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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Sphingolipid metabolism 0.7163246697021323 3.872048819649177 0.0001079243281145 0.1393117437058745 0.1412578927747672 26 Q9NZJ7,P04062,Q16739,Q96G23,O95470,O15269,P51648,P07602,P15289,P10619,P27544,Q06136,Q13510,P16278 14
Metabolism of steroids 0.5572769532737898 3.7149439183513855 0.0002032487665823 0.2461369056441852 0.1412578927747672 50 O95487,Q16850,P04035,Q9BZF3,Q15392,Q53GQ0,P04062,Q14739,Q14534,O75845,Q9BWD1,Q8NBQ5,Q15125,O95749,Q9HCL2,Q15800,Q9Y6B6,P30536,P37268,O00767,Q14849,P38435 22
Protein localization 0.4631949386267718 3.507555778016953 0.0004522435350513 0.4667477493019489 0.1720733456116011 77 O60830,Q9BY49,Q99595,P46379,P21796,P09601,P60059,O43615,P12236,Q9NS69,Q9Y584,O43933,Q8N4H5,Q10713,P50402,P28288,P56589,O43808,Q15067,Q13190,O14925,P51648,Q9NR77,O15254,Q9Y5L4,Q13505 26
Slc mediated transmembrane transport 0.7284118158385751 3.433439847554498 0.0005959744264529 0.5633622630140204 0.1720733456116011 20 P05141,Q8TB61,Q70HW3,Q9UBX3,P53985,P55011,P12236,Q9Y289,P11166,P35613,Q9Y666 11
Cholesterol biosynthesis 0.6866369874478855 3.099499036866488 0.0019384820809857 0.9325996509912278 0.1720733456116011 19 Q16850,Q14739,P04035,Q14534,O75845,Q15800,Q15392,Q15125,P37268 9
Glycosphingolipid metabolism 0.7335860160648493 2.998877398268621 0.0027097632368981 0.976986709792378 0.1883285449644249 15 Q9NZJ7,Q16739,P04062,P10619,P15289,P07602,Q13510,P16278 8
Ion channel transport 0.5312558319949303 2.624559362993309 0.0086761167039119 0.999994509124962 0.2865871908957905 29 Q9Y487,P51790,P98194,Q9NW15,Q9HD20,P16615,Q15904,Q93050,Q8NB49,Q13555,Q9C0H2,Q4KMQ2 12
Mitochondrial protein import 0.5030618975490975 2.598422967941275 0.0093653055369198 0.9999979116070272 0.2865871908957905 34 O60830,Q99595,Q8N4H5,P21796,Q10713,O43615,Q9NS69,Q9Y584,Q9Y5L4,Q13505,O14925 11
Mitochondrial calcium ion transport 0.6170335825746962 2.5329444642528944 0.0113108871607265 0.9999998641514272 0.2911506139520364 18 Q9Y277,Q9H300,P21796,Q8IYU8,Q10713,O95202,P45880,Q9NWR8 8
Sphingolipid de novo biosynthesis 0.7381888273008613 2.515613402649844 0.0118825443252761 0.9999999391985008 0.2921988549903104 11 Q96G23,O95470,P51648,P27544,Q06136 5
Transport of inorganic cations anions and amino acids oligopeptides 0.7840997627776859 2.5065242263456984 0.0121924702082287 0.999999960686477 0.2921988549903104 9 Q70HW3,Q9Y666,Q9UBX3 3
Ire1alpha activates chaperones 0.5262753354916923 2.3424427217206447 0.0191579743749568 0.9999999999978976 0.3916115350174995 25 Q9Y5M8,P43307,P49748,O14773,O95070,Q9UBS4 6
Stimuli sensing channels 0.7430501436317584 2.30584506166999 0.0211192913115396 0.99999999999987 0.3967002016627046 9 Q9C0H2,P51790,Q4KMQ2 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.8244734518528468 2.2940827330941747 0.0217857469789812 0.9999999999999496 0.3984498460629471 6 P04035,Q16850,Q9NR77 3
Transport of small molecules 0.4477162093651854 2.2592730475900784 0.023866405391268 0.9999999999999972 0.4199278923273746 153 P02786,P05141,P28070,O75027,Q8IWT6,Q70HW3,P21796,P30519,Q15904,O15118,P09601,Q9UEY8,P12236,Q8NB49,P45880,Q9NWR8,P49721,O94973,Q9Y487,P12235,Q8N4V1,P51790,Q8TB61,Q99797,Q00610,Q10713,P28072,Q96TA2,Q15008,Q9Y277,P28288,Q8NE71,P98194,Q8WTV0,P56589,P16615,Q9UBX3,Q93050,Q8IYU8,Q9Y6B6,P55011,O95202,Q13555,Q14997,P11166,Q9UBV2,P35613,Q9C0H2,Q9Y666,Q4KMQ2,Q6PIU2,Q9H300,Q9BUN8,Q9NW15,Q9HD20,P08183,P53985,Q9Y289,Q8WWC4,Q9Y5K8,Q8TDW0 61
Glycosaminoglycan metabolism 0.6260449150571765 2.247215765752645 0.024626241089948 0.9999999999999992 0.4225984582102194 14 P54802,Q8TB61,Q7LGA3,Q8NCH0,P16278 5
Metabolism of porphyrins 0.7051479887024925 2.1821241986734665 0.0291003677128061 1.0 0.4544888889977583 10 P30519,P09601 2
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.5267576770544926 2.145777345114197 0.0318907469346068 1.0 0.4569911158670459 22 Q86YN1,O75352,Q9BT22,Q9BV10,P10619,Q9Y223,Q2TAA5,P16278 8
Regulation of cholesterol biosynthesis by srebp srebf 0.4815912487857415 2.129053651529238 0.0332498217932788 1.0 0.4629095150396074 27 Q9HCL2,Q16850,O00767,P04035,Q14534,O75845,Q9Y6B6,P37268,O95749 9
Mitophagy 0.6206980676453585 2.123015551869181 0.0337525486762508 1.0 0.4645152738612745 13 P67870,Q8N4H5,O96008,P21796,Q9NS69,Q8IWA4,Q13501 7
Peptide ligand binding receptors 0.7820779182626472 2.1056227179024596 0.0352371376771798 1.0 0.4755303045755337 6 P07602,P42892 2
Class a 1 rhodopsin like receptors 0.7820779182626472 2.1056227179024596 0.0352371376771798 1.0 0.4755303045755337 6 P07602,P42892 2
Diseases of glycosylation 0.5278387026476441 2.098590817932794 0.0358529864739591 1.0 0.4791889538346467 21 O60762,O75352,Q96L58,Q9BT22,Q9BV10,P10619,O43505,Q9Y223,Q2TAA5,Q8NCH0,P16278 11
Miscellaneous transport and binding events 0.778471404108417 2.0894172193521863 0.0366701825155435 1.0 0.4854433685391003 6 Q8N4V1,Q8TDW0,Q9UEY8 3
Class i peroxisomal membrane protein import 0.6829348262168793 2.0667634736278258 0.0387564468590171 1.0 0.5082213314531493 10 P56589,Q9NR77,O43808,P51648 4
Pink1 prkn mediated mitophagy 0.6882263545304126 2.0308111339107113 0.042274157158324 1.0 0.5256326777787211 9 P21796,Q9NS69 2
Synthesis of very long chain fatty acyl coas 0.6978535953792493 2.0240899877929253 0.0429608936027294 1.0 0.5284570098034865 8 Q9P035,Q6Y1H2,Q53GQ0 3
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6138063900389445 2.0013163330638664 0.0453583106883273 1.0 0.540625905551718 12 P46379,P51648,P60059,P09601,P50402,Q13190 6
Cargo concentration in the er 0.56723957131791 1.9768169854611408 0.0480623210263897 1.0 0.5435957202024041 15 O95487,Q12907,O95486,Q9HCU5,O14653,Q15363,Q9Y6B6,P49257,P49755,Q13190 10
E2f enabled inhibition of pre replication complex formation 0.7515729325369753 1.967715647556814 0.0491007643991201 1.0 0.5435957202024041 6 Q9UBD5,Q9Y619,P14635,P06493 4
Initiation of nuclear envelope ne reformation 0.5343415279802475 1.9631617048187755 0.04962738754464 1.0 0.5435957202024041 18 P14635,Q8IXJ6,Q86XL3,Q14739,P50402,O95067,P06493 7
Phase i functionalization of compounds 0.5775023733268663 1.9473510151292768 0.0514926664853414 1.0 0.5435957202024041 14 Q16850,P16435,Q86WA6,P07099,O43169,O00170 6
Metabolism of fat soluble vitamins 0.8015819472225703 1.9442233248626224 0.0518685262113511 1.0 0.5435957202024041 5 P29375,Q8N0U8 2
Hs gag degradation 0.9716587112171844 1.943208617032565 0.0519909573669086 1.0 0.5435957202024041 2 P16278 1
Pre notch processing in golgi 0.9015219337511152 1.935090534204839 0.0529791868973479 1.0 0.5435957202024041 3 Q9UBV2,Q15363 2
Fatty acyl coa biosynthesis 0.5604992803898275 1.9331182125791504 0.0532216369803892 1.0 0.5435957202024041 15 P53007,O00767,O95573,Q9P035,P50897,Q6Y1H2,Q9NZ01,Q53GQ0 8
Heparan sulfate heparin hs gag metabolism 0.7980652479168309 1.929123917108368 0.0537154804816919 1.0 0.5435957202024041 5 P54802,P16278 2
Heme degradation 0.8640300750437735 1.928032937217351 0.0538510294495342 1.0 0.5435957202024041 4 P30519 1
Transport of vitamins nucleosides and related molecules 0.677117600194378 1.9209077616852304 0.0547433370746159 1.0 0.5435957202024041 8 P05141,Q9Y289,Q8TB61,P12236 4
Alpha oxidation of phytanate 0.7954211927908488 1.917757838048384 0.0551417241356395 1.0 0.5435957202024041 5 Q9BY49,O43808,P51648 3
Synthesis of pc 0.7371988461053721 1.9020907327240584 0.0571592938012333 1.0 0.5595170308712274 6 P67870,P35790,Q9NQZ5,Q8NF37 4
Glycerophospholipid biosynthesis 0.4393246485443819 1.882065208907497 0.0598271624160231 1.0 0.5611214408900548 31 P67870,Q9HCL2,Q9NPH0,P48651,P35790,Q8NF37,Q9NQZ5,Q8NCC3,Q92604,Q8IV08 10
Activation of gene expression by srebf srebp 0.5048859724258509 1.877342457689894 0.0604711726035067 1.0 0.5611214408900548 20 Q9HCL2,Q16850,P04035,Q14534,P37268 5
Rnd1 gtpase cycle 0.5504989785399638 1.8679881193822652 0.0617637269468909 1.0 0.5611214408900548 15 Q9UIW2,P02786,P38159,P51648,Q15058,Q03001,Q9ULH0,Q9NNW5,Q14254 9
Mucopolysaccharidoses 0.8814338587099089 1.8567929669748968 0.0633406147099173 1.0 0.5643811182486227 3 P16278 1
Iron uptake and transport 0.5072629952020319 1.8521480212874035 0.0640045703842431 1.0 0.5666646677331079 19 Q9Y487,P30519,Q15904,Q93050 4
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6110108835866735 1.8244012932429805 0.0680914266379799 1.0 0.586271190624911 11 Q9BU89,O60725,P38435 3
Diseases associated with n glycosylation of proteins 0.6831338070701805 1.8140888664567103 0.0696640453564563 1.0 0.586271190624911 7 Q9BV10,Q2TAA5,O75352,Q9BT22 4
Diseases of carbohydrate metabolism 0.6524169268817748 1.796685256707943 0.0723856008284857 1.0 0.5883975739859371 8 P54802,P16278 2
Unfolded protein response upr 0.3940550140353152 1.738616291519845 0.0821022789413699 1.0 0.6044260661692161 41 Q9Y5M8,P43307,Q9NQT5,P49748,O14773,O95070,Q9UBS4,O95453 8
Gpcr ligand binding 0.616896201290165 1.716215471700163 0.0861226124845018 1.0 0.616969529989572 10 P07602,Q9NZJ7,P42892 3
Regulation of mecp2 expression and activity 0.6233988409164243 1.695855308666984 0.0899132850791706 1.0 0.6248973313002358 9 Q9HCE1,P42858,Q14739 3
Copi dependent golgi to er retrograde traffic 0.3695161140821158 1.6819949166523316 0.0925698256380014 1.0 0.6283982885811812 50 Q9Y496,P24390,Q15363,Q9P2W9,Q9Y3B3 5
Rhoa gtpase cycle 0.3792204284767124 1.655074484199862 0.0979093899511531 1.0 0.6372734052777763 44 P02786,P28288,P46940,Q96CS3,O75116,Q14739,P30519,Q15904,P51572,P61586,P49257,Q96HY6,O15173,O75955,Q13190 15
Transport of bile salts and organic acids metal ions and amine compounds 0.8970763723150377 1.6406821282432824 0.1008634166626696 1.0 0.6372734052777763 2 P53985 1
Proton coupled monocarboxylate transport 0.8970763723150377 1.6406821282432824 0.1008634166626696 1.0 0.6372734052777763 2 P53985 1
Sialic acid metabolism 0.721905406172316 1.597491641873202 0.1101561593008253 1.0 0.6380060659827591 5 P10619,P16278 2
Bile acid and bile salt metabolism 0.6115564627297585 1.5883654858953693 0.1122037172765799 1.0 0.6380060659827591 8 Q9H4L5,Q9BZF3 2
Synthesis of bile acids and bile salts 0.6115564627297585 1.5883654858953693 0.1122037172765799 1.0 0.6380060659827591 8 Q9H4L5,Q9BZF3 2
Intra golgi traffic 0.5310365248506026 1.5758244401176464 0.1150662682842988 1.0 0.6380060659827591 13 Q8TBA6,O00461,O95249,Q14746,O14653,Q9NRW7,Q13190 7
Wax and plasmalogen biosynthesis 0.7767164179104492 1.5735557763065482 0.1155901839897446 1.0 0.6380060659827591 4 Q8WVX9,O00116,Q6IAN0 3
Metabolism of folate and pterines 0.5994398307087563 1.5697606498528245 0.1164708053686163 1.0 0.6380060659827591 9 Q9H2D1 1
Intra golgi and retrograde golgi to er traffic 0.3408111762629755 1.559238289294735 0.1189399915138162 1.0 0.6380060659827591 92 P24390,Q9Y496,O14653,P49755,Q9Y3B3,Q15042,Q8TD16,Q96Q89,O14579,O95249,P61923,O60333,Q9Y678,Q9NRW7,P20645,O00461,O15260,P52732,Q14746,Q10472,Q14203,Q96JB2,Q13190,Q14204,Q9UID3,Q9H0U4,Q5VZE5,Q5VIR6,Q8TBA6,Q92538,Q9UJW0,O43237,Q15363,Q9P2W9 34
Aryl hydrocarbon receptor signalling 0.8050145772772146 1.554929009271525 0.1199629775595183 1.0 0.6380060659827591 3 O00170 1
Hdms demethylate histones 0.5956891063498855 1.5499282370493617 0.1211587413620822 1.0 0.6380060659827591 9 Q9UPP1,O75151,P29375,O60341 4
Inflammasomes 0.659109154651639 1.5391948667444 0.123756730438048 1.0 0.6380060659827591 6 P09601 1
The nlrp3 inflammasome 0.659109154651639 1.5391948667444 0.123756730438048 1.0 0.6380060659827591 6 P09601 1
Activation of the pre replicative complex 0.4601613282185488 1.538488427873745 0.1239292358383776 1.0 0.6380060659827591 20 P25205,Q07864,Q9UBD5,Q9NR33,Q14566,P33991,Q9Y619,P35244 8
Condensation of prometaphase chromosomes 0.5593062481023832 1.5307392365043704 0.1258338524398852 1.0 0.639878727512889 11 P67870,P14635,Q9NTJ3,P68400,Q15021,O95067,P06493 7
Vitamin d calciferol metabolism 0.7970753984278977 1.5232766780497944 0.1276894993958057 1.0 0.639878727512889 3 P38435 1
Acyl chain remodelling of pg 0.8678400954653929 1.52108720072438 0.1282379559741733 1.0 0.639878727512889 2 Q8NF37 1
Ion transport by p type atpases 0.5794411526382635 1.5130651655328728 0.1302631068790489 1.0 0.639878727512889 10 Q9HD20,Q13555,P16615,Q8NB49 4
Nr1h2 and nr1h3 mediated signaling 0.699151106958218 1.4969682336007832 0.1344015239421878 1.0 0.6506172928088132 5 Q9HCE1,O60341,O00767 3
Cation coupled chloride cotransporters 0.8615751789976152 1.4954227053483908 0.1348041585100274 1.0 0.6506172928088132 2 Q9Y666 1
Attachment of gpi anchor to upar 0.7893823947196612 1.4925682732393624 0.1355502334089628 1.0 0.6519544098216554 3 O43292 1
Phosphorylation of emi1 0.7866308564607587 1.4815767781752485 0.1384529417000117 1.0 0.6568245357099535 3 P14635,P06493 2
Abc transporters in lipid homeostasis 0.7839450910175969 1.4708442455415909 0.1413332436457268 1.0 0.6599607659211358 3 P56589,P28288 2
Formation of fibrin clot clotting cascade 0.7743957027752778 1.4326571121739249 0.1519558516020307 1.0 0.688008578914732 3 P42785,Q9UNN8 2
Synthesis of pe 0.8433770883054929 1.420846039186061 0.15536152305999 1.0 0.6902095689298234 2 P35790 1
Phospholipid metabolism 0.3426839439667425 1.3927000757339494 0.1637105057089094 1.0 0.7041859863654055 53 P67870,Q9NZC3,Q08AM6,Q9HCL2,Q8TBX8,Q9NPH0,P48651,Q10713,P42356,Q8NF37,Q9NQZ5,O00443,Q8NCC3,P35790,Q8IV08 15
Ras processing 0.7306916605619523 1.3837873120307371 0.1664235892140952 1.0 0.7041859863654055 4 O60725 1
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7615637123246668 1.3812908167326907 0.1671895606646942 1.0 0.7041859863654055 3 Q9HCE1,O60341 2
Metabolism of lipids 0.4101901361095134 1.3786952543955613 0.1679887332982768 1.0 0.7041859863654055 200 Q9BY49,Q9NZJ7,O95487,Q16850,O43772,P04035,O15269,P49748,Q9BZF3,Q9UG56,Q15392,O95864,P15289,O00116,P16278,Q53GQ0,P04062,P23786,P67870,Q14739,Q9H4L5,Q14534,O75845,Q10713,Q14914,P07602,Q9BWD1,Q9P035,Q15125,Q8NBQ5,P50897,Q9NQZ5,A0FGR8,Q8NF37,Q8NCC3,P35790,Q92604,O95749,Q6IAN0,Q16739,Q9NZC3,Q08AM6,Q9HCL2,Q8TBX8,Q9NPH0,P48651,Q15800,O43808,P10619,Q15185,Q9Y6B6,P27544,P30536,Q8WTS1,P37268,Q9BTU6,Q15067,O00443,Q9NXE4,Q9Y2X0,Q96G23,O95470,O00767,O75448,P51648,P42356,O15254,Q06136,Q6Y1H2,Q9NZ01,Q13510,Q14849,P38435,Q8IV08 74
Nephrin family interactions 0.5685870028857889 1.366324609897532 0.1718370999517757 1.0 0.709988732890114 8 Q01082,P46940,Q13813,Q9Y5K6 4
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.7125742979482435 1.308825264595739 0.1905935468172204 1.0 0.7379527300165358 4 Q14185 1
Basigin interactions 0.547632747905785 1.2574003529792637 0.2086087014885822 1.0 0.7701970989149188 8 P53985 1
Polo like kinase mediated events 0.5694087959387224 1.252417449745252 0.210417791145075 1.0 0.7701970989149188 7 P14635,P49454,P53350 3
Signaling by flt3 fusion proteins 0.6987592085956686 1.2516480229058728 0.2106981475162692 1.0 0.7701970989149188 4 Q92614,Q14789 2
Processing of smdt1 0.4783984675165543 1.2460795172254615 0.2127352037648335 1.0 0.7701970989149188 13 Q9H300,Q10713,Q8IYU8,Q8WWC4,Q9NWR8 5
Translation of sars cov 2 structural proteins 0.4345283024075841 1.2422139126583762 0.2141576478163158 1.0 0.7730365474341874 18 P04844,P04843,P46977,Q13724,P26572,P27824,P48729,P78362 8
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3187402202052323 1.2392710139182452 0.215245149436225 1.0 0.7731027331171908 64 Q86Y39,Q5RI15,O14949,Q8TB37,P00403,Q9Y6N1,Q9P0J0,O75964,O43676,P56134,Q9UDW1,O75880,P24539,Q9NPL8,Q8IUX1 15
Respiratory electron transport 0.3285419836404245 1.2333713670892106 0.2174372425791246 1.0 0.776960841092502 54 Q86Y39,Q5RI15,O14949,Q8TB37,P00403,Q9Y6N1,Q9P0J0,O75880,O43676,Q9NPL8,Q9UDW1,Q8IUX1 12
Insulin receptor recycling 0.5059707432907209 1.2233421929463622 0.2212004771671138 1.0 0.7782462020069807 11 Q9Y487,Q93050 2
Regulation of tp53 expression and degradation 0.4836061357146745 1.2194727402976302 0.2226648161245368 1.0 0.7782462020069807 12 P42771,Q9UER7,P42345,P06493 4
Role of phospholipids in phagocytosis 0.6867630028097544 1.2020273809206872 0.2293529197890318 1.0 0.7793071341679677 4 Q8IV08 1
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.632405148067946 1.2002090584267124 0.2300581581652487 1.0 0.7793071341679677 5 P12235,P05141,P12236 3
Synthesis of substrates in n glycan biosythesis 0.443422635259684 1.197815434339468 0.2309888771778436 1.0 0.7793071341679677 16 Q86YN1,P10619,Q9Y223,P16278 4
Transferrin endocytosis and recycling 0.4773383166474008 1.1812826494138446 0.2374904575860656 1.0 0.7853554683034737 12 Q9Y487,Q93050 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.432679675924342 1.1721584937187894 0.2411334290997113 1.0 0.7853554683034737 17 Q9NZ08,Q9Y6B6,P51572,Q03519,Q03518 5
Noncanonical activation of notch3 0.7822195704057324 1.170955147309504 0.2416168064475181 1.0 0.7853554683034737 2 P67809 1
Nrif signals cell death from the nucleus 0.7822195704057293 1.1709551473094917 0.241616806447523 1.0 0.7853554683034737 2 Q13501 1
Synthesis of pips at the late endosome membrane 0.6770542174517304 1.161912684935397 0.2452709339791083 1.0 0.7898330856696498 4 Q08AM6 1
Regulation of lipid metabolism by pparalpha 0.3977682759007871 1.1294096565982772 0.2587250611049367 1.0 0.7956568529611061 22 Q9Y2X0,P23786,P04035,P37268,Q15067 5
Synaptic adhesion like molecules 0.5441770554124344 1.1264851886350948 0.2599602064129815 1.0 0.7956568529611061 7 P41440,O95197,O75955 3
G2 m dna replication checkpoint 0.6664790405916875 1.118288770996174 0.2634436811864207 1.0 0.7956568529611061 4 P14635,P06493 2
Vitamin c ascorbate metabolism 0.694900159283195 1.1146108214966102 0.2650172310209913 1.0 0.7956568529611061 3 P11166 1
Signaling by insulin receptor 0.4218921300933371 1.0959836459961416 0.2730859314130534 1.0 0.7962374156387224 17 Q9Y487,Q93050 2
Keratan sulfate keratin metabolism 0.6068158873665733 1.0865520349129827 0.2772348326358675 1.0 0.7962374156387224 5 P16278 1
Maturation of sars cov 2 spike protein 0.4820387601709684 1.0852810562006925 0.2777971935331194 1.0 0.7962374156387224 11 P04844,P46977,Q13724,P26572,P27824,P04843 6
Rac2 gtpase cycle 0.3388215915090936 1.0807511664072844 0.2798078161978878 1.0 0.7962374156387224 36 Q9Y2A7,Q14739,Q14185,O15173,Q13505 5
Synthesis of pa 0.4997496636656702 1.0759258984395184 0.2819603982599441 1.0 0.7962374156387224 10 Q9HCL2 1
Activation of atr in response to replication stress 0.3908092593005229 1.0742745017238329 0.2826996696906674 1.0 0.7962374156387224 22 P25205,Q9UBD5,Q13535,O60921,Q14566,P33991,Q9Y619,P35244 8
Peroxisomal lipid metabolism 0.4392046898765525 1.059232643214543 0.2894938420428961 1.0 0.7962374156387224 14 Q9BY49,O14975,O43808,P51648,O15254,Q15067 6
Er to golgi anterograde transport 0.2908029515065952 1.0566658404548923 0.2906641201781186 1.0 0.7962374156387224 80 P24390,O95487,O14653,P49755,Q9Y3B3,O14579,O75935,O95249,O95486,Q9HCU5,P84085,P61923,O15084,Q9Y678,Q13813,Q14746,Q9Y6B6,P49257,Q14203,Q96JB2,Q14204,Q13190,Q9H0U4,Q14789,Q92538,Q12907,Q9UJW0,O43237,Q15363,Q01082 30
Regulation of gene expression in beta cells 0.7532816229116965 1.0539967271819877 0.2918844155426718 1.0 0.7962374156387224 2 O00330 1
Cd28 dependent pi3k akt signaling 0.7532816229116965 1.0539967271819877 0.2918844155426718 1.0 0.7962374156387224 2 P42345 1
Glycogen storage diseases 0.675886910519319 1.039093206203206 0.2987613902849761 1.0 0.810279495556994 3 P46976 1
Diseases of metabolism 0.3168738904049511 1.015721773760886 0.3097618963445998 1.0 0.834436116122081 46 P54802,O60762,P46976,O75352,Q9BT22,Q9BV10,Q99707,P10619,O43505,Q9Y223,Q2TAA5,Q8NCH0,P16278 13
Wnt mediated activation of dvl 0.6654729931363632 0.9979449075193771 0.3183060742355676 1.0 0.8477144349439012 3 P67870,P68400 2
Cytoprotection by hmox1 0.2952935792884094 0.9726192101364712 0.3307425914999047 1.0 0.8535978496352544 66 P28070,P67870,Q5RI15,Q8TCT9,P00403,P30519,O75880,P09601,P28072,Q14997,P49721 11
Transport to the golgi and subsequent modification 0.2868625073495857 0.966619333840645 0.3337343658602565 1.0 0.8535978496352544 82 P24390,O95487,O14653,P49755,Q9Y3B3,O14579,O75935,O95249,O95486,Q9HCU5,P84085,P61923,O15084,Q9Y678,Q13813,P26572,Q14746,Q9Y6B6,P49257,Q14203,Q96JB2,Q14204,Q13190,Q9H0U4,Q14789,Q92538,Q12907,Q9UJW0,O43237,Q15363,Q01082 31
Sema4d induced cell migration and growth cone collapse 0.4911171054071463 0.9643472189545084 0.3348718747874817 1.0 0.8535978496352544 8 P08134,O75116,P35580,P35579,P61586 5
Visual phototransduction 0.5114805264730959 0.9641892014228696 0.3349510773016846 1.0 0.8535978496352544 7 P30419,P53582,P29375 3
Cdc6 association with the orc origin complex 0.5790607092404616 0.96414356130557 0.3349739555667703 1.0 0.8535978496352544 5 Q9UBD5,Q9Y619 2
Cytochrome p450 arranged by substrate type 0.6558392059574041 0.96004918573784 0.3370304608929317 1.0 0.8535978496352544 3 Q16850 1
Hur elavl1 binds and stabilizes mrna 0.5759334855262519 0.9504403487564872 0.3418885502391307 1.0 0.861977462512435 5 P35658 1
E2f mediated regulation of dna replication 0.4584908930070859 0.9503769650218238 0.3419207441592087 1.0 0.861977462512435 11 Q9UBD5,Q9Y619,P14635,P06493 4
Apoptotic cleavage of cell adhesion proteins 0.5341908689717143 0.94839068063317 0.3429306019923572 1.0 0.861977462512435 6 P42574,Q07157,Q14126,P35222 4
Golgi to er retrograde transport 0.282811751258014 0.9430826903904556 0.3456386087825156 1.0 0.8634158627052081 73 Q9Y496,P24390,Q15363,Q9P2W9,Q9Y3B3 5
Metabolism of steroid hormones 0.5315799852635433 0.936183860182084 0.3491785316262596 1.0 0.8634158627052081 6 Q14849,P30536,Q53GQ0 3
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.723448687350838 0.9351432453093008 0.349714482520167 1.0 0.8634158627052081 2 Q00534 1
Er quality control compartment erqc 0.7124105011933232 0.8917725392956628 0.3725148634280426 1.0 0.9036573475828608 2 Q9UBV2 1
Regulation of runx1 expression and activity 0.6371516646934646 0.8871117456762346 0.3750187409375218 1.0 0.9047270302260648 3 Q9HCE1 1
Copi mediated anterograde transport 0.2968779266669321 0.8844614413699984 0.3764471683186348 1.0 0.9047270302260648 57 P24390,O14653,P49755,Q9Y3B3,O14579,O75935,O95249,P61923,Q9Y678,Q13813,Q14746,Q14203,Q96JB2,Q13190,Q14204,Q9H0U4,Q14789,Q92538,Q9UJW0,O43237,Q15363,Q01082 22
Synthesis of pips at the golgi membrane 0.469384724630213 0.878657612746044 0.3795869477167 1.0 0.9059534658686595 9 Q08AM6,Q10713,Q9BTU6,P42356,O00443 5
Selective autophagy 0.3154894958279836 0.8708217029419604 0.3838515132235329 1.0 0.9102420536728936 38 P21796,Q9NS69 2
Cell surface interactions at the vascular wall 0.3822600833727794 0.8649101843520248 0.3870880873141078 1.0 0.9122176158599172 18 P78310,P53985 2
Beta oxidation of pristanoyl coa 0.5558926442850735 0.8632141798384549 0.3880197188300753 1.0 0.9122176158599172 5 O15254 1
Platelet calcium homeostasis 0.6002783328929617 0.8488700228394498 0.3959536210556937 1.0 0.9222157430291495 4 Q14571,P16615 2
Activation of nima kinases nek9 nek6 nek7 0.5522467777805586 0.8474737710293582 0.3967311007196008 1.0 0.9222157430291495 5 P14635,P53350,P06493 3
P75ntr regulates axonogenesis 0.6267393258152519 0.8468666370229913 0.3970694604094253 1.0 0.9222157430291495 3 Q9NQC3 1
Pre notch expression and processing 0.4581419928023325 0.8201807049984563 0.4121130998146509 1.0 0.9305391798297878 9 Q9UBV2,Q15363,P16615 3
Mitotic telophase cytokinesis 0.409092367062603 0.8154679893375743 0.4148044804917306 1.0 0.9305391798297878 13 Q7Z5K2,Q29RF7,Q9Y6X3,Q9NTI5 4
Purine salvage 0.4797042702718964 0.8089465551832123 0.4185458885689725 1.0 0.9305391798297878 7 P00813 1
Asparagine n linked glycosylation 0.318259683955446 0.7930153352954878 0.4277688881476167 1.0 0.9305391798297878 123 P24390,O60762,O95487,P04844,O14653,P49755,P04843,Q9Y3B3,P16278,O14579,O95249,Q9HCU5,P61923,O15084,Q9Y678,P61803,Q86YN1,O75352,Q9NYU2,Q9BV10,Q13813,P26572,Q14746,P10619,Q9Y6B6,P49257,Q14203,Q9UBV2,Q9Y223,Q96JB2,Q13190,Q14204,Q9H0U4,Q14789,Q92538,Q9BT22,Q9BUN8,Q12907,P46977,Q13724,O43237,Q15363,P27824,Q01082,Q2TAA5 45
Ros and rns production in phagocytes 0.4468445913908796 0.7901943016639009 0.4294143033960931 1.0 0.9305391798297878 10 Q9Y487 1
Vxpx cargo targeting to cilium 0.4534957288786373 0.7732844638338876 0.4393540482873739 1.0 0.9305391798297878 8 Q8TAG9,Q9UPT5,Q96A65,Q96KP1 4
Ngf stimulated transcription 0.6052266595388283 0.7648297239216755 0.4443729455669238 1.0 0.9324263582026676 3 Q14839 1
Triglyceride metabolism 0.4703528955852182 0.7640258299149237 0.4448518500417109 1.0 0.9324263582026676 7 Q9HCL2,Q8WTS1 2
Biological oxidations 0.2943971140746599 0.7563462037012024 0.4494416530054987 1.0 0.9338174853178524 45 P78417,Q9NUJ1,Q8TB61,Q16850,P21964,P16435,Q86WA6,Q99707,O43169,P07099,O00170 11
Energy dependent regulation of mtor by lkb1 ampk 0.4431116130463698 0.7429972472249253 0.4574833470463493 1.0 0.9425107676398908 9 Q15382 1
Diseases associated with glycosylation precursor biosynthesis 0.4471165430653255 0.7415300094451767 0.4583721431111986 1.0 0.9425107676398908 8 P10619,Q9Y223,P16278 3
Sumoylation of dna methylation proteins 0.5974180581328477 0.7354861259583897 0.462043486492826 1.0 0.9427488656220062 3 O00257 1
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.5702245880758744 0.730423386148404 0.4651314277748577 1.0 0.9427488656220062 4 P61586,P62942 2
Signaling by ptk6 0.4183062829819117 0.7253830488034043 0.4682170693941176 1.0 0.9427488656220062 11 P23246,P61586,Q14185 3
Hdr through homologous recombination hrr 0.3325286825758309 0.7247027487270818 0.4686344084709288 1.0 0.9427488656220062 25 Q07864,P35244,P35251,Q92547,Q13535,O60921,Q9NR33,P41440,Q9Y2S7,Q9UQ84 10
Unwinding of dna 0.439014159742137 0.7221914047030028 0.4701768071111805 1.0 0.9428862256591544 9 Q14566,P25205,P33991 3
Epha mediated growth cone collapse 0.4427347266167032 0.7198595056675023 0.4716115026481926 1.0 0.9428862256591544 8 P61586,P35580,O75116,P35579 4
Nostrin mediated enos trafficking 0.6673627684964243 0.7195095885668729 0.4718269964166168 1.0 0.9428862256591544 2 P50570 1
Synthesis of pips at the early endosome membrane 0.484142159849414 0.7184804889186418 0.4724610739657435 1.0 0.9428862256591544 6 O00443,Q08AM6 2
Condensation of prophase chromosomes 0.3994412449185346 0.7157326366093902 0.4741564544861503 1.0 0.9428862256591544 12 P14635,Q01105,Q9NTJ3,P42695,Q9UPP1,P06493 6
Rho gtpases activate rhotekin and rhophilins 0.6655727923627726 0.7128561613492939 0.47593476881773 1.0 0.9450704695094924 2 P61586 1
Runx3 regulates p14 arf 0.6646778042959471 0.7095358123680308 0.4779920359078184 1.0 0.94594452284899 2 P42771 1
Rhobtb3 atpase cycle 0.5899731423455674 0.7077555373090058 0.4790970820760352 1.0 0.94594452284899 3 P51151,O60664 2
Chondroitin sulfate dermatan sulfate metabolism 0.5164305935060137 0.6956791381181634 0.4866297931975787 1.0 0.9466398254941104 5 Q8NCH0 1
Diseases associated with glycosaminoglycan metabolism 0.5164305935060137 0.6956791381181634 0.4866297931975787 1.0 0.9466398254941104 5 Q8NCH0 1
Metabolism of vitamins and cofactors 0.282450588191918 0.6922131822910665 0.4888034614902827 1.0 0.9466398254941104 51 P00374,P78417,Q8N0U8,Q9H2D1,Q9HC21,P29375,Q99707,P43490,P11166,Q9Y5Z9 10
Mastl facilitates mitotic progression 0.5139592310426573 0.6854342265804652 0.4930699522717525 1.0 0.9466398254941104 5 P06493 1
Maturation of sars cov 2 nucleoprotein 0.4748352274068013 0.6770207207561761 0.4983928076366886 1.0 0.9492188488889192 6 P78362 1
Fatty acid metabolism 0.2757774434389292 0.6757592519166847 0.4991935097394244 1.0 0.9492188488889192 61 Q9BY49,P23786,O43772,P49748,O43808,P51648,O95864,Q9P035,O15254,P50897,Q6Y1H2,Q15067,Q53GQ0 13
Cardiac conduction 0.3920619532646134 0.6735243922301875 0.5006137359837681 1.0 0.9497570891473563 12 Q13555,Q99996,P16615 3
Activation of smo 0.5797974314565135 0.6702786697493246 0.5026801619788457 1.0 0.9517499223711956 3 Q9Y496 1
Response to elevated platelet cytosolic ca2 0.3062564301884307 0.6523279577792394 0.5141896280634626 1.0 0.959434356689028 31 Q9NZJ7,Q8NBX0,O43852,Q6UXV4,Q92520,Q9Y6I9,Q08380,P07602,O94919 9
Sulfur amino acid metabolism 0.4033220565014934 0.644340128631738 0.5193548993085229 1.0 0.9612560719558544 11 Q13126 1
Cohesin loading onto chromatin 0.4161652121495025 0.6311415143731883 0.5279479988902225 1.0 0.9719837330561713 10 Q7Z5K2,Q9Y6X3,Q9NTI5 3
Rhog gtpase cycle 0.2911621884371934 0.6229471071177307 0.5333192805227327 1.0 0.9774860337520598 36 P02786,Q86XL3,Q14739,P49257,P50402,O95202,Q14185,Q7L576,O15173,Q13190 10
Notch3 activation and transmission of signal to the nucleus 0.5648120763373049 0.6160858718793437 0.5378378460747113 1.0 0.9774860337520598 3 P67809 1
Transcriptional regulation of white adipocyte differentiation 0.3713587727515283 0.5930974562574949 0.5531159327303432 1.0 0.9882148412534408 13 P11802,Q9Y2X0,O60244,O75448,Q96EK7,Q14966,Q86X55 7
Intraflagellar transport 0.3636524820189382 0.5890327121178068 0.5558393298206914 1.0 0.98935247721329 14 Q9Y496 1
Rhou gtpase cycle 0.3419203283097245 0.5889779484504863 0.5558760663635063 1.0 0.98935247721329 18 P46940,P60953,Q9NZM3,Q00610,Q13813,Q03001,Q01082,Q9NNW5,Q93008 9
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.6312649164677857 0.588960197048131 0.5558879746068917 1.0 0.98935247721329 2 O00767 1
Interaction between l1 and ankyrins 0.529797924238872 0.5778225361817677 0.5633839385208061 1.0 0.9937863890151276 4 Q13813 1
Slc transporter disorders 0.2925218432032356 0.5716894227896065 0.5675324014833227 1.0 0.9944204231558118 33 Q92621,Q5SRE5,P35613,P53985,P11166,Q9BTX1,Q8NFH4,Q12769 8
Sema4d in semaphorin signaling 0.402955639691759 0.5651773238879431 0.5719531587890148 1.0 0.9950123788695 10 P08134,O75116,P35580,P35579,P61586 5
Cyclin a b1 b2 associated events during g2 m transition 0.3710221335974569 0.5564966147322925 0.5778714080213727 1.0 0.9990562899871992 12 P14635,P53350,P06493 3
G1 s specific transcription 0.3805466538793731 0.5256550122037509 0.5991279266930278 1.0 1.0 11 P00374,Q9Y619 2
Cellular response to chemical stress 0.245460803853648 0.5212083038376194 0.6022216701374461 1.0 1.0 76 P28070,P67870,Q5RI15,Q8TCT9,P00403,P30519,O75880,P09601,P28072,Q14997,P49721 11
Depolymerisation of the nuclear lamina 0.3914472177642216 0.509298821868372 0.6105427836080031 1.0 1.0 10 P14635,Q8NC56,P06493,P50402,P42167 5
Nef mediated downregulation of mhc class i complex cell surface expression 0.4695058929237459 0.5081792049005396 0.6113276730185409 1.0 1.0 5 P56377 1
Carnitine metabolism 0.4334984233021633 0.5005686016391835 0.6166747645370916 1.0 1.0 6 P23786 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3362929468036085 0.4941836285026307 0.6211765007668282 1.0 1.0 16 Q9BTY2,Q07065,Q02818 3
Downregulation of erbb2 erbb3 signaling 0.6020286396181442 0.4899027343493687 0.6242027280557014 1.0 1.0 2 P31751 1
Copii mediated vesicle transport 0.2815476628428739 0.4815605051060026 0.6301181883031228 1.0 1.0 33 Q9H0U4,O95487,Q12907,Q9Y6B6,O14653,P49257,Q15363,O15084,Q13190 9
Cytosolic iron sulfur cluster assembly 0.3903896824920635 0.4732782655140098 0.6360146662816935 1.0 1.0 8 Q96T76,P18074,O75027 3
P75 ntr receptor mediated signalling 0.3234458357899444 0.4717903268268044 0.6370764560828728 1.0 1.0 18 P61586,Q13501,Q9NQC3,Q14344 4
Sars cov infections 0.2550856464048167 0.4677490859351986 0.6399640341875625 1.0 1.0 63 O94973,P04844,O60341,O75116,P21964,Q14839,P48729,P46977,P62942,Q13330,Q13724,P26572,Q15185,P04843,Q99720,P78362 16
Flt3 signaling in disease 0.4238859577488283 0.4618009550174527 0.6442240659683454 1.0 1.0 6 Q92614,Q14789 2
Establishment of sister chromatid cohesion 0.3870201162759422 0.4584116801693039 0.6466567017363696 1.0 1.0 8 Q7Z5K2,Q9NTI5 2
Synthesis of pips at the er membrane 0.4926451785147022 0.4473890767369669 0.6545941612923656 1.0 1.0 4 P42356 1
Signaling by hippo 0.3974526917141864 0.4356957390338634 0.6630574976500414 1.0 1.0 7 P42574,Q07157,Q13043 3
Notch4 activation and transmission of signal to the nucleus 0.5844272076372381 0.4337900075033845 0.6644409385230396 1.0 1.0 2 Q92542 1
Insulin processing 0.381326851558764 0.4336401125200432 0.6645498014138329 1.0 1.0 8 Q96KP1,Q96A65,Q8TAG9 3
Signaling by erbb2 in cancer 0.4490892803821973 0.4324016733134672 0.6654495021655771 1.0 1.0 5 P62993,Q96RT1,P19174,P07900 4
Signaling by erbb2 ecd mutants 0.4490892803821973 0.4324016733134672 0.6654495021655771 1.0 1.0 5 P62993,Q96RT1,P19174,P07900 4
Rnd2 gtpase cycle 0.3168546401539273 0.4319348877928308 0.6657887374124192 1.0 1.0 18 Q07065,Q15058,P51648,Q03001,Q9ULH0 5
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.5832338902148033 0.4300920406780892 0.6671286896230888 1.0 1.0 2 P18887 1
Gpvi mediated activation cascade 0.4474263752048851 0.4264202625754917 0.6698016391763841 1.0 1.0 5 P61586,P60953 2
Potential therapeutics for sars 0.2648930285657268 0.4224920932939254 0.6726658706924398 1.0 1.0 40 O94973,O60341,O75116,P21964,P62942,Q13330,Q15185,Q99720 8
Netrin 1 signaling 0.3452451371639067 0.4218760135162513 0.6731155188528728 1.0 1.0 12 Q14185 1
Tp53 regulates metabolic genes 0.2629782510494383 0.4068096234800792 0.6841478180938037 1.0 1.0 40 Q5RI15,P42345,Q9HCE1,P00403,Q9Y6N1,O75880,Q15382 7
Post translational modification synthesis of gpi anchored proteins 0.4418398042991831 0.4065523466880662 0.6843368028676768 1.0 1.0 5 O60762,O43292 2
Plasma lipoprotein assembly remodeling and clearance 0.3183252791347208 0.3919304354680941 0.6951096141592932 1.0 1.0 16 O94973,Q6PIU2,Q8WTV0,O15118,Q9Y6B6 5
Rhobtb1 gtpase cycle 0.3013312532376314 0.3832423530708296 0.7015400776319338 1.0 1.0 20 Q9BT78,Q8IYB3 2
Tight junction interactions 0.4890807931933628 0.3669365434446353 0.7136663521199043 1.0 1.0 3 Q8NI35 1
Rhov gtpase cycle 0.3050962239485157 0.3638457855924432 0.715973170548077 1.0 1.0 18 P46940,P60953,Q00610,Q13813,Q96KM6,Q03001,Q01082,Q9NNW5,Q93008 9
Rac3 gtpase cycle 0.2639146060503142 0.3616908548372784 0.7175830618189869 1.0 1.0 34 Q14739,O15173,Q9Y2A7 3
Oncogene induced senescence 0.377450394040829 0.3558411038442138 0.721959564742289 1.0 1.0 7 Q9HCE1,Q00534,P42771 3
Rip mediated nfkb activation via zbp1 0.3773528533014614 0.3554662180766423 0.7222403486154438 1.0 1.0 7 Q13546,Q04206,Q9NZI8,O15111,Q08211,Q00653 6
Sars cov 2 infection 0.2881998356927399 0.3532227964422826 0.7239214189001659 1.0 1.0 23 P04844,P48729,P46977,Q13724,P26572,P27824,P04843,P78362 8
Transcriptional regulation by mecp2 0.3192461745552605 0.3473993707256441 0.72829130602751 1.0 1.0 14 Q9HCE1,P42858,Q14739 3
Glycogen breakdown glycogenolysis 0.3578865969238825 0.344877170306429 0.7301867143058551 1.0 1.0 9 P46020,P46976,P10253,P35573 4
Signaling by mapk mutants 0.5528042959427278 0.3408049596946323 0.7332504164617748 1.0 1.0 2 Q99956 1
Displacement of dna glycosylase by apex1 0.5525059665871193 0.3399800239088554 0.7338715714603579 1.0 1.0 2 P27695 1
Rrna processing in the mitochondrion 0.4219524806569031 0.3388676218296744 0.734709456852372 1.0 1.0 5 O15091 1
Complex i biogenesis 0.270951129832544 0.3382982918744732 0.7351384108056873 1.0 1.0 27 Q86Y39,Q9P0J0,Q9NPL8,O43676,Q8IUX1 5
Mismatch repair 0.3275617179144797 0.3368327273942377 0.7362430003472988 1.0 1.0 12 Q9UQ84,Q9Y2S7,P35244 3
Pexophagy 0.4773985987506536 0.3332379086866033 0.7389547048312657 1.0 1.0 3 Q13501 1
The citric acid tca cycle and respiratory electron transport 0.2514496830162509 0.3309951527201141 0.7406481469559285 1.0 1.0 96 P21796,O43676,Q8IUX1,Q86Y39,P00403,Q9Y6N1,Q9P0J0,O75964,Q9UDW1,Q13423,Q5RI15,O00330,P56134,P35613,O14949,Q8TB37,O75880,P24539,P53985,Q9NPL8 20
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.3875214405155001 0.325423032123515 0.7448609262209895 1.0 1.0 6 P78310 1
Regulation of pten localization 0.5471360381861647 0.325308295747396 0.7449477529363091 1.0 1.0 2 P98170 1
Peroxisomal protein import 0.2813176501664951 0.3121374791535052 0.7549360441876147 1.0 1.0 23 Q9BY49,O14975,Q9UKG9,O15254,Q15067,O00116,O43933 7
Regulation of tp53 activity through phosphorylation 0.2524803719254247 0.3115948878354105 0.7553484198672353 1.0 1.0 37 P67870,Q92804,Q92547,Q13535,O60921,Q9UQ84,P35244 7
Constitutive signaling by overexpressed erbb2 0.4489552238806072 0.3108040712311251 0.7559495744758284 1.0 1.0 4 P62993,P07900,Q96RT1 3
Fceri mediated ca 2 mobilization 0.4105703194983667 0.3024605517675919 0.7623010011301228 1.0 1.0 5 P62993,Q08209,P19174,Q14571 4
Phosphorylation of the apc c 0.3315644301042567 0.2974766082078628 0.7661026640752207 1.0 1.0 11 P14635,P53350,Q9UJX5,Q9UJX4,P06493 5
Receptor mediated mitophagy 0.4437827205626381 0.2960877974786295 0.7671630326147953 1.0 1.0 4 P67870,P68400 2
Plasma lipoprotein clearance 0.3172167991437973 0.290414941615341 0.7714988142823138 1.0 1.0 12 O94973,Q6PIU2,O15118,Q8WTV0 4
Retrograde transport at the trans golgi network 0.30013714311301 0.283868409614563 0.7765112265102359 1.0 1.0 15 P20645,Q5VZE5,Q14746,Q5VIR6 4
Autophagy 0.2378980879861351 0.2789593646499855 0.780276009608166 1.0 1.0 56 P21796,Q9NS69 2
Rhoc gtpase cycle 0.2577324074163977 0.2763320805079958 0.7822930181125101 1.0 1.0 30 P02786,P28288,P46940,O75116,Q14739,P61586,P49257,P41440,O75955,Q13190 10
Clec7a dectin 1 induces nfat activation 0.4526090071360475 0.2669490973918236 0.7895083535787406 1.0 1.0 3 Q14571 1
Signaling by ctnnb1 phospho site mutants 0.3661740326574447 0.2544537161429857 0.799145056679269 1.0 1.0 6 P48729,P49841,P35222 3
Beta catenin phosphorylation cascade 0.3661740326574447 0.2544537161429857 0.799145056679269 1.0 1.0 6 P48729,P49841,P35222 3
Disassembly of the destruction complex and recruitment of axin to the membrane 0.3661740326574447 0.2544537161429857 0.799145056679269 1.0 1.0 6 P48729,P49841,P35222 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3945204393272739 0.2543033545205185 0.7992612084420709 1.0 1.0 5 P31751,O14654 2
Cargo trafficking to the periciliary membrane 0.2831548968025847 0.2488626667469176 0.8034670145120444 1.0 1.0 18 Q3SYG4,Q9UPT5,Q96KP1,Q10713,Q96A65,O43924,Q8TAG9 7
Pregnenolone biosynthesis 0.4237000026785397 0.2422494687450499 0.8085868658000461 1.0 1.0 4 P30536 1
O linked glycosylation 0.4155814705905718 0.2220470922359531 0.8242772239427298 1.0 1.0 4 O43505 1
O linked glycosylation of mucins 0.4155814705905718 0.2220470922359531 0.8242772239427298 1.0 1.0 4 O43505 1
G beta gamma signalling through pi3kgamma 0.381949116671569 0.21936965991396 0.8263621023090042 1.0 1.0 5 P63218,P31751,P61586 3
Regulation of tp53 activity 0.2288630948476482 0.2154968435965631 0.8293799727040567 1.0 1.0 59 P67870,P42345,Q92804,Q14839,Q8TBX8,Q9UER7,P35244,Q92547,Q13535,O60921,P42771,Q9UQ84,P06493 13
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.2847101535701226 0.2146958710759302 0.8300044419238217 1.0 1.0 15 P09601 1
Regulation of pten gene transcription 0.2599573260529008 0.2120396320105407 0.8320761153625387 1.0 1.0 24 P42345,O60341,Q14839,O00257,Q13330,Q15382 6
Diseases of immune system 0.3771275007464875 0.2066532069042058 0.8362807039471389 1.0 1.0 5 Q04206,O15111,P09429,Q00653 4
Dag and ip3 signaling 0.3212591104063351 0.2054374228089365 0.837230384574192 1.0 1.0 8 Q13555 1
Homologous dna pairing and strand exchange 0.2769523447116058 0.203957263801266 0.8383868954171783 1.0 1.0 17 O60921,Q9UQ84,P35244,Q13535 4
Hdr through single strand annealing ssa 0.2769523447116058 0.203957263801266 0.8383868954171783 1.0 1.0 17 O60921,Q9UQ84,P35244,Q13535 4
The phototransduction cascade 0.4010292379125059 0.1882013411533952 0.8507188211865879 1.0 1.0 4 P53582 1
Ion homeostasis 0.3029349997703506 0.1881362041736097 0.8507698809785529 1.0 1.0 11 Q13555,P16615 2
Abc family proteins mediated transport 0.2252310060686917 0.1858611502485452 0.8525536489093157 1.0 1.0 50 P28070,P28288,O75027,Q8NE71,P56589,Q9UBV2,Q9BUN8,P08183,P28072,Q15008,Q14997,P49721,O00231 13
P38mapk events 0.4865751789976209 0.1849493622646768 0.8532687533111614 1.0 1.0 2 P11233 1
Mitotic g1 phase and g1 s transition 0.2119650235755765 0.1787506544771698 0.8581334931371862 1.0 1.0 76 P00374,P28070,P14635,P25205,Q07864,Q9UBD5,P35244,O43913,Q00534,P28072,Q9NR33,Q14566,Q15008,P33991,P42771,Q9Y619,P49721,P06493 18
Collagen formation 0.2850469826009977 0.1780102157198848 0.8587149528925047 1.0 1.0 13 Q03001,P13674,Q32P28,P50454 4
Srp dependent cotranslational protein targeting to membrane 0.2306978914384649 0.1748762312742646 0.8611768871539061 1.0 1.0 93 P04844,P60059,P42766,P04843,P27635,P62854,P62917,Q15629,P43307,Q9Y5M8,Q02543,P67812,P62910,P62273,P62847,P62753,Q9Y3U8,P46776,P51571,P61313,P39023 21
Peptide hormone metabolism 0.2839291183406682 0.1739460481586767 0.8619078630276995 1.0 1.0 13 Q9UPT5,Q96KP1,Q96A65,P67812,Q8TAG9 5
Nuclear envelope ne reassembly 0.2230507954465883 0.1710361757171021 0.8641953205737902 1.0 1.0 51 P14635,Q92621,Q86XL3,Q8IXJ6,Q14739,Q5SRE5,Q92973,P50402,O95067,Q9BTX1,Q8NFH4,Q12769,P06493,Q8N1F7 14
Formation of senescence associated heterochromatin foci sahf 0.3083147114414561 0.1658901752409394 0.8682433793873672 1.0 1.0 8 P16402,Q96L91 2
Disorders of transmembrane transporters 0.213372959307438 0.1656761865752418 0.8684117873969555 1.0 1.0 73 Q9BUN8,Q9UBV2,P35613,P53985,P28072,Q14997,P11166,Q9BTX1,P49721,Q12769 10
Uptake and function of diphtheria toxin 0.3892537313432924 0.1631048085955854 0.8704359137877538 1.0 1.0 4 P07900,Q16881,P08238 3
Regulation of hmox1 expression and activity 0.2241189711028714 0.1627619198189911 0.870705891964831 1.0 1.0 45 P28070,Q8TCT9,P09601,P28072,Q14997,P49721 6
Ca2 pathway 0.3057224507878857 0.1599369502219381 0.8729307410931848 1.0 1.0 9 P63218,Q9HCE1,Q08209,P35222,Q9UBI6,Q14571 6
Mrna decay by 3 to 5 exoribonuclease 0.2708651137887492 0.1596883874202654 0.8731265490050018 1.0 1.0 15 Q6PGP7,Q9NQT5,Q969T7,Q9GZS3,Q13868 5
Fanconi anemia pathway 0.3168595354848455 0.156192747405604 0.8758810933071361 1.0 1.0 7 Q9BXW9,P35244,Q13535 3
Sensing of dna double strand breaks 0.3550313526425813 0.1534329150601148 0.8780568897208423 1.0 1.0 5 P52292,Q13315,Q92878,P49959 4
Ub specific processing proteases 0.2084153430069721 0.1511059540266916 0.8798921357996177 1.0 1.0 76 P21796,Q9Y3E5,P28072,Q70CQ2,Q9Y4A5,Q14997,P45880,P49721,Q9UPT9 9
Negative regulation of nmda receptor mediated neuronal transmission 0.3259683551096016 0.1430422794942667 0.8862567902958487 1.0 1.0 6 Q13555,Q14012 2
G alpha 12 13 signalling events 0.2783285727640159 0.142348808513479 0.8868044954010399 1.0 1.0 12 P63218,P08134,Q13464,O75116,Q14344,P61586,Q9UBI6 7
Ikba variant leads to eda id 0.3770149253731383 0.139242009577439 0.8892589129806434 1.0 1.0 4 Q00653,O15111,Q04206 3
Assembly of the hiv virion 0.4558472553699381 0.1325600535058246 0.8945413262186204 1.0 1.0 2 Q99816 1
Apc c cdc20 mediated degradation of cyclin b 0.2947668720215997 0.1317592472100009 0.8951747214619901 1.0 1.0 10 P14635,Q9UJX4,P06493,Q9UJX5 4
Nuclear envelope breakdown 0.2205177465937508 0.1309603219411095 0.8958066955133379 1.0 1.0 42 P14635,Q8NC56,Q92621,Q5SRE5,P53350,P50402,O95067,Q9BTX1,Q8NFH4,P49792,P35658,Q12769,P06493,Q8N1F7 14
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.370447761194032 0.1273792350691267 0.8986402503685176 1.0 1.0 4 Q9UIW2,O94887,Q9Y490 3
Nuclear pore complex npc disassembly 0.2286011173409266 0.126744648674774 0.8991425062437788 1.0 1.0 31 P14635,Q92621,Q5SRE5,O95067,Q9BTX1,Q8NFH4,P49792,P35658,Q12769,P06493,Q8N1F7 11
Maturation of sars cov 1 spike protein 0.3409908254652835 0.1240613043142424 0.9012667360893508 1.0 1.0 5 Q13724,P26572 2
Zbp1 dai mediated induction of type i ifns 0.2907949790794908 0.1186820355613763 0.9055272694892652 1.0 1.0 8 Q13546,Q04206,Q9Y6K9,Q9NZI8,O15111,Q08211,Q00653 7
Sumoylation of immune response proteins 0.3769024171888958 0.1147179356519693 0.9086686971906022 1.0 1.0 3 Q00653,Q04206 2
Long term potentiation 0.3613753500504234 0.1120734798063148 0.91076514497486 1.0 1.0 4 Q13555 1
Ras activation upon ca2 influx through nmda receptor 0.3613753500504234 0.1120734798063148 0.91076514497486 1.0 1.0 4 Q13555 1
Unblocking of nmda receptors glutamate binding and activation 0.3613753500504234 0.1120734798063148 0.91076514497486 1.0 1.0 4 Q13555 1
Ctla4 inhibitory signaling 0.3115292712066849 0.1108238954814256 0.9117559962158056 1.0 1.0 6 P07947,P30153,P30154,P31751,Q14738 5
Constitutive signaling by aberrant pi3k in cancer 0.3115292712066841 0.110823895481424 0.911755996215807 1.0 1.0 6 P63000,Q9NWH9,P84095,P62993,O43815 5
Signaling by egfr in cancer 0.3329352045386684 0.1087954406036357 0.9133647402244208 1.0 1.0 5 P62993,P07900,P19174,Q16543 4
Constitutive signaling by ligand responsive egfr cancer variants 0.3329352045386684 0.1087954406036357 0.9133647402244208 1.0 1.0 5 P62993,P07900,P19174,Q16543 4
Constitutive signaling by egfrviii 0.3329352045386684 0.1087954406036357 0.9133647402244208 1.0 1.0 5 P62993,P07900,P19174,Q16543 4
Dex h box helicases activate type i ifn and inflammatory cytokines production 0.3591044776119455 0.1084381936997061 0.913648105555027 1.0 1.0 4 Q00653,Q04206,Q08211 3
Atf4 activates genes in response to endoplasmic reticulum stress 0.2665451203343085 0.1067078844148232 0.9150207274661688 1.0 1.0 12 O95453 1
G protein beta gamma signalling 0.2854115500177152 0.1056794873400773 0.9158366559308112 1.0 1.0 8 P63218,P31751,P61586,P60953 4
Activation of rac1 downstream of nmdars 0.3703372127723072 0.1052907262630955 0.916145121442697 1.0 1.0 3 Q14155,Q14012 2
Rab geranylgeranylation 0.247710081276078 0.1035573987255907 0.9175205967154264 1.0 1.0 18 Q9H0U4,P61026,P61020,P61019,Q969Q5 5
Vegfr2 mediated cell proliferation 0.3555223880597081 0.1028624144008011 0.918072168380556 1.0 1.0 4 O43865,P19174,Q14571 3
Synthesis of pips at the plasma membrane 0.261821927733835 0.102208048322708 0.9185915395759126 1.0 1.0 13 Q8TBX8,O00443 2
Class b 2 secretin family receptors 0.3510686318076008 0.096199075212187 0.9233624652838104 1.0 1.0 4 Q9Y3E5,P63218 2
Sting mediated induction of host immune responses 0.2907080968030995 0.0937635044797805 0.9252970231274726 1.0 1.0 7 Q9UJV9,P12956,P13010,P19474,P78527,P49959 6
Ksrp khsrp binds and destabilizes mrna 0.2574934503930974 0.0901293833668828 0.928184399685814 1.0 1.0 13 O95453 1
Inactivation of cdc42 and rac1 0.3569083855565524 0.0878487325933766 0.9299969044483404 1.0 1.0 3 P63000,P60953 2
Smac xiap regulated apoptotic response 0.349746344374813 0.0795327249380359 0.9366089033083868 1.0 1.0 3 P42574,P98170 2
Activation of caspases through apoptosome mediated cleavage 0.349746344374813 0.0795327249380359 0.9366089033083868 1.0 1.0 3 P42574,P98170 2
Diseases of mismatch repair mmr 0.3485526708445232 0.078211806428407 0.9376595706158272 1.0 1.0 3 P52701,P20585 2
Interleukin 1 processing 0.4060262529833005 0.0740284710677345 0.9409877307737358 1.0 1.0 2 Q00653 1
Irf3 mediated induction of type i ifn 0.2906212664277139 0.0717211615921397 0.9428238150143178 1.0 1.0 6 Q9UJV9,P12956,P13010,P78527,P49959 5
Assembly of the orc complex at the origin of replication 0.2694284170327111 0.0697037469086888 0.9444294594363352 1.0 1.0 9 Q9UBD5,Q9Y619 2
Perk regulates gene expression 0.2460791285577513 0.0691508908623583 0.9448695128930042 1.0 1.0 14 O95453 1
N glycan trimming in the er and calnexin calreticulin cycle 0.2453393797527396 0.067298986684724 0.9463436835702216 1.0 1.0 14 Q9UBV2 1
Cilium assembly 0.2033093277255395 0.0641679737114147 0.9488364780975024 1.0 1.0 60 Q3SYG4,Q9Y496,Q96KP1,Q10713,Q9UIS9,Q92973,O94927,Q99996,A0AVF1,O43924,P06493,Q8TAG9 12
Platelet homeostasis 0.2495952981880167 0.0634254259097878 0.9494277410596864 1.0 1.0 12 P63218,Q9UBI6,P16615,Q14571 4
Acyl chain remodeling of cl 0.3291554759773237 0.059249906611181 0.9527530597041868 1.0 1.0 3 Q6UWP7,P55084 2
Translation of sars cov 1 structural proteins 0.2580824348854822 0.0506552135740673 0.9596002651911756 1.0 1.0 8 P27824,Q10472,Q13724,P26572 4
Irs mediated signalling 0.3113432835820951 0.0494182660768215 0.960585971721756 1.0 1.0 4 Q99570,P62993,P31751 3
Interactions of vpr with host cellular proteins 0.2045047166360261 0.0486890191411912 0.9611671269538083 1.0 1.0 34 P12235,P05141,Q92621,Q5SRE5,P17096,P12236,Q9BTX1,Q8NFH4,P49792,P35658,Q12769,Q8N1F7 12
Ticam1 rip1 mediated ikk complex recruitment 0.3029850746268661 0.0422716084753659 0.9662821782029396 1.0 1.0 4 O15111,Q9Y6K9,Q13546 3
Nade modulates death signalling 0.350238663484491 0.0405182789859322 0.9676799344839078 1.0 1.0 2 P42574 1
Rho gtpases activate cit 0.2355547936246847 0.0346244611004224 0.9723791960541142 1.0 1.0 12 P61586,P35580,Q15058,P35579 4
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.2429672304539303 0.0337205637366928 0.9730999808057548 1.0 1.0 11 P56377,Q9BXS5,O95782,O94973 4
Regulation of innate immune responses to cytosolic dna 0.290447761194033 0.0331088773197882 0.9735877635548876 1.0 1.0 4 P19474,Q9NZI8,Q9UJV9 3
Cd28 co stimulation 0.2427875001837631 0.0247152860574183 0.9802820622945356 1.0 1.0 9 P42345,P31751 2
Dna replication initiation 0.264929665215736 0.023715229376525 0.9810797581367006 1.0 1.0 5 Q07864 1
Ncam signaling for neurite out growth 0.2534531816562397 0.0232759192480769 0.9814301801655854 1.0 1.0 6 Q13813 1
Collagen biosynthesis and modifying enzymes 0.2363769529043516 0.0230905245142061 0.9815780640148848 1.0 1.0 11 P13674,Q32P28,P50454 3
Dual incision in gg ner 0.2032906173745733 0.0154892958105574 0.987641824175748 1.0 1.0 24 Q07864,P35251,P19447,Q9NR33,P41440,P18074,Q9Y2S7,P35244 8
Darpp 32 events 0.2346786248131624 0.0143546831083762 0.988547013301834 1.0 1.0 9 P10644,Q08209,P30153,P30154,P62136,Q00535,P17612,Q14738 8
Rnd3 gtpase cycle 0.2129401735511645 0.0118892020118771 0.9905140127539728 1.0 1.0 17 Q07065 1
Fcgr3a mediated il10 synthesis 0.2345383925903724 0.0105310435623773 0.9915975982411472 1.0 1.0 7 P07947,P10644,P17612,P19174,Q14571,O43865 6
Rho gtpases activate ktn1 0.2281799784997791 0.0104264409396295 0.9916810544767776 1.0 1.0 8 P61586,P60953 2
Resolution of sister chromatid cohesion 0.186307804178242 0.003701994438279 0.9970462425402782 1.0 1.0 66 Q7Z5K2,Q9H900,Q6P1K2,P50748,P14635,Q92674,Q29RF7,Q9NTI5,P53350,P49454,Q9BZD4,Q9BS16,Q8NFH4,Q12769,P06493 15
Triglyceride catabolism 0.2239586108535143 0.0012634189569555 0.9989919377886024 1.0 1.0 6 Q8WTS1 1
Interleukin 4 and interleukin 13 signaling 0.213370692222624 0.0012510699325023 0.9990017908767672 1.0 1.0 12 P09601 1