 1.0 5 P00558,P08237 2 +Vasculitis 0.4690195319376802 1.2066558349085046 0.2275647143023933 1.0 1.0 10 Q00653,Q96BN8,Q9Y3Z3,P49327,O95394 5 +Conjugated hyperbilirubinemia 0.6191698513507403 1.2059112644639192 0.2278517068142673 1.0 1.0 4 Q9Y5L0,P11166 2 +Abnormality of dna repair 0.6185958745131974 1.203368614389737 0.2288337077187969 1.0 1.0 4 P18074 1 +Bilateral microphthalmos 0.5533207525493106 1.1978439448340572 0.2309777756480793 1.0 1.0 6 P18074,Q08AM6 2 +Lumbar scoliosis 0.6159247423983307 1.1915385299102876 0.2334422401783671 1.0 1.0 4 O95352 1 +Thyroiditis 0.50911483193261 1.1888272722435809 0.2345076438021396 1.0 1.0 8 P00813,P49327 2 +Neoplasm of the tracheobronchial system 0.7444013138250194 1.1834858705651403 0.2366166430193512 1.0 1.0 3 P30154,Q14790 2 +Abnormal peripheral action potential amplitude 0.4860567400282235 1.1804252421416386 0.2378311273843372 1.0 1.0 9 Q92734,Q00796 2 +Short ribs 0.4667447710570409 1.1803797216607534 0.2378492234761275 1.0 1.0 13 Q08AM6,Q9BV10,O15357,Q14999 4 +Dolichocephaly 0.4225585531281136 1.1795268259026257 0.2381884612057514 1.0 1.0 36 Q4J6C6,Q03164,O15357,P27635,Q14738,Q08AM6,P42356,Q14999 8 +Intestinal polyp 0.4646173724095799 1.1785066860967082 0.2385946684041546 1.0 1.0 20 P28340,O60566,Q15645,P54277,O43684,Q07864,P42771,P20585,P52701,O96017,Q9UPY3,O43683 12 +Chorioretinal coloboma 0.5276341056633926 1.1751208846976395 0.239946356316467 1.0 1.0 7 Q6W2J9 1 +Abnormal anterior horn cell morphology 0.5267562018201097 1.170756846793387 0.2416965280345941 1.0 1.0 7 Q92734,P38935,Q99986,Q16637,P22314 5 +Abnormal soft palate morphology 0.3074628078802678 1.1702911950207022 0.241883804040258 1.0 1.0 73 P60866,Q9C0B1,Q15813,Q9BUF5,Q6PGP7,Q92796,O43505,Q9Y617,P62081,Q15392,O14802,P62847,Q15436,P08708,P62854,O43318,Q9Y4X0,P42766,P39019,Q13618,P36871,P62899,Q6W2J9,Q15058,Q93008,P62266,P46783,P78318 28 +Hyperorality 0.577225775737651 1.1623796802208377 0.245081273421043 1.0 1.0 5 Q05086,Q13501 2 +Generalized edema 0.5769504201257095 1.1611145397287828 0.2455953226066989 1.0 1.0 5 Q8IWV7 1 +Abnormal libido 0.5768568395556917 1.1606845918477855 0.2457701901415288 1.0 1.0 5 P42858 1 +Dialeptic seizure 0.2884975114021878 1.1556488497755424 0.2478248181823072 1.0 1.0 59 Q00653,Q05639,Q01105,Q96N67,P43034,Q9UHD2,O00429,P00374,Q08209,Q05086,P49419,Q93008,P67870,Q92796,Q14353 15 +Bronchiectasis 0.4598920094238348 1.14962900284919 0.2502967074098818 1.0 1.0 20 Q00653,P57076,Q86TI2,Q13432,P50851 5 +Recurrent bronchopulmonary infections 0.6042076556315539 1.1397100376061624 0.2544071239431393 1.0 1.0 4 P18074 1 +Abnormal eosinophil morphology 0.4569016020435306 1.1380330688752276 0.2551066741665788 1.0 1.0 10 P00813,P40763,P49327 3 +Abnormal large intestine morphology 0.3153345224396431 1.1327124181212591 0.2573350410391475 1.0 1.0 82 P60866,P54277,Q15056,P42771,Q6PGP7,O96017,P62081,O60566,P62847,O43684,P08708,P62854,O43318,P42766,P39019,Q8IWV7,O43683,P28340,Q15645,Q13043,O14965,Q08J23,P20585,P50851,P49327,P52701,Q9UPY3,P62899,Q6W2J9,Q07864,O15160,Q9Y620,P46783,Q15477 34 +Neoplasm of the adrenal cortex 0.5393186375732386 1.1309401424025785 0.2580802860487774 1.0 1.0 6 P42771,O75874,P48735 3 +Chronic mucocutaneous candidiasis 0.5392997284181709 1.1308499056892287 0.2581182707407454 1.0 1.0 6 O95394,P40763 2 +Thick cerebral cortex 0.6019591867996601 1.129779015105397 0.2585693527553505 1.0 1.0 4 Q9Y487,P43034 2 +Abnormal number of erythroid precursors 0.4470581623722227 1.1270833707882266 0.2597072334654291 1.0 1.0 26 P62081,P60866,P00491,P62847,P08708,P62854,P42766,P39019,P62899 9 +Generalized hyperpigmentation 0.4569310200416907 1.1237670384136793 0.2611118681946318 1.0 1.0 13 P40818,P36507,O00170,Q96IJ6 4 +Combined immunodeficiency 0.4535774460798937 1.1192496530208444 0.2630336480321469 1.0 1.0 10 Q00653,P11586,P00813,O60566,O95394 5 +Clubbing of fingers 0.5671155492263837 1.115974972576294 0.2644328477008151 1.0 1.0 5 Q86TI2 1 +Hereditary nonpolyposis colorectal carcinoma 0.4735752688903203 1.1129851692382056 0.2657147990842143 1.0 1.0 9 O14965,Q9Y620,O60566,P52701 4 +Oligodontia 0.4552143444700588 1.1112844406381843 0.2664459345733256 1.0 1.0 14 O14802,Q6W2J9,Q7Z6Z7,O43318,Q8IWV7 5 +Abnormality of the periungual region 0.5660876708233951 1.1112633252472572 0.2664550206756435 1.0 1.0 5 P40763 1 +Abnormal t cell proliferation 0.7251753125221849 1.1094897567530704 0.2672189608962783 1.0 1.0 3 P17812 1 +Reduced antigen specific t cell proliferation 0.7251753125221849 1.1094897567530704 0.2672189608962783 1.0 1.0 3 P17812 1 +Allergy 0.5140201887649323 1.1075350621528102 0.2680626617966495 1.0 1.0 7 O95394,P00813 2 +Basal cell carcinoma 0.4524673240235344 1.1069026442252257 0.2683360225353532 1.0 1.0 11 P60866,P54277,P43246,P18074,P52701,P49327,Q9UPY3 7 +Abnormal serum iron concentration 0.5651160357206998 1.1068106811645948 0.2683757892319507 1.0 1.0 5 Q15477,Q6PGP7 2 +Lymphoma 0.4366400947327399 1.10631333395593 0.2685909224171858 1.0 1.0 29 Q00653,P00491,P00813,Q9BUR4,Q08J23,Q07864,P42771,Q9Y620,P50851,P49327,P52701,O96017,O95394,P40763 14 +Female reproductive system neoplasm 0.451329056179099 1.1033762994403349 0.2698637846564349 1.0 1.0 21 P28340,P60866,O60566,Q15645,O14965,O43684,Q07864,P20585,Q9Y620,P52701,O96017,O43683 12 +Bilateral tonic clonic seizure 0.3187501505918915 1.102573688194202 0.2702123418061761 1.0 1.0 87 Q05639,P11310,Q7Z392,Q92796,Q14353,P27544,Q9BPU6,O60566,Q9NQZ5,P27635,O00429,P67870,Q9BTW9,O60231,Q08209,P40763,Q01105,O43776,O00330,Q05086,P13807,Q93008,Q13501,P49419 24 +Squamous cell carcinoma of the skin 0.595473666366435 1.101166380915526 0.2708242506384692 1.0 1.0 4 Q9H4L7 1 +Dicarboxylic aciduria 0.4464779168167893 1.0989195485467576 0.2718031590612704 1.0 1.0 24 P11310,O43772 2 +Supernumerary tooth 0.4916328926780537 1.098390954838703 0.2720338103662429 1.0 1.0 8 Q9Y4X0 1 +Neoplasm of the rectum 0.4532290127812789 1.0982682456859338 0.2720873735325297 1.0 1.0 15 P28340,P60866,P54277,Q07864,P42771,P20585 6 +Cerebral visual impairment 0.2926570066628561 1.0982487803187344 0.2720958709272427 1.0 1.0 66 Q05639,Q2M389,Q9UID3,Q96F86,Q96N67,P08243,P67870,Q08209,Q01105,P10589,Q08J23,Q9BSJ2,Q01433,P14854,Q96CU9,Q96C86,Q9NUQ7,Q9UBB6,Q15042 19 +Hypotelorism 0.4111700594798874 1.0948054117690245 0.2736018950288512 1.0 1.0 36 P21359,Q9BPU6,P48444,Q9NPF4,P26639,Q7Z6Z7,O43776,Q08J23,Q9BUK6,Q93008,P18074,P57081,Q15042,Q9NSD9 14 +Squamous cell carcinoma 0.4513148283186118 1.0887076721393418 0.276282817447198 1.0 1.0 14 Q9H4L7,Q9BUR4,P42771,P18074,P53602 5 +Irregular vertebral endplates 0.5293058252440531 1.0832164008037786 0.278712381652757 1.0 1.0 6 Q9NR45 1 +Flat acetabular roof 0.5594200245989951 1.0807331089637575 0.2798158508592006 1.0 1.0 5 Q9NR45 1 +Degeneration of the lateral corticospinal tracts 0.5077665267703684 1.0765702150073553 0.2816723166290487 1.0 1.0 7 Q9UHD2,Q13501 2 +Large intestinal polyposis 0.4661522298618931 1.0730039648870602 0.283269337187789 1.0 1.0 9 P28340,Q07864,P42771,P20585,O96017 5 +Colorectal polyposis 0.4661522298618931 1.0730039648870602 0.283269337187789 1.0 1.0 9 P28340,Q07864,P42771,P20585,O96017 5 +Abnormality of vitamin a metabolism 0.5270299383484839 1.0723876864784074 0.2835459363266843 1.0 1.0 6 Q7Z2Z2,Q9NSD9 2 +Abnormal pancreas size 0.4658943792785144 1.0716172777162667 0.2838919696996789 1.0 1.0 9 O00330,A5YKK6,P40763 3 +Lymphoproliferative disorder 0.7133472678411327 1.064171061231833 0.287251214013434 1.0 1.0 3 P50851,P17812 2 +Unconjugated hyperbilirubinemia 0.7126640911088656 1.0615592821502349 0.288435806861242 1.0 1.0 3 P11413 1 +Low levels of vitamin d 0.4432152933560788 1.0608532710795953 0.2887565883552674 1.0 1.0 10 Q01968,P46783,Q7Z2Z2,Q9NSD9 4 +Melanocytic nevus 0.4441557306801397 1.0545519508019348 0.291630288983018 1.0 1.0 12 P22681,P18074,Q06124 3 +Atrophy degeneration affecting the brainstem 0.4430561940651062 1.053585695182505 0.2920726412396894 1.0 1.0 11 P26358,Q9BTW9 2 +Long fingers 0.3107121268913579 1.0511057785027351 0.2932100104243171 1.0 1.0 84 Q03164,Q9P2J5,O00170,Q7Z6Z7,Q15555,Q9H4L7,Q9BPU6,O14802,P26196,P27635,Q9Y4X0,O43318,Q8IWS0,Q9Y263,O15357,P10589,O43776,P07437,Q08AM6,P28482,P53618,Q9BV10,Q93008,Q9Y285 24 +Bone spicule pigmentation of the retina 0.4613064231968866 1.0469707040078182 0.2951130900833449 1.0 1.0 9 Q3SYG4,Q15555 2 +Malignant neoplasm of the central nervous system 0.4361571795048743 1.0444495454377565 0.2962774510214689 1.0 1.0 25 P21359,P60866,O75874,P54277,Q15555,P48735,P42771,P07437,P20585,P52701,Q06124,O60333 12 +Abnormal speech prosody 0.5009645085533966 1.0429673168556066 0.2969634300412433 1.0 1.0 7 Q9Y3I1,Q6Y7W6,Q69YN2,O75165,Q04637 5 +Monotonic speech 0.5009645085533966 1.0429673168556066 0.2969634300412433 1.0 1.0 7 Q9Y3I1,Q6Y7W6,Q69YN2,O75165,Q04637 5 +Synovitis 0.7072282088830104 1.0408028847456845 0.2979670409494961 1.0 1.0 3 Q06124 1 +Generalized onset motor seizure 0.2999521543411078 1.0403530869933382 0.2981758886787404 1.0 1.0 54 Q05639,Q01105,Q96N67,O60566,P43034,O43776,P27635,Q14746,O00429,O00330,Q08209,Q05086,P49419,P67870,Q9BTW9,P40763,Q14353 17 +Cerebral hypomyelination 0.4430211205638448 1.04010810441017 0.2982896788239346 1.0 1.0 18 P49770,Q13144,P04350,P30566,Q9BTW9,P54136,Q9NW08 7 +Polysplenia 0.7067781427291525 1.0390864089430514 0.2987645512407622 1.0 1.0 3 P54577,P57076 2 +Abnormal hemoglobin 0.4333828038892814 1.0387632517631378 0.2989148560172756 1.0 1.0 26 P62081,P60866,P62847,P08708,P62854,O00330,P42766,P39019,P62899 9 +Recurrent lower respiratory tract infections 0.4331318221572405 1.0371504519772523 0.2996657454300946 1.0 1.0 26 Q00653,P11586,P00491,P00813,Q9BV10,Q13432,Q93008,P50851,Q9BTW9,O95394,P40763 11 +Decreased urine output 0.9370149253731358 1.0341657306060577 0.3010586918535267 1.0 1.0 2 O43772 1 +Oliguria 0.9370149253731358 1.0341657306060577 0.3010586918535267 1.0 1.0 2 O43772 1 +Abnormal circulating sulfur amino acid concentration 0.4790017716333633 1.0333627324275192 0.3014341799805689 1.0 1.0 8 P41440,P23526,Q99707,Q6PGP7,P16930 5 +Ulnar deviation of the hand 0.5184232688803854 1.031514268362583 0.3022997206527913 1.0 1.0 6 Q9BPU6 1 +Numerous pigmented freckles 0.7045372122029244 1.0305447762250504 0.3027543443677631 1.0 1.0 3 P18074 1 +Concave nail 0.7045372122029244 1.0305447762250504 0.3027543443677631 1.0 1.0 3 P18074 1 +Defective dna repair after ultraviolet radiation damage 0.7045372122029244 1.0305447762250504 0.3027543443677631 1.0 1.0 3 P18074 1 +Abnormal mean corpuscular hemoglobin concentration 0.7045372122029244 1.0305447762250504 0.3027543443677631 1.0 1.0 3 P18074 1 +Tiger tail banding 0.7045372122029244 1.0305447762250504 0.3027543443677631 1.0 1.0 3 P18074 1 +Low set nipples 0.7045372122029244 1.0305447762250504 0.3027543443677631 1.0 1.0 3 P18074 1 +Increased mean corpuscular hemoglobin concentration 0.7045372122029244 1.0305447762250504 0.3027543443677631 1.0 1.0 3 P18074 1 +Abnormal blood sodium concentration 0.4402063128742272 1.0278235643469504 0.3040328295963104 1.0 1.0 13 Q00653,Q9BV10,Q9UHD2,O95163,P08397,Q9UNF1 6 +Reduced protein s activity 0.7038022114903151 1.0277450221249818 0.3040697836264054 1.0 1.0 3 P34949 1 +Reduced protein c activity 0.7038022114903151 1.0277450221249818 0.3040697836264054 1.0 1.0 3 P34949 1 +Abnormality of the protein c anticoagulant pathway 0.7038022114903151 1.0277450221249818 0.3040697836264054 1.0 1.0 3 P34949 1 +Neuronal loss in basal ganglia 0.5466419542627473 1.022418868508299 0.3065826938668792 1.0 1.0 5 P42858 1 +Heat intolerance 0.5164283024037971 1.0220596664433204 0.3067526613550746 1.0 1.0 6 Q05086 1 +Abnormal renal resorption 0.702295011797914 1.0220066783964603 0.3067777395590598 1.0 1.0 3 Q01968 1 +Renal fanconi syndrome 0.702295011797914 1.0220066783964603 0.3067777395590598 1.0 1.0 3 Q01968 1 +Subcortical band heterotopia 0.7021983506009527 1.0216387941311045 0.3069518894181742 1.0 1.0 3 Q9BSJ2 1 +Subcortical heterotopia 0.7021983506009527 1.0216387941311045 0.3069518894181742 1.0 1.0 3 Q9BSJ2 1 +Gastrointestinal obstruction 0.44000379714904 1.0214181342550503 0.3070563772830939 1.0 1.0 15 P42771,Q15813,P08397,Q01844 4 +Abnormal platelet volume 0.4762619139425196 1.0193052328877987 0.308058080462751 1.0 1.0 8 Q6PGP7,P35579,P60953,Q15477 4 +Reduced factor xi activity 0.9322388059701504 1.0178717535812492 0.3087389067854664 1.0 1.0 2 P34949 1 +Nuclear cataract 0.5764556268396622 1.017619223104188 0.3088589483015838 1.0 1.0 4 P51570 1 +Diffuse cerebellar atrophy 0.4954460232909402 1.0157753185956029 0.30973639183132 1.0 1.0 7 P18074,Q06787 2 +Primary gonadal insufficiency 0.4549195905544682 1.0127545014075945 0.3111774380510868 1.0 1.0 9 P49770,Q14232,Q13144 3 +Generalized hypopigmentation 0.4545257118752751 1.0106483230170804 0.312184778756877 1.0 1.0 9 Q01968,Q6PGP7,O00203,Q15477 4 +Spinal muscular atrophy 0.4363878260257959 1.0104640766818846 0.3122730019925517 1.0 1.0 12 P38935,Q99986,Q14204,Q15813,Q8TD16,P22314 6 +Abnormality of the endometrium 0.4745007854741368 1.0102797880218068 0.3123612619268678 1.0 1.0 8 P28340,P20585,Q07864 3 +Recurrent pneumonia 0.4336196640767796 1.001411001314268 0.3166281475876267 1.0 1.0 22 Q00653,P11586,P00813,Q9BV10,Q13432,P50851,Q9BTW9,O95394,P40763 9 +Prominent nasolabial fold 0.5120554831448068 1.0013650355747092 0.3166503614381639 1.0 1.0 6 P21359,Q9Y487 2 +Abnormality of the nasolabial region 0.5120554831448068 1.0013650355747092 0.3166503614381639 1.0 1.0 6 P21359,Q9Y487 2 +Optic disc hypoplasia 0.5720671501165878 0.9984347595871104 0.3180685853990219 1.0 1.0 4 P10589,O14802 2 +Pectus excavatum 0.307088004711666 0.9959563443516076 0.3192713569258729 1.0 1.0 85 Q03164,Q15555,Q9BUK6,Q06787,Q14999,P22681,Q9Y487,P36507,O43318,Q9BTW9,Q9NSD9,P21359,O15357,O43776,A1X283,Q06124,O95352,Q6W2J9,P42356 19 +Focal aware seizure 0.695431472081203 0.9959261480110048 0.319286029498002 1.0 1.0 3 Q9UHD2,P49419 2 +Abnormality of the lymph nodes 0.3489489601688597 0.9953099151879748 0.3195855568881782 1.0 1.0 46 Q00653,P00813,Q14790,Q15645,Q96BN8,Q6W2J9,Q01844,P42771,Q9UER7,P49327,Q969U7,P40763,P28070,P22681 14 +Large hands 0.434975717149566 0.9946329641247892 0.3199148089325527 1.0 1.0 14 P21359,P08243,O00170 3 +Esophagitis 0.4906447179754771 0.99217610174994 0.3211116282146617 1.0 1.0 7 Q7Z392,O95394 2 +Generalized hirsutism 0.4271832186354937 0.9875913765106504 0.3233528113215254 1.0 1.0 25 Q03164,O00170,Q15555,P07437,Q15042,Q3SYG4,P40818 7 +Periorbital fullness 0.4311698449749455 0.9864100263258728 0.3239319469760977 1.0 1.0 22 Q96N67,P07437,Q93008,O14646,Q9UET6,Q92796,P57081,O75179 8 +Proportionate tall stature 0.9220895522388066 0.983386747252544 0.3254171303489115 1.0 1.0 2 P21359 1 +Suicidal ideation 0.6916443609987004 0.9815736330922372 0.3263099424601194 1.0 1.0 3 P42858 1 +Epileptic spasm 0.2787227336340395 0.9775653106602658 0.32828936123349 1.0 1.0 63 Q05639,O60701,Q01105,Q96N67,Q96C86,Q2M389,Q9NUQ7,P43034,Q08J23,P49419,Q9UBB6,P67870,Q9BTW9,P42356,P28482,Q96F86,Q08209,O60231 18 +Gingivitis 0.6901179637757081 0.9757969455824756 0.3291650986929286 1.0 1.0 3 P40763 1 +Medial flaring of the eyebrow 0.6894877937993403 0.973413447978968 0.3303478578538024 1.0 1.0 3 Q3SYG4 1 +Transposition of the great arteries 0.4863629187161904 0.9711821373259716 0.3314575873481229 1.0 1.0 7 P57076 1 +Joint hypermobility 0.3230068458945869 0.9667403236239882 0.3336738636553851 1.0 1.0 101 O75182,Q03164,Q7Z6Z7,O95394,Q9Y6D5,Q14999,P22681,Q9BPU6,O14802,P26196,Q9Y487,Q9Y4X0,Q8IWS0,P40763,Q01105,P21359,Q7LBC6,Q9Y263,Q8N0X7,Q08J23,P63241,Q05086,Q06124,P28482,Q13535,P42858,Q93008,O75179,Q15042 29 +Slender long bone 0.4304120806697422 0.966102403829184 0.3339929418133507 1.0 1.0 15 Q9Y487,Q08AM6,Q14999 3 +Abnormal phalangeal joint morphology of the hand 0.3618877302118925 0.9644066632091324 0.3348420828982981 1.0 1.0 43 Q9H4L7,O14802,Q92917,P38935,Q6W2J9,O43318,P18074,A1X283,P28482,P57081,Q15042 11 +Rheumatoid factor positive 0.6870707673932361 0.9642792360110614 0.3349059481352747 1.0 1.0 3 O95394,P49327 2 +Abnormality of the distal phalanx of the thumb 0.5335030752422487 0.9628037292199032 0.3356460289160781 1.0 1.0 5 O43318 1 +Thrombocytosis 0.4139762392357008 0.955564818679189 0.3392921429577253 1.0 1.0 29 P11586,P62081,P60866,P62847,P08708,P62854,P42766,P39019,Q15477,P62899 10 +Primary amenorrhea 0.4111087396471682 0.9532618141820288 0.3404574339236035 1.0 1.0 30 P49770,Q16740,Q9BUK6 3 +Diaphragmatic eventration 0.5610541659992374 0.950485950808136 0.3418653892061043 1.0 1.0 4 P08243,P38935 2 +Upper limb spasticity 0.4819960524740057 0.94982657393642 0.342200380800252 1.0 1.0 7 Q9BTW9 1 +Abnormality of urinary uric acid concentration 0.6825918184532669 0.947386343768062 0.3434419472915631 1.0 1.0 3 P00492,P00491 2 +Arthropathy 0.5300607696307525 0.9472557882666048 0.3435084537113462 1.0 1.0 5 P40763,O95163 2 +Fatigue 0.3038984807095733 0.9464892127109432 0.3438991217308973 1.0 1.0 86 P11310,P60866,O00170,Q70HW3,P54277,P42771,P18074,P22681,Q00653,O00429,P40763,P40818,P21359,Q4J6C6,Q9Y5L0,P49327,P52701,Q6W2J9,Q9UHD2,Q13501 20 +Bloodstream infectious agent 0.6822670540872409 0.9461632070173448 0.344065349150005 1.0 1.0 3 P17812 1 +Slurred speech 0.4225180481798086 0.9452135872252893 0.3445498441235497 1.0 1.0 10 O15020,Q9Y487,Q8N0X7 3 +Infection related seizure 0.4259342440211609 0.9443839570323904 0.34497347662399 1.0 1.0 20 P11310 1 +Protruding tongue 0.424463560782415 0.94324686449005 0.3455546474642315 1.0 1.0 12 Q9C0B1,Q05086,O60826,P67870,P42356 5 +Hypomimic face 0.422106660758463 0.9429326094578356 0.345715373999425 1.0 1.0 10 Q9Y3I1,Q6Y7W6,Q9Y263,O75165,Q04637 5 +Aplasia hypoplasia of the pubic bone 0.49811923606478 0.9357232302712728 0.3494157068125956 1.0 1.0 6 Q14999 1 +Infertility 0.4246915743428944 0.933321829767778 0.3506538273667114 1.0 1.0 15 P40818,P57076,Q06124 3 +Cortical dysplasia 0.4074922684928038 0.929232538527375 0.3527685879827893 1.0 1.0 30 O75182,P15311,Q96C86,Q2M389,Q9NUQ7,Q08J23,P07437,P08243,Q9UBB6,Q13885,Q96F86,O43505 12 +Alacrima 0.4962794234792231 0.927098332705417 0.3538754817452634 1.0 1.0 6 Q7Z392,O95163,Q96IJ6 3 +Arthrogryposis multiplex congenita 0.3916182284106914 0.9250593845070872 0.3549350183872506 1.0 1.0 35 Q15392,Q00535,Q06210,Q15058,O00330,P18074,Q8TD16,P40763,Q96AY3,P42356,Q9BTW9,Q08209 12 +Facial asymmetry 0.3913538003691103 0.923180921121982 0.3559129296873575 1.0 1.0 35 Q01105,Q03164,Q13535 3 +Abnormal circulating methionine concentration 0.4952215733414432 0.9221440300373572 0.3564534530132008 1.0 1.0 6 Q99707,P23526,P16930,Q6PGP7 4 +Abnormality of the 2nd toe 0.4194944674143498 0.9214375584213484 0.3568220273929441 1.0 1.0 11 Q6W2J9,Q93008,Q92796 3 +Hematological neoplasm 0.3050959953881559 0.9206695086533718 0.3572230001032568 1.0 1.0 89 P60866,P00813,Q9BUR4,Q9Y3Z3,P42771,O76094,P22314,O96017,O95394,P22681,Q00653,P62081,O60566,P62847,P08708,P62854,P42766,P39019,P40763,P21359,Q15645,Q08J23,P50851,P49327,Q06124,P52701,P62899,P00491,Q07864,P17812,Q9Y620,P46783 32 +Scapular winging 0.4178703184836854 0.919889070216576 0.3576307310523616 1.0 1.0 24 Q14331,Q9Y487,O00429,Q06210,Q9Y5L0,Q13501,Q06124,Q14999 8 +Abnormal labia minora morphology 0.456493673537488 0.9185575199351764 0.3583270599273818 1.0 1.0 8 Q15042 1 +Hypoplasia of the frontal lobes 0.4189271217151677 0.9182861881893968 0.3584690563014079 1.0 1.0 11 Q00534,P42695,Q08AM6 3 +Proximal muscle weakness 0.2736005559908262 0.9176247445654364 0.3588153586664115 1.0 1.0 63 P11310,P50570,P38935,Q92734,Q8NCE2,Q7Z392,Q9UHD2,Q14204,Q06210,P51114,Q9BUK6,Q13126,P08397,Q8TD16,Q13501,Q00796,P22314,Q13614 18 +Facial hypertrichosis 0.2709780273696758 0.916045971321425 0.359642783684543 1.0 1.0 61 Q03164,Q96N67,O00170,Q9NR45,Q9BSJ2,Q9Y4X0,Q69YN2,Q9BTW9,Q15042 9 +Increased circulating igg level 0.6742311137652881 0.9159778366062205 0.3596785196134462 1.0 1.0 3 O95394,P49327 2 +Agyria 0.6739444623340918 0.9149040309096618 0.3602420137516762 1.0 1.0 3 Q00535 1 +Hypokalemia 0.4358733745800387 0.9115534057221694 0.3620038598437556 1.0 1.0 9 Q99996,O00170,Q9H3U1,Q9UNF1,P40818 5 +Wide nose 0.3732761307485902 0.9051067106879886 0.3654088573212917 1.0 1.0 39 Q03164,Q9HCK8,Q9BV10,O60566,O00170,Q15645,Q9NR45,P43034,Q2TAL8,Q15436,O43684,Q6PGP7,Q15477,O95630,P40763,P52732 16 +Decreased lymphocyte apoptosis 0.8982089552238819 0.903101077864897 0.3664722520067398 1.0 1.0 2 Q14790 1 +Aplasia of the semicircular canal 0.8979104477611954 0.9021059837574444 0.3670005705407078 1.0 1.0 2 P22681 1 +Anisocytosis 0.4531930904640741 0.901875986940534 0.3671227486933852 1.0 1.0 8 P11413,P11172,Q8NBF2,Q96Q11 4 +Abnormality of blood volume homeostasis 0.6700507614213084 0.9003392320323595 0.3679397489725597 1.0 1.0 3 O00330,P40763 2 +Short upper lip 0.4893216734655029 0.8945807813881859 0.3710112291867147 1.0 1.0 6 Q08AM6 1 +Increased circulating antibody level 0.4181310597177727 0.8937896079917569 0.3714344703812275 1.0 1.0 18 P00813,Q96BN8,Q9Y5L0,P40763,P28070 5 +Abnormal muscle fiber type distribution 0.4141238664693314 0.8916766020140707 0.3725662983292337 1.0 1.0 11 Q8NCE2,Q14204,P50570,Q06210 4 +Non motor seizure 0.3127542403252171 0.8877379642165978 0.3746817194722531 1.0 1.0 50 Q00653,Q05639,Q01105,Q96N67,P43034,P00374,Q05086,Q93008,P49419,P67870,Q92796,P42356,Q08209 13 +Aplasia hypoplasia involving bones of the thorax 0.3784922849302954 0.8837207905267798 0.3768469543207464 1.0 1.0 37 Q03164,Q9BV10,Q6W2J9,Q08AM6,O60826,Q14999,Q13535 7 +Rhizomelia 0.4152474611952369 0.882619098056651 0.377442106387059 1.0 1.0 14 Q03164 1 +Abnormal growth hormone level 0.4046573615690593 0.8804538499758553 0.3786134954386111 1.0 1.0 28 Q00653,Q4J6C6,Q03164,O00170,Q07864,Q15813,P57081 7 +Primitive neuroectodermal tumor 0.4155654485372092 0.8803280771523602 0.3786816066488732 1.0 1.0 19 P21359,P60866,P54277,Q15555,P42771,P07437,P52701,Q06124,O60333 9 +Dyskinesia 0.2740154675885587 0.8797335202944576 0.3790036859822385 1.0 1.0 66 Q05639,P60866,Q2M389,Q9P0J0,P54277,Q8NC96,Q96F86,Q96QK1,O75165,P67870,Q08209,Q01105,Q6Y7W6,Q9Y4P8,Q08J23,P49591,P43246,P52701,Q04637,O75569,O95352,Q96C86,Q9NUQ7,Q9UBB6,Q14204,P15311 26 +Abnormal bronchus morphology 0.4110811307025118 0.8781707105503445 0.3798510842650782 1.0 1.0 24 Q00653,P57076,Q86TI2,Q13432,P50851 5 +Abnormal reticulocyte morphology 0.390052356833193 0.8684971747622346 0.3851222182783409 1.0 1.0 33 P11413,P62081,P60866,P08237,P62847,P08708,P62854,P48506,P42766,P39019,P49327,P62899 12 +Lymphedema 0.4125695274796134 0.8644857210934278 0.3873211209540455 1.0 1.0 15 O15357,P36507,P26358,Q06124,P28482,P22681 6 +Abnormality of the metaphysis 0.2689107623174754 0.8634679036060419 0.3878802590959189 1.0 1.0 63 O75874,P00813,P48444,O15357,Q9NUQ7,Q9NR45,Q2TAL8,Q9BUR4,P48735,Q13126,Q07864,O43318,Q9Y4X0,Q08AM6,Q99575,A1X283,Q06124,Q14999 18 +Psychotic mentation 0.5113282119806265 0.8632874138097472 0.3879794625072565 1.0 1.0 5 P40818 1 +Lack of skin elasticity 0.4121621255720299 0.8621889145270563 0.3885835688843109 1.0 1.0 15 P28340,Q9H4L7,P40818 3 +Diarrhea 0.2808224762886999 0.8606114117470633 0.3894520986492615 1.0 1.0 73 P11310,P34949,P00813,Q14790,Q96BN8,Q9Y6B6,P42771,P18074,Q9UER7,P08397,Q15477,P22681 12 +Increased urine proteinogenic amino acid derivative level 0.53912783751492 0.8560569296012975 0.3919662906518772 1.0 1.0 4 O96007,Q9NZB8,P48637 3 +Typical absence seizure 0.4107981541510604 0.8545078491074682 0.3928236622618368 1.0 1.0 15 Q01105,P67870,P49419 3 +Abnormality of the ribs 0.275249574972031 0.8521868431116586 0.3941103978385007 1.0 1.0 69 Q03164,P00813,Q9BV10,Q8NCE2,Q15813,O43318,Q08AM6,O60826,Q08209,Q14999,Q13535 11 +Poikilocytosis 0.4098124204779321 0.8468152980934718 0.3970980799053012 1.0 1.0 16 Q9Y6B6,P41440,P11172,Q9Y4X0 4 +Abnormal circulating lipid concentration 0.2890436943491472 0.8463087296880317 0.3973805391835423 1.0 1.0 81 P28340,P11310,Q15392,O75880,Q9BV10,Q92734,O43772,Q9Y6B6,P31751,Q9Y5L0,P28070 11 +Increased connective tissue 0.4601988826966741 0.8442616829474708 0.398523192693093 1.0 1.0 7 Q9Y5L0,P31751 2 +Ridged nail 0.4600068085561859 0.8433404244535779 0.3990380805850693 1.0 1.0 7 P18074,Q13535 2 +Renovascular hypertension 0.4227358225080834 0.8427100687696855 0.3993906145940695 1.0 1.0 9 Q08AM6 1 +Vaginal neoplasm 0.5064547870317168 0.8416490455670491 0.399984427583679 1.0 1.0 5 O43684,O60566,Q15645 3 +Decreased lacrimation 0.4593783276496961 0.8403272409642387 0.4007249317816144 1.0 1.0 7 Q03001,Q7Z392,O95163,Q96IJ6 4 +Neoplasm of the stomach 0.4059471879140076 0.839921345458816 0.4009524886053768 1.0 1.0 23 P60866,O60566,Q15645,O14965,O43684,P11802,P42771,P20585,Q9Y620,P52701,O96017,O43683 12 +Abnormality of endocrine pancreas physiology 0.5058897335504068 0.8391464208042586 0.4013871493694794 1.0 1.0 5 O00330,P40763 2 +Celiac disease 0.5347185898534321 0.837269962612039 0.4024408392513325 1.0 1.0 4 Q9Y5L0 1 +Carcinoma 0.5050799967629136 0.8355624304106903 0.4034011116895424 1.0 1.0 5 P28340 1 +Decreased testicular size 0.4049281316634571 0.8338113825109205 0.4043872801380428 1.0 1.0 23 P27635,O43318,P18074,Q8IWS0,Q06787,Q14999 6 +Speech articulation difficulties 0.4757775452496507 0.8317999623627818 0.4055218651611003 1.0 1.0 6 P21359 1 +Partial agenesis of the corpus callosum 0.4065713032736612 0.8307918329638303 0.4060912371684106 1.0 1.0 15 P18074,P26639,Q15392,P57081 4 +Severe b lymphocytopenia 0.876119402985077 0.8301137631952425 0.4064744662377477 1.0 1.0 2 P00813 1 +Absent earlobe 0.8749253731343309 0.8262086042254031 0.4086857682025364 1.0 1.0 2 Q13535 1 +Long penis 0.8749253731343295 0.8262086042253984 0.4086857682025391 1.0 1.0 2 O00170 1 +Parietal bossing 0.8749253731343283 0.8262086042253944 0.4086857682025413 1.0 1.0 2 Q06124 1 +Genital neoplasm 0.3539634760493599 0.8246178133237209 0.4095886049293507 1.0 1.0 41 P28340,P60866,O75874,Q15645,P54277,O14965,Q01844,P48735,Q07864,P42771,P20585,Q9Y620,P52701 13 +Macroscopic hematuria 0.8734328358208974 0.8213333522023207 0.4114564150640305 1.0 1.0 2 P07741 1 +Uric acid nephrolithiasis 0.8734328358208974 0.8213333522023207 0.4114564150640305 1.0 1.0 2 P07741 1 +Respiratory failure requiring assisted ventilation 0.4551146580672883 0.8199372418361133 0.4122518848091832 1.0 1.0 7 Q92734,P38935,Q9BTW9 3 +Abnormal bronchus physiology 0.4730071808424029 0.8190547436914316 0.4127551808171739 1.0 1.0 6 P18074,Q9UER7 2 +Bronchospasm 0.4730071808424029 0.8190547436914316 0.4127551808171739 1.0 1.0 6 P18074,Q9UER7 2 +Cavernous hemangioma 0.4728913604309513 0.8185226813832557 0.4130587962171195 1.0 1.0 6 Q8NCE2,P36507 2 +Poor appetite 0.4027476463108461 0.8173404037573108 0.4137339231165944 1.0 1.0 13 Q70HW3,Q9UER7 2 +Palpebral edema 0.4718733931132785 0.813849020439579 0.4157314485553982 1.0 1.0 6 O00170 1 +Disturbance of facial expression 0.4526042065430171 0.8079754717345364 0.4191047024311749 1.0 1.0 7 Q8NCE2,P49419 2 +Abnormality of the common coagulation pathway 0.402380541387315 0.8049899725105962 0.420825466303486 1.0 1.0 16 Q6W2J9,P34949,Q9BV10,P40763 4 +Iris hypopigmentation 0.4981391412772359 0.8049591359764596 0.4208432612905346 1.0 1.0 5 Q05086,O00203 2 +Abnormality of hair growth 0.469519350101386 0.8030603575579986 0.4219398492450552 1.0 1.0 6 P04080,P46778,P36507,Q02750 4 +Abnormal myeloid cell morphology 0.5262869662265989 0.801566770724867 0.4228036057130266 1.0 1.0 4 P41440 1 +Anasarca 0.8668656716417902 0.7999661491706155 0.4237304100310064 1.0 1.0 2 Q8IWV7 1 +Congenital malformation of the left heart 0.5254615018332042 0.798088090314817 0.4248193722446012 1.0 1.0 4 O60826 1 +Bronchitis 0.4321570837983778 0.7968018350595621 0.4255661291922172 1.0 1.0 8 P57076 1 +Productive cough 0.4318416280046525 0.7952449983200436 0.4264710009964951 1.0 1.0 8 Q6W2J9,P57076 2 +Exostoses 0.5246511913170289 0.7946762997000065 0.4268018221982448 1.0 1.0 4 P48735,Q06124 2 +Abnormal astrocyte morphology 0.4007019895232658 0.7941548442994187 0.4271052926787022 1.0 1.0 17 P21359,O75874,P48735,P42771,P20585,Q13501,P52701 7 +Abnormal blood monovalent inorganic cation concentration 0.3971435060070803 0.7937984112552925 0.427312797714934 1.0 1.0 24 Q00653,Q99996,P04075,O00170,Q9BV10,Q9UHD2,Q13618,O95163,P08397,Q9H3U1,Q9UNF1,P40818 12 +Abnormality of the pulmonary vasculature 0.3499226538914119 0.7937768513018278 0.4273253511813162 1.0 1.0 41 Q15392,Q9BPU6,P26196,Q6W2J9,Q7Z6Z7,P57076,P42858,Q15477,Q06124,P22681 10 +Axonal loss 0.3947638948900155 0.7934916486841971 0.4274914330499706 1.0 1.0 10 P41440,Q9NX46,P35251,Q9NZB8,O96007,Q92597,Q8N9N2,Q27J81 8 +Hypoplastic ischia 0.8647761194029884 0.7931969692991938 0.4276630730026667 1.0 1.0 2 Q14999 1 +Abnormality of the ischium 0.8647761194029884 0.7931969692991938 0.4276630730026667 1.0 1.0 2 Q14999 1 +Molar tooth sign on mri 0.5240863862039153 0.7922999945381275 0.4281857748823001 1.0 1.0 4 O43924,Q96KP1 2 +Dystrophic fingernails 0.3939568761939946 0.7891583063914367 0.4300194871621761 1.0 1.0 10 P18074,P36507,P40763 3 +Ulnar deviation of the hand or of fingers of the hand 0.3984298915775288 0.7890899128891488 0.4300594571169571 1.0 1.0 14 O43318,Q9BPU6,Q15042 3 +Leukemia 0.2610684716412582 0.7883781498791407 0.4304755476891326 1.0 1.0 62 P60866,Q9Y3Z3,P42771,Q7Z2Z2,O96017,P22681,P62081,O60566,P62847,O43684,P08708,P62854,P11766,P42766,P39019,O43683,P21359,Q15645,Q08J23,Q06124,P62899,O75792,P46783,P52732 24 +Tonic seizure 0.3947018416705898 0.7866548571771823 0.431483936984756 1.0 1.0 25 Q05639,Q01105,Q96N67,P43034,P27635,Q14746,P67870,Q9BTW9,Q08209 9 +Pseudobulbar signs 0.3933481684002682 0.7858932606253067 0.4319300231577156 1.0 1.0 10 P42356,P26358 2 +Laryngeal dystonia 0.8623880597014956 0.7854787099625131 0.4321729481214065 1.0 1.0 2 O75569 1 +Somatic mosaicism 0.6386500353898392 0.7845461753296621 0.4327196986664912 1.0 1.0 3 P00813 1 +Hyperpigmentation of the skin 0.2971007336106157 0.7837766346781666 0.4331711862462515 1.0 1.0 93 O00170,Q7Z392,Q7Z6Z7,Q9BUR4,Q15555,P18074,Q96IJ6,P22681,O60333,Q9H4L7,Q9BPU6,O60566,P36507,Q8IWV7,P40818,P21359,Q15645,Q9Y5L0,P07437,A1X283,P52701,Q06124,P28482,P42858,Q15477 25 +Upper limb asymmetry 0.861791044776119 0.7835521766585724 0.4333029265239001 1.0 1.0 2 Q15555 1 +Camptodactyly of toe 0.4473019664673018 0.7828253243661862 0.4337296941278872 1.0 1.0 7 Q6W2J9,Q14738 2 +Abnormal b cell subset distribution 0.860597014925376 0.7797027881688419 0.4355658373220721 1.0 1.0 2 P17812 1 +Abnormal rib cage morphology 0.2828065746010682 0.7781706365595558 0.4364684248912271 1.0 1.0 81 P22681,Q03164,P00813,Q9BV10,Q92917,O14802,O15357,Q8NCE2,Q6W2J9,Q15813,O43318,Q08AM6,O60826,Q06124,Q08209,Q14999,Q13535 17 +Wide intermamillary distance 0.394329889398739 0.7770042923367882 0.4371562379145948 1.0 1.0 24 P21359,P48444,Q15555,Q96KP1,P07437,Q9Y4X0,Q06124,P22681 8 +Small anterior fontanelle 0.6360913628671432 0.7752613301055359 0.4381852545509141 1.0 1.0 3 Q13535 1 +Bladder neoplasm 0.4274888067239653 0.7738281754536868 0.4390324082743371 1.0 1.0 8 O14965,O96017,Q9Y620,O60566 4 +Dysdiadochokinesis 0.3960378884363056 0.7680347261487264 0.4424665542764427 1.0 1.0 17 O15020,P41440,P04350,P49589,Q9BUK6,Q13501,Q06787 7 +Thick upper lip vermilion 0.4082510664196968 0.7680223474128076 0.4424739083536833 1.0 1.0 9 Q9UID3,P62081 2 +Neutrophilia 0.8540298507462717 0.7586207550389996 0.4480794533818866 1.0 1.0 2 Q96BN8 1 +Pancreatic adenocarcinoma 0.3882051600989359 0.7584295752087956 0.4481938581706779 1.0 1.0 10 P54277,P42771,P60866 3 +Agnosia 0.4417466488567381 0.7566523559286571 0.4492581656937906 1.0 1.0 7 P54277,P60866 2 +Abnormality of the pubic bone 0.4415404557017372 0.7556846055427127 0.4498383161245443 1.0 1.0 7 Q14999 1 +Breast carcinoma 0.3916003610150906 0.7548622667296673 0.4503316282780267 1.0 1.0 23 P28340,P21359,O75874,Q14790,P48735,Q07864,P42771,P52701,Q13535 9 +Prominent occiput 0.3901889103612493 0.7546557214382119 0.4504555806995336 1.0 1.0 12 Q9Y617,O60826,O15111 3 +Lipid accumulation in hepatocytes 0.2627722509879601 0.7534157524883979 0.4512001197414645 1.0 1.0 66 P11310,O75880,O43772,Q9Y6B6,P31751 5 +Exercise induced muscle cramps 0.4862080435074749 0.7528950514913029 0.4515129820196064 1.0 1.0 5 P00558,P06737,P08237 3 +Congenital malformation of the right heart 0.3885768233778705 0.7460102089536701 0.4556612480409487 1.0 1.0 12 P57076,A1X283 2 +Abnormal glial cell morphology 0.2607439307657198 0.7443616963157803 0.4566576853970732 1.0 1.0 65 P49770,P60866,Q9Y3I1,P54277,Q14232,P42771,O96017,O75874,P48735,Q9BTW9,P21359,Q7LBC6,Q6Y7W6,Q13144,O96007,P20585,P52701,Q92734,Q99986,Q9UHD2,P42858,Q13501 22 +Abnormal adipose tissue morphology 0.265172912181663 0.7442145881638833 0.4567466638529001 1.0 1.0 55 P28340,O14802,Q9BV10,Q96BN8,Q9Y487,P26639,Q9Y3Z3,P31751,Q9BUK6,P18074,P49327,Q969U7,P28070,P40818 14 +Macroorchidism 0.4841232902628912 0.7438751495654745 0.456952010668588 1.0 1.0 5 P21359 1 +Abnormality of the foot musculature 0.5124422498709515 0.7436566126396785 0.4570842442348775 1.0 1.0 4 Q8NCE2 1 +Abnormal lymphocyte morphology 0.3342154610580345 0.7425546718902476 0.4577513401582895 1.0 1.0 43 Q00653,P11586,P33991,P00813,P00491,Q9BV10,Q14790,Q9NRZ9,Q96BN8,O00203,P17812,Q13432,P50851,Q6PGP7,P49327,Q15477,O95394,P28070 18 +Multiple cafe au lait spots 0.3903899038733842 0.7413828241712521 0.4584613556855712 1.0 1.0 15 P21359,O60566,Q15645,P36507,O43684,P52701,O43683 7 +Severe viral infection 0.4382678322696718 0.7403618141465192 0.4590804826524506 1.0 1.0 7 P17812 1 +Broad femoral neck 0.6263523096840321 0.7401620482494312 0.4592016728206181 1.0 1.0 3 Q9NUQ7 1 +Broad foot 0.4022612177253142 0.7375852858307435 0.4607664995600771 1.0 1.0 9 P27635,O00170,Q8IWS0 3 +Aqueductal stenosis 0.419867563439268 0.7366420528255354 0.4613400544779189 1.0 1.0 8 P21359,P57081 2 +Impaired distal vibration sensation 0.4547936464393037 0.736236992245841 0.4615864834224537 1.0 1.0 6 Q5TAQ9 1 +Biventricular hypertrophy 0.6251717110884514 0.7359344080118506 0.4617706162276849 1.0 1.0 3 Q9BV10 1 +Simple ear 0.453913047027828 0.7322805671802389 0.4639973378653717 1.0 1.0 6 A1X283,O60231 2 +Chondrosarcoma 0.6238413612540266 0.7311778578433205 0.4646705229240873 1.0 1.0 3 P48735 1 +Dilation of lateral ventricles 0.3877631102620107 0.7280264970775754 0.4665973663509155 1.0 1.0 22 Q05639,Q01105,Q9UID3,Q14738,P67870,Q08209,Q15042 7 +Neoplasm of the pituitary gland 0.3874369536940292 0.7253349429441012 0.4682465738056487 1.0 1.0 15 P60866,O00170,P54277,P48735,P52701,P40818 6 +Chronic sinusitis 0.4793429196629252 0.7232867657325174 0.4695037218390951 1.0 1.0 5 P57076 1 +Neoplasm by histology 0.3032545324462391 0.7208618906452732 0.4709944920031279 1.0 1.0 104 P60866,P54277,Q15555,P42771,P18074,O60333,P62081,O75874,Q15392,O60566,P62847,P08708,P62854,Q13126,P48735,P28340,P21359,Q15645,O14965,P07437,P20585,P49327,Q06124,P52701,Q9H269,P62899,Q01844,Q07864,Q9Y620,Q13501,Q15477 31 +Visual hallucinations 0.4498208996253225 0.7139592803588433 0.4752523590949189 1.0 1.0 6 Q9Y3I1,Q6Y7W6,O75165,Q04637 4 +Lewy bodies 0.4498208996253225 0.7139592803588433 0.4752523590949189 1.0 1.0 6 Q9Y3I1,Q6Y7W6,O75165,Q04637 4 +Abnormal cortical bone morphology 0.3862376459958776 0.7139289381855595 0.4752711221382348 1.0 1.0 20 P21359,P42695,Q15813,Q00534,A1X283,Q9NSD9 6 +Thoracolumbar scoliosis 0.4148236907389415 0.7122693153566335 0.4762980213357008 1.0 1.0 8 Q93008,P27635,Q99575,O95352 4 +Recurrent staphylococcus aureus infections 0.8394029850746281 0.7122426793782254 0.4763145123759476 1.0 1.0 2 P40763 1 +Recurrent staphylococcal infections 0.8394029850746281 0.7122426793782254 0.4763145123759476 1.0 1.0 2 P40763 1 +Neonatal respiratory distress 0.3831544652804832 0.7112211842434256 0.4769471831014793 1.0 1.0 24 P57076,Q14999,P49419 3 +Large forehead 0.4316010000463728 0.7093729506029907 0.4780930689547693 1.0 1.0 7 Q9Y4X0 1 +Aplasia of the fingers 0.3749009327693621 0.7061820727765834 0.4800749174492218 1.0 1.0 29 P62081,P60866,P62847,P08708,P62854,P42766,Q08AM6,P46783,P39019,P62899 10 +Hemangiomatosis 0.8370149253731343 0.7047510036442463 0.4809652047096029 1.0 1.0 2 P48735 1 +Visceral angiomatosis 0.8370149253731343 0.7047510036442463 0.4809652047096029 1.0 1.0 2 P48735 1 +Lymphangioma 0.8370149253731343 0.7047510036442463 0.4809652047096029 1.0 1.0 2 P48735 1 +Joint contractures involving the joints of the feet 0.37709169552668 0.6999053861964386 0.4839863934673849 1.0 1.0 10 Q6W2J9,P63241,Q14738 3 +Focal onset seizure 0.2834053436814994 0.6996162350085111 0.4841670008904695 1.0 1.0 88 Q05639,Q2M389,P54136,Q96F86,Q14353,Q9Y6D5,Q9BPU6,Q96N67,O14802,P27635,O00429,P67870,Q08209,Q01105,P21359,O43776,Q08J23,P53618,P43034,Q96C86,Q9NUQ7,Q9UHD2,Q9UBB6,P49419,P42356 25 +Sprengel anomaly 0.369302493169165 0.6977442473728425 0.4853371513121201 1.0 1.0 31 P62081,P60866,P62847,P08708,P62854,O43318,P42766,P39019,Q06124,P62899 10 +Difficulty running 0.3794788681038061 0.6976983869316026 0.4853658371637872 1.0 1.0 12 Q9Y5L0,Q8TD16,Q06210 3 +Abnormality of circulating adrenocorticotropin level 0.393974960827479 0.6959801802110334 0.4864412420544324 1.0 1.0 9 Q9UER7,O00170,P40818 3 +Aplasia hypoplasia of the abdominal wall musculature 0.4724436033087391 0.6938181626196827 0.4877962508875511 1.0 1.0 5 P22681 1 +Addictive behavior 0.4102670971527575 0.6904278685193248 0.4899251562566673 1.0 1.0 8 Q6W2J9,P40763,P42858 3 +Limitation of movement at ankles 0.4714640082807113 0.6896588887097777 0.4904087249674145 1.0 1.0 5 Q05086 1 +Developmental cataract 0.2459169992218609 0.6881412835565227 0.4913638151297752 1.0 1.0 57 P62081,P60866,Q6W2J9,P36507,P62847,P08708,P62854,P18074,P48449,Q15042,P62899,O60333 12 +Neurogenic bladder 0.4092889498637878 0.6857622054328194 0.4928630730155185 1.0 1.0 8 O43318,Q9Y3I1,Q9BTW9 3 +Narrow forehead 0.2964766320891804 0.685542894271709 0.4930014027873064 1.0 1.0 49 P21359,Q96N67,Q9NPF4,P26196,P36507,Q9BSJ2,Q14738,P49589,Q93008,Q01433,Q2VPK5,Q9BTW9,P28482,Q15042 14 +Abnormal morphology of the musculature of the neck 0.3803820084657042 0.6842193088770291 0.4938366912156708 1.0 1.0 16 Q9H269,O75569,P04350 3 +Small for gestational age 0.2806324128162445 0.6827340496655647 0.4947749098448557 1.0 1.0 87 P60866,Q7Z6Z7,P18074,Q92796,Q14999,P62081,O60566,P38935,P62847,P08708,P62854,P42766,P39019,Q8IWV7,Q9NSD9,Q08J23,Q9UET6,P62899,P51570,Q9BV10,P50570,P49589,Q93008,P46783,Q15477,O95630 26 +Plagiocephaly 0.3531465335794543 0.6819329655586228 0.4952813393173885 1.0 1.0 36 O60701,Q01105,Q9BPU6,Q9BV10,Q9Y3Z3,Q14738,P63241,Q9BTW9,P28482,Q08209 10 +Urinary retention 0.4973309359037436 0.6816353644647195 0.4954695473298167 1.0 1.0 4 P08397 1 +Abnormal synaptic transmission at the neuromuscular junction 0.374048903610181 0.680171708046771 0.4963957441551536 1.0 1.0 27 P11310,Q13501,Q92734,Q06210 4 +Submucous cleft of soft and hard palate 0.3776820666346571 0.6796026465544011 0.4967560934600521 1.0 1.0 24 Q9Y617,Q15392,Q6W2J9,P36507,Q08J23,Q14738,P49589,Q9Y4X0,P62266,O43505 10 +Hypotension 0.3753562013436969 0.6794611326792883 0.496845726555625 1.0 1.0 26 Q00653,O00170,O43772,Q9Y5L0,Q9UER7,Q96IJ6,Q06787,P22681 8 +Hemolytic anemia 0.3586697050258436 0.6788087177167426 0.4972590693749268 1.0 1.0 34 P41440,P00813,O95394,Q00653,P11413,P04075,P08237,P48506,P40763,P06744,P11166,P29144,P50851,P49327,P00491,P00568,Q969U7,P00558,P06132 19 +Neuronal loss in central nervous system 0.3775222222848199 0.6763275185129325 0.4988327248239002 1.0 1.0 14 P26358,Q08AM6,Q9BTW9 3 +Widened subarachnoid space 0.3717410155817819 0.6760095717461185 0.4990345679239514 1.0 1.0 28 Q01105,Q05639,Q9BV10,O43776,Q93008,P49419,P67870,Q92796,Q14204,Q08209 10 +Flexion contracture of digit 0.2648899356114683 0.6744210007948499 0.5000436949112361 1.0 1.0 74 Q9H4L7,O14802,Q8N0X7,P38935,Q92917,Q9BV10,Q6W2J9,Q7Z6Z7,P27635,Q14738,O43318,P18074,P63241,O60826,A1X283,P28482,P57081,Q15042 18 +Mandibular prognathia 0.3448163713240345 0.6710181180175363 0.502208987567615 1.0 1.0 38 O00170,Q06210,Q9BUK6,Q05086,A1X283,P67870,Q06787,Q14999 8 +Caesarian section 0.4944930358514844 0.6701442698084829 0.5027658263438106 1.0 1.0 4 O14802 1 +Round face 0.3781072367130228 0.6687517068906323 0.5036538775912165 1.0 1.0 20 Q03164 1 +Difficulty standing 0.4660846264553682 0.6669345039888656 0.5048139701756789 1.0 1.0 5 Q92734 1 +Migraine 0.3762812214605145 0.6667104425284055 0.5049571072785168 1.0 1.0 23 P21359,P60866,O00170,P54277,Q9NQZ5,O00429,P49327 7 +Self mutilation 0.3704515505882301 0.6655404492900839 0.5057048809166407 1.0 1.0 10 Q6W2J9,O95352 2 +Right ventricular hypertrophy 0.6046474945665874 0.6634802741290124 0.5070230089150778 1.0 1.0 3 O95630 1 +Reduced pancreatic beta cells 0.8232835820895541 0.6621446907596718 0.5078784967457406 1.0 1.0 2 P40763 1 +Subependymal cysts 0.6042513922036352 0.6621027196511136 0.5079053929786679 1.0 1.0 3 Q9BSJ2 1 +Myositis 0.3694885321947145 0.6605974560276338 0.5088705009204406 1.0 1.0 10 Q969U7,P28070,P49327 3 +Polyhydramnios 0.2567838073865817 0.6580945532448854 0.5104773755914482 1.0 1.0 55 Q7LBC6,Q9BV10,O60566,O15357,Q15645,Q8NCE2,Q70HW3,P50570,P27635,Q9Y4X0,Q08AM6,Q9BTW9,P22681 13 +Hepatocellular carcinoma 0.3752318496187135 0.6571176336207957 0.5111052813682733 1.0 1.0 22 P60866,Q14790,P54277,Q9Y5L0,P08397,P49327,P52701 7 +Pulmonary artery stenosis 0.375243953082325 0.656791746225416 0.5113148320905756 1.0 1.0 16 P22681,Q6W2J9,Q15477,Q06124 4 +Distal upper limb muscle weakness 0.4026598242158938 0.6543679142482751 0.5128748008582027 1.0 1.0 8 Q00796 1 +Hypopituitarism 0.3489917371944938 0.6543338062228546 0.5128967703296758 1.0 1.0 36 Q00653,Q4J6C6,Q03164,O00170,Q07864,Q15813,Q96IJ6,P57081 8 +Pleural effusion 0.3708351410014977 0.652630505354944 0.5139945143349858 1.0 1.0 12 Q9UID3,P49327,P22681 3 +Thickened helices 0.4021730454981247 0.6520787072623612 0.5143503993114913 1.0 1.0 8 P22681,Q06124 2 +Aplasia hypoplasia of toe 0.3413195323630453 0.647138322706495 0.517542424662661 1.0 1.0 38 Q08AM6,Q03164,P00813,Q9BPU6 4 +Pruritus 0.3723642056032723 0.6446944374986646 0.5191252217471225 1.0 1.0 23 P00813,Q15126,Q9Y5L0,P40763,P22681 5 +Limb undergrowth 0.2681971898224868 0.6440159069529074 0.5195651190688415 1.0 1.0 53 Q03164,Q15392,Q9BV10,Q14999,Q13535 5 +Macrocephaly at birth 0.8173134328358236 0.6438836476654747 0.5196508863232749 1.0 1.0 2 Q8NCE2 1 +Dilation of virchow robin spaces 0.8167164179104482 0.642066737571127 0.5208298517836485 1.0 1.0 2 P27635 1 +Impaired distal proprioception 0.4873279593482698 0.6413735187821529 0.5212800337795291 1.0 1.0 4 O14802 1 +Alveolar cell carcinoma 0.8158208955223916 0.6393445593656238 0.5225988067752914 1.0 1.0 2 Q14790 1 +Cubitus valgus 0.3725792374805872 0.6381406900499049 0.5233821011787416 1.0 1.0 19 P21359,Q6W2J9,P36507,Q06124,P28482,P22681 6 +Absence of subcutaneous fat 0.4322379114818246 0.6365674624918215 0.5244066248109425 1.0 1.0 6 P18074,O14802 2 +Myelodysplasia 0.2851333976781036 0.6361533456766996 0.5246764783752125 1.0 1.0 50 P60866,P42771,O76094,Q7Z2Z2,P22314,O96017,P62081,O60566,P62847,O43684,P08708,P62854,P11766,P42766,P39019,P21359,Q15645,Q06124,P62899,P46783 20 +Delayed ability to walk 0.2598551098344388 0.6343362597773341 0.5258613976494704 1.0 1.0 73 Q7Z6Z7,Q16512,Q9BPU6,P27635,Q96D71,P67870,Q01105,Q7LBC6,O43776,Q9Y5L0,Q05086,Q01433,P48449,P57081,O95352,P53618,Q14738,Q9UBB6,Q15042 19 +Abnormal blood transition element cation concentration 0.3680429770516756 0.632109111378229 0.5273155818568518 1.0 1.0 13 Q9Y487,Q14746,Q10567,P41252,Q15477,Q6PGP7 6 +Gaze evoked nystagmus 0.3651157442152466 0.6303661606727384 0.5284550454044465 1.0 1.0 11 O15020,P41440 2 +Metrorrhagia 0.4141980884626165 0.6301003906119166 0.5286289041490098 1.0 1.0 7 Q6W2J9,P40818 2 +Abnormality of vitamin b12 metabolism 0.3650349650559152 0.629955787421921 0.5287235114187887 1.0 1.0 11 P41440,Q99707 2 +Large face 0.2569057289212728 0.627961996332567 0.5300288360897341 1.0 1.0 71 P21359,Q9BPU6,Q9BV10,O00170,Q16512,P26196,Q6W2J9,Q7Z6Z7,P36507,P27635,Q06210,Q14738,Q9BUK6,O96007,P42858,P28482,Q06787,O95352 18 +Abnormal anatomic location of the heart 0.3642300656892212 0.6258713351070798 0.5313993375136097 1.0 1.0 11 Q6W2J9,P57076 2 +Abnormal blood potassium concentration 0.3677046168956476 0.625087777744811 0.5319134492182238 1.0 1.0 14 Q99996,P04075,O00170,Q13618,Q9H3U1,Q9UNF1,P40818 7 +Overlapping fingers 0.3622999402134662 0.6240507912028537 0.532594229391913 1.0 1.0 10 P42356,Q2VPK5 2 +Exercise induced rhabdomyolysis 0.5928034143710377 0.6226632768143437 0.5335058198390126 1.0 1.0 3 P04075 1 +Prominent veins on trunk 0.592714243057618 0.6223590101514876 0.5337058269819241 1.0 1.0 3 Q9Y487,P36543 2 +Abnormal circulating apolipoprotein concentration 0.592714243057618 0.6223590101514876 0.5337058269819241 1.0 1.0 3 Q9Y487,P36543 2 +Abnormal cutaneous elastic fiber morphology 0.592714243057618 0.6223590101514876 0.5337058269819241 1.0 1.0 3 Q9Y487,P36543 2 +Abnormal subcutaneous fat tissue distribution 0.5927142430576179 0.622359010151487 0.5337058269819246 1.0 1.0 3 Q9Y487,P36543 2 +Apraxia 0.2501070209229431 0.6183065943652294 0.5363732558224075 1.0 1.0 66 Q9BPU6,Q8N0X7,Q7Z392,Q7Z460,Q7Z6Z7,P26196,O00429,Q9UHD2,P42858,O00330,Q05086,O14646,Q69YN2,Q13501,P42356,P28482,P40763 17 +Lethargy 0.2671273641818054 0.6149145230296051 0.5386111712232042 1.0 1.0 81 P49770,P11310,O43772,P62847,P08708,Q13144,Q96CU9,P40818 8 +Atonic seizure 0.3652686632333293 0.6147785078136528 0.5387010046632517 1.0 1.0 25 Q05639,Q01105,Q96N67,P43034,Q14353,P67870,P49419,Q08209 8 +Impaired glucose tolerance 0.4268738448056463 0.6134388421007468 0.5395862096682873 1.0 1.0 6 O00170,P40818 2 +Shortening of all distal phalanges of the fingers 0.3612733913178938 0.6109405140610554 0.5412389622144551 1.0 1.0 11 Q92796,Q93008,Q8IWS0 3 +Aminoaciduria 0.3283034145855142 0.6075062703213979 0.5435149826748211 1.0 1.0 40 Q4J6C6,P11310,P11172,Q99707,P18074 5 +Pseudobulbar paralysis 0.3921208389855926 0.6053352007047764 0.5449562970040696 1.0 1.0 8 Q14203,P54136,P08397,P42356 4 +Aplasia hypoplasia of the scapulae 0.4507478640224909 0.6033200630176133 0.5462957885797048 1.0 1.0 5 Q08AM6 1 +Somatic mutation 0.2916899309240836 0.6005281865568172 0.5481542817773299 1.0 1.0 48 P22681,P21359,O75874,P00813,O60566,O00170,Q14790,O14965,P30154,Q01844,P20585,Q9Y620,P52701,Q06124,O60333 15 +Prenatal movement abnormality 0.2412750235236326 0.6004810516311153 0.5481856852975981 1.0 1.0 60 Q4J6C6,Q9BPU6,P38935,Q8NCE2,Q70HW3,O00429,Q06210,P49419,Q08209 9 +Basal ganglia calcification 0.4073287848618094 0.5995459359697869 0.548808887327179 1.0 1.0 7 Q969U7,O00429 2 +Abnormal hair laboratory examination 0.3908377542960346 0.599445148066668 0.5488760776703459 1.0 1.0 8 P18074,Q15477 2 +Abnormal sputum 0.423524580770968 0.5991242289791219 0.5490900456986245 1.0 1.0 6 P57076 1 +Impaired tactile sensation 0.3740807400214574 0.5988903177662592 0.5492460284448886 1.0 1.0 9 Q5TAQ9 1 +Pallor 0.2569689550455369 0.5970432990399399 0.5504784725116934 1.0 1.0 54 P11413,P60866,P21359,O00170,P62847,P08708,P62854,Q9BUK6,P00374,Q9Y5L0,P62899 11 +Mixed hearing impairment 0.3736310616689365 0.5967475757496769 0.5506759235705398 1.0 1.0 9 Q9Y4X0 1 +Iron deficiency anemia 0.4491342347937457 0.5967367961323929 0.5506831216560661 1.0 1.0 5 Q9UER7 1 +Abnormal atrioventricular conduction 0.3629809467000867 0.5963943688090052 0.5509118014711591 1.0 1.0 15 O43772,Q99996 2 +Gout 0.4756851367357816 0.5954211333228625 0.5515620025529298 1.0 1.0 4 P08237 1 +Generalized hypopigmentation of hair 0.3561685361020482 0.5934006221157992 0.5529130726511124 1.0 1.0 10 Q05086,Q9BUR4 2 +Broad eyebrow 0.3600436141551064 0.5914128293334154 0.5542438464074366 1.0 1.0 13 P63241,O14802,P28482 3 +Abnormal aldolase level 0.7982089552238816 0.5866189161788037 0.5574596754556114 1.0 1.0 2 O43505 1 +Intermittent diarrhea 0.4039996300035031 0.5849053598492857 0.5586113544371352 1.0 1.0 7 Q9UER7 1 +Stridor 0.4039804403856856 0.5848212995031102 0.5586678810209631 1.0 1.0 7 P38935 1 +Bifid uvula 0.3285565161583622 0.5847220723286397 0.5587346101515314 1.0 1.0 39 Q9Y617,Q15392,Q6W2J9,Q13618,Q15436,Q9C0B1,P36871,Q15058,Q15813,O43318,Q9Y4X0,Q93008,P62266,Q6PGP7,Q92796,O43505,P78318 17 +Hyperglycemia 0.3875316468608682 0.5843528565894529 0.558982937480849 1.0 1.0 8 P40763,Q3SYG4 2 +Long ear 0.5811498642125192 0.5833101502407964 0.5596845307698628 1.0 1.0 3 Q7LBC6 1 +Abnormality of the shoulder girdle musculature 0.3430323773348853 0.5800221558109975 0.5618996769029132 1.0 1.0 34 Q14331,Q9Y487,O00429,Q06210,Q9Y5L0,O43318,Q13501,Q06124,Q14999,P46976 10 +Abnormal circulating amylase level 0.4190077704721978 0.5799817599887381 0.5619269181941373 1.0 1.0 6 P61011,Q9Y3A5,Q7Z2Z2,Q9Y697,A5YKK6 5 +Abnormality of vitamin k metabolism 0.4190077704721977 0.5799817599887375 0.5619269181941378 1.0 1.0 6 Q9UDY2,Q13043,P61011,Q9Y3A5,Q7Z2Z2 5 +Abnormal sarcomere morphology 0.7955223880597032 0.5787178942162059 0.5627795398199082 1.0 1.0 2 Q13501 1 +Abnormal z disc morphology 0.7955223880597032 0.5787178942162059 0.5627795398199082 1.0 1.0 2 Q13501 1 +Recurrent fever 0.3606005526998009 0.5777779535111182 0.5634140415955919 1.0 1.0 17 Q969U7,P28070,O95163,Q96BN8 4 +Akinesia 0.3688855251833922 0.5742898219051494 0.5657716955208394 1.0 1.0 9 Q6Y7W6,P51114,Q14203,O75165,Q04637 5 +Recurrent otitis media 0.350625684892401 0.5724239769751219 0.5670347758952106 1.0 1.0 30 Q00653,P00813,O14802,Q6W2J9,P57076,O43318,Q13432,P50851,Q06787 9 +Periventricular heterotopia 0.3523367089690519 0.5665464038246971 0.5710223973674997 1.0 1.0 11 Q06787,Q9Y6D5 2 +Hypoamylasemia 0.4412354094946542 0.564840881909867 0.5721819973331561 1.0 1.0 5 A5YKK6 1 +Abnormal neutrophil count 0.2493737768071124 0.5638261626053932 0.5728724447114715 1.0 1.0 70 P60866,P18074,O95394,P22681,P62081,P26639,P62847,P08708,P62854,P42766,P39019,P40763,P50851,P49327,P62899,P00491,Q96BN8,Q6W2J9,Q9UHD2,O00203 20 +Retinal coloboma 0.3660880234180864 0.5611879331996072 0.574669428115107 1.0 1.0 9 Q15042 1 +Organic aciduria 0.3136870718757133 0.5599220986011549 0.575532574745047 1.0 1.0 42 P11310,O75880,O43772 3 +Abnormal talus morphology 0.3569627062378887 0.5564019612438946 0.5779360984641597 1.0 1.0 21 Q08AM6,Q9Y263,Q14999 3 +Decreased serum insulin like growth factor 1 0.5729317739997715 0.5560834499582971 0.5781538083937703 1.0 1.0 3 Q9BV10 1 +Abnormal urine ph 0.3003589228448226 0.5555930779189082 0.5784890645615919 1.0 1.0 45 P11310,O75880,O43772 3 +Neoplasm of the larynx 0.4385357097735035 0.5540702705957538 0.5795307552359286 1.0 1.0 5 P42771,O96017,P52701 3 +Opportunistic infection 0.5717460296027587 0.5521929467551973 0.5808161662606928 1.0 1.0 3 P00813 1 +Gowers sign 0.34750007090945 0.550968995432042 0.5816549286956076 1.0 1.0 10 Q9BUK6,Q7Z392,Q06210 3 +Weight loss 0.2558248043017831 0.5486144979669132 0.5832700342574595 1.0 1.0 77 P11310,P21359,P60866,Q15645,P54277,Q6W2J9,Q01844,P42858,P42771,P18074,Q9UER7,P49327,P40763,Q13535,P22681 15 +Abnormal circulating nitrogen compound concentration 0.2577213758612267 0.5481899779300606 0.5835614629462555 1.0 1.0 53 P11310 1 +Intellectual disability profound 0.2947495451211044 0.5480168760204687 0.5836803151168559 1.0 1.0 46 Q05639,Q01105,O60566,P43034,Q9Y487,P26640,Q9Y3Z3,Q93008,P67870,Q92796,Q9BTW9,P31939,Q08209 13 +Coma 0.331967835252308 0.5454121484969231 0.5854700869468474 1.0 1.0 36 P11310,O43772 2 +Systemic lupus erythematosus 0.4358709864995446 0.5435075937662038 0.5867803638737912 1.0 1.0 5 P00491,P49327 2 +Adrenocorticotropin deficient adrenal insufficiency 0.5684513158562983 0.5414345973623308 0.588208065897021 1.0 1.0 3 O00170 1 +Hypergalactosemia 0.5684176938454374 0.5413252074812138 0.5882834488332152 1.0 1.0 3 Q96C23 1 +Neoplasm of the skin 0.3147860914810637 0.5411246880321844 0.5884216427190345 1.0 1.0 41 P21359,P60866,Q9H4L7,Q15126,P54277,P26639,Q9BUR4,P42771,P18074,P20585,P49327,P52701,P53602 13 +Thickened cortex of long bones 0.5678513429218592 0.5394837916718452 0.5895530778856402 1.0 1.0 3 P21359 1 +Neoplasm of the gastrointestinal tract 0.2745861663039564 0.5373515942252404 0.5910247729180824 1.0 1.0 95 P60866,P54277,P42771,Q9UER7,O96017,Q00653,P62081,O60566,P62847,P08708,P11802,P62854,P42766,P28340,P21359,Q14790,Q15645,O14965,Q9Y5L0,O00330,P08397,P20585,P49327,P52701,P62899,Q07864,Q9Y620,P06737,Q15477 29 +Central adrenal insufficiency 0.4086563938287127 0.5368638773400156 0.5913616443549718 1.0 1.0 6 O00170 1 +Overweight 0.4084574987051242 0.5360462115039853 0.5919266130710836 1.0 1.0 6 O00330,Q9HCK8 2 +Decreased methylcobalamin 0.7805970149253785 0.5355583165198002 0.5922638436118106 1.0 1.0 2 Q99707 1 +Hypocholesterolemia 0.3604713521967602 0.5352057546494614 0.5925075874443584 1.0 1.0 9 Q9Y6B6 1 +Recurrent opportunistic infections 0.7800000000000049 0.5338587902352117 0.5934392353649949 1.0 1.0 2 P00813 1 +Decreased proportion of cd3 positive t cells 0.7800000000000016 0.5338587902352023 0.5934392353650013 1.0 1.0 2 O95394 1 +Abdominal distention 0.3512675850679336 0.53375023290568 0.5935143498513917 1.0 1.0 24 O15357,Q9Y6B6,Q01844,Q9Y5L0,P08397 5 +Bilateral talipes equinovarus 0.3920926534911927 0.5335157777169913 0.593676592173022 1.0 1.0 7 Q2VPK5,Q15392,A1X283 3 +Intellectual disability progressive 0.3451785622066899 0.5318497509677921 0.5948300620690627 1.0 1.0 11 Q05086 1 +Abnormal pulmonary valve physiology 0.3237303951703687 0.5317161156028835 0.5949226285441707 1.0 1.0 38 P21359,P00813,O14802,Q6W2J9,Q86TI2,O43318,O60826,Q06124 8 +Lactose intolerance 0.5653646332455791 0.5314260087383154 0.5951236022537483 1.0 1.0 3 O95394 1 +Gastrointestinal stroma tumor 0.4320360965956712 0.5284294251359172 0.5972013189035954 1.0 1.0 5 P21359 1 +Retinopathy 0.3460625254970205 0.5283820521280336 0.5972341920119253 1.0 1.0 28 Q9Y6B6,Q15555,P11802,P42771,P07437,P18074,P49327,P40763,O95352 9 +Abnormal circulating albumin concentration 0.3342942006241072 0.5272998385226841 0.597985386385115 1.0 1.0 34 P34949,Q9BV10,Q9NUW8,Q9Y6B6,Q9Y5K6,Q9Y5L0,Q14C86,P57081,Q9Y285,Q9NSD9 10 +Disproportionate short limb short stature 0.3490762960870809 0.5222342463065283 0.6015072444240037 1.0 1.0 24 Q03164 1 +Broad based gait 0.3472357692165308 0.5215709782681053 0.6019690743304051 1.0 1.0 26 Q03164,Q05086 2 +Abnormal circulating copper concentration 0.4041815006209009 0.5185712410267842 0.6040597683818734 1.0 1.0 6 Q9Y487 1 +Recurrent skin infections 0.3472564135317744 0.5180359522796314 0.6044331853398353 1.0 1.0 15 O95394,O14802,P40763,P40818 4 +Split nail 0.4552945996104285 0.5176638695556414 0.6046928109374115 1.0 1.0 4 P18074 1 +Premature graying of hair 0.3566197651161304 0.5176498971229961 0.6047025613598835 1.0 1.0 9 Q9BUR4,Q13126 2 +Polymicrogyria 0.2533888253758019 0.5148175931634884 0.6066804902116674 1.0 1.0 78 Q05639,Q01105,Q15392,O14802,Q96C86,Q2M389,Q9Y487,Q9NUQ7,Q08J23,Q14204,P07437,Q8TD16,Q9UBB6,P67870,P42356,Q96F86,Q08209,Q15042 18 +Moderate albuminuria 0.5594871203059577 0.5125624211525979 0.6082574456170662 1.0 1.0 3 P40763 1 +Ulnar deviation of finger 0.3710730594868933 0.5111875337081014 0.6092197470497485 1.0 1.0 8 P28482,Q15042 2 +Neoplasm of the nervous system 0.2752550720981112 0.5110652957175088 0.6093053357636966 1.0 1.0 49 P28340,P21359,P60866,P54277,Q01844,Q15555,P48735,P42771,P07437,Q07864,Q9UER7,P20585,P52701,Q06124,Q9H269,O60333 16 +Multiple enchondromatosis 0.40222407128819 0.5106393688571779 0.6096036034117471 1.0 1.0 6 O75874,P48735,Q06124 3 +Striae distensae 0.3544770316115671 0.5079791632600681 0.611467956040125 1.0 1.0 9 P53618,P40818,O00170,Q15334 4 +Self injurious behavior 0.2976417894904454 0.5053927879543642 0.6132829833255327 1.0 1.0 44 Q05639,Q01105,Q6IA86,P00492,Q6W2J9,Q08209,P67870,P30566,P28482,Q06787,Q14353,O95352 12 +Postnatal growth retardation 0.2340166431088207 0.5046356950587406 0.6138147340938143 1.0 1.0 62 Q03164,O60566,Q9Y487,P27635,Q08J23,Q15813,Q08AM6,O60826,P06737,Q06124,O75179,Q14999,Q13535 13 +Abnormal subarachnoid space morphology 0.3365880036263391 0.5031491374036685 0.6148594217462842 1.0 1.0 31 Q01105,Q05639,Q9BV10,O43776,Q93008,P49419,P67870,Q92796,Q14204,Q08209 10 +Hyperammonemia 0.3276588201227534 0.5029897732883911 0.6149714622924809 1.0 1.0 35 P11310 1 +Aplasia hypoplasia involving the skeletal musculature 0.35290726350826 0.5009391484749731 0.6164139495561898 1.0 1.0 9 Q9Y487,O43505,O43318 3 +Relative macrocephaly 0.3296528990332975 0.5001165649306606 0.6169930029031319 1.0 1.0 34 P21359,Q15392,O14802,Q9BPU6,P26196,Q7Z6Z7,Q07864,Q99575,P42858,Q93008 10 +Incomitant strabismus 0.3449292198789446 0.4996149315229113 0.6173462420670972 1.0 1.0 17 Q9BPU6,P26196,Q7Z6Z7,O00429,P42858 5 +Enamel hypoplasia 0.3434180835981638 0.4995536523095178 0.6173893996054749 1.0 1.0 15 P21359,P18074,Q13535 3 +Abnormal urine carboxylic acid level 0.3445357380124318 0.4986962531117256 0.6179933846178518 1.0 1.0 24 P11310,P08397 2 +Coarctation of aorta 0.3117751719064193 0.4979842502975634 0.6184951431499053 1.0 1.0 40 P21359,P62081,P60866,O60566,Q15645,P62847,P08708,P62854,P42766,P46783,P39019,Q06124,P62899 13 +Ependymoma 0.4237825867519061 0.4964938883782726 0.6195459982575473 1.0 1.0 5 P42771,O96017,O75874 3 +Triangular shaped phalanges of the hand 0.2412150510855977 0.4963634080014155 0.6196380371095236 1.0 1.0 69 P60866,Q7Z6Z7,P62081,Q9BPU6,P26196,P62847,P08708,P62854,O43318,P42766,P39019,O15357,Q08J23,Q08AM6,P62899,Q6W2J9,P42858,Q93008,Q69YN2 19 +Parakeratosis 0.4232470314982149 0.4944469660749953 0.6209905519248311 1.0 1.0 5 Q15126 1 +Dry skin 0.3285930859228437 0.4939940636477524 0.621310371942291 1.0 1.0 34 Q9H4L7,P00813,P26639,P36507,Q9Y3Z3,P11802,Q96KP1,P42771,P18074,Q15477,P28482 11 +Abnormality of the vertebral endplates 0.3826335741468988 0.4938777181973629 0.6213925415995607 1.0 1.0 7 Q9NR45 1 +Truncal obesity 0.3434458696174972 0.4924500806782041 0.622401203156441 1.0 1.0 17 Q3SYG4,P31751,P40818 3 +Leiomyosarcoma 0.350900793085382 0.491996887309528 0.6227215439979292 1.0 1.0 9 O14965,Q9Y620,O60566 3 +Soft tissue sarcoma 0.3281662810592174 0.4915375312892041 0.6230463138225342 1.0 1.0 34 P21359,Q15392,Q15645,O14965,Q13126,P42771,Q9Y620,P49327,Q06124,P52701 10 +Excessive wrinkled skin 0.3343574307805251 0.4888911560296407 0.6249187573019563 1.0 1.0 10 Q9Y487,Q06124 2 +Thenar muscle atrophy 0.5514583403019716 0.4872233436560198 0.6261000642767254 1.0 1.0 3 O60568 1 +Status epilepticus 0.2506388088024233 0.4868821359761692 0.6263418591611407 1.0 1.0 53 Q05639,Q01105,Q15392,Q9BY32,Q9UID3,Q9Y487,Q96I59,Q9UHD2,O00429,P49589,P47897,P27708,P67870,P49419,Q14204,Q08209 16 +Amenorrhea 0.313316589932582 0.4866751011452439 0.6264885928023611 1.0 1.0 39 P49770,Q16740,Q9BUK6,Q13144 4 +Cns hypomyelination 0.3062796855367809 0.4853732364182571 0.6274116136011476 1.0 1.0 41 P49770,O14802,Q96I59,Q7Z392,Q13144,P04350,Q96KP1,Q14232,P47897,P30566,Q9BTW9,P54136,Q9NW08 13 +Anisocoria 0.4208474042402235 0.4853146456897222 0.62745316809807 1.0 1.0 5 Q96IJ6 1 +Abnormal stomach morphology 0.2590363184991706 0.4852389884916551 0.627506828451845 1.0 1.0 86 P60866,Q8NCE2,Q9NPF4,P42771,Q92796,Q9Y6D5,Q00653,O60566,P11802,O43318,Q15645,O14965,Q08AM6,P20585,P50851,P49327,P52701,P28482,P57081,P50570,Q6W2J9,Q14738,Q93008,Q9Y620,Q15477 25 +Memory impairment 0.3191002434476189 0.4846110766247839 0.6279522549778123 1.0 1.0 37 P49770,P21359,P60866,P54277,Q13144,P42858,P26358,P08397,Q13501,P49327,Q06787 11 +Abnormal facial expression 0.333177694562169 0.4842856610314531 0.6281831508056543 1.0 1.0 31 Q9Y3I1,Q6Y7W6,Q9Y263,Q14331,P50570,Q8NCE2,Q9BUK6,Q14203,Q05086,O75165,P49419,P22314,Q06787 13 +Abnormal uvula morphology 0.2943247231928652 0.4827219070424489 0.6292932062327683 1.0 1.0 44 Q9Y617,Q15392,Q6W2J9,Q13618,Q15436,Q9C0B1,P36871,Q15058,Q15813,O43318,Q9Y4X0,Q93008,P62266,Q6PGP7,Q92796,O43505,P78318 17 +Abnormality of vitamin metabolism 0.3380959549758661 0.4790482783853533 0.6319042835133908 1.0 1.0 27 P11586,P41440,Q13043,Q9Y6B6,Q99707,P46783,P41252,Q7Z2Z2,P49327,Q01968,Q9NSD9 11 +Abnormality of humoral immunity 0.2312685854482642 0.4785786334121016 0.632238421656871 1.0 1.0 62 Q00653,P00813,Q9BV10,Q14790,Q96BN8,P17812,Q9Y5L0,P18074,P50851,P49327,Q15477,O95394,P40763,P28070 14 +Abnormality of vitamin e metabolism 0.4188825814162139 0.4778854880694942 0.6327317107444592 1.0 1.0 5 P61011,Q9Y3A5,Q7Z2Z2,Q13043 4 +Abnormality of neutrophil physiology 0.4188825814162102 0.4778854880694802 0.6327317107444692 1.0 1.0 5 P61011,Q9Y3A5,Q7Z2Z2,P06744 4 +Metaphyseal chondrodysplasia 0.4188825814162 0.4778854880694418 0.6327317107444965 1.0 1.0 5 O95831,P61011,Q9Y3A5,Q7Z2Z2 4 +Limb tremor 0.3785401135771743 0.4770795449562068 0.6333054798215432 1.0 1.0 7 Q05086,P04350 2 +Fine hair 0.3404053405899427 0.4753994811583893 0.6345022642140199 1.0 1.0 18 O75182,P04080,P36507,Q08J23,P49589,P18074,Q01968,P22681 8 +Peripheral pulmonary artery stenosis 0.3314052244882458 0.4753569747319661 0.634532555851751 1.0 1.0 10 Q15477 1 +Neoplasm of the breast 0.331509450563712 0.4751715419252419 0.6346647092263895 1.0 1.0 31 P28340,P21359,O75874,Q14790,P48735,Q07864,P42771,P49327,P52701,Q13535 10 +Mild hearing impairment 0.3344286284346739 0.4742271239531748 0.6353379531629262 1.0 1.0 12 Q93008,O95394,Q92796 3 +Hypoplasia of the musculature 0.3927714625204364 0.4729656514232985 0.6362376850527871 1.0 1.0 6 Q9Y487 1 +Lipoma 0.4171440249125736 0.471348873422201 0.6373916197785929 1.0 1.0 5 Q9BUK6 1 +Severe combined immunodeficiency 0.3615146005422106 0.470371259874081 0.6380897938530805 1.0 1.0 8 P11586,O95394,P00813 3 +Nephronophthisis 0.4161838616283001 0.4677539557477918 0.6399605512768383 1.0 1.0 5 Q9NQH7,Q8TD19,Q16658 3 +Abnormality of the testis size 0.3318403194754716 0.4677274378407909 0.6399795170929794 1.0 1.0 30 P21359,P27635,O43318,P18074,Q8IWS0,Q06787,Q14999 7 +Abnormal urinary color 0.4159745805713181 0.4669718310942399 0.6405200318032034 1.0 1.0 5 P08397 1 +Tube feeding 0.2333592459466642 0.4659321554215438 0.6412640637487181 1.0 1.0 65 Q05639,O60701,Q01105,Q9BV10,Q92734,Q96C86,Q2M389,Q9NUQ7,Q08J23,O00429,Q9UBB6,P67870,Q96F86,Q08209 14 +Cerebral hypoplasia 0.3378643646697193 0.4658832701360379 0.6412990568204076 1.0 1.0 17 P42695,Q15058,Q00534,Q08AM6,Q13057 5 +Secondary microcephaly 0.2468627741956244 0.4653759638085905 0.6416622439413517 1.0 1.0 77 P49770,Q05639,Q96KP1,Q14232,Q9Y6D5,Q9Y487,P08243,Q9BTW9,Q9Y263,Q13144,Q9BSJ2,P00374,Q05086,Q01433,Q96CU9,Q9BV10,P43034,P26640,Q14746,O95630 20 +Aplasia hypoplasia of the phalanges of the hand 0.2420954314590049 0.463401498700915 0.643076604607864 1.0 1.0 54 Q03164,O43318,Q08AM6,O60826,A1X283,Q92796 6 +Impaired tandem gait 0.3367528267227132 0.4606688177775042 0.6450362299626622 1.0 1.0 17 Q9BPU6,P26196,Q7Z6Z7,P42858,Q06787 5 +Neoplasm of the respiratory system 0.3360286820703516 0.460645320506435 0.6450530907469534 1.0 1.0 16 Q14790,Q15645,P30154,Q01844,P43246,P42771,P52701,O96017,Q9UPY3 9 +Nasogastric tube feeding 0.3363456065206077 0.4606287220725584 0.6450650012874106 1.0 1.0 25 Q9Y617,P15311,Q96C86,Q2M389,Q9NUQ7,Q08J23,P49591,Q9UBB6,Q96F86 9 +Abnormality of hair pigmentation 0.337538727700901 0.4594513908449953 0.6459100511710534 1.0 1.0 22 Q9BUR4,Q13126,Q05086,Q15477,P49327 5 +Hypogonadism 0.2580478166388518 0.4573091229753039 0.6474488733215287 1.0 1.0 88 Q16740,O00170,Q15555,P18074,Q9NW08,Q06787,Q3SYG4,P22681,O14802,O00429,Q92620,Q8IWS0,Q9BW83,P28340,Q4J6C6,P20839,P48449,Q06124,Q07864,Q15042 20 +Enchondroma 0.3269543671170501 0.455258250358958 0.6489234581475987 1.0 1.0 10 O75874,Q9Y3Z3,P48735,O15160,Q06124 5 +Receptive language delay 0.3361102140939095 0.4550683827016668 0.6490600434182086 1.0 1.0 18 Q9BPU6,P26196,Q7Z6Z7,P42858,Q16512 5 +Abnormal urine phosphate concentration 0.4124427525715287 0.4538513797430054 0.6499358000464226 1.0 1.0 5 O15357 1 +Prominent metopic ridge 0.3335570625040265 0.453363190446841 0.650287237617232 1.0 1.0 15 P28482,P18074,P40763,P30566 4 +Decreased mean corpuscular volume 0.5390630630876246 0.4491368403933068 0.6533329460103112 1.0 1.0 3 Q96Q11 1 +Menorrhagia 0.5389000984187255 0.4486448459856555 0.6536878773972681 1.0 1.0 3 P40818 1 +Misalignment of incisors 0.4109327734500924 0.448287945975755 0.653945398906391 1.0 1.0 5 Q9BSJ2 1 +Acanthosis nigricans 0.3287137080934936 0.4482728018004753 0.6539563271105908 1.0 1.0 12 P28070,O14802,P31751,O00170 4 +Spastic dysarthria 0.3252012774370616 0.4474459829877193 0.654553081241865 1.0 1.0 10 O14802,Q8N0X7 2 +Moderate sensorineural hearing impairment 0.3406409721273828 0.4473066528698146 0.6546536641081737 1.0 1.0 9 Q93008,Q92796 2 +Unilateral renal agenesis 0.3350109379034965 0.4472312000048717 0.6547081363940768 1.0 1.0 22 P42695,Q00534,Q2VPK5,O75179,Q06124 5 +Aplasia hypoplasia of the ovary 0.3309730497196974 0.4464791475988665 0.6552511719865814 1.0 1.0 14 Q3SYG4,Q06124 2 +Gastrointestinal inflammation 0.3347311225132086 0.4458876930459149 0.6556783725729824 1.0 1.0 22 Q7Z392,Q9Y5L0,O43318,P50851,P49327,Q15477,O95394 7 +Micromelia 0.3342064345663184 0.4446978106530156 0.6565381517061462 1.0 1.0 23 Q15392,O15357,P48735,Q07864,Q14999 5 +Contractures of the joints of the upper limbs 0.2431609809888397 0.4424824686490873 0.6581401137770302 1.0 1.0 76 Q9H4L7,Q15392,O14802,Q92917,P38935,Q6W2J9,O43318,P18074,A1X283,Q15042,Q96AY3,P57081,O60231,Q13535 14 +Poor wound healing 0.3846552332145471 0.4415043889420249 0.6588478848417663 1.0 1.0 6 P40818 1 +Abnormal nipple morphology 0.2260167643333974 0.4408327951440909 0.6593340495436801 1.0 1.0 61 P21359,Q9BV10,P48444,P26196,P26639,Q15555,Q96KP1,P07437,Q9Y4X0,P18074,Q08AM6,O60826,Q14738,Q8IWV7,Q06124,P22681 16 +Cystic hygroma 0.3691592903772633 0.4394559404814438 0.6603312003296322 1.0 1.0 7 P22681 1 +Premature ovarian insufficiency 0.3332520556271433 0.4388170371014024 0.6607941144000145 1.0 1.0 22 P49770,P51570,Q13144,P49327,Q06787,P40818 6 +Hepatitis 0.3318188909460745 0.4378404645363414 0.6615019356763623 1.0 1.0 17 Q9Y5L0,Q15477,Q14790 3 +Abnormality of the chin 0.2447713764152507 0.4371981161735538 0.6619676758197737 1.0 1.0 78 O00170,Q9BUK6,Q06787,Q14999,O60701,O14802,P27635,O00429,Q06210,O43318,P67870,Q7LBC6,Q08J23,Q05086,Q08AM6,A1X283,Q06124,P28482,Q2VPK5 19 +Diffuse cerebral atrophy 0.331008621694448 0.4341421995464189 0.6641851830109406 1.0 1.0 17 Q14746,O00429,Q9BTW9,Q9H269,Q06787 5 +Neoplasm of the male external genitalia 0.3221020894767343 0.4337836014679407 0.6644455908324121 1.0 1.0 10 P42771,O96017,Q01844 3 +Fibrous tissue neoplasm 0.3314654625635199 0.4335321353775785 0.6646282253935556 1.0 1.0 18 P21359,Q15392,P49327,Q13126 4 +Acute myeloid leukemia 0.3128087700458472 0.4324654230090308 0.6654031775409557 1.0 1.0 36 P62081,P60866,P62847,P08708,P62854,P42771,P42766,P39019,O96017,P62899 10 +Cerebellar vermis atrophy 0.3278176052788725 0.4323006082773892 0.6655229451309532 1.0 1.0 14 Q9NUW8,Q5RI15,P42858,P07437,P47897 5 +Decreased muscle mass 0.330483246255285 0.4317520542063811 0.6659216299256072 1.0 1.0 17 Q9Y487,Q06210,O43318,Q9Y285,P46976 5 +Fetal ultrasound soft marker 0.3314377892595339 0.4298443773411432 0.6673088491333312 1.0 1.0 21 Q9BPU6,Q2TAL8,O60826,Q06124,P22681 5 +Abnormality of the calf musculature 0.3281813818418229 0.4290189302363074 0.6679094484611428 1.0 1.0 15 Q96IJ6,Q14331,Q8NCE2,Q7Z392,O60231 5 +Muscle hypertrophy of the lower extremities 0.3512954490941941 0.4282719844752135 0.6684531131836011 1.0 1.0 8 Q8NCE2,Q14331,O60231 3 +Abnormal waist to hip ratio 0.3661988862156266 0.4278478192734149 0.6687619194181866 1.0 1.0 7 P31751 1 +Osteomyelitis 0.3286907622802816 0.4271123460045863 0.669297500993733 1.0 1.0 16 P26358,P40763,Q13126 3 +Telangiectasia of the skin 0.3304020818875577 0.4264774312573469 0.6697599898345514 1.0 1.0 23 P21359,Q9BUR4,Q07864,Q9UER7,P40818 5 +Reduced antithrombin iii activity 0.4298206591197695 0.4263349254366063 0.6698638120924507 1.0 1.0 4 P34949,P36871 2 +Cutaneous syndactyly 0.3201394593912569 0.4252318459600765 0.6706676711334065 1.0 1.0 10 Q6W2J9,Q9H4L7,P27635 3 +Generalized onset seizure 0.2761098044096949 0.4232744003750407 0.6720950695674499 1.0 1.0 109 Q05639,Q2M389,P18074,Q92796,Q96F86,Q14353,Q00653,Q96N67,O60566,P26639,P27635,O00429,P67870,Q9BTW9,Q08209,P40763,Q01105,Q9Y263,O43776,Q08J23,O00330,Q05086,P00374,P28482,P43034,Q96C86,Q9NUQ7,Q14746,Q93008,Q9UBB6,P49419 31 +Abnormality of hepatobiliary system physiology 0.2442488925472968 0.4232562867636775 0.6721082838140635 1.0 1.0 79 P11310,P34949,Q9UID3,O43772,Q9BUR4,Q9UER7,P22681 7 +Protruding ear 0.2769815962085396 0.4226742113451343 0.6725329735457708 1.0 1.0 46 P21359,P10589,P26639,Q7Z6Z7,P27635,Q08J23,Q9BSJ2,P18074,Q06124,A1X283,Q14999,Q06787,P52732,O43505 14 +Hypoplastic ilia 0.3194901656596416 0.4224201054758881 0.6727184052388471 1.0 1.0 10 Q99575,O14802,O15357 3 +Peripheral axonal degeneration 0.2419420388203016 0.422379799438534 0.6727478200713901 1.0 1.0 77 P41440,Q9NX46,Q8NCE2,Q7Z392,Q15813,Q96IJ6,O60333,P38935,Q9BTW9,O60231,P40763,Q5TAQ9,O96007,O00330,P08397,Q01433,Q13057,P50570,Q92734,Q9NUW8,Q14204 21 +Abnormality of the septum pellucidum 0.2959998413761611 0.4215895518390201 0.6733246338110583 1.0 1.0 41 Q15392,Q9BV10,Q96C86,Q2M389,Q9NUQ7,P43034,Q08J23,Q14738,Q9UBB6,P28482,Q96F86 11 +Keratoconjunctivitis 0.3189957565766059 0.4202849518896417 0.6742773015778072 1.0 1.0 10 P18074,P49327 2 +Oral pharyngeal dysphagia 0.3256466517723447 0.4177568933138387 0.6761248707384371 1.0 1.0 15 Q01105,Q08209,P67870 3 +2 3 toe cutaneous syndactyly 0.5284407045965384 0.4175657342301254 0.6762646541465862 1.0 1.0 3 Q6W2J9 1 +Branchial anomaly 0.3483647707751711 0.4165134556814946 0.6770343232877294 1.0 1.0 8 O15160,P28482,P27635 3 +Ragged red muscle fibers 0.3267728618125982 0.4150493482544691 0.6781057780096664 1.0 1.0 17 Q70HW3 1 +Abnormal thyroid hormone level 0.7358208955223906 0.4144954567333518 0.6785112936410183 1.0 1.0 2 Q93008 1 +Blue irides 0.3176099240561002 0.4143273363721656 0.6786343965177648 1.0 1.0 10 P28482,Q05086 2 +Eeg with multifocal slow activity 0.3326857036470267 0.4139279412866172 0.6789268802086756 1.0 1.0 9 Q05639,Q00610,Q8NC96,P49588,P38606,Q08209 6 +Degeneration of the striatum 0.4012891403529115 0.4134334537356942 0.6792890686942963 1.0 1.0 5 Q9Y3Z3,P42858 2 +Abnormal diaphysis morphology 0.2362144293638299 0.4113480313492162 0.6808173547047942 1.0 1.0 73 P21359,O14802,Q8N0X7,O00170,O15357,Q9Y487,Q6W2J9,P36507,Q13126,Q15813,O43318,Q08AM6,A1X283,Q96AY3,P28482,Q06124 16 +Generalized joint laxity 0.3212972583491853 0.4092836728397895 0.6823314960045179 1.0 1.0 13 Q9BUK6 1 +Fragile nails 0.3181292462484229 0.4089113345657545 0.6826047306787923 1.0 1.0 11 O75182,Q9Y487,P18074 3 +Abnormal fingertip morphology 0.3216220238164044 0.4076996198307933 0.6834942166067011 1.0 1.0 29 Q9BPU6,P26196,Q6W2J9,Q7Z6Z7,Q86TI2,P42858,O14646,P50851,Q8N806 9 +Abnormality of t cell physiology 0.3222120697623803 0.4076413667310717 0.683536989661212 1.0 1.0 14 P11172,P00813,Q14790,P17812 4 +Birth length less than 3rd percentile 0.4242344652865147 0.4073012497277337 0.6837867450254422 1.0 1.0 4 Q15813 1 +Abnormality of the elbow 0.2276046799818111 0.4047246761497355 0.6856799016337503 1.0 1.0 66 P21359,Q03164,Q6W2J9,P36507,O43318,Q06124,Q13535,Q96AY3,Q14999,P22681 10 +Prematurely aged appearance 0.2962652829243778 0.4038024644391828 0.6863579841044642 1.0 1.0 40 O14802,Q9Y487,Q9BUR4,Q13126,P18074,P49327,Q06124,Q15042,Q13535 9 +Eeg with focal epileptiform discharges 0.2991878084690425 0.4028547424156081 0.6870550868911511 1.0 1.0 39 Q96N67,Q96C86,Q2M389,Q9NUQ7,Q05086,Q9UBB6,P49419,P42356,Q96F86,Q08209 10 +Abnormal vestibulo ocular reflex 0.7307462686567214 0.4016639180008822 0.6879313824633262 1.0 1.0 2 P41440 1 +Hypermethioninemia 0.3974701995201563 0.3999674914238849 0.6891804608107983 1.0 1.0 5 P23526,P16930,Q6PGP7 3 +Decreased facial expression 0.3242424394229892 0.39939009482421 0.6896057912815599 1.0 1.0 24 Q9Y3I1,Q6Y7W6,Q9Y263,Q14331,Q9BUK6,Q14203,Q05086,O75165,Q04637,P22314,Q06787 11 +Focal dystonia 0.3236658332539263 0.3991480333138936 0.6897841314207642 1.0 1.0 25 Q9H269,Q9NQZ5,Q08AM6 3 +Limb pain 0.3430293617604334 0.3954869770597048 0.6924835307480899 1.0 1.0 8 O75569 1 +Cns demyelination 0.31778530817062 0.3942446858626023 0.6934003971524085 1.0 1.0 13 P49770 1 +Uncombable hair 0.7262686567164243 0.390505129213156 0.6961630632250304 1.0 1.0 2 Q15477 1 +Impaired visuospatial constructive cognition 0.3416865861268614 0.3902746400213318 0.696333473768223 1.0 1.0 8 P21359 1 +Deformed rib cage 0.4187574671445471 0.3890195044328072 0.6972617181639966 1.0 1.0 4 P61011,Q9Y3A5,Q7Z2Z2 3 +Reduction of neutrophil motility 0.4187574671445471 0.3890195044328072 0.6972617181639966 1.0 1.0 4 P61011,Q9Y3A5,Q7Z2Z2 3 +Congenital hip dislocation 0.3198559167914518 0.3884396098286014 0.6976907365051601 1.0 1.0 27 P43034,Q9Y487,Q14738,O43318,Q93008,Q9BTW9,Q14999 7 +Wrist flexion contracture 0.3702417358447948 0.38785274777629 0.6981250079097034 1.0 1.0 6 O43318 1 +Chorea 0.2493305033103362 0.3849054383471998 0.7003074765368742 1.0 1.0 88 Q05639,Q2M389,Q7Z392,Q9P0J0,P18074,Q96F86,Q14353,Q9BPU6,P00492,P67870,Q08209,Q01105,Q6IA86,P04350,O95352,Q9BWD1,Q96C86,Q9NUQ7,P42858,Q9UBB6 20 +Telangiectasia 0.3040173124645198 0.3847133555252414 0.700449799114325 1.0 1.0 36 P28340,P21359,Q9BUR4,Q07864,Q9UER7,Q13535,P40818 7 +Multifocal epileptiform discharges 0.3168919889074694 0.384664210803743 0.700486214281278 1.0 1.0 29 Q96N67,Q96C86,Q2M389,Q9NUQ7,Q9UBB6,P49419,Q96F86,Q08209 8 +Dyslexia 0.3254561770864455 0.38463681030193 0.7005065177545238 1.0 1.0 9 P11166,P55072,P48506,Q9UQN3,Q13501,P46821,Q9H6K4,Q01082 8 +Abnormality of immune serum protein physiology 0.3546527305404282 0.3838769210766255 0.7010696725984333 1.0 1.0 7 Q9Y3Z3,P49327 2 +Hypoplasia of the ear cartilage 0.3923696997439863 0.3822948122110836 0.7022427022524778 1.0 1.0 5 P57081 1 +Aplasia hypoplasia involving bones of the feet 0.2304800775060689 0.3819907121800127 0.7024682538159321 1.0 1.0 71 Q03164,P00813,Q9BPU6,Q8N0X7,P42858,Q15813,Q08AM6,Q06787 8 +Atrioventricular canal defect 0.3375712461663573 0.374504774474084 0.7080288051092796 1.0 1.0 8 O60826 1 +Macrodontia 0.3189111607072409 0.3740646986416417 0.7083561817016684 1.0 1.0 20 Q9BPU6,Q9UID3,P26196,Q7Z6Z7,P42858 5 +Septate vagina 0.5126061261893529 0.3724816648503751 0.709534260824896 1.0 1.0 3 Q6W2J9 1 +Hamartoma 0.3181553333151418 0.3723566736948447 0.7096273077193043 1.0 1.0 19 P21359,O75874,P48735,P20585,P52701,Q9H269,O60333 7 +Immunologic hypersensitivity 0.3016523180416987 0.3723520282625621 0.7096307659918426 1.0 1.0 36 Q00653,P00813,Q14790,Q9UID3,Q08J23,Q9Y5L0,P18074,P50851,P49327,O95394,P40763,P22681 12 +Delayed gross motor development 0.2784664457709505 0.3718204579769951 0.7100265307462093 1.0 1.0 118 Q03164,Q9P2J5,Q9UID3,Q8NCE2,Q7Z6Z7,Q16512,O60701,Q9BPU6,P26196,P27635,Q96D71,P67870,Q01105,Q7LBC6,O43776,Q9Y5L0,Q05086,Q01433,P48449,P57081,O95352,P53618,Q9BV10,P50570,P43034,Q15058,P42858,Q14738,P49589,Q9UBB6,Q14204,Q15042 32 +Abnormal ovarian physiology 0.3150998591499209 0.3707743210005653 0.7108056291207321 1.0 1.0 28 P49770,O00170,Q13144,Q06787,P40818 5 +Holoprosencephaly 0.310457818519222 0.3699403697392388 0.7114269211958788 1.0 1.0 12 Q92917,O60566,Q15645,O43684,A5YKK6,O43683 6 +Narrow nose 0.365162790275388 0.3696773812376983 0.7116228868977601 1.0 1.0 6 Q07864 1 +Mild microcephaly 0.3358040461381412 0.3678295599030213 0.713000326274678 1.0 1.0 8 Q05086 1 +Albinism 0.7158208955223913 0.3650793471124544 0.7150521771018354 1.0 1.0 2 O00203 1 +Pulmonary artery dilatation 0.3132490131495011 0.3647990777283401 0.7152613935926189 1.0 1.0 15 P26196,Q7Z6Z7,Q9BPU6,P42858 4 +Bulbar signs 0.3074808656828001 0.3646364965973346 0.7153827675406124 1.0 1.0 11 Q9Y263 1 +Synostosis involving digits 0.5096439100618075 0.3643253546183499 0.7156150687401164 1.0 1.0 3 Q9H1A4 1 +Vertebral wedging 0.509248103298311 0.3632423742451509 0.7164238361553941 1.0 1.0 3 Q96AY3 1 +Abnormal rectum morphology 0.3078727610397348 0.3625291850410455 0.7169566181544142 1.0 1.0 32 P28340,P60866,P54277,Q6W2J9,Q08J23,Q07864,Q15056,P42771,O15160,P20585,Q8IWV7,P52701,O96017 13 +Ovarian neoplasm 0.3161616998917418 0.3611173337086443 0.7180117359175471 1.0 1.0 22 O75874,P54277,Q01844,P48735,P43246,P42771,P20585,P52701,O96017,Q9UPY3 10 +Large beaked nose 0.3339971166834084 0.3610655043159901 0.7180504797877476 1.0 1.0 8 P18074,O14802 2 +Symptomatic seizures 0.333859172774499 0.3605516925490627 0.7184346071620948 1.0 1.0 8 P31751 1 +Dermal atrophy 0.3151435657277809 0.3602844354577509 0.7186344375883669 1.0 1.0 25 P28340,Q15392,O00170,P40818 4 +Mild global developmental delay 0.3139403916960186 0.359801377959111 0.7189956726486406 1.0 1.0 17 Q99741,P33991,O00203,P41252,Q01968,Q13535 6 +Increased adipose tissue 0.4097022739295697 0.3596577997032586 0.7191030539626126 1.0 1.0 4 P31751 1 +Central primitive neuroectodermal tumor 0.4094218267881815 0.358766188194635 0.7197700089106538 1.0 1.0 4 P42771,O96017 2 +Juvenile aseptic necrosis 0.3849531989142278 0.3572599012128895 0.7208972459774263 1.0 1.0 5 Q8IWS0,Q9NUQ7 2 +Interictal eeg abnormality 0.2444467351323019 0.3552439522703149 0.7224068400757622 1.0 1.0 87 Q05639,Q2M389,Q96F86,Q9Y6D5,O60701,Q96N67,Q9NQZ5,P27635,P08243,Q08209,P21359,Q9Y263,Q08J23,Q9BSJ2,Q05086,Q96C86,Q9NUQ7,Q9UBB6,P49419,P42356 20 +Ulcerative colitis 0.711641791044781 0.3551547413071886 0.7224736685530313 1.0 1.0 2 O43318 1 +Abnormal lateral ventricle morphology 0.3074953886144204 0.3531164767728872 0.7240011208902928 1.0 1.0 31 Q01105,Q9UID3,P36507,Q14738,P67870,Q08209,Q15042 7 +Peripheral cyanosis 0.3457811320264775 0.3515925808171576 0.7251438300397812 1.0 1.0 7 O95163,O75792,Q9Y3Z3 3 +Delayed menarche 0.359849640101189 0.3510975579425595 0.7255151599570522 1.0 1.0 6 O00429 1 +Ankle clonus 0.3057805876631908 0.3510913031182405 0.7255198522813933 1.0 1.0 12 Q8N0X7,P42858 2 +Broad forehead 0.2693171882211328 0.3492546885627882 0.72689811240251 1.0 1.0 45 P21359,O00170,Q07864,Q9Y4X0,A1X283,Q15477,Q16512,Q14999 8 +Acute leukemia 0.2523616975120877 0.3480570904437243 0.7277973087280212 1.0 1.0 49 P62081,P60866,O60566,Q15645,P62847,O43684,P08708,P62854,Q08J23,P42771,P11766,P42766,Q7Z2Z2,P46783,P39019,O96017,P62899,O43683 18 +Peripheral axonal neuropathy 0.2128358197632415 0.347524543695417 0.7281972829478998 1.0 1.0 59 Q96IJ6,P50570,Q5TAQ9,Q8NCE2,Q7Z392,Q9NUW8,Q14204,Q15813,O00330,P08397,Q01433,Q9BTW9,Q13057,P40763,O60231 15 +Slender build 0.3030508734955616 0.3469918330676526 0.7285974543164477 1.0 1.0 11 O14802,Q9NSD9 2 +Gray matter heterotopia 0.3086468396969546 0.3461814132862972 0.729206382199219 1.0 1.0 29 P43034,P42695,Q15058,Q9BSJ2,Q00534,O60231,Q06787,Q9Y6D5,O43505 9 +Smooth philtrum 0.2281754370088515 0.3460700003286294 0.729290108301305 1.0 1.0 73 Q7Z6Z7,Q96KP1,O60701,Q9BPU6,Q9Y487,P26196,P27635,P67870,P29372,Q8N806,Q9Y263,Q2TAL8,Q08J23,Q9BSJ2,P28482,O95352,O00203,P42858,Q93008,P30566,O75179 21 +Nonspherocytic hemolytic anemia 0.5023583810112732 0.3446544051809957 0.7303541994890073 1.0 1.0 3 P04075 1 +Increased urinary non proteinogenic amino acid level 0.3800418285031381 0.341130733528815 0.7330051653853167 1.0 1.0 5 P32929,P30038,O00469,P51649 4 +Severe infection 0.3284220347675755 0.3405948117239926 0.7334086358090801 1.0 1.0 8 P17812 1 +Abnormal circulating creatinine concentration 0.3565582190796958 0.3398174185347749 0.7339940296084682 1.0 1.0 6 P00492 1 +Spinal cord tumor 0.7032835820895588 0.3357387741112971 0.7370678637739201 1.0 1.0 2 P21359 1 +Poor coordination 0.2997696294868681 0.3342301366657024 0.738205904542742 1.0 1.0 11 P49589,Q99707 2 +Abnormality of the periorbital region 0.2296395181614152 0.3323944987107189 0.7395913920277861 1.0 1.0 76 O00170,Q14331,Q15056,Q96KP1,Q92796,Q9HCK8,Q96N67,P36507,O43318,Q8IWS0,P28070,Q08J23,P07437,O14646,Q9UET6,P57081,Q9Y5K6,Q93008,P62266,O75179,Q14C86,P52732 22 +Widened cerebral subarachnoid space 0.4975896832201356 0.3320860102472321 0.7398243134836926 1.0 1.0 3 Q9BV10 1 +Prominent digit pad 0.3082362954263458 0.3294044891261448 0.7418499751306566 1.0 1.0 20 Q9BPU6,P26196,Q6W2J9,Q7Z6Z7,P42858,Q8N806 6 +Ambiguous genitalia 0.3084484585722378 0.3286451782789025 0.7424238958098999 1.0 1.0 22 Q9Y617,Q15392,O60566,Q15645,Q2VPK5 5 +Alkalosis 0.3530889206435483 0.3281232681331092 0.7428184616323852 1.0 1.0 6 P40818 1 +Focal motor seizure 0.3082167614911798 0.3276963294800458 0.7431412789411822 1.0 1.0 22 Q01105,Q05639,P43034,P67870,P49419,Q08209 6 +Shield chest 0.3991490028439611 0.3268711520320341 0.7437653409585552 1.0 1.0 4 Q06124 1 +Mildly elevated creatine kinase 0.3078649109422869 0.3264133853220286 0.7441116116246715 1.0 1.0 23 Q92734,Q8NCE2,Q2TAL8,Q06210,Q9BUK6 5 +Neuronal loss in the cerebral cortex 0.3515806397577867 0.3231029724798969 0.7466172591864995 1.0 1.0 6 Q13501 1 +Narrow iliac wing 0.3978583153361323 0.3229715557720671 0.7467167838372886 1.0 1.0 4 Q9NR45 1 +Abnormal internal genitalia 0.279233132016313 0.3228009574413477 0.7468459878603568 1.0 1.0 126 Q16740,P49770,P60866,O00170,P54277,Q9BUR4,P42771,P18074,Q06787,Q3SYG4,O75874,O60566,P26639,P48735,Q8IWV7,Q8IWS0,P40818,P28340,Q15645,O14965,P31751,Q13144,P20585,P49327,Q06124,P52701,Q6W2J9,Q01844,Q07864,Q15058,Q9Y620 31 +Schistocytosis 0.3742339000886554 0.3225376568304656 0.7470454146680898 1.0 1.0 5 P41440 1 +Cerebral palsy 0.296607181137954 0.3221845428041419 0.7473128937403897 1.0 1.0 11 O75874,P48735,O00170 3 +Long thorax 0.6970149253731406 0.3215641218592215 0.7477829278572588 1.0 1.0 2 Q6W2J9 1 +Abnormal midbrain morphology 0.3227684146553872 0.3204703932091262 0.748611770631814 1.0 1.0 8 Q15813,Q96KP1 2 +Abnormal circulating hormone concentration 0.2455808015637381 0.3175715806193672 0.7508099343519175 1.0 1.0 93 P49770,P21359,Q03164,P34949,Q9BV10,Q4J6C6,O00170,Q00653,P31751,Q13144,Q07864,Q15555,Q15813,Q9UER7,Q06787,P57081,P40818 17 +Absent septum pellucidum 0.2981227597422887 0.3171558903164779 0.7511253178300765 1.0 1.0 32 Q9Y617,Q15392,P15311,Q96C86,Q2M389,Q9NUQ7,Q08J23,Q9UBB6,Q96F86,O43505 10 +Disproportionate short stature 0.3017433185181778 0.3156806007569623 0.7522449526681996 1.0 1.0 29 Q03164 1 +Abnormal size of the palpebral fissures 0.2431318387174201 0.3149470536266991 0.7528018545512016 1.0 1.0 91 Q03164,Q7Z6Z7,Q15555,Q92796,O95394,O60701,Q9BPU6,P26196,P27635,P36507,Q8IWS0,Q92917,Q08J23,P07437,P63241,P28482,Q13535,Q6W2J9,P42858 19 +Abnormal cartilage morphology 0.2957041426009532 0.3123245267223408 0.754793902052322 1.0 1.0 12 P22314,O75874,P48735,Q06124 4 +Impaired vibratory sensation 0.3003727911592794 0.3098192303576836 0.7566984269713017 1.0 1.0 29 O15020,O14802,Q8N0X7,Q5TAQ9,Q9Y6B6,Q00796,Q06787 7 +Abnormality of the uterus 0.2079050255462714 0.3091431525107397 0.7572126348175345 1.0 1.0 59 Q16740,P28340,P60866,O14965,Q07864,P20585,Q9Y620 7 +Abnormality of vitamin b metabolism 0.297655583071461 0.3083806875512539 0.7577926754844557 1.0 1.0 14 P41440,Q99707 2 +Abnormality of the pulmonary artery 0.2901146784246517 0.3053325971552455 0.7601128515939857 1.0 1.0 35 Q9BPU6,P26196,Q6W2J9,Q7Z6Z7,P42858,Q15477,Q06124,P22681 8 +Abnormal forearm bone morphology 0.3025184726501371 0.3048633201670955 0.7604702529668703 1.0 1.0 22 Q14999,Q13535 2 +Micropenis 0.2160462249109993 0.304165229954385 0.7610020130925377 1.0 1.0 67 Q9BPU6,O60566,Q9BV10,P48444,P26196,Q7Z6Z7,Q9Y3Z3,Q07864,Q15813,P18074,Q08AM6,Q06124,P48449,Q8IWV7,Q8IWS0,P22314,Q2VPK5,O43505 18 +Adrenocortical carcinoma 0.39149151783666 0.3040989353215106 0.7610525179453591 1.0 1.0 4 P42771 1 +Prominent supraorbital ridges 0.2950423685719557 0.304011092169936 0.7611194405486614 1.0 1.0 13 O43318,Q9HCK8,P36507,Q8IWS0 4 +Csf pleocytosis 0.3671244007288565 0.3005120504677313 0.763786606018509 1.0 1.0 5 Q9UHD2,Q9Y3Z3 2 +Csf lymphocytic pleiocytosis 0.3671244007288565 0.3005120504677313 0.763786606018509 1.0 1.0 5 Q9UHD2,Q9Y3Z3 2 +Abnormal right ventricle morphology 0.3169007825133809 0.3002858149060309 0.7639591523262108 1.0 1.0 8 O95630 1 +Cutaneous abscess 0.6868656716417949 0.299337230093846 0.7646827505807066 1.0 1.0 2 O95394 1 +Abnormality of tibia morphology 0.2944697785558006 0.2966390467613445 0.7667420969013434 1.0 1.0 14 Q32P28,P21359,Q9BV10,P26196 4 +Abnormal elasticity of skin 0.2128212345917656 0.296626119883593 0.7667519671188765 1.0 1.0 65 P28340,Q9H4L7,Q9BV10,O00170,Q9Y487,P36507,Q15555,Q13126,Q08AM6,A1X283,Q06124,P40818 12 +Goiter 0.315772575553536 0.2964888554154453 0.7668567766762759 1.0 1.0 8 O75874,P48735 2 +Tachycardia 0.2992343992223337 0.2953446009863605 0.7677306485722677 1.0 1.0 26 Q99996,O43772,O95163,P08397,O60333 5 +Subglottic stenosis 0.4829289191080486 0.2950294959674674 0.7679713475080316 1.0 1.0 3 O43318 1 +Patellar hypoplasia 0.6844776119403024 0.2942395947820854 0.7685748267970247 1.0 1.0 2 Q8N806 1 +Pterygium 0.2885123656198337 0.2925245204674591 0.7698856147291411 1.0 1.0 11 O15111,P18074,Q96AY3 3 +Ectopic anus 0.2923276317909019 0.2889001422219594 0.7726577948880013 1.0 1.0 14 O60826,Q8IWV7 2 +Dental malocclusion 0.296597837100144 0.2872292409960734 0.7739367981135052 1.0 1.0 27 Q6W2J9,A1X283,Q06210,Q13535 4 +Abnormal circulating ceruloplasmin concentration 0.680000000000004 0.2848193848285747 0.7757825201259017 1.0 1.0 2 Q14746 1 +Intellectual disability moderate 0.2240525100650997 0.2847381448210832 0.7758447644283102 1.0 1.0 77 Q05639,Q2M389,Q92796,Q06787,Q96F86,O95394,O14802,P00492,P67870,Q9BTW9,Q08209,Q01105,Q4J6C6,Q08J23,Q9H269,Q96C86,Q9NUQ7,Q14738,Q93008,Q69YN2,Q9UBB6 21 +Leukocytosis 0.2940541656571464 0.2836518715001814 0.7766771812861146 1.0 1.0 29 P11413,P00813,Q96BN8,Q6W2J9,Q9UHD2,P49327,P40763,P22681 8 +Abnormal platelet function 0.3611870880168278 0.2827590562598003 0.7773615423237861 1.0 1.0 5 P22681,Q06124 2 +Abnormal granulocyte count 0.224690334938994 0.2818800753304304 0.7780354678777408 1.0 1.0 78 P60866,P00813,P18074,O95394,P22681,P62081,P26639,P62847,P08708,P62854,P42766,P39019,P40763,P50851,P49327,P62899,P00491,Q96BN8,Q6W2J9,Q9UHD2,O00203 21 +Abnormal dermatoglyphics 0.2214985055619052 0.2818268539611976 0.7780762787267228 1.0 1.0 75 Q9H4L7,Q9Y263,Q92917,O00170,Q9UID3,Q9Y487,Q6W2J9,P36507,O43318,Q08AM6,Q06124,Q15042,Q13535,P22681 14 +Incisor macrodontia 0.2934264240090097 0.280415613238782 0.7791586597432236 1.0 1.0 17 P26196,Q7Z6Z7,Q9BPU6,P42858 4 +Thin upper lip vermilion 0.2498991458032323 0.2786288113141595 0.780529699747109 1.0 1.0 103 Q03164,Q9UID3,P42695,Q7Z6Z7,Q96KP1,Q92796,O14802,Q9Y4X0,P29372,P31939,Q7LBC6,Q2TAL8,Q9BSJ2,P63241,A1X283,P28482,Q9BV10,Q96C86,Q15058,Q14738,Q00534,P30566,O75179 23 +Progressive microcephaly 0.2633299623306269 0.2785001562089325 0.7806284451433079 1.0 1.0 43 Q9Y263,Q9BV10,Q9Y487,Q9BSJ2,Q01433,P08243,Q9Y6D5 7 +Papule 0.2918608303013349 0.278436412754715 0.7806773708449468 1.0 1.0 16 P21359,P40763,Q92990 3 +Irregular epiphyses 0.337585207624318 0.2784345640063006 0.7806787898477365 1.0 1.0 6 Q9NR45 1 +Confusion 0.293471839094584 0.2775141999982099 0.7813853038273173 1.0 1.0 18 O14802,P26358,P08397,P18074,P49327 5 +Abnormal metabolism 0.2444694767431671 0.2755681953350927 0.7828797405543759 1.0 1.0 48 P41440,P34949,P36543,Q96C23,P18074,Q7Z2Z2,P27708,Q9Y487,Q9Y6B6,P41252,Q9NSD9,Q13043,Q99707,P36871,P49327,P11586,Q14746,P46783,Q01968 19 +Hypoglycorrhachia 0.6752238805970191 0.2749712811199273 0.783338302473215 1.0 1.0 2 Q9UHD2 1 +Spontaneous hemolytic crises 0.6752238805970192 0.2749712811199271 0.7833383024732152 1.0 1.0 2 P06744 1 +Abnormally ossified vertebrae 0.3582312518673431 0.2741444252697341 0.7839736346587833 1.0 1.0 5 O75369,Q96EX3,Q14739,O15357 4 +Increased muscle fatiguability 0.380389010146745 0.2726809622449322 0.7850984702413579 1.0 1.0 4 Q7Z392 1 +Exercise induced muscle fatigue 0.380389010146745 0.2726809622449322 0.7850984702413579 1.0 1.0 4 Q7Z392 1 +Nephrolithiasis 0.2939510452620921 0.2723486970084749 0.7853539159845977 1.0 1.0 24 Q4J6C6,O00170,O96007,P07741,P40818 5 +Autoimmunity 0.2825465421133186 0.2719942744026655 0.7856264218086473 1.0 1.0 35 P00813,P53621,P53992,O00192,P14174,Q9Y3Z3,P22314,Q13546,Q06787,O95394,Q00653,P40763,P29144,Q13043,Q9Y5L0,P50851,P49327,P11586,P00491,O75792,Q969U7 21 +Chronic diarrhea 0.2930802683758768 0.2715910001321558 0.7859365202887219 1.0 1.0 20 P00813,Q14790,Q96BN8,Q14738,P18074,P50851 6 +Upper limb undergrowth 0.2934323492387395 0.2714090440760774 0.7860764468500281 1.0 1.0 21 Q14999,Q13535 2 +Choriocarcinoma 0.3795094758405696 0.2702754584838118 0.7869483443000269 1.0 1.0 4 P42771 1 +Insulin resistant diabetes mellitus 0.2936739583467762 0.2691993543748657 0.78777627707378 1.0 1.0 9 P40763,P31751 2 +Dyscalculia 0.2835518574852935 0.2691176604416894 0.7878391405441534 1.0 1.0 12 Q06787,Q13501 2 +Mandibular aplasia 0.3790277446075609 0.2689632189093205 0.7879579870579754 1.0 1.0 4 O15111 1 +Abnormality of the pylorus 0.2752872335281795 0.268526022193697 0.7882944473194433 1.0 1.0 38 Q00653,P50570,Q8NCE2,Q6W2J9,Q14738,O43318,Q93008,Q9UET6,Q08AM6,Q92796,P28482,Q9Y6D5 12 +Abnormality of the clitoris 0.2910188687655891 0.2636546030136897 0.7920460795573665 1.0 1.0 26 Q08AM6,P31939,Q15042,Q13535 4 +Aplasia hypoplasia of the femur 0.2900533685714915 0.2628991664141477 0.792628298825333 1.0 1.0 19 Q9NR45,Q9Y4X0,Q9BV10 3 +Persistence of primary teeth 0.3188776226787992 0.2626097940039304 0.7928513504311483 1.0 1.0 7 Q6W2J9 1 +Radial deviation of the hand or of fingers of the hand 0.2792879880156663 0.2608647868308073 0.7941967808702008 1.0 1.0 11 Q6W2J9 1 +Lipodystrophy 0.2795936999812605 0.2596458773563984 0.7951369445948442 1.0 1.0 35 P28340,Q96BN8,Q9Y487,P31751,P28070,P40818 6 +Onion bulb formation 0.278422955817189 0.2580163719857279 0.7963942719026342 1.0 1.0 11 Q5TAQ9,O60333 2 +Abnormal hair whorl 0.2898955377617321 0.2574123857481907 0.7968604425181196 1.0 1.0 23 Q9BPU6,Q7Z6Z7,P42858,Q8IWV7,O95630 5 +Myalgia 0.2589220118527112 0.257267928558415 0.7969719486816231 1.0 1.0 43 P11310,Q96BN8,Q8NCE2,O00429,Q9BUK6,Q06787 6 +Nonimmune hydrops fetalis 0.2862114210568734 0.2568630866099631 0.7972844672991806 1.0 1.0 30 P62081,P60866,P62847,P08708,P62854,P42766,P39019,P62899 8 +Myopathic facies 0.3518517029927573 0.2560701132372624 0.7978966989391485 1.0 1.0 5 Q9BUK6 1 +Decreased circulating antibody level 0.2445947663123221 0.255452309797944 0.7983737731615701 1.0 1.0 47 Q00653,P00813,Q9BV10,Q14790,P17812,P18074,P49327,Q15477,P40763 9 +Hypoplasia of the radius 0.2752285555673668 0.2539953100619169 0.799499181346623 1.0 1.0 10 Q13535 1 +Abnormal leukocyte physiology 0.2095922586298692 0.252410206099438 0.8007240121658126 1.0 1.0 68 Q00653,P11172,P00813,Q9BV10,Q14790,Q96BN8,P17812,Q9Y5L0,P18074,P50851,P49327,Q15477,O95394,P40763,P28070 15 +Loss of ability to walk 0.2807795920891773 0.249408124311584 0.8030451013888251 1.0 1.0 14 Q08AM6 1 +Low hanging columella 0.2871239105925999 0.2483855406646602 0.8038361199877944 1.0 1.0 9 Q9BTW9 1 +Delusions 0.2845557787544359 0.2467659539545396 0.8050893605781249 1.0 1.0 18 P49770,P08397,Q13144 3 +Aplasia hypoplasia of the capital femoral epiphysis 0.3266674104690912 0.2461085631488548 0.8055981944818555 1.0 1.0 6 O60568,O00443 2 +Poor fine motor coordination 0.2859610539992556 0.244804112970144 0.8066081091161492 1.0 1.0 9 Q06787,P42858 2 +Impaired proprioception 0.2665403477766601 0.2413451573814925 0.809287614527997 1.0 1.0 39 O15020,P41440,O14802,Q8N0X7,Q5TAQ9,Q9Y6B6,Q00796,Q06787 8 +Fibular hypoplasia 0.3115617310210873 0.2409357596000064 0.8096049062263004 1.0 1.0 7 Q13535 1 +Convex nasal ridge 0.2845244715467252 0.2393904333092892 0.8108028474980722 1.0 1.0 22 P28340,O14802,Q15813,P18074,Q13535 5 +Recurrent bacterial infections 0.2842945270379863 0.2386213647341717 0.8113991969680039 1.0 1.0 22 P00491,P00813,Q13043,P57076,O00203,Q15813,Q7Z2Z2,O95394,P40763 9 +Delayed ability to sit 0.280961980854101 0.2380790550339098 0.8118197793882171 1.0 1.0 17 Q9UID3,O60701,O43776,Q9BPU6 4 +Abnormality of the metopic suture 0.2809442745772135 0.2380222525860132 0.8118638350560339 1.0 1.0 17 P28482,P18074,P40763,P30566 4 +Anarthria 0.3237538887347986 0.237872349305395 0.8119801020801443 1.0 1.0 6 Q15813 1 +Flat face 0.2830303582131285 0.2366056225681775 0.8129627578701619 1.0 1.0 27 Q9Y4X0,Q03164 2 +Hand muscle weakness 0.269312295403514 0.2353636836080481 0.8139264706685831 1.0 1.0 10 Q14203,Q8TD16,Q13501,P41250 4 +Portal fibrosis 0.3654497826598938 0.2335440981747963 0.8153389307104888 1.0 1.0 4 Q9H3U1,P06737 2 +Transient neutropenia 0.3432925007469343 0.2329617498036364 0.8157911078548017 1.0 1.0 5 P61011,Q9Y3A5,Q7Z2Z2,Q5F1R6 4 +Dysgraphia 0.276983724422598 0.2328997195519971 0.8158392762198767 1.0 1.0 15 P54277,P60866,Q13501 3 +Tracheomalacia 0.2702783597725249 0.2322374626200139 0.8163535820818639 1.0 1.0 11 Q9H2M9,Q9Y4A5,Q96L58,Q9H7D7,O75369,Q93008,Q8N766,P19367,P46777,P63000 10 +Spastic paraparetic gait 0.3427254777530058 0.2314779780265035 0.8169434918914842 1.0 1.0 5 Q01433 1 +Skin appendage neoplasm 0.4544613028708434 0.2303218583925164 0.8178416766054628 1.0 1.0 3 Q9UPY3 1 +Athetosis 0.2768715790574616 0.2286522134925833 0.8191392389135252 1.0 1.0 16 Q96CU9,Q9BPU6 2 +Triangular mouth 0.3202335036322368 0.2281452305516148 0.8195333382517975 1.0 1.0 6 P18074 1 +Reduced factor xiii activity 0.6507462686567224 0.2278209116077548 0.819785469033796 1.0 1.0 2 Q06124 1 +Reduced factor xii activity 0.6507462686567224 0.2278209116077548 0.819785469033796 1.0 1.0 2 Q06124 1 +Amegakaryocytic thrombocytopenia 0.6507462686567224 0.2278209116077548 0.819785469033796 1.0 1.0 2 Q06124 1 +Abnormality of the breast 0.2489719895292262 0.2276444292599889 0.8199226770883523 1.0 1.0 111 O00170,Q15555,Q96KP1,P42771,P18074,O60826,Q06787,P22681,O75874,O14802,P26196,P26639,P11802,P48735,Q9Y4X0,Q8IWV7,Q8IWS0,P28340,P21359,Q14790,P31751,P07437,Q08AM6,A1X283,P49327,Q06124,P52701,Q13535,P48444,Q9BV10,Q07864,Q14738 32 +Aplasia hypoplasia of the hallux 0.2804016319748524 0.2258671146196339 0.8213047756329821 1.0 1.0 22 Q08AM6,Q7Z6Z7,Q9BPU6,P42858 4 +Emg myopathic abnormalities 0.2772634151898298 0.2242049735449996 0.8225978136516152 1.0 1.0 30 P04075,P50570,Q8NCE2,Q9Y6B6,Q9BUK6,Q9Y5L0,Q13501,O60231,P46976 9 +Cystic renal dysplasia 0.648358208955229 0.2235240122968478 0.8231276967290571 1.0 1.0 2 Q8TD19 1 +High forehead 0.2325750094169582 0.2234901748571721 0.823154029094533 1.0 1.0 95 Q05639,Q03164,Q9BPU6,O60566,Q15645,Q7Z6Z7,P36507,P42858,P49589,Q15813,Q08AM6,P57081,A1X283,Q06124,P28482,Q08209,P22681 17 +Maturity onset diabetes of the young 0.6477611940298558 0.2224583177335547 0.8239571179307954 1.0 1.0 2 O00330 1 +Spina bifida occulta 0.2783393092931258 0.2221339977952795 0.8242095725091159 1.0 1.0 20 O43318,Q14999 2 +Thick vermilion border 0.2242905676698929 0.2220387623366138 0.8242837084023624 1.0 1.0 87 Q01105,P21359,Q9BPU6,Q96N67,O00170,Q9UID3,Q9NR45,O96007,Q9Y4X0,A1X283,Q92796,Q14999,P22681 13 +Enlarged cisterna magna 0.2775122443231285 0.2216591929496591 0.8245791991646771 1.0 1.0 19 Q9UID3,P49419 2 +Finger clinodactyly 0.2301986896920881 0.2213819845786088 0.8247950186676887 1.0 1.0 93 P22681,Q03164,Q9BV10,Q6W2J9,Q2TAL8,Q9Y4X0,Q05086,O43318,A1X283,O95352,P57081,Q14999,Q13535 13 +Bulbar palsy 0.2701076298646779 0.2210149756626904 0.825080772410282 1.0 1.0 13 Q9Y263,Q13501 2 +Congenital nonbullous ichthyosiform erythroderma 0.3381503216046805 0.2197231839272502 0.8260867477039764 1.0 1.0 5 P18074 1 +Cutaneous melanoma 0.3592139593695896 0.2183153325701619 0.8271834289090232 1.0 1.0 4 P42771 1 +Cerebral dysmyelination 0.3033399189941821 0.2179518668456391 0.827466614507604 1.0 1.0 7 P18074 1 +Aplasia hypoplasia of the patella 0.316397549665442 0.2178295046441799 0.827561955130395 1.0 1.0 6 Q99741,Q8N806,Q96AY3 3 +Dysmetria 0.1973436752708629 0.2171820435047287 0.828066477927007 1.0 1.0 56 O15020,P21359,P41440,O14802,Q8N0X7,Q9BUK6,Q69YN2,Q96D71,Q13501,P54136,Q06787,P42356 12 +Bruising susceptibility 0.2765103178860298 0.2163719454387197 0.8286978326079988 1.0 1.0 28 O00170,Q6W2J9,Q13126,P49327,P40763,P40818 6 +Abnormal hand morphology 0.2556095225918282 0.2132035865687107 0.8311681709044307 1.0 1.0 121 Q03164,P60866,O00170,O60826,Q92796,Q14999,P62081,P62847,P08708,P62854,O43318,P08243,P21359,Q8N0X7,Q08AM6,P62899,Q9BV10,Q6W2J9,Q2VPK5,P42356,O95630 21 +Abnormality of the female genitalia 0.2761784862218567 0.2122989501789722 0.8318738144008468 1.0 1.0 144 Q16740,P49770,P60866,O00170,P54277,Q9BUR4,P42771,Q06787,Q3SYG4,O75874,Q15392,O60566,P48735,Q8IWV7,P31939,P40818,Q9BW83,P28340,Q15645,O14965,P31751,Q13144,Q08AM6,P20585,P49327,Q06124,P52701,Q13535,Q6W2J9,Q01844,Q07864,Q15058,Q9Y620,Q15042 34 +Coxa vara 0.2700097178830521 0.211887960055383 0.832194443822895 1.0 1.0 15 Q9Y487,Q96AY3,Q9NUQ7 3 +Positive romberg sign 0.2875353152897992 0.2108351437519715 0.8330159141337312 1.0 1.0 8 P41440 1 +Aplasia hypoplasia of the thumb 0.2236064250003892 0.2103646875915698 0.8333830511994376 1.0 1.0 50 P62081,P60866,Q9Y4P8,Q6W2J9,P62847,Q08J23,P08708,P62854,O43318,P42766,Q08AM6,P39019,P62899 13 +Contractures of the joints of the lower limbs 0.2058385446024926 0.209702143099209 0.8339001527748238 1.0 1.0 54 Q96AY3,Q8IWS0,Q6W2J9,P27635,Q08J23,Q06210,Q14738,O43318,P63241,O00330,Q8TD16,O60231,P40763 13 +Weakness of long finger extensor muscles 0.6402985074626926 0.2094260766228443 0.8341156378777836 1.0 1.0 2 Q13501 1 +Tics 0.3130419733148915 0.2090507637075344 0.8344086102765307 1.0 1.0 6 P28482 1 +Decreased number of peripheral myelinated nerve fibers 0.2714176860872406 0.2088666644496987 0.8345523281018601 1.0 1.0 17 Q92734,P50570,O95163,P26358,O60333 5 +Short long bone 0.2582326435087815 0.2083771924679763 0.8349344632378015 1.0 1.0 39 O14802,Q9BV10,O43318,Q9Y4X0,A1X283,Q14999,Q13535 7 +Abnormal t wave 0.3546223531245399 0.2075293976416596 0.8355964363828083 1.0 1.0 4 Q99996 1 +Rigidity 0.1904350837557406 0.2070029239192588 0.8360075750000897 1.0 1.0 57 Q05639,Q9Y3I1,Q9Y3Z3,Q8NC96,Q6PJG6,Q06787,Q15392,O75165,Q08209,Q6Y7W6,Q9Y263,P04350,Q14203,Q04637,Q13057,Q96CU9,P42858,O75792,P52732 19 +Medulloblastoma 0.3117919988087652 0.2058395951175559 0.8369162109840786 1.0 1.0 6 P42771,O96017 2 +Developmental glaucoma 0.2705586904068917 0.2048701240800367 0.8376735976432066 1.0 1.0 31 P62081,P60866,P62847,Q9Y3Z3,P08708,P62854,O75792,P42766,P46783,A1X283,P39019,P62899 12 +Frontal cortical atrophy 0.2697453564353421 0.2040407277178949 0.8383216722158504 1.0 1.0 17 P26196,Q7Z6Z7,Q9BPU6,P42858 4 +Cortical cataract 0.4411794140155123 0.20358754784962 0.8386758247276536 1.0 1.0 3 Q01968 1 +Erythroid hyperplasia 0.3524492234169556 0.2025522525306171 0.8394850132406813 1.0 1.0 4 Q86SX6,P06132,Q9Y606 3 +Aplasia hypoplasia involving bones of the lower limbs 0.229592567020968 0.2025419945737765 0.8394930317269562 1.0 1.0 96 Q03164,P00813,Q9BPU6,Q8N0X7,Q9BV10,Q9NR45,P42858,Q9Y4X0,Q15813,Q08AM6,Q06787,Q13535 12 +Abnormal pleura morphology 0.2721943694429816 0.2006391096048866 0.8409807748163209 1.0 1.0 22 Q92917,Q9UID3,P49327,Q06124,P22681 5 +Abnormality of the tarsal bones 0.2709535921952787 0.200540164449746 0.8410581492377798 1.0 1.0 29 Q9Y263,O15357,O43318,P18074,Q08AM6,Q14999 6 +Progressive gait ataxia 0.2629226297774097 0.2004641041845923 0.8411176288785933 1.0 1.0 13 Q05086 1 +Low apgar score 0.3093079451416032 0.1995537128352082 0.8418296313580533 1.0 1.0 6 P49419 1 +Premature loss of teeth 0.2607137052857685 0.1992157061500038 0.8420940139287494 1.0 1.0 12 Q08AM6,A1X283 2 +Abnormality of primary teeth 0.2668633216613807 0.1992069565443887 0.8421008579447702 1.0 1.0 16 Q6W2J9,Q08AM6,P40763 3 +Abdominal pain 0.2206992791751643 0.1975422083427343 0.8434032546424577 1.0 1.0 88 P40818,P21359,P60866,P11413,Q96BN8,Q70HW3,Q6W2J9,P54277,Q01844,Q15645,P42771,P08397,Q9UER7,P07741,P49327,P52701,P40763,P22681 18 +Narrow face 0.2525403507036292 0.1960104635562968 0.8446019761268406 1.0 1.0 40 Q9BPU6,P26196,Q6W2J9,Q7Z6Z7,P36507,P04350,P42858,Q06787,Q13535 9 +Keratitis 0.2595094554720485 0.1959559361226525 0.8446446551647646 1.0 1.0 12 P18074,P49327 2 +Acute lymphoblastic leukemia 0.2666230732682517 0.1952660403600647 0.8451846811808794 1.0 1.0 17 O60566,Q15645,Q08J23,O43684,P42771,O96017,O43683 7 +Abnormal clavicle morphology 0.2703187375623396 0.194327774827928 0.8459192389817631 1.0 1.0 23 Q6W2J9,Q15813,Q08AM6,A1X283,Q96AY3 5 +Increased blood urea nitrogen 0.6310447761194085 0.1940127254930247 0.846165917722596 1.0 1.0 2 O95163 1 +Inappropriate laughter 0.2808834878573116 0.1934092050326645 0.8466385069671745 1.0 1.0 8 Q05086 1 +Abnormality of exocrine pancreas physiology 0.2690632399563458 0.1929055662317045 0.847032925690979 1.0 1.0 21 P21266,Q9UJW0,P42771,P48506,O00330,Q7Z2Z2,Q8IWV7,P54577,P40763 9 +Abnormality of the small intestine 0.2025359930407061 0.1926450612878762 0.8472369520758485 1.0 1.0 54 P34949,Q7Z2Z2,Q6PGP7,Q92796,Q9H3U1,O60566,Q9Y6B6,O43684,P40763,O00443,O43683,Q7LBC6,Q15645,Q13043,Q9Y5L0,Q9UET6,P50851,Q93008,Q15477 19 +Tongue fasciculations 0.2559663577686448 0.1916048856595902 0.8480517152217286 1.0 1.0 11 P22314,P51114,Q9NX46,Q9BTW9 4 +Hyperinsulinemic hypoglycemia 0.3058845847212594 0.1911006015957259 0.8484467763187631 1.0 1.0 6 P34949 1 +Mild short stature 0.3470728793309351 0.1905939373975028 0.8488437403797642 1.0 1.0 4 P10644,Q13555,Q14739 3 +Abnormal protein glycosylation 0.2608759022457008 0.1905529419002181 0.8488758614358425 1.0 1.0 14 P34949 1 +Abnormal circulating nucleobase concentration 0.2569865928052743 0.1892676098282155 0.8498830800969817 1.0 1.0 12 O96007,P08237 2 +Decreased fertility 0.2671019143363369 0.1886676502621619 0.8503533075467513 1.0 1.0 29 O00170,P57076,Q06124,Q14999,P40818 5 +Delayed myelination 0.2138965055975118 0.1884492934857996 0.8505244612172154 1.0 1.0 83 O60701,Q9Y263,Q9BV10,Q9BY32,P10589,O43776,P49589,Q15813,Q05086,P00374,P08243,Q9UBB6,P49419,O95630,Q16512,Q96CU9,Q08209,Q15042 18 +External ophthalmoplegia 0.2649959770195954 0.1879655382443006 0.8509036661207965 1.0 1.0 18 Q8NCE2,O95352,P50570,Q14331 4 +Red eye 0.2654471625237183 0.1867164204652562 0.8518829808466211 1.0 1.0 19 P18074,P50851,P28070,P49327 4 +Hypointensity of cerebral white matter on mri 0.3039948820556267 0.1865391530633531 0.8520219779395117 1.0 1.0 6 P30566 1 +Abnormal incisor morphology 0.2653755495274914 0.1865230711027654 0.8520345881885982 1.0 1.0 19 P26196,Q7Z6Z7,Q9BPU6,P42858 4 +High myopia 0.2512399367207568 0.1847095459311363 0.8534568584461049 1.0 1.0 10 Q9Y487,P27635,Q7Z2Z2 3 +Miosis 0.6247761194029907 0.1840430444017775 0.8539796870821317 1.0 1.0 2 O60333 1 +Low posterior hairline 0.2572346182496637 0.1838188543033911 0.854155564575757 1.0 1.0 36 P21359,Q9BV10,Q9UID3,Q9NR45,P36507,O60826,Q06124,P28482,Q15042,P22681 10 +Excessive salivation 0.2653343154359103 0.1834118509877586 0.8544748778506202 1.0 1.0 29 P42356,Q05086,Q08AM6,Q92796 4 +Motor polyneuropathy 0.2507207758155786 0.1833961566510449 0.8544871912747689 1.0 1.0 10 P08397 1 +Dysphagia 0.2669565512582363 0.1832229349878808 0.8546230994554487 1.0 1.0 141 Q05639,Q03164,Q14331,Q9BUF5,Q96IJ6,P54136,Q9NW08,Q06787,Q9BPU6,O14802,P00492,P36507,O00429,Q06210,P48735,Q96D71,P67870,Q9BTW9,P29372,Q08209,Q01105,P21359,Q9Y263,Q8N0X7,P04350,P63241,Q05086,Q08AM6,P08397,O75569,O95352,Q92734,Q9UHD2,P42858,Q13501,P42356 36 +Abnormal substantia nigra morphology 0.3434901264326229 0.1829075301543887 0.8548705743654237 1.0 1.0 4 Q15813 1 +Speech apraxia 0.2650058518978287 0.1808384885679732 0.8564943516258832 1.0 1.0 28 P51570,Q9BPU6,Q8N0X7,Q7Z392,P26196,Q7Z6Z7,P42858,O14646 8 +Cleft lip 0.1852697652412418 0.1785581497801601 0.8582846579174186 1.0 1.0 57 P60866,Q6W2J9,P62847,P08708,P62854,O75179,P29372,P62899 8 +Generalized myoclonic seizure 0.2443641000039047 0.175725247676263 0.8605097991687893 1.0 1.0 41 Q05639,Q01105,O60566,P43034,O00429,O00330,Q08209,P49419,P67870,P40763,Q14353 11 +Abnormality of upper limb joint 0.2482319498194303 0.1754135921899258 0.8607546611476191 1.0 1.0 122 Q03164,P18074,Q14999,P22681,Q9H4L7,Q15392,O14802,P38935,Q9NR45,P36507,O43318,O60231,Q96AY3,P21359,Q92917,A1X283,Q06124,P28482,P57081,Q13535,Q9BV10,Q6W2J9,Q15042 23 +Renal hypoplasia aplasia 0.2159959593984605 0.1747846861437424 0.861248821790586 1.0 1.0 88 P21359,P60866,Q15392,Q92917,Q6W2J9,P42695,P62847,P08708,P62854,Q00534,Q2VPK5,Q15477,Q06124,P62899,O75179 15 +Cortical myoclonus 0.618507462686573 0.1744548479230196 0.861508012703448 1.0 1.0 2 O95394 1 +Keratosis pilaris 0.6176119402985133 0.1731162373617989 0.8625600620798286 1.0 1.0 2 Q02750 1 +Abnormal thalamic size 0.6173134328358266 0.1726717623613367 0.8629094407270812 1.0 1.0 2 P11166 1 +Brain imaging abnormality 0.2472199173913768 0.1700705171539418 0.8649546796108019 1.0 1.0 39 O75182,P21359,Q9BV10,O00429,P08397,Q05086,Q13501,Q14353 8 +Germ cell neoplasia 0.2471554564377382 0.1696084692385471 0.865318061570151 1.0 1.0 11 P42771,O96017,P20585 3 +Asthma 0.2613346419974926 0.1689059884791657 0.8658705887545282 1.0 1.0 25 Q00653,P00813,Q14790,Q9UID3,P18074,P50851,O95394 7 +Abnormal blood phosphate concentration 0.2443730930408896 0.1679823655480744 0.8665971521913125 1.0 1.0 10 Q01968,Q15813,O15357 3 +Abnormal bronchoalveolar lavage fluid morphology 0.613731343283588 0.1674054344395618 0.8670510494523767 1.0 1.0 2 P53621 1 +Pulmonic stenosis 0.2561725803023404 0.1673513257328845 0.8670936214198361 1.0 1.0 33 P21359,O14802,Q6W2J9,O43318,O60826,Q06124 6 +Toe clinodactyly 0.2604307205840449 0.1666675044131043 0.8676316755727975 1.0 1.0 26 Q9BPU6,P26196,Q7Z6Z7,P42858,Q93008,Q92796,Q8N806 7 +Shoulder girdle muscle weakness 0.2512217108788645 0.1663368518400681 0.8678918664100235 1.0 1.0 14 Q9Y5L0,Q14331,P46976 3 +Abnormality of the inner ear 0.2430860169642565 0.1650022959599411 0.8689421749134119 1.0 1.0 10 P22681 1 +Olivopontocerebellar hypoplasia 0.4195282173783223 0.1648961595092448 0.8690257152894241 1.0 1.0 3 P30153,Q9UNW1 2 +Abnormality of upper limb metaphysis 0.6119402985074686 0.1648188724481648 0.8690865491287885 1.0 1.0 2 Q9H1A4 1 +Duodenal atresia 0.2559947678963676 0.1648071769387761 0.8690957549123635 1.0 1.0 9 Q7LBC6,O43684,O60566,Q15645 4 +Middle age onset 0.2425613807300345 0.1638015947985106 0.8698873361705566 1.0 1.0 10 Q9H269 1 +Autosomal dominant germline de novo mutation 0.4168954545996157 0.1606080944910306 0.8724020791872502 1.0 1.0 3 P28482 1 +Undetectable light and dark adapted electroretinogram 0.3323799938704118 0.1605188006299302 0.8724724128886192 1.0 1.0 4 Q15555 1 +Triangular face 0.2417652593285996 0.1597211914822296 0.8731007068212588 1.0 1.0 40 O14802,Q15645,Q7Z6Z7,Q14738,Q06124,Q96AY3,O75179,Q14999,P22681 9 +Motor neuron atrophy 0.2568579948129063 0.1596054667136769 0.8731918723767225 1.0 1.0 22 Q92734,P38935,Q99986,Q9UHD2,Q16637,Q14203,Q13501,P22314 8 +Anteriorly placed anus 0.240514144773815 0.1591938407479806 0.8735161563531664 1.0 1.0 10 Q8IWV7 1 +Aplasia hypoplasia of the nails 0.1956186946396433 0.1589874126204772 0.8736787909639421 1.0 1.0 71 Q9H4L7,O14802,Q9BV10,O15357,Q9Y487,P26639,Q7Z6Z7,Q9BUR4,Q08J23,O95630,Q14738,Q99575,P63241,P18074,Q08AM6,O60826,P28482 17 +Multiple joint contractures 0.2538599943117782 0.1575940484255227 0.874776693635857 1.0 1.0 19 P41440,Q92917,P26639,Q9Y3Z3,Q9H0B6,O75792,P18074,P22314 8 +Bradykinesia 0.2556860291279852 0.1557553982529282 0.8762258284899849 1.0 1.0 23 Q9Y3I1,Q6Y7W6,P42858,Q14203,O75165,Q04637,Q13057,Q06787,O75569 9 +Cough 0.2550940489872266 0.1535450498879366 0.8779684668036682 1.0 1.0 27 P41440,Q92734,Q6W2J9,P57076,Q86TI2 5 +Hammertoe 0.2535086554969718 0.1530766811041033 0.878337804914102 1.0 1.0 21 Q8N0X7,Q5TAQ9 2 +Paraparesis 0.2517638033204943 0.15240414945111 0.8788681845210724 1.0 1.0 32 P21359,Q8N0X7,Q6W2J9,Q9UHD2,Q15813,Q13501,Q13057,P42356 8 +Eeg with abnormally slow frequencies 0.2523515695912026 0.1504347406911824 0.880421634019581 1.0 1.0 21 Q05086,Q08209,Q13501,P49419 4 +Narrow palate 0.2128530438376762 0.1498614272137466 0.880873944595423 1.0 1.0 49 Q9BPU6,Q6W2J9,P26639,O43318,P18074,Q08AM6,O60826,Q06124,P28482 9 +Deviation of the hand or of fingers of the hand 0.2407270429036725 0.1498338452434663 0.880895706126877 1.0 1.0 121 P22681,Q03164,Q9BPU6,Q9BV10,Q9Y4X0,Q05086,Q2VPK5,A1X283,P42356,O95352,P57081,Q15042,Q14999,Q13535 14 +Abnormality of the peritoneum 0.251053315386445 0.1492042979592538 0.8813924286762249 1.0 1.0 20 P42771,Q01844,O95163,Q9Y5K6 4 +Abnormality of thyroid physiology 0.2031347149102962 0.1487339425089744 0.881763576869266 1.0 1.0 81 P34949,P00813,O00170,Q9Y3Z3,Q9BUK6,Q06787,O14802,O60566,P27635,O00429,Q8IWV7,P40763,Q9Y263,Q15645,P50851,P57081,Q6W2J9,Q93008,Q15477 19 +Abnormal prostate morphology 0.2602318311843118 0.1462723236650124 0.8837064133590966 1.0 1.0 8 P42771,Q8IWS0 2 +Limb joint contracture 0.2260666009908351 0.1458182509230415 0.8840648677521041 1.0 1.0 106 Q9NPF4,P18074,Q9H4L7,Q15392,O14802,P38935,P27635,Q06210,O43318,O60231,Q8IWS0,Q96AY3,P40763,Q92917,Q08J23,O00330,P63241,A1X283,P28482,P57081,Q13535,Q6W2J9,Q14738,Q8TD16,Q15042 25 +Hip contracture 0.2383263648437034 0.145721733229156 0.884141063872621 1.0 1.0 12 O43318,Q8TD16,Q96AY3 3 +Abnormality of the nasal tip 0.2185100220893167 0.1453027578929051 0.884471837351817 1.0 1.0 98 Q03164,Q7LBC6,Q96N67,Q9Y487,Q6W2J9,Q9BSJ2,O43318,A1X283,Q92796,Q06787,Q15042,Q14999 12 +Aplasia hypoplasia of fingers 0.2166305801581108 0.1452901163856106 0.8844818179073122 1.0 1.0 96 Q03164,P60866,O60826,Q92796,Q14999,P62081,P62847,P27635,P08708,P62854,O43318,P42766,P39019,Q8IWS0,Q9Y4P8,Q08J23,Q08AM6,Q9UET6,P28482,P62899,Q6W2J9,Q93008,P46109,O95630 24 +Macrotia 0.2099459050085521 0.1450998991963158 0.8846319978768156 1.0 1.0 89 Q01105,Q9BPU6,O00170,P26196,O43776,Q7Z6Z7,P27635,Q2TAL8,P36507,P42858,Q2VPK5,P08243,P48449,Q9BTW9,Q06787,P57081,Q15042,P22681 18 +Abnormal size of the clitoris 0.250453150681344 0.1448175391184017 0.8848549339933411 1.0 1.0 22 Q08AM6,P31939,Q13535 3 +Albuminuria 0.2847855463936948 0.1444463888995678 0.885147987826308 1.0 1.0 6 P40763 1 +Hypochromic anemia 0.239228347469111 0.1437309961214807 0.8857128939602128 1.0 1.0 13 Q9UER7 1 +Adrenal hypoplasia 0.2455568662889204 0.1426101520768418 0.8865980792421266 1.0 1.0 9 Q07864 1 +Abnormality of the incisor 0.2490470756153961 0.1418574338132354 0.8871926171058704 1.0 1.0 30 Q6W2J9,P42858,Q9BPU6,Q9BSJ2 4 +Neoplasm of the liver 0.2354402658564552 0.1412390681081182 0.8876810835201472 1.0 1.0 40 P60866,Q14790,Q15645,P54277,P42771,Q9Y5L0,P08397,P49327,P52701,Q15477 10 +Gonadal neoplasm 0.2495480964868702 0.140974641203345 0.8878899756373215 1.0 1.0 28 O75874,P54277,Q01844,P48735,P42771,P20585,P52701 7 +Myopathy 0.2125939288866694 0.1407557792765704 0.8880628781977506 1.0 1.0 93 P11310,Q8NCE2,Q9Y6B6,O00429,Q06210,Q13126,Q9BUK6,Q9Y5L0,Q15813,P40818 10 +Acute phase response 0.2486158437680949 0.1396633315090232 0.8889259995989862 1.0 1.0 29 P21359,Q969U7,P28070,Q96BN8 4 +Choroid plexus carcinoma 0.4030061635898421 0.1394779226256609 0.8890725005957878 1.0 1.0 3 P42771 1 +Hyperlordosis 0.2058536301757874 0.1380394496599611 0.8902092396523735 1.0 1.0 50 P21359,P50570,Q14331,Q8NCE2,Q7Z392,Q6W2J9,Q06210,Q99575,P28482,Q15042,Q14999 11 +Abnormality of the antihelix 0.2322381169756473 0.1376157564481861 0.8905441021698977 1.0 1.0 11 P27635,Q15042 2 +Flared nostrils 0.2997884590673314 0.1368498220575152 0.8911495017592959 1.0 1.0 5 Q93008,O75179 2 +Abnormality of the cervical spine 0.2242834818966602 0.1362983139740715 0.8915854567007298 1.0 1.0 107 P60866,Q00535,Q9C0B1,Q15555,P18074,O60826,Q3SYG4,Q14999,P22681,P62081,O14802,O60566,P04075,Q9NR45,P62847,P36507,P08708,P62854,Q9Y4X0,P42766,Q9BW83,P21359,Q92917,O15357,P07437,Q06124,P28482,P62899,P43034,Q99575,Q07864 31 +Avascular necrosis of the capital femoral epiphysis 0.3997422653731063 0.1348740730362013 0.8927114389363706 1.0 1.0 3 Q9NUQ7 1 +Tetraplegia 0.233606462640266 0.1327370545806484 0.8944013368289547 1.0 1.0 13 Q9BTW9 1 +Decreased head circumference 0.191070813577528 0.1327078859010821 0.8944244059860869 1.0 1.0 478 Q16740,Q05639,Q03164,Q00535,Q2M389,O43772,Q7Z392,Q7Z6Z7,Q9Y3Z3,Q96KP1,P54136,Q9Y6D5,O60701,Q15392,Q9BPU6,O60566,P26196,P26639,P62847,P27635,Q8IWS0,Q01105,Q9Y263,Q08J23,O00330,Q05086,Q08AM6,Q96CU9,Q13535,P53618,P51570,P48444,P43034,P26640,Q2VPK5,P42356,Q14204,Q15042,Q9Y285,P49770,Q9P2J5,Q9UID3,Q9NPF4,Q9C0B1,Q14232,O43505,O15111,Q9Y487,P08708,P47897,P42766,P41252,P61960,P67870,Q9BTW9,P39019,Q92974,Q08209,Q8N806,P21359,Q8N0X7,Q96I59,Q13144,Q9BSJ2,Q9UEY8,Q01433,P57081,P62899,Q9BV10,Q6W2J9,O60610,O15347,O00203,Q07864,P42858,Q00534,P46109,P62266,P46783,Q9UBB6,Q15021,Q15813,P18074,Q96F86,Q9NR45,O00429,P62854,P08243,Q92917,Q2TAL8,O96007,P00374,P48449,Q13057,Q96C86,Q69YN2,O75179,O95630,O75182,P60866,P42695,Q15555,Q96IJ6,P62081,Q8IWV7,Q9NSD9,Q15645,O43776,P04350,P07437,P63241,P28482,Q9BY32,Q9NUQ7,Q14746,Q15058,P49589,P30566 118 +Short thumb 0.2226885723545034 0.1320958946315905 0.8949084430676706 1.0 1.0 44 P60866,Q6W2J9,P62847,P08708,P62854,O43318,P62899 7 +Abnormal blood ion concentration 0.1946230419107319 0.1308312343353414 0.8959088139294977 1.0 1.0 77 Q00653,P21359,Q4J6C6,Q99996,Q9BV10,O00170,O15357,Q9Y487,Q9NSD9,Q9UHD2,O95163,Q15813,P08397,Q15477,Q8IWV7,P40818 16 +Atrophy degeneration involving the corticospinal tracts 0.2325521048516644 0.1307780963262051 0.89595085076174 1.0 1.0 13 Q9UHD2,Q13501,Q15056 3 +Abscess 0.2517637753108487 0.1299944973031611 0.8965707802657243 1.0 1.0 8 P42771 1 +Abnormal sternum morphology 0.232847684710933 0.1294784198191062 0.8969790996934617 1.0 1.0 119 Q03164,Q15555,Q9BUK6,Q06787,Q14999,P22681,Q9Y487,P36507,O43318,Q96AY3,Q9BTW9,Q9NSD9,P21359,Q9Y263,O15357,O43776,Q08AM6,A1X283,Q06124,O95352,Q6W2J9,P42356 22 +Pointed chin 0.2412308933009485 0.1291886980446684 0.8972083389217202 1.0 1.0 33 O60701,Q7LBC6,O14802,O00429,Q15056,O43318,O14646,P46109,P28482,P52732,Q14999 11 +Axonal regeneration 0.3929531203344231 0.1257333704271389 0.8999429856956771 1.0 1.0 3 Q8TB36,P54577 2 +Irregular femoral epiphysis 0.3122595194109692 0.1255467741765931 0.9000906975028704 1.0 1.0 4 Q99741,Q9NUQ7 2 +Proximal muscle weakness in lower limbs 0.2368675529617452 0.1246972377274697 0.900763244307032 1.0 1.0 18 P50570,Q8NCE2,P08397,Q00796,Q14204 5 +Abnormal shape of the occiput 0.2397161165023653 0.123999186602062 0.9013159190908036 1.0 1.0 32 Q9Y617,O15357,Q05086,P62266,O60826,A1X283,P30566,Q01968,A5YKK6,P52732,O15111 11 +Spastic hyperactive bladder 0.2723918270448243 0.1214365827319016 0.903345242449366 1.0 1.0 6 Q6Y7W6,O75165,Q04637 3 +Mitral valve prolapse 0.2403306720640542 0.121286755007152 0.9034639105411456 1.0 1.0 26 P21359,Q6W2J9,O43318,A1X283,Q06124,Q06787 6 +Childhood onset 0.2323849114784664 0.1203325815699742 0.9042196952635466 1.0 1.0 37 Q00653,Q8N0X7,Q14331,Q9NUQ7,O60610,Q14204,Q8TEQ6,Q15813,Q01968,Q9H269,P40763 11 +Immunodeficiency 0.1837466352955326 0.1196726623705614 0.904742456962256 1.0 1.0 69 Q00653,P11586,P00491,P00813,O60566,Q9UHD2,Q9BUR4,Q07864,P17812,P48506,Q15813,Q13432,O14646,P50851,Q15477,P28482,O95394,P40818 18 +Aortic regurgitation 0.2390133158222237 0.1188031359581652 0.9054313241474714 1.0 1.0 26 O60566,Q15645,O43684,P46109,Q6PGP7,P49327,Q15477,P28482,Q9Y6D5,O43683 10 +Bell shaped thorax 0.2701733413030425 0.1176582673902189 0.9063384348223368 1.0 1.0 6 O15357,Q8WVQ1,Q96HY6,O75369,Q96EX3 5 +Abnormality of urine calcium concentration 0.2249642893431458 0.1176201271198936 0.9063686565113178 1.0 1.0 13 Q01968,Q9Y4X0,Q9UNF1,Q15056 4 +Male reproductive system neoplasm 0.2266737865252084 0.1174144179696264 0.906531659212146 1.0 1.0 14 Q01844 1 +Abnormal morphology of the radius 0.2264875901839474 0.1171105146872473 0.906772477558876 1.0 1.0 14 Q32P28,Q9BV10,Q13535 3 +Abnormality of skull ossification 0.2242984698880791 0.1165431128097315 0.9072221197849032 1.0 1.0 13 Q08AM6 1 +Death in adulthood 0.2260848548810096 0.1164565129556963 0.907290749161539 1.0 1.0 14 P54277,P43246,Q15056,P52701,Q9UN37 5 +Urinary incontinence 0.2141135135729775 0.116311718080523 0.9074054989611002 1.0 1.0 45 P38935,Q8NCE2,P26358,P08397,Q92796,Q9BTW9,Q06787 7 +Lumbar hyperlordosis 0.2275636874922278 0.1160797314831417 0.907589352144354 1.0 1.0 15 Q06210 1 +Irritability 0.1921592968930418 0.1158228631918777 0.9077929302537392 1.0 1.0 79 P60866,Q9BY32,P54277,O43772,Q9Y5K6,P42858,P49589,P26358,P06737,Q13501,P49327,P49419,P52701,Q06787 14 +Abnormal uterus morphology 0.2352323806485168 0.1148862283732167 0.9085353009784048 1.0 1.0 32 P28340,P60866,O14965,Q07864,P20585,Q9Y620,P52701 7 +Spastic diplegia 0.2363253542500877 0.1143227313384753 0.908981963628605 1.0 1.0 25 Q6IA86,Q6W2J9,Q7Z6Z7,O00330,Q9UEY8,Q15042 6 +Bowing of the arm 0.2859276964445696 0.1138820892440214 0.909331263899759 1.0 1.0 5 O75369,Q96L58,Q32P28,P16435 4 +Proximal amyotrophy 0.2219781299714089 0.1128857109472844 0.9101211649253852 1.0 1.0 13 Q06210 1 +Diffuse mesangial sclerosis 0.2297811156322343 0.112600226092717 0.9103475057947312 1.0 1.0 18 Q14C86,P00813,Q9Y5K6 3 +Abnormality of the cerebral subcortex 0.1958377202061431 0.1125749868861595 0.9103675165374248 1.0 1.0 391 Q05639,Q03164,Q00535,Q2M389,Q7Z392,Q7Z6Z7,Q9Y3Z3,Q96KP1,P54136,Q9NW08,Q9Y6D5,Q15392,Q9BPU6,O60566,P26196,P26639,Q01105,Q9Y263,Q05086,Q08AM6,Q9H269,Q96CU9,O95352,Q13535,P49419,Q15042,Q9UID3,Q9P0J0,Q9BUK6,Q16512,P26358,P67870,Q9BTW9,Q08209,P21359,Q9BSJ2,Q01433,A1X283,P57081,Q9BV10,Q6W2J9,P42858,Q00534,Q9UBB6,Q969U7,Q15813,P18074,Q96F86,Q96N67,Q9NR45,O00429,P08243,O60231,P29372,Q7LBC6,Q92917,O96007,P48449,Q13057,Q96C86,Q99986,Q69YN2,Q13501,O95630,O75182,P42695,Q15555,O14802,P36507,Q96D71,Q15645,P10589,O43776,P07437,Q9NUQ7,Q14746,Q15058,Q14738,P49589,P30566 80 +Inappropriate behavior 0.2267197508333265 0.1121935748922867 0.9106699234997832 1.0 1.0 16 Q9Y617,Q05086,Q13501,P30566 4 +Punctate cataract 0.3816064496864682 0.1117497619122312 0.9110218221010772 1.0 1.0 3 Q15436,P08670 2 +Premature skin wrinkling 0.2286156843982959 0.1107510967918021 0.9118137257943078 1.0 1.0 18 Q9Y487,O14802,Q06124 3 +Hypertriglyceridemia 0.2329014979267378 0.1100464597408546 0.9123725290930872 1.0 1.0 23 P28340,P31751,O14802,P28070 4 +Chordee 0.2653915122534326 0.1098613792303813 0.9125193119947776 1.0 1.0 6 P53701,O60341,P48651,P16435,P49589 5 +Renal cortical microcysts 0.3798783382224718 0.1097595580065381 0.9126000652315764 1.0 1.0 3 Q8TD19 1 +Simple febrile seizure 0.3798148701104757 0.1096871567657758 0.912657486368602 1.0 1.0 3 P11166,Q96CW1 2 +Ectopia lentis 0.2156530401388058 0.1095546731960553 0.9127625597429856 1.0 1.0 11 Q6W2J9 1 +Thin vermilion border 0.242650493153243 0.1091325419986997 0.913097364245764 1.0 1.0 140 Q03164,Q9UID3,P42695,Q7Z6Z7,Q96KP1,Q15813,Q92796,Q06787,Q9BPU6,O14802,P26196,Q9Y4X0,P29372,P31939,P21359,Q7LBC6,Q2TAL8,Q9BSJ2,P63241,Q08AM6,A1X283,P28482,Q9BV10,Q96C86,Q15058,P42858,Q14738,Q00534,P30566,O75179,Q15042 31 +Limb girdle muscle weakness 0.2329215400358814 0.1080666378044297 0.9139428323062652 1.0 1.0 26 Q14331,Q06210,Q13126,Q9Y5L0,P46976 5 +Generalized hypotonia 0.2076267341435876 0.1079534835286802 0.9140325912541178 1.0 1.0 371 P11310,Q03164,Q05639,Q70HW3,O43772,Q2M389,Q7Z460,Q7Z6Z7,Q7Z392,O95394,Q9Y6D5,O60701,O60566,P26639,P27635,Q9Y4X0,Q8IWS0,Q01105,Q99707,Q08J23,Q05086,O14646,P14854,Q96CU9,P50570,P26640,Q93008,Q2VPK5,P49419,Q9Y285,P49770,P34949,O75880,Q9P2J5,Q9UID3,Q9P0J0,Q9NPF4,Q9BUK6,Q14232,P27708,Q16512,P22681,O15020,Q9Y487,Q06210,P61960,P67870,Q08209,Q8N0X7,Q13144,Q9BV10,Q6W2J9,Q9UBB6,Q8NCE2,Q15813,P18074,O60826,Q96F86,Q93100,Q9NR45,O00429,O60231,P31939,Q4J6C6,Q7LBC6,P00374,Q96C86,Q99986,Q69YN2,O95630,Q15555,Q96IJ6,O14802,P00492,Q96D71,Q8IWV7,Q9NSD9,O15357,O43776,O95163,P07437,P28482,Q9BWD1,Q9H2U2,Q9NUQ7,Q15058,Q14738,P30566 88 +Abnormal eyelid morphology 0.1792691583958669 0.1079534727436934 0.914032599809296 1.0 1.0 371 Q05639,Q03164,Q14331,Q7Z6Z7,Q9Y3Z3,Q96KP1,O95394,Q3SYG4,O60701,Q15392,Q9BPU6,O60566,P26196,P26639,P62847,P27635,Q9Y4X0,Q8IWS0,Q9BW83,Q08J23,O00330,Q05086,Q08AM6,O14646,O75569,Q13535,P53618,P43034,P26640,Q93008,Q2VPK5,Q9UID3,Q9BUR4,Q92796,P22681,Q9Y487,P08708,Q9BTW9,Q08209,P21359,Q8N0X7,Q9BSJ2,Q01433,A1X283,P57081,P62899,Q9BV10,Q6W2J9,P42858,Q00534,Q9UBB6,P11172,O00170,P18074,O60826,Q96N67,Q9NR45,P62854,O43318,O60231,P29372,Q4J6C6,Q92917,Q2TAL8,P48449,P49327,Q06124,O75179,P60866,P42695,Q15555,P62081,O14802,P36507,Q15645,P10589,O43776,P07437,P63241,P28482,Q15058,Q14738 82 +Accessory oral frenulum 0.3772359201627155 0.1067865288303384 0.9149583347970274 1.0 1.0 3 O15111 1 +Absent toe 0.2310111629206591 0.1054227239539562 0.9160403854262 1.0 1.0 25 Q08AM6,Q7Z6Z7,Q9BPU6,P42858 4 +Abnormality of the outer ear 0.1942792809824712 0.1054126312712855 0.9160483936010582 1.0 1.0 360 Q05639,Q03164,Q7Z6Z7,Q9Y3Z3,Q96KP1,Q3SYG4,Q14999,O60701,Q15392,Q9BPU6,O60566,P26196,P26639,P62847,P27635,Q9Y4X0,Q8IWS0,Q9BW83,Q01105,Q9Y263,Q08J23,Q08AM6,Q13535,P43034,P26640,Q93008,Q2VPK5,Q8TD16,Q15042,Q9UID3,Q9NPF4,P22314,Q16512,O43505,P22681,O15111,Q9Y487,P08708,P47897,P42766,P39019,Q9BTW9,Q8N806,P21359,Q8N0X7,Q9BSJ2,Q01433,Q9UET6,A1X283,P57081,P62899,Q9BV10,Q6W2J9,O60568,O15347,O00203,Q07864,P42858,O15160,P46109,P62266,P11172,O00170,Q15813,P18074,O60826,Q06787,Q96N67,Q9NR45,P62854,O43318,P08243,O60231,P31939,Q4J6C6,Q7LBC6,Q92917,Q2TAL8,P48449,Q06124,Q96C86,O95630,P60866,Q15555,P62081,O14802,P36507,Q15645,P10589,O43776,P07437,P63241,P28482,Q15058,Q14738,P30566 96 +Abnormal hair morphology 0.1822072601965665 0.1042579261896825 0.916964665931372 1.0 1.0 355 O75182,Q03164,P00813,P60866,Q00535,O00170,Q14331,Q9UID3,Q9P0J0,Q7Z6Z7,Q9BUR4,Q15555,Q9BUK6,P42771,P18074,O60826,Q06787,Q3SYG4,Q14999,P22681,Q00653,O60701,P62081,Q9BPU6,Q96N67,O14802,Q9NR45,Q9Y487,P26639,P62847,P36507,P08708,P62854,Q13126,P26196,Q9Y4X0,O43318,P27635,P11802,Q8IWV7,Q9BTW9,Q8IWS0,P29372,P40763,P40818,Q9BW83,P21359,Q4J6C6,Q9Y263,Q08J23,Q9BSJ2,P07437,P63241,Q05086,Q08AM6,O14646,P48449,P49327,Q06124,P28482,Q96CU9,P62899,Q13535,P53618,Q9BV10,Q6W2J9,P26640,Q99575,P42858,P49589,Q69YN2,Q2VPK5,Q15477,O75179,O95630,Q15042 76 +Elevated hepatic transaminase 0.208116986432731 0.1042010987800457 0.917009762020399 1.0 1.0 101 P28340,P11310,O75880,Q9BV10,O43772,Q9Y6B6,Q9UER7,P28070 8 +Abnormality of skin pigmentation 0.2364215079647115 0.104108270110321 0.9170834279259517 1.0 1.0 135 O00170,Q7Z392,Q7Z6Z7,Q9BUR4,Q15555,P42771,P18074,Q96IJ6,P22681,O60333,Q9H4L7,Q9BPU6,O60566,P26196,P26639,P36507,P11802,O43318,Q8IWV7,Q96AY3,P40818,P21359,Q15645,Q08J23,Q9Y5L0,P07437,Q05086,P50851,A1X283,P49327,Q06124,P52701,P28482,P53618,Q96C86,P42858,Q15477 37 +Bilateral ptosis 0.2178028426673564 0.1039983330606178 0.9171706714232372 1.0 1.0 14 P40763,O00429 2 +Short palm 0.2300956215583977 0.1039791755559583 0.917185874477468 1.0 1.0 25 O15357,Q15555,Q15813,O43318,A1X283 5 +Metaphyseal irregularity 0.2156384287091595 0.1036379656254075 0.9174566576645132 1.0 1.0 13 Q9NR45 1 +Absent epiphyses 0.2484304932735519 0.1035165508857815 0.9175530143526542 1.0 1.0 7 Q99741,Q7LGA3,O60568,Q8WVQ1,Q14807,O00443 6 +Severe global developmental delay 0.179560315808353 0.1032030935374415 0.9178017847364892 1.0 1.0 70 O60701,Q9BPU6,O60566,Q9BV10,Q9UID3,Q7Z6Z7,Q96KP1,P42858,P18074,P30566,O95630,Q14353 12 +Redundant skin 0.2296609164565882 0.102628981439451 0.9182574404218328 1.0 1.0 29 Q9Y487,Q08AM6,A1X283 3 +Increased head circumference 0.2267747504736141 0.1023350447652268 0.918490739613124 1.0 1.0 124 P49770,P11310,Q8NCE2,Q7Z6Z7,Q14232,O60826,Q92796,Q16512,Q06787,Q15392,Q9BPU6,O14802,P26196,P36507,Q8IWS0,P21359,O15357,Q13144,O96007,Q05086,O14646,P50570,Q99575,Q07864,P42858,Q93008,Q14738,Q8TD16,O75179 29 +Hyperphosphaturia 0.2954002389486196 0.1016626765917119 0.919024428367827 1.0 1.0 4 Q01968,O14745,Q08426 3 +Abnormal pupil morphology 0.2120278660411449 0.1015151886202701 0.9191415010683424 1.0 1.0 12 O95163,Q96IJ6 2 +Embryonal renal neoplasm 0.2117801705385527 0.1011882473422144 0.9194010260936354 1.0 1.0 12 Q9UPY3,O43684,O60566,Q15645 4 +Contractures involving the joints of the feet 0.2244080374895146 0.1009578232681002 0.9195839412058676 1.0 1.0 20 Q6W2J9,Q08J23,Q14738,P63241,Q8IWS0 5 +Gastrostomy tube feeding in infancy 0.227508935905111 0.1009534438282293 0.9195874177316624 1.0 1.0 32 Q05639,O60701,Q01105,Q9BV10,O00429,P67870,Q08209 7 +Reduced consciousness confusion 0.2267269372478687 0.100459126374553 0.919979831058276 1.0 1.0 125 P49770,P11310,P60866,O43772,P18074,Q00653,P62081,P62847,P08708,P62854,P26358,P40763,P40818,P31751,Q13144,Q9Y5L0,P08397,P49327,Q96CU9,P62899,P42858 21 +Abnormality of facial skeleton 0.211216664779744 0.1003330923828794 0.9200798861151344 1.0 1.0 338 P60866,P00813,Q00535,O00170,Q7Z6Z7,Q9BUR4,Q15555,Q9BUK6,Q15813,P18074,O60826,Q92796,Q06787,O95394,Q14999,P22681,Q00653,P62081,Q15392,Q9BPU6,O14802,O60566,Q9Y487,P26196,P62847,P57076,P08708,Q06210,P62854,P36507,Q9Y4X0,O43318,P26639,P08243,P67870,Q9BTW9,Q08209,P28070,P28340,P21359,Q4J6C6,Q9Y263,Q92917,O15357,Q15645,O43776,Q9BSJ2,P07437,Q13432,Q05086,Q08AM6,P63241,A1X283,P50851,Q06124,Q13057,P28482,P57081,O95352,Q13535,P62899,Q9BV10,Q07864,P42858,Q15058,Q2VPK5,P42356,O95630,Q15042 69 +Skin plaque 0.2583684814383424 0.0992582218517777 0.920933248685384 1.0 1.0 6 Q92990 1 +Gait disturbance 0.1799039092787266 0.0987172595455097 0.9213627646672436 1.0 1.0 331 Q05639,Q03164,Q7Z392,Q7Z460,Q7Z6Z7,Q9Y3Z3,P54136,O60333,Q9BPU6,P38935,P26196,P26639,P27635,Q5TAQ9,Q99707,Q8TEQ6,O00330,Q05086,Q08AM6,P13639,Q9H269,Q96CU9,O75569,P46976,P53618,P48444,P50570,P26640,Q93008,Q8TD16,Q14204,P49770,Q9Y3I1,Q9UID3,Q9H0B6,Q9BUK6,Q14232,Q16512,O15020,Q06210,Q9BTW9,Q08209,P40818,Q8N0X7,Q13144,Q01433,Q00796,Q92734,P42858,P41440,Q8NCE2,P18074,Q06787,Q96N67,O00429,O60231,Q4J6C6,Q2TAL8,P49327,Q13057,Q96C86,Q69YN2,Q13501,P60866,P54277,Q96IJ6,Q96D71,Q96AY3,O43776,O95163,P04350,P52701,Q9NUQ7,Q9NUW8,Q14738,P49589,P30566 77 +Minimal change glomerulonephritis 0.2133013780707034 0.0979957445458519 0.9219356724651856 1.0 1.0 14 Q12769,Q9BW27,Q8N1F7,Q92621,Q9NQW6,Q9P2R3,Q9Y5K6,Q8WUM0,P52565,O43707,Q8NFH4,Q14C86,Q27J81 13 +Gliosis 0.2035361039406117 0.0978762276751743 0.9220305769019674 1.0 1.0 46 P49770,Q9Y3I1,Q7LBC6,Q6Y7W6,Q9NR50,Q92734,Q96I59,Q99986,Q9UHD2,Q13144,Q04637,P42858,Q14232,O96007,O75165,Q6PJG6,Q13501,Q9BTW9 18 +Abnormality of skin physiology 0.2053055740038062 0.0973496293129644 0.922448744636551 1.0 1.0 101 P00813,O00170,Q9Y3Z3,P18074,O95394,P22681,Q00653,Q9H4L7,O14802,P26639,P40763,P28070,P40818,Q15126,Q14790,Q9Y5L0,P50851,A1X283,P48449,P49327,Q96BN8,Q07864,P53602 23 +Abnormality of the curvature of the vertebral column 0.1774502844380497 0.0973325726614771 0.92246228955218 1.0 1.0 325 Q13614,Q05639,O00170,Q14331,Q8NCE2,Q7Z392,Q7Z6Z7,Q9BUR4,Q9Y3Z3,Q9BUK6,Q15813,P18074,O60826,Q06787,O95394,Q9Y6D5,Q14999,P22681,O75874,Q9BPU6,O14802,P38935,Q9Y487,P26196,P36507,P26639,O00429,Q06210,P48735,P27635,O43318,P67870,Q9BTW9,Q96AY3,Q8IWS0,Q08209,P40763,P40818,P28340,Q01105,P21359,Q9NSD9,Q9Y263,Q8N0X7,O15357,O43776,Q2TAL8,Q08J23,O95163,P04350,Q05086,A1X283,Q00796,P48449,Q06124,P28482,Q96CU9,O95352,Q13535,P53618,Q9BV10,P50570,Q9NUQ7,P43034,Q6W2J9,Q07864,P42858,Q14738,Q99575,Q93008,Q8TD16,Q32P28,O75179,Q14204,Q15042 75 +Abnormality of the forehead 0.2017513072429407 0.0968711330573671 0.9228287334486368 1.0 1.0 323 Q05639,Q03164,P60866,Q9P2J5,O00170,P42695,Q7Z6Z7,Q96KP1,Q15813,P18074,O60826,Q16512,Q06787,Q14999,P22681,P62081,Q15392,Q9BPU6,Q96N67,O14802,O60566,Q9NR45,Q9Y487,P26196,P62847,P36507,P08708,P62854,P27635,Q9Y4X0,O43318,P08243,Q9BTW9,P29372,P31939,Q08209,P40763,Q9NSD9,P21359,Q4J6C6,Q92917,O15357,Q15645,O43776,Q08J23,Q9BSJ2,O96007,P63241,O00330,Q08AM6,Q01433,A1X283,O14646,Q06124,Q13057,P28482,P57081,P62899,Q13535,P43034,P26640,Q14204,Q07864,P42858,Q15058,Q00534,Q2VPK5,Q14738,P49589,Q93008,Q15477,O75179,P30566,O95630,Q15042 75 +Coarse hair 0.2184779637715476 0.0962692577429025 0.923306726423818 1.0 1.0 18 Q9Y487,P22681 2 +Peritonitis 0.213365298172003 0.0957810966439136 0.9236944310172246 1.0 1.0 15 Q12769,Q9BW27,Q8N1F7,Q92621,Q9NQW6,Q9P2R3,Q9Y5K6,Q8WUM0,P52565,O43707,Q8NFH4,P38398,Q14C86,Q27J81 14 +Abnormality of hair texture 0.1729457463161798 0.095772461392046 0.9237012894223866 1.0 1.0 55 O75182,Q9BPU6,Q9Y487,P26639,P36507,Q08J23,P49589,P18074,Q15477,Q06124,P22681 11 +Retinal hemorrhage 0.2428553774315802 0.095662425891822 0.9237886837846324 1.0 1.0 7 Q9Y487 1 +Abnormality of the gastric mucosa 0.2132215911204451 0.0956028437409088 0.92383600656976 1.0 1.0 15 Q15477,P49327 2 +Demyelinating peripheral neuropathy 0.2148490761354688 0.0955036407914725 0.9239147985471544 1.0 1.0 16 O75792,P41440,P18074,Q9Y3Z3 4 +Aplasia hypoplasia involving the skeleton 0.1788799797718746 0.0952558935197095 0.9241115751630564 1.0 1.0 316 Q03164,P00813,P60866,Q00535,Q7Z6Z7,Q15555,Q9BUK6,Q15813,P18074,O60826,Q92796,Q06787,Q14999,P22681,P62081,Q15392,Q9BPU6,O14802,O75874,O60566,Q9NR45,P26196,P26639,P62847,P27635,P08708,P62854,P48735,Q9Y4X0,O43318,P08243,Q9BTW9,Q96AY3,Q8IWS0,Q08209,P28340,P21359,Q9Y263,Q8N0X7,Q92917,O15357,Q15645,Q08J23,P07437,P63241,Q08AM6,A1X283,Q06124,Q13057,P28482,P57081,P62899,Q13535,Q9BV10,P48444,Q6W2J9,P26640,Q07864,P42858,Q15058,Q99575,Q2VPK5,Q93008,Q8TD16,Q32P28,P42356,O95630,Q15042 68 +Abnormal facial shape 0.1721407156885174 0.0943330543073489 0.924844593438706 1.0 1.0 312 O75182,Q05639,Q03164,O00170,Q2M389,Q7Z6Z7,Q15555,Q96KP1,Q9BUK6,P18074,Q16512,Q06787,Q96F86,O95394,Q14999,P22681,Q9BPU6,O14802,O60566,Q9NR45,Q9Y487,P26196,P36507,P26639,P08708,Q06210,Q9Y4X0,O43318,P67870,Q96AY3,Q08209,P40763,P40818,Q01105,P21359,Q9Y263,Q15645,P10589,P04350,O96007,P07437,Q05086,A1X283,Q06124,P28482,P57081,O95352,Q13535,Q9BV10,Q96C86,Q9NUQ7,Q6W2J9,Q07864,P42858,Q14738,Q9UBB6,Q15477,O75179,P30566 59 +Abnormal blood chloride concentration 0.365051336521918 0.0941525112285074 0.9249880076761692 1.0 1.0 3 Q13618 1 +Abnormal corpus callosum morphology 0.2212319742770291 0.0938739749267474 0.9252092675250294 1.0 1.0 310 O75182,Q05639,Q03164,Q00535,Q9UID3,Q2M389,P42695,Q7Z6Z7,Q9Y3Z3,Q15555,Q96KP1,Q15813,P18074,P54136,Q9NW08,Q96F86,Q9Y6D5,Q15392,Q9BPU6,Q96N67,O14802,O60566,Q9NR45,P26196,P26639,P36507,O00429,Q96D71,P08243,P67870,Q9BTW9,O60231,P29372,Q08209,Q01105,P21359,Q7LBC6,Q9Y263,Q92917,Q15645,P10589,O43776,Q08J23,Q9BSJ2,O96007,P07437,Q05086,Q08AM6,Q01433,A1X283,P48449,O00330,Q13057,P57081,O95352,Q9BV10,Q96C86,Q9NUQ7,Q6W2J9,P43034,P26640,Q14746,Q15058,P42858,Q14738,Q00534,Q69YN2,P49589,Q93008,Q9UBB6,Q8TD16,P49419,O95630,Q15042 74 +Hyperkalemia 0.2712325272541863 0.0934538964781263 0.925542974620952 1.0 1.0 5 Q13618,P04075 2 +Retinal detachment 0.2129735906525828 0.0932063012893587 0.9257396684790706 1.0 1.0 16 Q9BV10,Q14331,Q6W2J9,P49327,O43505 5 +Abnormal palate morphology 0.1991051620887269 0.0929491165845008 0.9259439852191896 1.0 1.0 306 Q03164,P60866,Q9UID3,Q9NPF4,Q7Z6Z7,Q9C0B1,Q15555,Q9BUK6,Q15813,P18074,Q9BUF5,O60826,Q92796,P22314,O95394,O43505,P22681,O15111,P62081,Q15392,Q9BPU6,O60566,O14802,P26196,P26639,P62847,Q9Y487,P08708,Q06210,P62854,P36507,Q9Y4X0,O43318,P42766,P39019,P29372,Q92974,Q08209,P40763,Q9NSD9,Q01105,P21359,Q9Y263,O15357,Q15645,Q2TAL8,Q08J23,P07437,O00330,P63241,Q08AM6,A1X283,Q06124,P28482,P57081,O95352,Q13535,P53618,P62899,P48444,P43034,Q6W2J9,Q15058,P42858,Q14738,Q93008,Q2VPK5,P49589,Q9UBB6,O75179,O95630,Q15042 72 +Neoplasm of the pancreas 0.2221137537007252 0.0924689696732594 0.9263254441818884 1.0 1.0 25 P60866,P54277,Q01844,Q9BUR4,P11802,P42771,P52701 7 +Abnormality of earlobe 0.222942045414176 0.0924627953602428 0.9263303495557058 1.0 1.0 28 O60701,Q15392,O14802,Q96N67,P28482,Q13535 6 +Abnormality of reproductive system physiology 0.2393554685616043 0.0924310011283718 0.9263556095102764 1.0 1.0 147 Q16740,P49770,O00170,Q9BUK6,P18074,Q06787,Q3SYG4,Q14999,P22681,P57076,O00429,P40763,P40818,P28340,Q4J6C6,P31751,Q13144,P48449,P49327,Q6W2J9,Q07864,P42858,Q15042 23 +Thoracic kyphosis 0.2099499725658184 0.0916848866779261 0.9269484054941416 1.0 1.0 15 O43776,P18074,P26639 3 +Language impairment 0.2423050565871659 0.0916024342099047 0.9270139173642292 1.0 1.0 300 Q05639,Q03164,P11310,P41440,Q2M389,Q7Z392,Q7Z6Z7,Q15555,Q9BUK6,Q15813,P18074,Q9BXJ9,Q92796,Q16512,Q06787,Q14353,Q3SYG4,Q96F86,P22681,O15020,Q9BPU6,P26196,Q9Y487,P57076,O00429,Q9Y4X0,Q96D71,P61960,Q9BTW9,Q08209,Q01105,P21359,Q6IA86,Q9Y263,Q8N0X7,Q7LBC6,P10589,O43776,Q2TAL8,P04350,P07437,Q05086,Q08AM6,P48449,P28482,P57081,O75569,O95352,O75179,Q9BV10,Q96C86,Q9NUQ7,Q9UHD2,P42858,Q14738,Q69YN2,P49589,Q9UBB6,Q13501,P49419,P42356,Q969U7,P30566 63 +Abnormal jaw morphology 0.1890124628095227 0.0913344456228945 0.9272268487114972 1.0 1.0 299 P60866,Q00535,O00170,Q7Z6Z7,Q9BUR4,Q15555,Q9BUK6,Q15813,P18074,O60826,Q06787,Q14999,P22681,P62081,Q15392,Q9BPU6,O60566,O14802,P26196,P26639,P62847,P08708,Q06210,P62854,Q9Y4X0,O43318,P08243,P67870,Q9BTW9,Q08209,P28340,P21359,Q4J6C6,Q9Y263,Q92917,Q15645,O43776,Q9BSJ2,P07437,P63241,Q05086,Q08AM6,A1X283,Q06124,Q13057,P28482,P57081,O95352,Q13535,P62899,Q9BV10,Q07864,P42858,Q15058,Q2VPK5,P42356,O95630,Q15042 58 +Abnormality of finger 0.2020361305236057 0.0911041743255 0.9274098158071672 1.0 1.0 298 Q03164,P60866,O00170,Q15555,P18074,O60826,Q92796,Q3SYG4,Q14999,P22681,Q9H4L7,P62081,Q9BPU6,O14802,P38935,P62847,P08708,P62854,Q9Y4X0,O43318,Q8IWV7,P28070,Q9Y263,Q8N0X7,Q92917,Q15645,P10589,O15357,O43776,Q2TAL8,Q86TI2,P07437,Q05086,Q08AM6,P50851,A1X283,Q06124,P57081,O95352,Q13535,P62899,Q9BV10,Q6W2J9,P42858,Q69YN2,Q2VPK5,P42356,O95630,Q15042 49 +Abnormal external genitalia 0.1809206511327166 0.0911037695704266 0.9274101374175456 1.0 1.0 298 P60866,O00170,Q8NCE2,Q7Z6Z7,Q9BUR4,Q9Y3Z3,Q9C0B1,Q15555,P42771,Q15813,P18074,O60826,P22314,O96017,Q06787,Q3SYG4,Q14999,P22681,O43505,O15111,P62081,Q15392,Q9BPU6,O60566,O14802,P26196,P26639,P27635,P62847,Q9Y487,P08708,P51114,P62854,O43318,P00492,P42766,P36507,Q92620,P39019,Q8IWS0,Q9BTW9,P29372,Q8IWV7,P31939,Q9NSD9,Q9BW83,P28340,P21359,Q7LBC6,O15357,Q15645,Q08J23,P07437,P63241,P20839,Q08AM6,P48449,P49327,Q06124,P28482,P62899,Q13535,P48444,P50570,Q9BV10,P43034,Q6W2J9,Q01844,Q07864,P42858,P49589,Q93008,Q2VPK5,Q15042 74 +Abnormal peripheral myelination 0.2180331819368319 0.0909797954434245 0.9275086453654456 1.0 1.0 36 P50570,Q5TAQ9,Q92734,O95163,O96007,P26358,O60231,Q13614,O60333 9 +Type i diabetes mellitus 0.2008337797042546 0.0906705753984897 0.927754351729088 1.0 1.0 11 A5YKK6,P50851,P40763 3 +Abnormal ovarian morphology 0.221433644697262 0.0905368439779724 0.9278606169012702 1.0 1.0 30 P20585,P31751,Q3SYG4 3 +Craniofacial dysostosis 0.2688219680511102 0.0904746183742389 0.9279100628216193 1.0 1.0 5 P62854 1 +Radial bowing 0.2858422939068036 0.0902215678219424 0.9281111455758586 1.0 1.0 4 O75369,Q96L58,Q32P28 3 +Esophageal carcinoma 0.5453731343283656 0.0900019326016874 0.9282856790691834 1.0 1.0 2 Q8N9N2 1 +Abnormality of globe location 0.2083752358084969 0.0899519765791267 0.9283253771875668 1.0 1.0 293 Q05639,Q03164,P11172,P60866,Q9UID3,Q7Z6Z7,Q15555,Q96KP1,Q9BUK6,Q15813,P18074,O60826,Q16512,Q06787,P22681,O60701,P62081,Q9BPU6,O60566,O14802,P26196,P26639,P62847,Q9Y487,P08708,O00429,P62854,P36507,O43318,Q8IWS0,Q9BTW9,P29372,Q08209,P40763,Q9NSD9,P28340,Q01105,P21359,Q92917,Q8N0X7,O15357,O43776,Q2TAL8,Q08J23,O96007,O00330,Q05086,Q08AM6,P07437,A1X283,P63241,Q06124,P28482,P57081,P62899,P48444,P43034,Q96C86,P42858,Q14738,Q93008,Q2VPK5,P49589,Q32P28,Q9UBB6,Q15477,O75179,O95630,Q15042,Q9Y285 70 +Prominent nose 0.2205937341830977 0.089923195487971 0.9283482484881982 1.0 1.0 26 Q2TAL8,Q08J23,Q8N0X7,Q13535 4 +Hydrops fetalis 0.20191730532936 0.0896898544062184 0.9285336784585552 1.0 1.0 45 P60866,P62847,P08708,P62854,Q08AM6,P49327,P62899 7 +Functional abnormality of the gastrointestinal tract 0.217626204991173 0.0894939441139728 0.9286893661703484 1.0 1.0 291 Q05639,Q03164,P34949,P60866,Q14331,P54277,Q7Z392,P42771,Q15813,P18074,Q9BUF5,Q9UER7,O60826,Q96IJ6,P54136,Q9NW08,Q16512,O95394,Q9Y6D5,Q06787,P22681,Q00653,O75874,Q9BPU6,O14802,P00492,P27635,P36507,O00429,Q06210,P48735,O43318,Q96D71,P67870,Q9BTW9,P29372,Q08209,P40763,Q9NSD9,Q01105,P21359,Q9Y263,Q8N0X7,O95163,Q86TI2,P04350,Q9Y5L0,P63241,Q05086,Q08AM6,P08397,P50851,P49327,P52701,P28482,O75569,O95352,Q9BV10,Q92734,Q9UHD2,Q01844,P42858,Q13501,Q15477,P42356 65 +Leukopenia 0.1939757864359526 0.0893781392738048 0.9287813962619264 1.0 1.0 48 P60866,Q6W2J9,P62847,P08708,P62854,P40763,P62899 7 +Distal upper limb amyotrophy 0.2017964071856328 0.0892816615078288 0.9288580678575418 1.0 1.0 12 P55072,Q8TB36,Q9NR77,O60568,P41250,Q14203,Q15120,Q14315,P43243,Q13501,Q27J81 11 +Abnormal glomerular mesangium morphology 0.2136213621362109 0.0887133123681484 0.9293097525123876 1.0 1.0 19 Q12769,Q9BW27,P00813,P53621,Q6P4I2,Q8N1F7,Q92621,Q9NQW6,Q9NPF4,Q9P2R3,Q9Y5K6,Q8WUM0,P52565,O43707,O95470,Q14C86,Q8NFH4,Q27J81 18 +Digenic inheritance 0.3580173186025622 0.0876389499899312 0.9301636436504128 1.0 1.0 3 P11766,A6NHR9 2 +Abnormally folded helix 0.2143673735768857 0.0868230672728735 0.9308121518262196 1.0 1.0 21 Q9UID3,P26196,O43776,Q6W2J9,Q9Y4X0,O15111 6 +Abnormal joint morphology 0.1801470987536582 0.0864921755393001 0.931075175779232 1.0 1.0 278 Q03164,O00170,P18074,Q9Y6D5,Q14999,P22681,Q9H4L7,Q15392,Q9BPU6,O14802,P38935,P08237,Q9NR45,Q9Y487,P00492,P36507,Q06210,O43318,Q9BTW9,O60231,Q96AY3,P40763,P28070,P21359,Q92917,Q8N0X7,O15357,O95163,P63241,Q05086,Q08AM6,P50851,A1X283,P49327,Q06124,P28482,P57081,Q13535,Q9BV10,Q96BN8,Q9NUQ7,Q6W2J9,P42858,Q14738,Q15042 45 +High narrow palate 0.2137452323002419 0.0861588310800805 0.9313401570014485 1.0 1.0 37 Q6W2J9,P26639,O43318,P18074,Q08AM6,O60826,Q06124,P28482 8 +Abnormality of upper lip 0.1796833959010439 0.0860311195187221 0.9314416791278206 1.0 1.0 276 Q05639,Q03164,Q9UID3,P42695,Q7Z6Z7,Q15555,Q96KP1,Q15813,O60826,Q92796,Q14999,P22681,O60701,P62081,Q9BPU6,O60566,Q96N67,O14802,P26196,Q9Y487,P36507,Q9Y4X0,O43318,P67870,P29372,P31939,P21359,Q4J6C6,Q7LBC6,Q9Y263,O15357,Q2TAL8,Q9BSJ2,O96007,P07437,P63241,Q08AM6,Q01433,A1X283,P28482,P57081,O95352,Q9BV10,Q96C86,Q6W2J9,Q15058,P42858,Q14738,Q00534,P30566,O75179,Q15042 52 +Abnormality of upper lip vermillion 0.2240496306742618 0.0855266404665451 0.931842717031482 1.0 1.0 132 Q05639,Q03164,Q9UID3,P42695,Q7Z6Z7,Q92796,P62081,O14802,Q9Y4X0,P29372,P31939,Q4J6C6,Q7LBC6,Q9Y263,Q2TAL8,Q9BSJ2,P63241,A1X283,P28482,P57081,Q9BV10,Q96C86,Q15058,Q14738,Q00534,P30566,O75179 27 +Abnormal leukocyte count 0.2132205704249473 0.0852190461035549 0.9320872490594184 1.0 1.0 118 P60866,P00813,P18074,O95394,P22681,Q00653,P11413,P62081,P62847,P08708,P62854,P40763,P28070,Q14790,Q13432,P50851,P49327,P62899,Q9BV10,Q96BN8,Q6W2J9,Q9UHD2,P17812,Q15477 24 +Abnormality of the amniotic fluid 0.1923859421481413 0.0842678037066011 0.9328435102467074 1.0 1.0 93 Q70HW3,Q9NPF4,Q8NCE2,P22681,O60566,P26196,P27635,P51114,Q9Y4X0,Q9BTW9,Q9NSD9,Q7LBC6,O15357,Q15645,Q08AM6,Q9BV10,P50570,P43034,Q15058,P49419,Q9Y285 21 +Abnormal cortical gyration 0.2266648191912875 0.0839884548944431 0.9330656109942724 1.0 1.0 137 Q05639,Q00535,Q2M389,Q9NPF4,P42695,Q9C0B1,Q96F86,O43505,Q15392,O14802,Q9Y487,P08243,P67870,Q08209,Q01105,Q9Y263,O43776,Q08J23,Q9BSJ2,P07437,Q08AM6,P42356,P57081,Q13535,Q9BV10,P43034,Q96C86,Q9NUQ7,Q15058,Q93008,Q2VPK5,Q8TD16,Q00534,Q9UBB6,Q14204,Q15042 36 +Downslanted palpebral fissures 0.2340381956306645 0.0835785129257369 0.9333915513524502 1.0 1.0 148 Q05639,Q03164,P11172,Q9NPF4,Q7Z6Z7,Q15555,O60826,Q92796,Q3SYG4,P22681,Q15392,Q9BPU6,O60566,O14802,P26196,Q9Y487,P36507,Q9Y4X0,O43318,P39019,Q92974,Q08209,Q9BW83,P21359,Q8N0X7,Q15645,P63241,Q05086,O14646,Q01433,A1X283,Q06124,P28482,Q13535,P43034,P42858,Q14738,Q93008,Q14204 39 +Aplastic anemia 0.2049057732575491 0.0827581302460192 0.9340438620958056 1.0 1.0 9 Q9H1A4,P98170,O60934,P61011,O76094,Q9Y3A5,Q7Z2Z2,Q5F1R6 8 +Papilloma 0.1927313874517544 0.0825684159152401 0.934194715941085 1.0 1.0 11 P18074 1 +Hypoplasia of teeth 0.2130097339924363 0.0822971797307973 0.934410397063516 1.0 1.0 24 P21359,P26639,P04080,Q15436,P18074,Q8IWV7,Q01968,Q13535 8 +Secondary amenorrhea 0.2042520272094125 0.0819836401589053 0.934659722919142 1.0 1.0 17 P49770 1 +Abnormal location of ears 0.1749618678905121 0.081882446904761 0.9347401929019972 1.0 1.0 258 Q05639,Q03164,P11172,P60866,Q9NPF4,Q7Z6Z7,Q9Y3Z3,Q15555,Q96KP1,Q15813,O60826,Q3SYG4,O43505,P22681,O15111,P62081,Q15392,O14802,O60566,P26196,Q9Y487,P27635,P62847,P08708,P62854,P36507,P47897,O43318,P42766,P39019,O60231,P31939,Q8N806,Q9BW83,P21359,Q4J6C6,Q9Y263,Q8N0X7,Q92917,Q15645,O43776,Q2TAL8,Q08J23,P07437,P63241,Q08AM6,A1X283,Q06124,P28482,P62899,Q13535,P43034,Q96C86,Q6W2J9,P26640,O60568,O00203,Q07864,O15347,Q15058,Q93008,Q2VPK5,P62266,Q14738,P30566,O95630,Q15042 67 +Angiofibromas 0.2776139056034817 0.0815269458022268 0.9350228965486592 1.0 1.0 4 P52701 1 +Adenoma sebaceum 0.2776139056034817 0.0815269458022268 0.9350228965486592 1.0 1.0 4 P52701 1 +Abnormality of temperature regulation 0.2070347793331609 0.0814173105399381 0.935110082991952 1.0 1.0 113 P49770,P00813,Q8NCE2,O43772,Q9Y3Z3,Q14232,P18074,P22314,O96017,O60333,P11413,O14802,P36507,P40763,P28070,Q15645,Q13144,O95163,Q05086,P08397,P49327,P50570,Q96BN8,Q6W2J9,Q9UHD2,Q9Y5K6,Q969U7,Q14C86 28 +Abnormality of prenatal development or birth 0.2008812948340825 0.0807368143126012 0.9356512587819024 1.0 1.0 253 Q05639,P60866,Q70HW3,O43772,Q9NPF4,Q8NCE2,P42771,P18074,O60826,P22314,O96017,P22681,O15111,Q9H4L7,P62081,Q9BPU6,O60566,P38935,Q99996,O14802,P26196,P26639,P27635,P57076,P62847,Q9Y487,Q06210,P08708,Q9Y4X0,P51114,P42766,P41252,O00429,P62854,Q9BTW9,Q08209,Q9NSD9,Q4J6C6,Q7LBC6,Q92917,O15357,Q15645,Q2TAL8,P63241,Q08AM6,P49327,Q06124,P28482,Q96CU9,P57081,P62899,P51570,Q9BV10,P50570,P36507,P43034,Q15058,Q93008,Q8TD16,Q13501,P49419,Q9Y285 62 +Abnormality of digestive system morphology 0.2036957254955594 0.0798203411014069 0.9363801460820698 1.0 1.0 249 P34949,P60866,Q9UID3,Q7Z392,Q8NCE2,Q92990,Q9BUR4,P54277,P42771,Q15813,P18074,O60826,Q92796,O95394,Q9Y6D5,P22681,Q00653,P62081,Q15392,O60566,Q9Y6B6,P26196,P62847,P57076,P08708,P62854,O43318,Q8IWV7,P29372,P40763,Q9NSD9,P28340,Q7LBC6,Q15645,O14965,Q9Y5L0,P08397,Q08AM6,P20585,P50851,P49327,P52701,P28482,P57081,P62899,Q9BV10,Q6W2J9,Q01844,Q07864,Q14738,Q9Y620,Q15477 52 +Tall stature 0.1699524907438082 0.0796700506069963 0.936499679866814 1.0 1.0 54 P21359,Q9HCK8,O14802,Q9BPU6,O00170,P43034,P26196,Q7Z6Z7,P49591,P04350,Q15334,P42858,A5YKK6,P17612,Q9UPY3,Q8N806,Q9NSD9 17 +Abnormality of the pinna 0.1792026678537504 0.0795786602973141 0.9365723679955344 1.0 1.0 248 P60866,O00170,Q9UID3,Q9NPF4,Q7Z6Z7,Q15555,Q96KP1,P18074,P22314,Q16512,Q06787,Q14999,O43505,P22681,O60701,O15111,Q15392,Q9BPU6,Q96N67,P62081,O14802,Q9NR45,P26196,P26639,P27635,P62847,P08708,P62854,P36507,Q9Y4X0,O43318,P42766,P08243,P39019,Q8IWS0,Q9BTW9,O60231,Q8N806,Q01105,P21359,Q7LBC6,P10589,O43776,Q2TAL8,Q08J23,Q9BSJ2,P63241,Q9UET6,Q01433,A1X283,P48449,Q06124,P28482,P57081,P62899,Q13535,Q9BV10,Q6W2J9,O60568,O15347,Q07864,P42858,O15160,P46109,Q2VPK5,Q8TD16,P62266,P46783,Q15042 69 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2155409785045234 0.079394110715319 0.9367191528247588 1.0 1.0 247 Q03164,P60866,Q00535,Q7Z6Z7,Q15555,Q9BUK6,Q15813,P18074,O60826,Q14999,P22681,P62081,Q15392,Q9BPU6,O60566,O14802,P26196,P26639,P62847,P08708,P62854,Q9Y4X0,O43318,P08243,Q9BTW9,Q08209,P28340,P21359,Q9Y263,Q92917,O15357,Q15645,P07437,P63241,Q08AM6,A1X283,Q06124,Q13057,P28482,P57081,P62899,Q13535,Q9BV10,Q6W2J9,Q07864,P42858,Q15058,Q2VPK5,P42356,Q15042 50 +Constitutional symptom 0.1947892358929173 0.0793525148124699 0.936752237171391 1.0 1.0 247 P11310,P60866,O00170,Q70HW3,Q8NCE2,P54277,Q9BUK6,P42771,P18074,Q9UER7,Q92796,Q06787,P22681,Q00653,P11413,Q9BPU6,Q99996,P38935,O14802,O00429,P48735,P26358,Q9BTW9,P40763,P28070,P40818,P21359,Q4J6C6,Q15645,Q9Y5L0,P08397,P07741,P49327,Q06124,P52701,P28482,O75569,Q96BN8,Q9NUQ7,Q6W2J9,Q9UHD2,Q01844,Q9Y5K6,Q07864,Q13501 45 +Down sloping shoulders 0.210660146305498 0.0791047932703567 0.9369492709849184 1.0 1.0 25 Q9BPU6,P26196,Q6W2J9,Q7Z6Z7,P42858,Q8N806 6 +Atrophy degeneration affecting the cerebrum 0.1657793496982008 0.0784262078687084 0.9374890268663456 1.0 1.0 243 Q05639,Q9NX46,Q2M389,Q7Z392,Q7Z6Z7,P18074,P54136,Q9NW08,Q06787,Q96F86,Q9BPU6,Q96N67,O14802,Q9NR45,P26196,P26639,P36507,O00429,P26358,Q96D71,P61960,P67870,Q9BTW9,Q08209,Q9NSD9,Q01105,Q9Y263,Q92917,Q99707,Q08J23,O96007,O00330,Q05086,Q01433,P00374,Q9H269,O95352,Q9BY32,P43034,Q96C86,Q9NUW8,Q9UHD2,P26640,Q9NUQ7,Q14746,P42858,P49589,Q8TD16,Q9UBB6,Q13501,P30566,Q14204,O95630,Q15042 54 +Abnormal thorax morphology 0.2399653582303099 0.0783145396006343 0.9375778520556504 1.0 1.0 240 Q03164,P00813,P60866,Q14331,Q8NCE2,Q7Z6Z7,Q15555,Q9BUK6,Q15813,P18074,O60826,Q92796,Q06787,Q9Y6D5,Q14999,O60333,P22681,P62081,Q9BPU6,O60566,O14802,P26196,P26639,P62847,Q9Y487,P08708,Q06210,O00429,P62854,O43318,P36507,Q9BTW9,Q96AY3,Q08209,Q9NSD9,P21359,Q9Y263,Q92917,O15357,O43776,Q08J23,Q9Y5L0,O00330,P07437,Q08AM6,A1X283,Q06124,P28482,O95352,Q13535,P62899,Q9BV10,P50570,Q6W2J9,Q99575,P42858,Q8TD16,Q13501,P42356 59 +Ocular albinism 0.346560104256409 0.0781905238596684 0.9376764998050464 1.0 1.0 3 O00203 1 +Motor seizure 0.2002032887775993 0.0779904993695764 0.9378356103785256 1.0 1.0 107 Q05639,Q2M389,Q96F86,Q14353,O60701,Q96N67,O60566,P27635,O00429,P67870,Q9BTW9,O60231,Q08209,P40763,Q01105,O43776,Q08J23,O00330,Q05086,P28482,P43034,Q96C86,Q9NUQ7,Q14746,Q9UBB6,P49419,P42356 27 +Motor delay 0.2340674718349981 0.0778853302919712 0.937919268691922 1.0 1.0 239 Q13614,Q03164,Q9P2J5,Q2M389,Q9UID3,Q8NCE2,Q7Z6Z7,Q9H0B6,Q15555,Q9BUK6,Q9BXJ9,Q92796,Q16512,Q06787,Q96F86,O60701,Q9BPU6,P04075,P26196,Q9Y487,P27635,P00492,Q06210,P51114,Q96D71,P67870,Q92974,P40763,Q9NSD9,Q01105,Q4J6C6,Q7LBC6,Q8N0X7,O43776,Q2TAL8,Q08J23,Q8TEQ6,P04350,Q9Y5L0,O00330,Q05086,Q01433,P07437,A1X283,P48449,P57081,O75569,O95352,P53618,P51570,P48444,P50570,Q9BV10,P43034,Q96C86,Q6W2J9,Q9NUQ7,Q15058,P42858,Q14738,P49589,Q8TD16,P06737,Q9UBB6,O75179,Q14204,Q969U7,Q15042 68 +Delayed cns myelination 0.2097597455251156 0.0776086434083264 0.9381393666761536 1.0 1.0 34 O60701,Q9BY32,O43776,P49589,Q9UBB6,P49419,Q15042 7 +Abnormality of neuronal migration 0.2332974401986137 0.0775743882501488 0.9381666161873374 1.0 1.0 155 Q05639,Q00535,Q2M389,Q9NPF4,P42695,Q9C0B1,O60826,Q06787,Q96F86,Q9Y6D5,O43505,Q15392,O14802,Q9Y487,P08243,P67870,O60231,Q08209,Q01105,Q9Y263,O43776,Q08J23,Q9BSJ2,P07437,P20839,Q08AM6,P57081,Q13535,Q9BV10,P43034,Q96C86,Q9NUQ7,Q14204,Q15058,Q93008,Q2VPK5,Q8TD16,Q00534,Q9UBB6,P42356,Q15042 41 +Abnormality of the palpebral fissures 0.2197507423427134 0.0773903709904786 0.9383130006464284 1.0 1.0 238 Q05639,Q03164,P11172,P42695,Q7Z6Z7,Q15555,Q96KP1,O60826,Q92796,O95394,Q3SYG4,P22681,O60701,Q15392,Q9BPU6,O60566,O14802,P26196,Q9Y487,P27635,P36507,Q9Y4X0,O43318,Q8IWS0,Q9BTW9,Q08209,Q9BW83,P21359,Q92917,Q8N0X7,Q15645,P10589,O43776,Q2TAL8,Q08J23,Q9BSJ2,P07437,P63241,Q05086,O14646,Q08AM6,Q01433,A1X283,Q06124,P28482,Q13535,P53618,P43034,Q6W2J9,Q15058,P42858,Q14738,Q93008,Q2VPK5,Q00534,O75179 56 +Neoplasm 0.2431201625822164 0.0773341606377396 0.9383577160096817 1.0 1.0 234 P60866,P00813,O00170,Q8NCE2,P54277,Q9BUR4,Q9Y3Z3,Q15555,Q9BUK6,P42771,P18074,Q9UER7,O76094,O60826,P22314,O95394,O60333,P22681,Q00653,Q9H4L7,Q15392,O75874,O60566,P62081,P26639,P27635,P62847,P08708,P11802,Q13126,P62854,P36507,P48735,P40763,P40818,P28340,P21359,Q15126,Q14790,Q15645,O14965,Q08J23,Q9Y5L0,O00330,P08397,P20585,P07437,P50851,P49327,Q06124,P52701,Q9H269,P28482,P62899,Q13535,P50570,P30154,Q01844,Q07864,P17812,Q93008,Q9Y620,P06737,Q13501,Q15477,P53602 66 +Abnormal esophagus physiology 0.197845608153336 0.0765984541788171 0.9389429887286588 1.0 1.0 235 Q05639,Q03164,Q14331,Q7Z392,Q9BUF5,O60826,Q96IJ6,P54136,Q9NW08,Q16512,O95394,Q9Y6D5,Q06787,O75874,Q9BPU6,O14802,P00492,P36507,O00429,Q06210,P48735,O43318,Q96D71,P67870,Q9BTW9,P29372,Q08209,P40763,Q9NSD9,Q01105,P21359,Q9Y263,Q8N0X7,O95163,Q86TI2,P04350,P63241,Q05086,Q08AM6,P08397,P28482,O75569,O95352,Q9BV10,Q92734,Q9UHD2,P42858,Q13501,P42356 49 +Recurrent tonsillitis 0.5274626865671723 0.076446359836309 0.9390639876716214 1.0 1.0 2 Q13546 1 +External ear malformation 0.2027190779913497 0.0764140114203592 0.9390897226968756 1.0 1.0 20 Q15813,Q6W2J9,Q15555 3 +Eclabion 0.2071599457717707 0.0761961324005401 0.939263059643253 1.0 1.0 36 Q05639,Q96N67,Q2TAL8,P18074,Q15042,Q14999 6 +Abnormality of the neck 0.2445235516909246 0.0760780161256699 0.9393570300338774 1.0 1.0 180 Q03164,P60866,Q00535,Q9UID3,Q7Z6Z7,Q15555,P18074,O60826,Q3SYG4,Q14999,P22681,P62081,O60566,Q9NR45,Q9Y487,P62847,P36507,P08708,P62854,Q9Y4X0,O43318,P21359,Q92917,O15357,P04350,P07437,Q08AM6,A1X283,Q06124,Q9H269,P28482,O75569,P62899,Q9BV10,Q6W2J9,Q9UHD2,Q07864,Q14738,Q13501,Q15042 40 +Gastrointestinal hemorrhage 0.2085779444803108 0.0754049278867246 0.9398925384880454 1.0 1.0 32 P60866,P34949,P54277,Q9UER7,P49327,P22681 6 +Abnormal tendon morphology 0.2472773599347715 0.0752014186628272 0.940054455623013 1.0 1.0 216 P11310,P41440,P60866,Q00535,Q8NCE2,Q9NPF4,P54277,Q7Z6Z7,Q9Y3Z3,Q9H0B6,Q96KP1,P18074,O60826,Q9H4L7,Q15392,O14802,P38935,P26639,P27635,Q06210,O43318,Q8IWS0,Q9BTW9,O60231,Q96AY3,Q08209,P28070,P40763,P28340,Q9Y263,Q8N0X7,Q92917,O43776,Q08J23,Q9Y5L0,O00330,P63241,A1X283,P48449,P52701,Q13057,P28482,P57081,Q13535,Q9BV10,P50570,Q92734,Q99986,Q6W2J9,Q99575,Q15058,Q14738,P49589,Q8TD16,P42356,Q969U7,Q15042 57 +Intellectual disability mild 0.2170655347113852 0.075200341948983 0.9400553122906364 1.0 1.0 133 O75182,Q05639,Q2M389,Q7Z6Z7,Q9BUK6,P54136,Q9NW08,Q06787,Q96F86,O15020,Q9BPU6,O14802,P00492,O43318,P67870,Q08209,Q01105,P21359,Q8N0X7,Q05086,Q06124,Q9H269,Q96C86,Q9NUQ7,Q6W2J9,P42858,P49589,Q00534,Q9UBB6,Q15477 30 +Oval face 0.225112107623328 0.0748823639035952 0.9403083087215524 1.0 1.0 7 Q9Y4L1,Q96L58,Q96KP1,O14936,Q01082,Q9UHX1 6 +Duplicated collecting system 0.2387833134906056 0.0747968729816486 0.9403763298491614 1.0 1.0 6 P28482,Q9Y4R8,P41252 3 +High palate 0.2203937838316336 0.0747499965356198 0.9404136274292074 1.0 1.0 226 Q03164,P60866,Q9UID3,Q9NPF4,Q7Z6Z7,Q9BUK6,P18074,O60826,Q92796,P22314,O95394,P22681,P62081,Q9BPU6,P26196,P26639,P62847,Q9Y487,P08708,Q06210,P62854,P36507,O43318,P42766,P39019,P29372,Q92974,P40763,Q8N806,Q9NSD9,Q01105,P21359,Q9Y263,Q2TAL8,Q08J23,P07437,O00330,Q08AM6,A1X283,Q06124,P28482,P57081,O95352,Q13535,P53618,P62899,P48444,P43034,Q6W2J9,P42858,O15160,Q93008,Q2VPK5,P46109,P62266,Q9UBB6,Q14738,Q15042 58 +Abnormality of the musculature of the lower limbs 0.2056283752718468 0.0743020542107331 0.9407700425281462 1.0 1.0 25 Q96IJ6,P50570,Q14331,Q8NCE2,Q7Z392,O60231 6 +Hypoplasia of the corpus callosum 0.2455548906298139 0.074019569238984 0.9409948139724592 1.0 1.0 198 Q05639,Q2M389,Q9UID3,Q7Z6Z7,Q9Y3Z3,Q15555,Q96KP1,Q15813,P54136,Q9NW08,Q96F86,Q9Y6D5,Q96N67,O60566,O14802,Q9NR45,P26196,P36507,Q96D71,P08243,P67870,Q9BTW9,Q08209,Q01105,P21359,Q9Y263,P10589,O43776,Q08J23,Q9BSJ2,O96007,O00330,Q05086,Q01433,P07437,A1X283,P48449,Q13057,Q9BV10,P43034,Q96C86,Q6W2J9,Q9NUQ7,P26640,Q14746,P49589,Q93008,Q8TD16,Q9UBB6,P49419,Q14204,O95630,Q15042 53 +Clonus 0.2068605573966649 0.0739181334258794 0.9410755269332264 1.0 1.0 28 Q01433,Q8N0X7,P40818 3 +Flat occiput 0.199406818776173 0.0736481695363985 0.941290341435373 1.0 1.0 20 O15357,Q05086,P62266,A1X283,P30566,Q01968,P52732 7 +Hypertelorism 0.2157907751392141 0.0731354745856572 0.9416983125959566 1.0 1.0 219 Q03164,P11172,P60866,Q9UID3,Q7Z6Z7,Q15555,Q96KP1,Q15813,P18074,O60826,P22681,P62081,Q9BPU6,O60566,O14802,P26196,Q9Y487,P62847,P36507,P08708,P62854,O43318,Q9BTW9,P29372,Q08209,P40763,Q01105,P21359,Q8N0X7,O15357,O43776,Q2TAL8,O96007,P07437,P63241,Q08AM6,A1X283,Q06124,P28482,P57081,P62899,P42858,Q14738,Q2VPK5,Q9UBB6,Q15477,O95630 47 +Abnormality of the philtrum 0.1757365703983067 0.0726714984994179 0.9420675294648132 1.0 1.0 218 Q03164,Q9UID3,Q7Z6Z7,Q15555,Q96KP1,Q15813,O60826,Q92796,Q14999,P22681,O60701,Q9BPU6,O60566,Q96N67,O14802,P26196,Q9Y487,P36507,O43318,P67870,P29372,P21359,Q9Y263,O15357,Q2TAL8,Q9BSJ2,O96007,P07437,Q08AM6,A1X283,P28482,P57081,O95352,Q9BV10,Q6W2J9,P42858,Q14738,P30566,O75179,Q15042 40 +Hepatic fibrosis 0.2058818286697515 0.0725464781467102 0.9421670186712068 1.0 1.0 31 P34949,Q3SYG4,Q15477 3 +Localized skin lesion 0.1897851484482914 0.0724583749323964 0.9422371303486784 1.0 1.0 217 Q03164,O00170,Q92990,Q7Z6Z7,Q9BUR4,Q15555,P42771,P18074,O60826,Q06787,O95394,Q9Y6D5,O60333,P22681,Q9H4L7,Q15392,Q9BPU6,O60566,O75874,O14802,P26196,P27635,P36507,P11802,Q13126,P48735,O43318,Q92620,Q8IWV7,Q96AY3,P40763,P40818,P28340,P21359,Q15126,Q15645,Q08J23,P20839,A1X283,P49327,Q06124,P52701,P28482,P53618,P43034,Q6W2J9,P42858,Q15477 48 +Abnormality of neutrophils 0.1839647106182589 0.0724174953478815 0.9422696620748277 1.0 1.0 91 P41440,P60866,Q9BUR4,P18074,O95394,P22681,P62081,P26639,P62847,P08708,P62854,P42766,P39019,P40763,Q08J23,P50851,P49327,P62899,P00491,Q96BN8,Q6W2J9,Q9UHD2,O00203 23 +Slanting of the palpebral fissure 0.231317057852012 0.0716736052779033 0.9428616620614392 1.0 1.0 207 Q05639,Q03164,P11172,P42695,Q7Z6Z7,Q15555,Q96KP1,O60826,Q92796,Q3SYG4,P22681,Q15392,Q9BPU6,O60566,O14802,P26196,Q9Y487,P36507,Q9Y4X0,O43318,Q9BTW9,Q08209,Q9BW83,P21359,Q8N0X7,Q15645,P10589,O43776,Q2TAL8,Q9BSJ2,P07437,P63241,Q05086,O14646,Q08AM6,Q01433,A1X283,Q06124,P28482,Q13535,P53618,P43034,Q15058,P42858,Q14738,Q93008,Q2VPK5,Q00534,O75179 49 +Abnormal c peptide level 0.2666886993646727 0.0715422800835411 0.9429661761043984 1.0 1.0 4 O00330 1 +Abnormal hemidiaphragm morphology 0.5191044776119487 0.0709608066914638 0.943428948550256 1.0 1.0 2 Q9Y223 1 +Melanoma 0.1922396304332644 0.0706739479613521 0.9436572554918096 1.0 1.0 18 P42771,P18074,P11802,Q06124 4 +Frontotemporal dementia 0.1741382730897258 0.0705993059739618 0.9437166627887608 1.0 1.0 10 Q13501 1 +Abnormality of salivation 0.1915738533907102 0.0704574566616496 0.9438295610232816 1.0 1.0 44 O14802,Q8N0X7,Q9UHD2,Q05086,Q08AM6,Q13501,Q92796,P42356 8 +Porencephalic cyst 0.233206632881074 0.0691280011481828 0.944887732642864 1.0 1.0 6 Q9Y3Z3 1 +Abnormal pulmonary interstitial morphology 0.2016018133659656 0.0686752078201754 0.9452481528940866 1.0 1.0 31 P57076,Q86TI2,Q13432,P49327,P40763 5 +Abnormal intestine morphology 0.215377423642628 0.0686146742650971 0.9452963380219994 1.0 1.0 197 P34949,P60866,Q9UID3,P54277,Q9BUR4,P42771,Q15813,P18074,O60826,Q92796,P22681,P62081,Q15392,Q9Y6B6,P62847,P57076,P08708,P62854,O43318,Q8IWV7,P40763,Q9NSD9,P28340,Q7LBC6,Q15645,O14965,Q9Y5L0,P08397,P20585,P50851,P49327,P62899,Q9BV10,Q6W2J9,Q01844,Q07864,Q9Y620,Q15477 38 +Abnormal erythrocyte morphology 0.1805180194316729 0.0685477289784924 0.9453496271655396 1.0 1.0 200 P41440,P00813,Q9P2J5,P11172,P60866,Q9P0J0,Q9BUR4,Q15813,P18074,Q9UER7,P27708,P22314,O95394,O60333,P22681,Q00653,P11413,O75874,P62081,P04075,P08237,Q9Y6B6,P26639,P62847,P00492,P08708,O00429,P62854,P48506,Q9Y4X0,P48735,P42766,Q8IWV7,P40763,P28070,Q9NSD9,Q99707,Q08J23,O00330,P00374,P50851,P49327,Q96CU9,P62899,Q6W2J9,Q9GZT9,Q01844,Q969U7,Q9Y285 49 +Abnormality of muscle size 0.1956013056067738 0.0681951687267497 0.9456302728177092 1.0 1.0 198 P11310,Q14331,O00170,Q8NCE2,Q7Z392,Q7Z6Z7,Q9H0B6,Q9C0B1,Q9BUK6,Q15813,P22314,Q3SYG4,O60333,O14802,P38935,P08237,Q9Y487,O00429,Q06210,Q13126,O43318,Q8IWS0,Q9BTW9,O60231,P40818,Q9BW83,Q8N0X7,Q5TAQ9,Q05086,Q01433,Q13057,P46976,P50570,Q92734,Q99986,Q9NUW8,Q9UHD2,Q99575,P49589,Q8TD16,Q13501,P30566,Q14204,Q969U7,Q13614 45 +Abnormal delivery 0.1932058632383512 0.0671589700261278 0.9464551485193936 1.0 1.0 22 Q8NCE2,Q9Y487,Q7LBC6 3 +Torsion dystonia 0.3304067761076456 0.0671468044302997 0.9464648333988092 1.0 1.0 3 P04350 1 +Abnormality of circulating enzyme level 0.1846685108666125 0.0669908061498315 0.9465890223888522 1.0 1.0 97 P11310,Q92734,Q8NCE2,O43772,Q2TAL8,Q06210,Q9BUK6,Q9BTW9,O60231 9 +Aplasia hypoplasia of the extremities 0.1959026956080373 0.0668805520610823 0.9466767955747396 1.0 1.0 192 Q03164,P00813,P60866,Q7Z6Z7,Q15555,Q15813,O60826,Q92796,Q06787,Q14999,O15111,P62081,Q15392,Q9BPU6,O75874,O14802,Q9NR45,P26196,P27635,P62847,P08708,P62854,P48735,Q9Y4X0,O43318,P42766,P39019,Q8IWS0,Q96AY3,Q8N806,Q8N0X7,O15357,Q9Y4P8,Q08J23,Q08AM6,A1X283,P28482,P62899,Q13535,P48444,Q9BV10,Q6W2J9,Q99575,Q07864,P42858,Q93008,Q32P28,Q14204,O95630 49 +Infantile onset 0.1751851581476669 0.0667056338834648 0.9468160491140682 1.0 1.0 192 Q05639,Q70HW3,Q9P0J0,Q7Z460,Q7Z6Z7,Q96KP1,Q15813,Q16512,Q96F86,Q9Y6D5,O15020,Q96N67,Q9Y6B6,Q06210,P62854,Q9Y4X0,Q9BTW9,P40763,Q9NSD9,Q99707,O43776,Q9BSJ2,P20839,Q96CU9,O95352,Q9BY32,Q96BN8,Q14746,Q69YN2,Q9UBB6,P30566,Q969U7 32 +Abnormal vagina morphology 0.1923422296029236 0.0666032561528748 0.9468975534690068 1.0 1.0 22 O60566,Q15645,Q6W2J9,O43684,Q15058,O15160,Q8IWV7,O43683 8 +Abnormal enzyme coenzyme activity 0.1953251140453468 0.0655753900821052 0.9477158827997392 1.0 1.0 186 P11310,P34949,P00813,O75880,P41440,P11172,P60866,O43772,Q96C23,P42771,Q9UER7,P22681,Q00653,P62081,Q9Y6B6,P62847,P08708,P62854,Q96AY3,P28070,P28340,Q99707,Q9Y5L0,O96007,P08397,P07741,P62899,Q9BV10,Q13501 29 +Periorbital edema 0.1957746228225041 0.0654191809526587 0.947840252599296 1.0 1.0 27 O00170,Q14331,Q9Y5K6,Q14C86,P28070 5 +Abnormal macroscopic urine appearance 0.1853185801896003 0.0652702009602891 0.9479588679249578 1.0 1.0 19 P53004,P08397,Q9Y5K6 3 +Abnormal finger phalanx morphology 0.2130367026966133 0.0651694359736061 0.9480390959405548 1.0 1.0 177 Q03164,P60866,P18074,O60826,Q92796,Q3SYG4,Q9H4L7,P62081,Q9BPU6,P38935,P62847,P08708,P62854,Q9Y4X0,O43318,Q9Y263,Q92917,Q08AM6,A1X283,P57081,P62899,Q13535,Q6W2J9,P42858,Q69YN2,O95630,Q15042 27 +Pain 0.2080686327431443 0.0650553100923452 0.9481299623951788 1.0 1.0 180 P11310,P60866,O00170,Q70HW3,Q8NCE2,P54277,Q9BUK6,P42771,P18074,Q9UER7,Q06787,P22681,Q00653,P11413,O14802,O00429,P48735,P40763,P28070,P40818,P21359,Q15645,P08397,P07741,P49327,Q06124,P52701,O75569,Q96BN8,Q9NUQ7,Q6W2J9,Q9UHD2,Q01844,Q07864,Q13501 35 +Puberty and gonadal disorders 0.2150982460708216 0.0650093141758618 0.9481665843041434 1.0 1.0 156 Q16740,P49770,O00170,Q7Z6Z7,Q15555,P18074,Q9NW08,Q06787,Q3SYG4,P22681,O75874,Q9BPU6,O14802,P26196,P27635,O00429,P48735,O43318,Q92620,Q8IWS0,P40763,P28340,P21359,Q4J6C6,Q13144,P63241,P20839,P48449,Q06124,Q07864,P42858,P49589,P06737,Q15042 34 +Abnormality of fluid regulation 0.2093858857370924 0.0645662567279483 0.9485193518577044 1.0 1.0 176 P11310,P34949,P00813,P60866,Q00535,Q14331,O00170,Q9UID3,Q15555,P22681,P62081,P62847,P36507,P08708,P62854,P26358,Q8IWV7,P40763,P28070,P40818,Q9NSD9,Q9Y263,O15357,Q15645,P07437,Q08AM6,P49327,Q06124,P28482,P62899,Q9BV10,Q96BN8,Q9UHD2,Q9Y5K6,Q969U7 35 +Muscle stiffness 0.1857743097238774 0.064549096033552 0.948533015607966 1.0 1.0 20 P07602,P06753,Q9NQX3,Q9Y3Z3,P23786,Q15392,Q9NW15,Q5TBB1,P00338,P11166,Q12756,P55265,P49748,Q8NBU5,Q9NZJ7,P53985,O75792,P46020,P52732 19 +Abnormal circulating protein concentration 0.214368366633889 0.0644801834866164 0.9485878855581288 1.0 1.0 160 P11310,P34949,P41440,Q14331,Q8NCE2,Q7Z392,O43772,Q9NPF4,Q9BUK6,P22314,O43505,Q9Y6B6,Q9Y487,Q06210,Q8IWV7,Q9BTW9,O60231,Q9NSD9,Q2TAL8,Q08J23,Q9Y5L0,O00330,P57081,Q9BV10,P50570,Q92734,Q96BN8,Q9NUW8,Q9UHD2,Q9Y5K6,Q14746,Q13501,Q14C86,Q9Y285 34 +Epicanthus 0.2010954403321649 0.0641919313503277 0.9488174019956503 1.0 1.0 178 Q05639,Q03164,P60866,Q9UID3,Q9NPF4,Q7Z6Z7,Q15555,P18074,P22681,O60701,P62081,Q15392,O60566,P04075,Q9NR45,P26196,P26639,P27635,P62847,Q9Y487,P08708,P62854,P36507,P47897,P42766,O60231,P21359,Q4J6C6,Q8N0X7,Q15645,P10589,Q08J23,P07437,O00330,Q05086,P63241,Q06124,P28482,P57081,P62899,Q9BV10,P43034,Q9UBB6 43 +Lacrimation abnormality 0.1825585852972656 0.063807690484216 0.9491233546191418 1.0 1.0 19 Q03001,Q7Z392,O95163,Q15056,Q8IWV7,Q96IJ6 6 +Muscular hypotonia of the trunk 0.169219683612101 0.0637915818238761 0.9491361813390408 1.0 1.0 80 O60701,Q6IA86,O75880,P26196,Q08J23,Q9Y3Z3,P04350,Q9BSJ2,P42858,O00330,Q01433,P08243,P54136,O95352,Q9NSD9 15 +Reduced tendon reflexes 0.1827183409564134 0.0633808170250014 0.9494632623313568 1.0 1.0 177 Q05639,P11310,P41440,Q00535,Q8NCE2,Q7Z392,Q9H0B6,Q9BUK6,P18074,P22314,Q06787,O95394,O43505,O60333,O60701,P38935,Q9Y6B6,P26639,O00429,Q06210,P51114,P26358,Q9BTW9,O60231,Q96AY3,Q92974,Q08209,Q5TAQ9,O43776,Q2TAL8,Q8TEQ6,O95163,Q13057,P50570,Q92734,Q9NUW8,Q9UHD2,Q14738,Q8TD16,Q13501,Q14204 41 +Abnormality of the thyroid gland 0.1926072802004283 0.0631891797826709 0.949615860844054 1.0 1.0 114 P34949,P00813,P60866,O00170,P54277,Q9Y3Z3,Q9BUK6,P42771,Q06787,O75874,O14802,O60566,O00429,P48735,Q8IWV7,P40763,Q9Y263,Q15645,Q9Y5L0,P20585,P50851,P49327,P52701,P57081,Q6W2J9,Q15477 26 +Short digit 0.2093222135366905 0.0629688745728919 0.9497912896094975 1.0 1.0 158 Q03164,P00813,P60866,Q7Z6Z7,Q9C0B1,O60826,Q92796,O95394,Q3SYG4,Q14999,P22681,P62081,Q9BPU6,P26196,P27635,P62847,P08708,P62854,O43318,P42766,P39019,Q8IWS0,Q08209,Q8N806,Q8N0X7,O15357,Q9Y4P8,Q08J23,Q08AM6,Q9UET6,A1X283,P48449,Q06124,P28482,P62899,Q96C86,Q6W2J9,Q99575,P42858,Q93008,P46109,O95630 42 +Exodeviation 0.1888453064881129 0.0629646707053576 0.9497946371676932 1.0 1.0 24 P10589,Q7Z392,Q05086,Q6W2J9 4 +Skeletal muscle atrophy 0.2039462892561809 0.0627875504422755 0.9499356796161144 1.0 1.0 168 P11310,Q14331,O00170,Q7Z392,Q7Z6Z7,Q9H0B6,Q9BUK6,Q15813,P22314,Q3SYG4,O60333,O14802,P38935,P08237,O00429,Q06210,Q13126,Q8IWS0,Q9BTW9,P40818,Q9BW83,Q8N0X7,Q5TAQ9,Q01433,Q13057,P46976,P50570,Q92734,Q99986,Q9NUW8,Q9UHD2,P49589,Q8TD16,Q13501,P30566,Q14204,Q969U7,Q13614 38 +Abnormality of the nasal alae 0.1699190240213888 0.0625890877223574 0.9500937191168692 1.0 1.0 174 Q9UID3,Q7Z6Z7,Q15555,P18074,Q92796,Q14999,Q15392,Q96N67,O60566,O14802,Q9Y487,P36507,Q9Y4X0,O43318,Q92620,Q8IWV7,P29372,P31939,P21359,Q7LBC6,O15357,P10589,Q2TAL8,Q08J23,P63241,P20839,Q08AM6,A1X283,P28482,P57081,P43034,Q6W2J9,Q15058,P30566,O75179,Q15042 36 +Abnormality of the musculature of the limbs 0.2026498486445943 0.0622193367176674 0.9503881638486876 1.0 1.0 165 Q05639,P60866,Q14331,Q8NCE2,Q7Z392,P42695,Q15813,Q96IJ6,P54136,Q14999,P62081,O14802,P38935,Q9Y487,P62847,P08708,Q06210,Q13126,O00429,P62854,O43318,O60231,Q08209,P40818,P21359,Q9Y263,Q8N0X7,Q9Y5L0,P08397,Q00796,Q06124,P62899,Q92734,Q9NUW8,Q13501,P42356 36 +Abnormal circulating bilirubin concentration 0.1913481220819747 0.0621287728674881 0.9504602838177424 1.0 1.0 28 Q9Y5L0,P11413,P41440,P08237 4 +Diminished movement 0.1788741958071532 0.0620404037649516 0.9505306564040794 1.0 1.0 19 Q6Y7W6,P51114,P42858,Q14203,O75165,Q04637 6 +Scleral staphyloma 0.3213043224714796 0.0619976188378388 0.9505647282475556 1.0 1.0 3 P36404 1 +Facial edema 0.1907340553550023 0.0617650776905711 0.9507499143319896 1.0 1.0 28 Q9BW27,Q9Y4P3,O00170,Q14331,Q9NQW6,P35250,Q15056,O43709,Q9H1A4,Q9P2R3,P78347,Q8WUM0,P52565,Q8NFH4,P28070,Q27J81,Q12769,A6NHR9,Q12756,P50542,Q8N1F7,Q92621,P57740,Q01082,Q9Y5K6,O43707,Q14C86 27 +Wide nasal bridge 0.1855115493829598 0.0613094192502414 0.9511127894388204 1.0 1.0 167 Q03164,P11172,P60866,Q7Z6Z7,Q15555,Q96KP1,P18074,O60826,P62081,Q9BPU6,P26196,Q9Y487,P27635,P62847,P08708,P62854,O43318,P29372,P40763,Q01105,P20839,A1X283,Q06124,P28482,P62899,Q15058,P42858,Q15477,Q15042 29 +Parkinsonism 0.1908544274763611 0.0611094246023795 0.9512720634332448 1.0 1.0 30 Q9Y3I1,Q6Y7W6,Q9UHD2,Q14203,O75165,Q13501,Q04637,Q13057,Q06787,O75569 10 +Clinodactyly 0.2024788842144377 0.0610096383823321 0.9513515330374775 1.0 1.0 151 O75182,Q03164,Q7Z6Z7,O60826,Q92796,Q14999,P22681,Q9BPU6,O60566,P26196,Q9Y4X0,O43318,Q8IWV7,Q8N0X7,Q15645,O43776,Q2TAL8,Q05086,A1X283,Q06124,P28482,P57081,O95352,Q13535,Q9BV10,Q6W2J9,Q07864,P42858,O95630 29 +Full cheeks 0.1897567755557954 0.0604864475446425 0.9517682093792276 1.0 1.0 37 Q9P2J5,Q00535,O00170,P36507,O96007,Q15813,O43318,P41252,A1X283,Q01968,P54577,P52732 12 +Aplasia hypoplasia involving bones of the upper limbs 0.1994068160753771 0.0603498741187386 0.9518769804992492 1.0 1.0 152 Q03164,P60866,Q7Z6Z7,Q15555,Q15813,O60826,Q92796,Q06787,Q14999,O15111,P62081,O14802,Q9NR45,P27635,P62847,P08708,P62854,O43318,P42766,P39019,Q8IWS0,Q96AY3,O15357,Q9Y4P8,Q08J23,Q08AM6,Q9UET6,A1X283,P28482,P62899,Q13535,Q9BV10,Q6W2J9,P42858,Q93008,P46109,Q32P28,Q14204,O95630 39 +Muscular dystrophy 0.1832354332569437 0.0601005945868303 0.9520755164091874 1.0 1.0 24 Q9Y617,O60566,Q14331,Q15645,Q7Z392,Q9Y5L0,O43505 7 +Neonatal alloimmune thrombocytopenia 0.2501677652721932 0.0595344994967674 0.9525263875736536 1.0 1.0 4 Q9Y3Z3 1 +Chronic lymphatic leukemia 0.2501677652721932 0.0595344994967674 0.9525263875736536 1.0 1.0 4 Q9Y3Z3 1 +Moyamoya phenomenon 0.2501677652721932 0.0595344994967674 0.9525263875736536 1.0 1.0 4 Q9Y3Z3 1 +Chilblains 0.2501677652721932 0.0595344994967674 0.9525263875736536 1.0 1.0 4 Q9Y3Z3 1 +Chronic leukemia 0.2501677652721932 0.0595344994967674 0.9525263875736536 1.0 1.0 4 Q9Y3Z3 1 +Short attention span 0.1972888996346865 0.0595007034175044 0.9525533052254628 1.0 1.0 142 O75182,Q05639,Q03164,P60866,Q2M389,P54277,Q7Z6Z7,Q9BXJ9,Q92796,Q06787,Q96F86,Q9BPU6,Q08209,P21359,Q7LBC6,P10589,Q05086,P52701,P28482,Q96C86,Q9NUQ7,Q15058,P42858,P49589,Q9UBB6,O75179 26 +External genital hypoplasia 0.192720878808006 0.0587138374272031 0.9531800376796284 1.0 1.0 129 Q7Z6Z7,Q9Y3Z3,Q15555,Q15813,P18074,O60826,P22314,Q06787,Q3SYG4,O43505,Q14999,Q9BPU6,O60566,P26196,P27635,P51114,O43318,Q92620,Q8IWV7,Q8IWS0,Q9BW83,P07437,P20839,Q08AM6,P48449,Q06124,P48444,Q9BV10,P43034,Q07864,Q2VPK5,Q15042 32 +Joint hyperflexibility 0.178063399527849 0.0569023630251203 0.9546229719431484 1.0 1.0 44 Q08J23,Q05086,Q06124,Q13535,Q8IWS0,P28482,P40763,Q14999,P22681 9 +Abnormal serum interferon level 0.2174910579359787 0.0559436431305092 0.9553867030578128 1.0 1.0 6 Q9Y3Z3 1 +Restlessness 0.1825483996690972 0.0558589930302936 0.9554541386168424 1.0 1.0 37 Q6Y7W6,Q9UHD2,P42858,Q14203,P08397,O75165,Q6PJG6,P48449,Q04637,Q13501,P07737,P49419,P52732 13 +Bilateral sensorineural hearing impairment 0.177294552688686 0.0554128377687851 0.9558095684920412 1.0 1.0 28 Q96I59,Q9UHD2,P26639,P18074,Q13501,O95352 6 +Abnormal ileum morphology 0.1432424333233366 0.0553088915128099 0.955892378608248 1.0 1.0 15 P51608,P51812,Q04206,Q9NVI1,O60488,Q93008,Q9UET6,P31150,Q92796,P38398,Q9BXW9,P51610,Q9BZI7,O14974 14 +Long philtrum 0.1688877352054763 0.0550433447228672 0.9561039320192476 1.0 1.0 139 Q03164,Q7Z6Z7,Q15555,Q96KP1,Q15813,Q92796,Q14999,P22681,Q9BPU6,O60566,P26196,Q9Y487,P36507,O43318,P21359,Q9Y263,O15357,O96007,P07437,P28482,Q6W2J9,P42858,Q14738,P30566 24 +Glomerulonephritis 0.1521329617030931 0.0548256468932296 0.9562773678613165 1.0 1.0 18 O95394,Q9Y5K6,P49327 3 +Abnormal pancreas morphology 0.1433283358320877 0.0541162237093222 0.9568425665370852 1.0 1.0 17 Q96T58,Q9Y4R8,Q9UBS4,Q92908,Q9Y3E5,Q9NQH7,O75369,O00330,P61011,Q9Y3A5,Q7Z2Z2,Q14697,Q9BXW9,P40763,Q5F1R6,A5YKK6 16 +Upslanted palpebral fissure 0.1684571345309052 0.053950070743021 0.9569749440389408 1.0 1.0 94 P42695,Q7Z6Z7,Q15555,Q96KP1,O60826,Q92796,O14802,O60566,O43318,Q9BTW9,P10589,O43776,Q2TAL8,Q9BSJ2,P07437,Q08AM6,P53618,Q15058,Q00534,Q2VPK5,O75179 21 +Knee flexion contracture 0.1678448243265308 0.0534596202492994 0.9573657029897682 1.0 1.0 26 Q96AY3,P27635,Q06210,Q8TD16,O60231,P22314 6 +Nephrocalcinosis 0.1607572115384601 0.0529033557378144 0.957808910650518 1.0 1.0 24 Q9Y4P3,P35250,Q15056,O43709,Q9H078,Q5F1R6,Q9UIG0,Q9H267,Q96Q11,P78347,Q9Y4X0,Q96EX3,Q6P1J9,O00443,P16930,P56589,Q9UBQ7,Q6ZRS2,Q9Y3A5,Q9UNF1,P21281,P61011,Q01968 23 +Extrapyramidal muscular rigidity 0.2124925283921032 0.0525446129112721 0.9580947484467586 1.0 1.0 6 Q9BPX6,Q9Y3Z3,O75792,Q5TBB1,Q9H6K4 5 +Progressive proximal muscle weakness 0.2326378878408357 0.05032365246866 0.9598644757017762 1.0 1.0 4 Q7Z392 1 +Nephritis 0.121933742276585 0.0502317411158919 0.959937717720259 1.0 1.0 22 P35579,Q9Y5K6,P49327,O95394,Q14C86 5 +Decreased circulating copper concentration 0.2852192419963837 0.0479117118267672 0.9617866054233042 1.0 1.0 3 Q14746 1 +Proximal symphalangism 0.4683582089552336 0.0474398064456072 0.9621627037630004 1.0 1.0 2 P48651 1 +Symphalangism affecting the phalanges of the hand 0.4683582089552336 0.0474398064456072 0.9621627037630004 1.0 1.0 2 P48651 1 +Tetraparesis 0.1494356851402399 0.0457093845515011 0.9635418838387584 1.0 1.0 37 Q9UHD2,O00330,Q15813,Q13501,O95630,Q9Y6D5 6 +Abnormal natural killer cell physiology 0.2744102717228937 0.0452841793034402 0.9638807975887538 1.0 1.0 3 O00203,P98170 2 +Tetraplegia tetraparesis 0.1491548641042676 0.04453887099367 0.9644748681326628 1.0 1.0 49 Q92734,Q9UHD2,O00330,Q15813,Q13501,Q9BTW9,O95630,Q9Y6D5 8 +Hyperphenylalaninemia 0.426865671641802 0.0376921922352584 0.9699331012684826 1.0 1.0 2 P61457 1 +Abnormal superior cerebellar peduncle morphology 0.4200000000000095 0.0366532167670347 0.970761511166107 1.0 1.0 2 P36405 1 +Elongated superior cerebellar peduncle 0.4200000000000095 0.0366532167670347 0.970761511166107 1.0 1.0 2 P36405 1 +Abnormality of the mastoid 0.3943283582089636 0.0338025390346207 0.9730346112473032 1.0 1.0 2 P29144 1 +Mastoiditis 0.3943283582089636 0.0338025390346207 0.9730346112473032 1.0 1.0 2 P29144 1 +Abnormal dlco 0.2692537313432899 0.030605663888613 0.9755840251373668 1.0 1.0 2 P53621 1 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9987bd5fcfac669213ade4752b4bff59ee06d14d --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lacrimal punctum morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasal mucus secretion", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of olfactory lobe morphology", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent lacrimal punctum", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary agenesis", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to polysaccharide vaccine", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Dumbbell shaped long bone", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased fibular diameter", "Increased head circumference", "Increased hematocrit", "Increased hemoglobin", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased pulmonary vascular resistance", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal carcinoid", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuchal rigidity", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Paraproteinemia", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior rib cupping", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment depression", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "Systolic heart murmur", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft palate", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCD3", "ABHD12", "ABHD5", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG2", "AMMECR1", "AMPD2", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APRT", "ARCN1", "ARFGEF2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "ATXN10", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS9", "BCAP31", "BCAT2", "BCKDHB", "BCL10", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "C2orf69", "CA8", "CAD", "CALD1", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CCDC22", "CCDC47", "CCNK", "CCT5", "CD2AP", "CD320", "CD3EAP", "CDC40", "CDC42", "CDC6", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CDKN2A", "CELF2", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHM", "CHMP2B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COG2", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "CORO1A", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX6B1", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTU2", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIAPH1", "DIAPH2", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGLN1", "EHHADH", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FAH", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATA6", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GMPPA", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKG", "IMPDH1", "INF2", "INPPL1", "INTS1", "INTS8", "IQSEC1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ITCH", "ITPA", "ITPR2", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIG4", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "MACF1", "MAGED2", "MALT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", 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"NONO", "NOP56", "NOVA2", "NPC1", "NPC2", "NPM1", "NR2F1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PAK1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS2", "PDXK", "PEPD", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RAD54B", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REEP6", "RELA", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", 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setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Ubiquitin mediated proteolysis 26 49 2.927430217105031 0.0034177574859435 15.723300970873789 45.52427184466019 -0.4425074011255512 0.5663604423511607 6.7734591108895215 5.642840055084454 0.9692061208914432 0.3445713266360056 0.1070124290166615 0.1056849906710493 0.166170852079367 0.00577480294094 +Purine metabolism 31 56 2.868539012270523 0.0041237233975743 18.893203883495147 54.37135922330097 -0.5930293740787947 0.5505944880008662 8.946347762009918 5.219498087789127 0.9780790440722584 0.345430047321658 1.0 1.0 0.0025160462840758 2.0076004853190616e-05 +Ribosome 34 73 2.719475219485225 0.0065385594073832 37.58980582524272 71.83252427184466 -1.1465156070967828 0.3112763158975234 13.159558265713326 1.6746570252811466 2.1898923040449123 0.3742528198975103 0.3227385738350301 0.5497322767159927 0.0513734883625045 0.0072752867951985 +Cell cycle 27 58 2.583986849998245 0.0097665518002627 13.774271844660197 51.12378640776699 0.0173991045433985 0.7535224495236807 7.363318835662017 6.012262326651711 0.6471200437086846 0.2867365157911225 0.4166735844106352 0.0961011545319798 0.1469580160680866 0.0251176832677275 +Base excision repair 6 15 2.402328099389879 0.0162910893271215 5.786407766990291 16.211165048543688 -0.2730268248762191 0.5152500921911025 3.196328249777864 2.273009980360234 1.0166543179529104 0.3267952106522383 1.0 0.275422289319612 0.0085651992096032 0.0010440793255692 +Drug metabolism other enzymes 7 9 2.376243298190079 0.0174899262709242 4.259708737864078 8.570388349514563 -0.3990600928512082 0.4716504970975876 2.449098885725028 1.025119857856174 0.986462354220944 0.3075676525624797 1.0 1.0 0.4147125777305785 0.0200033311952484 +Proteasome 28 35 2.333180749138486 0.0196386607735896 10.895631067961164 35.30825242718446 0.6639562464102341 0.4930746972205201 6.290791570409542 1.0118856061679289 1.2857516091435552 0.3675316845524202 0.1651718851687308 0.0519022265935445 0.0665120453316815 1.1813705775689822e-05 +Fructose and mannose metabolism 8 15 2.3106134524673543 0.020854215527148 6.682038834951456 14.686893203883496 -1.053147553907707 0.3319072468113807 3.0510809350586316 1.8660281942147332 1.0730261759626116 0.3075517987765541 1.0 1.0 0.1365592686609386 0.0015706126808535 +P53 signaling pathway 10 17 2.2709937790155417 0.0231473545463929 4.75 13.138349514563108 0.2179791659661161 0.5830709418085639 2.6854742308687665 2.7213262747001785 0.8499311192783285 0.3095875853329852 1.0 0.4121035132196561 0.0451787076845862 0.0053074046170533 +Nucleotide excision repair 7 23 2.268753144024993 0.0232833418238027 6.689320388349515 23.68446601941747 -0.003061475141879 0.6436791017602043 3.947542251754899 3.1209364191441753 0.7632489424193469 0.2952462494710732 0.1955906255262107 0.0721769910266099 0.0008515908739311 0.0017199102450681 +Homologous recombination 3 12 2.182040857231325 0.0291065174693778 4.012135922330097 11.152912621359222 -0.4085196930048564 0.5614987543057747 2.458855267038621 2.0535113811140597 0.7575586810248948 0.2955692419814456 0.1174219198717282 0.2256640636042331 0.0262058522408301 0.0397044670530444 +Mismatch repair 7 19 2.15678757354148 0.0310222197904201 4.83252427184466 18.160194174757283 0.0396129719955681 0.5226528038513648 3.232662558988282 1.5481175418750386 1.0072555486723271 0.3057089512016173 0.0053811669607165 0.0014183751228366 0.0002248534004763 1.0761884384293304e-05 +Jak stat signaling pathway 3 8 2.1234130555561848 0.0337192541372277 2.5388349514563107 7.325242718446602 0.1247408981464117 0.5305016303730072 1.7532069372986143 1.6446570419841182 0.9424863908946578 0.315817052482574 1.0 0.3775853910020678 0.3389320485848514 0.2236139420972091 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a5fc4add8641761205a4b16f5b7467be6f4ad024 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 17.516666666666666 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6f7db2385d0c7b094986ce54f1fbc2938c59eaaa --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fc314f0494d5828732a2c3c4ac9c7d5693747eb5 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,94 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ubiquitin mediated proteolysis 0.5330409205281432 2.927430217105031 0.0034177574859435 0.4600345078927574 0.123039269493967 49 Q15369,Q7Z6Z7,Q93034,P22314,Q13309,Q14999,P22681,Q13619,Q9NR09,O15344,Q9UBT2,P68036,P61081,P49427,P29372,Q13617,Q15386,Q9C0C9,Q8TBC4,O95071,P61086,Q9UJX4,Q05086,Q7Z7E8,A0AVT1,Q16763 26 +Purine metabolism 0.4404132553942745 2.868539012270523 0.0041237233975743 0.5246980014709302 0.1237117019272316 56 P00813,P22392,Q9NW08,P49005,P31350,P23921,Q9BUI4,P30520,O14802,Q06203,P49915,P14618,P00492,P11908,P12268,P31939,P49642,P28340,Q9P2T1,P20839,Q01433,P07741,P00491,Q9BY32,P15531,P00568,Q9UKK9,Q07864,O15160,P30566,O15067 31 +Ribosome 0.4373625315832198 2.719475219485225 0.0065385594073832 0.6929686123813723 0.1525346652837456 73 P46776,P84098,P62750,P60866,P62917,P62861,P62906,P61254,P61247,P50914,P46778,P36578,P62081,P32969,P62701,P62847,P27635,P08708,P62854,P42766,P39019,P62269,P61513,P47914,P83731,P62753,P05387,P18621,P62899,P15880,P39023,P62266,P46783,P62841 34 +Cell cycle 0.404152668227079 2.5839868499982455 0.0097665518002627 0.8290903680047952 0.1757979324047296 58 P33992,P31946,P33981,P53350,P25205,O95067,P42771,O96017,Q13309,Q13616,Q9H1A4,P27348,P63104,O60566,O43684,P11802,O43683,P33991,Q9UBD5,Q9UJX4,P20248,P30307,Q13535,Q99741,Q9UJX5,Q00534,P14635 27 +Base excision repair 0.6800938749852805 2.402328099389879 0.0162910893271215 0.9480017218038692 0.2205790278044472 15 P28340,Q07864,P09429,P29372,P49005,P18858 6 +Drug metabolism other enzymes 0.7127377842266844 2.376243298190079 0.0174899262709242 0.9582494554119624 0.2205790278044472 9 P11172,Q9BY32,Q9BZX2,P49915,P00492,P20839,P04183 7 +Proteasome 0.5844479417320686 2.333180749138486 0.0196386607735896 0.9718478378809212 0.2205790278044472 35 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 28 +Fructose and mannose metabolism 0.6633980472976393 2.3106134524673543 0.020854215527148 0.9774822741817524 0.2205790278044472 15 P34949,P04075,P09972,P08237,P17858,Q00796,Q96IJ6,Q13614 8 +P53 signaling pathway 0.652640637905898 2.2709937790155417 0.0231473545463929 0.9852351086756662 0.2205790278044472 17 Q14790,P11802,O95067,P42771,Q00534,P49327,P42574,O96017,P14635,Q13535 10 +Nucleotide excision repair 0.6354630085830759 2.2687531440249935 0.0232833418238027 0.9856005115677118 0.2205790278044472 23 P28340,P41440,P35244,Q92759,Q07864,P49005,P18858 7 +Homologous recombination 0.6433187156065466 2.182040857231325 0.0291065174693778 0.9950922160807768 0.2528944060292082 12 P28340,P49005,P35244 3 +Mismatch repair 0.6283241206724907 2.15678757354148 0.0310222197904201 0.996560563533929 0.2528944060292082 19 P28340,P41440,P35244,P49005,P20585,Q9UQ84,P18858 7 +Jak stat signaling pathway 0.69241452501162 2.1234130555561848 0.0337192541372277 0.9979174345693752 0.2528944060292082 8 P40763,P31751,P22681 3 +Regulation of autophagy 0.6723410088697517 1.888547232666941 0.0589525232712255 0.999982214084774 0.3282846062607468 7 O95352,Q9NT62,Q9Y4P1 3 +Dna replication 0.5508163109973047 1.879432140784182 0.0601855111478035 0.999985952970195 0.3282846062607468 29 P28340,P41440,P35244,P25205,Q07864,P49005,P18858 7 +Pathways in cancer 0.3428397708121984 1.8264182776954492 0.0677872807655288 0.999996743850342 0.3588738393469175 59 P62993,Q15369,P42771,Q13309,P22681,Q00653,O15111,P19174,P36507,P11802,P08238,Q13617,P40763,Q14790,Q13043,Q16204,P31751,P43246,P20585,P49327,P52701,P28482,Q04206,Q92734,P07900,Q9GZT9,P46109,Q00534,P42574 29 +Apoptosis 0.5502760339809387 1.761498599499932 0.0781540498379442 0.9999995649858576 0.3702033939692097 24 Q14790,P17655,P31751,P55212,P49327,O94919,P42574,Q08209 8 +Tgf beta signaling pathway 0.5603651338172304 1.7230634427222016 0.0848770528340323 0.9999998835068966 0.39174024384938 10 O75116,Q7Z3T8,P28482 3 +Melanoma 0.5515914113751343 1.6739506455081403 0.0941402994966169 0.9999999813375314 0.4216069520992233 10 P36507,P31751,P42771,Q00534,P28482 5 +Toll like receptor signaling pathway 0.5449262755133415 1.6527833911036325 0.0983749554898187 0.9999999919707684 0.4216069520992233 18 Q04206,P45985,Q14790,Q9UHD2,P36507,P31751,Q16539,P52564,O43318,P28482,O15111 11 +Beta alanine metabolism 0.5418784299683026 1.6149555507568865 0.1063203209893135 0.9999999983679296 0.440062798883818 13 P11310 1 +Regulation of actin cytoskeleton 0.3589953995268293 1.6003758640810757 0.1095152261531891 0.9999999991434166 0.440062798883818 53 P15311,Q9UQB8,Q13177,P60953,P41240,P46940,O75116,Q16512,Q7L576,O00401,P36507,P35241,P35579,Q13464,Q14185,Q14155,Q8TBX8,P28482,Q13153,O60610,P46109,P35080,P07737,P12814 24 +Pentose phosphate pathway 0.5381435648661202 1.5944366551884392 0.1108382679674462 0.9999999993445532 0.440062798883818 14 P11413,P04075,P09972,P08237,P36871,P17858,P11908,Q01813,P52209,O95336 10 +T cell receptor signaling pathway 0.5143318164958774 1.5872303069591212 0.1124604930480868 0.9999999995281708 0.440062798883818 27 P22681,P62993,O00221,Q04206,Q13153,Q13177,P19174,P60953,P36507,P31751,Q16539,P11802,O43318,Q02750,P28482,Q16512,Q08209,O15111 18 +Selenoamino acid metabolism 0.5243663389785848 1.5149539818437971 0.1297840583209515 0.9999999999864212 0.4686642726049079 12 Q9NZL9,P23526,O43252,O60294,P32929,P31153,Q7Z4G4,P49903 8 +Neurotrophin signaling pathway 0.4865813433627787 1.4947216746455485 0.1349870951623437 0.999999999995386 0.4686642726049079 31 P62993,P31946,O00221,P27348,P63104,Q13555,Q04206,P19174,P41240,P36507,P31751,Q16539,P46109,O14654,Q06124,P28482 16 +Basal transcription factors 0.5646884356675343 1.4770390683766923 0.1396651650296925 0.9999999999982616 0.4686642726049079 8 Q92759,P35269 2 +Pyrimidine metabolism 0.4197584097224026 1.453943132189503 0.1459620732299082 0.9999999999995368 0.4686642726049079 43 P11172,P27708,P22392,Q9NW08,P49005,P31350,P23921,Q9BUI4,O14802,P33316,P49642,P28340,P04183,P00491,Q9BY32,Q9BZX2,P15531,Q07864,P17812 19 +Oocyte meiosis 0.4212288977871155 1.4137910819161208 0.1574232528141963 0.9999999999999593 0.4686642726049079 42 P31946,P53350,O95067,Q02750,P30153,Q13616,Q9H1A4,P27348,P63104,P62136,Q9UHD1,Q08209,O43683,Q13555,O14965,Q9UJX4,P30307,P28482,Q15418,P06493,Q9UJX5,P30154,Q14738,Q9H2G2,P17612,P14635 26 +Type ii diabetes mellitus 0.551555080753444 1.4090340006453312 0.1588251146049966 0.9999999999999698 0.4686642726049079 8 P14618,O00330,P28482 3 +Chronic myeloid leukemia 0.4957433848543156 1.369567438303607 0.1708219698528914 0.9999999999999978 0.4959347511858138 20 P22681,P62993,P36507,P31751,P11802,P42771,P46109,Q00534,Q06124,P28482,O15111 11 +Mtor signaling pathway 0.4969677856481628 1.354550263914636 0.1755608887625772 0.9999999999999992 0.5016025393216493 14 P06730,P31751,Q15382,P62753,P28482,Q9Y376 6 +Erbb signaling pathway 0.487970312736609 1.3097861236142685 0.1902681987224939 1.0 0.5189132692431652 18 P62993,P45985,Q13153,P19174,P36507,P31751,P46109,P28482,Q16512,P22681 10 +Colorectal cancer 0.4841365011758706 1.2810331069732233 0.2001820376898326 1.0 0.5302139787538425 13 P28482,P20585,P31751,P52701 4 +Non small cell lung cancer 0.4840770501116946 1.2806886196471778 0.2003030586403404 1.0 0.5302139787538425 13 P19174,P36507,P31751,P42771,Q00534,P28482 6 +Glioma 0.4797618008018989 1.254097131106425 0.2098067030168147 1.0 0.5397468403490614 14 P19174,P36507,P31751,P42771,Q00534,P28482 6 +Pentose and glucuronate interconversions 0.6131781219456534 1.1793792000577723 0.2382472137783082 1.0 0.5783663442123714 4 O60701 1 +Mapk signaling pathway 0.3496233075785412 1.1786955898014282 0.2385194123982499 1.0 0.5783663442123714 49 P62993,P60953,Q99956,Q16539,Q9UER7,Q16512,O15111,Q00653,P36507,O43318,P16949,P51452,Q08209,P49407,P21359,Q13043,P31751,P49327,P28482,Q04206,Q13153,P45985,P42574,P46109,P17612 25 +Renal cell carcinoma 0.4567012568655424 1.1364137966387995 0.2557834243516108 1.0 0.5907791660657307 21 P62993,P11166,Q13153,Q15369,Q13177,Q9GZT9,P60953,P36507,P31751,P46109,Q13617,Q06124,P28482,Q16512 14 +Fc epsilon ri signaling pathway 0.4590345427099548 1.135885935398009 0.2560043052951499 1.0 0.5907791660657307 13 P62993,P45985,P19174,P36507,P31751,Q16539,P52564,P28482 8 +Acute myeloid leukemia 0.4476858331657761 1.074651822935197 0.2825306407496493 1.0 0.627845868332554 12 P62993,P36507,P31751,P28482,P40763,O15111 6 +Bladder cancer 0.503779954742263 1.0568652756118098 0.290573078165169 1.0 0.6344915264034142 7 P42771,P28482,P36507 3 +Insulin signaling pathway 0.387817613012636 1.052498076132723 0.2925710927304632 1.0 0.6344915264034142 40 P41440,Q93100,P06730,P36507,P13807,P31751,P46109,O60573,Q15382,P49327,P06737,P62753,P28482,O14654,P22681 15 +Pathogenic escherichia coli infection 0.435878348184845 1.0320786520888254 0.3020352735964033 1.0 0.6389865603549876 24 P68371,O00401,P15311,P27348,P63104,Q13464,P60953,P04350,P07437,Q9BUF5,Q13885,O75116,Q92974 13 +Prion diseases 0.5170800434001976 1.0251475358052522 0.3052935788362718 1.0 0.6389865603549876 6 P17612,P28482,P36507,Q02750 4 +Cytosolic dna sensing pathway 0.4285154401040025 0.9660168320930036 0.3340357585084277 1.0 0.6801100360838666 12 Q9BUI4,O14802,Q04206,Q9UHD2,O15160,Q9NW08,O15111 7 +Histidine metabolism 0.4629934509151743 0.951535621149754 0.3413325448754554 1.0 0.6801100360838666 8 Q7Z4G4,P49419 2 +Fc gamma r mediated phagocytosis 0.4248000884142939 0.947566839278058 0.3433500144246175 1.0 0.6801100360838666 22 O00401,P50570,P19174,P31751,O00429,P46109,P28482,Q16512 8 +Natural killer cell mediated cytotoxicity 0.4259237670715006 0.9392317010729416 0.3476117962206428 1.0 0.6801100360838666 18 P19174,P36507,P49327,Q06124,P28482,Q16512,Q08209 7 +Dorso ventral axis formation 0.5360323186486301 0.8428595336148815 0.3993070076355494 1.0 0.737107283088475 4 P62993,P28482 2 +B cell receptor signaling pathway 0.4087474771688417 0.8396687287427426 0.4010941520559541 1.0 0.737107283088475 17 P62993,O00221,Q04206,P36507,P31751,Q02750,P28482,Q08209,O15111 9 +Aminoacyl trna biosynthesis 0.3886195874273134 0.8392768601152681 0.4013139652370585 1.0 0.737107283088475 32 Q9P2J5,Q96I59,P26639,O43776,P26640,P49591,P07814,P41250,P47897,P49589,P41252,P23381,P54136,P54577,Q9Y285,Q9NSD9 16 +Pancreatic cancer 0.3994018806361477 0.7883571162982911 0.4304878472939539 1.0 0.774878125129117 16 P31751,P11802,P42771,Q00534,P28482,P40763 6 +Gnrh signaling pathway 0.3962295833586186 0.7770206795672735 0.4371465697658472 1.0 0.779073094632203 14 P62993,Q13555,P45985,P60953,P36507,P52564,Q16539,P17612,P28482 9 +Epithelial cell signaling in helicobacter pylori infection 0.383595501893772 0.7374358066200931 0.4608573673023757 1.0 0.7930547695540737 27 Q04206,P36543,Q13153,P45985,Q9Y487,P19174,Q9Y5K8,P41240,Q16539,Q93050,Q06124,P42574,Q16512,O15111 14 +Small cell lung cancer 0.3822983764026805 0.7125797862601254 0.4761058236484361 1.0 0.7944202757821747 12 Q00534,P31751,P11802,Q13309 4 +Wnt signaling pathway 0.3780951481599618 0.7042799116621766 0.4812584739198948 1.0 0.7944202757821747 27 Q13616,Q9HCK8,Q13555,Q13464,P30154,Q14738,O43318,P67870,O75116,P17612,Q08209,P19784 12 +Nod like receptor signaling pathway 0.3820993603239669 0.7006192036201699 0.4835406907324149 1.0 0.7944202757821747 14 Q14790,P07900,Q16539,O43318,P08238,P28482,O15111 7 +Riboflavin metabolism 0.4290319912786502 0.6975173945660543 0.4854790574224401 1.0 0.7944202757821747 7 Q8NFF5,Q969G6,Q13614,Q9NPH0 4 +Cysteine and methionine metabolism 0.3786402935117433 0.6726207442503339 0.5011886009485873 1.0 0.8127382718085199 17 Q99707,Q13126 2 +Metabolism of xenobiotics by cytochrome p450 0.3815957798195535 0.6350569922941406 0.5253912452905172 1.0 0.8443787870740455 9 P78417,P07099 2 +One carbon pool by folate 0.3546636372501577 0.5779950098588305 0.563267488287519 1.0 0.8840536202615676 11 Q99707,P31939 2 +Focal adhesion 0.3368182018363115 0.5757087867928569 0.5648120351671126 1.0 0.8840536202615676 36 O75116,P17655,P31751 3 +Glutathione metabolism 0.353668762147276 0.5407408011139521 0.5886862515302829 1.0 0.9017315563767158 22 P11413,O75874,P48735,P48506,P78417,P28161,P31350,P23921,P48507 9 +Pantothenate and coa biosynthesis 0.4584801039131183 0.5295613855150302 0.5964160730980543 1.0 0.9017315563767158 4 Q9NVE7 1 +Vegf signaling pathway 0.345821214078995 0.521426355222345 0.6020697957908796 1.0 0.9017315563767158 13 P19174,P36507,Q08209,P31751 4 +Thyroid cancer 0.3400780342239138 0.5155567977190617 0.606163990675459 1.0 0.9017315563767158 10 P28482,P36507,Q92734 3 +Rig i like receptor signaling pathway 0.3328944113675337 0.4552140116133406 0.6489552811598123 1.0 0.923451186911488 14 Q04206,Q13526,Q14790,Q9UHD2,Q16539,O43318,Q14258,O15111 8 +Progesterone mediated oocyte maturation 0.3298911005675007 0.4428375059759929 0.6578832726679456 1.0 0.923451186911488 28 Q9UJX5,P53350,P07900,P31751,Q16539,O95067,Q9UJX4,P20248,P08238,P30307,P17612,P28482,P14635,O43683 14 +Endometrial cancer 0.3218434298944631 0.4249420676793803 0.6708789069799326 1.0 0.923451186911488 11 P36507,P31751 2 +Adherens junction 0.325216087897445 0.4141226763241309 0.6787842664453287 1.0 0.923451186911488 27 O00401,Q9UQB8,O43318,P67870,P28482,P19784 6 +Fatty acid metabolism 0.3231420950294847 0.4091686340847366 0.6824159109695431 1.0 0.923451186911488 28 P11310 1 +Inositol phosphate metabolism 0.3185449482499966 0.386977388351937 0.698772947829339 1.0 0.923451186911488 15 P42356,Q13572,P19174,Q96PE3 4 +Propanoate metabolism 0.3190901970639445 0.3780239889983358 0.7054127733338689 1.0 0.923451186911488 25 P11310 1 +Alanine aspartate and glutamate metabolism 0.3166154104462072 0.3745714042344447 0.7079792432988075 1.0 0.923451186911488 16 Q06203,Q9NQR4,Q06210,P08243,P27708,P30566 6 +Terpenoid backbone biosynthesis 0.3022566079371279 0.3511495764752713 0.7254761364261393 1.0 0.9349577141167114 10 Q9BWD1,Q15126 2 +Prostate cancer 0.3103904333822935 0.3488667702455962 0.7271893332018866 1.0 0.9349577141167114 16 P62993,P07900,P36507,P31751,P08238,P28482,O15111 7 +Chemokine signaling pathway 0.2992260844625161 0.3221173206271153 0.7473638170742545 1.0 0.9412652238762744 32 P62993,O00401,Q04206,Q13464,Q13153,P41240,P31751,P46109,P49407,O75116,P28482,Q16512,P40763,Q8TEW0,P17612,O15111 16 +Olfactory transduction 0.6970149253731381 0.3215641218592165 0.7477829278572625 1.0 0.9412652238762744 2 Q13555 1 +Nicotinate and nicotinamide metabolism 0.368672987195944 0.3052393203012525 0.7601838871744113 1.0 0.947193519773814 5 P43490 1 +Ascorbate and aldarate metabolism 0.342787501274985 0.2946265365919069 0.7682791882609825 1.0 0.947193519773814 6 P49419 1 +Sulfur metabolism 0.6543283582089601 0.2343683564185295 0.814699022499429 1.0 0.9776388269993148 2 O95861 1 +Axon guidance 0.2763517425645362 0.214121937662711 0.8304519687263641 1.0 0.9834299629654312 27 O75116,Q16512,Q9BPU6 3 +Vascular smooth muscle contraction 0.2669952722646856 0.1995749884275526 0.8418129905798943 1.0 0.9903682242116404 16 O75116,P36507 2 +Long term potentiation 0.2555450434258143 0.1730603065881663 0.8626040248706581 1.0 1.0 15 Q13555,P36507,Q02750,P17612,P28482,Q15418,Q9UHD1,Q08209 8 +Leishmania infection 0.267970423798638 0.1626955727424571 0.8707581329855218 1.0 1.0 8 O43318,P28482,Q16539 3 +Glycolysis gluconeogenesis 0.2501415666050378 0.1461325047229327 0.8838167867839937 1.0 1.0 31 P14550,P04075,P09972,P08237,P14618,Q01813,Q96C23,P17858,P36871,P11766,P49419,P00558,P18669,P00338,P06744 15 +Adipocytokine signaling pathway 0.245684078782497 0.1360632700608273 0.8917712636825217 1.0 1.0 21 P40763,P31751,Q06124 3 +Drug metabolism cytochrome p450 0.2525340652103036 0.1314026316179881 0.8954568069852438 1.0 1.0 8 P78417 1 +Tyrosine metabolism 0.2243133825441557 0.1270372255165828 0.8989109355202449 1.0 1.0 10 Q7Z4G4 1 +Amino sugar and nucleotide sugar metabolism 0.2366971395544266 0.1164958620757875 0.9072595653559106 1.0 1.0 23 O60701,P46926,P34949,P51570,Q9NR45,Q06210,P36871,Q9UJ70,Q96IJ6,Q16222,O95394,Q13630 12 +Viral myocarditis 0.2242157256334647 0.1164101289259283 0.907327508250072 1.0 1.0 13 P35579,Q14790,O43432,Q04637,P42574 5 +O glycan biosynthesis 0.2526881720430035 0.0611429105801755 0.951245395356539 1.0 1.0 4 O43505,Q10472,Q86SF2 3 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..721e06cc11ec18cbd01702137ae02e16ced3f14c --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATR", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCKDHB", "BCL10", "BDH2", "BIRC6", "BLM", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BRCA1", "BRD8", "BRK1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "CA8", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC6", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CFL1", "CFL2", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP5", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "ESPL1", "EXO1", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA2", "GGCT", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKG", "ILK", "IMPDH1", "IMPDH2", "INPP4A", "INPPL1", "IQGAP1", "IQGAP2", "IQSEC1", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "KIDINS220", "L2HGDH", "LAMP1", "LAP3", "LARS", "LARS2", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LIG1", "LIG3", "LIG4", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAGED1", "MALT1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MCCC1", "MCCC2", "MCEE", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGAT1", "MGAT5", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NBN", "NCBP1", "NCKAP1", "NCL", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NF1", "NFKB2", "NFKBIE", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NNT", "NPC1", "NPC2", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC2", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS2", "PECR", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHF5A", "PHGDH", "PHKA1", "PHKB", "PI4KA", "PI4KB", "PIAS1", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNA1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTDSS1", "PTDSS2", "PTPN1", "PTPN11", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB13", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RALA", "RAPGEF2", "RARS", "RARS2", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHEB", "RHOA", "RIPK1", "RNASEH2A", "RNASEH2B", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEPHS1", "SETD2", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SLK", "SLTM", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORD", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAF6", "TAF6L", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBK1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TOMM40", "TP53", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TRA2A", "TRA2B", "TRAF2", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSPO", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", 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0.3729858641615031 0.4328077398558957 0.3193106634381686 0.5651633198484868 0.0347006691656239 +Dna replication pre initiation 42 61 3.60556189237112 0.000311478241278 16.987864077669904 61.73300970873787 0.4288945668380205 0.5957541730468855 9.845276246498855 3.587542857888571 1.230696609236802 0.3684137615844171 0.0086553947154521 0.0017177339571508 0.0065750114006561 3.2772030765973025e-05 +Clec7a dectin 1 signaling 39 53 3.58242336333768 0.0003404215021323 14.883495145631068 47.679611650485434 0.3802624296591366 0.5314258409805565 8.39359553685929 3.2641435107686965 1.369019650621671 0.3735312556615013 0.0583172812679527 0.0459278250864885 0.0163333865081399 1.2307067154074328e-05 +Synthesis of dna 57 82 3.541691608287942 0.0003975699915437 23.16990291262136 82.84708737864078 0.4375997809997383 0.6204468538632794 11.716110681669798 5.49919819946737 1.2425112242470815 0.3782848222763735 0.0165532224751524 0.000803652605352 0.0005008733463078 3.6119736120730846e-08 +Orc1 removal from chromatin 40 51 3.521585451780029 0.000428974387022 14.364077669902912 49.74757281553398 0.6917566411101944 0.5422658696614091 8.355189705990739 2.308567607855075 1.2721915859610031 0.3803308697876651 0.0359931946112057 0.0032218291369127 0.019727566606408 2.087888955116447e-06 +Hedgehog off state 36 52 3.4713468195065498 0.0005178546904125 15.740291262135925 51.0752427184466 0.6256619133963464 0.5308625548821857 8.054006294440956 2.7424510136822824 1.3127807939810612 0.3772173866259285 0.3595817292089537 0.2285823489212047 0.4071010928002549 0.0066637592153144 +Tcr signaling 39 52 3.464942552655016 0.0005303447544906 14.79368932038835 47.728155339805824 0.3776708616120087 0.5474588628929388 8.50292119881085 3.2417009042427978 1.3249802424411328 0.3685330173213761 0.0583172812679527 0.0459278250864885 0.0535634947283487 1.2307067154074328e-05 +Interleukin 1 signaling 39 49 3.272537007563001 0.0010658691791471 13.79368932038835 46.30582524271845 0.5021606336105483 0.5332552544880472 7.891168652335007 2.7901813019255988 1.3195993763744758 0.3779352216468381 0.3163996086563202 0.1804691418449262 0.3151345652047326 3.521476861973183e-05 +The role of gtse1 in g2 m progression after g2 checkpoint 40 50 3.2341599697976604 0.0012200109974931 14.79611650485437 48.84466019417476 0.6226477470486884 0.5168095546238419 7.820323564061835 1.8499922936255029 1.3076695437390702 0.3722860732713196 0.2669704529063582 0.1311424325427596 0.0771859011241757 1.620623892082362e-05 +Neddylation 40 74 3.176818958433708 0.0014889995501887 21.652912621359224 72.70145631067962 0.2249049893089814 0.5831751905762216 10.995736873021038 5.895588099944547 1.324302453446783 0.3688918753546149 0.2096496508421454 0.0968343783749517 0.4592727024200314 0.0038169775665278 +Cilium assembly 39 59 3.137214675607833 0.001705611931881 17.691747572815533 60.07281553398058 0.7163847705434252 0.5030560453085753 8.208427462797529 7.176657065505861 1.1196611241046792 0.3669144822823486 0.5739386056226582 0.8256872991398381 0.820552793250898 0.8854024146959705 +Mapk family signaling cascades 71 87 3.092892506664071 0.0019821591836115 23.104368932038835 88.2864077669903 0.366998662581797 0.5880023171217027 11.41393630950696 5.588694353030067 1.1675181672079205 0.3704838978698669 0.6283515613161694 0.3222065138351171 0.0319905202042186 0.0002476576016169 +Transcriptional regulation by runx2 35 51 3.000725713308664 0.0026933705582252 16.021844660194176 51.64320388349515 0.5147340657969439 0.5490234274922848 8.286848189022676 3.0091087328640205 1.321202711135219 0.3758826947187164 0.3714211816184957 0.0680937326262565 0.2196953406887221 0.0003176274883727 +Eukaryotic translation elongation 38 78 2.962600627815018 0.0030505208056206 40.33980582524272 76.70873786407768 -1.170264854227122 0.3173586097479524 13.865899638243102 1.3501604935966776 2.213815111182405 0.3781772268307828 0.3383353600617786 0.5707078240420155 0.0628592194430533 0.0011757232385209 +Degradation of beta catenin by the destruction complex 33 48 2.8912157712981004 0.0038375454338512 14.8252427184466 48.63834951456311 0.4830095996380346 0.5534777326316677 8.029589918636947 2.025992551710678 1.2813542829769398 0.3757731368449524 0.3002970578347967 0.1636927349188979 0.2821769606310413 0.000308468624942 +Dna replication 57 88 2.8757568529674904 0.0040306006374 24.50242718446602 88.36650485436893 0.2923135263536031 0.6312906600612657 12.317305449092803 5.805851117746023 1.1877285197942282 0.3655243748981305 0.025032197761541 0.0018170711193234 0.0016961074032647 6.494888416187712e-07 +Dectin 1 mediated noncanonical nf kb signaling 35 43 2.82795006532751 0.0046847113208785 12.844660194174756 41.46116504854369 0.4840649810639716 0.5219757714388732 7.477483717709433 1.5951828582954857 1.3371619060105078 0.3706757674751831 0.2176901368863651 0.0887791366891333 0.1343608611761769 3.764908963105785e-05 +Response of eif2ak4 gcn2 to amino acid deficiency 37 78 2.817982862555222 0.0048326389150989 39.550970873786405 76.03155339805825 -1.127048342201767 0.3185079045659907 13.761485019110056 1.5173669435319213 2.220942857496925 0.3803423215749384 0.3535804343497586 0.5907159409401193 0.0756775204280773 0.0018998026291165 +Fceri mediated nf kb activation 34 46 2.8164198696027043 0.0048562155318774 13.599514563106796 43.58252427184466 0.43538002101356 0.532490131621357 7.591659945968655 2.4879291964009105 1.318650463428372 0.3690692407606546 0.0390792451218721 0.0260969242847967 0.0805407528159271 9.091490665958128e-05 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 36 47 2.802992419249647 0.0050630859411768 14.026699029126211 48.65533980582524 0.5636343266746052 0.5641920682636952 7.183906351200202 2.917580729254371 1.1799230201059223 0.3753446211108022 0.2703718142220204 0.1343256297607796 0.2239304839044773 1.9164937388887257e-05 +Signaling by the b cell receptor bcr 36 51 2.781122759267146 0.0054171248577632 14.0873786407767 45.66747572815534 0.5600618981864348 0.5194725240755018 7.669263829832862 3.2521255837555954 1.3165243686049508 0.3716278052198193 0.344475156709202 0.2112534224812059 0.1753285265709659 0.0004223581342339 +Tnfr2 non canonical nf kb pathway 34 43 2.762700649807997 0.0057325314977212 12.75242718446602 41.54126213592233 0.4835600067503021 0.5236768662797463 7.499311873418453 1.6207832096977548 1.329411623900184 0.3708129323396963 0.2356515416958359 0.1033866218184072 0.1627379716452803 9.026170863058632e-05 +Mismatch repair 6 12 2.753048995198736 0.0059043059274088 3.342233009708738 11.381067961165048 0.0625185193929023 0.487617128731856 2.731844368635289 1.3892551700174145 1.035220015060314 0.3024526770428278 0.0027065615852008 0.000499833948772 3.7567527050154064e-05 7.746328029618005e-06 +S phase 61 94 2.7503614432163133 0.0059529561231965 25.58252427184466 94.497572815534 0.3936025929765626 0.6471527110395977 12.311904628033766 6.6662819095148595 1.1799446716032989 0.3778079902664983 0.0360307433300265 0.0007059888302962 0.0014817510421911 5.787687850410522e-07 +Regulation of hmox1 expression and activity 35 45 2.7429162202271864 0.0060896220178092 12.524271844660197 45.58009708737864 0.7171016159839839 0.514573723238038 7.335701580194855 2.006274620945924 1.1938232298543638 0.3651188593292154 0.2356515416958359 0.1033866218184072 0.0503151582899826 3.0095640750750782e-06 +Selenoamino acid metabolism 55 91 2.733188791614192 0.0062724367715647 45.359223300970875 88.94660194174757 -1.2269036973447986 0.3270935993226454 16.116146621354947 1.9650003351851577 2.2110932203759184 0.3833177831487697 0.3916268401133314 0.6385207456646802 0.1150221768862631 0.0347305706128729 +Nucleotide salvage 8 10 2.7154435402839447 0.0066187060888507 2.953883495145631 7.572815533980583 0.03133519647258 0.4331148618745437 2.3171604371042136 1.1791221166496233 1.162051907735956 0.3189968241349349 1.0 1.0 0.0011637071015076 2.7180346417726147e-05 +Mitotic g2 g2 m phases 51 93 2.710475131851846 0.0067186886559988 25.512135922330096 89.70388349514563 0.5564324413272281 0.5721896286221594 11.374146646790262 7.343161700072858 1.2377579618165189 0.3831596446417351 0.5799107476230156 0.5256762582418069 0.1608454547439025 0.0002645265641862 +Regulation of pten stability and activity 33 42 2.696087309438939 0.0070159274499741 12.611650485436892 41.82281553398058 0.6486618107800725 0.5229501310802542 7.056269001912706 2.1755846965350556 1.2659780846667748 0.3745012259374719 0.2532091390172839 0.0213823666458372 0.0174431156775202 7.989936247949664e-06 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 8 10 2.693900037220488 0.0070621341555678 4.609223300970874 9.12864077669903 -0.4901204318784761 0.4737638650158729 2.3192341342680676 1.017065594913464 0.9710576520697276 0.3224141412940421 0.1133242047904145 0.2182850433665622 0.1283849415189241 0.0351238878380088 +Tcf dependent signaling in response to wnt 31 64 2.682507074061641 0.0073072606350672 17.473300970873787 61.62378640776699 0.1854387909065221 0.5928765054134378 8.980116427159441 3.846157738891713 1.1264976241944151 0.36413626392076 0.4834965573348462 0.1496333865882157 0.1270873306168133 0.0014160847740268 +Interleukin 1 family signaling 41 53 2.6583300441166924 0.007852894737709 14.592233009708735 49.06310679611651 0.4308069558259447 0.5378127516815151 8.12336542865419 3.453701835311694 1.3196847762251946 0.3781683305809454 0.3565879298508765 0.2251072150562141 0.400616552648587 1.1775812714546118e-05 +Cellular response to hypoxia 32 41 2.620672289152346 0.0087756574819706 12.067961165048544 40.00485436893204 0.522970313217548 0.5163863933875538 6.981963081004602 1.736242938617286 1.3015320227429066 0.3618367398400983 0.2391950786393786 0.1063833340177388 0.1686168581594345 0.0001061774836938 +Regulation of runx2 expression and activity 31 42 2.592643949302984 0.0095241314672005 13.184466019417476 42.609223300970875 0.5014097272359687 0.5334388394290158 7.623733474716015 1.80350585730159 1.3084091861848088 0.3700608446837968 0.2462339839987873 0.1124462638013597 0.1805547601030266 0.0001452793791004 +Scf skp2 mediated degradation of p27 p21 32 40 2.5862493517843084 0.0097026710207108 12.78883495145631 40.70873786407767 0.5921499036968256 0.5162943652980111 7.12520288261254 1.2647657441579598 1.3047123749289669 0.3686628673319737 0.2213151554805003 0.0916480459892936 0.3738517588653947 4.524440963497809e-05 +Cyclin a cdk2 associated events at s phase entry 33 42 2.577907077832045 0.0099400723878657 13.196601941747574 42.85679611650485 0.6136168472607347 0.5150313285959647 7.221373891468615 2.098630488986879 1.3159566032429193 0.3694066609952225 0.3067821418395792 0.0382665496147074 0.2953338042975844 0.0003936097898921 +Downstream signaling events of b cell receptor bcr 35 48 2.5713289313177814 0.0101309052849849 13.109223300970871 42.81310679611651 0.5337893000107979 0.5120527765027618 7.35013455914348 2.784583610128895 1.330630298725885 0.3688632335833426 0.2804834813175225 0.1439779743767685 0.0910298895289141 3.1066114222159566e-05 +Mapk6 mapk4 signaling 41 49 2.553568651375436 0.0106625256710597 14.218446601941748 48.50728155339806 0.436374163749397 0.5681669850793678 8.12289402218768 1.923903139365317 1.248358570542089 0.3688600113322806 0.3002970578347967 0.1636927349188979 0.1138357711724773 0.0011526515909172 +Ub specific processing proteases 51 76 2.537699568071883 0.0111583728081865 17.070388349514563 72.1116504854369 0.5586830572298067 0.5701992170768696 9.734454714417684 6.256038651254875 1.0924507106168106 0.3735968680377643 0.5048336966026937 0.0539840939518015 0.1560139040473013 4.01261957807159e-05 +Regulation of ras by gaps 31 38 2.5221522845292546 0.0116639201321273 11.558252427184469 38.29611650485437 0.5949031665539309 0.5179046122727133 6.637200606991292 1.5039380235434 1.2829290056167597 0.3733028763215757 0.2320918530825407 0.1004140149250811 0.0477083989356381 7.642967523267423e-05 +Hedgehog on state 31 42 2.5105935363857848 0.0120528386524036 12.5752427184466 41.80339805825243 0.5567751925024539 0.5304257926517765 6.636298293339077 1.8972867972618663 1.2545866277969462 0.3643204702561447 0.2771282599295266 0.140743998387736 0.2366877859381625 0.0019108778393583 +Degradation of gli1 by the proteasome 31 40 2.503381906752321 0.0123012725018096 12.514563106796116 40.61407766990291 0.5405675752115602 0.5324758124461996 7.125251251124314 1.5545410691631658 1.272200728765061 0.3678115987415289 0.2176901368863651 0.0887791366891333 0.1343608611761769 0.0001964930706406 +Cdt1 association with the cdc6 orc origin complex 31 41 2.497471106958311 0.0125082657892905 11.8373786407767 39.713592233009706 0.7088745358379469 0.5132999135100862 6.7665841522618235 1.8864642297262784 1.2345641700762902 0.3668156388656303 0.2213151554805003 0.0141874949182814 0.0403511127078517 4.524440963497809e-05 +Degradation of dvl 30 37 2.4501568579768227 0.0142793993716767 11.50728155339806 37.79611650485437 0.5954952616194853 0.5106657090472662 6.536116642578212 1.2295647923796569 1.2774118860610646 0.3695881914917919 0.2067156970668985 0.0803423183547755 0.1182543832578025 0.0001179839212013 +Processive synthesis on the lagging strand 4 12 2.440206046258215 0.0146788868529534 5.337378640776699 12.490291262135925 -0.4682866917213784 0.4841203144335685 2.903004958430143 1.8014026122655222 0.9753460783472956 0.3256071087002858 0.0755969254036216 0.0108829135912838 0.0006049883657283 0.0010053263520343 +Negative regulation of notch4 signaling 30 39 2.427316659642882 0.0152109728229468 12.218446601941748 39.786407766990294 0.5856668642754154 0.5088435203982538 7.300807876201572 1.1247479582770583 1.3003786017754655 0.3684988575140048 0.2030241760524146 0.0775893010395362 0.3301049419756523 0.0005033411943392 +Metabolism of polyamines 30 38 2.4241665342796863 0.0153435675151196 11.783980582524272 38.49271844660194 0.5956280690899458 0.5058612771265996 6.813709458301494 1.1915745430318114 1.300721756016792 0.3709861514268986 0.1993158438352355 0.0748672511655927 0.1079489935234157 8.197910505732385e-05 +Cross presentation of soluble exogenous antigens endosomes 29 36 2.389823360727892 0.0168564777842696 11.097087378640778 36.91019417475728 0.6471378136535638 0.507052502601231 6.457500437861876 1.2421375880066114 1.2717860238430438 0.3672755762882163 0.172880472870427 0.0567506627252609 0.0749646842516762 1.908488484221945e-05 +Degradation of axin 29 36 2.389823360727892 0.0168564777842696 11.135922330097088 36.5 0.6371703324335989 0.5044883973483546 6.515923056292238 1.1005294401076644 1.2875505119575097 0.3689236351245595 0.1993158438352355 0.0748672511655927 0.1079489935234157 8.197910505732385e-05 +Regulation of runx3 expression and activity 29 36 2.386926227892392 0.0169899001879514 11.46359223300971 36.730582524271846 0.6696914114866416 0.4949350431730664 6.642474003130895 1.4202887203012589 1.288769965462232 0.3632605735082652 0.214048603403005 0.0859380278487259 0.3564761369088265 0.0001665225081846 +Negative regulation of mapk pathway 6 11 2.383234054625861 0.0171612793108202 4.233009708737864 11.558252427184469 0.0212130805321306 0.5707340991163712 2.6892590508584675 1.8963441717773477 0.8993836023547437 0.3134524971647613 1.0 1.0 0.2140290435859761 0.0071436537580251 +Asymmetric localization of pcp proteins 29 37 2.334927692114681 0.0195471984311863 11.28883495145631 37.80825242718446 0.5764639774033125 0.5188050170985335 6.482730726459962 1.1863421199640956 1.2423982841678427 0.3682278814782295 0.2213151554805003 0.0916480459892936 0.1398908463818619 0.0002308677663279 +Processive synthesis on the c strand of the telomere 3 12 2.325348467226142 0.0200533346328457 4.509708737864078 10.978155339805824 -0.4775246369782211 0.4957017371827638 2.5461569961702972 1.9895378043401617 0.8752677202336353 0.3012102484823726 0.092554689717322 0.0163998244725808 0.0014106533758772 0.017002584405276 +Eukaryotic translation initiation 48 102 2.316011925355243 0.0205576175744828 45.19417475728155 100.27669902912622 -0.7708270245582552 0.3856475380014496 15.071066765335097 1.8144888222625024 2.0151499677382354 0.3857325415106563 0.4166735844106352 0.2984400671709865 0.0067806366434166 0.0001446177959819 +G1 s dna damage checkpoints 32 41 2.301972137622654 0.0213367434972435 12.276699029126211 40.3252427184466 0.5620621733571898 0.5261130346169095 7.080750657966309 1.8659034848764728 1.2552712987328345 0.3710523646543767 0.2462339839987873 0.1124462638013597 0.1805547601030266 2.9640015944659375e-05 +Regulation of expression of slits and robos 80 123 2.2939846420050536 0.0217913809239238 48.00728155339806 122.56796116504854 -0.5194973845089386 0.4369419093856738 20.419566225634124 3.037427168561756 1.9506179546475584 0.3864092465775431 0.1598369683375962 0.1793403642996926 0.0333568849355649 1.8253496681961784e-05 +Condensation of prometaphase chromosomes 8 11 2.2930974895377005 0.0218423928951678 4.740291262135922 9.682038834951456 -0.0253462500307974 0.547816752092043 2.6102910436658395 0.7810670560615536 0.9134052717438896 0.3114594049057282 1.0 1.0 0.0274146616230463 0.0013781701696679 +Cyclin a b1 b2 associated events during g2 m transition 8 12 2.2845640474617235 0.0223384030747419 4.046116504854369 10.669902912621358 0.2479626786439341 0.5764322183879739 2.4136162020695497 1.52575526110436 0.8446083670770962 0.3089690732529406 1.0 1.0 0.442563127116907 0.0052134507581354 +Gap filling dna repair synthesis and ligation in gg ner 5 18 2.281028085876651 0.0225467849760012 5.689320388349515 18.00728155339806 -0.1316453778445818 0.5866775657255269 3.5738508947268146 2.0402373239903766 0.849036122995379 0.3001177403512302 0.1215010987245368 0.0282917804799424 0.0004806947328874 0.001918269568256 +Beta catenin independent wnt signaling 36 58 2.271452564762543 0.0231195954202951 14.62864077669903 53.63106796116505 0.2467758551278147 0.5921017130101743 7.928102596073744 3.656329241145158 1.1545689159912884 0.3649233327912332 0.4193934595654603 0.3019261892923024 0.3097939584680437 0.0111897647880177 +Regulation of mrna stability by proteins that bind au rich elements 30 62 2.269989539264924 0.0232082177451298 17.303398058252426 62.189320388349515 0.3637537395774206 0.6066390862029128 8.19973289328142 2.9201480419101515 1.0954480785949263 0.3602041660944462 0.3067821418395792 0.0382665496147074 0.041225662206046 9.891867653623074e-05 +Post chaperonin tubulin folding pathway 9 11 2.2600356646174857 0.0238190374423132 4.631067961165049 9.669902912621358 0.1824952152215168 0.5047249093477747 2.528441291450786 1.207889513967516 1.0855078483623932 0.3264088774408823 1.0 1.0 0.3547863423381785 0.0097510399506001 +Cytoprotection by hmox1 44 66 2.255322378817858 0.0241131009401294 15.264563106796116 64.83495145631068 0.939000341067099 0.4699320360831873 6.884300879212943 3.5957015529431366 1.0482386655891682 0.3835416044430508 0.4000905182293955 0.2774807318858533 0.1252670901736347 2.0461984318040226e-05 +Nonsense mediated decay nmd 51 87 2.23222881686896 0.0255998437659881 42.101941747572816 85.76941747572816 -1.1457400111181046 0.3421409039593034 15.03730946151162 2.536670214507658 2.1258465434199816 0.3829653082446096 0.4000905182293955 0.6487426398749964 0.1252670901736347 0.0069601236624558 +Purine ribonucleoside monophosphate biosynthesis 7 10 2.225076818995401 0.0260760816234768 5.609223300970874 9.57766990291262 -0.5956690698419117 0.4049019913941552 2.4976129144695394 0.4988203635714793 1.0719792910136363 0.3162446040890186 1.0 1.0 0.2348471946143729 0.0013781701696679 +Stabilization of p53 31 40 2.2127936050136645 0.026911878379092 11.759708737864075 38.849514563106794 0.5626554032387434 0.5211156380328503 6.862945949053685 1.536505541452464 1.2546862993954295 0.3691198814060923 0.210390481437923 0.0831254931938254 0.1235396851165477 2.5689600905607385e-05 +Cyclin d associated events in g1 5 9 2.183420845395713 0.0290048322290508 4.366504854368932 10.116504854368932 0.1222182547646903 0.5717022199186504 2.5273541207987025 1.6637247419470345 0.9055693104495058 0.3101665598109623 1.0 1.0 0.6660978714719568 0.1732034237667374 +Signaling by notch4 30 42 2.174550876776673 0.0296637888981525 12.74271844660194 42.689320388349515 0.5846962923720355 0.527528574888472 7.095179574371064 1.5202779907622044 1.22282479858509 0.3678962187540617 0.2804834813175225 0.1439779743767685 0.512043190605459 0.0071079189888272 +Synthesis of pc 3 6 2.170668321721831 0.0299562534543122 1.4975728155339805 5.177184466019417 0.9792901538510108 0.3349579960493364 1.1180313541111304 1.1575685242362048 0.9033750611806022 0.284045310792182 0.0967463289884207 0.1880666528119386 0.0150601402708497 0.0200033311952484 +Hdr through homologous recombination hrr 8 25 2.165502000402276 0.0303492623711116 6.589805825242719 24.111650485436893 -0.0092264701981264 0.5458067298737065 4.0672971108020715 4.028076246394997 0.9713175634602784 0.3148065661700105 0.0370108517080311 0.0034052839234269 0.0009884936930533 0.0043720646017646 +Purine salvage 5 7 2.1607337560939457 0.0307159117797584 2.111650485436894 5.288834951456311 0.197178541669856 0.4175562109566574 1.6944112000139675 0.9303781473308704 1.1388664400876831 0.3024861591528771 1.0 1.0 0.0025675639060761 0.0001575214550341 +Vitamin b5 pantothenate metabolism 3 6 2.1577037821442984 0.0309508697158578 1.8398058252427183 4.805825242718447 0.2318851509472443 0.5185415062743411 1.185907526464559 1.0686008675460108 0.903360242727704 0.3024899457304335 1.0 1.0 0.2712176839291556 0.0027630263410089 +Pten regulation 37 68 2.1411905433754583 0.0322586753367999 17.303398058252426 64.46601941747574 0.1876911775469084 0.6424585632708278 8.791141177940533 4.617012723077537 0.9726834868094096 0.3433123254029529 0.4485048795997653 0.0324980817998725 0.0879662178978236 0.0013286688444077 +Netrin 1 signaling 9 12 2.1329556617440844 0.0329283635643662 3.766990291262136 9.655339805825244 -0.1325110296822746 0.558199221376826 2.44136633515538 2.155968376812043 0.872460835405313 0.2955598798754135 1.0 0.2685126379615966 0.1876112798662428 0.0203628052401783 +G2 m checkpoints 43 88 2.131604582782838 0.0330393666989023 20.961165048543688 83.21601941747574 0.2497590522742128 0.6198120617040068 11.249096904504546 6.6438113169442845 1.0983784482763044 0.3587806160447286 0.0032853402084552 3.624801676115455e-05 0.0014358113594599 1.7565337256431588e-06 +Pcna dependent long patch base excision repair 6 18 2.123903811400572 0.0336781876310787 6.305825242718447 18.131067961165048 -0.2629874999917882 0.517441963572211 3.5188349032394246 1.8997459782268384 0.968142963238218 0.3133577308525272 0.1050728360238821 0.0211645746663273 0.0002248534004763 0.0001024209024739 +Caspase mediated cleavage of cytoskeletal proteins 4 9 2.1123167073159297 0.0346592937786645 1.970873786407767 6.145631067961165 0.1915634339305391 0.6116410183678103 1.5134113121039203 1.202002915770265 0.7791063336660976 0.293950782028581 1.0 0.1073692926764015 0.0323840811666381 0.0019884945269669 +Hedgehog ligand biogenesis 29 39 2.092000292978342 0.0364384894899858 11.735436893203884 40.279126213592235 0.705289766689403 0.5138056150617029 6.1754608769009325 1.552402214168598 1.168348102852658 0.3656259469969254 0.2176901368863651 0.0887791366891333 0.1343608611761769 0.0001964930706406 +Flt3 signaling 3 5 2.090235268223638 0.0365966708611735 1.6966019417475728 4.674757281553398 0.1447448421401304 0.5151478334177053 1.1502165717541968 0.9558423770819222 0.9684926451060778 0.307151973986046 1.0 0.2256640636042331 0.1365592686609386 0.0397044670530444 +Runx1 regulates transcription of genes involved in differentiation of hscs 22 40 2.0877071989200338 0.0368242550669233 11.74514563106796 40.9247572815534 0.4838158037368226 0.5501011058260618 6.5789160679611225 1.5190277579548277 1.1933646193238052 0.3604187581137549 0.0390792451218721 0.0260969242847967 0.0805407528159271 0.0003919277181498 +Activation of atr in response to replication stress 4 22 2.079718356469509 0.0375513733885886 5.179611650485437 19.679611650485437 0.1285647335300941 0.6575195684392049 3.862537503467055 3.0152157572513594 0.7447824953405174 0.2942694440452609 0.013156992218303 2.6152361232000373e-05 0.002019433305579 0.0093317531476842 +Maturation of sars cov 2 nucleoprotein 2 6 2.0571991691368128 0.0396670714445177 2.412621359223301 4.985436893203883 0.0067238540290333 0.5371553195215879 1.444653995706506 0.9577388182984884 0.9451900366181616 0.3092790872936227 1.0 0.1157837219692003 0.2712176839291556 0.1289341732663725 +Signaling by notch 26 57 2.0440438701890864 0.040949213409072 14.941747572815531 58.85679611650485 0.4411392402814988 0.620198315051001 7.402538586762891 3.488034668926816 0.978025139431841 0.3518651286473304 0.5071505523755517 0.4206579768151722 0.7120303007503649 0.1205744788053832 +Signaling by robo receptors 88 137 2.041017357016328 0.0412491018890048 53.89563106796116 136.44174757281553 -0.5803891128880495 0.4434346526843001 20.749810628210746 4.420166149665581 1.9093246617268536 0.3809851422615608 0.2300447920384541 0.2834997550229698 0.0481979268454476 8.186588770165123e-05 +Uch proteinases 24 46 2.0374751779433606 0.0416024469194695 12.934466019417476 45.69174757281554 0.4676332859413379 0.5268776688735902 7.345038379241775 2.489712786954197 1.2496925486564852 0.3629400025319104 0.0512049491784678 0.0382665496147074 0.12194897554883 0.0014287535135353 +Constitutive signaling by akt1 e17k in cancer 1 6 2.010631497076077 0.0443643945884142 1.9296116504854368 5.266990291262136 0.3564799056299969 0.5059420021573545 1.4934799541528836 1.8841643791539875 1.007824838624244 0.3184496724089312 1.0 0.2108364442764713 0.1203326107508497 0.3442759855295882 +Recycling of eif2 gdp 4 7 2.00176906305558 0.0453095746876823 3.313106796116505 6.905339805825243 0.1197760753571412 0.5850286119533992 2.004006438145489 0.6955270621915002 0.8511996602760747 0.3097836852205068 1.0 1.0 0.0146338936924203 0.0542215392640632 +Copi mediated anterograde transport 29 57 1.996717331075939 0.0458558983473313 14.364077669902912 53.29368932038835 0.4832864212749729 0.5898511157237575 6.303679837135847 4.572358803691129 1.0202251873333663 0.3614704266753352 1.0 1.0 0.1659238128804802 0.0667716397760765 +Transcriptional regulation by runx3 30 41 1.9934480644099355 0.0462124052017969 12.155339805825244 41.550970873786405 0.5220991170779611 0.5409180415581131 7.051829317928235 1.9320556056256075 1.205315041796802 0.3587760476843317 0.3290199976520948 0.1940719369188673 0.6162560446190544 0.0085630435153123 +Rrna processing in the mitochondrion 0 5 1.9645857272000171 0.0494622052447981 2.662621359223301 5.12378640776699 -0.6376645872438221 0.4445584700279179 1.3402872182875387 0.9304541291311428 0.8967965434996334 0.3081514224376732 0.0451714964804377 0.0903020002145616 0.2159896916124382 0.3921885014959403 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8f01de8608baf9f11758b6859136175c7d69c06d --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 1390, + "title": "Average number of proteins per term", + "value": 20.220143884892085 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f2b9029439eed98de6c0f2c6fcfa5e3d0a8ec56a --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d6722981b4b039963cebdcc131f7688429ba19ff --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,659 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +C type lectin receptors clrs 0.5585033891765643 4.281913962750278 1.8529262921340717e-05 0.0254270598881588 0.020106695671043 57 P62191,P60900,P43686,P62333,Q13177,P25789,Q15008,P25786,P20618,P25787,Q16512,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,O43318,P61289,P49427,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,Q8TBC4,Q14790,P28072,P25788,O00231,Q04206,Q13153,P28074,P17612,P62195,Q13200 42 +Fc epsilon receptor fceri signaling 0.5481567237454193 4.160944739902802 3.169337745045908e-05 0.0430981881853961 0.020106695671043 58 P62993,P62191,P60900,P43686,P62333,Q13177,P25789,Q15008,P25786,P20618,P25787,Q16512,O00487,O15111,Q13616,O14818,P19174,O43242,P28066,Q14997,P49427,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28482,Q04206,Q13153,P45985,P28074,P62195,Q13200 42 +Switching of origins to a post replicative state 0.5384273455364439 4.045148618319827 5.228994130157538e-05 0.0701062240535802 0.020106695671043 59 P62191,P33992,P60900,P43686,P62333,Q13200,P25789,P25205,Q15008,P25786,P33993,P20618,P25787,O00487,Q13309,Q13616,Q9H1A4,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,O00231,P51665,Q9UJX4,P20248,Q14566,Q99741,Q9UJX5,P28074,P62195,Q16763 44 +Antigen processing ubiquitination proteasome degradation 0.5711385543594419 3.891445404324387 9.964881335511322e-05 0.1293530755100922 0.0277023701127217 91 P62191,Q9Y3I1,Q5T4S7,P60900,Q15369,Q13200,Q92990,Q7Z6Z7,Q93034,Q15008,P25786,P22314,P25787,P20618,O00487,Q14999,Q13309,O14818,P68036,P28066,P49427,Q14997,P61081,P55036,O43242,P61289,P49720,Q8IWV7,P19474,Q13617,P28070,Q15386,P49721,Q9C0C9,Q9UII4,Q9ULT8,Q8TBC4,Q9Y4B6,P61086,Q9UJX4,P55786,Q05086,O95376,O95352,Q7Z7E8,A0AVT1,O94822,P28074,P52888,P62195,Q16763 51 +Mitotic g1 phase and g1 s transition 0.5386541091567133 3.778745454170086 0.0001576204405042 0.1967663860128914 0.028654025382573 76 P62191,P33992,P63151,P49643,P43686,P60900,P62333,P25789,P25205,Q15008,P42771,P25786,P33993,P20618,P25787,P31350,O00487,Q13309,P04818,Q13616,P35244,O14818,O43242,P28066,P11802,P55036,P49720,P61289,O75832,P27694,Q9UNM6,P49642,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,P31751,P51665,O00231,P00374,P20248,P04183,Q14566,Q99741,P30154,Q07864,Q00534,P28074,P14635,Q13200,P62195 55 +Apc c mediated degradation of cell cycle proteins 0.5375226119275319 3.735977872279374 0.0001869871117414 0.228899364854023 0.0288791205911837 55 P62191,P60900,P43686,P62333,P53350,P25789,Q13200,Q15008,P25786,P20618,P25787,O00487,Q13309,Q13616,Q9H1A4,O60566,O14818,O43242,P28066,Q14997,O43684,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,O14965,P25788,O00231,P51665,Q9UJX4,P20248,Q9UJX5,P28074,P14635,Q16763,P62195 41 +Signaling by hedgehog 0.4966370434514534 3.623117710927645 0.0002910732779217 0.332790207261093 0.0362016737461113 58 P68371,P62191,P43686,P60900,P62333,P25789,Q15008,Q9BUF5,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P49407,P48556,P28072,P25788,Q13618,O00231,P51665,P04350,Q9BVA1,P28074,Q13885,P17612,P62195,Q13200 38 +Dna replication pre initiation 0.4996450772383568 3.60556189237112 0.000311478241278 0.3514539043752103 0.0362016737461113 61 P62191,P33992,P49643,P60900,P43686,P62333,P25789,P25205,Q15008,P25786,P33993,P20618,P25787,O00487,P35244,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P27694,Q9UNM6,P49642,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,O00231,P51665,Q14566,Q99741,Q07864,P28074,P62195,Q13200 42 +Clec7a dectin 1 signaling 0.5519270790125194 3.58242336333768 0.0003404215021323 0.3770359381998652 0.036398914458763 53 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,O43318,P61289,P49427,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,Q8TBC4,Q14790,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 39 +Synthesis of dna 0.5247751354467735 3.541691608287942 0.0003975699915437 0.424624363373181 0.0394730205889839 82 P62191,P41440,P33992,P49643,P43686,P35251,P62333,P60900,P25789,P25205,Q15008,Q13200,P25786,P33993,P20618,P25787,P49005,O00487,Q13309,Q13616,Q9H1A4,Q9BRX5,P35244,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P27694,P39748,Q9UNM6,P28070,P18858,P49642,P28340,P49721,Q9UBD5,P33991,P49736,P48556,P28072,P25788,O00231,P51665,Q9UJX4,P20248,Q14566,Q99741,Q9UJX5,Q07864,P28074,P62195,Q9BRT9,Q16763 57 +Orc1 removal from chromatin 0.5738530697578836 3.521585451780029 0.000428974387022 0.4492103635582505 0.0397516265307102 51 P62191,P33992,P60900,P43686,P62333,P25789,P25205,Q15008,P25786,P33993,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P33991,Q9UBD5,P48556,P49736,P28072,P25788,O00231,P51665,P20248,Q14566,Q99741,P28074,P62195,Q13200 40 +Hedgehog off state 0.5543661634764009 3.4713468195065498 0.0005178546904125 0.513249917195468 0.0409544004856671 52 P68371,P62191,P60900,P43686,P62333,P25789,Q15008,Q9BUF5,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P04350,Q9BVA1,P28074,Q13885,P17612,P62195,Q13200 36 +Tcr signaling 0.553674532055347 3.4649425526550157 0.0005303447544906 0.5216318991753656 0.0409544004856671 52 P62191,P60900,P43686,P62333,Q13177,P25789,P41240,Q15008,P25786,P20618,P25787,Q16512,O00487,O15111,Q13616,O14818,P19174,O43242,P28066,Q14997,P49427,P55036,P49720,O43318,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,Q13153,P28074,P62195,Q13200 39 +Interleukin 1 signaling 0.572128196064007 3.272537007563001 0.0010658691791471 0.7728962446971837 0.0779767452112948 49 P62191,P60900,P43686,P62333,P25789,Q15008,P52564,Q02750,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,P09429,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P45985,P28074,Q13501,P62195,Q13200 39 +The role of gtse1 in g2 m progression after g2 checkpoint 0.5550793331097776 3.2341599697976604 0.0012200109974931 0.8167402228176889 0.0847907643257731 50 P68371,P62191,P43686,P60900,P62333,P53350,P25789,Q15008,O95067,Q9BUF5,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P08238,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P04350,Q9BVA1,P07900,P28074,Q13885,Q15691,P14635,Q13200,P62195 40 +Neddylation 0.479512727860883 3.176818958433708 0.0014889995501887 0.8739720793646308 0.0985575892743998 74 P62191,Q9Y3I1,P60900,P43686,Q15369,Q15008,Q93034,O60826,P25786,P20618,P25787,O00487,Q13309,Q14999,Q13619,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,P61289,Q86VP6,P61962,Q13617,Q9Y5A7,P28070,Q99627,P49721,Q5TAQ9,Q8TBC4,Q13618,P61201,Q13564,Q7L5N1,Q92905,P28074,P62195,Q13200 40 +Cilium assembly 0.4538154981766534 3.137214675607833 0.001705611931881 0.9067829580175676 0.1077636629688458 59 P68371,Q9UPT5,P53350,Q7Z460,Q96KP1,Q9BT25,P36405,Q9BUF5,P30153,Q3SYG4,Q14008,Q99996,Q15154,P78371,P61163,O43924,O94927,Q9BW83,P49368,Q92973,Q7Z4H7,P50991,P04350,P07437,Q14203,P17987,Q15019,Q9UIS9,Q92538,Q9BVA1,P43034,O75935,P07900,Q14204,Q8TAG9,Q13885,P17612,Q15691,P48643 39 +Mapk family signaling cascades 0.4901436318415333 3.092892506664071 0.0019821591836115 0.936577430982621 0.1197913593573939 87 P62191,Q9UQ13,P62993,P31946,P43686,P60900,P62333,Q13177,P25789,P60953,P41240,Q99956,Q15008,P46940,Q02750,P30153,P25786,Q92796,P25787,P20618,Q16512,O00487,O15020,O60725,Q16181,O14818,O14980,O43242,P28066,Q14997,P36507,P55036,P49720,Q96S59,P61289,O75832,Q9UNM6,O43924,O75608,P28070,P49721,P49407,P21359,Q9NZI8,Q13555,P48556,P28072,P25788,Q13618,O00231,P51665,Q15334,Q96P70,Q06124,P35998,Q9HCE1,P30086,P18206,P17980,Q9Y490,P28482,Q13153,P36404,Q99460,P30154,Q14738,P28074,P17612,P62195,Q13200,Q9Y4G8 71 +Transcriptional regulation by runx2 0.5170990162956257 3.000725713308664 0.0026933705582252 0.9764548599539424 0.155991044830547 51 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P11802,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,P31751,P51665,O00231,P28482,P28074,P14635,Q13200,P62195 35 +Eukaryotic translation elongation 0.4658850988433671 2.962600627815018 0.0030505208056206 0.9856886814577396 0.1696089567925069 78 Q05639,P84098,P46776,P62861,P62750,P60866,P62906,P62917,P61254,P61247,P50914,P46778,P36578,P29692,P62081,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P39019,P62269,P61513,P47914,P83731,P13639,P05387,P62753,P18621,P62899,P15880,P39023,P62266,P46783,P62841,P26641 38 +Degradation of beta catenin by the destruction complex 0.5403869745157147 2.8912157712981004 0.0038375454338512 0.9952254211526124 0.2051610828097418 48 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P30154,Q14738,P28074,P62195,Q13200,Q04727 33 +Dna replication 0.4718828107655989 2.8757568529674904 0.0040306006374 0.9963530209347892 0.2075012920735565 88 P62191,P41440,P33992,P49643,P43686,P35251,P62333,P60900,P25789,P25205,Q15008,Q13200,P25786,P33993,P20618,P25787,P49005,O00487,Q13309,Q13616,Q9H1A4,Q9BRX5,P35244,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P27694,P39748,Q9UNM6,P28070,P18858,P49642,P28340,P49721,Q9UBD5,P33991,P49736,P48556,P28072,P25788,O00231,P51665,Q9UJX4,P20248,Q14566,Q99741,Q9UJX5,Q07864,P28074,P62195,Q9BRT9,Q16763 57 +Dectin 1 mediated noncanonical nf kb signaling 0.585440187328728 2.82795006532751 0.0046847113208785 0.9985366828096522 0.2177464383648266 43 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,Q8TBC4,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 35 +Response of eif2ak4 gcn2 to amino acid deficiency 0.4530193962124682 2.817982862555222 0.0048326389150989 0.9988098213806736 0.2177464383648266 78 P46776,P84098,P62750,P62861,P60866,P62917,P62906,P61254,P61247,P50914,P46778,P36578,P62081,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P08243,P39019,P62269,P61513,P47914,P83731,P05387,P62753,Q92616,P18621,P62899,P15880,P05198,P39023,P62266,P46783,P62841 37 +Fceri mediated nf kb activation 0.5534727470016186 2.8164198696027043 0.0048562155318774 0.998848376867487 0.2177464383648266 46 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,O14818,O43242,P28066,Q14997,P49427,P55036,P49720,O43318,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 34 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5412516701888259 2.802992419249647 0.0050630859411768 0.9991374056618536 0.2199277955698708 47 P62191,P60900,P43686,P62333,P53350,P25789,Q13200,Q15008,P25786,P20618,P25787,O00487,Q13309,Q9H1A4,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,O14965,P25788,O00231,P51665,Q9UJX4,Q9UJX5,P28074,P62195,Q16763 36 +Signaling by the b cell receptor bcr 0.493992215435697 2.781122759267146 0.0054171248577632 0.9994740331923132 0.227779932483865 51 P62993,P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,O00221,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 36 +Tnfr2 non canonical nf kb pathway 0.5771682628136167 2.762700649807997 0.0057325314977212 0.9996615538204164 0.227779932483865 43 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P61081,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,Q8TBC4,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 34 +Mismatch repair 0.751404159934222 2.7530489951987356 0.0059043059274088 0.9997338124191756 0.227779932483865 12 P28340,P35244,P49005,P20585,Q9UQ84,P18858 6 +S phase 0.4686752358281195 2.7503614432163133 0.0059529561231965 0.9997513181989768 0.227779932483865 94 P62191,P41440,P33992,P49643,P43686,P35251,P62333,P60900,P25789,P25205,Q15008,Q13200,P25786,P25787,P20618,P49005,P33993,O00487,Q13309,Q13616,Q9H1A4,Q9BRX5,P35244,O14818,O43242,P28066,Q14997,P11802,P55036,P49720,P61289,O75832,P27694,P39748,Q9UNM6,P28070,P18858,P49642,P28340,P49721,Q9UBD5,P33991,P49736,P48556,P28072,P25788,O00231,P31751,P51665,Q9UJX4,P20248,Q29RF7,Q14566,Q7Z5K2,Q99741,Q9UJX5,Q07864,P28074,P62195,Q9BRT9,Q16763 61 +Regulation of hmox1 expression and activity 0.5549852670922066 2.7429162202271864 0.0060896220178092 0.9997945797643204 0.227779932483865 45 P62191,P60900,P43686,P62333,P25789,Q15008,P68400,P25786,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,P28070,P49721,P19784,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 35 +Selenoamino acid metabolism 0.4631814243146335 2.7331887916141917 0.0062724367715647 0.9998409267390268 0.227779932483865 91 P46776,P84098,P62750,P62861,Q9P2J5,P60866,P62906,O43252,P61254,P61247,P62917,P00390,P62263,P50914,P56192,P46778,P36578,Q02543,P26373,Q13155,P62829,P54136,P62081,P61313,P32969,P62701,P27635,P62847,P08708,P62854,P07814,P47897,P42766,P62241,P41252,P39019,P62269,P61513,P47914,P23526,P83731,P14868,P49591,P32929,P05387,P62753,P18621,P62899,P15880,P62851,P62280,P39023,P62266,P46783,P62841 55 +Nucleotide salvage 0.7465063222344065 2.7154435402839447 0.0066187060888507 0.9999020038660048 0.227779932483865 10 Q08623,Q9P2T1,P00813,Q9BZX2,P00492,Q01433,P07741,P04183 8 +Mitotic g2 g2 m phases 0.463808704271359 2.710475131851846 0.0067186886559988 0.9999147984819544 0.227779932483865 93 P68371,P62191,P63151,P43686,P60900,P53350,Q7Z460,P25789,Q15008,O95067,Q9BT25,Q9BUF5,P25786,P20618,P25787,O00487,Q14008,Q99996,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,Q96CW5,P61289,P08238,P28070,P49721,Q7Z4H7,O14965,Q9Y570,P04350,Q9BSJ2,Q14203,P07437,P20248,P30307,Q9UIS9,P43034,O75935,P07900,P30154,P14635,P28074,Q13885,Q14204,Q15691,P62195,Q13200 51 +Regulation of pten stability and activity 0.5781209067718542 2.696087309438939 0.0070159274499741 0.9999437952993556 0.2282875924706829 42 P62191,P60900,P43686,P62333,P25789,Q15008,P68400,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,P28070,P49721,P19784,P48556,P28072,P25788,P31751,P51665,O00231,P28074,P62195,Q13200 33 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.7422473953829922 2.693900037220488 0.0070621341555678 0.9999473156856412 0.2282875924706829 10 Q96BN8,P68036,P49427,P61086,Q93008,P45974,P22314,Q16763 8 +Tcf dependent signaling in response to wnt 0.421316811842977 2.6825070740616415 0.0073072606350672 0.999962620357598 0.2308430064259884 64 P62191,P60900,P43686,Q15008,P25786,P20618,P25787,O00487,Q9HCK8,P63104,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P61289,P67870,P28070,P49721,P19784,P40818,Q13618,P31751,P30154,Q14738,P28074,P62195,Q13200,Q04727 31 +Interleukin 1 family signaling 0.4581481233077172 2.6583300441166924 0.007852894737709 0.9999825924863136 0.2395316771643153 53 P62191,P60900,P43686,P62333,P25789,Q15008,P52564,Q02750,P25786,P20618,P25787,O00487,O15111,Q13616,Q00653,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,P09429,Q9UNM6,P40763,P28070,P49721,P48556,P28072,P25788,O00231,Q06124,Q04206,P45985,Q9UHD2,P28074,Q13501,P62195,Q13200 41 +Cellular response to hypoxia 0.5773817504563711 2.620672289152346 0.0087756574819706 0.9999952244555296 0.2571437388745793 41 P62191,P60900,P43686,P62333,Q15369,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,Q13617,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q9GZT9,P28074,P62195,Q13200 32 +Regulation of runx2 expression and activity 0.5649153554989693 2.592643949302984 0.0095241314672005 0.999998328833574 0.2593598599766946 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,Q13309,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 31 +Scf skp2 mediated degradation of p27 p21 0.5814800943051501 2.5862493517843084 0.0097026710207108 0.9999986992474966 0.2593598599766946 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,Q13309,O00487,Q13616,O14818,O43242,P28066,P11802,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P20248,P28074,P62195,Q13200 32 +Cyclin a cdk2 associated events at s phase entry 0.5630441253893597 2.577907077832045 0.0099400723878657 0.999999067902668 0.2606924645119511 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13309,Q13616,O14818,O43242,P28066,P11802,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,P31751,P51665,O00231,P20248,P28074,P62195,Q13200 33 +Downstream signaling events of b cell receptor bcr 0.5044685199925066 2.5713289313177814 0.0101309052849849 0.9999992869934986 0.2607770064097978 48 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,Q13616,O00221,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q04206,P28074,P62195,Q13200 35 +Mapk6 mapk4 signaling 0.492083123367487 2.5535686513754356 0.0106625256710597 0.9999996620916202 0.2694711033231463 49 P62191,P60900,P43686,P62333,Q13177,P25789,P60953,Q15008,P25786,P20618,P25787,Q16512,O00487,Q16181,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,Q9NZI8,P48556,P28072,P25788,O00231,P51665,P35998,Q9HCE1,P17980,Q13153,Q99460,P28074,P17612,P62195,Q13200 41 +Ub specific processing proteases 0.4257560286202986 2.537699568071883 0.0111583728081865 0.9999998316669384 0.2769667536317732 76 P62191,P60900,P43686,P62333,Q96K76,P25789,Q15008,Q14694,P25786,P51784,P20618,P25787,Q13546,O00487,Q13309,Q93009,Q92890,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,P45974,O75832,Q96FW1,Q9UNM6,Q96RU2,P28070,P49721,P40818,P49407,Q9UPT9,P48556,P28072,P25788,O00231,P20248,O60493,P14735,Q16186,Q86UV5,Q9NZL9,Q9Y4A5,O94966,Q93008,P28074,P62195,Q13200 51 +Regulation of ras by gaps 0.5891058379160476 2.5221522845292546 0.0116639201321273 0.9999999173080352 0.2844359470817023 38 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P21359,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 31 +Hedgehog on state 0.5545281036847346 2.5105935363857848 0.0120528386524036 0.9999999521515772 0.2888525125317437 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P49407,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 31 +Degradation of gli1 by the proteasome 0.5705697312142368 2.503381906752321 0.0123012725018096 0.9999999662676188 0.2897748241185642 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P17612,P62195,Q13200 31 +Cdt1 association with the cdc6 orc origin complex 0.5614555055051735 2.497471106958311 0.0125082657892905 0.999999974792952 0.2897748241185642 41 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,Q9UBD5,P48556,P28072,P25788,O00231,P51665,Q99741,P28074,P62195,Q13200 31 +Degradation of dvl 0.5868089774540616 2.4501568579768227 0.0142793993716767 0.9999999979211276 0.2971432407528053 37 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,Q13618,O00231,P51665,P28074,P62195,Q13200 30 +Processive synthesis on the lagging strand 0.6913409824169426 2.440206046258215 0.0146788868529534 0.999999998816614 0.2971432407528053 12 P28340,P49005,P35244,P18858 4 +Negative regulation of notch4 signaling 0.5685457019627743 2.427316659642882 0.0152109728229468 0.9999999994414664 0.2971432407528053 39 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,P63104,O14818,O43242,P28066,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30 +Metabolism of polyamines 0.5757983447875521 2.4241665342796863 0.0153435675151196 0.9999999995368049 0.2971432407528053 38 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P19623,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30 +Cross presentation of soluble exogenous antigens endosomes 0.585610256367509 2.389823360727892 0.0168564777842696 0.9999999999453586 0.3119556943084979 36 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29 +Degradation of axin 0.585610256367509 2.389823360727892 0.0168564777842696 0.9999999999453586 0.3119556943084979 36 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29 +Regulation of runx3 expression and activity 0.5852057532216548 2.386926227892392 0.0169899001879514 0.9999999999547527 0.3119556943084979 36 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,P25787,O00487,O14818,O43242,P28066,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29 +Negative regulation of mapk pathway 0.6814483694213007 2.383234054625861 0.0171612793108202 0.999999999964491 0.3119556943084979 11 P31946,P36507,Q99956,Q14738,P28482,P30086 6 +Asymmetric localization of pcp proteins 0.5709903200994053 2.334927692114681 0.0195471984311863 0.9999999999987892 0.3313488514554759 37 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29 +Processive synthesis on the c strand of the telomere 0.669812761701425 2.325348467226142 0.0200533346328457 0.9999999999994093 0.3325713676879427 12 P49005,P35244,P18858 3 +Eukaryotic translation initiation 0.4406742355235936 2.316011925355243 0.0205576175744828 0.9999999999997112 0.3325713676879427 102 P49770,P46776,P84098,P62750,P62861,P60866,P62917,P62906,P61254,P61247,P50914,Q15056,Q14232,P46778,Q14152,P62081,P32969,O60841,P62701,P27635,P62847,P08708,P62854,P42766,P39019,P62269,O15371,P61513,P47914,P83731,P55010,Q13144,Q9Y262,Q04637,P05387,P62753,Q14240,P18621,P62899,P15880,P05198,Q9NR50,P06730,P39023,P62266,P46783,O75821,P62841 48 +G1 s dna damage checkpoints 0.5365310196595392 2.301972137622654 0.0213367434972435 0.9999999999999044 0.3325713676879427 41 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,O96017,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P20248,P28074,P62195,Q13200 32 +Regulation of expression of slits and robos 0.4641234309493209 2.2939846420050536 0.0217913809239238 0.99999999999995 0.3325713676879427 123 P84098,P62861,Q15369,P62333,P61254,P61247,P62906,P50914,P46778,P36578,P25787,O00487,P27635,P28066,P62847,P62241,Q13617,P28070,O00231,P18621,P46776,Q02543,P25786,P62829,P20618,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P39019,Q9UNM6,P11940,P48556,P28072,P25788,P15170,P51665,P05387,P62899,P15880,P62851,P62280,Q99460,P39023,P62266,P46783,P62841,P62195,Q9BZI7,P62191,P62263,P26373,P61313,O14818,O43242,P62854,P61289,P62269,P61513,P49721,P47914,Q04637,P28074,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P49720,O75832,Q9HAU5,P83731,P62753,Q13200 80 +Condensation of prometaphase chromosomes 0.6644968741308603 2.2930974895377005 0.0218423928951678 0.9999999999999534 0.3325713676879427 11 O95067,Q15021,Q15003,P67870,Q9NTJ3,P14635,Q9BPX3,P19784 8 +Cyclin a b1 b2 associated events during g2 m transition 0.6622322533264839 2.2845640474617235 0.0223384030747419 0.999999999999977 0.3325713676879427 12 P63151,O14980,P30154,Q9Y570,O95067,P20248,P30307,P14635 8 +Gap filling dna repair synthesis and ligation in gg ner 0.6522251899170336 2.281028085876651 0.0225467849760012 0.9999999999999828 0.3325713676879427 18 P28340,P35244,Q07864,P49005,P18858 5 +Beta catenin independent wnt signaling 0.3779097015970279 2.271452564762543 0.0231195954202951 0.9999999999999925 0.3325713676879427 58 O94973,P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,O75832,Q9UNM6,Q08209,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q9HCE1,Q00610,P28074,P07737,P62195,P09471,Q13200 36 +Regulation of mrna stability by proteins that bind au rich elements 0.3834785356105973 2.269989539264924 0.0232082177451298 0.9999999999999932 0.3325713676879427 62 P62191,P31946,P60900,P43686,P25789,Q15008,Q16539,P25786,P20618,P25787,O00487,P63104,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P28070,P49721,Q01105,Q92973,Q04637,Q9Y2L1,P28074,P62195,Q13200 30 +Post chaperonin tubulin folding pathway 0.6583202177414264 2.2600356646174857 0.0238190374423132 0.9999999999999972 0.3373515876591558 11 P68371,Q99426,P36404,P04350,Q15813,Q9BUF5,Q13885,Q9BTW9,O75347 9 +Cytoprotection by hmox1 0.3878705518658862 2.255322378817858 0.0241131009401294 0.999999999999998 0.3373515876591558 66 O75182,P62191,O75880,P43686,P60900,P62333,P53004,P25789,Q5RI15,Q15008,P68400,P25786,P20618,P25787,Q86X55,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,Q15648,P40763,P28070,P49721,P19784,P30043,P48556,P28072,P25788,Q13618,O00231,P14854,P30519,P28074,P62195,Q13200 44 +Nonsense mediated decay nmd 0.4142621860287027 2.23222881686896 0.0255998437659881 0.9999999999999998 0.3378708709135505 87 P46776,P84098,P62750,P62861,P60866,P63151,P62906,P62917,P61254,P61247,P62263,P50914,Q92900,P46778,P36578,Q02543,P30153,P26373,P62829,P62081,P32969,P62701,P27635,P62847,P08708,P62495,P62854,P42766,P62241,P39019,P62269,P61513,Q9UPR3,Q9HAU5,P47914,P11940,P83731,P15170,Q04637,P05387,P62753,P18621,P62899,P15880,P62851,P62280,P39023,P62266,P46783,P62841,Q9BZI7 51 +Purine ribonucleoside monophosphate biosynthesis 0.6521349816301546 2.225076818995401 0.0260760816234768 1.0 0.3378708709135505 10 Q06203,P30520,P49915,P20839,P30566,P31939,O15067 7 +Interleukin 6 family signaling 0.8519600690909137 2.217942427543054 0.0265587581565833 1.0 0.3378708709135505 4 P40763,P22681 2 +Interleukin 6 signaling 0.8519600690909137 2.217942427543054 0.0265587581565833 1.0 0.3378708709135505 4 P40763,P22681 2 +Stabilization of p53 0.5329209684477143 2.2127936050136645 0.026911878379092 1.0 0.3378708709135505 40 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,O96017,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 31 +Cyclin d associated events in g1 0.6746452518051098 2.183420845395713 0.0290048322290508 1.0 0.3402152650391918 9 P63151,P11802,P42771,Q00534,Q13309 5 +Signaling by notch4 0.5127306698037238 2.174550876776673 0.0296637888981525 1.0 0.3402152650391918 42 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,Q13616,P63104,O14818,O43242,P28066,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30 +Synthesis of pc 0.7609531583901743 2.170668321721831 0.0299562534543122 1.0 0.3402152650391918 6 Q9NQZ5,P35790,P67870 3 +Hdr through homologous recombination hrr 0.611221148942977 2.165502000402276 0.0303492623711116 1.0 0.3402152650391918 25 P28340,P41440,P35244,P49005,Q07864,O60921,Q9UQ84,Q13535 8 +Purine salvage 0.7295263202474483 2.1607337560939457 0.0307159117797584 1.0 0.3402152650391918 7 Q9P2T1,P00813,P00492,Q01433,P07741 5 +Vitamin b5 pantothenate metabolism 0.7580755600817861 2.1577037821442984 0.0309508697158578 1.0 0.3402152650391918 6 Q13057,Q9NVE7,P49327 3 +Pten regulation 0.381105731908133 2.1411905433754583 0.0322586753367999 1.0 0.3427217888915995 68 P62191,P60900,P43686,P62333,P25789,Q15008,P68400,Q12873,P25786,P20618,P25787,O00487,Q93009,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q15382,P67870,Q9UNM6,P28070,P49721,P19784,P48556,P28072,P25788,P31751,O00231,Q9HCE1,P28482,P28074,P62195,Q13200 37 +Netrin 1 signaling 0.6343331451376801 2.1329556617440844 0.0329283635643662 1.0 0.3427217888915995 12 O00401,Q13153,P19174,Q16539,Q14185,Q00169,Q06124,Q16512,P15311 9 +G2 m checkpoints 0.4069707040133414 2.131604582782838 0.0330393666989023 1.0 0.3427217888915995 88 P62191,P33992,P31946,P43686,P60900,P62333,P25789,P25205,Q15008,O95067,Q92547,P25786,P20618,P25787,O96017,Q9UQ84,O00487,Q9NXR7,P35244,P27348,P63104,O14818,O43242,P28066,Q14997,P55036,P49720,O60921,P61289,O75832,P27694,P28070,P49721,Q9UBD5,P33991,P49736,P30307,Q13535,Q99741,P14635,P28074,P62195,Q13200 43 +Pcna dependent long patch base excision repair 0.6248563074301915 2.123903811400572 0.0336781876310787 1.0 0.3438053293307518 18 P28340,P41440,P35244,Q07864,P49005,P18858 6 +Caspase mediated cleavage of cytoskeletal proteins 0.6607941607593035 2.1123167073159297 0.0346592937786645 1.0 0.3438053293307518 9 P55212,P42574,P55210,Q14790 4 +Hedgehog ligand biogenesis 0.5246258184486242 2.092000292978342 0.0364384894899858 1.0 0.3438053293307518 39 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29 +Flt3 signaling 0.7819477150686335 2.090235268223638 0.0365966708611735 1.0 0.3438053293307518 5 P22681,P31751,Q06124 3 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.5169801728137617 2.0877071989200338 0.0368242550669233 1.0 0.3438053293307518 40 P62191,Q03164,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P28070,P49721,P28074,P62195,Q13200 22 +Activation of atr in response to replication stress 0.6073992991412288 2.079718356469509 0.0375513733885886 1.0 0.3438053293307518 22 Q9UBD5,O60921,P25205,P35244 4 +Maturation of sars cov 2 nucleoprotein 0.7358998733355995 2.0571991691368128 0.0396670714445177 1.0 0.3534437776146133 6 P78362,Q99873 2 +Signaling by notch 0.357763658801837 2.0440438701890864 0.040949213409072 1.0 0.3579836895510076 57 P62191,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,P63104,O14818,O43242,P28066,P55036,P49720,P61289,P28070,P49721,P49407,Q9HCE1,P28074,P67809,Q15398,P62195,Q13200,Q04727 26 +Signaling by robo receptors 0.4576301650692044 2.041017357016328 0.0412491018890048 1.0 0.3583515726607298 137 P84098,P62861,Q15369,P62333,P61254,P61247,P60953,Q7Z460,P62906,P50914,P46778,P36578,P25787,O00487,P27635,P28066,P62847,P62241,Q13617,P28070,O00231,P18621,P46776,Q13177,Q02543,P25786,P62829,P20618,Q16512,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P39019,Q9UNM6,P11940,P48556,P28072,P25788,P15170,P51665,P05387,P62899,P15880,P62851,P62280,Q99460,P39023,P62266,P46783,P62841,P62195,Q9BZI7,P62191,P62263,P26373,P61313,O14818,O43242,P62854,P61289,P62269,P61513,P49721,P47914,Q04637,Q13153,P28074,P07737,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P49720,O75832,Q9HAU5,P83731,P62753,P35080,P17612,Q13200 88 +Uch proteinases 0.4639776702616915 2.0374751779433606 0.0416024469194695 1.0 0.3591764050811348 46 P62191,P60900,P43686,P25789,Q15008,P85037,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P28070,P49721,Q9Y5K5,Q16186,P28074,P62195,Q13200 24 +Constitutive signaling by akt1 e17k in cancer 0.7257019775677501 2.0106314970760772 0.0443643945884142 1.0 0.3594469004391438 6 P31751 1 +Recycling of eif2 gdp 0.6959437820157307 2.00176906305558 0.0453095746876823 1.0 0.3594469004391438 7 P49770,P05198,Q14232,Q13144 4 +Copi mediated anterograde transport 0.3539012980445294 1.996717331075939 0.0458558983473313 1.0 0.3594469004391438 57 P47756,P68371,P53621,Q8N6T3,P54920,Q9BUF5,Q9UBF2,P47755,Q9Y6G9,O15020,P61923,Q14789,P61163,P04350,Q96JB2,Q14203,O43237,P24390,P53618,P48444,Q9NZ32,Q9BVA1,Q92538,Q9Y678,O75935,Q14746,Q13885,Q14204,P35606 29 +Transcriptional regulation by runx3 0.4979655775413396 1.9934480644099355 0.0462124052017969 1.0 0.3594469004391438 41 P62191,P60900,P43686,P62333,P25789,Q15008,P42771,P25786,P20618,P25787,O00487,O14818,O43242,P28066,P55036,P49720,P61289,P25440,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 30 +Raf independent mapk1 3 activation 0.6864307229864066 1.9562793419100877 0.0504322563637886 1.0 0.3602482725675702 7 P36507,Q99956,Q06124 3 +Inositol phosphate metabolism 0.6560182063707389 1.9427381892758455 0.0520477995239427 1.0 0.3653860673650528 8 Q13572,Q96PE3,O15357,P19174,Q01968 5 +Cytosolic iron sulfur cluster assembly 0.655057173696743 1.937924902612031 0.0526323852817605 1.0 0.3657950777082355 8 P28340,Q96T76,P18074,Q9Y5Y2 4 +Formation of tubulin folding intermediates by cct tric 0.597469173853617 1.9350097753334103 0.0529890961300263 1.0 0.3658459437762534 14 P68371,P49368,Q99832,P50991,P04350,P40227,Q9BUF5,Q13885,P17987,P48643 10 +Fanconi anemia pathway 0.6815552808531826 1.932889808101981 0.0532497736721506 1.0 0.3658459437762534 7 P35244 1 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.3987058247686542 1.9280757072560777 0.0538457101068479 1.0 0.3668898874927382 52 P60866,P62861,Q15056,Q14152,P62081,P62701,P62847,P08708,P62854,P39019,P62269,Q9Y262,Q04637,P62753,Q14240,P15880,P05198,P62266,P46783,O75821,P62841 21 +Class i mhc mediated antigen processing presentation 0.4243354565652015 1.9194038055238765 0.0549332497075958 1.0 0.3704869385433925 117 P62191,Q9Y3I1,Q5T4S7,P60900,Q15369,Q13200,Q92990,Q7Z6Z7,Q93034,Q15008,P25786,P22314,P25787,P20618,O00487,Q14999,O15111,Q13309,O14818,Q9Y6B6,P68036,P28066,P49427,Q14997,P61081,P55036,O43242,P61289,P49720,P09429,Q8IWV7,P19474,Q13617,P28070,Q15386,P49721,Q9C0C9,Q9UII4,Q9ULT8,Q8TBC4,Q9Y4B6,P61086,Q9UJX4,P55786,Q05086,O95376,O95487,O95352,P60059,Q7Z7E8,A0AVT1,O94822,P28074,P52888,P62195,Q16763 56 +Lagging strand synthesis 0.5896840941938118 1.918655093417016 0.0550279982287209 1.0 0.3704869385433925 18 P28340,P41440,P35244,P49005,P18858 5 +Nucleotide biosynthesis 0.5945630123042086 1.9150074945268576 0.0554915478406599 1.0 0.3704869385433925 13 P11172,P30520,Q06203,P49915,P20839,P27708,P30566,P31939,O15067 9 +Costimulation by the cd28 family 0.5932807137097386 1.911241105422844 0.0559736036769018 1.0 0.3704869385433925 14 P62993,Q13153,Q13177,P30154,P60953,P41240,P31751,Q14738,P30153,Q06124,Q16512 11 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5897796101785223 1.909970787367685 0.0561369747065536 1.0 0.3704869385433925 17 P68371,P49368,Q99832,Q9BVA1,P50991,P04350,P40227,Q9BUF5,Q99471,Q13885,P17987,P48643 12 +G2 m dna replication checkpoint 0.7791883552049762 1.909176054543303 0.0562393841961552 1.0 0.3704869385433925 4 O95067 1 +Akt phosphorylates targets in the cytosol 0.7391489896645984 1.900969276414334 0.0573060369837954 1.0 0.3757329783371493 5 P31751 1 +Interleukin 3 interleukin 5 and gm csf signaling 0.6468057035497534 1.8965110190443013 0.057892504320743 1.0 0.3769926732618025 8 P62993,P63104,O15357,P46109,Q06124,P22681 6 +Activation of the pre replicative complex 0.5815190336006327 1.8929217315009756 0.0583682788063062 1.0 0.3769926732618025 20 Q9UBD5,P25205,P35244,Q07864 4 +Nuclear events kinase and transcription factor activation 0.5887066083283478 1.8819794662170688 0.0598388036732795 1.0 0.3769926732618025 13 Q8IV63,Q00535,P50570,P30154,Q16539,Q14738,P28482 7 +Dual incision in gg ner 0.5692916954932647 1.8815503728815532 0.0598970897661814 1.0 0.3769926732618025 24 P28340,P41440,P35244,Q92759,Q07864,P18074,P49005 7 +Flt3 signaling in disease 0.6967245370185945 1.877152061012656 0.0604972557580334 1.0 0.3769926732618025 6 P22681,P62993,Q92614,Q06124 4 +Intracellular signaling by second messengers 0.3878321648531319 1.8757498335232012 0.0606896395109268 1.0 0.3769926732618025 90 P62191,P62993,O43815,P43686,P62333,P60900,P25789,Q15008,P68400,Q12873,P25786,P20618,P25787,O00487,Q93009,O15111,O14818,P19174,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q15382,P67870,Q9UNM6,P28070,P49721,P19784,Q13555,P48556,P28072,P25788,O00231,P31751,Q8TBX8,Q06124,Q9HCE1,P28482,Q96B36,P30154,Q14738,P28074,P17612,P62195,Q13200 48 +Cellular response to starvation 0.3915070250514548 1.874628614431511 0.0608438337828465 1.0 0.3769926732618025 93 P46776,P84098,P62750,P62861,P36543,P60866,P62906,P62917,P61254,P61247,Q9Y5K8,P50914,P46778,P62081,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P08243,Q15382,P39019,P62269,P61513,P47914,P83731,P05387,P62753,Q92616,P18621,P62899,P15880,P05198,P39023,P62266,P46783,P62841 39 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.7331939049895424 1.874372123715411 0.060879152932743 1.0 0.3769926732618025 5 Q99570,P31751,O14654,Q06124 4 +Regulation of localization of foxo transcription factors 0.6689337560388708 1.8721053619902317 0.0611920283332541 1.0 0.3769926732618025 7 P31946,P31751,P27348 3 +Signaling by pdgf 0.6951850058236626 1.870014115677947 0.0614818576882736 1.0 0.3769926732618025 6 P46109,P19174,P40763,Q06124 4 +Downstream signal transduction 0.6951850058236626 1.870014115677947 0.0614818576882736 1.0 0.3769926732618025 6 P46109,P19174,P40763,Q06124 4 +Assembly and cell surface presentation of nmda receptors 0.5864670501648593 1.867184414853828 0.0618758392619049 1.0 0.3769926732618025 11 P68371,Q13555,P04350,Q15334,Q9BUF5,Q13885,Q92796 7 +Map2k and mapk activation 0.5861555425342573 1.86545010990175 0.0621183390665427 1.0 0.3769926732618025 11 P31946,P41240,P36507,P46940,Q9Y490,P28482,P30086,P49407 8 +Ctla4 inhibitory signaling 0.6937990761142458 1.863584452836745 0.0623800826260536 1.0 0.3769926732618025 6 P31751,Q06124,Q14738 3 +Regulation of tp53 activity 0.3455161451740421 1.859391025820436 0.0629717329160595 1.0 0.3789208171139511 59 P35244,O14965,P31751,P42771,O14744,Q92547,Q9UER7,O60921,P20248,P67870,Q9UQ84,Q13535,P19784 13 +Insulin receptor signalling cascade 0.688141250296274 1.8372986404733715 0.0661658204956947 1.0 0.3839585743010401 6 P28482,P31751,Q06124 3 +Cytosolic trna aminoacylation 0.5643953341707764 1.832776963012157 0.0668357464035032 1.0 0.3839585743010401 23 Q9P2J5,P26639,O43776,P14868,P49591,P26640,P07814,P41250,P47897,P49589,Q9Y285,P41252,Q13155,P23381,P54136,P54577,Q15181,Q9NSD9 18 +Fceri mediated mapk activation 0.6066874790766914 1.8297673671511556 0.0672847324217849 1.0 0.3839585743010401 9 P45985,Q13153,P19174,P28482,Q16512 5 +Pcp ce pathway 0.4159363610206154 1.827595120836917 0.0676103386105224 1.0 0.3839585743010401 49 O94973,P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,Q00610,P28074,P07737,P62195,Q13200 32 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5245365744530586 1.8252893469325728 0.0679573769274561 1.0 0.3839585743010401 33 P47756,P68371,P54652,Q9BUF5,P47755,Q9Y6G9,P08238,P61163,P31689,P0DMV9,P04350,Q14203,P11142,P31948,O43237,Q15185,Q9NZ32,Q9BVA1,O75935,P07900,Q9UJW0,O60884,Q13885,Q14204 24 +Dna replication initiation 0.7221017426915717 1.8246697774309864 0.0680508766405734 1.0 0.3839585743010401 5 P49642,Q07864 2 +Homologous dna pairing and strand exchange 0.5745213552182578 1.820654679113016 0.0686593654499108 1.0 0.3839585743010401 17 O60921,Q9UQ84,P35244 3 +Hdr through single strand annealing ssa 0.5745213552182578 1.820654679113016 0.0686593654499108 1.0 0.3839585743010401 17 O60921,Q9UQ84,P35244 3 +Synthesis of pips at the early endosome membrane 0.6839374838275875 1.817729479505377 0.0691054897260725 1.0 0.3839585743010401 6 Q13614,Q08AM6,Q96PE3 3 +Mapk targets nuclear events mediated by map kinases 0.5772606658633275 1.8171567156689228 0.0691931205187996 1.0 0.3839585743010401 10 Q8IV63,P30154,Q16539,Q14738,P28482 5 +Erk mapk targets 0.5772606658633275 1.8171567156689228 0.0691931205187996 1.0 0.3839585743010401 10 Q8IV63,P30154,Q16539,Q14738,P28482 5 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.5761711477314019 1.8096849969097133 0.0703446504469642 1.0 0.3839585743010401 12 P31946,P27348,P30307,O96017,P14635 5 +Recognition of dna damage by pcna containing replication complex 0.5696402060614261 1.8001673196169037 0.0718342223835915 1.0 0.3840368042815084 18 P28340,P49005,P35244,Q07864 4 +Auf1 hnrnp d0 binds and destabilizes mrna 0.4732499654476684 1.7924434289595836 0.0730619633791607 1.0 0.3850004883250387 41 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P11940,P48556,P28072,P25788,O00231,P51665,Q04637,P28074,P62195,Q13200 31 +Abc transporter disorders 0.4792603978895989 1.7875805337287147 0.0738437084089382 1.0 0.3850004883250387 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29 +Defective cftr causes cystic fibrosis 0.4792603978895988 1.7875805337287147 0.0738437084089382 1.0 0.3850004883250387 40 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 29 +Carboxyterminal post translational modifications of tubulin 0.6501726545150441 1.7811544644196342 0.0748872202193644 1.0 0.3850004883250387 7 P68371,Q14166,P04350,Q9BUF5,Q13885 5 +Signaling by fgfr3 0.6500995533770669 1.7807987383552586 0.0749453356248879 1.0 0.3850004883250387 7 P22681,P19174,Q06124 3 +Signaling by fgfr4 0.6500995533770669 1.7807987383552586 0.0749453356248879 1.0 0.3850004883250387 7 P22681,P19174,Q06124 3 +Signaling by fgfr1 0.6500995533770669 1.7807987383552586 0.0749453356248879 1.0 0.3850004883250387 7 P22681,P19174,Q06124 3 +Signaling by scf kit 0.6490953686842809 1.7759111330588355 0.0757475656726067 1.0 0.3870923392828066 7 P40763,P22681 2 +Myd88 independent tlr4 cascade 0.5363224939271697 1.756171823439036 0.0790590742693981 1.0 0.3981598305596502 28 Q00653,Q8IV63,Q04206,Q14790,P45985,P30154,Q9UHD2,P52564,Q16539,Q14738,O43318,P09429,P51452,Q06124,P28482,Q13546,O15111 17 +Resolution of abasic sites ap sites 0.5487190580795774 1.7516303015851846 0.0798373986726417 1.0 0.3987828822695703 24 P28340,P41440,P35244,Q07864,P29372,P49005,P18858 7 +Recruitment of mitotic centrosome proteins and complexes 0.5172721835365641 1.7398960510570332 0.0818772722258407 1.0 0.4035978553183184 32 P68371,P53350,Q7Z460,Q9BT25,Q14008,Q99996,Q96CW5,P61163,Q7Z4H7,P04350,Q9BSJ2,P07437,Q14203,P17612,Q9UIS9,P43034,O75935,P07900,Q14204,Q15691 20 +Uptake and actions of bacterial toxins 0.563022344415254 1.7379051317174277 0.0822275313162612 1.0 0.4035978553183184 10 P45985,Q8WUM4,P07900,P36507,P52564,Q02750,P08238,P13639 8 +Signaling by ntrk2 trkb 0.7025380553036098 1.736519294125786 0.082472055855193 1.0 0.4035978553183184 5 P19174,Q00535,Q06124 3 +Termination of translesion dna synthesis 0.5586563949419507 1.7348245240089784 0.0827718909940804 1.0 0.4035978553183184 18 P28340,P41440,P35244,Q07864,P49005 5 +Activation of bad and translocation to mitochondria 0.5875641661167593 1.7282300605026717 0.0839469863759558 1.0 0.4035978553183184 9 P31946,P31751,P27348 3 +Apoptotic factor mediated response 0.6391582226226323 1.727443739644538 0.0840880009782609 1.0 0.4035978553183184 7 P42771,P42574,P28482 3 +Coenzyme a biosynthesis 0.8851006029839279 1.726798438197465 0.0842038690951887 1.0 0.4035978553183184 3 Q9NVE7 1 +Synthesis of ip3 and ip4 in the cytosol 0.7356630824372672 1.720424775878383 0.0853552565919595 1.0 0.4077106758172637 4 Q13572,P19174,O15357 3 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.550244114429517 1.715465161820369 0.0862599773985497 1.0 0.4085608371979743 21 P28340,P41440,P35244,Q9NX46,P35251,Q07864,P39748,P49005,P18858,P27695 10 +Cytochrome c mediated apoptotic response 0.6971609046456559 1.7121875688226902 0.0868621075973736 1.0 0.4085608371979743 5 P42574,P28482 2 +Deubiquitination 0.3824830818548601 1.709835560750581 0.0872962851445273 1.0 0.4085608371979743 97 P62191,P43686,Q96K76,P60900,P25789,Q15008,Q14694,P85037,Q14258,P25786,P51784,P20618,P25787,O00487,Q13309,Q9NXR7,O14818,O43242,P28066,Q14997,P55036,P49720,O43318,P45974,P61289,Q96FW1,Q96RU2,P28070,P49721,P40818,P49407,Q9UPT9,Q6GQQ9,P20248,O60493,Q9Y5K5,P14735,Q16186,Q86UV5,O94966,Q93008,P28074,O95630,P62195,Q13200 45 +Irs mediated signalling 0.7329749103942556 1.7086802056603954 0.087510202662711 1.0 0.4085608371979743 4 Q99570,P31751,Q06124 3 +Dna strand elongation 0.5300850063810706 1.6912966903482327 0.0907801518414506 1.0 0.4161211493687073 27 P28340,P41440,P35244,P25205,P49005,P18858 6 +Cd28 co stimulation 0.5791442295711784 1.6832808662065566 0.0923207326397124 1.0 0.4178071416943016 9 P62993,Q13153,Q13177,P60953,P31751,Q16512 6 +Polb dependent long patch base excision repair 0.6551026032148914 1.682654574205407 0.0924419802986049 1.0 0.4178071416943016 6 P18858,P39748,Q9NX46,P27695 4 +Signaling by csf3 g csf 0.6294538938569233 1.679941811899656 0.0929686376217153 1.0 0.4178071416943016 7 Q93034,P40763,Q06124,Q15369 4 +Erks are inactivated 0.6292378741391467 1.678882580089111 0.0931749301677564 1.0 0.4178071416943016 7 Q8IV63,P30154,P28482,Q14738 4 +Synthesis of udp n acetyl glucosamine 0.7258064516128943 1.6773165871409563 0.0934805906956315 1.0 0.4178071416943016 4 O95394,Q06210,Q9UJ70 3 +Caspase activation via extrinsic apoptotic signalling pathway 0.6505830306139507 1.6613577771753798 0.0966416124609186 1.0 0.4245552827964288 6 P49327,Q14790 2 +Signal transduction by l1 0.5496228947164481 1.6604545731104958 0.0968230393140057 1.0 0.4245552827964288 11 Q16512,P36507,P67870,P19784 4 +Negative regulation of nmda receptor mediated neuronal transmission 0.6473389308418533 1.646051814647071 0.0997530917372351 1.0 0.4282758582048966 6 Q92796,Q13555,Q15334 3 +Gap junction assembly 0.647279674359823 1.6457720895718668 0.0998106905999183 1.0 0.4282758582048966 6 P68371,Q9BUF5,P04350,Q13885 4 +Transport of connexons to the plasma membrane 0.647279674359823 1.6457720895718668 0.0998106905999183 1.0 0.4282758582048966 6 P68371,Q9BUF5,P04350,Q13885 4 +Darpp 32 events 0.5715629910578531 1.6426927674086225 0.1004465159735161 1.0 0.4282758582048966 9 Q00535,P30154,Q14738,P30153,P17612,Q08209 6 +Platelet sensitization by ldl 0.6815423918921606 1.641280360542903 0.1007392309547463 1.0 0.4282758582048966 5 P30154,Q06124,Q14738 3 +Recruitment of numa to mitotic centrosomes 0.4839308927754583 1.6412156127437585 0.1007526659230224 1.0 0.4282758582048966 36 P68371,P53350,Q7Z460,Q9BT25,Q9BUF5,Q14008,Q99996,Q96CW5,P61163,O94927,Q7Z4H7,P04350,Q9BSJ2,P07437,Q14203,Q9UIS9,P43034,O75935,P07900,Q14204,Q13885,P17612,Q15691 23 +Rna polymerase iii transcription termination 0.6207502867625223 1.6372041588027304 0.1015878183763854 1.0 0.429200813201142 7 Q9NW08,Q9BUI4,O14802,P05455 4 +Unwinding of dna 0.5696589330174765 1.6324825236779634 0.1025778771110177 1.0 0.4316636081033088 9 P33991,Q9BRX5,P33992,P49736,P25205,P33993,Q9BRT9 7 +Synthesis of pips at the late endosome membrane 0.7153524492234066 1.6314669047942183 0.10279183761309 1.0 0.4316636081033088 4 Q99570,Q08AM6,Q13614 3 +Mapk1 erk2 activation 0.8593610032845607 1.6279902557725658 0.1035269519464603 1.0 0.4334411542336743 3 P36507,Q06124 2 +Polymerase switching 0.5435509534824026 1.6245709498938432 0.1042540112150265 1.0 0.4339507937029254 13 P28340,P41440,P49005 3 +Prolonged erk activation events 0.6181640217204535 1.6244815804239328 0.1042730684149475 1.0 0.4339507937029254 7 P28482,P31946,P36507 3 +Trna modification in the nucleus and cytosol 0.536948982285191 1.622460411887532 0.1047048029920616 1.0 0.4344467945043752 20 Q9UBP6,Q9UJA5,Q9NPF4,O60294,Q08J23,Q2VPK5,Q9UET6,Q7Z4G4,Q8TEA1,P57081 10 +Retrograde transport at the trans golgi network 0.5418183636993049 1.6182358483973311 0.1056117799483091 1.0 0.4356094187778924 15 Q5VZE5,Q9UID3,Q96JB2,P20645,O60664 5 +Signaling by erbb2 0.5419641173782012 1.6156329214156069 0.1061737016692405 1.0 0.4366314950303088 12 P07900,P19174,O60610,Q93034,P31751,P40818 6 +Signaling by egfr 0.5381691390318661 1.5939623761219095 0.1109444620630539 1.0 0.4522369567966129 12 P22681,P41240,Q14155,Q06124 4 +Constitutive signaling by egfrviii 0.6677621750821708 1.5784550856099604 0.1144610987203051 1.0 0.4558765822957714 5 P62993,P19174,P07900,P22681 4 +Constitutive signaling by ligand responsive egfr cancer variants 0.6677621750821708 1.5784550856099604 0.1144610987203051 1.0 0.4558765822957714 5 P62993,P19174,P07900,P22681 4 +Signaling by egfr in cancer 0.6677621750821708 1.5784550856099604 0.1144610987203051 1.0 0.4558765822957714 5 P62993,P19174,P07900,P22681 4 +Ephrin signaling 0.6316865435771536 1.571988924787673 0.1159531197492751 1.0 0.4592744790675877 6 O00560,Q16512,Q14155,Q13153 4 +Dscam interactions 0.7018103791764447 1.5718943017082885 0.1159750662969232 1.0 0.4592744790675877 4 Q16512,Q16539 2 +Global genome nucleotide excision repair gg ner 0.455766645632277 1.5513021329570893 0.1208292959263119 1.0 0.4661138218324545 39 P28340,Q86WJ1,P41440,P35244,Q7L5N1,Q92905,Q92759,Q07864,P18074,P61201,P49005,P18858 12 +Copi independent golgi to er retrograde traffic 0.5020916891369364 1.5503586386184507 0.1210554602025295 1.0 0.4661138218324545 29 P47756,P68371,Q9NZ32,Q9BVA1,P43034,O75935,P04350,Q14203,Q9BUF5,Q8TD16,P61163,Q13885,Q14204,O43237,P47755,Q15042,Q9Y6G9 17 +Activation of nima kinases nek9 nek6 nek7 0.6612284500053607 1.5485900175920353 0.1214803071260164 1.0 0.4664575328871901 5 P53350,P14635,O95067 3 +Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.8371058006509471 1.5421865549002391 0.1230282663460333 1.0 0.4698057423653471 3 Q06124 1 +Cd28 dependent vav1 pathway 0.6245237444594745 1.5379878692991362 0.1240515808459803 1.0 0.4711248562183406 6 P62993,Q16512,P60953,Q13153 4 +Er to golgi anterograde transport 0.3463825313036169 1.531728548863848 0.1255894343601546 1.0 0.4743731352190625 80 P47756,P68371,P53621,Q8N6T3,P53992,P35606,Q9BUF5,Q9UBF2,P47755,Q9Y6G9,O00743,O15020,Q9Y6B6,O15027,P61923,Q15436,Q14789,P61163,O15084,O95486,Q5H9R7,Q96JB2,P04350,Q14203,O43237,O95487,P24390,P53618,P48444,Q92734,Q9BVA1,Q92538,Q9Y678,O75935,Q9NZ32,Q14746,Q13885,Q14204,P54920,O94979 40 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.6901263895015883 1.5203526957027305 0.1284223566412801 1.0 0.4827428844339236 4 P28482,P31751 2 +Folding of actin by cct tric 0.5730108939582607 1.5200440518478873 0.1284999044896055 1.0 0.4827428844339236 8 P49368,Q99832,P50991,P40227,P17987,P48643 6 +Cd209 dc sign signaling 0.6543172990738032 1.5169512375406229 0.1292789958778231 1.0 0.4842703559964791 5 P17612,Q16512,Q04206,Q13153 4 +E2f mediated regulation of dna replication 0.5215532073819855 1.501147797159346 0.1333173385464747 1.0 0.4859814612258394 11 Q9UBD5,P14635,P49642,P30154 4 +Bbsome mediated cargo targeting to cilium 0.5928381874958832 1.4994005774736927 0.1337697438830671 1.0 0.4859814612258394 7 P49368,P17987,Q3SYG4,P48643 4 +Regulation of tp53 expression and degradation 0.5214946191165692 1.4984831982304492 0.1340077547318541 1.0 0.4859814612258394 12 P30154,P31751,P42771,P20248,Q9UER7 5 +Dna damage reversal 0.6502185519987 1.4981657686082115 0.134090186974555 1.0 0.4859814612258394 5 Q6P6C2,Q8N3C0 2 +Insulin processing 0.5681214075325554 1.4947878907690817 0.1349698076102812 1.0 0.4859814612258394 8 Q86YB8,Q8TAG9,Q96KP1 3 +Transcriptional regulation by runx1 0.329057134909782 1.49275275263304 0.1355019190542505 1.0 0.4859814612258394 69 O75182,P62191,Q03164,P60900,Q15008,P25786,P20618,P25787,O00487,O14818,P28066,Q14997,P55036,P49720,P61289,P67870,Q99873,P28070,P49721,P19784,Q9HCL2,Q06124,Q9HCE1,Q00534,P28074,P62195,Q13200 27 +Interleukin 20 family signaling 0.8234751794135751 1.489504722492868 0.1363545107036528 1.0 0.4859814612258394 3 P40763 1 +Pyrimidine salvage 0.8220364287847148 1.4839394965056871 0.1378249724820273 1.0 0.4897450133861476 3 Q08623,Q9BZX2 2 +Protein folding 0.4469025624573214 1.4809646454023468 0.1386159948813325 1.0 0.4897450133861476 39 P68371,Q9BUR4,Q15813,Q9BUF5,P51784,Q9Y6D5,P67870,Q9BTW9,P61962,O75347,P40763,P19784,P49368,Q99426,Q9Y2T2,P50991,P04350,P40227,Q99471,P17987,Q99832,Q9BVA1,P36404,Q9UHV9,Q13885,Q15477,P48643 27 +Ca dependent events 0.6121019590080291 1.4788823903258077 0.1391717505816787 1.0 0.4897450133861476 6 P28482,Q13555 2 +E2f enabled inhibition of pre replication complex formation 0.6117359055526705 1.477138181366191 0.1396386005824386 1.0 0.4897450133861476 6 Q9UBD5 1 +Mhc class ii antigen presentation 0.3209883008471842 1.4745507670003335 0.140333359470488 1.0 0.4897450133861476 56 P47756,P68371,P53992,P52732,Q9H0B6,Q9BXS5,Q9BUF5,P47755,Q9Y6G9,O15020,Q9Y6B6,Q15436,Q10567,P33176,P61163,Q99661,O95486,P04350,Q14203,O43237,O95487,P50570,Q9BVA1,Q9NZ32,O75935,Q9UJW0,Q00610,Q13885,Q14204,O95239,O94979 31 +L1cam interactions 0.4080663865342981 1.4668958628334423 0.14240438614519 1.0 0.4897450133861476 45 O00560,P68371,O94973,P15311,P68400,Q9BUF5,Q92796,Q16512,O15020,P36507,Q96S59,P67870,P35241,P19784,P04350,Q15334,Q96P70,P28482,P50570,Q13153,Q9BVA1,Q00610,Q13885,O95239 24 +Negative regulation of fgfr1 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3 +Negative regulation of fgfr2 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3 +Negative regulation of fgfr4 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3 +Negative regulation of fgfr3 signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3 +Spry regulation of fgf signaling 0.6093306023061519 1.4656739540655594 0.1427371331584925 1.0 0.4897450133861476 6 P22681,P28482,Q06124 3 +Ras processing 0.6774193548387022 1.464172902444056 0.1431467120967235 1.0 0.4897450133861476 4 P36404,O43924,O60725 3 +Regulation of plk1 activity at g2 m transition 0.455137879411025 1.461958826125148 0.1437524931378044 1.0 0.4897450133861476 37 P68371,P53350,Q7Z460,O95067,Q9BT25,Q13616,Q14008,Q99996,P61163,Q7Z4H7,O14965,P04350,P07437,Q14203,Q9UIS9,P43034,O75935,P07900,Q14204,P17612,Q15691,P14635 22 +Regulation by c flip 0.6748107990850288 1.4526264737497778 0.1463274915169417 1.0 0.4913416282711362 4 Q14790 1 +Caspase activation via death receptors in the presence of ligand 0.6748107990850288 1.4526264737497778 0.1463274915169417 1.0 0.4913416282711362 4 Q14790 1 +Metabolism of nucleotides 0.3776605896674818 1.4525741093001294 0.1463420389239211 1.0 0.4913416282711362 49 Q08623,P11172,P00813,Q9Y3Z3,P27708,P22392,P31350,P35754,P23921,Q06203,P30520,P00492,P33316,P31939,Q9P2T1,P20839,Q01433,P07741,P04183,Q9BY32,Q9BZX2,P15531,Q9UKK9,P17812,P30566,O15067 26 +Mitotic prometaphase 0.3593042821016838 1.4509101945416556 0.1468048687917571 1.0 0.4917078737844396 96 P68371,P53350,Q7Z460,Q9HBM1,Q8TD19,O95067,Q9BT25,Q9BUF5,Q6P1K2,P50748,Q9Y6G9,Q14008,Q99996,O60566,O14980,O43684,Q96CW5,P67870,Q2NKX8,Q99661,P19784,O43683,Q9H900,Q9P258,Q7Z4H7,P04350,Q9BSJ2,Q14203,P07437,Q92674,Q9NTJ3,O43237,Q9UIS9,Q7Z5K2,Q9HC35,P43034,O75935,P07900,P30154,O95347,Q14738,Q15021,Q15003,Q13885,O43264,Q14204,Q15691,P14635,Q9BPX3 49 +Sealing of the nuclear envelope ne by escrt iii 0.5115928170274602 1.4443554367103304 0.1486390192279472 1.0 0.4941910103180806 11 P68371,Q9BVA1,P04350,Q9BUF5,Q13885,Q8NC56 6 +Long term potentiation 0.6726784636621335 1.443184980676657 0.1489683692973207 1.0 0.4941910103180806 4 Q92796,Q15334 2 +Unblocking of nmda receptors glutamate binding and activation 0.6726784636621335 1.443184980676657 0.1489683692973207 1.0 0.4941910103180806 4 Q92796,Q15334 2 +Ras activation upon ca2 influx through nmda receptor 0.6726784636621335 1.443184980676657 0.1489683692973207 1.0 0.4941910103180806 4 Q92796,Q15334 2 +Ret signaling 0.6378846728413561 1.4415517297740466 0.1494288740874827 1.0 0.4945384166228595 5 P17612,P62993,P19174,Q06124 4 +Signaling by flt3 fusion proteins 0.6705534029025779 1.4337731875355555 0.1516369988071639 1.0 0.4977306531100521 4 P62993,Q92614 2 +Interleukin 2 family signaling 0.6704041984553126 1.4331122780354453 0.1518257531788935 1.0 0.4977306531100521 4 P40763,O15357 2 +Intrinsic pathway for apoptosis 0.5024379403920903 1.4303446030902582 0.1526181392173993 1.0 0.499151090616906 22 P55210,P31946,P27348,Q14790,P31751,P42771,P42574,P28482,P40763 9 +Dna double strand break repair 0.3086179821955417 1.4193282934588471 0.155803327086029 1.0 0.503643313138559 58 P28340,P41440,P35244,Q99504,P49005,Q04323,Q07864,O60921,P20248,Q9UQ84,Q13535 11 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5734927812696495 1.403370866654097 0.1605062758281916 1.0 0.5152510933052804 7 Q00653,O43318,P09429,O15111 4 +Aurka activation by tpx2 0.46612758361494 1.377968108186724 0.1682131348582181 1.0 0.5350486440570323 32 P68371,P53350,Q7Z460,Q9BT25,Q14008,Q99996,P61163,Q7Z4H7,O14965,P04350,P07437,Q14203,P17612,Q9UIS9,P43034,O75935,P07900,Q14204,Q15691 19 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4950714565606595 1.3740233543732423 0.1694344321503593 1.0 0.537702878285387 21 P28340,P41440,P35244,Q07864,P49005 5 +Signaling by alk 0.622227001483316 1.3695375454213443 0.1708313069185545 1.0 0.5409009490131909 5 P40763 1 +Glutathione synthesis and recycling 0.5887627017334099 1.3674520470683424 0.1714836580262675 1.0 0.5411682778823503 6 Q8WUX2,O75223,P48506,Q96KP4,P48507 5 +Rna polymerase iii transcription initiation from type 3 promoter 0.5881036705085807 1.3643003510543483 0.1724730554689792 1.0 0.5411682778823503 6 Q9NW08,Q9BUI4,O14802 3 +Rna polymerase iii chain elongation 0.5881036705085807 1.3643003510543483 0.1724730554689792 1.0 0.5411682778823503 6 Q9NW08,Q9BUI4,O14802 3 +Transport to the golgi and subsequent modification 0.3347124850296098 1.3619020823772792 0.1732287889388533 1.0 0.5423153527590227 82 P47756,P68371,P53621,Q8N6T3,P53992,P35606,Q9BUF5,Q9UBF2,P47755,Q9Y6G9,O00743,O15020,Q9Y6B6,O15027,P61923,Q15436,Q14789,P61163,O15084,O95486,Q5H9R7,Q96JB2,P04350,Q14203,O43237,O95487,P24390,P53618,P26572,P48444,Q92734,Q9BVA1,Q92538,Q9Y678,O75935,Q9NZ32,Q14746,Q13885,Q14204,P54920,O94979 41 +Cellular response to chemical stress 0.3264955194052045 1.3532256365621085 0.17598355755379 1.0 0.5455572412687759 76 O75182,P62191,O75880,P43686,P60900,P62333,P53004,P25789,Q5RI15,Q15008,P00390,P68400,P25786,P20618,P25787,Q86X55,O00487,Q13309,Q13616,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P67870,Q9UNM6,Q15648,P40763,P28070,P49721,P19784,P30043,P48556,P30041,P28072,P25788,Q13618,O00231,P14854,P30519,P28074,P62195,Q13200 46 +Separation of sister chromatids 0.364747544380337 1.3500132336645947 0.1770117379944014 1.0 0.5455572412687759 108 P68371,P62191,P43686,P60900,Q13200,P53350,Q7Z460,Q9HBM1,P25789,Q15008,Q9BUF5,P25786,Q6P1K2,P20618,P25787,P50748,O00487,Q9Y6G9,Q14008,O60566,O14818,O14980,O43242,P28066,Q14997,O43684,P55036,P49720,P61289,O75832,P28070,P49721,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,P04350,Q9UJX4,Q92674,O43237,Q29RF7,Q7Z5K2,P43034,P30154,Q14738,P28074,O43264,Q13885,Q14204,Q15691,P62195,Q16763 53 +Nuclear receptor transcription pathway 0.6491236353221433 1.3387589975983405 0.1806491429066741 1.0 0.5518363075383483 4 P10589 1 +Pkmts methylate histone lysines 0.4932705784234742 1.3375779103680523 0.181034069235602 1.0 0.5518363075383483 17 Q03164 1 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6145256659936187 1.3340785660224035 0.1821781095449113 1.0 0.5525655189760987 5 P30154,P49642 2 +Regulation of runx1 expression and activity 0.7829202747088548 1.3324600134947546 0.1827090727685147 1.0 0.5525655189760987 3 Q00534,Q06124 2 +Dcc mediated attractive signaling 0.64653738949343 1.3272846073159916 0.1844145537112727 1.0 0.5525655189760987 4 O00401,Q14185 2 +Downregulation of erbb2 signaling 0.5570946622478793 1.3217709923800185 0.1862444204299682 1.0 0.5567306331132384 7 P07900,Q93034,P31751,P40818 4 +Apoptosis 0.3406400798515645 1.3162359559770411 0.1880948589562807 1.0 0.5610554805777473 90 P62191,P55210,P31946,P60900,Q15008,P42771,P25786,P20618,P25787,O00487,P27348,P63104,O14818,P35611,P28066,Q14997,O00429,P55036,P49720,P61289,P09429,P40763,P28070,P49721,Q14790,P31751,P55212,P49327,P28482,P28074,P42574,P62195,Q13200 33 +Diseases of mitotic cell cycle 0.4892129700957885 1.312868905376213 0.1892271262909814 1.0 0.5632242088746559 12 Q9UJX5,P11802,Q9UJX4,Q00534,Q9UER7,Q13309,Q16763 7 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5318745267111231 1.306924269626773 0.1912384326173684 1.0 0.5653977339561054 8 Q92796,P28482,Q13555,Q15334 4 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4866737236173046 1.3068715686162495 0.1912563335388746 1.0 0.5653977339561054 10 O14965,Q99873,P14635 3 +Inactivation of csf3 g csf signaling 0.6080365082614785 1.3041910262357774 0.1921684587812118 1.0 0.5653977339561054 5 P40763,Q15369 2 +Formation of incision complex in gg ner 0.4879871172667654 1.3021109084811993 0.1928784746606842 1.0 0.5656140923593904 15 Q86WJ1,Q16531,Q9UGN5,Q13619,P35244,O75925,Q13620,Q92759,P09874,P18074,P27694,P54727 12 +Response of eif2ak1 hri to heme deficiency 0.7725859683141175 1.2924375736674694 0.1962056516500752 1.0 0.573168673348937 3 P08243 1 +Ncam signaling for neurite out growth 0.5727927248673693 1.2910345543786748 0.1966916958183042 1.0 0.573168673348937 6 O15020,P28482 2 +Regulation of lipid metabolism by pparalpha 0.4790659821873173 1.2837761719839018 0.1992202831990672 1.0 0.5769087367639656 22 P11310,Q96EK7,Q9Y2X0 3 +Uptake and function of anthrax toxins 0.5686269702427817 1.2710930879370457 0.2036955340493946 1.0 0.5886419798932611 6 P36507,Q02750,P52564,P45985 4 +Oncogene induced senescence 0.5465102905283148 1.2690622336998805 0.2044188686504435 1.0 0.5895066959006567 7 P42771,Q00534,P28482,P11802 4 +Interleukin 17 signaling 0.4783687732301156 1.262788828545566 0.2066650805660497 1.0 0.5935216156752254 20 Q13616,Q8IV63,P45985,P30154,P52564,Q16539,Q14738,O43318,Q02750,P51452,P28482,Q15418,O15111 13 +Nucleotide excision repair 0.3357888356746234 1.261160319173427 0.2072510919289927 1.0 0.5935360864269589 52 P28340,Q86WJ1,P41440,P35244,Q92905,Q92759,Q07864,P18074,P61201,P49005,P18858 11 +Mrna capping 0.4798076581494335 1.2540023573729542 0.2098411485925948 1.0 0.5935360864269589 15 O60942,Q92759,P35269 3 +Telomere c strand lagging strand synthesis 0.4741994488524723 1.2533026909437366 0.210095569503522 1.0 0.5935360864269589 22 P28340,P41440,P35244,P49005,P18858 5 +Wnt mediated activation of dvl 0.7618742446289175 1.250984416268213 0.2109401630898688 1.0 0.5935360864269589 3 P67870 1 +Regulation of signaling by cbl 0.6287267061668091 1.2482717713011642 0.2119315482071364 1.0 0.5946255672406363 4 P46109,P22681 2 +Ephb mediated forward signaling 0.4785742020456668 1.2475853772822998 0.2121829362239968 1.0 0.5946255672406363 16 O00401,Q13464,Q13153,P61160,P60953,O15145,P23528,O75116,P07947,Q16512,Q92747 11 +Heme degradation 0.6276675239364387 1.2435750305249669 0.2136560107125107 1.0 0.5975490038036014 4 P53004,P30519 2 +Signaling by moderate kinase activity braf mutants 0.4773939320209304 1.2419771312653975 0.2142449997635593 1.0 0.5975625805474319 13 Q13555,P31946,P41240,P36507,P46940,Q9Y490,P28482,P30086,P49407 9 +Transcription coupled nucleotide excision repair tc ner 0.388217474143616 1.235207358635973 0.2167533413042339 1.0 0.5990771644353867 44 P28340,P41440,P35244,Q92905,Q92759,Q07864,P18074,P61201,P49005,P18858 10 +Pi3k akt signaling in cancer 0.4755912060060332 1.2345039106889135 0.2170151903879316 1.0 0.5990771644353867 12 O15111,Q96B36,P31751,Q06124 4 +Extension of telomeres 0.4435469008833466 1.218251852280398 0.2231282806216941 1.0 0.609328703465923 32 P28340,P41440,P35244,Q9BUR4,P49005,P49642,P18858,O15084 8 +Anchoring of the basal body to the plasma membrane 0.4465263651345348 1.215071509901017 0.2243388186159074 1.0 0.6108437268791155 31 P68371,Q14008,Q99996,P43034,O75935,P53350,Q7Z460,Q7Z4H7,P07900,Q14204,P04350,P07437,Q14203,Q9BT25,P61163,P17612,Q15691,Q9UIS9 18 +Rho gtpases activate formins 0.2994862037901371 1.2110751409667255 0.2258666077762161 1.0 0.6108437268791155 64 P68371,P53350,Q9HBM1,Q7Z460,Q9BUF5,Q6P1K2,P50748,Q9Y6G9,Q14008,O60566,O14980,O43684,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,P04350,O43237,P43034,O60610,P30154,Q14738,O43264,Q13885,P35080,Q14204,P07737,Q15691 29 +Autophagy 0.2985234054755694 1.2058855387579357 0.2278616273199363 1.0 0.6146494290479415 56 Q8NCE2,Q9NT62,P04350,Q99570,Q15382,Q9Y4P1,P67870,Q13501,O43237,O60664,O95352,P19784 12 +Abc family proteins mediated transport 0.3448090973543726 1.2006552261953116 0.2298849688972879 1.0 0.6146494290479415 50 P62191,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,O75832,P28070,P49721,P05198,Q8NE71,P28074,P62195,Q13200 24 +Fceri mediated ca 2 mobilization 0.5855192868477117 1.200511385274318 0.2299407936006687 1.0 0.6146494290479415 5 P19174,Q08209 2 +Translesion synthesis by polk 0.4676372407472392 1.1988184509444892 0.2305985465040885 1.0 0.6152245290608119 10 P35244 1 +Signaling by wnt 0.3338846393585081 1.1953580655919502 0.2319471622200564 1.0 0.617532796667084 93 O94973,P62191,O75436,P43686,P60900,P62333,P25789,Q15008,P68400,P25786,P20618,P25787,O00487,Q13616,Q9HCK8,Q96QK1,P63104,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,O43318,P61289,Q9Y3A6,O75832,P67870,Q9UNM6,Q08209,P28070,P49721,P40818,P19784,P48556,P28072,P25788,Q13618,O00231,P31751,O60493,Q9HCE1,Q9Y4A5,P30154,Q14738,Q00610,P28074,P07737,P62195,P09471,Q13200,Q04727 53 +Signaling by insulin receptor 0.4692956012758755 1.1943214040318122 0.2323522680984784 1.0 0.617532796667084 17 Q9Y487,Q9Y5K8,P31751,Q06124,P28482 5 +Metabolism of nitric oxide nos3 activation and regulation 0.5290450809080541 1.1821361128145034 0.2371516972823792 1.0 0.6261686836818638 7 Q9Y314,P07900,O00401,P50570 4 +Toll like receptor tlr1 tlr2 cascade 0.4589415149768736 1.1780527205328368 0.2387755890411966 1.0 0.6274065572159988 24 Q13616,Q00653,Q8IV63,Q04206,P45985,P30154,P52564,Q16539,Q14738,O43318,Q02750,P09429,P51452,P28482,Q15418,O15111 16 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6126045400238851 1.1768406489472274 0.239259114782131 1.0 0.6274908859380417 4 P17612,P30154,Q14738 3 +Mastl facilitates mitotic progression 0.5774995496863085 1.1636376164719564 0.2445709003992073 1.0 0.6368133201409261 5 P30154,P14635,P30153 3 +Pecam1 interactions 0.7386969179784478 1.161495167297805 0.2454405873622707 1.0 0.6368526934112324 3 Q06124 1 +Wnt ligand biogenesis and trafficking 0.5769345682700949 1.1610417092201502 0.2456249379441393 1.0 0.6368526934112324 5 O75436,Q9Y3A6,Q96QK1,O60493 4 +Signaling by braf and raf1 fusions 0.4542231559205976 1.1600317079846612 0.2460358966631883 1.0 0.6368526934112324 25 P31946,Q99996,Q13555,O43252,P41240,P36507,P28482,P51114,O00203,P46940,Q96PU8,Q9Y490,P30086,O95352,P49407 15 +Uptake and function of diphtheria toxin 0.6075268817204214 1.1543798095326565 0.2483444891196238 1.0 0.6381098293942095 4 P07900,P08238,P13639 3 +Ros and rns production in phagocytes 0.459785906361445 1.154347195786129 0.2483578544620628 1.0 0.6381098293942095 10 Q9Y5K8 1 +Diseases of dna repair 0.4594845757440756 1.1526421687169954 0.2490572874309407 1.0 0.6387262537435564 10 Q9UQ84,P20585 2 +Dna damage bypass 0.4545157114347333 1.149897500351981 0.2501860905525843 1.0 0.6404395319854369 24 P28340,P41440,P35244,Q07864,P49005 5 +Activation of caspases through apoptosome mediated cleavage 0.7346048571805289 1.1457374365307718 0.2519038088204062 1.0 0.6406073671729514 3 P42574 1 +Smac xiap regulated apoptotic response 0.7346048571805289 1.1457374365307718 0.2519038088204062 1.0 0.6406073671729514 3 P42574 1 +Mtorc1 mediated signalling 0.4588678616195771 1.143282604031259 0.25292127526807 1.0 0.6406073671729514 11 Q96B36,P31946,Q15382,Q04637,P62753 5 +Signaling by erythropoietin 0.7327560465810704 1.1386232158515237 0.2548603410407168 1.0 0.6406073671729514 3 P46109,P19174 2 +Downstream signaling of activated fgfr1 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2 +Downstream signaling of activated fgfr2 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2 +Downstream signaling of activated fgfr3 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2 +Downstream signaling of activated fgfr4 0.7327560465810518 1.1386232158514515 0.2548603410407468 1.0 0.6406073671729514 3 P19174,Q06124 2 +Gab1 signalosome 0.7327560465810501 1.1386232158514449 0.2548603410407497 1.0 0.6406073671729514 3 P41240,Q06124 2 +Toll like receptor cascades 0.4284620925026767 1.1366660678479814 0.2556779094832788 1.0 0.6415023360681544 33 P52564,Q16539,Q99570,Q13546,O15111,Q00653,O43318,P09429,P51452,Q8IV63,Q14790,Q06124,P28482,Q04206,P50570,P45985,P30154,Q9UHD2,Q14738 19 +Resolution of sister chromatid cohesion 0.2957354483697372 1.1351021832639367 0.2563325069071278 1.0 0.6419859181998336 66 P68371,P53350,Q9HBM1,Q7Z460,O95067,Q9BUF5,Q6P1K2,P50748,Q9Y6G9,Q14008,O60566,O14980,O43684,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,P04350,Q92674,O43237,Q7Z5K2,P43034,P30154,Q14738,O43264,Q13885,Q14204,Q15691,P14635 30 +Purinergic signaling in leishmaniasis infection 0.5703615177771195 1.130862093573486 0.2581131400855674 1.0 0.6434732850443518 5 Q00653,Q04206,P08238,Q9Y2Z0 4 +Cargo trafficking to the periciliary membrane 0.4580346552054514 1.129676166340411 0.2586127035936498 1.0 0.6434732850443518 18 P49368,Q9UPT5,Q92538,P50991,Q8TAG9,Q96KP1,P36405,O43924,P17987,Q3SYG4,P48643 11 +Microrna mirna biogenesis 0.4557620705951447 1.1256192179774596 0.2603267300080827 1.0 0.6434732850443518 11 Q9HAV4 1 +Tnfr1 induced proapoptotic signaling 0.6007184657267033 1.1243013723396795 0.2608851963901282 1.0 0.6434732850443518 4 Q6GQQ9,Q14790 2 +Negative feedback regulation of mapk pathway 0.6006076177744548 1.1238120759808017 0.2610927573849024 1.0 0.6434732850443518 4 P36507 1 +Negative regulation of the pi3k akt network 0.4566178472200065 1.1219636012402574 0.261877916387923 1.0 0.6442660243879875 13 P62993,P30154,P31751,Q14738,Q06124,P28482 6 +Homology directed repair 0.3857732809156454 1.1180022692748235 0.2635660241760353 1.0 0.6472734515983908 42 P28340,P41440,P35244,P49005,Q07864,O60921,P20248,Q9UQ84,Q13535 9 +Tnf signaling 0.4537765456613296 1.1143371784776877 0.2651345629485799 1.0 0.64945836273882 11 O15111,O43318,Q14790,Q96BN8 4 +Transcriptional regulation of white adipocyte differentiation 0.4535353545454717 1.1042249110089428 0.2694955861062866 1.0 0.6526112625221925 13 Q04206,Q86X55,Q9Y2X0,P11802,Q9NPJ6,Q15648,Q96EK7 7 +Mitotic spindle checkpoint 0.2815527595789066 1.1025604454257196 0.2702180954491076 1.0 0.6532228742161036 57 P53350,Q9HBM1,Q7Z460,Q6P1K2,P50748,Q9Y6G9,Q9H1A4,Q14008,O60566,O14980,O43684,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,Q9UJX4,Q92674,O43237,Q9UJX5,P43034,P30154,Q14738,O43264,Q14204,Q15691,Q16763 27 +Signaling by met 0.4519613732761577 1.0904884231488805 0.2754980501876627 1.0 0.6611695400991412 16 P22681,Q96N67,Q96P70,P40763,P40818 5 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4507762601599916 1.0839731230493983 0.2783767158202566 1.0 0.6611695400991412 15 Q00653,Q04206,Q14790,Q16539,O43318,P08238,O15111 7 +Egfr downregulation 0.4848928260758538 1.0636496180501236 0.2874874559323865 1.0 0.6666503321715846 8 Q14155 1 +Nod1 2 signaling pathway 0.4640877407788073 1.0619057962881926 0.2882784534542555 1.0 0.6667338607344678 9 O15111,O43318,Q14790,Q16539 4 +Diseases of immune system 0.5542737586300359 1.0572135918008847 0.2904141180818655 1.0 0.6683371260493264 5 Q00653,P09429,O15111 3 +Downregulation of erbb2 erbb3 signaling 0.9432835820895532 1.055610785883384 0.2911460711330205 1.0 0.6689141138428074 2 P31751 1 +Diseases of mismatch repair mmr 0.7097641086891445 1.0504803531336542 0.2934973192325678 1.0 0.6732034220020945 3 P20585,P52701 2 +Intraflagellar transport 0.4435415592250075 1.0438353984712905 0.2965615509838581 1.0 0.6778361423835731 14 Q9BW83,Q92973,P04350,Q9BUF5,Q13885 5 +Generation of second messenger molecules 0.5507869467929454 1.041303253172572 0.2977348273622349 1.0 0.6778361423835731 5 P19174,Q13153,Q16512 3 +Rhou gtpase cycle 0.4430039463278277 1.0400061003632248 0.2983370664787435 1.0 0.6778361423835731 18 P62993,Q13153,Q03001,Q13177,P60953,P46940,Q93008,Q00610,Q14155,Q16512,O43396 11 +Trna aminoacylation 0.3992840030583358 1.0371335639783923 0.2996736148166961 1.0 0.6778361423835731 37 Q9P2J5,Q13155,P54136,Q15181,P26639,P07814,P47897,P41252,P54577,Q9NSD9,Q96I59,O43776,P49591,P41250,Q5T160,Q9H2U2,P26640,P49589,P23381,Q9Y285 20 +Signaling by erbb2 ecd mutants 0.5492084537468944 1.034107824242273 0.3010857588866817 1.0 0.6778361423835731 5 P62993,P19174,P07900 3 +Signaling by erbb2 in cancer 0.5492084537468944 1.034107824242273 0.3010857588866817 1.0 0.6778361423835731 5 P62993,P19174,P07900 3 +Base excision repair 0.4280415951322225 1.0323178370944706 0.301923247777111 1.0 0.6778361423835731 28 P28340,P41440,P35244,Q07864,P29372,P49005,P18858 7 +Signaling by erbb4 0.5183830034222363 1.0313233628692566 0.3023892059886859 1.0 0.6778361423835731 6 P61201,P16949,Q15334 3 +Activation of nmda receptors and postsynaptic events 0.4299493161731739 1.0299714692783923 0.3030233988795872 1.0 0.6778361423835731 27 P68371,Q13555,P04350,Q15334,Q9BUF5,Q14155,Q13885,Q92796,P28482,Q14012 10 +Traf6 mediated nf kb activation 0.4777821564385169 1.027102824804751 0.3043720486813734 1.0 0.6790965452120531 8 Q00653,Q14258,P09429 3 +Antigen processing cross presentation 0.305647638227096 1.0217299444054124 0.3069087344010404 1.0 0.6814746658425658 53 P62191,P60900,P43686,P25789,Q15008,P25786,P20618,P25787,O00487,O15111,O14818,O43242,P28066,Q14997,P55036,P49720,P61289,P09429,P28070,P49721,P60059,P28074,P62195,Q13200 24 +Rap1 signalling 0.6972230516572144 1.0027255831170718 0.3159932827704632 1.0 0.6936265718329245 3 P31946,P63104 2 +Ionotropic activity of kainate receptors 0.6967435950707329 1.0009053483864565 0.3168725705855446 1.0 0.6936265718329245 3 Q92796 1 +Nrcam interactions 0.6967435950707329 1.0009053483864565 0.3168725705855446 1.0 0.6936265718329245 3 Q92796 1 +Signaling by ntrk3 trkc 0.6949366749455661 0.9940493598328408 0.3201988374494919 1.0 0.6965201628400529 3 P19174 1 +Traf6 mediated irf7 activation 0.5704006161444459 0.9911603509353302 0.3216072876397544 1.0 0.6974011385635861 4 Q14258 1 +Oncogenic mapk signaling 0.4163543019430996 0.988298575652049 0.3230064427976287 1.0 0.6980720485205444 30 P21359,P31946,Q99996,P36507,P41240,Q99956,P51114,O00203,Q96PU8,P28482,P30086,O95352,P49407 13 +Mtor signalling 0.4334616600345596 0.9824006673815204 0.325902497677331 1.0 0.7012453123397681 17 Q96B36,P31946,P31751,Q15382,Q04637,P62753,Q9Y376 7 +Signalling to erks 0.4284830793946381 0.9783728507645248 0.3278899507761204 1.0 0.7033441845351964 10 P31946,P36507,Q16539,P46109,P28482 5 +Rho gtpases activate wasps and waves 0.4312121837907651 0.9724919037058324 0.3308058907518569 1.0 0.70359455925136 19 P62993,O00401,Q9UQB8,P61160,P60953,O15145,P28482,Q9NZQ3,Q7L576 9 +Regulation of innate immune responses to cytosolic dna 0.5658391265800239 0.971282385077156 0.3314076780545885 1.0 0.70359455925136 4 P19474 1 +Bmal1 clock npas2 activates circadian gene expression 0.6867721707972392 0.9631516703807405 0.3354714147090223 1.0 0.7079698867638203 3 Q15648,P43490 2 +Diseases of signal transduction by growth factor receptors and second messengers 0.368482293372352 0.9627977449241316 0.335649032645581 1.0 0.7079698867638203 144 P62191,P62993,P31946,P43686,P60900,Q13200,P25789,P41240,Q15008,Q99956,Q92614,P25786,P20618,P25787,O00487,O15111,P22681,Q99996,Q9NR09,O14818,P19174,O43242,P28066,Q14997,P51114,P55036,P36507,Q14789,P61289,P49720,P13984,P33176,Q96PU8,O75832,P31939,P40763,P28070,P49721,P49407,P21359,P35579,Q9H6R7,P31751,Q14203,Q06124,P62753,Q9Y490,P30086,P28482,O95352,Q96B36,Q9HC35,Q92734,P07900,P30154,O00203,P35269,Q14738,P49589,P28074,Q13501,P62195,P26641 63 +Dual incision in tc ner 0.4031166390348242 0.958386740878674 0.3378677786965793 1.0 0.7097754679309625 33 P28340,P41440,P35244,Q92759,Q07864,P49005 6 +Receptor mediated mitophagy 0.5621265915802149 0.955141762361659 0.3395060120266668 1.0 0.711784851760282 4 P67870 1 +Ngf stimulated transcription 0.683003532689886 0.9489373001107068 0.3426525022403108 1.0 0.7156034362622726 3 Q00535 1 +Toll like receptor 9 tlr9 cascade 0.4191032532766927 0.9475875972369004 0.3433394426562461 1.0 0.7156034362622726 26 Q00653,Q8IV63,Q04206,P45985,P30154,P52564,Q16539,Q14738,Q99570,O43318,P09429,P51452,P28482,O15111 14 +Cell cycle checkpoints 0.3698476860636454 0.9457747743102912 0.3442634745024699 1.0 0.7163566310754989 147 P62191,P33992,P31946,P43686,P60900,P62333,P53350,Q7Z460,P25205,Q9HBM1,P25789,Q15008,O95067,P42771,Q92547,P25786,Q6P1K2,P25787,P50748,Q9UQ84,P20618,O00487,O96017,Q9Y6G9,Q13200,Q9H1A4,Q14008,Q9NXR7,O60566,P35244,P27348,P63104,O14980,O14818,O43242,P28066,Q14997,O43684,P55036,P49720,O60921,P61289,O75832,P27694,O14777,P28070,P49721,Q99661,Q2NKX8,O43683,Q9UBD5,Q9H900,P33991,P49736,Q9P258,Q9UJX4,P20248,Q92674,P30307,O43237,Q13535,Q99741,P43034,Q9UJX5,P30154,Q14738,P14635,P28074,O43264,Q14204,Q15691,P62195,Q16763 73 +Telomere maintenance 0.3682569378498406 0.935808120292414 0.349371989836416 1.0 0.7231492310943015 41 P28340,P41440,P35244,Q9BUR4,Q9UER7,P49005,P49642,P18858,O15084 9 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.5574534380619665 0.934876743661984 0.3498518235672216 1.0 0.7231492310943015 4 O43318 1 +Foxo mediated transcription 0.4209239304293978 0.9234219765210192 0.3557873434537617 1.0 0.7313080840783428 12 Q96EB6,P31946,P31751,P27348 4 +Signaling by ctnnb1 phospho site mutants 0.4951165294856486 0.9216522664850336 0.3567099863346161 1.0 0.7313080840783428 6 Q14738 1 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.4951165294856486 0.9216522664850336 0.3567099863346161 1.0 0.7313080840783428 6 Q14738 1 +Beta catenin phosphorylation cascade 0.4951165294856486 0.9216522664850336 0.3567099863346161 1.0 0.7313080840783428 6 Q14738 1 +Rna polymerase iii transcription 0.4199114488672818 0.9177633307515388 0.3587427837115271 1.0 0.7343924438277212 12 Q9NW08,Q9BUI4,O14802,P05455 4 +Interconversion of nucleotide di and triphosphates 0.4220159952810619 0.9158203335098036 0.3597611368387889 1.0 0.7353889360674704 17 Q9Y3D8,Q9H773,P15531,P00568,P33316,P00390,P17812,P30085,P22392,P31350,P35754,P23921,P04818 13 +Signaling by ptk6 0.4182319351291855 0.9144270479972478 0.3604924946813272 1.0 0.7353889360674704 11 P22681,P40763,Q14185 3 +Signaling by alk in cancer 0.3925513673241786 0.9075505497136226 0.3641157307508482 1.0 0.7387713895900294 34 P62993,P35579,Q9HC35,Q92734,Q9NR09,Q9H6R7,P19174,Q14203,P49589,Q00610,P33176,Q13501,P62753,P28482,P31939,P40763,O94979,P26641 18 +Fasl cd95l signaling 0.8982089552238819 0.903101077864897 0.3664722520067398 1.0 0.7393199899298378 2 Q14790 1 +Signaling by leptin 0.8979104477611939 0.9021059837574388 0.3670005705407109 1.0 0.7393199899298378 2 P40763 1 +Regulation of beta cell development 0.5486031806642321 0.8966726958363922 0.3698935944226811 1.0 0.7403061357668591 4 P31751 1 +Dap12 signaling 0.6677904775904895 0.891902950737352 0.3724449529349218 1.0 0.7405915893497147 3 P19174 1 +Regulation of tnfr1 signaling 0.4121477341605519 0.8879754541248486 0.374553954935934 1.0 0.7413920981057122 10 O15111,Q6GQQ9,Q14790,Q96BN8 4 +Signaling by kit in disease 0.5456989247311683 0.8841902861585955 0.3765935011834611 1.0 0.7413920981057122 4 P07947,P62993,P40763 3 +Association of tric cct with target proteins during biosynthesis 0.4159579436136823 0.88262013087456 0.3774415481709747 1.0 0.7413920981057122 19 Q9Y2T2,Q9BUR4,P40763,P51784,Q15477,P61962,P17987,Q9Y6D5,P48643 9 +Formation of the early elongation complex 0.4145865471916424 0.8730270525105825 0.3826483326007004 1.0 0.7459764127839742 17 P18074,Q92759,P18615,P35269 4 +G protein beta gamma signalling 0.4463225947675224 0.8673072163465935 0.385773703793288 1.0 0.747873707493264 8 P31751 1 +Translesion synthesis by polh 0.4109399857757285 0.8626613591491705 0.3883236835206376 1.0 0.7484679148607702 13 P41440,P35244 2 +Displacement of dna glycosylase by apex1 0.8859701492537313 0.8624937123023199 0.3884158916510749 1.0 0.7484679148607702 2 P29372 1 +Regulation of tp53 activity through phosphorylation 0.3750325438159651 0.8586593253821438 0.3905284972649385 1.0 0.748737394756227 37 P35244,O14965,Q92547,O60921,P20248,P67870,Q9UQ84,Q13535,P19784 9 +Molybdenum cofactor biosynthesis 0.53912783751492 0.8560569296012975 0.3919662906518772 1.0 0.7492749116394054 4 O96007,Q9NZB8,Q9Y697 3 +Dag and ip3 signaling 0.4439107964415129 0.8552260871207301 0.3924259968874009 1.0 0.7492749116394054 8 P19174,Q13555 2 +Deactivation of the beta catenin transactivating complex 0.4070276395480022 0.8526147003767144 0.3938730077444359 1.0 0.7498605353752564 11 Q9HCK8,P31751,P63104,Q04727 4 +Negative regulation of flt3 0.8823880597014944 0.8506863695039919 0.3949435968724768 1.0 0.7498605353752564 2 P22681 1 +Pd 1 signaling 0.8823880597014924 0.8506863695039862 0.3949435968724799 1.0 0.7498605353752564 2 Q06124 1 +The nlrp3 inflammasome 0.4796798824155261 0.8498112173593368 0.395430052107959 1.0 0.7498605353752564 6 Q00653,Q04206,P08238,Q9Y2Z0 4 +Inflammasomes 0.4796798824155261 0.8498112173593368 0.395430052107959 1.0 0.7498605353752564 6 Q00653,Q04206,P08238,Q9Y2Z0 4 +Pp2a mediated dephosphorylation of key metabolic factors 0.6560361936382422 0.8482675366361441 0.3962889925723152 1.0 0.7504655308930765 3 Q14738 1 +Synthesis of diphthamide eef2 0.6537836444793921 0.8399536338115924 0.4009343839750605 1.0 0.7551474169719975 3 Q9BQC3 1 +Synthesis of gdp mannose 0.878805970149256 0.838916244225299 0.4015163115214726 1.0 0.7552201258658281 2 P34949 1 +Methylation 0.4200098956892839 0.8285480283552431 0.4073602069759265 1.0 0.7631141343619109 9 Q9NZL9,P23526,Q99707,P31153,P78417 5 +Tgf beta receptor signaling activates smads 0.4191223382240115 0.8239468909801828 0.4099697352406855 1.0 0.7651829941840071 9 O14980,Q9Y5K5,P61081,P22681 4 +Programmed cell death 0.309775273004117 0.8230686021393276 0.410468982582608 1.0 0.7651829941840071 101 P62191,P55210,P41440,P31946,P60900,Q15008,P42771,P25786,P20618,P25787,O00487,P27348,P63104,O14818,P35611,P28066,Q14997,O00429,P55036,P49720,P61289,P09429,P40763,P28070,P49721,Q14790,P31751,P55212,P49327,P28482,P28074,P42574,P62195,Q13200 34 +Transport of inorganic cations anions and amino acids oligopeptides 0.4186361168991424 0.8214284299635898 0.411402275216955 1.0 0.7651829941840071 9 Q70HW3 1 +Role of second messengers in netrin 1 signaling 0.873134328358212 0.8203591348485277 0.4120114043401719 1.0 0.7651829941840071 2 Q00169 1 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.397914911630766 0.8029524102584754 0.4220022415632245 1.0 0.7788546179333645 11 Q9BQC3,O60725,P63241 3 +G alpha 12 13 signalling events 0.3989987681069816 0.802310840135368 0.4223731734186393 1.0 0.7788546179333645 12 O75116,Q14155 2 +Tp53 regulates transcription of cell cycle genes 0.4021753227129557 0.8021147116399884 0.4224866056991057 1.0 0.7788546179333645 18 O95628,O14965,Q9UIV1,Q92600,P30307,P14635,P20248,Q99873,Q86X55,A5YKK6 10 +Synthesis of ip2 ip and ins in the cytosol 0.6422996149193752 0.7978329223931002 0.4249674533312491 1.0 0.7823904107687898 3 Q96PE3 1 +Tp53 regulates transcription of cell death genes 0.4501879030790146 0.7964945386121753 0.4257446486116174 1.0 0.7827844729763865 7 P55212,P49327,P24386 3 +Smad2 smad3 smad4 heterotrimer regulates transcription 0.49530781758531 0.7925391455719196 0.4280463759900332 1.0 0.783898077342642 5 P28482 1 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6396122455553861 0.7880443458236163 0.4306707671411407 1.0 0.783898077342642 3 P40763 1 +Vxpx cargo targeting to cilium 0.4303145582821154 0.7877175036669283 0.4308619648127902 1.0 0.783898077342642 8 Q92538,Q96KP1 2 +Met activates ras signaling 0.522730325574019 0.7866007197684194 0.4315156378010061 1.0 0.7840610935207823 4 Q96S59,Q96P70 2 +Hiv transcription initiation 0.3982868595353141 0.7847237266351711 0.4326155684439206 1.0 0.7849833254218191 15 P18074,Q92759,P35269 3 +Glucuronidation 0.6363093460734448 0.7760513476678209 0.4377186685135537 1.0 0.7898832017028177 3 O60701,Q9NUJ1 2 +Synaptic adhesion like molecules 0.4457167023731042 0.7753374371807942 0.4381402931073039 1.0 0.7898832017028177 7 Q92796 1 +Signaling by mapk mutants 0.8591044776119432 0.7748980087258474 0.43839992889137 1.0 0.7898832017028177 2 Q99956 1 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.4628370632328193 0.7725885187487419 0.4397659414435364 1.0 0.7898832017028177 6 Q14258,Q14790 2 +Activation of bh3 only proteins 0.3934418601079638 0.7721735555008383 0.4400116417110349 1.0 0.7898832017028177 12 P31946,P31751,P27348 3 +Signaling by hippo 0.4448267341159674 0.7711403419654113 0.4406237508313111 1.0 0.7898832017028177 7 P42574,Q07157,P31946,Q13043 4 +Insulin receptor recycling 0.391465832450748 0.7681939201964436 0.4423719849929814 1.0 0.7898832017028177 11 Q9Y5K8 1 +Rhov gtpase cycle 0.3953867223350116 0.763778359171637 0.4449993352381101 1.0 0.7898832017028177 18 O00401,Q13153,Q03001,P60953,Q93008,Q00610,Q14155,Q16512,O43396 9 +Signaling by ntrks 0.3744216105599048 0.7635447974809525 0.4451385566260999 1.0 0.7898832017028177 33 Q8IV63,P31946,Q00535,P50570,P19174,P36507,P30154,Q16539,Q14738,P46109,P51452,Q06124,P28482,P40763 14 +Gastrin creb signalling pathway via pkc and mapk 0.4876197894322805 0.7590168108758933 0.4478425006031443 1.0 0.7909797659953883 5 P62993,P28482 2 +Traf3 dependent irf activation pathway 0.6311656504661631 0.7574601603297997 0.4487742254198348 1.0 0.7910190546139824 3 Q14258 1 +Advanced glycosylation endproduct receptor signaling 0.4236774639455195 0.7551798801048402 0.4501410591364461 1.0 0.7910190546139824 8 P28482,P09429 2 +Pentose phosphate pathway 0.4406932157994634 0.7517110220197756 0.4522248606251706 1.0 0.7913249789157744 7 P11413,O95336,P11908 3 +Aryl hydrocarbon receptor signalling 0.6294416243654891 0.7512531187000903 0.4525003376035243 1.0 0.7913249789157744 3 P08238,O00170 2 +Activation of the ap 1 family of transcription factors 0.6290758967998564 0.7499379847854124 0.4532920558272821 1.0 0.7915527105526662 3 P28482 1 +Phase ii conjugation of compounds 0.3792072815775033 0.7458815453663945 0.4557389742233646 1.0 0.7948270692226811 30 P21266,O43252,P78417,O60701,P48506,Q96IU4,P10768,P14550,P23526,Q16851,Q99707,P31153,Q9NUJ1,Q96KP4,Q9NZL9,Q8WUX2,O95861,P28161,P48507 19 +Telomere extension by telomerase 0.3857353410627729 0.7308318725546886 0.4648818529138452 1.0 0.8037425550995441 12 O00743,P20248,Q9BUR4,O15084 4 +Nuclear signaling by erbb4 0.6229448699255309 0.7279769658070229 0.4666276867155003 1.0 0.8037425550995441 3 P16949 1 +Fcgamma receptor fcgr dependent phagocytosis 0.3687478482297976 0.7263093398139534 0.4676491549771191 1.0 0.8037425550995441 33 P62993,O00401,P35579,Q13153,Q9UQB8,P07900,P19174,P60953,Q14185,P08238,P28482,Q16512,Q9NZQ3,Q7L576 14 +Nervous system development 0.4128340766515848 0.7257800499750705 0.4679736189069268 1.0 0.8037425550995441 222 O00560,P84098,P62861,Q00535,Q15369,P62333,P61254,P61247,P60953,Q7Z460,P62906,P50914,P46778,P36578,Q9BUF5,O75116,P25787,O00487,Q9BPU6,P27635,P28066,P62847,Q96S59,Q00169,P62241,Q13617,P28070,P61160,O00231,Q14155,Q96P70,P18621,P50570,Q9BVA1,O94973,P46776,Q13177,P68400,Q02750,Q02543,P25786,Q92796,P62829,P20618,Q16512,O15020,O00401,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P67870,Q9UNM6,P39019,Q9NR12,P11940,P48556,P28072,P25788,P15170,P51665,P04035,O15145,P05387,Q15418,P62899,P15880,Q14195,P62851,P62280,Q99460,P39023,P62266,P46783,Q13885,P62841,P62195,Q9BZI7,P62191,P62263,Q16539,P26373,P26038,P07947,O95782,P61313,O14818,O43242,P62854,P61289,P62269,P35241,P61513,P49721,P19784,P47914,P35579,Q15334,Q14185,Q06124,Q04637,Q9Y490,Q13153,P07900,P28074,P07737,P15311,P68371,P62993,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P19174,P36507,P49720,P08238,O75832,Q9HAU5,Q13464,P83731,P04350,P62753,P28482,Q00610,P35080,P17612,O95239,Q13200 136 +Metalloprotease dubs 0.434739182189249 0.7239209150021587 0.4691142888729114 1.0 0.8037425550995441 7 O95630,O00487 2 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3830317233203701 0.7232897427575066 0.4695018932216734 1.0 0.8037425550995441 11 O60566,Q9UJX5,O43684,Q9UJX4,Q16763 5 +Apc cdc20 mediated degradation of nek2a 0.3830317233203701 0.7232897427575066 0.4695018932216734 1.0 0.8037425550995441 11 O60566,Q9UJX5,O43684,Q9UJX4,Q16763 5 +Transcription of the hiv genome 0.3709074191536556 0.7232530563539696 0.4695244278711006 1.0 0.8037425550995441 32 P29083,Q15369,Q92759,P18615,P35269,P18074,O60942 7 +Rho gtpases activate iqgaps 0.382968179900475 0.7161273292228397 0.4739127300950698 1.0 0.807277812294298 12 P68371,P60953,P04350,P46940,Q9BUF5,Q13885 6 +Polymerase switching on the c strand of the telomere 0.3851842262846162 0.7101438713892607 0.4776149231289897 1.0 0.8095761231739607 16 P28340,P41440,P49005 3 +Adaptive immune system 0.3912496331183107 0.7098651829023915 0.4777877430364561 1.0 0.8095761231739607 197 P53992,Q15369,P62333,Q7Z6Z7,P60953,Q9BUF5,P25787,P47755,O00487,Q14999,Q13616,Q9H1A4,Q9Y6B6,P28066,P49427,Q10567,P61163,Q13617,P28070,Q99661,Q9C0C9,O95486,P29144,Q9Y4B6,P31751,P61086,P55786,Q05086,O95376,O95487,O95352,P50570,P30154,O94822,P52888,Q14204,Q9Y3I1,Q9H0B6,Q9BXS5,P25786,P22314,P20618,Q16512,O15111,O15020,Q14997,P61081,P55036,Q08209,Q15386,Q9UJX4,O43237,P60059,O75935,A0AVT1,Q13885,P62195,P52732,Q16763,P47756,P62191,Q5T4S7,Q92990,Q93034,P63104,O14818,P68036,O43242,O43318,P61289,P33176,P09429,P19474,P49721,Q8TBC4,Q13618,Q14203,Q06124,Q7Z7E8,Q9NZ32,Q13153,P28074,P68371,P62993,P31946,P43686,P60900,P25789,P41240,Q15008,Q13309,Q9Y6G9,O00221,P19174,Q15436,P49720,O75832,Q8IWV7,Q9UII4,Q9ULT8,P04350,Q04206,Q9UJX5,Q14738,Q00610,P17612,O95239,O94979,Q13200 109 +Signaling by interleukins 0.3118300024680837 0.6991137025524438 0.4844809758353143 1.0 0.8159103203692175 114 P62191,P62993,O00170,P43686,P62333,P60900,P25789,P60953,Q15008,P52564,Q16539,P25786,P78417,P20618,P25787,O00487,Q53EL6,O15111,P22681,Q00653,P63104,O14818,O43242,P28066,Q14997,Q13126,P55036,O43318,P61289,P49720,Q00169,P09429,P51452,O75832,P40763,P28070,P49721,Q8IV63,O15357,Q99439,Q06124,P28482,P17612,P17987,Q04206,Q9H3K6,P45985,P07900,P30154,Q9UHD2,Q14738,P46109,P28074,Q13501,P42574,P62195,Q13200 57 +Golgi cisternae pericentriolar stack reorganization 0.3783231872265836 0.6985227980369886 0.4848503054855926 1.0 0.8159103203692175 11 P14635,O95067 2 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.8337313432835844 0.6944885849369713 0.4873758570322364 1.0 0.8191686109731664 2 Q00534 1 +Parasite infection 0.3788856900558548 0.6865208006299279 0.4923847521129374 1.0 0.8236038573248893 24 Q9Y2A7,P62993,O00401,P35579,Q9UQB8,P61160,P60953,Q14185,O15145,P28482,Q9NZQ3,Q7L576 12 +Regulation of kit signaling 0.6109286354135441 0.6854343077049964 0.4930699010950716 1.0 0.8237586088006607 3 P62993,P22681 2 +Raf activation 0.3741141133043938 0.6844357656047699 0.4937000378949769 1.0 0.8238211916854957 10 Q9UQ13,Q13555,P31946,P30154,P36507,Q14738,Q02750 7 +Telomere c strand synthesis initiation 0.4671962407024033 0.6716139248325336 0.5018295111259801 1.0 0.8328862437745791 5 P49642,P49643 2 +Ikba variant leads to eda id 0.4947420197783495 0.6711503286370865 0.5021247679499359 1.0 0.8328862437745791 4 Q00653,O15111 2 +Sulfur amino acid metabolism 0.3730649326939963 0.6711444050017282 0.5021285412108614 1.0 0.8328862437745791 11 Q13126 1 +Chromosome maintenance 0.3000758178383351 0.669457214747591 0.5032038647339265 1.0 0.8336750559954207 48 P28340,P41440,P35244,Q9BUR4,Q9UER7,P49005,P49642,P18858,O15084 9 +Regulation of gene expression in beta cells 0.8232835820895563 0.6621446907596791 0.5078784967457359 1.0 0.8384217464092315 2 P31751 1 +Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3744119301234314 0.6599622700678379 0.509278041983233 1.0 0.8397348497706927 14 P49368,Q99832,P50991,P40227,P67870,P17987,P48643,P19784 8 +Constitutive signaling by overexpressed erbb2 0.4901327071781248 0.6525934042508204 0.5140184388626661 1.0 0.8462479376723493 4 P62993,P07900 2 +Phosphorylation of the apc c 0.3693381366578198 0.6519309951377882 0.5144456887288742 1.0 0.8462479376723493 11 Q9UJX5,P53350,Q9UJX4,P14635,Q16763 5 +Myoclonic epilepsy of lafora 0.8191044776119407 0.6493445019476085 0.5161157273028001 1.0 0.8469903907330485 2 P13807 1 +Rho gtpases activate rocks 0.3707189258455503 0.645915433345444 0.5183341240635779 1.0 0.8476287440569098 13 O75116 1 +Dna repair 0.304172723074476 0.6448796021115704 0.5190052113088026 1.0 0.8477288410331794 112 P41440,P18074,Q14258,Q92547,P49005,Q9UQ84,P35244,Q99504,Q04323,O60921,P29372,P18858,P28340,Q92759,P20248,P20585,P52701,P61201,Q8TAT6,Q7L5N1,Q13535,Q86WJ1,Q92905,Q6P6C2,Q07864,P27695 26 +Rna polymerase iii transcription initiation from type 1 promoter 0.3657834411928192 0.6337613799767152 0.5262365606736583 1.0 0.8529406111945347 11 Q9NW08,Q9BUI4,O14802 3 +Aggrephagy 0.3715771663219352 0.6333709989844797 0.5264913988524538 1.0 0.8529406111945347 18 P68371,P07900,P04350,Q9BUF5,Q13885,Q14204,O43237 7 +Activation of ampk downstream of nmdars 0.3626371016378905 0.625750576971816 0.5314785535401523 1.0 0.8587247762218388 10 P68371,Q9BUF5,P04350,Q13885 4 +Phosphorylation of emi1 0.5912212600776348 0.6172717131487332 0.5370555212914876 1.0 0.8634485823286818 3 P53350,P14635 2 +Signal attenuation 0.5911007780024423 0.6168617525435308 0.5373259163412301 1.0 0.8634485823286818 3 P28482 1 +Met activates rap1 and rac1 0.4530719433438621 0.6128403152111754 0.5399819309062557 1.0 0.8667146466047292 5 P46109,Q96N67 2 +Glycogen synthesis 0.4252709204193677 0.6065755341126027 0.5441326408509779 1.0 0.8703617615452925 6 P13807,P46976,P36871 3 +Glutathione conjugation 0.3622284320339294 0.5925545821498248 0.5534792820708447 1.0 0.8827469804707153 15 P10768,P14550,Q8WUX2,P48506,Q96KP4,P78417,P28161,P48507 8 +Nostrin mediated enos trafficking 0.7991044776119411 0.5892612292144864 0.5556860488574646 1.0 0.8827469804707153 2 P50570 1 +Factors involved in megakaryocyte development and platelet production 0.2844823934882448 0.5845991921604706 0.5588172510136895 1.0 0.8851714972578489 49 P47756,P68371,Q00535,Q9H0B6,Q9BUF5,Q96Q89,P47755,O60333,Q13572,Q96N67,P33176,Q99661,P04350,Q14185,Q9H4M9,Q13885,P17612,O95239,P52732 19 +Mrna decay by 3 to 5 exoribonuclease 0.3605744612432726 0.5841450681156233 0.5591227155340945 1.0 0.8851714972578489 15 Q9Y2L1,Q15477,Q96C86 3 +Growth hormone receptor signaling 0.4446646881219163 0.5786198334383191 0.5628457190910434 1.0 0.8900518197230379 5 P40763 1 +Alk mutants bind tkis 0.4157786503561506 0.5664155944497654 0.5711112962343345 1.0 0.8962514908207826 6 Q9HC35 1 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3658329486315998 0.5599985224721633 0.5754804455077636 1.0 0.8993635967495027 9 Q9UJX4,Q13309,Q16763,Q9UJX5 4 +Transferrin endocytosis and recycling 0.3523463635796444 0.5594545936312871 0.5758515115878111 1.0 0.8993635967495027 12 Q9Y5K8 1 +Ripk1 mediated regulated necrosis 0.3540529012499991 0.5560599685406605 0.5781698600196266 1.0 0.9006054057642159 14 O00560,P41440,Q14790,P07900,P49327,Q13546,Q16543 7 +Mapk3 erk1 activation 0.4654221976516519 0.5558203122408388 0.5783336982824165 1.0 0.9006054057642159 4 Q02750,Q06124 2 +Crmps in sema3a signaling 0.3963421345993461 0.5516743786372901 0.5811714670233488 1.0 0.9026014962708993 7 Q9BPU6 1 +Signaling by wnt in cancer 0.3794800733420669 0.5481330916609444 0.5836005199459242 1.0 0.9038940487950268 8 Q14738 1 +Kinesins 0.3539512859708237 0.5422122743265299 0.5876722805887395 1.0 0.9038940487950268 22 P68371,Q9H0B6,Q99661,P04350,Q9BUF5,P33176,Q96Q89,Q13885,P52732,O60333 10 +Polo like kinase mediated events 0.3939257821919872 0.5413233183481072 0.5882847507149662 1.0 0.9038940487950268 7 P14635,O95067 2 +Regulation of bach1 activity 0.5682293221857342 0.5407124863157835 0.5887057707687484 1.0 0.9038940487950268 3 Q13616,Q13309 2 +Prolactin receptor signaling 0.5682293221857324 0.5407124863157774 0.5887057707687526 1.0 0.9038940487950268 3 Q13616,Q06124 2 +Biological oxidations 0.2975570205106222 0.5352246685521446 0.5924945101400869 1.0 0.906649768652434 45 P21266,O00170,O43252,P78417,O60701,P48506,P07099,P11766,P08238,Q96IU4,O43488,P10768,P14550,P23526,Q16851,Q86WA6,P30837,Q99707,P31153,Q9NUJ1,Q96KP4,P51580,Q9NZL9,Q8WUX2,O95861,P28161,P48507 27 +Hiv transcription elongation 0.3494372241096043 0.5282260031649507 0.5973424834288106 1.0 0.9104233025943492 25 Q15369,Q92759,P18615,P35269,P18074 5 +Nephrin family interactions 0.3740420153431571 0.5241279553288254 0.6001895459185544 1.0 0.9132471109241586 8 P46940,O00401,Q9Y5K6 3 +Nuclear events stimulated by alk signaling in cancer 0.3444377406510275 0.5211560415462873 0.6022580737611756 1.0 0.9132471109241586 12 Q9HC35,Q00610,P33176,P62753,P28482,P40763 6 +Signaling by vegf 0.3397372983978913 0.5208370536051279 0.6024802882859377 1.0 0.9132471109241586 31 O75116,P31751,Q9UQB8 3 +Metabolism of cofactors 0.4298229184666746 0.5197954619840639 0.6032061426087845 1.0 0.9133289902938532 5 P00374,O75874 2 +Zbp1 dai mediated induction of type i ifns 0.3727766769350134 0.5185982534835348 0.6040409272621998 1.0 0.9133289902938532 8 Q00653,Q9UHD2,Q04206,O15111 4 +Clec7a inflammasome pathway 0.5611685106790586 0.5179322803562137 0.6045055187556438 1.0 0.9133289902938532 3 Q14790 1 +Processing of dna double strand break ends 0.3416210767910267 0.5120930643685675 0.6085858783331752 1.0 0.9159723761750086 29 O60921,Q9UQ84,P35244 3 +Activated tak1 mediates p38 mapk activation 0.4024760990902408 0.5116582012000357 0.6088902445802342 1.0 0.9159723761750086 6 O43318,Q16539 2 +Metabolic disorders of biological oxidation enzymes 0.4003279798033881 0.5029976839370056 0.6149659005187176 1.0 0.9159723761750086 6 P48506,P23526,P51580,P48507 4 +Apc c cdc20 mediated degradation of cyclin b 0.3373638383452163 0.5028342061679109 0.615080842033844 1.0 0.9159723761750086 10 Q9UJX4,P14635,Q16763,Q9UJX5 4 +Vegfr2 mediated vascular permeability 0.3389468273416224 0.5023254816340416 0.61543858761578 1.0 0.9159723761750086 11 P31751 1 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3532036825563426 0.50226557821301 0.6154807189550058 1.0 0.9159723761750086 9 Q93008,P28482,Q9UPN9 3 +Map3k8 tpl2 dependent mapk1 3 activation 0.3988203290609972 0.4969512652882079 0.6192234187048602 1.0 0.9205567401066904 6 Q13616,P45985,O15111 3 +Cytosolic sensors of pathogen associated dna 0.3440824214786414 0.4936016255860246 0.6215875525222749 1.0 0.9228571998694468 23 Q00653,Q9BUI4,O14802,Q04206,Q9UHD2,O15160,P19474,Q9NW08,P13010,O15111 10 +Intra golgi and retrograde golgi to er traffic 0.266031143621334 0.489331187122198 0.6246072448967737 1.0 0.925590693397138 92 P47756,P68371,P53621,Q8N6T3,Q9UID3,P52732,Q9H0B6,P20645,Q9BUF5,Q9UBF2,Q96Q89,P47755,O60333,P61923,P33176,Q99661,Q96JB2,P04350,Q14203,O43237,P24390,P53618,P48444,Q5VZE5,Q92538,P43034,O75935,Q9NZ32,Q14746,Q8TD16,O43264,Q13885,O60664,Q14204,P54920,Q15042 36 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.3434728337974399 0.4877456561484808 0.6257300083590045 1.0 0.9262669985293038 20 Q00653,Q9UII4,Q04206,Q13526,Q14790,P07900,Q9UHD2,P61086,Q14258,P08238,P09429,O15111 12 +Rho gtpase effectors 0.2991526990195289 0.4795538028727618 0.631544702186206 1.0 0.9290616385535798 125 P68371,P62993,P31946,Q9UQB8,P53350,Q7Z460,Q9HBM1,Q9H0B6,Q16539,Q99570,Q9BUF5,Q6P1K2,O75116,Q16512,P50748,Q9NZQ3,Q9Y6G9,O00401,Q14008,O60566,P27348,P63104,O14980,Q9HD26,O43684,P33176,Q2NKX8,Q99661,O43683,P35579,Q9H900,Q13526,Q13464,Q9P258,P04350,Q15334,P30307,O43237,P28482,Q16513,Q13153,P43034,P30154,O60610,Q15058,Q14738,O43264,Q13885,P35080,Q14204,P07737,Q15691 52 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5483519553980738 0.4775577396178534 0.6329650156188777 1.0 0.9290616385535798 3 P00374 1 +Amino acids regulate mtorc1 0.3375164899036859 0.4716785347250427 0.6371562608205792 1.0 0.9301591277025008 15 Q15382 1 +Gap junction trafficking and regulation 0.3351659018636518 0.4712547480099558 0.6374588265504779 1.0 0.9301591277025008 13 P68371,P50570,Q9BVA1,P04350,Q00610,Q9BUF5,Q13885,Q9UM54 8 +Negative regulation of met activity 0.3609248619710806 0.4678971120200067 0.6398581688456071 1.0 0.9301591277025008 8 P22681 1 +Runx3 regulates p14 arf 0.7558208955223924 0.4668987011995662 0.6405723545714057 1.0 0.9301591277025008 2 P42771 1 +Signaling by receptor tyrosine kinases 0.2901605085151252 0.4631468559287114 0.643259106188357 1.0 0.9301591277025008 118 P62993,P31946,P36543,Q00535,Q9UQB8,P60953,Q9Y5K8,Q93034,Q16539,P41240,Q99570,Q93050,O75116,Q16512,P22681,Q96N67,Q9Y487,P19174,P36507,Q96S59,P13984,P16949,P51452,P40763,P40818,Q8IV63,Q13464,Q13043,P31751,Q15334,Q14185,Q14155,Q96P70,Q06124,P61201,P28482,P50570,Q13153,P07900,P30154,O60610,P35269,Q14738,P46109,Q00610,O14654,P17612 47 +Protein ubiquitination 0.335884694014272 0.4624614824261951 0.6437504178775582 1.0 0.9301591277025008 26 Q96BN8,P68036,P49427,P61086,Q93008,P45974,Q5VTR2,P22314,Q14527,Q16763 10 +Arachidonic acid metabolism 0.4144846262724602 0.4614185677379951 0.6444983326084515 1.0 0.9302727750007762 5 Q8N8N7 1 +G1 s specific transcription 0.3290347226705887 0.456790265726186 0.6478218031305587 1.0 0.9312086120292068 11 P00374,Q99741,P31350,P04183 4 +Cd163 mediating an anti inflammatory response 0.7513432835820918 0.4549206983478431 0.649166291407411 1.0 0.9312086120292068 2 Q16539 1 +Vitamin b2 riboflavin metabolism 0.7495522388059725 0.4501683608188393 0.6525890479457408 1.0 0.9332291940787856 2 Q969G6 1 +G2 m dna damage checkpoint 0.3094706541550722 0.4449169791432008 0.656379751840362 1.0 0.9376748750928084 38 P31946,P35244,Q92547,O60921,P14635,Q9UQ84,Q13535 7 +Triglyceride metabolism 0.368612749099792 0.4373030218047654 0.6618916041581122 1.0 0.939764381797524 7 P17612,Q9HCL2,O60664 3 +Budding and maturation of hiv virion 0.3518091708313179 0.4303480280542384 0.6669424950651421 1.0 0.9417369745164336 8 Q8WUM4,O75351,Q9H9H4,Q9UN37 4 +Rho gtpases activate nadph oxidases 0.3660124600874127 0.4271212369823461 0.6692910254582887 1.0 0.9417369745164336 7 Q99570,P28482,Q16539 3 +Iron uptake and transport 0.3299271457224392 0.4245201221868726 0.6711865335248546 1.0 0.9417369745164336 19 Q13616,P36543,Q9Y487,P30519,Q9Y5K8,Q93050,Q86VP6,P21399 8 +Golgi to er retrograde transport 0.237204250823407 0.419797134803996 0.6746336581765031 1.0 0.9417369745164336 73 P47756,P68371,P53621,Q8N6T3,P52732,Q9H0B6,Q9BUF5,Q9UBF2,Q96Q89,P47755,O60333,P61923,P33176,Q99661,P04350,Q14203,O43237,P24390,P53618,P48444,Q9NZ32,Q92538,P43034,O75935,Q8TD16,O43264,Q13885,Q14204,P54920,Q15042 30 +Condensation of prophase chromosomes 0.3211888406195355 0.4151060169917865 0.678064294889789 1.0 0.9417369745164336 12 Q6IBW4,Q01105,P42695,O95347,Q9NTJ3,P14635 6 +Regulation of mecp2 expression and activity 0.3317487213593394 0.4100742186266888 0.6817515043104818 1.0 0.9417369745164336 9 Q9HCE1,Q13555,P42858 3 +Activated ntrk2 signals through frs2 and frs3 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Frs mediated fgfr4 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Signaling by flt3 itd and tkd mutants 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Stat5 activation downstream of flt3 itd mutants 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Pi 3k cascade fgfr4 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Frs mediated fgfr3 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Stat5 activation 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Tie2 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Pi 3k cascade fgfr3 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Pi 3k cascade fgfr1 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Frs mediated fgfr2 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Frs mediated fgfr1 signaling 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Pi 3k cascade fgfr2 0.7325373134328397 0.4061704608792585 0.6846173566604405 1.0 0.9417369745164336 2 Q06124 1 +Interleukin 15 signaling 0.7325373134328399 0.4061704608792582 0.6846173566604408 1.0 0.9417369745164336 2 P40763 1 +Interleukin receptor shc signaling 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 0.9417369745164336 2 O15357 1 +Erythropoietin activates ras 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 0.9417369745164336 2 P46109 1 +Signaling by fgfr4 in disease 0.7325373134328386 0.4061704608792555 0.6846173566604428 1.0 0.9417369745164336 2 P19174 1 +Grb2 sos provides linkage to mapk signaling for integrins 0.7325373134328385 0.4061704608792543 0.6846173566604437 1.0 0.9417369745164336 2 Q9Y490 1 +Signaling by tgfb family members 0.3259177837169412 0.4054682557585204 0.6851333477569619 1.0 0.9417369745164336 23 O14980,Q7Z3T8,P61081,O75909,Q93008,Q9Y5K5,P28482,Q8TEW0,Q9UPN9,P22681 10 +Hdl clearance 0.7319402985074672 0.4046655697359554 0.6857233537266558 1.0 0.9417369745164336 2 Q8WTV0 1 +Tnfr1 induced nfkappab signaling pathway 0.3281065558263944 0.395255606000748 0.6926542588346807 1.0 0.9451091431814742 9 Q12933,Q6GQQ9,P98170,O43318,Q13546,O15111 6 +Gpvi mediated activation cascade 0.3957781537580441 0.3940646240803109 0.6935333280900027 1.0 0.9451091431814742 5 Q06124 1 +Platelet aggregation plug formation 0.4183558282947198 0.3876940691865091 0.6982424452886895 1.0 0.9487360693560885 4 Q9Y490,P41240 2 +Integrin signaling 0.4183558282947198 0.3876940691865091 0.6982424452886895 1.0 0.9487360693560885 4 Q9Y490,P41240 2 +Recycling pathway of l1 0.3217246563195954 0.3862985319682986 0.6992755876083883 1.0 0.9492119792731052 23 O94973,P68371,P50570,Q9BVA1,O95239,P04350,Q00610,Q9BUF5,P26038,Q13885,P35241,P28482,Q15418,P15311 14 +Synthesis of pips at the golgi membrane 0.3240558877504677 0.3790837031056302 0.704625707780099 1.0 0.9518267578370628 9 Q08AM6 1 +Phenylalanine and tyrosine metabolism 0.3910965043322421 0.3779404062413246 0.7054748649279781 1.0 0.9520486041261064 5 P09417,P61457,P16930,Q7L266 4 +Death receptor signalling 0.3139736755242464 0.377006855917087 0.7061685099374184 1.0 0.9520603577235806 30 Q14790,Q96BN8,Q9H8V3,O43318,Q14155,Q13501,P49327,P42574,O15111 9 +Sting mediated induction of host immune responses 0.3523532233142765 0.375379114638552 0.7073785352835769 1.0 0.952767600817996 7 P19474 1 +Signaling by tgf beta receptor complex 0.3162964512632463 0.3619216544220508 0.7174105774706572 1.0 0.9634789397915106 21 O14980,P61081,O75909,Q93008,Q9Y5K5,P28482,Q8TEW0,Q9UPN9,P22681 9 +Interferon gamma signaling 0.3086191807180783 0.3563376786156458 0.7215876952816975 1.0 0.9656994547525032 13 P19474,P29372,Q14258 3 +Signaling by fgfr 0.3148338323938365 0.3554065662576797 0.7222850303937696 1.0 0.9656994547525032 22 P19174,P35269,Q06124,P22681 4 +Signaling by fgfr2 0.3148338323938365 0.3554065662576797 0.7222850303937696 1.0 0.9656994547525032 22 P19174,P35269,Q06124,P22681 4 +Regulation of cholesterol biosynthesis by srebp srebf 0.3120852912947247 0.3527137827480677 0.7243030255064611 1.0 0.9656994547525032 27 O95486,Q9HCL2,P53992,Q15126,O95487,Q9Y6B6,Q15436,P62826,Q13907,P04035,Q01581,P48449,P49327,Q15648,Q86X55,P53602,O95749 17 +Synthesis of pips at the er membrane 0.40738831662753 0.3523338074866133 0.7245879369131414 1.0 0.9656994547525032 4 P42356 1 +Protein methylation 0.3459764082360731 0.3522884289936123 0.7246219649689647 1.0 0.9656994547525032 7 O60678,P13639 2 +Senescence associated secretory phenotype sasp 0.3104410758215297 0.3372915791681347 0.7358971070226654 1.0 0.9731722785146052 21 P42771,Q00534,P20248,P28482,P40763,Q16763 6 +Nf kb is activated and signals survival 0.7032835820895564 0.3357387741112909 0.7370678637739247 1.0 0.9731722785146052 2 Q13501 1 +P75ntr signals via nf kb 0.7032835820895564 0.3357387741112909 0.7370678637739247 1.0 0.9731722785146052 2 Q13501 1 +Interleukin 1 processing 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.9731722785146052 2 Q00653 1 +Signaling by notch3 0.3409177912388668 0.3344841472179642 0.7380142514160521 1.0 0.9731722785146052 7 P67809 1 +Abortive elongation of hiv 1 transcript in the absence of tat 0.304169844453122 0.3332348398995325 0.7389570211236551 1.0 0.9731722785146052 14 P18615,P35269 2 +Endosomal sorting complex required for transport escrt 0.3262559808612328 0.3328077550844091 0.7392794039277633 1.0 0.9731722785146052 8 Q8WUX9,Q9H9H4,Q99816,O75351,Q9UN37,Q92783,Q9NZZ3 7 +Regulated necrosis 0.3086256891230531 0.3327395636965684 0.739330882094549 1.0 0.9731722785146052 19 P49327,P41440,P09429,Q14790 4 +Synthesis of pyrophosphates in the cytosol 0.6994029850746337 0.3269243170271285 0.7437251284632562 1.0 0.975352148226435 2 Q13572 1 +Downregulation of tgf beta receptor signaling 0.352508571708502 0.3261869710798545 0.7442828983645862 1.0 0.975352148226435 6 O14980,Q9Y5K5 2 +Fcgr3a mediated il10 synthesis 0.3377215481162315 0.3234767014592216 0.7463342494325467 1.0 0.9767997841272152 7 P17612,P19174 2 +Pyroptosis 0.3740373751444173 0.3219178255061535 0.7475149486419801 1.0 0.9767997841272152 5 P09429 1 +Sema3a pak dependent axon repulsion 0.3227570809363942 0.3204307082875769 0.7486418498851228 1.0 0.9767997841272152 8 P07900,Q16512,P08238,Q13153 4 +Heme signaling 0.3459628267332579 0.3047516922038197 0.760555276359371 1.0 0.9869096062689734 6 Q96EB6,Q15648,O14980 3 +Tbc rabgaps 0.2888353167194021 0.3005192260223375 0.7637811335276579 1.0 0.9869096062689734 10 Q9UJY4 1 +Trif mediated programmed cell death 0.686865671641798 0.2993372300938526 0.7646827505807015 1.0 0.9869096062689734 2 Q14790 1 +Tlr3 mediated ticam1 dependent programmed cell death 0.686865671641798 0.2993372300938526 0.7646827505807015 1.0 0.9869096062689734 2 Q14790 1 +Semaphorin interactions 0.2997153269921973 0.2972703116696246 0.7662601455448357 1.0 0.9869871711072786 26 O75116,Q9BPU6 2 +Rhobtb3 atpase cycle 0.4832066488090233 0.2957086893996692 0.7674525606376768 1.0 0.9869871711072786 3 O60664 1 +Nr1h2 and nr1h3 mediated signaling 0.3623931822595102 0.2863171676830989 0.7746352103702061 1.0 0.9900305346585012 5 P49327 1 +Dna damage recognition in gg ner 0.289815137795832 0.2753524833265462 0.783045446311913 1.0 0.995821747825763 15 Q16531,Q9UGN5,Q13619,Q92905,Q99627,Q13620,P09874,P61201,Q7L5N1,P54727 10 +Deadenylation of mrna 0.2908956316184272 0.2714447228485567 0.786049008867578 1.0 0.996905221100304 17 O95628,P06730,Q9UIV1,Q5TAX3,Q04637,Q14240,A5YKK6 7 +Oas antiviral response 0.4712498903908045 0.2672914754824303 0.78924474965872 1.0 0.9990230620178584 3 P61221 1 +Metabolism of ingested semet sec mesec into h2se 0.6704477611940343 0.2653320174684166 0.7907537017597797 1.0 0.9992251322237216 2 P23526 1 +Ca2 pathway 0.2907137659358972 0.2596590124696589 0.7951268116903705 1.0 1.0 9 Q08209 1 +Metabolism of water soluble vitamins and cofactors 0.2603626755912531 0.2497856609618473 0.8027531092184439 1.0 1.0 42 P41440,Q99707,O96007,P00374,Q9NVE7,P49327,P78417,P43490 8 +Hiv elongation arrest and recovery 0.2868557870136155 0.2472859870831376 0.8046869027807544 1.0 1.0 22 Q15369,P18615,Q8IXH7,P35269,O75909,Q9Y5B9 6 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.2989892739672595 0.2433468156202858 0.8077367405046192 1.0 1.0 8 Q9UJX4,Q16763,Q9UJX5 3 +Cytosolic sulfonation of small molecules 0.3682451459431387 0.2405852253230138 0.8098766023722594 1.0 1.0 4 Q96IU4,O95861 2 +Rhobtb1 gtpase cycle 0.2840508736507768 0.2404772602247632 0.8099602898215967 1.0 1.0 20 O75116,Q5VTR2,O43396 3 +Rip mediated nfkb activation via zbp1 0.3083285759725694 0.2317218024532799 0.816754096320822 1.0 1.0 7 Q00653,Q04206,O15111 3 +Rhob gtpase cycle 0.281081299589154 0.2291963149528848 0.8187163366006003 1.0 1.0 21 P41440,Q9H8V3,O75116,Q16512,Q92974,Q16513 6 +Transcriptional regulation by tp53 0.2734541949304503 0.22477636560018 0.8221532531356259 1.0 1.0 138 P31946,O75880,Q00535,Q15369,Q5RI15,Q8IXH7,Q16539,P42771,Q92696,P18074,Q9UER7,Q92547,O96017,Q9UQ84,P11413,P35244,P27348,O60921,Q15382,P67870,Q99873,P19784,O14965,Q92759,P31751,P24386,P55212,Q9UIV1,P20248,P30307,P49327,Q9HCE1,P14854,Q13535,O95628,P30154,P18615,P35269,O14744,P14635 40 +Srp dependent cotranslational protein targeting to membrane 0.2299646318270783 0.2201031199486508 0.8257908450234541 1.0 1.0 93 P46776,P84098,P62750,P62861,P60866,P62917,P62906,P61254,P61247,P50914,P46778,O76094,P62081,Q9UHB9,P32969,P62701,P27635,P62847,P08708,P62854,P42766,P39019,P62269,P61513,P47914,P83731,P05387,P62753,P18621,P60059,P62899,P15880,P39023,P62266,P46783,P62841 36 +Activation of gene expression by srebf srebp 0.2776172445938915 0.2198899886766432 0.8259568333858713 1.0 1.0 20 Q15126,P48449,P49327,Q15648,P53602 5 +Deadenylation dependent mrna decay 0.2580633967985964 0.2169776559319785 0.8282257581202404 1.0 1.0 40 Q9Y2L1,O95628,Q6P2E9,Q14240,Q96C86,P26196,P06730,Q9Y450,Q5TAX3,Q92600,Q9UIV1,Q15477,Q04637,Q969T7,Q86TB9,Q96F86,A5YKK6 17 +Trna processing 0.2026494711972315 0.2163522401324261 0.8287131914344859 1.0 1.0 67 Q9UJA5,O15091,O75818,Q2VPK5,Q7Z4G4,P57081 6 +Tp53 regulates transcription of dna repair genes 0.268387223111649 0.2162528476515885 0.8287906615082665 1.0 1.0 35 Q15369,Q92759,P18615,P35269,P18074,Q13535 6 +Metabolism of vitamins and cofactors 0.2198341050102076 0.2123014837799117 0.8318718379266605 1.0 1.0 51 P41440,Q99707,O96007,P00374,Q9NVE7,P49327,P78417,P43490 8 +Met promotes cell motility 0.3103028203506939 0.2020559300326122 0.8398729999473469 1.0 1.0 6 P46109,Q96N67 2 +Triglyceride catabolism 0.3055009150029657 0.1901684423142222 0.8491771392341478 1.0 1.0 6 P17612,Q8WTS1,O60664 3 +Developmental biology 0.3603967491545096 0.1882824026646919 0.8506552792941937 1.0 1.0 270 O00560,P84098,Q03164,P62861,Q00535,Q15369,P62333,P61254,P61247,P60953,Q7Z460,P52564,P50914,P62906,P46778,P36578,Q9BUF5,O75116,P25787,Q86X55,O00487,Q9BPU6,P27635,P28066,P62847,P11802,Q96S59,P62241,Q00169,Q15648,Q13617,Q96EK7,P28070,P61160,O00231,P31751,O00330,Q14155,Q96P70,P18621,P50570,Q9BVA1,Q9NPJ6,O94973,P46776,O60271,Q13177,P68400,Q02750,Q02543,P25786,Q92796,P62829,P20618,Q16512,O15020,O00401,P32969,P62701,P62495,Q14997,P08708,P55036,P42766,P67870,Q9UNM6,P39019,Q9ULK4,Q9NR12,P11940,P48556,P28072,P25788,P15170,P51665,P07384,P04035,O15145,P05387,Q15418,P62899,P15880,Q14195,P62851,P62280,P39023,P62266,P46783,Q13885,P62841,P62195,P62191,Q16539,O14818,O43242,P62854,P61289,P62269,P35241,P61513,P40763,P49721,P19784,P47914,P35579,Q15334,Q14185,Q06124,Q04637,Q9Y490,Q13153,P07900,Q9Y2X0,P28074,P07737,P15311,P68371,P62993,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,Q92600,P62081,P19174,P36507,P49720,P08238,O75832,Q9HAU5,Q13464,P83731,P04350,P62753,P28482,Q04206,Q00610,P35080,P17612,O95239,Q13200 144 +Eph ephrin signaling 0.2624705494150632 0.1826157826792096 0.8550994998027803 1.0 1.0 32 O75116,Q14155 2 +Assembly of the hiv virion 0.6232835820895579 0.1817255388220909 0.8557981225986069 1.0 1.0 2 Q9H9H4 1 +Phenylalanine metabolism 0.4269931322782969 0.1775463602639564 0.85907925338836 1.0 1.0 3 P61457,Q7L266 2 +Atf4 activates genes in response to endoplasmic reticulum stress 0.2521855692649848 0.1770671994198806 0.8594556058579601 1.0 1.0 12 Q9Y2L1 1 +Ikk complex recruitment mediated by rip1 0.3180231250912053 0.172704276225138 0.8628838823623914 1.0 1.0 5 O15111 1 +Cdc42 gtpase cycle 0.2566751638513901 0.172520694072896 0.8630281937493587 1.0 1.0 34 Q16512,Q96N67,Q14155,Q9UQB8 4 +Enos activation 0.3357228195937758 0.1670244394259635 0.8673508191518069 1.0 1.0 4 P07900,O75608,O95865 3 +Signaling by fgfr2 in disease 0.245784174372703 0.1663929960469408 0.867847685468591 1.0 1.0 11 P62993,P19174,P35269 3 +Sumoylation of immune response proteins 0.4197357840824406 0.1652380754429367 0.8687565972841005 1.0 1.0 3 Q00653 1 +Mitophagy 0.246317237415431 0.1589298790347795 0.8737241198095422 1.0 1.0 13 P67870,P19784 2 +Golgi associated vesicle biogenesis 0.2558384773590404 0.1588087838802881 0.8738195281071623 1.0 1.0 30 O43747,O60749,P50570,P54920,Q14677,O00203,Q14789,Q9BXS5,Q9Y5X3,Q10567,Q00610,Q8NC96,Q01968,O00443,P49407 15 +Mitotic metaphase and anaphase 0.2601970713436886 0.157319139459665 0.8749933369666556 1.0 1.0 141 P68371,P62191,P63151,P43686,P60900,P53350,Q7Z460,Q9HBM1,P25789,Q15008,O95067,Q9BUF5,P25786,Q6P1K2,P25787,P50748,P20618,O00487,Q9Y6G9,Q14008,O60566,O14818,O14980,O43242,P28066,Q14997,O43684,P55036,P49720,P61289,O75832,P28070,P49721,Q99661,Q2NKX8,O43683,Q9H900,Q92973,Q9P258,Q8IXJ6,P04350,Q9UJX4,Q92674,O43237,Q29RF7,Q7Z5K2,P43034,Q99986,P30154,Q14738,P14635,P28074,O43264,Q13885,Q16763,Q14204,Q15691,P62195,Q13200 59 +Ticam1 rip1 mediated ikk complex recruitment 0.3294448489119783 0.1549704641149971 0.8768446021896559 1.0 1.0 4 O15111 1 +Transcriptional regulation by ventx 0.2432270559100879 0.1484337274681971 0.8820004842073512 1.0 1.0 14 Q04206,Q9UJX5,P42771,Q9UJX4,Q9HCE1,Q16763 6 +Metabolism of steroids 0.2122686025245076 0.147801233748172 0.8824996356433965 1.0 1.0 49 Q15392,Q9BWD1,Q9HCL2,Q15126,Q9Y6B6,P22059,Q9BZF3,P48449,P49327,Q15648,P53602 11 +Hdr through mmej alt nhej 0.2604665071770335 0.1467485521689741 0.8833304943295373 1.0 1.0 8 Q9UGN5,P49916,P18887,O60934,P09874,P39748,Q92878 7 +Rho gtpases activate ktn1 0.2589712918660227 0.1437375823692686 0.885707692899016 1.0 1.0 8 P84095,P61586,P60953,Q07866,Q9H0B6,P33176,P63000 7 +Constitutive signaling by aberrant pi3k in cancer 0.282189840728653 0.139358639945982 0.8891667539160402 1.0 1.0 6 P62993,Q06124 2 +Formation of tc ner pre incision complex 0.2485088075486597 0.1382226704011851 0.8900644386773915 1.0 1.0 25 Q13619,Q7L5N1,Q92905,Q92759,P18074,P61201,Q99627 7 +Nef mediated downregulation of mhc class i complex cell surface expression 0.3003430412203577 0.1378453226619529 0.8903626639344053 1.0 1.0 5 Q10567,Q9BXS5 2 +Cholesterol biosynthesis 0.2447869551540906 0.1378024689477487 0.8903965330398367 1.0 1.0 19 Q9BWD1,Q15392,P48449,Q15126 4 +Met activates ptpn11 0.4013896487935557 0.1371806854086353 0.8908879773803089 1.0 1.0 3 Q06124 1 +Rhobtb gtpase cycle 0.2450495683905058 0.1327119370429777 0.894421201981445 1.0 1.0 30 Q8IYB3,Q99832,Q13464,Q8N684,P07900,Q13618,P78371,Q16543,P40227,Q96DH6,P08238,Q5VTR2,P61201,O75116,Q9UM54,P12814,O43396 17 +Metabolism of folate and pterines 0.239331414437945 0.1307571863366083 0.8959673924800979 1.0 1.0 9 P41440 1 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.227674204139608 0.129124134963418 0.8972594249329542 1.0 1.0 11 Q9Y2L1 1 +Rac1 gtpase cycle 0.2105435399552512 0.1218922832184021 0.9029843271555742 1.0 1.0 47 Q96N67,Q9UQB8,Q9H8V3,Q14185,Q14155,Q16512 6 +Formation of rna pol ii elongation complex 0.2385984095594475 0.1216552398631145 0.9031720632603376 1.0 1.0 32 Q15369,Q92759,P18615,P35269,P18074 5 +Clathrin mediated endocytosis 0.1932961850468114 0.1212169556124589 0.903519194510348 1.0 1.0 52 P62993,O00401,Q8N6T3,Q7L5N1,P50570,Q92905,Q96D71,P20645,Q8NC96,P49407,Q00610,P61201,Q01968,Q9NVZ3,Q14C86,O00443,Q99627,P22681 18 +Rab regulation of trafficking 0.2366067687129872 0.1175978643149013 0.906386297234699 1.0 1.0 32 Q7Z392,P31751,P24386,Q9UJY4,Q8TC07,Q15042 6 +Post translational protein modification 0.19436553216623 0.1158114715643619 0.9078019587018766 1.0 1.0 405 Q15369,P85037,Q9BUF5,P51784,P25787,O95394,P47755,O00487,Q14999,O60725,Q9Y6B6,P28066,P49427,Q96RU2,Q86VP6,Q13617,P28070,Q99627,O15084,Q9UPT9,Q5TAQ9,P61086,P24386,O60678,P13639,P14735,O95487,P24390,P53618,P26572,P48444,Q96BN8,Q93008,Q14204,Q14527,P34949,Q9Y3I1,Q9UER7,Q9UBF2,P25786,P22314,P20618,O43505,O15020,O00743,Q14997,P61923,Q06210,P61081,P55036,P26358,P45974,P40818,Q5H9R7,Q96JB2,O43237,Q9UIS9,Q16186,P15880,Q9BV10,Q92734,O94966,O75935,A0AVT1,Q13885,P62195,Q16763,P47756,P62191,Q8N6T3,Q96K76,Q93034,P42771,Q14694,Q92696,Q14258,O60826,Q14166,Q13619,O14818,Q9NR45,O15027,Q9UBT2,P68036,Q04323,O43242,O43318,P61289,P61962,P49721,P49407,Q8TBC4,Q13618,Q6GQQ9,P20248,O60493,Q13564,Q86UV5,Q92538,Q9NZ32,Q92905,Q9BQC3,Q5VTR2,P28074,O95630,P60900,Q15008,Q96IJ6,Q13309,Q00653,P49720,Q96FW1,Q9Y5A7,O14965,P04350,P63241,P61201,Q15293,Q7L5N1,Q14746,P53602,Q13200 122 +Fbxw7 mutants and notch1 in cancer 0.5680597014925446 0.1109810134507633 0.9116314027841672 1.0 1.0 2 Q13616 1 +Sensory processing of sound 0.2280385380595017 0.1098497721052761 0.9125285174260572 1.0 1.0 18 P47756,P35579,Q6IBS0,P35241,P15311,P47755 6 +Regulation of pten localization 0.5665671641791117 0.1094630893345811 0.9128351962481092 1.0 1.0 2 Q93009 1 +Translocation of slc2a4 glut4 to the plasma membrane 0.2223622707102954 0.1094006211712307 0.9128847410833614 1.0 1.0 40 P35579,P31946,P27348,P63104,O60343,Q86X10,P31751,P04350,Q96KP1,Q8TAG9,Q9BUF5,Q13885 12 +Dex h box helicases activate type i ifn and inflammatory cytokines production 0.2999017669497051 0.1075690528306528 0.9143375467739356 1.0 1.0 4 Q00653 1 +Perk regulates gene expression 0.2200668991263252 0.1072189742219003 0.9146152629467176 1.0 1.0 14 Q9Y2L1 1 +Infectious disease 0.1992528314520046 0.1051816829032868 0.9162316450174262 1.0 1.0 359 O00410,P84098,P62861,Q9UQB8,Q15369,P62906,P62333,P61254,Q8IXH7,P61247,P60953,P52564,Q99570,P50914,P46778,Q9BUF5,P36578,O75116,P25787,Q13546,O00487,P62847,P27635,P28066,O60942,Q96SB4,P28070,P18858,P78362,P13639,P18621,P26572,P45985,P35269,Q14204,P46776,O00629,Q9BXS5,Q9UER7,P25786,P20618,P22681,O00401,P32969,P62701,Q14997,P08708,P55036,P42766,P39748,P39019,Q92759,P05387,O43237,P62899,P15880,P43487,P18615,P39023,P62266,P46783,Q13885,P62841,P62195,P62191,Q93034,Q16539,P18074,Q9NZQ3,O14818,O14980,O43242,P62854,P61289,P12268,P62269,P61513,P49721,P47914,P35579,Q13618,Q14185,Q9Y5B9,P07900,O75909,O75351,P28074,P68371,P29083,P60866,P62993,P62750,P62917,P60900,P43686,P25789,Q15008,Q9Y6G9,Q00653,P62081,P19174,P36507,P49720,P13984,P08238,O75832,Q99873,Q13464,P83731,P04350,P07437,P20839,P62753,P28482,Q04206,Q9UHD2,Q9H9H4,Q00610,P17612,P13010,P00558,Q13200 122 +Irf3 mediated induction of type i ifn 0.2603108188882182 0.1020908547325484 0.9186845599528252 1.0 1.0 6 Q9UJV9,Q9UHD2,P78527,P12956,P13010 5 +Cellular responses to stimuli 0.2197219677858193 0.101025830328602 0.9195299554353278 1.0 1.0 341 P84098,P62861,P36543,Q15369,P62906,P62333,P61254,P61247,P52564,P50914,P46778,Q9BUF5,P36578,Q92598,P25787,Q86X55,P47755,O00487,Q14999,Q13616,Q9H1A4,P35244,P62847,P27635,P28066,P11802,P62241,Q15382,P27694,Q15648,Q13617,P28070,P14854,P18621,Q13535,Q96B36,P51858,P45985,P30519,Q14204,P46776,O75880,Q9Y5K8,P25786,P20618,P32969,P35611,P62701,Q14997,P08708,Q06210,P55036,P42766,P39019,P67870,Q9UL15,Q9UJX4,P05387,O43237,Q9HCE1,P62899,P15880,Q9Y2L1,P05198,O75935,P39023,Q00534,P62266,P46783,Q13885,P62841,P62195,Q16763,P47756,P62191,Q8N6T3,Q5RI15,Q16539,P42771,Q99615,O14818,O14980,O43242,P62854,P61289,P08243,P62269,P31689,P61513,P40763,P49721,P19784,Q96EB6,P47914,Q13618,Q14203,P20248,Q9Y490,Q92616,Q9NZ32,P07900,Q9GZT9,P28074,O75182,P68371,P60866,P62750,P62917,P60900,P43686,P53004,P25789,Q15008,Q13309,Q9Y6G9,P62081,P49720,P08238,O75832,P30043,Q13555,P83731,P04350,P62753,P28482,Q04206,Q9UJX5,O60884,O95070,Q0VDF9,O94979,Q13200 132 +Rna polymerase ii transcription 0.184803392744152 0.0994096750989963 0.9208130011987188 1.0 1.0 334 Q03164,Q00535,Q15369,Q8IXH7,P25787,Q9UQ84,O00487,P35244,P28066,P11802,O60921,O60942,Q15382,Q92620,Q15648,P28070,Q9HCL2,P31751,P24386,P55212,P14854,Q13535,Q9H814,P30154,P35269,Q93008,O75880,Q9UER7,P25786,P20618,O96017,P31350,Q05519,Q14997,P55036,P67870,Q8IYB3,Q92759,Q9UJX4,Q9UIV1,Q9HCE1,O95628,P18615,P42858,Q00534,P62195,Q16763,P62191,Q6P9B9,Q5RI15,Q16539,P42771,Q92696,P18074,Q96P16,Q96HW7,Q14353,Q9UPN9,P27348,P63104,O14818,O43242,P61289,P49721,P19784,Q96EB6,P20248,P49327,Q06124,Q9Y2X0,P28074,P14635,O75182,P29083,P31946,P60900,Q15008,Q6PL18,Q92547,Q13309,P11413,P49720,Q99873,P10589,O14965,P30307,P51003,P28482,O14744,Q13200 90 +Sensory processing of sound by outer hair cells of the cochlea 0.2109215089706481 0.0974428726562621 0.922374699245142 1.0 1.0 13 P35241,Q6IBS0,P35579,P15311 4 +Cell cycle 0.2840756041680228 0.0952827935020111 0.9240902092639344 1.0 1.0 313 Q7Z460,P25205,Q9BT25,Q9BUF5,Q6P1K2,P25787,P50748,Q9UQ84,O00487,P35244,O60566,Q9UH99,P28066,P11802,O60921,Q96CW5,P28070,P18858,O15084,Q99661,Q01105,Q9UBD5,Q9H900,Q9P258,Q9Y570,P31751,P04183,Q13535,P43034,P30154,Q14204,Q9BRT9,Q9BPX3,Q9HBM1,Q9BUR4,O95067,Q9UER7,P25786,P20618,O96017,P49005,P31350,O00743,Q99996,Q14997,P55036,P39748,P67870,Q2NKX8,P28340,Q5H9R7,Q7Z4H7,Q9BSJ2,Q9UJX4,Q9NTJ3,O43237,Q9UIS9,Q9HC35,O75935,Q07864,Q00534,Q15021,Q15003,Q13885,Q15691,P62195,Q16763,P62191,P41440,P42771,Q14008,P27348,P63104,O14818,O14980,O43242,O43684,P61289,P49642,P49721,P19784,Q92973,Q8IXJ6,Q14203,P00374,P20248,Q7Z5K2,Q99986,P07900,O95347,P28074,O43264,P14635,P68371,P31946,P63151,P49643,P60900,P43686,P35251,P53350,P42695,P25789,Q15008,Q92547,Q13309,P49720,O14965,P04350,P07437,P30307,P28482,Q6IBW4,Q14738,Q13200 115 +Cell cycle mitotic 0.3009063288538984 0.0943476058372886 0.924833034549872 1.0 1.0 262 Q7Z460,P25205,Q9BT25,Q9BUF5,Q6P1K2,P25787,P50748,O00487,O60566,P35244,P28066,P11802,Q96CW5,P28070,P18858,Q99661,Q01105,Q9UBD5,Q9H900,Q9P258,Q9Y570,P31751,P04183,P43034,P30154,Q14204,Q9BRT9,Q9BPX3,Q9HBM1,O95067,P25786,P20618,P49005,P31350,Q99996,Q14997,P55036,P39748,P67870,Q2NKX8,P28340,Q7Z4H7,Q9BSJ2,Q9UJX4,Q9NTJ3,O43237,Q9UIS9,Q9HC35,O75935,Q07864,Q00534,Q15021,Q15003,Q13885,Q15691,P62195,Q16763,P62191,P41440,P42771,Q14008,O14818,O14980,O43242,O43684,P61289,P49642,P49721,P19784,Q92973,Q8IXJ6,Q14203,P00374,P20248,Q7Z5K2,Q99986,P07900,O95347,P28074,O43264,P14635,P68371,P63151,P49643,P43686,P35251,P60900,P53350,P25789,P42695,Q15008,Q13309,P49720,O14965,P04350,P07437,P30307,P28482,Q6IBW4,Q14738,Q13200 101 +Ovarian tumor domain proteases 0.1984921563622755 0.0906896255320029 0.9277392142864852 1.0 1.0 10 Q14258 1 +Innate immune system 0.2275952770729782 0.0897327924759806 0.9284995564214162 1.0 1.0 292 O00560,P36543,Q9UQB8,P62333,P60953,Q7Z6Z7,P52564,P61020,P50395,Q99570,P46940,Q9NW08,P25787,Q13546,P47755,Q7L576,O00487,O75874,P09972,P14618,P28066,P49427,Q86VP6,P28070,P61086,P13639,O95352,P46976,P53618,P50570,P45985,P30519,P30154,Q14204,Q9NQR4,Q9Y5K8,Q9BXS5,P25786,P22392,P20618,Q16512,O15111,O00401,P04075,Q9Y487,Q14997,P61081,P55036,P67870,Q08209,Q8IV63,Q14790,Q99439,P07741,P00491,O60610,O15160,P63172,P62195,P62191,Q5T4S7,Q16539,Q14258,Q9NZQ3,Q9Y376,Q9BUI4,O14818,O43242,P17858,O43318,P12268,P61289,O75165,P09429,P51452,P19474,P49721,P35579,Q8TBC4,Q14185,Q06124,Q9UNP9,Q9NZ32,Q13153,P07900,P04080,P28074,O00764,P18669,P68371,P62993,P43686,P60900,P25789,Q15008,Q93050,Q9Y6G9,Q00653,O14802,P09960,P19174,P49720,P53396,P08238,O75832,Q9UII4,Q13526,Q13464,P36871,P07437,P20839,P28482,Q8IUR7,Q5T9A4,Q04206,Q9UQ80,Q9UHD2,Q14738,P06737,P17612,P13010,Q13200 122 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.1991772321982873 0.0865525355419799 0.9310271953949544 1.0 1.0 12 Q9Y2L1 1 +Platelet homeostasis 0.1975030947745898 0.0848898469113362 0.9323489636414686 1.0 1.0 12 P30154,Q06124,Q14738 3 +Leishmania infection 0.2033772276411598 0.0846302560546285 0.9325553444969632 1.0 1.0 43 Q00653,P62993,O00401,P35579,Q04206,Q9UQB8,P19174,P60953,Q16539,Q14185,P08238,P17612,P28482,Q9NZQ3,Q7L576 15 +Signal regulatory protein family interactions 0.3534208995796356 0.0836793253588823 0.9333113954561952 1.0 1.0 3 Q06124 1 +Signaling by notch1 0.1912083089447933 0.0834015995670805 0.933532216674288 1.0 1.0 10 Q04727,P49407 2 +M phase 0.2582896581693213 0.0800359449612126 0.9362086677126352 1.0 1.0 199 P68371,P62191,P63151,P43686,P60900,P53350,Q7Z460,Q9HBM1,P25789,Q15008,P42695,O95067,Q9BT25,Q9BUF5,P25786,Q6P1K2,P25787,P50748,P20618,O00487,Q14008,Q99996,O60566,O14818,O14980,O43242,P28066,Q14997,O43684,P55036,P49720,Q96CW5,P61289,P67870,P28070,P49721,Q99661,Q2NKX8,Q01105,P19784,Q9H900,Q92973,Q9P258,Q7Z4H7,Q8IXJ6,P04350,Q9BSJ2,Q9UJX4,Q14203,P07437,Q9NTJ3,O43237,P28482,Q9UIS9,Q7Z5K2,Q6IBW4,Q9HC35,P43034,O75935,Q99986,P30154,P07900,O95347,Q14738,P14635,Q15021,Q15003,Q13885,Q16763,Q14204,P28074,Q15691,P62195,O43264,Q9BPX3,Q13200 76 +Vesicle mediated transport 0.2097053373101217 0.0793733183208324 0.9367356905645708 1.0 1.0 247 P53992,Q7Z392,P61020,Q96KP1,P50395,Q9BUF5,P20645,P47755,O60333,Q9Y6B6,Q99627,Q99661,O15084,P31751,P24386,O95487,P24390,P53618,Q5VZE5,P48444,P50570,P43034,Q8TAG9,Q8TD16,Q9UJY4,Q14204,Q14C86,Q15042,Q9UID3,Q9H0B6,Q9BXS5,Q9UBF2,Q96Q89,P22681,O00743,O15020,O00401,P61923,Q5H9R7,Q86X10,Q96JB2,O43237,Q92734,O75935,O00203,Q13885,Q8TC07,P52732,P47756,Q8N6T3,Q9NVZ3,Q8WTV0,P27348,P63104,O15027,P33176,P49407,P35579,Q14203,Q92538,Q9NZ32,Q92905,P07900,Q9Y5X3,O75351,O43264,O60664,Q01968,P54920,P68371,P62993,P31946,P53621,Q8NC96,Q9Y6G9,O60343,Q15436,Q9Y3P9,Q14789,Q96D71,O00443,P04350,P61201,Q7L5N1,Q9NVG8,Q14746,Q9H9H4,Q00610,O95239,P35606,O94979,Q14677 92 +Cytokine signaling in immune system 0.2505612476233455 0.0787288804059866 0.9372482735286364 1.0 1.0 185 P62191,P62993,O00629,O00170,Q15369,P43686,P61221,P60900,P25789,Q93034,Q9Y3Z3,Q16539,P41240,Q15008,Q14258,P25786,Q6L8Q7,P78417,P20618,P25787,O00487,O15111,P22681,Q00653,P63104,O14818,O15344,O43242,P28066,Q14997,P61081,Q13126,P55036,O43318,P61289,P19174,Q00169,P09429,P51452,O43432,P19474,P29372,O75832,P40763,P28070,P49721,Q8IV63,P78344,Q9UII4,Q13555,Q8TBC4,Q99439,O15357,P31751,Q06124,Q04637,P28482,Q14240,P17987,Q9H3K6,P45985,P07900,P30154,P06730,Q9UHD2,Q14738,P46109,P28074,O60573,Q13501,P42574,P49720,P62195,Q13200 74 +Downregulation of smad2 3 smad4 transcriptional activity 0.25786774566054 0.0781964162736267 0.937671812689872 1.0 1.0 5 Q93008,Q9UPN9 2 +Membrane trafficking 0.2186348026906331 0.0778285115969669 0.9379644662565794 1.0 1.0 240 P53992,Q7Z392,P61020,Q96KP1,Q9BUF5,P20645,P47755,O60333,Q9Y6B6,Q99627,Q99661,O15084,P31751,P24386,O95487,P24390,P53618,Q5VZE5,P48444,P50570,P43034,Q8TAG9,Q8TD16,Q9UJY4,Q14204,Q14C86,Q15042,Q9UID3,Q9H0B6,Q9BXS5,Q9UBF2,Q96Q89,P22681,O00743,O15020,O00401,P61923,Q5H9R7,Q86X10,Q96JB2,O43237,Q92734,O75935,O00203,Q13885,Q8TC07,P52732,P47756,Q8N6T3,Q9NVZ3,P27348,P63104,O15027,P33176,P49407,P35579,Q14203,Q92538,Q9NZ32,Q92905,Q9Y5X3,O75351,O43264,O60664,Q01968,P54920,P68371,P62993,P31946,P53621,Q8NC96,Q9Y6G9,O60343,Q15436,Q9Y3P9,Q14789,Q96D71,O00443,P04350,P61201,Q7L5N1,Q9NVG8,Q14746,Q9H9H4,Q00610,O95239,P35606,O94979,Q14677 89 +Met receptor recycling 0.3428744608799992 0.0754439901971592 0.9398614598004672 1.0 1.0 3 P46109 1 +Translation 0.1899786295287887 0.0726877054401626 0.942054632305529 1.0 1.0 218 Q05639,P84098,P62861,P62906,P61254,P61247,P50914,P46778,P54136,P26639,P27635,P62847,P46199,Q7Z7F7,P13639,Q14240,P18621,P26640,Q9Y285,P49770,P46776,Q9P2J5,Q14232,O76094,P29692,P32969,P62701,P62495,P08708,P47897,P42766,P41252,P39019,Q96E11,Q96I59,Q13144,Q9Y262,P05387,P60059,P62899,P15880,P05198,P39023,P62266,P46783,P62841,Q15056,P62854,P07814,P62269,P61513,P54577,P47914,Q04637,Q9NR50,P06730,O75821,P26641,P62750,P60866,P62917,Q15181,Q14152,P62081,Q9UHB9,O60841,O15371,Q9NSD9,P83731,O43776,P55010,P49591,Q8TAE8,P62753,Q9H2U2,Q9HD33,P49589,P23381 78 +Rho gtpases activate pkns 0.2014961914844483 0.0715158811238803 0.9429871856113072 1.0 1.0 24 P35579,P31946,P27348,P63104,P30307,Q16512,Q16513 7 +P75ntr negatively regulates cell cycle via sc1 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 1.0 2 Q13547 1 +Asparagine n linked glycosylation 0.2066529945619742 0.0710961767597053 0.9433212109764976 1.0 1.0 123 P47756,P62191,P34949,P68371,P53621,Q8N6T3,Q9BUF5,Q9UBF2,Q96IJ6,Q16222,O95394,P47755,Q9Y6G9,O00743,O15020,Q9NR45,Q9Y6B6,O15027,P61923,Q04323,Q06210,Q15436,O15084,Q5H9R7,Q96JB2,P04350,Q14203,O43237,O95487,P24390,Q9UJ70,P53618,P26572,P48444,Q9BV10,Q92734,Q9NZ32,O75935,Q92538,Q14746,P53602,Q13885,Q14204,P54920 44 +Mitochondrial trna aminoacylation 0.1912546920851219 0.0700006190584914 0.9441931669104208 1.0 1.0 18 P47897,P26640,Q9H2U2 3 +Metabolism of amino acids and derivatives 0.2298940820219249 0.0695950540703218 0.944515973677224 1.0 1.0 192 P84098,P62861,P62906,P62333,P61254,P61247,P50914,P46778,P36578,P54136,P25787,O00487,P27635,P28066,P62847,Q13126,P62241,P28070,P23526,Q99707,O00231,P32929,O00330,P18621,P49419,P46776,Q9P2J5,O43252,P00390,Q02543,P25786,P62829,Q13155,P20618,P25325,P61457,P32969,P62701,Q14997,P08708,P55036,P47897,P42766,P41252,P39019,Q9UNM6,P48556,P28072,P25788,P14868,P51665,P05387,P62899,P15880,P62851,P62280,P39023,P62266,P46783,P62841,P62195,P62191,Q14353,Q9Y617,O14818,O43242,P62854,P07814,P61289,P08243,P62269,P61513,P49721,P47914,P28074,P62750,P60866,P62917,P43686,P60900,P25789,Q15008,P62081,P49720,O75832,P19623,P16930,P83731,P49591,P62753,P12277,Q13200 92 +Cargo recognition for clathrin mediated endocytosis 0.2013534287487995 0.0684707839838709 0.9454108764825806 1.0 1.0 32 Q92905,Q96D71,P20645,P61201,Q7L5N1,P22681 6 +Formyl peptide receptors bind formyl peptides and many other ligands 0.5137313432835906 0.0677004958827723 0.9460240545615056 1.0 1.0 2 Q9NRV9 1 +Rho gtpases activate paks 0.173821948215 0.0661263279783857 0.947277250025078 1.0 1.0 13 P35579,P60953,Q13153,Q16512 4 +Rna polymerase ii transcribes snrna genes 0.197946833923105 0.0656658568156511 0.9476438560328768 1.0 1.0 32 P29083,Q9H814,Q6P9B9,P35269,O75909,Q96P16,Q96HW7,Q9NV88 8 +Intra golgi traffic 0.1713086674056755 0.0649215921378447 0.9482364288185332 1.0 1.0 13 Q96JB2 1 +Selective autophagy 0.1931765012310614 0.0637159193415003 0.9491964287021172 1.0 1.0 38 P68371,P07900,P04350,Q9BUF5,Q13501,P67870,Q13885,Q14204,O43237,O60664,P19784 11 +O linked glycosylation 0.2526881720430037 0.0611429105801755 0.951245395356539 1.0 1.0 4 O43505,Q10472,Q86SF2 3 +O linked glycosylation of mucins 0.2526881720430035 0.0611429105801755 0.951245395356539 1.0 1.0 4 O43505,Q10472,Q86SF2 3 +Disorders of transmembrane transporters 0.160657825849858 0.059799278396198 0.9523155003065468 1.0 1.0 73 P62191,P60900,O14818,Q13200,Q15008,P28066,Q14997,P55036,P49720,P20618,P61289,P28070,P28074,P25786,P25787,P62195,O00487,P49721 18 +Hats acetylate histones 0.184530787545763 0.0589501599122849 0.9529918056546124 1.0 1.0 27 O14929,Q6IA86,Q9UPT9 3 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.2458183990441965 0.0569353294569884 0.9545967111099436 1.0 1.0 4 P54619,Q9Y478,Q16539 3 +Organelle biogenesis and maintenance 0.1721046289492556 0.0560835231922924 0.955275269865452 1.0 1.0 95 P68371,Q7Z460,Q16539,Q96KP1,Q9BT25,Q9BUF5,Q3SYG4,Q14008,Q99996,P48735,Q15648,Q9BW83,P49368,Q92973,Q7Z4H7,P04350,Q14203,P07437,P17987,Q9UIS9,Q92538,P43034,O75935,P07900,Q8TAG9,Q13885,Q14204,Q15691,P48643 29 +Trans golgi network vesicle budding 0.1829329749054123 0.0559609456122533 0.9553729192678364 1.0 1.0 36 Q92538,P50570,P54920,Q14677,O00203,Q14789,Q9BXS5,Q9Y5X3,P20645,Q8NC96,Q01968,O00443,P49407 13 +Hiv infection 0.1806573494561362 0.0558678758334045 0.9554470622157476 1.0 1.0 138 P62191,P29083,P43686,Q15369,P60900,P25789,Q8IXH7,Q93034,Q15008,Q9BXS5,P18074,P25786,P20618,P25787,O00487,O14818,O14980,O43242,P28066,Q14997,P55036,P49720,P13984,P61289,O60942,P39748,P28070,P18858,P49721,Q92759,Q9Y5B9,P43487,P18615,P35269,O75909,O75351,P28074,P62195,Q13200 39 +Rab gefs exchange gtp for gdp on rabs 0.1745113545214905 0.0549170665974994 0.9562045352179817 1.0 1.0 27 P31751 1 +Copii mediated vesicle transport 0.1789069703869384 0.0543004080154059 0.9566958244853988 1.0 1.0 33 Q9Y6B6,O15084 2 +Influenza infection 0.1753699591166974 0.0538522342154305 0.9570528929776112 1.0 1.0 127 O00410,P84098,P46776,P62861,O00629,P62750,P62906,P60866,P61254,P61247,P62917,P50914,P46778,P62081,P32969,O14980,P62701,P27635,P62847,P08708,P62854,P13984,P42766,P39019,P62269,P61513,P47914,P83731,P05387,P62753,P18621,P62899,P15880,P07900,P35269,P39023,P62266,P46783,Q00610,P62841 40 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.3018811585547855 0.0532822805296394 0.957506998233737 1.0 1.0 3 P62993,O43865 2 +Formation of fibrin clot clotting cascade 0.2818751866228622 0.0470332475816943 0.9624867291024524 1.0 1.0 3 Q9UNN8,P42785 2 +Host interactions of hiv factors 0.1471287617619493 0.0462079106662685 0.9631445374114294 1.0 1.0 95 P62191,P60900,Q15369,Q93034,Q15008,Q9BXS5,P25786,P20618,P25787,O00487,O14818,O14980,P28066,Q14997,P55036,P49720,P61289,P28070,P49721,P43487,P28074,P62195,Q13200 23 +Activated notch1 transmits signal to the nucleus 0.2591818453269552 0.0425130623715349 0.9660896988984864 1.0 1.0 3 Q96J02,P49407 2 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..331f7de5b086fac80f269d2c30cb728f8dc5fad9 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the phototransduction cascade", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Olfactory signaling pathway", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pou5f1 oct4 sox2 nanog repress genes related to differentiation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory perception of taste", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 dependent activation of irf3 irf7", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trail signaling", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns"], "available_proteins": ["AAAS", "AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD28", "ANLN", "ANO10", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATR", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCL10", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRK1", "BSG", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CENPF", "CENPI", "CENPK", "CERS1", "CERS2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG7", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1A", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EGLN1", "EHD1", "EHHADH", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FIP1L1", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FOXK1", "FOXK2", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS1", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKG", "ILF2", "ILK", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMD1", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LRRC8A", "LRRC8C", "LRRFIP1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MALT1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "MFN1", "MFN2", "MGA", "MGAT1", "MGAT5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLXNA1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RELA", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RNASET2", "RNF2", "RNF20", "RNF31", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SBF1", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC3A2", "SLC5A6", "SLC7A11", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOD2", "SORD", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD7", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX4", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCP1", "TDP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126B", "TMF1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASL", "WBP11", "WDCP", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZFYVE16", "ZNF512B", "ZNF638", "ZNF703", "ZW10", "ZWILCH", "ZZZ3"], "leading_proteins": ["ABCE1", "ABCF1", "ABHD10", "ABHD14B", "ABHD5", "ACADM", "ACAT2", "ACLY", "ACO1", "ACTN1", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADD1", "ADH5", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AHCY", "AHCYL1", "AIMP2", "AIP", "AK1", "AK6", "AKAP9", "AKR1A1", "AKR7A2", "AKT1S1", "AKT2", "ALDH1B1", "ALDH7A1", "ALDOA", "ALDOC", "ALG12", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANKRD28", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP3B1", "AP3M1", "APEX1", "APRT", 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sha256:df83e8b2a8969b3c33cba2709550c25efe7c158a90abfc507ce9ed6b68a9f3aa +size 135946 diff --git a/msigdb_wp/consensus.joblib b/msigdb_wp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..da87f6de38619ccfaced24e294dacdc1045af0f6 --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47b0b059dad834586f1d464e9630a518f0aa70df9ffdc18f6d0c7f1a0d69deff +size 100835 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5b42369284975e62449238ff0c2105decfdb7408 --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,24 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Alzheimers disease 45 87 2.980269917318764 0.0028799449568843 18.929611650485437 83.0752427184466 0.8523996335219438 0.5089902911900335 9.09856474570077 6.061710858604258 1.0800674607776464 0.3865214102951685 0.2283386821273668 0.1133319528150491 0.1927950950158071 0.0002068948255772 +Alzheimers disease and mirna effects 45 89 2.715617952125077 0.006615220718027 19.78640776699029 84.62864077669903 0.8675405351918691 0.5019659822826982 9.06411947478317 6.212690980603589 1.0744065053186531 0.3869842050583563 0.2334599292764838 0.1180365514600679 0.2028496001602897 0.0002572365336763 +Purine metabolism 8 9 2.7146732832924445 0.0066341183277809 4.432038834951456 8.735436893203884 -0.3531083171062636 0.4233052265770069 2.812548634910082 0.9005966487209661 1.1133405174625914 0.3037514098605525 1.0 1.0 0.0274146616230463 4.765057901286244e-06 +Cytoplasmic ribosomal proteins 42 76 2.610645759547043 0.009037145083766 37.88106796116505 74.60194174757281 -1.2114565348655126 0.3153680511516359 14.36226619031951 1.4436994404226102 2.072543722473557 0.3695037094755983 0.3290199976520948 0.5582415000972281 0.0558070993489551 0.0085630435153123 +Dna repair pathways full network 14 51 2.533730477017189 0.0112855497383392 15.157766990291265 49.9126213592233 -0.2457629041265227 0.5422102030419872 7.640710005136936 6.372508911528093 1.0468694202718751 0.3333671650198847 0.1129468594319543 0.0301511358162131 0.0104547730564951 0.0003468229461498 +Nanomaterial induced apoptosis 4 6 2.4269268403366286 0.0152273261603355 1.6553398058252426 5.492718446601942 0.7605691105753482 0.3887043989843749 1.0850464761501173 1.4639504303340525 0.9136336734985344 0.2854277659967253 1.0 0.1566927560007753 0.0683566835720805 0.0013369974246366 +Histone modifications 2 10 2.4051629797510854 0.0161652546508361 2.5679611650485437 8.504854368932039 0.1019905289393476 0.4523705757494653 1.8947404767460905 2.6608407548143336 1.0558854434740854 0.2799140259454132 0.1690349275366953 0.0062109963730023 0.0706809399762649 0.307100773996071 +Cell cycle 26 56 2.4039713246690995 0.016218045389992 13.604368932038836 49.62135922330097 0.0249984674289128 0.7560897539313539 7.374930003933479 5.628665372951865 0.6307917639367615 0.2837424250752632 0.405668833118961 0.0887078471009341 0.1323237158537072 0.0199037385320059 +Base excision repair 6 15 2.402328099389879 0.0162910893271215 6.152912621359223 16.800970873786408 -0.2879657493108331 0.5108252748349887 3.4030848743849873 2.456257914165212 1.0291967772689437 0.3266538784465854 1.0 0.2685126379615966 0.0076999170588955 0.0008647189955035 +Retinoblastoma gene in cancer 15 47 2.310714194714772 0.0208486466678141 13.902912621359222 46.932038834951456 0.0759370557009261 0.6359290150115153 7.276127428212639 3.8231846023107767 0.92369516627564 0.3276008399122643 0.060760732620555 0.1974939061074201 0.001128404999575 3.620947940253145e-06 +Dna mismatch repair 6 19 2.3023017818229383 0.0213181594178424 5.160194174757281 19.174757281553397 0.1547408857460915 0.5270932325531026 3.4632001533411247 1.960419929584235 1.0139907215610702 0.3153217325311915 0.0062995286042916 0.0017973803829616 2.7837297234029546e-05 2.0974178082134003e-05 +Translation factors 22 38 2.2982900564711524 0.0215452860146667 11.012135922330096 36.407766990291265 0.237804702796095 0.5855996076835563 7.095899834901985 1.2400038615965827 1.0529950625688889 0.3465203977253575 0.1993158438352355 0.0748672511655927 0.0056731852980481 1.39107317681815e-05 +Nucleotide excision repair 7 23 2.268753144024993 0.0232833418238027 6.689320388349515 23.68446601941747 -0.003061475141879 0.6436791017602043 3.947542251754899 3.1209364191441753 0.7632489424193469 0.2952462494710732 0.1993158438352355 0.0748672511655927 0.0009539854611851 0.0019780921583714 +Apoptosis modulation by hsp70 4 7 2.258455518647883 0.023917274769815 1.116504854368932 4.37378640776699 0.6980556798635181 0.4553264587927301 1.2564472247640217 1.5830081456928182 0.8995929017617261 0.3096983934223993 1.0 0.1405588989726414 0.0553069748090555 0.0007388687073799 +Purine metabolism and related disorders 10 15 2.24560311282349 0.0247294409281584 7.478155339805825 14.194174757281552 -0.5309087240877612 0.4196717330684614 3.9075491406441913 1.2409536923460405 1.1518146106570497 0.3150369868198264 1.0 1.0 0.0085625102176751 1.2147954097366526e-05 +Mitochondrial long chain fatty acid betaoxidation 1 15 2.1492862632456085 0.0316117147535028 3.349514563106796 13.533980582524272 0.7147062657958151 0.3986109248220331 2.228276960109081 1.0526483843060723 1.0135677936233438 0.2846338064127241 0.0023951619417497 0.0096613748096581 0.0553069748090555 0.1807018090276839 +Il2 signaling pathway 7 11 2.139380605798087 0.0324048563399927 4.536407766990291 9.99514563106796 -0.501234902975295 0.4565412770700209 2.4228152421932116 1.42105380293303 0.9672253821561057 0.3133825089212226 1.0 1.0 0.5413730864422689 0.003914644875648 +Synaptic signaling pathways associated with autism spectrum disorder 4 13 2.0946762913040877 0.0361997781953777 3.388349514563106 10.114077669902912 0.1616055074841362 0.6004388607287494 2.4681780934812103 2.5550437219648225 0.8391828914689811 0.3118788745810285 1.0 0.0049847932658442 0.0115347255989753 0.0319540971359957 +Il3 signaling pathway 9 11 2.07004455128601 0.0384481726301721 4.701456310679611 11.45631067961165 -0.4735778228144983 0.5108456025931012 2.5827466781376467 1.8838954634136185 0.8704377648412869 0.3076953446515831 1.0 1.0 0.5840260458969068 0.0287420990175065 +Cell migration and invasion through p75ntr 4 8 2.057244005260108 0.0396627605628077 1.7912621359223302 5.570388349514563 -0.1762673023897004 0.5663140425891755 1.3146380354662142 1.5757250895770234 0.9016038013605872 0.3137615221082394 1.0 0.1803331870597798 0.0895680133917324 0.0790607116166092 +Nucleotide metabolism 10 13 2.042505145862124 0.0411014495076718 4.310679611650485 13.150485436893204 0.0594667337711415 0.5350250422777217 3.344403022508345 1.536505541452464 0.9582501107125516 0.3095219584025115 1.0 1.0 0.0683566835720805 0.0001429815632908 +Camkk2 pathway 4 13 2.038160841089294 0.041533850245073 2.6820388349514563 11.24514563106796 0.5445336169793533 0.5237007471512424 1.941715715758088 2.1396852885719895 0.7192156127901149 0.2856325720468268 1.0 0.2256640636042331 0.4818833579994148 0.008785557350241 +Dna replication 7 29 2.0162312267107168 0.0437758025502947 7.546116504854369 28.54854368932039 0.0745418454125344 0.6617634495270769 5.2685464794233425 3.1190104255194484 0.7902534153243674 0.3086898617553519 0.0166556908748058 0.0076022823096988 0.000523798345916 0.0009402069411773 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..825dbff3748b0a4e286f8f5f6a4a426b7d582770 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 595, + "title": "Average number of proteins per term", + "value": 11.961344537815126 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..dbdc8eae4398818c105b023871dfc4c3795fe74c --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0ebf3e506aa6e23fac34697d3e9630695b106343 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,320 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Alzheimers disease 0.4799266092820389 2.980269917318764 0.0028799449568843 0.8202232519992119 0.477882712595092 87 P68371,P62191,P55210,Q00535,P43686,P60900,P17655,Q15008,Q9H0B6,Q99570,Q9BUF5,P25786,P20618,P25787,O00487,O15111,O14818,O43242,P28066,P36507,P55036,P49720,P33176,P67870,Q08209,P28070,P49721,P19784,Q14790,Q9Y4P8,P31751,P04350,P07437,P49327,P14735,Q13564,P28482,Q16186,P05198,P28074,Q13885,O14654,P42574,P62195,Q13200 45 +Alzheimers disease and mirna effects 0.4589597400396472 2.715617952125077 0.006615220718027 0.9807285965759536 0.477882712595092 89 P68371,P62191,P55210,Q00535,P43686,P60900,P17655,Q15008,Q9H0B6,Q99570,Q9BUF5,P25786,P20618,P25787,O00487,O15111,O14818,O43242,P28066,P36507,P55036,P49720,P33176,P67870,Q08209,P28070,P49721,P19784,Q14790,Q9Y4P8,P31751,P04350,P07437,P49327,P14735,Q13564,P28482,Q16186,P05198,P28074,Q13885,O14654,P42574,P62195,Q13200 45 +Purine metabolism 0.7816332635357454 2.7146732832924445 0.0066341183277809 0.9809455009098812 0.477882712595092 9 P00813,P30520,Q9BY32,P00492,P20839,P07741,P30566,P31939 8 +Cytoplasmic ribosomal proteins 0.4320732342146156 2.610645759547043 0.009037145083766 0.9954903941737708 0.477882712595092 76 P46776,P84098,P62750,P60866,P62917,P62861,P62906,P61254,P61247,P62263,P50914,P46778,P36578,Q02543,P26373,P62829,P62081,P32969,P62701,P62847,P27635,P08708,P62854,P42766,P62241,P39019,P62269,P61513,P47914,P83731,P62753,P05387,Q15418,P18621,P62899,P15880,P62851,P62280,P39023,P62266,P46783,P62841 42 +Dna repair pathways full network 0.4684968920754447 2.533730477017189 0.0112855497383392 0.9988327214767692 0.477882712595092 51 P28340,P41440,P35244,Q92759,P49005,Q07864,P18074,P20585,Q9Y620,P09429,P29372,Q9UQ84,P18858,Q13535 14 +Nanomaterial induced apoptosis 0.8186821788741852 2.4269268403366286 0.0152273261603355 0.999891628909064 0.477882712595092 6 P55212,P49327,Q14790,P42574 4 +Histone modifications 0.6861875941754407 2.4051629797510854 0.0161652546508361 0.999938527212604 0.477882712595092 10 Q03164,Q86TU7 2 +Cell cycle 0.3994025989754325 2.4039713246690995 0.016218045389992 0.9999404588811096 0.477882712595092 56 P33992,P31946,P33981,P53350,P25205,O95067,P42771,O96017,Q13309,Q13616,Q9H1A4,P27348,P63104,O43684,P11802,O43683,P33991,Q9UBD5,Q9UJX4,P20248,P30307,Q13535,Q99741,Q9UJX5,Q00534,P14635 26 +Base excision repair 0.6800938749852805 2.402328099389879 0.0162910893271215 0.9999430321034738 0.477882712595092 15 P28340,Q07864,P09429,P29372,P49005,P18858 6 +Retinoblastoma gene in cancer 0.4854500150193676 2.3107141947147714 0.0208486466678141 0.9999964054215718 0.477882712595092 47 P35244,P25205,Q07864,O95067,P00374,P26358,P20248,Q00534,P09429,P16949,P14635,Q14527,P49642,Q13309,P23921 15 +Dna mismatch repair 0.6534801817087005 2.3023017818229383 0.0213181594178424 0.9999972978441636 0.477882712595092 19 P28340,P35244,P49005,Q07864,Q9UQ84,P18858 6 +Translation factors 0.558868679540468 2.2982900564711524 0.0215452860146667 0.9999976463910708 0.477882712595092 38 P49770,Q05639,O75153,Q15056,Q14232,P29692,P41567,Q14152,O60841,P62495,O43432,O15371,Q13144,P63241,Q04637,P13639,Q14240,P05198,Q9NR50,P06730,O75821,P26641 22 +Nucleotide excision repair 0.6354630085830759 2.2687531440249935 0.0232833418238027 0.999999182827198 0.477882712595092 23 P28340,P41440,P35244,Q92759,Q07864,P49005,P18858 7 +Apoptosis modulation by hsp70 0.7504490437176454 2.258455518647883 0.023917274769815 0.9999994446805698 0.477882712595092 7 P55212,P49327,Q14790,P42574 4 +Purine metabolism and related disorders 0.6516589800635055 2.24560311282349 0.0247294409281584 0.9999996615901992 0.477882712595092 15 P00813,P30520,Q9BY32,Q06203,P00492,P20839,P07741,P30566,P31939,O15067 10 +Erk pathway in huntingtons disease 0.8473715651134976 2.1987464874029468 0.0278959534446987 0.9999999511249942 0.477882712595092 4 P42574,P28482,P42858 3 +Insulin signaling in adipocytes diabetic condition 0.8383168271141318 2.160755516284974 0.0307142299503124 0.9999999913135366 0.477882712595092 4 P31751,O60343 2 +Insulin signaling in adipocytes normal condition 0.8383168271141318 2.160755516284974 0.0307142299503124 0.9999999913135366 0.477882712595092 4 P31751,O60343 2 +Mitochondrial long chain fatty acid betaoxidation 0.6344064824533845 2.1492862632456085 0.0316117147535028 0.9999999949942564 0.477882712595092 15 P11310 1 +Il2 signaling pathway 0.6359593333828619 2.139380605798087 0.0324048563399927 0.9999999969257471 0.477882712595092 11 P36507,P46109,Q06124,P62753,P28482,P40763,P22681 7 +Synaptic signaling pathways associated with autism spectrum disorder 0.6267180479304916 2.0946762913040873 0.0361997781953777 0.999999999703327 0.477882712595092 13 P21359,Q05086,Q15382,P31751 4 +Hostpathogen interaction of human coronaviruses autophagy 0.8215936988175734 2.0902085322265136 0.0365990714299888 0.9999999997681532 0.477882712595092 4 O95352,Q9NT62 2 +Il3 signaling pathway 0.6232321602499785 2.07004455128601 0.0384481726301721 0.9999999999260812 0.477882712595092 11 P62993,P31946,P27348,P46109,Q06124,P17612,P28482,P40763,P22681 9 +Cell migration and invasion through p75ntr 0.6790099949872513 2.057244005260108 0.0396627605628077 0.9999999999651548 0.477882712595092 8 Q16512,P40763,P31751,Q8TEW0 4 +Nucleotide metabolism 0.61732697087397 2.042505145862124 0.0411014495076718 0.9999999999857198 0.477882712595092 13 P28340,P30520,P00492,P00374,P20839,P11908,P30566,P22392,P31350,P23921 10 +Camkk2 pathway 0.6165470348086535 2.038160841089294 0.041533850245073 0.999999999989081 0.477882712595092 13 Q96EB6,Q13501,Q14155,O00429 4 +Dna replication 0.5713385332604647 2.0162312267107168 0.0437758025502947 0.9999999999972896 0.477882712595092 29 P28340,P41440,Q9UBD5,P35244,P25205,Q07864,P49005 7 +Atr signaling 0.7914569216142611 1.9618584223447544 0.0497789696329729 0.999999999999936 0.477882712595092 4 O60921,Q13535 2 +Il6 signaling pathway 0.6024220514634003 1.959186333924886 0.0500909689881727 0.9999999999999474 0.477882712595092 13 P36507,O43318,Q06124,P28482,P40763 5 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.593397716577225 1.93106072036409 0.0534755438196163 0.9999999999999936 0.477882712595092 17 Q00653,P55210,Q04206,Q14790,P31751,Q16539,O43318,P42574,P28482,O15111 10 +Aryl hydrocarbon receptor pathway wp2586 0.6519138755980776 1.9221670364117165 0.0545847431412052 0.9999999999999968 0.477882712595092 8 P21359,Q04206,O00170,P07900,P48506,P28482,Q16543 7 +Vitamin a and carotenoid metabolism 0.774106610300406 1.8872843159863983 0.0591220948248434 0.9999999999999998 0.477882712595092 4 Q8WTV0 1 +T cell receptor and costimulatory signaling 0.734185986067461 1.878807311515411 0.0602708083503404 1.0 0.477882712595092 5 Q08209 1 +Autophagy 0.5882075949157555 1.877753403579105 0.0604149073544539 1.0 0.477882712595092 10 Q99570,Q96B36,Q9NT62,O95352 4 +Microtubule cytoskeleton regulation 0.5815878422769615 1.8709183805860128 0.0613563949137607 1.0 0.477882712595092 18 Q15691,Q13464,Q13153,Q7Z460,O60610,P16949,P17612,Q16512,P40763,Q99661 10 +Cori cycle 0.5866031496656765 1.8683346733236823 0.0617154365055125 1.0 0.477882712595092 12 P11413,P04075,Q01813,P00558,P18669,P00338,P06744 7 +Glycogen synthesis and degradation 0.5789813142009415 1.8555135594675995 0.0635229247419784 1.0 0.477882712595092 18 Q93100,P63151,Q15257,Q14738,P06737,P13807,P46976 7 +Nonsmall cell lung cancer 0.5801983927568505 1.8539551416732631 0.0637455779610915 1.0 0.477882712595092 17 Q9HC35,Q14790,P19174,P36507,P31751,P42771,Q00534,P42574,P28482,P40763 10 +Il4 signaling pathway 0.5838233436725648 1.852457857200069 0.0639601037813299 1.0 0.477882712595092 11 P22681,P62993,Q16539,Q06124,P28482,P40763,O15111 7 +Hostpathogen interaction of human coronaviruses apoptosis 0.726814670304412 1.845813020904389 0.0649193593145476 1.0 0.477882712595092 5 P42574,P55210,Q14790 3 +Tcell receptor tcr signaling pathway 0.5595904936522892 1.7869349276267332 0.0739480065100779 1.0 0.477882712595092 22 P22681,P62993,Q04206,Q13153,P19174,P36507,Q16539,O43318,P46109,P49327,Q06124,P28482,Q16512,O15111 14 +Melanoma 0.5707429223372066 1.7864142537428565 0.0740322094240786 1.0 0.477882712595092 15 P21359,P36507,P31751,P42771,Q00534,P28482,Q16512 7 +Interleukin11 signaling pathway 0.5702190958724486 1.7833844452904732 0.0745237435252144 1.0 0.477882712595092 15 P62993,O75925,Q04206,Q15257,P36507,Q02750,Q06124,P62753,P28482,Q15418,P40763,O15111 12 +Transsulfuration pathway 0.6198270692611325 1.7600671164979722 0.0783964274621025 1.0 0.477882712595092 8 Q9NZL9,P23526,Q99707,P32929,P26358,P48507 6 +G1 to s cell cycle control 0.5470685624261501 1.759825974292278 0.0784373176265349 1.0 0.477882712595092 25 Q9UBD5,P35244,P25205,Q07864,P42771,Q00534,P49642 7 +Embryonic stem cell pluripotency pathways 0.5656952592167196 1.7513720644783064 0.0798818417245763 1.0 0.477882712595092 13 P62993,P61160,P36507,P52564,P31751,Q06124,P28482,P40763 8 +Bdnftrkb signaling 0.6168082369876927 1.7447058479192383 0.0810360848469249 1.0 0.477882712595092 8 P62993,P19174,Q15334,Q02750,Q15382,P28482 6 +Il5 signaling pathway 0.5628268206342604 1.734282135166279 0.0828680356809321 1.0 0.477882712595092 12 P62753,P36507,P40763,Q06124 4 +Il7 signaling pathway 0.638925353737144 1.726305791990587 0.0842924139136958 1.0 0.477882712595092 7 P36507,P40763 2 +Follicle stimulating hormone fsh signaling pathway 0.6351903001959284 1.7080407981012558 0.0876287725955018 1.0 0.477882712595092 7 P62753,P28482,Q15382,Q16539 4 +Integrinmediated cell adhesion 0.5381308005089961 1.7024360189583974 0.0886736627678956 1.0 0.477882712595092 25 P17655,P41240,P36507,P31751,Q14185,Q14155,O75116,Q16512 8 +Ranklrank signaling pathway 0.5509724164728694 1.69770764421888 0.089562954293904 1.0 0.477882712595092 19 Q00653,P22681,Q04206,P19174,P60953,P31751,Q16539,O43318,Q13501,P28482,O15111 11 +Tnfalpha signaling pathway 0.5235529661357985 1.6959015224445415 0.0899045313060911 1.0 0.477882712595092 29 P62993,P55210,P53350,P52564,Q13546,O15111,Q13616,Q00653,O00221,O43318,Q969G6,Q14790,Q6GQQ9,P28482,Q16543,P45985,P07900,Q9UHD2,P06737,P42574,Q13200 21 +Thymic stromal lymphopoietin tslp signaling pathway 0.553635214887133 1.6841049249977644 0.0921613927340598 1.0 0.477882712595092 14 Q00653,Q04206,P36507,Q9BTU6,Q16539,Q02750,Q06124,P62753,P28482,P40763 10 +Kallmann syndrome 0.6909392979683521 1.6839822837290863 0.0921850926333092 1.0 0.477882712595092 5 P28482,P36507,Q06124 3 +Glutathione metabolism 0.630096036177832 1.6830900335422858 0.0923576635531018 1.0 0.477882712595092 7 P48506,P11413,O75874,P28161 4 +Physicochemical features and toxicityassociated pathways 0.5498375738359753 1.682172425166207 0.0925354095377639 1.0 0.477882712595092 18 P62993,P45985,Q13153,P61160,P19174,Q14012,P35080,O75116,P28482,Q16512,P07737,P22681 12 +Wnt signaling 0.5510543875771537 1.676445233856235 0.0936510150303315 1.0 0.477882712595092 16 O75116,O43318,Q08209,P67870 4 +Translation inhibitors in chronically activated pdgfra cells 0.5432194019630134 1.672229585047667 0.0944790586961441 1.0 0.477882712595092 21 P45985,Q15418,P06730,P36507,P52564,P68400,Q16539,O43432,P31751,Q02750,P17612,Q04637,P62753,P28482,Q14240,Q53EL6 16 +Neural crest cell migration in cancer 0.5492165284268233 1.6606294344735282 0.0967878936158608 1.0 0.477882712595092 10 Q16512,P40763,P31751 3 +Cardiac hypertrophic response 0.546876267886476 1.657437856112702 0.0974309831316384 1.0 0.477882712595092 17 P45985,P36507,P31751,O43318,P28482,Q08209,O15111 7 +Tolllike receptor signaling pathway 0.5449262755133415 1.6527833911036325 0.0983749554898187 1.0 0.477882712595092 18 Q04206,P45985,Q14790,Q9UHD2,P36507,P31751,Q16539,P52564,O43318,P28482,O15111 11 +Nucleotide excision repair in xeroderma pigmentosum 0.5036759064950809 1.643999287394775 0.1001763495729006 1.0 0.4783588939667303 32 P28340,P41440,P35244,Q92759,Q07864,P18074,P49005,P18858 8 +Acute viral myocarditis 0.5425069462329524 1.6382899371582609 0.1013612258377563 1.0 0.4786502331227381 18 Q00653,P78344,P55210,P11940,Q14790,P78310,P09874,P55212,Q13418,Q04637,P42574,P28482,P40763 13 +Homologous recombination 0.5685915179531056 1.62675588523032 0.103788954338448 1.0 0.4862553372549337 9 P28340,P49005 2 +Complement system in neuronal development and plasticity 0.5410644480648572 1.610274184745822 0.1073380123631522 1.0 0.4912778258159659 13 P55210,Q14790,P49327,P42574,Q15398,Q8NI35 6 +15q112 copy number variation syndrome 0.7075089559796484 1.596985960610274 0.1102688367523057 1.0 0.5008393730352816 4 Q06787,Q9BSJ2 2 +Mapk cascade 0.5576108776739703 1.5677354965768906 0.1169428739652613 1.0 0.5261948647738133 9 P62993,P45985,P36507,P52564,Q16539,P28482 6 +Hostpathogen interaction of human coronaviruses mapk signaling 0.5327495356572065 1.5648417119181546 0.1176200285964994 1.0 0.5261948647738133 11 P45985,P06730,P36507,P52564,Q16539,Q02750,P28482 7 +Hijack of ubiquitination by sarscov2 0.6625818237840807 1.5547799623153389 0.1199984829244948 1.0 0.5328290846274213 5 Q13564,Q13617,Q15369 3 +Neural crest cell migration during development 0.5506025906000022 1.529970225338077 0.1260240990862624 1.0 0.5394556759447925 9 Q16512,P40763,P31751 3 +Resistin as a regulator of inflammation 0.5740486214073284 1.5254006406035236 0.1271591990829372 1.0 0.53967634027228 8 P19174,P31751,Q16539,P28482,O15111 5 +Kit receptor signaling pathway 0.524812941532683 1.521711458300915 0.1280813952771979 1.0 0.53967634027228 16 P19174,P36507,Q16539,P46109,Q06124,P62753,P28482,P40763,P22681 9 +Mevalonate pathway 0.6205007446919236 1.5188641026882457 0.1287967064179223 1.0 0.53967634027228 6 Q9BWD1,Q15126 2 +Netrinunc5b signaling pathway 0.522097765492821 1.5011564415082497 0.1333151032237665 1.0 0.5442895439202154 14 Q15257,Q8TCG1,P36507,P30154,Q06124,P42574,P28482 7 +Fatty acid betaoxidation 0.5190146776769706 1.4970884194046858 0.1343702526449997 1.0 0.5442895439202154 18 P11310 1 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.518268754668542 1.492593789702247 0.1355435499649411 1.0 0.5442895439202154 18 P22681,P62993,Q13153,P19174,P36507,P11802,O43318,Q02750,O95433,Q16512,O15111 11 +Hepatocyte growth factor receptor signaling 0.5195324046794644 1.4860748068013832 0.1372593352110507 1.0 0.5443653401917337 13 Q13153,P36507,Q14185,P46109,Q06124,P28482,Q16512,P40763 8 +Aerobic glycolysis 0.5171535573263988 1.4760747917773749 0.1399238152611737 1.0 0.5443653401917337 11 P04075,P08237,P14618,P00558,P00338,P06744 6 +Egfegfr signaling pathway 0.4222982686519715 1.4757043349836338 0.140023281718427 1.0 0.5443653401917337 43 P40818,O15357,Q9P0J0,P19174,P41240,P36507,O14965,P30086,P16949,Q06124,O95630,Q16512,P40763,P22681 14 +Regulatory circuits of the stat3 signaling pathway 0.5395922381968257 1.470510392922479 0.1414235729924979 1.0 0.5443653401917337 9 Q96B36,P40763,P16949 3 +Insulin signaling 0.386717358264722 1.4673184873487386 0.1422894368593423 1.0 0.5443653401917337 48 P41440,Q16539,Q99570,P22681,O60343,Q96PE3,P08237,P36507,P17858,O43318,Q15382,P33176,O15357,P31751,Q06124,P13807,P28482,P46976,Q9H4M9,P45985,P06730,O14654 22 +Brainderived neurotrophic factor bdnf signaling pathway 0.393889989522626 1.4657208260632473 0.1427243581006898 1.0 0.5443653401917337 47 P62993,Q00535,P60953,Q16539,O15111,P19174,P36507,Q96S59,P40763,Q96P70,P13639,P62753,P28482,Q06124,Q14012,P05198,Q04206,P06730,Q13501,P42574,P67809 21 +Egfr tyrosine kinase inhibitor resistance 0.5133062971724823 1.4535733136195628 0.1460646400718177 1.0 0.5474447040568752 16 P21359,P19174,P36507,P06730,P31751,O60573,P62753,P28482,P40763 9 +Regulation of actin cytoskeleton 0.4433480894507012 1.4527544387290532 0.1462919461261229 1.0 0.5474447040568752 39 P15311,Q9UQB8,Q13177,P60953,P41240,Q99570,P46940,O75116,Q16512,P36507,P35241,O00443,Q13464,Q14185,Q14155,Q8TBX8,P28482,Q13153,O60610,P07737,P12814 21 +Intraflagellar transport proteins binding to dynein 0.5105554935304704 1.4424356150527928 0.1491795227026138 1.0 0.5479124444941681 10 Q9BW83,P63172,Q14204,O43237 4 +Alpha 6 beta 4 signaling pathway 0.5566326811219537 1.4353436524443133 0.1511891942859442 1.0 0.5485217719520538 8 P28482,Q16539,Q06124 3 +G13 signaling pathway 0.5080486457107777 1.4224028262151889 0.1549093431569235 1.0 0.5534224917824078 16 O00401,Q13464,O60610,P60953,P46940,O75116,P07737,Q16512 8 +Nad biosynthetic pathways 0.6334030475052288 1.420953265098567 0.1553303464330455 1.0 0.5534224917824078 5 Q96EB6,Q8IXJ6,Q9UGN5,P43490 4 +Ethanol effects on histone modifications 0.5061801357897172 1.4134543313504258 0.1575221802459612 1.0 0.5563492549187926 11 O14929,P41440,Q99707 3 +Biomarkers for pyrimidine metabolism disorders 0.5749654133602267 1.4106918554155607 0.1583354935371219 1.0 0.5563492549187926 7 P11172,P12277,P23921 3 +Methionine metabolism leading to sulfur amino acids and related disorders 0.63071407230357 1.408588335424997 0.1589569299767979 1.0 0.5563492549187926 5 P32929,Q9NZL9,P23526,Q99707 4 +Pyrimidine metabolism 0.4352356297232729 1.3883906677317266 0.1650181165603292 1.0 0.5686561600967623 39 P28340,P11172,Q9BUI4,O14802,Q9BZX2,P15531,P33316,Q07864,P17812,P27708,P04183,P22392,Q9NW08,P49005,P49642,P23921 16 +Network map of sarscov2 signaling pathway 0.4634230162373593 1.3870483467928003 0.1654270209816788 1.0 0.5686561600967623 33 Q00653,Q96B36,Q6PKG0,Q14790,Q9UHD2,O95067,Q15382,P62753,Q9H269,Q14240,P14635 11 +Head and neck squamous cell carcinoma 0.5006594249612243 1.38178851157254 0.1670366475545166 1.0 0.5686561600967623 17 Q00653,Q14790,P31751,P42771,Q00534,Q15382,P62753 7 +Neurodegeneration with brain iron accumulation nbia subtypes pathway 0.5015124071110669 1.3810883024706089 0.1672518117931654 1.0 0.5686561600967623 14 Q96B36,Q9NT62,Q15382,Q13057,O95352 5 +Mthfr deficiency 0.5672560599179626 1.372350782457284 0.1699542638882918 1.0 0.5713151808674217 7 P26358,P35790,P49419 3 +Ebsteinbarr virus lmp1 signaling 0.5405348006923704 1.3518754730054834 0.1764151549609587 1.0 0.5864079173283265 8 Q00653,P07900,O43318,P28482,O15111 5 +Initiation of transcription and translation elongation at the hiv1 ltr 0.4938863205221305 1.3432044167342132 0.1792057919066811 1.0 0.5875536145234915 11 Q08209,P18615 2 +Interferon type i signaling pathways 0.4925444487888022 1.3373902331722651 0.1810952908479874 1.0 0.5875536145234915 18 O75925,P06730,P52564,Q16539,P46109,Q06124,P62753,Q99873,P40763,Q53EL6,P22681 11 +Mapk signaling pathway 0.3868496797033247 1.3363845502065426 0.1814236135226687 1.0 0.5875536145234915 46 P62993,P60953,Q99956,Q16539,Q9UER7,Q16512,O15111,Q00653,P36507,O43318,P16949,P51452,Q08209,P49407,P21359,Q13043,P31751,P49327,P28482,Q04206,Q13153,P45985,P42574,P46109,P17612 25 +Il1 signaling pathway 0.4925096481303508 1.333025204774061 0.182523532591202 1.0 0.5875536145234915 17 Q04206,P45985,P19174,P36507,Q16539,O43318,Q13501,Q06124,P28482,O15111 10 +Il17 signaling pathway 0.5586535638428988 1.3295328896759435 0.1836722223552427 1.0 0.5875536145234915 7 O43318,P40763 2 +Type ii diabetes mellitus 0.7782248990631351 1.3142733598050336 0.1887542289408172 1.0 0.5931505063463478 3 P28482 1 +Epo receptor signaling 0.5552933338797509 1.3128013688851132 0.189249888659289 1.0 0.5931505063463478 7 P62993,P36507,P28482,P40763 4 +Tolllike receptor signaling related to myd88 0.576946615857253 1.3109177417411877 0.1898855561011545 1.0 0.5931505063463478 6 Q00653,P28482,Q9UHD2,O15111 4 +Hedgehog signaling pathway wp4249 0.6084885829979206 1.3062733203500547 0.1914596266246739 1.0 0.5931505063463478 5 Q13618,P49407 2 +Mirnas involvement in the immune response in sepsis 0.5756262048033517 1.3045976892709443 0.1920298755280327 1.0 0.5931505063463478 6 Q00653,O43318,Q16539,O15111 4 +Relationship between inflammation cox2 and egfr 0.7749826354873321 1.301717359370374 0.1930130231044644 1.0 0.5931505063463478 3 P31751 1 +Pdgf pathway 0.4870657469297593 1.3004594215252625 0.1934435553491007 1.0 0.5931505063463478 17 P62993,O00401,P45985,Q13153,P19174,Q06124,P28482,Q16512,P40763,O15111 10 +Nad metabolism 0.6401006613617517 1.2987255848579111 0.19403812053312 1.0 0.5931505063463478 4 Q96EB6,P43490 2 +Praderwilli and angelman syndrome 0.4850571937393312 1.2976900520675978 0.1943938634244333 1.0 0.5931505063463478 10 Q99741,P11802,P42771,Q00534,Q05086,Q9UIS9 6 +Circadian rhythm genes 0.3883298787140639 1.2907997266610265 0.1967731326172159 1.0 0.5973470097308342 45 Q96EB6,Q03164,P00813,Q06210,Q05086,O75116,P43490 7 +Parkinubiquitin proteasomal system pathway 0.4274071940198068 1.2865596940932875 0.1982477999018137 1.0 0.5987687357440568 38 P68371,P62191,P43686,P62333,Q15008,P54652,Q9BUF5,P22314,O00487,Q13616,P68036,O43242,P55036,O75832,Q9UNM6,P48556,Q14790,O00231,P51665,P0DMV9,P07437,P04350,P11142,P35998,Q9BVA1,Q99460,Q13885,Q0VDF9,Q13200,P62195 30 +Cysteine and methionine catabolism 0.5485799701046434 1.2793691758975312 0.2007670830830472 1.0 0.6033152244162279 7 P23526,P48637,Q99707,P48506,P32929,P25325 6 +Angiogenesis 0.7670946551209197 1.2711816891037324 0.2036640192094938 1.0 0.6053765754758914 3 P28482,P19174 2 +Il9 signaling pathway 0.5245343425278625 1.268819736691258 0.2045053641523599 1.0 0.6053765754758914 8 P62993,P36507,P28482,P40763 4 +Nitric oxide metabolism in cystic fibrosis 0.5977084462195134 1.256620955370855 0.2088909229520237 1.0 0.6111705456486817 5 O14744,Q99873,O60678 3 +Apoptosis 0.4780399361109733 1.2546445071184462 0.2096078389415301 1.0 0.6111705456486817 19 P55210,O00221,Q14790,P45985,P42771,P55212,P49327,P42574 8 +Aryl hydrocarbon receptor pathway wp2873 0.6296296296296181 1.2522759158083 0.2104693416531482 1.0 0.6111705456486817 4 P07900,Q16543,O00170 3 +Regucalcin in proximal tubule epithelial kidney cells 0.542524960462648 1.2492170346018563 0.2115857031406727 1.0 0.6111705456486817 7 P42574,Q13283,P28482,Q14790 4 +Nucleotidebinding oligomerization domain nod pathway 0.4765906784212981 1.237326589206719 0.2159658604216801 1.0 0.6177869564947099 13 P55210,Q14790,Q9P0J0,P07900,Q7L5N1,O15111 6 +Thyroid hormones production and peripheral downstream signaling effects 0.4748133578219803 1.2272386794254817 0.2197328955578021 1.0 0.6207400129653704 17 Q96B36,Q7LBC6,O60343,Q15382,P62753 5 +Met in type 1 papillary renal cell carcinoma 0.4696991533997797 1.2251518762550777 0.2205180024676813 1.0 0.6207400129653704 22 P62993,O43815,Q13153,Q13177,P19174,P60953,P36507,P31751,P46109,Q06124,P28482,Q16512,P40763,P22681 14 +Oxidative damage response 0.5373750437712742 1.2235789093010907 0.2211111198261988 1.0 0.6207400129653704 7 P42574,O00221,P45985 3 +Breast cancer pathway 0.4640614808336319 1.2234196600110363 0.2211712315103504 1.0 0.6207400129653704 25 Q00653,P36507,P31751,Q00534,P67870,P28482,Q13535,P19784 8 +Hepatitis b infection 0.4490144448796154 1.2100238352717811 0.2262697469419805 1.0 0.6215492544052313 30 P62993,P31946,Q04206,P27348,P63104,Q14790,P45985,Q9UHD2,P36507,P31751,Q16539,O43318,P49327,P42574,P28482,P40763,O15111 17 +Genes related to primary cilium development based on crispr 0.4717558339138128 1.2093481075076171 0.2265291359407477 1.0 0.6215492544052313 13 Q9BW83,Q7Z392,Q3SYG4 3 +Estrogen receptor pathway 0.7508592270640244 1.20841119954067 0.2268891340258654 1.0 0.6215492544052313 3 P40763 1 +Target of rapamycin tor signaling 0.4703335179684781 1.2042922106408045 0.2284766562824867 1.0 0.6215492544052313 12 Q15382 1 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.7494429991347308 1.2029425840488204 0.2289985398417506 1.0 0.6215492544052313 3 P40763 1 +Il10 antiinflammatory signaling pathway 0.5847800847994064 1.197110844366034 0.2312633536942696 1.0 0.6215492544052313 5 P53004,P40763 2 +Measles virus infection 0.4526439164905199 1.195464054471008 0.2319057722318678 1.0 0.6215492544052313 28 Q00653,P19784,Q14790,Q9UHD2,P11802,O43318,Q00534,P67870,P49327,P42574,P40763,O15111 12 +Methionine de novo and salvage pathway 0.4854987503837598 1.177405856295748 0.2390335535347869 1.0 0.6341987845617011 9 Q13126 1 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.7423121932438481 1.1754291430204484 0.2398230697922398 1.0 0.6341987845617011 3 P19174 1 +Glioblastoma signaling pathways 0.4604224704999509 1.16724267268413 0.2431123824169834 1.0 0.6362703914988261 22 P21359,P19174,P36507,P31751,P11802,P42771,Q00534,P52701,P28482,P22681 10 +Angiotensin ii receptor type 1 pathway 0.6091023767059951 1.1613465763064328 0.2455009854191807 1.0 0.6362703914988261 4 P28482,Q06124 2 +Neovascularisation processes 0.6088509672018755 1.160234705211025 0.2459532605793781 1.0 0.6362703914988261 4 Q00653,P28482 2 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.4571744783882717 1.1395758924970565 0.2544630336337596 1.0 0.6467613159333921 10 P06730,P36507,P52564,Q96KB5,P28482 5 +Pilocytic astrocytoma 0.7327560465810494 1.1386232158514429 0.2548603410407506 1.0 0.6467613159333921 3 P21359,Q06124 2 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.4779307227773178 1.1364923992799425 0.2557505447936299 1.0 0.6467613159333921 9 P49770,Q96B36,O00401,P06730 4 +Ciliopathies 0.4591046522470874 1.1360856500316543 0.2559207201091782 1.0 0.6467613159333921 18 Q9BW83,Q8TD19,P57076,Q15555,Q99570,Q93008,Q13432,Q86Y56,Q01968,Q3SYG4 10 +Hypertrophy model 0.7310389166794218 1.132018759543676 0.2576265476300818 1.0 0.6467839486915558 3 P20248 1 +Serotonin receptor 2 and elksrfgata4 signaling 0.6006076177744548 1.1238120759808017 0.2610927573849024 1.0 0.6473956381245941 4 P36507 1 +Serotonin receptor 467 and nr3c signaling 0.6006076177744548 1.1238120759808017 0.2610927573849024 1.0 0.6473956381245941 4 P36507 1 +Micrornas in cardiomyocyte hypertrophy 0.4492168977846621 1.116266105038488 0.2643082457229688 1.0 0.6512219661811789 24 P45985,P36507,P31751,Q13144,P40763,O75116,P28482,Q08209,O15111 9 +Small cell lung cancer 0.4538529242790152 1.1098481438306016 0.2670644693028441 1.0 0.6512219661811789 12 Q14790,P31751,P11802,Q00534,P42574 5 +Bladder cancer 0.5340694478462293 1.105905564290521 0.2687673961533336 1.0 0.6512219661811789 6 P42771,P28482,P36507 3 +Rac1pak1p38mmp2 pathway 0.4533140451690799 1.101436080518326 0.2707069095235568 1.0 0.6512219661811789 18 P62993,P55210,Q13153,P43246,Q16539,P16949,Q06124,P28482,Q16512,P40763,O15111 11 +Dna damage response 0.4402017538690813 1.0968195470932642 0.2727202835585796 1.0 0.6512219661811789 27 P41440,Q00535,Q14790,P11802,O95067,Q00534,P30307,P49327,P42574,P14635,Q13535 11 +Osteopontin signaling 0.5623876343559494 1.0943139192250797 0.2738173226499492 1.0 0.6512219661811789 5 P28482,Q04206,O15111 3 +Interleukin1 il1 structural pathway 0.4513270245378104 1.0915311383987347 0.2750392380261406 1.0 0.6512219661811789 13 Q04206,P45985,P06730,P36507,P52564,Q16539,O43318,P28482,O15111 9 +Oncostatin m signaling pathway 0.4519876513959197 1.091460398653712 0.2750703481944296 1.0 0.6512219661811789 17 P42574,P36507,P20248,Q06124,P62753,P28482,P40763 7 +Clear cell renal cell carcinoma pathways 0.4019407249213698 1.0899886783708106 0.2757181312898615 1.0 0.6512219661811789 38 P48163,Q9Y617,P04075,P09972,P08237,P14618,P17858,P53396,Q15382,P40763,P00338,P06744,P36871,P49327,Q14012,Q96B36,Q13501,Q01813,P00558 19 +Chromosomal and microsatellite instability in colorectal cancer 0.4501719441883406 1.0807154559280494 0.2798237057307857 1.0 0.6512219661811789 17 Q9UHD2,P31751,P20585,P52701,P42574,P28482 6 +Photodynamic therapyinduced ap1 survival signaling 0.4467889506765041 1.0747047275044863 0.2825069465172256 1.0 0.6540530473842383 11 P45985,P07900,Q16539,P42771,P20248,P49327 6 +Disorders of folate metabolism and transport 0.4848698567766408 1.0635313782737337 0.2875410431648604 1.0 0.663127599546868 8 Q99707,P31939 2 +Gastrin signaling pathway 0.4289844204013509 1.0550601114323177 0.2913978335859479 1.0 0.6646301394596167 29 P62993,Q04206,Q13464,Q13153,P42574,P19174,P28482,Q16539,P42771,P49407,Q06124,P62753,P17612,Q16512,P40763,O15111 16 +Cytosine methylation 0.5535098687217153 1.0537261377455085 0.2920083185878261 1.0 0.6646301394596167 5 P26358,P48735 2 +Proteasome degradation 0.382888161937689 1.0523027585911435 0.2926606664511253 1.0 0.6646301394596167 41 P62191,P60900,P43686,P62333,P25789,Q15008,P25786,P22314,P20618,P25787,O14818,O43242,P28066,P55036,P49720,P61289,O75832,Q9UNM6,P28070,P49721,P48556,P28072,P25788,O00231,P51665,P28074,P62195,Q13200 28 +Onecarbon metabolism 0.4431101739222177 1.039414793769201 0.2986118667084274 1.0 0.6755667706901686 15 P26358,Q99707,P31939,P35754 4 +Pathogenic escherichia coli infection 0.435878348184845 1.0320786520888254 0.3020352735964033 1.0 0.6772862624592818 24 P68371,O00401,P15311,P27348,P63104,Q13464,P60953,P04350,P07437,Q9BUF5,Q13885,O75116,Q92974 13 +Tcell activation sarscov2 0.4418653809396043 1.031703370511173 0.3022110979904915 1.0 0.6772862624592818 17 P62993,P19174,P36507,P42771,Q15382,Q9H1B7,P28482,O15111 8 +Mirna regulation of dna damage response 0.4277613401694798 1.030475601790662 0.3027867996876789 1.0 0.6772862624592818 28 P41440,Q00535,Q14790,P11802,O95067,Q00534,P30307,P49327,P42574,P14635,Q13535 11 +Photodynamic therapyinduced nfkb survival signaling 0.7034935801731809 1.0265696590228126 0.3046231470390135 1.0 0.6788418445251424 3 Q00653,O15111 2 +Disruption of postsynaptic signaling by cnv 0.4758797925848703 1.0173462219126168 0.3089887553703985 1.0 0.6860011546469668 8 P28482,Q06787,Q13555,Q7L576 4 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.5134571894242266 1.0079941603765503 0.3134572656683367 1.0 0.6897289077487602 6 Q07157,P19174,P12814,P28482 4 +Vitamin d in inflammatory diseases 0.4736382156518287 1.0058623992662716 0.3144817658029324 1.0 0.6897289077487602 8 Q04206,Q08209,Q16539,O15111 4 +Hepatitis c and hepatocellular carcinoma 0.4323813544313309 0.9878114347674948 0.3232450063334375 1.0 0.6968506477115773 12 P55210,Q16539,P40763,Q06124,P42574,P31350 6 +Nanoparticlemediated activation of receptor signaling 0.4858553505901335 0.968696968427216 0.3326964055826837 1.0 0.706979861863203 7 P62993,P36507,P28482,Q16539,Q9Y490 5 +Heart development 0.5330203740366204 0.9606215690670148 0.3367424795920386 1.0 0.7114878488321746 5 Q06124 1 +Pyrimidine metabolism and related diseases 0.4839773554229636 0.9595085898422164 0.3373025944409666 1.0 0.7114878488321746 7 P11172,P27708,P23921 3 +Prolactin signaling pathway 0.4238578806471202 0.9569657171029858 0.3385845591701759 1.0 0.7114878488321746 24 P62993,P63104,Q13153,P42574,P36507,Q16539,Q06124,P62753,P28482,Q16512,P40763,P22681 12 +Parkinsons disease pathway 0.444074219379732 0.9549540732600662 0.3396009228039287 1.0 0.7114878488321746 9 P55210,P42574,P68036,Q16539,P55212,P22314 6 +Mbdnf and probdnf regulation of gaba neurotransmission 0.4809220958375683 0.944583722379824 0.3448714404701039 1.0 0.7199947616831993 7 O94973,P19174,P40763,Q13464 4 +1q211 copy number variation syndrome 0.421530027978138 0.9327580259608796 0.3509449175778427 1.0 0.7301126781776798 11 Q9NPH0 1 +Erbb signaling pathway 0.4238439192239913 0.9288986672675028 0.3529416037393376 1.0 0.7317082028742364 19 P62993,Q13153,P45985,P19174,P36507,P31751,P46109,P28482,Q16512,P22681 10 +Signal transduction through il1r 0.4729283289412933 0.9056843953767914 0.3651029242704724 1.0 0.7516824911450902 7 O43318,Q04206,Q16539,O15111 4 +Leptin signaling pathway 0.3963928984159896 0.8914533307675893 0.3726860178866937 1.0 0.7594115775430917 32 P62993,Q04206,O00629,Q13464,P62753,P19174,P36507,P06730,Q16539,Q06124,O75116,P28482,P40763,O15111 14 +Pancreatic adenocarcinoma pathway 0.4115165634293659 0.8808352437724978 0.3784070009618019 1.0 0.7672322188200985 24 P30086,P36507,P31751,P11802,P42771,Q00534,P28482,Q16512,P40763 9 +Bile acids synthesis and enterohepatic circulation 0.6644740324864139 0.8795502891138264 0.3791029787111075 1.0 0.7672322188200985 3 P28482 1 +Caloric restriction and aging 0.5433756607442863 0.8742257719255595 0.3819953136231895 1.0 0.7704651240874499 4 P43490 1 +Nrp1triggered signaling pathways in pancreatic cancer 0.4101816033485643 0.8636863195220981 0.3877602308557337 1.0 0.774406563205789 12 Q00653,P28482,P36507,P31751 4 +Hif1a and pparg regulation of glycolysis 0.540873532352875 0.8635156048692357 0.3878540434207145 1.0 0.774406563205789 4 P00338 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.4621339953473684 0.853552968794207 0.3933527269316528 1.0 0.7819172779150152 7 P07099,Q9BYN0,P48506,P48507 4 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.6570314616151745 0.8519461051897941 0.3942440056714362 1.0 0.7819172779150152 3 P31751 1 +B cell receptor signaling pathway 0.405010883503066 0.8411972146294922 0.4002374606762502 1.0 0.7903725913126856 24 P62993,Q04206,P19174,P60953,P36507,Q16539,O15111,O43318,P46109,Q06124,P28482,P22681 12 +Pentose phosphate metabolism 0.5056477636709492 0.8380751439226264 0.4019885018028857 1.0 0.7903725913126856 5 P11413,O95336 2 +Sulfation biotransformation reaction 0.6530307554493949 0.8371784642936293 0.4024922607861239 1.0 0.7903725913126856 3 P11413,O43252 2 +Interactions between immune cells and micrornas in tumor microenvironment 0.8761194029850748 0.8301137631952354 0.4064744662377517 1.0 0.7955668006955997 2 P40763 1 +Kisspeptinkisspeptin receptor system in the ovary 0.4548833596083711 0.8188337608046131 0.4128812661680898 1.0 0.8028246842157303 7 P36507,P31751 2 +Fluoropyrimidine activity 0.4021595672121794 0.8141063589850632 0.4155840232973324 1.0 0.8035203970972391 13 P11172,Q9BZX2,P00374,P18074,P04183,P31350,P23921 7 +Exrna mechanism of action and biogenesis 0.6462586700216366 0.8123018313229682 0.4166184599956275 1.0 0.8035203970972391 3 Q9HAV4 1 +Nad metabolism sirtuins and aging 0.5282334031781944 0.8097815980582398 0.4180657106960042 1.0 0.8035203970972391 4 P43490 1 +Hostpathogen interaction of human coronaviruses interferon induction 0.416189934377523 0.8087814306928498 0.4186408791599061 1.0 0.8035203970972391 9 O43318,Q9UHD2,Q16539,O15111 4 +Transsulfuration and onecarbon metabolism 0.4015964272689059 0.7995529487974754 0.4239698573947248 1.0 0.8085322600957091 19 Q9Y617,P11586,Q9NZL9,P23526,Q99707,P48506,P00374,P26358,P31153,P32929,P48507 11 +Lncrna in canonical wnt signaling and colorectal cancer 0.3989080121475944 0.78815749088733 0.43060459047911 1.0 0.814441315704257 15 O43318,Q00534,P67870 3 +Inclusion body myositis 0.6393753815491778 0.7871828858483144 0.4311748141963714 1.0 0.814441315704257 3 Q96EB6 1 +Cancer immunotherapy by pd1 blockade 0.6352745634436414 0.7723027413913953 0.4399351421389399 1.0 0.8226149575157108 3 P40763 1 +Nanoparticle triggered regulated necrosis 0.6330247835174713 0.7641674054516951 0.4447674877745695 1.0 0.8269895475808403 3 Q13546,Q14790 2 +Angiopoietinlike protein 8 regulatory pathway 0.367279057526446 0.7557415229977532 0.4498041832975183 1.0 0.8311599039193275 35 P41440,P45985,P06730,P36507,P52564,Q16539,P31751,Q99570,O43318,Q15382,P49327,O14654,P13807,P28482,O00443,P22681 16 +Lipid metabolism pathway 0.387913098299371 0.7366593351154042 0.4613295419908521 1.0 0.8498175773515697 13 P31751,P49327 2 +Agerage pathway 0.3893938652564467 0.7316885903997824 0.4643586619658044 1.0 0.852757419350783 20 Q04206,Q13464,Q14790,O60610,Q16539,P42574,P28482,P15311,P40763,O15111 10 +Wnt signaling pathway 0.3833821113216035 0.712429452440302 0.4761988828175147 1.0 0.866303765393295 13 O43318,Q00534 2 +Supression of hmgb1 mediated inflammation by thbd 0.5046647963324483 0.7115672344087147 0.4767328028026272 1.0 0.866303765393295 4 P09429,O15111 2 +Joubert syndrome 0.3851470892500305 0.7068195782414842 0.479678606241761 1.0 0.866303765393295 19 Q15382,Q3SYG4 2 +Mesodermal commitment pathway 0.3743625082014011 0.6736456181991362 0.5005366434387646 1.0 0.8739676689757677 26 Q9H6R7,P00492,O95071,P42858,Q8N3C0,Q8IWS0,O75717 7 +Canonical nfkb pathway 0.4947420197783496 0.6711503286370865 0.5021247679499359 1.0 0.8739676689757677 4 O00221,O15111 2 +Dual hijack model of vif in hiv infection 0.606748283069566 0.6708002267434171 0.5023478030079203 1.0 0.8739676689757677 3 Q93034,Q15369 2 +Nuclear receptors metapathway 0.2704639282285437 0.6654648379970982 0.5057532261394675 1.0 0.8748184458323839 53 P11310,P21266,O00170,P00390,P48163,Q99615,P23786,Q13616,P11413,Q00653,P11802,P48506,P08238,P52209,P40763,P30043,P11166,Q9HCL2,Q15257,P30041,P49327,Q15185,Q16543,Q9BYN0,P07900,Q13501,P28161,P62195,P48507 29 +Molybdenum cofactor moco biosynthesis 0.6048409827416439 0.6641534859562073 0.5065920803894852 1.0 0.8748184458323839 3 O96007 1 +Dna damage response only atm dependent 0.3766192536467083 0.6599869447517137 0.5092622072920148 1.0 0.8748184458323839 19 Q00653,P31751,P42771,O43318,P09429,P28482 6 +Pi3kakt signaling pathway 0.3316299262756146 0.6583099233768939 0.5103390027702608 1.0 0.8748184458323839 41 P62993,P63151,Q16512,O15111,P36507,P11802,P08238,Q15382,P31751,P13807,P62753,P28482,Q16513,P07900,P30154,P06730,Q14738,Q00534,O60573 19 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.4200748032601268 0.656586287522988 0.5114469683245906 1.0 0.8748184458323839 7 P48506,O15111,P48507 3 +Hippoyap signaling pathway 0.602567930725584 0.656257404056409 0.5116585195792767 1.0 0.8748184458323839 3 P27348,Q13043 2 +Transcriptional activation by nrf2 in response to phytochemicals 0.4616576795526625 0.6483871629123059 0.5167345710348656 1.0 0.8809658159476935 5 P48506,Q13155,P48507 3 +Mirna regulation of p53 pathway in prostate cancer 0.4316608889846796 0.6340678636358764 0.5260365343030735 1.0 0.8917143530208795 6 P42574,Q14790 2 +Integrated cancer pathway 0.3662174594629764 0.6094547654150363 0.542223047015034 1.0 0.90976037952806 16 Q14790,P53350,P11802,P52701,P42574,O96017,Q13535 7 +Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases 0.5882352941176474 0.607137248712217 0.5437598322364485 1.0 0.90976037952806 3 P48506,O75223 2 +Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.4786612344979914 0.6070680100919698 0.543805778873037 1.0 0.90976037952806 4 P28482,O15111 2 +Serotonin and anxiety 0.586387945733857 0.6008945545005295 0.5479102204079445 1.0 0.9131837006799076 3 Q08209 1 +Nanoparticle triggered autophagic cell death 0.4471860887144415 0.5888185788913994 0.5559829813329513 1.0 0.9132772464333588 5 O95352 1 +Phosphoinositides metabolism 0.3712931628413358 0.5856479280641677 0.558112133381151 1.0 0.9132772464333588 9 P19174,Q99570,Q01968,O00443,Q13614 5 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.3588248165305252 0.5798703781687298 0.5620020328463751 1.0 0.9132772464333588 14 P05198,P60228,P55884,Q13347,P55010,O15371,O75821,P41567,Q14152 9 +Focal adhesion 0.3368182018363115 0.5757087867928569 0.5648120351671126 1.0 0.9132772464333588 36 O75116,P17655,P31751 3 +Transcription cofactors ski and skil protein partners 0.4431572163016612 0.5725495144860709 0.5669497511175559 1.0 0.9132772464333588 5 P21359 1 +Ras and bradykinin pathways in covid19 0.4694731624609337 0.5713440580194845 0.5677664419687192 1.0 0.9132772464333588 4 P28482 1 +Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.4007712149964797 0.5708177332011257 0.5681232009718111 1.0 0.9132772464333588 7 P28482,P36507 2 +Sarscov2 innate immunity evasion and cellspecific immune response 0.3543335033512506 0.5629291958966061 0.5734830984996728 1.0 0.9172646333529714 13 Q14258,Q6PKG0,Q14790 3 +Peroxiredoxin 2 induced ovarian failure 0.5730805602273656 0.5565723159259742 0.5778196728798521 1.0 0.921506545624611 3 P42574 1 +Mirna regulation of prostate cancer signaling pathways 0.3482314532231376 0.5545058753855321 0.579232685821184 1.0 0.921506545624611 10 P36507,Q8NCF5 2 +Sterol regulatory elementbinding proteins srebp signaling 0.3367950940845421 0.5421892055352334 0.5876881707241792 1.0 0.9324652308823644 34 Q96EB6,Q8WTV0,Q9NR31,Q9HCL2,P53992,Q9Y6B6,Q15436,P53396,Q13907,O94979,P48449,P49327,P17612,P53602,O95487 15 +Physiological and pathological hypertrophy of the heart 0.3580583012990728 0.524181252015198 0.6001524794116553 1.0 0.9410005924902104 9 P28482,Q08209,P40763 3 +Glycosylation and related congenital defects 0.3571943868560067 0.5202551327059834 0.6028857632155946 1.0 0.9415145121083434 9 P34949 1 +Pdgfrbeta pathway 0.3526025776329214 0.4995771595835463 0.6173728438176813 1.0 0.9591040262963978 9 P19174,P40763,P45985 3 +Spinal cord injury 0.343658790448839 0.4887163127627442 0.6250425531789452 1.0 0.9606167127173372 21 P42574,O75116,P28482,Q08209,P27695 5 +Nodlike receptor nlr signaling pathway 0.4202106910704954 0.482902363094396 0.629165063833987 1.0 0.9606167127173372 5 O43318,O15111 2 +Cellular proteostasis 0.5494925245772782 0.4810974863985728 0.6304472144750402 1.0 0.9606167127173372 3 Q99471 1 +Glucuronidation 0.3917108826859471 0.4688064566834124 0.6392079843815535 1.0 0.9606167127173372 6 O60701,O95394,P36871 3 +Apoptosis modulation and signaling 0.3380737801297721 0.4668685675707739 0.6405939150138429 1.0 0.9606167127173372 17 Q14790,P42771,P55212,Q9UER7,P49327,P42574 6 +Srebf and mir33 in cholesterol and lipid homeostasis 0.3725703054790206 0.4529915245047734 0.6505548445485614 1.0 0.9606167127173372 7 Q96EB6 1 +Fas ligand pathway and stress induction of heat shock proteins 0.3358769051353483 0.4510893502530808 0.6519251529482863 1.0 0.9606167127173372 20 P55210,Q14790,P55212,O43318,Q9UER7,P49327,P42574,Q16512 8 +P38 mapk signaling pathway 0.3293385626664473 0.4510792621914648 0.6519324234320238 1.0 0.9606167127173372 12 P62993,P45985,P60953,P52564,Q16539,O43318,Q9UER7 7 +Vitamin b12 metabolism 0.3254643040709451 0.4486142769558363 0.6537099328928735 1.0 0.9606167127173372 10 Q8WTV0,Q99707 2 +Hypothesized pathways in pathogenesis of cardiovascular disease 0.4328414118438108 0.4367850304052148 0.6622672562910801 1.0 0.9606167127173372 4 P28482 1 +Type 2 papillary renal cell carcinoma 0.3227082377903859 0.4364406044859358 0.662517084194908 1.0 0.9606167127173372 10 Q9GZT9,Q13617,Q15369 3 +Fragile x syndrome 0.2786699485970098 0.4339490714525691 0.6643254243104233 1.0 0.9606167127173372 46 P62993,P42771,Q06787,P19174,P36507,Q15382,P51452,Q08209,P21359,Q15334,Q04637,Q06124,P28482,Q9UPY3,Q14012,Q96B36,P50570,P06730,Q00610,P17612 20 +Sudden infant death syndrome sids susceptibility pathways 0.3237454928331912 0.4254538526650302 0.6705058554452901 1.0 0.9606167127173372 30 Q00653,P11310,P31946,P27348,P04075,P42574,P67809,Q9UIS9 8 +Endometrial cancer 0.3218434298944631 0.4249420676793803 0.6708789069799326 1.0 0.9606167127173372 11 P36507,P31751 2 +Map3k1 role in promoting and blocking gonadal determination 0.4036958207492455 0.4220195937559487 0.6730107158198282 1.0 0.9606167127173372 5 P28482 1 +Interactions between loxl4 and oxidative stress pathway 0.4280181577831428 0.4201514909908778 0.6743747892091285 1.0 0.9606167127173372 4 Q96EB6 1 +Leptininsulin signaling overlap 0.7358208955223922 0.4144954567333563 0.6785112936410149 1.0 0.9606167127173372 2 P40763 1 +Congenital generalized lipodystrophy cgl 0.7325373134328426 0.4061704608792651 0.6846173566604357 1.0 0.9645997619578548 2 P31751 1 +Nocgmppkg mediated neuroprotection 0.3562647272505027 0.3898867577085183 0.6966202863973443 1.0 0.9723955815666524 7 Q13555,Q99996,Q15334,Q04206 4 +Cytosolic dnasensing pathway 0.3206627066782557 0.3882421694860688 0.6978368291243036 1.0 0.9723955815666524 17 Q9BUI4,O14802,Q14790,Q9UHD2,Q14258,Q9NW08,O15111 7 +Nongenomic actions of 125 dihydroxyvitamin d3 0.3253368935051531 0.3841622171803096 0.7008582200256999 1.0 0.9728627612987388 9 Q00653,Q15648,P28482,Q16539 4 +Aflatoxin b1 metabolism 0.7170149253731406 0.3679410394705832 0.712917198392301 1.0 0.9728627612987388 2 P07099 1 +P53 transcriptional gene network 0.3204341867784908 0.3649083188264682 0.7151798443627511 1.0 0.9728627612987388 9 P49327,P13010,P43246 3 +Immune response to tuberculosis 0.4109916367980713 0.3637709501400847 0.7160290570072398 1.0 0.9728627612987388 4 O75925,Q03518,P42224 3 +Endochondral ossification with skeletal dysplasias 0.3625070638502244 0.3603339659493135 0.7185974017607424 1.0 0.9728627612987388 6 P17612,Q9Y376 2 +Endochondral ossification 0.3625070638502244 0.3603339659493135 0.7185974017607424 1.0 0.9728627612987388 6 P17612,Q9Y376 2 +Ncrnas involved in stat3 signaling in hepatocellular carcinoma 0.7032835820895572 0.3357387741112924 0.7370678637739236 1.0 0.9728627612987388 2 P40763 1 +Apoe and mir146 in inflammation and atherosclerosis 0.703283582089556 0.3357387741112904 0.7370678637739252 1.0 0.9728627612987388 2 Q00653 1 +Mapk pathway in congenital thyroid cancer 0.4970750903140322 0.3307445557094207 0.7408374439783365 1.0 0.9728627612987388 3 P36507 1 +Tgfbeta signaling pathway 0.2952118731818962 0.3291172953940407 0.7420670319782028 1.0 0.9728627612987388 35 Q13616,P62993,O75925,Q9Y3F4,Q13464,Q92905,P45985,Q13177,Q7Z3T8,P60953,P36507,P52564,Q16539,O95067,O43318,Q9Y5K5,P28482 17 +Chemokine signaling pathway 0.3046049118858649 0.3281276825250329 0.7428151240537701 1.0 0.9728627612987388 29 P62993,O00401,Q04206,Q13464,Q13153,P41240,P31751,P46109,P49407,O75116,P28482,Q16512,P40763,Q8TEW0,O15111 15 +Rett syndrome causing genes 0.3011158652426459 0.3214434392332894 0.7478743685394393 1.0 0.9728627612987388 14 P49770,P42858 2 +Folate metabolism 0.3046727402067138 0.3194714600988392 0.7493690299331064 1.0 0.9728627612987388 18 Q00653,Q8WTV0,P41440,P23526,Q04206,P11586,Q8NFF5,Q99707,P32929,P00374,Q969G6 11 +Modulators of tcr signaling and t cell activation 0.299639358491709 0.3158305351475132 0.7521311397924173 1.0 0.9728627612987388 14 P62993,P19174,Q93034,O95376,O15111 5 +16p112 distal deletion syndrome 0.3314769078891827 0.3025288892105853 0.7622489141534694 1.0 0.9728627612987388 7 Q8NCF5 1 +Eicosanoid metabolism via lipooxygenases lox 0.3312033262219433 0.3016283648823268 0.7629353824541181 1.0 0.9728627612987388 7 Q8N8N7 1 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.2904958684352936 0.2996332498427665 0.7644569190886095 1.0 0.9728627612987388 11 P67870 1 +Adipogenesis 0.2928177649775926 0.285976697738886 0.7748959690709576 1.0 0.9728627612987388 15 P43490,P40763,P49327 3 +Phosphodiesterases in neuronal function 0.6776119402985117 0.2798693688715413 0.7795777285666916 1.0 0.9728627612987388 2 Q6L8Q7 1 +Ampactivated protein kinase ampk signaling 0.2929611967079984 0.2756885671561563 0.7827872775505678 1.0 0.9728627612987388 18 P31751,P20248,P49327,P13639,P14635 5 +Mecp2 and associated rett syndrome 0.2936788290847045 0.2714106209344461 0.786075234195851 1.0 0.9728627612987388 22 P21359,Q05086,Q14353,P67809 4 +Nrf2are regulation 0.2939863386842835 0.2702188659870694 0.7869918794341426 1.0 0.9728627612987388 9 Q13618,P48506,Q13155,P07947,P48507 5 +Androgen receptor signaling pathway 0.2901542913619672 0.2682180429218491 0.7885314874256388 1.0 0.9728627612987388 29 O75116,Q05086,Q9UER7,P40763 4 +Energy metabolism 0.2886178136832025 0.2671010683517119 0.7893913450417056 1.0 0.9728627612987388 16 Q96EB6,Q16539,Q15648,Q99873,Q08209 5 +Focal adhesion pi3kaktmtorsignaling pathway 0.2620759371463459 0.2575984647381498 0.7967168146960635 1.0 0.9728627612987388 42 P62993,Q96B36,P07900,P30154,P36507,P13807,P31751,P06730,Q14738,Q99570,P08238,O60573,Q15382,O14654,P62753,P28482,Q9Y376 17 +16p112 proximal deletion syndrome 0.2819811604491885 0.2450854760646677 0.8063902484625738 1.0 0.9728627612987388 31 P52564,P30153,P26038,Q8TF05,P04075,P78371,Q9NY27,P49368,Q14790,P50991,Q16204,P40227,P17987,Q99832,Q14738,P15311,P60510,P48643,P78318 19 +Osteoblast differentiation and related diseases 0.270963707015509 0.2404645368516686 0.809970152287451 1.0 0.9728627612987388 10 Q99570,P28482,Q16539 3 +Epithelial to mesenchymal transition in colorectal cancer 0.2843186811027969 0.2395370909039776 0.8106891390406372 1.0 0.9728627612987388 26 P62993,Q13153,Q8TB37,P45985,P36507,P31751,Q16539,P28482,Q16512 9 +Glycolysis in senescence 0.2699219613748663 0.2372377533082169 0.8124723492666 1.0 0.9728627612987388 10 P11413,P09972 2 +Ras signaling 0.276772105886378 0.2354704132215645 0.8138436401385738 1.0 0.9728627612987388 33 P62993,P21359,Q04206,Q13153,Q13043,Q13177,P19174,P60953,P61020,P36507,P31751,Q96KP1,Q02750,Q06124,P17612,P28482,Q16512,O15111 18 +Ethanol metabolism production of ros by cyp2e1 0.6507462686567211 0.2278209116077522 0.819785469033798 1.0 0.9728627612987388 2 P36507 1 +Glucocorticoid receptor pathway 0.3061454429616017 0.2256286688507363 0.8214902412459804 1.0 0.9728627612987388 7 Q13616,P07900,Q15185,Q00653 4 +Amyotrophic lateral sclerosis als 0.2684600827337694 0.2212169700887542 0.824923496349171 1.0 0.9728627612987388 12 Q08209,P36507,Q9UER7 3 +Serine metabolism 0.317167770879423 0.2198769142601005 0.825967016100783 1.0 0.9728627612987388 6 Q9Y617,P00374 2 +Vitamin d receptor pathway 0.2663310745206829 0.2149927350222258 0.8297729827397813 1.0 0.9728627612987388 12 P42771,P49427 2 +Mevalonate arm of cholesterol biosynthesis pathway 0.2632823305660847 0.2116225561964209 0.8324015105639482 1.0 0.9728627612987388 11 Q9BWD1,Q15126 2 +Estrogen signaling pathway 0.3000674587924702 0.2092172626917389 0.8342786369385402 1.0 0.9728627612987388 7 P17612,P28482,Q16539,O15111 4 +Male infertility 0.2744238737057212 0.2064743036142391 0.8364204350293261 1.0 0.9728627612987388 23 Q9Y617,P11586,P41440,P35251,Q15645,Q99707,O75909,P18074,P49327,P13010,P40818 11 +Thermogenesis 0.2710674956164891 0.2034245682948704 0.8388031985250954 1.0 0.9728627612987388 30 O43772,Q15382 2 +Photodynamic therapyinduced hif1 survival signaling 0.2597416262977177 0.2017367505484126 0.8401225304513182 1.0 0.9728627612987388 11 P14618,Q9GZT9,P17858,P00558,P00338 5 +Novel intracellular components of rigilike receptor rlr pathway 0.2553454971803593 0.1691751928897273 0.8656588417334412 1.0 0.9962611428073452 16 Q04206,Q13526,Q14790,Q9UHD2,Q16539,O43318,Q14258,O15111 8 +Unfolded protein response 0.3313988022699032 0.1586469929918236 0.8739470025714544 1.0 0.996513465039792 4 Q14790 1 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.3111354991686118 0.1584033786985167 0.8741389515763218 1.0 0.996513465039792 5 O15111,P61201 2 +Selenium micronutrient network 0.2505233533578739 0.157830674670639 0.8745902267025456 1.0 0.996513465039792 16 Q00653,Q8WTV0,Q04206,Q8NFF5,Q99707,P32929,Q969G6 7 +Malignant pleural mesothelioma 0.1965335251966074 0.141846558271651 0.8872012076667604 1.0 0.996513465039792 76 Q96B36,P31946,P36507,P31751,P42771,Q15382,P67870,P09429,P62753,Q16512,P19784 11 +Nrf2 pathway 0.2496834856196721 0.1407932181665844 0.8880333008165184 1.0 0.996513465039792 25 P30043,P11413,P11166,P21266,Q9BYN0,P07900,P00390,P48163,P48506,P08238,Q13501,P28161,P52209,P48507 14 +Endoderm differentiation 0.2429619674410939 0.1281769369888378 0.8980089511199294 1.0 0.996513465039792 30 P00492,P15531,O95071,Q9BXJ9,Q8N3C0,Q8IWS0,Q86VP6,O14981 8 +Reninangiotensinaldosterone system raas 0.3882427508686704 0.1197337418729892 0.9046940704765888 1.0 0.996513465039792 3 Q13555 1 +Altered glycosylation of muc1 in tumor microenvironment 0.3835064486786905 0.1139800864494972 0.90925357926684 1.0 0.996513465039792 3 O15111 1 +Endoplasmic reticulum stress response in coronavirus infection 0.2653915122534326 0.1098613792303813 0.9125193119947776 1.0 0.996513465039792 6 P05198,P62140,Q96QC0,P62136,P19525 5 +Fibrin complement receptor 3 signaling pathway 0.3012933327909102 0.109463459039866 0.9128349030279556 1.0 0.996513465039792 4 O15111 1 +Dna irdamage and cellular response via atr 0.2256919329576544 0.1092988963523081 0.9129654219355718 1.0 0.996513465039792 38 Q9NUW8,P46063,Q92547,O60921,P30307,O96017,Q9UQ84,Q13535 8 +Gdnfret signaling axis 0.2992831541218528 0.1067373512963404 0.9149973498086116 1.0 0.996513465039792 4 Q9BW83,O94813,P35222 3 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.2302451712235665 0.1042131981429584 0.917000160399942 1.0 0.996513465039792 25 Q15392,Q9BWD1,Q15126,P48449,P49327 5 +Exerciseinduced circadian regulation 0.2177805129413614 0.1015162508953642 0.9191406578515192 1.0 0.996513465039792 15 Q9Y2A7,P78344,P21266,Q16851,Q00577,P25789,Q13907,Q96PU8,P31689 9 +Vitamin dsensitive calcium signaling in depression 0.2464230898214104 0.1006125744645607 0.9198580143831424 1.0 0.996513465039792 7 P11413 1 +Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.2043918112616521 0.0974935517339827 0.9223344548083384 1.0 0.996513465039792 10 Q16512,P27348,Q13153,Q13043 4 +Metapathway biotransformation phase i and ii 0.2238382471967267 0.0974814458787126 0.9223440680932168 1.0 0.996513465039792 22 P07099,Q8NEC7 2 +Ciliary landscape 0.2003683099241883 0.0884476204674403 0.9295209139112052 1.0 0.996513465039792 100 P25205,Q15555,Q96KP1,Q9UL63,Q3SYG4,O60343,O60841,Q96S59,O60942,Q99627,Q9BW83,Q96P70,P61201,Q8IUR7,Q7L5N1,Q92905,P43034,Q8TAG9,Q9Y312,Q14204 20 +Myometrial relaxation and contraction pathways 0.2180921566660387 0.0881042767781416 0.9297937972234224 1.0 0.996513465039792 24 P31946,Q13555,P27348,P63104,Q99439,P19174,P78417,P49407 8 +Dna irdouble strand breaks and cellular response via atm 0.2186943598219798 0.086768127638182 0.9308558225063102 1.0 0.996513465039792 29 P42771,P30307,P42574,Q9UQ84,Q13535 5 +Vegfavegfr2 signaling pathway 0.2564445548888478 0.0840408659355531 0.9330239403589018 1.0 0.996513465039792 184 O00560,P36543,Q15369,P62906,P61254,P17655,P60953,P52564,O75116,O00299,Q14157,Q96SB4,Q01105,Q9BY44,O75569,Q96B36,P45985,Q01844,Q8N3C0,Q9Y613,Q16512,P22681,P04075,P55036,Q08209,Q6Y7W6,P05387,Q9HCE1,P05198,P00491,O60568,P47756,Q16539,Q14694,Q96CT7,Q96KB5,Q9UG63,Q5VU43,Q7Z478,P07814,P09429,P31689,P40763,P52209,P51116,P35579,P20248,P49327,Q06124,Q04637,Q13153,P07900,P06730,Q01968,P07737,P15311,P54920,P62993,P41240,Q9NZB2,P19174,P36507,P48735,Q96PU8,O15371,O15355,Q9NSD9,P78344,Q13464,Q13045,P49591,P62753,P28482,Q15293,Q04206,Q9Y520,Q00610,P24666,P00558 79 +Monoamine transport 0.3523246482166474 0.082768792015327 0.9340353843199568 1.0 0.996513465039792 3 P30307 1 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.1616753890119482 0.041019967351249 0.9672799776136712 1.0 1.0 7 P28482,P61020 2 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..de288aabb3964e365951fc437a3158e5f0cff018 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD5", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSF2", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APMAP", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG7", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AURKA", "B3GALT6", "B3GAT3", "BAG2", "BAG3", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BBS9", "BCAS3", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BLVRB", "BPTF", "BRCA1", "BRD4", "BRIX1", "BRK1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "C1QBP", "C21orf59", "CA8", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBR1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CEP170", "CERS1", "CERS2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLK3", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "CORO1A", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGLN1", "EHD1", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERI1", "ESD", "ESPL1", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GABPA", "GALNT1", "GAMT", "GAPDH", "GART", "GATA6", "GBA", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPRIN1", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H4", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKG", "ILF2", "ILK", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "ITPR2", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "MACF1", "MAD2L1", "MAGED1", "MALT1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MEPCE", "MFN2", "MGA", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MKLN1", "MMAB", "MOCS1", "MOCS2", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPST", "MRE11", "MRPL19", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NARS2", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NONO", "NOP2", "NPC1", "NPC2", "NR2F1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC5", "OSBPL3", "OTUD7B", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PIAS1", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLXNA1", "PMPCA", "PMVK", "PNP", "PNPO", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPM1L", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP4", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SASS6", "SBF1", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SEC13", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SELENOF", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFN", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A25", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC3A2", "SLC5A6", "SLC7A11", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD5", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SPEN", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STX4", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAF6", "TALDO1", "TAP1", "TARBP2", "TARDBP", "TBC1D4", "TBCA", "TBK1", "TBL2", "TCF20", "TCP1", "TDP1", "TDP2", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMEM70", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT2A", "TRRAP", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2J2", "UBE2L3", "UBE2V1", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UPF1", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WASL", "WDCP", "WDHD1", "WDR1", "WDR26", "WDR34", "WDR44", "WDR45", "WDR5", "WDR73", "WDR74", "WFS1", "WIPI2", "WNK1", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["AAR2", "ABCF2", "ACADM", "ACAT2", "ACLY", "ACP1", "ACP6", "ACTN1", "ACTR2", "ADA", "ADRM1", "ADSL", "ADSS", "AHCY", "AHSA1", "AIMP2", "AIP", "AKAP9", "AKT1S1", "AKT2", "ALDH7A1", "ALDOA", "ALDOC", "ANAPC1", "ANAPC4", "ANAPC5", "AP2A2", "APEX1", "APRT", "ARHGEF2", "ARHGEF7", "ARIH2", "ARMC8", "ARRB1", "ASCC3", "ATG3", "ATG7", "ATIC", "ATP6V1E1", "ATR", "AURKA", "BAIAP2", "BBS9", "BLVRA", "BLVRB", "BTAF1", "BUB1", "BUB3", "C21orf59", "CAB39", "CAD", "CAMK1", "CAMK2G", "CAND1", "CAPN2", "CAPZB", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC6", "CDK4", "CDK5", "CDK6", "CDKN2A", "CHEK2", "CHKA", "CHUK", "CIP2A", "CKB", "CLASP1", "CLIC1", "CLTC", "CLUH", "CNN2", "COASY", "COPS2", "COPS5", "COPS6", "COPS8", "CPT2", "CRKL", "CSK", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTH", "CTNNB1", "CTPS1", "CUL1", "CUL2", "CUL3", "CUL5", "CXADR", "CYFIP1", "DAXX", "DHCR24", "DHFR", "DHX29", "DIAPH1", "DICER1", "DLGAP5", "DNAAF5", "DNAJA1", "DNAJC7", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI2", "DYNLT1", "EEF1A2", "EEF1D", "EEF1G", "EEF2", "EGLN1", "EHD1", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3I", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELOC", "EML4", "EPHX1", "EPRS", "ERCC2", "ETF1", "EWSR1", "EXO1", "EXOC2", "EXOC6", "EZR", "FAM120A", "FARSB", "FASN", "FAU", "FHOD1", "FLAD1", "FLII", "FMR1", "FXR2", "G3BP1", "G6PD", "GAMT", "GCLC", "GCLM", "GFPT1", "GGCT", "GIGYF2", "GLRX", "GPAM", "GPI", "GRB2", "GSR", "GSS", "GSTCD", "GSTM2", "GSTM3", "GSTO1", "GTF2H4", "GYG1", "GYS1", "HAT1", "HLTF", "HMGB1", "HPRT1", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA2", "HSPA8", "HTT", "HUS1", "IDE", "IDH1", "IDH2", "IDI1", "IFT27", "IGBP1", "ILK", "IMPDH1", "INPP4A", "INPPL1", "IPO9", "IQGAP1", "IRF2BPL", "IRS4", "ITPA", "KDM3B", "KIF2C", "KIF5B", "KLC2", "KMT2A", "KPNA4", "LARP1", "LDHA", "LIG1", "LLGL1", "LSS", "MAP2K1", "MAP2K2", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MAT2A", "MAT2B", "MBD1", "MCM3", "MCM4", "MCM5", "ME1", "MED1", "MKLN1", "MOCS2", "MOV10", "MPG", "MPI", "MPST", "MSH2", "MSH3", "MSH6", "MSN", "MTAP", "MTHFD1", "MTMR2", "MTR", "MVD", "MYH9", "NAA15", "NAE1", "NAMPT", "NAPA", "NCKAP1", "NDUFA13", "NEK9", "NELFE", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NME1", "NME2", "NUBPL", "OCRL", "ORC3", "OTUD7B", "PABPC1", "PAFAH1B1", "PAK1", "PAK2", "PAPSS1", "PARD3", "PARP1", "PARP2", "PATJ", "PBK", "PDCD4", "PDE12", "PDE4DIP", "PEBP1", "PFAS", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM3", "PHF6", "PHKB", "PI4K2A", "PIAS1", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PKM", "PKN1", "PKN2", "PLCG1", "PLK1", "PLOD3", "PMVK", "PNP", "POLD1", "POLD2", "POLE", "POLR3A", "POLR3B", "POLR3C", "PPAT", "PPM1G", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PRDX6", "PRIM1", "PRKACA", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPS2", "PRRC2C", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMC1", "PSMC2", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME3", "PTGES3", "PTGR2", "PTPA", "PTPN11", "PURA", "PYGL", "QKI", "RAB5B", "RAD54B", "RANBP9", "RCN1", "RDX", "RECQL", "RELA", "RFC1", "RFK", "RHEB", "RIPK1", "RNGTT", "ROCK1", "ROCK2", "RPA3", "RPL10", "RPL10A", "RPL13", "RPL14", "RPL17", "RPL18A", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27A", "RPL29", "RPL3", "RPL31", "RPL35", "RPL37A", "RPL4", "RPL8", "RPL9", "RPLP2", "RPS10", "RPS11", "RPS14", "RPS15", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS3A", "RPS4X", "RPS6", "RPS6KA1", "RPS7", "RPS8", "RRM1", "RRM2", "SAR1A", "SAR1B", "SARS", "SCARB1", "SDCBP", "SEC23A", "SEC24B", "SEC24C", "SEC31A", "SET", "SETD3", "SIRT1", "SIRT2", "SKP2", "SLC19A1", "SLC25A20", "SLC2A1", "SLIT2", "SQSTM1", "SRPK1", "SRXN1", "STAMBP", "STAT1", "STAT3", "STK4", "STMN1", "STRAP", "STRN", "TAP1", "TBC1D4", "TBK1", "TCP1", "TDP1", "TJP1", "TK1", "TLN1", "TOPBP1", "TRAPPC11", "TRIM25", "TRIP13", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "UBA1", "UBAP2L", "UBE2L3", "UBE3A", "UBR5", "UCHL5", "UCK2", "UGDH", "UGP2", "UMPS", "UNC119", "USP10", "USP8", "USP9X", "VPS16", "WASL", "WDCP", "WDHD1", "WIPI2", "XPO5", "XRCC5", "YBX1", "YES1", "YWHAB", "YWHAQ", "YWHAZ", "ZFYVE16"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..205a63c8b0c871e7f64ed8e4f93dd73ca91016ff --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "big_aggregates", "1": "focal_adhesions", "2": "centrosome", "3": "cytoskeleton", "4": "cytoplasmic", "5": "nucleoplasm", "6": 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b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f590a2ce2fbee8f2d06eee778d1601989a4cb13a --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:def52747b072777b494449ba8ddbb57830fe57d414136e6403fbe54d1ea1c1e5 +size 75320 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e6067dab954f7894026f6489cb8b6bda9a65083d --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 97.3529411764706 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..68912b34743f82151147c4a90fe94d92224fe0a5 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b8b2461ca4cb8b10fbfe00d79e0a0a69852a485 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +big_aggregates 0.4847563496923981 1.733012256200996 0.083093490404086 0.7711631545147876 0.2981258433878533 38 Q9BX40,P55210,O00629,P68400,Q9NT62,Q92696,Q99615,Q9Y6D5,O60333,P26196,Q14997,P19784,Q8IV63,P14550,Q92973,P0DMV9,Q9Y5L0,Q8NC56,Q99832,Q9UJX5,P36404,O95239,P53602 23 +focal_adhesions 0.6091668979440557 1.58014452872176 0.1140737717896085 0.8724270762809854 0.3160620682132267 7 Q13153,P41240,Q13418,Q14155,Q16512 5 +centrosome 0.4754415594796206 1.444013809298091 0.1487350909238713 0.9352707714689976 0.3160620682132267 32 P31946,Q14008,P27348,P63104,P33981,P53350,Q7Z460,Q14204,Q9H0B6,Q99661,Q5SW79,P33176,P17612,Q9Y6G9,O43237,Q15691,P00338,O60333 18 +cytoskeleton 0.2830280504031857 0.2828049541812559 0.7773263564162665 0.9999999999918648 1.0 36 P68371,Q9BW19,Q7Z460,P60953,Q9Y6G9,Q14008,Q16181,Q13409,Q9UHD8,Q99661,P35579,Q99439,Q13043,Q8WWK9,P06493,Q15019,O00139,Q9UJX5,P14635,Q5SW79,P12814,P52732 22 +cell_contact 0.2850201691407572 0.2409390439267018 0.8096023606809779 0.999999999999432 1.0 25 Q96N67,Q9UQB8 2 +cytoplasmic 0.411771210794903 0.178782236810832 0.8581086935296174 0.999999999999996 1.0 422 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sha256:bc6658a70989afb9db1869d0a8ad336243e74390790fa90f49ab0e7d5e00f619 +size 132752 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7e2f68ed3c1cfaaa8ed155dcb92ea4071ed17a3b --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3bebc3d2b74a3405810d63bc19d42e1d55f510b3c188922fd2c2e6080a16174f +size 81732 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b62c8405766b71dcd840ea674653a3788d8925c2 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +non-receptor serine/threonine protein kinase 37 65 3.4246494433666888 0.000615593174988 16.135922330097088 52.12621359223301 -0.134221300875087 0.6060262879741318 7.554075018956698 12.250365250469567 0.92962806947858 0.321800658077224 0.6666145180417249 0.1805392177812308 0.4986342897508735 0.4711296330061756 +ubiquitin-protein ligase 34 66 3.1012402994239543 0.0019271183199838 19.58495145631068 59.20631067961165 -0.4503192177737564 0.5340766328058972 8.123146046740304 8.77461359094909 1.127183081820805 0.3533429799231634 1.0 0.1497203102942244 0.4266867661918365 0.0193233655360577 +guanyl-nucleotide exchange factor 6 12 2.819731308984388 0.0048063876333865 2.9490291262135924 8.847087378640778 -0.2661112805277708 0.5117599435401212 2.20762668090836 2.7568830475731176 0.9914761510901344 0.3270659909032961 0.2970322868306702 0.1603727087795495 0.5487644110533858 0.0751078057088052 +translation initiation factor 28 47 2.1820655736508856 0.0291046935306256 12.444174757281552 44.851941747572816 0.1145008827355917 0.6467304989659429 6.887394567659453 2.159854614961781 0.9002593912782545 0.3253626339773532 0.0349867232208153 0.1217041654360116 0.0008211772109777 9.589894388561307e-06 +methyltransferase 3 17 2.122753423545419 0.0337745196795586 3.871359223300971 14.24757281553398 0.1083159719897332 0.5655050447723152 2.576114161276533 2.5612627597162985 0.8801663220809376 0.2923371666369975 0.1651718851687308 0.0519022265935445 0.0665120453316815 0.1190174178925116 +RNA helicase 5 13 1.9876337896602816 0.0468522064416323 6.08252427184466 12.135922330097088 -0.2890679819938573 0.5603983279860386 3.0897552982087326 1.4316026981077965 0.8285436593278585 0.3072596662616214 1.0 0.172526836456327 0.082298412398385 0.00223229240551 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..13747b89affe353e45762431a544fcb6d415304b --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 160, + "title": "Average number of proteins per term", + "value": 14.3 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9e8270494cde7d43298ca126617f7906f186a5bd --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3dcad54e6e4955306d30c9aa0391ddbcc26638fd --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,62 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +non-receptor serine/threonine protein kinase 0.4889445123850926 3.4246494433666888 0.000615593174988 0.0938271766147731 0.098494907998088 65 P49761,Q00535,P33981,P53350,P52564,Q16539,Q96KB5,O75116,Q13546,Q16512,O96017,O15111,O60566,P36507,P11802,O43318,Q96SB4,O43683,P78362,Q8IV63,Q13555,Q13464,Q13043,O14965,P31751,P28482,Q16513,Q14012,Q13535,Q9Y4A5,Q13153,P45985,Q99986,Q9NYV4,Q9UHD2,Q00534,P17612 37 +ubiquitin-protein ligase 0.4610422992731254 3.1012402994239543 0.0019271183199838 0.2655522452456751 0.1206485991018624 66 Q5T4S7,Q92990,Q7Z6Z7,Q93034,Q9NT62,P22314,Q13619,O15344,Q9UBT2,P68036,P61081,Q8IWV7,P19474,Q86VP6,Q13617,Q15386,Q8N806,Q9UII4,Q9ULT8,Q9Y263,Q5TAQ9,Q8TBC4,Q13618,O95071,P61086,Q05086,O95376,Q13564,O95352,Q7Z7E8,O95628,A0AVT1,O94822,Q16763 34 +guanyl-nucleotide exchange factor 0.7644899517790302 2.819731308984388 0.0048063876333865 0.5373923875637129 0.1922555053354635 12 Q92538,Q96N67,Q14185,Q7Z3U7,Q14155,Q9Y6D5 6 +deaminase 0.8905919253203035 2.378043321560615 0.0174047809848927 0.9397518844966208 0.4641274929304728 4 P08397,P00813 2 +translation initiation factor 0.4712321171558126 2.1820655736508856 0.0291046935306256 0.99113692839175 0.4682882729118167 47 P49770,O75153,Q15056,Q14232,Q9ULC4,P41567,O00487,Q14152,Q9Y3F4,O60841,Q9UJA5,P46199,O43432,O15371,P78344,Q9BY44,Q13144,Q9Y262,P41214,P63241,Q04637,Q7L5N1,P05198,Q9NR50,Q92905,P06730,O60573,O75821 28 +methyltransferase 0.6265792489069981 2.122753423545419 0.0337745196795586 0.9959021338181266 0.4682882729118167 17 Q86TU7,Q9BV86,Q86W50 3 +RNA helicase 0.6074985358678886 1.9876337896602816 0.0468522064416323 0.9995369376219222 0.4695580070061171 13 Q7Z478,Q6P158,Q8IX18,O60231,Q9H6S0 5 +kinase activator 0.6626054282740063 1.8415047480706728 0.0655476254314451 0.999980539790364 0.4695580070061171 7 Q93100,P20248,O95067 3 +tubulin 0.6511003442627634 1.785667923297136 0.0741530419824463 0.9999955713369688 0.4695580070061171 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +carbohydrate kinase 0.6970421272781531 1.7116496187355863 0.0869612583866865 0.999999523269529 0.4845356467687549 5 Q01813,P51570,P17858,P08237 4 +translation factor 0.6349775784753428 1.706999819327625 0.0878220859768368 0.999999590052315 0.4845356467687549 7 Q05639,P51114,Q9Y450,P51116,Q06787,Q53EL6 6 +kinase modulator 0.6329786660162131 1.5781155959860549 0.1145390559024956 0.9999999964754342 0.5390073218940974 6 P67870 1 +transporter 0.3225764040096147 1.5425950464669362 0.1229290606695316 0.9999999992316564 0.5535500687307273 61 P41440,O15397,O00629,O43772,Q567V2,O60830,Q9Y5L0,Q00169,Q96P70,Q9HAV4 10 +protease 0.4289641968844344 1.53281968564185 0.1253202888733926 0.999999999503581 0.5535500687307273 43 P62191,P55210,P60900,P43686,Q9NQW7,P25786,P20618,P25787,O14818,O43242,P28066,P55036,P49720,P28070,P49721,Q14790,P55212,P28074,P42574,P50579,P62195,Q13200 22 +cysteine protease 0.4802815599743429 1.4019668341509104 0.1609251508129259 0.9999999999993572 0.6018844976676127 29 Q86UV5,Q9UPT9,O94966,Q96K76,P17655,Q6GQQ9,Q14694,Q93008,P45974,Q96FW1,Q9Y4P1,P51784,Q96RU2,Q01804,P40818 15 +histone modifying enzyme 0.5015221131323623 1.3811449747661533 0.1672343894662571 0.9999999999998078 0.6018844976676127 14 O14929,Q03164 2 +serine protease 0.4967117572408488 1.362544053198859 0.1730262513137541 0.999999999999937 0.6018844976676127 18 P48147,Q16740 2 +cytoskeletal protein 0.5588762701733442 1.2244224959854697 0.2207928872566396 1.0 0.6926835678639673 6 Q9P0V9,Q16181,Q14141,Q9UHD8,Q15019 5 +non-motor microtubule binding protein 0.4636382088152727 1.1791934880263373 0.2383211385341677 1.0 0.6949451402801934 21 Q14008,Q66K74,P13693,Q9UH99,Q7Z460,Q15555,Q9BSJ2,Q96CW5,P78559,Q15691 10 +defense/immunity protein 0.7406177434264264 1.1688970378168309 0.2424451171262078 1.0 0.6949451402801934 3 Q8IWZ3 1 +phosphatase modulator 0.5217622174984146 1.145945218670693 0.2518178195435754 1.0 0.6949451402801934 7 P30154,Q8TF05 2 +RNA methyltransferase 0.4589281637497375 1.135272834909372 0.2562610204783213 1.0 0.6949451402801934 13 Q9BV44,Q7Z2T5,Q08J23,Q7Z4G4 4 +pyrophosphatase 0.7240967452970886 1.1053499403496876 0.2690079860924532 1.0 0.707676101085855 3 Q9UKK9,Q9H2U2 2 +aldolase 0.7228853295600944 1.100701868770551 0.2710264326582912 1.0 0.707676101085855 3 P09972 1 +transcription cofactor 0.443716277684974 1.0520523994115796 0.2927755095022959 1.0 0.7204291155107309 12 O00625,Q7Z4V5 2 +translational protein 0.7080555756428139 1.0439591629461713 0.2965042837718075 1.0 0.7204291155107309 3 O95260 1 +nucleotide kinase 0.4419433927479776 1.0377484380117297 0.2993871876872644 1.0 0.7204291155107309 13 P00491,Q9BZX2,P00568,Q13126,Q14558,P11908,P04183,O60256 8 +decarboxylase 0.5468991977285169 1.0235898797796452 0.3060290272869921 1.0 0.7204291155107309 5 P30046 1 +calmodulin-related 0.43768389921205 1.0232654090014877 0.3061823740920606 1.0 0.7204291155107309 11 Q15293,Q14257 2 +kinase 0.4307688596328958 0.9779656857266286 0.3280912957430084 1.0 0.7399684725582389 21 Q13572,Q15126,P15531,P35790,Q9NVE7,P42356 6 +chaperonin 0.4220345945444988 0.9425331133987722 0.3459197660412174 1.0 0.7399684725582389 10 P49368,Q99832,P50991,P40227,O75347,P17987,P48643 7 +translation release factor 0.6645010187691238 0.8796506782791568 0.3790485759761148 1.0 0.7666726903917915 3 Q96E11 1 +microtubule binding motor protein 0.4075828160916637 0.8394413246373665 0.401221702376795 1.0 0.7828716143937464 21 O75935,O60333,Q9H0B6,Q15058,Q96Q89,Q14204,P52732,Q99661 8 +Rel homology transcription factor 0.6437742609734347 0.8032155933500068 0.4218501341944742 1.0 0.7940708408366575 3 Q00653,Q04206 2 +DNA helicase 0.3951883121831084 0.7882150616876562 0.4305709205426975 1.0 0.8010621777538559 11 Q9H4L7,P18074 2 +DNA metabolism protein 0.3518707889433426 0.7200068748647512 0.47152076269742 1.0 0.8476777756358113 38 P28340,P38935,P54277,P25205,Q07864,Q92547,O60921,P20585,Q15477 9 +GTPase-activating protein 0.3774244867137813 0.6809046159661502 0.4959318471236309 1.0 0.8816566171086772 13 P21359,Q8N6T3,O60343,Q9NVG8,Q9Y3P9,Q8TC07,Q15042 7 +aminoacyl-tRNA synthetase 0.3566178298975835 0.6485536189216907 0.5166269428247297 1.0 0.908355064307217 33 Q9P2J5,Q96I59,P26639,O43776,P26640,P49591,P07814,P41250,P47897,P49589,P41252,P23381,P54136,Q9Y285,Q9NSD9 15 +exodeoxyribonuclease 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.9221789246409268 2 Q9UQ84 1 +mRNA capping factor 0.7886567164179156 0.5587068144366598 0.5763618279005793 1.0 0.9221789246409268 2 O60942 1 +hydrolase 0.3521876347612498 0.5482680434603092 0.58350786666273 1.0 0.9243688976835328 26 Q86WA6,Q9BPU6,Q9HB07,Q9NX46,Q96C86,Q9NQR4,Q9Y3Z3,O60502,P07099 9 +protein-binding activity modulator 0.4127528542593374 0.454997374327886 0.649111127809562 1.0 0.9853515050605604 5 Q9UNN8,O14737 2 +general transcription factor 0.3221819159852946 0.4350086368747313 0.6635561583238598 1.0 0.9853515050605604 32 P53999,P29083,Q15369,Q92759,O95163,P35269 6 +primase 0.7313432835820937 0.4031633864812186 0.6868280325873308 1.0 0.9853515050605604 2 P49642 1 +G-protein modulator 0.3729826658696865 0.3978242896114359 0.6907597113711321 1.0 0.9853515050605604 6 Q9H2M9,P50395,P26374,P24386,P52565 5 +translation elongation factor 0.3115765388893237 0.3683499268539044 0.7126123291823907 1.0 0.9853515050605604 13 Q8NE71,P29692,Q7Z2Z2,P13639,O00178,Q9UG63 6 +microtubule or microtubule-binding cytoskeletal protein 0.3000038201330324 0.3285514281769967 0.7424947662183681 1.0 0.9853515050605604 12 Q08378,Q96EX3,O43264,Q9Y266,P63172,O43237,Q9Y6G9 7 +phosphodiesterase 0.3452511729170223 0.3024667136428258 0.7622963044886402 1.0 0.9853515050605604 6 Q9NZC3,Q9NUW8 2 +metalloprotease 0.2872132257366718 0.2515143763067544 0.8014164486742925 1.0 0.9853515050605604 27 P55786,Q9NY33,O43847,P52888 4 +membrane traffic protein 0.2002138394195608 0.2404401917070743 0.8099890234017046 1.0 0.9853515050605604 61 O00221,P50570,Q92734,Q9H4M9,Q9Y2T2,Q9H6H4,O00429,Q8TAG9,Q13432,Q96D71,P20645,Q9H269 12 +dehydrogenase 0.1997882039273951 0.2060048125595529 0.8367871520561303 1.0 0.9853515050605604 66 P11413,P11310,O60701,Q9P0J0,P53004,P48735,P20839,Q00796,P49419,Q96CU9 10 +nucleotide phosphatase 0.3074909013928988 0.1950366281098703 0.8453642731119995 1.0 0.9853515050605604 6 Q5TFE4 1 +homeodomain transcription factor 0.347968936678603 0.1925517288577702 0.8473100521377186 1.0 0.9853515050605604 4 O94776,P31260,P31277 3 +non-motor actin binding protein 0.2623785711706855 0.1859692624091587 0.8524688658604518 1.0 0.9853515050605604 33 P47756,Q99439,P35611,Q6IBS0,Q9UEY8,P35080,P07737,P47755,P60981,P57737 10 +lyase 0.2206389674005204 0.1108421239881624 0.9117415410283698 1.0 0.9853515050605604 13 Q9UHG3 1 +mutase 0.2484492311910704 0.1035440641446552 0.917531179282183 1.0 0.9853515050605604 7 P18669 1 +apolipoprotein 0.5588059701492611 0.1018874670546138 0.918845998031038 1.0 0.9853515050605604 2 Q9BQE5 1 +scaffold/adaptor protein 0.1917532251700274 0.0921448519946193 0.926582953270652 1.0 0.9853515050605604 88 P31946,Q9UQB8,Q8NHU6,Q92796,Q9NZQ3,P27348,P63104,Q96S59,Q99627,P49407,O15084,Q08AM6,Q92616,Q9UNF1,Q96T76,P43487,Q5VYK3,Q9Y5X3,P46109,Q9UBB6,Q8N3C0,O60664,Q5SW79,Q15398,Q00013 25 +ribosomal protein 0.1141854078668713 0.0494328328166576 0.960574363332582 1.0 0.9853515050605604 117 P46776,P84098,P62750,P60866,P62917,P62906,P61254,P61247,P50914,P46778,P62081,P32969,P62701,P27635,P62847,P08708,P62854,Q7Z7F7,P42766,P39019,P62269,P47914,P83731,P05387,P62753,P18621,P62899,P15880,Q9HD33,P39023,P62266,P46783,P62841 33 +basic leucine zipper transcription factor 0.4292537313432932 0.0380857344850357 0.9696193252904824 1.0 0.9853515050605604 2 Q7L1Q6 1 +damaged DNA-binding protein 0.3943283582089614 0.0338025390346205 0.9730346112473034 1.0 0.9853515050605604 2 P54727 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..788a0960f054e378b54a163c9667acd0b62c3c21 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligand-gated ion channel", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD28", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOL2", "APRT", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGDIA", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD2B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BDH2", "BLM", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX4", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP170", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENOPH1", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAHD1", "FAHD2A", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXC1", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HUS1", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "ISCU", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MBNL1", "MCCC1", "MCCC2", "MCEE", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NENF", "NF1", "NFKB2", "NFKBIE", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPN1", "PACSIN2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM34", "RBM4", "RBM47", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNF31", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A11", "S100A13", "SACM1L", "SAE1", "SAMHD1", "SAP18", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP1", "TDRD7", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM38B", "TMOD3", "TMPO", "TMX2", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAF2", "TRAP1", "TRAPPC4", "TRIM21", "TRIM24", "TRIM26", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBP1", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGCG", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VMP1", "VPS13D", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS53", "VRK1", "VRK3", "WARS", "WASF2", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR4", "WDR74", "WDR82", "WNK1", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YEATS2", "YEATS4", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFR", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF326", "ZNF598", "ZNF644", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["ABCF1", "ABCF2", "ACADM", "ADA", "ADD1", "ADD3", "ADPRHL2", "AK1", "AKT2", "ALDH7A1", "ALDOC", "ANKHD1", "ANKRD28", "AP3M1", "APOL2", "ARFGAP1", "ARFGEF2", "ARHGDIA", "ARHGEF7", "ARIH2", "ARRB1", "ASCC3", "ATE1", "ATG3", "ATG4B", "ATG7", "ATR", "AURKA", "BAIAP2", "BLVRA", "BPHL", "BUB1", "BUB1B", "BZW1", "CAMK1", "CAMK2G", "CAND1", "CAPN2", "CAPZA2", "CAPZB", "CARS", "CASP3", "CASP6", "CASP7", "CASP8", "CCNA2", "CCNB2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CDK12", "CDK4", "CDK5", "CDK6", "CEP170", "CHEK2", "CHKA", "CHM", "CHML", "CHUK", "CKAP5", "CLASP1", "CLK3", "CLPP", "CLUH", "CNN2", "CNOT4", "COPS5", "COPS6", "COPS8", "CORO7", "CRKL", "CSNK2B", "CUL2", "CUL3", "CUL4A", "CUL5", "DCAF8", "DCPS", "DCTN3", "DDT", "DHX16", "DHX29", "DHX40", "DHX57", "DLG3", "DLGAP5", "DNM1L", "DNM2", "DOCK1", "DOCK7", "DPP3", "DPYSL5", "DSTN", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLT1", "EEF1A2", "EEF1D", "EEF2", "EFL1", "EHD1", "EIF1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF3A", "EIF3D", "EIF3G", "EIF3L", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF5B", "ELOC", "ELP1", "EPHX1", "EPRS", "ERCC2", "EXO1", "EXOC6", "FARSA", "FARSB", "FMR1", "FOXRED1", "FXR1", "FXR2", "G6PD", "GALK1", "GARS", "GBF1", "GCN1", "GDE1", "GDI2", "GLMN", "GOLGA3", "GTF2E1", "GTF2F1", "GTF2H4", "GTPBP1", "HAT1", "HBS1L", "HDGFL2", "HECTD1", "HERC5", "HMBS", "HOXA10", "HOXD11", "HUS1", "HUWE1", "IARS", "IDH2", "IGHMBP2", "IMPDH1", "IPO8", "IPO9", "ITPK1", "KIAA0368", "KIF11", "KIF14", "KIF1B", "KIF20B", "KIF2C", "KLC2", "KMT2A", "KPNA4", "LARS", "LTN1", "M6PR", "MAGED2", "MAP1A", "MAP1S", "MAP2K2", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MCM3", "MCTS1", "METAP2", "METTL16", "MGEA5", "MID1", "MMS19", "MON2", "MPP1", "MPV17L2", "MRPL47", "MRPL55", "MRRF", "MSH3", "MTA2", "MTAP", "MTIF2", "MYG1", "NAE1", "NARS", "NARS2", "NCDN", "NCKIPSD", "NDUFA13", "NF1", "NFKB2", "NFKBIE", "NIT2", "NME1", "NPEPPS", "NRDC", "NSUN2", "NT5DC1", "NTMT1", "NUDC", "NUDT5", "OTUB1", "OTUD4", 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0000000000000000000000000000000000000000..7f0cbd23238fa749d97706055eaf751f94082b0a --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c036372a4c94eb7e7f1262638d2440020a33618f59096c633e73e5756688523 +size 134820 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..810e06947d3583bfbbf2ad491248d766943dc235 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f6ca0e4e7271c6059bd31bb5151684873f849f0b3b1c607fe9dacfc9410c9ac +size 216224 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e3b2909d64b4a846ce41bdb56b76a3b8700526d0 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Protein kinase 42 82 2.783745323495453 0.0053735208610738 20.09223300970874 68.12135922330097 -0.1885407530168121 0.6382294404073665 8.905449289760881 14.39153709303092 0.8281308874650661 0.3147542738878373 0.8070839492565165 0.4200540884295293 0.741919771246945 0.7286927740005684 +Microtubule family cytoskeletal protein 25 51 2.4952550016293684 0.0125866640738401 13.95388349514563 44.689320388349515 -0.1362213656804705 0.619784536589291 6.314208777929424 5.456410011879574 0.9169883864186168 0.3228121160578749 0.405668833118961 0.6553977822892062 0.1323237158537072 0.0452876692762686 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cced4d5610b7474567529f1fce74e6e2b9b13cc2 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 2110, + "title": "Average number of proteins per term", + "value": 3.1516587677725116 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9c16eca5e8371d979a923173e10970bc0cfc5e3e --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e7490f353ca0884e20e75296c2b8d49e9286a613 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,92 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein kinase 0.4555185185469302 2.7837453234954532 0.0053735208610738 0.9999884485712048 0.2878833833028998 82 P49761,Q00535,P33981,P53350,P41240,Q8TD19,P52564,Q16539,Q99570,Q96KB5,O75116,Q16512,O96017,Q13546,O15111,O60566,P36507,P11802,O43318,P67870,Q96SB4,P19784,P78362,Q8IV63,O43683,Q13555,Q13464,Q13043,O14965,P31751,P28482,Q16513,Q14012,Q13535,P45985,Q13153,Q99986,Q9NYV4,Q9UHD2,Q9H2G2,Q00534,P17612 42 +Microtubule family cytoskeletal protein 0.4645797249832568 2.4952550016293684 0.0125866640738401 0.9999999999975292 0.2878833833028998 51 P68371,Q15555,Q9BUF5,Q96Q89,P78559,O60333,Q14008,P13693,Q9UH99,Q96CW5,P33176,Q9BTW9,Q99661,Q66K74,P04350,Q9BSJ2,P07437,O43237,Q15058,O75351,O43264,Q13885,P63172,Q15691,P52732 25 +Extracellular matrix glycoprotein 0.7904191004845001 1.9574113533749689 0.0502991247351489 1.0 0.2878833833028998 4 Q9Y2T2,Q32P28 2 +Deaminase 0.7876644900384993 1.9455993152670377 0.0517028893366706 1.0 0.2878833833028998 4 P08397,P00813 2 +Kinase 0.4288861178946278 1.9450344565829405 0.051770831402861 1.0 0.2878833833028998 119 P49761,Q00535,P33981,P53350,P41240,Q8TD19,P52564,Q16539,Q99570,Q96KB5,P22392,O75116,Q16512,O96017,O15111,Q13572,O60566,P08237,P14618,P36507,P11802,P17858,O43318,P11908,P67870,Q96SB4,O00443,P19784,P78362,Q8IV63,O43683,Q13555,Q13464,Q13043,O14965,P31751,Q8TBX8,P04183,P28482,P17612,Q16513,O75569,Q14012,Q13535,Q9UJ70,P51570,P45985,Q9BZX2,Q13153,Q99986,Q9NYV4,P15531,P00568,P35790,Q9UHD2,O00764,Q9H2G2,Q00534,Q9NVE7,P12277,P30085,Q01813,P42356,P00558 64 +CMGC group 0.5822192947033972 1.8971333511124204 0.057810340480116 1.0 0.2959111947049903 20 P78362,P49761,Q00535,P11802,Q00534,P67870,P28482,P19784 8 +AGC group 0.5861541778231574 1.865442511388196 0.0621194032590703 1.0 0.3048208716201875 11 O75116,P31751 2 +Kinase activator 0.6318551931942153 1.8210895383024113 0.0685932472978954 1.0 0.3167724911176192 8 Q93100,P14635,P20248,O95067 4 +RNA helicase 0.5738265436407958 1.7966141779056664 0.072396892017601 1.0 0.3194937691511167 11 Q7Z478,Q8IX18,P42694,Q6P158 4 +Tubulin 0.6511003442627634 1.785667923297136 0.0741530419824463 1.0 0.3212108260725239 7 P68371,P04350,P07437,Q9BUF5,Q13885 5 +Translation initiation factor 0.5546803391029111 1.7565256918874526 0.0789986885037925 1.0 0.3283273762828735 22 P78344,P05198,O75153,Q9UJA5,P06730,Q9Y262,O43432,Q15056,P63241,O60573,O15371,Q04637,Q86TB9,Q14152 14 +Eraser 0.6434821989843551 1.7485557496630808 0.0803678409339623 1.0 0.3295985894880299 7 Q96EB6,Q7LBC6 2 +Other group 0.5582194344524855 1.7138092855493607 0.0865637574975632 1.0 0.3376146549350435 15 O60566,P33981,P53350,Q9UHD2,Q8TD19,O14965,Q99570,Q96KB5,O15111 9 +DNA helicase 0.5532601954313915 1.6799829570436209 0.0929606317298572 1.0 0.3447222020210875 12 P25205 1 +Helicase 0.534444558081419 1.660918282100692 0.0967298599634245 1.0 0.3503283689636357 24 Q7Z478,Q9H4L7,Q6P158,P25205,P42694,Q8IX18,P46063,A3KN83 8 +Methyltransferase 0.5368700071738516 1.5893055338291266 0.1119914300007391 1.0 0.37456827560045 15 Q9UBP6,Q9BV86 2 +Protein arginine methyltransferase 0.6869772998805187 1.5064412166744214 0.1319539466875983 1.0 0.4048392674522267 4 O14744,Q99873,O60678 3 +Phosphatase modulator 0.519397520941224 1.4925229043934851 0.1355621173516565 1.0 0.4103817325853592 10 Q01105,Q5H9R7,Q15257,Q92688,Q99733,Q9BTT0 6 +Cysteine protease 0.4022355955481658 1.4768464036945386 0.1397168145034109 1.0 0.4142628565340975 46 P55210,Q96K76,P17655,Q14694,P27708,Q9Y4P1,P51784,Q06203,O60343,P49915,Q06210,P45974,P08243,Q96FW1,Q96RU2,P40818,Q9UPT9,Q14790,Q6GQQ9,P55212,O94966,P17812,P42574,Q8TC07,Q01804 25 +Other small molecule kinase 0.6367397133528931 1.4362904926407971 0.150919698248753 1.0 0.4341112864223425 5 P14618,P35790,O00764 3 +Receptor 0.4897413096103007 1.4241899355212728 0.1543914975350251 1.0 0.4355161227258061 27 Q8WTV0,Q9UQB8,Q567V2,Q13432,Q9ULC4,P20645,Q08AM6,Q9HAV4 8 +Translation factor 0.4856496809921851 1.41678690903784 0.1565452382406824 1.0 0.4379317653855621 28 P78344,P05198,O75153,Q9UJA5,P06730,P62495,Q9Y262,Q15056,O43432,P63241,P29692,O60573,O15371,Q04637,Q86TB9,Q14152 16 +Non-motor microtubule binding protein 0.5028188084187136 1.4055146962246328 0.1598682823263515 1.0 0.4394689823123912 19 Q14008,Q66K74,P13693,Q9UH99,Q15555,Q9BSJ2,Q96CW5,Q9BTW9,P78559,Q15691 10 +CDK family 0.5480353710456214 1.3907857977202702 0.1642903910542894 1.0 0.4424977486976049 8 Q00534,Q00535 2 +Histone deacetylase 0.6607316758850525 1.39024527628561 0.1644544090616515 1.0 0.4424977486976049 4 Q96EB6 1 +Protein phosphatase 0.4941638599977992 1.3413640986231343 0.1798022678842388 1.0 0.4641675558507482 12 Q8TF05,P63151,P30154,Q14738,P30307,Q9H0C8,P30153,O15355 8 +V-type ATPase 0.5099424137252788 1.3098797237334727 0.1902365274778343 1.0 0.4784474727806305 9 Q9Y5K8 1 +CK2 family 0.7618742446289175 1.250984416268213 0.2109401630898688 1.0 0.5046300953737225 3 P67870 1 +CK1 group 0.7552381979990577 1.2253280323250333 0.2204516505582574 1.0 0.5148133438877293 3 Q99986 1 +Calmodulin 0.4736274421820103 1.220175853867688 0.2223982182516954 1.0 0.5148133438877293 13 P80303,Q15293,Q6RFH5,Q14257 4 +Intracellular calcium-sensing protein 0.4736274421820103 1.220175853867688 0.2223982182516954 1.0 0.5148133438877293 13 P80303,Q15293,Q6RFH5,Q14257 4 +STE7 family 0.5652202150121006 1.1072880397921414 0.2681694136846213 1.0 0.5657122930166657 5 P36507,P52564,P45985 3 +Pyrophosphatase 0.7240967452970886 1.1053499403496876 0.2690079860924532 1.0 0.5659243621276789 3 Q9UKK9,Q9H2U2 2 +STE group 0.4430118526438951 1.053335066031015 0.2921874529659001 1.0 0.5843749059318002 11 P45985,Q13153,Q13043,Q13177,P36507,P52564,Q9H2G2 7 +Transcription cofactor 0.4323925394229776 0.9833212535377596 0.3254493530202245 1.0 0.6192015758248098 13 O00625,Q04727 2 +Nucleoside kinase 0.6905929647316575 0.977594087913753 0.3282751225438978 1.0 0.6203985096797611 3 Q9BZX2 1 +Kinase modulator 0.4320783890465166 0.975376716602588 0.3293734287359453 1.0 0.6205160130650398 18 Q93100,Q2TAL8,O95067,P20248,Q92616,P14635 6 +Chaperonin 0.4220345945444988 0.9425331133987722 0.3459197660412174 1.0 0.6355824242457505 10 P49368,Q99832,P50991,P40227,O75347,P17987,P48643 7 +TKL group 0.6799044490892912 0.9372724535284334 0.3486184287607636 1.0 0.6385473345116445 3 O43318,Q13546 2 +Phosphatase inhibitor 0.4791727661835123 0.936051979928529 0.3492464254186771 1.0 0.6388294226090947 7 Q01105,Q92688,Q99733,Q9BTT0 4 +Guanyl-nucleotide exchange factor 0.6646940622662886 0.8803688624225181 0.3786595189040043 1.0 0.6655333088170978 3 Q96N67 1 +Rel homology transcription factor 0.6437742609734347 0.8032155933500068 0.4218501341944742 1.0 0.6967503633934516 3 Q00653,Q04206 2 +Microtubule binding motor protein 0.3948146889671391 0.7655941369060499 0.4439178341840017 1.0 0.7095959319153361 15 Q99661,Q15058,P33176,Q96Q89,P52732,O60333 6 +Non-protein kinase 0.3948783191790614 0.7613322287529269 0.4464586552907372 1.0 0.7104281769709317 19 Q13572,Q9BZX2,P14618,P00568,P35790,P17858,Q8TBX8,P04183,O00764,P42356,O00443 11 +MAPK family 0.6290758967998564 0.7499379847854124 0.4532920558272821 1.0 0.7175140568608892 3 P28482 1 +Unclassified protein 0.3925711967034861 0.7480130832251789 0.4544522660709034 1.0 0.7177342721846113 18 P51570,P08237,P22392,P15531,P11908,Q9NVE7,P12277,Q01813,O75569 9 +Writer 0.3941481551798578 0.6968434113036951 0.4859007951650418 1.0 0.7489048048197504 9 Q99873,O14744,P26358 3 +CDK4 subfamily 0.8337313432835844 0.6944885849369713 0.4873758570322364 1.0 0.7494228678037337 2 Q00534 1 +SRPK family 0.8295522388059742 0.6814935628204518 0.4955592385422041 1.0 0.755524994149997 2 P78362 1 +SLC25 family of mitochondrial transporters 0.3791555181970258 0.6762752422439805 0.4988659085437044 1.0 0.7578164629425603 21 Q70HW3 1 +Cellular structure 0.3019579967332611 0.6337310140130654 0.5262563811168726 1.0 0.7770572315309143 111 P47756,P68371,Q7Z460,Q15555,Q6IBS0,Q9BUF5,Q96Q89,P78559,P47755,O60333,P57737,O00401,Q14008,P13693,Q9UH99,P35611,Q96CW5,P33176,Q9BTW9,P35241,Q99661,Q66K74,Q99439,P04350,Q9BSJ2,P07437,Q9UEY8,O43237,Q9NZ32,Q03001,Q15058,O75351,O43264,Q13885,P63172,Q15691,P15311,P52732 38 +Intracellular chloride channel (clic) family 0.8089552238805977 0.6186039477414612 0.5361773005493653 1.0 0.7823282060378152 2 O00299 1 +Immune response 0.4229836163079329 0.5968216320762075 0.5506264737371662 1.0 0.788300204271707 6 Q6AI08,Q6P2E9,P78318 3 +IKK family 0.8000000000000008 0.591907822139759 0.5539123155465351 1.0 0.7904777644739984 2 Q9UHD2 1 +Metalloprotease 0.3238176401197015 0.5769549391421246 0.5639698959356862 1.0 0.7970371603645666 40 O43847,Q9BPU6,Q92905,Q9NY33,P55786,P20839,P52888,O95630,O00487,Q7L5N1 10 +Exodeoxyribonuclease 0.793432835820901 0.5725998452534589 0.5669156645179687 1.0 0.7983719009664506 2 Q9UQ84 1 +VRK family 0.7898507462686589 0.5621680566860835 0.5740015230099551 1.0 0.8015507700536103 2 Q99986 1 +Ligase 0.2559768060662859 0.5500771482046967 0.5822664596939082 1.0 0.8059287901452807 77 Q7Z6Z7,Q93034,Q9NT62,P22314,P22681,P30520,Q13619,P26639,Q9UBT2,P68036,P07814,P48506,P47897,P41252,Q13617,P18858,Q9NSD9,Q96I59,O43776,O95376,Q13564,O95352,P11586,A0AVT1,O94822,P49589,P48507 27 +PKN family 0.7820895522388105 0.5398164064803311 0.5893236514081743 1.0 0.8102355971736873 2 Q16512 1 +Lipid kinase 0.404313862445272 0.519109151505667 0.603684626909645 1.0 0.8185964979667524 6 P42356 1 +Dehydrogenase 0.230286440445069 0.5137973900885189 0.6073936528488599 1.0 0.8205776591831401 58 Q8N4Q0,Q8N8N7,Q9P0J0,P49419,Q96CU9 5 +HDAC class III 0.7492537313432872 0.449378486729705 0.6531586478045197 1.0 0.8444636929335396 2 Q96EB6 1 +Phosphatase 0.3099110489269691 0.3917326355571919 0.6952557736808449 1.0 0.8649703316430323 34 Q08623,Q8TF05,P63151,Q9H0R4,Q9BY32,P33316,Q9NPH0,Q14738,P30307,Q5TFE4,Q13614 11 +BUB family 0.7140298507462719 0.3608084868595432 0.7182426179856931 1.0 0.8778239217304994 2 O60566 1 +Enzyme modulator 0.268039403523685 0.2878855348675147 0.7734343599027975 1.0 0.8982158898939059 120 O00410,Q9P0V9,Q15369,P60953,Q96CX2,O95067,P46940,Q96P16,O14737,Q7L576,Q93100,Q96N67,Q9NTK5,O43242,Q15436,Q9UHD8,O00429,P55036,P46379,Q96D71,Q15382,Q96BK5,P49407,Q01105,P21359,O15397,Q9Y263,Q5TAQ9,Q5H9R7,Q15257,Q14141,P60983,Q2TAL8,O95163,P55060,P20248,Q96P70,P30086,Q92616,Q9UNN8,Q99733,P50570,Q9H4M9,O95373,P43487,P04080,O75909,Q92688,P14635,Q14C86,Q13200,Q9BTT0 52 +MLK family 0.6797014925373193 0.2841978029804801 0.7762587990507932 1.0 0.898467397694555 2 O43318 1 +Aminoacyl-tRNA synthetase 0.2921707923997285 0.2728780469214076 0.7849469623392058 1.0 0.8997863143029668 18 Q96I59,O43776,P49591,P41250,P49589,P41252,P23381,Q9NSD9 8 +STE20 family 0.328104305842778 0.2502318791215071 0.8024080333067667 1.0 0.9079877884705396 6 Q9H2G2,Q13153,Q13043 3 +Acyltransferase 0.2847969788970227 0.241253689394454 0.8093585013808293 1.0 0.9079877884705396 9 Q92696,P24386 2 +PAKA subfamily 0.653731343283587 0.2332686268203915 0.8155528188200509 1.0 0.9079877884705396 2 Q13153 1 +Major histocompatibility complex antigen 0.4543011954981751 0.2299862101166433 0.8181024852607255 1.0 0.9079877884705396 3 Q6P2E9 1 +Small GTPase 0.2801627975553386 0.2253765233824161 0.8216863734830406 1.0 0.9079877884705396 26 O15397,Q9P0V9,P50570,O95373,Q14141,P60953,O00429,Q9UHD8,P55060,Q15382,Q96P70 11 +Nuclease 0.2593935316509805 0.222266138702618 0.824106710225164 1.0 0.9079877884705396 40 Q9Y2L1,Q9UQ84,Q5JSZ5,Q8NHU6 4 +Protein methyltransferase 0.2869936025882033 0.2093756066270457 0.8341550338391683 1.0 0.9079877884705396 8 O14744,Q99873 2 +Extracellular structure 0.2992958939717821 0.2071925755198767 0.8358594653890314 1.0 0.9079877884705396 7 Q9Y2T2,Q32P28 2 +Chaperone 0.2568135205786594 0.1952370164571543 0.845207401662607 1.0 0.9079877884705396 38 P31946,O00170,Q15813,P27348,P63104,P08238,O75347,P49368,Q99426,P50991,P40227,Q14203,Q99471,P17987,O75607,Q99832,P07900,Q5SW79,P48643 19 +Ubiquitin-protein ligase 0.2668882188748268 0.1931234831118855 0.8468622619747346 1.0 0.9079877884705396 18 Q13616,Q13619,Q9HB71,Q7Z6Z7,Q93034,O94822,O95376,Q13617,Q86UK7 9 +Reductase 0.2624272988276985 0.1839588646647946 0.8540457253711407 1.0 0.9079877884705396 17 Q15392,P23921 2 +Enzyme 0.1756265506786971 0.1796758318741438 0.8574070680091799 1.0 0.9079877884705396 680 Q08623,P11310,Q05639,Q9BV86,P55210,Q8N4Q0,P17655,P25205,Q7Z6Z7,Q9NPH0,Q9BXJ9,Q9Y4P1,P51784,Q9NW08,Q9UQ84,O00487,P48147,Q9H4L7,Q15392,Q9BPU6,P26639,P33316,P46199,Q13126,P46063,O60942,Q96BP3,Q96AE4,Q92620,Q96RU2,Q13617,P18858,Q9BY44,Q9UPT9,Q5JSZ5,Q9UKG9,Q8IX18,Q9Y570,Q08J23,Q86TI2,P24386,P55212,P55786,O00330,O95376,P13639,Q96CU9,O95352,Q5VZE5,Q8N8N7,P17812,O94822,A3KN83,P52888,P49419,Q01804,P34949,P00813,O75880,Q9P0J0,Q8NHU6,Q5TAX3,P49005,P23921,P22681,Q8TF05,Q6P158,Q06210,P30046,Q5TFE4,P49903,P40818,O43847,O00154,Q14790,P08397,Q01433,Q00796,Q9Y2L1,Q9UBP6,Q9H0R4,Q9BV10,P48634,Q8TC07,Q96K76,Q9NT62,Q14CX7,Q7Z478,Q9BUI4,Q9BSD7,Q9NR45,Q9NY33,Q9UBT2,P68036,O14929,P08243,P29372,P31939,P49642,P00374,P49327,Q13057,Q13564,Q8NE71,Q92905,Q96C86,Q9UKK9,Q9Y450,O95630,O75182,P63151,P53004,Q96C23,P11413,O14802,O60343,O60841,P00492,P19174,P42694,P53396,Q96FW1,Q9HAU5,Q9NRN7,Q9NSD9,O43776,P20839,P30307,Q7L5N1,Q9BWD1,Q9BY32,Q9H2U2,Q9NUW8,Q14738,P49589,P06737,P30566,P42574,Q13614 139 +Nucleotidyltransferase 0.2565842661385479 0.1654189674527397 0.8686142254609428 1.0 0.9079877884705396 32 Q9BUI4,O14802,Q5TAX3,O60942,P49005,P49642 6 +Non-motor actin binding protein 0.252409707489424 0.1476799036039097 0.8825953923151011 1.0 0.9155778386674776 28 P47756,Q9NR12,Q99439,P35611,Q9UJU6,Q6IBS0,Q9UEY8,Q16658,Q96HC4,P55196,P47755,P57737 12 +CAMK group 0.2461860604247648 0.1438653617131269 0.8856067884403607 1.0 0.9159952566711572 9 Q13555,Q9Y478,Q7KZI7,O14936,Q13131,O96017,P54619,Q14012 8 +G-protein 0.2406788007799147 0.1364115890517092 0.8914959125787898 1.0 0.9194642018948952 36 O15397,Q9NTK5,Q5TAQ9,Q15382,Q96P70 5 +Hydrolase 0.2227726626909671 0.1283653530508081 0.8978598485413813 1.0 0.9223389875473782 108 Q08623,Q05639,P62191,P00813,A6NDG6,P46926,O75182,P63151,P43686,Q9NPF4,Q9NPH0,Q7Z2Z2,Q9UG63,Q15181,Q8TF05,O60841,P19174,P33316,P46199,O15355,Q969T7,P29372,Q5TFE4,O00178,Q70Z53,O00154,Q9Y570,P08397,Q01433,P30307,P49327,P13639,Q5T9A4,O95336,Q8NE71,Q9H0R4,Q9BY32,Q9H2U2,Q96C86,Q9NUW8,P30154,Q9NUQ8,Q9UKK9,O95861,Q9Y450,Q14738,Q9BW91,Q01968,Q14204,P62195,Q13614 51 +Epigenetic regulator 0.234462598666006 0.1105123582560222 0.9120030494313572 1.0 0.9291774187832756 28 Q96EB6,Q7LBC6,Q16637,Q6PL18,O14744,P26358,P25440,O60678,Q99873 9 +Polymerase 0.2266836174431116 0.1004309162483244 0.9200022262223448 1.0 0.9363449077605868 23 Q9BUI4,P49005,O14802,P49642 4 +Phosphodiesterase 0.3564647547058698 0.0862756526044272 0.9312472927023944 1.0 0.945576220592078 3 Q9NUW8 1 +HDAC class I 0.5194029850746352 0.0711479426764495 0.9432800120817968 1.0 0.9550483807546024 2 Q13547 1 +Lysine-specific demethylase 0.5119402985074711 0.0666585493748917 0.9468535336861992 1.0 0.9582066935625324 2 Q8NB78 1 +Antibacterial response protein 0.5065671641791132 0.0636635655706233 0.9492381163312932 1.0 0.9601593602392277 2 Q9NUQ3 1 +Actin family cytoskeletal protein 0.1545832340360446 0.0477786069916846 0.961892686228664 1.0 0.969705479188954 50 P47756,Q9NR12,O00401,Q9NZ32,Q99439,P61160,P35611,Q6IBS0,P35241,Q9UEY8,O15145,P61163,Q96HC4,P55196,Q9UM54,P15311,P47755,P57737 18 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6e2970d6f4eae49786aaaca05cf6ee30f0af9083 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein sigma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit beta-1", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 2B", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "ATR subfamily", "AUR family", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 2, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Alpha-tocopherol transfer protein-like", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arsenite methyltransferase", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-arrestin-1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional coenzyme A synthase", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CASP8-associated protein 2", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CRK7 subfamily", "CSK family", "CTP synthase 1", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-3", "Caspase-6", "Caspase-7", "Caspase-8", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 2 tau variant", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1A", "Coronin-1B", "Coronin-1C", "Coronin-7", "Coup transcription factor 1", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cystine/glutamate transporter", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication complex GINS protein PSF1", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 4", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity mitogen-activated protein kinase kinase 3", "Dual specificity mitogen-activated protein kinase kinase 4", "Dual specificity mitogen-activated protein kinase kinase 6", "Dual specificity protein kinase clk3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dynein light chain Tctex-type 1", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZFP91", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enolase-phosphatase E1", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Esterase", "Esterase OVCA2", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Follistatin-related protein 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GA-binding protein alpha chain", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock factor protein 1", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol 1,4,5-trisphosphate receptor type 2", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Katanin p60 ATPase-containing subunit A1", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LIM domain-containing protein 1", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MAST family", "MAX gene-associated protein", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA epimerase, mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 5", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "Na+/K+-ATPases", "Nardilysin", "Neural Wiskott-Aldrich syndrome protein", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nf-kappa-b essential modulator", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor NF-kappa-B p100 subunit", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoplasmin-3", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Opioid growth factor receptor", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylase b kinase regulatory subunit beta", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable asparagine--tRNA ligase, mitochondrial", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Protein AATF", "Protein BUD31 homolog", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRA10AC1", "Protein FRG1", "Protein LSM14 homolog B", "Protein NDRG1", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein VAC14 homolog", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase c beta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase 1L", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab proteins geranylgeranyltransferase component A 2", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor expression-enhancing protein 6", "Receptor-interacting serine/threonine-protein kinase 1", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoC", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Riboflavin kinase", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC35 family of nucleotide sugar transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC61 Molybdate transporter family", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-10", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine-protein kinase atm", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase atr", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tbk1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-dependent multivitamin transporter", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 7", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptosomal-associated protein 23", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 6", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 4", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "Tyrosyl-DNA phosphodiesterase 1", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 J2", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit G 1", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuole membrane protein 1", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "ZZ-type zinc finger-containing protein 3", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger HIT domain-containing protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "AMPD2", "ANAPC1", "ANGEL1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOL2", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "B3GAT3", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CBL", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CEP170", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHM", "CHML", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTSA", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCPS", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENOPH1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXC1", "FOXRED1", "FRA10AC1", "FRG1", "FSCN1", "FSTL1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GIPC1", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKG", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS2", "MASTL", "MAT2A", "MBNL1", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "MED21", "METAP1", "METTL1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGA", "MGAT5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL19", "MRPL20", "MRPL21", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NARS2", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCEH1", "NCL", "NCOA5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEK9", "NF1", "NFKB2", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OGFR", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OVCA2", "OXA1L", "OXCT1", "OXSR1", "P3H1", "PACSIN2", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNGTT", "RNH1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A11", "S100A13", "SAE1", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SNAP23", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOD2", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDP1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM38B", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2L3", "UBE4A", "UBIAD1", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WASF2", "WASL", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR4", "WDR74", "WDR82", "WNK1", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFP91", "ZFR", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF598", "ZNF644", "ZNHIT2", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AASDHPPT", "ABCF1", "ABCF2", "ABCF3", "ACADM", "ACAT2", "ACLY", "ACOT7", "ACP6", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADD1", "ADD3", "ADSL", "ADSS", "AFDN", "AIP", "AK1", "AKT2", "ALDH7A1", "ALG12", "AMPD2", "ANP32B", "ANP32E", "AP3M1", "ARIH2", "ARPC3", "ARRB1", "ASNS", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP6V1D", "ATR", "AURKA", "BAG6", "BAIAP2", "BLVRA", "BPNT1", "BRD2", "BUB1", "BUB1B", "CACYBP", "CAD", "CAMK1", "CAMK2G", "CAPN2", "CAPZA2", "CAPZB", "CARS", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CDC25C", "CDC42", "CDK12", "CDK4", "CDK5", "CDK6", "CEP170", "CHEK2", "CHKA", "CHM", "CHUK", "CKAP5", "CKB", "CLASP1", "CLIC1", "CLK3", "CLUH", "CMPK1", "CNN2", "COASY", "COPS5", "COPS6", "CORO7", "CROT", "CSE1L", "CSK", "CSNK2A2", "CSNK2B", "CSTB", "CTPS1", "CUL1", "CUL2", "CUL4A", "CUL5", "CYFIP1", "DBNL", "DCAF8", "DCPS", "DCTN1", "DDT", "DHCR24", "DHFR", "DHX29", "DHX38", "DHX40", "DHX57", "DIS3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPP3", "DPP9", "DPYSL5", "DST", "DUT", "DYNC1H1", "DYNC1LI2", "DYNLT1", "EDC4", "EEF1A2", "EEF1D", "EEF2", "EFL1", "EHD1", "EIF2A", "EIF2S1", "EIF3A", "EIF3D", "EIF3L", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF5B", "ELOC", "ELP1", "EPRS", "ETF1", "EXO1", "EZR", "FARSB", "FASN", "FOXRED1", "FRA10AC1", "FSCN1", "FUBP1", "G6PD", "GALK1", "GALM", "GAPVD1", "GARS", "GCLC", "GCLM", "GCN1", "GFPT1", "GMFB", "GMPS", "GNPDA1", "GTPBP1", "HAT1", "HBS1L", "HDAC1", "HDHD2", "HEATR6", "HELZ", "HMBS", "HPRT1", "HSP90AA1", "HSP90AB1", "HUWE1", "IARS", "IGBP1", "ILKAP", "IMPDH1", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "ITPA", "ITPK1", "KCTD12", "KDM1B", "KDM3B", "KIF11", "KIF14", "KIF1B", "KIF20B", "KIF2C", "KIF5B", "LIG1", "LTN1", "M6PR", "MAP1A", "MAP1S", "MAP2K2", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARK2", "MCM3", "MCTS1", "METTL1", "MPG", "MPI", "MPV17L2", "MTAP", "MTHFD1", "MTIF2", "MTMR2", "MYO6", "NAA15", "NAA25", "NAA35", "NAE1", "NAGK", "NANS", "NAP1L4", "NARS", "NARS2", "NDUFA13", "NEK9", "NF1", "NFKB2", "NME1", "NME2", "NPEPPS", "NPM3", "NRDC", "NSUN2", "NT5C3B", "NT5DC1", "NTMT1", "NTPCR", "NUCB2", "NUDT5", "NUDT9", "OCRL", "OLA1", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "P3H1", "PAK1", "PAK2", "PANK4", "PATL1", "PBK", "PDCD5", "PDHX", "PDLIM5", "PDLIM7", "PDXK", "PEBP1", "PFDN5", "PFKL", "PFKM", "PFKP", "PGK1", "PGLS", "PGP", "PHKB", "PI4KA", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLK1", "POLD2", "POLR3A", "POLR3B", "POLR3C", "PPA1", "PPA2", "PPAT", "PPM1G", "PPME1", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PPWD1", "PREP", "PRIM1", "PRKAA1", "PRKAB1", "PRKACA", "PRKAG1", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPS2", "PRRC2A", "PRRC2B", "PSMC1", "PSMC4", "PSMC5", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PTGR2", "PTPA", "PUDP", "PYGL", "QARS", "QRICH1", "RABGGTA", "RANBP1", "RCN1", "RCN2", "RDX", "RECQL", "RELA", "REPS1", "RHEB", "RIPK1", "RNGTT", "ROCK1", "ROCK2", "RPRD1A", "RRM1", "SARS", "SBNO1", "SCARB1", "SCO1", "SEC23A", "SEPHS1", "SEPT10", "SEPT6", "SEPT9", "SET", "SIN3B", "SIRT1", "SLC25A26", "SLK", "SMARCAD1", "SMN1*", "SORD", "SRPK1", "SRPK2", "STAMBP", "STK4", "SUN2", "TARS", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCP1", "TDP1", "TDRD7", "THOP1", "TK1", "TLE4", "TPT1", "TRMT6", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TWF2", "TXLNG", "UBA1", "UBA2", "UBA6", "UBE2L3", "UCK2", "UNC119", "UPF2", "USP10", "USP11", "USP19", "USP22", "USP28", "USP47", "USP5", "USP8", "VAC14", "VPS4B", "VRK1", "VRK3", "WARS", "WASL", "WDR74", "XPO5", "YWHAB", "YWHAQ", "YWHAZ", "ZADH2", "ZCCHC11", "ZNF598", "ZW10"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..577277ffe210c7e974817cc6f2273abdcf58fb6c --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tchem"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a93365dd1512dcbcb81afdf985da2b7b44e54782 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3665bcda0711dc8010f9382b3e263378e529451bbbe9fd16e2341913e81faa9f +size 134274 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..96aea3ac9d64b12a1d5bf62175a7b993952080fc --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cfdf9a3a317424542d590d131b1fa4e464adb357ea3d689f7486bce2e2dc0ec +size 84073 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..526c24867a9a6edf32a997d191bdf2bb067ee935 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 837.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a0bbe508c7db67886e27fa648fd38492de1a298c --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..db0e38ee9a68975823acfdc6c4c520eba6c0e122 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tchem 0.2449846171828178 0.1012629348651699 0.9193417385998456 0.9999576751501612 1.0 342 Q05639,Q03164,P55210,Q00535,P17655,O60502,P54136,P48147,O60725,O75874,P14618,P26639,P33316,Q13126,Q96SB4,P18858,P78362,Q9Y263,Q9Y570,P31751,Q86TI2,P55212,P55786,O60678,P04183,P13639,P13807,P14735,Q13535,Q96B36,P26572,P50570,P45985,P30519,P26640,P42356,P34949,Q9P2J5,Q9NQW7,P27708,Q16512,O96017,O15111,P30520,Q06210,P07099,P48506,P47897,P45974,P41252,Q08209,Q14790,Q15257,Q13432,Q01433,Q00796,P43490,P35790,P42858,P49761,P41440,Q96K76,P78417,Q8WTV0,O43318,P08243,P29372,P31689,P31939,P40763,P19784,Q96EB6,Q4J6C6,Q15126,P20248,P48449,P49327,Q06124,Q13564,Q9GZT9,P13674,P14635,P27695,P31946,P63151,P41240,Q6PL18,Q00653,P11413,P09960,P00492,P19174,P53396,Q99873,Q9H4A4,O15357,O14965,P30307,P28482,Q9NUW8,Q9UHD2,O14744,P06737,P42574,P28161,P50579,P53602 107 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e5132eb86caa47bd4b9def329cd20eedf3854eaf --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANKRD46", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf174", "C1orf198", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "C5orf24", "C8orf33", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NEMP1", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", 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biosynthesis 49 96 2.2744215450029763 0.0229406532702909 35.86165048543689 91.69660194174756 -0.6847256109282409 0.5198664727151647 13.42066893107237 4.841937358665325 1.1443696295547725 0.3620297514137219 0.4354539614343957 0.3227766118505818 0.0286909198771697 1.714795536481918e-06 +Purine biosynthesis 7 10 2.225076818995401 0.0260760816234768 5.609223300970874 9.57766990291262 -0.5956690698419117 0.4049019913941552 2.4976129144695394 0.4988203635714793 1.0719792910136363 0.3162446040890186 1.0 1.0 0.2532529321952443 0.0019884945269669 +Ubl conjugation pathway 75 148 2.10143831204038 0.0356025077860169 39.72330097087379 126.52184466019418 -0.3906356571472509 0.5381051627839192 16.022015823401837 22.367886318219735 1.2547606520431642 0.3543570936569808 0.1013845078571837 0.0302798951839001 0.061219799533638 0.0048404736512048 +Nucleotide metabolism 7 12 2.0659571238664407 0.0388325282643107 2.825242718446602 9.657766990291265 0.1031324982165795 0.4462534906167557 2.086373657371837 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P49770,Q05639,P26641,Q9P2J5,Q15056,Q14232,Q9ULC4,P29692,Q7Z2Z2,P54136,P41567,Q14152,Q7Z478,O60841,P26639,P62495,P46199,P07814,O43432,P47897,P41252,O15371,Q96E11,P54577,Q9NSD9,Q9BY44,P78344,Q6PKG0,Q96I59,O43776,P55010,Q8TEQ6,Q13144,Q9Y262,P41214,P63241,P13639,Q04637,Q14240,P05198,Q9NR50,Q9BTE6,P06730,P26640,Q9Y450,P49589,O60573,O75821,Q9Y285 49 +Purine biosynthesis 0.6521349816301546 2.225076818995401 0.0260760816234768 0.9899224371226756 0.302346012732632 10 Q06203,P30520,P49915,P20839,P30566,P31939,O15067 7 +Ubl conjugation pathway 0.4748790900514411 2.1014383120403797 0.0356025077860169 0.998177965506197 0.302346012732632 148 Q9Y3I1,Q5T4S7,Q15369,Q96K76,Q7Z6Z7,Q93034,Q9NT62,Q14694,Q14258,O60826,Q96S82,Q9Y4P1,P51784,P22314,Q96DY7,O00487,Q14999,P22681,Q9UPN9,Q13309,Q13619,Q9NR09,Q9Y314,O15344,P68036,Q9UBT2,P49427,P61081,O95260,P45974,P61960,Q96FW1,Q8IWV7,Q96RU2,Q86VP6,Q13617,P19474,P61962,Q15386,Q8N806,P40818,Q9C0C9,Q9UPT9,Q9UII4,Q9ULT8,Q5TAQ9,Q8TBC4,Q9Y4B6,Q13618,Q6GQQ9,O95071,P61086,Q9UJX4,Q05086,Q16763,O95376,Q9Y5K5,Q13564,Q8TAT6,O95352,Q7Z7E8,Q86UV5,O95628,O94966,Q96BN8,O75150,Q9NUQ7,A0AVT1,O94822,Q93008,Q5VTR2,Q96JP5,O95630,Q14527,Q01804 75 +Nucleotide metabolism 0.6221381671821296 2.0659571238664407 0.0388325282643107 0.9989836640834132 0.302346012732632 12 Q08623,P00813,Q9BY32,P15531,P33316,Q01433,P22392 7 +DNA replication 0.3865219491787027 2.009426379988942 0.0444919349241665 0.9996362708240204 0.3225665282002077 54 P28340,Q9UBD5,P35244,P25205,Q9BTE3,Q07864,P18858,P49005,P23921 9 +DNA excision 0.9432666467602272 1.9478563174186647 0.0514321578855851 0.999897693992982 0.3249216294177321 3 Q9UQ84,P49005 2 +mRNA capping 0.7678839685216082 1.8604229993930264 0.0628257032130235 0.9999875047713868 0.3549180401831335 4 O60942 1 +Glycogen biosynthesis 0.7575809783398497 1.8158190078964629 0.0693981405225026 0.9999963278418166 0.3549180401831335 4 P13807,P31751 2 +Purine salvage 0.713210440381216 1.7846822143546643 0.0743128774316495 0.9999985385812866 0.3549180401831335 5 P00492,P07741,Q13126 3 +Glycogen metabolism 0.5922719448371767 1.7532995937773714 0.0795505952134609 0.9999994555145332 0.3549180401831335 9 Q93100,P31751 2 +Coenzyme A biosynthesis 0.8851006029839279 1.726798438197465 0.0842038690951887 0.9999997745802518 0.3662868305640709 3 Q9NVE7 1 +Biological rhythms 0.3949314366790647 1.7042184197666006 0.0883402892308771 0.9999998974582688 0.3749075689310395 50 Q00653,Q96EB6,Q03164,Q00535,O00429,Q06210,O14744,Q05086,O75116,P43490,O95352 11 +Pyrimidine biosynthesis 0.6983273596176711 1.5565425177396734 0.1195791404846766 0.9999999997622524 0.4728811464621303 4 P11172,P27708,P17812 3 +tRNA processing 0.4550874973689781 1.5021789808283086 0.1330508916794106 0.9999999999837488 0.5032794598308141 38 Q9UBP6,Q6IA86,Q9UJA5,O60294,Q08J23,O95163,Q99575,Q92499,O15091,O75818,Q2VPK5,Q7Z4G4,Q7Z2T5,P57081,Q6P1R4 15 +DNA condensation 0.5538783947377324 1.4210747348337778 0.1552950340607402 0.9999999999998236 0.5514558352360979 8 Q6IBW4,P42695,Q15021,Q15003,Q9NTJ3,Q9BPX3 6 +Oogenesis 0.6238736395352603 1.3771165658642155 0.1684762117705283 0.9999999999999886 0.5753037459674865 5 Q9H6S0 1 +Nucleotide biosynthesis 0.6237701389204409 1.376640212675816 0.1686235117490908 0.9999999999999888 0.5753037459674865 5 P11908,O60256,Q14558 3 +Translation regulation 0.3687077441571912 1.364779592873098 0.1723223346418154 0.9999999999999948 0.5766170428399209 49 Q9BX40,P61221,Q92600,Q06787,P14618,P27635,O43432,P07814,Q96PU8,P78344,Q9BY44,Q6PKG0,P31751,Q8TEQ6,Q9UIV1,Q04637,Q92616,P05198,P06730,Q9Y450,O60573,A5YKK6 22 +Cilium biogenesis/degradation 0.48342022067195 1.301692955247025 0.1930213687724224 1.0 0.6098805452834981 21 Q9H4M9,O14965,Q9Y5Y2,Q9Y5K8,Q13618,P10155,Q6IBS0,Q01968,Q16513,Q3SYG4 10 +GMP biosynthesis 0.7563451776649719 1.2296062767997635 0.2188445784099848 1.0 0.6242451908743829 3 P20839,P49915 2 +Myogenesis 0.5365752747320258 1.219598282416013 0.2226171978539781 1.0 0.6247643939772936 7 Q96EB6,P85037,P51114,Q14331 4 +Glycolysis 0.4592870900178111 1.133585595282263 0.2569684181427607 1.0 0.6742711684416841 16 P04075,P09972,P08237,P14618,P17858,Q01813,P00558,P18669 8 +Differentiation 0.3276772261140204 1.110181450925552 0.2669208441938142 1.0 0.6742711684416841 94 Q7Z6Z7,Q8NHU6,P85037,Q9BXJ9,Q9H6S0,Q96N67,Q14997,P46379,P51114,Q96PU8,P16949,Q96TC7,Q96EK7,Q96SB4,Q92974,P78362,Q9BW83,Q96EB6,Q99426,Q15645,Q08J23,A1X283,P43034,Q6P6C2,P15531,Q9H8V3,Q00534,Q13501 28 +Antiviral defense 0.409229114158418 0.9244283782286082 0.3552633252848793 1.0 0.8028028389554417 29 Q9UII4,Q9BUI4,O14802,Q9NUD5,Q9UHD2,Q9Y3Z3,Q14258,Q9NW08,Q13309,Q7Z7L1 10 +DNA repair 0.3322160433034979 0.8756214611760786 0.3812358544091316 1.0 0.8314966843340994 117 Q96K76,P54277,Q7Z6Z7,Q9BUR4,Q9Y3Z3,P18074,Q92547,P49005,Q9UQ84,Q9H4L7,P35244,Q99504,Q14997,P09429,Q96FW1,Q96RU2,P29372,P18858,P28340,Q92759,O95071,P20585,P52701,Q13535,Q86WJ1,Q96T76,Q9NUW8,Q07864,Q9Y620,P27695 30 +DNA damage 0.3480924987987966 0.8451739102570953 0.3980137467436719 1.0 0.8343902642578184 135 Q96K76,P54277,Q7Z6Z7,Q9BUR4,Q9Y3Z3,Q9ULC4,P18074,Q92547,Q06787,P49005,Q9UQ84,Q9H4L7,P35244,Q99504,Q14997,O60921,P09429,Q96FW1,Q96RU2,P29372,P18858,P28340,Q92759,O95071,P20585,P52701,P57081,Q7Z7L1,Q13535,Q86WJ1,Q96T76,Q9H993,Q9NUW8,Q07864,Q9Y620,Q96FZ2,P27695 37 +Spermatogenesis 0.3834471851469451 0.7129240831449611 0.4758927356311184 1.0 0.8430490114871164 24 Q9BW83,Q15645,Q6P6C2,Q14997,P46379,Q8NHU6,Q9H6S0 7 +Glyoxylate bypass 0.8370149253731343 0.7047510036442463 0.4809652047096029 1.0 0.8430490114871164 2 P48735 1 +Immunity 0.2814951081305019 0.7033357304635889 0.4818465486309811 1.0 0.8430490114871164 86 Q9NUD5,P41240,Q9Y3Z3,Q14258,P25786,Q9NW08,Q9UQ84,Q13309,O00743,Q14166,Q9BUI4,O14802,P46379,Q92499,P09429,Q96FW1,Q92974,Q9UII4,O15357,Q8IXJ6,Q6GQQ9,Q7Z7L1,Q96RS6,O95801,Q96BN8,Q9UHD2,O15347,P17812,Q13501,O75179,Q01804 31 +Glutathione biosynthesis 0.6128518191058854 0.6921964702271736 0.4888139550922399 1.0 0.8430490114871164 3 P48506 1 +RNA-mediated gene silencing 0.3637385813418937 0.5941030180672555 0.5524432124055842 1.0 0.902974723389408 22 Q5TAX3,Q9UIV1,O75569,O60573,Q9HAV4,Q9HCE1,Q06787,Q9UPY3,A5YKK6 9 +Vision 0.3721842318000923 0.5898703706246913 0.5552775597854405 1.0 0.902974723389408 9 Q3SYG4 1 +Sensory transduction 0.3721842318000923 0.5898703706246913 0.5552775597854405 1.0 0.902974723389408 9 Q3SYG4 1 +Mitosis 0.3041371801743026 0.5218888388830657 0.601747729774371 1.0 0.9200371625744896 125 Q6NUK4,P52732,Q7Z460,Q9HBM1,Q9H6H4,Q69YH5,Q9BTE3,O95067,P53350,P42695,Q9BT25,Q8TD19,Q15555,Q96Q89,Q6P1K2,O96017,P50748,Q9Y6G9,O00401,Q14008,Q9NXR7,O60566,Q9NR09,Q9NRZ9,O43684,Q92974,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,Q7Z4H7,Q8IXJ6,Q13618,Q08J23,O14965,Q9UJX4,Q14203,P20248,Q8IX90,P30307,Q9NTJ3,Q29RF7,Q7Z5K2,Q99741,Q9HC35,P43034,O75935,Q99986,Q9UJX5,Q9Y5K6,O95347,O75909,P63172,Q93008,Q15021,Q15003,O43264,Q14204,Q15691,P14635,Q9BPX3 62 +Cell shape 0.4011225879797205 0.5061950998935949 0.6127196945866074 1.0 0.9200371625744896 6 Q96AC1,P35579,P15311 3 +Phagocytosis 0.4395089594013213 0.4602278745117026 0.6453526651747332 1.0 0.959755245644475 4 Q14185 1 +Molybdenum cofactor biosynthesis 0.5389668557778404 0.4488463599510308 0.6535424930329075 1.0 0.9636982524383552 3 Q9NZB8,Q9Y697 2 +Meiosis 0.3278776556502019 0.4276619937387229 0.6688972241847524 1.0 0.964188144846476 15 Q9UH99,Q9H6S0,Q9UQ84 3 +Innate immunity 0.2223611776639121 0.3611186852835031 0.7180107255885539 1.0 0.986470439102037 66 Q9NUD5,Q9Y3Z3,Q14258,Q9NW08,Q13309,O00743,Q14166,Q9BUI4,O14802,Q92499,P09429,Q92974,Q9UII4,Q8IXJ6,O95801,Q96BN8,Q9UHD2,O15347,O75179,Q01804 20 +Wnt signaling pathway 0.3092045416156733 0.3487151554960607 0.7273031652203623 1.0 0.98867774022143 29 P19784,Q96BN8,Q96C57,P67870,Q04727 5 +ER-Golgi transport 0.2404107594715933 0.3016092435634238 0.7629499606296146 1.0 1.0 50 P53621,Q8N6T3,P53992,P54920,Q7Z392,Q9UBF2,O15027,Q9Y6B6,Q15436,P61923,O95486,Q13618,Q96RQ1,O95487,P24390,P53618,Q9NR31,P48444,Q92734,Q9Y678,O95070,O43264,P35606,O94979 24 +Autophagy 0.2833789937312145 0.2553168297536659 0.7984784023292189 1.0 1.0 32 Q9NT62,P09429,Q9Y4P1,Q9H269,O95352 5 +Carbohydrate metabolism 0.2847849886602691 0.2411643717329621 0.8094277232605942 1.0 1.0 26 P11413,Q93100,O60701,Q96C23,P31751,P06737,O95394 7 +Hearing 0.6394029850746321 0.2078982628408757 0.8353084055917512 1.0 1.0 2 O60610 1 +Neurogenesis 0.222599966714875 0.160145684914155 0.8727663141981628 1.0 1.0 47 Q96N67,Q9Y263,Q99426,P15531,Q14155,P16949,Q9P265,Q06787 8 +Chromosome partition 0.2416899163208532 0.1256717436395026 0.8999917698093816 1.0 1.0 23 Q96T76,O76071,P18074,Q6P1K2,Q96SB4,Q99661 6 +Viral RNA replication 0.5740298507462755 0.1172528215297658 0.906659710026515 1.0 1.0 2 Q15365 1 +DNA recombination 0.2327991384317373 0.1078633080627298 0.9141041231845894 1.0 1.0 26 P09429,P35244,P18858 3 +Cell division 0.2541577729627914 0.0958466025508433 0.9236424042249992 1.0 1.0 165 Q00535,Q9P0V9,Q6NUK4,P52732,Q7Z460,Q9HBM1,Q9H6H4,Q69YH5,Q9BTE3,O95067,P53350,P42695,Q9BT25,Q96CT7,Q8TD19,Q15555,Q96Q89,Q6P1K2,P50748,O96017,Q9Y6G9,O00401,Q14008,Q9NXR7,O60566,Q9NR09,Q9NRZ9,O43684,P11802,Q92974,Q8TEW0,P18858,Q99661,Q2NKX8,O43683,Q9H900,Q9P258,Q7Z4H7,Q8IXJ6,Q13618,Q08J23,O14965,Q14141,Q9UJX4,Q14203,P20248,Q8IX90,P30307,Q9NTJ3,Q16513,Q29RF7,Q7Z5K2,Q99741,Q9HC35,P43034,O75935,Q99986,Q9UJX5,Q9H8V3,Q9Y5K6,O95347,O75909,P63172,Q93008,Q00534,O75351,Q15021,Q15003,O43264,Q14204,Q15691,P14635,Q9BPX3,Q16763 74 +Angiogenesis 0.2075219810437858 0.095810607394157 0.9236709926375296 1.0 1.0 12 Q9BXJ9,Q96BN8 2 +Host-virus interaction 0.1701042941931264 0.0825737068276314 0.9341905087704524 1.0 1.0 261 P29083,P31946,O00629,Q15369,P61221,Q9P0J0,Q9BUR4,Q9Y3Z3,O60502,P85037,Q9UER7,P18074,Q14258,P51784,Q06787,Q13309,Q14999,Q14152,Q8WTV0,P19174,Q04323,P49720,Q92499,O43318,P61289,O60942,P09429,Q13617,Q96SB4,P28070,P40763,P49721,Q96EB6,Q01105,Q14790,Q9Y2T2,Q9Y4B6,O95071,Q05086,Q08AM6,P20248,P30307,P52701,Q9HAV4,P14735,Q14240,P28482,O75569,Q7Z5K2,Q7L5N1,Q92538,Q9UHD2,P28074,O75179 54 +Apoptosis 0.2200224811632085 0.0817028358980704 0.9348830231811602 1.0 1.0 130 Q03164,P55210,Q00535,Q9P0J0,Q96IZ0,Q9UER7,O14737,O60333,Q9NR09,P46379,O43318,P61289,Q96TC7,P19784,Q96EB6,Q66K74,Q14790,P31751,Q14185,P55212,Q13564,P28482,P42858,Q13501,P42574 25 +Protein transport 0.1690716581744719 0.0791174120068262 0.9369392341472148 1.0 1.0 246 O00629,Q2M389,Q9UID3,Q9NT62,Q96KP1,Q7Z3U7,Q9UBF2,O60826,Q9Y4P1,Q9Y3E0,P61970,Q9Y6D5,Q3SYG4,P57737,Q9Y6B6,Q9BW83,O15397,Q96T51,Q9Y2T2,Q9UIA9,Q96JB2,O60830,P55060,Q9Y5L0,Q13432,P63241,O60493,Q96P70,Q9HAV4,Q9H269,O95487,O95352,P24390,P53618,P60059,Q9H814,P48444,Q9H4M9,Q92538,Q9H8V3,Q14746,Q8TAG9,Q96D46,Q9Y5X3,Q9UJY4,O95070,P20290 47 +Cell cycle 0.2341567361065403 0.0776776728066608 0.938084454951264 1.0 1.0 238 Q00535,Q7Z460,P25205,Q9BT25,Q6P1K2,Q96DY7,P50748,O60566,P49427,P11802,P18858,Q99661,Q9H900,Q9UPT9,Q9P258,Q08J23,P43034,P36404,Q93008,Q14204,Q15398,Q9BPX3,Q9P0V9,Q9HBM1,Q9H6H4,O95067,Q9ULC4,Q96Q89,O96017,O00743,O00401,Q92974,Q8TEW0,P40818,Q2NKX8,Q7Z4H7,Q9UJX4,Q9NTJ3,Q16513,Q9HC35,O75935,Q00534,Q15021,Q15003,P63172,Q15691,Q8TCY9,P52732,Q16763,Q6NUK4,Q69YH5,Q9BTE3,Q96CT7,Q14008,Q9NR09,O43684,P61289,P19474,P19784,Q8TBC4,Q8IXJ6,Q13618,Q14203,P20248,Q13564,Q7Z5K2,Q99986,Q9H8V3,O95347,O75909,O75351,O43264,P14635,P53350,P42695,Q8TD19,Q15555,Q9Y6G9,Q9NXR7,Q9NRZ9,Q9Y3P9,O43683,P33991,Q13526,O14965,Q14141,Q8IX90,P30307,Q8TAE8,P28482,Q29RF7,Q14012,Q99741,Q9Y5K6 94 +Endocytosis 0.2088726718624816 0.0765890886628649 0.9389504394419566 1.0 1.0 34 P50570,Q96T51,P15531,O00429,Q9Y5X3,Q13432,Q14677 7 +Exocytosis 0.1928954365568189 0.0753065931676399 0.939970775791618 1.0 1.0 15 Q13153,Q8TAG9,Q15334,Q96KP1,Q12765,O00443 6 +Virus entry into host cell 0.3326366079426604 0.0685219066808998 0.9453701820480228 1.0 1.0 3 P63172,O00505 2 +Tetrahydrobiopterin biosynthesis 0.426865671641802 0.0376921922352584 0.9699331012684826 1.0 1.0 2 P61457 1 +Polyamine biosynthesis 0.3680597014925459 0.0321362998207217 0.9743633552799372 1.0 1.0 2 P19623 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..11aed85b2beef7af535e153fc2c7f3ffb508a44d --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "Cytoplasmic inwards viral transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Microtubular inwards viral transport", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine metabolism", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFTPH", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOL2", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARRB1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATR", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG3", "BAG6", "BAHD1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPV", "CERS1", "CERS2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG7", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS1L", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FRYL", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGPS1", "GHITM", "GINS1", "GINS3", "GINS4", "GLRX", "GMPR2", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INPPL1", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD5", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MALT1", "MANF", "MAP1S", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METTL1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MKI67", "MKRN2", "MLEC", "MMGT1", "MMS19", "MOB4", "MOCS1", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MRE11", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCEH1", "NCKAP1", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFKB2", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUBP1", "NUBP2", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGFR", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXSM", "PA2G4", "PAAF1", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMS1", "PMVK", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKAG1", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTK7", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RELA", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN3", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPP40", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCCAG3", "SDHA", "SDHB", "SDHD", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SON", "SPAG5", "SPATA5", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TADA3", "TAF6", "TAF6L", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBCB", "TBK1", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TERF2", "TERF2IP", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLE4", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM14C", "TMEM214", "TMEM38B", "TMF1", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TTPAL", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WDR12", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WRAP53", "WTAP", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZNF703", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["AARSD1", "ABCE1", "ADA", "ADSL", "ADSS", "AKT2", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC4", "ANAPC5", "ANKRD17", "AP3M1", "APEX1", "APRT", "ARCN1", "ARFGAP1", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARIH2", "ARL2", "ARMT1", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP6V1D", "ATR", "AURKA", "BABAM2", "BAG6", "BBS9", "BIRC6", "BTF3", "BUB1", "BUB1B", "BUB3", "C12orf43", "CAD", "CAMK1", "CAND1", "CARS", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CCDC124", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CDC25C", "CDC34", "CDC6", "CDCA2", "CDK4", "CDK5", "CDK6", "CHD1L", "CHEK2", "CIAO1", "CKAP5", "CLASP1", "CLINT1", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "COG2", "COG3", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS6", "COPZ1", "CORO7", "CSE1L", "CSK", "CSNK2A2", "CSNK2B", "CTPS1", "CTU2", "CUL2", "CUL3", "CUL4A", "CUL5", "CUL7", "DAXX", "DCAF1", "DCAF7", "DCAF8", "DCTN1", "DCTN3", "DDX1", "DHX29", "DIAPH1", "DICER1", "DIP2B", "DLGAP5", "DNM1L", "DNM2", "DOCK1", "DOCK7", "DUS1L", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLT1", "ECT2", "EEF1A2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHD1", "EIF1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF3A", "EIF3D", "EIF3G", "EIF3L", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELOC", "ELP1", "ELP2", "EML4", "EPRS", "ERCC2", "ERCC6L", "ERGIC2", "ETF1", "EXO1", "EXOC2", "EXOC6", "EYA3", "EZR", "FAM120B", "FARSA", "FARSB", "FBXO7", "FERMT2", "FMR1", "FOXK1", "FRG1", "FXR1", "G6PD", "GADD45GIP1", "GALM", "GBF1", "GCLC", "GCN1", "GEMIN5", "GFPT1", "GGA2", "GMPS", "GOLT1B", "GTF2E1", "GTF2H4", "GYS1", "HAUS6", "HAUS8", "HBS1L", "HECTD1", "HELLS", "HERC5", "HLTF", "HMCES", "HMGB1", "HMGB3", "HPRT1", "HTT", "HUS1", "HUWE1", "IARS", "IDE", "IDH2", "IFT27", "IMPDH1", "INPPL1", "IPO8", "IPO9", "ITPA", "KDELR1", "KIAA0391", "KIF11", "KIF1B", "KIF20B", "KIF2C", "KMT2A", "KNTC1", "KPNA3", "KPNA4", "LARP1", "LARS", "LCMT2", "LIG1", "LLGL1", "LSM14B", "LTN1", "MAP1S", "MAP3K7", "MAPK1", "MAPRE1", "MAPRE2", "MCM3", "MCM4", "MCMBP", "MCTS1", "METTL1", "MGEA5", "MID1", "MMS19", "MOCS1", "MON2", "MOV10", "MPG", "MRRF", "MSH3", "MSH6", "MTAP", "MTBP", "MTIF2", "MYH9", "NAA15", "NAE1", "NAMPT", "NAPA", "NARS", "NARS2", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCAPH2", "NDUFA13", "NEK9", "NFKB2", "NFS1", "NMD3", "NME1", "NME2", "NOSIP", "NPLOC4", "NSUN2", "NUBP2", "NUDCD1", "NUTF2", "OCRL", "ORC3", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "PAFAH1B1", "PAK1", "PANK4", "PARD3", "PAWR", "PCBD1", "PCBP1", "PDCD5", "PDS5A", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGK1", "PGM3", "PHAX", "PHKB", "PIK3C2A", "PIN1", "PKM", "PKN2", "PLAA", "PLCG1", "PLK1", "PMF1", "PMS1", "POLD1", "POLD2", "POLE", "POLR3A", "POLR3B", "POLR3C", "POP1", "PPAT", "PPP6C", "PRKRA", "PRMT5", "PRPS2", "PRPSAP1", "PRPSAP2", "PSMA1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMD14", "PSME3", "PSME4", "PUDP", "PYGL", "QARS", "QKI", "RABGAP1", "RAD54B", "RARS", "RCC2", "REEP3", "REEP4", "RMDN3", "RNF20", "RNF40", "RNGTT", "ROCK2", "RPA3", "RPL10", "RPP40", "RRM1", "RUFY1", "SAMHD1", "SAR1A", "SAR1B", "SCARB1", "SCRN1", "SEC16A", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61G", "SEPT10", "SEPT6", "SET", "SH3PXD2B", "SIRT1", "SIRT2", "SKA3", "SKP2", "SLFN11", "SMARCAD1", "SMC2", "SMC4", "SNX3", "SNX5", "SPC25", "SQSTM1", "SRM", "SRPK1", "SRPK2", "STAMBP", "STAT3", "STMN1", "SUN2", "TARS", "TBCB", "TBK1", "TDP1", "TDRD7", "TFG", "TIMM17B", "TLE4", "TNPO3", "TOPBP1", "TRAPPC11", "TRIM21", "TRIM25", "TRIM33", "TRIP13", "TRMT11", "TRMT1L", "TRMT6", "TROVE2", "TTC4", "TTLL12", "TWF2", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBL7", "UBR1", "UBR4", "UBR5", "UBR7", "UBXN1", "UCHL5", "UFM1", "UFSP2", "UGDH", "UMPS", 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a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d7004e60684c6be3aaaf3bace4cf291040ee2381 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:084b073f9bb2933d5bc1819ec1e080f7d6aff62c4d26b3246a83c6b2d82a240b +size 77376 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3be18c173839d763092a77458cd6bf88654aea62 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Primary microcephaly 6 11 1.968964322488895 0.0489571881998722 2.7402912621359223 10.228155339805824 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"results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e4b4fd9fb97b0e2cb1528f42d713bd2c7d4b0d70 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,35 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary microcephaly 0.6048290333678474 1.968964322488895 0.0489571881998722 0.9971854569988918 0.5958470862819669 11 P42695,Q15058,P47897,Q00534,Q2VPK5,Q15021 6 +Oncogene 0.758532843537908 1.8199464584330325 0.0687671589494338 0.9997602165696504 0.5958470862819669 4 Q96Q89 1 +Cushing syndrome 0.7404685757902173 1.7413963247917323 0.081614131985789 0.9999527994028796 0.6365902294891546 4 P40818 1 +Diabetes mellitus 0.5354687291451327 1.5802829685689566 0.1140420784415683 0.9999992963897004 0.7848778339802055 11 P31751,O60343,O15357,P40763 4 +Diamond-Blackfan anemia 0.5216232284329244 1.5071115243403592 0.1317820733208785 0.9999999339970108 0.8565834765857105 17 P62081,P62847,P08708,P62854,P42766,P39019 6 +Microphthalmia 0.5833069246032345 1.3413549405067722 0.1798052398585619 0.999999999915221 1.0 6 Q6W2J9,O60493 2 +Obesity 0.6107938685140095 1.3168914181118416 0.1878750235252575 0.9999999999733392 1.0 5 Q9BW83,Q3SYG4 2 +Hypotrichosis 0.5281349538018107 1.0776443991671698 0.2811924801818204 1.0 1.0 6 P46778,P48449,Q8IWS0 3 +Hereditary nonpolyposis colorectal cancer 0.7097641086891446 1.0504803531336546 0.2934973192325676 1.0 1.0 3 P54277,P52701 2 +Deafness 0.3284839692091667 1.039440534357215 0.2985999006669741 1.0 1.0 50 Q16740,Q9Y4X0,P18074,P26358 4 +Proto-oncogene 0.3489778989974296 0.9007586042822104 0.3677166816950241 1.0 1.0 44 Q00653,Q01105,Q03164,Q92734,P49915,P26196,O14965,Q9H6U6,Q01844,P31751,P49589,P22681 12 +Systemic lupus erythematosus 0.6555708516191926 0.8465486804113115 0.397246729107326 1.0 1.0 3 P05455 1 +Ciliopathy 0.4054130663102542 0.8320318595633756 0.4053909616130244 1.0 1.0 13 Q3SYG4 1 +Congenital myasthenic syndrome 0.5242346107498912 0.7929234766315563 0.4278224083684505 1.0 1.0 4 Q06210 1 +Lissencephaly 0.4268096512968706 0.7704978592394239 0.4410046244186207 1.0 1.0 8 Q9BSJ2,Q00535,P43034 3 +Bardet-Biedl syndrome 0.8283582089552282 0.6777946060058725 0.4979019315782909 1.0 1.0 2 Q3SYG4 1 +Leukodystrophy 0.3788930357537422 0.6730802439258441 0.5008962418067076 1.0 1.0 20 P49770,O14802,Q13144,P04350,P07814,Q14232,O15160,P61960,P54136,Q9NW08 10 +Glycogen storage disease 0.3490369366064747 0.5584105766740032 0.5765640521284561 1.0 1.0 10 Q93100,P04075,P08237,P36871,P06737,P46976 6 +Hereditary hemolytic anemia 0.3457323655670161 0.5066884809690793 0.6123734141890926 1.0 1.0 16 P11166,P11413,P00813,P04075,P00568,P48506,Q9Y4X0,P00558,P06744 9 +Ectodermal dysplasia 0.3675172572295967 0.4958496548609979 0.6200004886095549 1.0 1.0 8 Q9H4L7 1 +Autism 0.4325657707568047 0.4358269746861428 0.662962271056545 1.0 1.0 4 Q9HCK8,P27635 2 +Leber congenital amaurosis 0.7328358208955252 0.406923919753683 0.684063867174812 1.0 1.0 2 P20839 1 +Albinism 0.7158208955223913 0.3650793471124544 0.7150521771018354 1.0 1.0 2 O00203 1 +Hermansky-Pudlak syndrome 0.7158208955223913 0.3650793471124544 0.7150521771018354 1.0 1.0 2 O00203 1 +Neuropathy 0.2340552462813658 0.2907863362410324 0.7712147361100234 1.0 1.0 51 P50570,P38935,Q5TAQ9,Q92734,Q03001,Q9H0B6,O95163,O00764,Q14203,P26358,Q00796,O60231,Q14204,P54577,Q13614,P48643,O60333 17 +Disease variant 0.1586191592927486 0.2223328093793692 0.8240548129988197 1.0 1.0 862 Q16740,P11310,Q05639,Q70HW3,O43772,Q2M389,Q7Z392,Q7Z6Z7,Q9Y3Z3,Q9BUF5,Q9BXJ9,P54136,Q9NW08,O95394,Q9Y6D5,Q3SYG4,Q14999,P27544,O60333,O60701,Q15392,O60566,P38935,Q9Y6B6,P26196,P26639,P27635,P11802,Q9Y4X0,Q92620,Q8IWS0,P28070,Q9BW83,Q01105,Q9Y263,Q5TAQ9,Q99707,Q08J23,P31751,P24386,Q05086,Q08AM6,O14646,P13639,P13807,Q9H269,P14854,Q96CU9,O75569,Q13535,P46976,P51570,P50570,Q96BN8,P43034,P26640,Q99575,Q93008,Q8TD16,Q15477,P49419,P42356,Q14204,P49770,P34949,P00813,O75880,Q9Y3I1,Q9P2J5,Q9NX46,Q9UID3,Q9P0J0,Q9NPF4,Q9BUR4,Q8NHU6,Q9C0B1,Q9BUK6,Q14232,O76094,P27708,P22314,P22681,O15020,Q99996,Q06210,P26358,P61960,P67870,Q9BTW9,Q08209,P40818,P28340,P21359,Q8N0X7,Q14790,Q13144,Q9BSJ2,Q9Y5L0,Q13432,P08397,Q01433,P07741,A1X283,Q00796,P57081,Q9BV10,Q92734,Q6W2J9,Q07864,P42858,Q00534,P11172,Q8NCE2,Q92990,Q15813,P18074,O60826,Q06787,Q96F86,Q14353,Q93100,Q9NR45,O00429,P62854,O43318,P08243,O60231,P31939,P40763,Q4J6C6,Q6IA86,Q7LBC6,Q15126,Q2TAL8,P00374,P48449,Q06124,Q13057,Q96C86,Q9GZT9,Q13501,O95630,P42695,Q96C23,Q96IJ6,Q00653,P11413,O14802,P08237,P00492,P36507,P48735,Q96D71,Q8IWV7,Q96AY3,Q9NSD9,O15357,Q15645,P10589,O95163,P04350,P07437,P20839,P50851,P52701,Q9BY32,Q9H2U2,Q9NUQ7,Q9NUW8,Q9UHD2,Q14746,Q15058,Q14738,P49589,P06737,P30566,P53602,Q13614 178 +Non-syndromic deafness 0.2582421685589753 0.1798105434655807 0.8573013060423214 1.0 1.0 15 P35579,Q9Y4A5,P49736,Q96I59,O60610,Q969T9,P35241 7 +Joubert syndrome 0.6125373134328417 0.1656776106389891 0.8684106666461662 1.0 1.0 2 O43924 1 +Cancer-related genes 0.2018073902997669 0.1130372696143169 0.910001007676972 1.0 1.0 393 Q03164,P55210,P25205,Q7Z6Z7,O00299,O75874,O60566,P09972,P14618,P26196,P27635,P49427,P11802,Q96AE4,Q15382,Q8IWS0,Q15648,Q13617,Q99661,Q01105,P80303,P31751,P55212,P55060,O75534,P04183,P13639,Q14240,Q13535,P50570,Q01844,P67809,O95067,Q9UER7,P22681,Q99996,P07099,P67870,P40818,P28340,P21359,Q14790,P43490,Q9Y2L1,Q9HC35,Q92734,Q6W2J9,P15531,Q07864,Q00534,Q9Y620,P41440,P18074,Q14258,Q5VU43,Q9NR09,P16949,P31939,P40763,P19784,Q9H6R7,P00374,P20248,P49327,Q06124,P14635,P27695,P31946,Q13309,Q00653,P11413,O00221,P09960,P19174,P36507,P48735,P53396,Q96PU8,O15357,O14965,O95071,P63241,P30307,P52701,P28482,Q9H2U2,P49589,P12277,P42574 89 +Amyotrophic lateral sclerosis 0.2170842177169603 0.1005781564618946 0.919885337379208 1.0 1.0 15 Q9NRR5,Q9UHD2,Q14203,Q13501,P07737 5 +Kallmann syndrome 0.3693639892505245 0.0984250383501666 0.9215947934765318 1.0 1.0 3 Q9BZH6,Q9P2D1 2 +FDA approved drug targets 0.2021037118855408 0.0635332365821924 0.9493418937293864 1.0 1.0 130 P00813,P20645,O75116,P78559,P20618,Q14353,P23921,Q00653,O75874,P00492,P36507,P11802,P48735,P53396,P26358,P31939,P49721,Q99707,P07437,P00374,P20839,P49327,P13639,P14735,P28482,P36404,Q07864,Q00534,P28074,P12277,O60664,P42574 32 +Mental retardation 0.1812933688258849 0.0629200613666786 0.9498301598347398 1.0 1.0 175 Q05639,Q2M389,Q9UID3,Q9NPF4,Q7Z6Z7,Q15813,Q9BXJ9,O60826,Q92796,Q96IJ6,Q06787,Q96F86,Q3SYG4,Q9NR45,P26196,P27635,P36507,Q9Y4X0,P41252,P08243,P67870,Q8IWS0,Q92974,Q08209,Q9NSD9,Q01105,Q6IA86,Q7LBC6,Q9Y263,Q9Y4P8,Q2TAL8,Q08J23,Q9BSJ2,O14646,P48449,P57081,Q13535,Q96C86,P26640,P42858,Q14738,Q93008,Q14204 43 +Aicardi-Goutieres syndrome 0.2501677652721932 0.0595344994967674 0.9525263875736536 1.0 1.0 4 Q9Y3Z3 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c17879e04fd5456e0e42836dd796a777244e4900 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Atrial septal defect", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital erythrocytosis", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABHD12", "ABHD5", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "AMMECR1", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APRT", "ARCN1", "ARFGEF2", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARSA", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATR", "ATXN10", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS9", "BCAP31", "BCAS3", "BCAT2", "BCKDHB", "BCL10", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "CA8", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT5", "CD320", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC42", "CDC6", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDKAL1", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHM", "CHMP2B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COG2", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "CORO1A", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCAF8", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "ECT2", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGLN1", "EHHADH", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "EPB41", "EPB41L3", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC2", "ERCC3", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC6B", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP1A", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FUBP1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATA6", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GCLM", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GINS1", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNB1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GPT2", "GRB2", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GUF1", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD11", "HPRT1", "HSD17B10", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2R", "IGHMBP2", "IKBKG", "ILF3", "ILK", "IMPDH1", "IMPDH2", "INF2", "INPPL1", "INTS1", "INTS8", "IPO7", "IQSEC1", "IRF2BPL", "IRS4", "ISCA2", "ITGB1", "ITPA", "ITPR2", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LIG4", "LIMD1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MALT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MASTL", "MATR3", "MBD1", "MBNL1", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED23", "MESD", "MFN2", "MGA", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYO6", "NAA15", "NAGLU", "NAMPT", "NANS", "NARS2", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCSTN", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEK9", "NF1", "NFKB2", "NFKBIE", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F1", "NSD1", "NSD2", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAK1", "PANX1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDCD4", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDSS2", "PDXK", "PEPD", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN13", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAD21", "RAD23B", "RAD54B", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBM10", "RBM12", "RBM15", "RBM28", "RBMX", "RBPJ", "RCC1L", "RDH11", "RDX", "REEP6", "RELA", "REPS1", "RFC1", "RFC2", "RFK", "RHEB", "RHOA", "RHOC", "RINT1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "ROCK1", "ROCK2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", 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pval_100 pval_250 pval_500 +Methyltransferase 21 49 3.331414635148368 0.0008640579648127 10.03640776699029 44.03155339805825 0.2422885074421102 0.6109536454251433 5.627699758479494 7.824003054737818 0.8671459134529956 0.3232405124765111 0.1533790256375115 0.0138651836978069 0.0010249737746858 0.002678381138764 +Serine/threonine-protein kinase 40 72 3.149243097997337 0.001636939631465 18.424757281553397 58.6747572815534 -0.2386691929507323 0.5877823066168736 8.485376838226976 12.595500957030788 0.9438037227041202 0.3256457489861977 0.7394672475646835 0.2850934111042308 0.6924407898062603 0.6424985904497897 +Protease 31 89 2.4248724607134826 0.0153137656081892 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.0210954419571948 0.0003051086447068 0.0004326275057873 2.128766697217048e-06 +Serine protease 2 9 2.293754700877065 0.0218045927577883 2.325242718446602 9.143203883495143 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b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 98, + "title": "Average number of proteins per term", + "value": 40.90816326530612 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c700810b985898829fa2ecd68b0cc71b601c8d2d --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8a034e89a747d894282fb6c21a397c8187a1a3a4 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,55 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Methyltransferase 0.5789271813080289 3.331414635148368 0.0008640579648127 0.0812252452300829 0.0802100419417875 49 Q03164,Q9BV86,Q9BV44,Q7L2J0,Q7Z2T5,Q14353,O60725,P26358,Q86TU7,Q99873,Q99707,O60294,Q08J23,O60678,Q7Z4G4,Q8TEA1,Q8N1G2,Q9UBP6,Q9H993,O14744,Q86W50 21 +Serine/threonine-protein kinase 0.4741255911709491 3.149243097997337 0.001636939631465 0.1483260612012093 0.0802100419417875 72 P49761,Q00535,P33981,P53350,Q8TD19,P52564,Q16539,Q99570,Q96KB5,O75116,Q13546,Q16512,O96017,O15111,O60566,P36507,P11802,O43318,Q96SB4,P19784,P78362,O43683,Q13555,Q13464,Q13043,O14965,Q9Y4B6,P31751,P28482,Q16513,Q14012,Q13535,Q13153,P45985,Q99986,Q9NYV4,Q9UHD2,Q9H2G2,Q00534,P17612 40 +Protease 0.4334773567382907 2.4248724607134826 0.0153137656081892 0.7796104832332557 0.3027101807902081 89 Q16740,P55210,Q96K76,P17655,Q9Y4P1,P51784,P48147,P09960,Q9NY33,Q96FW1,Q96RU2,Q9H4A4,P40818,Q4J6C6,O43847,Q9UPT9,Q14790,Q86TI2,P55212,P55786,Q86UV5,Q92905,Q96BN8,Q9NUQ7,P42574,P28074,P52888,Q96FZ2,O95630,P50579,Q01804 31 +Serine protease 0.6963442582836573 2.293754700877065 0.0218045927577883 0.8847314836933354 0.3027101807902081 9 P48147,Q16740 2 +Thiol protease 0.5784441888488 2.2458903028825543 0.0247110351665476 0.913887854537639 0.3027101807902081 34 P55210,Q96K76,P17655,Q14694,Q9Y4P1,P51784,P45974,Q96FW1,Q96RU2,P40818,Q9UPT9,Q14790,Q6GQQ9,P55212,Q86UV5,O94966,Q96BN8,Q9NUQ7,Q93008,P42574,Q01804 21 +Initiation factor 0.5444459835690607 2.19001118058786 0.0285234259732423 0.9413364159250758 0.3052134300174218 38 P49770,Q15056,Q14232,Q9ULC4,P41567,Q14152,Q7Z478,O60841,P46199,O43432,O15371,P78344,Q9BY44,Q13144,Q9Y262,P41214,Q04637,Q14240,P05198,Q9NR50,P06730,O60573,O75821 23 +DNA-directed DNA polymerase 0.8308471831464386 2.129305417875086 0.0332289998505492 0.9635485987594568 0.3052134300174218 4 P28340 1 +Actin capping 0.660780259881901 1.832664159537214 0.0668525303600984 0.9988646553718078 0.4717921357316468 7 O15020,P47756,P47755 3 +tRNA-binding 0.5643755647560804 1.7783582585748683 0.0753450336398029 0.9995365410762306 0.4717921357316468 19 P38935,Q7Z4G4,Q9HAV4,Q7Z2T5,Q7Z7L1 5 +Cyclin 0.743803033158579 1.7559300108686042 0.0791003598856421 0.999688967537797 0.4717921357316468 4 P20248,O95067 2 +Aminopeptidase 0.5341006015029898 1.5707032889179484 0.1162515848975926 0.9999945019650136 0.5996134378928465 12 Q9NY33,Q86TI2,P55786,P50579,Q9H4A4 5 +Kinase 0.3944782657270482 1.5353495195299625 0.1246979964309051 0.9999978547574032 0.6071593522019089 120 P49761,Q00535,P33981,P53350,P41240,Q8TD19,P52564,Q16539,Q99570,Q96KB5,P22392,O75116,Q16512,O96017,O15111,Q13572,O60566,P08237,P14618,P36507,P11802,P17858,O43318,P11908,Q969G6,Q96SB4,O00443,P49903,P19784,P78362,O43683,Q13555,Q15126,Q13464,Q13043,O14965,Q9Y4B6,P31751,Q8TBX8,P04183,Q13057,P28482,P17612,Q16513,Q14012,Q13535,Q9UJ70,P51570,P45985,Q9BZX2,Q13153,Q99986,Q9NYV4,P15531,P00568,P35790,Q9UHD2,O00764,Q9H2G2,Q00534,P12277,P30085,Q01813,P42356,P00558 65 +Guanine-nucleotide releasing factor 0.4961219550045462 1.390725222982896 0.1643087659640456 0.9999999770653047 0.7000982201946292 22 Q96N67,Q92538,Q9P258,P80303,Q9H8V3,Q14185,Q14155,Q9NPQ8,Q14C86,Q9Y6D5 10 +Allosteric enzyme 0.4773583967806223 1.2835855781339882 0.1992869985501468 0.9999999996526764 0.7040191628227903 23 O60701,Q06203,P08237,P14618,Q9Y3Z3,P17858,P06737,P27708,Q01813,P13807,P14735,P23921 12 +Cytokine 0.6257364353342258 1.2350130711535998 0.2168256394842946 0.9999999999603604 0.7040191628227903 4 P43490,P06744 2 +Metalloprotease 0.4633258539573818 1.2330048564085765 0.2175739523002362 0.9999999999639052 0.7040191628227903 26 O43847,Q92905,P09960,Q9NY33,O95630,P55786,P52888,P14735,Q9H4A4,O00487 10 +Protease inhibitor 0.5578225072303331 1.2193801530115462 0.2226999392602704 0.9999999999810464 0.7040191628227903 6 P30086 1 +Tyrosine-protein kinase 0.4457047228891029 1.0685663535624703 0.2852651164480799 0.9999999999999948 0.8021795184077869 11 P49761,P45985,P33981,P36507,P41240,P52564,Q02750 7 +Serine esterase 0.5084287949931411 0.984234359211744 0.3250002955490729 1.0 0.8847230267724763 6 Q86TX2,O00154 2 +Tumor antigen 0.5559177486211734 0.9282306400631029 0.3532879438893404 1.0 0.916777361721929 4 Q96RS6,Q9UNF1 2 +Helicase 0.303553479490242 0.9035344229702006 0.3662423273703625 1.0 0.916777361721929 89 P25205,P18074,Q9H6S0,O14981,Q7Z478,Q9H4L7,P38935,Q6P158,P26196,P42694,P46063,Q92499,Q92620,O60231,Q9NUL7,Q8IX18,O14646,Q14240,Q7L014,Q7Z7L1,Q86WJ1,Q9Y620,Q15477,Q14527 24 +Elongation factor 0.4047721852423014 0.840267710614528 0.4007583013709095 1.0 0.916777361721929 11 Q05639,Q9Y450,P63241,P13639,P26641 5 +Aminoacyl-tRNA synthetase 0.3886195874273134 0.8392768601152681 0.4013139652370585 1.0 0.916777361721929 32 Q9P2J5,Q96I59,P26639,O43776,P26640,P49591,P07814,P41250,P47897,P49589,P41252,P23381,P54136,P54577,Q9Y285,Q9NSD9 16 +Endonuclease 0.4083825758654341 0.837592770295962 0.4022594546330913 1.0 0.916777361721929 17 Q9Y2L1,Q13283,P39748,O94919,Q9UPY3,Q9UQ84,P27695 7 +Decarboxylase 0.4205433153901312 0.6587108564725749 0.5100814601437011 1.0 1.0 7 Q6P996,P11172,P06132 3 +Dioxygenase 0.36339802885209 0.5903372717603329 0.5549645561154071 1.0 1.0 21 Q7LBC6,Q9GZT9,Q6P6C2,Q9C0B1,O00625,Q32P28,P13674 7 +Thiol protease inhibitor 0.4742496353810776 0.589828817516981 0.5553054205577337 1.0 1.0 4 Q9NR09 1 +Threonine protease 0.5825619587936817 0.588033375281971 0.5565098910002371 1.0 1.0 3 P28072,P28074 2 +Nucleotidyltransferase 0.3585454539645452 0.5774338927022572 0.5636463841370511 1.0 1.0 25 P28340,O14802,Q9BWH6,Q07864,Q5TAX3,O60942,Q13057,P49642 8 +Nuclease 0.3290373985180861 0.5455386268337917 0.5853831217509842 1.0 1.0 37 P28340,Q9Y2L1,Q9HB07,Q9NUW8,Q92499,O15091,Q9UIV1,Q13283,O75792,P39748,O94919,Q9UPY3,Q9UQ84,P27695 14 +Growth factor 0.435214382052257 0.5409155277740567 0.5885658076518507 1.0 1.0 5 P60983,P51858 2 +GTPase activation 0.3435766510338582 0.4974828844946617 0.6188485695525945 1.0 1.0 25 P21359,Q8N6T3,O60343,P43487,Q14C86,Q86X10,Q9NVG8,Q9Y3P9,P24386,Q9BTW9,Q8TC07,Q15042 12 +Motor protein 0.3263803077810472 0.468691771421705 0.6392899694634462 1.0 1.0 33 P35579,P50570,O60333,Q9H0B6,Q15058,Q14204,Q92614,P33176,Q96Q89,P63172,O43237,P52732,Q9Y6G9 13 +Multifunctional enzyme 0.3180870382685293 0.3970407695050632 0.6913373965469454 1.0 1.0 30 P11172,O60942,P49327,P31939,Q14527 5 +Exonuclease 0.3242139087393458 0.3967799532981833 0.6915297348272902 1.0 1.0 22 Q9Y2L1,P28340,Q9NUW8,Q92499,P39748,Q9UQ84,P27695 7 +Ligase 0.2155093546313912 0.2366466132732207 0.8129309549529378 1.0 1.0 76 Q9P2J5,Q14258,P27708,P54136,P22314,O00442,P30520,P49915,P26639,P07814,P48506,P47897,P08243,P41252,P54577,P18858,Q9NSD9,Q96I59,O43776,P26640,A0AVT1,P17812,P49589,O15067,Q9Y285 25 +Voltage-gated channel 0.3627252307666582 0.2268086685173879 0.8205725228510381 1.0 1.0 4 O00299 1 +Chloride channel 0.333796041607697 0.2088984358256222 0.8345275252548923 1.0 1.0 5 O00299 1 +Protein phosphatase 0.2705983258830386 0.1959970232954949 0.8446124958790568 1.0 1.0 22 O00743,P60510,Q99504,Q99956,O60942,P30307,Q9UNI6,P51452,Q06124,O15355,P24666,Q08209 12 +Prenyltransferase 0.6188059701492596 0.1749027802313977 0.8611560256415909 1.0 1.0 2 Q92696 1 +rRNA-binding 0.2553948140943934 0.1591761004556254 0.8735301328507743 1.0 1.0 20 Q9NUL7,P62917,P62701,P62269,Q7L8L6 5 +Glycosyltransferase 0.2304013501827974 0.1193771768746402 0.90497654219535 1.0 1.0 38 P26572,P00491,P11172,Q06203,Q9BV10,P00492,Q13126,P07741,P06737,P13807,P43490,O43505 12 +Transferase 0.3106094002489699 0.1161130778949976 0.9075629242611232 1.0 1.0 405 Q03164,Q9BV86,Q00535,Q7Z6Z7,Q99570,O75116,Q9NW08,P27544,O60725,O60566,P14618,P49427,P11802,Q13126,O60942,Q86TU7,Q96SB4,P78362,Q9C0C9,Q9HCL2,Q9UKG9,Q9BWH6,Q99707,Q9Y4B6,Q08J23,P31751,P61086,Q05086,O60678,Q7Z4G4,O95376,P04183,P13807,Q13535,Q8N1G2,P46976,P26572,P51570,Q9BZX2,P45985,Q96P11,O94822,P42356,Q86W50,Q14527,Q9NPF4,Q9C0B1,Q5TAX3,P27708,P22392,Q7L2J0,Q7Z2T5,Q16512,O96017,O43505,P22681,O15111,Q13572,Q9Y314,Q06210,P26358,Q15386,P49903,P28340,P08397,P07741,P43490,Q9UBP6,Q9BV10,P15531,P35790,Q07864,Q00534,Q96JP5,Q16763,P49761,P11172,Q9NT62,Q14258,P78417,Q14353,Q9NR09,Q9NR45,Q9UBT2,P68036,P17858,O14929,O43318,P19474,P31939,P49642,P19784,Q96EB6,Q15126,P49327,Q13057,Q7Z7E8,Q99986,Q9BQC3,Q9UKK9,Q5VTR2,P41240,Q9BV44,O14802,P08237,P00492,P36507,P53396,Q8IWV7,Q99873,Q9NRN7,Q9UII4,Q9ULT8,O14965,O60294,O95071,P51003,P28482,Q8TEA1,Q9H993,Q9BWD1,Q9UHD2,O14744,P06737,P12277,P28161 126 +Hydrolase 0.2665842721748568 0.1148925688791986 0.9085302752649068 1.0 1.0 401 Q16740,Q08623,P55210,P17655,P25205,O60502,Q9H6V9,Q9NPH0,Q9Y3Z3,O15091,Q9UNI6,Q9Y4P1,P51784,Q9UQ84,O00487,O14981,P48147,Q9H4L7,P38935,Q2TAA2,P26196,P33316,P46063,Q92499,O60942,Q92620,Q96RU2,Q9UPT9,Q9HB07,Q8IX18,Q9Y570,Q86TI2,P55212,P55786,O14646,P14735,Q14240,P50570,Q96BN8,Q99575,Q93008,Q9NVE7,P52888,Q15477,Q8N3C0,Q14527,Q01804,P00813,Q9Y295,Q9NX46,Q9NQW7,Q99956,Q13572,Q9NTK5,Q6P158,Q99504,P07099,O75818,Q5TFE4,Q08209,P40818,P28340,O43847,O00154,Q14790,Q01433,O94919,Q7Z7L1,Q9Y2L1,Q07864,Q9Y620,Q96FZ2,Q96K76,Q8NCE2,P18074,Q7Z478,Q96PE3,Q9BSD7,Q9NY33,O00429,O60231,P29372,P31939,Q4J6C6,P49327,Q06124,Q7L014,Q86UV5,Q86WJ1,Q92905,Q96C86,Q9UKK9,P28074,O95630,P18669,P27695,Q6PL18,Q86TX2,Q9H6S0,O60841,P09960,P19174,P42694,Q96IU4,Q96FW1,Q9H4A4,Q9NUL7,O15357,P30307,Q9H993,Q9BY32,Q9H2U2,Q9NUQ7,Q9NUW8,P42574,P50579,Q13614 117 +Developmental protein 0.1983400143409642 0.1118929456404895 0.9109082900418122 1.0 1.0 87 Q96EB6,Q9Y263,Q96N67,Q9Y314,Q96C57,Q99504,Q14997,P31751,P85037,O94967,P16949 11 +Activator 0.2158956087145941 0.098318377994034 0.9216794853535868 1.0 1.0 113 P53999,Q6PL18,P85037,Q6P1K2,Q06787,Q3B7T1,Q00653,P38935,Q99504,P26358,Q96EK7,P40763,Q9UPT9,P10589,Q92616,Q8NE71,Q9Y2X0,P67809,Q14527,P27695 20 +Heparin-binding 0.2554270383489068 0.0951120297234608 0.9242258430578398 1.0 1.0 6 P51858 1 +DNA-binding 0.1898642154538597 0.0786597598932047 0.937303253215779 1.0 1.0 244 P53999,Q03164,P54277,Q9NUD5,P25205,Q7Z6Z7,Q9BQ70,P85037,P18074,Q92547,Q9UQ84,Q9Y237,O14981,Q00653,Q9H4L7,Q9BUI4,P38935,P46063,Q92499,P26358,Q96AE4,P09429,Q8IWS0,P19474,Q15648,P40763,P28340,Q01105,Q9UBD5,Q66K74,Q9BWH6,P80303,P10589,P20839,P20585,P52701,P28482,Q13535,P35269,Q07864,Q9Y620,Q96FZ2,P67809,Q14527,P27695 45 +Phospholipase A2 inhibitor 0.5137313432835908 0.0677004958827725 0.9460240545615052 1.0 1.0 2 P12429 1 +Signal transduction inhibitor 0.2547789725208995 0.0625358940854022 0.9501360785186216 1.0 1.0 4 P49840,P49841,P49407 3 +Chaperone 0.1814602509159582 0.0595767113753187 0.9524927670442044 1.0 1.0 103 O75880,P61221,Q9BUR4,Q15813,Q9UER7,Q99615,P78318,Q9H3U1,P46379,O75937,O75165,P08238,O75832,Q9BTW9,O43765,O75347,P31689,Q8WXX5,P49368,Q01105,Q99426,P50991,Q9UL15,P40227,Q99471,Q99733,P17987,O75607,Q16543,Q8TAT6,Q99832,P07900,O95456,Q15785,Q92688,O60884,O95433,Q969U7,Q0VDF9,P20290,P48643,Q9BTT0 42 +Calmodulin-binding 0.1719023444852318 0.0517130209579521 0.9587573618988484 1.0 1.0 33 Q93100,Q5T4S7,P35579,Q13555,O43815,Q99439,P35611,Q01844,P46940,P32929,Q9UEY8,Q9UM54,Q08209,Q14012 14 +Ribosomal protein 0.1469593192359138 0.0495708050619022 0.960464412204705 1.0 1.0 116 P46776,P84098,P62750,P60866,P62917,P62906,P61254,P61247,P50914,P46778,P62081,P32969,P62701,P27635,P62847,P08708,P62854,Q7Z7F7,P42766,P39019,P62269,P61513,P47914,P83731,Q8TAE8,P05387,P62753,P18621,P62899,P15880,Q9HD33,P39023,P62266,P46783,P62841 35 +Actin-binding 0.1420477370494137 0.0444422887292148 0.9645518533998034 1.0 1.0 82 P47756,Q14331,Q6IBS0,P47755,P57737,O15020,O00401,P35611,P35241,Q86TU7,P60981,P35579,O15357,Q99439,Q9UEY8,Q03001,O60610,P35080,Q9Y613 19 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6132711a258385bc41efc62879ede9fa8ebf7867 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligand-gated ion channel", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APEH", "APEX1", "APRT", "AQR", "ARFGAP1", "ARFGEF2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATE1", "ATG3", "ATG4B", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BANF1", "BAZ1B", "BAZ2A", "BCAT2", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BPHL", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CAD", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CERS1", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHM", "CHML", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CROT", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CSTF2T", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTSA", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGLN1", "EHHADH", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "F11R", "FADS2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "INTS11", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "IVD", "KARS", "KAT7", "KATNA1", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KRR1", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD3", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MALT1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MATR3", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NARS2", "NAT10", "NAXE", "NCEH1", "NCL", "NCOA5", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NF1", "NFKB2", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2F1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM7", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD54B", "RAI1", "RALA", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RFK", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPP40", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSBN1L", "RSF1", "RTCA", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBF1", "SC5D", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD5", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SOD2", "SON", "SORD", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE4", "TMEM126B", "TMEM38B", "TMF1", "TMOD3", "TMTC3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TSTA3", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBP1", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "WARS", "WASF2", "WASL", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR47", "WDR5", "WNK1", "WRAP53", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "ZADH2", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFP91", "ZFR", "ZMPSTE24", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZNF703", "ZZZ3"], "leading_proteins": ["AASDHPPT", "ABCE1", "ABCF1", "ABHD14B", "ACAT2", "ACLY", "ACOT1", "ACOT7", "ACP1", "ACP6", "ADA", "ADD1", "ADD3", "ADPRHL2", "ADSS", "AHSA1", "AK1", "AKT2", "ALG12", "ALKBH5", "AMPD2", "ANP32B", "ANP32E", "ANXA3", "APEX1", "APRT", "ARFGAP1", "ARFGEF2", "ARHGEF7", "ARIH2", "ARMT1", "ARRB1", "ASCC3", "ASNS", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATR", "AURKA", "B4GAT1", "BAG5", "BAG6", "BIRC6", "BTAF1", "BTF3", "BUB1", "BUB1B", "C12orf43", "CAD", "CAMK1", "CAMK2G", "CAPN2", "CAPZA2", "CAPZB", "CARS", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CCNA2", "CCNB2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CDC25C", "CDC34", "CDC37", "CDK12", "CDK4", "CDK5", "CDK6", "CERS1", "CHD1", "CHD1L", "CHEK2", "CHKA", "CHM", "CHUK", "CKB", "CLIC1", "CLK3", "CLPP", "CMPK1", "CMTR1", "CNN2", "CNOT7", "COASY", "COPS5", "CORO7", "CROT", "CSK", "CSNK2A2", "CTH", "CTPS1", "DAXX", "DCAF1", "DCPS", "DDX1", "DDX28", "DDX46", "DDX6", "DHX16", "DHX29", "DHX38", "DHX40", "DHX57", "DIAPH1", "DICER1", "DIS3", "DNAJA1", "DNAJA2", "DNAJC13", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DPH2", "DPP3", "DPP9", "DRG1", "DST", "DSTN", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLT1", "ECT2", "EDRF1", "EEF1A2", "EEF1G", "EEF2", "EGLN1", "EIF1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF3A", "EIF3D", "EIF3G", "EIF3L", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF5B", "ENDOD1", "EPHX1", "EPRS", "ERCC2", "EWSR1", "EXO1", "EYA3", "FAM120B", "FARSA", "FARSB", "FASN", "FASTKD5", "FEN1", "FHOD1", "FMR1", "FOXK1", "FRG1", "FTO", "FUBP1", "G3BP1", "GADD45GIP1", "GALK1", "GAMT", "GAPVD1", "GARS", "GBF1", "GCLC", "GCN1", "GFPT1", "GMFB", "GMPS", "GPAM", "GPI", "GSK3A", "GSK3B", "GSTM2", "GSTO1", "GTF2F1", "GYG1", "GYS1", "HAT1", "HBS1L", "HDGF", "HECTD1", "HELZ", "HERC5", "HLTF", "HMBS", "HMCES", "HMGB1", "HPRT1", "HSP90AA1", "HSP90AB1", "HSPA14", "HUWE1", "IAH1", "IARS", "ICMT", "IDE", "IGBP1", "IGHMBP2", "IMPDH1", "INPP4A", "INPPL1", "IQGAP1", "ITPA", "ITPK1", "KDM3B", "KIAA0391", "KIF11", "KIF14", "KIF1B", "KIF20B", "KIF5B", "KLC2", "KMT2A", "LARS", "LCMT2", "LDAH", "LIG1", "LTA4H", "LTN1", "MAGED2", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MCM3", "MCTS1", "MED1", "MED16", "MEPCE", "METAP2", "METTL1", "METTL16", "MGAT1", "MGEA5", "MPG", "MRPL47", "MRPL55", "MSH3", "MSH6", "MTAP", "MTIF2", "MTMR14", "MTMR2", "MTR", "MYG1", "MYH9", "MYO18A", "MYO6", "NAGK", "NAMPT", "NANS", "NAP1L4", "NARS", "NARS2", "NEK9", "NF1", "NFKB2", "NME1", "NME2", "NOSIP", "NPEPPS", "NPLOC4", "NPM3", "NR2F1", "NRDC", "NSUN2", "NSUN5", "NSUN6", "NT5DC1", "NTMT1", "NTPCR", "NUCB2", "NUDCD1", "NUDT5", "OLA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "P3H1", "P4HA1", "PAK1", "PANK4", "PAPOLA", "PBK", "PDXDC1", "PDXK", "PEBP1", "PFAS", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN2", "PGAM1", "PGK1", "PHF6", "PHKB", "PI4KA", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLK1", "PMF1", "PMS1", "PMVK", "PNP", "POLD1", "POLE", "POLR3A", "POLR3B", "POLR3C", "POP1", "PPA2", "PPAT", "PPM1G", "PPME1", "PPP3CA", "PPP4C", "PPP6C", "PREP", "PREPL", "PRIM1", "PRKACA", "PRMT1", "PRMT3", "PRMT5", "PRPS2", "PSMB5", "PSMB6", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PTPN11", "PUDP", "PYGL", "QARS", "RAB3GAP1", "RABGAP1", "RABGGTA", "RAD54B", "RALGAPB", "RANBP1", "RARS", "RCC2", "RDX", "RECQL", "RFK", "RIC8A", "RIPK1", "RNASEH2A", "RNF20", "RNGTT", "RNPEP", "ROCK1", "ROCK2", "RPAP1", "RPL10", "RPL10A", "RPL14", "RPL17", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27A", "RPL29", "RPL3", "RPL31", "RPL35", "RPL37A", "RPL8", "RPL9", "RPLP2", "RPP40", "RPS10", "RPS15", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS26", "RPS3A", "RPS4X", "RPS6", "RPS7", "RRM1", "RTCA", "SAMHD1", "SARS", "SCO1", "SEPHS1", "SET", "SETD3", "SGTA", "SIRT1", "SKIV2L", "SLFN11", "SLK", "SMARCAD1", "SPTBN2", "SRPK1", "SRPK2", "STAMBP", "STAT3", "STK4", "STMN1", "STRN", "SUB1", "TARS", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCF25", "TCP1", "TDP1", "THOP1", "THUMPD3", "TK1", "TOMM34", "TOPBP1", "TRIM21", "TRIM25", "TRMT11", "TRMT1L", "TTK", "TWF2", "UBA1", "UBA2", "UBA6", "UBE2K", "UBE2L3", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBR1", "UBR4", "UBR5", "UCK2", "UFSP2", "UGDH", "UMPS", "UNC45A", "UROD", "USP10", "USP11", "USP19", "USP22", "USP28", "USP47", "USP48", "USP5", 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sha256:38847786101dffc3a11a44a1092ae26444220611c0637fbc4b368f5314be0a0a +size 167371 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d522927b225f7776a6349f24c7cb3093f72a58be --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2dfa53a35235fc81aef437b75a440913c9a127af6ca67f3e9a86fa97274b3fdc +size 91733 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..516fabb9a3112f0d097df1d8fc3f60486232fd9c --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Predicted intracellular proteins 1222 3115 8.292361075813595 1.1102230246251563e-16 1052.9126213592233 2930.233009708738 -5.248196350890207 0.108353777008802 367.4824441165934 294.4528727150831 7.24167812525605 0.3049463326237019 0.2762410355989638 0.125779372443833 0.0017927572847679 5.6337374183262725e-09 +Enzymes 275 989 3.491277125149308 0.0004807173517105 180.46601941747576 916.0339805825242 -0.3890709639022823 0.4315149002113257 67.0110577071333 90.66568168613344 1.858068218066602 0.4271937700203886 0.0226241817735342 0.0049735784438675 2.4741036214258743e-05 6.216668634636746e-13 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b677505811056a622194d467594ee15405f16cd6 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3352, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 509.7142857142857 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..41f9845e5923f30700d0dcb9cef4a56bfa09490d --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C097/C097_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4a3b013915d900d18a9929d51c1225adae988097 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Enzymes 0.2547609903860684 3.491277125149308 0.0004807173517105 0.0100466830884654 0.0050475321929604 989 Q16740,P11310,Q03164,Q9BV86,Q08623,P55210,Q8N4Q0,Q00535,P17655,P25205,Q7Z6Z7,O60502,Q9NPH0,Q99570,O15091,Q9UNI6,Q9Y4P1,P51784,O75116,P25787,P54136,Q9NW08,O95394,O00487,P48147,O60701,Q9H4L7,Q15392,O60725,O75874,P38935,O60566,P09972,P14618,P26196,P26639,P28066,P49427,P33316,Q13126,P11802,P46063,Q92499,O60942,Q96BP3,Q92620,Q96RU2,Q86TU7,Q96SB4,P28070,P18858,P78362,Q9C0C9,Q9UPT9,Q9HCL2,Q9UKG9,Q99707,Q8IX18,Q9Y4B6,P31751,Q86TI2,Q9Y570,P55212,P55786,Q05086,Q08J23,P61086,O14646,O95376,P04183,P13807,P14735,Q14240,Q13535,Q8N1G2,P46976,Q9BYN0,P26572,P51570,P50570,Q9BZX2,Q96BN8,Q8N8N7,P45985,Q6P6C2,P30519,P26640,Q99575,P17812,O94822,Q93008,Q32P28,P52888,Q8N3C0,P49419,P42356,Q86W50,Q14527,Q01804,Q9Y285,P34949,P00813,Q9P2J5,Q9NX46,Q9NQW7,Q9NQR4,Q9NPF4,Q99956,Q9C0B1,Q5TAX3,P27708,P25786,P22392,P22314,P20618,Q16512,O96017,P31350,P23921,P22681,O15111,Q13572,Q9UHG3,O00743,O00442,Q06203,Q6P158,P30520,Q9Y314,P04075,P49915,Q99504,P61081,Q06210,P07099,O75818,P26358,P30046,O00625,P48506,P47897,P45974,P41252,Q8IYS1,Q969T7,Q969G6,Q08209,Q15386,P49903,P40818,P28340,Q8N806,O43847,Q2NKX8,O00154,Q14790,Q15257,P08397,Q01433,P07741,Q00796,P43490,Q9UBP6,Q9BV10,P15531,P35790,Q07864,Q00534,Q96JP5,O15067,Q16763,P49761,P11172,Q96K76,P18074,Q14258,P78417,Q14353,Q7Z478,Q96PE3,Q9BSD7,Q9NR09,Q9NR45,Q9NY33,P68036,O00429,P17858,O14929,O43318,P08243,O60231,P19474,P29372,P31939,P49721,P19784,Q96EB6,Q4J6C6,Q7LBC6,Q15126,P00374,P48449,P49327,Q06124,Q13057,Q7L014,Q7Z7E8,Q86UV5,Q86WJ1,Q8WUX2,Q92905,Q96C86,Q99986,Q9BQC3,Q9GZT9,Q9UKK9,Q5VTR2,P28074,O95630,P13674,P18669,P60900,P53004,P41240,Q96C23,Q86TX2,Q8WUA2,Q9H6S0,Q9Y237,P11413,O14802,O60841,P08237,P09960,P00492,P19174,P36507,P48735,P49720,P53396,Q96FW1,Q8IWV7,Q96AY3,Q99873,Q9H4A4,Q9NRN7,Q9NSD9,Q9NUL7,Q9P2T1,Q9ULT8,O15357,O14965,O43776,O60294,O95071,P20839,P30307,P51003,P28482,Q7L5N1,Q9BWD1,Q9BY32,Q9H2U2,Q9NUQ7,Q9UHD2,P49589,O14744,P06737,P12277,P30566,P42574,P28161,P50579,P53602,Q13614 275 +Transcription factors 0.2525617018501332 0.5956232296301219 0.5514269546348314 0.9999999511913672 1.0 70 Q03164,Q9UPT8,Q9BQ70,P85037,P67809 5 +RAS pathway related proteins 0.290342675013746 0.2834729806866991 0.7768142908661742 0.999999999999979 1.0 32 P62993,P21359,Q04206,Q13153,Q13043,Q13177,P19174,P60953,P61020,P36507,P31751,Q96KP1,Q9UHD2,Q02750,Q06124,P17612,P28482,O15111 18 +Plasma proteins 0.1417091101641463 0.2743198282019267 0.7838388480552159 0.9999999999999892 1.0 1310 Q03164,Q9UMX5,Q9UQB8,P17655,P25205,O75116,P25787,P48147,Q9BPU6,Q9UH99,Q9Y6B6,P62847,Q13126,O60942,O43396,P28070,P18858,Q01105,Q9Y263,P55786,Q14240,Q5VZE5,Q9H4M9,Q01844,P35269,P52888,Q15477,P49419,P42356,P67809,Q9Y613,P00813,O95067,Q9UBF2,Q9BZF3,Q92796,P49005,P41567,P35754,P23921,O15020,Q9UHG3,Q99996,Q9NTK5,Q9Y487,P26358,P30046,O00625,P61960,P67870,Q08209,P49903,P28340,P21359,O43847,Q15257,Q86X10,Q13144,Q9BSJ2,P08397,P07741,Q00796,O94919,P05387,P30086,P43490,P62899,Q9Y2L1,Q9UBP6,P15531,Q07864,P42858,P48634,Q00534,Q9Y620,O15067,P53999,P09012,O00170,Q14258,O14737,P61970,P78417,P78559,Q14353,Q7Z478,Q9NR09,Q9NY33,P68036,O00429,P17858,P09429,P19474,P31939,P40763,P49721,Q7LBC6,Q96T51,Q9Y666,Q14185,P20585,O60493,P49327,Q06124,Q13564,Q92616,Q7L014,Q7Z4Q2,Q86UV5,Q8NE71,Q92538,Q99986,Q9GZT9,Q9UKK9,Q9Y383,P28074,O60664,O75179,O75821,P13674,P14635,P18669,P20290,P26641,P27695,P29083,P60866,P31946,P62917,P60900,P53004,P42695,P41240,Q15008,Q15555,Q92614,Q9BTX7,Q9Y237,P11413,O14802,O60841,P09960,P00492,P19174,P42694,P48735,P49720,P53396,Q96IU4,Q96FW1,Q8IWV7,Q9BPW8,Q99873,Q9H4A4,Q9HAU5,Q9P2T1,Q6PKG0,O14965,O43776,O60294,O95163,P04350,P07437,P63241,P50851,P51003,P52701,P28482,Q9BWD1,Q9H2U2,Q14746,Q15020,Q15058,O14744,P06737,P12277,P35080,P42574,P50579,P53602,Q13200,Q14677,Q05639,Q00535,Q15369,Q9Y3Z3,Q9BUF5,P51784,P54136,P50748,P47755,O00487,O14981,O60333,O00299,O60701,O60725,O75874,P09972,P13693,P14618,P26196,P26639,P27635,P28066,P11802,P46063,Q92499,Q96AE4,Q92620,Q86VP6,Q15648,Q96TA1,Q99661,Q9BY44,Q9UKG9,P80303,Q9Y4B6,P55060,O00330,O75534,P04183,P13639,P13807,P14735,P14854,P17987,P18621,P53618,P26572,P51858,P51570,P48444,P50570,P45985,P43034,P30519,P26640,Q8TAG9,Q99575,Q92688,Q14204,Q15398,Q9Y295,Q9P2J5,Q9NQR4,Q9H6U6,Q9BXS5,Q6IBS0,O76094,P29692,P27708,P22314,P20618,O96017,P31350,O43505,O00401,P30520,P04075,P32969,P49915,Q05519,P35611,P62701,P62495,P51114,P48506,P47897,P45974,P41252,P39748,P39019,Q92974,Q8TEW0,Q8IYB3,Q8IV63,Q99439,Q9UKJ3,Q9NTJ3,Q9HD20,Q9HCE1,Q16513,O95336,P15880,P05198,P00491,O95801,O95373,O94966,P43487,O60610,O15347,O00203,P39023,P46109,P46783,Q15021,Q01813,Q15691,P62195,P52732,P48643,P47756,Q8N6T3,Q15056,Q14694,Q96KB5,Q9H1B7,Q9Y376,Q9Y617,Q14166,Q9HCK8,Q14008,P27348,P63104,O14818,O14980,P07814,P10155,P12268,P33176,P51452,P62269,P54577,P52209,P60981,P49368,P35579,Q92973,Q14203,Q13283,Q9Y5B9,Q96RQ1,Q04637,Q9Y5K5,Q9Y490,Q9UPY3,Q9UNN8,Q9UNF1,Q9NR31,Q13153,Q03001,P07900,P06730,P04080,P00568,O75351,O43264,O00764,P07737,A5YKK6,P15311,P21399,P68371,P62993,P62750,Q00341,P53621,P49643,P43686,P35251,P33981,P25789,Q8TD19 365 +Metabolic proteins 0.1911758082125587 0.2408710547906178 0.8096550566495382 0.9999999999999992 1.0 937 P11310,Q03164,Q05639,Q00535,Q8N4Q0,Q70HW3,O43772,Q7Z6Z7,O60502,Q9NPH0,Q99570,Q8NBX0,Q9BXJ9,Q9UNI6,P51784,O75116,P54136,Q9NW08,O95394,P27544,P48147,O60701,O60725,Q15392,O75874,O60566,P09972,P14618,Q9NQZ5,P26639,P49427,P33316,Q13126,P11802,O60942,Q96BP3,Q96RU2,Q15648,Q96SB4,P78362,Q9C0C9,Q9UPT9,Q9HCL2,Q9UKG9,Q99707,P31751,P61086,P55786,Q05086,O00330,O60678,Q7Z4G4,P04183,P13639,P13807,P14854,Q13535,Q8N1G2,P46976,P53618,P26572,P51570,P48444,Q9BZX2,P50570,P45985,P43034,P30519,P30154,P26640,P35269,P17812,Q96P11,Q93008,Q9NVE7,P52888,P49419,P42356,Q86W50,Q14527,Q9Y285,P34949,P00813,Q9P2J5,Q9NQR4,Q9P0J0,Q9Y5K8,Q99956,Q5TAX3,Q9UBF2,P27708,P22392,Q7L2J0,Q7Z2T5,Q16512,P49005,P22314,P35754,P23921,P22681,O96017,Q13572,Q9UHG3,P31350,O43505,O15111,O00743,O00442,Q06203,Q9Y487,P30520,Q99504,P04075,P49915,Q06210,P61081,P07099,P48506,P26358,P47897,P45974,P41252,P67870,Q969T7,Q08209,Q15386,P49903,P40818,P28340,O00154,P08397,Q01433,P07741,Q00796,P43490,Q9UBP6,Q9BV10,P15531,P35790,Q07864,Q00534,O15067,Q16763,P49761,P41440,P11172,Q96K76,Q8NCE2,P78417,Q14353,Q8WTV0,Q93100,Q9BUI4,Q96PE3,Q9BSD7,Q9NR09,Q9NR45,Q9UBT2,P68036,O00429,P17858,O14929,O43318,P08243,P31939,P19784,Q96EB6,Q15126,Q99426,Q9Y666,Q9UIA9,P00374,P48449,P49327,Q06124,Q13057,Q13564,Q7Z7E8,Q86UV5,Q99986,Q9UKK9,Q5VTR2,O60664,O95630,P13674,P18669,O75182,P63151,P53004,P41240,Q96C23,Q86TX2,Q8WUA2,Q96IJ6,Q9Y237,P11413,O14802,P08237,P09960,P00492,P19174,P36507,P48735,P53396,Q8IWV7,Q96AY3,Q99873,Q9H4A4,Q9NRN7,Q9NSD9,Q9P2T1,Q9ULT8,O15357,O14965,O43776,O60294,O95071,P20839,P30307,P51003,P28482,Q8TEA1,Q9BWD1,Q9BY32,Q9H2U2,Q9UHD2,P49589,O14744,P06737,P12277,P30566,P28161,P53602,Q13614 234 +Cancer-related genes 0.2018073902997669 0.1130372696143169 0.910001007676972 1.0 1.0 393 Q03164,P55210,P25205,Q7Z6Z7,O00299,O75874,O60566,P09972,P14618,P26196,P27635,P49427,P11802,Q96AE4,Q15382,Q8IWS0,Q15648,Q13617,Q99661,Q01105,P80303,P31751,P55212,P55060,O75534,P04183,P13639,Q14240,Q13535,P50570,Q01844,P67809,O95067,Q9UER7,P22681,Q99996,P07099,P67870,P40818,P28340,P21359,Q14790,P43490,Q9Y2L1,Q9HC35,Q92734,Q6W2J9,P15531,Q07864,Q00534,Q9Y620,P41440,P18074,Q14258,Q5VU43,Q9NR09,P16949,P31939,P40763,P19784,Q9H6R7,P00374,P20248,P49327,Q06124,P14635,P27695,P31946,Q13309,Q00653,P11413,O00221,P09960,P19174,P36507,P48735,P53396,Q96PU8,O15357,O14965,O95071,P63241,P30307,P52701,P28482,Q9H2U2,P49589,P12277,P42574 89 +FDA approved drug targets 0.2021037118855408 0.0635332365821924 0.9493418937293864 1.0 1.0 130 P00813,P20645,O75116,P78559,P20618,Q14353,P23921,Q00653,O75874,P00492,P36507,P11802,P48735,P53396,P26358,P31939,P49721,Q99707,P07437,P00374,P20839,P49327,P13639,P14735,P28482,P36404,Q07864,Q00534,P28074,P12277,O60664,P42574 32 +Ribosomal proteins 0.1097790918764133 0.0505784039052278 0.9596614719820292 1.0 1.0 122 P46776,P84098,P62750,P60866,P62917,P62906,P61254,P61247,P50914,P46778,P62081,P32969,P62701,P27635,P62847,P08708,P62854,Q7Z7F7,P42766,P39019,P62269,P61513,P47914,P83731,Q8TAE8,P05387,P62753,P18621,P62899,P15880,Q9HD33,P39023,P62266,P46783,P62841 35 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..847ed981932b102c30c4726cfce4084986e27cac --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANKRD46", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf174", "C1orf198", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "C5orf24", "C8orf33", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NEMP1", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", 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"TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR47", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZNF703", "ZNHIT2", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["AASDHPPT", "ABCF1", "ABHD14B", "ACADM", "ACAT2", "ACLY", "ACO1", "ACOT1", "ACOT7", "ACP6", "ADA", "ADD1", "ADPRHL2", "ADSL", "ADSS", "AIP", "AK1", "AKAP9", "AKT2", "ALDH7A1", "ALDOA", "ALDOC", "ALG12", "ALKBH5", "AMPD2", "ANKRD17", "ANP32B", "AP1M1", "AP3B1", "APEX1", "APRT", "ARCN1", "ARFGAP1", "ARHGEF2", "ARIH2", "ARL2", "ASCC3", "ASNS", "ATG4B", "ATIC", "ATP13A1", "ATP6V0A2", "ATP6V1D", "ATR", "AURKA", "B4GAT1", "BAIAP2", "BCAS3", "BCOR", "BIRC6", "BLVRA", "BTAF1", "BTF3", "BUB1B", "CAB39", "CAD", "CAND1", "CAPN2", "CAPZA2", "CAPZB", "CARS", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CCNA2", "CCNB1", "CCNB2", "CCT3", "CCT5", "CDC25C", "CDC34", "CDC42", "CDK4", "CDK5", "CDK6", "CERS1", "CHAC2", "CHD1", "CHD1L", "CHD8", "CHEK2", "CHKA", "CHUK", "CKAP5", "CKB", "CLIC1", "CLINT1", "CLK3", "CLPP", "CMTR1", "CNN2", "CNOT1", "COASY", "COG2", "COPA", "COPB1", "COPG2", "COPS5", "COPS6", "COX6B1", "CRKL", "CROT", "CSDE1", "CSE1L", "CSK", "CSNK2A2", "CSNK2B", "CSTB", "CTPS1", "CUL2", "DAXX", "DCAF1", "DCPS", "DCTN1", "DDT", "DDX1", "DDX28", "DDX46", "DDX6", "DHCR24", "DHFR", "DHX16", "DHX29", "DHX38", "DHX40", "DHX57", "DIAPH1", "DICER1", "DIS3", "DLG3", "DLGAP5", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPH2", "DPP3", "DPP9", "DPYSL5", "DRG1", "DST", "DSTN", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "EEF1A2", "EEF1D", "EEF1G", "EEF2", "EGLN1", "EHD1", "EIF1", "EIF2A", "EIF2B5", "EIF2S1", "EIF3G", "EIF4A2", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "EIF5B", "ELOC", "ELP1", "EML4", "ENDOD1", "EPHX1", "EPRS", "ERCC2", "ERCC6L", "ERGIC2", "ETF1", "EWSR1", "EXOC2", "EXOC6", "EYA3", "EZR", "FAM129B", "FARSA", "FARSB", "FASN", "FEN1", "FHOD1", "FKBP10", "FOXK1", "FTO", "FUBP1", "FXR1", "G3BP1", "G6PD", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GBF1", "GCLC", "GCN1", "GFPT1", "GLRX", "GMPPA", "GMPR2", "GMPS", "GPAM", "GPATCH8", "GRB2", "GSTM2", "GSTO1", "GTF2E1", "GTF2F1", "GYG1", "GYS1", "HAT1", "HDGF", "HDLBP", "HEATR3", "HECTD1", "HELZ", "HLTF", "HMBS", "HMGB1", "HMGB3", "HMOX2", "HPRT1", "HSP90AA1", "HTT", 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Q8N4Q0,Q9UID3,Q96C57,Q96GQ5,O95067,Q9BTX7,Q9Y6D5,Q14CX7,Q5VU43,Q93100,Q99996,Q9NR09,P22059,Q86VP6,Q9H4A4,P18858,P40818,O15357,P80303,Q96JB2,P50851,P52701,Q8TEA1,P24390,Q13535,P53618,P51570,P48444,P50570,Q92538,P36404,Q6P6C2,O95456,Q5VW32,Q14746,Q69YN2,Q8TD16,Q9UJY4,O95070,P26641 40 +Focal adhesion sites 0.1713383042646575 0.0539194932343597 0.9569993059013768 1.0 1.0 27 P49770,Q9NZ32,P36404,Q9Y487,O60888,Q14847,Q13418,Q96HC4,Q96AC1,Q9Y490,P12814 11 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bde3e9de88f61c006ea5f5ecae5d47565006efe0 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD46", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARID1A", "ARID2", 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"CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", 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"DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERH", "ERI1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGPS1", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXIM1", "HGH1", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLPH", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGA", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NEMP1", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PLXNA1", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE4", "TLN1", "TM9SF3", "TMA16", "TMED10", "TMED2", "TMEM126A", "TMEM126B", "TMEM165", "TMEM167A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI2", "TTK", "TTLL12", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR44", "WDR46", "WDR47", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR77", "WDR82", "WDR89", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFR", "ZFYVE16", "ZMYM3", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AAR2", "AARSD1", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD14B", "ABHD5", "ACAT2", "ACLY", "ACO1", "ACOT7", "ACP1", "ACTN1", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADD1", "ADD3", "ADRM1", "ADSL", "ADSS", "AHCY", "AHSA1", "AIP", "AK1", "AKAP9", "AKR1A1", "AKR7A2", "AKT1S1", "AKT2", "ALDH1B1", "ALDH7A1", "ALDOA", "ALDOC", "ALKBH5", "AMMECR1", "AMPD2", "ANKRD17", "ANP32B", "ANP32E", "AP1B1", "AP3D1", "APEX1", "APRT", "ARCN1", "ARFGAP1", "ARFGEF2", "ARL2", "ARMC8", "ARMT1", "ASCC3", "ASNS", "ATAD2", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATR", "AURKA", "BABAM2", "BAG6", "BAIAP2", "BCOR", "BICD2", "BIRC6", "BLVRA", "BLVRB", "BROX", "BTAF1", "BTF3", "BUB1", "BUB1B", "C12orf43", "C16orf58", "C17orf75", "C8orf33", "CAB39", "CACYBP", "CAD", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAPN2", "CAPZA2", "CAPZB", "CARS", "CASP3", "CASP6", "CASP8", "CBL", "CCDC124", "CCDC138", "CCDC22", "CCDC6", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCT3", "CCT4", "CD2AP", "CDC123", "CDC34", "CDC42", "CDC6", "CDCA2", "CDK4", "CDK5", "CDK6", "CENPI", "CEP170", "CHAC2", "CHD1L", "CHM", "CHUK", "CIAO1", "CIP2A", "CKAP2", "CKAP5", "CKB", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLTC", "CLUH", "CMTR1", "CNN2", "CNOT1", "CNOT2", "CNOT7", "COG2", "COG3", "COPA", "COPB1", "COPS2", "COPS5", "COPS6", "COPS8", "CRKL", "CROT", "CSDE1", "CSE1L", "CSK", "CSTB", "CTPS1", "CUL2", "CUL5", "CUTA", "CWC22", "CWF19L1", "DAXX", "DCAF1", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN3", "DCTPP1", "DDX1", "DDX20", "DDX28", "DDX6", "DHX16", "DHX29", "DHX38", "DHX40", "DHX57", "DIAPH1", "DICER1", "DIS3", "DLG3", "DLGAP5", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJC13", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPH2", "DPP3", "DPP9", "DPYSL5", "DRG1", "DRG2", "DST", "DUS1L", "DUSP12", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "ECD", "ECT2", "EDC3", "EDC4", "EDRF1", "EEF1A2", "EEF1G", "EEF2", "EFL1", "EHD1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF3A", "EIF3D", "EIF3G", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELOC", "ELP1", "ELP2", "ELP3", "EML4", "EPRS", "ERCC2", "ERCC6L", "ESD", "ESF1", "EWSR1", "EXO1", "EXOC2", "EXOC6", "EYA3", "FAH", "FAM120A", "FAM120B", "FAM129B", "FAM208B", "FAM98A", "FARSA", "FARSB", "FASN", "FBXO7", "FERMT2", "FHOD1", "FLAD1", "FLII", "FLYWCH2", "FMR1", "FOXK1", "FTO", "FTSJ1", "FUBP1", "FXR1", "FXR2", "G3BP1", "G6PD", "GALK1", "GALM", "GAPVD1", "GARS", "GBF1", "GCLC", "GCLM", "GCN1", "GDE1", "GDI2", "GEMIN5", "GET4", "GFPT1", "GGA2", "GIGYF2", "GINS4", "GLMN", "GLOD4", "GLRX", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNL1", "GOLT1B", "GPI", "GPKOW", "GSTCD", "GSTM2", "GTF2E1", "GTF2F1", "GTF2F2", "GTPBP1", "GYG1", "GYS1", "HAT1", "HAUS6", "HBS1L", "HDGFL2", "HDHD2", "HDLBP", "HEATR3", "HECTD1", "HELZ", "HLTF", "HMBS", "HMCES", "HMGB1", "HMOX2", "HPRT1", "HS1BP3", "HSP90AA1", "HSP90AB1", "HSPH1", "HTT", "HUWE1", "IAH1", "IARS", "IDH1", "IGBP1", "IGHMBP2", "ILK", "IMPDH1", "IMPDH2", "INPP4A", "INPPL1", "INTS5", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "ITPA", "KDELR1", "KDM3B", "KIAA0368", "KIAA0391", "KIAA1671", "KIF11", "KIF14", "KIF1B", "KIF20B", "KIF2C", "KIF5B", "KLC2", "KMT2A", "KNTC1", "KPNA4", "LARP1", "LARS", "LASP1", "LCMT2", "LDHA", "LIG1", "LRBA", "LRCH2", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LYPLA1", "LZIC", "MAGED2", "MAP1A", "MAP1S", "MAP2K2", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MCM3", "MCMBP", "MCTS1", "MCUB", "ME1", "MED1", "MEPCE", "METAP2", "METTL1", "METTL16", "MGEA5", "MID1", "MKLN1", "MMS19", "MOCS1", "MON2", "MOV10", "MPG", "MPI", "MPP1", "MRRF", "MSH3", "MSH6", "MSTO1", "MTAP", "MTBP", "MTMR2", "MTR", "MVD", "MYG1", "MYH9", "NAA15", "NAA25", "NAA35", "NAE1", "NAF1", "NAGK", "NANS", "NAP1L1", "NAPA", "NARS", "NARS2", "NCAPD2", "NCAPD3", "NCAPH", "NCAPH2", "NCDN", "NCKIPSD", "NECAP1", "NELFCD", "NELFE", "NEMP1", "NFATC2IP", "NFKB2", "NFKBIE", "NIT2", "NME1", "NME2", "NOSIP", "NPEPPS", "NPLOC4", "NPM3", "NR2F1", "NRDC", "NSRP1", "NSUN2", "NSUN6", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUDCD1", "NUDT21", "NUDT5", "OCRL", "ODR4", "OLA1", "ORC3", "OSBP", "OSBPL3", "OSBPL6", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "P4HA1", "PA2G4", "PABPC4", "PAFAH1B1", "PAK1", "PANK4", "PAPOLA", "PARD3", "PATJ", "PATL1", "PAWR", "PBK", "PDCD5", "PDE4DIP", "PDHX", "PDLIM5", "PEBP1", "PFAS", "PFDN5", "PFKP", "PFN1", "PGAM1", "PGD", "PGLS", "PGM1", "PGM3", "PHAX", "PHF6", "PHKB", "PI4KA", "PIAS1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLPBP", "PMF1", "PMS1", "PNMA8A", "PNP", "POLD1", "POLD2", "POLE", "POLR3A", "POLR3C", "PPIL4", "PPME1", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP6R3", "PPWD1", "PREP", "PRKACA", "PRKRA", "PRMT1", "PRMT5", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSAT1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB2", "PSMB4", "PSMB5", "PSMC1", "PSMC4", "PSMC5", "PSMC6", "PSMD10", "PSMD14", "PSMD3", "PSMD4", "PSME3", "PSME4", "PSMG1", "PSMG2", "PTGR2", "PTPA", "PTPN11", "PUDP", "PYGL", "QARS", "QKI", "QRICH1", "RAB3GAP1", "RABGAP1", "RANBP1", "RANBP9", "RARS", "RDX", "RECQL", "RELA", "REPS1", "RIC8A", "RIPK1", "RMDN3", "RNASEH2A", "RNF20", "RNGTT", "RNPEP", "ROCK2", "RPAP1", "RPL10", "RPL10A", "RPL14", "RPL17", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27A", "RPL29", "RPL3", "RPL35", "RPL37A", "RPL4", "RPL8", "RPL9", "RPLP2", "RPP40", "RPS10", "RPS15", "RPS17", "RPS18", "RPS2", "RPS20", "RPS23", "RPS24", "RPS26", "RPS3A", "RPS6", "RPS7", "RPS8", "RRM1", "RRM2", "RUFY1", "SAE1", "SAMD4B", "SAMHD1", "SARS", "SART3", "SBNO1", "SCARB1", "SCCPDH", "SDCBP", "SEC24B", "SEC31A", "SEPHS1", "SEPT6", "SET", "SH3PXD2B", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKP2", "SLC12A7", "SLC19A1", "SLC25A20", "SLFN11", "SLK", "SMARCAD1", "SMC4", "SMG5", "SMN1*", "SNRPA", "SNX17", "SNX5", "SORD", "SPAG9", "SPART", "SPC25", "SPTBN2", "SQSTM1", "SRM", "SRP68", "SRPK1", "SRPK2", "SSB", "STAMBP", "STAT3", "STK4", "STMN1", "STRAP", "STRIP1", "SUB1", "TARS", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBK1", "TDP1", "TDRD7", "TFG", "THOP1", "THUMPD3", "THYN1", "TIMM17B", "TLE4", "TLN1", "TNPO1", "TNPO3", "TOMM34", "TOPBP1", "TPP2", "TPT1", "TRAPPC11", "TRIM21", "TRIM25", "TRIP13", "TRMT11", "TRMT1L", "TRMT6", "TROVE2", "TSTA3", "TTC1", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TWF2", "TXNL1", "UAP1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBL7", "UBR1", "UBR4", "UBR5", "UBXN1", "UCHL5", "UCK2", "UFSP2", "UGDH", "UMPS", "UNC45A", "UPF1", "UPF2", "URGCP", "USP10", "USP11", "USP28", "USP47", "USP48", "USP5", "USP8", "USP9X", "VAC14", "VARS1", "VPS51", "VRK1", "WAPL", "WARS", "WASHC4", "WASL", "WBP2", "WDCP", "WDR4", "WDR47", "WIPI2", "WRAP53", "XPNPEP1", "XPO1", "XPO5", "XRN1", "YARS", "YBX1", "YIF1A", "YTHDC2", "YWHAB", "YWHAQ", "ZADH2", "ZC3H4", "ZC3H7A", "ZCCHC11", "ZCCHC3", "ZFP91", "ZFYVE16", "ZW10"]} \ No newline at end of file