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6334d13 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Transport of small molecules 0.4507490549712922 3.606748092802897 0.0003100584029676 0.350172287297644 0.2239152389970024 153 P35611,P56589,P28070,P30519,O15439,O00231,Q8WTV0,Q15008,Q70HW3,P11166,Q8N4V1,P21796,Q9H300,Q9UBV2,P45880,Q9NW15,P49721,Q13546,Q9Y487,O95202,Q93050,Q14997,P51790,P28072,Q9Y666,Q9UPY5,Q9HD20,Q9Y5K8,Q8WWC4,Q8IYU8,Q10713,P08183,Q9C0H2,P20618,P09601,Q9BUN8,Q6PIU2,O15118,Q9NWR8,O75027,Q8TB61,Q9UBX3,P53985,O43242,P40855,P25787,Q15904,Q9BPX6 48
Cholesterol biosynthesis 0.7734887640002741 3.4465976456991685 0.0005676933703668 0.545845509449725 0.2239152389970024 19 Q15125,Q9BWD1,Q15800,Q16850,Q9UBM7,Q15392,O75845,Q14739,P48449,Q14534 10
Intra golgi and retrograde golgi to er traffic 0.4754688400666777 3.380021292138367 0.0007248021458663 0.634993555461832 0.2239152389970024 92 Q9UID3,P24390,Q14203,O60333,Q8TBA6,Q8TD16,Q9Y496,O43237,O15498,Q9Y3B3,O95249,Q14746,Q9H0U4,Q96Q89,P20645,O15260,Q13190,Q9Y6G9,O00461,P49755,Q9UJW0,O14653,Q5VZE5,Q15363,P84085,Q9BUF5,P61923,O75935,Q9NRW7,Q9P2W9,Q96JB2 31
Mitochondrial calcium ion transport 0.7585750911836864 3.2751921622013005 0.0010559012284283 0.769724331245078 0.2239152389970024 18 O95202,Q9H300,P21796,Q8WWC4,Q8IYU8,Q10713,P45880,Q9BPX6 8
Sphingolipid metabolism 0.6758062144129511 3.2219780296285583 0.0012730889684318 0.829789785192365 0.2239152389970024 26 Q06136,P04062,Q96G23,P10619,P16278,P07602,Q13510,Q16739,Q9NZJ7,O95470 10
Protein localization 0.4804535345461642 3.1527103194175843 0.0016176224521673 0.894634053179831 0.2239152389970024 77 O60830,Q9NS69,Q99595,Q8N4H5,Q15067,Q9UJS0,P09601,Q9Y584,Q9NR77,Q13011,O15254,Q13505,P21796,Q9BY49,P46379,O43933 16
Glycosphingolipid metabolism 0.7593295000711532 3.0838925531663697 0.002043113699389 0.941739628317054 0.2239152389970024 15 P04062,P10619,P16278,P07602,Q13510,Q16739 6
Mitochondrial protein import 0.5591786354989813 2.920363277579378 0.0034962356989662 0.9923134476234914 0.2239152389970024 34 O60830,Q9NS69,Q99595,Q8N4H5,Q9UJS0,Q9Y584,Q13505,P21796 8
Ion channel transport 0.5854603549578915 2.752069325788577 0.0059219982912046 0.9997403167595984 0.2547880271596674 29 Q9Y487,Q93050,P51790,Q9C0H2,Q9HD20,Q9NW15,Q15904 7
Slc mediated transmembrane transport 0.6387302587346189 2.6982049632419725 0.0069714503149458 0.9999401848466124 0.2691754427159643 20 Q8TB61,Q9UBX3,P53985,Q9Y666,P11166,Q70HW3 6
Metabolism of steroids 0.4946170322244185 2.6858355453526817 0.0072348689020924 0.99995863282258 0.2717964263218519 50 Q15125,P30536,Q9BWD1,P04062,Q15800,Q16850,Q9UBM7,Q15392,O75845,Q53GQ0,Q14849,Q14739,P48449,Q9HCL2,Q14534,Q9BZF3 16
Processing of smdt1 0.6731644874146928 2.498197939245646 0.0124826472605201 0.9999999738673894 0.3500031279003122 13 Q9H300,Q8WWC4,Q8IYU8,Q10713,Q9BPX6 5
Iron uptake and transport 0.5908556030322827 2.3066474346775427 0.0210744828730404 0.9999999999998612 0.3891122111650123 19 P30519,Q9Y487,Q93050 3
Stimuli sensing channels 0.7503688813441272 2.2682226630939777 0.0233156388133746 0.9999999999999942 0.3891122111650123 9 P51790,Q9C0H2,Q9NW15 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.8395904073721413 2.2604474865467687 0.0237934921324747 0.9999999999999972 0.3891122111650123 6 Q9NR77,Q16850 2
Mitophagy 0.6246916078373198 2.2135623549206165 0.0268588993553944 1.0 0.394638417761005 13 O96008,Q13501,Q9NS69,P68400,Q8N4H5,P21796,P67870,Q8IWA4 8
Metabolism of lipids 0.3917429551217347 2.2053921700625456 0.027426587014278 1.0 0.394638417761005 200 Q96PE3,P42356,Q9NPH0,P20339,Q15067,O00116,P38435,Q9BWD1,P04035,P16278,P07602,Q9H4L5,Q16739,P50897,P49748,Q9NZC3,P30536,P27544,P04062,Q15800,Q6Y1H2,O15254,P35790,Q8NCC3,Q9NQZ5,Q15392,Q99570,O43772,Q10713,Q08AM6,Q8IV08,P48449,O95470,Q9Y2X0,Q06136,O14734,P06865,P09960,P23786,Q92604,Q96G23,Q5SGD2,Q16850,O75448,Q8TBX8,Q9BY49,P67870,Q53GQ0,Q9BTU6,Q14739,Q9HCL2,Q14849,Q14534,P68400,Q15125,Q9UG56,O00443,O95864,P37268,P10619,Q9NZ01,Q8WTS1,Q9UBM7,O75845,Q13510,Q9P035,Q86UL3,Q9NZJ7,Q9BZF3 69
Golgi to er retrograde transport 0.4055451584761174 2.1897093855222325 0.0285453199776608 1.0 0.394638417761005 73 P24390,Q14203,O60333,Q8TD16,Q9Y496,O43237,Q9Y3B3,Q9H0U4,Q96Q89,O15260,Q9Y6G9,P49755,Q9UJW0,Q15363,P84085,Q9BUF5,P61923,O75935,Q9P2W9 19
Metabolism of porphyrins 0.7120972732365336 2.187821199889454 0.0286826290134978 1.0 0.394638417761005 10 P30519,P09601,P22830 3
Peptide ligand binding receptors 0.8139402907983951 2.1508079709165435 0.0314913597010118 1.0 0.4168856188991086 6 P04083,P07602,P42892 3
Class a 1 rhodopsin like receptors 0.8139402907983951 2.1508079709165435 0.0314913597010118 1.0 0.4168856188991086 6 P04083,P07602,P42892 3
Signaling by insulin receptor 0.5856199151687876 2.143719997925571 0.0320553288660396 1.0 0.417778724993009 17 Q9Y487,P28482,Q93050,P31751,Q9Y5K8,Q15904 6
Synthesis of pips at the early endosome membrane 0.8095554613331853 2.1319342269956123 0.0330122540004604 1.0 0.4195845414879824 6 Q08AM6,Q96PE3,Q9BTU6,O00443 4
Heparan sulfate heparin hs gag metabolism 0.8511234066376487 2.1109114459378713 0.0347799240822603 1.0 0.4278238449056808 5 O94766,P54802,P16278 3
Apoptotic cleavage of cellular proteins 0.5603026800601499 2.101177704802488 0.035625369769523 1.0 0.4278715679761584 19 P35611,P02545,Q13464,P51572,P15924,Q15149,P08670,Q9UDY2 8
Phospholipid metabolism 0.4242098139533341 2.046301025468645 0.0407267628821754 1.0 0.4498963347796984 53 Q96PE3,P42356,Q9NPH0,P20339,Q9NZC3,P35790,Q8NCC3,Q9NQZ5,Q99570,Q08AM6,Q10713,Q8IV08,Q92604,Q8TBX8,P67870,Q9BTU6,Q9HCL2,P68400,Q9UG56,O00443,Q86UL3 21
Glycosaminoglycan metabolism 0.5901486066614893 2.0418565363086763 0.0411657642148239 1.0 0.4498963347796984 14 Q8TB61,Q8NCH0,P16278,O94766,P54802,Q7LGA3,O43505 7
Heme degradation 0.8905881418113956 1.9824907444604432 0.0474243422671567 1.0 0.492669351492412 4 P30519,P09601 2
Metabolism of fat soluble vitamins 0.8184487449688578 1.97544914918453 0.0482171998974112 1.0 0.492669351492412 5 Q9Y5Z9,Q6NUM9 2
Ire1alpha activates chaperones 0.5086302280248032 1.9621818393892283 0.0497413174921963 1.0 0.492669351492412 25 P43307,O14773,O95070,P49748 4
Intra golgi traffic 0.5824853587777507 1.9583861997362744 0.0501847128653711 1.0 0.492669351492412 13 Q13190,Q9NRW7,Q14746,O95249,O00461,Q8TBA6,Q96JB2,O15498 8
Synaptic adhesion like molecules 0.7513421645231602 1.9394331273016057 0.0524486200032212 1.0 0.492669351492412 7 O95197,P41440,Q92796 3
Rhoa gtpase cycle 0.435282197669858 1.9393652350688664 0.0524568805905589 1.0 0.492669351492412 44 Q13190,O75116,O15173,P30519,P14923,P51572,P46940,O75955,Q9UDY2,O15498,P41440,Q14739,Q15904,Q96HY6 14
Synthesis of pc 0.7601553166069204 1.916717230799989 0.0552738650122863 1.0 0.5073054168633289 6 P68400,P35790,P19784,Q9NQZ5,P67870 5
Transport of inorganic cations anions and amino acids oligopeptides 0.6700761205578122 1.8705148700676 0.0614123540029456 1.0 0.5169127208917472 9 Q9Y666,Q9UBX3,Q70HW3 3
Ras processing 0.8614284279977984 1.868110077415816 0.0617467291807805 1.0 0.5169127208917472 4 O43924 1
Copi mediated anterograde transport 0.395802822431215 1.8635770028907055 0.0623811296469312 1.0 0.5169127208917472 57 O15020,P24390,Q14203,O43237,O15498,Q9Y3B3,O95249,Q14746,Q9H0U4,Q13190,Q9Y6G9,P49755,Q9UJW0,O14653,Q15363,Q9BUF5,P61923,O75935,Q96JB2 19
Synthesis of pips at the golgi membrane 0.6686868211118767 1.8634906907773905 0.0623932610744386 1.0 0.5169127208917472 9 P42356,Q9BTU6,O00443,Q08AM6,Q10713 5
Phosphorylation of the apc c 0.6291674212599013 1.8631189521550249 0.0624455323613042 1.0 0.5169127208917472 11 Q9UJX2,P14635,P53350,Q96DE5,P06493,Q9UJX5,Q9UJX4,Q9H1A4 8
Rnd3 gtpase cycle 0.5421099545455418 1.8588083745273465 0.0630543050049763 1.0 0.5169127208917472 17 P15924,Q07065,O43396,P38159 4
Apoptotic cleavage of cell adhesion proteins 0.7470241816049452 1.8587375638729309 0.0630643462352886 1.0 0.5169127208917472 6 P15924 1
Ros and rns production in phagocytes 0.6458417902022764 1.8445956178320757 0.065096384948287 1.0 0.5243438094640024 10 Q9Y487 1
Cargo trafficking to the periciliary membrane 0.5301121410540223 1.8339451130068611 0.0666621420275472 1.0 0.5294878709616613 18 Q96KP1,Q9UPT5,O43924,Q3SYG4,Q10713 5
Copi dependent golgi to er retrograde traffic 0.4117840001806034 1.8258381598459097 0.0678746434129407 1.0 0.5346081735132804 50 Q9Y3B3,O15260,P24390,O60333,P61923,P49755,Q9H0U4,Q9P2W9,Q15363,Q9Y496,Q9BUF5,Q96Q89 12
Pink1 prkn mediated mitophagy 0.6539234984117165 1.788567139081893 0.0736845540043704 1.0 0.545753902565139 9 Q9NS69,P21796 2
Rnd1 gtpase cycle 0.5423721353050743 1.7783506622135534 0.0753462804715261 1.0 0.545753902565139 15 P15924,Q15058,P38159 3
Transferrin endocytosis and recycling 0.5830314311731726 1.7723769161349685 0.0763320110285605 1.0 0.545753902565139 12 Q9Y487,Q93050,P02786,Q9Y5K8,Q15904 5
Formation of the cornified envelope 0.7257157833234598 1.7640025252735374 0.0777315540345693 1.0 0.545753902565139 6 P14923,P15924,Q14574 3
Keratinization 0.7257157833234598 1.7640025252735374 0.0777315540345693 1.0 0.545753902565139 6 P14923,P15924,Q14574 3
Regulation of mecp2 expression and activity 0.6481224818815056 1.758989497334995 0.0785792924711756 1.0 0.545753902565139 9 Q14739,P42858 2
Condensation of prometaphase chromosomes 0.609902755930344 1.7569967094041252 0.0789183700831603 1.0 0.545753902565139 11 P68400,P14635,O95067,Q15021,P19784,P67870,P06493 7
Apc c cdc20 mediated degradation of cyclin b 0.6211339602674677 1.7136535500368526 0.0865923724701793 1.0 0.5674796975825934 10 Q9UJX2,P14635,Q96DE5,P06493,Q9UJX5,Q9UJX4,Q9H1A4 7
Hs gag degradation 0.9576372315035804 1.683945545592577 0.0921921930734372 1.0 0.5674796975825934 2 P54802 1
Gpcr ligand binding 0.6124222377799353 1.66713879903507 0.0954868087423896 1.0 0.5720976903100071 10 P04083,P07602,P42892 3
Insulin receptor recycling 0.589168919166914 1.6417030109313988 0.1006515673763597 1.0 0.5917416870758331 11 Q9Y487 1
E2f enabled inhibition of pre replication complex formation 0.6956989510337692 1.629287144884831 0.1032522462197129 1.0 0.5961155126939149 6 P14635,Q9UBD5,Q9Y619 3
Cytoprotection by hmox1 0.363079456416141 1.6242906472522585 0.1043137923908179 1.0 0.5962989745788196 66 P28070,P30519,O00231,Q15008,P15954,P49721,Q14997,P28072,P60900,Q9Y6N1,Q8TCT9,P20618,P13073,P09601,P00403,P67870,P68400,O43242,Q5RI15,O75880,P25787,P30043 22
Plasma lipoprotein clearance 0.55659588255955 1.616589207683894 0.1059669830514198 1.0 0.5962989745788196 12 Q8WTV0 1
Synthesis of pips at the late endosome membrane 0.792746574281866 1.5945981748624811 0.1108021210124872 1.0 0.5962989745788196 4 Q08AM6,O00443 2
Miscellaneous transport and binding events 0.6870952534000531 1.5904265823692798 0.111738682388963 1.0 0.5962989745788196 6 P35611,Q8N4V1,Q8IWT6 3
Synthesis of pe 0.931682577565633 1.5811549165530745 0.1138426207227671 1.0 0.5962989745788196 2 P35790 1
Glycerophospholipid biosynthesis 0.427027711211853 1.5659291723124449 0.11736519945917 1.0 0.5962989745788196 31 Q9NPH0,P35790,Q8NCC3,Q9NQZ5,Q8IV08,Q9HCL2 6
Striated muscle contraction 0.7774306299940176 1.532956530279549 0.1252865658117998 1.0 0.6067885940014001 4 P08670,P67936 2
Synthesis of pips at the plasma membrane 0.5136707888574242 1.528879695974209 0.1262942705668885 1.0 0.6079102782873803 13 Q96PE3,P20339,O00443,Q8TBX8,Q9BTU6 5
Diseases of glycosylation 0.4672005125693657 1.5284822130969415 0.1263928564209013 1.0 0.6079102782873803 21 P06865,Q8NCH0,O75340,Q2TAA5,Q9BT22,Q9BV10,P10619,P16278,O94766,O60762,O43505 11
Phase i functionalization of compounds 0.508411866276053 1.5250517828905397 0.127246182308937 1.0 0.6089131641787908 14 P07099,O43169,Q16850 3
Glycogen breakdown glycogenolysis 0.6015815166113352 1.5191446184751622 0.1287260978474 1.0 0.6107299674691493 9 P11216,P46976,P10253,P46020 4
Nr1h2 and nr1h3 mediated signaling 0.6959680751410097 1.45337001846051 0.1461210461891404 1.0 0.6655791118423855 5 Q8NB78 1
Small interfering rna sirna biogenesis 0.6956340755637471 1.451922443112806 0.1465231713840071 1.0 0.6655791118423855 5 O75569 1
Sphingolipid de novo biosynthesis 0.5532468146776519 1.4396677792238095 0.1499614134321634 1.0 0.6745837044359454 11 Q06136,Q96G23,O95470 3
Diseases of carbohydrate metabolism 0.6102522902470306 1.4167489198372605 0.1565563487884871 1.0 0.6864926152765991 8 P46976,P54802,P16278 3
Nephrin family interactions 0.6097655873238245 1.4143458646877662 0.157260376603082 1.0 0.6864926152765991 8 P12814,O43707,P46940,Q9Y5K6 4
Metabolism of folate and pterines 0.579441362695032 1.403711544556655 0.1604047633064536 1.0 0.6945876043488177 9 P00374,Q9H2D1 2
Cargo concentration in the er 0.4830814478627114 1.3911381519270871 0.164183537634849 1.0 0.70436764602605 15 Q13190,P49755,P49257,O14653,Q9Y6B6,Q15363,Q96PC5 7
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5180719915268779 1.386521363870054 0.1655877613885323 1.0 0.7082061179386462 12 P09601,Q13190,P46379,P50402 4
Plasma lipoprotein assembly remodeling and clearance 0.476677543853462 1.3814976332952271 0.1671260050162495 1.0 0.7104132934941494 16 Q8WTV0 1
Cdc6 association with the orc origin complex 0.677951333618944 1.3751769532911322 0.1690765915153367 1.0 0.7114915698387699 5 Q9UBD5 1
Chondroitin sulfate dermatan sulfate metabolism 0.6722656884248519 1.3504635590777152 0.1768673351026142 1.0 0.7188467713234905 5 O94766,Q8NCH0 2
Diseases associated with glycosaminoglycan metabolism 0.6722656884248519 1.3504635590777152 0.1768673351026142 1.0 0.7188467713234905 5 O94766,Q8NCH0 2
Pi metabolism 0.4358356837802049 1.3393876494355226 0.1804445079765331 1.0 0.7295732220117257 23 Q96PE3,P42356,Q9NZC3,P20339,Q9BTU6,O00443,Q99570,Q08AM6,Q10713 9
Initiation of nuclear envelope ne reformation 0.4582798962637856 1.3370544394283417 0.1812048674620947 1.0 0.7295732220117257 18 P02545,P14635,O95067,P63151,Q86XL3,P50402,Q8IXJ6,Q14739 8
Interleukin 4 and interleukin 13 signaling 0.5081149590020816 1.3266194671017946 0.1846345929027797 1.0 0.7295732220117257 12 P09601,P04083 2
Synthesis of very long chain fatty acyl coas 0.5919819708345184 1.326385259311556 0.1847121188825551 1.0 0.7295732220117257 8 Q53GQ0,Q6Y1H2,Q9NZ01 3
Signaling by hippo 0.6184141770044536 1.326255041430178 0.1847552332000916 1.0 0.7295732220117257 7 Q13043,Q9UDY2 2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5868957193819372 1.3011821041953713 0.1931961293478388 1.0 0.7382399734744012 8 Q9UJX2,Q96DE5,Q9UJX5,Q9UJX4,Q9H1A4 5
Signaling by vegf 0.3967536073545671 1.2985506752873843 0.1940981747189782 1.0 0.7382399734744012 31 P04792,Q14571,Q9UQB8,O75116,Q14185,Q13464,P42345,P14923,P31751,Q96F07 10
Glycogen metabolism 0.503078265503377 1.2962722950911665 0.1948816899829661 1.0 0.7382399734744012 12 P11216,P46976,P10253,P46020 4
Keratan sulfate keratin metabolism 0.6564016445012208 1.2814503968465276 0.2000355121775292 1.0 0.7523417564241416 5 P06865,O43505,P16278 3
Cilium assembly 0.3379464283195577 1.276565263266735 0.2017557720962854 1.0 0.7523417564241416 60 Q14203,P41208,O43924,Q96A65,Q7Z460,Q9Y496,Q3SYG4,Q8TAG9,Q96KP1,P53350,A0AVF1,O94927,Q10713,P17612,Q7Z4H7,Q9BUF5,Q9UPT5,O75935,Q15019,P06493 20
Smooth muscle contraction 0.4981918324089132 1.266807287389829 0.2052242057443503 1.0 0.7563072209635885 12 P04083,P07355,P67936 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.648609635518401 1.2475383673468472 0.2122001612324346 1.0 0.763905711502331 5 P31751,O14654 2
Signaling by mapk mutants 0.8460620525059661 1.241737966139957 0.2143332571841072 1.0 0.763905711502331 2 Q99956 1
Neutrophil degranulation 0.3158935039958788 1.2276980096615695 0.2195603538824821 1.0 0.7753586991593019 166 P42785,P61026,P28482,P31949,Q9BXS5,P30519,P11216,P61020,O00560,O00231,Q15008,P16278,Q8WVQ1,P07602,Q07065,Q7L576,Q93050,Q13464,Q969Q5,P15924,Q9Y5K8,P10321,P46940,P20618,O15260,O00264,Q9Y6G9,O00584,P09960,O43681,P06737,P67870,P10253,P07355,P07384,P46976,Q9BTY2,O43242,Q5T9A4,P14923,P17931,P10619,Q9Y376,Q13510,P25787,Q9NZJ7 46
Receptor mediated mitophagy 0.699014725296063 1.2154876189718549 0.224180168086284 1.0 0.7767075191611106 4 P68400,P67870 2
Class i peroxisomal membrane protein import 0.5287267489915812 1.213396740117069 0.2249781720714514 1.0 0.7767075191611106 10 Q9NR77,P28288,P40855,P56589 4
Ncam signaling for neurite out growth 0.6035509889459847 1.2092286235091074 0.2265750238620911 1.0 0.7767075191611106 6 O15020,P28482,P62993 3
Calcineurin activates nfat 0.836813842482103 1.2052803087378152 0.22809510865667 1.0 0.7789980369355562 2 P62942 1
Insulin receptor signalling cascade 0.6005505756505303 1.1954782750644024 0.2319002193105794 1.0 0.7852604847293742 6 P31751,P28482 2
Insulin processing 0.56244103211777 1.179865062895831 0.2380538872100444 1.0 0.795420440437408 8 Q96KP1,Q9UPT5,Q8TAG9 3
Recruitment of mitotic centrosome proteins and complexes 0.3710769369694854 1.1657098128361876 0.2437317913698349 1.0 0.8028873333049201 33 Q14203,P17612,P41208,Q7Z4H7,O75935,P53350,O94927,Q7Z460,Q96CW5,P06493,Q9BSJ2 11
Wax and plasmalogen biosynthesis 0.6865671641791087 1.1650814482935463 0.2439860255077779 1.0 0.8028873333049201 4 O15228,Q6IAN0,O00116 3
Cd28 dependent pi3k akt signaling 0.8263723150358013 1.1642273218141612 0.2443319007107778 1.0 0.8028873333049201 2 P31751 1
G2 m dna replication checkpoint 0.6845838792369299 1.1570576060305275 0.2472488255976039 1.0 0.8048977323259136 4 P14635,O95067 2
Mapk family signaling cascades 0.3197256817274375 1.1570303742234966 0.2472599508655864 1.0 0.8048977323259136 87 O15020,P28482,O43924,P28070,O00231,Q15008,O60725,P31946,P51665,P49721,Q14997,P28072,P60900,Q99956,P46940,P20618,P04792,P17612,Q9HCE1,Q92796,Q16181,P21359,Q9Y4G8,O43242,P06493,P25787 26
Diseases of mitotic cell cycle 0.4797175401196303 1.1552960709355444 0.2479692043876138 1.0 0.8053205469597738 12 Q9UJX2,Q9UER7,Q00534,P11802,Q16763,Q96DE5,Q9UJX5,Q9UJX4,Q9H1A4 9
Visual phototransduction 0.5812116141389053 1.151394006821148 0.249570178302261 1.0 0.806750111256146 7 P53582 1
Synthesis of pa 0.516583026984756 1.1470180803873808 0.2513741484822478 1.0 0.8090894079167626 10 Q9NPH0 1
Mucopolysaccharidoses 0.8351600868190421 1.1426910688976943 0.2531668792174586 1.0 0.8090894079167626 3 P54802 1
Protein protein interactions at synapses 0.4485160940213892 1.135629558112942 0.2561116329067983 1.0 0.8090894079167626 14 O95197,P41440,Q92796 3
Estrogen dependent nuclear events downstream of esr membrane signaling 0.6786189660268548 1.1329409241616786 0.2572390626397736 1.0 0.8090894079167626 4 P31751 1
Peroxisomal protein import 0.4083613065682413 1.1286451438937224 0.2590475587590513 1.0 0.8090894079167626 23 O14734,Q15067,P50542,O00116,P14735,O15254,Q13011,Q9BY49,O43933 9
Rhobtb1 gtpase cycle 0.4142888031213104 1.1196191412756995 0.2628760951884814 1.0 0.8122660955441927 20 O75116,P61201,O43396,Q13464,Q8N684,P38159,P08670,Q9BT78 8
Rhov gtpase cycle 0.4269915947778527 1.117634461262904 0.2637231443253909 1.0 0.8122660955441927 18 Q96KM6,O43396,P06753,Q13813,P46940,Q14155,P67936 7
Vxpx cargo targeting to cilium 0.5497665293548941 1.1169959193483374 0.2639960699588095 1.0 0.8122660955441927 8 Q96KP1,Q9UPT5,Q8TAG9 3
Oncogene induced senescence 0.573435009142169 1.1148610900283424 0.2649099528713612 1.0 0.8128583542851923 7 Q9HCE1,P11802,P28482 3
Epha mediated growth cone collapse 0.5453821701961715 1.0952670872308696 0.273399642181146 1.0 0.8225660230125388 8 O75116,Q7Z406,P35579 3
Sulfide oxidation to sulfate 0.8042959427207672 1.0779157754719406 0.2810713446367621 1.0 0.8348059167630327 2 Q9UBX3 1
Glycogen storage diseases 0.8166985311802379 1.0759086534260442 0.2819681114563643 1.0 0.8348214329244091 3 P46976 1
Synthesis of pips at the er membrane 0.6616048055946238 1.064318871988005 0.2871842715996502 1.0 0.837285428130992 4 P42356 1
Activation of gene expression by srebf srebp 0.4064077589497317 1.061824489076089 0.2883153701747796 1.0 0.837285428130992 20 Q16850,Q9UBM7,O75845,P48449,Q9HCL2,Q14534 6
Tlr3 mediated ticam1 dependent programmed cell death 0.8001193317422441 1.0616762480036592 0.2883826857433824 1.0 0.837285428130992 2 Q13546 1
Trif mediated programmed cell death 0.8001193317422441 1.0616762480036592 0.2883826857433824 1.0 0.837285428130992 2 Q13546 1
Sialic acid metabolism 0.6058042914018023 1.0616049023893952 0.2884150872254976 1.0 0.837285428130992 5 P16278 1
Depolymerisation of the nuclear lamina 0.4922097149920874 1.0140243079750506 0.3105711534799635 1.0 0.8744312498253444 10 P14635,P02545 2
Diseases associated with n glycosylation of proteins 0.5453243266674108 0.9832492487156724 0.3254847815278074 1.0 0.8819178290909403 7 Q2TAA5,O75340,Q9BT22,Q9BV10 4
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7886574623572005 0.975352517775568 0.3293854279930612 1.0 0.885571527371233 3 Q8NB78 1
Caspase mediated cleavage of cytoskeletal proteins 0.496835007147441 0.9705118774233196 0.331791407453756 1.0 0.885571527371233 9 P35611,Q15149,P08670 3
Regulation of gene expression in beta cells 0.7750596658711246 0.9649985644154608 0.3345455308279965 1.0 0.885571527371233 2 P31751 1
Pre notch processing in golgi 0.7857356013130316 0.9649511077424298 0.3345693011440662 1.0 0.885571527371233 3 Q15363,Q9UBV2 2
Signaling by flt3 fusion proteins 0.6328358208955278 0.9491465742513188 0.3425460694809823 1.0 0.8941850655046905 4 Q01082,Q92614,P62993 3
Keratan sulfate degradation 0.6314142014310246 0.9434930892388164 0.345428748473805 1.0 0.8991497385366835 4 P06865,P16278 2
Wnt mediated activation of dvl 0.77588779468815 0.9300201530338442 0.3523606501314591 1.0 0.9070024142272743 3 P68400,P67870 2
Cdc42 gtpase cycle 0.3396949778424212 0.9253513173814994 0.3547831931552552 1.0 0.9089433131663716 34 Q9UQB8,Q14344,Q86YQ8,P14923,P02786,Q96N67,Q9Y5S2,O15498,P46940,Q14739 10
Phosphorylation of emi1 0.7737988660101368 0.9226370152216268 0.356196399154691 1.0 0.9089433131663716 3 P14635,P53350 2
Activation of nima kinases nek9 nek6 nek7 0.5733622412356094 0.9220437219278116 0.3565057702887957 1.0 0.9089433131663716 5 P14635,P53350,O95067 3
Irs mediated signalling 0.6246415180942851 0.9166193003652684 0.359342167085696 1.0 0.9114700953451048 4 P31751,Q99570 2
Acyl chain remodelling of pg 0.7592482100238682 0.9048080295147106 0.3655670970922122 1.0 0.9140785601934102 2 Q92604 1
Assembly of the hiv virion 0.7568615751789995 0.8957866420744868 0.3703667254953193 1.0 0.9140785601934102 2 Q99816 1
Metabolism of steroid hormones 0.534682415474711 0.8955802412970166 0.3704769924221143 1.0 0.9140785601934102 6 Q53GQ0,P30536 2
Recycling of eif2 gdp 0.5251968334462562 0.8898079591046997 0.3735690121676485 1.0 0.9141917727342104 7 P49770,Q9NR50 2
Cation coupled chloride cotransporters 0.7488066825775694 0.8654755905046727 0.3867778077828494 1.0 0.925025243739288 2 Q9Y666 1
Triglyceride metabolism 0.5197593857947703 0.8647363301066082 0.3871835243091579 1.0 0.925025243739288 7 Q9HCL2 1
Switching of origins to a post replicative state 0.3064872087778579 0.8620796306697548 0.3886436995278735 1.0 0.925025243739288 59 P49721,Q9UJX2,P25787,P28070,Q14997,Q9UBD5,P28072,O43242,O00231,Q15008,Q14566,Q9UJX5,Q9UJX4,Q9Y619,Q9H1A4,P20618 16
Beta oxidation of pristanoyl coa 0.5576687898781755 0.8553537184087401 0.3923553570833076 1.0 0.9290867910490588 5 O14734,O15254 2
Response to elevated platelet cytosolic ca2 0.3461791022267208 0.8541176037986862 0.3930398309500016 1.0 0.929124770443031 31 Q8NBX0,Q08380,P12814,P07602,Q9Y6I9 5
Regulation of cholesterol biosynthesis by srebp srebf 0.3597890599861843 0.843052245267496 0.3991992250205098 1.0 0.9390801224353826 27 Q16850,Q9UBM7,O75845,P48449,Q9HCL2,Q14534 6
Anchoring of the basal body to the plasma membrane 0.3400933957321787 0.8397044219742983 0.4010741340342414 1.0 0.9390801224353826 32 Q15154,Q13409,Q14203,P17612,Q99996,P41208,Q7Z4H7,O75935,P53350,Q9UIS9,O94927,Q14204,Q7Z460,P62258,Q15019,P06493,Q96CS2 17
Activation of smo 0.7500828626471451 0.8395583230639114 0.4011560752481791 1.0 0.9390801224353826 3 Q9Y496 1
Translocation of slc2a4 glut4 to the plasma membrane 0.3296645329478501 0.8387776168476943 0.4015941134452074 1.0 0.9390801224353826 40 Q86X10,Q96KP1,Q9UPT5,P61026,Q96A65,Q9UIQ6,Q9BUF5,P11233,P31751,Q9Y496,P35579,P31946,Q8TAG9 13
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3956784283277366 0.8377557623749465 0.4021678885287529 1.0 0.9390801224353826 16 Q07065,Q9BTY2,Q02818 3
Rhou gtpase cycle 0.3860676350663201 0.8331670114758958 0.4047505446394219 1.0 0.942384015157113 18 O43396,P62993,Q92783,Q13813,P46940,Q14155 6
Abc family proteins mediated transport 0.3183870513942223 0.8130922051686454 0.4161651952089875 1.0 0.953147663014738 50 P49721,O75027,P56589,P28070,Q14997,O43242,O15439,P28072,O00231,Q15008,Q9BUN8,P40855,Q9UBV2,P25787,P08183,P20618 16
Rac2 gtpase cycle 0.3258952132255922 0.7960173266013449 0.4260219646387579 1.0 0.9568916197515248 36 Q14185,O15173,Q5T2T1,Q86XL3,Q13505,P50402,P46940,Q14739,Q7L576 9
Recruitment of numa to mitotic centrosomes 0.3255904643421546 0.7934152070452033 0.4275359536514611 1.0 0.9574918101969268 37 Q14203,P17612,P41208,Q7Z4H7,O75935,P53350,O94927,Q7Z460,Q96CW5,P06493,Q9BUF5,Q9BSJ2 12
Role of phospholipids in phagocytosis 0.5911042369161424 0.7853437699009235 0.432252039504406 1.0 0.9576617185673756 4 Q8IV08 1
E2f mediated regulation of dna replication 0.4369598424895687 0.7811112218711476 0.4347370823136791 1.0 0.9576617185673756 11 P14635,Q9UBD5,Q9Y619 3
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4598673929954065 0.7796701114532966 0.4355850758691899 1.0 0.9580114801553384 9 Q9UJX2,Q96DE5,Q9UJX5,Q9UJX4,Q9H1A4 5
Nrif signals cell death from the nucleus 0.7252386634844911 0.7781450250489818 0.4364835217353691 1.0 0.9584709245057867 2 Q13501 1
Activation of the pre replicative complex 0.3651765723170544 0.7635750767073233 0.4451205063922994 1.0 0.9678660380985222 20 P35244,Q9UBD5,P15927,Q14566,Q9Y619,Q07864 6
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4324745936572511 0.7563236993688289 0.4494551422843194 1.0 0.9683317264935364 11 P38435,Q9HA64,O60725 3
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.5029817654146721 0.7546883967999429 0.4504359702018501 1.0 0.9683317264935364 6 O15111,Q13546 2
Transcriptional regulation by mecp2 0.3881410187917506 0.7462699808890871 0.4555043415231328 1.0 0.9710905440447156 14 Q14739,P42858 2
Regulation of hmox1 expression and activity 0.3160166750436909 0.7343448253345594 0.4627386047834219 1.0 0.9758543357009918 45 P49721,P68400,P28070,Q14997,P09601,P28072,O43242,O00231,Q15008,P67870,P25787,Q8TCT9,P20618 13
Muscle contraction 0.3486325157329542 0.7327062611987922 0.4637376043499222 1.0 0.9758543357009918 26 Q14571,P07355,P17612,P06753,P16615,P08670,P04083,P67936 8
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3565749320981154 0.723832642879404 0.4691684863413092 1.0 0.9836262383324584 22 O75340,Q2TAA5,Q9BT22,Q9BV10,P10619,P16278,Q86YN1,Q13630 8
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.7091288782816261 0.7198093978956536 0.471642357806767 1.0 0.9870689836399954 2 P11802 1
Transcriptional regulation by ventx 0.3835156658183914 0.7171946447281506 0.4732540031899761 1.0 0.9870689836399954 14 Q9UJX2,Q9HCE1,P42771,Q9UJX4,Q9H1A4 5
Cellular response to chemical stress 0.2916841115321579 0.7169797789921855 0.4733865737405507 1.0 0.9870689836399954 76 P28070,P30519,O00231,Q15008,P15954,P49721,Q14997,P28072,P60900,Q9Y6N1,Q8TCT9,P20618,P13073,Q8TED1,P09601,P00403,P67870,P68400,O43242,Q5RI15,O75880,P25787,P30043 23
Netrin 1 signaling 0.4058806363365721 0.7151818700363037 0.4744966703050144 1.0 0.9870689836399954 12 Q00169 1
Abc transporters in lipid homeostasis 0.7105341689047961 0.7048421172739923 0.4809084949140176 1.0 0.9975132009796388 3 P40855,P56589 2
Retrograde transport at the trans golgi network 0.3763570403968153 0.6907873065551585 0.4896992136476128 1.0 1.0 15 Q9UID3,Q5VZE5,P20645,Q14746 4
Runx3 regulates p14 arf 0.6992840095465429 0.68478969529909 0.4934766388438905 1.0 1.0 2 P42771 1
Er to golgi anterograde transport 0.2882662009958234 0.6838232836986453 0.4940867619632141 1.0 1.0 80 O15020,O15084,P24390,Q14203,O43237,O15498,Q9Y3B3,O95249,Q14746,Q9H0U4,Q13190,Q9Y6G9,P49755,Q9UJW0,O14653,Q15363,P84085,Q9BUF5,P61923,O75935,Q96JB2 21
Peroxisomal lipid metabolism 0.3778302887853615 0.681704250649792 0.4954259791338022 1.0 1.0 14 Q15067,Q9BY49 2
Caspase activation via extrinsic apoptotic signalling pathway 0.4812718697432714 0.6607173405730824 0.5087936010873191 1.0 1.0 6 Q13546,Q14790 2
Aurka activation by tpx2 0.314729058370451 0.657299124935479 0.5109885990493221 1.0 1.0 33 Q15154,Q13409,Q14203,P17612,Q99996,P41208,Q7Z4H7,O75935,P53350,Q9UIS9,O94927,Q14204,Q7Z460,O14965,P62258,P06493,Q96CS2 17
Fatty acyl coa biosynthesis 0.3710323543165172 0.6572503587700985 0.5110199498668502 1.0 1.0 15 Q53GQ0,Q6Y1H2,Q9NZ01,P50897 4
Mitotic g1 phase and g1 s transition 0.2866874497165827 0.6538400269982426 0.5132148755780823 1.0 1.0 76 P28070,P14635,Q9UBD5,P00374,Q15008,O00231,P42771,Q14566,P51665,P49721,P28072,P60900,P63151,P31751,P20618,P11802,P35244,O43242,P15927,P06493,P25787,Q9Y619,Q07864 23
Unfolded protein response upr 0.3097267846032207 0.6525132788532465 0.5140701094439706 1.0 1.0 41 P43307,O14773,O95070,P49748 4
Mapk6 mapk4 signaling 0.3033721704623883 0.6447841757127039 0.519067058075596 1.0 1.0 49 P49721,P04792,Q9HCE1,P28070,Q14997,O43242,P28072,P60900,O00231,Q15008,Q16181,P06493,P25787,P20618,P51665 15
Vegfr2 mediated vascular permeability 0.4114035592738198 0.641595491242079 0.521135861238939 1.0 1.0 11 P14923,P31751 2
Regulation by c flip 0.5529024458230327 0.6409664444188927 0.5215444845338977 1.0 1.0 4 Q13546 1
Caspase activation via death receptors in the presence of ligand 0.5529024458230327 0.6409664444188927 0.5215444845338977 1.0 1.0 4 Q13546 1
Interleukin receptor shc signaling 0.6849642004773306 0.6348074577343485 0.5255539987606017 1.0 1.0 2 P62993 1
Diseases of immune system 0.5024361174433528 0.6280957043468631 0.5299412469553826 1.0 1.0 5 O15111,P09429 2
Regulation of plk1 activity at g2 m transition 0.3075513510505315 0.6278496673863265 0.5301024259587395 1.0 1.0 38 Q14203,P17612,P41208,Q7Z4H7,O75935,P14635,P53350,O95067,O94927,Q7Z460,O14974,P06493 12
Copi independent golgi to er retrograde traffic 0.3263481215527117 0.6278071665402687 0.530130270818197 1.0 1.0 29 Q9Y6G9,Q14203,O75935,Q9UJW0,Q8TD16,O43237,Q9BUF5 7
Apoptotic execution phase 0.3218651686353945 0.6187990190837764 0.5360487685066029 1.0 1.0 30 P35611,P02545,P51572,P15924,Q15149,P08670,O00429,Q9UDY2 8
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5450746268656794 0.6122911664679718 0.5403451330632936 1.0 1.0 4 P54619,P54646,Q16539 3
Cdt1 association with the cdc6 orc origin complex 0.3046770002217809 0.6056006071116083 0.5447799990973281 1.0 1.0 41 P49721,P28070,Q14997,Q9UBD5,P28072,O43242,O00231,Q15008,P25787,Q9Y619,P20618 11
Vitamin d calciferol metabolism 0.6799449086062864 0.6050215757624618 0.5451646608945713 1.0 1.0 3 P04062 1
Peptide hormone metabolism 0.367701459301797 0.6043157928238686 0.5456337084979836 1.0 1.0 13 Q96KP1,Q9UPT5,P67812 3
Collagen formation 0.3647923134842389 0.5869184165335409 0.5572585003878254 1.0 1.0 13 Q15149,O60568 2
Interleukin 15 signaling 0.6685560859188586 0.5790872308104429 0.5625303156024768 1.0 1.0 2 P62993 1
Interleukin 7 signaling 0.6685560859188585 0.5790872308104419 0.5625303156024775 1.0 1.0 2 P51532 1
Rip mediated nfkb activation via zbp1 0.454003295121882 0.5716692235884625 0.5675460884368162 1.0 1.0 7 O15111 1
Transport to the golgi and subsequent modification 0.2787451129401119 0.5695726424831736 0.5689675880388587 1.0 1.0 82 O15020,O15084,P24390,Q14203,O43237,O15498,Q9Y3B3,O95249,Q14746,Q9H0U4,Q13190,Q9Y6G9,P49755,Q9UJW0,O14653,Q15363,P84085,Q9BUF5,P61923,O75935,Q96JB2 21
Apc cdc20 mediated degradation of nek2a 0.3975603379050957 0.5681684576594014 0.5699205871368906 1.0 1.0 11 Q9UJX2,O60566,Q16763,Q96DE5,Q9UJX5,Q9UJX4,Q9H1A4 7
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3975603379050957 0.5681684576594014 0.5699205871368906 1.0 1.0 11 Q9UJX2,O60566,Q16763,Q96DE5,Q9UJX5,Q9UJX4,Q9H1A4 7
Condensation of prophase chromosomes 0.3795681719537446 0.565605625265793 0.5716619029700292 1.0 1.0 12 Q9UPP1,Q01105,P14635,P53350,P42695,P06493,Q86XI2 7
Cyclin a b1 b2 associated events during g2 m transition 0.3773939392773871 0.5535601589500719 0.5798798985949323 1.0 1.0 12 P14635,P53350,P63151,O95067 4
Respiratory electron transport 0.2872563052011871 0.5432967543787947 0.5869254985816932 1.0 1.0 54 O14949,P22695,Q9Y6M9,Q8IUX1,Q9P0J0,Q8TB37,P00403,O75306,Q9BQ95,P15954,Q9NPL8,P21912,O75880,Q9Y6N1,O43676,Q9UDW1 16
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.2758648444851844 0.5396672615078016 0.5894265214874652 1.0 1.0 64 O14949,P22695,Q9Y6M9,Q8IUX1,Q9P0J0,Q8TB37,O75964,P00403,O75306,Q9BQ95,P15954,Q9NPL8,P21912,O75880,Q9Y6N1,O43676,Q9UDW1 17
Rhob gtpase cycle 0.3313892500740815 0.5376969094007336 0.5907863132867528 1.0 1.0 21 O75116,P14923,O75955,Q9UDY2,P41440 5
Basigin interactions 0.4285262075723371 0.5363566380239662 0.5917120937341291 1.0 1.0 8 P53985 1
Rhobtb3 atpase cycle 0.6526410026857636 0.520104274553866 0.6029908992618371 1.0 1.0 3 P51151,Q13618 2
Cytochrome p450 arranged by substrate type 0.6524990445957334 0.5196746105548037 0.6032903858486272 1.0 1.0 3 Q16850 1
Ticam1 rip1 mediated ikk complex recruitment 0.5180181591222734 0.5161990861693393 0.6057153684739445 1.0 1.0 4 O15111 1
Transcriptional regulation by runx2 0.287833413658122 0.510726926389068 0.6095422834093496 1.0 1.0 51 P49721,P28482,P28070,Q14997,P14635,P28072,O43242,O00231,Q15008,P17931,P31751,P11802,P25787,P20618 14
Smad2 smad3 smad4 heterotrimer regulates transcription 0.4713547449891964 0.5080693726168312 0.6114046932404271 1.0 1.0 5 P28482,P50750 2
Parasite infection 0.3224313824702818 0.5067741237085502 0.612313314492559 1.0 1.0 24 Q9UQB8,Q14185,P28482,Q96F07,P35579,Q7L576 6
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.2907948474839149 0.5041004154324791 0.614190815019132 1.0 1.0 47 P49721,Q9UJX2,P25787,P28070,Q14997,O43242,P53350,P28072,O00231,Q15008,Q9UJX5,Q9UJX4,Q9H1A4,P20618 14
Ripk1 mediated regulated necrosis 0.3472759829478555 0.4971219307433104 0.6191030702658298 1.0 1.0 14 P41440,Q13546,O00560,O75955 4
Endosomal vacuolar pathway 0.5079226800610008 0.4817177995337759 0.6300064298475987 1.0 1.0 4 Q9UIQ6 1
Transcriptional regulation of white adipocyte differentiation 0.3463814836351999 0.4794050325183809 0.631650514009219 1.0 1.0 13 Q9Y2X0,O75448 2
Rhobtb gtpase cycle 0.3027553967377923 0.4699891669757993 0.6383627572460013 1.0 1.0 30 O75116,P61201,O43396,Q13464,Q8N684,P38159,Q96DH6,Q9BT78,P08670,P12814 10
Pyruvate metabolism 0.3364679487563289 0.4636857433570003 0.6428729128963333 1.0 1.0 16 P21796 1
Cytosolic iron sulfur cluster assembly 0.4108378270846775 0.4592902678067478 0.646025735612616 1.0 1.0 8 O75027,P18074,P28340 3
Signaling by fgfr4 in disease 0.6261933174224397 0.4443829369140992 0.6567657477458182 1.0 1.0 2 P62993 1
Pregnenolone biosynthesis 0.4962165314146488 0.4428028123924646 0.6579083689210867 1.0 1.0 4 P30536 1
Cd28 co stimulation 0.389363585022228 0.4384736877919426 0.6610429399604034 1.0 1.0 9 P31751,P42345 2
Rho gtpase cycle 0.266565082918838 0.4374937162556953 0.6617533322087861 1.0 1.0 163 Q14344,P30519,Q9HD26,P38159,O75955,O15498,Q07065,P67936,Q9UQB8,O95202,O43396,P51572,P15924,P08670,Q9BT78,P50402,P41440,Q13190,O15173,Q86XL3,Q13505,P12814,Q15058,Q86YQ8,Q14739,O75116,Q14185,P14923,Q15904 29
Auf1 hnrnp d0 binds and destabilizes mrna 0.2853089597780341 0.4330047569933676 0.6650113139392344 1.0 1.0 41 P49721,P04792,P28070,Q14997,O43242,P28072,P60900,O00231,Q15008,Q14103,P25787,P20618 12
Orc1 removal from chromatin 0.2794364270227282 0.4289974621527042 0.6679250715828828 1.0 1.0 51 P49721,P28070,Q14997,Q9UBD5,P28072,O43242,O00231,Q15008,Q14566,P25787,Q9Y619,P20618 12
Programmed cell death 0.2560985851656818 0.4214938351331224 0.6733945119460287 1.0 1.0 101 P35611,P28482,P28070,O00560,O00231,Q15008,P42771,O75955,Q14790,P49721,Q13546,P02545,Q13464,Q14997,P28072,P51572,P15924,P31751,P08670,P41440,P20618,Q15149,O00429,O43242,Q9UDY2,P25787 26
Polo like kinase mediated events 0.4168351043465306 0.4197160019381135 0.6746929338497043 1.0 1.0 7 P49454,P14635,P53350,O95067,Q99640 5
Rhog gtpase cycle 0.2827366499978106 0.4177298305545632 0.6761446594662943 1.0 1.0 36 Q13190,Q14185,O95202,O15173,Q86XL3,O15498,Q14739 7
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4007672974110933 0.4169691017531942 0.6767010081696339 1.0 1.0 8 P51812,Q92796,P28482 3
Fanconi anemia pathway 0.4139499331095324 0.4085247333117026 0.6828884760447118 1.0 1.0 7 P35244,P15927 2
Signaling by alk in cancer 0.2800872114538679 0.40423244959415 0.6860417937964445 1.0 1.0 34 Q13501,P28482,P06753,Q9H6R7,P35579,P67936 6
Rab gefs exchange gtp for gdp on rabs 0.3014482308809708 0.4038767334162519 0.6863033663630236 1.0 1.0 27 P61026,P20339,Q14C86,P61020,P51151,Q9H0U4,P31751,Q15042 8
Prevention of phagosomal lysosomal fusion 0.4836209721884258 0.4023278404693718 0.6874427680455006 1.0 1.0 4 P20339 1
Biological oxidations 0.280192500146476 0.3973871207138637 0.6910820114733551 1.0 1.0 45 O43169,Q16850,Q9NUJ1,O00170,P07099 5
Rap1 signalling 0.6073652290726418 0.3903321125424557 0.6962909804338839 1.0 1.0 3 P31946 1
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.4085067394303643 0.3876844843321599 0.6982495392318244 1.0 1.0 7 O95864 1
Apoptotic factor mediated response 0.4084660441830887 0.3875300546115369 0.698363839401924 1.0 1.0 7 P28482 1
Dna damage reversal 0.437643861508481 0.3874861921111294 0.6983963051985824 1.0 1.0 5 Q8N3C0 1
Regulation of beta cell development 0.4787775067856713 0.3871765633417428 0.698625499450962 1.0 1.0 4 P31751 1
Tnfr1 induced proapoptotic signaling 0.4787285129261712 0.3870245197343866 0.6987380556452942 1.0 1.0 4 Q13546,Q14790 2
Notch4 activation and transmission of signal to the nucleus 0.6053102625298388 0.3837276759071791 0.7011802976899537 1.0 1.0 2 Q92542 1
G alpha i signalling events 0.3040139786973727 0.3835682246360636 0.7012984948569589 1.0 1.0 24 Q14571,P28482,P07602,Q9NZJ7,P04083 5
Organelle biogenesis and maintenance 0.2560370228579737 0.3697613600261862 0.7115603080898161 1.0 1.0 96 Q14203,P41208,O43924,Q96A65,Q7Z460,Q9Y496,Q3SYG4,Q8TAG9,Q96KP1,O00411,P24539,P53350,A0AVF1,O75964,O94927,Q96RR1,Q10713,P17612,Q7Z4H7,P56385,Q13505,Q6UXV4,Q16891,Q9BUF5,Q9UPT5,O75935,P54646,Q15019,P06493 29
Rac1 gtpase cycle 0.2754032570716745 0.3638736031804218 0.7159523970053976 1.0 1.0 47 Q9UQB8,Q14185,Q14344,Q5T2T1,Q96N67,Q96F07,P50402,O15498,P46940,Q14739,Q7L576 11
Association of tric cct with target proteins during biosynthesis 0.3085846564683245 0.3609030712629519 0.7181719075763935 1.0 1.0 19 P04062 1
Signalling to ras 0.5959415099970117 0.3601542934037816 0.7187317528889248 1.0 1.0 3 P11233,P62993 2
P38mapk events 0.5957637231503641 0.3574409649177421 0.7207617139591007 1.0 1.0 2 P11233 1
Rac3 gtpase cycle 0.273954676582758 0.3567774122724398 0.7212584472979349 1.0 1.0 34 Q9UQB8,O15173,Q5T2T1,P50402,O15498,Q14739,Q7L576 7
Fcgamma receptor fcgr dependent phagocytosis 0.277454323681319 0.3554083819511835 0.7222836703472544 1.0 1.0 33 Q14571,Q9UQB8,Q14185,P28482,Q96F07,P35579,Q8IV08,Q7L576 8
Constitutive signaling by aberrant pi3k in cancer 0.4038231780167089 0.355017573249888 0.7225764261129788 1.0 1.0 6 Q9NWH9,O43815,P62993,P63000,P84095 5
Gastrin creb signalling pathway via pkc and mapk 0.4273876440233071 0.3532475326601421 0.7239028759515855 1.0 1.0 5 P28482,P62993 2
Regulation of pten stability and activity 0.2756065086119225 0.3523624282044445 0.7245664753214518 1.0 1.0 42 P49721,P68400,P28070,Q14997,O43242,P28072,P60900,O00231,Q15008,P19784,P31751,P67870,P25787,P20618 14
Cristae formation 0.3024134595335813 0.3485376709795809 0.7274364278489518 1.0 1.0 20 O75964 1
Caspase activation via dependence receptors in the absence of ligand 0.5906921241050183 0.3438649244041584 0.730947871354027 1.0 1.0 2 Q9Y5V3 1
Nade modulates death signalling 0.590692124105018 0.3438649244041573 0.7309478713540278 1.0 1.0 2 P62258 1
Flt3 signaling in disease 0.4005338602197918 0.3434713683520332 0.7312438769167127 1.0 1.0 6 Q01082,Q92614,P62993 3
Hedgehog on state 0.2742125018339291 0.3409785944303662 0.7331196962936501 1.0 1.0 42 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P48729,Q9Y496,P25787,P20618 11
Clec7a inflammasome pathway 0.5855190247951235 0.3336307544931815 0.7386582079795847 1.0 1.0 3 Q14790 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.2698273801558663 0.3322269510314981 0.7397178944429521 1.0 1.0 50 P49721,P25787,P28070,Q14997,P14635,P53350,P28072,O00231,Q15008,P60900,O43242,O95067,P06493,Q9BUF5,P20618 15
Negative regulation of the pi3k akt network 0.319346819943217 0.3319468837856096 0.7399293674834597 1.0 1.0 13 P28482,P62993,P31751,Q8TBX8,P84095 5
Asparagine n linked glycosylation 0.2353791771513316 0.3314189918973712 0.7403280212778531 1.0 1.0 123 O15020,O15084,P24390,Q14203,O75340,P16278,Q9UBV2,O43237,O15498,Q9Y3B3,O95249,Q14746,Q2TAA5,Q9H0U4,Q86YN1,Q13190,Q9Y6G9,P49755,Q9UJW0,O14653,Q9BT22,Q9BUN8,Q9BV10,Q15363,P84085,Q9BUF5,Q13630,P61923,O75935,P10619,Q9Y6B6,Q96JB2 32
Complex i biogenesis 0.2903858711835218 0.3301582698813807 0.7412803763056266 1.0 1.0 27 Q9Y6M9,Q8IUX1,Q9P0J0,O75306,Q9NPL8,Q9BQ95,O43676 7
Fceri mediated ca 2 mobilization 0.4197835566292922 0.3286988611440958 0.7423833152202173 1.0 1.0 5 Q14571,Q08209 2
Glutathione synthesis and recycling 0.3950970888615842 0.3247116161081944 0.7453993422866658 1.0 1.0 6 O75223,Q96KP4,P48507 3
Signal attenuation 0.5814998160388067 0.3236698531855473 0.7461879968945355 1.0 1.0 3 P28482 1
Signaling by braf and raf1 fusions 0.2926689712754957 0.3217967922711142 0.7476066445505578 1.0 1.0 25 P02545,Q99996,P28482,Q9NRY5,O00203,P51114,Q96PU8,P46940,P31946 9
Regulation of ras by gaps 0.2710504409565089 0.3201003812782098 0.7488922366382476 1.0 1.0 38 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P21359,P25787,P20618 10
Apoptosis 0.2548409897653541 0.3137451898398967 0.7537145759068196 1.0 1.0 90 P35611,P28482,P28070,O00231,Q15008,P42771,Q14790,P49721,Q13546,P02545,Q13464,Q14997,P28072,P51572,P15924,P31751,P08670,P20618,Q15149,O00429,O43242,Q9UDY2,P25787 23
Defective cftr causes cystic fibrosis 0.2702167179936305 0.3099830887838566 0.7565738165698077 1.0 1.0 40 P49721,P28070,Q14997,O43242,P28072,Q9BUN8,O00231,Q15008,Q9UBV2,P25787,P20618 11
Abc transporter disorders 0.2702167179936305 0.3099830887838566 0.7565738165698077 1.0 1.0 40 P49721,P28070,Q14997,O43242,P28072,Q9BUN8,O00231,Q15008,Q9UBV2,P25787,P20618 11
Energy dependent regulation of mtor by lkb1 ampk 0.3592587291922142 0.3099505221329867 0.7565985822225314 1.0 1.0 9 Q9Y376,Q15382,P42345 3
Rab geranylgeranylation 0.3016721507595828 0.301207201396545 0.7632564987616342 1.0 1.0 18 Q969Q5,P61020,P20339,Q9H0U4 4
Rhoq gtpase cycle 0.2916908646254618 0.2993843143144083 0.7646468290040407 1.0 1.0 23 P14923,Q5T2T1,P02786,Q9HD26,Q9Y5S2,Q86YQ8,P46940 7
Runx1 regulates transcription of genes involved in differentiation of hscs 0.2686180497945042 0.2976534765717873 0.7659676550110504 1.0 1.0 40 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,Q03164,P25787,P20618 10
Regulation of lipid metabolism by pparalpha 0.2910880859396381 0.290211288932924 0.7716546003646352 1.0 1.0 22 P04035,O75448,Q15067,P23786 4
Zbp1 dai mediated induction of type i ifns 0.3679560763525224 0.2886747747243788 0.7728302681013872 1.0 1.0 8 O15111 1
Apc c mediated degradation of cell cycle proteins 0.2598950367192794 0.286354315726946 0.7746067610096841 1.0 1.0 55 P49721,Q9UJX2,P25787,P28070,Q14997,P14635,P53350,P28072,O00231,Q15008,O43242,Q9UJX5,Q9UJX4,Q9H1A4,P20618 15
Defective ripk1 mediated regulated necrosis 0.5652222388768715 0.2849144489024555 0.7757096859573738 1.0 1.0 3 Q13546 1
Synthesis of bile acids and bile salts 0.3666482921959781 0.2839074334394111 0.7764813197417826 1.0 1.0 8 Q9H4L5,Q9BZF3 2
Bile acid and bile salt metabolism 0.3666482921959781 0.2839074334394111 0.7764813197417826 1.0 1.0 8 Q9H4L5,Q9BZF3 2
Regulation of runx1 expression and activity 0.5646476872307088 0.2835941736962813 0.7767214025939164 1.0 1.0 3 Q9HCE1 1
Rnd2 gtpase cycle 0.2982989599871681 0.283079722416642 0.7771157252823839 1.0 1.0 18 P38159,Q07065,Q15058 3
Autophagy 0.2582740558610628 0.2825144212635297 0.7775490902033608 1.0 1.0 56 Q99816,Q9NT62,P21796,O43237,Q8IWA4,P50542,O96008,Q9NS69,Q8NCE2,P08670,Q99570,Q13501,Q9Y6G9,Q8N4H5,Q15382,P42345,P67870,Q9BUF5,Q9Y4P1,P68400,P19784 21
Dscam interactions 0.4420895522388123 0.2807653599288037 0.7788903740903683 1.0 1.0 4 Q16512,Q13153,Q16539 3
Signaling by ntrk2 trkb 0.4037025977903785 0.2793082073422918 0.7800083082859595 1.0 1.0 5 P63000,P62993,Q00535,P19174 4
Diseases associated with glycosylation precursor biosynthesis 0.3644683109150282 0.2760254492284364 0.7825285196096292 1.0 1.0 8 P16278 1
Clec7a dectin 1 induces nfat activation 0.5608506014107639 0.2749524471452087 0.783352772350193 1.0 1.0 3 Q14571 1
Dna replication initiation 0.4009646307071955 0.2712585804625845 0.7861921605355544 1.0 1.0 5 Q9NR33,P49643,Q07864 3
Formation of incision complex in gg ner 0.3009968979071119 0.2682530828445712 0.7885045175224015 1.0 1.0 16 P41208,P35244,P15927,O75925,P18074 5
Regulation of runx3 expression and activity 0.2625514759921054 0.2639810499669232 0.7917945209018695 1.0 1.0 36 P49721,P28070,O43242,P28072,O00231,Q15008,P42771,P25787,P20618 9
Cross presentation of soluble exogenous antigens endosomes 0.261888629276471 0.2592867207697891 0.7954140244443355 1.0 1.0 36 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P25787,P20618 9
Degradation of axin 0.261888629276471 0.2592867207697891 0.7954140244443355 1.0 1.0 36 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P25787,P20618 9
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.5557875894988138 0.2582380961724856 0.7962231582418897 1.0 1.0 2 P52292 1
Camk iv mediated phosphorylation of creb 0.5557875894988138 0.2582380961724856 0.7962231582418897 1.0 1.0 2 P52292 1
Signaling by erbb4 0.374319534924819 0.2570086974979128 0.7971720589143225 1.0 1.0 6 P61201,P62993,Q92542 3
Transcriptional regulation of granulopoiesis 0.3723618993789857 0.2509759863236495 0.8018326752389968 1.0 1.0 6 Q03164 1
Rhoc gtpase cycle 0.2709923984884905 0.2492483775641496 0.8031686600571832 1.0 1.0 30 Q13190,O75116,P41440,P14923,O75955,Q9UDY2,P46940,Q14739 8
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.2990357835954004 0.2480983476194368 0.8040583140677084 1.0 1.0 15 P09601 1
Ret signaling 0.3926545237384238 0.2474994121202164 0.8045217464097296 1.0 1.0 5 Q06124,P17612,P62993,P19174 4
Signaling by the b cell receptor bcr 0.2591064010380713 0.2462359873207682 0.8054995591325329 1.0 1.0 51 P49721,Q14571,Q08209,P28070,Q14997,O15111,P28072,O43242,O00231,Q15008,P25787,P20618,P62942 13
Downstream signaling events of b cell receptor bcr 0.2603066575232788 0.2414725976467421 0.809188852097865 1.0 1.0 48 P49721,Q08209,P28070,Q14997,O15111,P28072,P60900,O00231,Q15008,O43242,Q9UDY8,P25787,P20618,P62942 14
O linked glycosylation 0.4248443511454484 0.2364141312860644 0.8131113317687928 1.0 1.0 4 Q10472,O43505 2
O linked glycosylation of mucins 0.4248443511454484 0.2364141312860644 0.8131113317687928 1.0 1.0 4 Q10472,O43505 2
Oncogenic mapk signaling 0.2688451420679218 0.2358816001810421 0.8135245463553293 1.0 1.0 30 P02545,Q99996,P28482,Q9NRY5,O00203,P51114,Q99956,P21359,Q96PU8,P46940,P31946 11
Pexophagy 0.5425996400129096 0.2354903663122568 0.8138281552101114 1.0 1.0 3 Q13501 1
Selective autophagy 0.2591930044705184 0.2330659559810817 0.8157101901756452 1.0 1.0 38 O96008,Q13501,Q9NS69,Q9Y6G9,Q8N4H5,P68400,P21796,P08670,P67870,O43237,Q9BUF5,Q8IWA4,P50542 13
Constitutive signaling by akt1 e17k in cancer 0.3658972244024184 0.2315019105520886 0.8169249013433437 1.0 1.0 6 O15111,P31751 2
Signaling by egfr in cancer 0.3860853986264541 0.2294542443500443 0.8185158796535348 1.0 1.0 5 P22681,Q16543,P62993,P19174 4
Constitutive signaling by egfrviii 0.3860853986264541 0.2294542443500443 0.8185158796535348 1.0 1.0 5 P22681,Q16543,P62993,P19174 4
Constitutive signaling by ligand responsive egfr cancer variants 0.3860853986264541 0.2294542443500443 0.8185158796535348 1.0 1.0 5 P22681,Q16543,P62993,P19174 4
Signaling by erbb2 in cancer 0.3860853986264536 0.2294542443500432 0.8185158796535357 1.0 1.0 5 Q96RT1,Q16543,P62993,P19174 4
Signaling by erbb2 ecd mutants 0.3860853986264536 0.2294542443500432 0.8185158796535357 1.0 1.0 5 Q96RT1,Q16543,P62993,P19174 4
Rho gtpases activate paks 0.2983142351390916 0.2286669238866287 0.8191278045819668 1.0 1.0 13 Q7Z406 1
Ngf stimulated transcription 0.5374481651700972 0.2249887209787792 0.8219880486932194 1.0 1.0 3 P50570 1
Fc epsilon receptor fceri signaling 0.2485944042636592 0.2174110308514352 0.8278880354127787 1.0 1.0 58 P49721,Q14571,Q08209,P28482,P28070,Q14997,O15111,P28072,O43242,O00231,Q15008,P49427,P25787,P20618 14
Advanced glycosylation endproduct receptor signaling 0.3468900874753643 0.2155786341482664 0.8293162116783888 1.0 1.0 8 P17931 1
Akt phosphorylates targets in the cytosol 0.3799355381285069 0.2131683478270563 0.8311956556353606 1.0 1.0 5 O15111 1
Cell cell communication 0.270401968599481 0.2089767615293396 0.8344663797097345 1.0 1.0 27 P12814,P14923,Q15149,Q9Y5K6 4
Intraflagellar transport 0.2920059517028784 0.206683817740565 0.8362567960988343 1.0 1.0 14 Q9Y496 1
Tbc rabgaps 0.3262821829413217 0.2063316785966796 0.8365318349349682 1.0 1.0 10 P61020,Q8TC07 2
Ikk complex recruitment mediated by rip1 0.3771706444605891 0.2060417906653942 0.8367582673616989 1.0 1.0 5 O15111 1
Purine salvage 0.3547652362399976 0.2046692494831788 0.8378305471515253 1.0 1.0 7 Q01433 1
Asymmetric localization of pcp proteins 0.2544624033879523 0.204283247446218 0.8381321605379557 1.0 1.0 37 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P25787,P20618 9
Meiotic synapsis 0.2820529296425889 0.2008990716709487 0.8407774936144501 1.0 1.0 18 Q9UH99 1
Degradation of dvl 0.2530741474240843 0.1950955937172477 0.8453181120051001 1.0 1.0 37 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P25787,P20618 9
Mastl facilitates mitotic progression 0.367675123711516 0.1825093933083452 0.8551829833665716 1.0 1.0 5 P06493,P14635,P30154 3
Rab regulation of trafficking 0.254599113060054 0.1810308033785296 0.8563433978544623 1.0 1.0 32 P61026,P20339,Q14C86,P61020,P51151,Q8TC07,O95248,Q9H0U4,P31751,Q9Y296,Q9UJY4,Q15042 12
P75ntr negatively regulates cell cycle via sc1 0.5158114558472635 0.1782158372364746 0.8585534725040893 1.0 1.0 2 Q13547 1
Ra biosynthesis pathway 0.5122776548187025 0.1778422992151465 0.8588468268540845 1.0 1.0 3 Q8NBN7 1
Stabilization of p53 0.2513565133656294 0.1740809779275706 0.861801822356836 1.0 1.0 40 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P42771,P25787,P20618 10
Senescence associated secretory phenotype sasp 0.2673651165674551 0.1622930980595308 0.871075049580389 1.0 1.0 21 Q9UJX2,P28482,P42771,P11802,Q9UJX4,Q9H1A4 6
Ephrin signaling 0.3398373515324887 0.1603555739082911 0.872600983565196 1.0 1.0 6 O00560 1
Cell junction organization 0.2742051804843256 0.1529079218228808 0.87847088866714 1.0 1.0 17 Q15149,P12814 2
Constitutive signaling by overexpressed erbb2 0.3859701492537358 0.1514460740345088 0.8796238467491184 1.0 1.0 4 Q96RT1,Q16543,P62993 3
Fceri mediated nf kb activation 0.247941860334656 0.1454101414342156 0.8843870580592252 1.0 1.0 46 P49721,P28070,Q14997,O15111,P28072,P60900,O00231,Q15008,O43242,P49427,Q9UDY8,P25787,P20618 13
Platelet calcium homeostasis 0.3796259630785119 0.1396512110454456 0.8889355764784028 1.0 1.0 4 Q14571 1
Clec7a dectin 1 signaling 0.2442226898536953 0.1390339107569113 0.8894233523661561 1.0 1.0 53 P49721,Q14571,Q08209,P28070,Q14997,O15111,P28072,O43242,O00231,Q15008,P49427,P25787,P20618,Q14790 14
Transcriptional regulation by runx1 0.2386393327640643 0.1344101133882725 0.8930782848751913 1.0 1.0 69 P49721,P68400,Q9HCE1,P28070,Q14997,O43242,P28072,O00231,Q15008,O00257,P17931,Q03164,P67870,Q96GM5,P25787,Q9HCL2,P20618 17
Nuclear signaling by erbb4 0.4847060341773228 0.1342917465653255 0.8931718794136683 1.0 1.0 3 P61201 1
Pre notch expression and processing 0.3087163785193639 0.1319462201427304 0.8950268298083233 1.0 1.0 9 Q15363,Q9UBV2,Q9HCE1 3
Hedgehog ligand biogenesis 0.2430775723023738 0.1249240710559869 0.9005836617001186 1.0 1.0 39 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,Q9UBV2,P25787,P20618 10
Signaling by alk 0.3386085398626427 0.1198656887419345 0.90458954487901 1.0 1.0 5 Q92769,P40763,Q13547,P19174 4
G1 s dna damage checkpoints 0.2428480658993896 0.1176123509414329 0.9063748182369572 1.0 1.0 41 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P42771,P25787,P20618 10
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3037369207772922 0.1175000645252356 0.906463792914773 1.0 1.0 9 P28482,P27361,Q93008,Q9UPN9,O75909,Q13547,Q13573,P50750 8
Mtor signalling 0.2653543521245738 0.1163794447204867 0.9073518254232428 1.0 1.0 17 P62942,P31751,Q9Y376,Q15382 4
Met activates ras signaling 0.3650677843764299 0.1148244270690331 0.9085842871105976 1.0 1.0 4 Q96P70 1
Rsk activation 0.3643179387011714 0.1136299960442589 0.9095311079444036 1.0 1.0 4 P28482 1
Raf independent mapk1 3 activation 0.3167153227569415 0.1055710181204234 0.9159227204073696 1.0 1.0 7 Q99956,P28482 2
Degradation of cysteine and homocysteine 0.3264326681394545 0.0979268260783024 0.9219903982298768 1.0 1.0 5 Q16762,Q9UBX3 2
Mitotic g2 g2 m phases 0.2324570989818247 0.092459535241456 0.9263329396589725 1.0 1.0 94 Q14203,P41208,P28070,P14635,O00231,Q15008,Q7Z460,P49721,Q14997,P53350,P60900,P63151,P28072,O94927,Q96CW5,P20618,Q7Z4H7,Q9BUF5,O75935,O43242,O95067,O14974,P06493,P25787,Q9BSJ2 25
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.3090007889234771 0.0889744827967431 0.9291021894512056 1.0 1.0 7 O15111,Q00653,P09429 3
Dna replication pre initiation 0.2294305146958442 0.0874652194538646 0.930301730304722 1.0 1.0 61 P49721,P28070,Q14997,Q9UBD5,P28072,P35244,O00231,Q15008,O43242,P15927,Q14566,P25787,Q9Y619,P20618 14
Dap12 signaling 0.441957624589666 0.0832642031967769 0.9336414631334228 1.0 1.0 3 P62993,P19174 2
Fceri mediated mapk activation 0.2908819133034509 0.0830220374292084 0.9338340167682332 1.0 1.0 9 P28482,P19174,P27361,Q16512,P62993,P63000,P45985,Q13153 8
Post translational modification synthesis of gpi anchored proteins 0.3157901311643822 0.0808276499700171 0.935579018509938 1.0 1.0 5 O43292 1
Ub specific processing proteases 0.2337783556152519 0.0785528260743428 0.9373883108690232 1.0 1.0 76 P49721,Q13546,P25787,P28070,P14735,P28072,Q9UPT9,P21796,P45880,P20618 10
Stat3 nuclear events downstream of alk signaling 0.3385074626865709 0.0774658556433687 0.9382529528739514 1.0 1.0 4 P40763,Q92769,Q13547 3
Loss of function of mecp2 in rett syndrome 0.3385074626865692 0.0774658556433662 0.9382529528739534 1.0 1.0 4 P51608,P17612,Q13547 3
Cell surface interactions at the vascular wall 0.251743939974783 0.0737225230491021 0.941231176751996 1.0 1.0 18 Q9UPY5,P78310,Q9UNN8,P53985 4
Signaling by ntrk3 trkc 0.4315129811996364 0.0736756757784942 0.941268454091332 1.0 1.0 3 P62993,P19174 2
Signal transduction by l1 0.2803747507904067 0.0722526062093272 0.9424008808312694 1.0 1.0 11 P68400,P28482,P67870 3
Rhod gtpase cycle 0.2417904387440313 0.0685902611840398 0.9453157710597716 1.0 1.0 27 Q86YQ8,Q14739,O15173,P12814 4
Regulated necrosis 0.2466116994599293 0.0640298205287972 0.9489464821714252 1.0 1.0 19 P41440,Q13546,O00560,O75955 4
Nef mediated downregulation of mhc class i complex cell surface expression 0.3000895789787918 0.0590576365900657 0.9529062008174868 1.0 1.0 5 O43747,P56377,Q9BXS5,P04439 4
Cyclin a cdk2 associated events at s phase entry 0.2328051009919637 0.0576642172333634 0.9540160967573492 1.0 1.0 42 P49721,P28070,O43242,P28072,O00231,Q15008,P31751,P11802,P25787,P20618 10
Rho gtpases activate wasps and waves 0.244623256884081 0.0570688197109043 0.9544903741947068 1.0 1.0 19 Q9UQB8,Q96F07,P28482,Q7L576 4
Frs mediated fgfr1 signaling 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr2 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Frs mediated fgfr2 signaling 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Stat5 activation 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr3 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr4 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Signaling by flt3 itd and tkd mutants 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Frs mediated fgfr3 signaling 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Frs mediated fgfr4 signaling 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Tie2 signaling 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Activated ntrk2 signals through frs2 and frs3 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr1 0.4033412887828242 0.0560081487164967 0.955335315615932 1.0 1.0 2 P62993 1
Signaling by leptin 0.4033412887828227 0.0560081487164959 0.9553353156159324 1.0 1.0 2 P40763 1
C type lectin receptors clrs 0.2295171700589308 0.0549859996820304 0.9561496175533828 1.0 1.0 57 P49721,Q14571,Q08209,P28070,Q14997,O15111,P28072,O43242,O00231,Q15008,P49427,P25787,P20618,Q14790 14
Synthesis of substrates in n glycan biosythesis 0.2495980388256239 0.0533731861718445 0.9574345690873228 1.0 1.0 16 Q86YN1,Q13630,P10619,P16278 4
Signal regulatory protein family interactions 0.4034616532378431 0.0529373181879731 0.9577818504543124 1.0 1.0 3 Q08722,P62993 2
Met activates ptpn11 0.4034616532378428 0.0529373181879731 0.9577818504543124 1.0 1.0 3 Q9NWH9,P62993 2
Downstream signaling of activated fgfr1 0.4034616532378376 0.05293731818797 0.9577818504543149 1.0 1.0 3 P62993,P19174 2
Downstream signaling of activated fgfr3 0.4034616532378376 0.05293731818797 0.9577818504543149 1.0 1.0 3 P62993,P19174 2
Downstream signaling of activated fgfr2 0.4034616532378376 0.05293731818797 0.9577818504543149 1.0 1.0 3 P62993,P19174 2
Downstream signaling of activated fgfr4 0.4034616532378376 0.05293731818797 0.9577818504543149 1.0 1.0 3 P62993,P19174 2
Pecam1 interactions 0.4034616532378372 0.0529373181879697 0.957781850454315 1.0 1.0 3 P07947,P19174 2
Transcriptional regulation by runx3 0.2313432962256823 0.0528361887046477 0.9578624273417048 1.0 1.0 41 P49721,P28070,O43242,P28072,O00231,Q15008,P42771,P25787,P20618 9
Pi3k akt signaling in cancer 0.2637255458222154 0.0527760388875276 0.957910353085385 1.0 1.0 12 O15111,P31751,P84095,P42345 4
Mitotic metaphase and anaphase 0.2243970999236441 0.0485814800953701 0.9612528292785448 1.0 1.0 141 Q92674,P28070,P14635,O00231,Q15008,Q7Z460,O43237,Q9UJX5,Q8IXJ6,Q7Z5K2,P49721,P02545,Q14997,P53350,P60900,P63151,P28072,Q8NFH4,P50402,Q9HBM1,Q8N1F7,P20618,Q9Y6G9,Q9UJX2,Q86XL3,Q5SRE5,Q14674,Q9BUF5,Q9UJX4,Q14739,Q9H1A4,Q9NTI5,Q9BTX1,O43242,Q6P1K2,O95067,Q9BS16,Q29RF7,P06493,P25787 40
Cd209 dc sign signaling 0.2905344879068322 0.0477506730474663 0.961914948881302 1.0 1.0 5 Q16512,Q04206,P17612,Q13153 4
Cytochrome c mediated apoptotic response 0.290235891310836 0.0474201701631285 0.96217835363671 1.0 1.0 5 P42574,P28482,P27361,P55210 4
Regulation of kit signaling 0.3888391524917952 0.04473708115076 0.9643168767899576 1.0 1.0 3 P07947,P62993 2
Response of eif2ak1 hri to heme deficiency 0.386153387048646 0.0434053433835763 0.9653784183132724 1.0 1.0 3 P08243,P20042 2
Kinesins 0.2381442843976262 0.0427602652527634 0.9658926387344656 1.0 1.0 22 Q9BUF5,O60333,Q9Y496 3
Gab1 signalosome 0.3840644583706357 0.0424050369653823 0.9661758130451552 1.0 1.0 3 Q06124,P62993 2
Regulated proteolysis of p75ntr 0.3651551312649234 0.0413783038914764 0.966994308967607 1.0 1.0 2 Q92542 1
Interleukin 1 processing 0.365155131264923 0.0413783038914761 0.9669943089676072 1.0 1.0 2 Q00653 1
Antigen activates b cell receptor bcr leading to generation of second messengers 0.3798716416705504 0.0404885774841205 0.9677036134226896 1.0 1.0 3 Q14571 1
Degradation of gli1 by the proteasome 0.2279410284437953 0.0390886423187349 0.9688197161666436 1.0 1.0 40 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P25787,P20618 9
Antigen processing cross presentation 0.2292653137262959 0.0358480505378657 0.9714035188794186 1.0 1.0 53 P49721,P28070,Q14997,O15111,Q9UIQ6,P28072,O00231,Q15008,O43242,Q03518,P10321,P25787,Q03519,P20618 14
Sumoylation of immune response proteins 0.365264100268577 0.0347051069930773 0.972314888590543 1.0 1.0 3 Q00653,Q9Y6K9 2
Creb phosphorylation 0.3135441527446345 0.0329601304847265 0.973706381617614 1.0 1.0 2 P51812 1
Dectin 1 mediated noncanonical nf kb signaling 0.2275411673427381 0.0278876584391019 0.9777517517553438 1.0 1.0 43 P49721,P28070,Q14997,O15111,P28072,O43242,O00231,Q15008,P25787,P20618 10
Pten regulation 0.2250060610450773 0.0263586407676331 0.9789712825641228 1.0 1.0 68 Q12873,P28482,P28070,O00231,Q15008,P49721,Q14997,P28072,P60900,O00257,P31751,P20618,Q9HCE1,Q15382,P42345,P67870,P68400,O43242,P19784,P25787 20
Cell death signalling via nrage nrif and nade 0.2530305729874981 0.0240846099686567 0.9807851192286504 1.0 1.0 12 Q13501,Q14344,Q9Y5V3,Q92542,Q14155 5
Scf skp2 mediated degradation of p27 p21 0.2247740701369415 0.0240371602543362 0.9808229676658062 1.0 1.0 40 P49721,P28070,O43242,P28072,O00231,Q15008,P11802,P25787,P20618 9
Plasma lipoprotein assembly 0.3164605828970293 0.0233346729729437 0.9813833142046742 1.0 1.0 3 Q9Y6B6 1
Regulation of tnfr1 signaling 0.2621104850853346 0.0215481417292307 0.9828084008180156 1.0 1.0 10 O15111,Q13546,Q14790 3
Activated notch1 transmits signal to the nucleus 0.2939421068337818 0.0209231084978417 0.983306992742084 1.0 1.0 3 P49407,Q92542 2
Metabolism of polyamines 0.2216747503485467 0.0182977196080362 0.9854013466521696 1.0 1.0 38 P49721,P28070,Q14997,O43242,P28072,O00231,Q15008,P25787,P20618 9
Collagen biosynthesis and modifying enzymes 0.2577375766803302 0.0155779264039434 0.9875711157249378 1.0 1.0 11 O60568 1
Potential therapeutics for sars 0.2229108071880136 0.0155506624502476 0.9875928665779556 1.0 1.0 40 Q99720,P62942 2
Tnfr2 non canonical nf kb pathway 0.2248071148335066 0.0145757052985105 0.9883706815580444 1.0 1.0 43 P49721,P28070,Q14997,O15111,P28072,O43242,O00231,Q15008,P25787,P20618 10
Traf6 mediated nf kb activation 0.2618952927268101 0.0143467168419971 0.9885533688083166 1.0 1.0 8 O15111,Q00653,P09429 3
Suppression of apoptosis 0.243747560415741 0.0140181244202503 0.9888155212611096 1.0 1.0 4 P28482 1
Meiosis 0.2271496461015234 0.013962239190356 0.9888601068597376 1.0 1.0 27 P02545,P35244,P15927,O94901,P11802,Q9UH99 6
Reproduction 0.2271496461015234 0.013962239190356 0.9888601068597376 1.0 1.0 27 P02545,P35244,P15927,O94901,P11802,Q9UH99 6
Interferon gamma signaling 0.2389607463875651 0.011962330968829 0.990455668437412 1.0 1.0 13 P10321,P19474 2
Regulation of mrna stability by proteins that bind au rich elements 0.2186065298236791 0.0026954207923019 0.9978493679691176 1.0 1.0 62 P49721,P04792,Q01105,P28070,Q14997,O43242,P28072,P60900,O00231,Q15008,Q9NQT5,Q14103,P25787,P31946,P20618 15