diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..884813dd16650df34831385d765007d0befa28c2 --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..328555340caf1b138667184fd87e12508b3dfe2e --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bf85032fa3efc9f3f23204ff6c2bfa19d61f6690a2d5ae30cb154fbc23d2590a +size 143350 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..576222c666dedf38f85a13f1234da7134c7d9a1b --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:976fac1bff3d088c938a1c61728a36c4d151527600f100f0a778cd3a65d0db85 +size 86557 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..001f67cd7d6996792f4be30f088024fa7abdbe19 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 54, + "title": "Average number of proteins per term", + "value": 2.962962962962963 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..43e2fdcebdf71e042fab437c933280e7b0dcc356 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..91ca22aa9b5eb3f68251c725e08c58bcdc26d360 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleoside diphosphate kinase, active site [IPR023005] 0.8567591763652582 2.816372053583634 0.0048569384395626 0.231191735562743 0.0262274675736385 2 P15531 1 +Peptidase family C14A, cysteine active site [IPR033139] 0.7513871449439907 2.2806444125520073 0.0225694969698586 0.7085004042254522 0.0500903767524156 4 P55212 1 +Peptidase family C14A, His active site [IPR016129] 0.7513871449439907 2.2806444125520073 0.0225694969698586 0.7085004042254522 0.0500903767524156 4 P55212 1 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.7164179104477639 2.132610474430975 0.0329566933589635 0.836288246810935 0.0580871982535335 3 P22314,Q9UBT2 2 +Protein-tyrosine phosphatase, active site [IPR016130] 0.6613192799639025 1.7723049706522995 0.0763439465754975 0.9862736469329748 0.1084887661862334 7 Q06124,P51452,O60942,Q8NCE2 4 +L-lactate dehydrogenase, active site [IPR018177] 0.5520740077588702 1.3250747817839486 0.1851463493970722 0.9999842130134065 0.2173457145096065 2 P00338 1 +Serine/threonine-protein kinase, active site [IPR008271] 0.5715168292762668 1.30747950425158 0.1910499113091086 0.99998933960601 0.2195041534189759 59 P36507,P49841,P68400,Q13523,O75116,P31751,Q00535,O14965,P78362,P17612,Q9NYV4,Q00534,Q9H2G2,Q15418,Q7KZI7,P19784,Q16513,O14976,P11802,Q96SB4,O15111,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q99570,P53350 30 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.4537459232471753 0.7542201563351937 0.4507170363356465 0.9999999999999912 0.4772298031789199 5 P49427 1 +Peptidase S9, serine active site [IPR002471] 0.3288570575947485 0.2808291331722057 0.7788414573918914 1.0 0.7935365792294742 2 P48147 1 +Cysteine peptidase, cysteine active site [IPR000169] 0.2987807311213846 0.1780108471168937 0.858714457029538 1.0 0.858714457029538 3 P17655 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f19d45b314c9a29ff041148a556c1406d26ed655 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP6", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "OXSM", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "VRK1", "WNK1", "YES1"], "leading_proteins": ["AKT2", "AURKA", "CAMK2G", "CAPN2", "CASP6", "CDC34", "CDK12", "CDK4", "CDK5", "CDK6", "CHEK2", "CHUK", "CLK3", "CSNK2A1", "CSNK2A2", "DUSP3", "GAK", "GSK3B", "LDHA", "MAP2K2", "MAPK1", "MARK2", "MTMR14", "NME1", "PIK3R4", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTPN11", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "SLK", "SRPK1", "SRPK2", "UBA1", "UBA2", "VRK1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6cc103c3aeab8f869136acd9de59a2c0271afc60 --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "IQ motif, EF-hand binding site [IPR000048]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4d11c79f9adf919041b04874eaa4f28064d4c2bf --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ff282476e8a7892c891efc5f9e696b0c6b1c9d150339d547ad125ce8532365c0 +size 185303 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7a67b7ee56098949aa21f34dc10a407e1f90753f --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "IQ motif, EF-hand binding site [IPR000048]", "1": "Protein kinase, ATP binding site [IPR017441]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5677a049113d24e99a29f8ce98fea45793415f67 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:689d9d299bb4f4a9a3bc6ef56d3946b13e3eb3117c6df5d3695b97d83439e7f6 +size 134787 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a5c40fad7b20724d90602b2d8bb9d38b8537e28c --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9944d826a0bb544aaa8291b5b5562bdba933a88f6dea2c624480eb96d2ba9355 +size 149566 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f9ba9c639a55333771f83c3fbb220cc9116049b2 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c374d21584d67a0fc86ed350c2b2bda66068adc428049e7f2cbe4984d2d79e3 +size 78889 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d5dbe138f572bb639a47e2d0b5e0acf560ec3bcc --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +IQ motif, EF-hand binding site [IPR000048] 7 11 1.9641721193186052 0.049510134916773 4.902912621359223 10.79368932038835 -0.2273048691062784 0.5134620963427197 2.787853554074696 2.339749173467172 1.002129759133213 0.3214407723554939 0.1755724648168266 0.3209553841799009 0.2541035375726295 0.0435237537141962 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a8136b4eaac3c10163184807d79fb1ad358ab643 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 5.032258064516129 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7cac054736e6fa2ab96e4dd77ac74bdfd1325017 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fba47428bf0d4dc13fe928efcde2b956ebfb4d93 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.7308266189197136 2.225910352486596 0.0260201867987768 0.5583801071568932 0.0733296173420074 2 P50579 1 +IQ motif, EF-hand binding site [IPR000048] 0.7125239743527818 1.9641721193186057 0.049510134916773 0.792808371994419 0.1180626294169202 11 O43795,O94832,P35580,P35579,Q92614,P46940,Q15386 7 +Beta tubulin, autoregulation binding site [IPR013838] 0.5536906486697772 1.2179901728783482 0.2232277071881654 0.9996027119450964 0.3008721270797012 7 P04350,Q13885,Q9BUF5 3 +Protein kinase, ATP binding site [IPR017441] 0.5305966794650098 0.96512253140751 0.3344834428081153 0.9999967044735356 0.4109330574622998 56 P36507,P49841,P68400,O75116,P31751,Q00535,O14965,P78362,P17612,Q9NYV4,Q00534,Q9H2G2,Q15418,Q7KZI7,P19784,Q16513,Q96SB4,O15111,Q16512,Q13555,Q13464,P28482,Q99986,P49761,P53350 25 +PPM-type phosphatase, divalent cation binding [IPR000222] 0.4882054344580557 0.9480161083037252 0.3431212537925143 0.999997801930017 0.4109330574622998 4 P49593,O15355,Q9H0C8 3 +Hexokinase, binding site [IPR019807] 0.4001790510295411 0.5666525199719206 0.5709502850120776 0.9999999999959474 0.6555355124212743 2 P52789 1 +Biotin-binding site [IPR001882] 0.3012839653627829 0.1734721036935777 0.8622803534663142 1.0 0.8910230319151913 4 P11498,Q13085,Q96RQ3 3 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8c7d69eb082b27660f0c491233857e498acc1b2a --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQSEC1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PPM1L", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["ACACA", "AKT2", "AURKA", "CAMK2G", "CDK12", "CDK5", "CDK6", "CHUK", "CLK3", "CSNK2A1", "CSNK2A2", "GSK3B", "HK2", "ILKAP", "IQGAP1", "MAP2K2", "MAPK1", "MARK2", "MCCC1", "METAP2", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1D", "PC", "PKN1", "PKN2", "PLK1", "PPM1F", "PPM1G", "PRKACA", "ROCK1", "ROCK2", "RPS6KA1", "SLK", "SRPK1", "SRPK2", "TUBB2A", "TUBB4A", "TUBB6", "UBE3C", "VRK1"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..09f148a809328bb205159bd83e36c1cbeb403b7d --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c4de52bd635573e1e2c7e74b8f18ef3681f228e0 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f559746f789c7aa448ddc5128420f20bf2f3d2ed2aa9a58ae33747f6fad8dcc +size 197517 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ef74ba513c5faad2b7fc4ad92a7ee42f80710a3d --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "2": "Ubiquitin specific protease, conserved site [IPR018200]", "3": "Cullin, conserved site [IPR016157]", "4": "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "5": "Kinesin motor domain, conserved site [IPR019821]", "6": "AMP-binding, conserved site [IPR020845]", "7": "Bromodomain, conserved site [IPR018359]", "8": "Zinc finger, PHD-type, conserved site [IPR019786]", "9": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..25f67a509c42289120c880592071e66697f08f12 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid 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sha256:6a27727ac3557dc476678f8858f8f0341a57c7d3e8eaa1efeadb12911bdfe418 +size 143090 diff --git a/interpro_conserved_site/basic/plot_8.png b/interpro_conserved_site/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..b3daba32d2e861cf0bac0ffb2c64641388e743d0 --- /dev/null +++ b/interpro_conserved_site/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:576af73593c3b10ec9c3350c58be21f6ffd792abc87af06f83a2e31f09ce95b4 +size 154930 diff --git a/interpro_conserved_site/basic/plot_9.png b/interpro_conserved_site/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c414ded1bb1b60b0e8f01e85ef22583a322ac450 --- /dev/null +++ b/interpro_conserved_site/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9c5eae2b4ac4f3a46f65b7cf88a33585dfc96e9b4af9d8b14d1e3b0fe70d7b63 +size 158100 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..761e211236a526c83d953449cfce57dbce45841f --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e81cec4c67a235c8270f29e6d6ff45a2eca1d4468af1f9475cf0542ff089dff +size 139802 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bea67644acb2aedf4c63177bbcfbbf3fbd0eabb4 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 5 7 2.428415899760516 0.0151649417818369 2.3592233009708736 5.065533980582524 -0.0414779785270424 0.5135274314368297 1.4687975990686668 1.3840549880732227 1.041360968799742 0.3265718594638703 0.0607401038440192 0.0066572828402184 8.971938182982207e-06 1.665940864684324e-05 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fd9a1bad36906aea686ceebda09e9ee955d076c3 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 279, + "title": "Average number of proteins per term", + "value": 2.824372759856631 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8cf3acb106c1c29267c5082d7f172524dacec0a4 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4ba24172f0a84c849b9f8b8fe7000d5c7ce31841 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,44 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Macrophage migration inhibitory factor, conserved site [IPR019829] 0.8737690241718874 2.8930903316517553 0.0038147156835786 0.6557340689631938 0.0149998265486966 2 P30046 1 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.8522829006266746 2.7960652192833404 0.0051728960376729 0.7647211277198352 0.0183394445911261 2 P15880 1 +Ras GTPase-activating protein, conserved site [IPR023152] 0.8565403990435811 2.794818295295859 0.0051928893286701 0.766036689229223 0.0183394445911261 3 P46940 1 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.8203521336914312 2.6497695035539595 0.0080546702225758 0.895268183772187 0.0257874624713309 2 P06737 1 +Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314] 0.7961802447030683 2.5373245219351173 0.011170335275684 0.9564593618628532 0.0311652354191583 2 Q8TEA1 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.7860340196956077 2.489685794871203 0.0127856071928937 0.9724067741688224 0.0342998500655516 2 P50570 1 +Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.7814925373134383 2.4462574016823524 0.0144347904688721 0.982693203296255 0.0376383788861246 3 Q6XZF7,Q9H8V3 2 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.7940880828875694 2.428415899760516 0.0151649417818369 0.985926031751877 0.0391760996030787 7 O00443,P42356,Q13535,Q13315,P78527 5 +Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.7233661593554184 2.189677273527157 0.0285476504240849 0.9996905436926176 0.0589984775431088 2 Q9UBT2 1 +DNA ligase, ATP-dependent, conserved site [IPR016059] 0.7264554192657929 2.181673169469412 0.0291336624664673 0.9997384921920508 0.0594936936047054 3 P18858 1 +Phosphofructokinase, conserved site [IPR015912] 0.7226106659490537 2.1629092648762085 0.0305481590431688 0.999825891139374 0.0608781169503151 3 P17858 1 +tRNA-dihydrouridine synthase, conserved site [IPR018517] 0.698299015219326 2.066930405390897 0.0387407122034602 0.9999836877758688 0.0745424738259682 2 Q6P1R4 1 +Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.6941211578633251 2.0463245180551017 0.0407244530021897 0.9999908335465962 0.0765227781853248 2 P09972 1 +Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.6938227394807515 2.044851074841573 0.0408695426020817 0.9999912123374964 0.0765227781853248 2 O60573 1 +GTP1/OBG, conserved site [IPR006074] 0.6893464637421588 2.022724061914973 0.0431016046771284 0.9999954126113596 0.0780100382350314 2 Q9Y295 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.6916008390981723 2.010267768575607 0.0444028562719376 0.9999968617958628 0.0788200476295484 3 P09429 1 +IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.6776119402985132 1.9406725941942815 0.0522980025930732 0.9999996899504736 0.0889703824601673 3 Q9P2T1,P20839 2 +Mrp, conserved site [IPR000808] 0.6746435904303525 1.9258481467480435 0.0541233376374425 0.9999998189375646 0.0904216239571645 3 Q9Y5Y2 1 +DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.7073727809028337 1.872531406285628 0.0611331210980918 0.9999999772740976 0.1009239099785067 16 Q14562,O60231,Q14839,Q7Z478,Q8IX18,Q12873,Q86WJ1,Q92620,Q6P158,P18074,Q9UNY4 11 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.6571172784243453 1.8620446659348515 0.0625967945994796 0.9999999852946572 0.1021316122412562 2 P63167 1 +Profilin conserved site [IPR027310] 0.607579826917332 1.6108519191081117 0.1072120017443478 0.999999999999982 0.1621155241565494 2 P07737 1 +Ubiquitin specific protease, conserved site [IPR018200] 0.6569059169885605 1.609550797830045 0.1074959568779987 0.9999999999999832 0.1621155241565494 16 Q70CQ2,Q9UPT9,P40818,Q93008,Q96RU2 5 +Mini-chromosome maintenance, conserved site [IPR018525] 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.2156142249821201 6 P33993,P33991,P33992 3 +Rel homology domain, conserved site [IPR030492] 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.2205424054026356 2 Q00653 1 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.5669432960731753 1.376977007062654 0.1685193567366631 1.0 0.226042791007351 3 Q9BXS5 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.5850516916003337 1.3608392355946868 0.1735644996744167 1.0 0.2305928352817251 8 P20618,P49721,P49720,P28072 4 +Cullin, conserved site [IPR016157] 0.5748431431132425 1.347784549143037 0.1777276888284671 1.0 0.2350048586878783 6 Q13616,Q93034,Q13620,Q13617,Q13618 5 +Ribosomal protein S2, conserved site [IPR018130] 0.5553566099671647 1.342044192109222 0.1795816672627257 1.0 0.2363362507844362 2 P08865 1 +Tubulin, conserved site [IPR017975] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2743635696277451 7 P04350,Q13885,Q9BUF5 3 +Oxysterol-binding protein, conserved site [IPR018494] 0.5491779532515481 1.2150684642992582 0.2243399801128189 1.0 0.2745212914538442 6 Q9BZF3 1 +Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.5557338856001716 1.1062813649354573 0.2686047550300945 1.0 0.3162055976936556 14 P47897,P07814,P41252,P23381,Q9P2J5,P26640 6 +AT hook, DNA-binding motif [IPR017956] 0.503625590373838 1.0503490225994978 0.2935576740304939 1.0 0.3370476998127893 3 P17096 1 +Kinesin motor domain, conserved site [IPR019821] 0.5046108492695173 0.8447385604056377 0.398256824916225 1.0 0.4462395749061317 14 Q15058,Q9BW19,Q96Q89,Q9Y496,O00139,Q99661,O60333 7 +Actin/actin-like conserved site [IPR020902] 0.4211940298507544 0.6419292703829347 0.5209191081889026 1.0 0.5721906739555269 3 P61163,P61160 2 +Sulfatase, conserved site [IPR024607] 0.4037600716204089 0.5829388314397551 0.5599344786841418 1.0 0.6126341943250022 2 P15289 1 +Chromo domain, conserved site [IPR023779] 0.4107228413739149 0.5526946313018807 0.5804725302120524 1.0 0.630162785716586 5 O14646 1 +AMP-binding, conserved site [IPR020845] 0.379372197309425 0.3718830394052872 0.7099799335511643 1.0 0.7618630825414416 8 O14975,Q6P1M0,P33121,Q4G176,O95573,Q96CM8,Q86V21 7 +Ubiquitin conserved site [IPR019954] 0.357014925373138 0.3659190383422156 0.7144254895884747 1.0 0.7628502093185238 3 P46379,O14562 2 +Ribosomal S11, conserved site [IPR018102] 0.3270665472993151 0.2748316300723444 0.7834455961840823 1.0 0.8248351748504111 2 P62263 1 +Bromodomain, conserved site [IPR018359] 0.3571206852935066 0.2564049488381634 0.7976381669398629 1.0 0.8334870733191826 11 Q12830,P25440,Q9UIG0,P51532,Q9UIF9 5 +Zinc finger, PHD-type, conserved site [IPR019786] 0.2793243575729205 0.0550084342571624 0.9561317444031112 1.0 0.972662486746963 18 Q12830,Q9UPP1,Q14839,Q12873,P29375 5 +Zinc finger, RING-type, conserved site [IPR017907] 0.2695283728118322 0.044217896584255 0.9647307165939472 1.0 0.9752169200351856 19 Q96EP0,Q14527,Q14258 3 +ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.2529777978113436 0.0309649676495106 0.9752974780330816 1.0 0.982339337080252 21 Q9UHI6,P26196,Q7L014,Q14240,Q9GZR7,Q96GQ7,Q8NHQ9 7 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e78cb1d6ad4cce1ae9c904d4393ad67402aa233e --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Carbonic anhydrase, alpha-class, conserved site [IPR018338]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARHGEF7", "ARIH2", "ARRB1", "ARSA", "ATAD1", "ATAD2", "ATAD2B", "ATM", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CA8", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS1L", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPR2", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXA10", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "IQGAP1", "IQGAP2", "ISCA2", "IVD", "KATNA1", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LIG4", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFM", "NES", "NF1", "NFKB2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NSUN6", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RNF169", "RNF2", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SFN", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE4", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", 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a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..422bd3c71c320a9bd492768f7e06f68b3fab1394 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,17 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +PIK-related kinase, FAT [IPR003151] 4 5 2.796203174717384 0.00517068832692 1.672330097087379 3.1407766990291264 -0.2139101026296354 0.5194295127936944 0.9838064612370848 0.8974545333648188 1.0476903847911485 0.3181207592603047 0.0238038053541035 0.0471521402185075 1.6763230163867931e-06 2.6995663558697725e-07 +FATC domain [IPR003152] 4 5 2.796203174717384 0.00517068832692 1.7524271844660195 3.3398058252427183 -0.2211924578113137 0.5142924408811651 1.0459672589683773 1.0888080064536276 1.051311965823244 0.3188390843049937 0.028497516818446 0.0563150378970086 4.932723369202767e-06 1.554575126715766e-06 +PIK-related kinase [IPR014009] 4 5 2.796203174717384 0.00517068832692 1.7524271844660195 3.3398058252427183 -0.2211924578113137 0.5142924408811651 1.0459672589683773 1.0888080064536276 1.051311965823244 0.3188390843049937 0.028497516818446 0.0563150378970086 4.932723369202767e-06 1.554575126715766e-06 +F-box domain [IPR001810] 2 5 2.626658514196889 0.0086227820155255 1.8442822384428224 3.929440389294404 -0.3231925043100016 0.5120491320380128 1.35448615988663 1.3244415536097904 0.9015450171505716 0.2951220788963267 0.2030241760545403 0.0748026769138462 0.3174825468726979 0.4036293153292029 +KOW [IPR005824] 3 5 2.541768081630134 0.0110293329353363 2.9393203883495147 5.349514563106796 -0.3288066047063325 0.4912799084151893 1.4593879300449948 0.8120301522939392 0.9166573511426293 0.2932365525740842 1.0 1.0 1.0 0.0001735559058557 +Peptidase C14, p20 domain [IPR001309] 2 5 2.4874236498899984 0.0128672069430639 1.0429042904290429 2.254125412541254 -0.1822739771754456 0.4061856906844451 0.8796230895210494 1.190490848145931 1.5263000234628414 0.3357787389369007 1.0 1.0 0.0007272762906085 0.0053637976870067 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 1 5 2.4488388371750647 0.0143317558486661 1.9514563106796117 4.538834951456311 0.0568915518268352 0.6178806106025803 1.3821233191906093 0.9404329729664274 0.8120485047765617 0.3064331966816168 0.0470522829573702 0.0921025797166938 0.0233125205204954 0.0823369674942117 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 6 9 2.369325962142017 0.0178205399094071 2.878640776699029 6.735436893203883 -0.1009242226376213 0.5398631989476717 1.7790119700005456 1.6967720791950751 0.9747821830158722 0.3245983921794569 0.0742352733278267 0.0100519320580488 1.2724933964024938e-06 4.8839176890034255e-06 +TOG domain [IPR034085] 5 6 2.342383929729876 0.01916099288754 3.325242718446602 6.601941747572815 -0.0987661754241745 0.549371431974734 1.7504628207188018 0.489497579260409 0.9030559512459012 0.3068564129993026 1.0 0.0832836732680532 0.1988473022417859 0.0077568745967145 +HECT domain [IPR000569] 4 10 2.307806896040579 0.0210098792090507 3.5364077669902914 8.95631067961165 -0.082655155531572 0.5172769027958292 2.244980314039549 2.0498718834184824 0.9922663464789628 0.3114818745947644 0.0068317681715133 0.0255840399150975 0.0003539240376489 0.0075753503172145 +Cyclin-like [IPR013763] 3 5 2.2567765969868367 0.0240220378052291 1.5407407407407407 3.4098765432098768 0.0739811189971918 0.5422801432539582 1.1743953293396394 1.6177720496137604 1.0716835988943594 0.3150272661941172 0.1305522111527444 0.2445730022705269 0.1562190614045352 0.1659016353191164 +Myosin, N-terminal, SH3-like [IPR004009] 3 5 2.237874308157222 0.0252292528828856 2.412621359223301 4.684466019417476 -0.1448549248535419 0.5229359227697599 1.417517288923896 0.97664546553505 0.9807639625700678 0.3174032539640412 1.0 1.0 1.0 0.0823369674942117 +Tyrosine-specific protein phosphatases domain [IPR000387] 6 8 2.15092271399219 0.0314823003879805 2.7063106796116503 7.213592233009709 -0.3132851926661954 0.5285529785740709 1.7372724354944058 2.1390973753662776 0.9021701078616204 0.297631084722613 1.0 0.3777229935777695 0.3354134477865137 0.0888810791636133 +Importin-beta, N-terminal domain [IPR001494] 11 13 2.142280780388436 0.0321708944842114 6.385922330097087 13.28883495145631 0.1695856896111973 0.5104356360219653 3.297409379395681 0.8134617396566306 1.1027535719761996 0.3475482514742156 0.0786913117950012 0.1515272625734178 0.3422564852890665 0.0001016217979366 +Myosin head, motor domain [IPR001609] 5 8 2.026987590455855 0.0426636817938452 4.390776699029126 8.03883495145631 -0.430616208806789 0.4683474380026073 2.071585945303128 1.3360013523704524 1.027601418852351 0.3224719398001398 1.0 1.0 1.0 0.0892170338783466 +SNF2, N-terminal [IPR000330] 13 18 1.993487100957407 0.0462081346183014 6.303398058252427 14.475728155339803 -0.5651620597123135 0.4591559356456904 3.369291375872709 3.0188555029116086 0.984948378295502 0.3251280211427139 1.0 0.0376249374527164 0.0001038396922648 1.482058094111503e-05 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dffa4607d4a90394f621e94d5562716df62ae1b0 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 2725, + "title": "Average number of proteins per term", + "value": 2.228623853211009 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a1cc1797b5048ae425aa34fc87b59cc3718b308c --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bcb7a2315512e3a77bb74c5346fc84471c1d68bd --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,346 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Condensin complex subunit 1, C-terminal [IPR032682] 0.9510593852581296 3.232986633349474 0.0012250329443372 0.9645722956542492 0.0151061675645344 2 P42695 1 +Cold-shock (CSD) domain [IPR019844] 0.9192166166380789 3.0753355194675924 0.0021026586859593 0.9967716277805558 0.0167537053678692 3 P67809 1 +C2 DOCK-type domain [IPR027007] 0.9003282602208236 3.011477694748019 0.0025997950235718 0.9991696526737216 0.0178719843769408 2 Q14185 1 +DOCKER domain [IPR027357] 0.9003282602208236 3.011477694748019 0.0025997950235718 0.9991696526737216 0.0178719843769408 2 Q14185 1 +Sec7, C-terminal [IPR015403] 0.8857057594747769 2.946507856098296 0.0032138425512258 0.999844959493865 0.0185392959957585 2 Q9Y6D5 1 +Mon2, dimerisation and cyclophilin-binding domain [IPR032629] 0.8857057594747769 2.946507856098296 0.0032138425512258 0.999844959493865 0.0185392959957585 2 Q9Y6D5 1 +Domain of unknown function DUF3517 [IPR021905] 0.8860552134585163 2.9280903086081085 0.0034105096917538 0.9999094422743814 0.0186745136196415 3 Q70CQ2 1 +Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.8859701492537342 2.9277092352463425 0.0034146921620967 0.9999104720165704 0.0186745136196415 3 Q92538,Q9Y6D5 2 +TATA-binding protein interacting (TIP20) [IPR013932] 0.8761563712324649 2.9038014046013743 0.0036866192790228 0.9999574402306272 0.0191353095911183 2 O75155 1 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.8680990749030086 2.8675960417403994 0.004136032490805 0.9999875533739628 0.0201716024422636 2 Q9UBF2 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.8680990749030086 2.8675960417403994 0.004136032490805 0.9999875533739628 0.0201716024422636 2 Q9UBF2 1 +Dual specificity phosphatase, catalytic domain [IPR000340] 0.8739922364884956 2.854429362103554 0.0043114218401991 0.9999922979511864 0.0205604058431984 4 O60942,Q9UNI6,Q99956 3 +Dual specificity protein phosphatase domain [IPR020422] 0.8739922364884956 2.854429362103554 0.0043114218401991 0.9999922979511864 0.0205604058431984 4 O60942,Q9UNI6,Q99956 3 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9999958511473857 0.0209388373321269 3 P20585 1 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9999958511473857 0.0209388373321269 3 P20585 1 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9999958511473857 0.0209388373321269 3 P20585 1 +DNA mismatch repair protein MutS, core [IPR007696] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9999958511473857 0.0209388373321269 3 P20585 1 +Serine/threonine-protein kinase N, C2 domain [IPR037784] 0.8570575947478358 2.8177240904489955 0.0048365351369787 0.9999981706193416 0.0214330161167317 2 Q16513 1 +Serine/threonine-protein kinase N, first HR1 domain [IPR037313] 0.8570575947478358 2.8177240904489955 0.0048365351369787 0.9999981706193416 0.0214330161167317 2 Q16513 1 +Nucleoside diphosphate kinase-like domain [IPR034907] 0.8567591763652582 2.816372053583634 0.0048569384395626 0.9999982700237402 0.0214856448828057 2 P15531 1 +CLASP N-terminal domain [IPR024395] 0.8564607579826891 2.8150197979105585 0.004877422903623 0.9999983643921556 0.0215084077470553 2 Q7Z460 1 +Pre-PUA domain [IPR041366] 0.8561623396001108 2.8136673233858542 0.0048979888272031 0.9999984539595704 0.0215274508937558 2 Q9ULC4 1 +Methylglyoxal synthase-like domain [IPR011607] 0.854968666069828 2.808255235897178 0.0049810731116037 0.9999987685793026 0.0216763416655936 2 P27708 1 +OTU domain [IPR003323] 0.8594029850746304 2.8078369494597757 0.0049875472382852 0.9999987902204264 0.0216763416655936 3 Q6GQQ9,Q01804 2 +PIK-related kinase, FAT [IPR003151] 0.8652927120669004 2.796203174717384 0.00517068832692 0.999999267409955 0.022014249404157 5 Q9Y4A5,Q13535,P78527,Q13315 4 +FATC domain [IPR003152] 0.8652927120669004 2.796203174717384 0.00517068832692 0.999999267409955 0.022014249404157 5 Q9Y4A5,Q13535,P78527,Q13315 4 +PIK-related kinase [IPR014009] 0.8652927120669004 2.796203174717384 0.00517068832692 0.999999267409955 0.022014249404157 5 Q9Y4A5,Q13535,P78527,Q13315 4 +Ribosomal protein S5, C-terminal [IPR005324] 0.8522829006266746 2.7960652192833404 0.0051728960376729 0.9999992718267692 0.022014249404157 2 P15880 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.8522829006266746 2.7960652192833404 0.0051728960376729 0.9999992718267692 0.022014249404157 2 P15880 1 +Inositol polyphosphate-related phosphatase [IPR000300] 0.8454192778275096 2.764832123207259 0.0056952097449562 0.99999982593 0.0230944145163778 2 Q01968 1 +CHD, N-terminal [IPR012958] 0.8418382572366412 2.74849034125845 0.0059870398842125 0.9999999217782288 0.0234743650136391 2 Q14839 1 +CHD, C-terminal 2 [IPR012957] 0.8418382572366412 2.74849034125845 0.0059870398842125 0.9999999217782288 0.0234743650136391 2 Q14839 1 +CHD subfamily II, SANT-like domain [IPR009462] 0.8418382572366412 2.74849034125845 0.0059870398842125 0.9999999217782288 0.0234743650136391 2 Q14839 1 +Domain of unknown function DUF1087 [IPR009463] 0.8418382572366412 2.74849034125845 0.0059870398842125 0.9999999217782288 0.0234743650136391 2 Q14839 1 +Methyltransferase domain [IPR025714] 0.8455407173478664 2.74460601974351 0.0060583581810722 0.9999999356698708 0.023634842858063 3 Q7L2J0 1 +BRK domain [IPR006576] 0.8432835820895556 2.734265603585516 0.0062519590643606 0.9999999621663718 0.0239951950005389 3 Q9P2D1,Q9HCK8 2 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.841829786319154 2.727598793112745 0.006379715052978 0.999999973348364 0.0240870380896902 3 Q07864 1 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.841829786319154 2.727598793112745 0.006379715052978 0.999999973348364 0.0240870380896902 3 Q07864 1 +Exportin-1/Importin-beta-like [IPR013598] 0.8456255598686058 2.724983073346092 0.0064304783675135 0.999999976812142 0.024136437398725 4 O14980,Q9Y5L0,Q9HAV4 3 +APC10/DOC domain [IPR004939] 0.838767264903356 2.693390495293382 0.0070729375290496 0.9999999960210144 0.0256406526274021 4 O75592,Q14999 2 +Cyclin, C-terminal domain [IPR004367] 0.8339802926246533 2.6712706509691264 0.0075564691448093 0.9999999989448382 0.0261311908878241 4 O75909,O95067,P14635 3 +Cyclin, N-terminal [IPR006671] 0.8339802926246531 2.6712706509691264 0.0075564691448093 0.9999999989448382 0.0261311908878241 4 O75909,O95067,P14635 3 +ABC-transporter extension domain [IPR032781] 0.8248284094300186 2.67043142848405 0.007575384273077 0.9999999989982408 0.0261633994222241 2 Q9UG63 1 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.8188600417785693 2.642871032977302 0.0082206340868946 0.99999999982976 0.0274524851553774 2 P07814 1 +Ribosomal RNA methyltransferase FtsJ domain [IPR002877] 0.8232835820895564 2.6420898316286063 0.0082396198674541 0.999999999838413 0.0274740751337607 3 Q8N1G2,Q9UET6 2 +ROCK, Rho binding domain [IPR015008] 0.8173679498657005 2.6359669751594077 0.0083897896469236 0.999999999893046 0.02774536017945 2 O75116 1 +F-box domain [IPR001810] 0.8285542192328827 2.6266585141968894 0.0086227820155255 0.9999999999436237 0.0281557824521336 5 Q14241,Q9Y3I1 2 +DMAP1-binding domain [IPR010506] 0.8128916741271149 2.6152212435195006 0.0089169674719125 0.9999999999748892 0.0287559010188894 2 P26358 1 +PurM-like, C-terminal domain [IPR010918] 0.8159620777991429 2.608097593597647 0.0091046992061381 0.9999999999850144 0.0290191052385745 3 O15067 1 +HR1 rho-binding domain [IPR011072] 0.8178560764407203 2.5963456450133515 0.0094221229219093 0.999999999993741 0.0295575709758456 4 Q16512,O75116,Q16513 3 +Gamma tubulin complex component, C-terminal [IPR040457] 0.803939122649951 2.573578480635401 0.010065281646816 0.9999999999989336 0.03061148715131 2 Q96CW5 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.803939122649951 2.573578480635401 0.010065281646816 0.9999999999989336 0.03061148715131 2 Q96CW5 1 +Cold shock domain [IPR011129] 0.8115781137545517 2.566998884629866 0.0102582942385929 0.9999999999993732 0.0310598353335174 4 P67809 1 +Cold-shock protein, DNA-binding [IPR002059] 0.8115781137545517 2.566998884629866 0.0102582942385929 0.9999999999993732 0.0310598353335174 4 P67809 1 +KOW [IPR005824] 0.8104247249687031 2.541768081630134 0.0110293329353363 0.9999999999999252 0.0324918186473422 5 P61353,P62701,Q92917 3 +Ribosomal protein L18e/L15P [IPR021131] 0.7967977821808943 2.51848635775526 0.0117860449181002 0.9999999999999908 0.0340222165273549 3 P46776 1 +Exportin-2, central domain [IPR013713] 0.7967164179104491 2.5181039380494306 0.0117988497445438 0.999999999999991 0.0340231381522559 3 O15397,O95373 2 +EH domain-containing protein, N-terminal [IPR031692] 0.789913458669047 2.5079313713017544 0.0121440250915358 0.9999999999999966 0.0343662187435939 2 Q9H223 1 +Domain of unknown function DUF5600 [IPR040990] 0.789913458669047 2.5079313713017544 0.0121440250915358 0.9999999999999966 0.0343662187435939 2 Q9H223 1 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058] 0.7944437210934608 2.5074153280259246 0.0121617715597377 0.9999999999999968 0.0343662187435939 3 P07814 1 +Sec7 domain [IPR000904] 0.7921078842338598 2.49641623971699 0.012545529324365 0.9999999999999988 0.0351159557349997 3 Q9Y6D5 1 +Amine oxidase [IPR002937] 0.7912746653211817 2.4924894240782467 0.0126851108220882 0.9999999999999992 0.035236418950245 3 Q8NB78 1 +Dynamin GTPase effector [IPR003130] 0.7860340196956077 2.489685794871203 0.0127856071928937 0.9999999999999994 0.035263946964206 2 P50570 1 +Dynamin stalk domain [IPR000375] 0.7860340196956077 2.489685794871203 0.0127856071928937 0.9999999999999994 0.035263946964206 2 P50570 1 +GTPase effector domain [IPR020850] 0.7860340196956077 2.489685794871203 0.0127856071928937 0.9999999999999994 0.035263946964206 2 P50570 1 +Peptidase C14, p20 domain [IPR001309] 0.7989090461472421 2.4874236498899984 0.0128672069430639 0.9999999999999996 0.0353815730775472 5 P42574,P55212 2 +SUN domain [IPR012919] 0.786039155285832 2.467775432395136 0.013595558221386 1.0 0.0368269345460009 3 Q9UH99 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.7907748606288872 2.4488388371750647 0.0143317558486661 1.0 0.0381759869869163 5 P38935 1 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.780010127074519 2.439230278345425 0.0147185856645222 1.0 0.0389777900250952 3 O00443 1 +Domain of unknown function DUF1747 [IPR013719] 0.7737988660101431 2.431892294526774 0.0150201730235854 1.0 0.0396608250865023 2 Q08945 1 +TRASH domain [IPR011017] 0.7738162371101645 2.4098093812883707 0.0159608571885347 1.0 0.0411090130801108 3 P83731 1 +Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.7672336615935444 2.4007247524351376 0.0163626390863487 1.0 0.0420246856836006 2 Q9Y237 1 +ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284] 0.7666368248284048 2.397885924553535 0.0164899998501353 1.0 0.042272106859472 2 P46063 1 +RQC domain [IPR018982] 0.7666368248284048 2.397885924553535 0.0164899998501353 1.0 0.042272106859472 2 P46063 1 +BAT2, N-terminal [IPR009738] 0.7699759969531133 2.3915198653320218 0.0167787759293234 1.0 0.0427709676402304 3 P48634 1 +Exonuclease, RNase T/DNA polymerase III [IPR013520] 0.7714154003323062 2.3769294393063123 0.0174574272270437 1.0 0.0440884978625526 4 Q9GZR2 1 +Xrn1, helical domain [IPR041412] 0.7615637123246667 2.3737194673307163 0.0176099242381955 1.0 0.0441463142125876 2 Q8IZH2 1 +Putative 5-3 exonuclease [IPR004859] 0.7615637123246667 2.3737194673307163 0.0176099242381955 1.0 0.0441463142125876 2 Q8IZH2 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.7883138973898095 2.3693259621420175 0.0178205399094071 1.0 0.0443374326285298 9 O00443,P42356,Q13535,Q13315,Q9Y4A5,P78527 6 +Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034] 0.7594747836466622 2.3637496386053987 0.0180910336617878 1.0 0.0446540459496122 2 Q2NL82 1 +Bms1/Tsr1-type G domain [IPR030387] 0.7594747836466622 2.3637496386053987 0.0180910336617878 1.0 0.0446540459496122 2 Q2NL82 1 +AARP2CN [IPR012948] 0.7594747836466622 2.3637496386053987 0.0180910336617878 1.0 0.0446540459496122 2 Q2NL82 1 +TOG domain [IPR034085] 0.7726322079474114 2.342383929729876 0.01916099288754 1.0 0.0462887461157327 6 Q14008,Q86Y56,Q7Z460,Q8TEX9,Q92616 5 +Putative RNA methylase domain [IPR000241] 0.7532079976126418 2.3337739483644233 0.0196075616154507 1.0 0.04720815550398 2 Q7Z4G4 1 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.7514174873172078 2.3251912431651944 0.0200617363879911 1.0 0.0479007286262761 2 Q9UID3 1 +HECT domain [IPR000569] 0.7786741455171677 2.307806896040579 0.0210098792090507 1.0 0.0496978479554368 10 O95071,Q9UII4,Q15386,Q7Z6Z7 4 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.7548521946849711 2.297373612911015 0.0215974657240558 1.0 0.0506481016334356 4 P46087,Q8TEA1,Q96P11 3 +Zinc finger, MYND-type [IPR002893] 0.7442554461354808 2.290779581403478 0.0219761651637355 1.0 0.0514918745238 2 Q9GZT9 1 +Ras GTPase-activating domain [IPR001936] 0.7527713728560361 2.287330998491067 0.0221765104608966 1.0 0.0518595351283308 4 P46940 1 +Peptidase C14, caspase non-catalytic subunit p10 [IPR002138] 0.7513871449439907 2.2806444125520073 0.0225694969698586 1.0 0.0524760061799188 4 P55212 1 +Peptidase C14A, caspase catalytic domain [IPR015917] 0.7513871449439907 2.2806444125520073 0.0225694969698586 1.0 0.0524760061799188 4 P55212 1 +Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099] 0.7450746268656739 2.272027724057395 0.0230848358791448 1.0 0.0532201165572502 3 Q14558,P11908 2 +Anticodon-binding [IPR004154] 0.7487590773450472 2.2679363865060496 0.0233330841911607 1.0 0.053477252354538 4 P07814 1 +Cyclin-like [IPR013763] 0.7507871783358013 2.2567765969868367 0.0240220378052291 1.0 0.0545955404664299 5 O75909,O95067,P14635 3 +SGNH hydrolase-type esterase domain [IPR013830] 0.7356013130408694 2.2490267197291423 0.0245107961524635 1.0 0.0552913241022046 2 Q2TAA2 1 +Myosin, N-terminal, SH3-like [IPR004009] 0.7468953473392271 2.237874308157222 0.0252292528828856 1.0 0.0558167876348951 5 Q9UM54,P35579,Q92614 3 +GNAT domain [IPR000182] 0.7354106116788219 2.225237437803345 0.0260653028321895 1.0 0.0567651279650381 3 Q9GZZ1 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.7305282005371516 2.2244636892985152 0.026117262906526 1.0 0.0567993147807529 2 O43924 1 +Myotubularin-like phosphatase domain [IPR010569] 0.7343283582089616 2.219983095872216 0.0264199151140394 1.0 0.0572291483988532 3 O95248,Q13614 2 +Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.7290361086242924 2.2172270431865853 0.0266075804802961 1.0 0.0574529768691021 2 O94776 1 +Myosin tail [IPR002928] 0.7364689063297268 2.2082819661247823 0.0272246236565933 1.0 0.0579812372192023 4 P35579,Q92614 2 +Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164] 0.7269471799462828 2.207086423885334 0.0273080220665518 1.0 0.0580455227233648 2 O94973 1 +DNA ligase, ATP-dependent, C-terminal [IPR012309] 0.7264554192657929 2.181673169469412 0.0291336624664673 1.0 0.0603623466869475 3 P18858 1 +DNA ligase, ATP-dependent, N-terminal [IPR012308] 0.7264554192657929 2.181673169469412 0.0291336624664673 1.0 0.0603623466869475 3 P18858 1 +DNA ligase, ATP-dependent, central [IPR012310] 0.7264554192657929 2.181673169469412 0.0291336624664673 1.0 0.0603623466869475 3 P18858 1 +Peptidase S9A, N-terminal domain [IPR023302] 0.7203819755296925 2.175145365951279 0.0296192247789299 1.0 0.0608690705298523 2 Q4J6C6 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.7232794341488548 2.16617571011806 0.0302977625119433 1.0 0.061768758666149 3 Q9Y666 1 +SLC12A transporter, C-terminal [IPR018491] 0.7232794341488548 2.16617571011806 0.0302977625119433 1.0 0.061768758666149 3 Q9Y666 1 +Phosphofructokinase domain [IPR000023] 0.7226106659490537 2.1629092648762085 0.0305481590431688 1.0 0.0622150473786511 3 P17858 1 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.7404060276751346 2.15092271399219 0.0314823003879805 1.0 0.063190539517664 8 Q06124,O60942,P51452,Q99956,Q13614,Q9UNI6 6 +Importin-beta, N-terminal domain [IPR001494] 0.7533666795193318 2.1422807803884356 0.0321708944842114 1.0 0.0641677036452747 13 O14980,Q9HAV4,O43592,Q96P70,P55060,O15397,Q92973,Q9UIA9,Q9UI26,Q8TEX9,O95373 11 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.713219934347958 2.1401791382287576 0.0323402924437141 1.0 0.0644205386762581 2 Q96CX2 1 +Kinesin-associated [IPR032405] 0.7138672650498239 2.1201041154650526 0.0339972659765521 1.0 0.0665782523587008 3 O60333 1 +Peptidase M16, middle/third domain [IPR032632] 0.7087436586093698 2.1182613286870624 0.0341529417851069 1.0 0.0668103132551446 2 O43847 1 +Glutamine amidotransferase [IPR017926] 0.7077611940298543 2.090101126677883 0.036608716499829 1.0 0.0701045344076135 3 P17812,P27708 2 +DUS-like, FMN-binding domain [IPR035587] 0.698299015219326 2.066930405390897 0.0387407122034602 1.0 0.0728977121075458 2 Q6P1R4 1 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.6977021784541932 2.0639892636701545 0.0390187343532084 1.0 0.0733190306527801 2 O15344 1 +GH15-like domain [IPR011613] 0.6920322291853185 2.0360059691053007 0.041749755883627 1.0 0.0772881010753286 2 Q93100 1 +Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583] 0.6920322291853185 2.0360059691053007 0.041749755883627 1.0 0.0772881010753286 2 Q93100 1 +Myosin head, motor domain [IPR001609] 0.7154383762617841 2.026987590455855 0.0426636817938452 1.0 0.0785048691738351 8 Q9UM54,O94832,P35580,P35579,Q92614 5 +GTP binding protein, second domain [IPR031662] 0.6893464637421588 2.022724061914973 0.0431016046771284 1.0 0.0791275204319441 2 Q9Y295 1 +SNF2, N-terminal [IPR000330] 0.7346973471976695 1.993487100957407 0.0462081346183014 1.0 0.0824570030911478 18 Q9NRZ9,O14981,O14646,Q96L91,Q14839,P51532,Q9H4L7,Q12873,Q86WJ1,Q9P2D1,Q14527,Q9UNY4,Q9HCK8 13 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.6806923306475665 1.9798115353986976 0.047724709701477 1.0 0.084393143372177 2 O15027 1 +Diaphanous autoregulatory (DAD) domain [IPR014767] 0.6789018203521313 1.9709113273997452 0.0487340192487582 1.0 0.085954823594088 2 O60610 1 +Formin, FH3 domain [IPR010472] 0.6791044776119446 1.9481191511898024 0.0514007077802527 1.0 0.0896715292581233 3 O60610,Q27J81 2 +Formin, GTPase-binding domain [IPR010473] 0.6791044776119446 1.9481191511898024 0.0514007077802527 1.0 0.0896715292581233 3 O60610,Q27J81 2 +GHMP kinase N-terminal domain [IPR006204] 0.6732318710832582 1.9426787674905848 0.0520549832014971 1.0 0.0905454710074496 2 P51570 1 +IMP dehydrogenase/GMP reductase [IPR001093] 0.6776119402985132 1.9406725941942815 0.0522980025930732 1.0 0.0907142311051079 3 Q9P2T1,P20839 2 +CAP Gly-rich domain [IPR000938] 0.6768672472275434 1.9369553133420736 0.0527508060622583 1.0 0.0913833099298499 3 Q99426 1 +Gelsolin-like domain [IPR007123] 0.6855824615165006 1.935343987312146 0.0529480978818797 1.0 0.0916086137956331 5 Q13045,O95486,Q15436 3 +Poly(ADP-ribose) polymerase, regulatory domain [IPR004102] 0.6699492688749487 1.9263001798486663 0.0540669029927352 1.0 0.0932347925967437 2 P09874 1 +WGR domain [IPR008893] 0.6699492688749487 1.9263001798486663 0.0540669029927352 1.0 0.0932347925967437 2 P09874 1 +Formin, FH2 domain [IPR015425] 0.6793072558972804 1.9260887988304407 0.0540932870075052 1.0 0.0932347925967437 4 Q9Y613,O60610,Q27J81 3 +Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768] 0.6793072558972804 1.9260887988304407 0.0540932870075052 1.0 0.0932347925967437 4 Q9Y613,O60610,Q27J81 3 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.6696508504923881 1.9248100125153569 0.0542531309277538 1.0 0.0934511894931284 2 Q9NVE7 1 +Domain of unknown function DUF1605 [IPR011709] 0.7093206203581256 1.9195081438899413 0.0549200566313268 1.0 0.0941832311644843 13 O60231,Q14147,Q8IY37,Q7Z478,Q8IX18,Q92620,Q6P158,Q9H6S0 8 +Helicase-associated domain [IPR007502] 0.7093206203581256 1.9195081438899413 0.0549200566313268 1.0 0.0941832311644843 13 O60231,Q14147,Q8IY37,Q7Z478,Q8IX18,Q92620,Q6P158,Q9H6S0 8 +Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314] 0.6865690572886487 1.9189506187825305 0.0549905836239799 1.0 0.0942311386942664 6 P07814 1 +Poly(ADP-ribose) polymerase, catalytic domain [IPR012317] 0.670149253731348 1.9033655705822623 0.0569928602905012 1.0 0.0965230231768898 3 Q7Z2W4,P09874 2 +La protein, xRRM domain [IPR014886] 0.6639809012235011 1.896459033767968 0.0578993721044591 1.0 0.0974842773257843 2 Q4G0J3 1 +Calpain subdomain III [IPR033883] 0.6636824828409351 1.894964900630568 0.0580970518814949 1.0 0.0974842773257843 2 P17655 1 +Peptidase C2, calpain, domain III [IPR022683] 0.6636824828409351 1.894964900630568 0.0580970518814949 1.0 0.0974842773257843 2 P17655 1 +Peptidase C2, calpain, large subunit, domain III [IPR022682] 0.6636824828409351 1.894964900630568 0.0580970518814949 1.0 0.0974842773257843 2 P17655 1 +Peptidase C2, calpain, catalytic domain [IPR001300] 0.6636824828409351 1.894964900630568 0.0580970518814949 1.0 0.0974842773257843 2 P17655 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.6676358825149804 1.890773353421313 0.0586546056694254 1.0 0.0983166886380446 3 Q06210 1 +Mad3/Bub1 homology region 1 [IPR013212] 0.6627872276932245 1.8904813242438077 0.0586936160004678 1.0 0.0983166886380446 2 O43683 1 +Class I myosin tail homology domain [IPR010926] 0.6661973934451003 1.8835602328841712 0.0596244852218283 1.0 0.0994958494975397 3 O94832 1 +Class I myosin, motor domain [IPR036072] 0.6661973934451003 1.8835602328841712 0.0596244852218283 1.0 0.0994958494975397 3 O94832 1 +Sec23/Sec24 beta-sandwich [IPR012990] 0.6665892627869254 1.8622960327112277 0.0625613743887463 1.0 0.1029467060442836 4 O95486,Q15436 2 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.6665892627869254 1.8622960327112277 0.0625613743887463 1.0 0.1029467060442836 4 O95486,Q15436 2 +Sec23/Sec24, trunk domain [IPR006896] 0.6665892627869254 1.8622960327112277 0.0625613743887463 1.0 0.1029467060442836 4 O95486,Q15436 2 +Sec23/Sec24, helical domain [IPR006900] 0.6665892627869254 1.8622960327112277 0.0625613743887463 1.0 0.1029467060442836 4 O95486,Q15436 2 +WWE domain [IPR004170] 0.6617910447761269 1.8614375281828024 0.0626824150731919 1.0 0.1030836337202462 3 Q7Z6Z7,Q7Z2W4 2 +Pseudouridine synthase II, N-terminal [IPR002501] 0.6562220232766316 1.8575483021541963 0.0632331858436439 1.0 0.1039266775777621 2 O60832 1 +E3 ligase, CCCH-type zinc finger [IPR041367] 0.6611372777973973 1.834844861972976 0.0665286793272947 1.0 0.1077995631398788 4 Q6P158 1 +PUA domain [IPR002478] 0.661132155461922 1.8348190418925816 0.06653250623466 1.0 0.1077995631398788 4 Q9ULC4 1 +SAM domain [IPR041418] 0.6511489107729004 1.8320365996334251 0.0669459679625366 1.0 0.1078421353578236 2 Q12800 1 +CP2 transcription factor [IPR007604] 0.6511489107729004 1.8320365996334251 0.0669459679625366 1.0 0.1078421353578236 2 Q12800 1 +Ribosomal protein S4/S9, N-terminal [IPR001912] 0.6499552372426133 1.8260259410974615 0.0678463544294161 1.0 0.1084109965691212 2 P46781 1 +R3H domain [IPR001374] 0.6588777239780501 1.8234499880214703 0.0682352651639297 1.0 0.1086474085183018 4 P38935 1 +DDT domain [IPR018501] 0.6566539998145894 1.8122257448109584 0.0699513226517001 1.0 0.1105669108038763 4 Q9UIF9,Q12830 2 +WHIM2 domain [IPR028941] 0.6566539998145894 1.8122257448109584 0.0699513226517001 1.0 0.1105669108038763 4 Q9UIF9,Q12830 2 +RNA-binding S4 domain [IPR002942] 0.6501492537313502 1.8027923827534809 0.0714208269125926 1.0 0.112433133065751 3 P62701,P46781 2 +Phosphoribosyltransferase domain [IPR000836] 0.66089034956677 1.789424796637244 0.0735464288308578 1.0 0.114675090512471 6 P00492,P07741,P11172,O60256,P11908 5 +eRF1 domain 3 [IPR005142] 0.6299612056102619 1.7249174211234233 0.084542355540695 1.0 0.1269999552637232 2 P62495 1 +eRF1 domain 2 [IPR005141] 0.6299612056102619 1.7249174211234233 0.084542355540695 1.0 0.1269999552637232 2 P62495 1 +eRF1 domain 1/Pelota-like [IPR005140] 0.6299612056102619 1.7249174211234233 0.084542355540695 1.0 0.1269999552637232 2 P62495 1 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.6299870169585577 1.7005908447202704 0.0890198445181393 1.0 0.1321956819138582 3 Q96F07 1 +GAR domain [IPR003108] 0.6216054908982264 1.682435275350053 0.0924844659062504 1.0 0.1363007948050473 2 Q9UPN3 1 +Sec24-like, trunk domain [IPR041742] 0.6255909064035825 1.678207500493034 0.0933065980304261 1.0 0.137141574775033 3 O95486 1 +Zinc finger, double-stranded RNA binding [IPR022755] 0.6285762648890505 1.6696939316512809 0.0949799349946318 1.0 0.1391507112152536 4 Q9UKJ3,Q5F1R6 2 +Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.6405864286062805 1.6665153114582931 0.0956108211100779 1.0 0.1397744031786278 7 P25787,P25789,P28066,P60900 4 +THIF-type NAD/FAD binding fold [IPR000594] 0.6392389978483435 1.6596156663092636 0.0969917946612535 1.0 0.1412627688144927 7 P22314,O95352,Q9UBT2,Q13564 4 +Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.6467956115427498 1.644262131356222 0.1001220679186296 1.0 0.1442795531878719 10 Q9UBF2,O14617,O00203,O94973,P53618,Q10567,Q9Y678 7 +AGC-kinase, C-terminal [IPR000961] 0.6489744308849925 1.6390266755651164 0.1012077042722683 1.0 0.1454593850959553 11 Q16512,Q13464,P17612,O75116,Q15418,P31751,Q16513 7 +La-type HTH domain [IPR006630] 0.6262371192624951 1.6348593628094197 0.1020785330032918 1.0 0.1464792008604372 5 Q6PKG0 1 +Initiation factor eIF-4 gamma, MA3 [IPR003891] 0.6285260992492431 1.6244383158604754 0.1042822951706323 1.0 0.1490616694188417 6 O43432,Q53EL6,Q5C9Z4,Q04637 4 +Chromo domain [IPR023780] 0.6356348754808778 1.622225926480874 0.1047549823289408 1.0 0.1495323870331922 8 Q9P2D1,Q14839,O14646,Q9HCK8 4 +PWI domain [IPR002483] 0.6143536314036896 1.5969782500132816 0.1102705555556875 1.0 0.15585438998405 4 Q5T8P6,Q8IYB3 2 +Arf GTPase activating protein [IPR001164] 0.6010146225007396 1.5772364580574227 0.1147411270140723 1.0 0.1605079933846751 2 Q8IYB5 1 +WSTF/Acf1/Cbp146 [IPR013136] 0.5974336019098709 1.558874036570967 0.1190261965429395 1.0 0.1648101552741414 2 Q9UIG0 1 +Gamma-adaptin ear (GAE) domain [IPR008153] 0.5959415099970092 1.5512177240399792 0.120849516043594 1.0 0.1660690525561239 2 O43747 1 +VHS domain [IPR002014] 0.5941509997015748 1.542026156186154 0.1230672376399388 1.0 0.1685217198838358 2 Q9UJY4 1 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.6436018090428289 1.5275860773851917 0.1266153406865728 1.0 0.1719117106980125 17 Q70CQ2,Q9UPT9,P40818,Q93008,Q96RU2 5 +Ubiquitin specific protease domain [IPR028889] 0.6436018090428289 1.5275860773851917 0.1266153406865728 1.0 0.1719117106980125 17 Q70CQ2,Q9UPT9,P40818,Q93008,Q96RU2 5 +Helicase superfamily 1/2, ATP-binding domain [IPR014001] 0.5475597637806159 1.5146221944852696 0.129868108286892 1.0 0.1751933639018716 70 Q9H6S0,Q8IY37,P46063,P51532,P38935,Q12873,Q9P2D1,Q9GZR7,Q9NRZ9,O14981,P26196,Q96L91,Q14839,Q9NUL7,Q8N3C0,Q7L014,Q6P158,Q92499,Q7Z478,Q9H4L7,Q8IX18,Q14240,Q9UNY4,Q15477,Q9HCK8,O60231,O14646,Q14147,Q86WJ1,Q14527 30 +ENTH domain [IPR013809] 0.5875857952849854 1.5082882246260878 0.1314807756555815 1.0 0.1766691881959861 2 Q14677 1 +Pleckstrin homology domain, spectrin-type [IPR001605] 0.5866905401372654 1.5036834804414294 0.1326628847250819 1.0 0.1777814277871209 2 O15020 1 +Pleckstrin homology domain 9 [IPR041681] 0.5866905401372654 1.5036834804414294 0.1326628847250819 1.0 0.1777814277871209 2 O15020 1 +Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.1784373568533501 2 P22314 1 +Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.1784373568533501 2 P22314 1 +Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.1784373568533501 2 P22314 1 +Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.1784373568533501 2 P22314 1 +FYVE zinc finger [IPR000306] 0.5905349374680562 1.4745783977289544 0.140325926193551 1.0 0.1849072286641327 4 Q9P2R3,Q7Z3T8 2 +Zinc finger, FYVE-related [IPR017455] 0.5905349374680562 1.4745783977289544 0.140325926193551 1.0 0.1849072286641327 4 Q9P2R3,Q7Z3T8 2 +JmjC domain [IPR003347] 0.5966607294155608 1.4403865976700376 0.1497580533247062 1.0 0.1949788319683824 7 P29375,Q7LBC6,Q9UPP1 3 +Helicase/SANT-associated domain [IPR014012] 0.5762105494044437 1.4248202340446263 0.1542091717982512 1.0 0.2000857905952644 3 Q96L91 1 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.5748859890618004 1.417985604009797 0.156194967805423 1.0 0.2017732284422805 3 O00203 1 +Zinc finger, UBR-type [IPR003126] 0.5786595212859302 1.4133317597332136 0.1575581998802555 1.0 0.2024531325144004 4 O95071 1 +MCM N-terminal domain [IPR027925] 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.2024531325144004 6 P33993,P33991,P33992 3 +MCM domain [IPR001208] 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.2024531325144004 6 P33993,P33991,P33992 3 +MCM OB domain [IPR033762] 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.2024531325144004 6 P33993,P33991,P33992 3 +MCM, AAA-lid domain [IPR041562] 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.2024531325144004 6 P33993,P33991,P33992 3 +WHEP-TRS domain [IPR000738] 0.577422984890837 1.4069482699106637 0.15944272871936 1.0 0.2038861735149019 4 P07814 1 +Brix domain [IPR007109] 0.5771826305803551 1.405707351965885 0.1598110429336223 1.0 0.2040698650394193 4 Q9NQ55,Q9H9Y2 2 +MAGE homology domain [IPR002190] 0.5721785776566513 1.404011618022005 0.1603153899769058 1.0 0.20427902968959 3 Q9Y5V3 1 +Mu homology domain [IPR028565] 0.5763924696866571 1.4016276012755398 0.161026480330015 1.0 0.2049496304994352 4 Q9BXS5,P48444 2 +NFkappaB IPT domain [IPR033926] 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.2056412323226948 2 Q00653 1 +Rel homology dimerisation domain [IPR032397] 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.2056412323226948 2 Q00653 1 +Rel homology domain (RHD), DNA-binding domain [IPR011539] 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.2056412323226948 2 Q00653 1 +Cullin protein, neddylation domain [IPR019559] 0.584652330638329 1.3782615919613728 0.1681225369852104 1.0 0.2116091978220315 7 Q13618,Q14999,Q13616 3 +Cullin homology domain [IPR016158] 0.584652330638329 1.3782615919613728 0.1681225369852104 1.0 0.2116091978220315 7 Q13618,Q14999,Q13616 3 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.5804975324968462 1.3770249310752956 0.1685045399688531 1.0 0.2118942646124249 6 Q06124,Q13614,Q9ULE6 3 +Amidohydrolase-related [IPR006680] 0.5760189925144992 1.3764096733571969 0.1686948348034032 1.0 0.2119614794372365 5 Q9BPU6 1 +Helicase, C-terminal [IPR001650] 0.5295238734288741 1.369741713260191 0.1707675425411343 1.0 0.2134594281764179 70 Q9H6S0,Q8IY37,P46063,P51532,Q12873,Q9P2D1,Q9GZR7,Q9NRZ9,O14981,P26196,Q96L91,Q14839,Q9NUL7,Q8N3C0,Q7L014,Q6P158,Q92499,Q7Z478,Q9H4L7,Q8IX18,Q14240,Q9UNY4,Q15477,Q9HCK8,O60231,O14646,Q14147,Q86WJ1,Q14527 29 +Forkhead-associated (FHA) domain [IPR000253] 0.5987234043684925 1.3616201202015576 0.1733178021621433 1.0 0.216052612484831 12 O96017,Q15058,Q14676,P55196,P85037,Q5SW79,O60333 7 +Sterile alpha motif domain [IPR001660] 0.5699920859526256 1.3226928527335933 0.1859375413489505 1.0 0.2271088301998612 6 Q9Y3Z3,O15357 2 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.5487914055505759 1.3081025558883586 0.1908385266782453 1.0 0.2321584755349189 2 Q93009 1 +EB1, C-terminal [IPR004953] 0.5472993136377103 1.3003872891797508 0.1934682641813276 1.0 0.2346243969266212 2 Q15555 1 +GRAM domain [IPR004182] 0.555216243104849 1.2921959493210449 0.1962892941343048 1.0 0.2375170188792099 4 O95248 1 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.5528009990698771 1.2797103645232897 0.2006470181004642 1.0 0.2413965228802495 4 Q86TI2,Q4J6C6 2 +Protein kinase domain [IPR000719] 0.5124482493926021 1.275781079236188 0.2020329178092879 1.0 0.2425595370974674 71 P36507,P49841,P68400,Q13523,O75116,P31751,Q00535,O14965,P78362,P17612,Q9NYV4,Q00534,Q9H2G2,Q15418,Q7KZI7,P19784,Q16513,O14976,P11802,Q96SB4,O15111,Q13418,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q99570,P53350 31 +Ribosome receptor lysine/proline rich [IPR007794] 0.5377499253953962 1.2510090719328963 0.2109311676398217 1.0 0.2501250791203283 2 Q86UP2 1 +MRG domain [IPR026541] 0.5371530886302491 1.2479233250681243 0.2120591378045342 1.0 0.2513122866541672 2 Q15014 1 +SH2 domain [IPR000980] 0.5703705937598986 1.2477659204771805 0.2121167924053522 1.0 0.2513122866541672 10 Q06124,O15357,P46109,P19174,P40763 5 +Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186] 0.5514339917080504 1.2267251714708265 0.2199259035986616 1.0 0.2598864212083057 6 Q08209,O00743 2 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2631035908684043 7 P04350,Q13885,Q9BUF5 3 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2631035908684043 7 P04350,Q13885,Q9BUF5 3 +Protein kinase, C-terminal [IPR017892] 0.5457083089815294 1.1971484628854103 0.2312486933612951 1.0 0.2699882988044256 6 Q16512,Q16513,P31751 3 +Dynamin, GTPase domain [IPR001401] 0.5291364840147281 1.1816087835365898 0.2373609667163094 1.0 0.2753548890174301 3 P50570 1 +Phospholipase/carboxylesterase/thioesterase [IPR003140] 0.5280597014925439 1.176051877052496 0.2395741463737621 1.0 0.2776751670474491 3 O75608,O95372 2 +Domain of unknown function DUF4217 [IPR025313] 0.5326390079429628 1.1755651577230306 0.2397686855275771 1.0 0.2776751670474491 4 Q13206,Q8NHQ9 2 +Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0.5413588615496538 1.1746993393956675 0.2401150237646545 1.0 0.2778401018083582 6 P26640,P41252 2 +Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0.5413588615496538 1.1746993393956675 0.2401150237646545 1.0 0.2778401018083582 6 P26640,P41252 2 +Endonuclease/exonuclease/phosphatase [IPR005135] 0.5404828795453247 1.1701803619478093 0.2419283939672138 1.0 0.2789906362931265 6 Q01968,P27695 2 +NUC153 [IPR012580] 0.5198448224410508 1.1585119324045594 0.2466551850540417 1.0 0.2839608699925068 2 Q9BSC4 1 +Glutathione S-transferase, C-terminal [IPR004046] 0.5514526703098613 1.149650659319253 0.2502877840099278 1.0 0.2870395088244809 10 P07814,P28161,Q13155,O43324,P21266,P26640,P26641 7 +Serine-tRNA ligase catalytic core domain [IPR033729] 0.5171590569978994 1.1446585994358836 0.2523506076234609 1.0 0.2884473012193519 2 P49591 1 +Rhodanese-like domain [IPR001763] 0.5394906269427274 1.1446559779406833 0.2523516939841963 1.0 0.2884473012193519 7 P30307,Q99956 2 +MIF4G-like, type 3 [IPR003890] 0.5430368612610564 1.14328453351207 0.2529204744240281 1.0 0.2887448099149023 8 Q5C9Z4,Q04637,Q9HAU5 3 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.5364745111580584 1.1291108525814442 0.258851073740411 1.0 0.2943793197931108 7 O75116,Q13464 2 +Threonyl/alanyl tRNA synthetase, SAD [IPR012947] 0.5244397596095325 1.110073955378902 0.2669671592135585 1.0 0.3008624933237994 5 P26639 1 +Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872] 0.5073112503730106 1.0939392531380674 0.2739816215532231 1.0 0.3071163795691209 2 P56192 1 +Methioninyl-tRNA synthetase core domain [IPR033911] 0.5073112503730106 1.0939392531380674 0.2739816215532231 1.0 0.3071163795691209 2 P56192 1 +Methionyl/Leucyl tRNA synthetase [IPR015413] 0.5073112503730106 1.0939392531380674 0.2739816215532231 1.0 0.3071163795691209 2 P56192 1 +Cullin, N-terminal [IPR001373] 0.53223254299934 1.0876216577178608 0.2767621656485528 1.0 0.3095719677118531 8 Q13618,Q14999,Q13616 3 +Rpn11/EIF3F, C-terminal [IPR024969] 0.5085585460922579 1.051725217703685 0.2929256376598848 1.0 0.3244806352126772 4 O00487,Q7L5N1 2 +NSD, Cys-His rich domain [IPR041306] 0.4953745150701153 1.0326765063068228 0.3017553116027685 1.0 0.3338543337870662 2 Q96L73 1 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.4950638765261991 1.006564469736526 0.3141441158577431 1.0 0.346015649034903 3 Q06124 1 +Chromo/chromo shadow domain [IPR000953] 0.523440357896177 1.005453213483374 0.3146786674056754 1.0 0.3464643913860467 10 Q9P2D1,Q14839,O14646,Q9HCK8 4 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.5273215999703011 0.99111209521427 0.3216308475731781 1.0 0.3538328864097337 12 Q8NEC7,O00299,Q9Y696,P26640,P26641 5 +SMCs flexible hinge [IPR010935] 0.5002323262689812 0.986196679432245 0.3240366084354822 1.0 0.3561919152830533 5 Q9NTJ3,A6NHR9 2 +Histone deacetylase domain [IPR023801] 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.3563249220986202 2 Q13547 1 +PABP, RNA recognition motif 2 [IPR045305] 0.4813488510892175 0.9611183594630942 0.3364926594314581 1.0 0.368546019674728 2 P11940 1 +PPM-type phosphatase domain [IPR001932] 0.4882054344580557 0.9480161083037252 0.3431212537925143 1.0 0.3755041833673098 4 P49593,O15355,Q9H0C8 3 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.4780662488809171 0.9444545985915228 0.3449373921247658 1.0 0.3771887614526432 2 P51116 1 +Ubiquitin-associated domain [IPR015940] 0.528807356737516 0.9253325846829248 0.3547929342194109 1.0 0.3871889250091689 17 Q96EP0,Q96S82,Q7Z6Z7,P22681,Q13501,Q6P158 6 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.49513025373902 0.918067312978954 0.3585836263170536 1.0 0.3910125577086719 7 Q9H4M9,P50570,Q9H223 3 +Dynamin, N-terminal [IPR045063] 0.49513025373902 0.918067312978954 0.3585836263170536 1.0 0.3910125577086719 7 Q9H4M9,P50570,Q9H223 3 +TGS [IPR004095] 0.4875780611616304 0.9001079557200667 0.3680628026350028 1.0 0.401188454872153 6 P55039,P26639,Q9Y295 3 +Domain of unknown function DUF1899 [IPR015048] 0.4727487079408584 0.8701923579439128 0.384195291529847 1.0 0.4179369937799733 4 P57737 1 +Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.4815123445776101 0.869719016109553 0.3844539775420261 1.0 0.4180515118922671 6 Q10567,O94973,O95782 3 +Ku70/Ku80, N-terminal alpha/beta [IPR005161] 0.4613548194568633 0.8602484087036858 0.3896521251874953 1.0 0.4228602314360513 2 P13010 1 +Ku70/Ku80 C-terminal arm [IPR005160] 0.4613548194568633 0.8602484087036858 0.3896521251874953 1.0 0.4228602314360513 2 P13010 1 +Ku70/Ku80 beta-barrel domain [IPR006164] 0.4613548194568633 0.8602484087036858 0.3896521251874953 1.0 0.4228602314360513 2 P13010 1 +W2 domain [IPR003307] 0.4823068869979474 0.8538020188659422 0.3932146956990894 1.0 0.426386806916044 7 Q13144,Q04637 2 +Kinesin motor domain [IPR001752] 0.5046108492695173 0.8447385604056377 0.398256824916225 1.0 0.4315108739151941 14 Q15058,Q9BW19,Q96Q89,Q9Y496,O00139,Q99661,O60333 7 +BRCT domain [IPR001357] 0.4958257069812571 0.8319539528055736 0.4054349363473064 1.0 0.4385907906099285 12 P35251,P49917,Q92547,P09874 4 +WW domain [IPR001202] 0.4956899486543342 0.8312784384499307 0.4058163522172944 1.0 0.4388291903937013 12 Q8N1G2,P46940 2 +NAD(P)-binding domain [IPR016040] 0.4547896150402755 0.8275071871886387 0.4079496501112758 1.0 0.440961045836266 2 P30043 1 +BRO1 domain [IPR004328] 0.453297523127415 0.8200968641537962 0.4121608897533304 1.0 0.445159898762515 2 Q5VW32 1 +CTLH, C-terminal LisH motif [IPR006595] 0.466453685921292 0.8165500839067696 0.4141855907615577 1.0 0.4471694670464519 5 Q9H7D7,O94967,Q9UL63 3 +Aminoacyl-tRNA synthetase, class II [IPR006195] 0.4902902212121899 0.8044986655643303 0.4211090397079478 1.0 0.4541045244179492 12 O43776,P07814 2 +Radical SAM [IPR007197] 0.4507493000817851 0.7840417055701081 0.4330156390560267 1.0 0.4663903622243766 3 Q9H9T3 1 +Elp3/MiaB/NifB [IPR006638] 0.4507493000817851 0.7840417055701081 0.4330156390560267 1.0 0.4663903622243766 3 Q9H9T3 1 +Calcineurin-like phosphoesterase domain, ApaH type [IPR004843] 0.4650595949062607 0.7687200718190735 0.4420595067037118 1.0 0.4757551958007957 7 Q08209,O00743 2 +Glutathione S-transferase, N-terminal [IPR004045] 0.4560281360750379 0.7249253387787228 0.4684978350033892 1.0 0.5030167850213695 7 P28161,P21266,P26641,O00299 4 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.4579417662636538 0.7155828658319273 0.474248956610805 1.0 0.5087907113245841 8 O00487,Q6P2Q9,Q7L5N1,Q92905 4 +Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.4288272157564819 0.7005183466336176 0.483603651631324 1.0 0.5176040654734321 2 O95336 1 +Peptidase M24 [IPR000994] 0.4446635974282614 0.670701256345305 0.5024108623464765 1.0 0.5371006668866805 7 Q9NQW7,P50579,Q9Y5B9,Q9UQ80 4 +Zinc finger, GATA-type [IPR000679] 0.4361426593947662 0.6697469259970914 0.5030191320340585 1.0 0.5375400528599252 5 Q92908,O94776 2 +Pumilio homology domain [IPR033133] 0.4159952253058747 0.6395978529544704 0.5224340786844623 1.0 0.557194858870904 2 Q15397 1 +Anaphase-promoting complex subunit 4, WD40 domain [IPR024977] 0.4413212951039477 0.6369323152835754 0.5241689324121912 1.0 0.5588264244222305 8 Q9UJX5,O94967,Q8TEQ6,P53621 4 +GTP binding domain [IPR006073] 0.4566069386357827 0.6271284554148094 0.5305750359302355 1.0 0.5647735839803388 13 Q8TCY9,P36915 2 +AMP-binding enzyme, C-terminal domain [IPR025110] 0.4247311827956855 0.6163893094943799 0.537637607345959 1.0 0.5718432786954482 5 Q4G176,O14975,Q96CM8,Q6P1M0 4 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.4397624621237203 0.5958995482834503 0.5512423350204565 1.0 0.5856278218053582 10 Q9NR09 1 +Glutaredoxin [IPR002109] 0.4149787803470544 0.5919628809598511 0.5538754448543013 1.0 0.5881958640794899 4 Q16881 1 +Sulfatase, N-terminal [IPR000917] 0.4037600716204089 0.5829388314397551 0.5599344786841418 1.0 0.5943986966943071 2 P15289 1 +Hexokinase, N-terminal [IPR022672] 0.4001790510295411 0.5666525199719206 0.5709502850120776 1.0 0.6049142794159842 2 P52789 1 +Hexokinase, C-terminal [IPR022673] 0.4001790510295411 0.5666525199719206 0.5709502850120776 1.0 0.6049142794159842 2 P52789 1 +OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.411701727349826 0.5570744611744683 0.5774765557365371 1.0 0.6113533855408172 5 P55039,Q9Y295 2 +Helicase/UvrB, N-terminal [IPR006935] 0.4005970149253838 0.5475341492398155 0.5840118159943009 1.0 0.6175522695321962 3 Q9UPY3,Q92900 2 +Dbl homology (DH) domain [IPR000219] 0.4192793599458885 0.5368333361958211 0.5913827423960982 1.0 0.624377362661514 8 Q6XZF7,Q9H8V3,Q92974 3 +Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479] 0.4065750213945232 0.5153976197448193 0.6062751954348644 1.0 0.6393575493653272 6 P27708 1 +B-box, C-terminal [IPR003649] 0.385684045452672 0.4631248345243927 0.6432748898628471 1.0 0.6757610157580024 4 O15344,Q9UPN9 2 +Pleckstrin homology domain [IPR001849] 0.4524675931261321 0.439871970795312 0.6600298376147606 1.0 0.6922945756351897 31 Q13464,O60333,O75116,P50570,Q92974,P31751,P22059,O95248,Q9BZF3,Q14155,O14654 11 +Translation elongation factor EFTu/EF1A, C-terminal [IPR004160] 0.3789766393766463 0.4352585034781015 0.6633748017304877 1.0 0.6952678210444534 4 Q05639 1 +AMP-dependent synthetase/ligase [IPR000873] 0.379485645933004 0.3582766373849801 0.7201362999081464 1.0 0.7501419790709859 9 O14975,Q6P1M0,P33121,Q4G176,O95573,Q9P265,Q96CM8,Q86V21 8 +FAD linked oxidase, N-terminal [IPR006094] 0.3467621605490896 0.3444066538170021 0.7305404855921669 1.0 0.7592383002435754 2 Q15392 1 +FAD-binding domain, PCMH-type [IPR016166] 0.3467621605490896 0.3444066538170021 0.7305404855921669 1.0 0.7592383002435754 2 Q15392 1 +PWWP domain [IPR000313] 0.3643783625449576 0.3303577434724696 0.7411296666278393 1.0 0.7676086436947405 7 Q7Z4V5 1 +EH domain [IPR000261] 0.3586045067075022 0.3236886156224528 0.7461737906537769 1.0 0.7725393539253579 6 Q9H4M9,Q9H223 2 +Phox homology [IPR001683] 0.3794214161068355 0.3198917879971297 0.7490503632782677 1.0 0.7749287167552313 12 O00443,A1X283,Q9Y5X3,Q53T59,O60493 5 +CRAL-TRIO lipid binding domain [IPR001251] 0.3525935756581859 0.3172668731691952 0.7510411112702498 1.0 0.7766933693402014 5 P21359 1 +DEAD/DEAH box helicase domain [IPR011545] 0.423696920447161 0.3077378274924039 0.7582818334334405 1.0 0.7838839135455711 47 O60231,Q8IY37,Q6P158,P26196,P46063,Q9NUL7,Q7Z478,Q8N3C0,Q8IX18,Q7L014,Q14240,Q9GZR7,Q9H6S0,Q15477 14 +Proteasome component (PCI) domain [IPR000717] 0.3907828875443119 0.3063125719873291 0.7593666679255382 1.0 0.7847076868020825 17 Q14152,Q5JVF3,Q15008 3 +NLE [IPR012972] 0.3345270068636227 0.300264207113469 0.7639756328634366 1.0 0.7891711901261808 2 Q9NVX2 1 +CBS domain [IPR000644] 0.3487746563060292 0.2763847156474194 0.7822525948424097 1.0 0.8071330257272118 7 P51790,P54619,Q6P4Q7,P12268,P51798,P20839 6 +Zinc finger, CCCH-type [IPR000571] 0.3778520855839247 0.2543967230348657 0.7991890823505239 1.0 0.8230499808787519 18 Q8IWR0,Q6P158 2 +Chaperone DnaJ, C-terminal [IPR002939] 0.3315094731115741 0.2468716933057943 0.805007523861895 1.0 0.8287289393742591 5 P31689,Q9UBS4 2 +Butyrophylin-like, SPRY domain [IPR003879] 0.3138811722168189 0.2071305611580002 0.8359078952550973 1.0 0.8576238759676733 4 Q14258 1 +SPRY-associated [IPR006574] 0.3138811722168189 0.2071305611580002 0.8359078952550973 1.0 0.8576238759676733 4 Q14258 1 +WH2 domain [IPR003124] 0.3079154664812588 0.2025136625358222 0.8395151785295616 1.0 0.8610007005995691 3 O00401 1 +Rad60/SUMO-like domain [IPR022617] 0.2981199641897967 0.1877714851787829 0.8510557896696744 1.0 0.8718522657330311 2 Q8NCF5 1 +MPN domain [IPR037518] 0.3313073411695041 0.1823684820534163 0.8552935586910397 1.0 0.8758643169609482 11 P51665,Q7L5N1,Q8TAT6,Q92905,O00487,Q6P2Q9 6 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.3156007172743513 0.1790322036095381 0.8579124153666406 1.0 0.8782161276762193 7 P41240,Q13308,Q9UHY1,Q13546,O43318,Q13418 6 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.3059456229459141 0.1645479725540272 0.8692997847352182 1.0 0.8888177563671563 6 Q15019,Q9UHD8,Q16181,Q14141,Q9P0V9 5 +Biotin carboxylase-like, N-terminal domain [IPR005481] 0.3013739545997528 0.1633714606091268 0.8702259721055314 1.0 0.8888177563671563 5 P11498,Q13085,O00763,Q96RQ3 4 +Biotin carboxylation domain [IPR011764] 0.3013739545997528 0.1633714606091268 0.8702259721055314 1.0 0.8888177563671563 5 P11498,Q13085,O00763,Q96RQ3 4 +Biotin carboxylase, C-terminal [IPR005482] 0.3013739545997528 0.1633714606091268 0.8702259721055314 1.0 0.8888177563671563 5 P11498,Q13085,O00763,Q96RQ3 4 +Translation elongation factor EFTu-like, domain 2 [IPR004161] 0.3148288569368215 0.1590104712630455 0.8736606239239382 1.0 0.8916573783493376 9 Q05639,O60841,P13639 3 +Translational (tr)-type GTP-binding domain [IPR000795] 0.3137545201151811 0.1270937245172301 0.8988662182949791 1.0 0.9156674560201188 13 Q05639,O60841,O00178,P13639 4 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.2924148904614729 0.1058542675368064 0.9156979793457812 1.0 0.9319468854669792 10 P62942 1 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.2696327261869153 0.1056337584920756 0.9158729391855304 1.0 0.9319468854669792 4 Q8WVV9,Q9UKA9,P26599 3 +G-patch domain [IPR000467] 0.3000252526136889 0.0965457284919714 0.9230871574384628 1.0 0.9385867552312728 14 Q8N1G2,Q9UBB9,Q92917,Q9UKJ3 4 +SANT/Myb domain [IPR001005] 0.2930811009261421 0.0905665299493566 0.9278370278321098 1.0 0.9427128638488064 13 Q15554,Q96L91,Q99459,O94776,Q99543 5 +IPT domain [IPR002909] 0.2625448028673758 0.0873919001013488 0.9303600075295686 1.0 0.9449239733574636 5 Q96KP1,O15031,Q00653,Q04206 4 +DnaJ domain [IPR001623] 0.3077152895579033 0.0861453862457342 0.931350844690501 1.0 0.945577888145162 19 Q9NZJ4,Q9NVH1,Q9UBS4,O14976,Q5F1R6,O75165,P31689 7 +Ubiquitin-like domain [IPR000626] 0.2908222916862877 0.0743899938503117 0.9407000704942368 1.0 0.954003607032674 16 Q96S82,Q9NZJ4,Q86UV5,P46379,Q99426,Q8NCF5 6 +Bromodomain [IPR001487] 0.2889819229017348 0.0720440474647413 0.942566854093617 1.0 0.955185822761289 16 Q12830,P25440,Q6PL18,Q9UIG0,Q9ULI0,P51532,Q9UIF9 7 +Double-stranded RNA-binding domain [IPR014720] 0.270259916708528 0.0546945732719034 0.9563817927946544 1.0 0.9688254220689342 15 O75569,P18583,Q9UPY3,O95793,Q9NX74,Q96SI9,Q9NUL3 7 +B30.2/SPRY domain [IPR001870] 0.2446509600400413 0.0438885631526236 0.9649932317996576 1.0 0.9760974597825044 11 Q92499,Q14258,O15344,Q9BUJ2 4 +SPRY domain [IPR003877] 0.2446509600400413 0.0438885631526236 0.9649932317996576 1.0 0.9760974597825044 11 Q92499,Q14258,O15344,Q9BUJ2 4 +Zinc finger C2H2-type [IPR013087] 0.2844149611408619 0.039541170215724 0.9684589300817948 1.0 0.9792395489695328 28 Q96JP5,Q9UKJ3,O43670,Q96KM6,Q86UK7,Q9UNI6,Q5F1R6,O60678,Q7Z2T5,Q9Y2X9 10 +Zinc finger, PHD-type [IPR001965] 0.2750973993323941 0.0349472692782395 0.9721217881801976 1.0 0.9814864293408812 27 Q12830,Q9UPP1,Q14839,Q9UIF9,Q12873,P29375,Q8IWS0 7 +Zinc finger, RING-type [IPR001841] 0.2794540109041477 0.031955829481665 0.9745072758583446 1.0 0.9831663556882596 32 O75592,Q96T51,P22681,Q9UIG0,O15344,Q86UK7,O94822,Q14527,Q14258 9 +C2 domain [IPR000008] 0.2333844353190521 0.0314497085112724 0.974910899077341 1.0 0.9832095484773332 14 Q16513,O00443 2 +ATP-grasp fold [IPR011761] 0.2066519711575119 0.0276045576044977 0.9779775466092512 1.0 0.9858040748901016 9 Q13085,P27708 2 +Zinc finger, PHD-finger [IPR019787] 0.244144279594813 0.0245697218860303 0.9803981704405272 1.0 0.9872819713416248 24 Q12830,Q9UPP1,Q14839,Q9UIF9,Q12873,P29375 6 +RNA helicase, DEAD-box type, Q motif [IPR014014] 0.2295176380099824 0.0198700391861027 0.984147045690885 1.0 0.9906910600323832 26 P26196,Q9NUL7,Q7L014,Q14240,Q9GZR7 5 +SH3 domain [IPR001452] 0.2485628911468539 0.0181798673131921 0.9854953635397984 1.0 0.9910485590378644 38 Q14185,Q9NZQ3,Q6XZF7,A1X283,Q9UQB8,Q9P0V3 6 +Calponin homology domain [IPR001715] 0.1888123367800308 0.0164543108816817 0.9868719517823346 1.0 0.9917108237659864 25 P46940 1 +K Homology domain [IPR004087] 0.1577050165214795 0.016030002125904 0.9872104565320284 1.0 0.9917108237659864 24 Q9UNW9,Q9Y2W6,Q9NZI8,Q92667,Q96AE4,O00425,Q13601,Q96PU8,Q00341,Q15366,Q8IWZ3,Q15637,P61978,P51114,Q9Y6M1,Q06787,O75179,P51116,Q07666,Q15365,Q92945,Q9NRX1,Q96I24 23 +K Homology domain, type 1 [IPR004088] 0.1577524038461559 0.0158630390748036 0.9873436568356406 1.0 0.9917108237659864 25 Q9UNW9,Q9Y2W6,Q9NZI8,Q92667,Q96AE4,O00425,Q96PU8,Q00341,Q8N9N2,Q9NQT5,Q15366,Q8IWZ3,Q15637,P61978,P51114,Q9Y6M1,Q06787,O75179,P51116,Q13868,Q07666,Q15365,Q92945,Q96I24 24 +AAA+ ATPase domain [IPR003593] 0.1671481225523041 0.0104347167657445 0.9916744516820843 1.0 0.9956937659667208 60 Q8NE71,Q96QE3,O43933,P35251,Q8N3C0,Q14204,P38935,Q5T9A4,Q9BVQ7,Q9UG63 10 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b8630ae43fbf821aba23ee2a7536f4f867c18114 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA lid domain [IPR041083]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMMECR1 domain [IPR002733]", "AMP-activated protein kinase, glycogen-binding domain [IPR032640]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATM, catalytic domain [IPR044107]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase [IPR006862]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adaptor protein ClpS, core [IPR003769]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Aftiphilin, clathrin-binding box [IPR029205]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha carbonic anhydrase domain [IPR001148]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Arrestin C-terminal-like domain [IPR011022]", "Arrestin-like, N-terminal [IPR011021]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Association with the SNF1 complex (ASC) domain [IPR006828]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAAT/Acyl-CoA thioester hydrolase C-terminal [IPR014940]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCL10, CARD domain [IPR042143]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Caspase recruitment domain [IPR031964]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cdc6, C-terminal [IPR015163]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA Ligase 4, adenylation domain [IPR044125]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase IV domain [IPR021536]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Death effector domain [IPR001875]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4706 [IPR031600]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-binding protein, first C-terminal SH3 domain [IPR035820]", "Dynamin-binding protein, first N-terminal SH3 domain [IPR035817]", "Dynamin-binding protein, second N-terminal SH3 domain [IPR035818]", "Dynamin-binding protein, third N-terminal SH3 domain [IPR035819]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF31, PUB domain [IPR040641]", "E3 ubiquitin-protein ligase RNF31, UBA-like domain [IPR032065]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FMP27, C-terminal [IPR019443]", "FMP27, GFWDK domain [IPR019441]", "FMP27, N-terminal [IPR019439]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focadhesin/RST, DUF3730 [IPR022542]", "Follistatin-like, N-terminal [IPR003645]", "Follistatin/Osteonectin EGF domain [IPR015369]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G protein-regulated inducer of neurite outgrowth, C-terminal [IPR032745]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GA-binding protein alpha subunit, N-terminal [IPR024668]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GATA-type transcription activator, N-terminal [IPR008013]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HEPN domain [IPR007842]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock factor (HSF)-type, DNA-binding [IPR000232]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IQ motif and SEC7 domain-containing protein, PH domain [IPR033742]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol 1,4,5-trisphosphate/ryanodine receptor [IPR014821]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intimal thickness related receptor, IRP [IPR019336]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transport domain [IPR005821]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KIND domain [IPR011019]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kazal domain [IPR002350]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "L27-2 [IPR015132]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Listerin, zinc finger, RING-type [IPR039804]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "LysM domain [IPR018392]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MALT1 immunoglobulin-like domain [IPR041077]", "MALT1, death domain [IPR037940]", "MAN1, RNA recognition motif [IPR034394]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MGA, conserved domain [IPR032060]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR14, PH-GRAM domain [IPR039803]", "MTMR6, PH-GRAM domain [IPR035998]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Muskelin, N-terminal [IPR010565]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-end aminoacyl transferase, N-terminal [IPR007471]", "N-end rule aminoacyl transferase, C-terminal [IPR007472]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Opioid growth factor receptor (OGFr) conserved domain [IPR006757]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain [IPR019601]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PTHB1, C-terminal domain [IPR028074]", "PTHB1, N-terminal domain [IPR028073]", "PUA domain [IPR002478]", "PUB domain [IPR018997]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Par3/HAL, N-terminal [IPR021922]", "ParB/Sulfiredoxin [IPR003115]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome biogenesis factor 1, N-terminal, alpha/beta [IPR015343]", "Peroxisome biogenesis factor 1, N-terminal, psi beta-barrel fold [IPR015342]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, TIG domain 2 [IPR041362]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plexin-A1, Sema domain [IPR042744]", "Pointed domain [IPR003118]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly A polymerase, head domain [IPR002646]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain [IPR039558]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RIH domain [IPR000699]", "RII binding domain [IPR018459]", "RING finger and SPRY domain-containing protein 1, SPRY domain [IPR035774]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNF31, C-terminal [IPR041031]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Riboflavin kinase domain, bacterial/eukaryotic [IPR015865]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "RyR/IP3R Homology associated domain [IPR013662]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SBF1/SBF2 domain [IPR022096]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3BP4, SH3 domain [IPR035456]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD5, SET domain [IPR044422]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Selenoprotein F/M domain [IPR014912]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydrolase FSH [IPR005645]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TANK binding kinase 1, ubiquitin-like domain [IPR041087]", "TANK-binding kinase 1, coiled-coil domain 1 [IPR041309]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1 domain family member 23, C-terminal domain [IPR045799]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRBP2 , first double-stranded RNA binding domain [IPR044469]", "TRBP2 , second double-stranded RNA binding domain [IPR044470]", "TRBP2 , third double-stranded RNA binding domain [IPR044471]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomere-length maintenance and DNA damage repair [IPR021668]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Trimerisation motif [IPR015049]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UME domain [IPR012993]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 13D, UBA domain [IPR041969]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate heat shock transcription factor, C-terminal domain [IPR010542]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WASP family, EVH1 domain [IPR033927]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZN598/Hel2, RING finger [IPR041888]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZZ3, zinc finger, ZZ-type [IPR041981]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, HIT-type [IPR007529]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain [IPR032828]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMCX3", "ARMT1", "ARRB1", "ARSA", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS3", "BCKDHB", "BCL10", "BCOR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf198", "C1orf35", "C2CD5", "CA8", "CACUL1", "CACYBP", "CAD", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD47", "CDC23", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNPY2", "COA3", "COASY", "COG2", "COIL", "COLEC12", "COMMD10", "COMMD7", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCTN1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERI1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM129B", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0391", "KIAA1671", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MEPCE", "METAP1", "METAP2", "METTL13", "MFN1", "MFN2", "MFSD10", "MGA", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH2", "NCBP1", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPN13", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAI1", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "RELA", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX1", "RIOX2", "RIPK1", "RNASEH2A", "RNASEH2B", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RSPRY1", "RTCA", "RTFDC1", "RTN2", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A2", "SLC27A4", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD5", "SNAP23", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1L", "SPEN", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLCD1", "TLE4", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTC7B", "TTF2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WDR47", "WFS1", "WNK1", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YES1", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF598", "ZNF638", "ZNF644", "ZNF687", "ZNF703", "ZNHIT2", "ZPR1", "ZYX", "ZZZ3"], "leading_proteins": ["AACS", "ABCF1", "ABCF2", "ACACA", "ACACB", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "AFDN", "AIMP2", "AKAP1", "AKT2", "ANAPC4", "ANKFY1", "ANKHD1", "ANKRD17", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP3B1", "AP3D1", "APEX1", "APRT", "ARCN1", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARSA", "ASCC1", "ASCC3", "ATAD2", "ATAD2B", "ATAD3B", "ATAD5", "ATG7", "ATM", "ATR", "AURKA", "BAG6", "BAIAP2", "BAZ1B", "BAZ2A", "BIRC6", "BLVRB", "BPTF", "BRD2", "BROX", "BTAF1", "BUB1", "CAD", "CAMK2G", "CAND2", "CAPN2", "CASP3", "CASP6", "CBL", "CCNB1", "CCNB2", "CCNK", "CDC25C", "CDC5L", "CDK12", "CDK4", "CDK5", "CDK6", "CEP170", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHUK", "CKAP5", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CMTR1", "CNNM4", "COPA", "COPB1", "COPG1", "COPG2", "COPS5", "COPS6", "CORO7", "CRKL", "CSE1L", "CSK", "CSNK2A1", "CSNK2A2", "CTPS1", "CUL1", "CUL3", "CUL7", "CYFIP2", "DDX1", "DDX10", "DDX24", "DDX28", "DDX46", "DDX55", "DDX6", "DHCR24", "DHX16", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DIAPH1", "DICER1", "DIP2B", "DKC1", "DNAAF5", "DNAJA1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DPP9", "DPYSL5", "DRG1", "DRG2", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DYNC1H1", "ECT2", "EEF1A2", "EEF1E1", "EEF1G", "EEF2", "EGLN1", "EHD1", "EHD4", "EIF2B5", "EIF3A", "EIF4A2", "EIF4G1", "EIF4G3", "EIF5B", "ELOA", "ELP3", "EP400", "EPRS", "ETF1", "EXOC2", "EXOSC2", "EXOSC3", "FBXO7", "FHOD1", "FKBP1A", "FLII", "FMR1", "FOXK1", "FTSJ1", "FUBP1", "FUBP3", "FXR1", "FXR2", "GAK", "GALK1", "GATA6", "GBF1", "GCN1", "GEMIN5", "GFPT1", "GGA2", "GMPR2", "GNL1", "GPATCH8", "GPKOW", "GSK3B", "GSTCD", "GSTM2", "GSTM3", "GTPBP1", "HDAC1", "HDGFL2", "HDLBP", "HELLS", "HERC5", "HK2", "HLTF", "HNRNPK", "HNRNPLL", "HNRNPUL1", "HPRT1", "HS1BP3", "HUWE1", "IAH1", "IARS", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGHMBP2", "ILK", "ILKAP", "IMPDH1", "IMPDH2", "INF2", "INPPL1", "IPO11", "IPO4", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRS4", "KCTD12", "KDM1B", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIF14", "KIF1B", "KIF20B", "KIF2A", "KIF2C", "KIF3A", "KIFC1", "KRR1", "KTN1", "LARP1", "LARP7", "LIG1", "LIG4", "LTN1", "LYPLA1", "LYPLA2", "MACF1", "MAGED1", "MAP2K2", "MAP3K7", "MAPK1", "MAPRE2", "MARK2", "MARS", "MCCC1", "MCM4", "MCM5", "MCM7", "MCTS1", "MDC1", "MEPCE", "METAP2", "MID1", "MKLN1", "MORF4L2", "MSH3", "MTA2", "MTMR2", "MYCBP2", "MYH10", "MYH9", "MYO18A", "MYO1D", "MYO6", "NAA50", "NAE1", "NARS", "NCAPD3", "NCKIPSD", "NF1", "NFATC2IP", "NFKB2", "NLE1", "NME1", "NOL10", "NOM1", "NOP2", "NOVA2", "NPLOC4", "NRBP1", "NRDC", "NSD1", "NSUN5", "NSUN6", "OCRL", "OSBP", "OSBPL6", "OTUD4", "OTUD7B", "PA2G4", "PABPC1", "PALD1", "PANK4", "PARP1", "PC", "PCBP1", "PCBP2", "PCID2", "PDCD4", "PDE6D", "PEX1", "PFAS", "PFKL", "PGLS", "PHF6", "PHF8", "PHKB", "PI4KA", "PIK3C2A", "PIK3R4", "PIN4", "PKN1", "PKN2", "PLCG1", "PLK1", "PLXNB2", "PNO1", "POLE", "PPAN", "PPM1F", "PPM1G", "PPP3CA", "PPP6C", "PREPL", "PRKACA", "PRKAG1", "PRKDC", "PRKRA", "PRMT3", "PRPF4B", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PSMA2", "PSMA4", "PSMA5", "PSMA6", "PSMD14", "PSMD6", "PSMD7", "PTBP1", "PTBP2", "PTK7", "PTPN11", "PUM3", "QKI", "RBM26", "RECQL", "RELA", "REXO4", "RFC1", "RIPK1", "RNF31", "RNGTT", "ROCK1", "ROCK2", "RPF1", "RPL24", "RPL27", "RPL27A", "RPS2", "RPS4X", "RPS6KA1", "RPS9", "RUFY1", "SACS", "SAMHD1", "SARS", "SBF1", "SEC16A", "SEC23A", "SEC24A", "SEPT10", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SF1", "SH3BP4", "SH3PXD2B", "SKIV2L", "SLC12A7", "SLC27A2", "SLC27A4", "SLK", "SMAP1", "SMARCA4", "SMARCAD1", "SMC4", "SMCHD1", "SNX3", "SNX5", "SON", "SPATA5L1", "SPTBN2", "SQSTM1", "SRPK1", "SRPK2", "SRRM1", "SSRP1", "STAT3", "STAU1", "STAU2", "STRBP", "SUN2", "SUPT16H", "TARS", "TBCB", "TDRKH", "TERF2", "TFCP2", "TFIP11", "TNPO1", "TNPO3", "TOPBP1", "TRIM25", "TRIM33", "TRMT11", "TRMT1L", "TRRAP", "TSR1", "TTF2", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP3", "TXNRD1", "UBA1", "UBA2", "UBE3C", "UBL7", "UBR5", "UMPS", "UPF1", "UPF2", "URGCP", "USP22", "USP28", "USP34", "USP48", "USP7", "USP8", "USP9X", "VARS1", "VPS51", "VRK1", "WASL", "WDR26", "WDR47", "XPNPEP1", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRN1", "YBX1", "YTHDC2", "ZC3H7A", "ZC3HAV1", "ZFP91", "ZFYVE16", "ZNF207", "ZNF281", "ZNF512B", "ZNF598"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e3a1ea0c31e5893c470154e51d6164ed528098b4 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Cullin [IPR045093]", "1": "Proteasome, subunit alpha/beta [IPR001353]", "2": "Kinesin-like protein [IPR027640]", "3": "Septin [IPR016491]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..37a21376e3ec4608fad6f7f82979329a65eff933 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb0752814b885687df52febc34bd45d734a537bdf9f9fc500e19a754d68e60f9 +size 125453 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b505b3dd07747b91afb005d2f6e5cce419adf4b1 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7b2b6cec173ac6a2733e2e831f51bacf249b49503d0b64ecd8f50340909de7fa +size 142888 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a17be8a02b007ffe31dcf28e5f36bd664cf245a2 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1da840058478bdc57945684faf5756466fd66651fdaf2f80f8a6374166d6766f +size 134726 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..17de34285dbe09282687040ae6513662195e5fba --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:91808eb3e3b7ad60f76c42ab4b018a1cf10f70e0dd2b419daf2897d891c86623 +size 129091 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6c538a1e3036cf3b4c586f1334ce3da9542c8286 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8b4afa75d56eabc0e72522c1fda9984b00a822370dc9ff1513b1bea359394bba +size 723141 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c6a42a380b092d13025c41fea63bbffa3bdbbe9a --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 2569, + "title": "Average number of proteins per term", + "value": 1.2833787465940054 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a07bf58f2c811b6b1e80d57f8c4ffdd778968add --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..46694fef9b9358d36948e220f02daeeb32e78bb2 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,123 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971] 0.9510593852581296 3.232986633349474 0.0012250329443372 0.9571066667076986 0.0117562676663316 2 P42695 1 +Constitutive coactivator of PPAR-gamma [IPR026784] 0.9391226499552352 3.181402382028627 0.0014656390679959 0.9769015253568228 0.0117562676663316 2 Q96EK7 1 +Sister chromatid cohesion protein Pds5 [IPR039776] 0.9018203521336894 3.0180786007824456 0.002543829162056 0.998560448001472 0.0130645465316044 2 Q9NTI5 1 +Dedicator of cytokinesis [IPR026791] 0.9003282602208236 3.011477694748019 0.0025997950235718 0.9987536928039864 0.0131733203462646 2 Q14185 1 +Microtubule associated protein 1 [IPR026074] 0.8868656716417933 2.931720153906914 0.003370903487148 0.999829108157795 0.0144129325125567 3 P78559,P46821 2 +Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852] 0.8761563712324649 2.9038014046013743 0.0036866192790228 0.9999242767870828 0.0149359679932655 2 O75155 1 +Exportin-1/5 [IPR045065] 0.8752611160847437 2.899786371897602 0.003734170645123 0.9999330148904224 0.0149995035500315 2 Q9HAV4 1 +Macrophage migration inhibitory factor [IPR001398] 0.8737690241718874 2.8930903316517553 0.0038147156835786 0.9999455781254856 0.015123463875175 2 P30046 1 +Coatomer gamma subunit [IPR017106] 0.8680990749030086 2.8675960417403994 0.004136032490805 0.999976239876981 0.015718147143311 2 Q9UBF2 1 +DNA mismatch repair MutS family [IPR045076] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9999915658895429 0.0164875533352649 3 P20585 1 +Nucleoside diphosphate kinase [IPR001564] 0.8567591763652582 2.816372053583634 0.0048569384395626 0.9999963025770744 0.0170924313030637 2 P15531 1 +Ribosomal protein S5 [IPR000851] 0.8522829006266746 2.7960652192833404 0.0051728960376729 0.9999983646613736 0.0176952994950488 2 P15880 1 +DNA-directed DNA polymerase, family B [IPR006172] 0.841829786319154 2.727598793112745 0.006379715052978 0.9999999276674446 0.0199628355311823 3 Q07864 1 +Cyclin [IPR039361] 0.833731343283585 2.6903652450914235 0.0071373854115353 0.9999999898082932 0.0211000496228241 3 O95067,P14635 2 +Ribosomal RNA large subunit methyltransferase E [IPR015507] 0.8230378991345861 2.662172682352877 0.0077638037502323 0.999999997985793 0.0222107036017225 2 Q9UET6 1 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.8203521336914312 2.6497695035539595 0.0080546702225758 0.9999999990515892 0.0225900085172461 2 P06737 1 +Glycosyl transferase, family 35 [IPR000811] 0.8203521336914312 2.6497695035539595 0.0080546702225758 0.9999999990515892 0.0225900085172461 2 P06737 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.8173679498657005 2.6359669751594077 0.0083897896469236 0.99999999960189 0.0230990850072794 2 O75116 1 +Casein Kinase 2, subunit alpha [IPR045216] 0.8078185616233879 2.591648474530775 0.0095517315196449 0.9999999999804168 0.0247362885826289 2 P19784 1 +Gamma-tubulin complex component protein [IPR007259] 0.803939122649951 2.573578480635401 0.010065281646816 0.9999999999948328 0.0255510954058009 2 Q96CW5 1 +Glutamyl/glutaminyl-tRNA synthetase [IPR000924] 0.7944437210934608 2.5074153280259246 0.0121617715597377 0.9999999999999776 0.028929284570613 3 P07814 1 +Phosphatidylinositol kinase [IPR015433] 0.780010127074519 2.439230278345425 0.0147185856645222 1.0 0.0332559776360225 3 O00443 1 +DNA helicase, ATP-dependent, RecQ type [IPR004589] 0.7666368248284048 2.397885924553535 0.0164899998501353 1.0 0.0360227972916646 2 P46063 1 +Protein PRRC2 [IPR033184] 0.7699759969531133 2.3915198653320218 0.0167787759293234 1.0 0.0364059758128647 3 P48634 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.7636526410026786 2.3836782529294704 0.0171405810814317 1.0 0.0368795249566149 2 Q96F07 1 +5'-3' exoribonuclease [IPR027073] 0.7615637123246667 2.3737194673307163 0.0176099242381955 1.0 0.0375123510513468 2 Q8IZH2 1 +Ribosome biogenesis protein Bms1/Tsr1 [IPR039761] 0.7594747836466622 2.3637496386053987 0.0180910336617878 1.0 0.0381575250222767 2 Q2NL82 1 +Intracellular chloride channel [IPR002946] 0.7472396299612067 2.30513348003829 0.0211590989371492 1.0 0.0425824520907696 2 O00299 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.7548521946849711 2.297373612911015 0.0215974657240558 1.0 0.043101420680614 4 P46087,Q8TEA1,Q96P11 3 +Peptidase C14 family [IPR002398] 0.7513871449439907 2.2806444125520073 0.0225694969698586 1.0 0.0442265733909739 4 P55212 1 +ATPase family AAA domain-containing protein ATAD2-like [IPR045199] 0.7403760071620442 2.272086026990043 0.0230813148975252 1.0 0.044860017680426 2 Q9ULI0 1 +Ribose-phosphate pyrophosphokinase [IPR005946] 0.7450746268656739 2.272027724057395 0.0230848358791448 1.0 0.044860017680426 3 Q14558,P11908 2 +Myotubularin family [IPR030564] 0.7343283582089616 2.219983095872216 0.0264199151140394 1.0 0.0494339125476818 3 O95248,Q13614 2 +Mesoderm induction early response protein/metastasis-associated protein [IPR040138] 0.7290361086242924 2.2172270431865853 0.0266075804802961 1.0 0.0496765074519481 2 O94776 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.7278424350940016 2.211433733281003 0.0270058160197437 1.0 0.0501285703430069 2 P84085 1 +Adaptor protein complex AP-2, alpha subunit [IPR017104] 0.7269471799462828 2.207086423885334 0.0273080220665518 1.0 0.0505070616911242 2 O94973 1 +DNA ligase, ATP-dependent [IPR000977] 0.7264554192657929 2.181673169469412 0.0291336624664673 1.0 0.0527736104425555 3 P18858 1 +Peptidase S9A, prolyl oligopeptidase [IPR002470] 0.7203819755296925 2.175145365951279 0.0296192247789299 1.0 0.0533229071177793 2 Q4J6C6 1 +HAD-superfamily hydrolase, subfamily IIA [IPR006357] 0.7247138087595152 2.17317790275423 0.0297669302332175 1.0 0.053513816493447 3 Q9H0R4 1 +SLC12A transporter family [IPR004842] 0.7232794341488548 2.16617571011806 0.0302977625119433 1.0 0.0542179931856664 3 Q9Y666 1 +ATP-dependent 6-phosphofructokinase [IPR022953] 0.7226106659490537 2.1629092648762085 0.0305481590431688 1.0 0.0543673607518402 3 P17858 1 +ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914] 0.7226106659490537 2.1629092648762085 0.0305481590431688 1.0 0.0543673607518402 3 P17858 1 +ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161] 0.7226106659490537 2.1629092648762085 0.0305481590431688 1.0 0.0543673607518402 3 P17858 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.7108325872873744 2.1284957346573923 0.0332960032257285 1.0 0.0581491721868774 2 P31689 1 +Peptidase M24, methionine aminopeptidase [IPR001714] 0.7072515666964951 2.1109445255694763 0.0347770803484785 1.0 0.0599612881981486 2 P50579 1 +DNA2/NAM7-like helicase [IPR045055] 0.7138992950237066 2.0977775927538995 0.0359247968016447 1.0 0.0614043932025451 4 Q9HCE1 1 +Initiation factor 4G [IPR045208] 0.7079616596804581 2.091087560121622 0.0365202156383843 1.0 0.0621739125082898 3 Q04637 1 +Small GTPase superfamily, ARF type [IPR024156] 0.7003316869215597 2.0534752255380555 0.0400265100934911 1.0 0.0665123573287054 3 P84085 1 +Fructose-bisphosphate aldolase, class-I [IPR000741] 0.6941211578633251 2.0463245180551017 0.0407244530021897 1.0 0.0674974966210486 2 P09972 1 +Translation Initiation factor eIF- 4e [IPR001040] 0.6938227394807515 2.044851074841573 0.0408695426020817 1.0 0.0675979425932943 2 O60573 1 +Phosphorylase kinase alpha/beta subunit [IPR008734] 0.6920322291853185 2.0360059691053007 0.041749755883627 1.0 0.0684355648994728 2 Q93100 1 +Developmentally regulated GTP-binding protein [IPR045001] 0.6893464637421588 2.022724061914973 0.0431016046771284 1.0 0.0699352981615818 2 Q9Y295 1 +Protein arginine N-methyltransferase [IPR025799] 0.6975433993432151 2.016940726316571 0.0437016993179739 1.0 0.0704768773056341 4 Q99873,O60678 2 +Ribosomal protein S17/S11 [IPR000266] 0.6821844225604151 1.9872227094498405 0.0468977223317907 1.0 0.0745085025790788 2 P62280 1 +SIT4 phosphatase-associated protein family [IPR007587] 0.6812891674127135 1.98277662431144 0.0473923861981755 1.0 0.0751085997181449 2 Q9UPN7 1 +Inosine-5'-monophosphate dehydrogenase [IPR005990] 0.6774097284392708 1.9634888436115536 0.0495893995523473 1.0 0.0779882449030109 2 P20839 1 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.6746435904303525 1.9258481467480435 0.0541233376374425 1.0 0.0833090799224625 3 Q9Y5Y2 1 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.6746435904303525 1.9258481467480435 0.0541233376374425 1.0 0.0833090799224625 3 Q9Y5Y2 1 +Lupus La protein [IPR002344] 0.6639809012235011 1.896459033767968 0.0578993721044591 1.0 0.0880008748664123 2 Q4G0J3 1 +Peptidase C2, calpain family [IPR022684] 0.6636824828409351 1.894964900630568 0.0580970518814949 1.0 0.0881703756262356 2 P17655 1 +Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661] 0.6627872276932245 1.8904813242438077 0.0586936160004678 1.0 0.0888126252043568 2 O43683 1 +Importin beta family [IPR040122] 0.673641940447723 1.8754397116209631 0.0607322562126302 1.0 0.0910806574490642 5 Q8TEX9,Q92973,O00410 3 +Dynein light chain, type 1/2 [IPR001372] 0.6571172784243453 1.8620446659348515 0.0625967945994796 1.0 0.0931260137243744 2 P63167 1 +Sulfotransferase [IPR005331] 0.6532378394509071 1.842548035623538 0.0653950269364147 1.0 0.0962198305839917 2 Q8NCH0 1 +Ribosomal protein S4/S9 [IPR022801] 0.6499552372426133 1.8260259410974615 0.0678463544294161 1.0 0.0988089162283639 2 P46781 1 +Nonaspanin (TM9SF) [IPR004240] 0.6486567164179156 1.795253738236247 0.0726132820837581 1.0 0.1038083036578601 3 Q92544,Q99805 2 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.643688451208579 1.7944214619112142 0.0727459238773122 1.0 0.1039400881205868 2 P62241 1 +Glutathione S-transferase, Mu class [IPR003081] 0.6230975828110962 1.6900306770999427 0.0910220858490413 1.0 0.122684018124967 2 P21266 1 +Proteasome alpha-type subunit [IPR023332] 0.6405864286062805 1.6665153114582931 0.0956108211100779 1.0 0.127596986717813 7 P25787,P25789,P28066,P60900 4 +ThiF/MoeB/HesA family [IPR045886] 0.6392389978483435 1.6596156663092636 0.0969917946612535 1.0 0.1291046220128291 7 P22314,O95352,Q9UBT2,Q13564 4 +La domain containing protein [IPR045180] 0.6262371192624951 1.6348593628094197 0.1020785330032918 1.0 0.13420662808877 5 Q6PKG0 1 +Profilin1/2/3, vertebrate [IPR005454] 0.607579826917332 1.6108519191081117 0.1072120017443478 1.0 0.1393159496617246 2 P07737 1 +Profilin [IPR005455] 0.607579826917332 1.6108519191081117 0.1072120017443478 1.0 0.1393159496617246 2 P07737 1 +Dephospho-CoA kinase [IPR001977] 0.6051924798567505 1.5986356722849704 0.1099015786305384 1.0 0.1418067079366414 2 Q8WVC6 1 +FAM98 [IPR018797] 0.594449418084146 1.5435583824358643 0.1226953537018449 1.0 0.1548155027799801 2 Q8NCA5 1 +Inorganic pyrophosphatase [IPR008162] 0.5932557445538575 1.5374287707978211 0.1241883454041414 1.0 0.1560084120386201 2 Q9H2U2 1 +Spectrin, beta subunit [IPR016343] 0.5866905401372654 1.5036834804414294 0.1326628847250819 1.0 0.1633474980656526 2 O15020 1 +Ubiquitin-activating enzyme E1 [IPR018075] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.1647057697450038 2 P22314 1 +Proteasome B-type subunit [IPR023333] 0.5982131196831939 1.4484117001754584 0.1475019445373724 1.0 0.1772369015512206 7 P20618,P49721,P49720 3 +AP complex subunit beta [IPR026739] 0.5748859890618004 1.417985604009797 0.156194967805423 1.0 0.1846530885606673 3 O00203 1 +Mini-chromosome maintenance protein [IPR031327] 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.1859557460754985 6 P33993,P33991,P33992 3 +Melanoma-associated antigen [IPR037445] 0.5721785776566513 1.404011618022005 0.1603153899769058 1.0 0.1885761157741168 3 Q9Y5V3 1 +NF-kappa-B/Dorsal [IPR000451] 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.1904147091671126 2 Q00653 1 +Clathrin adaptor, mu subunit [IPR001392] 0.5669432960731753 1.376977007062654 0.1685193567366631 1.0 0.1963384251503345 3 Q9BXS5 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.5637181712044194 1.3603153754146438 0.173730144877751 1.0 0.2006801898340569 3 P28072 1 +Cullin [IPR045093] 0.5748431431132425 1.347784549143037 0.1777276888284671 1.0 0.2039224799465529 6 Q13616,Q93034,Q13620,Q13617,Q13618 5 +Ribosomal protein S2 [IPR001865] 0.5553566099671647 1.342044192109222 0.1795816672627257 1.0 0.2054075259118176 2 P08865 1 +MICOS complex subunit MIC26/MIC27 [IPR019166] 0.5544613548194516 1.337416514889264 0.1810867166429544 1.0 0.2064854749470704 2 Q9BUR5 1 +MICOS complex subunit MIC26/MIC27, animal [IPR033182] 0.5544613548194516 1.337416514889264 0.1810867166429544 1.0 0.2064854749470704 2 Q9BUR5 1 +Initiation factor 2B-related [IPR000649] 0.5573134328358286 1.3272151719061134 0.1844375149949448 1.0 0.2093769226787509 3 P49770,Q14232 2 +L-lactate dehydrogenase [IPR011304] 0.5520740077588702 1.3250747817839486 0.1851463493970722 1.0 0.209996013951911 2 P00338 1 +Nuclear pore complex protein [IPR026054] 0.549388242315721 1.3111885728487536 0.1897940620581661 1.0 0.2143971154695325 2 P35658 1 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.5484929871680043 1.3065595263989696 0.1913623500004173 1.0 0.2158034626041974 2 Q9NQT5 1 +Microtubule-associated protein RP/EB [IPR027328] 0.5472993136377103 1.3003872891797508 0.1934682641813276 1.0 0.2175142103640397 2 Q15555 1 +MRG [IPR008676] 0.5371530886302491 1.2479233250681243 0.2120591378045342 1.0 0.2333104603939393 2 Q15014 1 +Ubiquitin/SUMO-activating enzyme E1 [IPR000011] 0.5376119402985153 1.225377497154032 0.2204330214402643 1.0 0.2406682669273434 3 P22314,A0AVT1 2 +Proteasome, subunit alpha/beta [IPR001353] 0.5775725782545593 1.220178930687292 0.2223970521239036 1.0 0.2422977213343122 14 P49721,P28072,P60900,P20618,P25787,P28066,P49720,P25789 8 +Beta tubulin [IPR002453] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2428936805448526 7 P04350,Q13885,Q9BUF5 3 +Tubulin [IPR000217] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2428936805448526 7 P04350,Q13885,Q9BUF5 3 +Oxysterol-binding protein [IPR000648] 0.5491779532515481 1.2150684642992582 0.2243399801128189 1.0 0.2438973376681472 6 Q9BZF3 1 +Dynamin [IPR022812] 0.5291364840147281 1.1816087835365898 0.2373609667163094 1.0 0.2549248844039293 3 P50570 1 +Serine-tRNA ligase, type1 [IPR002317] 0.5171590569978994 1.1446585994358836 0.2523506076234609 1.0 0.2676666849647692 2 P49591 1 +Methionyl-tRNA synthetase [IPR014758] 0.5073112503730106 1.0939392531380674 0.2739816215532231 1.0 0.2855410895619595 2 P56192 1 +Kinesin-like protein [IPR027640] 0.5373489055698752 1.0593528194650896 0.2894391281575936 1.0 0.2987421133936754 11 Q15058,Q96Q89,Q9Y496,Q99661,O60333 5 +Histone deacetylase [IPR003084] 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.3340411812845261 2 Q13547 1 +Histone deacetylase family [IPR000286] 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.3340411812845261 2 Q13547 1 +Tyrosine-tRNA ligase [IPR002307] 0.483437779767224 0.9717406345495412 0.3311795960860764 1.0 0.3408655377985297 2 P54577 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.4813488510892175 0.9611183594630942 0.3364926594314581 1.0 0.3459182241214149 2 P11940 1 +Protein phosphatase 2C family [IPR015655] 0.4882054344580557 0.9480161083037252 0.3431212537925143 1.0 0.3523095527549837 4 P49593,O15355,Q9H0C8 3 +Chloride channel, voltage gated [IPR001807] 0.4765741569680598 0.936892202781896 0.3488140104023292 1.0 0.3578686871899295 2 P51790 1 +Coronin [IPR015505] 0.4727487079408584 0.8701923579439128 0.384195291529847 1.0 0.393539754362112 4 P57737 1 +Structural maintenance of chromosomes protein [IPR024704] 0.45133503433977 0.7642858123509937 0.4446969382821191 1.0 0.4542451031597471 4 Q9NTJ3 1 +Hexokinase [IPR001312] 0.4001790510295411 0.5666525199719206 0.5709502850120776 1.0 0.5808995177013969 2 P52789 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.3936138466129443 0.5371753567576105 0.591146491899762 1.0 0.6004963771018144 2 O75150 1 +Molecular chaperone regulator BAG [IPR039773] 0.3912264995523657 0.526584584863955 0.5984820991056878 1.0 0.6073729471323008 2 Q9UL15 1 +ADF/Cofilin [IPR017904] 0.3928358208955315 0.5132127562515241 0.6078025037883046 1.0 0.6159544900324081 3 P60981,Q9Y281 2 +Plakin [IPR043197] 0.3646395833620863 0.3614737701601906 0.7177453096935467 1.0 0.724513831278083 5 P58107,Q9UPN3 2 +Pyridoxal phosphate-dependent decarboxylase [IPR002129] 0.3449716502536573 0.3377652387516965 0.735540107369167 1.0 0.7416022511112206 2 Q6P996 1 +Ribosomal protein S11 [IPR001971] 0.3270665472993151 0.2748316300723444 0.7834455961840823 1.0 0.7892830339595714 2 P62263 1 +ClpA/B family [IPR001270] 0.320501342882725 0.2534303268074021 0.7999356949897278 1.0 0.8049490013429733 2 Q15645 1 +Septin [IPR016491] 0.3059456229459141 0.1645479725540272 0.8692997847352182 1.0 0.8730379777110147 6 Q15019,Q9UHD8,Q16181,Q14141,Q9P0V9 5 +HnRNP-L/PTB [IPR006536] 0.2696327261869153 0.1056337584920756 0.9158729391855304 1.0 0.9173012010789972 4 Q8WVV9,Q9UKA9,P26599 3 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7d2ab6cf92b21092c52a6f850f79dd1eb04dc777 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 protein sigma [IPR037435]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit beta [IPR039160]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMMECR1 [IPR023473]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit s, mitochondrial [IPR026063]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA thioesterase, long chain [IPR016662]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Arginine-tRNA-protein transferase 1, eukaryotic [IPR017137]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arrestin [IPR000698]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylacetamide deacetylase [IPR017157]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-ketoacyl synthase [IPR000794]", "Beta-lactamase HcpB-like [IPR040239]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CASP8-associated protein 2 [IPR039674]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carbonic anhydrase, alpha-class [IPR023561]", "Carbonic anhydrase-related protein VIII [IPR041877]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Caspase-6 [IPR037554]", "Caspase-8 [IPR033170]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein Cdc6/18 [IPR016314]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein I [IPR012485]", "Centrosomal protein of 170kDa [IPR026644]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1A [IPR029508]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cox20 [IPR022533]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit VIb [IPR003213]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase 4 [IPR029710]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 4 [IPR030612]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Domain of unknown function DUF4525 [IPR027833]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-binding protein [IPR035469]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain Tctex-1 like [IPR005334]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase CBX4 [IPR043531]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase RNF31-like [IPR026254]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enolase-phosphatase E1 [IPR023943]", "Enolase-phosphatase E1, eukaryotes [IPR027511]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Eukaryotic translation initiation factor SUI1 [IPR005874]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 3 [IPR028479]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FMP27 [IPR045167]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Focadhesin [IPR021392]", "Focadhesin/RST1 [IPR045163]", "Folate-sensitive fragile site protein Fra10Ac1 [IPR019129]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G protein-regulated inducer of neurite outgrowth [IPR026646]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GMP reductase [IPR005993]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI-anchor transamidase [IPR028361]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase family 18 [IPR026116]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-binding protein, beta subunit [IPR016346]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Heat shock transcription factor family [IPR027725]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Homeobox protein Hox-A10/abdominal-B-like [IPR046333]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IQ motif and SEC7 domain-containing protein 1 [IPR030737]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor [IPR000493]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 8 [IPR038751]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "K/Cl co-transporter 4 [IPR030354]", "K/Cl co-transporter [IPR000076]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Katanin p60 subunit A1 [IPR028596]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "L-type amino acid transporter [IPR004760]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain-containing protein 1 [IPR028734]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "MAX gene-associated protein [IPR037935]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonyl-CoA epimerase [IPR017515]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial protein C2orf69 [IPR018881]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdopterin biosynthesis MoaE [IPR003448]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Molybdopterin synthase catalytic subunit, eukaryotes [IPR028888]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Mth938 domain-containing protein [IPR034096]", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [IPR033540]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myotubularin-related protein 5 [IPR030574]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-cadherin [IPR030051]", "N-end rule aminoacyl transferase [IPR030700]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NEMP family [IPR019358]", "NF-kappa-B/Dorsal [IPR000451]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural Wiskott-Aldrich syndrome protein [IPR030214]", "Neurochondrin [IPR008709]", "Neurofilament medium polypeptide [IPR027697]", "Neuroplastin [IPR027112]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor NF-kappa-B, p100 subunit [IPR030497]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "OPI10 family [IPR031318]", "ORC ubiquitin ligase 1 [IPR039209]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Opioid growth factor receptor [IPR039574]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Parathyroid hormone-responsive B1 [IPR026511]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome biogenesis factor 1 [IPR025653]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1 [IPR028608]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein BRICK1 [IPR033378]", "Protein C10 [IPR026317]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein KTI12/L-seryl-tRNA(Sec) kinase [IPR013641]", "Protein Kti12 [IPR045106]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG1 [IPR030693]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG9 [IPR039177]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein strawberry notch [IPR026741]", "Protein suppressor of sable-like [IPR045124]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA-binding protein 47 [IPR034442]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RISC-loading complex subunit TRBP2 [IPR028605]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Raftlin family [IPR028169]", "Ragulator complex protein LAMTOR5 [IPR024135]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Riboflavin kinase [IPR023468]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P protein subunit Rpp40 [IPR013893]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAFB-like transcription modulator [IPR034780]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3 domain-binding protein 4 [IPR035455]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Selenoprotein F/M [IPR039992]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase ATM/Tel1 [IPR015519]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfiredoxin [IPR016692]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TBC1 domain family member 23 [IPR039755]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPMT family [IPR008854]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor GATA [IPR039355]", "Transcription factor GATA-6 [IPR028437]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, GA-binding, alpha subunit [IPR016312]", "Transcription factor, T-box [IPR001699]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor NocA-like [IPR022129]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tti2 family [IPR018870]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-protein phosphatase non-receptor type 13 [IPR012153]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "Tyrosyl-DNA phosphodiesterase I [IPR010347]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0688 family [IPR031530]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar (H+)-ATPase G subunit [IPR005124]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat and coiled-coil-containing protein family [IPR028041]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat domain phosphoinositide-interacting protein 4 [IPR032910]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 47 [IPR040067]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 89 [IPR039328]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR44/Dgr2 [IPR040324]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "Xyloside xylosyltransferase 1 [IPR042465]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "ZZ-type zinc finger-containing protein 3 [IPR037830]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger HIT domain-containing protein 2 [IPR039646]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 638 [IPR033096]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-guanine transglycosylase [IPR004803]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1S1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAIAP2", "BANF1", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L13", "BCLAF1", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BROX", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf174", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "C5orf24", "C8orf33", "CA8", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIAO1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWF19L1", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX29", "DIAPH1", "DIAPH2", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FOCAD", "FOXC1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GMFB", "GMPR2", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS2", "INTS3", "INTS5", "INTS8", "INTS9", "IPO4", "IPO5", "IQSEC1", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KATNA1", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LLGL1", "LLPH", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC47", "LRRFIP1", "LSG1", "LSM12", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAK16", "MALT1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA15", "NAA25", "NAA35", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFB10", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NELFB", "NELFCD", "NELFE", "NEMP1", "NES", "NF1", "NFKB2", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NSA2", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "ODR4", "OGDH", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PATL1", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POLA1", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM39", "RBM45", "RBM47", "RBM5", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFK", "RFTN1", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBF1", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFN", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG5", "SMG9", "SMPD4", "SMS", "SMU1", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SRXN1", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARS", "TARS2", "TBC1D23", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDP1", "TECR", "TEDC1", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP2", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC19", "TTC26", "TTC37", "TTC38", "TTI2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBR1", "UBR4", "UBR7", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDR11", "WDR12", "WDR18", "WDR33", "WDR4", "WDR41", "WDR44", "WDR45", "WDR46", "WDR47", "WDR73", "WDR74", "WDR82", "WDR89", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YEATS2", "YEATS4", "YIF1A", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZCCHC3", "ZFYVE16", "ZMPSTE24", "ZNF326", "ZNF503", "ZNF598", "ZNF638", "ZNF687", "ZNF703", "ZNHIT2", "ZPR1", "ZW10", "ZWILCH", "ZZZ3"], "leading_proteins": ["ALDOC", "AP1M1", "AP2A2", "AP3B1", "APOO", "ARF5", "ATAD2B", "ATG7", "BAG5", "BUB1", "CAND2", "CAPN2", "CASP6", "CCNB1", "CCNB2", "CFL2", "CHST14", "CLCN3", "CLIC1", "COPG2", "CORO7", "CSNK2A2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYFIP2", "DCAKD", "DDT", "DNAJA1", "DNM2", "DOCK1", "DRG1", "DSTN", "DYNLL1", "EIF2B1", "EIF2B2", "EIF4E2", "EIF4G1", "EPPK1", "EPRS", "EXOSC3", 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+size 138011 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..eae98784eb5d2884ed0417877946f7b8fa6b8112 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e8ae954eb356b22754d8f7f0e2e23a7884c96b862180164dc7409e056eb7897f +size 282381 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..71b735b41a117791d8fdaf95cd83e11a1aba673e --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Armadillo-type fold [IPR016024] 86 169 7.3260422040752 2.3704916824391577e-13 54.39320388349515 154.9271844660194 -0.7156260328127132 0.5156794927841862 19.860942605814085 17.3539547781392 1.3841368906359015 0.3702561522106249 8.167818169834046e-08 1.2151907044701954e-08 2.6493812231358277e-16 3.530317216832721e-24 +Armadillo-like helical [IPR011989] 59 114 6.030112409419967 1.6384567345316332e-09 38.33980582524272 109.59708737864078 -0.6246385107453618 0.5210365456933685 14.198183528053043 11.00100574670184 1.3356881442801127 0.3736089927477103 3.710089458077823e-06 3.479976812499104e-07 1.3283388362753624e-12 4.5674653130866096e-18 +P-loop containing nucleoside triphosphate hydrolase [IPR027417] 100 306 3.256096305883367 0.0011295543106797 89.12378640776699 289.9466019417476 -0.5560150541745451 0.5719206873770124 28.252188114125456 26.180424449873424 0.6383011650719348 0.3021618291173143 0.9529192081371952 0.2384060180052518 0.0009846242993225 6.221855864640624e-05 +Caspase-like domain superfamily [IPR029030] 2 5 2.4874236498899984 0.0128672069430639 1.0429042904290429 2.254125412541254 -0.1822739771754456 0.4061856906844451 0.8796230895210494 1.190490848145931 1.5263000234628414 0.3357787389369007 1.0 1.0 0.0007272762906085 0.0053637976870067 +Protein kinase-like domain superfamily [IPR011009] 40 84 2.477060628521199 0.0132469397385674 20.41990291262136 70.37378640776699 -0.1027148677914017 0.6421551859523025 9.026438620260558 14.97574389072516 0.8497696380066302 0.3174331396666366 0.2570067626682825 0.1401315800405851 0.0337447662186481 0.0343508837285022 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 5 7 2.428415899760516 0.0151649417818369 2.3592233009708736 5.065533980582524 -0.0414779785270424 0.5135274314368297 1.4687975990686668 1.3840549880732227 1.041360968799742 0.3265718594638703 0.0607401038440192 0.0066572828402184 8.971938182982207e-06 1.665940864684324e-05 +HECT, E3 ligase catalytic domain [IPR035983] 4 10 2.307806896040579 0.0210098792090507 3.5364077669902914 8.95631067961165 -0.082655155531572 0.5172769027958292 2.244980314039549 2.0498718834184824 0.9922663464789628 0.3114818745947644 0.0068317681715133 0.0255840399150975 0.0003539240376489 0.0075753503172145 +Cyclin-like superfamily [IPR036915] 3 5 2.2567765969868367 0.0240220378052291 1.5407407407407407 3.4098765432098768 0.0739811189971918 0.5422801432539582 1.1743953293396394 1.6177720496137604 1.0716835988943594 0.3150272661941172 0.134742527043449 0.2518545844225215 0.1648346062433529 0.1781060735503897 +Translation protein SH3-like domain superfamily [IPR008991] 6 9 2.2396639996184726 0.0251127444056229 5.533980582524272 10.04126213592233 -0.6036748352654394 0.3877498786779733 2.367110950515448 0.8189185143996353 1.121702761763535 0.314654675983089 1.0 0.0066572828402184 0.0033939033653995 8.329520797212374e-07 +PIN-like domain superfamily [IPR029060] 2 5 2.2272644682005613 0.0259296037485072 1.3737864077669903 4.351941747572815 0.2459635379058174 0.3786833021283934 1.2982782597791782 0.7001533233644651 1.2270454665485009 0.2945172382220569 1.0 1.0 0.0033939033653995 0.0228394808772788 +Ribosomal protein L2, domain 2 [IPR014722] 7 12 2.1708784324001744 0.0299403630637635 5.737864077669903 11.25 -0.6609982231548526 0.3931826402266836 2.497420669599456 1.4740884957165508 1.0649776696651303 0.3158800401167336 1.0 0.0113213926532688 0.0630532374058985 4.962609141310809e-07 +Acyl-CoA N-acyltransferase [IPR016181] 4 8 2.078757352073356 0.0376396586105094 2.5849514563106797 9.300970873786408 0.3026886570520987 0.4824772135374048 1.9004513382103856 1.21347572256257 0.9257996515560925 0.2786861297784554 1.0 0.2445730022705269 0.510851629797044 0.4165733999734724 +Protein-tyrosine phosphatase-like [IPR029021] 10 13 2.029482733550505 0.0424091458961251 3.3762135922330097 9.74757281553398 -0.2401801536762176 0.5610541986052188 2.114838292381251 2.9427166848706903 0.8969489539760671 0.31219801913805 1.0 0.1163398228410075 0.016092475953857 0.0091218528537202 +SNF2-like, N-terminal domain superfamily [IPR038718] 13 18 1.993487100957407 0.0462081346183014 6.303398058252427 14.475728155339803 -0.5651620597123135 0.4591559356456904 3.369291375872709 3.0188555029116086 0.984948378295502 0.3251280211427139 1.0 0.0376249374527164 0.0001038396922648 1.482058094111503e-05 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..53ca1ec233f07591431d1baee49bccefcf739661 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 997, + "title": "Average number of proteins per term", + "value": 5.023069207622869 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7944587725c3eb78ff5e20a169b0cad0d443d36b --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9b352a5f47a53d2872a62e3a231865f28c4d474a --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,195 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Armadillo-type fold [IPR016024] 0.5582478264635784 7.3260422040752 2.3704916824391577e-13 2.3633901771128406e-10 2.3633901773918403e-10 169 Q70CQ2,Q14185,O43592,Q5VW36,Q13535,Q86Y56,Q9Y6D5,P42695,Q6AI08,Q9HAV4,Q7Z4Q2,Q5VYK3,P42858,Q14997,O94822,O00443,Q9UBB6,Q08AM6,O75691,Q92616,Q9Y613,O14617,Q04637,Q8WTT2,Q9BTW9,O95373,Q9Y263,Q8TCG1,Q8TF05,Q92973,P42356,Q9H4A4,Q69YN4,O75165,Q9Y4A5,Q92600,Q9UBF2,Q15021,P55060,Q9Y5L0,Q5C9Z4,P78527,Q5T4S7,Q7Z6Z7,O94973,O43432,O00629,Q13315,Q9ULT8,Q9BPX3,Q13200,Q6PJG6,Q9NTI5,Q6NXR4,Q92538,Q7Z5K2,Q14738,O75155,Q93008,P21359,P53618,Q9UI26,Q9NVU7,Q14999,Q9NPQ8,Q9UIA9,Q96P70,Q29RF7,P50851,Q7Z460,Q7Z3U7,O15397,Q13144,Q86VP6,O14980,O14981,Q9Y678,P42345,O00203,Q00610,Q5JTH9,Q5SRE5,Q14008,Q99570,Q8TEX9,Q9HAU5 86 +Armadillo-like helical [IPR011989] 0.5462287994985121 6.030112409419967 1.6384567345316332e-09 1.63354003243531e-06 8.167706826625192e-07 114 Q9Y263,O43592,Q8TCG1,Q8TF05,O15397,Q92973,P53618,Q13535,Q9UI26,Q86Y56,O75165,Q9Y4A5,Q9Y6D5,Q92600,P42695,Q9UBF2,Q86VP6,Q6AI08,O14980,Q15021,Q9HAV4,Q7Z4Q2,O14981,Q5VYK3,P55060,P42858,Q9Y5L0,Q14997,Q9NPQ8,Q9UIA9,O94822,Q9Y678,P78527,P42345,Q96P70,O00203,Q29RF7,O94973,Q08AM6,Q5JTH9,O00629,Q9ULT8,Q92616,Q9Y613,Q9BPX3,Q13200,Q14008,O14617,Q14738,Q6PJG6,Q9NTI5,P50851,Q7Z460,Q99570,Q7Z5K2,Q8TEX9,Q9BTW9,O95373,O75155 59 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.9573261712921504 3.259938821924765 0.0011143624775535 0.6709807073146583 0.0186002900940787 2 O00443 1 +P-loop containing nucleoside triphosphate hydrolase [IPR027417] 0.2849775239401697 3.256096305883367 0.0011295543106797 0.6759320813646494 0.0186002900940787 306 Q9UM54,P46063,P51532,Q12873,P38935,Q9GZR7,Q9NRZ9,Q6P158,Q9Y6B6,Q92499,Q96QE3,Q9NUQ8,Q7Z478,Q9Y620,Q9Y295,Q8IX18,Q9H4L7,Q9HCK8,Q8NE71,Q05639,Q14147,P60953,A3KN83,P35251,P46940,Q7Z7L1,Q86WJ1,Q8TCY9,Q14527,Q9Y5Y2,P33992,O00178,P13639,Q96L91,Q03518,Q9Y496,Q14204,Q7L014,Q92620,Q9HCE1,Q9H4M9,P36915,O00429,O43237,P33993,Q15477,Q14562,O60231,P35580,O14646,Q9BW19,O43913,Q8WVC6,Q9BUJ2,O60841,Q9Y450,P42694,O43795,Q8IY37,P84085,O43933,P20585,P54132,Q2NKX8,Q5SY16,Q9P2D1,Q96GQ7,Q99661,P52701,Q15058,Q14692,Q14839,Q9NUL7,Q8N3C0,P61586,P18074,Q99741,Q9Y3D8,Q92614,Q9ULI0,Q96Q89,Q9NTJ3,Q14240,O60333,Q15382,Q6PL18,Q15019,Q9H223,P04183,O14981,P17812,P26196,O94832,P50570,Q9BVQ7,Q9UG63,Q9UNY4,P35579,Q5T9A4,Q9H6S0 100 +F-box-like domain superfamily [IPR036047] 0.9079883161265668 3.0257703438609287 0.0024800059059018 0.9158906007737354 0.0209849323338402 3 Q9Y3I1 1 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.9056716417910472 3.0155069051635737 0.0025655009724696 0.9227795620688 0.0210731352723672 3 P61313,P62847 2 +Dedicator of cytokinesis, C-terminal, lobe C [IPR043162] 0.9003282602208236 3.011477694748019 0.0025997950235718 0.9253817988510634 0.0210731352723672 2 Q14185 1 +Dedicator of cytokinesis, C-terminal, lobe A [IPR043161] 0.9003282602208236 3.011477694748019 0.0025997950235718 0.9253817988510634 0.0210731352723672 2 Q14185 1 +Tautomerase/MIF superfamily [IPR014347] 0.8737690241718874 2.8930903316517553 0.0038147156835786 0.977863871638199 0.0226801459853336 2 P30046 1 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.8680990749030086 2.8675960417403994 0.004136032490805 0.9839520747023996 0.0239483187841369 2 Q9UBF2 1 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9892637423331307 0.0247204055657475 3 P20585 1 +MutS, connector domain superfamily [IPR036678] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9892637423331307 0.0247204055657475 3 P20585 1 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9892637423331307 0.0247204055657475 3 P20585 1 +HR1 repeat superfamily [IPR036274] 0.8570575947478358 2.8177240904489955 0.0048365351369787 0.9920431669433624 0.0252206647096042 2 Q16513 1 +Nucleoside diphosphate kinase-like domain superfamily [IPR036850] 0.8567591763652582 2.816372053583634 0.0048569384395626 0.9922041628083098 0.0252206647096042 2 P15531 1 +Methylglyoxal synthase-like domain superfamily [IPR036914] 0.854968666069828 2.808255235897178 0.0049810731116037 0.993115890167802 0.0253392041522954 2 P27708 1 +BRK domain superfamily [IPR037259] 0.8432835820895556 2.734265603585516 0.0062519590643606 0.998074885144554 0.0286549915761361 3 Q9P2D1,Q9HCK8 2 +DNA polymerase family B, thumb domain [IPR042087] 0.841829786319154 2.727598793112745 0.006379715052978 0.998306489943108 0.0286549915761361 3 Q07864 1 +DNA polymerase, palm domain superfamily [IPR023211] 0.841829786319154 2.727598793112745 0.006379715052978 0.998306489943108 0.0286549915761361 3 Q07864 1 +Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035] 0.8188600417785693 2.642871032977302 0.0082206340868946 0.999733422619819 0.0324977881789361 2 P07814 1 +Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056] 0.8188600417785693 2.642871032977302 0.0082206340868946 0.999733422619819 0.0324977881789361 2 P07814 1 +PurM-like, C-terminal domain superfamily [IPR036676] 0.8159620777991429 2.608097593597647 0.0091046992061381 0.9998904315499376 0.0345147722757402 3 O15067 1 +PurM-like, N-terminal domain superfamily [IPR036921] 0.8159620777991429 2.608097593597647 0.0091046992061381 0.9998904315499376 0.0345147722757402 3 O15067 1 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.803939122649951 2.573578480635401 0.010065281646816 0.9999583383804656 0.0366244007367723 2 Q96CW5 1 +Ribosomal protein L37ae/L37e [IPR011331] 0.7955834079379225 2.5345294546485917 0.0112598460525039 0.99998749956203 0.0390781967252198 2 P61513 1 +Ribosomal L18e/L15P superfamily [IPR036227] 0.7967977821808943 2.51848635775526 0.0117860449181002 0.999992647592881 0.0402420780251572 3 P46776 1 +Sec7 domain superfamily [IPR035999] 0.7921078842338598 2.49641623971699 0.012545529324365 0.9999965839110664 0.0408754664587971 3 Q9Y6D5 1 +Sec7, C-terminal domain superfamily [IPR023394] 0.7921078842338598 2.49641623971699 0.012545529324365 0.9999965839110664 0.0408754664587971 3 Q9Y6D5 1 +Caspase-like domain superfamily [IPR029030] 0.7989090461472421 2.4874236498899984 0.0128672069430639 0.99999753138767 0.0413825978136606 5 P42574,P55212 2 +Protein kinase-like domain superfamily [IPR011009] 0.549021803881111 2.477060628521199 0.0132469397385674 0.999998317881758 0.0424668775541858 84 P36507,P49841,P68400,Q13523,O75116,P31751,P42356,Q00535,Q13535,Q9Y4A5,Q9HA64,P78362,O14965,P17612,Q9NYV4,Q00534,P78527,Q9H2G2,P42345,O00443,Q15418,Q7KZI7,P19784,Q16513,O14976,Q13315,P11802,Q96SB4,O15111,Q13418,O96017,Q16512,Q13555,Q13464,P35790,P28482,Q99986,P49761,Q99570,P53350 40 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.7940880828875694 2.428415899760516 0.0151649417818369 0.9999997582259202 0.046810014800288 7 O00443,P42356,Q13535,Q13315,P78527 5 +DNA/RNA polymerase superfamily [IPR043502] 0.7791193912813805 2.41370047043984 0.0157914381507287 0.9999998718031592 0.0474218790249292 4 Q07864 1 +Arrestin-like, C-terminal [IPR014752] 0.7564905998209353 2.3494878799537595 0.0187992561293599 0.9999999939382898 0.0524573306465021 2 P49407 1 +HECT, E3 ligase catalytic domain [IPR035983] 0.7786741455171677 2.307806896040579 0.0210098792090507 0.9999999993603028 0.0567665300038579 10 O95071,Q9UII4,Q15386,Q7Z6Z7 4 +Cyclin-like superfamily [IPR036915] 0.7507871783358013 2.2567765969868367 0.0240220378052291 0.9999999999703728 0.0617267311644677 5 O75909,O95067,P14635 3 +SGNH hydrolase superfamily [IPR036514] 0.7356013130408694 2.2490267197291423 0.0245107961524635 0.9999999999820196 0.0626400022182436 2 Q2TAA2 1 +Translation protein SH3-like domain superfamily [IPR008991] 0.7617110091675442 2.2396639996184726 0.0251127444056229 0.9999999999902832 0.0637084126524327 9 P50914,P61353,Q02878,P61254,P46778,P62917 6 +PIN-like domain superfamily [IPR029060] 0.7447141813596616 2.2272644682005613 0.0259296037485072 0.9999999999957871 0.0651179217563268 5 Q9Y2L1,Q96EK7 2 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.7305282005371516 2.2244636892985152 0.026117262906526 0.9999999999965234 0.0654125512881829 2 O43924 1 +PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946] 0.7281408534765619 2.212882393292079 0.026905754857927 0.9999999999984496 0.0663986079043396 2 Q9NZC3 1 +Zinc finger, NHR/GATA-type [IPR013088] 0.7297667279047266 2.1978046473055985 0.0279630301329849 0.9999999999994756 0.0683312280455539 3 P10589 1 +Myosin S1 fragment, N-terminal [IPR008989] 0.7324011756778932 2.188456563336876 0.0286363619645579 0.9999999999997372 0.0694658220892075 4 Q9UM54,P35579 2 +DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599] 0.7264554192657929 2.181673169469412 0.0291336624664673 0.9999999999998422 0.0700146825524978 3 P18858 1 +Ribosomal protein L2, domain 2 [IPR014722] 0.7565119123770621 2.1708784324001744 0.0299403630637635 0.9999999999999312 0.0707641768911459 12 Q14999,P50914,P61254,Q02878,P62701,Q92917,P62917 7 +Phosphofructokinase superfamily [IPR035966] 0.7226106659490537 2.1629092648762085 0.0305481590431688 0.9999999999999633 0.0711600807617742 3 P17858 1 +Zinc-binding ribosomal protein [IPR011332] 0.7211940298507502 2.155986429130323 0.0310847248504915 0.9999999999999788 0.071951785674117 3 P61513,P61927 2 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.7162041181736816 2.1547637411621317 0.031180326967318 0.9999999999999808 0.071951785674117 2 Q9UBT2 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.7258331481024582 2.078757352073356 0.0376396586105094 1.0 0.0833927547437287 8 Q9H9T3,Q9GZZ1,P30419,O95260 4 +Translation Initiation factor eIF- 4e-like [IPR023398] 0.6938227394807515 2.044851074841573 0.0408695426020817 1.0 0.0889671047473264 2 O60573 1 +Protein-tyrosine phosphatase-like [IPR029021] 0.7309626685445223 2.029482733550505 0.0424091458961251 1.0 0.0913538746625306 13 Q06124,O60942,P51452,Q99956,Q13614,Q9ULE6,O95248,Q12923,Q9UNI6,Q8NCE2 10 +ESCRT assembly domain [IPR037202] 0.6881527902118639 2.0168155242006227 0.0437147682697329 1.0 0.0923381863663639 2 Q99816 1 +SNF2-like, N-terminal domain superfamily [IPR038718] 0.7346973471976695 1.993487100957407 0.0462081346183014 1.0 0.0955798967104699 18 Q9NRZ9,O14981,O14646,Q96L91,Q14839,P51532,Q9H4L7,Q12873,Q86WJ1,Q9P2D1,Q14527,Q9UNY4,Q9HCK8 13 +Diaphanous, GTPase-binding domain superfamily [IPR044933] 0.6789018203521313 1.9709113273997452 0.0487340192487582 1.0 0.0993615893476726 2 O60610 1 +GHMP kinase, C-terminal domain superfamily [IPR036554] 0.6732318710832582 1.9426787674905848 0.0520549832014971 1.0 0.1056506424955556 2 P51570 1 +CAP Gly-rich domain superfamily [IPR036859] 0.6768672472275434 1.9369553133420736 0.0527508060622583 1.0 0.1060333742824023 3 Q99426 1 +WGR domain superfamily [IPR036930] 0.6699492688749487 1.9263001798486663 0.0540669029927352 1.0 0.1069113537227323 2 P09874 1 +Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616] 0.6699492688749487 1.9263001798486663 0.0540669029927352 1.0 0.1069113537227323 2 P09874 1 +Formin, FH2 domain superfamily [IPR042201] 0.6793072558972804 1.9260887988304407 0.0540932870075052 1.0 0.1069113537227323 4 Q9Y613,O60610,Q27J81 3 +AF1104-like superfamily [IPR036075] 0.6696508504923881 1.9248100125153569 0.0542531309277538 1.0 0.1069113537227323 2 Q9NVE7 1 +Six-hairpin glycosidase superfamily [IPR008928] 0.6790407776449123 1.9247557300755096 0.0542599247579764 1.0 0.1069113537227323 4 Q93100,P35573 2 +Calpain large subunit, domain III superfamily [IPR036213] 0.6636824828409351 1.894964900630568 0.0580970518814949 1.0 0.1131303920426766 2 P17655 1 +Gelsolin-like domain superfamily [IPR036180] 0.6665892627869254 1.8622960327112277 0.0625613743887463 1.0 0.1192640607404052 4 O95486,Q15436 2 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.6665892627869254 1.8622960327112277 0.0625613743887463 1.0 0.1192640607404052 4 O95486,Q15436 2 +Dynein light chain superfamily [IPR037177] 0.6571172784243453 1.8620446659348515 0.0625967945994796 1.0 0.1192640607404052 2 P63167 1 +WWE domain superfamily [IPR037197] 0.6617910447761269 1.8614375281828024 0.0626824150731919 1.0 0.1192640607404052 3 Q7Z6Z7,Q7Z2W4 2 +Kelch-type beta propeller [IPR015915] 0.6602463928583686 1.8303533882265213 0.067197112889735 1.0 0.1238109530485374 4 O60294 1 +R3H domain superfamily [IPR036867] 0.6588777239780501 1.8234499880214703 0.0682352651639297 1.0 0.1243703096315136 4 P38935 1 +Phosphoribosyltransferase-like [IPR029057] 0.6610878661087987 1.771128290770692 0.0765393704574552 1.0 0.1357824774841333 7 P00492,P07741,P11172,Q14558,O60256,P11908 6 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.6542401535863354 1.7556712390917455 0.0791445604359157 1.0 0.1384335557098386 6 Q9UBF2,Q10567,O94973,Q9Y678 4 +TBP domain superfamily [IPR012295] 0.6542401535863354 1.7556712390917455 0.0791445604359157 1.0 0.1384335557098386 6 Q9UBF2,Q10567,O94973,Q9Y678 4 +Ribokinase-like [IPR029056] 0.6368330722192417 1.735379421909262 0.082673622508816 1.0 0.1431000028494611 3 O00764 1 +eRF1, domain 2 superfamily [IPR042226] 0.6299612056102619 1.7249174211234233 0.084542355540695 1.0 0.1460809852236965 2 P62495 1 +Metal-dependent hydrolase [IPR032466] 0.6501128779162083 1.7152142067646834 0.0863059611175141 1.0 0.148356971093382 7 Q9BPU6,Q01433 2 +Actin-crosslinking [IPR008999] 0.6272754401671106 1.7112764170041803 0.0870300976958635 1.0 0.1491135316674494 2 Q14331 1 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.6319126409465009 1.7103846193930587 0.0871947732819689 1.0 0.1491135316674494 3 Q15436 1 +RNA-binding S4 domain superfamily [IPR036986] 0.6337433791700602 1.6960307797833418 0.0898800511374278 1.0 0.1531801897162658 4 P62701,P46781 2 +GAR domain superfamily [IPR036534] 0.6216054908982264 1.682435275350053 0.0924844659062504 1.0 0.1560186336861788 2 Q9UPN3 1 +Ubiquitin-activating enzyme [IPR035985] 0.6392389978483435 1.6596156663092636 0.0969917946612535 1.0 0.1621792262344 7 P22314,O95352,Q9UBT2,Q13564 4 +S15/NS1, RNA-binding [IPR009068] 0.6296051314927431 1.652081997691715 0.0985178362907839 1.0 0.1637038046365192 5 P62277,P07814 2 +Profilin superfamily [IPR036140] 0.607579826917332 1.6108519191081117 0.1072120017443478 1.0 0.1738054727465281 2 P07737 1 +ARFGAP/RecO-like zinc finger [IPR037278] 0.6010146225007396 1.5772364580574227 0.1147411270140723 1.0 0.183328371206779 2 Q8IYB5 1 +ArfGAP domain superfamily [IPR038508] 0.6010146225007396 1.5772364580574227 0.1147411270140723 1.0 0.183328371206779 2 Q8IYB5 1 +Chromo-like domain superfamily [IPR016197] 0.6276048794110254 1.5626210095184556 0.1181417636408577 1.0 0.1875594559712343 9 Q9P2D1,Q14839,O14646,Q9HCK8 4 +Inorganic pyrophosphatase superfamily [IPR036649] 0.5932557445538575 1.5374287707978211 0.1241883454041414 1.0 0.1937649145038013 2 Q9H2U2 1 +Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.2040387738659936 2 P22314 1 +Ubiquitin-activating enzyme E1, SCCH domain [IPR042063] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.2040387738659936 2 P22314 1 +Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302] 0.5854968666069755 1.4975423591595978 0.1342521922327901 1.0 0.2040387738659936 2 P22314 1 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.6496736531819534 1.4944285939174748 0.1350636325484915 1.0 0.204959576333099 39 Q8NEC7,Q96FX7,Q86W50,P49327,P26358,O60294,Q9BV86,Q9UBP6,Q9UET6,O43709,P19623,P46087,Q8TEA1,Q08J23,Q96P11,Q99873,Q14353,Q8N1G2,Q8IY81,O60678,Q7Z2T5,O14744,Q7L2J0,Q7Z4G4,Q8WVM0 25 +HIT-like superfamily [IPR036265] 0.5877991918954002 1.4845527398275584 0.1376623425620469 1.0 0.2078884256243834 3 Q96C86 1 +Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449] 0.5856716417910515 1.473595981786325 0.1405904038990528 1.0 0.2110973383845718 3 P22314,Q9UBT2 2 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.6010608817530683 1.443784593106437 0.1487995771610961 1.0 0.2207721097373151 8 P04350,Q13885,Q9BUK6,Q9BUF5 4 +F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276] 0.5770773901637334 1.4292923381633431 0.1529202272456959 1.0 0.2235505374838107 3 P47755 1 +F-actin-capping protein subunit alpha/beta [IPR037282] 0.5770773901637334 1.4292923381633431 0.1529202272456959 1.0 0.2235505374838107 3 P47755 1 +MAGE homology domain, winged helix WH1 motif [IPR041898] 0.5721785776566513 1.404011618022005 0.1603153899769058 1.0 0.2306906474826985 3 Q9Y5V3 1 +MAGE homology domain, winged helix WH2 motif [IPR041899] 0.5721785776566513 1.404011618022005 0.1603153899769058 1.0 0.2306906474826985 3 Q9Y5V3 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.5763924696866571 1.4016276012755398 0.161026480330015 1.0 0.231330548831448 4 Q9BXS5,P48444 2 +Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059] 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.2327515087032208 2 Q00653 1 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.5625186511489036 1.3790532432726292 0.1678783384496909 1.0 0.2397918387311487 2 Q5T440 1 +Cullin homology domain superfamily [IPR036317] 0.584652330638329 1.3782615919613728 0.1681225369852104 1.0 0.2397970949560154 7 Q13618,Q14999,Q13616 3 +Metal-dependent hydrolase, composite domain superfamily [IPR011059] 0.5760189925144992 1.3764096733571969 0.1686948348034032 1.0 0.2402696432842757 5 Q9BPU6 1 +SMAD/FHA domain superfamily [IPR008984] 0.5987234043684925 1.3616201202015576 0.1733178021621433 1.0 0.2444099699514241 12 O96017,Q15058,Q14676,P55196,P85037,Q5SW79,O60333 7 +Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591] 0.5553566099671647 1.342044192109222 0.1795816672627257 1.0 0.2515626750553356 2 P08865 1 +SH2 domain superfamily [IPR036860] 0.5914547257306533 1.3401639786869617 0.1801920396567506 1.0 0.2515626750553356 11 Q06124,P22681,O15357,P46109,P19174,P40763 6 +Ribonuclease H superfamily [IPR036397] 0.6003485129025457 1.33949820540101 0.1804085382794031 1.0 0.2515626750553356 14 Q9GZR2,Q9H9L3,Q07864,P28340 4 +Initiation factor 2B-like, C-terminal [IPR042529] 0.5573134328358286 1.3272151719061134 0.1844375149949448 1.0 0.2557499338664256 3 P49770,Q14232 2 +Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091] 0.5774639130154521 1.3215007469735376 0.1863344536238012 1.0 0.2576635925976834 8 O95071,O75592,Q9UII4 3 +Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041] 0.5765031042824442 1.3165193480108004 0.1879997888285605 1.0 0.2596063565956715 8 Q9UBF2,O94973,O95782,Q10567,Q9Y678 5 +EB1, C-terminal domain superfamily [IPR036133] 0.5472993136377103 1.3003872891797508 0.1934682641813276 1.0 0.2645923997102656 2 Q15555 1 +Papain-like cysteine peptidase superfamily [IPR038765] 0.6107564587559066 1.279191927525518 0.2008294778409496 1.0 0.272788813906576 25 Q70CQ2,Q9UPT9,Q86UV5,Q9Y4P1,Q93008,P40818,Q01804,Q96RU2,Q96FW1 9 +Rhodanese-like domain superfamily [IPR036873] 0.5560061904439745 1.2503584762707365 0.21116862594537 1.0 0.2825974766007166 6 P30307,Q99956 2 +MRG, C-terminal domain superfamily [IPR038217] 0.5371530886302491 1.2479233250681243 0.2120591378045342 1.0 0.2830293981139499 2 Q15014 1 +Zinc finger, CCCH-type superfamily [IPR036855] 0.5695778541473818 1.243647867217455 0.2136291908225351 1.0 0.2836062626498902 10 Q8IWR0,Q6P158 2 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2930274667237086 7 P04350,Q13885,Q9BUF5 3 +Tubulin/FtsZ, C-terminal [IPR008280] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2930274667237086 7 P04350,Q13885,Q9BUF5 3 +Tubulin, C-terminal [IPR023123] 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2930274667237086 7 P04350,Q13885,Q9BUF5 3 +Oxysterol-binding protein superfamily [IPR037239] 0.5491779532515481 1.2150684642992582 0.2243399801128189 1.0 0.2938099089427337 6 Q9BZF3 1 +Galactose-binding-like domain superfamily [IPR008979] 0.5634695797635116 1.1945091532679453 0.2322788623726492 1.0 0.3019322370085154 11 O75592,Q14999,O43396,Q9ULT8,Q9UL63 5 +Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008] 0.5413588615496538 1.1746993393956675 0.2401150237646545 1.0 0.311650650146206 6 P26640,P41252 2 +Endonuclease/exonuclease/phosphatase superfamily [IPR036691] 0.5404828795453247 1.1701803619478093 0.2419283939672138 1.0 0.3132501412796263 6 Q01968,P27695 2 +Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103] 0.5171590569978994 1.1446585994358836 0.2523506076234609 1.0 0.3238012301165902 2 P49591 1 +Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978] 0.5171590569978994 1.1446585994358836 0.2523506076234609 1.0 0.3238012301165902 2 P49591 1 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.566303122868433 1.1073012546269136 0.2681637020915903 1.0 0.3405849821468988 18 P49721,P28072,P60900,P20618,P25787,P28074,P28066,P49720,P08243,P25786,Q06210,P25789 12 +Kinesin motor domain superfamily [IPR036961] 0.5602942821641943 1.0326705815868915 0.301758085171218 1.0 0.3760660136446305 22 Q9UM54,O43795,Q15058,O94832,P35580,Q9BW19,P35579,Q92614,Q9Y496,Q96Q89,O00139,Q99661,O60333 13 +Anticodon-binding domain superfamily [IPR036621] 0.5009137235157943 0.9896635328707444 0.322338605051963 1.0 0.3987240561250708 5 P07814 1 +SMCs flexible hinge superfamily [IPR036277] 0.5002323262689812 0.986196679432245 0.3240366084354822 1.0 0.3993158932298093 5 Q9NTJ3,A6NHR9 2 +Histone deacetylase domain superfamily [IPR037138] 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.3993158932298093 2 Q13547 1 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.5140252474311424 0.9755603549880236 0.3292823788327965 1.0 0.4048021352605402 9 Q13618,Q13616,Q9UID3 3 +PPM-type phosphatase domain superfamily [IPR036457] 0.4882054344580557 0.9480161083037252 0.3431212537925143 1.0 0.4197446503449531 4 P49593,O15355,Q9H0C8 3 +Chloride channel, core [IPR014743] 0.4765741569680598 0.936892202781896 0.3488140104023292 1.0 0.4256640983734666 2 P51790 1 +TGS-like [IPR012676] 0.4875780611616304 0.9001079557200667 0.3680628026350028 1.0 0.4469654253679632 6 P55039,P26639,Q9Y295 3 +Ribonuclease H-like superfamily [IPR012337] 0.5216708425253063 0.8889396635146004 0.3740355074703243 1.0 0.4536659378928386 17 Q9GZR2,Q9H9L3,Q07864,P28340 4 +PUA-like superfamily [IPR015947] 0.488346076899163 0.8462014126684955 0.3974403940103936 1.0 0.4785604744303895 9 Q9ULC4,Q8TEA1 2 +WD40-repeat-containing domain superfamily [IPR036322] 0.2349836384830347 0.8429021596459119 0.3992831656122095 1.0 0.4801994163032242 108 P18583,P31146,Q9Y263,P57737,Q9HAD4,Q96BP3,Q8TEQ6,Q9HC35,Q9GZS3,P57081,Q9NVX2,P50748,Q9UFC0,P55735,Q9Y484,O94979,Q9BY44,Q5TAQ9,P63151,Q04727,O94967,Q5T4S7,P61962,P53621,Q9BZH6,Q9UJX5,Q9H7D7,O75717,O76071,O60271,P63244,P43034,P50851,Q99570,Q5JSH3,Q9Y2X0,Q9Y3F4,Q8WUA4,Q15334,Q6UXN9,O43684 41 +Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001] 0.470927452815232 0.8387193355083502 0.4016268254165309 1.0 0.4818555294106876 5 Q05639,O00178 2 +BRO1 domain superfamily [IPR038499] 0.453297523127415 0.8200968641537962 0.4121608897533304 1.0 0.4933066111453426 2 Q5VW32 1 +Rho GTPase activation protein [IPR008936] 0.4702294255392676 0.7395297543121928 0.4595853789753437 1.0 0.54548407480764 10 P46940,P21359 2 +Nucleotidyltransferase superfamily [IPR043519] 0.4613449621131081 0.7319692320528003 0.4641873475653466 1.0 0.550291064830738 8 Q5TAX3,P51003,Q96SI9,Q9NVV4,Q96Q11 5 +Creatinase/aminopeptidase-like [IPR036005] 0.4446635974282614 0.670701256345305 0.5024108623464765 1.0 0.5886059104106193 7 Q9NQW7,P50579,Q9Y5B9,Q9UQ80 4 +Metallo-dependent phosphatase-like [IPR029052] 0.4450442935622027 0.654337153098493 0.5128946145370736 1.0 0.5987774364092066 8 Q9UBQ0,Q08209,P62136,O00743 4 +Nucleic acid-binding, OB-fold [IPR012340] 0.4990405471446059 0.6531170702105557 0.5136808081743396 1.0 0.598993878069961 44 P49917,O60942,P67809,P62266,P35244,P18858,Q9Y2L1,O43776,P62280,Q9Y2V2,P62917 11 +RuvA domain 2-like [IPR010994] 0.4244913402709202 0.6359228673781887 0.5248266972082598 1.0 0.6098510689005071 4 Q7KZ85 1 +Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080] 0.4473656989454525 0.5993915093945997 0.548911837592829 1.0 0.6341426443569531 12 Q9P2J5,P26640,P54136,P41252 4 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.4037600716204089 0.5829388314397551 0.5599344786841418 1.0 0.6453811274544387 2 P15289 1 +TFIIS/LEDGF domain superfamily [IPR035441] 0.416446076369228 0.5413304535594197 0.588279833545194 1.0 0.6740520977754908 7 Q14241 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.4192793599458885 0.5368333361958211 0.5913827423960982 1.0 0.6757475239428137 8 Q6XZF7,Q9H8V3,Q92974 3 +BAG domain superfamily [IPR036533] 0.3912264995523657 0.526584584863955 0.5984820991056878 1.0 0.6805352198289885 2 Q9UL15 1 +Ubiquitin-conjugating enzyme/RWD-like [IPR016135] 0.4285066574262465 0.5150705862353328 0.606503695888311 1.0 0.6876313817712479 12 Q9NR09,P49427 2 +Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864] 0.4379546076861228 0.5028151681367404 0.6150942283222989 1.0 0.6952935891579728 16 P26639,P07814,P50747,O43776,Q9NSD9 5 +Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163] 0.3893011977887953 0.442155662362215 0.6583765676542053 1.0 0.737529705563194 6 P26639 1 +Histidine kinase/HSP90-like ATPase superfamily [IPR036890] 0.4019309914926164 0.417885848553466 0.6760305796519444 1.0 0.7530754054893727 11 Q9NZJ4 1 +Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866] 0.3819676769102597 0.4123975303352131 0.6800480730307901 1.0 0.7541801210363711 6 P78559,Q9NV88 2 +AMP-binding enzyme, C-terminal domain superfamily [IPR045851] 0.3792588164973015 0.3861745958208349 0.699367366818108 1.0 0.7747436274640597 7 O14975,Q6P1M0,Q4G176,Q9P265,Q96CM8,Q86V21 6 +BRCT domain superfamily [IPR036420] 0.4037667984857593 0.3748293417113027 0.7077873910231998 1.0 0.783200919922453 15 P35251,Q92547,P09874 3 +ANL, N-terminal domain [IPR042099] 0.3793721973094284 0.3718830394053 0.7099799335511547 1.0 0.7838870362685507 8 O14975,Q6P1M0,P33121,Q4G176,O95573,Q9P265,Q86V21 7 +Plakin repeat superfamily [IPR035915] 0.3646395833620863 0.3614737701601906 0.7177453096935467 1.0 0.7880969975379581 5 P58107,Q9UPN3 2 +C2 domain superfamily [IPR035892] 0.4094040622697546 0.3452108927867276 0.7299358303006411 1.0 0.7968805953341251 20 Q16512,Q14185,O00443,Q96N67,Q8N3C0,Q16513 6 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.3467621605490896 0.3444066538170021 0.7305404855921669 1.0 0.7968805953341251 2 Q15392 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.3467621605490896 0.3444066538170021 0.7305404855921669 1.0 0.7968805953341251 2 Q15392 1 +PX domain superfamily [IPR036871] 0.3794214161068355 0.3198917879971297 0.7490503632782677 1.0 0.8143982684715735 12 O00443,A1X283,Q9Y5X3,Q53T59,O60493 5 +CRAL-TRIO lipid binding domain superfamily [IPR036865] 0.3525935756581859 0.3172668731691952 0.7510411112702498 1.0 0.8156731894732452 5 P21359 1 +RNA polymerase Rpb2, domain 2 superfamily [IPR037034] 0.3339301700984794 0.2981871249888645 0.7655603478440485 1.0 0.8287336230190189 2 P30876 1 +Translation protein, beta-barrel domain superfamily [IPR009000] 0.3918116372470595 0.2750989864558397 0.7832401902428494 1.0 0.8435153989152592 21 O00178,Q05639,P13639,Q9BTE6,P39023,O60841,Q96HR8 7 +Ribosomal protein S11 superfamily [IPR036967] 0.3270665472993151 0.2748316300723444 0.7834455961840823 1.0 0.8435153989152592 2 P62263 1 +Beta-grasp domain superfamily [IPR012675] 0.3418188070691537 0.2539449805697594 0.79953806404813 1.0 0.8599131066407613 7 P55039,P26639,Q9Y295 3 +HSP40/DnaJ peptide-binding [IPR008971] 0.3315094731115741 0.2468716933057943 0.805007523861895 1.0 0.8648626091490402 5 P31689,Q9UBS4 2 +PH-like domain superfamily [IPR011993] 0.3818755009359559 0.2277058516276995 0.8198749229979472 1.0 0.8751769788318559 62 O75116,Q13614,P31751,P19174,P21359,Q12923,Q6DN90,Q9HCM4,P35241,P22059,Q08945,O14654,Q9H8V3,P50570,O95248,Q14155,O60333,Q13464,P50851,Q8NC96,Q92974,Q9BZF3,Q9Y5B9,O00401,Q9Y217 25 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.3393739134655498 0.2135777838438149 0.8308763255711449 1.0 0.8858425019631506 10 Q12800,Q9Y3Z3,Q6SZW1,O15357 4 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.3704049096827694 0.1968207721533874 0.843967795234585 1.0 0.897053189604351 23 O15084,P42771,Q8IWZ3,Q9ULT8,Q9P2R3,Q6W2J9,Q9H6S0 7 +Aldolase-type TIM barrel [IPR013785] 0.3519938951603573 0.1952299553836094 0.845212929229251 1.0 0.897419904623603 16 Q9NR45,P04075,Q9NZB8,P43490,P09972,Q6P1R4,P11172,Q9NX74,Q9P2T1,P20839 10 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.2843179975950031 0.1897170982974837 0.8495308216381008 1.0 0.8999447060884126 87 Q96EK5,Q14CX7,P42345,Q8IWR0,O00170,Q7L5D6,O75153,O76094,Q00610,O15091,Q6PGP7,Q15008,Q13535,Q15785,Q15020,Q9BQ70 16 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 0.3595355481235995 0.1894176610018381 0.8497654835440702 1.0 0.8999447060884126 67 O75925,Q96EP0,Q9UPT9,O75592,Q7Z3T8,Q96T51,P22681,Q14839,Q8IWS0,Q12873,Q9P2R3,O94822,Q9Y314,Q14527,P29375,Q14258 16 +NTF2-like domain superfamily [IPR032710] 0.3167222391749779 0.1819127682793969 0.855651184051466 1.0 0.9038998163387008 7 P61970 1 +Rudiment single hybrid motif [IPR011054] 0.3014639976097906 0.1539293942727035 0.8776654070294743 1.0 0.9181872096625244 6 P11498,Q96RQ3,Q13085,O00763,P22102 5 +UBA-like superfamily [IPR009060] 0.3386235320226742 0.1268890514812012 0.8990282122466196 1.0 0.936605149017638 22 Q7Z6Z7,P22681,Q96RU2,Q13501,Q6P158 5 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.3137862127762678 0.1046581342365535 0.9166470834940346 1.0 0.9519761898370338 17 Q8NEC7,O00299,P07814,Q9Y696,P26640,P26641 6 +Rossmann-like alpha/beta/alpha sandwich fold [IPR014729] 0.3326936273495626 0.0966407688890587 0.9230116791116588 1.0 0.9575885994529904 27 P47897,P49589,Q2VPK5,P07814,P41252,P08243,P23381,P54136,P49915,Q9P2J5,Q8NFF5,P26640 12 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 0.2990840017881069 0.0950323426880942 0.9242891374156744 1.0 0.9579171205856832 14 P60981,P53992,P60983,Q15436,Q9UJU6,Q9Y281,Q6IBS0,Q13045,O95486 9 +Chaperone J-domain superfamily [IPR036869] 0.3077152895579033 0.0861453862457342 0.931350844690501 1.0 0.9622350177786834 19 Q9NZJ4,Q9NVH1,Q9UBS4,O14976,Q5F1R6,O75165,P31689 7 +Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721] 0.2883810791525659 0.0791803220470411 0.9368891961756532 1.0 0.9669549985373976 14 P82675,P15880,P54277 3 +Bromodomain-like superfamily [IPR036427] 0.2889819229017348 0.0720440474647413 0.942566854093617 1.0 0.971557308011251 16 Q12830,P25440,Q6PL18,Q9UIG0,Q9ULI0,P51532,Q9UIF9 7 +Zinc finger C2H2 superfamily [IPR036236] 0.3066608102760887 0.0711261373445567 0.943297366253652 1.0 0.971557308011251 23 Q96JP5,Q9UKJ3,Q8IWR0,Q96KM6,O60678,Q5F1R6,Q9Y2X9 7 +WD40/YVTN repeat-like-containing domain superfamily [IPR015943] 0.1672128022037805 0.0614980892927541 0.9509625360514716 1.0 0.9765151795791936 116 P31146,Q9Y263,P57737,Q9HAD4,Q96BP3,Q8TEQ6,Q9HC35,Q9GZS3,P57081,Q9NVX2,Q9UFC0,P55735,Q9Y484,O95163,O94979,Q9BY44,Q5TAQ9,P63151,Q04727,O94967,P61962,P53621,Q9BZH6,Q9UJX5,Q9H7D7,O75717,O76071,O60271,P63244,P43034,P50851,Q99570,Q5JSH3,Q9Y2X0,Q9Y3F4,Q8WUA4,Q15334,Q6UXN9,O43684 39 +Zinc finger, FYVE/PHD-type [IPR011011] 0.3107888489102457 0.0613890314323038 0.9510493875339988 1.0 0.9765151795791936 29 Q9UPP1,Q7Z3T8,Q96T51,Q14839,Q9UIF9,Q12873,Q9P2R3,P29375 8 +p53-like transcription factor, DNA-binding [IPR008967] 0.2458273948489729 0.0570379459865684 0.9545149678029116 1.0 0.9776254153399906 7 P40763,Q8IWI9 2 +Pre-ATP-grasp domain superfamily [IPR016185] 0.2381373640520348 0.0468876361462422 0.9626027821830492 1.0 0.9823080591980552 8 P27708 1 +B30.2/SPRY domain superfamily [IPR043136] 0.2446509600400413 0.0438885631526236 0.9649932317996576 1.0 0.983740544073884 11 Q92499,Q14258,O15344,Q9BUJ2 4 +SH3-like domain superfamily [IPR036028] 0.2685792526206387 0.02547380407631 0.979677043023931 1.0 0.992631292604594 34 Q14185,Q9NZQ3,Q6XZF7,A1X283,Q9UQB8,Q9P0V3 6 +Winged helix-like DNA-binding domain superfamily [IPR036388] 0.2848809527638528 0.0254597452681079 0.9796882566929994 1.0 0.992631292604594 52 Q13616,Q9UQ80,P46063,P54132,P50579,Q4G0J3,Q9BUI4,Q14999,Q8N3C0,Q8NB78,Q99741,P62851,P16402,Q5JVF3,Q92522,Q6PKG0,P85037,Q13620,Q13618 19 +Immunoglobulin E-set [IPR014756] 0.2184726768814101 0.0205702275294806 0.983588490428848 1.0 0.9949711868064024 21 O75592,P49407 2 +Longin-like domain superfamily [IPR011012] 0.1816821310984759 0.0200624296512016 0.983993570903824 1.0 0.9949711868064024 12 P53680,P61923,Q9Y2T2,P56377,O15498,Q96CW1,P51809,O75396,Q9Y296,Q9BXS5,P48444 11 +Winged helix DNA-binding domain superfamily [IPR036390] 0.2590182297718438 0.016875471212772 0.9865359611176848 1.0 0.9955943269529796 51 Q13616,Q9UNS2,Q9UQ80,Q92522,Q6PKG0,P16402,P54132,P50579,Q8N3C0,Q15008,P85037,Q4G0J3,O43242,Q13620,Q13618,Q99741 16 +CH domain superfamily [IPR036872] 0.1888123367800308 0.0164543108816817 0.9868719517823346 1.0 0.9955943269529796 25 P46940 1 +K Homology domain, type 1 superfamily [IPR036612] 0.1578472639807617 0.0155346938044454 0.987605606175022 1.0 0.9955943269529796 27 Q9UNW9,Q9Y2W6,Q9NZI8,Q92667,Q96AE4,O00425,Q13601,Q96PU8,Q00341,Q8N9N2,Q9NQT5,Q15366,Q8IWZ3,Q15637,P61978,P51114,Q9Y6M1,Q06787,O75179,P51116,Q13868,Q07666,Q15365,Q92945,Q9NRX1,Q96I24 26 +Ubiquitin-like domain superfamily [IPR029071] 0.2155317313693533 0.0133980939751583 0.9893101874934456 1.0 0.996305310031278 45 Q9HCM4,Q96S82,Q9NZJ4,Q86UV5,Q8TAT6,P35241,P46379,Q9Y490,P55196,O00443,Q9UNN5,Q99426,Q12923,Q8NCF5,Q15370,Q96K76,Q9Y3I1 17 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4b1d2019cd0b31a41a61763bf11b4eb0ecf716c1 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMMECR1 domain superfamily [IPR036071]", "AMMECR1, N-terminal [IPR027485]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ASC domain superfamily [IPR037256]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioester hydrolase/BAAT, N-terminal [IPR042490]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha carbonic anhydrase domain superfamily [IPR036398]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin, N-terminal [IPR014753]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit VIb superfamily [IPR036549]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kazal domain superfamily [IPR036058]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin biosynthesis MoaE subunit superfamily [IPR036563]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PUB-like domain superfamily [IPR036339]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "ParB/Sulfiredoxin superfamily [IPR036086]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin kinase domain superfamily [IPR023465]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "RyR/IP3 receptor binding core, RIH domain superfamily [IPR035910]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Selenoprotein F/M, thioredoxin-like domain superfamily [IPR038219]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "T-box superfamily [IPR036960]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Tctex-1-like superfamily [IPR038586]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "Wiscott-Aldrich syndrome protein, C-terminal [IPR011026]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "AMMECR1", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANKRD46", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP5S", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATR", "ATXN10", "AURKA", "B3GAT3", "BABAM1", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT2", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CERS2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOPC", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS4", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPR2", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTI12", "L2HGDH", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED16", "MED21", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OVCA2", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMS", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX4", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM14C", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASL", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR47", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFP91", "ZFR", "ZFYVE16", "ZNF280C", "ZNF281", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZZZ3"], "leading_proteins": ["AACS", "AARSD1", "ABCF1", "ABCF2", "ABCF3", "ACACA", "ACACB", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "AFDN", "AGL", "AIP", "AK6", "AKAP1", "AKT2", "ALDOA", "ALDOC", "AMPD2", "ANAPC4", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD28", "AP1B1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "APRT", "ARCN1", "ARF5", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARRB1", "ARSA", "ASCC1", "ASCC3", "ASNS", "ATAD2", "ATAD2B", "ATAD3B", "ATAD5", "ATE1", "ATG4B", "ATG7", "ATM", "ATR", "AURKA", "BAG5", "BAG6", "BAIAP2", "BAZ1B", "BAZ2A", "BCOR", "BIRC6", "BLM", "BMS1", "BPTF", "BRAT1", "BRD2", "BROX", "BTAF1", "BUB3", "BUD23", "CAD", "CAMK2G", "CAND1", "CAND2", "CAPN2", "CAPZA2", "CARHSP1", "CARS", "CASP3", "CASP6", "CBL", "CCNB1", "CCNB2", "CCNK", "CDC25C", "CDC34", "CDC42", "CDC6", "CDK12", "CDK4", "CDK5", "CDK6", "CDKN2A", "CEP170", "CFL2", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHUK", "CIAO1", "CIP2A", "CKAP5", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLK3", "CLTC", "CLUH", "CMTR1", "CNOT9", "COPA", "COPB1", "COPG1", "COPG2", "COPS3", "COPZ1", "CORO1A", "CORO7", "CRKL", "CSE1L", "CSNK2A1", "CSNK2A2", "CTPS1", "CTU2", "CUL1", "CUL3", "CUL4B", "CUL7", "DBNL", "DCAF7", "DCAF8", "DCAKD", "DCPS", "DDT", "DDX1", "DDX24", "DDX27", "DDX28", "DDX46", "DDX6", "DHCR24", "DHX16", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DIAPH1", "DIP2B", "DIS3", "DNAAF5", "DNAJA1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC21", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DOCK7", "DPYSL5", "DRG1", "DRG2", "DSTN", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DYNC1H1", "DYNC1LI2", "DYNLL1", "ECT2", "EEF1A2", "EEF1G", "EEF2", "EHD1", "EHD4", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B5", "EIF4A2", "EIF4E2", "EIF4G1", "EIF4G3", "EIF5B", "ELOA", "ELOB", "ELP1", "ELP3", "EML4", "EP400", "EPB41L5", "EPPK1", "EPRS", "ERCC2", "ERCC6L", "ETF1", "EXOSC2", "EXOSC3", "FAF1", "FAM120B", "FARSB", "FASN", "FBXO7", "FHOD1", "FLAD1", "FLII", "FMR1", "FN3KRP", "FOCAD", "FOXK1", "FRG1", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FXR2", "GAK", "GALK1", "GAMT", "GART", "GBF1", "GCN1", "GDE1", "GEMIN5", "GET4", "GFPT1", "GMFB", "GMPR2", "GMPS", "GNL1", "GPATCH8", "GPKOW", "GSK3B", "GSTCD", "GTF3C2", "GTPBP1", "H1FX", "HBS1L", "HDAC1", "HDLBP", "HEATR3", "HEATR6", "HECTD1", "HELLS", "HELZ", "HERC5", "HIST1H1D", "HLCS", "HLTF", "HNRNPK", "HNRNPUL1", "HPRT1", "HS1BP3", "HTT", "HUWE1", "IAH1", "IARS", "IBA57", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGHMBP2", "ILK", "ILKAP", "IMPDH1", "INF2", "INPPL1", "INTS9", "IPO11", "IPO4", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQSEC1", "IRS4", "ISG20L2", "KDM1B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF14", "KIF1B", "KIF20B", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KNTC1", "KPNA4", "KRR1", "LARP1", "LARP7", "LARS", "LCMT2", "LIG1", "LIG4", "LLGL1", "LRBA", "LRWD1", "LTN1", "MACF1", "MAGED1", "MAP1A", "MAP2K2", "MAPK1", "MAPRE2", "MARK2", "MCCC1", "MCM5", "MCM7", "MCTS1", "MDC1", "MED16", "MEPCE", "METAP2", "METTL1", "METTL16", "MGA", "MID1", "MKLN1", "MOCS1", "MON2", "MORF4L2", "MOV10", "MRPS5", "MSH3", "MSH6", "MSTO1", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MYCBP2", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1D", "MYO6", "NAA25", "NAA50", "NAE1", "NAF1", "NAMPT", "NANS", "NARS", "NCAPD2", "NCAPD3", "NCAPG", "NCDN", "NCKIPSD", "NECAP1", "NF1", "NFATC2IP", "NFKB2", "NLE1", "NME1", "NMT1", "NOC3L", "NOL9", "NOM1", "NOP2", "NOSIP", "NOVA2", "NPLOC4", "NR2F1", "NSUN2", "NSUN5", "NSUN6", "NTMT1", "NUBP2", "NUP188", "NUTF2", "OCRL", "ORC5", "OSBP", "OSBPL6", "OTUB1", "OTUD4", "PA2G4", "PAFAH1B1", "PALD1", "PANK4", "PAPOLA", "PARP1", "PC", "PCBP1", "PCBP2", "PCID2", "PDE6D", "PDS5A", "PDS5B", "PDXK", "PEX1", "PFAS", "PFKL", "PFN1", "PHF6", "PHF8", "PHKB", "PI4KA", "PIAS1", "PIK3C2A", "PIK3R4", "PKN1", "PKN2", "PLAA", "PLCG1", "PLK1", "PMS1", "PNO1", "POLD1", "POLE", "POLR2B", "POLR3C", "PPA2", "PPM1F", "PPM1G", "PPP1CA", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP6C", "PPWD1", "PRKACA", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF4B", "PRPS2", "PRPSAP1", "PRPSAP2", "PSMA1", "PSMA2", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB5", "PSMB6", "PSMD2", "PSMD3", "PSMD6", "PSME4", "PTPN11", "PTPN13", "QARS", "QKI", "RACK1", "RAD54B", "RARS", "RDX", "RECQL", "REXO4", "RFC1", "RHEB", "RHOA", "RIC8A", "RNF31", "RNGTT", "RNPEP", "ROCK1", "ROCK2", "RPA3", "RPL14", "RPL15", "RPL21", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL37", "RPL37A", "RPL6", "RPL8", "RPS11", "RPS13", "RPS14", "RPS2", "RPS23", "RPS24", "RPS25", "RPS4X", "RPS6KA1", "RPS9", "RPSA", "RRP12", "RUFY1", "SACS", "SAMHD1", "SAR1B", "SARM1", "SARS", "SART3", "SBF1", "SBNO1", "SDAD1", "SEC13", "SEC22B", "SEC23A", "SEC24A", "SEC24C", "SEC31A", "SEPT2", "SF1", "SH3BP4", "SH3PXD2B", "SKIV2L", "SLC27A2", "SLC27A4", "SLFN11", "SLK", "SMAP1", "SMARCA4", "SMARCAD1", "SMC4", "SMCHD1", "SNX3", "SNX5", "SON", "SPAG9", "SPATA5L1", "SQSTM1", "SRM", "SRP72", "SRPK1", "SRPK2", "SSRP1", "STAT3", "STRAP", "STRBP", "SUPT16H", "SUPT6H", "TAP1", "TARS", "TBCB", "TBCD", "TCF25", "TDRKH", "TFB1M", "TFCP2", "TK1", "TLE4", "TLN1", "TNPO1", "TNPO3", "TOMM34", "TOPBP1", "TRAPPC4", "TRIM25", "TRMT11", "TRMT1L", "TRMT61A", "TRNT1", "TRRAP", "TSG101", "TTC37", "TTF2", "TTI2", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP3", "TWF2", "TXNL1", "UBA1", "UBA2", "UBE3C", "UBL7", "UBR4", "UBR5", "UMPS", "UPF2", "URGCP", "USP22", "USP28", "USP34", "USP47", "USP48", "USP8", "USP9X", "UTP20", "VAC14", "VAMP7", "VARS1", "VIRMA", "VPS29", "VPS51", "VRK1", "WAPL", "WARS", "WASL", "WDHD1", "WDR11", "WDR26", "WDR4", "WDR41", "WDR44", "WDR45", "WDR47", "WDR61", "WDR82", "XPNPEP1", "XPO1", "XPO5", "XPO7", "XPOT", "YBX1", "YKT6", "YTHDC2", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZFP91", "ZFYVE16", "ZNF281", "ZNF512B"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..63cf187acae1f17f229f7333d4f93afd03440dec --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:063e2336d39cda175cb2ec120e98883718d9ec02f2dbedeb1ab815c0ff3891bf +size 75222 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f850e8ccbeb125f10632b439d327a7123253647b --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8b007e75ee24e8f5b7707a811a57d53fe29411b2 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..911c0f98110fcfc0055bf4e7c9370c039a6363c6 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..64a0c6cd4eb371e391e1f54cf6236de0a684e67f --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "EIF5A", "FASN", "SLIT2"], "leading_proteins": []} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cb9261b8c2f4dea08a6e424ad6f37f5d6873a816 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "HEAT, type 2 [IPR021133]", "1": "Ankyrin repeat [IPR002110]", "2": "WD40 repeat [IPR001680]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..33d17e232d04142fe7f506b9f048a012df5f04ce --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8df606b1fa5c54a0bd14152b3267382d0588fb90227f3cd906b595c727b3a50f +size 127665 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..34e80deddd2a79d7ce97a66152e8be0874218a66 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ddbc5fe52df439c3bf455556696796b666cb62830c5849cd13b12af3c122213f +size 147002 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..7bf4c76559f141234b46445134e024ec3f911b1b --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ec0d1dd9ef000f2699968984d36336328a26a0e292d445de7edb1a018606546 +size 162719 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..500bbef7062aef6cff60ff32eaa528b3e005616f --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e45cf0431e2d1af4eada4ddb301e8e75ef45a1240c0c8098f63067135749b67f +size 86213 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0805aadbb3a30f3322d91be11376934a9312a6f4 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 77, + "title": "Average number of proteins per term", + "value": 5.9480519480519485 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f7c7ff6991e817589b4b0595dc127ad5c9244178 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..78d5c2adce0f3985a791e89613bca50ad6a49409 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Hexapeptide repeat [IPR001451] 0.869292748433302 2.8729697619932786 0.0040663303438197 0.2692952259213121 0.0216044752358594 2 Q13144 1 +Importin repeat 6 [IPR041389] 0.7582811101163847 2.3580476374108708 0.0183713352524512 0.7601515860814014 0.060897562762781 2 O00410 1 +Importin repeat 4 [IPR041653] 0.7582811101163847 2.3580476374108708 0.0183713352524512 0.7601515860814014 0.060897562762781 2 O00410 1 +HEAT, type 2 [IPR021133] 0.6839915890184123 1.7896371835715257 0.0735122567882546 0.9972032398204296 0.1715285991725942 13 Q14008,Q86Y56,Q99570,Q7Z460,Q13535,Q8TEX9,Q92616 7 +HEAT repeat [IPR000357] 0.6271669880689985 1.5976807316707844 0.1101140491063978 0.999874470736824 0.2125919084043802 7 Q8TEX9,Q8TF05,Q6PJG6,O00410 4 +HEAT repeat associated with sister chromatid cohesion protein [IPR026003] 0.6037003879438938 1.59099608814214 0.1116104561351396 0.9998897281263152 0.2125919084043802 2 Q6KC79 1 +Leucine rich repeat 4 [IPR025875] 0.5397123962591204 1.2362309718283824 0.2163727212155257 0.9999999929784172 0.3203980679537593 3 Q13045 1 +Regulator of chromosome condensation, RCC1 [IPR000408] 0.5132501412413898 1.009984399307054 0.3125027644276357 0.999999999999705 0.4078425908631855 7 O75592,Q9UII4 2 +Pumilio RNA-binding repeat [IPR001313] 0.4693184410189628 0.8762472984315444 0.3808956085447872 1.0 0.4888160309658102 3 Q86U38 1 +Plectin repeat [IPR001101] 0.3646395833620863 0.3614737701601906 0.7177453096935467 1.0 0.8484683264992327 5 P58107,Q9UPN3 2 +Ankyrin repeat [IPR002110] 0.3542106177024488 0.1668803480895817 0.8674641962567606 1.0 0.968114823276117 21 O15084,Q00653,Q8IWZ3,Q13418,Q9ULT8,Q9P2R3,Q6W2J9,Q9H6S0,O75832 9 +WD40 repeat [IPR001680] 0.1785069347096122 0.0777702748218689 0.9380107920687552 1.0 1.0 102 P57081,O94967,P53621,Q9Y263,P50851,Q99570,Q5TAQ9,Q5JSH3,Q9Y2X0,Q96BP3,O76071,Q8WUA4,Q15334,P63151,Q6UXN9 15 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ce3b2162a17c926992007e350424ee7d395f4ba8 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "Opioid growth factor receptor repeat [IPR006770]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACBD6", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD28", "ANKRD46", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMC8", "ARMCX3", "ARPC1A", "ARVCF", "ASPH", "ATR", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC23", "CDC27", "CDC40", "CHAF1B", "CIAO1", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1A", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GNB1", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HERC5", "HTT", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "JUP", "KAT7", "KDELC1", "KDELC2", "KDM2A", "KIDINS220", "KLC1", "KLC2", "KLHDC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MKLN1", "MPDU1", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NFKB2", "NFKBIE", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NUP214", "NUP37", "NUP43", "NXF1", "OGFR", "OGT", "P4HA1", "P4HA2", "PAAF1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNA1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RBBP4", "RBBP5", "RBBP7", "RCC1", "RCC1L", "RCC2", "RNH1", "RPAP3", "RRP9", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SIN3B", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TLE4", "TMTC3", "TOMM34", "TOMM70", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR47", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", 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3.985647205406728e-05 95.53883495145632 459.4053398058253 -0.3679802646226137 0.674897329309356 40.589299209189946 27.178272851227945 0.797777846812604 0.352052830899136 0.0188824572326359 4.714370162821155e-05 1.2362696000389336e-06 7.673013806835936e-13 +Cell projection organization 83 261 4.010477812742406 6.05959947643786e-05 54.529126213592235 250.1771844660194 0.0885716979556682 0.8002003294890062 21.77302656141916 31.312086500340524 0.7390344422983982 0.3036099690788064 0.7175977951597 0.9260302863613346 0.7858635958806376 0.5543535827331132 +Mitotic cell cycle phase transition 53 135 3.7199120422752032 0.0001992921708013 33.199029126213595 123.11893203883496 -0.1930161734817196 0.6691272636801149 12.844824390411528 14.986172617891643 0.7938441614872981 0.3122704306923669 0.8201610143155756 0.1203784249055127 0.0115163008002395 4.012364041526125e-05 +Ncrna metabolic process 71 294 3.69163458681331 0.0002228174375509 113.01941747572816 270.2160194174757 -1.3816986520051675 0.3815927844735612 32.26753473259024 24.64681463259712 1.552344895354134 0.3423411863695943 0.0080043843240465 0.0022923045020488 2.226269484798657e-06 1.303493140574821e-10 +Regulation of cell cycle 106 301 3.65674364747596 0.0002554396096563 78.84708737864078 274.5728155339806 -0.5248527779594999 0.6006517722624302 28.05582881241594 31.316843677133416 0.7148762158675183 0.3127931671207949 0.0122528542852183 0.040066869508684 0.0031301121330114 0.0029859315097871 +Regulation of phosphorus metabolic process 88 261 3.6255083333526295 0.0002883935959081 49.237864077669904 230.86893203883497 -0.228209860302787 0.742071515463957 18.230368435714993 27.6459464509743 0.5607059177051656 0.284326761629585 0.3618522534465818 0.2657890857171022 0.3530447911438716 0.0432364298094693 +Mitotic cell cycle process 94 267 3.5648167290238955 0.0003641105213949 67.25 248.4490291262136 -0.3996043612471873 0.6643452131300858 22.717516551164373 25.80744274427731 0.6370041969167247 0.3067027905264513 0.3368100345549194 0.0676874076150184 0.0071965931315495 1.2359093244768496e-05 +Modification dependent macromolecule catabolic process 51 198 3.5343345751262936 0.0004088032437976 46.601941747572816 189.19174757281553 -0.1203627158490638 0.7444313153045039 17.9667112927274 21.40546227934803 0.7498644427259226 0.3005465268627684 0.2559360757898127 0.0328058305244536 0.0374248492539032 0.0014981277724479 +Ncrna processing 57 230 3.397306723447322 0.0006805264201021 90.49514563106796 209.4368932038835 -1.4190091451530638 0.379336465165335 26.280368023020408 19.015282511406305 1.550113673016317 0.3570702883491011 0.0083141684637973 0.0029229905331387 3.535972330194216e-05 1.28517045871472e-09 +Positive regulation of phosphorus metabolic process 57 151 3.3696503353618 0.0007526362318339 28.983009708737864 132.4757281553398 -0.1631980798460764 0.7270941344425156 12.500570964431942 15.79301471506242 0.6133249729237237 0.2818526922362523 0.4157147458267625 0.3247961018067472 0.4027223077574861 0.1074101142926037 +Regulation of mitotic cell cycle 51 147 3.3525301881716905 0.0008007650807357 34.21601941747573 130.87864077669903 -0.2872439746549409 0.6797808159475265 13.939516911563985 15.822431848765309 0.6622259724500822 0.3013631963908394 0.2518043791564978 0.2683461185991564 0.0031972992182294 0.0003806060657645 +Cell cycle process 150 377 3.289331367540477 0.0010042571445267 89.50485436893204 352.1383495145631 -0.4092680147843046 0.6573590167620477 30.54000203025399 36.72004803064649 0.7365506626928265 0.331104993892801 0.2785308588538249 0.1016845022790358 0.0387244620585354 3.096656471615248e-05 +Cellular protein catabolic process 70 243 3.1504140648910357 0.0016303921255409 52.41990291262136 236.80339805825244 0.1673159010482066 0.8063536769071427 19.666167587086957 24.460046442072542 0.8282412046097252 0.3133286292668994 0.0896056753241077 0.0215618979871409 0.0266421249798225 0.0040180107356382 +Regulation of protein phosphorylation 69 197 3.1327275175238603 0.001731901415644 38.89563106796116 172.45873786407768 -0.242865134793112 0.7191295653170918 15.121555383726651 21.723119677065267 0.584179155703641 0.2897617850444039 0.185229627763937 0.2614221895765573 0.2768177792129555 0.0159484804224081 +Regulation of protein modification process 101 337 3.0334686412252645 0.0024175983616281 70.08252427184466 306.1626213592233 -0.3068380603352445 0.6972889395122394 26.35590951653131 35.68878778707677 0.6720214352667823 0.3181738913394558 0.1897170716840714 0.4759201554554796 0.2154416152335339 0.0096420157658769 +Peptidyl amino acid modification 80 275 2.963787125159543 0.0030387842196759 54.54368932038835 254.5898058252427 -0.2304220871421795 0.7328759062494112 20.941910734788895 33.76013609692183 0.6112933811980946 0.2982495414947489 0.4178257586320668 0.8602337058928758 0.7414634694933036 0.0445135229183071 +Cellular response to dna damage stimulus 61 257 2.914437656661098 0.0035632997166226 65.79368932038835 244.25 -0.6031158619367845 0.560930854707227 26.456387614567035 27.184878095871216 0.7030285034505063 0.3143026928513596 0.1045122836310018 0.3267403168551932 0.0020778179080398 0.0006866336224588 +Trna metabolic process 39 98 2.9066976271990588 0.0036526608708278 33.398058252427184 85.2378640776699 -0.8476123546419412 0.4662477853848542 11.309279466652995 11.109635601801982 1.0624472864677814 0.3511334954540809 0.2124021777965604 0.2471395654652882 0.0014065760776455 0.0027935862087372 +Regulation of cellular component biogenesis 72 233 2.8881789063680485 0.0038747941361323 53.88106796116505 220.94417475728156 -0.3327641715205899 0.701895570871007 20.664517002270554 21.86430548670737 0.6160018421803148 0.3012637698106144 0.2445020777806348 0.3590717165069996 0.2578571221548475 0.0672241731444628 +Dna repair 34 187 2.8872212586256625 0.0038866081099639 51.06553398058252 176.0121359223301 -0.7749883955607816 0.4953072089365344 21.431264623340393 19.564490031562727 0.902499791044042 0.3370329645771007 0.1834804969586854 0.2891991878523292 0.000402495932592 0.0006186167793557 +Cell division 76 220 2.830664111077023 0.0046451474165889 51.96601941747573 198.19417475728156 -0.3739262501223273 0.6620631032691738 17.48338491919207 21.25575113605279 0.6010480882580446 0.2971087980805138 0.0324060270309886 0.2089837784674712 0.0649553881582693 5.295908436746557e-05 +Protein catabolic process 103 282 2.762595504130409 0.0057343782771006 57.939320388349515 272.5995145631068 0.2544869136537276 0.7930564725881051 20.71908054348103 28.634409671583583 0.857305499882716 0.324900240064613 0.1511314327464146 0.0570477947914803 0.0444203028833284 0.0065172168233224 +Cell cycle phase transition 60 162 2.7364420806098173 0.006210752712711 41.56553398058252 152.08252427184465 -0.308610635417948 0.6664457289791409 15.430491704071772 17.525791962684988 0.715250826938827 0.3072179719762865 0.610594265708642 0.1131980822164677 0.029711322364353 0.0001970415072805 +Negative regulation of cellular macromolecule biosynthetic process 27 107 2.7291650480245315 0.0063494916065178 25.16504854368932 104.32766990291262 -0.014783617666872 0.7308642362337194 10.768839520082652 9.158099572210986 0.6801694709390934 0.2968811022295142 0.020644202656632 0.1595902374508502 0.0180801398202815 0.0050922105438928 +Positive regulation of protein phosphorylation 42 117 2.713868678018636 0.0066502523004894 23.52912621359223 102.41747572815534 -0.1488034303965219 0.6803237542322728 10.19954435559452 13.30415240810006 0.7080058848245556 0.295006179138482 0.2858811680905303 0.5155915812489715 0.6060978265738644 0.136135777362907 +Rna decapping 4 6 2.696842113020103 0.0070000451483356 2.4199029126213594 6.279126213592233 -0.0848810557566545 0.4946047197410289 1.6312756311392622 1.6346524269353602 0.9873567578795914 0.2905803749724461 0.0742352733278267 0.1432798584585485 0.0565188023636715 0.0007525839576665 +Methylguanosine cap decapping 3 5 2.662256723322304 0.0077618654343418 2.29126213592233 5.912621359223301 -0.0776582949465311 0.502460193343784 1.5336425828925908 1.3924679223894492 0.9464442183064392 0.2839663247492288 1.0 1.0 0.2740704871267072 0.0028040242445346 +Dna metabolic process 47 306 2.589354751227209 0.0096155978473182 81.51941747572816 290.90776699029124 -0.7606019924281333 0.5126901611453574 31.197649146722977 29.100616179111377 0.8842055913364671 0.3297418041264707 0.0223887443305945 0.1654911305885218 0.0008664129272058 0.0013755957542536 +Methylation 44 113 2.547645082983536 0.0108452746143594 29.597087378640776 106.00970873786407 -0.5337307051651653 0.5231405637645905 13.05413639248227 14.563216828063291 0.9501349253810486 0.3330534651638011 0.7704993360143175 0.1634987855413628 0.0324035972045496 0.0120593332615794 +Positive regulation of amyloid beta formation 1 5 2.544565863601957 0.0109413675371556 1.587378640776699 3.4927184466019416 -0.2421971958287762 0.5138796926065503 1.1489277070593424 1.2761613360696755 1.0915238255417603 0.3255789334287305 0.0561990347849709 0.1094892401774078 0.0331187861076589 0.113339965404402 +Ribosome biogenesis 48 213 2.519526137668001 0.0117512915323987 87.91504854368932 201.40291262135923 -1.367945807649791 0.3907715011291417 26.09430371101502 12.534333092739464 1.6375775879434369 0.3673658004627615 0.0130333326302935 0.0020297109911338 0.0008353354735575 7.048791025876209e-11 +Microtubule based process 75 231 2.5110758522064707 0.0120363831091419 53.70631067961165 215.72815533980585 -0.2687105731307709 0.710983757664987 18.718498689398988 25.10490385498623 0.6654715310458168 0.3065400983541795 0.5984716168712049 0.7411012731524536 0.2880278766117587 0.0073374496636051 +V d j recombination 4 8 2.5089812020166327 0.0121079927602898 2.9563106796116503 6.478155339805825 -0.2388966821444213 0.4835040509480232 1.730097359789895 1.245188212523476 0.9853013900358896 0.3049031121528418 1.0 1.0 0.0840389641709933 0.0022722304352638 +Macromolecule catabolic process 104 430 2.5089244329454807 0.0121099387645702 84.74271844660194 417.9004854368932 0.1286547603598417 0.8124763628759076 28.861517705424525 39.41436951209794 0.7619187608747271 0.3155632238758567 0.0537159495268932 0.0657190044912195 0.0009781116369886 2.312696798033788e-05 +Negative regulation of histone h3 k9 methylation 0 5 2.485932101514555 0.0129212616019711 2.2742718446601944 4.854368932038835 -0.5119783484231395 0.4691448713329584 1.3492242301366586 1.0785442093219757 0.9551021963698382 0.3055421953942681 0.0516364610584135 0.1008375048293403 0.2373820829012167 0.4230365159515766 +Phosphatidylinositol 3 phosphate biosynthetic process 3 5 2.4819525304135865 0.0130664680738052 1.711111111111111 3.659259259259259 -0.013954662084488 0.5428870750366666 1.218377792166471 1.3061845083378052 1.0294298241292634 0.3202812973428339 1.0 0.1677870330809631 0.0768284795296569 0.0624183143373935 +Regulation of cell adhesion 37 106 2.478794383871193 0.0131827276180764 23.776699029126213 96.51699029126212 -0.176984172235512 0.6866740613717985 8.820686232286333 12.118036091241995 0.6743187700072281 0.2984278173813429 0.547205515306446 0.7098246938456004 0.2104174426922722 0.2225298154238334 +Positive regulation of cell death 44 122 2.4536748752580304 0.0141404765747639 22.145631067961165 115.04854368932038 0.0919534668039154 0.7739555792829144 8.324612900403181 10.941484822096536 0.5689764092527864 0.28244576966447 0.5053785480519754 0.6592170702836114 0.0854242889404926 0.0035923071989005 +Histone h3 k4 demethylation 2 5 2.437267481316411 0.0147987281750685 0.9902912621359224 3.366504854368932 0.4934433344412655 0.4871635525973559 1.1212436371311745 1.0353670225266298 1.00941667866664 0.3191674234627318 1.0 1.0 0.1788587842302525 0.0546176715347421 +Regulation of fatty acid transport 2 5 2.4226140231394573 0.0154092891326098 1.3810679611650485 4.548543689320389 0.6157357570119139 0.4735209512695758 1.030096057940794 0.7883082633044994 0.8644473952298549 0.3082995501275736 1.0 1.0 1.0 0.010684483318579 +B cell homeostasis 2 5 2.4115183327738814 0.0158862531671215 1.4757281553398058 4.536407766990291 0.4480782451254183 0.4467870426707374 1.122104993046938 1.5204542974451043 1.0822082623347038 0.3160935496142801 1.0 1.0 0.4185863086244521 0.0892170338783466 +Dna dealkylation 4 8 2.4063613130008914 0.016112320426469 3.7305825242718447 7.439320388349515 -0.3455100653685099 0.4809796209240795 1.9676353780753744 1.0328147627936528 0.9439003459529144 0.2997425564658039 0.1006582454154426 0.191600110602388 0.0990342687178565 0.0035606647558243 +Neuron projection arborization 3 5 2.399812683228076 0.0164034634775203 2.1189320388349513 6.410194174757281 0.2997181931700579 0.5356389026564765 1.6063982583137093 1.2538070031432729 0.9306716986687408 0.3086593014216465 1.0 1.0 0.3258327648280404 0.1818418904091173 +Embryo development 56 213 2.3873833552867487 0.0169687866001875 42.95388349514563 194.7864077669903 -0.2656910139874744 0.7329234540054056 16.960986343193586 21.76357984073878 0.5374386882600177 0.2834231769355864 0.4487886254833455 0.3753941546239783 0.1446880206186231 0.1102548172005607 +Replicative senescence 3 5 2.3783561950153405 0.0173900184811954 1.422330097087379 3.1262135922330097 -0.1510575384453819 0.5671632777154402 1.1153328589177065 1.425697660254806 0.9915353344519882 0.3162937917203501 0.0652597674910206 0.1265462710440741 0.0002821754852333 0.0037759888499611 +Cd4 positive alpha beta t cell differentiation 3 5 2.375106789689572 0.0175438736474637 1.83252427184466 4.847087378640777 0.0335821750686967 0.5344101005518149 1.232099178367232 1.037367964290322 0.9445035588204572 0.311696213468694 1.0 1.0 0.534424974066877 0.1905468417868487 +T cell differentiation involved in immune response 3 5 2.375106789689572 0.0175438736474637 1.6310679611650485 4.381067961165049 0.0779130978869904 0.5404950204177928 1.1426446182154013 0.735989410832118 0.9413992671049548 0.3109028421032308 1.0 1.0 0.510851629797044 0.1659016353191164 +Tetrahydrofolate biosynthetic process 0 5 2.36879290659137 0.0178462430462738 1.7936893203883495 4.983009708737864 0.1605580267226933 0.4510199931505445 1.7386689978430927 0.1292347525434382 1.0823232133771 0.2967084841927126 0.028497516818446 0.0563150378970086 0.1373795195898598 0.0312108672695238 +Telomerase holoenzyme complex assembly 2 6 2.338334482150383 0.0193699035797654 2.058252427184466 3.968446601941748 0.0224808975890244 0.5606646766678688 1.22335875961515 0.9661627205023248 0.9167055058799828 0.3138715630914188 0.0378187125466048 0.0743799864466655 0.014977467250991 0.0053637976870067 +Regulation of cellular amide metabolic process 51 196 2.33106223187823 0.0197500784368047 41.689320388349515 188.22815533980585 -0.1411734936770823 0.7597737763252017 17.18123221177186 13.079717623178382 0.6060848017020994 0.2981203052557788 0.0996296093114307 0.063674526033389 0.0038023770774925 0.0010409354600547 +Positive regulation of calcium ion transport into cytosol 1 6 2.316840672370383 0.0205124125467754 2.4150485436893203 6.754854368932039 -0.1252435055298218 0.4951723805807685 1.6175814223208935 0.9682336676145236 0.993285888866281 0.3039119708047215 0.083126337411673 0.1596960736798767 0.0698282842903305 0.2179847922025966 +Positive regulation of release of sequestered calcium ion into cytosol 1 6 2.316840672370383 0.0205124125467754 2.2985436893203883 6.393203883495145 -0.0768098245406624 0.505909583507104 1.550351609206413 0.9832344223557812 0.9755496629465316 0.3017713651491867 0.0697581245313758 0.1349531130589082 0.050241067872642 0.1641299211995837 +Regulation of cytoskeleton organization 51 141 2.3071674847578088 0.0210454849909096 40.179611650485434 135.42233009708738 -0.4417351969096031 0.5790301794162391 15.770402776488616 15.738959342109927 1.0277026860444949 0.3450236295087346 0.574203789041838 0.533832524549624 0.5010838988944584 0.076253905491917 +Ribonucleoprotein complex biogenesis 57 293 2.297611625465212 0.0215839033965759 113.1626213592233 278.9101941747573 -1.242536057473473 0.4052832757395683 32.8107290782 16.65072939191207 1.4969429112355046 0.3439112060869881 0.0006650645098113 0.0005277592682619 2.024471025372493e-05 4.139867530921686e-12 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 2 6 2.295659896365207 0.0216953351574282 1.7378640776699028 5.475728155339806 0.2504530407094367 0.5306514139754194 1.3596913202559946 0.9040863026311896 0.8846503173967747 0.2971649214887787 1.0 1.0 1.0 0.1641299211995837 +Peptidyl methionine modification 2 5 2.294126081368524 0.0217832576379557 1.4174757281553398 3.7257281553398056 0.0489910144075628 0.4851192561449486 1.0122959757969805 1.0905677704860026 1.136074364357859 0.3094182208982063 1.0 1.0 0.0280420066437826 0.0141665154869097 +Retrograde axonal transport 3 9 2.289367056377902 0.0220580345623178 3.0898058252427183 8.951456310679612 -0.160267704010341 0.5433978483006399 1.8938308023493629 1.5352090447877251 0.9081817538614372 0.3039851939919125 1.0 0.1596960736798767 0.0007989256016515 0.0098879726868235 +Rna guanine n7 methylation 2 5 2.278766742983898 0.0226809348379481 1.538265306122449 2.836734693877551 -0.4115788663612535 0.4645976300760012 1.13099425783039 1.244939778487956 1.1823973779815755 0.3307496872673428 1.0 1.0 0.1373795195898598 0.002061539822863 +Negative regulation of cell aging 2 6 2.278656037105954 0.0226875200253007 1.4150485436893203 4.436893203883495 0.4449080488727195 0.4593397992109042 1.033453418648996 1.1399191157868775 0.9851582751260632 0.2986294132747129 0.0786913117950012 0.0113213926532688 0.0630532374058985 0.0470360579614364 +Regulation of organelle organization 108 352 2.2772072549371685 0.0227738521109213 75.80339805825243 332.36893203883494 -0.3146431889050748 0.7297269830137101 26.476545548491696 34.64416629221664 0.5756395609674254 0.3073335058256338 0.2642607760662784 0.3680544129255587 0.0486744587576497 0.0021323375572585 +Heart valve morphogenesis 3 5 2.260928525083821 0.0237636834132342 2.174757281553398 4.817961165048544 0.1161495230118911 0.557475135117042 1.510013080802465 1.5698518013186775 0.927222008360361 0.3089359109336025 0.134742527043449 0.2518545844225215 0.5227832512917782 0.4336067804253886 +Base excision repair gap filling 3 8 2.258995214982245 0.0238836825262716 4.691747572815534 9.300970873786408 -0.6287292395647202 0.4057853647795099 2.326426872810092 1.3225817019658803 1.0169666536153072 0.3179099055464128 1.0 0.1432798584585485 0.0062969264366488 0.0063533232968262 +Regulation of cell cycle process 73 202 2.2468940132269664 0.0246468014206029 53.76699029126213 190.4490291262136 -0.4831179666706685 0.6204573250640321 19.056611565011018 22.190149656454565 0.64891444197436 0.2993590444411109 0.2327618278155111 0.3731664819607898 0.025596791378506 0.0038423381134884 +Negative regulation of signal transduction by p53 class mediator 2 6 2.2428533751370217 0.0249062712276759 2.1262135922330097 6.490291262135922 0.0025135391117914 0.5277846023571443 1.4626721898500985 1.409882909350627 0.9389842991964372 0.2948801347666068 1.0 1.0 1.0 0.7137322392843504 +Regulation of mitotic cell cycle phase transition 37 100 2.241561253564787 0.0249897425296075 23.533980582524272 89.59708737864078 -0.1477831816283192 0.7055773066600903 9.931381599034568 11.86157176433715 0.6604983630963074 0.2873081594869724 0.7031108627898817 0.4302767274820046 0.0078392962099841 0.0023981559256281 +Positive regulation of cyclin dependent protein kinase activity 3 5 2.23956004626328 0.0251194989798138 1.796116504854369 4.233009708737864 0.0855480564943321 0.5916736050179213 1.3282532752173617 1.1100064155779403 0.8594485194190593 0.3035014869334123 0.1221118561195742 0.2297987482657219 0.1392702662277763 0.3817623273994432 +Microtubule cytoskeleton organization 60 178 2.23347771922696 0.025517458024727 43.83009708737864 164.70631067961165 -0.2059463215733804 0.6768554367174028 16.009713889558597 20.221195718646996 0.7870016820046382 0.3160833319212116 0.3973626214286082 0.4777016244383445 0.2593962366289483 0.0049621030661502 +Cell projection assembly 38 102 2.231379097582327 0.0256560282345892 25.51456310679612 100.21116504854368 -0.0847517188572289 0.6894687163325205 10.924155187322135 12.83697525097397 0.7831001177176707 0.3205242460177137 0.5933641967694233 0.9103150852237056 0.7883513004794265 0.9067613010587336 +In utero embryonic development 32 107 2.230855216301352 0.0256907210252861 19.398058252427184 91.57766990291262 -0.0496829457479905 0.7374375830880433 9.612986569881556 10.212370492471468 0.6071598886208166 0.2814121516332231 0.7478227670853946 0.5121905045774231 0.1499701191537747 0.0055684832457837 +Ribosome associated ubiquitin dependent protein catabolic process 3 5 2.224290761477929 0.0261288878828782 2.2645631067961167 4.674757281553398 -0.376980216600952 0.4712432960287969 1.391864905772268 1.2583868890158458 0.9888527265101272 0.308956143462896 1.0 0.0563150378970086 0.1373795195898598 0.002061539822863 +Positive regulation of cellular component biogenesis 38 120 2.222857765958578 0.026225392420841 30.02912621359223 113.6868932038835 -0.2821691302797726 0.639072582262895 12.858419711960115 11.897275655280112 0.739470936212581 0.3059892639937149 0.0818012239267977 0.2339351703931626 0.214206394124628 0.0749090049708588 +Interleukin 1 mediated signaling pathway 0 5 2.1901882745078702 0.0285105852649796 1.8155339805825244 4.182038834951456 -0.319987471901798 0.5221382914764632 1.3723877060931475 1.7104384603507918 0.9732987627250466 0.3151189282152458 0.083126337411673 0.1596960736798767 0.3582816735878424 0.5935435236326052 +Meiotic chromosome condensation 4 6 2.1829553199646585 0.0290391005145731 2.495145631067961 4.800970873786408 -0.1376716624019681 0.5326480852952579 1.3301856678037194 0.7368254058888809 0.8794430593042172 0.285861970449791 0.028497516818446 0.0563150378970086 0.0082857576662697 0.002061539822863 +Positive regulation of chromosome condensation 3 5 2.181657385342147 0.0291348282364378 3.0825242718446604 5.0 -0.2226465403007374 0.5218593115505167 1.3321948591008603 0.0 0.8807437141268603 0.2943938161041132 1.0 1.0 0.0056136137273067 0.0010694525645264 +Glucosamine containing compound metabolic process 2 5 2.18048823352399 0.0292212900957995 1.0631067961165048 4.043689320388349 0.3888966696826618 0.521842041001074 1.1970424955561958 1.0465078221995192 0.9423128491171514 0.3121597137993275 1.0 1.0 1.0 1.0 +Protein localization to early endosome 0 5 2.1667341877859574 0.0302551281816447 2.7888349514563107 5.531553398058253 -0.0706540976486223 0.4831219123356118 1.5785490455680595 0.9407054337932064 0.9892623596885428 0.295398516196228 0.0424464003246627 0.0832836732680532 0.1988473022417859 0.3623306062719575 +Positive regulation of amyloid precursor protein catabolic process 2 7 2.1626893331626 0.0305650820721563 2.279126213592233 5.871359223300971 -0.0450573145953618 0.571952895661042 1.647961734165576 1.4616306551004925 0.8563671318045422 0.3064621950738684 0.0786913117950012 0.1515272625734178 0.0630532374058985 0.0470360579614364 +Histone mrna catabolic process 2 9 2.156637954512644 0.0310338848257369 3.342233009708738 6.441747572815534 -0.6936818910624533 0.4572726158552449 1.738167449249009 1.7063572892030667 0.7497811460769238 0.2932336276177549 1.0 1.0 0.005208827916976 0.0338099842169397 +Protein localization to cytoplasmic stress granule 1 5 2.153436438011671 0.031284394472077 2.2694174757281553 6.140776699029126 0.055341278032029 0.5648422458582549 1.7370146945305291 0.6716068101338981 0.8280966473335474 0.2895681893300761 0.0331691185540615 0.0653907127050202 0.1583736196074974 0.295251642909297 +Positive regulation of fibroblast proliferation 8 10 2.1510386416537304 0.0314731498186398 2.2184466019417477 6.686893203883495 0.3895883807436451 0.5595634829228668 1.7847382975769774 1.3764746931300986 0.7848609912150716 0.3030107819452191 1.0 0.2372212797486779 0.1476943407876319 0.010448798153629 +Regulation of endoplasmic reticulum tubular network organization 1 5 2.148839984830751 0.031647086575969 1.6067961165048543 4.33252427184466 0.2641476128934525 0.5002473707462866 1.134521167197805 1.051402409218234 0.9798163104482444 0.3147156315055147 1.0 1.0 0.0082857576662697 0.0312108672695238 +Neurogenesis 85 277 2.146692401530105 0.0318177780999451 50.133495145631066 264.67233009708735 0.0770609350888286 0.8305235878729872 18.870770134095213 30.203547522106778 0.5789729297783478 0.2710717183044796 0.9554636721825838 0.9169887714501928 0.9173215600675696 0.4940097856583851 +Regulation of transferase activity 61 185 2.14434807243601 0.0320050076619329 42.71116504854369 169.11650485436894 -0.3292650030896277 0.6752884902708919 17.41822980990385 19.421013027318065 0.6215859205437844 0.2885319592190213 0.2992387167817261 0.188686734358589 0.5410403802554992 0.0732871493211822 +Regulation of lipid kinase activity 3 5 2.1441545164617257 0.032020508104706 2.737864077669903 6.235436893203883 -0.1877079468009178 0.5777210673924097 1.9306478868707568 1.7223281131981438 0.8155787039768105 0.2965353724772596 1.0 1.0 1.0 1.0 +Trna 5 leader removal 2 7 2.1437458954862323 0.0320532526190016 2.4029126213592233 5.305825242718447 -0.4665723187648057 0.518910311439769 1.4457138734948416 1.2419312585700106 0.8405317066334042 0.3100390208516801 0.0017062060788896 0.0066572828402184 0.0033939033653995 0.0228394808772788 +N terminal protein amino acid modification 5 8 2.1368387304151355 0.0326111107815381 2.45873786407767 8.439320388349515 0.5804938412353885 0.4249038973587519 1.7696871423418874 1.4824892226959214 1.0345977331938565 0.310740936912418 1.0 1.0 0.1309570889500886 0.0075753503172145 +Negative regulation of cyclin dependent protein serine threonine kinase activity 5 7 2.130172333253079 0.0331573883067075 2.521844660194174 5.883495145631068 0.0909727643578148 0.5803620880436494 1.6493624820604984 1.765642823470682 0.8450320982652144 0.3034042488599743 1.0 0.2223047329091382 0.0244664942800011 0.0355737118947821 +Glycine metabolic process 0 8 2.1135609071314194 0.0345527877540106 1.9611650485436891 7.745145631067961 0.2494288083790708 0.5022368368742125 1.850858263769758 0.52194625337572 0.9488090090216508 0.2970164640348599 0.0424464003246627 0.0832836732680532 0.1988473022417859 0.3623306062719575 +Negative regulation of chemotaxis 2 5 2.111203297400294 0.0347548415411984 1.8033980582524272 5.155339805825243 -0.0632726487639227 0.4544165494926578 1.311890397237956 0.9952048289283428 1.0730906602614034 0.2945723505476881 1.0 1.0 1.0 0.09905667817091 +Dna replication 36 119 2.087452375677259 0.0368472617354878 31.58495145631068 114.497572815534 -0.3396652183206484 0.6367066368556744 13.744197954949136 11.241933199852268 0.7082885401335637 0.3115012314696074 0.0081773982636261 0.0402666203489318 0.0264400608234154 0.0312242143634485 +Regulation of notch signaling pathway 2 5 2.0853936940151088 0.0370335787843574 1.949029126213592 6.405339805825243 0.2153684160684993 0.5317261904436601 1.4877571668458458 1.96653325419933 0.9076755012121464 0.3035366773928155 1.0 0.4353012614103685 0.7670690940683371 0.7899498271827039 +Establishment of organelle localization 35 140 2.082349457188027 0.0373105614938038 31.79368932038835 135.27184466019418 -0.2340291108394643 0.7643646045107365 10.36698732490497 13.460077016728318 0.5051667872105723 0.2697523961859881 0.7901335193339849 0.3678300586898117 0.0049114991869312 3.3941693011960994e-05 +Embryo development ending in birth or egg hatching 42 146 2.0820731059703887 0.03733579264354 29.446601941747577 129.0364077669903 -0.2477273238448529 0.7087741729233749 12.884082265797629 14.827360392938306 0.5749964171833254 0.2866852923144399 0.6530973398342006 0.6477066958991271 0.2254630490779766 0.015521546663972 +Regulation of synaptic vesicle recycling 3 5 2.081564891302099 0.0373822310780069 2.3106796116504853 6.16747572815534 0.1594000361571566 0.5501436327851555 1.5042278683349732 1.122847644133054 0.8790206616335426 0.2998156001661948 1.0 1.0 0.3582816735878424 0.5935435236326052 +Regulation of clathrin dependent endocytosis 3 5 2.078350132645286 0.0376771221438587 1.2815533980582523 4.002427184466019 0.2305754466030533 0.5589467205387074 1.1837694912075136 1.420205759753742 0.9091382205378896 0.3085600932066642 1.0 1.0 1.0 0.5935435236326052 +Negative regulation of biosynthetic process 72 339 2.070449399257536 0.0384102799098324 80.95388349514563 311.25970873786406 -0.5476228975724882 0.5887399760511899 26.8787335987007 33.504499450227755 0.7457592290547543 0.3263433128114437 0.4245138561796939 0.6060830288518824 0.4825297977720031 0.4595719035898188 +Neurotrophin trk receptor signaling pathway 5 6 2.063535717828896 0.0390617578848671 2.313106796116505 5.66747572815534 -0.1413624702694373 0.4615946426465154 1.411300804034482 1.2222096958676991 1.0502739438284965 0.3035060076734568 1.0 1.0 0.0630532374058985 0.0079931710216612 +Regulation of protein containing complex assembly 38 113 2.054380997537058 0.0399388307766785 25.788834951456312 105.27912621359224 -0.2293438953534996 0.6729629735276286 12.991280556100776 8.479973622279468 0.755717464199114 0.3176815373669173 0.7612057723597634 0.777573398743055 0.4206029659494701 0.0290484093484997 +5s class rrna transcription by rna polymerase iii 1 5 2.052418928845269 0.0401289664922184 2.3300970873786406 4.558252427184466 -0.2936795701220037 0.5513215717110854 1.2970343283145855 0.7432576252185813 0.8344273461054379 0.3024483994651719 1.0 1.0 0.1373795195898598 0.2591162943571684 +Chromosome organization 71 376 2.0520341549991787 0.040166343192622 101.62135922330096 353.40776699029124 -0.718702440590963 0.5246431988621554 35.54447958854473 36.06801473947072 1.0234435411635794 0.3402503944183533 0.0055933220128913 0.1034193692332719 0.0036613191460466 0.000286445712595 +Histone h3 deacetylation 1 6 2.0281432929398653 0.0425456254902663 1.9733009708737863 5.135922330097087 0.0810244323193268 0.5973122067338784 1.3022630700404934 0.9035909342681888 0.837571976038985 0.2998665173144875 1.0 0.1180585699575878 0.0385233102424958 0.1297945989547683 +Regulation of peptidyl threonine phosphorylation 4 8 2.0213578452184557 0.0432427351415247 2.563106796116505 8.009708737864077 0.03818910591028 0.5293686155535875 1.8704129802666387 1.424440926820526 0.934047724902416 0.3020531226500109 1.0 1.0 0.1309570889500886 0.0355737118947821 +Mrna methylation 4 8 2.021006450675089 0.0432790973378693 2.825242718446602 6.956310679611651 -0.3198930569803861 0.5716903209342071 1.9178628096456056 1.5682016107081682 0.7511489310167893 0.2882216460814402 1.0 0.1432798584585485 2.867880480409346e-05 0.0007525839576665 +Vesicle transport along microtubule 5 12 2.0202425457707536 0.0433582351153014 4.514563106796117 11.58980582524272 -0.102125747194735 0.5711972684164484 2.4921783572738394 1.5404554115317726 0.8762002857901487 0.2964402233799867 0.1715759324473242 0.3143397790261298 0.0023954143814766 0.010788368915323 +Regulation of mitotic cell cycle spindle assembly checkpoint 1 6 2.01982224155604 0.0434018292233244 2.138349514563106 5.012135922330097 -0.0651113965727923 0.5517262358220336 1.3909503610718048 1.276124404628415 0.9117858102355162 0.3052155168452798 1.0 1.0 0.3090006421698555 0.1641299211995837 +Posttranscriptional regulation of gene expression 56 234 2.013507175394817 0.044061300871881 53.11407766990291 221.8859223300971 -0.1598039017466293 0.741062027893887 18.793179300665894 15.710490462015317 0.6259460047817468 0.3081327162064205 0.0157026525316261 0.0210839408655376 0.0002817824293098 4.816100103965518e-05 +Regulation of microtubule depolymerization 8 10 2.010604644012079 0.0443672331460955 4.616504854368932 10.283980582524272 -0.327097129738729 0.5243890272187798 2.7383503320865596 2.0466490916806745 0.9334996438116826 0.3185301159472928 1.0 0.2297987482657219 0.1392702662277763 0.0016034677277021 +Positive regulation of lymphocyte differentiation 5 11 1.992297400126804 0.0463384367981061 3.145631067961165 9.684466019417476 -0.2392915071178997 0.5232598002814166 2.14931809908948 1.2627798954605274 0.9021091225516048 0.2930856392494232 1.0 1.0 0.0200675030127402 0.0171255123594616 +Fatty acid homeostasis 1 6 1.9868370222234213 0.0469404604648895 1.395631067961165 4.216019417475728 0.224786818794692 0.5081931774699484 1.1808670254733662 1.125363233533934 1.0069300689694072 0.308872933651965 1.0 1.0 0.2183511668733661 0.0823369674942117 +Regulation of cellular macromolecule biosynthetic process 65 270 1.9835108955815608 0.0473103912477581 61.12621359223301 264.02669902912623 -0.2558229644047513 0.7433416732970711 24.336009362311927 20.49737766265087 0.5506971948063403 0.2983529251303576 0.0522436837896902 0.0927794186292096 0.0195803211084286 0.0108077304859666 +Dna ligation 3 8 1.9793399852596665 0.0477777405618233 2.953883495145631 7.58252427184466 -0.3993195857514272 0.5156052642060028 1.9005133353604573 1.3092224910091774 0.8221706523845085 0.294676716689509 1.0 1.0 0.3422564852890665 0.0079931710216612 +Regulation of long term neuronal synaptic plasticity 1 5 1.9773088490484831 0.0480067300327169 1.4029126213592231 4.347087378640777 0.0838018245749516 0.516834669462952 1.1917154406124388 0.949407716306566 0.9753274202696696 0.3131238431631239 1.0 1.0 1.0 0.1641299211995837 +Snrna modification 2 5 1.9745679661018936 0.0483171973544913 2.5825242718446604 4.402912621359223 -0.6413105241592286 0.464620401603972 1.290550208881424 1.0347323945287994 0.8102615043982251 0.297496930225848 1.0 0.0563150378970086 0.0082857576662697 0.002061539822863 +Folic acid containing compound biosynthetic process 0 6 1.9742334196028493 0.0483552075905495 2.0364077669902914 5.548543689320389 0.1185786473734218 0.460967837187085 1.9007241105446349 0.5306826667147115 1.0747056928647158 0.3004314837246528 0.0378187125466048 0.0743799864466655 0.1788587842302525 0.0546176715347421 +Positive regulation of protein modification process 64 200 1.963921975377386 0.0495391409766594 42.41019417475728 181.3228155339806 -0.2897314660363225 0.7041059334454784 17.298751090257486 20.831155807274428 0.5805526999138245 0.2898177226402043 0.3168591237837281 0.6799877616467762 0.4735149336306836 0.0983796586853024 +Lymphocyte activation 28 105 1.962356920232274 0.049720944585418 19.75242718446602 96.97815533980582 0.2587104991344978 0.7054244518764566 7.147670469313885 9.69771309720366 0.6795078753957892 0.3167596875043957 1.0 0.6761325305099404 0.3761775242983325 0.0457040449031612 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ee916c811b43ef04d0255676ef0f6a3b99ca356f --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 6530, + "title": "Average number of proteins per term", + "value": 19.996324655436446 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9af319369ac5800f3944a25ba51fa79a5f921049 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e30c1a8fe186cf7380bccdf33d98d9dd1d33ebf6 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2271 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytoplasmic translation 0.6317327112650576 7.199966385560985 6.022740548759362e-13 3.932856100607369e-09 3.932856108339863e-09 115 P18621,P08708,P67809,P62847,P46782,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q9H2P9,Q02543,Q9ULC4,Q9UET6,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,O60524,P61247,P42345,P84098,P62854,P36578,P60866,P62851,P61313,Q7Z478,Q9Y295,P62906,P62753,Q14240,P50914,P62910,P41214,Q06787,P26373,Q04637,P62266,P62277,P18124,P61513,P39023,P61254,P62899,Q9BQC3,Q14152,Q9Y3U8 62 +Peptide biosynthetic process 0.3979752732670161 6.851754939981165 7.294944875129323e-12 4.763599543017417e-08 2.3817998282297246e-08 347 P00374,P41567,Q8WUX2,P67809,P62847,P46782,O75116,P46776,P62424,P38935,Q9H2P9,Q9ULC4,Q9UET6,P42766,P32969,P40763,P46777,O94822,P62917,Q96P11,Q92499,Q9BTE6,P84098,P62854,P61313,Q7Z478,Q9Y295,P62753,Q92616,P50914,P62910,P26641,Q8NE71,P47897,Q05639,Q06787,Q13464,Q04637,P62277,P39023,P62899,Q9BQC3,Q14152,P49207,P04818,P18621,P21399,P08708,Q8IZH2,Q86W50,Q92905,O43776,Q9P2J5,Q9UPY5,Q92600,O00178,O15371,Q5TAX3,P13639,P61927,Q9Y2L1,P49770,Q9BY44,P46778,P27635,P26640,P78527,Q9HCE1,Q86TB9,P36578,P62266,O60841,Q9Y3U8,Q96C86,A5YKK6,P62701,P15880,P62081,P62269,P62841,P83731,Q02878,Q8N3C0,P62280,P47914,P62750,P61247,Q14240,P26373,P61513,Q6PKG0,Q9UIV1,Q07020,P61353,P31751,P40429,Q13144,P62241,Q02543,P07814,P26196,P41252,P46779,O60524,P26639,P42345,P60866,P62851,P62906,Q9HD33,P41214,P18124,P61254,P63241,P82675 115 +Cellular macromolecule biosynthetic process 0.3340200142136157 6.491656804603073 8.489748391275573e-11 5.543804228349443e-07 1.3859514412007372e-07 570 P00374,P41567,P67809,P62847,P46782,O75116,O60701,P46776,P35244,P46063,P62424,P38935,Q13535,Q9UBD5,Q9H2P9,Q9ULC4,P78362,Q9UET6,P42766,P20248,P32969,P40763,P46777,P31949,Q08945,O94822,P62917,Q96P11,Q99873,Q92499,Q96QE3,Q07864,Q9BTE6,P84098,P62854,P61313,Q7Z478,Q9Y295,P62753,Q92616,P50914,P62910,P26641,Q8NE71,P47897,Q05639,Q06787,Q13464,Q04637,P62277,P60953,P39023,Q8WTT2,P62899,P35251,Q9BQC3,Q14152,Q7Z7L1,P49207,P04818,P18621,P21399,P08708,P49841,Q92547,Q8IZH2,Q86W50,Q9BY42,Q92905,O43776,P28340,Q9P2J5,Q9Y3Z3,Q92600,P33992,O00178,O15371,Q5TAX3,O95394,P13639,P61927,Q9Y2L1,P49770,Q9BY44,P46778,P35573,P27635,P26640,P78527,Q9HCE1,Q86TB9,P36578,Q13315,P49005,O43913,P62266,Q96JB2,Q9HC07,Q15042,O60841,Q7Z5K2,Q9Y3U8,Q96C86,P23921,A5YKK6,P62701,Q96HR8,P15880,P49427,P62081,P62269,P62841,P83731,Q02878,Q8N3C0,P62280,P47914,P62750,P17096,P61247,Q29RF7,Q14240,P26373,P28482,P61513,P61803,Q6PKG0,Q9BTE3,Q9UIV1,Q07020,P61353,O95352,P04183,P30419,P31751,P40429,Q13144,P62241,Q02543,P07814,P26196,P41252,P46779,P18858,Q06210,P49917,O43505,O60524,P26639,P42345,P60866,P62851,P62906,Q9BV10,Q9HD33,P41214,P18124,P61254,P63241,P82675,Q99805 161 +Amide biosynthetic process 0.3575182975133426 5.679985511230086 1.3470615236368225e-08 8.795924945083431e-05 1.2566159642859214e-05 385 P00374,P41567,Q8WUX2,P67809,P62847,P46782,O75116,P46776,P62424,P38935,Q9H2P9,Q9ULC4,Q9UET6,P53396,P42766,P08243,P20248,P22059,P32969,P40763,P46777,O94822,P62917,Q96P11,Q92499,Q9BTE6,P84098,P62854,P61313,Q7Z478,Q9Y295,P62753,Q92616,P50914,P62910,P26641,Q8NE71,P47897,Q05639,Q06787,Q13464,Q04637,P62277,P39023,P62899,Q9BQC3,Q14152,P49207,P04818,P18621,P21399,P08708,Q8IZH2,Q86W50,Q92905,O43776,Q9P2J5,Q9UPY5,Q92600,O00178,O15371,Q5TAX3,P13639,P61927,Q9Y2L1,P49770,Q9BY44,P46778,P27635,P26640,P78527,Q9HCE1,Q86TB9,P36578,O75592,P62266,O60841,Q9Y3U8,Q96C86,A5YKK6,P62701,P15880,P62081,P62269,P62841,P83731,Q02878,Q8N3C0,P62280,P47914,P62750,P61247,Q14240,P26373,P61513,Q6PKG0,Q9UIV1,Q07020,P61353,P31751,P40429,Q13144,P62241,Q02543,P07814,P26196,P41252,P46779,O60524,P26639,P42345,P60866,P62851,P62906,Q9HD33,P41214,P18124,P61254,P63241,P82675 120 +Phosphorylation 0.3584586511059515 5.598793674500335 2.1584850508511098e-08 0.000140939142494 1.761863422838843e-05 354 O75116,O75909,Q00535,Q13535,Q12923,Q9UII4,P78362,Q96JP5,P42858,P20248,P22059,P40763,Q9NYV4,Q00534,Q9Y3I1,O00443,P49407,Q9UJ70,Q08AM6,Q7KZI7,O14976,Q92616,O60271,Q9NR09,O75832,P47897,Q05639,Q06787,P35790,Q14147,Q13464,Q04637,P60953,Q92974,Q99996,P46940,P85037,Q9Y223,O95373,P11908,O75569,P36507,P49841,P68400,Q13523,Q8TF05,P42771,P42356,Q92990,Q969G6,Q92600,P17612,P15531,P12277,Q9BY44,P78527,Q9H2G2,Q9H8V3,P42574,Q15418,Q8TEW0,Q8IXJ6,Q15185,P19784,P14635,Q13315,P11802,Q9UDY8,P31689,Q96SB4,P33993,Q13418,O96017,P63167,Q6PJG6,Q8WVC6,Q96GX5,P49761,O00410,P46109,Q13526,P21359,P54132,Q8TBX8,Q9UNI6,Q5SY16,Q9HA64,P25440,P67870,P30307,O00764,Q96N67,Q13501,P17858,O15111,O60921,O95067,P28482,P49903,Q9H223,Q99986,Q7Z460,P53350,P08237,P04035,Q15334,Q99816,Q9UIV1,P04183,P31751,P49327,Q9UER7,Q9Y5V3,O14965,P14174,P51452,P27708,Q8WUA2,Q06124,P42345,Q16513,Q16512,P22392,Q13555,P22681,Q99570 126 +Peptide metabolic process 0.3521604699517469 5.561041039979946 2.681701191211361e-08 0.0001750997583882 1.9457231976959096e-05 393 P00374,P41567,Q8WUX2,P67809,P62847,P46782,O75116,P46776,P62424,P38935,Q9H2P9,Q9ULC4,Q9UET6,P42766,P32969,P40763,P46777,O94822,P62917,Q96P11,Q92499,Q9BTE6,P84098,P62854,P61313,Q7Z478,Q9Y295,P62753,Q92616,P50914,P62910,P26641,Q8NE71,P47897,Q05639,P27695,Q06787,Q13464,Q04637,P62277,P39023,P62899,Q9BQC3,Q14152,P49207,P04818,P18621,P21399,P08708,Q8IZH2,Q86W50,Q92905,O43776,Q9NQW7,Q9P2J5,Q9UPY5,Q92600,O00178,O15371,Q5TAX3,P13639,P61927,Q9Y2L1,P49770,Q9BY44,P46778,P27635,P26640,P78527,Q9HCE1,Q86TB9,P42574,P36578,O75592,P62266,P52888,O60841,Q9Y3U8,Q96C86,A5YKK6,P62701,P15880,P62081,P62269,P62841,P83731,Q02878,Q8N3C0,P62280,P47914,P62750,P61247,Q14240,P26373,P61513,Q6PKG0,Q9UIV1,Q07020,P61353,P31751,P40429,Q13144,P62241,Q02543,P07814,P26196,P41252,P46779,O60524,P26639,P42345,P60866,P62851,P62906,Q9HD33,P41214,P18124,P61254,P63241,P82675 120 +Protein modification by small protein conjugation or removal 0.3870933851599431 5.30760865982621 1.110727928575286e-07 0.0007250424072833 5.579271825893783e-05 235 Q70CQ2,Q9UPT9,Q2VPK5,Q96EP0,Q13616,Q9Y263,Q93008,O95352,O95071,Q00535,Q15369,Q9UII4,Q9Y314,Q9H1B7,Q15386,Q9NVI1,Q9Y4A5,Q9UER7,Q86VP6,P15880,Q96JP5,P49427,Q14999,Q86UV5,P62081,P62841,Q01804,Q13309,Q96BN8,P46777,Q5TAQ9,O94822,Q6GQQ9,Q9Y3I1,Q9NT62,Q5T4S7,Q7Z6Z7,P60866,P49407,Q96RU2,Q9ULT8,Q15020,Q9UDY8,Q13501,Q96FW1,P62942,Q9NR09,Q14258,O75925,O75592,P22681,P40818,Q9Y6J9,P29144,P52888,Q5T447,P53350,Q6W2J9,Q14527,O75155,Q99816 61 +Protein modification by small protein conjugation 0.3871917646351528 4.717436879763715 2.3883446405026376e-06 0.0154749227168942 0.0009174053236758 195 Q96EP0,Q9UPT9,Q2VPK5,Q13616,Q9Y263,Q93008,O95352,Q13526,Q92990,O95071,Q00535,Q15369,Q9UII4,Q9Y314,Q9H1B7,Q15386,Q9NVI1,Q9UER7,Q86VP6,P15880,Q96JP5,P49427,Q14999,P62081,P62841,P61927,Q13309,Q96BN8,P46777,Q5TAQ9,Q86UK7,O94822,Q13564,Q9BW61,Q9Y3I1,Q9NT62,Q5T4S7,Q7Z6Z7,Q9UJX5,P60866,P49407,O60678,Q9ULT8,Q9UDY8,P31689,Q13501,P62942,Q96FW1,Q9NR09,O75832,Q14258,O75925,O75592,P22681,P60953,P29144,Q96GX5,P52888,Q5T447,P53350,Q6W2J9,Q13618,Q14527,O75155,Q99816 65 +Cell cycle 0.2748856735636828 4.181612825845704 2.8944855702484062e-05 0.1722239591278982 0.0078754128223844 532 Q15648,Q9UPT9,Q15398,O75116,O43670,P35244,Q6P1K2,O75909,Q00535,Q13535,Q12873,Q96DE0,Q9UII4,Q9GZZ1,P42695,Q9ULC4,Q9NVI1,P78362,Q9NRZ9,P50748,P42858,Q68E01,P20248,P08243,Q9UH99,P40763,Q9NYV4,P53985,Q00534,Q13564,Q9Y3I1,Q92908,Q969U7,Q96QE3,Q07864,Q9Y295,Q9Y620,Q9H4L7,P62753,O14976,Q7L2J0,Q9NR09,O75832,Q15003,P27695,Q13464,Q04637,P60953,Q14674,Q92974,P46940,Q7Z7L1,Q8TCY9,Q9BTW9,O95373,P68400,Q92547,Q5TBB1,Q9BY42,Q92905,P42771,Q9BSJ2,Q9Y4A5,Q6IBW4,Q6NUK4,P33992,Q14203,Q69YH5,Q15021,P17612,P35241,Q96L91,Q9Y496,Q14204,P78527,Q9H8V3,P42574,Q9UJX5,Q15418,Q8TEW0,Q8IXJ6,P19784,P14635,Q13315,P11802,O14744,Q9BPX3,P33993,O96017,P35580,Q9BW19,Q9NTI5,Q96GX5,Q99459,Q9H900,Q92538,Q7Z5K2,O00401,Q13618,O00410,O00743,Q9UPP1,P23921,O00299,Q93008,Q08209,Q13526,P62136,P54132,Q2NKX8,Q9BV86,Q99661,Q9UKL3,P52701,Q15058,Q14999,P49427,Q9BUF5,Q15554,Q13885,P83731,Q13309,P61586,P62244,P63172,P18074,P04350,P30307,Q15257,Q29RF7,Q8WUX9,Q96Q89,Q96RU2,Q9NTJ3,O60921,O95067,P28482,Q9BTE3,Q99986,Q7Z460,P53350,Q15334,Q99816,Q13616,P31751,Q9P258,Q9Y5K6,O14965,O14980,P51452,P18858,Q06124,P49917,P50570,Q00610,Q96CW5,Q16513,Q5JVF3,Q9BT25,Q14008,P35579,P40818,P61254,P61289,Q99570,Q9H6H4,Q9H6S0 167 +Organonitrogen compound biosynthetic process 0.2752564483121563 4.153862752281591 3.269093005786594e-05 0.1922278579538431 0.0085388709311148 586 P00374,P41567,Q8WUX2,P67809,P62847,P46782,O75116,O60701,P46776,P62424,P38935,Q13126,Q9H2P9,Q9ULC4,Q9UET6,P53396,P42766,P08243,P20248,P22059,P32969,P40763,P46777,Q14558,O94822,P62917,Q96P11,Q99873,Q92499,Q9BTE6,P84098,P62854,P61313,Q7Z478,Q9Y295,P62753,Q92616,P50914,P62910,P26641,Q8NE71,P47897,Q05639,Q06787,P35790,Q13464,Q04637,P62277,Q99707,P39023,P62899,Q9BQC3,Q14152,P49207,Q01433,P04818,P18621,P11908,P21399,P08708,P17655,P61457,Q8IZH2,Q86W50,Q92905,Q969G6,O43776,Q9P2J5,O60294,Q9UPY5,Q92600,O00178,O15371,Q5TAX3,O95394,P13639,P15531,P12277,P61927,Q9Y2L1,P50336,P49770,Q9BY44,P46778,P27635,P26640,P78527,Q9HCE1,Q86TB9,P36578,O96017,O75592,P62266,Q96JB2,Q9HC07,Q15042,O60841,Q9Y3U8,Q96C86,O15067,A5YKK6,P62701,P15880,P62081,P62269,P62841,P83731,Q02878,Q8N3C0,P62280,P47914,P62750,O00764,P61247,Q14240,O00154,P26373,P49903,P61513,P61803,Q6PKG0,Q9UIV1,Q07020,P09874,P61353,O95352,P30419,P31751,P40429,Q7KZN9,Q13144,P62241,Q02543,P07814,P17812,P26196,P27708,P41252,P46779,Q06210,Q14353,O43505,O60524,P26639,P42345,P60866,P62851,P62906,Q00610,Q9BV10,Q9HD33,P22392,P41214,P18124,P31939,P61254,P63241,P82675,Q99805 159 +Mitotic cell cycle 0.309154127262564 4.130571770109506 3.618620989875865e-05 0.2104564032245278 0.0090883057938038 318 Q9UPT9,Q15398,O75116,O43670,P35244,Q00535,Q9GZZ1,P42695,P50748,P42858,Q68E01,P08243,P20248,Q9UH99,Q00534,Q13564,Q9Y3I1,Q969U7,Q96QE3,Q07864,Q9Y295,P62753,Q7L2J0,Q15003,P27695,Q13464,Q04637,P60953,Q14674,P46940,Q7Z7L1,Q9BTW9,Q92547,Q5TBB1,Q9BY42,P42771,Q9BSJ2,Q6IBW4,Q6NUK4,Q14203,Q69YH5,Q15021,P35241,Q14204,P78527,Q9H8V3,Q9UJX5,Q8IXJ6,P14635,Q13315,P11802,O14744,Q9BPX3,P33993,O96017,P35580,Q9BW19,Q9NTI5,Q96GX5,Q9H900,Q92538,Q7Z5K2,Q13618,O00743,Q9UPP1,P23921,Q08209,Q13526,P54132,Q99661,Q15058,Q14999,P49427,Q9BUF5,Q13885,P83731,Q13309,P61586,P63172,P18074,Q99741,P04350,P30307,Q15257,Q29RF7,Q8WUX9,Q96Q89,Q9NTJ3,O60921,O95067,Q99986,Q7Z460,P53350,Q13616,Q9P258,O14965,P51452,P18858,Q06124,P50570,Q00610,Q96CW5,Q16513,Q5JVF3,Q14008,P40818,P61254,P61289,Q9H6H4,Q9H6S0 110 +Cellular amide metabolic process 0.2877979530126026 4.108310102778794 3.985647205406728e-05 0.2291549891970516 0.0096393615745579 474 P00374,P41567,Q8WUX2,P67809,P62847,P46782,O75116,P46776,P62424,P38935,Q9H2P9,Q9ULC4,Q9UET6,P53396,P42766,P08243,P20248,P22059,P32969,P40763,P46777,O94822,P62917,Q96P11,Q92499,Q9BTE6,P84098,P62854,P61313,Q7Z478,Q9UJ70,Q9Y295,P62753,Q92616,P50914,P62910,P26641,Q8NE71,P47897,Q05639,P27695,Q06787,Q13464,Q04637,P62277,P39023,P62899,Q9BQC3,Q14152,Q9Y223,P49207,P04818,P18621,P21399,P08708,Q8IZH2,Q86W50,Q92905,O43776,Q9NQW7,Q9P2J5,Q9UPY5,Q92600,O00178,O15371,Q5TAX3,P13639,P61927,Q9Y2L1,P49770,Q9BY44,P46778,P27635,P26640,P78527,Q9HCE1,Q86TB9,P42574,P36578,O75592,P62266,P52888,O60841,Q9Y3U8,Q96C86,A5YKK6,P62701,Q9HCL2,P15880,P62081,P62269,P62841,P83731,Q02878,Q8N3C0,P62280,P47914,P62750,P61247,Q14240,O00154,P26373,P61513,Q6PKG0,Q9UIV1,Q07020,P61353,P31751,P40429,Q13144,P62241,Q02543,P07814,P26196,P41252,P46779,O60524,P26639,P42345,P60866,P62851,P62906,P50747,Q9HD33,P41214,P18124,P61254,P63241,P82675,Q99805 130 +Cell projection organization 0.3224044266183148 4.010477812742406 6.05959947643786e-05 0.3267939534929134 0.0136445464072896 261 P00374,Q3SYG4,O15357,Q13614,P10589,Q00535,Q86Y56,Q9UPN3,Q9Y5K8,P42858,Q99873,Q8WUW1,Q9Y3I1,Q9UBB6,Q7KZI7,O14976,O60271,P78559,P57076,P27695,Q13464,Q06787,P60953,Q99707,P46940,Q9P265,Q9UHB6,Q9BPU6,P49841,Q9Y263,Q9Y5Y2,Q14203,P35241,Q9Y496,Q9NT62,Q9HCE1,Q9H4M9,Q8TC07,P42574,Q9P1Y5,Q8TEW0,O60678,Q9BPX3,Q14155,Q13418,O75592,P63167,Q92538,O00401,Q13618,P00492,Q9BRT6,P31146,Q93008,P46109,Q08209,Q01968,Q9Y2A7,Q6DN90,Q7L576,Q14999,P83731,Q9Y296,Q96N67,Q9NZQ3,Q96Q89,Q9UQB8,P09429,Q9H223,P46821,Q15334,Q66K74,Q9P258,Q9Y5K6,O14965,Q96F07,Q06124,P42345,P50570,Q16513,Q16512,Q13555,P35579 83 +Mitotic cell cycle phase transition 0.3868450467011518 3.7199120422752032 0.0001992921708013 0.7278787581150652 0.0418834040765202 135 Q9UPP1,Q15398,P23921,Q13616,O43670,Q92547,Q5TBB1,Q08209,P42771,Q00535,Q9P258,O14965,P49427,P50748,P35241,P83731,Q68E01,P20248,Q13309,Q00534,Q13564,P78527,P18074,Q9Y3I1,Q969U7,P30307,Q96QE3,Q07864,Q9UJX5,P50570,Q8WUX9,Q8IXJ6,P14635,P62753,Q5JVF3,Q13315,P11802,Q7L2J0,O96017,O60921,O95067,P27695,Q04637,Q14674,Q96GX5,P61254,P61289,Q9H900,Q7Z460,Q7Z7L1,P53350,Q13618,O00743 53 +Ncrna metabolic process 0.3032607420681743 3.69163458681331 0.0002228174375509 0.7666369750084956 0.0440908444608349 294 O75569,Q2NL82,Q2VPK5,P08708,Q96FX7,P62847,Q9Y237,Q8IY37,O75607,Q8IZH2,Q86W50,P61353,O15091,P51532,P62424,O43776,Q12789,Q4G0J3,P62241,O60294,Q96DE0,Q9P2D1,Q96HR8,Q9UBP6,P57081,Q9UET6,Q5TAX3,O43709,Q9HAV4,P07814,P62081,P62841,O75818,P42766,Q68E01,O95163,P41252,Q9Y2L1,Q6P1R4,P40763,P46777,Q8TEA1,P26640,P78316,Q96P11,P78527,Q92499,P18074,O43290,P57678,P26639,Q9BTE6,P42345,Q9H9T3,Q8NHU6,Q6P9B9,P62851,Q99575,P62906,Q8IY81,Q9GZR2,P62753,Q5JTH9,Q7Z2T5,Q9UJA5,P50914,Q7L2J0,Q7Z4G4,P18124,P61254,Q8WUA4 71 +Regulation of cell cycle 0.2999352580200152 3.65674364747596 0.0002554396096563 0.8114201447670453 0.0461969203033523 301 Q15648,Q9UPT9,Q15398,O75116,O43670,P35244,O75909,Q00535,Q13535,Q96DE0,Q9UII4,P78362,P50748,Q68E01,P08243,P20248,P40763,Q9NYV4,Q00534,Q13564,Q9Y3I1,Q969U7,Q96QE3,Q9Y295,Q7L2J0,Q9NR09,O75832,P27695,Q04637,P60953,Q14674,P46940,Q7Z7L1,O95373,P68400,Q92547,Q5TBB1,Q92905,P42771,Q9Y4A5,Q14203,Q69YH5,P17612,P35241,Q96L91,Q14204,P78527,Q9H8V3,P42574,Q9UJX5,Q8IXJ6,P19784,P14635,Q13315,P11802,O14744,O96017,Q96GX5,Q99459,Q9H900,Q92538,Q7Z5K2,Q13618,O00410,P23921,O00299,Q13526,P54132,Q15058,Q14999,Q15554,Q13309,P61586,P62244,Q08J23,P18074,Q99741,P30307,Q8WUX9,Q9UIG0,Q96Q89,Q96RU2,O94966,P43034,O60921,Q15382,O95067,Q14166,P53350,Q13620,Q99640,Q9BQG0,Q99816,P31751,Q9P258,O14965,O14980,P51452,Q06124,Q00610,Q16513,Q5JVF3,P61254,P61289,Q99570,Q9H6S0 106 +Regulation of phosphorus metabolic process 0.3083232791532937 3.6255083333526295 0.0002883935959081 0.8479402565549782 0.0461969203033523 261 O75116,Q13614,O75909,Q00535,Q12923,Q9UII4,Q96JP5,P42858,P20248,P22059,P40763,Q9NYV4,Q9Y3I1,P49407,Q08AM6,Q7KZI7,Q92616,O60271,O75832,P47897,Q05639,Q06787,Q13464,Q14147,Q04637,P60953,Q92974,Q99996,P46940,O95373,P36507,P17655,P49841,P42771,Q92990,Q92600,Q69YH5,P78527,Q9H8V3,P42574,Q8TEW0,Q8IXJ6,Q15185,P14635,Q13315,Q9UDY8,P31689,P33993,Q13418,O96017,P63167,Q6PJG6,Q96GX5,Q14738,O00410,P46109,Q13526,P21359,P54132,Q9UNI6,P67870,P30307,Q15257,Q96N67,Q13501,P62942,O60921,O95067,P28482,Q9H223,P53350,P04035,Q15334,Q99816,Q9UIV1,P09874,P31751,P49327,Q9UER7,Q9Y5V3,P14174,P51452,Q8WUA2,Q06124,P42345,Q16512,P22681,Q99570 88 +Mitotic cell cycle process 0.305110772584899 3.5648167290238955 0.0003641105213949 0.9072710606231016 0.0461969203033523 267 Q15398,O75116,O43670,Q00535,Q9GZZ1,P42695,P50748,Q68E01,P42858,P20248,Q9UH99,Q00534,Q13564,Q9Y3I1,Q969U7,Q96QE3,Q07864,Q9Y295,P62753,Q7L2J0,Q15003,P27695,Q13464,Q04637,P60953,Q14674,Q7Z7L1,Q92547,Q9BY42,Q5TBB1,P42771,Q6IBW4,Q6NUK4,Q14203,Q69YH5,Q15021,P35241,Q14204,P78527,Q9H8V3,Q9UJX5,Q8IXJ6,P14635,Q13315,P11802,O14744,Q9BPX3,P33993,O96017,P35580,Q9BW19,Q9NTI5,Q96GX5,Q9H900,Q13618,O00743,Q9UPP1,P23921,Q08209,Q13526,P54132,Q99661,Q15058,Q14999,P49427,P83731,Q13309,P61586,P63172,P18074,Q99741,P30307,Q15257,Q29RF7,Q8WUX9,Q96Q89,Q9NTJ3,O60921,O95067,Q99986,Q7Z460,P53350,Q13616,Q9P258,O14965,P18858,P50570,Q00610,Q5JVF3,Q14008,P40818,P61254,P61289,Q9H6H4 94 +Modification dependent macromolecule catabolic process 0.3328284865833226 3.5343345751262936 0.0004088032437976 0.9307499199427084 0.0461969203033523 198 Q70CQ2,Q9UPT9,P49841,P68400,Q13616,Q9Y263,Q93008,Q15008,Q15369,Q15386,Q9Y5K6,O14965,O14980,Q5TAX3,Q14999,P49427,Q86UV5,Q5VYK3,Q7L5D6,P25787,P62081,Q13309,Q6NTF9,Q8N3C0,P46777,O95260,O94822,Q6GQQ9,Q9Y3I1,O60524,Q5T4S7,Q96S82,Q7Z6Z7,Q8WUX9,P49407,Q8IXJ6,P19784,Q96RU2,O43242,Q9ULT8,Q13501,O75832,Q14258,P78559,O60826,O75925,P22681,P40818,Q5T447,P53350,Q99816 51 +Ncrna processing 0.3116001824211393 3.397306723447322 0.0006805264201021 0.988267004570026 0.0461969203033523 230 O75569,Q2NL82,Q2VPK5,P08708,Q96FX7,P62847,Q9Y237,Q8IY37,O75607,Q86W50,P61353,O15091,P62424,Q4G0J3,P62241,O60294,Q96DE0,Q9P2D1,Q96HR8,Q9UBP6,P57081,Q9UET6,Q5TAX3,O43709,P62081,P62841,O75818,P42766,Q68E01,O95163,Q9Y2L1,Q6P1R4,P40763,P46777,Q8TEA1,P78316,O43290,Q96P11,P78527,Q92499,P18074,P57678,Q9H9T3,Q6P9B9,P62851,P62906,Q99575,Q8IY81,Q9GZR2,P62753,Q5JTH9,Q7Z2T5,Q9UJA5,P50914,Q7Z4G4,P18124,P61254 57 +Positive regulation of phosphorus metabolic process 0.3582520677888396 3.3696503353617997 0.0007526362318339 0.9926757536631138 0.0461969203033523 151 P36507,P17655,O75116,P46109,Q13526,P31751,Q92990,P49327,O75909,Q00535,Q9UNI6,Q9UER7,Q92600,Q9Y5V3,Q69YH5,Q15058,Q96JP5,P14174,P20248,P22059,P61586,P67870,Q06124,Q9H8V3,P42345,Q15257,P49407,Q96N67,Q08AM6,Q7KZI7,Q15185,P14635,Q13315,Q92616,Q9UDY8,Q13501,O75832,O96017,Q05639,Q13418,P63167,Q06787,Q13464,Q14147,Q04637,Q6PJG6,P60953,P28482,Q92974,Q9H223,Q99996,Q15334,P46940,Q16512,Q99570,P53350,Q14738 57 +Regulation of mitotic cell cycle 0.3596647124583724 3.3525301881716905 0.0008007650807357 0.9946523105733044 0.0461969203033523 147 Q9UPT9,Q15398,P23921,O43670,Q92547,Q5TBB1,P35244,Q13526,P42771,Q9P258,O14965,Q69YH5,Q14999,P50748,P51452,P35241,Q68E01,P08243,Q13564,P78527,P18074,Q9Y3I1,Q06124,Q969U7,P30307,Q96QE3,Q9UJX5,Q8IXJ6,Q96Q89,Q16513,P14635,Q5JVF3,Q13315,P11802,O14744,Q7L2J0,O96017,O60921,P27695,Q04637,P60953,Q14674,P61254,P61289,P46940,Q9H900,Q92538,Q7Z7L1,P53350,Q13618,Q9H6S0 51 +Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity 0.9704565801253346 3.316123827502157 0.0009127537604551 0.9974278260611742 0.0461969203033523 2 P42858 1 +Cell cycle process 0.2825968689232054 3.289331367540477 0.0010042571445267 0.9985856627304334 0.0461969203033523 377 Q15648,Q15398,O75116,O43670,Q00535,Q12873,Q13535,Q96DE0,Q9GZZ1,P42695,P50748,P42858,Q68E01,P20248,Q9UH99,P53985,Q00534,Q13564,Q9Y3I1,Q92908,Q969U7,Q96QE3,Q07864,Q9Y295,Q9Y620,Q9H4L7,P62753,Q7L2J0,Q9NR09,Q15003,P27695,Q13464,Q04637,P60953,Q14674,Q7Z7L1,P68400,Q92547,Q5TBB1,Q9BY42,P42771,Q9BSJ2,Q6IBW4,Q6NUK4,Q14203,Q69YH5,Q15021,P35241,Q9Y496,Q14204,P78527,Q9H8V3,Q9UJX5,Q8IXJ6,P19784,P14635,Q13315,P11802,O14744,Q9BPX3,P33993,O96017,P35580,Q9BW19,Q9NTI5,Q96GX5,Q99459,Q9H900,Q7Z5K2,O00401,Q13618,O00743,Q9UPP1,P23921,Q08209,Q13526,P54132,Q9BV86,Q99661,P52701,Q15058,Q14999,P49427,Q15554,P83731,Q13309,P61586,P63172,Q08J23,P18074,Q99741,P30307,Q8WWK9,Q15257,Q29RF7,Q8WUX9,Q9UIG0,Q96Q89,Q96RU2,Q9NTJ3,O94966,P43034,O60921,O95067,Q15019,Q9BTE3,Q99986,Q7Z4H7,Q7Z460,P53350,Q13620,Q15334,Q99640,Q9BQG0,Q9UHD1,Q13616,Q13432,Q9Y570,Q9P258,O00139,O14965,O14980,P61160,P46379,P18858,Q86XI2,Q15645,Q15555,Q14004,Q96QC0,Q06124,Q14676,P50570,Q00610,P07437,Q96CW5,Q16513,Q5JVF3,P09884,P33991,Q9BT25,P62829,Q14008,P35579,P40818,P61254,P61289,Q99570,Q9H6H4,Q9H6S0 150 +Transposition rna mediated 0.942703670546105 3.196911798110788 0.0013890739423814 0.999885731382522 0.0461969203033523 2 Q5TAX3 1 +Cdp choline pathway 0.93345270068636 3.156785618932515 0.0015951857750415 0.9999703153396956 0.0465025138884891 2 P35790 1 +Cellular protein catabolic process 0.2980770622672046 3.1504140648910353 0.0016303921255409 0.9999764208798624 0.0473176025768106 243 Q70CQ2,Q9UPT9,P17655,P49841,P68400,Q9Y263,Q13616,Q93008,Q92990,Q15008,Q15369,Q15386,Q9Y5K6,P49721,O14965,O14980,Q14999,P17612,P49427,Q86UV5,Q5VYK3,Q7L5D6,P25787,P35241,P20618,P62081,Q14997,Q13309,Q6NTF9,Q8N3C0,P46777,Q86UK7,O95260,O94822,Q9BW61,Q6GQQ9,Q9Y3I1,O60524,Q5T4S7,Q96S82,Q7Z6Z7,Q9UJX5,Q8WUX9,P49407,Q8IXJ6,P19784,Q96RU2,O43242,Q9ULT8,Q9UDY8,Q13501,Q13200,P28066,O75832,O96017,P78559,O60826,O75925,Q06787,Q14258,P22681,Q8TAT6,P40818,P49720,P61289,Q5T447,P53350,Q9Y5X3,Q13618,Q99816 70 +Regulation of protein phosphorylation 0.3162795642410346 3.1327275175238603 0.001731901415644 0.9999878614094244 0.0475153413684863 197 P36507,Q9UIV1,O75116,P46109,Q13526,P31751,P42771,P21359,P54132,O75909,Q00535,Q12923,P49327,Q9UII4,Q9UER7,Q92600,Q9Y5V3,Q15058,Q96JP5,P14174,P51452,P42858,P20248,P22059,P23381,Q9NYV4,P61586,Q8WUA2,P67870,P78527,Q9Y3I1,Q06124,Q9H8V3,P30307,P42345,P42574,P49407,Q8TEW0,Q8IXJ6,Q7KZI7,Q96N67,P14635,Q13315,O60271,Q9UDY8,P31689,Q13501,O75832,P47897,O96017,Q13418,O60921,Q06787,O95067,Q04637,Q6PJG6,P28482,Q16512,P22681,Q92974,Q9H223,Q99996,P46940,P53350,P04035,Q15334,O95373,O00410,Q99816 69 +Negative regulation of sister chromatid cohesion 0.9274843330349124 3.130793145565989 0.0017433490902325 0.9999887371888806 0.0475153413684863 2 Q14674 1 +Regulation of transposition 0.9278961250506892 3.1134475185727624 0.0018491539370155 0.9999943629700442 0.0475153413684863 3 Q5TAX3 1 +Transposition 0.9278961250506892 3.1134475185727624 0.0018491539370155 0.9999943629700442 0.0475153413684863 3 Q5TAX3 1 +Glutamate secretion neurotransmission 0.9194270367054604 3.0955721989570484 0.0019643354389691 0.9999973467501554 0.0475153413684863 2 Q15042 1 +Observational learning 0.919427036705457 3.095572198957015 0.0019643354389693 0.9999973467501554 0.0475153413684863 2 P42858 1 +Rna capping 0.91831005143427 3.052785502224761 0.0022672793910296 0.9999996345526988 0.049516168640213 4 O60942 1 +Regulation of protein modification process 0.2663538182467662 3.0334686412252645 0.0024175983616281 0.9999998633757428 0.0509210552177616 337 O75116,O75909,Q00535,Q12923,P26358,Q9H3P2,Q9UII4,Q9NVI1,Q96JP5,P42858,Q01804,P20248,P22059,P46777,Q9NYV4,Q9Y3I1,P49407,Q7KZI7,O60271,O75832,P47897,Q06787,Q13464,Q04637,Q92974,Q99996,P46940,Q9P265,Q9Y3Y2,O95373,P36507,P49841,Q9Y263,P42771,Q92990,O95071,Q92600,Q69YH5,P18615,P61927,P29375,P78527,Q9H8V3,Q7Z6Z7,P42574,Q8TEW0,Q8IXJ6,P14635,O60678,Q13315,Q9UDY8,P31689,Q13418,O96017,O75925,O75592,P63167,Q6PJG6,Q96GX5,Q15042,Q14738,Q13618,O00410,P46109,Q13526,P21359,P15880,P62081,P62841,Q13309,P67870,P30307,Q15257,Q96N67,Q15020,Q13501,P62942,O60921,O95067,P28482,Q9H223,P53350,P04035,Q15334,Q6W2J9,Q99816,Q9UIV1,O95352,P31751,P49327,Q9UER7,Q9Y5V3,P14174,P51452,Q8WUA2,Q06124,P42345,P60866,Q96FW1,Q16512,P22681 101 +Peptidyl amino acid modification 0.2827003569931054 2.963787125159543 0.0030387842196759 0.9999999976608352 0.0534983283304362 275 Q9UPT9,O75116,Q00535,Q13535,P26358,Q9H3P2,Q9GZZ1,Q9H2P9,P78362,P22059,Q99873,P49407,Q7KZI7,Q13464,Q04637,Q5VZE5,Q92974,Q99996,Q9BQC3,Q9P265,P36507,P49841,P68400,Q9Y4A5,Q92600,Q14CX7,P17612,P18615,Q96L91,P78527,Q9GZT9,Q15418,P16402,Q8TEW0,Q8IXJ6,O14929,P19784,O60678,Q13315,O14744,Q15047,O96017,O75925,Q9Y6J9,P49761,Q9Y237,P50579,Q96BP3,Q9BV86,P67870,Q15257,Q96N67,P62942,O15111,P28482,P61803,Q9H223,Q99986,Q7Z460,P53350,Q15334,Q6W2J9,Q6UXN9,Q99816,Q9UIV1,P09874,O00170,P30419,P31751,O14965,P14174,P27708,Q86TU7,Q8WUA2,Q06124,P42345,Q16513,Q16512,P22392,P22681 80 +Positive regulation of excitatory postsynaptic potential 0.8874962697702167 2.9544908507780883 0.003131854396384 0.9999999987285412 0.0534983283304362 2 Q9UQB8 1 +Smad protein complex assembly 0.8836168307967757 2.937184617030917 0.0033120686662178 0.9999999996095432 0.0548884611532926 2 P62942 1 +Response to staurosporine 0.8879163717348622 2.9364236377956026 0.0033202055368377 0.9999999996298136 0.0548884611532926 3 P55212 1 +Lysosomal microautophagy 0.882721575649057 2.9331857263263865 0.0033550312676515 0.9999999997053368 0.0551847712286266 2 Q9Y4P1 1 +Fas signaling pathway 0.8809310653536235 2.9251821473304975 0.0034425465738601 0.99999999983393 0.0556431414042241 2 Q9UKL3 1 +Cellular response to hyperoxia 0.880931065353625 2.9251821473304975 0.0034425465738601 0.99999999983393 0.0556431414042241 2 O95352 1 +Deadenylation dependent decapping of nuclear transcribed mrna 0.8850746268656732 2.9236963904954587 0.0034590194704247 0.999999999850922 0.0557713509675885 3 Q96C86,Q86TB9 2 +Regulation of snrna transcription by rna polymerase ii 0.8791405550581858 2.9171708291403973 0.0035322225895482 0.9999999999077248 0.056477970123772 2 Q7L2J0 1 +Cellular response to dna damage stimulus 0.2843765722793921 2.914437656661098 0.0035632997166226 0.9999999999247272 0.056477970123772 257 Q9UM54,P23921,P09874,Q99504,Q92547,Q7Z4V5,P46063,P35244,P20585,O95071,O75909,P38935,Q13535,P28340,Q96FZ2,Q9Y4A5,Q9ULC4,P57081,P52701,P14174,Q96L91,Q68E01,Q14997,P18858,Q8N3C0,Q9UBB9,Q08945,P78527,Q92499,P18074,Q06124,P49917,Q96QE3,Q07864,Q7Z6Z7,P42574,P36915,Q29RF7,Q9Y620,Q9H4L7,Q96RU2,Q9GZR2,Q13315,Q96FW1,O75832,O96017,P49005,O60921,P09429,P27695,P28482,P29372,Q9NTI5,Q16512,P22681,P61254,P35251,Q7Z7L1,Q86WJ1,P53350,P54277 61 +Trna metabolic process 0.4291849451121227 2.9066976271990588 0.0036526608708278 0.999999999958092 0.0568538780518341 98 Q2VPK5,Q96FX7,O15091,O43776,Q12789,Q9P2J5,O60294,Q9UBP6,P57081,Q9UET6,Q9Y3I0,P07814,O75818,O95163,P41252,Q6P1R4,P23381,P54136,Q8TEA1,Q08J23,P26640,Q9BV44,Q9BQ52,Q92499,Q9H974,P26639,Q9BTE6,Q9H9T3,Q99575,P78346,Q7Z2T5,O95707,Q9UJA5,Q7Z4G4,P47897,P49589,Q9NSD9,Q8WUA4,Q96Q11 39 +Regulation of synaptic transmission gabaergic 0.88107245412549 2.9057390413421578 0.003663868733563 0.99999999996106 0.0568538780518341 3 P27695 1 +Regulation of oocyte maturation 0.8755595344673193 2.901124931987921 0.0037182560366064 0.9999999999727364 0.0573772911684165 2 Q8IXJ6 1 +Positive regulation of cell maturation 0.8755595344673193 2.901124931987921 0.0037182560366064 0.9999999999727364 0.0573772911684165 2 Q8IXJ6 1 +Chemokine c x c motif ligand 2 production 0.8737690241718873 2.8930903316517553 0.0038147156835786 0.9999999999855124 0.0573772911684165 2 P09429 1 +Positive regulation of chemokine c x c motif ligand 2 production 0.8737690241718873 2.8930903316517553 0.0038147156835786 0.9999999999855124 0.0573772911684165 2 P09429 1 +Negative regulation of macrophage migration 0.8737690241718874 2.8930903316517553 0.0038147156835786 0.9999999999855124 0.0573772911684165 2 P30046 1 +Negative regulation of macrophage chemotaxis 0.8737690241718874 2.8930903316517553 0.0038147156835786 0.9999999999855124 0.0573772911684165 2 P30046 1 +Regulation of cellular component biogenesis 0.2914279261266187 2.8881789063680485 0.0038747941361323 0.9999999999902284 0.0573772911684165 233 P49841,Q9UPP1,P31146,P09874,O75116,A5YKK6,P40429,Q8TBX8,Q13535,Q9Y2A7,P26358,Q7L576,Q96DE0,Q8NCA5,Q9P258,Q14203,Q9HCM4,Q86VP6,Q15058,Q9UPN3,P17612,P49427,Q15554,P51452,P35241,P42858,P20248,Q13045,Q14204,P23381,Q9UBB9,Q5T3I0,Q96F07,Q8WUW1,Q9Y6B6,Q9H2G2,Q9NT62,Q9H8V3,Q8TC07,P04350,Q06124,Q9NZJ4,P42345,P50570,Q9P1Y5,Q8WUX9,Q9Y295,Q8IXJ6,P47755,Q13315,Q9Y613,Q9UQB8,Q9BPX3,Q15047,Q14155,Q16512,P63167,P09429,P27695,Q13464,Q06787,Q04637,Q14008,P60953,Q15042,Q99996,Q7Z460,P53350,P46821,Q9BTW9,O00401,Q99816 72 +Dna repair 0.3095269844902105 2.8872212586256625 0.0038866081099639 0.9999999999909568 0.0573772911684165 187 P23921,Q99504,Q92547,Q7Z4V5,P35244,P20585,O95071,P38935,Q13535,P28340,Q9Y4A5,P52701,Q96L91,Q14997,Q8N3C0,Q9UBB9,P78527,P18074,Q07864,Q7Z6Z7,Q29RF7,Q9H4L7,Q96RU2,Q9GZR2,Q13315,P49005,O96017,O60921,P09429,P27695,Q9NTI5,P35251,Q86WJ1,P54277 34 +G2 mi transition of meiotic cell cycle 0.8750783044754876 2.878771634362784 0.0039922730765935 0.9999999999954764 0.0573772911684165 3 P30307 1 +Negative regulation of cellular senescence 0.8774592841306235 2.870116418722377 0.0041032069698236 0.9999999999978144 0.0578635710644538 4 P67809 1 +Protein deubiquitination involved in ubiquitin dependent protein catabolic process 0.8672038197552934 2.863563472424594 0.0041890487615006 0.9999999999987552 0.0586767745003062 2 Q93008 1 +Negative regulation of lipid transport 0.8666069829901505 2.8608740068760845 0.0042247491128408 0.9999999999990148 0.0586767745003062 2 P31751 1 +Immunoglobulin v d j recombination 0.8663085646075751 2.8595289481597335 0.0042427069366903 0.9999999999991244 0.0586767745003062 2 P78527 1 +Somatic diversification of t cell receptor genes 0.8663085646075751 2.8595289481597335 0.0042427069366903 0.9999999999991244 0.0586767745003062 2 P78527 1 +Nk t cell differentiation 0.8642196359295664 2.8501074485405424 0.0043704461984455 0.9999999999996212 0.0590211300242317 2 O14617 1 +Antigen processing and presentation of lipid antigen via mhc class ib 0.8642196359295664 2.8501074485405424 0.0043704461984455 0.9999999999996212 0.0590211300242317 2 O14617 1 +Zinc ion homeostasis 0.8642196359295664 2.8501074485405424 0.0043704461984455 0.9999999999996212 0.0590211300242317 2 O14617 1 +Regulation of nk t cell differentiation 0.8642196359295664 2.8501074485405424 0.0043704461984455 0.9999999999996212 0.0590211300242317 2 O14617 1 +Adaptation of signaling pathway 0.8639212175469939 2.848760649665929 0.0043889885583088 0.9999999999996644 0.0590211300242317 2 P49407 1 +G protein coupled receptor internalization 0.8639212175469939 2.848760649665929 0.0043889885583088 0.9999999999996644 0.0590211300242317 2 P49407 1 +Sperm dna condensation 0.8670628503938909 2.842574465172054 0.0044750775732662 0.9999999999998092 0.0596372582723034 3 Q14997 1 +Nucleotide excision repair dna gap filling 0.8665671641791076 2.8403308575142057 0.0045066765244143 0.999999999999845 0.0598952630234594 3 Q07864,P28340 2 +Cell division 0.2927192313669914 2.830664111077023 0.0046451474165889 0.9999999999999376 0.0598952630234594 220 P67809,O75116,O43670,Q93008,Q13526,P62136,P54132,Q6P1K2,O75909,Q00535,Q2NKX8,Q9P258,Q6NUK4,Q9Y5K6,Q99661,P42695,Q14203,Q9NRZ9,Q69YH5,Q15058,Q15021,Q14999,P50748,O14965,P20248,P18858,Q14204,P61586,Q00534,P63172,Q08J23,P18074,Q99741,P49917,Q9H8V3,P30307,Q9UJX5,Q29RF7,Q8WUX9,Q00610,Q8TEW0,Q8IXJ6,Q96N67,Q96Q89,P14635,Q16513,Q9NTJ3,P11802,Q9BT25,Q9BPX3,Q9NR09,O96017,Q14008,Q15003,P35580,Q13464,Q9BW19,Q9NTI5,O95067,P60953,P35579,P40818,Q14674,Q92974,Q96GX5,Q9BTE3,Q99986,Q9H900,Q7Z460,Q99570,Q7Z5K2,Q9H6H4,P53350,O00401,Q13618,Q99816 76 +Positive regulation of dna demethylation 0.8567852009715289 2.795932406360607 0.0051750222571593 0.999999999999998 0.0604336405235404 3 Q01804 1 +Spindle assembly involved in female meiosis 0.8548187330600168 2.786978719216966 0.0053201972633454 0.9999999999999992 0.0610560424071101 3 O95067 1 +Embryonic body morphogenesis 0.8492987168009519 2.7824999068129466 0.0053941880791159 0.9999999999999996 0.0611505122768503 2 Q7Z460 1 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.8528358208955237 2.7779405489581275 0.0054704626259791 0.9999999999999996 0.0611505122768503 3 P62081,P61254 2 +Positive regulation of attachment of spindle microtubules to kinetochore 0.8567478253933121 2.7759717499516428 0.0055036990371759 0.9999999999999998 0.0611505122768503 4 Q8IXJ6,P14635 2 +Synaptic transmission gabaergic 0.8565263908929905 2.774959567734751 0.0055208570967915 0.9999999999999998 0.0611505122768503 4 P27695 1 +Thyroid hormone mediated signaling pathway 0.8469113697403753 2.7716318278486796 0.0055776082433984 1.0 0.0611505122768503 2 P42785 1 +G0 to g1 transition 0.8469113697403712 2.771631827848654 0.0055776082433989 1.0 0.0611505122768503 2 P23921 1 +Positive regulation of g0 to g1 transition 0.8469113697403712 2.771631827848654 0.0055776082433989 1.0 0.0611505122768503 2 P23921 1 +Regulation of g0 to g1 transition 0.8469113697403712 2.771631827848654 0.0055776082433989 1.0 0.0611505122768503 2 P23921 1 +Protein catabolic process 0.2746402054596154 2.762595504130409 0.0057343782771006 1.0 0.0622806284514888 282 Q70CQ2,Q9UPT9,Q13190,Q15386,P49721,Q86UV5,Q5VYK3,Q7L5D6,Q14997,P46777,O95260,O94822,Q9Y3I1,Q96S82,P49407,O43242,P28066,O75832,Q05639,O60826,P78559,Q06787,Q13464,P49720,P17655,P49841,P68400,Q9Y263,Q92990,Q15369,P17612,P25787,P20618,P35241,Q86UK7,Q9BW61,Q5T4S7,Q7Z6Z7,Q9UJX5,Q8IXJ6,P19784,Q13315,Q9ULT8,Q9UDY8,Q13200,O96017,O75925,O75592,Q8TAT6,Q9Y5X3,Q13618,P28072,Q93008,Q13526,Q16850,Q15058,Q14999,P49427,P62081,O43847,Q13309,Q6NTF9,Q8N3C0,Q96QK1,Q9H7D7,Q8WUX9,Q96RU2,Q13501,O94966,P25789,P53350,Q14790,P04035,Q13620,Q99816,Q9UIQ6,Q13616,Q9UNS2,O95352,Q13330,Q15008,O00487,Q9Y5K6,P22314,O14965,O14980,P60900,P46379,Q6GQQ9,Q9NXV2,O60524,P42345,Q05086,P14735,P25786,O60493,P62829,P63244,Q14258,P22681,P40818,P61289,Q5T447 103 +Positive regulation of meiotic cell cycle 0.8486567164179131 2.758860420873515 0.005800330358785 1.0 0.0626052185832499 3 Q8IXJ6,P30307 2 +Positive regulation of neurotransmitter secretion 0.8421366756192127 2.7498533703220387 0.0059621937801175 1.0 0.0642460814920255 2 Q15042 1 +Phospholipid homeostasis 0.8400477469412064 2.740307527073301 0.0061381721700186 1.0 0.065236273547544 2 Q9HCL2 1 +N terminal peptidyl methionine acetylation 0.8439605454488817 2.7373682372370105 0.0061932924548488 1.0 0.0652519065069781 3 Q5VZE5 1 +Cell cycle phase transition 0.3204583386354865 2.7364420806098173 0.006210752712711 1.0 0.0652519065069781 162 Q9UPP1,Q15398,P23921,Q13616,O43670,Q92547,Q5TBB1,Q08209,P42771,P54132,Q00535,Q13535,Q9P258,O14965,Q15058,P49427,P50748,P35241,P83731,Q68E01,P20248,Q13309,Q00534,Q08J23,Q13564,P78527,P18074,Q9Y3I1,Q06124,Q969U7,P30307,Q96QE3,Q07864,Q9UJX5,P50570,Q8WUX9,Q8IXJ6,Q96RU2,P14635,P62753,Q5JVF3,Q13315,P11802,Q7L2J0,O96017,O60921,O95067,P27695,Q04637,Q14674,Q96GX5,Q99459,P61254,P61289,Q9H900,Q7Z460,Q7Z7L1,P53350,Q13618,O00743 60 +Negative regulation of cellular macromolecule biosynthetic process 0.3393850373538115 2.7291650480245315 0.0063494916065178 1.0 0.0652519065069781 107 P00374,P49841,Q9UIV1,P67809,O75116,Q8IZH2,Q86W50,A5YKK6,P40429,Q13535,Q5TAX3,P07814,P26196,Q9Y2L1,P40763,P31949,Q9HCE1,Q86TB9,Q29RF7,Q06787,Q13464,Q04637,Q6PKG0,Q7Z7L1,Q7Z5K2,Q96C86,P04818 27 +Antigen processing and presentation via mhc class ib 0.8393300533255901 2.716123308575176 0.0066051312097763 1.0 0.0660962267509493 3 O14617 1 +Positive regulation of protein phosphorylation 0.3381815777689881 2.713868678018636 0.0066502523004894 1.0 0.0660962267509493 117 P36507,O75116,P46109,Q13526,P31751,P49327,O75909,Q00535,Q9UER7,Q92600,Q9Y5V3,Q15058,Q96JP5,P14174,P20248,P22059,P61586,P67870,Q06124,Q9H8V3,P42345,P49407,Q96N67,Q7KZI7,P14635,Q13315,Q9UDY8,Q13501,O75832,O96017,Q13418,Q16512,Q06787,P28482,Q04637,Q6PJG6,Q92974,Q9H223,Q99996,P46940,P53350,Q15334 42 +Positive t cell selection 0.8325872873769 2.706126696681161 0.0068073069261558 1.0 0.0660962267509493 2 P42345 1 +T helper cell lineage commitment 0.8325872873769 2.706126696681161 0.0068073069261558 1.0 0.0660962267509493 2 P42345 1 +Cd4 positive or cd8 positive alpha beta t cell lineage commitment 0.8325872873769 2.706126696681161 0.0068073069261558 1.0 0.0660962267509493 2 P42345 1 +T helper 17 cell differentiation 0.8325872873768961 2.706126696681139 0.0068073069261562 1.0 0.0660962267509493 2 Q9UDY8 1 +Regulation of neuron projection arborization 0.8367164179104508 2.7041083905355023 0.0068487944666939 1.0 0.0660962267509493 3 Q9HCE1,Q15334 2 +Positive regulation of smooth muscle cell migration 0.8319904506117529 2.703386243031201 0.0068636937546791 1.0 0.0660962267509493 2 Q96N67 1 +Activin receptor signaling pathway 0.8356339062335701 2.6991271113586244 0.0069521616900734 1.0 0.0663513559818219 3 P67870 1 +Regulation of activin receptor signaling pathway 0.8356339062335701 2.6991271113586244 0.0069521616900734 1.0 0.0663513559818219 3 P67870 1 +Rna decapping 0.8476437838228371 2.696842113020103 0.0070000451483356 1.0 0.0666330828259937 6 Q96C86,Q96DE0,Q9UIV1,Q86TB9 4 +Aggrephagy 0.8346906545335915 2.6947842804153077 0.0070434214796843 1.0 0.066948387572546 3 P42858 1 +Negative regulation of transforming growth factor beta1 production 0.8284094300208854 2.6869248556925145 0.0072113173971382 1.0 0.067657906039242 2 Q9Y5K6 1 +Regulation of transforming growth factor beta1 production 0.8284094300208854 2.6869248556925145 0.0072113173971382 1.0 0.067657906039242 2 Q9Y5K6 1 +Transforming growth factor beta1 production 0.8284094300208854 2.6869248556925145 0.0072113173971382 1.0 0.067657906039242 2 Q9Y5K6 1 +Regulation of dna ligation 0.8281786534166609 2.6647420480219557 0.0077047397218914 1.0 0.0704404474961836 3 Q9UBB9 1 +Methylguanosine cap decapping 0.836208765432477 2.6622567233223036 0.0077618654343418 1.0 0.0705040500518555 5 Q96C86,Q9UIV1,Q86TB9 3 +Negative regulation of neurotransmitter transport 0.8176663682482777 2.637348233872776 0.0083557005384951 1.0 0.0728528276521425 2 P21359 1 +Negative regulation of neurotransmitter secretion 0.8176663682482777 2.637348233872776 0.0083557005384951 1.0 0.0728528276521425 2 P21359 1 +Negative regulation of myosin light chain phosphatase activity 0.8173679498657005 2.6359669751594077 0.0083897896469236 1.0 0.0728528276521425 2 O75116 1 +Negative regulation of bicellular tight junction assembly 0.8173679498657005 2.6359669751594077 0.0083897896469236 1.0 0.0728528276521425 2 O75116 1 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.8149806028051252 2.6249088524328306 0.0086672165599288 1.0 0.074469637021494 2 P42574 1 +Outer ear morphogenesis 0.8191096630958632 2.622727590878576 0.0087228985895442 1.0 0.0746319920762261 3 O75569 1 +Peptidyl diphthamide biosynthetic process from peptidyl histidine 0.8140853476574145 2.6207583636550944 0.0087734422713874 1.0 0.0746319920762261 2 Q9H2P9 1 +Negative regulation of biomineralization 0.8176119402985123 2.615769253333857 0.008902669835763 1.0 0.0750536993970752 3 O75116,Q6W2J9 2 +Negative regulation of peptidyl threonine phosphorylation 0.8173134328358244 2.6143817341785 0.0089389101389736 1.0 0.0752204680508992 3 Q8IXJ6,Q8TEW0 2 +Positive regulation of lipid kinase activity 0.8164179104477617 2.610217840279165 0.0090484582381342 1.0 0.0760072764677276 3 Q05639,Q99570 2 +Response to vitamin a 0.809907490301397 2.6013627575985225 0.0092854209775228 1.0 0.0774378020219975 2 P46821 1 +Regulation of nuclear transcribed mrna poly a tail shortening 0.8165339393323623 2.5901733798064286 0.009592760429459 1.0 0.0793925546316442 4 A5YKK6 1 +Dna metabolic process 0.2635105696098312 2.5893547512272095 0.0096155978473182 1.0 0.0794808277759343 306 P23921,Q99504,Q92547,Q8IZH2,Q93008,Q7Z4V5,P35244,P20585,O95071,P38935,Q13535,P28340,P26358,Q9UBD5,Q9Y4A5,Q96HR8,P78362,P52701,P49427,P15531,Q96L91,Q01804,Q14997,Q8N3C0,Q9UBB9,P78527,P18074,Q07864,Q7Z6Z7,Q29RF7,Q92614,Q9H4L7,Q96RU2,Q9GZR2,Q13315,P49005,O96017,O60921,P09429,P27695,O43913,P28482,Q9NTI5,P35251,Q7Z7L1,Q86WJ1,P54277 47 +Transforming growth factor beta production 0.8105895257124596 2.583068688696815 0.0097925824339704 1.0 0.0803336222284256 3 Q9Y5K6 1 +Negative regulation of transforming growth factor beta production 0.8105895257124596 2.583068688696815 0.0097925824339704 1.0 0.0803336222284256 3 Q9Y5K6 1 +Peptidyl histidine modification 0.8145715138847393 2.5810039730727214 0.0098513448008268 1.0 0.0806964285191713 4 P22392,Q86TU7,Q9H2P9 3 +Dna damage induced protein phosphorylation 0.8137308663360825 2.57707312589985 0.0099640868674328 1.0 0.0813318590554209 4 Q13315 1 +Ampa glutamate receptor clustering 0.8018501939719427 2.56383275682454 0.0103523414043373 1.0 0.0829939474078305 2 Q15334 1 +Regulation of glutamate receptor clustering 0.8018501939719427 2.56383275682454 0.0103523414043373 1.0 0.0829939474078305 2 Q15334 1 +Regulation of long chain fatty acid import into cell 0.8064278442303578 2.5636311329856483 0.0103583563763218 1.0 0.0829939474078305 3 P31751 1 +Regulation of macrophage chemotaxis 0.8092826516925522 2.556244087161339 0.0105808868763177 1.0 0.0839528448388273 4 P28482,P30046 2 +Regulation of macrophage migration 0.8092826516925522 2.556244087161339 0.0105808868763177 1.0 0.0839528448388273 4 P28482,P30046 2 +Neuron projection maintenance 0.7997612652939314 2.554076015310435 0.0106470009599739 1.0 0.0841706008094793 2 P78559 1 +Cap dependent translational initiation 0.7988660101462248 2.5498911803309205 0.0107756547603696 1.0 0.084777139259294 2 Q04637 1 +Methylation 0.3293386017457759 2.547645082983536 0.0108452746143594 1.0 0.0852221940213806 113 Q6UXN9,Q96FX7,P09874,Q86W50,P26358,Q9H3P2,Q69YN4,O60294,Q8NCA5,Q4G0J3,Q9BV86,Q9H2P9,Q9UBP6,Q9GZS3,P57081,Q9NRZ9,Q9UET6,O43709,P18615,P46087,O94776,Q86TU7,Q8NB78,Q8TEA1,Q08J23,Q99873,Q96P11,Q14353,Q8N1G2,P16402,Q8IY81,O60678,Q7Z2T5,Q9UJA5,O14744,Q7L2J0,Q15047,Q7Z4G4,Q99707,Q8WVM0,Q9UIF9,Q9Y3Y2,Q6W2J9,P04818 44 +Response to epinephrine 0.7979707549984993 2.545704320072498 0.0109057520250575 1.0 0.0852868990702101 2 Q8IXJ6 1 +Cellular response to epinephrine stimulus 0.7979707549984993 2.545704320072498 0.0109057520250575 1.0 0.0852868990702101 2 Q8IXJ6 1 +Positive regulation of amyloid beta formation 0.8110194719513792 2.544565863601957 0.0109413675371556 1.0 0.0853609677629948 5 O75116 1 +Regulation of cd4 positive alpha beta t cell differentiation 0.7992846928366046 2.5301670485258274 0.0114008232493569 1.0 0.0881031273563809 3 Q9UDY8 1 +Synaptic vesicle budding 0.7970610130295963 2.519723453494417 0.0117447067602991 1.0 0.089644782367481 3 O14617 1 +Ribosome biogenesis 0.2843936867349384 2.519526137668001 0.0117512915323987 1.0 0.089644782367481 213 Q2NL82,P08708,P46782,P62847,Q9Y237,Q8IY37,O75607,Q86W50,P61353,P62424,P62241,Q9P2D1,Q96DE0,Q9NVU7,Q96D46,Q96HR8,O14980,O43709,Q7Z4Q2,P62081,P62841,O75818,P42766,P83731,Q9NUL7,Q02878,Q9Y2L1,P46777,P27635,P78316,O43290,Q96P11,P78527,P62750,P18074,P57678,P62851,P62906,Q7Z478,Q8IY81,Q9GZR2,P62753,Q5JTH9,P50914,P18124,P39023,P61254,Q9H9L3 48 +Regulation of cytoplasmic translational initiation 0.7955938349564992 2.5128259948814247 0.0119768392484171 1.0 0.0910462867196324 3 P40429 1 +Microtubule based process 0.2779309484383483 2.5110758522064707 0.0120363831091419 1.0 0.091162935968315 231 P49841,Q15398,O75116,O43670,O43933,Q13526,Q00535,Q12873,Q9BSJ2,Q86Y56,P35579,Q9BV86,Q99661,Q14203,Q9UBF2,O14965,O14980,Q8NI35,Q9UPN3,Q15058,Q9BUF5,Q14999,Q15554,Q13885,O60610,P42858,Q9Y496,Q9UH99,Q14204,P61586,P53985,Q9Y678,Q9NZ32,Q9H2G2,P04350,Q96P70,Q15257,O00203,Q9P1Y5,Q8WUX9,Q00610,Q9Y295,Q8TEW0,Q7KZI7,Q96N67,P14635,O43237,Q96Q89,Q96CW5,Q9BT25,Q14155,O60333,O96017,P78559,P57076,O14617,P27695,Q13464,P63167,Q00796,Q9BW19,P60953,O95067,P29372,Q14674,Q92974,Q15334,Q99996,Q16512,Q14008,Q7Z460,P53350,P46821,Q9BTW9,Q66K74 75 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.790510295434192 2.5107350007748015 0.0120480101365938 1.0 0.091162935968315 2 O00170 1 +V d j recombination 0.8142766354875624 2.5089812020166327 0.0121079927602898 1.0 0.091162935968315 8 P09429,P78527,Q13315,P18858 4 +Macromolecule catabolic process 0.2551798105365917 2.5089244329454807 0.0121099387645702 1.0 0.091162935968315 430 Q70CQ2,Q9UPT9,P67809,O75116,Q13614,Q00535,Q13190,Q96DE0,Q15386,P49721,Q86UV5,Q5VYK3,Q7L5D6,Q14997,P46777,O95260,O94822,Q9Y3I1,Q96S82,P49407,O43242,P11216,P28066,O75832,P78559,O60826,Q05639,P27695,Q06787,Q14147,Q13464,P49720,Q9Y2V2,P17655,P49841,P68400,Q9Y263,Q5TBB1,Q8IZH2,Q86W50,Q92990,Q15369,O00178,Q5TAX3,P17612,P25787,P20618,Q9Y2L1,P35573,Q9HCE1,Q5T4S7,Q86TB9,Q7Z6Z7,Q99575,Q8IXJ6,P19784,Q13315,Q9ULT8,Q9UDY8,Q15477,O96017,O75925,O75592,Q96C86,Q6P6C2,Q93008,A5YKK6,Q96HR8,Q14999,P49427,P62081,Q13309,Q6NTF9,Q8N3C0,Q8WUX9,Q96RU2,Q9GZR2,Q13501,Q6PKG0,P53350,P08237,P04035,Q99816,Q9UIV1,Q13616,O95352,Q15008,Q9Y5K6,O14965,O14980,P06737,Q6PGP7,Q96F86,Q6GQQ9,O60524,P42345,Q5JVF3,Q14258,P22681,P40818,P61289,Q99570,Q5T447,Q9HAU5 104 +Meiotic cell cycle phase transition 0.7973103756653223 2.499938081454131 0.0124215014733204 1.0 0.0925940692018065 4 P30307 1 +Retrograde transport vesicle recycling within golgi 0.7967613333923065 2.497347339956922 0.0125126328187175 1.0 0.0930775826707341 4 Q14746 1 +Intracellular distribution of mitochondria 0.7860340196956097 2.489685794871215 0.0127856071928933 1.0 0.0943433677842496 2 O75153 1 +Lung saccule development 0.7854371829304664 2.486875400033145 0.0128870525656612 1.0 0.0945917469292283 2 Q92908 1 +Phosphatidylinositol 3 phosphate biosynthetic process 0.7977535540089213 2.4819525304135865 0.0130664680738052 1.0 0.0950745676527433 5 Q01968,O00443,Q13315 3 +Cardiac conduction system development 0.7887420183576355 2.4805427836327065 0.013118251983939 1.0 0.0950745676527433 3 Q92908 1 +Regulation of cell adhesion 0.3252391461518362 2.478794383871193 0.0131827276180764 1.0 0.0954359327561413 106 P49841,P31146,Q14185,O75116,P46109,Q08209,P42771,Q92990,P21359,Q9P258,Q9HCL2,Q9HCM4,Q15058,Q9UPN3,P51452,P35241,P20248,Q00534,O43290,Q9H2G2,Q06124,P42574,O00203,P50570,P55196,Q9P1Y5,Q13315,Q9UDY8,Q14155,Q13418,P63167,O14617,P09429,Q13464,P60953,Q7Z460,Q9BTW9 37 +Histone h4 r3 methylation 0.7827514174873148 2.4742174559803445 0.013352839377235 1.0 0.096300616667654 2 Q99873 1 +Positive regulation of cell death 0.3233654364537789 2.4536748752580304 0.0141404765747639 1.0 0.099456083587355 122 O75569,P17655,P49841,P09874,O95352,P62136,P42771,P21359,P49327,Q00535,Q13144,Q9UER7,Q9Y5V3,P78362,P49427,P62081,P42858,Q99956,P20248,Q9Y6C9,P78527,Q92908,Q9H8V3,P55212,P42574,Q15257,P50570,O00429,Q8IXJ6,P62753,Q13315,P31689,Q13501,Q14155,O96017,Q05639,P63167,P09429,Q04637,P60953,P61254,P63241,Q7Z7L1,Q14684 44 +Regulation of dna demethylation 0.7871192566486509 2.4517270279658585 0.0142172469287853 1.0 0.0996699720559623 4 Q01804 1 +Axonal transport of mitochondrion 0.7865440029571897 2.448997947585904 0.014325426442777 1.0 0.1002088224686183 4 P27695 1 +Mitochondrion distribution 0.7865034338608347 2.448805451185428 0.0143330842550826 1.0 0.1002088224686183 4 Q9BUK6,O75153,P27695 3 +Ribonucleoside diphosphate catabolic process 0.7817171014355444 2.447321429192636 0.0143922423269506 1.0 0.1004074170886624 3 Q96DE0 1 +Nucleoside diphosphate catabolic process 0.7817171014355444 2.447321429192636 0.0143922423269506 1.0 0.1004074170886624 3 Q96DE0 1 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.7859154810422685 2.4460152111961992 0.0144444906231866 1.0 0.1006643796898706 4 P14174 1 +Histone h3 k4 demethylation 0.7883421861805451 2.437267481316411 0.0147987281750685 1.0 0.102471682484796 5 P29375,Q8NB78 2 +Negative regulation of nucleotide metabolic process 0.7774232875917576 2.4269545537725863 0.0152261630410652 1.0 0.1034060201671581 3 P09874 1 +Positive regulation of clathrin dependent endocytosis 0.7726051924798505 2.4262335924689475 0.0152564468987481 1.0 0.1034060201671581 2 P50570 1 +Lymphoid progenitor cell differentiation 0.777226379404642 2.4260194461532665 0.0152654522880764 1.0 0.1034060201671581 3 P78527 1 +Pro b cell differentiation 0.7772263794046421 2.426019446153261 0.0152654522880766 1.0 0.1034060201671581 3 P78527 1 +Regulation of fatty acid transport 0.7852659693608285 2.4226140231394573 0.0154092891326098 1.0 0.1038417523590736 5 P31751,P07814 2 +Negative regulation of protein polyubiquitination 0.780115586154692 2.4184444882839458 0.0155870236552817 1.0 0.1039665622768027 4 O95071,Q9Y263 2 +Negative regulation of protein k63 linked ubiquitination 0.780115586154692 2.4184444882839458 0.0155870236552817 1.0 0.1039665622768027 4 O95071,Q9Y263 2 +B cell homeostasis 0.7829399068463394 2.4115183327738814 0.0158862531671215 1.0 0.1054420471314248 5 P42574,P14174 2 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.7778533729503012 2.4076679439673727 0.0160547760393632 1.0 0.106218528406324 4 P14174 1 +Dna dealkylation 0.7928248083831984 2.4063613130008914 0.016112320426469 1.0 0.1064913485676546 8 Q8N3C0,Q93008,P27695,Q01804 4 +Endothelin receptor signaling pathway 0.768128916741269 2.404981302393894 0.0161732932513551 1.0 0.1066783888195448 2 P60953 1 +Liver morphogenesis 0.7725373134328375 2.403722498564168 0.016229087575138 1.0 0.1067230028858526 3 Q15648,Q15418 2 +Neuron projection arborization 0.7804890137038094 2.3998126832280757 0.0164034634775203 1.0 0.1076528809127714 5 Q9HCE1,Q15334,Q9UPN3 3 +Dna dealkylation involved in dna repair 0.771173844783009 2.39722870779619 0.0165196089598487 1.0 0.1080892249577276 3 Q8N3C0 1 +Imp salvage 0.7704477611940351 2.3937686844175796 0.0166762621895215 1.0 0.1085753472966804 3 P00492,Q01433 2 +Embryo development 0.2792813592261617 2.3873833552867487 0.0169687866001875 1.0 0.1097090856427965 213 Q9UM54,O75569,Q15648,Q9UPT9,P17655,P67809,O75116,O60701,Q5TBB1,A5YKK6,O43772,P30419,P21359,Q01968,P26358,Q9P2D1,Q9HCM4,P25440,P62081,P20248,Q9NPQ8,P27635,Q99873,Q8WUW1,P78527,Q8IWS0,Q92908,P18074,Q96EK5,Q6GQQ9,P49917,Q07864,P42574,Q8NHU6,Q9P1Y5,Q96Q89,P14635,P62753,Q13315,Q9ULT8,P20290,Q9NR09,Q9HCK8,O60921,O95067,P26373,Q13464,P28482,P35579,P60953,Q9C0E8,P61803,Q7Z460,Q9Y3Y2,Q9Y2X9,Q6W2J9 56 +Positive regulation of neurotrophin trk receptor signaling pathway 0.7636526410026786 2.3836782529294704 0.0171405810814317 1.0 0.1102738861692114 2 Q96F07 1 +Regulation of neurotrophin trk receptor signaling pathway 0.7636526410026786 2.3836782529294704 0.0171405810814317 1.0 0.1102738861692114 2 Q96F07 1 +Positive regulation of connective tissue replacement 0.767761194029857 2.380954808787514 0.0172678301903304 1.0 0.110512965712178 3 O75116,Q13464 2 +Connective tissue replacement 0.767761194029857 2.380954808787514 0.0172678301903304 1.0 0.110512965712178 3 O75116,Q13464 2 +Positive regulation of tissue remodeling 0.767761194029857 2.380954808787514 0.0172678301903304 1.0 0.110512965712178 3 O75116,Q13464 2 +Regulation of connective tissue replacement 0.767761194029857 2.380954808787514 0.0172678301903304 1.0 0.110512965712178 3 O75116,Q13464 2 +Replicative senescence 0.776004577049997 2.3783561950153405 0.0173900184811954 1.0 0.1107515809826218 5 Q13535,Q13315,P42771 3 +Cd4 positive alpha beta t cell differentiation 0.7753263515524899 2.375106789689572 0.0175438736474637 1.0 0.1110092005018784 5 Q9UDY8,P09429,P42345 3 +T cell differentiation involved in immune response 0.7753263515524899 2.375106789689572 0.0175438736474637 1.0 0.1110092005018784 5 Q9UDY8,P09429,P42345 3 +Dna catabolic process exonucleolytic 0.76156371232467 2.37371946733073 0.0176099242381948 1.0 0.1112116105178069 2 Q9GZR2 1 +Telomeric loop disassembly 0.759773202029247 2.3651745757766633 0.0180215736297224 1.0 0.1118639503822125 2 P54132 1 +Telomeric d loop disassembly 0.759773202029247 2.3651745757766633 0.0180215736297224 1.0 0.1118639503822125 2 P54132 1 +Negative regulation of myeloid leukocyte differentiation 0.7686227582014491 2.363563688769714 0.0181001152508013 1.0 0.1121382851876023 4 Q00534 1 +Negative regulation of chromatin binding 0.7679904449089088 2.360534705182912 0.0182486107405595 1.0 0.1128140166054312 4 O14981,Q7Z5K2,Q7L2J0 3 +Negative regulation of interleukin 8 production 0.7670415794201898 2.3559874689956093 0.0184735408649776 1.0 0.1133244582484547 4 P49407 1 +Regulation of cell maturation 0.760597014925378 2.3466959226343236 0.0189407053095378 1.0 0.1138884030122303 3 Q8IXJ6,O14965 2 +Telomerase holoenzyme complex assembly 0.771791839458365 2.338334482150383 0.0193699035797654 1.0 0.1159353532317765 6 Q13535,Q13315 2 +Regulation of cellular amide metabolic process 0.2836349163472391 2.33106223187823 0.0197500784368047 1.0 0.117350329565364 196 P00374,P41567,P21399,Q9UIV1,P67809,O75116,Q8IZH2,Q86W50,A5YKK6,P31751,P40429,Q13144,P62701,Q9UPY5,Q92600,Q9H2P9,O15371,Q5TAX3,P13639,P07814,P26196,P20248,Q9Y2L1,P49770,P40763,P46777,Q9BY44,Q86UK7,P27635,Q96P11,P78527,Q92499,Q9HCE1,Q86TB9,P42345,P42574,Q15418,Q7Z478,Q14240,Q92616,P27695,Q13464,Q06787,Q04637,Q6PKG0,P61254,P63241,Q9BQC3,O60841,Q96C86,P04818 51 +Regulation of ribosome biogenesis 0.7567219979409872 2.3281121050267046 0.0199061516970466 1.0 0.1178325588043272 3 Q96DE0 1 +Regulation of dopamine receptor signaling pathway 0.7517159056997911 2.3266222559734357 0.019985378934479 1.0 0.1178555472385489 2 O14744 1 +Positive regulation of dopamine receptor signaling pathway 0.7517159056997911 2.3266222559734357 0.019985378934479 1.0 0.1178555472385489 2 O14744 1 +T cell selection 0.7558208955223902 2.3237852097617617 0.0201370088292922 1.0 0.1183570365934099 3 P40763,P42345 2 +Positive regulation of calcium ion transport into cytosol 0.7673372825328016 2.316840672370383 0.0205124125467754 1.0 0.1200128433602873 6 P42858 1 +Positive regulation of release of sequestered calcium ion into cytosol 0.7673372825328016 2.316840672370383 0.0205124125467754 1.0 0.1200128433602873 6 P42858 1 +Regulation of membrane protein ectodomain proteolysis 0.7541200286032218 2.315612488260853 0.0205794363722189 1.0 0.1202001068967706 3 Q13464 1 +Negative regulation of b cell proliferation 0.7575192215029428 2.3102297545161017 0.0208754375687296 1.0 0.1217112565391113 4 P42574,Q13315 2 +T helper 1 cell differentiation 0.752435885565202 2.3075130022833488 0.0210262382347325 1.0 0.1220488605600709 3 P09429 1 +T helper 1 type immune response 0.752435885565202 2.3075130022833488 0.0210262382347325 1.0 0.1220488605600709 3 P09429 1 +Regulation of cytoskeleton organization 0.3097755222829294 2.3071674847578088 0.0210454849909096 1.0 0.1220488605600709 141 P17655,P49841,P31146,O75116,Q00535,Q9Y2A7,Q7L576,Q9Y5K6,Q14203,Q8NI35,P35241,O60610,Q13045,Q14204,P61586,Q96F07,Q8WUW1,P04350,Q9H8V3,Q8WWK9,P42345,Q9P1Y5,Q8WUX9,Q00610,Q9Y295,Q9Y696,Q7KZI7,P47755,Q9Y613,Q9UQB8,Q9BPX3,Q14155,Q16512,P78559,O75592,P63167,Q14008,Q13464,P28482,P29372,P60953,Q92974,Q99996,P46940,Q7Z460,Q9UHB6,P53350,P46821,Q9BTW9,O00401,Q66K74 51 +Regulation of modification of synaptic structure 0.7560465810689752 2.3031332118457732 0.0212713491782587 1.0 0.122704867609567 4 Q9UQB8,Q7L576,P60953 3 +Regulation of modification of postsynaptic structure 0.7560465810689752 2.3031332118457732 0.0212713491782587 1.0 0.122704867609567 4 Q9UQB8,Q7L576,P60953 3 +Maintenance of dna methylation 0.755275407061511 2.2994148415382933 0.0214813939719165 1.0 0.1236979741063622 4 P26358 1 +Ribonucleoprotein complex biogenesis 0.2572501486923523 2.297611625465212 0.0215839033965759 1.0 0.1240622512124898 293 Q9Y383,O75569,P08708,P62314,Q2NL82,P46782,P62847,Q9Y237,Q8IY37,O75607,Q86W50,P61353,P40429,Q13535,P62241,Q9P2D1,Q96DE0,Q9NVU7,Q96D46,Q96HR8,Q9ULC4,P78362,O14980,O43709,P62081,P62841,O75818,P42766,P83731,Q9NUL7,Q02878,Q9Y2L1,P27635,P78316,O43290,Q96P11,P78527,P62750,P18074,P57678,P62851,P62906,Q7Z478,Q5JTH9,Q9GZR2,P62753,Q13315,Q9Y312,Q15020,P50914,Q96SB4,P41214,P18124,P39023,P61254,Q14152,Q9H9L3 57 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.7629573847034692 2.295659896365207 0.0216953351574282 1.0 0.1242724022614093 6 P14174,P61254 2 +Peptidyl methionine modification 0.7584996261050341 2.2941260813685234 0.0217832576379557 1.0 0.1245575064587136 5 Q5VZE5,Q14CX7 2 +Negative regulation of muscle organ development 0.7442554461354698 2.290779581403424 0.0219761651637386 1.0 0.1250100030634384 2 Q8IXJ6 1 +Negative regulation of muscle tissue development 0.7442554461354698 2.290779581403424 0.0219761651637386 1.0 0.1250100030634384 2 Q8IXJ6 1 +Retrograde axonal transport 0.771867667029144 2.289367056377902 0.0220580345623178 1.0 0.1251424549886492 9 P78559,Q14204,P27695 3 +Regulation of phosphatidylinositol 3 kinase activity 0.7479224625255767 2.285771858493154 0.0222676088410291 1.0 0.125690692692802 3 Q99570 1 +N terminal protein amino acid acetylation 0.7521870565000346 2.28450900448308 0.0223416340026971 1.0 0.125690692692802 4 Q5VZE5,Q14CX7 2 +Reelin mediated signaling pathway 0.7427633542226211 2.2835942291376625 0.0223953892567072 1.0 0.125690692692802 2 P46109 1 +Maintenance of centrosome location 0.7427633542226166 2.28359422913764 0.0223953892567085 1.0 0.125690692692802 2 Q99996 1 +Maintenance of organelle location 0.7427633542226166 2.28359422913764 0.0223953892567085 1.0 0.125690692692802 2 Q99996 1 +Hypothalamus development 0.7513394062128501 2.2804137237230915 0.0225831624367098 1.0 0.1263650820151804 4 O75569,P27695 2 +Rna guanine n7 methylation 0.7553243756384107 2.278766742983898 0.0226809348379481 1.0 0.1266486804329671 5 P57081,Q9UBP6 2 +Negative regulation of cell aging 0.759448182836981 2.278656037105954 0.0226875200253007 1.0 0.1266486804329671 6 P67809,Q00534 2 +Regulation of organelle organization 0.2506173647347806 2.2772072549371685 0.0227738521109213 1.0 0.1268884422221127 352 Q15398,O75116,O43670,Q00535,Q13535,Q13190,P26358,Q8NI35,P50748,P42858,P22059,Q9Y6B6,Q8WUW1,Q9Y3I1,Q969U7,Q9Y295,Q7KZI7,P47755,Q9Y613,O75832,P78559,Q15003,P27695,Q13464,P60953,Q14674,Q92974,Q99996,P46940,Q9UHB6,Q9BTW9,P36507,P17655,P49841,Q8IZH2,Q14203,Q69YH5,Q15021,P35241,Q13045,Q14204,Q9NT62,Q9H8V3,Q8TC07,Q7Z6Z7,Q9UJX5,Q9P1Y5,O00429,Q8IXJ6,P19784,P14635,Q13315,O14744,Q9BPX3,P33993,Q15047,Q14155,O75592,P63167,Q9C0E8,Q15042,Q9H900,Q7Z5K2,O00401,Q13618,P31146,A5YKK6,Q13526,Q8TBX8,Q9Y2A7,Q7L576,Q96HR8,Q14999,Q15554,O60610,P61586,Q99741,P04350,Q96QK1,P30307,Q8WWK9,Q8WUX9,Q9UIG0,Q96Q89,Q9NTJ3,Q9UQB8,Q13501,P28482,P29372,Q7Z460,P53350,P46821,Q66K74,Q99816,P09874,P30419,P31751,Q9Y5K6,O14965,Q96F07,Q9Y6C9,P49917,P42345,P50570,Q00610,Q5JVF3,Q16512,Q14008 108 +Regulation of protein kinase a signaling 0.7452800505148853 2.2730198085711204 0.0230249862651257 1.0 0.1279601364351242 3 O00170 1 +Intestinal epithelial cell differentiation 0.7439880644369917 2.2667784731244383 0.0234037618042888 1.0 0.1289675650481063 3 Q92908 1 +Positive regulation of activated t cell proliferation 0.743431604784557 2.2640890455835803 0.0235686385952544 1.0 0.1295481565883937 3 Q9HCL2 1 +Heart valve morphogenesis 0.7516430464414728 2.260928525083821 0.0237636834132342 1.0 0.1298588233942993 5 O75116,P20248,P42345 3 +Regulation of cytoplasmic translational elongation 0.7426222295711614 2.2601758776594183 0.0238103373590474 1.0 0.1298588233942993 3 Q9H2P9 1 +Response to amphetamine 0.7425512154191535 2.2598324607499896 0.0238316509391611 1.0 0.1298588233942993 3 P00492 1 +Base excision repair gap filling 0.7624194664042285 2.2589952149822454 0.0238836825262716 1.0 0.1298588233942993 8 P27695,Q07864,P28340 3 +Synaptic vesicle cytoskeletal transport 0.746661159872648 2.2577796891559614 0.0239593981098493 1.0 0.1301621211791317 4 O14617 1 +5 phosphoribose 1 diphosphate metabolic process 0.7452971036130103 2.251170042655987 0.0243747695142479 1.0 0.1316519809164925 4 Q14558,P06737,P11908 3 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.7449985070170099 2.2497225582453377 0.0244665626174354 1.0 0.1320385569354158 4 P40763,P26196,Q04637 3 +Regulation of cell cycle process 0.2782432906705829 2.2468940132269664 0.0246468014206029 1.0 0.1326822862955788 202 Q15648,Q15398,P68400,P23921,O75116,O43670,Q92547,Q5TBB1,Q13526,P42771,P54132,Q13535,Q96DE0,Q9P258,Q14203,O14965,Q69YH5,Q15058,Q14999,Q15554,P50748,O14980,P35241,Q68E01,Q14204,P61586,Q08J23,Q13564,P78527,P18074,Q9Y3I1,Q99741,Q969U7,Q9H8V3,P30307,Q96QE3,Q06124,Q9UJX5,Q8WUX9,Q9UIG0,Q00610,Q9Y295,Q8IXJ6,Q96Q89,P19784,P14635,Q96RU2,Q16513,Q13315,Q5JVF3,P11802,O14744,O94966,Q7L2J0,Q9NR09,O96017,O60921,P27695,Q04637,P60953,Q14674,Q99459,P61254,P61289,Q9H900,Q99570,Q7Z7L1,Q7Z5K2,P53350,Q13620,Q13618,Q99640,Q9BQG0 73 +Negative regulation of signal transduction by p53 class mediator 0.7520793997736865 2.2428533751370217 0.0249062712276759 1.0 0.1336384150507182 6 P14174,Q96QE3 2 +Autophagy of nucleus 0.7433687153266977 2.241818079774731 0.0249731322458361 1.0 0.1337168896339681 4 Q9NT62 1 +Regulation of mitotic cell cycle phase transition 0.3593865535515299 2.241561253564787 0.0249897425296075 1.0 0.1337168896339681 100 Q15398,P23921,O43670,Q92547,Q5TBB1,P42771,P54132,Q9P258,O14965,P50748,P35241,Q68E01,Q13564,P78527,P18074,Q9Y3I1,Q969U7,P30307,Q96QE3,Q9UJX5,Q8IXJ6,P14635,Q5JVF3,Q13315,P11802,Q7L2J0,O96017,O60921,P27695,Q04637,Q14674,P61254,P61289,Q9H900,Q7Z7L1,P53350,Q13618 37 +Positive regulation of cyclin dependent protein kinase activity 0.7472421194692199 2.23956004626328 0.0251194989798138 1.0 0.1340178817197591 5 O75909,P14635,O75832 3 +Microtubule cytoskeleton organization 0.2864082402781866 2.23347771922696 0.025517458024727 1.0 0.1354707324402175 178 P49841,Q15398,O75116,O43670,Q13526,Q00535,Q12873,Q9BSJ2,Q86Y56,Q9BV86,Q99661,Q14203,O14965,O14980,Q8NI35,Q15058,Q9BUF5,Q14999,Q13885,P42858,Q9Y496,Q9UH99,Q14204,P61586,P53985,P63172,Q9H2G2,P04350,Q96P70,Q15257,Q9P1Y5,Q8WUX9,Q00610,Q9Y295,Q8TEW0,Q7KZI7,Q96N67,P14635,O43237,Q96CW5,Q9BT25,Q14155,O96017,P78559,Q16512,O95067,Q14008,Q13464,Q9BW19,P29372,P35579,Q14674,Q92974,Q15334,Q99996,Q7Z460,P53350,P46821,Q9BTW9,Q66K74 60 +Cell projection assembly 0.3352646542116375 2.231379097582327 0.0256560282345892 1.0 0.1360957468496082 102 P49841,Q3SYG4,O15357,Q01968,P18085,P07737,Q9Y2A7,Q86Y56,Q7L576,Q8NCA5,Q9P258,Q9Y5K6,Q14203,Q9Y5K8,P61160,P35241,P42858,P10155,Q9Y496,Q8WUW1,Q9NT62,Q9H4M9,Q8TC07,Q9BZH6,P42345,P50570,Q9BPX3,Q14155,P57076,P63167,P27695,Q13464,Q06787,Q15019,P60953,Q9H223,Q92538,O00401 38 +In utero embryonic development 0.3116107886222034 2.230855216301352 0.0256907210252861 1.0 0.1361691625772065 107 Q15648,P17655,P67809,A5YKK6,O43772,P30419,Q01968,Q9P2D1,Q9HCM4,P20248,Q9NPQ8,Q99873,Q8WUW1,Q8IWS0,P18074,Q92908,Q6GQQ9,Q96EK5,P49917,Q9P1Y5,P14635,Q9ULT8,P20290,Q9NR09,Q9HCK8,O95067,P26373,P28482,P35579,P61803,Q9Y3Y2,Q6W2J9 32 +Snrna transcription by rna polymerase ii 0.74085235640827 2.2296009609442153 0.0257739460082482 1.0 0.1363888715023184 4 Q7L2J0 1 +Snrna transcription 0.74085235640827 2.2296009609442153 0.0257739460082482 1.0 0.1363888715023184 4 Q7L2J0 1 +Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.7311250373022901 2.2273567935420844 0.0259234376211412 1.0 0.1369018867749837 2 P61254 1 +Neuroblast division 0.7357507285038629 2.2268881081854563 0.0259547528066508 1.0 0.1369018867749837 3 Q96N67 1 +Asymmetric neuroblast division 0.7357507285038629 2.2268881081854563 0.0259547528066508 1.0 0.1369018867749837 3 Q96N67 1 +Histone h2a k63 linked ubiquitination 0.7355394588509209 2.2258627983522263 0.0260233728804859 1.0 0.1371530467389614 3 O95071 1 +Ribosome associated ubiquitin dependent protein catabolic process 0.7441032735791555 2.224290761477929 0.0261288878828782 1.0 0.1375058852656266 5 Q8N3C0,O60524,O94822 3 +Positive regulation of cellular component biogenesis 0.3113418517237208 2.222857765958578 0.026225392420841 1.0 0.1375058852656266 120 P49841,O75116,A5YKK6,Q8TBX8,Q13535,Q9Y2A7,P26358,Q7L576,Q8NCA5,Q14203,Q9HCM4,Q86VP6,P49427,P42858,Q14204,P23381,Q8WUW1,P42345,P50570,Q9Y295,Q13315,Q9Y613,Q9UQB8,Q9BPX3,Q15047,Q16512,Q14008,P27695,Q13464,Q06787,Q04637,P60953,Q15042,Q99996,Q7Z460,P46821,O00401,Q99816 38 +Monovalent inorganic anion homeostasis 0.7392951647090401 2.222032906670788 0.0262810818269945 1.0 0.1375058852656266 4 P12277,Q9Y666 2 +Negative regulation of calcium mediated signaling 0.7319402985074654 2.208378843411802 0.0272178753462375 1.0 0.138014382756567 3 P49841,P42345 2 +Negative regulation of calcineurin mediated signaling 0.7319402985074654 2.208378843411802 0.0272178753462375 1.0 0.138014382756567 3 P49841,P42345 2 +Hyaluronan metabolic process 0.7269471799462757 2.2070864238852987 0.0273080220665542 1.0 0.138014382756567 2 Q00610 1 +Regulation of hyaluronan biosynthetic process 0.7269471799462757 2.2070864238852987 0.0273080220665542 1.0 0.138014382756567 2 Q00610 1 +Hyaluronan biosynthetic process 0.7269471799462757 2.2070864238852987 0.0273080220665542 1.0 0.138014382756567 2 Q00610 1 +Mitochondrial fragmentation involved in apoptotic process 0.7354313456181605 2.2032289045988063 0.0275786190219036 1.0 0.1386361679853969 4 Q9NT62,O00429 2 +Positive regulation of anoikis 0.7301883534704147 2.1998567202724972 0.027817062209297 1.0 0.1396198433717983 3 O96017 1 +Purine deoxyribonucleoside triphosphate metabolic process 0.7343820251802402 2.198115904532319 0.0279408474122297 1.0 0.1401334359461294 4 Q96DE0 1 +Nose development 0.724261414503121 2.194032544841422 0.0282330699668165 1.0 0.1411204909543806 2 Q9P2D1 1 +Vascular endothelial cell proliferation 0.7283582089552276 2.190946148450786 0.0284556896510215 1.0 0.1419461065411935 3 P09429,P40763 2 +Positive regulation of vascular endothelial cell proliferation 0.7283582089552276 2.190946148450786 0.0284556896510215 1.0 0.1419461065411935 3 P09429,P40763 2 +Cranial nerve development 0.7325532780691713 2.1891986077835788 0.0285824078056315 1.0 0.1422371298815632 4 Q9P2D1 1 +Positive regulation of ruffle assembly 0.7274626865671671 2.186583051122198 0.028772975753416 1.0 0.1427716806001573 3 Q7L576,Q8NCA5 2 +Protein linear polyubiquitination 0.7224709042076882 2.1853200158160027 0.0288653908105489 1.0 0.1431214897440278 2 Q96EP0 1 +Meiotic chromosome condensation 0.7398110902091035 2.1829553199646585 0.0290391005145731 1.0 0.1436555502728504 6 Q15003,Q9NTJ3,Q15021,P42695 4 +Positive regulation of chromosome condensation 0.7353651104908319 2.181657385342147 0.0291348282364378 1.0 0.1440200063466611 5 Q9BPX3,Q9NTJ3,Q15021 3 +Glucosamine containing compound metabolic process 0.7351260104107815 2.18048823352399 0.0292212900957995 1.0 0.1442303746766886 5 Q9Y223,Q9UJ70 2 +Female meiosis chromosome segregation 0.7296597721850464 2.1750727715746447 0.0296246635132915 1.0 0.1449056574844895 4 Q15003,P53350 2 +Positive regulation of amyloid precursor protein catabolic process 0.7393245872367424 2.1626893331626 0.0305650820721563 1.0 0.1481737089318344 7 P42574,O75116 2 +Histone mrna catabolic process 0.7448545877965135 2.156637954512644 0.0310338848257369 1.0 0.149709481004283 9 Q8IZH2,Q5TAX3 2 +Tyrosine metabolic process 0.7213050678875015 2.156529227821543 0.0310423640550994 1.0 0.149709481004283 3 P61457 1 +Phototransduction visible light 0.7165025365562407 2.156220997817764 0.0310664126872093 1.0 0.1497148891863298 2 P30419 1 +Protein localization to cytoplasmic stress granule 0.7296015217283527 2.153436438011671 0.031284394472077 1.0 0.1501271134695536 5 P67809 1 +Riboflavin metabolic process 0.7159056997911029 2.1533062654363535 0.0312946167109977 1.0 0.1501271134695536 2 Q969G6 1 +Negative regulation of mirna transcription 0.7204295563366929 2.1522485599077017 0.0313777828904227 1.0 0.1502176849519503 3 Q92908 1 +Positive regulation of fibroblast proliferation 0.746836943849099 2.1510386416537304 0.0314731498186398 1.0 0.1505638595719545 10 P49917,P14174,Q5TBB1,P20248,P14635,Q7Z5K2,Q00534,P11802 8 +Constitutive secretory pathway 0.7153088630259632 2.1503906570735953 0.0315243267493925 1.0 0.150588042189856 2 Q7Z392 1 +Regulation of endoplasmic reticulum tubular network organization 0.7286643164134047 2.148839984830751 0.031647086575969 1.0 0.150813964798407 5 Q9C0E8 1 +Transferrin transport 0.7239283906096137 2.147032913936845 0.0317906613777987 1.0 0.1510866221230172 4 P50570 1 +Neurogenesis 0.2548845777377795 2.1466924015301054 0.0318177780999451 1.0 0.1511055207219212 277 P00374,Q9UM54,Q15648,O60701,P10589,Q13614,Q00535,Q9UPN3,P40763,Q00534,Q96P11,Q99873,Q9Y3I1,Q9H9T3,Q9UBB6,Q7KZI7,O14976,O60271,P78559,P27695,Q13464,Q06787,Q04637,P60953,Q99707,Q92974,P46940,Q9P265,Q9BTW9,Q9BPU6,P49841,Q9Y263,Q9BSJ2,P49770,Q9HCE1,Q9H8V3,Q9H4M9,P42574,Q9P1Y5,Q8TEW0,Q8IXJ6,O60678,O14744,Q13418,O75592,O00401,P00492,Q9BRT6,Q93008,P46109,Q08209,Q13526,P21359,Q9Y2A7,Q6DN90,Q7L576,Q9P2D1,Q9H0D6,Q14999,Q13885,P83731,P61586,Q9UBS4,Q9Y296,P18074,Q96N67,Q9NZQ3,Q96Q89,Q9UQB8,P09429,P28482,P46821,Q15334,Q66K74,P31751,Q13144,O14965,P26196,Q96F07,Q06124,P49917,P42345,P50570,Q16512,Q13555 85 +Regulation of transferase activity 0.2788323972779601 2.14434807243601 0.0320050076619329 1.0 0.1516722750739713 185 P36507,P49841,Q13526,P42771,P21359,P54132,O75909,Q00535,Q8TBX8,Q9UNI6,Q9UII4,Q9UER7,Q96HR8,Q9Y5V3,P15880,Q15058,Q96JP5,P62081,P14174,P62841,P51452,P42858,P61927,P20248,P23381,P46777,Q9NYV4,P61586,Q9Y3I1,Q9H8V3,P30307,P42345,P42574,P60866,O00429,Q08AM6,Q7KZI7,Q15185,P14635,Q13315,Q14240,Q92616,Q9UDY8,P31689,O75832,P47897,Q05639,Q16512,O95067,P28482,P22681,P60953,Q96GX5,P46940,Q99570,P53350,P04035,Q15334,O95373,O00410,Q99816 61 +Regulation of lipid kinase activity 0.7277093997962558 2.1441545164617257 0.032020508104706 1.0 0.1516722750739713 5 Q05639,Q99570,P60953 3 +Trna 5 leader removal 0.7354761476217458 2.1437458954862323 0.0320532526190016 1.0 0.1516722750739713 7 O75818,O15091 2 +N acetylglucosamine metabolic process 0.7219590099704407 2.1373797803242223 0.0325671146269594 1.0 0.1534510048217738 4 Q9UJ70 1 +N terminal protein amino acid modification 0.7375541768225273 2.1368387304151355 0.0326111107815381 1.0 0.1535332036073856 8 Q14CX7,Q5VZE5,P30419,P50579,Q9BV86 5 +Regulation of focal adhesion disassembly 0.716716417910451 2.134073092293169 0.032836798096727 1.0 0.1544843599219217 3 P51452,Q6DN90 2 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.7327229374635664 2.130172333253079 0.0331573883067075 1.0 0.1553211948657104 7 P42574,P42771,P53350,O95373,Q9Y3I1 5 +Odontoblast differentiation 0.7096389137570756 2.1226488066929816 0.0337832918414751 1.0 0.1569697576840693 2 P46821 1 +Negative regulation of lipid localization 0.7189053313303757 2.1223934636295296 0.0338047106333165 1.0 0.1569697576840693 4 P31751 1 +Cell junction disassembly 0.7169304269931291 2.1126895095073177 0.0346273517729587 1.0 0.1597997223162064 4 P51452,Q00535,Q6DN90 3 +Phototransduction 0.7169304269931244 2.112689509507297 0.0346273517729605 1.0 0.1597997223162064 4 O96017,Q13432,P30419 3 +Negative regulation of chemotaxis 0.7210062203517975 2.111203297400294 0.0347548415411984 1.0 0.1599631497375193 5 P14174,P30046 2 +Cardiac neural crest cell differentiation involved in heart development 0.711409492308775 2.108038289315062 0.0350276775817803 1.0 0.160664414304309 3 P28482 1 +Locomotory exploration behavior 0.7113432835820934 2.107713052982586 0.035055817547541 1.0 0.160664414304309 3 Q9HB07,Q15334 2 +Negative regulation of cell size 0.7151388474171334 2.1038783145909 0.0353890630677429 1.0 0.1617148928148084 4 P35241,P61586,P42345 3 +Negative regulation of leukocyte chemotaxis 0.7103331410921725 2.102749636687451 0.0354876605985543 1.0 0.1620520445514404 3 P30046 1 +Neurotransmitter gated ion channel clustering 0.707920305865039 2.0908840778273694 0.0365384567294593 1.0 0.1625907660999613 3 Q15334 1 +Dna replication 0.3042317281812051 2.087452375677259 0.0368472617354878 1.0 0.1635707811915264 119 P23921,Q92547,Q9BY42,P46063,P35244,P54132,P38935,Q13535,P28340,Q9UBD5,Q9Y3Z3,P33992,P78362,P49427,Q15554,P20248,P18858,P31949,Q08945,P33316,Q99543,P17096,P49917,Q96QE3,Q07864,Q29RF7,P33993,P49005,O43913,P60953,Q8WTT2,Q9BTE3,P35251,Q7Z7L1,Q7Z5K2,Q9Y5B9 36 +Regulation of notch signaling pathway 0.7157708203337795 2.0853936940151088 0.0370335787843574 1.0 0.1641083623980384 5 Q15334,P49407 2 +Positive regulation of phospholipid biosynthetic process 0.7067442691103965 2.0850956552084563 0.0370606185797672 1.0 0.1641083623980384 3 P17655 1 +Response to redox state 0.7063470412690458 2.083139764351048 0.0372384857285295 1.0 0.164635959246647 3 Q8IXJ6 1 +Establishment of organelle localization 0.2990685762395684 2.082349457188027 0.0373105614938038 1.0 0.1647315527752124 140 Q9UM54,Q15398,Q9NVU7,Q96D46,Q9UBF2,O14980,P62841,P42858,Q9Y496,Q9UH99,Q14204,Q9Y678,Q9Y6B6,Q9NZ32,O94832,O00203,P50570,Q8WUX9,Q8TEW0,Q96N67,P14635,Q13315,Q9Y613,O14617,P27695,P22681,P35579,Q14674,Q7Z460,Q92538,P53350,P46821,Q15334,Q66K74,Q99816 35 +Embryo development ending in birth or egg hatching 0.2969103274850233 2.0820731059703887 0.03733579264354 1.0 0.1647315715961597 146 Q15648,Q9UPT9,P17655,P67809,Q5TBB1,A5YKK6,O43772,P30419,P21359,Q01968,Q9P2D1,Q9HCM4,P25440,P62081,P20248,Q9NPQ8,Q99873,P78527,Q8IWS0,Q8WUW1,Q92908,P18074,Q96EK5,Q6GQQ9,P49917,P42574,Q9P1Y5,Q96Q89,P14635,Q13315,Q9ULT8,P20290,Q9NR09,Q9HCK8,O60921,O95067,P26373,P28482,P35579,P61803,Q9Y3Y2,Q6W2J9 42 +Regulation of synaptic vesicle recycling 0.7149952655813809 2.081564891302099 0.0373822310780069 1.0 0.1648250971906722 5 Q00535,Q13464,Q9Y263 3 +Regulation of cyclic nucleotide phosphodiesterase activity 0.7059701492537351 2.081283656337698 0.0374079502227624 1.0 0.1648272030733055 3 O00170,Q9GZT9 2 +Regulation of cd4 positive alpha beta t cell activation 0.7102160073699963 2.0796280590840865 0.0375596612903188 1.0 0.1650746342992892 4 Q9UDY8 1 +Corpus callosum development 0.7100104799514266 2.078614372617976 0.0376528088785836 1.0 0.1653438223114232 4 Q00535,Q96P11 2 +Regulation of clathrin dependent endocytosis 0.7143443095780567 2.078350132645286 0.0376771221438587 1.0 0.1653438223114232 5 P50570,O00401,Q8IYB5 3 +Regulation of cardioblast differentiation 0.6997911071321918 2.074279519323698 0.0380533587681637 1.0 0.1662129984990697 2 Q92908 1 +Positive regulation of cardioblast differentiation 0.6997911071321918 2.074279519323698 0.0380533587681637 1.0 0.1662129984990697 2 Q92908 1 +Positive regulation of cardiocyte differentiation 0.6997911071321918 2.074279519323698 0.0380533587681637 1.0 0.1662129984990697 2 Q92908 1 +Regulation of cardiocyte differentiation 0.6997911071321918 2.074279519323698 0.0380533587681637 1.0 0.1662129984990697 2 Q92908 1 +Negative regulation of biosynthetic process 0.2371204539949897 2.070449399257536 0.0384102799098324 1.0 0.1673243014084096 339 P00374,Q15648,Q9UIV1,P67809,P09874,O75116,Q8IZH2,Q86W50,Q93008,A5YKK6,P10589,P42771,P40429,P51532,Q00535,Q12873,Q13535,P26358,Q4G0J3,Q9H3P2,Q9UER7,Q9UPT8,Q9Y5V3,Q9UKL3,Q9H1B7,Q5TAX3,O14981,P07814,P26196,Q9Y2L1,P40763,Q8NB78,P31949,Q00534,P29375,P27635,Q9BQ70,Q8IWS0,Q6GQQ9,Q9HCE1,P17096,Q92908,Q86TB9,Q29RF7,Q00610,Q8IXJ6,Q14240,Q13501,Q7L2J0,Q9HCK8,O75832,O75925,O75182,P09429,P27695,P47897,Q06787,Q13464,Q04637,Q6PKG0,Q96KM6,P35251,P85037,Q7Z7L1,Q7Z5K2,P53350,Q8IUF8,Q96C86,Q9Y2X9,Q6W2J9,P04818,Q99816 72 +Neurotrophin trk receptor signaling pathway 0.7155661786674522 2.063535717828896 0.0390617578848671 1.0 0.1690346447900478 6 Q06124,P27695,P42574,Q96F07,Q7L576 5 +Negative regulation of viral entry into host cell 0.7018872656916858 2.06115473428297 0.0392882804207141 1.0 0.1697898551603333 3 Q14258 1 +Negative regulation of viral life cycle 0.7018872656916858 2.06115473428297 0.0392882804207141 1.0 0.1697898551603333 3 Q14258 1 +Heart trabecula morphogenesis 0.7057635952080041 2.0576460209324097 0.0396241255183593 1.0 0.1704516071376065 4 Q9P2D1,P62942 2 +Regulation of protein containing complex assembly 0.3025055356552563 2.054380997537058 0.0399388307766785 1.0 0.1709315527719286 113 P49841,P31146,P09874,P40429,Q13535,Q9Y2A7,Q7L576,Q14203,Q86VP6,Q15058,P35241,Q13045,P23381,Q9UBB9,P61586,Q96F07,Q9Y6B6,Q8WUW1,P04350,Q06124,P42345,Q9P1Y5,Q9Y295,Q8IXJ6,P47755,Q13315,Q9UQB8,Q9BPX3,Q14155,Q16512,P09429,Q14008,Q04637,P60953,Q99996,Q7Z460,P46821,Q9BTW9 38 +Regulation of b cell differentiation 0.6956132497761756 2.0536885510262084 0.0400058453614673 1.0 0.1709673888811398 2 Q5JVF3 1 +5s class rrna transcription by rna polymerase iii 0.7091007669881364 2.0524189288452694 0.0401289664922184 1.0 0.1712051051225991 5 Q12789 1 +Chromosome organization 0.2461491906389294 2.0520341549991787 0.040166343192622 1.0 0.1712051051225991 376 P41567,Q9UPT9,Q9UPP1,Q15398,P09874,Q99504,O43670,O75607,Q8IZH2,P35244,P20585,P46063,P51532,P38935,Q13535,Q12873,P26358,Q9P2D1,Q9Y4A5,Q9UER7,Q9GZZ1,Q96HR8,P42695,P52701,Q15021,O43709,P50748,P25440,Q96L91,Q14839,Q14997,Q8N3C0,Q9UBB9,Q8NB78,P29375,P78527,P18074,P17096,P49917,Q29RF7,Q8WUX9,Q8IXJ6,Q9H4L7,P14635,Q5JVF3,Q9NTJ3,Q13315,Q15020,Q9BPX3,Q96SB4,Q9HCK8,O60921,Q16512,P09429,P27695,O14646,P28482,Q9NTI5,Q9Y6J9,Q14674,Q9BTE3,P35251,Q66K74,Q6W2J9,Q7Z5K2,Q86WJ1,P53350,Q8TEX9,Q7LBC6,Q14527,Q9UKK9 71 +Positive regulation of actin cytoskeleton reorganization 0.702953539936664 2.043748626311994 0.0409783867245776 1.0 0.1736462461463284 4 Q9UQB8,Q00535 2 +Cellular copper ion homeostasis 0.6977247721228461 2.0405927420641867 0.0412913242013266 1.0 0.1747455262700343 3 O60826 1 +Epithelial structure maintenance 0.6917338108027452 2.0345310448577623 0.0418980817857623 1.0 0.1760293251121496 2 Q9Y3F4 1 +Organism emergence from protective structure 0.7007115380149346 2.0326474384868134 0.0420881551280367 1.0 0.1762622105623799 4 Q8IWS0 1 +Female meiosis i 0.7005563698086931 2.031878698511553 0.0421659375069458 1.0 0.1763892196799208 4 O14965,O95067 2 +Histone h3 deacetylation 0.7084332730795591 2.0281432929398653 0.0425456254902663 1.0 0.1776361473474673 6 Q9H4L7 1 +Voluntary musculoskeletal movement 0.699745249294607 2.0278593107445757 0.042574608957187 1.0 0.1776435760322244 4 P78559,P42345 2 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.6992711539087133 2.025509298341772 0.0428150946533039 1.0 0.1780874890924738 4 A5YKK6 1 +Regulation of peptidyl threonine phosphorylation 0.7143108934668518 2.0213578452184553 0.0432427351415247 1.0 0.1793996572262749 8 Q8IXJ6,P28482,P53350,Q8TEW0 4 +Mrna methylation 0.7142405374476979 2.021006450675089 0.0432790973378693 1.0 0.1794228614086936 8 Q8N1G2,Q86W50,Q96FX7,Q69YN4 4 +Growth hormone secretion 0.6936741501493358 2.020544339168642 0.043326955816513 1.0 0.1794228614086936 3 Q9P2D1 1 +Vesicle transport along microtubule 0.7264737330665547 2.0202425457707536 0.0433582351153014 1.0 0.1794228614086936 12 O14617,P27695,P42858,Q9Y496,Q14204 5 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.7067596307083656 2.0198222415560396 0.0434018292233244 1.0 0.1794895154074153 6 P14635 1 +Peptidyl arginine methylation 0.6975433993432151 2.016940726316571 0.0437016993179739 1.0 0.1797696559958497 4 Q99873,O60678 2 +Peptidyl arginine n methylation 0.6975433993432151 2.016940726316571 0.0437016993179739 1.0 0.1797696559958497 4 Q99873,O60678 2 +Peptidyl serine autophosphorylation 0.6929414817694879 2.0169139367747695 0.0437044954087693 1.0 0.1797696559958497 3 Q13315 1 +Posttranscriptional regulation of gene expression 0.2590625887522335 2.013507175394817 0.044061300871881 1.0 0.180216089460576 234 P00374,P41567,P21399,O75569,P36507,Q9UIV1,P67809,O75116,Q8IZH2,Q86W50,A5YKK6,P31751,P40429,Q13144,P62701,Q92600,Q9H2P9,Q96HR8,Q9HCM4,O15371,Q5TAX3,P13639,Q9HAV4,P07814,Q8IWR0,P26196,Q9Y2L1,P49770,P40763,P46777,Q9BY44,P27635,Q96P11,P78527,Q92499,Q9HCE1,Q86TB9,P42345,Q8NHU6,Q7Z478,Q5JVF3,Q14240,Q92616,P27695,Q13464,Q06787,Q04637,Q96C86,Q6PKG0,P61254,P63241,Q9BQC3,O60841,Q9Y2V2,Q6P6C2,P04818 56 +Regulation of microtubule depolymerization 0.7187095390678504 2.010604644012079 0.0443672331460955 1.0 0.180216089460576 10 P78559,Q8WWK9,P29372,Q9P1Y5,Q92974,Q7Z460,P46821,Q66K74 8 +Dna replication synthesis of rna primer 0.6889552238806009 1.997140060926768 0.0458099701207781 1.0 0.1830860160995033 3 P09884,P49642 2 +Positive regulation of lymphocyte differentiation 0.7180923388760472 1.992297400126804 0.0463384367981061 1.0 0.1845229934529688 11 O14617,O00203,Q9UDY8,O43290,P78527 5 +Histone h3 k9 demethylation 0.6923134056235585 1.990961612730921 0.0464851076581565 1.0 0.1847521320801959 4 Q7LBC6 1 +Fatty acid homeostasis 0.7001375540056375 1.9868370222234213 0.0469404604648895 1.0 0.1863350801433001 6 P28340 1 +Purine nucleoside triphosphate catabolic process 0.6908308035452692 1.9835857224360045 0.0473020421495156 1.0 0.1873480017270229 4 Q96DE0 1 +Regulation of cellular macromolecule biosynthetic process 0.2502368159392745 1.9835108955815608 0.0473103912477581 1.0 0.1873480017270229 270 P00374,P41567,P21399,P49841,Q9UIV1,P67809,O75116,Q8IZH2,Q86W50,A5YKK6,P31751,P40429,Q13144,P62701,Q13535,Q9UBD5,Q92600,Q9H2P9,Q96HR8,O15371,Q5TAX3,P13639,P07814,P26196,P20248,Q9Y2L1,P49770,P40763,P46777,P31949,Q86UK7,Q9BY44,P27635,Q99873,Q96P11,Q92499,P78527,Q9HCE1,Q96QE3,Q86TB9,P42345,Q29RF7,Q15418,Q7Z478,Q15185,Q13315,Q14240,Q92616,Q06787,Q13464,Q04637,O43913,P28482,P60953,Q6PKG0,Q15042,P61254,P63241,Q9BQC3,O60841,Q7Z7L1,Q7Z5K2,Q96C86,Q99805,P04818 65 +Dna ligation 0.7059134187255354 1.9793399852596665 0.0477777405618233 1.0 0.1887408625944988 8 P09429,Q9UBB9,P18858 3 +Regulation of gastrulation 0.6852362552069573 1.9786590781469295 0.0478544032425951 1.0 0.1888152587154963 3 Q7Z460 1 +Regulation of long term neuronal synaptic plasticity 0.693983954892634 1.9773088490484831 0.0480067300327169 1.0 0.189187656676911 5 P21359 1 +Snrna modification 0.6934342694696456 1.9745679661018936 0.0483171973544913 1.0 0.1900670474245955 5 Q86W50,Q7L2J0 2 +Axoneme assembly 0.6833998141409934 1.9695214392044111 0.0488932431138726 1.0 0.1910669524437992 3 Q86Y56 1 +Response to cobalt ion 0.6825238560131339 1.9651602057896411 0.049395698150163 1.0 0.192653618636532 3 P42574 1 +Response to glucagon 0.6777081468218349 1.9649737498001072 0.0494172758370889 1.0 0.192653618636532 2 P20248 1 +Positive regulation of protein modification process 0.267636605971221 1.963921975377386 0.0495391409766594 1.0 0.1929984622750044 200 P36507,O75116,P46109,O95352,Q13526,P31751,P49327,O75909,Q00535,P26358,Q9H3P2,Q9UER7,Q92600,Q9Y5V3,Q9NVI1,Q9GZS3,Q69YH5,P15880,Q96JP5,Q15058,P18615,P14174,P20248,P22059,Q13309,P61586,P67870,Q06124,Q9H8V3,Q7Z6Z7,P42345,Q15257,P49407,Q96N67,Q7KZI7,P14635,Q13315,Q15020,Q9UDY8,Q13501,P62942,O75832,O96017,O75925,O75592,Q13418,Q06787,P63167,Q04637,Q6PJG6,P28482,Q16512,Q96GX5,Q92974,Q15042,Q99996,Q9H223,P46940,Q15334,Q9P265,P53350,Q9Y3Y2,Q14738,Q13618 64 +Lymphocyte activation 0.2965558829943473 1.962356920232274 0.049720944585418 1.0 0.1933756808473973 105 Q9P2D1,Q96FZ2,Q9HCL2,Q9NRZ9,P52701,P14174,P51452,P17812,P40763,Q00534,O43290,P78527,Q9Y3I1,Q06124,P49917,P42345,P42574,O00203,Q5JVF3,P62753,Q13315,Q9ULT8,Q9UDY8,P62942,Q16512,P09429,O14617,P35579 28 +Positive regulation of protein sumoylation 0.6864018463197968 1.9615223379218831 0.0498181218274513 1.0 0.1935905811486254 4 O75925 1 +Regulation of chromatin binding 0.6945196799252825 1.958777863101654 0.0501388071518162 1.0 0.1935905811486254 6 O14981,Q7Z5K2,Q7L2J0 3 +Purine deoxyribonucleotide catabolic process 0.6855563111976803 1.957305210245216 0.0503115953041841 1.0 0.1935905811486254 4 Q96DE0 1 +Cellular response to ether 0.6805299839106451 1.9552266091051471 0.0505563291849473 1.0 0.1935905811486254 3 Q6PKG0 1 +Regulation of synapse structural plasticity 0.6753207997612575 1.9530887858952677 0.0508090755381835 1.0 0.19379863508431 2 P60953 1 +Pigment granule maturation 0.6794029850746346 1.9496078632044336 0.0512228754704846 1.0 0.1945813710426205 3 O14617,Q9BXS5 2 +Pigment accumulation 0.6794029850746346 1.9496078632044336 0.0512228754704846 1.0 0.1945813710426205 3 O14617,Q9BXS5 2 +Negative regulation of jun kinase activity 0.6723366159355366 1.9382142958545945 0.0525970833306259 1.0 0.1973902035339208 2 P31689 1 +Myofibroblast differentiation 0.6723366159355277 1.9382142958545507 0.0525970833306312 1.0 0.1973902035339208 2 P09874 1 +Neutrophil homeostasis 0.676810278388462 1.9366708912980877 0.0527855861616064 1.0 0.1978975084084875 3 P09429 1 +Regulation of osteoblast proliferation 0.676748739687853 1.9363636456792257 0.0528231787375181 1.0 0.1978975084084875 3 P20248 1 +Osteoblast proliferation 0.676748739687853 1.9363636456792257 0.0528231787375181 1.0 0.1978975084084875 3 P20248 1 +Neuron development 0.2683072746440935 1.9265909887372668 0.0540306225556217 1.0 0.2008768811646782 192 P00374,Q9BRT6,Q9Y263,O60701,Q93008,P10589,Q13614,Q00535,Q9Y2A7,O14965,Q9UPN3,Q14999,P83731,Q9Y296,Q96F07,Q99873,Q9Y3I1,Q06124,Q9HCE1,P42574,P50570,Q9P1Y5,Q9UBB6,Q8TEW0,Q9NZQ3,Q7KZI7,Q96Q89,Q96N67,O14976,O60271,Q9UQB8,Q16512,P78559,O75592,P09429,Q06787,Q13464,Q13555,P60953,Q99707,Q15334,P46940,Q9P265,P46821,Q9BTW9,Q9BPU6,Q66K74 47 +Protein auto adp ribosylation 0.6699492688749487 1.9263001798486663 0.0540669029927352 1.0 0.2008768811646782 2 P09874 1 +Peptidyl tyrosine dephosphorylation 0.7173963965369576 1.9242594287308843 0.0543220732935809 1.0 0.2013291000049198 16 Q06124,O60942,P30307,Q99504,P51452,Q99956,Q13614,Q9ULE6,Q9UNI6,Q8NCE2 10 +Regulation of protein k63 linked ubiquitination 0.6867354706026668 1.919785620733264 0.0548849838958425 1.0 0.2018877590214673 6 O95071,Q9Y263 2 +Neuron projection regeneration 0.6939687461885816 1.9193126443756297 0.0549447787519876 1.0 0.2018895664788028 8 P00374,Q99707 2 +Gtp biosynthetic process 0.6778142729172786 1.9186180917008089 0.0550326842775297 1.0 0.2018895664788028 4 P22392,P15531,P20839 3 +Atrioventricular canal development 0.6773533444087659 1.9163106807930872 0.0553255621664088 1.0 0.202622501933062 4 Q06124,Q9P2D1 2 +Amino sugar biosynthetic process 0.6765013637221011 1.9120444467201576 0.0558704933738627 1.0 0.2039985645758772 4 Q06210,Q9Y223 2 +Subpallium development 0.6718547161021908 1.911902243756945 0.0558887338478168 1.0 0.2039985645758772 3 Q9UPY5 1 +Striatum development 0.6718547161021908 1.911902243756945 0.0558887338478168 1.0 0.2039985645758772 3 Q9UPY5 1 +Positive regulation of myotube differentiation 0.6669650850492261 1.9113895263544791 0.0559545416563826 1.0 0.2040106962681066 2 P42345 1 +Regulation of cell cycle phase transition 0.2943314367355685 1.9052966293828877 0.0567415233782173 1.0 0.2060863253793011 123 Q15398,P23921,O43670,Q92547,Q5TBB1,P42771,P54132,Q13535,Q9P258,O14965,Q15058,P50748,P35241,Q68E01,Q08J23,Q13564,P78527,P18074,Q9Y3I1,Q06124,Q969U7,P30307,Q96QE3,Q9UJX5,Q8IXJ6,Q96RU2,P14635,Q5JVF3,Q13315,P11802,Q7L2J0,O96017,O60921,P27695,Q04637,Q14674,Q99459,P61254,P61289,Q9H900,Q7Z7L1,P53350,Q13618 43 +Negative regulation of protein metabolic process 0.2463427142620385 1.9049436152551589 0.0567874009056521 1.0 0.2060863253793011 281 P00374,P49841,Q9UIV1,P68400,P67809,Q9Y263,O75116,Q8IZH2,Q86W50,A5YKK6,P42771,P21359,O95071,Q00535,P40429,Q12923,P26358,Q5TAX3,P07814,P62081,P14174,P62841,P51452,P26196,Q9Y2L1,P40763,P46777,P29375,P78527,Q9Y3I1,Q9HCE1,Q86TB9,P42574,Q15257,P60866,P49407,Q8TEW0,Q8IXJ6,P19784,Q5JVF3,O60271,Q96FW1,Q13501,P62942,Q9NR09,P47897,P78559,O75592,Q16512,P27695,Q13464,Q06787,Q04637,P22681,P04035,Q6PKG0,P53350,Q96C86,Q6W2J9,O95373,P04818,Q99816 62 +Protein poly adp ribosylation 0.670149253731348 1.9033655705822623 0.0569928602905012 1.0 0.2060863253793011 3 Q7Z2W4,P09874 2 +Positive regulation of sequestering of triglyceride 0.6648761563712333 1.9009402534642936 0.0573098388081163 1.0 0.2066445319806735 2 Q9BXB4 1 +Regulation of behavior 0.6823931878282286 1.8979785118875936 0.057698912736233 1.0 0.2077033628266824 6 P40763,Q15334,P42345 3 +Self proteolysis 0.6636824828409404 1.8949649006305969 0.0580970518814911 1.0 0.2082183033952749 2 Q14790 1 +Regulation of nmda receptor activity 0.6636824828409283 1.8949649006305345 0.0580970518814993 1.0 0.2082183033952749 2 Q15334 1 +Arf protein signal transduction 0.6772851434737324 1.8937492822777608 0.0582582964982143 1.0 0.2085672566520502 5 Q92538,Q9Y6D5,Q6DN90 3 +Mismatch repair 0.704056735652937 1.8926171873137096 0.0584087964179462 1.0 0.2087626932726815 13 P09429,P52701,P35244,P20585,P54277 5 +Base excision repair 0.7129593929082408 1.8907077496684817 0.0586633673841736 1.0 0.2095578714544059 17 P27695,Q07864,Q7Z6Z7,P29372,P35244,P28340 6 +Platelet morphogenesis 0.683816885173766 1.8862142624724605 0.0592660873325647 1.0 0.2108347687175333 7 Q06124,P78527,P42574 3 +Isopentenyl diphosphate biosynthetic process 0.6665671641791093 1.8854148276459264 0.0593738536846992 1.0 0.211056758062649 3 P53602,Q13907 2 +Nucleoside salvage 0.6754713941062316 1.8846374309631708 0.0594788051186001 1.0 0.2111998898447303 5 P00492,Q13126 2 +Purine ribonucleoside salvage 0.6754713941062316 1.8846374309631708 0.0594788051186001 1.0 0.2111998898447303 5 P00492,Q13126 2 +Oocyte maturation 0.6795331925291631 1.8835939958203956 0.0596199146381604 1.0 0.2112051843787195 6 Q8IXJ6,Q5TAX3 2 +Negative regulation of vascular associated smooth muscle cell migration 0.6612951357803609 1.883004785598769 0.0596997194195181 1.0 0.2112051843787195 2 P61586 1 +Lung secretory cell differentiation 0.6606982990152093 1.8800128058667869 0.0601063326685484 1.0 0.2123887187909207 2 Q92908 1 +Udp n acetylglucosamine metabolic process 0.6745007939650347 1.8797585329326552 0.0601409942469599 1.0 0.2123962641604372 5 Q06210,Q9Y223 2 +Lipid import into cell 0.6821079025104775 1.877596328382216 0.060436408406161 1.0 0.2130938158165397 7 P31751 1 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.6640118170102972 1.8725924170488653 0.0611246892591874 1.0 0.2141798799694973 3 Q99873 1 +Regulation of neurotransmitter receptor activity 0.6638805970149304 1.87193359395343 0.0612157912235094 1.0 0.2142224633920237 3 Q15334,Q99996 2 +Ovulation cycle process 0.6765621123302648 1.868632915674524 0.0616739030514168 1.0 0.2152488438940417 6 P42574 1 +Histone arginine methylation 0.6628177871595511 1.8665961357651717 0.0619580076380028 1.0 0.2156031955583984 3 Q99873 1 +Germinal center formation 0.6626576571982858 1.865791750567142 0.0620705069441456 1.0 0.215710702685083 3 Q16512 1 +Rrna base methylation 0.6758855883089615 1.8652237111118737 0.0621500533055174 1.0 0.2157605973201447 6 Q86W50,Q96P11,O43709 3 +Vascular associated smooth muscle cell migration 0.6614925373134386 1.8599373335636968 0.0628943925749552 1.0 0.217186876528005 3 P61586,Q96N67 2 +Negative regulation of jnk cascade 0.6702757238166813 1.8584976674386664 0.0630983743211694 1.0 0.2175461374431028 5 P51452,P31689,P43034 3 +Glutamate secretion 0.6603323079826969 1.8541046366154263 0.0637241915057158 1.0 0.2190122061513319 3 Q15042 1 +Mitotic nuclear membrane disassembly 0.6603117718909077 1.8540013721470805 0.0637389636863963 1.0 0.2190122061513319 3 Q99986 1 +Inositol phosphate catabolic process 0.664462905427422 1.8515969576557203 0.0640837202512412 1.0 0.2196675555068793 4 Q01968 1 +Positive regulation of catabolic process 0.2826634333350287 1.848991584603841 0.0644590278818526 1.0 0.2203055194499426 155 Q96EP0,Q9UIV1,P67809,O75116,O95352,Q86W50,A5YKK6,P31751,Q5TAX3,P42858,Q9Y2L1,Q9Y3I1,Q9HCE1,Q86TB9,Q7Z6Z7,O00443,Q8IXJ6,Q13315,Q9ULT8,Q9P0V3,O75925,O60826,P09429,Q6PKG0,Q15042,P53350,Q96C86 27 +Spermatid nucleus differentiation 0.6682434823622281 1.8482582107151249 0.0645649980209026 1.0 0.2203055194499426 5 Q14997 1 +Cell migration involved in gastrulation 0.6589109190191422 1.8469551778181907 0.0647536366922874 1.0 0.2206442783453403 3 Q9HCM4 1 +Positive regulation of reproductive process 0.6796197717974573 1.846813794369773 0.0647741319430348 1.0 0.2206442783453403 8 Q8IXJ6,Q8IY37,O14965,P30307 4 +Gamete generation 0.2901498220269019 1.83834996879751 0.0660108523810589 1.0 0.2232703018683111 107 Q93008,Q4G0J3,P52701,O14965,Q5TAX3,P25440,Q14997,Q8NB78,Q96RD7,Q14353,P30307,P42345,O00203,Q8NHU6,Q8IXJ6,P19784,O95248,P62753,Q13315,Q96SB4,O95067,P53350,Q6P6C2 23 +Dephosphorylation 0.3542978886811908 1.8340949812120253 0.0666398962958005 1.0 0.2248881254840195 98 P49841,O15357,Q99504,O75116,Q8TF05,Q08209,Q13614,Q13526,P62136,Q01968,Q12923,Q9UNI6,Q96DE0,Q69YH5,P51452,P42858,Q99956,Q9ULE6,Q5TFE4,P67870,P63151,Q06124,O60942,Q96P16,P30307,P42345,Q15257,O95248,Q9H0R4,P62942,P63167,Q13555,Q13464,Q96GX5,P46940,Q14738,Q8NCE2,O00743 38 +Dtmp metabolic process 0.6554527042311076 1.829543055889822 0.0673182954195312 1.0 0.2263713804334819 3 P04818 1 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.6554527042311076 1.829543055889822 0.0673182954195312 1.0 0.2263713804334819 3 P04818 1 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.6554527042311076 1.829543055889822 0.0673182954195312 1.0 0.2263713804334819 3 P04818 1 +Negative regulation of epidermal growth factor activated receptor activity 0.6551551021291684 1.828043470389347 0.0675430278469959 1.0 0.2264147699388519 3 Q99816 1 +Regulation of epidermal growth factor activated receptor activity 0.6551551021291684 1.828043470389347 0.0675430278469959 1.0 0.2264147699388519 3 Q99816 1 +Hindlimb morphogenesis 0.6579855066131952 1.818947715202408 0.0689194072298002 1.0 0.2297313574326676 4 Q9P2D1 1 +Embryonic hindlimb morphogenesis 0.6579855066131952 1.818947715202408 0.0689194072298002 1.0 0.2297313574326676 4 Q9P2D1 1 +Diencephalon development 0.6664674558012068 1.8176676654977628 0.0691149426546577 1.0 0.2302655997627119 6 O75569,P27695 2 +Neuron differentiation 0.2535766215700662 1.8122843788891567 0.069942266986871 1.0 0.2324636249235337 223 P00374,Q9UM54,Q15648,Q9BRT6,Q9Y263,O60701,Q93008,P10589,Q13614,Q00535,Q9Y2A7,O14965,Q9UPN3,Q14999,P83731,P26196,P40763,Q9Y296,Q96F07,Q99873,P18074,Q9Y3I1,Q06124,Q9HCE1,P42574,P50570,Q9P1Y5,Q9UBB6,Q8TEW0,Q9NZQ3,Q7KZI7,Q96Q89,Q96N67,O14976,O60271,Q9UQB8,Q16512,P78559,O75592,P09429,Q06787,Q13464,Q04637,Q13555,P60953,Q99707,Q92974,Q15334,P46940,Q9P265,P46821,Q9BTW9,Q9BPU6,Q66K74 54 +Rescue of stalled ribosome 0.6652854085749015 1.811686681109196 0.0700346227529928 1.0 0.2324636249235337 6 Q8N3C0,O60524,O94822 3 +Activation induced cell death of t cells 0.6565279465088547 1.8115891943739209 0.0700496958117171 1.0 0.2324636249235337 4 Q9HCL2,P62753 2 +Positive regulation of oligodendrocyte differentiation 0.6605841186959825 1.8095917375015325 0.070359122191326 1.0 0.2330366493790611 5 O14744,P42345 2 +Histone h4 deacetylation 0.6599732074098512 1.806502692292285 0.0708398539845909 1.0 0.2340003459753571 5 Q9H4L7 1 +T cell homeostasis 0.6668294510451451 1.800293682400498 0.0718142779372594 1.0 0.2359612869730424 7 P42574,Q9HCL2,O95067,P62753 4 +Organelle assembly 0.2504822835947258 1.7993825015802465 0.0719581956229746 1.0 0.2361241293557912 238 P49841,Q3SYG4,Q15398,P46782,Q9UIV1,O43670,Q8IY37,A5YKK6,O95352,Q01968,Q9BSJ2,A1X283,Q86Y56,Q14203,O14965,Q9Y5K8,P50748,P35241,P62841,P46087,P42858,P83731,Q13045,Q9NUL7,Q9Y496,Q14204,P46777,Q02878,Q9Y520,P27635,Q96F86,P78527,P62750,Q9NT62,Q8TC07,Q86TB9,P50570,Q8WUX9,Q7Z478,Q9Y295,Q96CW5,Q9BT25,Q9BPX3,O96017,P57076,O95067,P27695,P26196,P62266,Q9Y4P1,P50851,P39023,Q15042,Q9H223,Q7Z460,Q92538,P53350,Q99816 58 +Proteolysis 0.2383333961929968 1.7983253354274538 0.07212546711744 1.0 0.2362274614905737 399 Q70CQ2,Q9UPT9,O75116,Q00535,Q96DE0,Q96FZ2,Q15386,P49721,Q86UV5,Q5VYK3,Q7L5D6,Q01804,Q14997,P20248,P40763,P46777,O95260,O94822,Q9Y3I1,Q96S82,P49407,O43242,Q9NR09,P28066,O75832,P78559,O60826,Q06787,Q13464,Q14674,P49720,Q86TI2,Q6P2Q9,P17655,P49841,P68400,Q9Y263,Q92905,Q92990,Q9H4A4,Q15369,Q9Y4A5,P25787,Q5T4S7,Q7Z6Z7,P55212,P42574,Q8IXJ6,P19784,Q9ULT8,Q9UDY8,O75925,Q9Y4P1,Q9Y6J9,P52888,Q9NY33,Q93008,P50579,Q9UKL3,Q14999,P49427,P62081,Q13309,Q6NTF9,Q8N3C0,Q8WUX9,Q96RU2,Q15020,Q13501,P09429,P53350,Q99816,Q13616,P09874,P49327,Q15008,Q9Y5K6,O14965,O14980,Q96BN8,Q96F07,Q6GQQ9,O60524,Q5JVF3,Q96FW1,Q14258,P22681,P35579,P40818,P29144,P42785,P61289,Q5T447 93 +Cellular response to amyloid beta 0.6537951261723289 1.797781098939679 0.0722117037329665 1.0 0.2362437000883125 4 Q00535,P09874 2 +Response to amyloid beta 0.6537951261723289 1.797781098939679 0.0722117037329665 1.0 0.2362437000883125 4 Q00535,P09874 2 +Regulation of chromosome condensation 0.6698221499563428 1.7970792215401712 0.0723230438737134 1.0 0.2363711093570314 8 Q15003,Q15021,Q9UIG0,Q7Z5K2,Q9NTJ3,Q9BPX3 6 +Trna 5 end processing 0.6730715073224163 1.79601828717504 0.0724916086852114 1.0 0.2366851023572153 9 O75818,O15091 2 +Negative regulation of dna dependent dna replication 0.648640594476922 1.7951722837078097 0.0726262549336258 1.0 0.2368990810579158 3 Q7Z7L1 1 +Regulation of alpha beta t cell differentiation 0.6692228754801711 1.7940313405537285 0.0728081666443076 1.0 0.2373626201634194 8 Q9UDY8,P09429,O14617 3 +Deoxyribonucleoside monophosphate biosynthetic process 0.6570518790701261 1.7917210960908287 0.0731776535118884 1.0 0.2381251752117014 5 P04183,P04818 2 +Fructose 1 6 bisphosphate metabolic process 0.6608703326922617 1.7893233230214356 0.0735627600360602 1.0 0.2388686340305685 6 P08237,P04075,P17858,P09972 4 +Cell morphogenesis 0.2632927243001952 1.787969840424039 0.0737808737978085 1.0 0.2391212610997424 189 Q15648,P49841,P00492,Q9BRT6,P31146,Q9Y263,Q14185,Q93008,P46109,Q08209,Q00535,Q9Y2A7,Q7L576,Q9P258,Q9UL63,Q9HCM4,O14965,Q15058,Q9UPN3,Q14999,P35241,P83731,O60610,Q6XZF7,Q96F07,Q5VZL5,P78527,Q06124,Q9HCE1,Q9H8V3,P42574,O00203,P50570,Q8TEW0,Q96N67,Q7KZI7,Q96Q89,O60678,O60271,Q15020,Q9UQB8,Q14155,Q13418,Q16512,P78559,O75592,P63167,P35580,Q13464,P35579,P60953,Q92974,Q15334,P46940,Q9P265,P46821,Q9BTW9,Q9BPU6,Q13618,Q66K74,O00401 61 +Mrna catabolic process 0.287983759677502 1.787697350152804 0.0738248494923059 1.0 0.2391212610997424 111 Q9HCE1,P27695,Q5TAX3,Q14147,P67809,Q86TB9,O75116,Q8IZH2,Q86W50,Q96C86,Q9Y2L1,Q13315,Q9Y2V2,Q96DE0,Q6P6C2,Q15477 16 +Positive regulation of peptidyl threonine phosphorylation 0.6551835795741032 1.7822590922437431 0.074706990369066 1.0 0.2405506149457599 5 P28482 1 +Oligodendrocyte development 0.6656156987408984 1.7756715439784283 0.0757870702482579 1.0 0.2423553225862509 8 Q13144,Q96P11,P18074 3 +Ventricular trabecula myocardium morphogenesis 0.6447219047797024 1.775358193944145 0.0758387622475667 1.0 0.2424019175118015 3 Q9P2D1 1 +Negative regulation of transcription by rna polymerase ii 0.2808708174359174 1.773815542226202 0.0760936664234497 1.0 0.2428600399536298 150 Q15648,P67809,P09874,Q93008,A5YKK6,P10589,P51532,Q12873,P26358,Q4G0J3,Q9H1B7,Q9Y5V3,P40763,Q8NB78,Q00534,P29375,P27635,Q8IWS0,Q9BQ70,Q6GQQ9,Q8IXJ6,Q13501,Q7L2J0,Q9HCK8,O75925,O75182,P09429,P35251,P85037,P53350,Q9Y2X9,Q6W2J9,Q99816 33 +Response to pain 0.64378491073171 1.7706159921616107 0.076624580753821 1.0 0.2438394309563604 3 P42345 1 +Behavioral response to pain 0.64378491073171 1.7706159921616107 0.076624580753821 1.0 0.2438394309563604 3 P42345 1 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6386153387048632 1.7687783391663128 0.0769308729110389 1.0 0.2443378405199826 2 Q9UNN5 1 +Single strand break repair 0.6562302576487717 1.7657807082644508 0.0774326462697874 1.0 0.2454539709425785 6 P49917,Q15554,P09874 3 +Protein k48 linked ubiquitination 0.6732567069130024 1.764094865125608 0.0777160088554875 1.0 0.2458747760786501 11 O95071,Q15386,P49427,Q13309 4 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.6503238149099598 1.7576158915706193 0.0788128875385998 1.0 0.2483823144918228 5 Q13535,Q13315 2 +Dna ligation involved in dna repair 0.6356311548791254 1.7536702666088697 0.0794870231718254 1.0 0.250251723991784 2 P49917 1 +Modification of postsynaptic actin cytoskeleton 0.6495074598991339 1.7534719500123557 0.0795210302117843 1.0 0.250251723991784 5 Q9UQB8,Q7L576,P61586 3 +Regulation of long term synaptic potentiation 0.6529089522150741 1.7489049009595612 0.0803074592915598 1.0 0.2518939949028838 6 Q13501,P21359 2 +Peroxisome proliferator activated receptor signaling pathway 0.6484701094345824 1.7482044351321206 0.0804286339008442 1.0 0.2518939949028838 5 Q96EK7 1 +Cell differentiation in spinal cord 0.6344374813488475 1.7476221671003112 0.0805294743039459 1.0 0.2519681203664433 2 Q6Y7W6 1 +Spinal cord motor neuron differentiation 0.6344374813488475 1.7476221671003112 0.0805294743039459 1.0 0.2519681203664433 2 Q6Y7W6 1 +Cell differentiation involved in embryonic placenta development 0.6388059701492619 1.745388730229445 0.0809172260511721 1.0 0.2524555595385351 3 Q14790,Q9ULT8 2 +Negative regulation of cell junction assembly 0.6515185631497866 1.741834323033972 0.0815374388973588 1.0 0.2539053295182419 6 O75116,Q9P258,Q13464 3 +Purine nucleoside biosynthetic process 0.6504605094815522 1.736451472962312 0.0824840376955018 1.0 0.2562420390826008 6 P00492,Q13126 2 +Intraciliary retrograde transport 0.6317517159056956 1.7340039014691733 0.082917390926207 1.0 0.2572211699516068 2 Q8NCM8 1 +Ventral spinal cord development 0.6346268656716472 1.7241778406066957 0.0846757431950273 1.0 0.2613479667616781 3 Q14203,Q6Y7W6 2 +Rrna metabolic process 0.2632757456978196 1.7239776053439329 0.0847118860631068 1.0 0.2613479667616781 180 Q2NL82,P08708,P62847,Q9Y237,Q8IY37,O75607,Q8IZH2,Q86W50,P61353,P51532,Q12789,P62241,Q9P2D1,Q96DE0,Q96HR8,O43709,P62081,P62841,O75818,P42766,Q9Y2L1,P78316,O43290,Q96P11,P78527,P18074,P57678,P42345,P62851,P62906,Q5JTH9,Q9GZR2,P62753,P50914,P18124,P61254,Q8WUA4 37 +Purine containing compound salvage 0.6549391224416555 1.7211949297144251 0.0852154575882764 1.0 0.2622322987989844 8 P00492,Q01433,Q13126 3 +Cellular response to leucine starvation 0.6379139672346388 1.717254676726516 0.0859326492825331 1.0 0.2632588536798545 4 Q92616,P42345 2 +Rrna methylation 0.6609583431814341 1.7171313367017005 0.0859551777044465 1.0 0.2632588536798545 10 O43709,Q86W50,P46087,Q8IY81,Q96P11 5 +Response to interleukin 4 0.6540624508437354 1.7167131099086912 0.0860316035975337 1.0 0.2632588536798545 8 P49327,P39023,P33993,P11802 4 +Regulation of long term synaptic depression 0.6281706953148203 1.715824911189776 0.0861940932875235 1.0 0.2632588536798545 2 Q06787 1 +Regulation of keratinocyte migration 0.63750373245744 1.7151683772868933 0.0863143608139562 1.0 0.26337980192296 4 Q15555,Q6DN90,P42345 3 +Keratinocyte migration 0.63750373245744 1.7151683772868933 0.0863143608139562 1.0 0.26337980192296 4 Q15555,Q6DN90,P42345 3 +Regulation of mitochondrial fusion 0.6369025599585741 1.712110499155914 0.0868763068774811 1.0 0.2644765892354088 4 Q7Z6Z7 1 +Establishment of golgi localization 0.636788383682962 1.7115296662985358 0.0869833795419552 1.0 0.2646791558289691 4 Q9Y678 1 +Cytoplasmic translational elongation 0.6404177378867277 1.7072498594670056 0.0877756212944154 1.0 0.2669654434338764 5 O60524,Q9H2P9 2 +Lymphocyte homeostasis 0.6617115475771742 1.704743027456266 0.0882423612689393 1.0 0.2681352345677869 11 O95067,P42574,P14174,P49327,P62753,Q9HCL2 6 +Udp n acetylglucosamine biosynthetic process 0.6303409785807107 1.7023916013296927 0.0886819834038652 1.0 0.2690470089263274 3 Q06210 1 +Somatic stem cell population maintenance 0.6346954765558188 1.700878640995835 0.0889657781584944 1.0 0.2694822241631795 4 Q9Y6J9 1 +Centriole centriole cohesion 0.6298632573175695 1.69996117293086 0.0891382290581801 1.0 0.2696750965402209 3 Q9Y496 1 +Purine ribonucleotide salvage 0.6432731588219748 1.6998342715268682 0.0891621031286886 1.0 0.2696750965402209 6 P00492,Q01433 2 +Purine nucleotide salvage 0.6432731588219748 1.6998342715268682 0.0891621031286886 1.0 0.2696750965402209 6 P00492,Q01433 2 +Termination of rna polymerase ii transcription 0.6248880931065205 1.6991398837130962 0.0892928301229947 1.0 0.2699454540292386 2 Q9UNY4 1 +Positive regulation of catalytic activity 0.2531549268987171 1.6973185149955932 0.0896364586604689 1.0 0.2707336147330538 212 P00374,P36507,P49841,Q9Y263,O75116,P20585,P21359,Q969G6,P31751,O75909,Q00535,P49327,Q9UNI6,Q9HAD4,Q9P258,Q9UER7,Q96HR8,Q9UKL3,Q9Y5V3,P52701,P15880,Q96JP5,P14174,P20248,Q14997,P40763,Q96F07,Q8TC07,P42345,Q15257,P55196,Q96N67,Q08AM6,Q7KZI7,P14635,Q92616,Q9UDY8,O75832,Q16512,Q05639,P09429,Q13464,P28482,P60953,Q15042,P61289,P46940,Q99570,Q86X10,P53350,Q9Y3Y2,Q15334 52 +Meiotic cell cycle checkpoint signaling 0.6337798266929251 1.696216391183363 0.0898449074053733 1.0 0.2710661303005969 4 Q08J23,O60921 2 +Regulation of t circle formation 0.6239928379588124 1.694586004005359 0.0901539839744809 1.0 0.2715431343880813 2 Q15554 1 +Activation of nf kappab inducing kinase activity 0.6376280171932095 1.6930348250220049 0.0904488386264632 1.0 0.2721801457284816 5 Q96JP5 1 +Cellular response to interferon alpha 0.6283506810742991 1.692263200242746 0.0905958010230147 1.0 0.2724613163735619 3 P10155 1 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.62339600119367 1.691549279619719 0.090731944200622 1.0 0.272655129144069 2 P78310 1 +Sensory perception of pain 0.63244254213194 1.6894046797769846 0.091141904799332 1.0 0.2733838485712623 4 Q9BPW8 1 +Uterus development 0.6227991644285245 1.6885119148309344 0.0913130037369556 1.0 0.2737713105612122 2 Q6KC79 1 +Regulation of b cell proliferation 0.6513678685360678 1.684997617072174 0.0919890312512099 1.0 0.274210238811605 9 Q16512,Q13315,P14174,P42574 4 +Ribonucleoprotein complex subunit organization 0.2821564044643376 1.679252172801171 0.0931029078059451 1.0 0.276849721299099 127 O75569,P62314,Q13535,Q96HR8,Q9ULC4,P78362,P62841,P83731,Q02878,Q9NUL7,Q9UBB9,P27635,O43290,P78527,P62750,P57678,Q7Z478,Q13315,Q9Y312,Q96SB4,P39023,Q14152 22 +Extracellular matrix disassembly 0.6388875846587069 1.6774484640016678 0.0934548191450233 1.0 0.2776144325648005 6 A1X283,Q9BPX3 2 +Alpha beta t cell differentiation 0.6563540939470484 1.677130220990846 0.093517020336908 1.0 0.2776144325648005 11 P09429,O14617,P42345,O00203,Q9UDY8 5 +Activation of phospholipase d activity 0.6253445780598691 1.6769522931642542 0.0935518111360815 1.0 0.2776144325648005 3 P18085 1 +Positive regulation of glucose import 0.6297235760956196 1.6755456903797816 0.0938272143231664 1.0 0.2782432831654299 4 P31751 1 +Trabecula morphogenesis 0.6340861666552471 1.674968415673078 0.0939404287749552 1.0 0.2783262250002076 5 Q9P2D1,Q15648,P62942 3 +Pyroptosis 0.6294835017923325 1.6743213947135829 0.0940674519548236 1.0 0.2785595574317206 4 P55212 1 +Positive regulation of cilium assembly 0.6420376364247493 1.673943214133392 0.0941417601302747 1.0 0.2785595574317206 7 P42858 1 +Pre mirna processing 0.6377044420838183 1.6714038522805426 0.0946419355345562 1.0 0.2792642743066661 6 O75569 1 +Radial glial cell differentiation 0.6235820895522446 1.6679682064428554 0.0953220383678092 1.0 0.2807636042137097 3 P40763,P61586 2 +Protein localization to endosome 0.6403114623247531 1.665107547820019 0.095891301156433 1.0 0.2819809458922644 7 O75116,P35241 2 +Nucleoside triphosphate catabolic process 0.6362445375309129 1.6639422063797606 0.0961239794113599 1.0 0.2819809458922644 6 Q96DE0,Q9Y3Z3 2 +Deoxyribonucleoside triphosphate catabolic process 0.6362445375309129 1.6639422063797606 0.0961239794113599 1.0 0.2819809458922644 6 Q96DE0,Q9Y3Z3 2 +Negative regulation of cytokine production involved in inflammatory response 0.6177260519247962 1.662668862560717 0.0963787383511656 1.0 0.2824147069411735 2 Q53EL6 1 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6397014177733258 1.6619838450342943 0.0965160136860285 1.0 0.2824964452576273 7 P14174,Q96QE3 2 +Copper ion homeostasis 0.6261946573738393 1.657539799204112 0.097410389358167 1.0 0.2845965754386428 4 O60826 1 +Negative regulation of cilium assembly 0.6205605687013498 1.6525541398118848 0.0984216380369991 1.0 0.286916650170359 3 P50570 1 +Body morphogenesis 0.6372532081906777 1.6494422028838982 0.0990570747379546 1.0 0.2880097781270623 7 Q06124,Q7Z460,Q15042 3 +Response to amine 0.6290846869794066 1.6494218086720809 0.0990612498734122 1.0 0.2880097781270623 5 P00492,Q08209,P23378 3 +Response to isoquinoline alkaloid 0.6194029850746342 1.6466447969320417 0.0996310770011033 1.0 0.2891515256965353 3 P06744,P63151 2 +Biological process involved in intraspecies interaction between organisms 0.6282055894093146 1.6449274462600747 0.099984774121081 1.0 0.2897916444787659 5 Q9HCK8 1 +Astrocyte development 0.6220368775122258 1.6362992815604174 0.1017769663992949 1.0 0.2943328567703258 4 P21359,Q00534 2 +Regulation of protein kinase activity 0.2800432878438029 1.6341640552040404 0.1022244078096132 1.0 0.2951040596802718 114 P42771,P21359,O75909,Q00535,Q9UII4,Q9UER7,Q9Y5V3,Q96JP5,P14174,P51452,P42858,P20248,Q9NYV4,Q9Y3I1,P30307,P42345,P42574,Q7KZI7,P14635,Q9UDY8,O75832,P47897,Q16512,O95067,P22681,P46940,P53350,P04035,Q15334,O95373,Q99816 31 +Multicellular organism reproduction 0.2799040548090101 1.6334363851959064 0.1023772498182107 1.0 0.2954146890468034 126 Q93008,Q4G0J3,P52701,O14965,Q5TAX3,P25440,Q14997,Q8NB78,Q96RD7,Q14353,Q06124,P30307,P42345,P42574,O00203,P50570,Q8NHU6,Q8IXJ6,P19784,O95248,P62753,Q13315,Q96SB4,O75592,O95067,P53350,Q6P6C2,Q9H6S0 28 +Meiotic chromosome separation 0.6289151202708457 1.6264315031781762 0.103857893687993 1.0 0.2983589853087691 6 Q15003,Q14674 2 +Pathway restricted smad protein phosphorylation 0.6200721909399485 1.6262529746420766 0.1038958510153733 1.0 0.2983589853087691 4 P67870 1 +Interleukin 6 mediated signaling pathway 0.6151282830339825 1.6248041089691012 0.1042043052565904 1.0 0.2989692940797607 3 P40763 1 +Imp biosynthetic process 0.6380956428902275 1.6167405535192891 0.1059342961803968 1.0 0.3026032169982465 9 P00492,O15067,Q01433,P31939 4 +Negative regulation of protein modification process 0.2777875793335098 1.613614549148428 0.1066110590536206 1.0 0.3035941897479359 133 P49841,Q9Y263,O75116,P42771,Q92990,O95071,Q00535,P21359,Q12923,P26358,P62081,P51452,P62841,P61927,P46777,P29375,P78527,Q9Y3I1,P42574,Q15257,P60866,P49407,Q8TEW0,Q8IXJ6,O60678,O60271,Q96FW1,P31689,Q13501,P62942,P47897,Q16512,Q13464,Q04637,P22681,Q96GX5,P53350,P04035,Q6W2J9,O95373,O00410,Q99816 42 +Platelet derived growth factor receptor signaling pathway 0.6299472529703033 1.6119630090368555 0.1069699894683395 1.0 0.3036840853169396 7 Q06124,P46940,O00443 3 +Regulation of polysaccharide metabolic process 0.6299112112019885 1.6117779290181398 0.1070102726361834 1.0 0.3036840853169396 7 P49841,Q00610,P31751,P62136 4 +Positive regulation of alpha beta t cell differentiation 0.6297469248823733 1.6109342708903005 0.1071940494044283 1.0 0.3039414427316183 7 O00203,Q9UDY8,O14617 3 +Regulation of nitric oxide synthase activity 0.6254444567406695 1.608641535199601 0.1076947465697224 1.0 0.3049262123851782 6 P00374 1 +Trna methylation 0.6566535905431932 1.608227091653044 0.1077854517942022 1.0 0.3049262123851782 16 P57081,Q96FX7,Q8TEA1,Q7Z2T5,Q9UJA5,O60294,Q7Z4G4,Q9UBP6 8 +Response to human chorionic gonadotropin 0.6069829901521903 1.6077986849658106 0.1078792765632257 1.0 0.3049262123851782 2 P48507 1 +Regulation of hepatic stellate cell activation 0.6069829901521839 1.6077986849657782 0.1078792765632328 1.0 0.3049262123851782 2 Q15418 1 +Gmp salvage 0.615786141177598 1.6043161591934263 0.1086443809900372 1.0 0.3067219229852759 4 P00492 1 +Regulation of glucan biosynthetic process 0.6191145180623797 1.598381234255592 0.109958158390353 1.0 0.3092847154310913 5 P49841,P31751 2 +Regulation of glycogen metabolic process 0.6191145180623797 1.598381234255592 0.109958158390353 1.0 0.3092847154310913 5 P49841,P31751 2 +Cerebellar granular layer morphogenesis 0.6045956430916074 1.5955802430782726 0.1105825414388133 1.0 0.3107160049894367 2 Q15058 1 +Cerebellar granular layer development 0.6045956430916074 1.5955802430782726 0.1105825414388133 1.0 0.3107160049894367 2 Q15058 1 +Threonine catabolic process 0.6042972247090392 1.5940523257988457 0.1109243155887775 1.0 0.3108737256629689 2 O75600 1 +Energy homeostasis 0.6367586937271422 1.5924499531605414 0.111283639745277 1.0 0.3116132793896479 10 P40763,P42785,Q13501,Q01433 4 +Regulation of myeloid cell apoptotic process 0.6221542316081936 1.5917608788199458 0.1114384434683097 1.0 0.311779364116565 6 P14174,P42771 2 +Myeloid cell apoptotic process 0.6221542316081936 1.5917608788199458 0.1114384434683097 1.0 0.311779364116565 6 P14174,P42771 2 +Histone threonine phosphorylation 0.612768169388668 1.5888534191716397 0.1120934896749705 1.0 0.312970016832723 4 Q99986 1 +Oocyte differentiation 0.641425045143763 1.5841343263738763 0.1131631543676605 1.0 0.3148510430425323 12 O14965,Q5TAX3,Q8NHU6,Q8IXJ6,Q13315 5 +Pigment granule organization 0.6160118616735428 1.5824684833261822 0.1135426616407233 1.0 0.3152353658647634 5 O00203,O14617 2 +Regulation of rac protein signal transduction 0.6101188684172627 1.5752689842317786 0.115194369940506 1.0 0.3188720795724901 4 P21359 1 +Regulation of translational termination 0.6122305433233981 1.563057550073917 0.1180390590689457 1.0 0.3244833273649172 5 Q8N543,P63241 2 +Macrophage migration 0.6163905869168466 1.562155582952717 0.1182513413967811 1.0 0.3244833273649172 6 P28482,P30046 2 +Macrophage chemotaxis 0.6163905869168466 1.562155582952717 0.1182513413967811 1.0 0.3244833273649172 6 P28482,P30046 2 +Protein retention in golgi apparatus 0.5980304386750157 1.5619356994629705 0.1183031374094945 1.0 0.3244833273649172 2 Q5THJ4 1 +P body assembly 0.6271111681392465 1.5600708159731675 0.1187431472662667 1.0 0.3248398624418609 9 Q9UIV1,Q86TB9,A5YKK6,P26196,Q14204 5 +Telomere maintenance in response to dna damage 0.6149251385039413 1.5546215290823966 0.120036233272933 1.0 0.3278279394697835 6 P27695 1 +Negative regulation of muscle cell differentiation 0.6293936138217471 1.5543516380944966 0.1201005623997173 1.0 0.3278665018687935 10 P67809 1 +Regulation of cell adhesion mediated by integrin 0.6057940534760831 1.5530728669289222 0.1204057274353791 1.0 0.3280094835021258 4 Q06124 1 +Phosphatidylcholine biosynthetic process 0.6184620420127289 1.5528986521029575 0.1204473488760058 1.0 0.3280094835021258 7 O96017,P35790 2 +Regulation of protein polyubiquitination 0.625711342028175 1.5528387372567083 0.1204616656575117 1.0 0.3280094835021258 9 O95071,Q13309,Q9Y263 3 +Histone lysine demethylation 0.6254133151751685 1.5512987286170865 0.1208301113831569 1.0 0.3280094835021258 9 P29375,Q8NB78,Q7LBC6,Q9UPP1 4 +Superoxide metabolic process 0.6181379117702877 1.551229399273326 0.120846719089033 1.0 0.3280094835021258 7 P00374 1 +Telomere maintenance via semi conservative replication 0.6097316292081623 1.5502195853427536 0.1210888205375899 1.0 0.3280094835021258 5 Q15554,P54132 2 +Regulation of t cell migration 0.6046902664087559 1.5474040320953475 0.1217658495705589 1.0 0.3289743474123913 4 P46109 1 +Methionine biosynthetic process 0.6089239768994469 1.5460686802027352 0.1220879818281786 1.0 0.3291637164896805 5 Q13126 1 +Positive regulation of podosome assembly 0.6042696561064055 1.545243454114428 0.122287387189218 1.0 0.3294293062481823 4 Q9BPX3 1 +Regulation of podosome assembly 0.6042696561064055 1.545243454114428 0.122287387189218 1.0 0.3294293062481823 4 Q9BPX3 1 +Response to hepatocyte growth factor 0.6075518220103011 1.539014719037611 0.1238007029176708 1.0 0.3325456972654836 5 Q8IXJ6 1 +Positive regulation of protein metabolic process 0.2244401972310433 1.5371611142946475 0.1242538601493559 1.0 0.3333849033432065 341 P67809,O75116,O75909,Q00535,Q13190,P26358,Q9H3P2,Q9NVI1,Q96JP5,Q14997,P20248,P22059,P40763,P46777,Q96P11,Q99873,P49407,Q7Z478,Q7KZI7,O75832,O60826,Q06787,Q04637,Q92974,Q99996,P46940,Q9P265,Q9Y3Y2,P36507,P49841,P68400,Q92600,Q69YH5,O15371,P13639,P18615,P78527,Q7Z6Z7,P42574,Q8IXJ6,P14635,Q13315,Q9ULT8,Q9UDY8,O96017,O75925,O75592,Q15042,P62701,Q9UKL3,P15880,Q13309,P67870,Q96P70,Q15257,Q96N67,Q15020,Q13501,P62942,P09429,P28482,Q6PKG0,Q9H223,P53350,Q15334,O95352,P31751,P49327,Q13144,Q9UER7,Q9Y5V3,O14965,P14174,Q96F07,Q06124,P42345,Q16512,P35579,P61254,P61289,P63241 81 +Establishment of mitochondrion localization 0.6205157320121973 1.525977745818324 0.1270154068391209 1.0 0.3390885554617578 9 Q9NZ32,P27695,P46821 3 +Intestinal hexose absorption 0.5908683974932804 1.525163985997878 0.1272182008445217 1.0 0.3394021514077527 2 Q14651 1 +Visual behavior 0.6166687674749668 1.5244922076132494 0.1273858019545692 1.0 0.3394143694645856 8 P04035,Q9NPQ8,Q00535,P21359 4 +Negative regulation of meiotic cell cycle 0.5893763055804165 1.5174948271721995 0.1291417985269092 1.0 0.3414646242566062 2 Q15645 1 +Heart valve development 0.6146693403812465 1.5141653201533012 0.1299839150307811 1.0 0.3428255083020471 8 O75116,Q9ULT8,P20248,P42345 4 +Regulation of skeletal muscle contraction by calcium ion signaling 0.5884810504327027 1.512892011864622 0.1303070913219097 1.0 0.3432453837563819 2 P28161 1 +Positive regulation of ryanodine sensitive calcium release channel activity 0.5884810504327027 1.512892011864622 0.1303070913219097 1.0 0.3432453837563819 2 P28161 1 +Regulation of cellular response to heat 0.6206332536478091 1.508961081011463 0.1313087288763583 1.0 0.3451876004680435 10 P49841,P42345,Q13535,Q13315,Q99543 5 +Negative regulation of protein localization to cell surface 0.5875857952849823 1.5082882246260714 0.1314807756555858 1.0 0.3455007907569317 2 Q9HD26 1 +Positive regulation of molecular function 0.227934089533234 1.507376909271837 0.1317140740195748 1.0 0.3459746192066868 312 P00374,P36507,Q96EP0,P49841,Q9Y263,P09874,O75116,Q92905,P20585,P21359,P31751,P49327,O75909,P51532,Q00535,Q9UNI6,Q969G6,Q9HAD4,Q9P258,Q9UER7,Q96D46,Q96HR8,Q9UKL3,Q9HCM4,P52701,P15880,Q9Y5V3,Q96JP5,P14174,P15531,P42858,Q14997,P20248,P40763,Q9UBS4,Q96F07,P18074,Q8NFQ8,Q8TC07,P42345,Q15257,P50570,P55196,Q96N67,Q08AM6,Q8IXJ6,Q7KZI7,P14635,Q92616,Q9UDY8,P62942,O15111,Q14258,Q16512,O75832,P09429,Q05639,P27695,P28482,Q06787,Q13464,Q04637,P60953,Q15042,P61289,Q92974,Q99996,P46940,Q99570,Q86X10,P53350,Q9Y3Y2,Q15334 73 +Activated t cell proliferation 0.6056542520495897 1.5069011825406773 0.1318359883029694 1.0 0.3459872999910282 6 P42574,Q9HCL2 2 +Methionine metabolic process 0.60479001105024 1.5024479279414145 0.1329814664353774 1.0 0.348557026023154 6 Q13126 1 +Synaptic vesicle recycling via endosome 0.5912001964009106 1.5020577653799527 0.1330821910620043 1.0 0.3485867258864374 3 O14617 1 +Modification of postsynaptic structure 0.6084877465630775 1.5014788433918898 0.1332317547603099 1.0 0.3487083310504715 7 Q9UQB8,P60953,O95793,P07737,P61586,Q7L576 6 +Regulation of microvillus length 0.5910447761194086 1.5012580915116065 0.1332888199543609 1.0 0.3487083310504715 3 Q14651,Q6IBS0 2 +Regulation of cell projection size 0.5910447761194086 1.5012580915116065 0.1332888199543609 1.0 0.3487083310504715 3 Q14651,Q6IBS0 2 +Nucleotide sugar biosynthetic process 0.6083375938295854 1.5007039902967292 0.1334321405415104 1.0 0.348803794129729 7 Q9NR45,O60701,Q06210 3 +T cell activation involved in immune response 0.6118522969028753 1.4996089415584766 0.1337157301492137 1.0 0.3491258368150204 8 Q9UDY8,P09429,P62753,P42345 4 +Positive regulation of protein polyubiquitination 0.5996471115352604 1.4983363340220583 0.1340458885362132 1.0 0.3497082110033849 5 P98170,Q13309 2 +Mitotic dna replication checkpoint signaling 0.5991486896163193 1.4957691561341722 0.1347138216262109 1.0 0.3507501017620245 5 O60921,Q92547,Q13564 3 +Dna replication checkpoint signaling 0.5991486896163193 1.4957691561341722 0.1347138216262109 1.0 0.3507501017620245 5 O60921,Q92547,Q13564 3 +Exit from mitosis 0.6175347475859532 1.4928896725369256 0.1354660689249542 1.0 0.3524276613864348 10 Q8IXJ6,P83731,Q8WUX9,P50748 4 +Regulation of skeletal muscle adaptation 0.5885573817576601 1.4884562369500052 0.1366306151796892 1.0 0.3545235883076589 3 Q13555 1 +Skeletal muscle adaptation 0.5885573817576601 1.4884562369500052 0.1366306151796892 1.0 0.3545235883076589 3 Q13555 1 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.6020600321788004 1.4883760788668066 0.1366517414656014 1.0 0.3545235883076589 6 Q16512,Q13309,P09874 3 +Cellular response to stress 0.2148582471226972 1.48691313824652 0.1370377538015643 1.0 0.354820195211822 499 P00374,Q9UM54,P67809,O75116,P35244,P46063,Q9BYN0,O75909,P38935,Q13535,Q96FZ2,Q9ULC4,Q5VYK3,Q7L5D6,Q68E01,P08243,Q14997,P20248,Q00534,Q08945,Q0VDF9,Q99873,Q92499,Q9Y3I1,Q92908,Q96QE3,Q07864,Q9Y620,Q9H4L7,Q92616,O75832,P47897,P27695,Q06787,Q04637,P60953,Q99707,Q92974,P35251,Q7Z7L1,Q86WJ1,P54277,O75569,P36507,P49841,Q99504,Q92547,Q5TBB1,Q7Z4V5,Q92905,P42771,O95071,P28340,Q9P2J5,Q9UPY5,Q9Y3Z3,Q9Y4A5,Q96L91,Q99956,Q9UBB9,P78527,Q7Z6Z7,P42574,P36915,Q8IXJ6,Q13315,P49005,O96017,Q9NTI5,O95881,P23921,P20585,P21359,P52701,Q6NTF9,Q8N3C0,P18074,P17096,Q29RF7,Q96RU2,Q9GZR2,Q13501,O15111,O60921,P09429,P28482,P29372,P53350,P46821,P09874,O95352,P49327,Q13144,Q9UER7,P57081,P14174,P51452,P18858,Q06124,P49917,P42345,Q96FW1,Q14258,Q16512,P22681,P61254,Q99570 107 +Histone h3 k36 demethylation 0.5927219001572842 1.4858439235081198 0.1373204090368545 1.0 0.3552703133956655 4 Q9UPP1 1 +Spleen development 0.5919893348454401 1.4820708450685312 0.1383214454052246 1.0 0.3570114776664493 4 Q16512,Q5JVF3 2 +Enteroendocrine cell differentiation 0.6046098077386147 1.481460303405353 0.1384839555766186 1.0 0.3571485900139493 7 Q92908,P49841,Q00534 3 +Negative regulation of type i interferon mediated signaling pathway 0.596096967325561 1.4800455438918472 0.1388610927501858 1.0 0.3575652610387949 5 Q9Y3Z3,Q9UIV1 2 +Regulation of microvillus organization 0.5912212600776365 1.4781143024633936 0.1393771864948294 1.0 0.3586024538263342 4 Q14651,Q16658,Q6IBS0 3 +Proteasomal protein catabolic process 0.2624526077434893 1.4747665615661163 0.1402753140142207 1.0 0.3603419930059312 162 P49841,Q13616,Q9Y263,Q92990,Q15008,Q9Y5K6,P49721,O14965,O14980,P17612,P49427,P25787,Q5VYK3,Q7L5D6,P20618,Q14997,Q13309,Q6NTF9,Q8N3C0,Q86UK7,O95260,O94822,Q9BW61,O60524,Q7Z6Z7,Q9UJX5,P49407,Q8IXJ6,Q9ULT8,Q13200,P28066,O75832,Q14258,P78559,O75925,Q06787,Q8TAT6,P49720,P61289,Q5T447,P53350,Q13618 42 +Protein localization to phagophore assembly site 0.5993636108961033 1.4744703399339 0.1403549978534837 1.0 0.3603419930059312 6 Q9Y4P1 1 +Dendritic cell cytokine production 0.5943243498296398 1.4709082859072382 0.1413159215351966 1.0 0.3618795951469938 5 Q9NY93,Q92499,Q9H2U1 3 +Myeloid dendritic cell cytokine production 0.5943243498296398 1.4709082859072382 0.1413159215351966 1.0 0.3618795951469938 5 Q9NY93,Q92499,Q9H2U1 3 +Positive regulation of dendritic cell cytokine production 0.5943243498296398 1.4709082859072382 0.1413159215351966 1.0 0.3618795951469938 5 Q9NY93,Q92499,Q9H2U1 3 +Positive regulation of transcription by rna polymerase ii 0.2505780091703328 1.4686908073574447 0.1419166719544096 1.0 0.3625648935298492 186 Q9UM54,O75569,Q15648,Q9UIV1,P67809,P09874,P43490,Q08209,Q92905,P10589,P51532,O75909,Q4G0J3,Q9H3P2,Q9P2D1,Q9H1B7,Q86VP6,P18615,P20248,P40763,Q86TU7,Q9NYV4,Q8NB78,Q96IU4,P78527,Q92908,P17096,O00203,Q15418,P49407,Q8IXJ6,O60244,Q13315,Q92616,Q9Y613,Q13501,Q7L2J0,O15111,Q9HCK8,Q12830,P09429,O14617,P27695,P51858,P22392,Q92974,Q99459,P63241,Q9Y2X0,Q9Y5B9,P08237,Q14684,O00401 53 +Microtubule anchoring at centrosome 0.5937097228122664 1.4677394186784394 0.1421750189347772 1.0 0.3630828602440733 5 Q9Y496,P49841 2 +Dna conformation change 0.2688518398504929 1.4651133431428052 0.1428899968336678 1.0 0.3645079931670532 139 Q9UPP1,P46063,P54132,Q12873,P38935,P26358,Q9P2D1,Q6IBW4,Q9UER7,P33992,P42695,Q9NRZ9,Q15021,P25440,Q14839,Q14997,Q8N3C0,P18074,Q92499,P17096,P16402,Q9Y620,Q9H4L7,Q8IXJ6,O14929,Q9NTJ3,Q15020,Q9BPX3,P33993,Q15047,Q96SB4,Q9HCK8,P09429,Q15003,O14646,Q92522,Q9UIF9,Q7Z5K2,Q86WJ1,P53350,Q8TEX9 41 +Regulation of attachment of spindle microtubules to kinetochore 0.6049269858849436 1.463794424826928 0.1432501262163177 1.0 0.3648938600245866 8 Q8IXJ6,P60953,Q9P258,P14635 4 +Type b pancreatic cell development 0.592814523505284 1.4631233911852668 0.1434336183784457 1.0 0.3648938600245866 5 P49841,Q00534 2 +Dendrite extension 0.5971180832942423 1.462885029243117 0.1434988411245235 1.0 0.3648938600245866 6 Q96F07,O60271,Q9BRT6,Q9Y263 4 +Fc epsilon receptor signaling pathway 0.5831522829248657 1.4606155929309912 0.1441209646482975 1.0 0.3660481910359325 3 P19174 1 +Cellular response to cadmium ion 0.595002098420634 1.451964265186675 0.1465115416722855 1.0 0.3701045907620984 6 P28482,O15111 2 +Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest 0.5855180724031542 1.4487184633951216 0.1474162221147605 1.0 0.3714422276640843 4 O96017,Q13315 2 +Mitotic g1 s transition checkpoint signaling 0.5982565268370452 1.448636069754072 0.1474392425888677 1.0 0.3714422276640843 7 O96017,P78527,Q13315 3 +Antigen processing and presentation of exogenous peptide antigen 0.5849203871478419 1.445636163392049 0.1482792779119273 1.0 0.3733474870420333 4 P50570,Q03518 2 +Digestive system development 0.6116369815762256 1.4452809740351866 0.1483789797849151 1.0 0.3733474870420333 11 Q92908,Q9HCM4,P04818,Q9HCK8 4 +Vesicle cytoskeletal trafficking 0.6300504876877866 1.4444367270108294 0.1486161659324185 1.0 0.3733474870420333 18 Q9UM54,O43795,O14617,O94832,P27695,O00203,P42858,Q9Y496,Q14204,O00401 10 +Podosome assembly 0.5974188750472187 1.4443060508141978 0.1486529044884053 1.0 0.3733474870420333 7 A1X283 1 +Basement membrane organization 0.5842884958391523 1.4423771396117768 0.149196009294263 1.0 0.3744234975755332 4 Q9NPQ8 1 +Negative regulation of telomere capping 0.5886418327615611 1.4415983536275574 0.1494157131700775 1.0 0.3747944326835895 5 Q13315 1 +Maintenance of dna repeat elements 0.5838045963975786 1.4398811749980958 0.1499010199061645 1.0 0.3756314139862553 4 P20585 1 +Positive chemotaxis 0.5957163206626219 1.4355036622773625 0.1511436254809992 1.0 0.3775699595986707 7 P14174,P09429 2 +Negative regulation of cell cycle 0.31743040645651 1.4347961033763628 0.1513452086316773 1.0 0.3779289531031942 99 Q9H6S0,O43670,Q92547,Q5TBB1,P42771,P54132,Q00535,Q13535,Q15554,P50748,Q68E01,Q00534,Q08J23,Q13564,P78527,Q99741,Q9Y3I1,Q06124,Q969U7,P42574,Q96RU2,P14635,Q5JVF3,Q13315,O96017,O60921,Q14674,Q99459,P61254,Q9H900,Q7Z7L1,Q7Z5K2,P53350,O95373,O00410 35 +Chromosome segregation 0.2668426868956181 1.430505430207467 0.1525720084207886 1.0 0.3804105440961244 140 Q93008,Q6P1K2,Q9BV86,P42695,Q69YH5,Q15021,P50748,Q14204,P18074,Q29RF7,Q8WUX9,Q8IXJ6,Q9H4L7,P19784,P14635,Q9NTJ3,O76071,Q13315,Q9BPX3,Q96SB4,Q9NTI5,Q14674,Q9BTE3,Q7Z5K2 24 +Establishment of epithelial cell polarity 0.6085067734449439 1.4289864750896888 0.1530081207989095 1.0 0.3810614144991913 11 P60953,Q9P1Y5,Q92614,Q8TEW0,Q7Z460 5 +Dna synthesis involved in dna repair 0.6081729374669069 1.4272483878407132 0.1535083115783519 1.0 0.3814342749644743 11 Q07864,P28340 2 +Ribosome disassembly 0.5890360250190214 1.4211550778337698 0.1552716809586163 1.0 0.3843533270127993 6 Q9ULC4 1 +Trna wobble uridine modification 0.588436863007206 1.418059658089557 0.1561733479918265 1.0 0.3851253634390587 6 Q2VPK5,O95163 2 +Trna wobble base modification 0.588436863007206 1.418059658089557 0.1561733479918265 1.0 0.3851253634390587 6 Q2VPK5,O95163 2 +Female meiotic nuclear division 0.6094946652339921 1.4178421266092414 0.1562368619604437 1.0 0.3851365453385041 12 O14965,Q15003,O95067,Q13315,P53350,Q6IBW4 6 +Carbohydrate phosphorylation 0.5916742266995172 1.414598288705834 0.1571863108460607 1.0 0.3871633207128333 7 Q13572,Q9UJ70,P51570,Q9Y223,P08237 5 +Protein kinase a signaling 0.591510324593563 1.41375040135828 0.1574352010672111 1.0 0.3873376966197201 7 O00170,P17612,P14174 3 +Hydrogen sulfide biosynthetic process 0.5678901820352047 1.4067911864277514 0.159489316804962 1.0 0.3907937105952728 2 P32929 1 +Hydrogen sulfide metabolic process 0.5678901820352047 1.4067911864277514 0.159489316804962 1.0 0.3907937105952728 2 P32929 1 +Modulation of excitatory postsynaptic potential 0.576933020936944 1.404418611632732 0.1601942319020735 1.0 0.3920795855774137 4 Q9UQB8,Q15334 2 +Engulfment of apoptotic cell 0.5672933452700638 1.4037101504338845 0.1604051786172862 1.0 0.3923018038842308 2 P84095 1 +Sphingolipid mediated signaling pathway 0.567293345270062 1.4037101504338751 0.1604051786172888 1.0 0.3923018038842308 2 P15311 1 +Glandular epithelial cell differentiation 0.5966961357174562 1.4025401373955255 0.1607540135330278 1.0 0.3929396378389063 9 Q92908,P49841,P49327,Q00534 4 +Epithelial cell morphogenesis 0.5889962180546633 1.4007428514835347 0.1612909835813485 1.0 0.3937308870228807 7 Q9HCM4,Q13464 2 +Endothelial cell morphogenesis 0.5710447761194098 1.3981581581612643 0.1620655784936631 1.0 0.3949650561699686 3 Q9Y696,Q9NWH9 2 +Response to lipoteichoic acid 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.3949650561699686 2 Q16539 1 +Positive regulation of leukocyte adhesion to vascular endothelial cell 0.56609967173977 1.397547325317477 0.1622490456857963 1.0 0.3949650561699686 2 P61586 1 +Regulation of leukocyte adhesion to vascular endothelial cell 0.56609967173977 1.397547325317477 0.1622490456857963 1.0 0.3949650561699686 2 P61586 1 +Positive regulation of chemokine production 0.5835143460094274 1.392621048665817 0.1637344145271568 1.0 0.3974232341336152 6 P09429 1 +Positive regulation of neurotransmitter transport 0.5696579405337591 1.3909972607703611 0.1642262573967208 1.0 0.398116157669301 3 Q15042 1 +Negative regulation of translational initiation 0.586957485050944 1.3901926003638796 0.1644703998488643 1.0 0.3984935511147313 7 Q6PKG0,P40429 2 +Regulation of cell projection organization 0.2672796519424428 1.3883508278037473 0.1650302418291305 1.0 0.3992765761927462 120 P49841,P46109,Q08209,P10589,Q00535,Q9Y2A7,Q7L576,Q8NCA5,Q9P258,Q9UPN3,Q14999,P35241,P42858,P61586,Q8WUW1,Q9Y3I1,Q9NT62,Q9HCE1,Q9H4M9,Q8TC07,P42345,P50570,Q9NZQ3,Q7KZI7,O14976,Q9UQB8,Q14155,Q16512,P27695,Q06787,Q13555,P60953,Q9P265,P46821,Q15334,O00401 36 +Positive regulation of receptor internalization 0.5737218801229949 1.3878361238118155 0.1651869521280913 1.0 0.3995077027394208 4 P49407 1 +Glandular epithelial cell development 0.5863326663983767 1.386958868400754 0.165454305414423 1.0 0.4000061511870354 7 P49327,P49841,Q00534 3 +Vesicle tethering to golgi 0.5729568320031184 1.3838845356884448 0.1663938126456767 1.0 0.4021286441807066 4 Q9HAS0,Q9BZH6 2 +Establishment or maintenance of monopolar cell polarity 0.6026839234019367 1.382295221710574 0.1668810725566474 1.0 0.4030478073683323 12 Q8NI35,P60953,Q9P1Y5,Q92538,P46821 5 +Response to hyperoxia 0.571435828474967 1.3760274515988389 0.1688131344574224 1.0 0.4063799108241568 4 O95352 1 +Negative regulation of response to cytokine stimulus 0.5879304118599171 1.3757615200431357 0.1688954783918759 1.0 0.4063799108241568 8 Q14166,Q9Y3Z3,Q9UIV1,Q01804 4 +Schwann cell development 0.5915176647868455 1.3756620905288657 0.1689262738173678 1.0 0.4063799108241568 9 P31751,P21359,Q8IXJ6,Q8TEW0,Q00535 5 +Regulation of ryanodine sensitive calcium release channel activity 0.575834526725781 1.37545639255839 0.1689899962056744 1.0 0.4063799108241568 5 P62942 1 +Motor neuron axon guidance 0.5756687847523951 1.3745998604346537 0.1692555319131672 1.0 0.406465851170769 5 O75592 1 +Columnar cuboidal epithelial cell development 0.5905204479300834 1.3704853006560134 0.1705354608417759 1.0 0.4084289931787005 9 P49327,P49841,P04818,Q00534 4 +Cell morphogenesis involved in differentiation 0.2657850673110086 1.3668943474745865 0.171658424009075 1.0 0.4096964578871565 129 P00492,P49841,Q14185,Q93008,P46109,Q08209,Q00535,Q7L576,Q9P258,Q9HCM4,Q15058,Q9UPN3,Q14999,P83731,P61586,P78527,Q06124,P42574,P50570,Q8TEW0,Q96N67,Q7KZI7,Q9Y696,O60678,Q9UQB8,Q14155,Q13418,Q16512,P78559,O75592,Q13464,P35579,P60953,Q15334,Q9P265,P46821,Q9BTW9,Q9BPU6,Q13618,Q66K74,O00401 41 +Microtubule depolymerization 0.6078969532147603 1.3649653797212689 0.1722639314679321 1.0 0.4106913006519157 15 P78559,Q14008,Q8WWK9,Q15058,P29372,Q9P1Y5,Q92974,O15344,Q7Z460,P46821,Q66K74,Q99661 12 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.5779466275381615 1.363834696901448 0.1726195974207356 1.0 0.4113890405683955 6 P15531,P17812,P27708 3 +Kinetochore assembly 0.5724763498562174 1.3580997386370306 0.1744320381471473 1.0 0.4137435131183639 5 P50748 1 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.5880860760254256 1.3578470470671224 0.1745122228240467 1.0 0.4137435131183639 9 P62081,P61254,P14174,P63241 4 +Face development 0.5880625097954545 1.3577246960616502 0.1745510574169553 1.0 0.4137435131183639 9 Q15042,P28482,Q9P2D1 3 +Xmp metabolic process 0.5806810589000664 1.357702999454057 0.1745579446617293 1.0 0.4137435131183639 7 P31939,Q06203,P12268,P22102,O15067 5 +Protein localization to microtubule 0.5879398948116579 1.3570881030863111 0.1747532181471247 1.0 0.4140560647680423 9 P78559,P29372,O60610,O15344,Q96Q89 5 +Mitotic intra s dna damage checkpoint signaling 0.5763700684605966 1.355681589810842 0.1752004995160549 1.0 0.4147894020147232 6 O96017,O60921,Q14676 3 +Histone deubiquitination 0.594343482132686 1.3552145364682282 0.1753492146174142 1.0 0.4147894020147232 11 Q9Y6J9,Q9UPT9,Q9Y4A5 3 +Organelle localization 0.2482022578791641 1.3551168608216888 0.1753803275593646 1.0 0.4147894020147232 179 Q9UM54,O43795,Q15398,Q99816,O75153,Q92905,O43933,Q00535,Q13190,Q9NVU7,Q8NCA5,Q96D46,Q99661,Q14203,Q9UBF2,O14980,P62841,P42858,Q9Y496,Q9UH99,Q14204,Q9Y678,Q9Y6B6,Q9NZ32,Q9BUK6,O94832,P42345,O00203,P50570,Q8WUX9,O00429,Q8TEW0,Q96N67,Q7KZI7,P14635,Q13315,O60271,Q9Y613,O14617,P27695,Q9BW19,Q6PJG6,P22681,P35579,P60953,Q14674,Q99996,Q7Z460,Q92538,P53350,P46821,Q15334,O00401,Q13618,Q66K74,O00743 56 +Negative regulation of dna replication 0.5908437736390698 1.3542053963815333 0.1756708578584127 1.0 0.4153261049295565 10 Q29RF7,P54132,Q13535,Q7Z5K2,P31949,Q7Z7L1 6 +Uronic acid metabolic process 0.5574455386451727 1.352840929031778 0.1761064540496963 1.0 0.4160546834097385 2 P14550 1 +Nadh regeneration 0.5832448456970857 1.3514722711711586 0.1765441965555236 1.0 0.4166366474548499 8 P85037,P17858 2 +Translesion synthesis 0.5783768085638419 1.3457725321579292 0.1783758863965718 1.0 0.4194571427736235 7 P28340 1 +Positive regulation of muscle hypertrophy 0.5818045911462264 1.344005420484446 0.1789466340894103 1.0 0.4204254673313697 8 O75116,Q13464,P09874 3 +Nucleotide salvage 0.5771361338275678 1.3393484601539356 0.1804572595992422 1.0 0.422320704184644 7 P00492,Q01433 2 +Negative regulation of cation channel activity 0.5728719387410607 1.3375890499426248 0.1810304359116856 1.0 0.4232469554254591 6 P28161,Q12955,Q06787,P62942 4 +Regulation of skeletal muscle contraction 0.5591044776119461 1.3364727217819434 0.1813948107246814 1.0 0.4237953896358389 3 P28161,P78417 2 +Embryonic digestive tract development 0.5541629364368752 1.3358738946179345 0.1815904949216653 1.0 0.4239492069497586 2 Q6KC79 1 +Double strand break repair via break induced replication 0.5762277973310541 1.334645081430368 0.1819925358281389 1.0 0.4244794181893573 7 P33993,P33991,P33992 3 +Positive regulation of cellular component organization 0.2307218183912717 1.3343852890143713 0.1820776187363537 1.0 0.4244794181893573 252 P17655,P49841,Q15398,O75116,A5YKK6,Q08209,P30419,P31751,Q00535,Q8TBX8,Q13535,Q9Y2A7,P26358,Q6DN90,Q9P2R3,Q7L576,Q8NCA5,Q96HR8,Q14203,Q9HCM4,Q86VP6,O14965,Q9UPN3,Q15021,Q14999,P49427,Q15554,P51452,P42858,P22059,Q14204,P23381,Q8WUW1,Q9Y3I1,Q9H4M9,P49917,P42345,Q9UJX5,P50570,P49407,O00429,Q9Y295,Q8IXJ6,Q7KZI7,Q9NZQ3,Q9NTJ3,Q13315,Q9Y613,Q9UQB8,Q9BPX3,Q15047,Q14155,Q16512,Q14008,Q15003,P27695,Q13464,Q06787,Q04637,P28482,P60953,P22681,Q9C0E8,Q14674,Q15042,Q99996,P63241,Q7Z460,P46821,Q15334,O00401,Q13618,Q99816 73 +Cytoskeleton organization 0.2199913947792469 1.3306778490615094 0.1832950346381698 1.0 0.4262523419470261 349 Q9UM54,Q15398,O15357,O75116,O43670,Q00535,Q12873,P57737,Q86Y56,Q8NI35,Q9UPN3,P42858,Q9UH99,P53985,Q5VZL5,Q8WUW1,P49407,Q9Y295,Q7KZI7,P47755,Q9Y613,P78559,Q13464,P60953,Q14674,Q92974,Q99996,P46940,Q9UHB6,Q9BTW9,P17655,P49841,Q9BSJ2,Q14203,Q9HCM4,P35241,Q13045,Q9Y496,Q14204,Q9H2G2,Q9H8V3,Q9P1Y5,Q8TEW0,P14635,O43237,Q9BPX3,Q14155,O96017,O75592,P63167,P35580,Q9BW19,O00401,Q13618,O43795,P31146,Q13526,P21359,Q9Y2A7,Q6DN90,Q7L576,Q9NVU7,Q9BV86,Q99661,Q15058,Q14999,Q9BUF5,Q13885,O60610,P61586,P04350,Q96P70,Q15257,Q8WUX9,Q92614,Q96N67,Q9NZQ3,Q9UQB8,O95067,P28482,P29372,Q7Z460,P53350,P46821,Q15334,Q66K74,Q9UL63,Q9Y5K6,O14965,O14980,Q86TU7,Q96F07,O94832,P42345,Q00610,Q96CW5,Q9BT25,Q16512,Q14008,P35579 100 +Histone serine phosphorylation 0.5669730427147677 1.329648842955493 0.1836339973434868 1.0 0.4265848461945817 5 Q99986 1 +Negative regulation of protein localization to cell periphery 0.5751662735886341 1.3291484085613894 0.1837990120848869 1.0 0.4266646103499152 7 O75608,Q00610,Q9HD26,Q96CW1,Q9ULT8 5 +Utp biosynthetic process 0.5618069075477116 1.3262664257326844 0.1847514636324385 1.0 0.4287231903055521 4 P15531,P27708 2 +Regulation of microtubule nucleation 0.5739933334974295 1.323074744717103 0.1858105224758655 1.0 0.4308423283639493 7 Q16512,Q14008,Q14155,Q14203 4 +Pentose metabolic process 0.5610630038817568 1.3224210080771346 0.1860279971205616 1.0 0.4308423283639493 4 Q9UKK9,P11413,P52209 3 +Caveolin mediated endocytosis 0.5610517809783984 1.3223629935243568 0.1860473055591827 1.0 0.4308423283639493 4 P28482 1 +Nervous system process 0.261974597053504 1.3220568367806833 0.1861492253689616 1.0 0.4308423283639493 107 Q9UM54,O75569,Q3SYG4,Q99504,O75116,Q13614,P21359,Q9P2D1,P42858,Q9NPQ8,Q9BPW8,Q96P11,Q00169,P42345,P42574,Q8TEW0,Q9UQB8,Q9HCK8,P78559,O75592,P28482,Q15042,P04035,Q15334 24 +Cd4 positive alpha beta t cell activation 0.5737716577250298 1.3219268698682494 0.1861925039269625 1.0 0.4308423283639493 7 Q9UDY8,P09429,P42345 3 +Positive regulation of cell cycle 0.3283571709442416 1.3209953456348924 0.1865029161450107 1.0 0.4314077373102798 97 Q15648,Q9UPT9,Q15398,P23921,O75116,O75909,Q96DE0,Q9P258,P78362,O14965,Q15058,P51452,P35241,P08243,Q14204,P61586,P62244,Q99741,Q06124,Q9H8V3,P30307,Q96QE3,Q9UJX5,Q8IXJ6,Q96Q89,Q16513,P14635,Q5JVF3,P11802,O94966,Q7L2J0,O75832,O96017,P27695,Q04637,P60953,Q14674,Q13618,Q9H6S0 39 +Fructose 6 phosphate metabolic process 0.5734375430256833 1.3201967666975922 0.1867693312173974 1.0 0.431871010215866 7 P08237,P17858 2 +Leukocyte homeostasis 0.5988991390945864 1.3176639012663651 0.187616183902858 1.0 0.4331063884495925 15 Q16512,P09429,O95067,P14174,P42574,P49327,P62753,Q9UPY5,Q9HCL2 9 +Response to uv b 0.5505819158460077 1.317360413972009 0.1877178434292568 1.0 0.4331063884495925 2 Q04206 1 +Constitutive heterochromatin assembly 0.5641109621142797 1.31485044243456 0.1885601708360762 1.0 0.4341671070379329 5 Q8IXJ6,Q9NRZ9,A6NHR9 3 +De novo amp biosynthetic process 0.5706315082559629 1.3056667824161232 0.1916658989044806 1.0 0.4397916939308484 7 O15067 1 +Negative regulation of protein tyrosine kinase activity 0.5620776395062699 1.304336838680653 0.1921187601388059 1.0 0.4397916939308484 5 Q86XI2,P22681,Q99816 3 +Negative regulation of cellular component organization 0.2440762426782169 1.3037441251491857 0.1923208392109612 1.0 0.4397916939308484 182 P49841,Q9UPP1,P31146,P09874,O75116,O43670,Q8IZH2,Q08209,Q13614,P10589,P40429,Q00535,Q9P258,Q15058,Q15554,P50748,P35241,Q13045,Q9UBB9,P61586,P04350,Q969U7,Q96QK1,Q8WWK9,Q7Z6Z7,Q9NZJ4,P50570,Q9P1Y5,Q8IXJ6,P14635,Q5JVF3,P47755,O14976,Q13315,Q9BPX3,P33993,Q14155,O75832,P46821,P63167,P09429,Q13464,P29372,P60953,Q14674,Q92974,Q15334,Q9H900,Q7Z460,Q9P265,Q9UHB6,Q7Z5K2,P53350,Q9BTW9,O00401 55 +Regulation of tissue remodeling 0.56963705204376 1.3005175193001954 0.1934236557241959 1.0 0.4418844928660614 7 O75116,Q13464,P21359 3 +Protein localization to microtubule end 0.5472993136377103 1.3003872891797508 0.1934682641813276 1.0 0.4418844928660614 2 Q15555 1 +Regulation of cellular response to stress 0.2531187782736842 1.2999653367292003 0.1936128498307263 1.0 0.4420601081799451 165 P00374,P36507,P49841,P67809,P09874,Q99504,O75116,Q5TBB1,Q7Z4V5,Q92905,P49327,O95071,Q13535,Q9Y4A5,P14174,P51452,Q96L91,Q9UBB9,Q00534,Q99873,P78527,Q9Y3I1,Q96QE3,P42345,Q13315,Q96FW1,O75832,P47897,O96017,P09429,Q06787,P28482,Q04637,P29372,P60953,Q92974,P61254,O95881 38 +Regulation of mitotic recombination 0.5564550317928606 1.2986000030187423 0.1940812369476687 1.0 0.4425106415042866 4 P18074 1 +Cytoplasmic sequestering of nf kappab 0.5561953307327888 1.2972574468149292 0.1945426205941405 1.0 0.443208126290644 4 O60826,O75832 2 +Cytoplasmic sequestering of transcription factor 0.5650477710125638 1.2971174874241018 0.1945907654020331 1.0 0.443208126290644 6 O60826,O00221,O75832 3 +Dna dependent dna replication maintenance of fidelity 0.5859713951746367 1.295056207761316 0.195300840313735 1.0 0.4445153319096165 12 Q7Z7L1,Q13535,Q07864 3 +Sulfur amino acid biosynthetic process 0.5644553967336702 1.2940534258906256 0.1956469673540546 1.0 0.4450506588735696 6 Q13126 1 +Negative regulation of developmental process 0.2599151810263841 1.2939799414803637 0.1956723494067409 1.0 0.4450506588735696 105 Q15648,P67809,O75116,P21359,Q00535,P26358,Q9P258,P14174,P26196,P40763,Q9NYV4,Q9UBS4,Q00534,Q99873,Q9Y3I1,Q06124,Q7Z6Z7,Q8IXJ6,O60271,P09429,Q13464,P28482,Q9P265,Q6W2J9 24 +Protein localization to lysosome 0.5886330331621341 1.2931551723677157 0.1959573962810443 1.0 0.4452551498473033 13 O14617,P20645,Q7Z3T8,O75116,Q9P0V3 5 +Regulation of chromosome organization 0.2593714579398259 1.2892006815421926 0.1973283281617355 1.0 0.4472798090712381 104 Q15398,P09874,O43670,Q8IZH2,Q13535,P26358,Q96HR8,Q15021,Q15554,P50748,Q99741,Q969U7,P49917,Q9UJX5,P14635,Q5JVF3,Q9NTJ3,Q13315,Q9BPX3,P33993,Q15047,Q15003,P28482,Q14674,Q9H900,Q7Z5K2,P53350,Q13618 28 +Regulation of alpha beta t cell activation 0.5848442505437943 1.2891746212359143 0.1973373859011082 1.0 0.4472798090712381 12 Q9UDY8,P09429,O14617 3 +Negative regulation of actin nucleation 0.5485103739649624 1.2817070302061178 0.1999454378582297 1.0 0.452249293111964 3 P31146 1 +Scf dependent proteasomal ubiquitin dependent protein catabolic process 0.5686098654708601 1.2756014823217272 0.2020964298497771 1.0 0.456156477581503 8 Q15058,Q13616,Q13309,Q13619,Q93034,Q13620,Q13617 7 +Peptidyl serine modification 0.5176699639772883 1.2750217159930906 0.2023015557543694 1.0 0.456156477581503 70 P36507,P49841,P68400,P09874,O75116,P31751,Q00535,Q13535,Q92600,Q9BV86,O14965,P78362,P17612,P14174,P78527,P42345,Q15418,Q96N67,Q7KZI7,P19784,Q16513,Q13315,O15111,Q13418,O96017,Q16512,Q13464,Q04637,P28482,Q99996,Q99986,Q7Z460,P53350 33 +Regulation of golgi organization 0.5752161296506693 1.272945193632531 0.2030374906583403 1.0 0.4567639078183553 10 P28482,P50570,Q9P1Y5,Q99996,Q13190 5 +Negative regulation of golgi to plasma membrane protein transport 0.5464793691710852 1.2712075213401623 0.2036548315247619 1.0 0.4570860437384727 3 Q9HD26 1 +Amino sugar metabolic process 0.5711999306231214 1.2701834844847657 0.2040192791822208 1.0 0.4573784345729808 9 Q9Y223,Q06210,Q9UJ70 3 +Regulation of non motile cilium assembly 0.5594033547602587 1.26792433365492 0.204824973286926 1.0 0.4588360465055324 6 P27695 1 +Negative regulation of lymphocyte differentiation 0.5546364561663285 1.2658638930972737 0.2055618153034348 1.0 0.4600132467208463 5 Q9Y3I1 1 +Monoubiquitinated protein deubiquitination 0.5732058719082843 1.2624975604494233 0.2067698035762879 1.0 0.4609694838232012 10 Q9UPT9,Q9Y4A5 2 +Positive regulation of actin nucleation 0.5533706225485948 1.2593203299247664 0.2079146530044673 1.0 0.462898971741961 5 O00401,Q9Y2A7,Q8WUW1 3 +Positive regulation of arp2 3 complex mediated actin nucleation 0.5533706225485948 1.2593203299247664 0.2079146530044673 1.0 0.462898971741961 5 O00401,Q9Y2A7,Q8WUW1 3 +Positive regulation of alpha beta t cell activation 0.5689536072493481 1.2585274092206034 0.2082010810142636 1.0 0.4630962889435455 9 Q9UDY8,O14617 2 +Regulation of protein modification by small protein conjugation or removal 0.3752062516316214 1.2579323374565248 0.2084162275718402 1.0 0.4632259925269287 91 Q9UBT2,Q9UHD1,Q9Y263,Q13526,Q13330,Q92990,O95071,Q00535,Q9UER7,Q9NVI1,P15880,P98170,P62081,P62841,Q01804,P61927,Q13309,P46777,Q7Z6Z7,Q13404,Q05086,P60866,P49407,O60678,Q15020,Q9UDY8,P31689,Q13501,P62942,Q96FW1,O75832,O75925,O75592,Q96GX5,P53350,Q13618 36 +Positive regulation of cell population proliferation 0.259428101350784 1.2572925338346002 0.2086477265423918 1.0 0.4633226574483722 134 Q15648,Q9UIV1,P68400,P31146,P43490,Q5TBB1,P46109,P31751,P21359,P62701,P26358,Q8NCA5,Q9HCL2,Q9ULC4,P78362,Q15058,P14174,P15531,P46087,P20248,P40763,P62244,Q00534,Q99873,Q8WUW1,Q92908,P49917,Q96QE3,Q96Q89,P14635,P62753,O76071,P11802,Q9NR09,Q13418,Q16512,P22392,P09429,P28482,P60953,Q7Z5K2,Q9Y3Y2,Q13618 43 +Regulation of exit from mitosis 0.5568890088868257 1.2549228708599138 0.2095067605593419 1.0 0.4647007970287033 6 P50748 1 +Positive regulation of cation channel activity 0.5606535346065216 1.2540114285859585 0.20983785147709 1.0 0.4651192023575688 7 P42858 1 +Protein localization to ciliary membrane 0.542687350309815 1.2516060987892808 0.2107134311831493 1.0 0.4665848442271838 3 P36405 1 +Granulocyte differentiation 0.5598991797560522 1.250107588374908 0.2112602481398799 1.0 0.4676370916452259 7 P49327 1 +Regulation of cyclin dependent protein kinase activity 0.6051214202199184 1.248604024934551 0.2118099394855623 1.0 0.4686949863912986 25 P30307,O95067,P42574,O75832,P42771,P20248,P54132,O75909,P14635,O00410,P53350,Q9UII4,O95373,Q99741,Q9Y3I1 15 +Dna recombination 0.2570419930941002 1.2473949622238465 0.2122527128438216 1.0 0.4694383567304786 104 P09874,Q7Z4V5,P46063,P35244,P20585,P38935,Q9Y3Z3,Q96FZ2,Q9Y4A5,P33992,P52701,Q96L91,Q68E01,P18858,P78527,P18074,P49917,Q96QE3,P16402,Q9Y620,Q9H4L7,Q13315,P33993,O60921,P09429,P27695 26 +Positive regulation of organelle organization 0.2518792809503863 1.2470980507747342 0.2123615475929301 1.0 0.4694383567304786 162 P49841,Q15398,O75116,A5YKK6,P30419,P31751,Q00535,Q8TBX8,Q13535,Q9Y2A7,P26358,Q7L576,Q96HR8,Q14203,O14965,Q15021,Q15554,P42858,P22059,Q14204,P61586,Q8WUW1,Q9Y3I1,P49917,P42345,Q9UJX5,O00429,Q9Y295,Q8IXJ6,Q9NTJ3,Q13315,Q9Y613,Q9UQB8,Q9BPX3,Q15047,Q16512,Q14008,Q15003,P27695,P28482,P60953,Q9C0E8,Q14674,Q15042,Q99996,Q7Z460,P46821,O00401,Q13618 49 +Protein demethylation 0.5699460947910793 1.2455607191600215 0.2129257108704361 1.0 0.4699137323846183 10 P29375,Q8NB78,Q7LBC6,Q9UPP1 4 +Muscle organ morphogenesis 0.5548748533022009 1.2445096852663424 0.2133120370218868 1.0 0.4699137323846183 6 Q9P2D1,P62942 2 +Cardiac muscle tissue morphogenesis 0.5548748533022009 1.2445096852663424 0.2133120370218868 1.0 0.4699137323846183 6 Q9P2D1,P62942 2 +Ventricular cardiac muscle tissue morphogenesis 0.5548748533022009 1.2445096852663424 0.2133120370218868 1.0 0.4699137323846183 6 Q9P2D1,P62942 2 +Membrane invagination 0.5727338669995317 1.2426740228301645 0.2139879802364208 1.0 0.471119862084905 11 P35579,P60953,P61586,Q14185 4 +Negative regulation of gliogenesis 0.554349727240368 1.2417950947706993 0.2143121730252302 1.0 0.4712857794102703 6 Q8IXJ6 1 +Trna transcription 0.5538579395243115 1.239252970438622 0.2152518293687373 1.0 0.4728692225818215 6 Q12789 1 +Endocrine pancreas development 0.5615749920706434 1.2391513217962813 0.2152894638186455 1.0 0.4728692225818215 8 Q92908,P49841,Q00534 3 +Peptidyl threonine modification 0.6079024405595463 1.236160046922368 0.2163990783931715 1.0 0.4745083888204869 34 Q16512,P49841,P68400,Q13464,P42345,Q04637,O75116,P28482,P27708,Q8TEW0,Q8IXJ6,Q7KZI7,Q00535,P19784,Q99986,P53350,P67870,P78527 18 +Positive regulation of rna binding 0.552444081825605 1.2319452537495652 0.2179695352732005 1.0 0.4773108871006034 6 Q06787,Q04637 2 +Chromatin organization 0.2428298745452181 1.2316375489754374 0.2180845079398605 1.0 0.4774025601231275 179 P41567,Q9UPT9,Q9UPP1,Q99504,O75607,P51532,Q12873,P26358,Q9P2D1,Q9Y4A5,Q9UER7,O43709,P25440,Q96L91,Q14839,Q14997,Q8NB78,P29375,P17096,Q8IXJ6,Q9H4L7,Q15020,Q96SB4,Q9HCK8,Q16512,O14646,Q9Y6J9,Q66K74,Q6W2J9,Q86WJ1,Q8TEX9,Q7LBC6,Q14527,Q9UKK9 34 +Regulation of bicellular tight junction assembly 0.5516738127712486 1.2279644956655038 0.2194602963264733 1.0 0.4788319182089209 6 O75116,Q13464 2 +Positive regulation of microtubule nucleation 0.5509796593124039 1.2243774149749491 0.2208098851960742 1.0 0.4807897800368005 6 Q16512,Q14008,Q14203 3 +Regulation of inclusion body assembly 0.5622450931537946 1.2237346197953582 0.2210523552524379 1.0 0.4811572932661399 9 Q9NZJ4 1 +Rna catabolic process 0.2578134940911035 1.2230759029273155 0.2213010291134924 1.0 0.4815380606834741 133 Q9HCE1,P27695,Q5TAX3,Q14147,P67809,Q86TB9,O75116,Q8IZH2,Q86W50,Q96C86,A5YKK6,Q99575,Q9Y2L1,Q13315,Q9Y2V2,Q96DE0,Q6P6C2,Q15477 18 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5719881903067832 1.2221421027053576 0.2216538938492505 1.0 0.4821452121371105 12 A5YKK6,P67809 2 +Regulation of type b pancreatic cell development 0.5367008686136745 1.220670451649275 0.2222108197852854 1.0 0.4830348379487064 3 P49841 1 +Reproduction 0.2289086396279934 1.2182573322814214 0.2231261988031552 1.0 0.4844740014846994 240 Q15648,P17655,Q8IY37,Q93008,Q9BSJ2,Q13144,Q4G0J3,Q9P2D1,Q6IBW4,Q9H1B7,Q92600,P42695,P52701,O14965,O95394,Q15021,P17612,Q5TAX3,Q14999,P25440,Q14997,P20248,P49770,P40763,Q9UH99,Q8NB78,Q96RD7,P47914,P78527,Q14353,Q92908,Q06124,P30307,P42345,P42574,O00203,P50570,Q8NHU6,Q9Y620,Q8IXJ6,P19784,O95248,P62753,Q9NTJ3,Q13315,Q9ULT8,Q96CW5,Q96SB4,Q9NR09,O60921,O75592,Q15003,O95067,P28482,P22681,Q00796,P35579,Q14674,P53350,Q6P6C2,Q9H6S0 61 +Rna interference 0.565704139609584 1.2061190732788067 0.2277715815789416 1.0 0.4916854306480955 11 Q9HAV4 1 +Response to zinc ion 0.5429312909376373 1.2053828923956256 0.2280555226712004 1.0 0.4918890341800449 5 O75592 1 +Positive regulation of phosphatase activity 0.5472783413241367 1.205256179445434 0.2281044206151405 1.0 0.4918890341800449 6 Q15257,P42345 2 +Positive regulation of ubiquitin protein ligase activity 0.5383601925600736 1.205093495642751 0.2281672104948477 1.0 0.4918890341800449 4 P53350 1 +Multicellular organismal response to stress 0.5506399641523336 1.2022185006771082 0.2292788832239294 1.0 0.4933084373813045 7 P17655,Q08209,Q04637,P42345 4 +Schwann cell differentiation 0.5612805200142712 1.2005750525201964 0.2299160831347793 1.0 0.4943536459894991 10 P31751,P21359,Q8IXJ6,Q8TEW0,Q00535 5 +Phosphatidylinositol phosphate biosynthetic process 0.5643300189097551 1.1989790294233296 0.2305360998697749 1.0 0.4950347688752484 11 P42356,Q01968,O00443,Q13315 4 +Establishment of sister chromatid cohesion 0.5370618644927496 1.1983902392491206 0.2307651305814819 1.0 0.4953636761002883 4 Q7Z5K2 1 +Long chain fatty acid transport 0.5703782059463343 1.1978112403595491 0.2309905102784104 1.0 0.4956845324081565 13 O43772,P31751,P07814 3 +Imp metabolic process 0.5669009238770498 1.1956547424415576 0.2318313193892098 1.0 0.4968357451957795 12 P00492,O15067,Q01433,P31939 4 +Regulation of cell substrate junction organization 0.5872597780708515 1.1953669099015118 0.2319437082055706 1.0 0.4969135218446117 20 Q9H2G2,Q9HCM4,P63167,Q9UPN3,Q13464,O75116,P51452,Q9P1Y5,Q7Z460,Q6DN90,Q9P258 11 +Dense core granule transport 0.5264100268576455 1.1924039674465392 0.2331028853901717 1.0 0.4970233017033929 2 P33176 1 +Anterograde neuronal dense core vesicle transport 0.5264100268576455 1.1924039674465392 0.2331028853901717 1.0 0.4970233017033929 2 P33176 1 +Hair follicle maturation 0.5444959620055171 1.1908892945534322 0.2336970477549624 1.0 0.4970819940846596 6 Q5C9Z4,P18074,P21359 3 +Regulation of xenophagy 0.5300345132115211 1.1862439542121792 0.2355259727286265 1.0 0.4999819526395216 3 Q96EP0 1 +Glycosyl compound biosynthetic process 0.5513180384077083 1.1860655945839362 0.2355963963662799 1.0 0.4999819526395216 8 Q13126 1 +Protein autoprocessing 0.5390529447039716 1.1853626481993826 0.2358740932823915 1.0 0.5004086514405511 5 P09874,P55212 2 +Antigen processing and presentation of exogenous antigen 0.54719182821723 1.184401853153205 0.2362540269975555 1.0 0.5010518987638964 7 O00203,P50570,O14617,Q03518 4 +Protein k48 linked deubiquitination 0.5672660482191636 1.1815889515385103 0.2373688395448308 1.0 0.5026000396328616 13 Q70CQ2,Q93008,Q01804,Q96FW1,Q6GQQ9 5 +Phosphatidylinositol 3 kinase signaling 0.5671810073815302 1.1811458461118836 0.2375447899048968 1.0 0.5028095552930231 13 Q8IXJ6,O00443,P22681,P21359 4 +N acetylneuraminate metabolic process 0.5335139039440321 1.18007889609319 0.2379688373246438 1.0 0.5032177810006231 4 Q9UJ70 1 +Establishment of centrosome localization 0.5421350658348086 1.1787042643983994 0.238515956989509 1.0 0.5039625504350302 6 Q9Y613 1 +Microtubule anchoring at microtubule organizing center 0.542101931913543 1.1785332930177013 0.2385840676479977 1.0 0.5039625504350302 6 Q14203,Q9Y496,P49841,Q8TD16 4 +Amp biosynthetic process 0.563115840627776 1.1759664993689771 0.2396082633327481 1.0 0.5057019908089351 12 P00492,O15067,P11908,P31939 4 +Positive regulation of histone phosphorylation 0.5323436052146606 1.1740412864025516 0.2403784889678348 1.0 0.5068361423829388 4 Q13315 1 +Megakaryocyte development 0.5272117777487253 1.1716767558252086 0.2413268586506289 1.0 0.5075604484039455 3 Q06124 1 +Regulation of synaptic transmission glutamatergic 0.5314921779631216 1.1696495663912865 0.2421420217293375 1.0 0.5075604484039455 4 Q15042 1 +Secretory granule localization 0.5265671641791122 1.1683511203533632 0.2426651628436449 1.0 0.5075604484039455 3 P33176,O60763 2 +Columnar cuboidal epithelial cell differentiation 0.5669654419091206 1.164766430716851 0.2441135506058329 1.0 0.5092848196345333 14 Q92908,Q15382,P49841,P49327,Q00534,P04818,P46821 7 +Purine nucleoside monophosphate biosynthetic process 0.5722104880204029 1.1638375803159773 0.2444898393455747 1.0 0.5097441414197329 16 P00492,P07741,Q01433,O15067,P31939,P49915,P12268,P20839,P11908 9 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.5469263040091977 1.1633669875433472 0.2446806376040409 1.0 0.5099791138060604 8 P14174,Q9NY93,Q92499,Q9H2U1 4 +Positive regulation of synaptic transmission 0.5741102415754484 1.1607158597400384 0.2457574699844764 1.0 0.5114073546840763 17 P27695,Q06787,P28482,Q15042,Q13501,P21359,Q00535,Q15334 8 +Astrocyte differentiation 0.5532474904580099 1.1589414417750792 0.2464800550740977 1.0 0.5122580393487773 10 Q06124,P28482,P21359,Q13144,Q00534 5 +Actin filament severing 0.5417818416514686 1.1564733805229104 0.2474875816908346 1.0 0.5140247800385337 7 P60981,P60983,P35579,Q13045,Q9BPX3 5 +Golgi to vacuole transport 0.5334017410620704 1.1562160932723011 0.2475927787389726 1.0 0.5140261121678714 5 Q9P2R3,O14617 2 +Embryonic pattern specification 0.5375048716196282 1.154824003134281 0.2481625055554741 1.0 0.5146081807803259 6 Q9HCM4 1 +Embryonic axis specification 0.5375048716196282 1.154824003134281 0.2481625055554741 1.0 0.5146081807803259 6 Q9HCM4 1 +Regulation of lymphocyte differentiation 0.5727273332098913 1.153452135567821 0.248724852843662 1.0 0.5155344937908661 17 P09429,O14617,O00203,Q9UDY8,O43290,P78527,Q9Y3I1 7 +Head morphogenesis 0.5328248615502162 1.1532427474853428 0.248810762210935 1.0 0.5155344937908661 5 Q15042 1 +Regulation of establishment or maintenance of cell polarity 0.5483305469528541 1.151696930934972 0.2494456338759776 1.0 0.5161216695849601 9 Q96Q89,O75116,Q15334 3 +Proteasome assembly 0.5408109342663376 1.1514648851716471 0.2495410334355798 1.0 0.5161555110339996 7 Q969U7,Q5VYK3 2 +Positive regulation of mitochondrial depolarization 0.5231629253226545 1.1507951467836266 0.249816521875426 1.0 0.5165617124276541 3 P09874 1 +Negative regulation of gluconeogenesis 0.5222264562281622 1.1459678763880483 0.2518084440336827 1.0 0.5183648794763211 3 Q13043 1 +Mrna modification 0.5633563308130399 1.1459486040620723 0.2518164186910376 1.0 0.5183648794763211 14 Q96FX7,Q8N1G2,Q86W50,Q69YN4,Q9UJA5 5 +Xenophagy 0.5266882280641461 1.1448848340969453 0.252256867126859 1.0 0.5183648794763211 4 Q96EP0 1 +Golgi localization 0.5304238836622701 1.1408720298119217 0.2539231804872339 1.0 0.5191353689986342 5 Q9Y678 1 +Regulation of cell matrix adhesion 0.585148919640099 1.1340030788862017 0.2567932565173367 1.0 0.5225934315271356 26 Q9H2G2,Q9HCM4,P63167,P49841,Q9UPN3,Q13464,O75116,P51452,Q9P1Y5,P42771,P21359,Q7Z460,Q00534,Q9P258 14 +Central nervous system projection neuron axonogenesis 0.5245479469490736 1.133860282673144 0.256853159521067 1.0 0.5225934315271356 4 O75592 1 +Deoxyribose phosphate catabolic process 0.5370109390345257 1.1318746395414645 0.2576871420787971 1.0 0.5238782807517265 7 Q96DE0,Q9Y3Z3 2 +Circadian regulation of gene expression 0.575012713559352 1.130448534886881 0.2582872727347556 1.0 0.5247715902171606 20 O75592,Q7Z6Z7,P43490,P62136,Q9BQG0,P29375,O14744,Q06210,Q9Y5V3 9 +Response to axon injury 0.5573263582852966 1.1298710927931326 0.2585305462081835 1.0 0.525102477990494 13 P00374 1 +Tyrosine phosphorylation of stat protein 0.5282037557913521 1.129439820696902 0.2587123425625746 1.0 0.5253083323798545 5 Q9UIV1 1 +Negative regulation of phosphoprotein phosphatase activity 0.5474170549701932 1.128778339929542 0.2589913520827105 1.0 0.5254309420476143 10 P49841,Q13464,Q15257,O75116,P62942 5 +Regulation of dendrite extension 0.5188772934957356 1.1287123502276395 0.2590191976647165 1.0 0.5254309420476143 3 Q9Y263 1 +Regulation of oligodendrocyte differentiation 0.5398638198670861 1.126917080442382 0.2597775410179139 1.0 0.5266523883411917 8 O14744,P21359,P42345 3 +Fear response 0.5182317943986754 1.1253882618820676 0.2604245429543175 1.0 0.5277298377635902 3 Q04637 1 +Non membrane bounded organelle assembly 0.2490505392976092 1.1245217462392634 0.2607917504005441 1.0 0.5280527535242026 152 Q9UIV1,Q15398,P46782,Q8IY37,A5YKK6,A1X283,O14965,P50748,P62841,P83731,P26196,Q02878,Q9NUL7,Q14204,Q9Y520,P27635,Q96F86,P78527,P62750,Q86TB9,Q8WUX9,Q7Z478,Q96CW5,Q9BT25,Q9BPX3,O96017,O95067,P62266,P39023,Q7Z460,P53350 31 +Synaptic transmission glutamatergic 0.5351315107262414 1.12219337605001 0.2617802284274548 1.0 0.5292612282544538 7 Q15042,P21359 2 +Olfactory lobe development 0.5222214172600481 1.1218832654515936 0.2619120768112362 1.0 0.5292612282544538 4 Q9P2D1 1 +Positive regulation of b cell proliferation 0.5266893595414894 1.1216456452620285 0.2620131358065274 1.0 0.5292612282544538 5 P14174 1 +Demethylation 0.5708568183295345 1.119506337742445 0.2629241886361821 1.0 0.5307248691790633 19 P27695,Q9UPP1,Q93008,Q01804,P29375,Q7LBC6,Q6P6C2 7 +Positive regulation of phosphoprotein phosphatase activity 0.5258073629343569 1.1171078213159749 0.2639482267392419 1.0 0.5324627496469724 5 Q15257 1 +Rrna modification 0.5604990620379952 1.116474939849468 0.2642188913093386 1.0 0.5328441507875173 15 O43709,Q86W50,P46087,Q8IY81,Q96P11,Q96HR8 6 +Wound healing spreading of epidermal cells 0.5203915978761187 1.11246876407544 0.2659366531169396 1.0 0.5344158569272883 4 Q7Z460 1 +Regulation of wound healing spreading of epidermal cells 0.5203915978761187 1.11246876407544 0.2659366531169396 1.0 0.5344158569272883 4 Q7Z460 1 +Negative regulation of low density lipoprotein particle clearance 0.5108922709638823 1.1123671403073658 0.2659803269546228 1.0 0.5344158569272883 2 Q92945 1 +Alditol biosynthetic process 0.5152238805970234 1.1099062371768946 0.2670394325190801 1.0 0.5355551272572461 3 Q16822,P17174 2 +Genitalia development 0.5236692286072531 1.1061122711224585 0.2686779280384697 1.0 0.537685219151458 5 Q9P2D1 1 +Amyloid fibril formation 0.5278761193242886 1.1052537037575587 0.2690496723804383 1.0 0.5382642036287568 6 Q93008 1 +Negative regulation of protein import into nucleus 0.5140746326257646 1.1039944654032456 0.2695955385386721 1.0 0.5391910770773443 3 P21359 1 +Histone mrna metabolic process 0.5486654763445602 1.1010007292108084 0.2708963397900716 1.0 0.5411297335054046 12 Q8IZH2,Q5TAX3 2 +Telomere capping 0.551191625514193 1.0980374835685036 0.2721881219180426 1.0 0.5428797911193703 13 Q9UBB9,P78527,Q13315 3 +Phosphorylation of rna polymerase ii c terminal domain 0.5303146803962062 1.0974074882577711 0.2724633014419217 1.0 0.5431737840309083 7 O75909 1 +Regulation of nervous system process 0.5478664002873554 1.096866366023855 0.2726998134842129 1.0 0.5432366632251099 12 Q06787,O75116,Q13614,Q8TEW0,Q9UQB8,Q15334 6 +Mitochondrion localization 0.5591087704502896 1.0953301404133609 0.273372027497222 1.0 0.5442437010844084 16 Q9BUK6,P27695,O75153,O00429,Q7KZI7,P46821,Q66K74,Q9NZ32 8 +Positive regulation of erythrocyte differentiation 0.5473127185321036 1.094002440606401 0.2739539078072086 1.0 0.5452359091682635 12 Q15648,P40763,P78527,Q99873 4 +Formation of translation preinitiation complex 0.5366943510372238 1.0916596758604102 0.2749827155270177 1.0 0.5469500860162734 9 Q9ULC4,Q7Z478,P40429 3 +Protection from non homologous end joining at telomere 0.5152089624031696 1.0858327633747369 0.2775529882560308 1.0 0.5503886781250323 4 Q9UBB9 1 +Negative regulation of ubiquitin protein ligase activity 0.5355180335542421 1.0856041407175103 0.2776541670539942 1.0 0.5503886781250323 9 P62081,P46777,P62841,P60866 4 +Positive regulation of signal transduction by p53 class mediator 0.5485736245185617 1.084476262358337 0.2781536862990106 1.0 0.5508572687518031 13 P62081,P62841,P60866,P61254,Q13535,Q13315 6 +Smooth muscle cell apoptotic process 0.5315798347691454 1.08426574590159 0.2782469883639411 1.0 0.5508572687518031 8 P26358 1 +Negative regulation of cell cycle g1 s phase transition 0.5485112533583122 1.0841533672614978 0.2782968039222355 1.0 0.5508572687518031 13 Q7Z7L1,P78527,Q13315,Q9Y3I1 4 +Rrna 5 end processing 0.5141177599673917 1.0802304865836188 0.2800395556633903 1.0 0.5531333488654213 4 P78316,O75691 2 +Gmp biosynthetic process 0.5477533258320468 1.0802302964074235 0.2800396403291092 1.0 0.5531333488654213 13 P00492,P07741,P31939,P49915,P12268,P20839,O15067 7 +Positive regulation of signaling 0.2193841028830712 1.0744207021870489 0.2826341679984123 1.0 0.5562390346683643 262 O75569,Q15648,Q70CQ2,P49841,P68400,P36507,Q96EP0,Q9Y3E0,O75116,P09874,P51532,P21359,O95071,Q00535,P49327,Q13535,Q9P2J5,Q92600,Q9Y5V3,Q9UPN3,P18615,P62081,P14174,P62841,P42858,P61927,P20248,P22059,Q13309,P40763,Q9BY44,Q96F07,P67870,Q99873,Q92499,Q92908,Q06124,Q9H8V3,P60866,P49407,O00429,Q5JVF3,Q13315,O60271,Q9UDY8,O14744,Q9UQB8,Q13501,P62942,O15111,Q14258,Q16512,O60826,P09429,P27695,Q13464,Q06787,P28482,P29372,P60953,P30046,P22681,P40818,Q15042,P61254,P63241,P46940,P08237,Q15334 69 +Regulation of intracellular signal transduction 0.2167845210860703 1.0726590434295526 0.2834241229004866 1.0 0.5572898291298336 295 O75116,Q13535,Q12923,Q9Y6D5,Q9NRZ9,P42858,P20248,Q6XZF7,P46777,Q99873,Q92499,Q96QE3,P49407,O60271,O75832,P47897,O60826,Q13464,P60953,Q92974,P46940,Q14152,O75569,P36507,P49841,Q5TBB1,Q92905,Q9P2J5,P18615,P35241,P46087,Q99956,P61927,Q9H8V3,O00429,P14635,Q13315,Q9UDY8,P31689,Q9P0V3,O14744,Q13418,O96017,P63167,Q92538,O95881,Q9Y3E0,P21359,P49427,P62081,P62841,Q96P70,Q13501,P62942,O15111,P09429,P28482,P29372,P30046,P04035,Q96EP0,P09874,O00170,P49327,Q9Y5K6,Q9Y5V3,O14965,P14174,P51452,Q6GQQ9,Q06124,P42345,P50570,P60866,Q5JVF3,Q14258,Q16512,P22681,P61254,P63241,Q86X10 81 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.5358975996367716 1.0693612666899666 0.2849069135169535 1.0 0.5595314722603628 10 P14174,P61254 2 +Amp salvage 0.5161982111363306 1.0677543785549577 0.2856313220494964 1.0 0.5607854879684941 5 P00492 1 +Kinetochore organization 0.5312799835605243 1.06381153431387 0.2874140850918136 1.0 0.5636078004953583 9 Q9NTJ3,P50748 2 +Response to nicotine 0.5274455867882433 1.063030130489265 0.2877682875956999 1.0 0.5639636608643219 8 P42574,P28482 2 +Rna methylation 0.5767904557561123 1.061057873839878 0.2886636008038235 1.0 0.5653789181910519 34 Q96FX7,Q86W50,Q4G0J3,Q69YN4,O60294,Q9UBP6,P57081,Q9UET6,O43709,P46087,Q8TEA1,Q08J23,Q96P11,Q8N1G2,Q8IY81,Q7Z2T5,Q9UJA5,Q7L2J0,Q7Z4G4,Q8WVM0 20 +Erythrocyte development 0.5221750958598645 1.0556239197094175 0.2911400682750047 1.0 0.5695460293097007 7 P62753,P18074 2 +Mitotic nuclear division 0.2492652509312645 1.0527027277240324 0.2924772581149608 1.0 0.5711353156371692 128 Q15398,O43670,Q13526,Q6IBW4,Q6NUK4,Q9GZZ1,Q99661,P42695,O14965,Q69YH5,Q15058,Q15021,Q14999,P50748,P83731,P61586,Q99741,Q969U7,P30307,Q9UJX5,Q29RF7,Q8WUX9,Q9Y295,Q8IXJ6,Q96Q89,P14635,Q5JVF3,Q9NTJ3,Q13315,O14744,Q9BPX3,O96017,Q15003,Q9BW19,Q9NTI5,P60953,Q14674,Q9H6H4,Q9H900,Q7Z460,P53350,Q13618 42 +Layer formation in cerebral cortex 0.5029270194056009 1.0467701634969493 0.2952055944703562 1.0 0.5746107260728556 3 Q00535 1 +Positive regulation of membrane depolarization 0.5074867653698203 1.0462370100757732 0.2954516194311087 1.0 0.5746107260728556 4 P63244,P09874 2 +Actin filament based transport 0.5241551475558344 1.0461561464956703 0.295488946118323 1.0 0.5746107260728556 8 Q9UM54,Q9UH99,O00401,O94832 4 +Fatty acid transmembrane transport 0.5202607045146129 1.0458175196281363 0.2956452908262577 1.0 0.574743599016214 7 O43772 1 +Negative regulation of cell matrix adhesion 0.5198435124035192 1.043681620923339 0.2966327158894892 1.0 0.5761486123612031 7 Q9P258,P21359,P42771 3 +Regulation of biomineralization 0.5268108256646012 1.0408754345947149 0.2979333641395729 1.0 0.5783308168345457 9 O75116,Q6W2J9,P20248 3 +Non canonical wnt signaling pathway 0.5062911593268389 1.040117772265115 0.2982851877240082 1.0 0.5788416867274216 4 P60953 1 +Golgi to endosome transport 0.5149794704118851 1.0391167692059142 0.2987504328648955 1.0 0.5795722895447915 6 Q7Z3U7,Q92538 2 +Positive regulation of transferase activity 0.2467900347683637 1.0336694854285788 0.3012907031244394 1.0 0.583806614659522 111 P36507,Q13526,O75909,Q00535,Q9UNI6,Q9UER7,Q96HR8,Q9Y5V3,P15880,Q15058,Q96JP5,P14174,P20248,P61586,Q9H8V3,P42345,Q08AM6,Q7KZI7,Q15185,P14635,Q92616,Q9UDY8,O75832,Q16512,Q05639,P28482,P60953,Q96GX5,P46940,Q99570,P53350,Q15334 32 +Histone h2a ubiquitination 0.5214059939602511 1.0320782188517863 0.3020354765344435 1.0 0.5849026280456453 8 O95071,Q6W2J9 2 +Regulation of ubiquitin protein ligase activity 0.5410809066043001 1.0303924218610216 0.3028258291813952 1.0 0.5857383485054831 14 P62081,P62841,P60866,P61927,O00429,P46777,P53350 7 +Positive regulation of hemopoiesis 0.5482169010134326 1.0254080247127932 0.3051707033343809 1.0 0.5892266980406586 17 P09429,O14617,O00203,Q9UDY8,O43290,P78527 6 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.497314829097955 1.0180585500787045 0.308650132067878 1.0 0.5941160449850083 3 Q03518 1 +Phospholipid dephosphorylation 0.5104006778257371 1.015726298362518 0.3097597411295174 1.0 0.5957970867675254 6 Q01968,Q13614,O15357 3 +Phosphatidylinositol dephosphorylation 0.5104006778257371 1.015726298362518 0.3097597411295174 1.0 0.5957970867675254 6 Q01968,Q13614,O15357 3 +Nuclear transcribed mrna poly a tail shortening 0.521702726675628 1.014723257700184 0.3102377643460812 1.0 0.5965408130682892 9 A5YKK6,Q5TAX3 2 +Positive regulation of osteoblast differentiation 0.5098961739691633 1.013152428514451 0.3109873589843441 1.0 0.5976302101729745 6 Q96AC1,Q13418,P20248,O00299 4 +Synaptic vesicle transport 0.5243277318621117 1.009991405278538 0.3124994078103034 1.0 0.6001826861768473 10 O00203,P50570,O14617 3 +Mitotic chromosome condensation 0.5300315885068905 1.0049929378811968 0.3149002504366123 1.0 0.6039056197800524 12 Q15003,Q15021,Q9NTJ3,P53350,Q9BPX3,P42695 6 +Negative regulation of microtubule polymerization or depolymerization 0.5358751397301601 1.0035743965096795 0.3155838007230902 1.0 0.6048612323809155 14 P04350,Q8WWK9,P29372,Q9P1Y5,Q92974,Q7Z460,P46821,Q9BTW9,Q14155 9 +Pyrimidine ribonucleotide biosynthetic process 0.5152942241141274 1.000853539189456 0.3168976211534622 1.0 0.6068450047308235 8 P15531,P17812,P27708 3 +Neuroepithelial cell differentiation 0.4983882223900404 0.9997574974708364 0.3174278791179605 1.0 0.6075041180071168 4 P07437,P46821 2 +Ruffle organization 0.5349216261107098 0.998671664787995 0.3179537712812523 1.0 0.6081541085139361 14 O15357,P42345,P35241,Q9UHB6,Q7L576,Q9P258,Q8NCA5 7 +Negative regulation of protein localization to membrane 0.5147708480292916 0.9981846332355904 0.3181898365131717 1.0 0.608427417988583 8 O75608,Q00610,Q9HD26,Q96CW1,Q9ULT8 5 +Positive regulation of ubiquitin protein transferase activity 0.5179517381366321 0.9955664576636688 0.3194608389985185 1.0 0.6094301135437704 9 P15880,Q96GX5,P53350 3 +Establishment of epithelial cell apical basal polarity 0.5102929189558669 0.9949095488076104 0.3197802582752933 1.0 0.6098612986383368 7 P60953,Q9P1Y5 2 +Positive regulation of glucose transmembrane transport 0.5017631053720915 0.9939869991904724 0.3202291968717263 1.0 0.610539169510182 5 P31751 1 +Eyelid development in camera type eye 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.6172399716448527 2 Q13547 1 +Small gtpase mediated signal transduction 0.278283286611718 0.9852526741874296 0.3244999728417732 1.0 0.6172399716448527 100 Q14185,O75116,P46109,P42771,P21359,Q9Y2A7,P26358,Q6DN90,Q7L576,Q9Y6D5,Q9Y5K6,Q15058,P35241,P20248,Q6XZF7,Q8WUW1,Q9H8V3,Q96T51,P50570,P49407,Q96N67,Q96RU2,Q13501,Q15047,P63167,Q13464,P22681,P60953,P40818,Q92974,Q92538,Q86X10,Q13618 33 +Detection of cell density 0.4908023116393911 0.9848410048034416 0.3247021755237136 1.0 0.617444730975495 3 Q16512 1 +T cell lineage commitment 0.4998475175661179 0.984239444652305 0.3249977957029657 1.0 0.617826959516846 5 P40763,P78527,P42345 3 +Negative regulation of cell substrate adhesion 0.5190026216445905 0.982794696865626 0.3257084924150359 1.0 0.6182426095324584 10 P63167,Q9BTW9,P21359,P42771,Q9P258 5 +Chromosome movement towards spindle pole 0.4939184893595533 0.9770058582187024 0.3285662521464128 1.0 0.622616838803272 4 Q15398 1 +Negative regulation of dna templated transcription elongation 0.5140391393392391 0.9756310471803352 0.3292473332249657 1.0 0.6235106314231413 9 Q8IXH7,Q9H3P2,Q4G0J3,P18615 4 +Amyloid beta formation 0.5272457280875792 0.9746752436392966 0.3297213767810343 1.0 0.6237197538760585 13 O75116,P27695 2 +Axis specification 0.5173562527486132 0.974404938887404 0.3298555181834737 1.0 0.6237927986498938 10 Q6W2J9,Q9HCM4,Q8NHU6 3 +Limbic system development 0.5470375248137215 0.9729894993914164 0.3305585209769579 1.0 0.6249412686680762 21 Q9H0D6,O75569,P49841,Q15058,P27695,P42574,P46109,Q15042,P21359,Q13144,Q00535,Q00534 12 +Protein neddylation 0.501924374454948 0.9725796716158832 0.3307622499880676 1.0 0.6251454391959714 6 Q8TBC4,P61081,Q13564,P46777 4 +Cardiac ventricle morphogenesis 0.5055590359997517 0.9708334974564734 0.3316311988496778 1.0 0.6266064029190961 7 Q9P2D1,P62942 2 +Polysaccharide catabolic process 0.5052025112793161 0.9690231789374468 0.3325336244367298 1.0 0.6277665705613894 7 P08237,P11216,P06737,P35573 4 +Cellular polysaccharide catabolic process 0.5052025112793161 0.9690231789374468 0.3325336244367298 1.0 0.6277665705613894 7 P08237,P11216,P06737,P35573 4 +Negative regulation of axon extension 0.48727512252647 0.9669010830392152 0.3335934851782429 1.0 0.6295853925473776 3 Q00535 1 +Regulation of amyloid precursor protein catabolic process 0.5337837696152098 0.9641606616146348 0.3349653834856785 1.0 0.630683134920704 16 P42574,O75116,Q96P70,P27695 4 +Focal adhesion assembly 0.5449382773474468 0.962055894017583 0.3360215278794118 1.0 0.6314303818856286 21 Q9H2G2,Q9HCM4,P63167,Q9UPN3,Q13464,P51452,O75116,Q9P1Y5,Q7Z460,Q9P258,Q14155 11 +Negative regulation of blood vessel endothelial cell migration 0.4953105445867231 0.9611982577941912 0.3364524922224934 1.0 0.6320583355042814 5 P67870,P09429 2 +Regulation of supramolecular fiber organization 0.2936872380712936 0.9596391133205175 0.3372368765777029 1.0 0.6331675687327201 98 P31146,O75116,Q9Y2A7,Q7L576,Q14203,P35241,Q13045,P61586,Q96F07,Q8WUW1,P04350,P42345,Q9P1Y5,Q9Y295,P47755,Q9Y613,Q9UQB8,Q9BPX3,Q14155,Q16512,P78559,P63167,Q14008,Q13464,P29372,P60953,Q92974,Q99996,Q7Z460,Q9UHB6,P46821,Q9BTW9,O00401,Q66K74 34 +Regulation of ruffle assembly 0.5070129622492106 0.9587263494639642 0.3376966207051328 1.0 0.633484324390841 8 Q7L576,P35241,Q8NCA5,Q9P258 4 +Translational termination 0.5030613056939008 0.9581598913111466 0.3379821387543584 1.0 0.6338378420637452 7 Q8N543,P61221,P63241 3 +Cellular response to nitrogen compound 0.2426914400307277 0.957663398997884 0.3382325186352362 1.0 0.634125278980216 140 P17655,P49841,P07741,P09874,P43490,O75116,Q8IZH2,Q9BY42,P46109,P31751,P54132,Q00535,Q8TBX8,P26358,Q9P2J5,Q7L576,Q9UER7,P17612,P07814,O60610,P20248,P40763,P78527,Q99741,O14654,Q06124,P55212,P42574,P42345,P50570,O00443,Q8IXJ6,P11802,O14744,Q9P0V3,Q9UQB8,P27695,Q13464,Q06787,P28482,Q99707,Q6PKG0,Q92974,Q99996,P46821,Q9Y5X3,O00410 47 +Negative regulation of lymphocyte apoptotic process 0.4985298369976484 0.9553637913078298 0.3393937582159103 1.0 0.635937228450472 6 Q9HCL2 1 +Negative regulation of leukocyte apoptotic process 0.4985298369976484 0.9553637913078298 0.3393937582159103 1.0 0.635937228450472 6 Q9HCL2 1 +Water soluble vitamin biosynthetic process 0.4938758087259186 0.9539259440592062 0.3401211298502113 1.0 0.6369346079500661 5 O00764 1 +Inositol lipid mediated signaling 0.5367025225751596 0.9532319199391128 0.34047257686895 1.0 0.637409956122203 18 P22681,O00443,P21359,Q8IXJ6,P42356 5 +Glial cell development 0.5409526279455565 0.9519535831690118 0.3411205228170848 1.0 0.6382570240674968 20 P31751,P21359,Q8TEW0,P49770,Q13144,Q00535,Q8IXJ6,Q00534,Q96P11,P18074 10 +Positive regulation of cell matrix adhesion 0.5159903041708853 0.9500497876518614 0.3420869552075292 1.0 0.639689175195473 11 Q9HCM4,Q13464,Q00534 3 +Regulation of release of sequestered calcium ion into cytosol 0.5188444001716457 0.94785542313166 0.3432030609334142 1.0 0.6406849593754131 12 P27695,P17612,P31146,O60610,P42858,Q9P2D1,P62942 7 +Regulation of calcium ion transport into cytosol 0.5188444001716457 0.94785542313166 0.3432030609334142 1.0 0.6406849593754131 12 P27695,P17612,P31146,O60610,P42858,Q9P2D1,P62942 7 +Protein localization to cilium 0.5237091712368347 0.9412644352401248 0.3465693634544307 1.0 0.645124841321959 14 Q9H4M9,P49841,Q3SYG4,Q9Y5K8 4 +Negative regulation of phosphatase activity 0.5134840660423993 0.9373260029263774 0.3485908912726723 1.0 0.6474114106969711 11 P49841,Q13464,Q15257,O75116,Q96GX5,P62942 6 +Transepithelial chloride transport 0.4765741569680549 0.9368922027818708 0.348814010402342 1.0 0.6474784920526846 2 P55011 1 +Anion homeostasis 0.4986724740809335 0.9359442788369288 0.3493018776591281 1.0 0.6479946764528711 7 P12277,Q9Y666,Q9UPY5 3 +Apical protein localization 0.4855768950782538 0.934715461517932 0.3499349565933529 1.0 0.6489847391521143 4 P18085,P35241 2 +Negative regulation of cellular amide metabolic process 0.3618217627675298 0.9341917007659551 0.3502050159834442 1.0 0.6493011795490887 89 P00374,Q9HCE1,Q9UIV1,P27695,Q5TAX3,P67809,Q86TB9,P07814,O75116,Q8IZH2,Q86W50,A5YKK6,Q6PKG0,P40429,Q9Y2L1,Q96C86 16 +Skeletal muscle tissue regeneration 0.4934986594848011 0.9299220695256268 0.3524114353203029 1.0 0.6522808029029417 6 Q7Z4V5 1 +Oogenesis 0.531304046989733 0.9254780875823324 0.3547172766765381 1.0 0.6559908854992335 18 O14965,Q5TAX3,Q8NHU6,Q8IXJ6,P62753,Q96RD7,Q13315 7 +Vitamin biosynthetic process 0.4922682034397794 0.9237143239750272 0.3556350723379575 1.0 0.6573158851873374 6 O00764 1 +Intra golgi vesicle mediated transport 0.5273515061725635 0.9178886752472764 0.3586771511279272 1.0 0.6623760737741415 17 Q9UBF2,Q14746,P53621,Q96JB2,P53618 5 +Golgi vesicle transport 0.2418534168685531 0.9172094388760244 0.3590329016455393 1.0 0.6628455888451716 126 O14579,O43795,Q7Z3U7,Q15436,P84085,P18085,P53618,O95782,Q13190,P57737,Q4J6C6,Q9P2R3,O15258,Q9Y6D5,Q9UBF2,Q14746,Q9UPN3,P55735,P42858,Q9Y296,O95070,Q9Y678,Q9Y6B6,Q96KP1,P53621,P50570,Q92614,O14976,O95486,O60493,P63244,O60826,O14617,P53992,Q7Z392,Q8TBA6,Q96JB2,O15027,Q8TAG9,Q92538,Q9UID3,Q15334,Q13618,O00743 44 +Monocyte differentiation 0.494709936089284 0.9159493676558076 0.3596934519338943 1.0 0.6638773999797428 7 P35579,Q15648,P49327,Q00534 4 +Regulation of cellular component movement 0.2365837714316066 0.9107853469230074 0.3624084846035653 1.0 0.6677560396335445 159 P31146,Q9Y263,Q14185,O75116,P46109,Q08209,Q13526,P31751,P21359,Q00535,Q6DN90,Q9P258,Q9HCM4,Q15058,Q9UPN3,P14174,P51452,P35241,O60610,O94776,P20248,P40763,Q9UH99,P31949,Q00534,P67870,Q9H2G2,P42345,Q9H9T3,P55196,O00443,Q9P1Y5,O00429,Q96N67,Q96Q89,Q16513,Q13315,O60271,Q14155,Q16512,P57076,O75592,P27695,Q13464,P63167,P09429,P28482,P30046,P42785,Q92974,Q99996,Q7Z460,O00401 53 +Rna 5 end processing 0.5176408929699838 0.9104055362653484 0.3626086791200715 1.0 0.6678840642483849 14 O75818,Q99575,O15091 3 +Supramolecular fiber organization 0.2304105618186352 0.9102654673790416 0.3626825255474384 1.0 0.6678840642483849 175 Q9UM54,O43795,P31146,O15357,O75116,O43670,Q93008,Q13526,P21359,Q9BSJ2,Q9Y2A7,P57737,Q7L576,Q9Y5K6,Q99661,Q14203,Q15058,P35241,O60610,Q13045,Q14204,P61586,Q96F07,Q8WUW1,Q9H2G2,P04350,O94832,P42345,Q96P70,Q9P1Y5,P49407,Q9Y295,Q96CW5,P47755,Q9Y613,Q9UQB8,Q9BPX3,P62942,Q14155,Q16512,P78559,P63167,Q14008,Q13464,P29372,P60953,Q92974,Q99996,Q7Z460,Q9UHB6,P46821,Q9BTW9,O00401,Q13618,Q66K74 55 +Flavin containing compound metabolic process 0.4758641637548898 0.9091485631974836 0.3632717111360231 1.0 0.6683169935866717 3 Q969G6 1 +Ribonucleoside metabolic process 0.497183743721191 0.9090438067054836 0.3633270026390023 1.0 0.6683169935866717 8 P00492,Q13126 2 +Purine ribonucleoside metabolic process 0.497183743721191 0.9090438067054836 0.3633270026390023 1.0 0.6683169935866717 8 P00492,Q13126 2 +Cellular response to thyroid hormone stimulus 0.4846449436233192 0.9073159150041772 0.3642397604428082 1.0 0.6696187037419871 5 P35241,Q15648,P48507 3 +Positive regulation of cell differentiation 0.2401664944033114 0.9037023702780907 0.3661532419373781 1.0 0.672568402208461 138 Q15648,P49841,O00299,Q14185,P09874,P46109,Q9UQ80,Q7L576,O14965,Q9UPN3,Q14999,P61160,P20248,P40763,Q86TU7,P61586,O43290,Q99873,P78527,Q9Y6C9,Q92908,P49917,Q9H8V3,P42345,O00203,P50570,Q15418,Q8IXJ6,Q5JVF3,Q8IYB5,O60271,Q9UDY8,O14744,Q9UQB8,Q14155,Q13418,O96017,P43034,Q15382,O14617,P27695,P09429,Q04637,P22392,P60953,Q92974,P46821,Q14790 48 +Inositol phosphate metabolic process 0.4955080070581323 0.9006127862278267 0.3677942338694362 1.0 0.6746338053841063 8 Q9UNW1,Q9BW91,Q13572,Q13614,Q01968,Q96PE3 6 +Response to testosterone 0.5125143989625818 0.899758679644105 0.3682486882137401 1.0 0.6749306195047672 13 O75116,Q13126 2 +Negative regulation of cell substrate junction organization 0.4785995793764513 0.8995360629702642 0.368367195837211 1.0 0.6749306195047672 4 P63167,Q9P258 2 +Uv damage excision repair 0.4785987247318344 0.8995317658424723 0.3683694836010704 1.0 0.6749306195047672 4 Q13620 1 +Alpha beta t cell activation 0.5199839158905444 0.8936787560612836 0.3714937949542056 1.0 0.6795110591179169 16 P09429,O14617,P42345,O00203,Q9UDY8 5 +Cochlea development 0.4855903358799517 0.8901313372522681 0.3733953680275648 1.0 0.6826068738017912 6 P33993,P43034,P20248 3 +Long term synaptic potentiation 0.4970567607952672 0.8897556467018674 0.373597107018329 1.0 0.6826117951609971 9 Q13501,P28482,P21359 3 +Aorta development 0.48947465221159 0.8896317177174631 0.3736636694226365 1.0 0.6826117951609971 7 Q9ULT8 1 +Neurotrophin signaling pathway 0.4970142841999804 0.8895423671475496 0.3737116642726745 1.0 0.6826117951609971 9 Q06124,P27695,P31146,P42574,Q96F07,Q7L576 6 +Activation of cysteine type endopeptidase activity 0.4718252332161224 0.8888257920530614 0.3740967120903484 1.0 0.6831240296280692 3 Q96F07 1 +Negative regulation of peptidyl tyrosine phosphorylation 0.4844849211535368 0.8845906841884797 0.3763774328950378 1.0 0.686329136220217 6 Q86XI2,P22681,Q99816 3 +Establishment of mitotic spindle localization 0.5122345510123205 0.8830546897435477 0.3772067235078347 1.0 0.6872655983555135 14 Q14203,Q14674,P42858,Q7Z460,P53350,P63172 6 +Biological adhesion 0.2273991784789226 0.8782411149108997 0.379812884054211 1.0 0.6905397065088712 178 P49841,P31146,O15357,Q14185,O75116,O00299,P46109,Q08209,P42771,Q92990,P21359,Q00535,Q9UPY5,Q9P258,Q9HCL2,Q9UL63,Q9Y5K6,Q9HCM4,Q9UPN3,P51452,P35241,P20248,Q9NPQ8,P31949,Q00534,Q96F07,O43290,Q9H2G2,Q06124,P42574,O00203,P50570,P55196,Q9P1Y5,Q8TEW0,Q16513,Q13315,Q9UDY8,Q9UQB8,Q14155,Q13418,P22392,P63167,O14617,P35580,Q13464,P09429,P35579,P60953,Q15334,Q7Z460,Q9Y223,Q9BTW9 53 +Oligodendrocyte differentiation 0.5262669330851736 0.876392952544638 0.3808164482465255 1.0 0.6905936440368351 20 P42345,P21359,P49770,Q13144,Q00535,O14744,Q96P11,P18074 8 +Cell fate determination 0.4739433175989138 0.8761712316907236 0.3809369534181746 1.0 0.6905936440368351 4 Q92908 1 +Regulation of transcription by rna polymerase iii 0.510500869233042 0.8743143999460018 0.3819470594352292 1.0 0.6920405932608342 14 P42345,P30044,Q9NY93,Q659A1,Q9UIG0,Q9H2U1,O75533,Q9BUI4,Q9BQG0,Q9HCK8 10 +B cell apoptotic process 0.4823100171341705 0.873705691709503 0.3822785505248554 1.0 0.6923952772902826 6 Q16512,P14174 2 +Polyol catabolic process 0.4862666775329612 0.8735655747958105 0.3823548805373291 1.0 0.6923952772902826 7 Q01968,Q13614 2 +Very long chain fatty acid catabolic process 0.4732756046581133 0.8728286004921886 0.382756508056733 1.0 0.6929304124231956 4 P28288,Q15067,O14975 3 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.5095996879697524 0.8697772296353279 0.384422157527543 1.0 0.6947901158745796 14 Q06124,P09429,P30046,P14174,P40763,Q9Y6D5 6 +Negative regulation of hemopoiesis 0.4965561672161698 0.8693199028856176 0.3846721796526875 1.0 0.6950496217852932 10 Q9Y3I1,Q00534,P21359 3 +Positive regulation of translational initiation 0.5029600584533886 0.8675975005879887 0.3856147152038542 1.0 0.6963672816043055 12 Q13144,Q6PKG0,Q7Z478 3 +Positive regulation of cell substrate junction organization 0.4921838597204702 0.8653441261254557 0.3868499383183206 1.0 0.6980188165843143 9 Q96AC1,Q9HCM4,Q13464,P51452,Q15555,Q6DN90 6 +Myelin assembly 0.4805620891729327 0.8649737092309857 0.3870532190183446 1.0 0.6981926851353013 6 P18074 1 +Regulation of jnk cascade 0.5022377108330384 0.8639761892040448 0.3876009708890167 1.0 0.6986018051077225 12 P09429,P98170,P51452,P60953,Q92905,P31689,P43034 7 +Deoxyribonucleoside monophosphate metabolic process 0.4880348654652877 0.8631688858652945 0.3880446179589265 1.0 0.6990394204103174 8 P04183,P04818 2 +Positive regulation of chromosome segregation 0.4878690794474067 0.862341252466054 0.3884997582881031 1.0 0.6995842241478151 8 Q8IXJ6,P14635 2 +Process utilizing autophagic mechanism 0.2337698442871402 0.8609395262306833 0.3892713506078471 1.0 0.7004524440532494 160 O14681,Q96EP0,Q9Y263,O95352,Q00535,Q9Y5K8,P42858,P40763,Q9Y296,Q9Y3I1,Q9H269,Q9NT62,Q7Z6Z7,P42345,P42574,O00443,Q8WUX9,Q00610,Q8IXJ6,Q7KZI7,P19784,Q13315,Q9P0V3,Q13501,Q05639,P09429,P27695,Q13464,Q9Y4P1,P50851,Q6PKG0,Q15042,P85037,Q99570,Q9UID3,Q8NCE2,Q66K74,Q99816 38 +Negative regulation of smoothened signaling pathway 0.4657149100235468 0.8582155513111811 0.3907734503765767 1.0 0.7027147727165042 3 P17612 1 +Cellular response to x ray 0.4791788932931033 0.8580742533962402 0.3908514631709561 1.0 0.7027147727165042 6 Q13315 1 +Synaptic vesicle localization 0.4973319962279333 0.8559812412573128 0.3920081555818158 1.0 0.7042127251579801 11 O00203,P50570,O14617 3 +Nucleobase containing small molecule biosynthetic process 0.4826771582840382 0.8556467664959414 0.3921931935923664 1.0 0.704351362529745 7 P00492,Q13126 2 +Regulation of cilium assembly 0.514923030186154 0.8547682736028417 0.3926794453479227 1.0 0.7045061283421082 17 Q9NT62,Q8TC07,P27695,P50570,P42858 5 +Spindle localization 0.5260683332650011 0.8546828857963106 0.3927267275548067 1.0 0.7045061283421082 22 Q14203,P35579,Q14674,P42858,Q14204,Q7Z460,P53350,P63172,Q15334,O00401,P43034 11 +Response to ether 0.4692593714575831 0.8527672053897707 0.3937884135885778 1.0 0.7055295331017796 4 Q6PKG0 1 +Ruffle assembly 0.4966766053571953 0.8527073474343018 0.3938216153378233 1.0 0.7055295331017796 11 O15357,P35241,Q9P258,Q7L576,Q8NCA5 5 +Response to growth factor 0.2357746802153908 0.8516565685243835 0.3944047327604634 1.0 0.706079467578254 109 Q15648,P31146,P09874,O75116,Q93008,P46109,Q13526,Q9HCM4,P49427,P51452,P35241,P20248,P40763,Q96F07,Q92908,Q9H4M9,Q06124,P42574,P50570,Q8IXJ6,O43237,Q9UQB8,P33993,P62942,Q13418,P27695,Q13464,P28482,P22681,P40818,Q9H223,P46940,P46821 33 +Regulation of rrna processing 0.4930038054377615 0.8515696860228271 0.3944529705552022 1.0 0.706079467578254 10 Q96DE0 1 +Regulation of organic acid transport 0.4961091244155916 0.8498744431756229 0.3953948957693414 1.0 0.7073777176366574 11 Q15042,P31751,P07814 3 +Nucleotide excision repair 0.522939130350837 0.8487465889181053 0.3960223160848048 1.0 0.7075936874477443 21 O60921,Q07864,P35244,P28340,P18074 5 +Regulation of amyloid beta clearance 0.4727115134466298 0.8475897029240859 0.3966665109179672 1.0 0.7084880515028245 5 P04035,Q13464 2 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.4680008130489594 0.846496762339088 0.3972756792528396 1.0 0.7088748447731482 4 P22681 1 +Glycolytic process through fructose 6 phosphate 0.4918467312535537 0.8458023355475118 0.3976630223502941 1.0 0.7092583541507781 10 Q9BRR6,Q01813,P85037,P08237,P17858 5 +Protein k63 linked ubiquitination 0.5102380267764652 0.84446167602864 0.3984114701955978 1.0 0.7098572715899738 16 O95071,Q96JP5,Q9Y263 3 +Meiosis ii cell cycle process 0.4670921128953134 0.8419743606271048 0.3998023051264676 1.0 0.7117527405877409 4 Q96GX5,O43683 2 +Locomotion 0.2119874673820687 0.8414328915388383 0.4001054655530749 1.0 0.7120983074575031 254 P31146,Q9Y263,Q14185,O75116,Q93008,P46109,Q08209,Q13526,P31751,P21359,Q00535,Q9BSJ2,O43776,Q9Y2A7,Q6DN90,Q7L576,Q9P258,Q9Y5K6,Q9HCM4,Q15058,Q9UPN3,P14174,Q13885,P35241,P83731,O60610,P51452,O94776,P20248,P40763,Q9UH99,P31949,Q9NPQ8,Q00534,P67870,Q8WUW1,Q9Y3I1,Q9H2G2,Q06124,P42345,Q9H9T3,P55196,O00443,Q9P1Y5,O00429,Q92614,Q96N67,Q7KZI7,Q96Q89,Q16513,Q13315,O60271,Q14155,Q13418,Q16512,O75592,P63167,P27695,Q13464,Q6PJG6,Q00796,P09429,P60953,P28482,P30046,P35579,Q92974,P42785,P46940,Q7Z460,Q92538,Q9UHB6,P46821,Q9BPU6,Q13618,O00401 76 +Deoxyribonucleoside triphosphate metabolic process 0.4873480368913732 0.8412358911627923 0.4002157973879525 1.0 0.7121005877229782 9 Q96DE0,P04818,Q9Y3Z3 3 +Anterior posterior axis specification 0.4833754647571202 0.8399619129618383 0.4009297417933468 1.0 0.7131765769301429 8 Q9HCM4,Q8NHU6 2 +Rna modification 0.4820880103179196 0.8393169983643213 0.4012914469282973 1.0 0.7134445489923235 65 Q2VPK5,Q96FX7,Q86W50,Q4G0J3,Q69YN4,O60294,Q96DE0,Q96HR8,Q9UBP6,P57081,Q9UET6,O43709,O95163,Q6P1R4,Q9UBS4,Q8TEA1,Q96P11,Q8N1G2,Q9H9T3,Q7Z2T5,Q9UJA5,Q7L2J0,Q7Z4G4,Q6P6C2 24 +Regulation of stem cell population maintenance 0.4709716627086473 0.8389389482507233 0.4015035701903078 1.0 0.7136141299245264 5 Q9Y6J9 1 +Inclusion body assembly 0.4931917936987615 0.8353386309993911 0.4035270723975985 1.0 0.7164306097760518 11 Q9NZJ4 1 +L ascorbic acid metabolic process 0.4656352545396577 0.8347327579955403 0.4038681932214556 1.0 0.7168413432280797 4 P78417,P48506 2 +Segmentation 0.4942141080443148 0.8239417677744306 0.4099726463868802 1.0 0.7255071492971078 12 Q9HCM4,Q8NHU6,P78527 3 +Negative regulation of nucleobase containing compound metabolic process 0.2044480120994968 0.8202042971026599 0.4120996527227603 1.0 0.7280873193397253 316 Q15648,Q9UIV1,P67809,P09874,Q8IZH2,Q86W50,Q93008,A5YKK6,P10589,P42771,P20585,O95071,P51532,Q00535,Q12873,P26358,Q4G0J3,Q9H3P2,Q96DE0,Q9UER7,Q9UPT8,Q96HR8,Q9UKL3,Q9Y5V3,Q9H1B7,P52701,O14981,P40763,Q9UBB9,Q8NB78,Q00534,P29375,P27635,Q9BQ70,Q8IWS0,Q6GQQ9,P17096,Q92908,P62854,Q8IXJ6,Q13315,Q14240,Q96FW1,Q13501,Q7L2J0,Q9HCK8,O75832,O75925,O75182,P09429,P27695,P47897,Q14147,Q06787,P62277,Q6PKG0,Q96KM6,P35251,P85037,P53350,Q9Y2X9,Q6W2J9,Q99816 63 +Regulation of cell differentiation 0.2139936592527141 0.8165983616882763 0.4141579916560995 1.0 0.7311304908122006 235 Q15648,P49841,P67809,O00299,Q14185,O75116,P46109,P09874,Q08209,P21359,Q00535,P26358,Q7L576,Q9P2D1,Q9P258,Q9GZS3,O14965,Q15058,Q9UPN3,P17612,Q14999,P26196,P20248,P40763,Q86TU7,Q9NYV4,Q9UBS4,P61586,Q00534,P63172,O43290,Q99873,P78527,Q9Y6C9,Q9Y3I1,Q92908,P49917,Q9H8V3,Q06124,P42345,O00203,P50570,Q15418,Q96N67,Q8IXJ6,Q5JVF3,O60271,Q9UDY8,O14744,Q9UQB8,Q14155,Q13418,O96017,P22392,P09429,O14617,P27695,Q13464,Q04637,P28482,P60953,Q9C0E8,Q92974,Q7Z460,Q9P265,P46821 66 +Regulation of cell population proliferation 0.2136653830291792 0.8145231233565763 0.4153453309669985 1.0 0.7326323639153163 237 O75569,Q15648,Q9UIV1,P68400,P31146,O15357,P43490,Q5TBB1,P46109,P35244,P31751,P42771,Q92990,P21359,P62701,P26358,Q9UPY5,Q8NCA5,Q9HCL2,Q9Y5V3,Q9ULC4,P78362,Q15058,P14174,P15531,P46087,P20248,P40763,P23381,P31949,P61586,P62244,Q00534,P67870,Q99873,Q8WUW1,P78527,Q92908,P17096,P49917,Q96QE3,P42574,Q8IXJ6,Q96Q89,O75691,P62753,P14635,O76071,Q13315,P11802,Q9P0V3,Q9NR09,Q13418,Q16512,O75925,P63167,P09429,P22392,P28482,Q9NTI5,P60953,Q92974,Q7Z5K2,Q9Y3Y2,Q13618,Q99816 66 +Positive regulation of neuron apoptotic process 0.4945243672794126 0.8096811578110129 0.41812345006182 1.0 0.7365379360409184 13 P78362,P49427,P42574,P60953,P21359,P61081,Q00535,Q13315 8 +Amyloid precursor protein catabolic process 0.5078701112820456 0.8067273624074178 0.4198235760842552 1.0 0.7377416447336347 18 P42574,O75116,Q96P70,P27695 4 +Dna strand elongation involved in dna replication 0.4904916817154094 0.8054946177555566 0.4205343110145247 1.0 0.7381959814314104 12 Q07864,P49916,P25205,P18858,P09884,P33991,P33993,P49005 8 +Cell matrix adhesion 0.529999565817633 0.8041217585691717 0.421326659539063 1.0 0.7393880910481273 35 Q9H2G2,Q9HCM4,P49841,Q9UPN3,Q13464,O75116,P51452,Q9P1Y5,P42771,P21359,Q00535,Q7Z460,Q00534,Q9P258,Q9UL63,Q14155,Q13418 17 +Torc1 signaling 0.4759320352226209 0.803134482848242 0.421897008797742 1.0 0.7395939509930888 8 Q6PKG0,Q13315,P42345 3 +Fatty acid transport 0.5065110759018321 0.7999408558747049 0.4237450650844523 1.0 0.7422358570282922 18 P29375,O43772,P31751,P07814 4 +Positive regulation of interferon beta production 0.4922862272189627 0.7986049423681495 0.424519520930231 1.0 0.7433929932084765 13 Q9NW08,Q9BUI4,O14802 3 +Negative regulation of histone methylation 0.4820223887602577 0.7971381132751144 0.425370823317952 1.0 0.743974885603915 10 P26358 1 +Developmental process involved in reproduction 0.2325860888405855 0.7963257958564274 0.4258426958581152 1.0 0.7445121295725547 150 Q15648,Q8IY37,Q13144,Q4G0J3,Q9P2D1,Q9H1B7,P52701,O14965,Q5TAX3,Q14999,P25440,Q14997,P20248,Q96RD7,P78527,Q14353,Q06124,P30307,P42345,P42574,O00203,P50570,Q8NHU6,Q8IXJ6,P19784,O95248,P62753,Q13315,Q9ULT8,Q96SB4,Q9NR09,P28482,P22681,Q6P6C2,Q9H6S0 35 +Aminoacyl trna metabolism involved in translational fidelity 0.481712460645357 0.7956122935778669 0.4262574188922983 1.0 0.7450377262758854 10 Q9BTE6,P26640,P41252 3 +B cell proliferation 0.4850709476263698 0.7951353400629277 0.4265347793420202 1.0 0.7453230155481381 11 Q16512,P14174,P42574,P17812,Q13315 5 +Endocytosis 0.2337825819051295 0.7928469226233599 0.4278670145147352 1.0 0.7472510309658253 116 Q9UM54,Q7Z3T8,O15357,Q14185,Q13614,Q00535,O75165,Q9P2R3,Q9UL63,Q9Y5K6,P20645,P15531,Q9H4M9,Q96T51,Q9UBC2,P50570,O94973,O00443,P49407,O00429,Q92614,Q9NZQ3,Q00610,O14976,Q9P0V3,Q06787,Q13464,P28482,P22681,P35579,P60953,Q8NC96,Q9H223,Q9Y5X3,Q15334,O00401,Q99816 37 +Regulation of toll like receptor signaling pathway 0.4737411965455785 0.7923570378801438 0.428152522454744 1.0 0.7475497250346199 8 Q01804 1 +Regulation of t cell differentiation 0.4877259965293354 0.7918444349209008 0.4284513893900439 1.0 0.7478715778446904 12 Q9UDY8,P09429,O14617,O43290 4 +Regulation of hematopoietic stem cell differentiation 0.4724429262146918 0.7859844913981037 0.4318765729272107 1.0 0.753180452762645 8 Q00534 1 +Regulation of rna polymerase ii transcription preinitiation complex assembly 0.4557392865897268 0.7858520309542707 0.4319541800300315 1.0 0.753180452762645 4 P09429 1 +Fibroblast growth factor receptor signaling pathway 0.4720744777088001 0.7841779093384137 0.4329357254111388 1.0 0.7544890010501032 8 Q06124,P46940 2 +Response to aldosterone 0.4498818639470406 0.7797816213284364 0.4355194260013892 1.0 0.7575764123039616 3 P09874 1 +Establishment of spindle orientation 0.4913191105507077 0.7787456204648953 0.4361295767104693 1.0 0.7582337955056881 14 Q14203,P42858,Q7Z460,P53350,P63172,Q15334 6 +Positive regulation of nucleobase containing compound metabolic process 0.2066445776277477 0.7746488345219542 0.4385471924628852 1.0 0.7610186465008345 427 Q9UM54,O75569,Q15648,Q9UPT9,Q9UPP1,Q9UIV1,P67809,P09874,Q99504,O75116,Q93008,Q86W50,Q7Z4V5,A5YKK6,P10589,O00170,Q6P1K2,P51532,O75909,Q13535,Q3B7T1,Q4G0J3,Q9H3P2,Q9P2D1,Q96FZ2,Q9Y4A5,Q9UER7,Q96D46,Q96HR8,Q9Y5V3,Q86VP6,Q5TAX3,O43709,Q96L91,Q01804,Q9Y2L1,Q86TU7,Q9NYV4,Q8NB78,P29375,P78527,P18074,Q9HCE1,P17096,Q86TB9,P42345,O00203,P50570,P49407,Q8IXJ6,Q5JVF3,Q13315,Q92616,Q9Y613,Q13501,Q7L2J0,O15111,Q9HCK8,O96017,Q14258,P09429,O14617,P27695,P28482,Q16512,P22392,P63241,P35251,P85037,Q9Y2X0,P08237,Q96C86,Q9Y2X9,O75155,Q99816 75 +Protein transport along microtubule 0.4573236905313659 0.7716657250235871 0.4403124359270414 1.0 0.7630679953831159 5 P78559 1 +Regulation of mitotic centrosome separation 0.4425544613548112 0.7671170987046128 0.4430118966011571 1.0 0.7667287794342846 2 P52732 1 +Biomineralization 0.4946259447372156 0.7668030856011222 0.4431986015337499 1.0 0.7668486666707437 16 Q9Y4P1,O75116,P20248,Q9UBB9,Q6W2J9,P18074 6 +Central nervous system neuron axonogenesis 0.4606089771227916 0.7664565762226192 0.4434046801814997 1.0 0.7670020030689254 6 O75592 1 +Endocrine system development 0.4912341560837474 0.7639116238388454 0.444919909998944 1.0 0.7688966465010465 15 Q92908,P49841,P28482,P46109,P21359,Q00534 6 +Regulation of keratinocyte differentiation 0.4700217694680278 0.7559690507121698 0.4496677518746681 1.0 0.7727185315109428 9 P22392,Q15648,O75116 3 +Ovulation cycle 0.4696358774301488 0.754092092764288 0.4507939250959014 1.0 0.7742462732446702 9 P42574 1 +Positive regulation of transcription elongation from rna polymerase ii promoter 0.4798484340928094 0.7532431385036046 0.4513038209552302 1.0 0.7744157339997696 12 O75909 1 +Brain morphogenesis 0.4614710744136696 0.7512499907942783 0.4525022196936139 1.0 0.775752033236886 7 Q9UID3 1 +Polysaccharide biosynthetic process 0.4885237860233382 0.7506343694400087 0.4528727308853666 1.0 0.7761834468980168 15 O43505,P49841,P31751,P62136,Q15185,Q00610,P46976,P35573,P13807 9 +Pyrimidine nucleobase biosynthetic process 0.457265696558911 0.7501873791267899 0.4531418589457765 1.0 0.7762372347628332 6 P17812,P27708 2 +Snrna transcription by rna polymerase iii 0.4389734407639387 0.7496161324315498 0.4534859318193764 1.0 0.7764192802256237 2 Q659A1 1 +Negative regulation of dephosphorylation 0.4849982001515266 0.7477751277708271 0.4545958068743505 1.0 0.7777077859286112 14 P49841,Q13464,Q15257,O75116,P46940,P62942 6 +Proteasome mediated ubiquitin dependent protein catabolic process 0.2320837351662786 0.7472340510364929 0.4549222932414354 1.0 0.7780624868691915 131 Q13616,Q9Y263,Q15008,Q9Y5K6,O14965,O14980,P49427,P25787,Q5VYK3,Q13309,Q6NTF9,Q8N3C0,O94822,O60524,Q7Z6Z7,P49407,Q8IXJ6,Q9ULT8,Q14258,P78559,O75925,P53350 22 +Cellular component morphogenesis 0.2308121519856242 0.7469414395915441 0.4550989103566569 1.0 0.7781607448622597 142 P00492,P49841,Q9BRT6,Q9Y263,Q93008,Q08209,Q13614,Q00535,Q9Y2A7,O14965,Q9UPN3,Q14999,P83731,Q13045,Q96F07,P18074,Q06124,Q9HCE1,P50570,O00429,Q8TEW0,Q96N67,Q7KZI7,Q96Q89,O60678,O60271,Q9UQB8,Q14155,Q16512,P78559,O75592,Q13464,P60953,P46940,Q7Z460,Q9P265,P46821,Q15334,Q9BPU6,Q66K74,O00401 41 +Double strand break repair 0.2697015284482473 0.745604984651922 0.4559060708948865 1.0 0.779336817524505 99 Q9NUW8,P09874,Q99504,Q7Z4V5,P46063,P35244,P54132,Q13330,O95071,Q9Y3Z3,Q96FZ2,Q9Y4A5,O00487,A6NHR9,P33992,P61160,Q96L91,Q68E01,Q9UBB9,Q15645,P78527,Q92499,Q96T76,P49917,Q9Y620,Q9H4L7,P09884,Q13315,Q96FW1,P33993,O96017,O60921,P09429,Q9BRJ7 34 +Protein autophosphorylation 0.5187657551200643 0.7435870250829046 0.457126355181088 1.0 0.7804013331588248 38 O96017,P36507,O14965,P49841,Q16512,P17612,P42345,P27708,Q99986,Q7KZI7,Q00535,P49761,Q13535,Q9NYV4,Q13315 15 +Establishment of cell polarity 0.510718964455753 0.7416478974949949 0.4583006953190733 1.0 0.7815888065901146 48 P49841,O75116,P46109,Q14203,Q8NI35,P42858,P61586,P63172,Q9P1Y5,Q92614,Q8TEW0,Q96N67,Q7KZI7,Q96Q89,Q13464,P35579,P60953,Q7Z460,Q92538,P53350,P46821,Q15334 22 +Pyrimidine nucleoside triphosphate biosynthetic process 0.4631541098903096 0.740715637973935 0.458865875540704 1.0 0.7821441313706076 8 P22392,P17812,P15531,P27708 4 +Positive regulation of focal adhesion assembly 0.4550680678321507 0.7395353192825462 0.4595820011026923 1.0 0.7823632109625797 6 Q9HCM4 1 +Positive regulation of myoblast differentiation 0.4365860937033652 0.7379968734036619 0.4605163490900459 1.0 0.7831759976849948 2 Q16539 1 +Pyridine containing compound metabolic process 0.4663060953195416 0.7379404068384157 0.4605506632634579 1.0 0.7831759976849948 9 Q13126 1 +Positive regulation of endothelial cell apoptotic process 0.4412062011750587 0.7374424635745357 0.4608533203564775 1.0 0.7834448771848466 3 P19174 1 +Cell part morphogenesis 0.2315425683212075 0.7372855269764523 0.4609487317219265 1.0 0.7834448771848466 128 P00492,P49841,Q9BRT6,Q9Y263,Q93008,Q08209,Q00535,Q9Y2A7,O14965,Q9UPN3,Q14999,P83731,Q96F07,Q06124,Q9HCE1,P50570,O00429,Q8TEW0,Q96N67,Q7KZI7,Q96Q89,O60678,O60271,Q9UQB8,Q14155,Q16512,P78559,O75592,Q13464,P60953,P46940,Q9P265,P46821,Q15334,Q9BPU6,Q66K74,O00401 37 +Amyloid beta metabolic process 0.4855159938745835 0.735964752355131 0.4617521488118612 1.0 0.7842280059866163 15 O75116,P27695 2 +Snrna transport 0.4408955223880693 0.7359357770904996 0.4617697830043705 1.0 0.7842280059866163 3 Q9H814,P62826 2 +Negative regulation of arp2 3 complex mediated actin nucleation 0.4359892569382185 0.7350982633267114 0.4622796519321688 1.0 0.7848897886419819 2 P60983 1 +Protein targeting to vacuole 0.4753657984319148 0.7314752844950398 0.4644888955824453 1.0 0.7872080166502383 12 O00203,O14617,P20645,Q7Z3T8 4 +Meiotic spindle organization 0.4568803675028769 0.7290328060598429 0.4659815952260913 1.0 0.7893280977500327 7 O14965,O95067,Q14674 3 +Ephrin receptor signaling pathway 0.4515167049367595 0.7223953502957619 0.4700514447991446 1.0 0.7943674778826124 6 Q06124,Q16512,Q14155 3 +Negative regulation of phagocytosis 0.4549150163143272 0.7195687364113824 0.4717905668580817 1.0 0.7960703880060139 7 Q9NT62,O60493,P09429 3 +Positive regulation of transcription by rna polymerase iii 0.4693096441559356 0.7183513811617097 0.4725406565517287 1.0 0.7963753698628324 11 P42345,Q9NY93,Q659A1,Q9UIG0,O75533,Q9BQG0,Q9HCK8 7 +Regulation of establishment of planar polarity 0.4460727252784759 0.7171054491294218 0.4733090337269605 1.0 0.796779579849717 5 P60953 1 +Negative regulation of protein dephosphorylation 0.4716724084544371 0.7136559165834057 0.4754399719702507 1.0 0.7995423685206636 12 P49841,Q13464,Q15257,O75116,P62942 5 +Centromere complex assembly 0.4602023445274339 0.7085483028164575 0.4786048272417935 1.0 0.8032098488534855 9 Q9NRZ9,Q15398,P50748 3 +Pinocytosis 0.4483944524161705 0.7074048172008675 0.4793149441738566 1.0 0.8041162753258458 6 Q9P2R3,P60953,P50570,Q9H223 4 +Ribonucleoprotein complex disassembly 0.4437487492898409 0.7059508034523009 0.4802187322945772 1.0 0.8050907116517558 5 Q9UBB9 1 +Regulation of cytoplasmic translation 0.4788789151188624 0.7038483489299848 0.4815272203713014 1.0 0.8062494228268202 15 P40429,P67809,P42345 3 +Regulation of calcium mediated signaling 0.4515849015537684 0.7036006343574196 0.4816815162010766 1.0 0.806301025581397 7 P49841,P42858,P42345 3 +Pancreas development 0.4694658895823745 0.7030624898924188 0.4820168069439292 1.0 0.8066554970127775 12 Q92908,P49841,Q00534 3 +Positive regulation of cytoplasmic transport 0.4424115634992082 0.6995517101679172 0.4842073088942844 1.0 0.8092842915484202 5 Q13614 1 +Positive regulation of early endosome to late endosome transport 0.4424115634992082 0.6995517101679172 0.4842073088942844 1.0 0.8092842915484202 5 Q13614 1 +Positive regulation of striated muscle cell differentiation 0.4419418446859401 0.6973072558758615 0.4856105281750076 1.0 0.8112143128633409 5 Q9UGN5,Q16539,P42345 3 +Cell activation 0.2283999819463008 0.6960976943113848 0.4863676503818301 1.0 0.8122712933486831 139 P00492,P31146,O00299,Q92990,Q9UPY5,Q96FZ2,Q6IBW4,Q9P2D1,Q9HCL2,Q9NRZ9,P52701,P14174,P51452,P17812,P40763,Q00534,O43290,P78527,Q9Y3I1,Q06124,P49917,Q96QE3,P42345,P42574,O00203,Q15418,Q92614,Q5JVF3,P62753,Q13315,Q9ULT8,Q9UDY8,O14744,P62942,Q13418,Q16512,P09429,O14617,P22681,P35579,Q92538 41 +Tissue regeneration 0.4499026237405886 0.6955675266252175 0.4866997086552687 1.0 0.8126180254458973 7 P58546,P58107,Q08209,Q7Z4V5 4 +Protein destabilization 0.4609602877195968 0.6949655495399473 0.4870768915645564 1.0 0.812735132165063 10 Q13618,P42858,P53350,P78527 4 +Histone modification 0.2244964998226505 0.6946611280709495 0.4872676940928364 1.0 0.812735132165063 162 Q9UPT9,Q9UPP1,Q99504,O95071,Q00535,Q12873,P26358,Q9H3P2,Q9Y4A5,Q9GZZ1,Q9BV86,O14965,Q96L91,Q14839,P20248,Q86TU7,Q8NB78,P29375,Q99873,Q7Z6Z7,P49407,P50747,Q8IXJ6,Q9H4L7,Q13315,Q15020,Q96FW1,Q16512,O75182,Q06787,Q9Y6J9,Q99986,Q9UIF9,Q6W2J9,Q9Y3Y2,Q7LBC6,Q6UXN9 37 +Pyrimidine ribonucleoside triphosphate metabolic process 0.449596752725232 0.6941094251762627 0.487613588259546 1.0 0.8131043747024607 7 P15531,P17812,P27708 3 +Phosphatidylinositol biosynthetic process 0.4975720415615988 0.6935797832076059 0.4879457758103078 1.0 0.8132469787164509 24 O96017,O15357,O00443,P42356,Q01968,Q08AM6,Q99570,Q13315,Q8NCE2 9 +Microtubule bundle formation 0.4737826396944321 0.6935759391361431 0.4879481872298705 1.0 0.8132469787164509 14 O43670,Q7Z460,P53350,P46821,Q66K74 5 +Negative regulation of b cell activation 0.4453275784919591 0.6927548381867407 0.4884634183442133 1.0 0.8136903371907431 6 P42574,Q13315 2 +Regulation of protein catabolic process 0.2285570435144908 0.6902023859940385 0.4900669231087575 1.0 0.8152839937191794 124 P49841,P68400,O95352,Q13526,Q92990,Q16850,Q13190,O00487,O14965,O14980,P17612,P62081,P35241,O43847,P46379,P46777,Q9BW61,Q96QK1,Q7Z6Z7,Q05086,Q8IXJ6,P14735,P19784,O43242,Q9ULT8,O60493,O94966,Q13200,P62829,P63244,Q13620,O75832,O96017,Q05639,O60826,P78559,Q06787,Q13464,O75925,O75592,P40818,Q9UNN5,P61289,P53350,P04035 45 +Microtubule organizing center localization 0.4839068516807339 0.6890803849095383 0.4907726829788188 1.0 0.81545690072562 18 O14965,Q15398,Q8TEW0,Q9UH99,O43237,Q9Y613 6 +Regulation of macrophage activation 0.4399616878907557 0.6878651467880478 0.4915377064859791 1.0 0.815911095312672 5 Q92614,Q13315 2 +Macrophage activation 0.4399616878907557 0.6878651467880478 0.4915377064859791 1.0 0.815911095312672 5 Q92614,Q13315 2 +Regulation of cartilage development 0.4442976669428412 0.6878522531483211 0.4915458267932697 1.0 0.815911095312672 6 Q06124,Q9C0E8 2 +Dna replication initiation 0.495942061907044 0.6856097930322501 0.4929592044159987 1.0 0.8176336308957256 24 O43913,P49427,P25205,Q92547,Q8WTT2,P09884,P49643,P33991,Q9UBD5,P33993,P49642,Q99741,P33992 13 +Cellular metabolic compound salvage 0.4654449785177162 0.6838631861196588 0.494061562445363 1.0 0.8192539367110768 12 Q01433,Q13126 2 +Glucan biosynthetic process 0.4618339083039148 0.6825957235353027 0.4948623371048293 1.0 0.8201652439833845 11 P49841,P31751,P62136,Q15185,P46976,P35573 6 +Establishment of tissue polarity 0.4545309700633934 0.6815053313653179 0.4955517944689305 1.0 0.8210995224263171 9 P60953,P61586,P43034 3 +Protein localization to vacuole 0.482133410401636 0.6805627375686469 0.4961482116454669 1.0 0.8216707638967535 18 O14617,P20645,Q7Z3T8,O00203,O75116,Q9P0V3 6 +Positive regulation of neuron death 0.4909388708414395 0.679484832200664 0.4968307149781774 1.0 0.8225924363102177 22 P17655,P49841,P78362,P49427,P09874,P42574,P60953,P21359,P61081,Q00535,P61586,Q13315,Q9UER7 13 +Non motile cilium assembly 0.4644186399311446 0.678984949451476 0.4971473982692231 1.0 0.8226995718950906 12 Q14203,P27695,P27816,P50570,Q9UIS9,Q15555 6 +Somitogenesis 0.4498848226706762 0.6771564339305575 0.4983067060514474 1.0 0.8244091184484297 8 Q9HCM4,P78527 2 +Erbb2 signaling pathway 0.4280597014925453 0.6743239794329857 0.500105362019603 1.0 0.826965817672324 3 Q9UNE7,Q93034 2 +Ires dependent viral translational initiation 0.4633828707639679 0.6740713577669282 0.5002659481402927 1.0 0.8270219345205344 12 Q9ULC4,Q14152,P41214 3 +Regulation of meiotic cell cycle 0.4410393817990212 0.6724007965469471 0.5013285758434776 1.0 0.8285303705237775 6 Q8IXJ6,P30307 2 +Positive regulation of lamellipodium assembly 0.4658531017821245 0.6705245399519705 0.5025234682301298 1.0 0.8290748477874552 13 P61160,P42345,P60953,P50570,Q9Y2A7,Q7L576,Q8WUW1 7 +Positive regulation of stress fiber assembly 0.4652200417994029 0.6675274155701354 0.5044353038742155 1.0 0.8305503112200271 13 Q16512,O75116,Q9Y613,P42345 4 +Nucleolar chromatin organization 0.4477019308742484 0.6668399217779619 0.5048743894873053 1.0 0.8310637164991439 8 Q8IXJ6,Q9UPP1 2 +Regulation of myelination 0.4613852081025764 0.6646219531445171 0.5062923242772217 1.0 0.8331877211517786 12 P42345,Q13614,Q8TEW0,Q8IXJ6,Q7L576,Q96P11 6 +Tight junction organization 0.4834827226174649 0.6641416868543816 0.5065996314351415 1.0 0.8333986543493778 20 Q8NI35,Q13464,P17612,O75116,P55196,Q8TEW0,Q9BTW9 7 +Negative regulation of amyloid beta clearance 0.4256699791518299 0.6630010385675966 0.5073298889212761 1.0 0.8340544246364383 3 P04035 1 +Jnk cascade 0.4808077155421184 0.6624916402069083 0.5076561906920865 1.0 0.8341546502268883 19 P09429,P51452,P46109,P60953,Q92905,Q99956,P31689,Q9UER7,P43034 9 +Female gamete generation 0.497809121760272 0.6597180572367092 0.5094347766302403 1.0 0.8351164209327717 29 O14965,Q15003,Q5TAX3,O95067,Q93008,Q8NHU6,Q8IXJ6,P62753,Q96RD7,Q13315,P53350,Q6IBW4,Q9H6S0 13 +Establishment of protein localization to vacuole 0.4635418129351847 0.6596000234647537 0.5095105392030876 1.0 0.8351164209327717 13 O00203,O14617,P20645,Q7Z3T8 4 +Positive regulation of ligase activity 0.4243459742426665 0.6567491387552833 0.5113422326802295 1.0 0.8376981383346459 3 Q13155 1 +Anterograde dendritic transport 0.4229850746268737 0.6503393400989514 0.5154730508432128 1.0 0.8421413615226869 3 P33176,Q9NUL3 2 +Ribonucleotide catabolic process 0.4475094722048545 0.6484110804575269 0.5167191055580727 1.0 0.8435439398235537 9 Q96DE0 1 +Synaptic vesicle endosomal processing 0.4268251404870909 0.6468430736956507 0.5177335117479973 1.0 0.8442374881088514 4 O14617 1 +Response to dietary excess 0.4168904804535918 0.6438011562064556 0.519704383928399 1.0 0.8461465655846928 2 Q16539 1 +Regulation of cell substrate adhesion 0.4969805385807829 0.6421797738255504 0.5207564641008577 1.0 0.846747935901046 44 P49841,Q14185,O75116,P46109,P21359,P42771,Q9P258,Q9HCM4,Q9UPN3,P51452,P20248,Q00534,Q9H2G2,P50570,Q9P1Y5,Q14155,Q13418,P63167,Q13464,P60953,Q7Z460,Q9BTW9 22 +Mirna metabolic process 0.4496207586156758 0.6414352551339211 0.5212399335611348 1.0 0.8473230684974384 10 Q9HAV4 1 +Rna splicing via endonucleolytic cleavage and ligation 0.4300213192925626 0.6409732175992631 0.5215400838575879 1.0 0.8475999869562092 5 Q9Y3I0,Q92499 2 +Positive regulation of canonical wnt signaling pathway 0.473555596953423 0.6397873842450513 0.5223108355070123 1.0 0.8477276759317695 18 Q96QK1,Q70CQ2,P98170,P40818,Q13526,O95071,Q96K76,Q13418 8 +Liver regeneration 0.449162045968191 0.6392947938835327 0.5226311746184822 1.0 0.8477276759317695 10 P19784,O14965,P62841,P04818 4 +Polarized epithelial cell differentiation 0.4455376074604552 0.63919889627595 0.5226935500465735 1.0 0.8477276759317695 9 P60953,Q9P1Y5 2 +Regulation of postsynaptic membrane potential 0.4559402479320568 0.639055178154322 0.5227870369030989 1.0 0.8477276759317695 12 P49841,Q15042,Q13614,Q00535,Q9UQB8,Q15334 6 +Chemical synaptic transmission postsynaptic 0.4559402479320568 0.639055178154322 0.5227870369030989 1.0 0.8477276759317695 12 P49841,Q15042,Q13614,Q00535,Q9UQB8,Q15334 6 +Negative regulation of gene expression 0.2017544588080669 0.638071968006562 0.5234268331646985 1.0 0.8481333975487485 284 P00374,O75569,P36507,P49841,Q9UPP1,Q9UIV1,P67809,O15357,Q9HAU5,O75116,Q8IZH2,Q86W50,A5YKK6,P40429,P26358,Q96DE0,Q9UER7,Q9Y5K6,Q9NRZ9,O14965,Q5TAX3,Q9HAV4,P07814,Q8IWR0,P14174,P26196,Q14839,Q9Y2L1,P40763,Q6PGP7,Q96F86,Q6GQQ9,Q92908,Q9HCE1,Q86TB9,P62854,P49407,Q8IXJ6,Q5JVF3,Q13315,Q15477,P09429,P27695,Q13464,Q14147,Q06787,P62277,Q04637,Q96C86,Q6PKG0,Q9UIF9,Q9Y2V2,Q9Y2X9,Q6P6C2,P04818 55 +Amino acid homeostasis 0.4198146922606139 0.6354727195542126 0.5251201535349799 1.0 0.8502441365195682 3 P29144 1 +Vesicle mediated transport 0.1982544127059897 0.6347142927959402 0.5256147701686702 1.0 0.8508340231039703 351 Q9UM54,O15357,Q14185,Q13614,Q00535,Q13190,P57737,Q9Y6D5,Q9UPN3,P42858,O95070,Q0VDF9,Q9Y6B6,Q9H269,Q96T51,O00443,P49407,O14976,O60271,O60826,O14617,P27695,Q06787,Q13464,P60953,Q8NC96,P36507,P49841,Q7Z3T8,Q9Y263,Q15436,Q92905,O75165,Q9UBF2,Q14203,Q14746,P15531,P35241,Q9BXS5,Q9NT62,Q9H4M9,Q9UBC2,O94973,O00429,O95486,Q9P0V3,Q96JB2,Q15042,Q92538,Q9UID3,Q9Y5X3,O00401,Q13618,O00743,O14579,O43795,P31146,Q9Y3E0,P84085,Q08209,P53618,Q4J6C6,Q9P2R3,Q7L576,P20645,O75436,Q9Y296,Q10567,Q92544,Q96QK1,Q96KP1,P53621,Q9BZH6,Q9NRW7,Q8WUX9,Q92614,Q9NZQ3,Q8IYB5,Q13501,O60333,P09429,P53992,Q7Z392,P28482,Q15019,O15027,Q9UGU5,Q9H223,Q8TAG9,Q7Z460,Q5VIR6,Q15334,Q2M389,Q9Y217,Q99816,Q7Z3U7,Q13432,P31751,P18085,O95782,O60343,Q9UL63,Q9Y5K6,Q9Y678,O94832,O00203,P50570,Q00610,Q16512,P22681,P35579,Q99570 112 +Nuclear transcribed mrna catabolic process exonucleolytic 0.4611900267338231 0.6340300318796139 0.5260612230728652 1.0 0.8509239005860317 14 Q9Y2L1,Q96C86,Q9UIV1,Q15477 4 +Response to amino acid starvation 0.457933501234178 0.6333031773046254 0.5265356788308224 1.0 0.8513528914289739 13 P28482,P42345,Q6PKG0,P49327,Q9P2J5,Q92616 6 +Rna polymerase ii preinitiation complex assembly 0.436667584834493 0.6332186780161363 0.526590850085001 1.0 0.8513528914289739 7 P09429,Q9Y6J9 2 +Trna processing 0.4829997904570712 0.6314213421207185 0.5277650650148027 1.0 0.8524130285794365 53 Q2VPK5,Q96FX7,O15091,O60294,Q9UBP6,P57081,Q9Y3I0,Q9UET6,O75818,O95163,Q6P1R4,Q8TEA1,Q08J23,Q9BV44,Q9BQ52,Q92499,Q9H974,Q9H9T3,Q99575,P78346,O95707,Q7Z2T5,Q9UJA5,Q7Z4G4 24 +Anterograde axonal transport 0.4631802003182756 0.6294334480561942 0.5290653260196223 1.0 0.8543018246558194 15 P78559,O14617,P27695,Q9Y496,O60333 5 +Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.4565960167122817 0.6270776914454055 0.5306083095989258 1.0 0.8559467049607178 13 Q9BYG3,Q8IY81,P42766,P18124 4 +Positive regulation of endothelial cell proliferation 0.4457453038219987 0.623416420133005 0.5330109103742262 1.0 0.8591856935926184 10 P09429,P21359 2 +Regulation of protein localization to cell surface 0.4417094718119819 0.621422374863794 0.5343217540623784 1.0 0.8608736871520677 9 P78559 1 +Regulation of osteoclast differentiation 0.4213187092900206 0.6211607978211409 0.5344938300015629 1.0 0.8609385076246191 4 P21359 1 +Response to hydroxyurea 0.430039725326462 0.6209412196428383 0.5346382989800693 1.0 0.8609588390480524 6 Q9BY42,Q06787 2 +Positive regulation of rig i signaling pathway 0.4161194029850815 0.6182650134800042 0.5364006604133371 1.0 0.8627330818963279 3 Q9NUD5,O75179 2 +Cell substrate junction organization 0.4847880676825105 0.6160137686954469 0.5378854325295941 1.0 0.8646951931113366 26 Q9H2G2,Q9HCM4,P63167,Q9UPN3,Q13464,O75116,P51452,Q9P1Y5,Q7Z460,Q6DN90,Q9P258,Q14155 12 +Regulation of telomere capping 0.4400038333675273 0.6135492048640306 0.5395132582310489 1.0 0.8660328358526916 9 Q13315 1 +Histone h3 acetylation 0.4640084728901943 0.6073459967669409 0.543621319054584 1.0 0.8700605915260866 17 Q9UPT9,Q9Y4A5 2 +Positive regulation of glial cell differentiation 0.4307603336653188 0.6059217981557881 0.5445666837815923 1.0 0.8702293418948801 7 O14744,Q15382,P42345 3 +Negative regulation of potassium ion transport 0.4134328358209039 0.6058391896507551 0.5446215432997561 1.0 0.8702293418948801 3 O95747,Q12955 2 +Negative regulation of potassium ion transmembrane transport 0.4134328358209039 0.6058391896507551 0.5446215432997561 1.0 0.8702293418948801 3 O95747,Q12955 2 +Protein dephosphorylation 0.420286673438182 0.6057818550648367 0.5446596202640697 1.0 0.8702293418948801 72 P49841,Q99504,O75116,Q08209,Q8TF05,Q13526,Q13614,Q12923,Q9UNI6,Q69YH5,P51452,Q99956,P42858,Q9ULE6,P67870,P63151,Q06124,Q96P16,P30307,O60942,P42345,Q15257,O95248,P62942,P63167,Q13555,Q13464,Q96GX5,Q14738,Q8NCE2,O00743 31 +Somatic diversification of immune receptors via somatic mutation 0.42221757493125 0.6048055110401014 0.5453082314302098 1.0 0.8710525321035396 5 P52701 1 +Nucleoside monophosphate biosynthetic process 0.4823170102692871 0.6042871757188962 0.545652731009993 1.0 0.8713896633639654 26 P00492,P07741,Q01433,P31939,P04818,P04183,P27708,P11908,Q969G6,P11172,P49915,P33316,P12268,P20839,O15067 15 +Cytoplasmic translational initiation 0.4729561137954861 0.6039433421681525 0.5458813115674706 1.0 0.8715415561211693 21 Q9ULC4,P41214,Q04637,P42345,Q7Z478,P40429,Q14152,Q14240 8 +Regeneration 0.4904148953408479 0.6031227610708868 0.546427025716351 1.0 0.8717733882061501 34 P00374,Q15648,O14965,Q9HAU5,P31939,P62841,Q99707,Q7Z4V5,P20248,P19784,P46821,O14744,P04818,P11908 14 +Smooth muscle contraction 0.440852469681579 0.6008847417586324 0.5479167566095173 1.0 0.8733852317661461 10 O75116 1 +Cellular response to leptin stimulus 0.4168239527418186 0.6004178952985221 0.5482277644314362 1.0 0.8733852317661461 4 P20248 1 +Response to leptin 0.4168239527418186 0.6004178952985221 0.5482277644314362 1.0 0.8733852317661461 4 P20248 1 +Integrin activation 0.4165140214177467 0.5989952175330315 0.5491760737567835 1.0 0.8733852317661461 4 Q9Y490,Q15058 2 +Muscle cell migration 0.4437945068990281 0.5984137866098234 0.549563868920681 1.0 0.8737891560876666 11 P27695,Q13464,P31949,Q96N67 4 +Cell proliferation in forebrain 0.4204628737973508 0.5967576600632235 0.550669189815751 1.0 0.8751204209045641 5 Q15058,Q96N67 2 +Negative regulation of viral genome replication 0.4464453585546677 0.5951802947569735 0.5517229606450456 1.0 0.8759894670371962 12 P78362 1 +Dna catabolic process 0.4321863981526158 0.5948058176848547 0.5519732783306428 1.0 0.8759894670371962 8 P27695,Q13315 2 +Regulation of monooxygenase activity 0.4355059331705718 0.5929322014195331 0.5532265265390006 1.0 0.8774761278357236 9 P00374 1 +Trna modification 0.4887038274803885 0.5923987287803717 0.5535836173945659 1.0 0.8778292913031848 35 P57081,Q2VPK5,Q9UET6,Q96FX7,Q9H974,Q9H9T3,O95163,Q6P1R4,Q8TEA1,Q7Z2T5,Q08J23,O60294,Q9UJA5,Q7Z4G4,Q9UBP6 15 +Positive regulation of cell division 0.4576157289729394 0.5905052512674681 0.5548519662164706 1.0 0.878986739299746 16 Q9H8V3,Q15058,P67809,P60953,Q8IXJ6,Q96Q89,Q16513,P61586,Q13618 9 +Inositol metabolic process 0.4093243557259677 0.5869805566982067 0.5572167651271518 1.0 0.8820910245528003 3 Q13572 1 +Postreplication repair 0.4409876753575788 0.5856140893852917 0.5581348780618312 1.0 0.8826884848011037 11 P28340 1 +Response to gamma radiation 0.4641562913438491 0.5845260681028591 0.5588664321101331 1.0 0.8827764396901715 19 O96017,P49917,P22681,P09874,Q13535,Q13315,P78527 7 +T helper 17 type immune response 0.4083706226795734 0.5826284027670469 0.5601434808113579 1.0 0.8837247957714827 3 Q9UDY8 1 +Smooth muscle cell migration 0.4331370295621091 0.5821613091188547 0.5604580319060704 1.0 0.8837939986347838 9 P27695,P31949,Q96N67 3 +Positive regulation of wnt signaling pathway 0.4699507604128465 0.5802065013197335 0.5617753699304227 1.0 0.88539250398174 22 Q96QK1,Q70CQ2,P98170,P68400,Q9UPN3,P40818,Q13526,P51532,O95071,Q96K76,Q13418 11 +Positive regulation of microtubule polymerization or depolymerization 0.4604148484050256 0.57881169643208 0.5627162380821138 1.0 0.8862848612340094 18 Q16512,Q14008,Q9Y295,Q99996,Q7Z460,P46821 6 +Negative regulation of establishment of protein localization to mitochondrion 0.4070527412141818 0.5766308420922149 0.5641888597824241 1.0 0.8879617388236271 3 P31689 1 +Stem cell division 0.415812463160475 0.5755876641861184 0.5648939210428525 1.0 0.8886430509298547 5 Q13618 1 +Plasma membrane to endosome transport 0.4019695613249713 0.5747779204716288 0.5654415011703162 1.0 0.8888739932442833 2 P61020 1 +Fibroblast activation 0.4111567110239674 0.5745654662895235 0.5655852131592645 1.0 0.8888739932442833 4 Q15418,P48507 2 +Hepatic stellate cell activation 0.4111567110239674 0.5745654662895235 0.5655852131592645 1.0 0.8888739932442833 4 Q15418,P48507 2 +Immune response 0.2041007439506758 0.5741984981909737 0.5658334854852054 1.0 0.8890502069822885 227 O75569,Q15648,Q96EP0,Q9UIV1,P40429,P49327,Q13144,Q9BUI4,Q9Y3Z3,Q96FZ2,Q9UII4,O00178,P78362,P52701,P07814,P14174,P51452,Q03518,Q01804,Q13309,Q96BN8,P40763,P78527,Q92499,Q6GQQ9,Q92908,Q06124,P49917,Q96QE3,P55212,P42345,P36915,O00203,Q8IXJ6,Q8IWZ3,P62753,O14802,Q9UDY8,Q96FW1,Q96SB4,P62942,O15111,Q14258,Q16512,P09429,P28482,P22681,P60953,Q9NW08,Q92974,Q92538,O95373 52 +Regulation of erythrocyte differentiation 0.4481289558765368 0.5739636103189337 0.5659924263760501 1.0 0.8890860101601171 14 Q15648,P40763,P78527,Q00534 4 +Organelle fission 0.2174679480449416 0.5733259407666619 0.566424024409844 1.0 0.8893361094965813 163 Q15398,O43670,Q13526,Q6IBW4,Q6NUK4,Q9GZZ1,Q99661,P42695,O00139,O14965,Q69YH5,Q15058,Q15021,Q14999,P50748,P61160,P83731,P46379,Q86XI2,P61586,Q15645,Q99741,Q969U7,Q96QK1,P30307,Q9UDX5,Q9UJX5,O00203,Q29RF7,Q8WUX9,Q9UIG0,O00429,Q9Y295,Q9Y620,Q8IXJ6,Q96Q89,P14635,Q5JVF3,Q9NTJ3,Q13315,O14744,Q9BPX3,O96017,Q15003,O95067,Q9BW19,Q9NTI5,P60953,Q14674,Q96GX5,Q9H6H4,Q9H900,Q7Z460,Q27J81,P53350,Q13618,Q99640 57 +Response to platelet derived growth factor 0.4307772702761856 0.5714940842190366 0.5676647692807788 1.0 0.8908557902916332 9 P46940,P22681,P20248 3 +Positive regulation of multicellular organism growth 0.4228667897008815 0.5700166789862124 0.5686663856469343 1.0 0.8915705878210037 7 Q9P2D1 1 +Modification of synaptic structure 0.4257990442182354 0.5658765690013107 0.5714776907740622 1.0 0.8946893600466618 8 Q9UQB8,P60953,P61586,Q7L576 4 +Positive regulation of protein targeting to membrane 0.421825518171196 0.5653318124651322 0.5718480944996127 1.0 0.8948401766313134 7 Q00535,Q12955,Q9UHD1,P31751 4 +Purine nucleotide catabolic process 0.4361158270347524 0.5636076843149225 0.5730211560220415 1.0 0.8961214291679566 11 Q96DE0,O00154,Q9Y3Z3 3 +Multi organism reproductive process 0.2186236460058689 0.5631002153190989 0.5733666448893513 1.0 0.8961609033089767 155 Q93008,Q4G0J3,P52701,O14965,Q5TAX3,P25440,Q14997,Q8NB78,Q96RD7,P47914,Q14353,P30307,P42345,O00203,P50570,Q8NHU6,Q8IXJ6,Q96CW5,P19784,O95248,P62753,Q13315,Q96SB4,O75592,O95067,P35579,P53350,Q6P6C2,Q9H6S0 29 +Positive regulation of stem cell proliferation 0.4084801433263604 0.5624785623984448 0.5737900056255485 1.0 0.8961609033089767 4 Q96AC1,O60341,Q00839 3 +Dna damage response signal transduction resulting in transcription 0.4082171756789138 0.5612954419819476 0.5745961483092157 1.0 0.8970613116718513 4 O96017,P61254 2 +Amyloid beta clearance 0.4283227342660553 0.5604659402917931 0.5751616652204576 1.0 0.8974446054694356 9 P04035,Q16850,Q13464,Q00610 4 +Cytoplasmic microtubule organization 0.4562457415709197 0.5598806198516738 0.5755608686134415 1.0 0.8976652100665815 18 Q9H2G2,Q14203,Q9P1Y5,Q96CW5,Q14204,Q9BSJ2,Q7Z460,P61586,P43034 9 +Cellular component disassembly 0.2175239059199148 0.5576518160946754 0.5770821662387517 1.0 0.8993667173124222 159 P49841,O95352,P62136,P51532,Q00535,A1X283,Q13190,Q6DN90,Q99661,Q9ULC4,Q14203,P51452,P35241,P42858,Q13045,Q9UBB9,Q08945,Q9Y3I1,Q9H269,Q9NT62,P17096,Q7Z6Z7,Q9P1Y5,Q8WUX9,O00429,Q7KZI7,P19784,P47755,O14976,Q13501,Q9BPX3,P46821,Q14562,P78559,Q14008,P41214,P29372,Q9Y4P1,P50851,Q92974,P63241,Q99986,Q7Z460,Q92538,Q99570,Q9UHB6,P53350,Q9Y5B9,Q66K74,Q99816 50 +Neurotransmitter receptor transport endosome to postsynaptic membrane 0.4026865671641867 0.5568994748529987 0.5775961134500491 1.0 0.8997382206175623 3 Q14160,Q96QK1 2 +Neurotransmitter receptor transport to plasma membrane 0.4026865671641867 0.5568994748529987 0.5775961134500491 1.0 0.8997382206175623 3 Q14160,Q96QK1 2 +Regulation of epidermis development 0.4339911074603159 0.554096748779264 0.5795126350690603 1.0 0.9009906184221976 11 P22392,Q15648,O75116 3 +Negative regulation of neuron differentiation 0.4191281778147343 0.5532543123696896 0.5800892810410168 1.0 0.9012569605514724 7 Q15648,P49841,P26196,P61586,O60271 5 +Utp metabolic process 0.4105732292486662 0.5520262134191589 0.5809303937406458 1.0 0.9014913191840346 5 P15531,P27708 2 +Positive regulation of viral genome replication 0.4568204742051156 0.5511818399259086 0.5815090276807444 1.0 0.9021748516881114 19 Q6PKG0,P78362,Q9UIV1,Q96SB4 4 +Energy reserve metabolic process 0.4563211077480504 0.5489363276448964 0.5830491466800178 1.0 0.904134630211474 19 P49841,P06737,P42345,P31751,P62136,Q15185,P46976,P35573,P08237,P11216,P13807,Q06210 12 +Cardioblast differentiation 0.400184474279409 0.5456912489898518 0.5852781883245428 1.0 0.9071603536100794 3 Q92908 1 +Response to interferon alpha 0.4088402676025838 0.5443032740890449 0.586232794278138 1.0 0.9077780760342048 5 P10155 1 +Positive regulation of helicase activity 0.4082182619163797 0.5415400815345562 0.588135378697749 1.0 0.909801629432893 5 P52701,P20585 2 +Body fluid secretion 0.4437485961284328 0.5408873416498785 0.5885852363502657 1.0 0.909801629432893 15 O75592,Q15648,P07741,P53621,Q9UNS2,P15531 6 +Regulation of microtubule polymerization or depolymerization 0.4767760946154704 0.5408503070015663 0.5886107647875922 1.0 0.909801629432893 33 Q14203,P04350,Q16512,Q8WWK9,P78559,Q14008,P29372,Q9P1Y5,Q92974,O15344,Q9Y295,Q99996,Q7Z460,P46821,Q9BTW9,Q66K74,Q14155 17 +Cell junction maintenance 0.4163234358671556 0.5407873055693764 0.5886541936223542 1.0 0.909801629432893 7 Q15334,Q9P1Y5 2 +Pyrimidine containing compound biosynthetic process 0.437250460139051 0.5392157781678631 0.5897379745165761 1.0 0.9109381371941409 13 P22392,P42345,P15531,P17812,P27708,P33316,P04818 7 +Negative regulation of plasma membrane bounded cell projection assembly 0.4118859054497986 0.5387231136753933 0.5900779226332922 1.0 0.9109381371941409 6 P47756,P50570,P27816 3 +Regulation of dna damage response signal transduction by p53 class mediator 0.4338885801032175 0.5386917377890338 0.5900995756643996 1.0 0.9109381371941409 12 P14174,Q13535,P61254,Q13315 4 +Regulation of microtubule based process 0.3974588411285269 0.5386739517144312 0.5901118502985545 1.0 0.9109381371941409 75 P49841,Q9UHD1,O75116,Q14203,O14965,O14980,Q8NI35,Q9UPN3,O60610,Q14204,P61586,P04350,Q8WWK9,Q8WUX9,Q9P1Y5,Q00610,Q9Y295,Q7KZI7,Q14155,P43034,Q16512,P78559,P57076,Q14008,P27695,Q13464,P29372,Q92974,Q99996,Q7Z460,P53350,P46821,Q9BTW9,Q66K74 34 +Hippocampus development 0.4488467258221305 0.5385077839490994 0.590226532690415 1.0 0.9109381371941409 17 Q9H0D6,P49841,Q15058,P42574,P46109,Q13144,Q00535,Q00534 8 +Positive regulation of stress activated protein kinase signaling cascade 0.4303352642100352 0.5378597609652859 0.590673870445287 1.0 0.911413131854377 11 P09429,P29372,P60953,O15344,Q99873 5 +Positive regulation of organic acid transport 0.4191060127475521 0.536068140139799 0.5919114581795468 1.0 0.9128913136307136 8 Q15042 1 +Cell migration 0.2030042628401168 0.5339114589230258 0.5934027936875648 1.0 0.9145170929994848 219 P31146,Q9Y263,Q14185,O75116,Q93008,P46109,Q08209,P31751,P21359,Q00535,Q9BSJ2,O43776,Q9Y2A7,Q6DN90,Q9P258,Q9Y5K6,Q9HCM4,Q15058,Q9UPN3,P14174,Q13885,P35241,P51452,O60610,O94776,P20248,P40763,Q9UH99,P31949,Q9NPQ8,P67870,Q9H2G2,Q06124,P42345,Q9H9T3,P55196,O00443,Q9P1Y5,O00429,Q92614,Q96N67,Q7KZI7,Q96Q89,Q16513,Q13315,O60271,Q14155,Q13418,Q16512,P63167,P09429,P27695,Q13464,Q6PJG6,P28482,P30046,P60953,P35579,P42785,Q92974,P46940,Q7Z460,Q92538,Q9UHB6,P46821,O00401,Q13618 67 +Synaptic vesicle recycling 0.4419731570591969 0.5330216676573973 0.5940185813737862 1.0 0.9145170929994848 15 O14617,Q9Y263,O00203,P50570,Q00535,O14976 6 +Cell substrate adhesion 0.4632621556504009 0.5329019244479366 0.5941014729992764 1.0 0.9145170929994848 54 P49841,P31146,Q14185,O75116,P46109,P21359,P42771,Q00535,Q9P258,Q9UL63,Q9HCM4,Q15058,Q9UPN3,P51452,P20248,Q00534,Q9H2G2,P50570,Q9P1Y5,Q14155,Q13418,P63167,Q13464,P60953,Q7Z460,Q9BTW9 26 +Deoxyribose phosphate metabolic process 0.4357695919478183 0.5326725303693014 0.594260284651509 1.0 0.9145170929994848 13 Q96DE0,P04818,P23921,Q9Y3Z3 4 +Positive regulation of actin filament bundle assembly 0.438737037062676 0.5319860552472881 0.5947356536688204 1.0 0.9145170929994848 14 Q16512,O75116,Q9Y613,P42345 4 +T cell differentiation 0.4681531955873328 0.5315739020444076 0.5950211441824469 1.0 0.9146610375864364 27 P49917,P09429,O14617,Q9UDY8,P42345,O00203,P62753,Q00534,Q9P2D1,O43290,P78527 11 +Protein targeting to lysosome 0.4179171332888879 0.5308302060048431 0.5955364462265227 1.0 0.9146610375864364 8 P20645,Q7Z3T8 2 +Dna damage response signal transduction by p53 class mediator 0.4471017431594025 0.5307670673507261 0.5955802039536795 1.0 0.9146610375864364 17 O96017,Q9UM54,P14174,P61254,Q13535,Q13315 6 +Positive regulation of plasma membrane bounded cell projection assembly 0.4687674472375479 0.5279358272414265 0.5975438770465327 1.0 0.9168198286206852 28 P49841,P27695,Q06787,P61160,P42345,P50570,P60953,P42858,P07737,Q9Y2A7,Q7L576,Q8NCA5,O00401,Q8WUW1 14 +Positive regulation of neuron differentiation 0.424584858953681 0.5278911439547909 0.597574891764163 1.0 0.9168198286206852 10 Q9H8V3,Q04637,Q92974,P46821,O60271 5 +Barbed end actin filament capping 0.4280349406490267 0.527728335339 0.5976879035893197 1.0 0.9168198286206852 11 P35241,Q9BPX3,P47755 3 +Axonal transport 0.4581107756119578 0.5264985235190042 0.5985418776017304 1.0 0.9168375465022988 22 P78559,Q9NZ32,O14617,P27695,Q9Y496,Q14204,O60333 7 +Cilium movement 0.4203803242143716 0.5252750159959112 0.5993920228257017 1.0 0.9170641773785922 9 Q86Y56,P57076,Q9P1Y5 3 +Regulation of stem cell proliferation 0.4087242306543185 0.5247942058227575 0.5997262598887632 1.0 0.9173606177263114 6 P19525,P26583,Q96AC1,Q00839,O60341 5 +Regulation of cation channel activity 0.4428794572988069 0.5243152700778603 0.6000592777906724 1.0 0.9175178762303272 16 P27695,Q06787,P42858,Q00535,Q15334,P62942 6 +Negative regulation of organelle organization 0.2162435056229263 0.5238121742706625 0.6004091849536923 1.0 0.9175455131634944 114 P31146,P09874,O43670,Q8IZH2,Q15554,P50748,P35241,Q13045,P04350,Q969U7,Q8WWK9,Q7Z6Z7,P50570,Q9P1Y5,P14635,Q5JVF3,P47755,Q13315,Q9BPX3,P33993,Q14155,O75832,P63167,P29372,Q14674,Q92974,Q9H900,Q7Z460,Q7Z5K2,Q9UHB6,P53350,P46821,Q9BTW9 33 +Fructose metabolic process 0.3995493602361692 0.5227575979969142 0.6011429503886603 1.0 0.9176078923655188 4 P09972,Q00796 2 +Protein nitrosylation 0.3903312444046538 0.5226313222781435 0.6012308391252867 1.0 0.9176078923655188 2 P04406 1 +Regulation of microtubule based movement 0.4038173750871318 0.5221252987543458 0.6015830930342603 1.0 0.9176078923655188 5 P27695 1 +Ribonucleoside monophosphate biosynthetic process 0.4570857433859471 0.5219362747233759 0.6017147006292727 1.0 0.9176078923655188 22 P00492,P07741,Q01433,P31939,P27708,P11908,Q969G6,P11172,P49915,P12268,P20839,O15067 12 +Intermediate filament bundle assembly 0.3900328260220808 0.5213158124039933 0.6021467874956474 1.0 0.9180524217479752 2 P58107 1 +Nucleotide sugar metabolic process 0.4329414719506191 0.5202545851773751 0.602886144784252 1.0 0.9189651086463972 13 Q9NR45,O60701,Q06210,Q9Y223 4 +Regulation of double strand break repair via nonhomologous end joining 0.4227788416264157 0.5199851191304625 0.603073946877295 1.0 0.9190368431992384 10 Q9BRJ7,Q9UBB9,A6NHR9,P78527 4 +Lactation 0.4295844064276555 0.5197707775931252 0.6032233491996384 1.0 0.9190500397278673 12 O75592,Q15648,P07741,Q9UNS2,P15531 5 +Erbb signaling pathway 0.4542351162068369 0.5188505546212894 0.6038649606089519 1.0 0.9198129677575124 21 Q06124,P27695,P28482,P51452,O00443,P46940,Q99816 7 +Ribosomal large subunit export from nucleus 0.4111741116704829 0.518150649740681 0.6043531637716226 1.0 0.9203419215085578 7 Q9NVU7,Q96D46 2 +Morphogenesis of an endothelium 0.397760402914584 0.5149192271084276 0.6066094645324878 1.0 0.923132091213504 4 P67870 1 +Nucleus localization 0.4374809954979095 0.5133034696587304 0.6077390572986969 1.0 0.9239897658115228 15 P42345,P60953,Q96N67,Q14204,Q9UH99,Q9Y613 6 +Ventricular cardiac muscle tissue development 0.4135448488037017 0.511721046275261 0.608846254327259 1.0 0.925411558636803 8 Q9P2D1,P62942 2 +Positive regulation of actin filament depolymerization 0.3922388059701583 0.5106041067505783 0.6096282996340241 1.0 0.9259997200768032 3 P60981,Q9Y281 2 +Regulation of chondrocyte differentiation 0.4010236788188187 0.509927570807748 0.6101022054478331 1.0 0.9264435870297536 5 Q9C0E8 1 +Regulation of myoblast differentiation 0.396536279486412 0.5095794232418267 0.6103461426343031 1.0 0.9264435870297536 4 Q8IWT6,Q16539,Q14254 3 +Positive regulation of epithelial cell apoptotic process 0.3958675071359689 0.5066703908917782 0.6123861092142202 1.0 0.9281357832557195 4 P19174 1 +Ribosomal large subunit assembly 0.455649937102665 0.5065709300588023 0.6124559096552673 1.0 0.9281357832557195 23 P39023,P83731,Q02878,Q9NUL7,P27635 5 +Membrane disassembly 0.404260562316992 0.505345318659138 0.6133163178220755 1.0 0.9292240267698731 6 Q14203,Q99986,P53350 3 +Interferon beta production 0.4322914847831462 0.5038274152310821 0.6143826607116241 1.0 0.929976535569519 14 Q9NW08,Q9BUI4,O14802 3 +Positive regulation of blood pressure 0.3904477611940375 0.5028061045446688 0.6151006012877598 1.0 0.9306557496201596 3 Q9H4A3,P61586 2 +Regulation of microtubule polymerization 0.4567112580561558 0.5027836090251098 0.6151164188913643 1.0 0.9306557496201596 24 Q14203,Q16512,P04350,Q14008,Q9P1Y5,Q9Y295,Q99996,Q7Z460,P46821,Q9BTW9 10 +Prosthetic group metabolic process 0.3947446999104201 0.5017996395013967 0.6158084667437169 1.0 0.931271257025584 4 Q9NQX3,O96007,Q9NZB8 3 +Transcription by rna polymerase iii 0.4524147717509638 0.5013332443548489 0.6161366123467329 1.0 0.931551766294088 22 P42345,P30044,Q9NY93,Q659A1,Q9UIG0,O75533,P10155,Q9H2U1,Q8WUA4,Q12789,Q9NR30,Q9BUI4,Q9BQG0,Q9HCK8 14 +Detection of light stimulus 0.3984124578533504 0.49861870260905 0.6180480269217057 1.0 0.9342253740274856 5 O96017,Q13432,P30419 3 +Negative regulation of catalytic activity 0.2134943759229817 0.4981236350911316 0.618396902685727 1.0 0.9344945011771572 161 P49841,Q9UHD1,P68400,O00170,O75116,Q9Y570,P42771,P21359,Q8TBX8,Q9P258,Q9Y314,Q86VP6,P98170,Q15554,P62081,P51452,P35241,P62841,P61927,P23381,P46777,Q9UBB9,Q86XI2,Q14558,P29375,Q96B36,Q9Y3I1,Q9GZT9,Q96QC0,P42574,Q15257,P30044,P60866,Q15418,P49407,O43924,Q5JVF3,Q14240,O60256,P61221,P31689,Q9P0V3,P33993,P06744,Q9NR09,P62942,P47897,P62829,P63244,P78318,Q16512,Q13464,P22681,P04035,Q96GX5,Q99996,P46940,P53350,Q14684,O95373,O00410,Q99816 62 +Positive regulation of execution phase of apoptosis 0.3893297507700242 0.4979599273860176 0.6185122869965809 1.0 0.9344945011771572 3 Q8IXJ6 1 +Organelle transport along microtubule 0.4630485815033995 0.4962950570630583 0.6196862531900096 1.0 0.9356187822730088 29 Q9UBF2,O14617,P27695,P42858,Q9Y496,Q14204,P46821,Q9Y678,Q66K74,Q9NZ32 10 +Animal organ regeneration 0.4442728964885803 0.4957627079717051 0.6200618385516123 1.0 0.9358465764952126 19 O14965,Q15648,Q9HAU5,P31939,P62841,P20248,P19784,P04818,P11908 9 +Regulation of calcium ion dependent exocytosis 0.3977292825757673 0.4956749584660863 0.6201237575030298 1.0 0.9358465764952126 5 Q15042 1 +Regulation of lymphocyte migration 0.405886710518662 0.4952624407921249 0.6204148796932414 1.0 0.9360695851194238 7 P46109,O00401 2 +Cellular oxidant detoxification 0.4548754009927134 0.4947195289723656 0.6207981143616204 1.0 0.9361670519609048 24 P00374 1 +Regulation of vesicle mediated transport 0.2147634678296141 0.4932475781376167 0.6218376637334742 1.0 0.9369173844438362 117 P36507,P49841,Q7Z3T8,P31146,Q08209,Q13614,P31751,Q00535,O75165,Q9P2R3,Q9UL63,Q9Y5K6,P35241,Q9Y6B6,Q9NT62,Q9H4M9,Q96T51,P50570,P49407,Q92614,P09429,P27695,Q13464,Q06787,P28482,P22681,P60953,Q15042,Q9H223,Q7Z460,Q15334,O00401,Q99816 33 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.412397878632278 0.4907175273062596 0.6236262480513837 1.0 0.9376212100873582 9 Q8WUX9,Q9Y263 2 +Nuclear chromosome segregation 0.2138945025732906 0.4902901443995416 0.6239286000761703 1.0 0.9376878615644172 114 Q15398,O43670,Q9P258,Q6IBW4,Q9GZZ1,Q99661,P42695,Q15058,Q15021,P50748,Q14204,Q99741,Q969U7,Q9H8V3,Q9UJX5,Q29RF7,Q8WUX9,Q8IXJ6,P14635,Q5JVF3,Q9NTJ3,Q13315,Q9BPX3,Q15003,Q9BW19,Q9NTI5,P60953,Q14674,Q9BTE3,Q9H900,Q7Z5K2,P53350,Q13618 33 +Positive regulation of rna metabolic process 0.1958800913304621 0.4890050459790628 0.624838124450692 1.0 0.9388386913628668 364 Q9UM54,O75569,Q15648,Q9UPT9,Q9UPP1,Q9UIV1,P67809,P09874,O00170,O75116,Q86W50,A5YKK6,P10589,P51532,Q6P1K2,O75909,Q3B7T1,Q4G0J3,Q9H3P2,Q9P2D1,Q9UER7,Q96D46,Q9Y5V3,Q86VP6,Q5TAX3,O43709,Q9Y2L1,Q86TU7,Q9NYV4,Q8NB78,P29375,P78527,Q9HCE1,P17096,Q86TB9,P42345,O00203,P50570,P49407,Q8IXJ6,Q5JVF3,Q13315,Q92616,Q9Y613,Q13501,Q7L2J0,O15111,Q9HCK8,O96017,Q14258,P09429,O14617,P27695,Q16512,P22392,P63241,P35251,P85037,Q9Y2X0,P08237,Q96C86,Q9Y2X9,O75155,Q99816 64 +Stress granule assembly 0.4345568996908185 0.4881773054759946 0.6254242579981484 1.0 0.9395031986951712 16 Q9Y520,Q14204,P62266 3 +Endoplasmic reticulum tubular network organization 0.4220613939089495 0.4872883542846534 0.6260539994219474 1.0 0.9402238035586472 12 Q9C0E8,Q9H6H4,Q15042 3 +Activation of gtpase activity 0.4365813103904069 0.4849702578645297 0.6276974432997533 1.0 0.9416182643573142 17 Q9H8V3,Q8TC07,P46109,P31751,Q96N67,Q86X10,Q9P258 7 +Regulation of plasma membrane organization 0.3906959877825858 0.4843769321369598 0.6281183865070799 1.0 0.9420333173842974 4 P35579,P50570 2 +Cellular response to gamma radiation 0.4178174555648536 0.4835668740730737 0.6286932888303696 1.0 0.9424654177896103 11 O96017,Q13535,Q13315 3 +Positive regulation of metaphase anaphase transition of cell cycle 0.4104451979508572 0.4823953400143935 0.6295251308635785 1.0 0.9427041594725932 9 Q9UJX5,Q14674,Q15398 3 +Cellular component maintenance 0.4173948006802931 0.4817709016647593 0.6299687024371998 1.0 0.9427041594725932 11 Q14203,Q9C0E8,Q9P1Y5,Q13614,Q15334 5 +Protein localization to golgi apparatus 0.4064673568614488 0.4813249086274218 0.6302855965816911 1.0 0.9427041594725932 8 Q92538,Q5THJ4,O14976 3 +Artery development 0.4137486474885904 0.4811042193134 0.6304424294665871 1.0 0.9427041594725932 10 Q9ULT8,P21359 2 +Hepatocyte differentiation 0.3801850193971917 0.4785588556628304 0.6322524945736903 1.0 0.9445455935864098 2 Q16822 1 +Cell growth 0.210884347813191 0.4765232554686813 0.633701643584877 1.0 0.9452206055461008 107 O14681,P49841,Q9BRT6,P68400,Q9Y263,Q93008,P46109,Q7Z4V5,P51532,P42771,Q00535,Q7L576,Q9HCM4,O14965,Q15058,Q9UPN3,Q96F07,P42345,P50570,Q15418,O60271,Q9P0V3,O75832,Q04637,Q6PJG6,P60953,P46940,Q9P265,P46821,Q99816 30 +Positive regulation of interleukin 6 production 0.4052907354466978 0.4763385794315649 0.6338331845830236 1.0 0.9452206055461008 8 Q06124,P09429,P40763 3 +Microtubule nucleation 0.4288623982332616 0.476244526652487 0.633900180918906 1.0 0.9452206055461008 15 Q16512,Q14203,Q14008,Q96P70,Q99996,Q96CW5,Q9BSJ2,Q7Z460 8 +Regulation of chromatin assembly or disassembly 0.4256596107384113 0.4754491648875154 0.6344668585431439 1.0 0.9453069808329492 14 Q9UPP1,P26358 2 +Phosphatidylinositol metabolic process 0.4555274713959343 0.4754036260962972 0.6344993104120698 1.0 0.9453069808329492 27 O96017,O15357,O00443,P42356,Q01968,Q08AM6,Q99570,Q13315,Q8NCE2 9 +Positive regulation of interleukin 1 beta production 0.397070702757789 0.4745773412413378 0.6350882597818517 1.0 0.9459685986257964 6 Q9UDY8,Q96RD7 2 +Cellular nitrogen compound catabolic process 0.2088369418504974 0.4739817255923014 0.6355129388172835 1.0 0.9463852885922148 172 P67809,O75116,Q8IZH2,Q86W50,A5YKK6,Q13126,Q96DE0,Q96HR8,Q5TAX3,Q9Y2L1,Q9HCE1,Q86TB9,Q99575,Q9GZR2,Q13315,O00154,Q15477,Q9Y2V2,P27695,Q14147,Q6PKG0,Q96C86,Q9BPU6,Q6P6C2 24 +Regulation of early endosome to late endosome transport 0.418757725231409 0.4732723329947506 0.6360188982315618 1.0 0.9465790454519803 12 O75165,P36507,P28482,Q13614 4 +Response to radiation 0.2959491036949964 0.4729863976387315 0.6362228836889345 1.0 0.9465790454519803 92 Q9UNS2,P09874,Q99504,Q92547,Q13432,P30419,P62136,P21359,P54132,P31751,Q00535,Q13535,P28340,Q9UPY5,P52701,Q68E01,P10155,Q9NPQ8,P78527,P18074,P49917,Q9H8V3,P42574,P50570,Q9Y620,Q96RU2,Q13315,O96017,O60921,Q06787,Q6PJG6,P22681,P04035,P61254,Q13620 35 +Positive regulation of jnk cascade 0.3965356072726733 0.4723162030951405 0.6367011066362631 1.0 0.9470747170768076 6 P60953,P09429 2 +Postsynaptic modulation of chemical synaptic transmission 0.3920142072437437 0.47130037871349 0.6374262452607304 1.0 0.9470747170768076 5 P40818,Q08209,Q7L576 3 +Positive regulation of calcium ion transmembrane transporter activity 0.4074345384829932 0.4696695676294074 0.638591113515671 1.0 0.9482833866852912 9 P42858 1 +Negative regulation of histone h3 k27 methylation 0.3777976723366139 0.4683934724246283 0.6395032351790992 1.0 0.9490809376635267 2 Q7KZ85 1 +B cell differentiation 0.4206103544376707 0.4673765885933494 0.6402304693820184 1.0 0.9499443228958372 13 Q9UDY8,P78527,Q13315 3 +Pyrimidine ribonucleotide metabolic process 0.4065739415777148 0.4660558487840985 0.6411755251091327 1.0 0.951130435929722 9 P15531,P17812,P27708 3 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.4319607977844824 0.4653549944679043 0.6416772580079722 1.0 0.9515555122081631 17 O96017,P55212,P62081,P14174,P61254,P63241,Q96RU2 7 +Exonucleolytic catabolism of deadenylated mrna 0.406316543767126 0.4649771083741053 0.6419478498928839 1.0 0.9515555122081631 9 Q9Y2L1,Q96C86 2 +Neuron projection organization 0.4479692293651899 0.4648415091064736 0.6420449596920623 1.0 0.9515555122081631 24 Q14203,Q96QK1,P78559,P49841,P61160,Q05086,P60953,Q13614,Q00535,O60678,Q9UQB8,Q15334,O00401,P43034 14 +Negative regulation of neural precursor cell proliferation 0.3900039398955961 0.462836324333366 0.6434816922210089 1.0 0.9531231171528892 5 Q8IXJ6 1 +Aspartate family amino acid biosynthetic process 0.4159278209285816 0.461392042292211 0.6445173597356868 1.0 0.9539207522833262 12 Q13126 1 +Negative regulation of microtubule polymerization 0.393792061854876 0.4607875244282049 0.6449510531919356 1.0 0.9542297317088552 6 Q9BTW9 1 +Cytokine production 0.2103610957714131 0.4605485376690072 0.6451225405032932 1.0 0.9542297317088552 109 P09429,Q6GQQ9,P30046,P14174,O75116,Q9NW08,Q9BUI4,P49407,P46940,O14802,Q96RD7,Q9UDY8,Q9HCL2,Q9Y6D5,Q9Y5K6,O15111 16 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.3850566909044191 0.4604900492429785 0.6451645123268905 1.0 0.9542297317088552 4 Q96IU4 1 +Positive regulation of autophagy of mitochondrion 0.4012895459740858 0.459530750049616 0.6458530753454448 1.0 0.9548156173886696 8 P42858 1 +Golgi to lysosome transport 0.3846565381426476 0.4588124811027776 0.6463688311573845 1.0 0.9549295175243712 4 Q9P2R3 1 +Myeloid leukocyte cytokine production 0.4045823133230986 0.4577344036307422 0.6471432678760327 1.0 0.9558573940806364 9 P14174,Q9NY93,Q92499,Q9H2U1 4 +Lens fiber cell differentiation 0.3796486474495715 0.4567176376694142 0.6478740117635962 1.0 0.956720329447373 3 Q8NHU6 1 +Polysaccharide metabolic process 0.439483550340715 0.4551801026378875 0.6489796739159563 1.0 0.9570544875047864 21 O43505,P49841,P06737,Q93100,P31751,P62136,Q00610,Q15185,P46976,P35573,P08237,P11216,P13807 13 +Response to ischemia 0.4174332037380872 0.4541060650905447 0.6497524881311356 1.0 0.9572805651367388 13 O75116,Q96RD7 2 +Regulation of sequestering of triglyceride 0.383398029262469 0.4535517885129164 0.6501514604704881 1.0 0.9572805651367388 4 O60664,Q9BXB4,Q8WTS1 3 +Sequestering of triglyceride 0.383398029262469 0.4535517885129164 0.6501514604704881 1.0 0.9572805651367388 4 O60664,Q9BXB4,Q8WTS1 3 +Innate immune response 0.2134248221325676 0.4527198467808136 0.650750486465582 1.0 0.9578801385607968 134 Q9UIV1,P40429,Q9BUI4,Q9UII4,P78362,P07814,P14174,Q01804,Q13309,Q96BN8,P78527,Q06124,P55212,Q8IXJ6,Q8IWZ3,O14802,Q9UDY8,Q96SB4,O15111,Q14258,P09429,Q9NW08 22 +Regulation of histone h3 k27 methylation 0.3779104477611984 0.4494556040831211 0.6531030274546701 1.0 0.959242718194022 3 O15294,Q7KZ85 2 +Pyrimidine nucleobase metabolic process 0.4162641461887079 0.4492614144508627 0.6532430890480649 1.0 0.959242718194022 13 P28482,P42345,P17812,P27708,Q9BPU6 5 +S adenosylmethionine metabolic process 0.3910125808369941 0.4492202834063254 0.6532727568739489 1.0 0.959242718194022 6 Q9NZL9,Q86W50,P23526 3 +Meiosis i cell cycle process 0.4400191176177531 0.4482274374078073 0.6539890630014986 1.0 0.959242718194022 22 P52701,O95067,P30307,Q14674,Q13315,P53350 6 +Dendritic spine morphogenesis 0.4276945479349607 0.4475300126232582 0.654492423005139 1.0 0.9595499600861152 17 P61160,Q05086,P60953,Q00535,O60678,Q9UQB8,Q15334,O00401,P43034 9 +Regulation of cardiac muscle cell proliferation 0.3809748595295295 0.4434892693240171 0.6574118791348307 1.0 0.961325407823764 4 Q92908,Q16539 2 +Positive regulation of cardiac muscle cell proliferation 0.3809748595295295 0.4434892693240171 0.6574118791348307 1.0 0.961325407823764 4 Q92908,Q16539 2 +Negative regulation of protein localization to nucleus 0.4010209314297557 0.4430017626692231 0.6577644597483272 1.0 0.961325407823764 9 P49841,Q6GQQ9,Q9Y5V3,P21359 4 +Labyrinthine layer development 0.4006483181826554 0.4414714781566318 0.658871705501904 1.0 0.9617635437689578 9 P28482,Q9NR09 2 +Regulation of signal transduction by p53 class mediator 0.4568031699899589 0.4401852300380561 0.6598029562726639 1.0 0.962151251554376 37 O96017,O14965,Q96QE3,P42345,P14174,P62081,P62841,P60866,P46087,P61254,P61927,P63241,P46777,Q13535,Q13315,O75832 16 +Modulation by host of viral genome replication 0.3925446016602679 0.4392394931501298 0.6604880115528682 1.0 0.9629351898727908 7 O75909,Q9H6S0 2 +Regulation of t cell receptor signaling pathway 0.4032857876099996 0.4375048608249886 0.6617452516732143 1.0 0.9639073150627012 10 Q9UDY8 1 +Cerebellar cortex formation 0.3836675748517013 0.4365481261109737 0.6624390897993742 1.0 0.9642726831007388 5 Q06124 1 +Response to fibroblast growth factor 0.4024928898354206 0.4342682981828675 0.6640936219596134 1.0 0.9661731407187164 10 Q06124,P46109,Q9UQ13,P46940,P48507 5 +Regulation of receptor clustering 0.3785862782941629 0.4336577730584143 0.6645369748845715 1.0 0.9664646873042878 4 Q9UPY5,Q15334 2 +Positive regulation of g1 s transition of mitotic cell cycle 0.4213211171870305 0.4327803397104203 0.6651743575728057 1.0 0.96696094277614 16 P31350,P27695,Q04637,P23921,P35241,Q6UVJ0,Q13620,Q7L2J0,Q99741 9 +Regulation of response to stress 0.193290373107807 0.4299938625454421 0.6672001057481953 1.0 0.9683966860492812 259 P00374,P36507,Q15648,P49841,Q96EP0,Q9UIV1,P67809,P09874,Q99504,O75116,Q5TBB1,Q7Z4V5,Q92905,P49327,O95071,Q13535,Q9UPY5,Q9BUI4,Q9UII4,Q9Y4A5,P14174,P51452,Q96L91,Q96BN8,Q9UBB9,Q00534,Q99873,P78527,Q9Y3I1,Q06124,Q96QE3,P55212,P42345,Q8IXJ6,Q13315,Q96FW1,O75832,P47897,O96017,P09429,Q16512,Q06787,P28482,Q04637,P29372,P30046,P60953,Q9NW08,Q92974,P61254,Q7Z460,O95881 52 +Cell cycle dna replication initiation 0.3858791723970476 0.4281642336569048 0.6685315540146486 1.0 0.9700694358212412 6 P33993,P09884,P33991 3 +Establishment or maintenance of bipolar cell polarity 0.4306130135111723 0.4279988428040752 0.6686519628872027 1.0 0.9700694358212412 20 Q8NI35,P60953,Q9P1Y5,Q8TEW0,Q9Y696,P18085,Q7KZI7,P61586,Q13418 9 +Regulation of phosphoprotein phosphatase activity 0.4279601605851618 0.4271332110123147 0.6692823044928267 1.0 0.9703404636630012 19 P49841,Q13464,P42345,O75116,Q15257,P42858,P67870,P62942 8 +Microtubule anchoring 0.3994442930189134 0.421916415830358 0.6730860274880532 1.0 0.9752056266911444 10 Q9Y496,Q7Z460,P49841,Q9P1Y5 4 +Negative regulation of protein containing complex disassembly 0.4410262096653003 0.4207205652017079 0.6739591422440763 1.0 0.9762540370128256 26 Q8WWK9,P29372,P35241,Q9P1Y5,Q92974,Q13045,Q7Z460,P47755,Q9UHB6,P46821,Q9BPX3 11 +Cellular carbohydrate biosynthetic process 0.4209080601731081 0.4197676938003575 0.6746551675409056 1.0 0.9764622094801444 17 O43505,P49841,P31751,P62136,Q15185,P46976,P35573,P13807 8 +Nuclear migration 0.4117205580186789 0.4179386040758243 0.675992006681295 1.0 0.9768151811526568 14 P60953,Q96N67,Q14204,Q9UH99,Q9Y613 5 +Appendage development 0.4226269459737215 0.4158991615672031 0.6774837930651456 1.0 0.978537750213537 18 O75569,Q15648,O75592,Q9C0E8,Q9P2D1 5 +Notch signaling pathway 0.4170111507252367 0.4153345870536134 0.6778969850409493 1.0 0.9788394557926968 16 Q15334,P49407,Q00534 3 +Regulation of hematopoietic progenitor cell differentiation 0.4011952670703149 0.414939321907663 0.678186323196285 1.0 0.9789028935613928 11 Q00534 1 +Fibroblast proliferation 0.422299368096713 0.4145814596752473 0.6784483229696481 1.0 0.9790646517108956 18 P49917,P14174,Q5TBB1,P20248,P21359,P14635,Q7Z5K2,Q00534,P11802 9 +Negative regulation of tor signaling 0.3936747954866521 0.4132335873563596 0.679435482278619 1.0 0.9792670827601028 9 Q13315 1 +Response to nitrogen compound 0.1948550525292361 0.4131959997754871 0.6794630186882178 1.0 0.9792670827601028 242 P00374,P17655,P49841,P00492,P07741,O15357,P43490,O75116,Q8IZH2,Q9BY42,P46109,Q08209,O00410,P54132,P09874,P31751,Q00535,Q8TBX8,Q13144,P26358,Q9P2J5,Q7L576,Q9UER7,P49721,P17612,P07814,Q5VYK3,Q7L5D6,O60610,P20248,Q6NTF9,P49770,P40763,P61586,Q96RD7,P63151,P78527,Q92499,Q9GZT9,Q92908,Q99741,O14654,Q06124,P55212,P42574,P42345,P50570,O00443,P50747,Q8IXJ6,P11802,O14744,Q9P0V3,Q9UQB8,Q14258,P27695,Q13464,Q06787,P28482,Q8TAT6,Q99707,Q6PKG0,Q92974,Q99996,P46821,Q9Y5X3,P04818 67 +Mapk cascade 0.2493387047180754 0.4129457866788593 0.6796463340219461 1.0 0.9792670827601028 98 P36507,O75116,P46109,Q92905,P21359,P49327,Q9UER7,Q9Y5V3,P18615,P14174,P51452,Q99956,P20248,Q99873,Q06124,Q96P70,P49407,O60271,O14744,P31689,O75832,P47897,Q16512,P09429,Q13464,P28482,P29372,P30046,P60953,P46940,Q14152,P04035 32 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4006525002059899 0.4127712477038787 0.6797742189215741 1.0 0.9792670827601028 11 O96017,Q96RU2,P61254,P14174 4 +Endosome to lysosome transport 0.4160224035523571 0.4113756067309785 0.6807971377260389 1.0 0.9797798950578654 16 Q9H269,O14617,P20645,Q9UGU5 4 +Negative regulation of leukocyte proliferation 0.3967917510520236 0.4112906143275772 0.680859450912491 1.0 0.9797798950578654 10 Q16512,Q13315,P42574 3 +Neuronal action potential 0.3773875207718259 0.4111053363355455 0.6809952972146611 1.0 0.9797798950578654 5 P42345 1 +Lipopolysaccharide mediated signaling pathway 0.3929653693263194 0.4104046291562687 0.6815091510631759 1.0 0.9802323252076076 9 Q9UDY8,P28482 2 +Intraciliary transport 0.3848194674186369 0.4080334231923004 0.6832491369773739 1.0 0.9823022598992188 7 Q9BW83,P36405,Q8NCM8,Q9UIS9 4 +Negative regulation of i kappab kinase nf kappab signaling 0.3954932244103413 0.4061308443039365 0.6846464636131517 1.0 0.9832288118306314 10 O60826,P61586,Q6GQQ9 3 +Glucose catabolic process 0.3988316564122148 0.4055333790914326 0.6850854879479358 1.0 0.9835401479816 11 P85037,P17858 2 +Positive regulation of nuclear division 0.405243595533861 0.4046510960221777 0.6857339942388945 1.0 0.9839250675411956 13 O14965,Q15398,Q9UJX5,Q14674,Q8IXJ6 5 +Microtubule polymerization or depolymerization 0.448592285720214 0.4037087782800453 0.6864268836656984 1.0 0.98427043266074 43 O43670,Q13526,O15344,Q9BSJ2,O00139,Q99661,Q14203,Q15058,Q15555,P04350,Q8WWK9,Q96P70,Q9P1Y5,Q9Y295,Q96CW5,Q14155,Q16512,P78559,Q14008,P29372,Q96S59,Q92974,Q99996,Q7Z460,P46821,Q9BTW9,Q66K74 27 +Cellular response to camp 0.3795852325585158 0.4029156967296932 0.6870102435534471 1.0 0.9848906455332622 6 P27695 1 +Dna catabolic process endonucleolytic 0.3795305894542874 0.4026993220831933 0.6871694326975315 1.0 0.9849026329049344 6 P27695 1 +Macroautophagy 0.219300779902413 0.4014794595565861 0.6880671579841025 1.0 0.9859729079737084 102 O14681,Q96EP0,Q9Y263,O95352,Q00535,P42858,Q9H269,Q9NT62,Q7Z6Z7,P42345,P42574,Q8WUX9,Q13501,Q9Y4P1,P50851,Q6PKG0,Q15042,Q99570,Q8NCE2,Q99816 20 +Integrin mediated signaling pathway 0.4158400611216672 0.399531430347392 0.6895016695347487 1.0 0.9873784872942782 17 Q06124,P22392,Q14185,P35579,P60953,Q9P258,Q13418 7 +Cellular glucan metabolic process 0.4154400123684135 0.3979527057882365 0.6906650479761034 1.0 0.988269908525901 17 P49841,P06737,P31751,P62136,Q15185,P46976,P35573,P08237,P11216,P13807 10 +Developmental growth 0.2073640286332895 0.3959960485783693 0.6921079432428576 1.0 0.988870262746058 116 Q15648,Q9BRT6,Q9Y263,Q93008,Q7Z4V5,Q00535,Q9P2D1,Q9HCL2,Q9HCM4,O14965,Q9UPN3,Q99956,P40763,Q96F07,P18074,Q14353,Q92908,Q06124,P42345,P50570,Q13315,O60271,P46940,Q9P265,P46821,P04818 26 +Regulation of leukocyte differentiation 0.4389755189991219 0.393798904279434 0.6937295134449548 1.0 0.9894099166427404 29 P09429,O14617,P42345,O00203,P21359,Q00534,Q9UDY8,O43290,P78527,Q9Y3I1 10 +Pteridine containing compound metabolic process 0.4196030982394427 0.3936414462584301 0.6938457770124979 1.0 0.9894099166427404 19 P00374 1 +Regulation of chromatin assembly 0.4024368613948696 0.3936086484264441 0.6938699951230596 1.0 0.9894099166427404 13 P26358 1 +Negative regulation of signaling receptor activity 0.3722139367052755 0.3906271735654282 0.6960728368121971 1.0 0.9911899802269576 5 Q99816 1 +Protein adp ribosylation 0.3945186610414638 0.3886111036942456 0.6975638516317157 1.0 0.9917465602340744 11 P09874,Q7Z2W4,Q8IXJ6,P18085,P23381,Q9UGN5 6 +Regulation of neuron migration 0.3834053865495743 0.3874148862094531 0.6984490850113407 1.0 0.9919894617898516 8 Q96Q89,P40763,Q9Y263 3 +Defense response to other organism 0.2046143567439844 0.3873538503522835 0.6984942642128236 1.0 0.9919894617898516 168 Q96EP0,Q9UIV1,O95352,P40429,Q9BUI4,Q9HCL2,Q9UII4,P78362,P07814,P14174,Q01804,Q13309,Q96BN8,P78527,Q06124,Q9HCE1,P55212,Q8IXJ6,Q8IWZ3,O14802,Q9UDY8,Q96SB4,O15111,Q14258,P09429,Q9NW08,Q7Z7L1 27 +Positive regulation of heart growth 0.3752479829567436 0.3858971610379378 0.6995728332524145 1.0 0.9924420163237598 6 Q92908,Q9UGN5,Q16539 3 +Positive regulation of organ growth 0.3752479829567436 0.3858971610379378 0.6995728332524145 1.0 0.9924420163237598 6 Q92908,Q9UGN5,Q16539 3 +Prostate gland growth 0.3620895522388129 0.3855344795717267 0.6998414660120802 1.0 0.9926074659120078 3 Q05086,Q9NZJ7 2 +Regulation of reproductive process 0.4145916866509269 0.3841085147768174 0.7008980208019486 1.0 0.9936743542850032 18 O14965,P30307,P35579,Q8IY37,Q8IXJ6 5 +Regulation of actin cytoskeleton reorganization 0.3860401813244151 0.3832306798429109 0.7015487320637752 1.0 0.9939027224796386 9 Q9UQB8,Q00535,Q9Y5K6 3 +Regulation of protein depolymerization 0.4387902751825153 0.3830699158492534 0.7016679250583666 1.0 0.9939027224796386 31 P78559,P29372,P35241,Q9P1Y5,Q92974,Q7Z460,P47755,Q9UHB6,P46821,Q9BPX3,Q66K74 11 +Regulation of lamellipodium assembly 0.4084585379342639 0.3816417837810947 0.7027270869437392 1.0 0.9950608402096424 16 P47756,P61160,P42345,P60953,P50570,Q6IBS0,Q9Y2A7,Q7L576,Q8WUW1 9 +Regulation of neuronal synaptic plasticity 0.38560660987568 0.3815565876311702 0.7027902902062588 1.0 0.9950608402096424 9 Q15334,Q15042,P21359 3 +Heparan sulfate proteoglycan biosynthetic process 0.3738079415032275 0.3803176753991958 0.7037096164747632 1.0 0.9957716255844252 6 Q99805 1 +Heparan sulfate proteoglycan metabolic process 0.3738079415032275 0.3803176753991958 0.7037096164747632 1.0 0.9957716255844252 6 Q99805 1 +Protein localization to nuclear body 0.3957359070998801 0.380263565459936 0.7037497782652562 1.0 0.9957716255844252 12 Q7L2J0 1 +Negative regulation of schwann cell proliferation 0.3560131304088333 0.3796623118084982 0.7041960997952621 1.0 0.9958119021295314 2 Q9UPY3 1 +Schwann cell proliferation 0.3560131304088333 0.3796623118084982 0.7041960997952621 1.0 0.9958119021295314 2 Q9UPY3 1 +Peripheral nervous system development 0.3988278241650851 0.3796089216384999 0.7042357372180974 1.0 0.9958119021295314 13 P31751,P21359,Q8IXJ6,Q8TEW0,Q00535 5 +Insulin metabolic process 0.3548194568785443 0.3750267311144296 0.7076405865520647 1.0 0.9995493404339184 2 P14735 1 +Negative regulation of vasculature development 0.4007167481193685 0.374774252327866 0.7078283646033827 1.0 0.9995493404339184 14 O75116 1 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4341210335525501 0.3743967645515447 0.7081091497230876 1.0 0.9995493404339184 29 Q5TAX3,Q86TB9,P67809,A5YKK6,Q9Y2L1,Q96C86 6 +Chemokine production 0.380013626013338 0.3743341460208372 0.7081557308357898 1.0 0.9995493404339184 8 P09429 1 +Regulation of mirna transcription 0.3799782355507124 0.3741987182696575 0.7082564775172651 1.0 0.9995493404339184 8 Q92908,P40763,P51532 3 +Somite development 0.3898768344406034 0.3707571782762158 0.7108183984848551 1.0 1.0 11 Q9HCM4,P78527 2 +Ribonucleoside monophosphate catabolic process 0.3624962675425398 0.3698363780177393 0.7115044082777868 1.0 1.0 4 P00492,P49902,P00813 3 +Purine nucleoside monophosphate catabolic process 0.3624962675425398 0.3698363780177393 0.7115044082777868 1.0 1.0 4 P00492,P49902,P00813 3 +Chloride transmembrane transport 0.3788170772859514 0.3697676269995832 0.7115556381822268 1.0 1.0 8 Q9Y666 1 +Establishment of planar polarity of embryonic epithelium 0.3579104477612035 0.3693475061214492 0.7118687200511691 1.0 1.0 3 O95487,P43034 2 +3 phosphoadenosine 5 phosphosulfate biosynthetic process 0.3533273649656836 0.3692676650895942 0.7119282245640663 1.0 1.0 2 O43252 1 +Thymus development 0.3823325939544804 0.3690214473378078 0.7121117385913887 1.0 1.0 9 O95067,Q13315 2 +Calcineurin mediated signaling 0.3703023608255253 0.3668867082648626 0.7137035264225113 1.0 1.0 6 P49841,Q08209,P42345 3 +Negative regulation of erad pathway 0.3570149253731424 0.365919038342232 0.7144254895884625 1.0 1.0 3 O43765,Q04323 2 +Organelle inheritance 0.3848300058979692 0.3648452133387083 0.7152269526462025 1.0 1.0 10 Q99986,Q13190,Q92538,P28482 4 +Regulation of glucose import 0.3810501651028509 0.364163296353158 0.7157360732255162 1.0 1.0 9 P31751 1 +Axon development 0.3481985338592727 0.3633427856728682 0.7163488357198833 1.0 1.0 80 P00374,Q93008,Q00535,Q9UPN3,P83731,Q06124,P42574,P50570,Q8TEW0,Q96N67,Q7KZI7,Q9UQB8,Q16512,P78559,O75592,Q99707,Q9P265,P46821,Q15334,Q9BPU6,Q66K74 21 +Positive regulation of mirna transcription 0.3649166231654592 0.362522185305094 0.7169618479314128 1.0 1.0 5 P51532 1 +T cell differentiation in thymus 0.3873528770337572 0.361209775468007 0.7179426350069829 1.0 1.0 11 P62753,Q00534 2 +Amyloid precursor protein metabolic process 0.4159092376279366 0.3607560230953108 0.7182818404423121 1.0 1.0 21 P42574,O75116,Q96P70,P27695 4 +Regulation of osteoblast differentiation 0.3869079120031653 0.3595385438134438 0.7191922489411255 1.0 1.0 11 Q13418,Q00534,P17612,P20248 4 +Regulation of protein targeting to membrane 0.3759477932025572 0.3589214304536559 0.7196538672028046 1.0 1.0 8 Q00535,Q12955,Q9UHD1,P31751 4 +Sensory perception of light stimulus 0.4128626034611721 0.3581494915095718 0.7202314433245471 1.0 1.0 20 O75569,Q3SYG4,Q00169 3 +Negative regulation of axonogenesis 0.3637347526300945 0.3580592490613055 0.720298974489548 1.0 1.0 5 Q00535 1 +Mitotic g2 m transition checkpoint 0.4075923259547954 0.3573532072399948 0.7208274023139689 1.0 1.0 18 O60921,Q92547,Q68E01,P54132,P53350,Q13315,Q13564 7 +Regulation of chromatin organization 0.4044211284882038 0.3555862477159181 0.722150444123886 1.0 1.0 17 Q9UPP1,Q66K74,P26358,Q08945 4 +Nucleoside monophosphate catabolic process 0.3626045400238861 0.3538151389652247 0.7234774272048925 1.0 1.0 5 P00492,P00813,P49902,O43598 4 +Negative regulation of leukocyte migration 0.3705521471181061 0.3530255100697365 0.7240693159841014 1.0 1.0 7 P14174,P30046 2 +Meiotic sister chromatid cohesion centromeric 0.3530310544105352 0.3508428634357036 0.7257062382806585 1.0 1.0 3 O43683 1 +Nucleic acid phosphodiester bond hydrolysis 0.269259166758661 0.349834519760012 0.7264628909700019 1.0 1.0 94 Q2NL82,P27695,Q07864,Q8IZH2,O75818,A5YKK6,P78316,Q99575,O15091,Q9Y2L1,Q9GZR2,Q9H9L3,P28340,Q96C86,Q96DE0,P18074 16 +Viral translation 0.3967611300341781 0.3484453392158212 0.7275057575707939 1.0 1.0 15 Q9ULC4,Q14152,O15371,P41214 4 +Regulation of erbb signaling pathway 0.3837538410234221 0.3477963608197261 0.7279931228963417 1.0 1.0 11 P27695,P22681,P51452,Q92600,Q99816 5 +Water soluble vitamin metabolic process 0.4188350545886052 0.3476550192600988 0.728099281202957 1.0 1.0 24 P00374 1 +Negative regulation of stress activated protein kinase signaling cascade 0.3801739925198577 0.3474510268543532 0.7282525042770771 1.0 1.0 10 P47897,P51452,P31689,P78318,P43034 5 +Embryonic placenta development 0.3960749501262843 0.3459100673264957 0.7294103025394683 1.0 1.0 15 Q12830,Q15648,P28482,P20248,Q9ULT8,Q9NR09 6 +Inflammatory cell apoptotic process 0.3643945626128262 0.3447515997417399 0.7302811225154779 1.0 1.0 6 P42771 1 +Transcription initiation from rna polymerase ii promoter 0.4216755615550441 0.3444100678078496 0.730537918478884 1.0 1.0 26 Q86VP6,Q15648,P09429,Q9ULK4,Q14241,Q9Y6J9,O60244,Q9Y2X0,Q15369 9 +Organic cyclic compound catabolic process 0.1983490614168669 0.3441745511378602 0.7307150197539762 1.0 1.0 178 P67809,O75116,Q8IZH2,Q86W50,A5YKK6,Q13126,Q96DE0,Q96HR8,Q5TAX3,Q9Y2L1,Q9HCE1,Q86TB9,Q99575,Q9GZR2,Q13315,O00154,Q15477,Q9Y2V2,P27695,Q14147,Q6PKG0,Q96C86,Q9BPU6,Q6P6C2 24 +Viral rna genome replication 0.3952788569729434 0.3429798432529404 0.7316136241928635 1.0 1.0 15 P42356,P60953,Q06787,O75116 4 +Cytokine production involved in inflammatory response 0.3677137145168743 0.3425151611028871 0.7319632363221307 1.0 1.0 7 Q9BWS9,Q53EL6,P40763,Q16539 4 +Natural killer cell activation 0.3715196701704855 0.3424771666371862 0.731991824616488 1.0 1.0 8 Q14790,P46379,P31146,Q9ULT8 4 +Positive regulation of neuron migration 0.3634483493233907 0.3412660993898725 0.7329032664326955 1.0 1.0 6 Q96Q89,Q9Y263 2 +Regulation of mitochondrial mrna stability 0.3547327560465803 0.340653296432603 0.7333646018293303 1.0 1.0 4 Q6L8Q7,Q9NYY8,Q7L8L6 3 +Regulation of protein localization to cilium 0.3544341594505803 0.3395531407325177 0.7341930717226413 1.0 1.0 4 Q10713,P49841,P50395 3 +Morphogenesis of a polarized epithelium 0.3939500159667712 0.3381155509506797 0.735276112005381 1.0 1.0 15 P60953,Q9P1Y5,P61586,P43034 4 +Regulation of translational elongation 0.3625693239567764 0.3380431431684648 0.7353306759662503 1.0 1.0 6 Q9H2P9,P63241 2 +Trophectodermal cell differentiation 0.3616349382838569 0.3346332013486765 0.7379017963840044 1.0 1.0 6 A5YKK6,Q13618 2 +Regulation of protein serine threonine kinase activity 0.3930818221272208 0.3340418647957692 0.7383479677737712 1.0 1.0 67 P36507,P42771,P21359,P54132,O75909,Q9UII4,Q9Y5V3,P14174,P42858,P20248,Q9NYV4,P61586,Q9Y3I1,P30307,P42574,P14635,P31689,O75832,Q16512,O95067,P46940,P53350,P04035,O95373,O00410,Q99816 26 +Cardiac chamber morphogenesis 0.386633314574364 0.3340406586612998 0.7383488779085858 1.0 1.0 13 Q9P2D1,Q15648,P62942,P20248 4 +Magnesium ion homeostasis 0.3483582089552275 0.3335342665044558 0.7387310278259378 1.0 1.0 3 Q6P4Q7,Q12955 2 +Ovarian follicle development 0.3652319333730456 0.3334489330014062 0.7387954312930112 1.0 1.0 7 P49770,Q13144,Q13315 3 +Scarna localization to cajal body 0.35663082437274 0.3317765951642702 0.7400579585457439 1.0 1.0 5 Q9BUR4,P50991,O60832,P17987 4 +Skin epidermis development 0.389045919402797 0.3313600260904114 0.7403725554530662 1.0 1.0 14 Q92908,O00203,P21359,Q5C9Z4,P18074 5 +Protein localization to nucleoplasm 0.3858450851039612 0.3311909323063017 0.7405002690740525 1.0 1.0 13 Q7L2J0 1 +Protein localization to axon 0.3475741721161109 0.3306706911747639 0.7408932430751931 1.0 1.0 3 O14579 1 +Positive regulation of erbb signaling pathway 0.3602644963556522 0.3296619480015359 0.7416554089094667 1.0 1.0 6 P27695,P22681 2 +Telomere organization 0.3857006980705674 0.3286280530182215 0.7424368414911853 1.0 1.0 69 O60921,P27695,P28482,Q8IZH2,P35244,Q8IXJ6,P35251,Q9UBB9,Q13535,Q13315,P78527,Q96HR8 12 +Deoxyribonucleotide biosynthetic process 0.3638813169926853 0.3285641244421687 0.7424851683463374 1.0 1.0 7 P04818,P23921 2 +Histone h2a monoubiquitination 0.3555232348334622 0.327764577570853 0.7430896720877433 1.0 1.0 5 Q6W2J9 1 +Epithelium development 0.1960206571990268 0.3277432793491159 0.7431057769448677 1.0 1.0 181 Q9UM54,Q15648,P49841,O75116,P31751,Q92990,P21359,P49327,Q9UPY5,Q9P2D1,Q9Y5V3,Q9HCM4,P17612,P25440,P62081,P35241,P20248,Q00534,P67870,P78527,P18074,Q92908,P55212,P42574,O00203,P42345,Q8NHU6,Q9P1Y5,P55196,Q96Q89,Q13315,Q9ULT8,Q16512,P22392,Q13464,P28482,P60953,P46940,Q7Z460,P46821,P04818,Q99816 42 +Negative regulation of histone modification 0.404596068025699 0.3276092122371721 0.7432071556738331 1.0 1.0 20 P29375,O95071,Q6W2J9,P26358 4 +Regulation of cell aging 0.387939498592394 0.3273777704699742 0.7433821775457026 1.0 1.0 14 P67809 1 +Single stranded viral rna replication via double stranded dna intermediate 0.3594263519569715 0.3266393171661395 0.7439407024461784 1.0 1.0 6 P11388,Q9UK61,Q9Y6X9,Q02880,Q15047 5 +De novo pyrimidine nucleobase biosynthetic process 0.3549973793048783 0.3258680361729932 0.7445242002304728 1.0 1.0 5 P27708 1 +Mitotic g2 dna damage checkpoint signaling 0.3843048441138297 0.3256570361888944 0.7446838537698985 1.0 1.0 13 Q92547,Q13315 2 +Positive regulation of chromosome separation 0.3740286143400616 0.325112308664338 0.7450960735930818 1.0 1.0 10 Q9UJX5,Q14674,Q15398 3 +Negative regulation of programmed necrotic cell death 0.3547109733569593 0.3248373369907451 0.7453041847643243 1.0 1.0 5 Q13546,Q14790,Q92974 3 +Negative regulation of necrotic cell death 0.3547109733569593 0.3248373369907451 0.7453041847643243 1.0 1.0 5 Q13546,Q14790,Q92974 3 +Negative regulation of stem cell differentiation 0.3666476448676117 0.3248092168288933 0.745325468440228 1.0 1.0 8 P40763,Q9NYV4 2 +Positive regulation of ossification 0.3589084058084605 0.3247781942641057 0.7453489491214595 1.0 1.0 6 Q06124 1 +Rna destabilization 0.4285936254640714 0.3229562260202482 0.7467283936575408 1.0 1.0 45 Q9HCE1,Q5TAX3,Q86TB9,P67809,O75116,Q86W50,Q9Y2L1,Q96C86 8 +Golgi to plasma membrane transport 0.413484683163512 0.3208686337651126 0.748309944717737 1.0 1.0 25 Q96KP1,O60826,Q9UPN3,P50570,O15027,Q8TAG9,Q4J6C6,Q15334,P63244,Q9Y6D5 10 +Positive regulation of dna binding 0.3948625794219638 0.3206688947365096 0.7484613218069425 1.0 1.0 17 Q8IXJ6,P15531,P09429,P18074 4 +Bergmann glial cell differentiation 0.3534218296196078 0.3202177635388938 0.7488032582487605 1.0 1.0 5 P28482 1 +Regulation of integrin activation 0.3445372519676061 0.3196910007277783 0.7492025824442896 1.0 1.0 3 Q15058 1 +Purine nucleobase metabolic process 0.3758152110535584 0.3190707635253595 0.7496728531734911 1.0 1.0 11 P00492,P07741,Q9P2T1,P49915 4 +Negative regulation of glial cell proliferation 0.344179104477619 0.3184080214605388 0.750175454418748 1.0 1.0 3 Q9UPY3,Q96G23 2 +Protein polyubiquitination 0.4186517749301677 0.3171151878034458 0.7511562009887331 1.0 1.0 54 Q96EP0,Q13616,Q96JP5,Q9Y263,P49427,Q7Z6Z7,P22681,Q13309,P52888,O95071,Q9ULT8,Q96FW1,Q15386 13 +Cell adhesion mediated by integrin 0.3522243095976605 0.3159555953687574 0.752036212635929 1.0 1.0 5 Q06124 1 +Glial cell differentiation 0.4274157505112546 0.3157991049094019 0.7521549975534303 1.0 1.0 40 Q06124,P28482,P42345,P31751,P21359,Q8TEW0,P49770,Q13144,Q00535,P40763,P61586,Q8IXJ6,Q00534,O14744,Q96P11,P18074,Q13418 17 +Hematopoietic stem cell differentiation 0.377623299065147 0.3135475333615979 0.7538647135045229 1.0 1.0 12 P78527,Q00534 2 +Mucopolysaccharide metabolic process 0.3633298750042613 0.3130395569871453 0.7542506092156176 1.0 1.0 8 Q8NCH0,O43505,O60701,Q00610 4 +Dna methylation or demethylation 0.4092766137059127 0.3126980180469583 0.7545101014828082 1.0 1.0 24 Q9NRZ9,P27695,P09874,Q93008,Q01804,Q9UIF9,Q8NB78,P26358,O14744 9 +Histone h2a acetylation 0.3702322082300169 0.3116758821988339 0.7552868587839898 1.0 1.0 10 Q9Y4A5 1 +Regulation of translational fidelity 0.3863140823901882 0.3108280680640437 0.755931330641231 1.0 1.0 15 P46782,Q9BTE6,P41252,Q9P2J5,P26640 5 +Artery morphogenesis 0.3588051492278519 0.3105208609034151 0.756164898264587 1.0 1.0 7 P21359 1 +Positive regulation of protein localization 0.2022776993029753 0.3104930449210957 0.7561860476769848 1.0 1.0 142 Q96EP0,P09874,O75116,P30419,P31751,O95071,Q4G0J3,Q96D46,Q9Y6B6,Q7Z6Z7,Q92614,Q96Q89,P19784,Q13501,Q7L2J0,P78559,P53350,P08237,Q15334,Q99816 20 +Regulation of glial cell differentiation 0.3732617345107603 0.310090765579671 0.7564919343961172 1.0 1.0 11 Q15382,P42345,Q9UPY3,P21359,O14744 5 +Response to gonadotropin 0.3505092701519106 0.3099007067087342 0.7566364653703284 1.0 1.0 5 P20248 1 +Cellular response to gonadotropin stimulus 0.3505092701519106 0.3099007067087342 0.7566364653703284 1.0 1.0 5 P20248 1 +Regulation of microtubule cytoskeleton organization 0.4116929615377806 0.3083335597758213 0.7578285321374536 1.0 1.0 57 P49841,Q14203,Q8NI35,Q14204,P61586,P04350,Q8WWK9,Q8WUX9,Q9P1Y5,Q00610,Q9Y295,Q7KZI7,Q14155,Q16512,P78559,Q14008,Q13464,P29372,Q92974,Q99996,Q7Z460,P53350,P46821,Q9BTW9,Q66K74 25 +Regulation of transcription elongation from rna polymerase ii promoter 0.3988495686059072 0.3071766322643474 0.7587089310111963 1.0 1.0 20 P18615,Q9Y5B9,Q8IXH7,O75909,Q9NYV4,Q4G0J3,Q9H3P2,Q14004 8 +Positive regulation of dephosphorylation 0.381266878498629 0.3038720510254697 0.7612253715869106 1.0 1.0 14 P63167,Q69YH5,Q13464,P42345,Q15257,Q14738 6 +Coenzyme a metabolic process 0.3676962109947145 0.30285911923652 0.7619972271481754 1.0 1.0 10 Q8WVC6,P53396,O00154,P04035 4 +Embryonic appendage morphogenesis 0.3742704921408573 0.3018895595707492 0.7627362549246559 1.0 1.0 12 Q9P2D1,Q9C0E8 2 +Auditory receptor cell morphogenesis 0.3433860853986281 0.3000598041047972 0.7641315389175647 1.0 1.0 4 Q14160,Q14651,O95487 3 +Renal system process 0.3667861542937282 0.2997266225097832 0.7643856898582451 1.0 1.0 10 Q16512,Q9Y5X3,Q9UNF1,P17612 4 +Protein k63 linked deubiquitination 0.3765864431941615 0.2986296906428609 0.7652226087538023 1.0 1.0 13 Q6GQQ9,Q01804 2 +Protein maturation by protein folding 0.351423210181282 0.298469835830781 0.7653445950417561 1.0 1.0 6 P62942 1 +Anoikis 0.3590297553030566 0.2981091438296516 0.7656198629249555 1.0 1.0 8 O96017 1 +Lung morphogenesis 0.3626473313742117 0.2978411124493972 0.7658244345421061 1.0 1.0 9 O00203,P28482 2 +Dendritic spine maintenance 0.3382948350872693 0.2976948746593658 0.7659360556033776 1.0 1.0 3 Q13614 1 +Actin filament organization 0.1962948315172906 0.2963299548115907 0.7669781120326726 1.0 1.0 107 Q9UM54,O43795,P31146,O15357,O75116,Q9Y2A7,P57737,Q7L576,Q9Y5K6,P35241,O60610,Q13045,Q96F07,Q8WUW1,O94832,P42345,P49407,P47755,Q9Y613,Q9UQB8,Q9BPX3,Q16512,P63167,Q13464,P60953,Q92974,Q7Z460,Q9UHB6,O00401,Q13618 30 +T cell apoptotic process 0.3724966464485583 0.295813351894034 0.7673726257667282 1.0 1.0 12 Q9HCL2,P62753 2 +Negative regulation of g protein coupled receptor signaling pathway 0.3543896848338618 0.295241098501621 0.7678097084358961 1.0 1.0 7 P49407 1 +Animal organ formation 0.3543344598505576 0.2950524838173165 0.7679537870466333 1.0 1.0 7 P28482 1 +Negative regulation of dna repair 0.3783074191613299 0.2937329807098401 0.7689619504597447 1.0 1.0 14 Q15554,O95071,Q9UBB9,Q96FW1,Q9BRJ7 5 +Viral translational termination reinitiation 0.3499637955086861 0.2934710498488669 0.7691621246927991 1.0 1.0 6 Q14152,O15371 2 +Cilium organization 0.4114325987535882 0.2932644164686417 0.7693200500415749 1.0 1.0 55 P49841,Q3SYG4,Q01968,P18085,Q86Y56,Q14203,Q9Y5K8,P61160,P42858,P10155,Q9Y496,Q9NT62,Q9H4M9,Q8TC07,Q9BZH6,P50570,P63167,P57076,P27695,Q15019,Q9H223,Q92538 22 +Positive regulation of leukocyte proliferation 0.3840980877492846 0.293061262535799 0.7694753254551747 1.0 1.0 16 P09429,Q96QE3,P28482,P14174,Q9HCL2 5 +Regulation of chromosome segregation 0.4197308609410299 0.2923073065468014 0.7700516728395417 1.0 1.0 47 Q15398,P68400,O43670,Q9P258,Q99661,Q69YH5,P50748,Q969U7,Q9UJX5,Q8IXJ6,P19784,P14635,Q5JVF3,Q13315,Q14674,Q9H900,Q7Z5K2,P53350,Q13618 19 +Response to arsenite ion 0.3321396598030456 0.2919997558743499 0.7702868106248959 1.0 1.0 2 Q9H2U1 1 +Proteoglycan biosynthetic process 0.3571602898779834 0.2917344565242931 0.7704896621386652 1.0 1.0 8 Q8NCH0,Q8WVQ1,O60701,Q99805 4 +Proteoglycan metabolic process 0.3571602898779834 0.2917344565242931 0.7704896621386652 1.0 1.0 8 Q8NCH0,Q8WVQ1,O60701,Q99805 4 +Positive regulation of telomere maintenance via telomere lengthening 0.3941641080001512 0.2910184398032036 0.7710372166554118 1.0 1.0 20 Q13535,Q13315,Q96HR8 3 +Negative regulation of erbb signaling pathway 0.3526499568356582 0.2893291836358382 0.7723294815516015 1.0 1.0 7 P51452,P22681,Q99816 3 +Peptidyl serine dephosphorylation 0.3525884856981456 0.2891214279029184 0.7724884564050969 1.0 1.0 7 Q08209,P63151 2 +Chromosome separation 0.4198987671671873 0.2873725844018626 0.7738270507608744 1.0 1.0 43 Q969U7,Q15003,Q15398,P68400,P50748,Q9UJX5,O43670,Q14674,Q9H4L7,P19784,P14635,Q5JVF3,Q9H900,Q13315,P53350,Q6IBW4 16 +Regulation of receptor internalization 0.3732634526152323 0.2873638947162074 0.7738337036762455 1.0 1.0 13 Q15334,Q9UL63,P49407,Q13614 4 +Mononuclear cell differentiation 0.4177560548891235 0.2872560027191851 0.7739163083153784 1.0 1.0 48 Q15648,P49327,Q9P2D1,Q6IBW4,P40763,Q00534,O43290,P78527,Q9Y3I1,P49917,P42345,O00203,Q5JVF3,P62753,Q13315,Q9ULT8,Q9UDY8,P09429,O14617,P35579 20 +Regulation of dna metabolic process 0.2002346979247027 0.2872370098877285 0.7739308499368789 1.0 1.0 148 Q99504,Q8IZH2,Q93008,Q7Z4V5,P20585,O95071,Q13535,Q9Y4A5,Q96HR8,P52701,Q96L91,Q01804,Q9UBB9,P18074,P78527,Q9H4L7,Q13315,P09429,P28482 19 +Positive regulation of calcium ion transmembrane transport 0.3698140162554008 0.2867463064653475 0.7743065783022463 1.0 1.0 12 P42858 1 +Maintenance of cell polarity 0.3434886499402507 0.2857313812508554 0.7750838674996448 1.0 1.0 5 Q8WUM4,P49841,Q03001,O75083 4 +Inner ear receptor cell stereocilium organization 0.3434886499402503 0.285731381250854 0.7750838674996459 1.0 1.0 5 Q14160,Q14651,O95487,Q9BW83 4 +Auditory receptor cell development 0.3434886499402467 0.2857313812508418 0.7750838674996552 1.0 1.0 5 Q14160,Q14651,O95487,P43034 4 +Negative regulation of calcium ion transport 0.3512784990610086 0.2847125431047514 0.7758643801972405 1.0 1.0 7 P28161,Q06787,P21796,P62942 4 +Negative regulation of calcium ion transmembrane transport 0.3512784990610086 0.2847125431047514 0.7758643801972405 1.0 1.0 7 P28161,Q06787,P21796,P62942 4 +Axo dendritic transport 0.4080744581750224 0.2836928978827149 0.776645737890254 1.0 1.0 28 P78559,Q9NZ32,O14617,P27695,Q9Y496,Q14204,O60333 7 +Positive regulation of b cell activation 0.3709987537514799 0.2798167742491273 0.779618081595445 1.0 1.0 13 P14174,Q96FZ2,Q5JVF3 3 +Negative regulation of metaphase anaphase transition of cell cycle 0.3953574613032207 0.279268255765174 0.7800389657401947 1.0 1.0 22 P50748,O43670,P14635,Q5JVF3,Q13315,P53350 6 +Homeostasis of number of cells within a tissue 0.3361473008550201 0.2755154701624636 0.7829202420943302 1.0 1.0 4 Q06124 1 +Protoporphyrinogen ix biosynthetic process 0.3359139406642814 0.2747424195643811 0.7835141386523223 1.0 1.0 4 P50336 1 +Glucose import 0.3628042364205072 0.2746882720410007 0.783555742249026 1.0 1.0 11 P31751 1 +Bile acid biosynthetic process 0.3585012174649529 0.271989789815662 0.7856298700530127 1.0 1.0 10 Q9BZF3 1 +Cell junction organization 0.1982107973597022 0.2699869793018023 0.7871702707743702 1.0 1.0 124 O75116,P46109,Q13526,Q13614,P18085,Q00535,P07737,Q6DN90,Q9UPY5,Q7L576,O15258,Q9P258,Q14203,Q9HCM4,Q8NI35,Q9UPN3,P17612,P61160,P51452,P35241,P61586,Q15555,Q9H2G2,Q96QK1,Q9H8V3,Q05086,P55196,Q9P1Y5,Q8TEW0,Q16513,O60678,Q9UQB8,Q14155,P43034,P63167,Q13464,Q04637,P60953,Q15334,Q7Z460,P46821,Q9BTW9,O00401 43 +Regulation of lipid transport 0.3798673041897491 0.269585312314129 0.787479301193343 1.0 1.0 17 P07814,P14174,P31751,Q9BZF3,Q9Y6B6 5 +Regulation of autophagy 0.1996998000656482 0.2686093868086354 0.7882302880691103 1.0 1.0 103 Q96EP0,P49841,O95352,Q00535,Q8TBX8,Q9HAD4,Q9Y5K8,P17612,P42858,O75348,O75436,P40763,Q9Y3I1,P42345,P42574,O00443,O00429,Q8IXJ6,O43432,P19784,Q13315,Q9P0V3,Q05639,P09429,Q13464,Q04637,Q6PKG0,Q15042,P85037,Q99570,Q9Y5X3 31 +Regulation of voltage gated calcium channel activity 0.3381869787798333 0.2681547959288913 0.7885801686906346 1.0 1.0 5 Q00535 1 +Cellular response to oxygen containing compound 0.189261078468228 0.2681529462913893 0.788581592370641 1.0 1.0 212 P00374,Q15648,P17655,P49841,P07741,Q9Y263,P43490,O75116,Q8IZH2,P46109,Q13085,Q08209,P09874,P51532,P54132,P31751,Q00535,Q8TBX8,P26358,Q9P2J5,P17612,P07814,P14174,P20248,P22059,P40763,P78527,O14654,Q06124,Q9H8V3,P42345,P50570,O00443,Q8IXJ6,Q13315,P11802,Q9UDY8,Q9P0V3,O14744,Q9UQB8,O15111,O96017,P09429,P27695,Q13464,P28482,P40818,Q99707,Q6PKG0,Q92974,Q99996,P46821,Q9Y5X3,Q96C86,Q6P2Q9,O00410 56 +Regulation of mitotic nuclear division 0.4130575941573343 0.2655104392496896 0.7906162690056062 1.0 1.0 46 Q15398,O43670,O14965,Q69YH5,Q14999,P50748,Q969U7,P30307,Q9UJX5,Q96Q89,P14635,Q5JVF3,Q13315,O14744,P60953,Q14674,Q9H900,P53350,Q13618 19 +Regulation of calcium ion transmembrane transporter activity 0.3727263270129272 0.265193745991139 0.7908602124574542 1.0 1.0 15 P27695,Q06787,P42858,Q00535,P62942 5 +Protein polymerization 0.3439741377015514 0.2649607706101662 0.791039682527932 1.0 1.0 77 P31146,O43670,Q13526,Q9BSJ2,Q9Y2A7,P57737,Q7L576,Q14203,P35241,O60610,Q13045,Q96F07,P04350,P42345,Q96P70,Q9P1Y5,O00429,Q9Y295,Q96CW5,P47755,Q9UQB8,Q9BPX3,Q14155,Q16512,Q14008,Q99996,Q7Z460,P46821,Q9BTW9,O00401 30 +Response to vitamin 0.3664075435119016 0.2648474535385702 0.7911269791165281 1.0 1.0 13 Q15648,P50747,P46821,Q96C86,Q14258 5 +Female sex differentiation 0.3693717275867791 0.2642227509155345 0.7916082811279483 1.0 1.0 14 P42574,Q9P2D1,Q13315 3 +Positive regulation of bmp signaling pathway 0.3487556457053946 0.2639696231537133 0.7918033259903241 1.0 1.0 8 Q92908,P20248 2 +Interleukin 8 production 0.3692857464364951 0.2639470085510871 0.791820752062447 1.0 1.0 14 P09429,P49407,Q6GQQ9 3 +Microtubule polymerization 0.4076298261146757 0.2639082436509674 0.7918506232668376 1.0 1.0 32 Q14203,P04350,Q16512,Q14008,Q96P70,O43670,Q9P1Y5,Q9Y295,Q96CW5,Q99996,Q9BSJ2,Q7Z460,P46821,Q9BTW9,Q14155 15 +Chromosome organization involved in meiotic cell cycle 0.383322927080601 0.2634540638888818 0.7922006249051394 1.0 1.0 19 O95347,Q15003,Q15021,P46379,Q15645,Q9NTJ3,Q13315,Q9BXW9,Q6IBW4,O43683,P42695 11 +Positive regulation of filopodium assembly 0.3447595459450542 0.2633057179735059 0.7923149528440321 1.0 1.0 7 P60953,Q9H6U6,O00401,Q06787 4 +Regulation of myeloid leukocyte differentiation 0.3557518834937078 0.2631027813921404 0.7924713602110034 1.0 1.0 10 Q00534,P21359 2 +Trna catabolic process 0.3521151642451466 0.2629235808698967 0.7926094806559862 1.0 1.0 9 Q08J23,Q9BQ52,Q99575 3 +Regulation of gliogenesis 0.3655428361156089 0.2620783408859558 0.7932610447912014 1.0 1.0 13 Q8IXJ6,O14744,P21359,P42345 4 +Regulation of cell development 0.2638891781175598 0.2610643389987204 0.7940428916353046 1.0 1.0 93 P49841,Q14185,O75116,P46109,Q08209,P21359,Q00535,Q9P2D1,Q7L576,Q9P258,O14965,Q15058,Q9UPN3,Q14999,Q9UBS4,P63172,P78527,P49917,P42345,P50570,Q96N67,Q8IXJ6,O14744,Q9UQB8,Q14155,Q13418,P43034,P27695,Q13464,P60953,Q9P265,P46821 32 +Lymphocyte apoptotic process 0.3735051675141735 0.258273668757667 0.7961957063288063 1.0 1.0 16 P14174,Q9HCL2,P62753,P49327 4 +Facultative heterochromatin assembly 0.3781826633959235 0.2554391187453859 0.7983839602507732 1.0 1.0 18 Q9NRZ9,Q9UPP1,Q8IXJ6,Q9UIF9,P26358 5 +Regulation of tube size 0.3597473850732142 0.2540662400856076 0.7994443842813541 1.0 1.0 12 O75116 1 +Positive regulation of cell substrate adhesion 0.3974340335688562 0.2538602995146787 0.7996034866162729 1.0 1.0 27 Q9HCM4,P49841,Q13464,Q14185,P50570,P60953,P20248,Q00534,Q14155,Q13418 10 +Cerebellar cortex morphogenesis 0.3412713174676691 0.2522228988055365 0.8008687794296185 1.0 1.0 7 Q06124,Q00535 2 +Rna mediated gene silencing by inhibition of translation 0.3370245648966443 0.251094627149465 0.8017409497828987 1.0 1.0 6 P40763,P26196,Q04637 3 +Regulation of presynapse organization 0.324147704142687 0.2508364061622802 0.8019405931394048 1.0 1.0 3 Q04637 1 +Negative regulation of lymphocyte activation 0.37612089138106 0.2489771269121556 0.8033784744657706 1.0 1.0 18 P09429,P42574,P51452,Q13315,Q9Y3I1 5 +Maintenance of synapse structure 0.3277936074473986 0.248569923375774 0.803693476046593 1.0 1.0 4 Q15334 1 +Glial cell apoptotic process 0.3317518075924285 0.2476270998773515 0.8044229409612076 1.0 1.0 5 P42574 1 +Protein autoubiquitination 0.3667006153309535 0.2462106349096885 0.8055191834507984 1.0 1.0 15 P22681,Q13330,Q9ULT8,O94822,Q13618 5 +Cell cycle g1 s phase transition 0.3843253524891577 0.246141742999273 0.8055725106257252 1.0 1.0 63 Q9UPP1,Q13616,P23921,Q08209,P42771,Q00535,Q15058,P49427,P35241,Q13309,P20248,Q00534,P78527,Q9Y3I1,Q07864,P62753,Q13315,P11802,Q7L2J0,O96017,P27695,Q04637,P61254,P61289,Q7Z7L1,Q13618,O00743 27 +Positive regulation of syncytium formation by plasma membrane fusion 0.335408526595025 0.246054087733995 0.8056403632617481 1.0 1.0 6 Q14012,P17655,Q9H4M9 3 +Regulation of syncytium formation by plasma membrane fusion 0.335408526595025 0.246054087733995 0.8056403632617481 1.0 1.0 6 Q14012,P17655,Q9H4M9 3 +Establishment or maintenance of cell polarity 0.3710922988161008 0.2457977660308052 0.8058387864715038 1.0 1.0 68 P49841,O75116,P46109,P18085,Q99661,Q14203,Q8NI35,P61160,P42858,P61586,P63172,Q92796,Q9P1Y5,Q92614,Q8TEW0,Q9Y696,Q7KZI7,Q96Q89,Q96N67,Q13418,P43034,Q14008,Q13464,P35579,P60953,Q7Z460,Q92538,P53350,P46821,Q15334 30 +Positive regulation of lamellipodium organization 0.372220840005511 0.2453730943895824 0.8061675598847478 1.0 1.0 17 P42345,P60953,P50570,Q9Y2A7,Q7L576,Q8WUW1,Q14155 7 +Neuron cellular homeostasis 0.3389925334395147 0.2451254016566626 0.8063593351218032 1.0 1.0 7 P78559,Q00535 2 +Regulation of mrna binding 0.3389873544166681 0.2451094005788253 0.8063717243011954 1.0 1.0 7 Q06787,Q04637 2 +Centromeric sister chromatid cohesion 0.3309256107066654 0.2450569844623019 0.8064123089494339 1.0 1.0 5 Q9GZZ1,O43683 2 +Coenzyme a biosynthetic process 0.3350863678308979 0.2450560979093701 0.8064129953923884 1.0 1.0 6 Q8WVC6,O00154 2 +Negative regulation of nf kappab transcription factor activity 0.37730008730325 0.2444840288024863 0.8068559699085922 1.0 1.0 19 O60826,P49407,P42771,Q96BN8,O15111 5 +Cytoplasmic sequestering of protein 0.3532075692343293 0.2442215182061898 0.8070592624340234 1.0 1.0 11 O60826,Q9UNN5,Q7L5D6,O00221,O75832 5 +Regulation of phosphatidylinositol 3 kinase signaling 0.3458687663910913 0.2433280550159614 0.8077512726228488 1.0 1.0 9 Q12923,P22681 2 +Embryonic cleavage 0.3301471059975322 0.2426490094039123 0.808277311550277 1.0 1.0 5 P18074 1 +Signal transduction by p53 class mediator 0.4060731921095202 0.2425011770695617 0.808391844902244 1.0 1.0 47 Q9UM54,Q13535,O14965,P62081,P14174,P62841,P46087,P61927,P46777,Q96QE3,P55212,P42345,P60866,Q96RU2,Q13315,O75832,O96017,P61254,P63241 19 +Labyrinthine layer blood vessel development 0.3299395991522658 0.2420094375468142 0.8087728504636549 1.0 1.0 5 P28482 1 +Adherens junction organization 0.3620839397522553 0.2414198950103751 0.8092296947112696 1.0 1.0 14 P60953,Q9BTW9,Q9P1Y5 3 +Calcium ion transport into cytosol 0.3680597146064129 0.2413324840141723 0.8092974361783076 1.0 1.0 16 P27695,P17612,P31146,O60610,P42858,Q9P2D1,P62942 7 +Cardiac septum morphogenesis 0.3408440937412248 0.2392114324063979 0.8109416381959669 1.0 1.0 8 Q9P2D1,P20248 2 +Nucleoside phosphate catabolic process 0.3701354263006665 0.2389929112870898 0.8111110794676311 1.0 1.0 17 P00492,Q9Y3Z3,Q96DE0,O00154,Q9UKK9 5 +Rac protein signal transduction 0.3609183534283615 0.2378809318373335 0.8119734452396816 1.0 1.0 14 P50570,Q9Y2A7,Q8WUW1,P21359 4 +Negative regulation of nuclear division 0.3845327114174226 0.2376492361139618 0.8121531593839821 1.0 1.0 23 P50748,O43670,P14635,Q5JVF3,Q13315,P53350 6 +Detoxification 0.397457907384266 0.2350542664167934 0.8141666143729678 1.0 1.0 31 P00374 1 +Intrinsic apoptotic signaling pathway in response to dna damage 0.3854932498644176 0.2341799140245406 0.8148453077985853 1.0 1.0 24 O96017,P52701,P14174,P61254,Q96RU2,Q13315,P78527 7 +Cell morphogenesis involved in neuron differentiation 0.2356793525376238 0.2332601037439902 0.8155594367317769 1.0 1.0 97 P00492,P49841,Q93008,Q08209,Q00535,Q9UPN3,Q14999,P83731,Q06124,P50570,Q8TEW0,Q96N67,Q7KZI7,O60678,Q9UQB8,Q16512,P78559,O75592,P60953,Q15334,Q9P265,P46821,Q9BTW9,Q9BPU6,Q66K74,O00401 26 +Head development 0.195146400868182 0.2331045120640334 0.8156802512897958 1.0 1.0 154 O75569,Q9UPP1,Q8IY37,P21359,O43776,Q9P2D1,Q00534,Q96P11,P78527,P42574,Q96N67,Q8IXJ6,P19784,Q13315,Q9UQB8,Q9HCK8,P27695,P28482,Q15042,Q7Z460,Q9UID3,Q66K74,O15067 23 +Ncrna catabolic process 0.3889793860242501 0.232980652924773 0.8157764291483205 1.0 1.0 26 Q9Y2L1,Q8IZH2,Q96DE0,Q5TAX3 4 +Inositol phosphate mediated signaling 0.3349742062141582 0.2328884857507175 0.8158479996805081 1.0 1.0 7 P49841,Q08209,P42345 3 +Positive regulation of protein modification by small protein conjugation or removal 0.4039723648303305 0.2327848350923589 0.8159284893126066 1.0 1.0 45 O75925,O75592,P15880,Q9UBT2,P98170,Q7Z6Z7,Q13404,Q13618,Q96GX5,Q13526,Q13330,Q13309,O75832,P53350,Q15020,Q9UDY8,P62942,Q9NVI1 18 +Telomere maintenance 0.370716035026701 0.2323615122973037 0.8162572396128027 1.0 1.0 67 O60921,P27695,P28482,Q8IZH2,P35244,P35251,Q9UBB9,Q13535,Q13315,P78527,Q96HR8 11 +Embryonic morphogenesis 0.328760399568605 0.2300266288495246 0.8180710776408877 1.0 1.0 79 Q9UM54,O75569,Q15648,P67809,O75116,O60701,Q92990,Q9P2D1,Q9HCM4,P17612,P25440,P62081,P20248,Q9NPQ8,Q92908,P42574,Q16881,Q96Q89,P62753,Q9ULT8,P63167,Q13464,P28482,Q9C0E8,Q7Z460,Q9Y2X9 26 +Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.3259206510346801 0.2298114992328931 0.8182382487631603 1.0 1.0 5 P78316 1 +Regulation of b cell activation 0.374892992208218 0.2295340773131177 0.8184538376673465 1.0 1.0 20 Q16512,P14174,P42574,Q5JVF3,Q13315,Q96FZ2 6 +Rrna catabolic process 0.354567233681438 0.2283462501920845 0.8193770717016697 1.0 1.0 13 Q8IZH2 1 +Protein modification by small protein removal 0.3979368837001864 0.2277350978606483 0.8198521851438425 1.0 1.0 52 Q70CQ2,Q9UPT9,P40818,Q93008,Q9Y6J9,Q01804,Q96BN8,Q96RU2,Q15020,Q96FW1,Q9Y4A5,Q6GQQ9 12 +Dna geometric change 0.3942217457553614 0.2274087438010449 0.82010592181918 1.0 1.0 55 P17096,P09429,O14646,Q14839,P46063,P54132,Q9Y620,Q8N3C0,Q9H4L7,P38935,Q12873,Q86WJ1,Q9HCK8,Q9P2D1,P33993,P18074,Q92499,P33992 18 +Cell volume homeostasis 0.3366648308938864 0.2266887761759956 0.8206657552547221 1.0 1.0 8 Q9Y666 1 +Cellular response to toxic substance 0.3946675232577868 0.2264778303286262 0.8208298001434189 1.0 1.0 31 P00374 1 +Hindbrain morphogenesis 0.3438022442335469 0.2263803807593833 0.82090558576477 1.0 1.0 10 Q06124,P63167,Q00535 3 +Spliceosomal tri snrnp complex assembly 0.3437913372298011 0.2263483047921538 0.8209305313111577 1.0 1.0 10 Q15020,Q6P2Q9,Q9Y312,O43395 4 +Homologous chromosome segregation 0.3464018666309873 0.2238358295581516 0.8228850492697317 1.0 1.0 11 Q14674,Q13315 2 +Translational initiation 0.3655827852556828 0.2229175665012731 0.8235996642748311 1.0 1.0 68 P41567,P08708,P46782,Q92905,P40429,Q13144,Q9ULC4,O15371,P49770,Q9BY44,Q92499,P61247,P42345,Q7Z478,Q14240,P41214,Q06787,Q04637,Q6PKG0,O60841,Q14152 21 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.3234028229190441 0.2223545246948099 0.8240379097120492 1.0 1.0 5 P21359 1 +Ear morphogenesis 0.3587355937076113 0.2223474858643294 0.8240433887563825 1.0 1.0 15 O75569,P28482,Q9P2D1 3 +Cell cell signaling involved in cardiac conduction 0.3146268656716432 0.2217638355762828 0.8244977335000905 1.0 1.0 3 O75694,P78310 2 +Regulation of dendritic spine development 0.3582138602805173 0.2208340706212717 0.8252216339026777 1.0 1.0 15 Q9BRT6,Q06787,P61160,Q05086,Q9H2U1,Q9UQB8,P43034 7 +Positive regulation of dendritic spine development 0.3486405115918558 0.2205618339950875 0.8254336212284215 1.0 1.0 12 Q9BRT6,Q06787,P61160,Q9H2U1,Q9UQB8,P43034 6 +Camera type eye morphogenesis 0.3343166362928076 0.2198244310281657 0.8260078917787317 1.0 1.0 8 Q8NHU6 1 +Positive regulation of hydrolase activity 0.2518615274152707 0.2194437535709236 0.82630439008975 1.0 1.0 94 P49841,Q9Y263,O75116,P46109,Q13526,P31751,P21359,P49327,Q9HAD4,Q6DN90,Q9P2J5,Q9P258,Q9UKL3,Q14997,P20248,P40763,Q96F07,Q9H8V3,Q8TC07,P42345,Q15257,P55196,Q96N67,Q9UDY8,Q14155,P63167,P09429,Q13464,Q15042,P61289,Q86X10 31 +Response to ionizing radiation 0.3992111624724745 0.2172777666146043 0.8279918828895498 1.0 1.0 45 O60921,P49917,O96017,P22681,P09874,Q99504,Q92547,P42574,P50570,Q68E01,P61254,Q96RU2,Q13535,Q13315,P78527 15 +Protein localization to synapse 0.3405714731542326 0.2169962481901807 0.8282112687941443 1.0 1.0 10 Q9UQB8,P78559,Q15334 3 +Sulfur amino acid metabolic process 0.3537130912012201 0.2166783549902735 0.8284590174908524 1.0 1.0 14 Q13126 1 +Outflow tract morphogenesis 0.3363466080692143 0.2151128517073012 0.8296793342370563 1.0 1.0 9 Q92908,P60953,Q13418 3 +Regulation of mitotic sister chromatid segregation 0.3789280588715851 0.2147586257596819 0.829955512057744 1.0 1.0 24 P50748,O43670,P14635,Q5JVF3,Q13315,P53350 6 +Regulation of membrane depolarization 0.3324364723467982 0.2144181823014279 0.8302209639448064 1.0 1.0 8 P48506,P09874,Q8N335,Q12955,P48507,P30536,P63244 7 +Neuron migration 0.3808076348121498 0.2143824341025657 0.8302488387931066 1.0 1.0 25 Q9Y263,Q13885,Q93008,P46109,Q9H9T3,Q92974,Q7KZI7,Q00535,Q9BSJ2,P40763,Q96Q89,P46821 12 +Regulation of nuclear division 0.3971264449032496 0.2143735970188614 0.8302557295890858 1.0 1.0 48 Q15398,O43670,O14965,Q69YH5,Q14999,P50748,Q969U7,P30307,Q9UJX5,Q8IXJ6,Q96Q89,P14635,Q5JVF3,Q13315,O14744,P60953,Q14674,Q9H900,P53350,Q13618 20 +Positive regulation of posttranscriptional gene silencing 0.3588219878407175 0.214105096580165 0.830465101457043 1.0 1.0 16 Q06787,Q04637,Q9HAV4,P26196,P40763 5 +Regulation of stress activated protein kinase signaling cascade 0.3855347214955299 0.212457403599121 0.8317502061778037 1.0 1.0 28 P47897,P36507,P09429,P98170,P28482,P29372,P51452,P60953,Q92905,O15344,P49327,P31689,Q99873,P43034 14 +Regulation of protein tyrosine kinase activity 0.3423242358677282 0.212119407123513 0.8320138795017207 1.0 1.0 11 P22681,Q13432,Q86XI2,Q15334,Q92796,Q99816 6 +Positive regulation of actin filament polymerization 0.342308690592846 0.2120754620425436 0.8320481627443232 1.0 1.0 11 Q9UQB8,Q9Y2A7,P61586,P42345 4 +Regulation of protein deubiquitination 0.3315821925173041 0.2119883404454778 0.832116130587151 1.0 1.0 8 Q01804 1 +Positive regulation of protein dephosphorylation 0.3488616818706795 0.2118707647226863 0.8322078591813957 1.0 1.0 13 P63167,Q69YH5,P42345,Q15257,Q14738 5 +Cell cell signaling 0.18676996579602 0.2112021420706813 0.8327295393243814 1.0 1.0 191 Q70CQ2,P49841,P68400,P43490,P46109,Q08209,Q13526,Q13614,P51532,P62136,O95071,Q00535,P21359,Q4J6C6,Q9UPY5,Q9Y666,Q7L576,Q9P2D1,Q9UPN3,P17612,P14174,P22059,Q96BN8,Q96RD7,P53985,P67870,Q06124,P55196,Q15418,Q9UBB6,Q7KZI7,P19784,Q9UQB8,Q13501,P17858,Q9HCK8,Q13418,P78559,O60333,P27695,Q06787,P28482,Q13555,P60953,P40818,Q15042,Q9UGU5,Q99996,P46821,P08237,Q15334,Q13618 52 +Positive regulation of mitotic nuclear division 0.3453317456138329 0.211114777197499 0.8327977095566605 1.0 1.0 12 Q9UJX5,O14965,Q14674,Q15398 4 +Central nervous system development 0.1865912066034441 0.2090122127437238 0.8344387047836397 1.0 1.0 187 O75569,Q15648,P49841,P00492,Q9UPP1,Q8IY37,P46109,Q08209,P21359,Q00535,Q9BSJ2,O43776,Q9Y2A7,Q13144,Q9UPY5,Q9P2D1,Q14203,Q9H0D6,P12277,P49770,P40763,Q00534,Q96P11,P78527,P18074,Q06124,P49917,P42345,P42574,Q9H9T3,Q96N67,Q8IXJ6,P19784,Q13315,O14744,Q9UQB8,Q9BPX3,Q9HCK8,P47897,Q12830,O75592,P63167,P27695,P28482,P31939,P60953,Q15042,Q7Z460,Q9UID3,Q66K74 50 +Regulation of anatomical structure morphogenesis 0.1923083551186697 0.2086481433499566 0.8347229246489087 1.0 1.0 159 P49841,P31146,Q9Y263,Q14185,O75116,P46109,Q08209,P21359,Q00535,Q7L576,Q9P258,Q9UL63,Q9Y5V3,O14965,Q9UPN3,Q14999,P35241,O60610,Q6XZF7,P40763,P23381,P61586,Q5VZL5,Q9Y6C9,P78527,Q9GZT9,Q92908,Q9HCE1,Q7Z6Z7,P50570,O00429,Q7KZI7,O60271,Q9UQB8,Q14155,Q13418,Q16512,P63167,P35580,Q13464,P35579,P60953,Q7Z460,Q9P265,P46821,Q15334 46 +Regulation of phosphatase activity 0.3698745142109002 0.2079859477584164 0.8352399395012045 1.0 1.0 21 Q13464,P42345,Q15257,O75116,P42858,P67870,P62942 7 +Response to epidermal growth factor 0.3535583640345336 0.2076038001461703 0.835538336926573 1.0 1.0 15 Q06124,P28482,P51452,P46940,Q9UQB8 5 +Pyridine containing compound biosynthetic process 0.318260291449031 0.2075728671625194 0.8355624917777267 1.0 1.0 5 O00764 1 +Cellular response to interferon beta 0.3221388578468191 0.2068683153599136 0.8361127019301147 1.0 1.0 6 P49427 1 +Response to interferon beta 0.3221388578468191 0.2068683153599136 0.8361127019301147 1.0 1.0 6 P49427 1 +Regulation of chromosome separation 0.393682709470715 0.2058498136980568 0.8369082286544116 1.0 1.0 37 Q969U7,Q15398,P68400,P50748,Q9UJX5,O43670,Q14674,Q9H900,P19784,P14635,Q5JVF3,Q13315,P53350,Q13618 14 +Germ cell development 0.3957198609278544 0.2057370106632568 0.8369963466191823 1.0 1.0 43 Q5TAX3,Q8NHU6,Q14997,Q8IXJ6,O95248,P62753,Q96RD7,Q13315 8 +Regulation of spindle assembly 0.3495431086568319 0.2049446580303506 0.8376153636151629 1.0 1.0 14 Q14204,Q8WUX9,P53350 3 +Cellular response to heat 0.3859382940032447 0.2047995014354931 0.8377287765542634 1.0 1.0 30 Q99543,P49841,P17612,P42345,Q53FT3,P21359,Q13535,Q13315,Q9UER7 9 +Glutamine metabolic process 0.3462284780023904 0.2045166389288158 0.8379497907909346 1.0 1.0 13 P17812,P27708,Q06210,O15067 4 +Positive regulation of cytokine production involved in immune response 0.3460313221344254 0.2039724045399626 0.8383750635457556 1.0 1.0 13 P14174,Q9UDY8 2 +Histone ubiquitination 0.3675271369631703 0.2014573851993661 0.8403409479527277 1.0 1.0 21 Q6W2J9,O95071,Q9UPT9,Q7Z6Z7 4 +Response to muscle stretch 0.3160085598718972 0.201292228861009 0.8404700786786274 1.0 1.0 5 P06744,Q16539,P19022 3 +Regulation of response to oxidative stress 0.3673039899532004 0.2008434791122701 0.8408209641501418 1.0 1.0 21 P00374 1 +Receptor signaling pathway via stat 0.3538554779084955 0.2002693558101036 0.8412699275552267 1.0 1.0 16 P22059,O75925,Q00535,Q9UIV1 4 +Positive regulation of establishment of protein localization to mitochondrion 0.350588794111511 0.1994240637759565 0.8419310383450729 1.0 1.0 15 P19784,Q96EP0,Q7Z6Z7 3 +Leukocyte apoptotic process 0.3713410339665708 0.1993811935505344 0.8419645705219618 1.0 1.0 23 P42574,P14174,P42771,P49327,P62753,Q9HCL2 6 +Positive regulation of dna metabolic process 0.2707618685578806 0.1990060284012643 0.8422580289307364 1.0 1.0 90 P09429,P28482,Q99504,P18074,Q93008,Q7Z4V5,Q96L91,Q01804,Q13535,Q13315,Q9Y4A5,P78527,Q96HR8 13 +Regulation of dna templated transcription initiation 0.3471020129164882 0.1982608175612519 0.8428410061973772 1.0 1.0 14 Q86VP6,P09429,Q15648,O60244,Q9Y2X0 5 +Dendritic spine development 0.3787184229287621 0.1979882960502535 0.843054220872975 1.0 1.0 27 Q9BRT6,Q06787,P61160,Q05086,P60953,Q9H2U1,P18085,Q00535,O60678,Q6DN90,Q9UQB8,Q15334,O00401,P43034 14 +Copii coated vesicle cargo loading 0.3301534075100577 0.1978634184671699 0.8431519261183655 1.0 1.0 9 P55735,P53992,O95486,Q15436 4 +Regulation of antigen receptor mediated signaling pathway 0.3368451270369129 0.1969730114030264 0.8438486577989979 1.0 1.0 11 Q9UDY8 1 +Positive regulation of leukocyte cell cell adhesion 0.3763108476617973 0.1963559742214566 0.8443315529032918 1.0 1.0 26 Q06124,P09429,O14617,O43290,Q9UDY8,Q9HCL2 6 +Dna modification 0.3839141674200172 0.1952149726798277 0.8452246580508442 1.0 1.0 31 Q9NRZ9,P27695,P29372,P09874,Q93008,Q01804,Q8N3C0,Q8NB78,P26358 9 +Regulation of rna binding 0.3254406894729975 0.1950127200517507 0.8453829896383851 1.0 1.0 8 Q06787,Q04637 2 +Regulation of ossification 0.3424280382708786 0.1941834316217272 0.8460322555994484 1.0 1.0 13 Q06124,Q6W2J9,P28482 3 +Cellular response to ionizing radiation 0.3731888192165313 0.1930900983923831 0.8468884070756211 1.0 1.0 25 O60921,P49917,O96017,P50570,Q13535,Q13315 6 +Learning 0.3617259006949401 0.1923487128873937 0.8474690633551631 1.0 1.0 20 P78559,P42858,P21359,Q9NPQ8,P04035,Q15334 6 +Cellular pigmentation 0.3278759004917955 0.1917421813167298 0.8479441630598452 1.0 1.0 9 O00203,O14617 2 +Mitotic dna replication 0.3343787343604801 0.1903806097647992 0.8490108909643874 1.0 1.0 11 Q9BY42,P18858,P09884,P33991,P33993 5 +Pyrimidine nucleoside monophosphate biosynthetic process 0.3236703315264197 0.1902811494829781 0.8490888243251153 1.0 1.0 8 P33316,P27708,P04818 3 +Pyrimidine nucleoside monophosphate metabolic process 0.3236703315264197 0.1902811494829781 0.8490888243251153 1.0 1.0 8 P33316,P27708,P04818 3 +Regulation of stem cell differentiation 0.3654042584453678 0.189391673743552 0.849785849769962 1.0 1.0 22 Q92908,P40763,Q9NYV4,Q00534,Q9Y6C9,P78527 6 +Cellular response to acid chemical 0.3496964141884823 0.189121460087363 0.8499976222700434 1.0 1.0 16 P17655,P42345,P26358,Q9P2J5,Q9UQB8,Q9P0V3 6 +Dna replication independent chromatin organization 0.3155684748892067 0.1889558550683308 0.850127415985878 1.0 1.0 6 Q8TEX9,O14929 2 +Pyrimidine nucleoside triphosphate metabolic process 0.3337341956594486 0.1886810606855017 0.8503427963409538 1.0 1.0 11 P22392,P15531,P17812,P27708,P04818 5 +Histone h4 acetylation 0.3749337497324027 0.1877101584151228 0.8511038665637038 1.0 1.0 27 Q9UPT9,Q9Y4A5,P49407 3 +Positive regulation of developmental process 0.1833225555980345 0.186989766289267 0.851668656747067 1.0 1.0 210 Q15648,P17655,P49841,Q9BRT6,Q9Y263,Q14185,Q8IY37,P09874,Q9P2D1,Q96FZ2,Q9HCL2,Q9Y5V3,O14965,Q9UPN3,Q14999,P20248,P40763,Q86TU7,O43290,Q99873,P78527,Q9Y6C9,Q92908,Q9H4M9,Q9H8V3,P49917,Q96QE3,P42345,O00203,P50570,Q15418,O00429,Q8IXJ6,Q5JVF3,O60271,Q9UDY8,O14744,Q9UQB8,Q14155,O96017,P22392,P09429,O14617,P27695,Q06787,Q04637,P60953,Q92974,Q7Z460,P46821,Q15334 51 +Regulation of fibroblast migration 0.3182812710386593 0.185966073032966 0.8524713669888953 1.0 1.0 7 Q9P258,Q14155 2 +Monosaccharide catabolic process 0.3450173015374198 0.1846277363918829 0.8535210294366027 1.0 1.0 15 P08237,P85037,P17858,Q96C23 4 +Response to progesterone 0.3093993136690328 0.1835404866591324 0.8543739545276361 1.0 1.0 5 P06744,P04818 2 +Negative regulation of protein serine threonine kinase activity 0.3580107779858526 0.1825889938041055 0.8551205208361292 1.0 1.0 20 P42574,P42771,P21359,P53350,Q9Y3I1 5 +Nerve development 0.3206426743498206 0.1823584537218411 0.8553014281921951 1.0 1.0 8 Q9P2D1 1 +Anterior posterior pattern specification 0.3542778615252256 0.1795625075777183 0.8574960408098087 1.0 1.0 19 Q9HCM4,Q8NHU6,P78527,Q13315 4 +Cellular response to alkaloid 0.3193981230920727 0.1791639103333928 0.8578090005494605 1.0 1.0 8 P42574,P20248,P55212 3 +Regulation of cell junction assembly 0.3778898198573565 0.1789577595463514 0.8579708691877099 1.0 1.0 31 Q9H2G2,Q9HCM4,P63167,Q9UPN3,P17612,Q13464,Q04637,O75116,P51452,Q9P1Y5,Q7Z460,P61586,Q9P258 13 +Associative learning 0.3365624254048585 0.1788918809454093 0.8580225980179081 1.0 1.0 13 P78559,P21359,Q9NPQ8,Q00535,P04035 5 +Macrophage differentiation 0.3155168704166645 0.1788180351144237 0.8580805835570344 1.0 1.0 7 P60953,P09874 2 +Response to virus 0.266970382025498 0.1787105379538835 0.8581649943055403 1.0 1.0 90 O75569,Q9UIV1,O95352,Q9BUI4,Q9HCL2,Q9UII4,P25787,Q13309,Q00534,Q92499,Q9HCE1,Q9NUQ8,O14802,P26641,O15111,Q14258,Q9NW08,P63241,Q92538,Q7Z7L1 20 +Dna dependent dna replication 0.3320849516414517 0.1782589298656617 0.8585196313942531 1.0 1.0 75 P23921,Q92547,Q9BY42,P46063,Q13535,P28340,Q9UBD5,Q9Y3Z3,P78362,P49427,P18858,P17096,Q96QE3,Q07864,P49005,O43913,Q8WTT2,Q9BTE3,P35251,Q7Z7L1 20 +Autophagosome maturation 0.3424779312552846 0.1781237041810771 0.8586258264651352 1.0 1.0 15 Q9H269,Q8WUX9,Q99816 3 +Dna templated transcription termination 0.3183980606587874 0.1766232487119899 0.8598043313513328 1.0 1.0 8 O14744,Q9UNY4 2 +Positive regulation of cell cycle g2 m phase transition 0.3350772117614539 0.1751472124397345 0.8609639614256328 1.0 1.0 13 P30307,Q96QE3,P23921,P14635,Q9P258 5 +Protein localization to nucleus 0.1880197357919452 0.1748657305936431 0.8611851383551372 1.0 1.0 123 Q15648,P49841,P09874,Q08209,O15397,Q92973,P21359,O95071,Q00535,Q4G0J3,Q9UI26,Q9Y5K6,Q96D46,Q9Y5V3,O14980,Q7Z4Q2,P61970,P55060,Q9Y5L0,P40763,Q9UH99,Q6GQQ9,Q8NFQ8,Q9H8V3,Q96P70,Q53FT3,Q5SRE5,O00629,Q13501,Q7L2J0,P51858,P53350,Q8TEX9,O95373,O00410 35 +Positive regulation of organelle assembly 0.3748596401960509 0.1747649853854219 0.8612643024684081 1.0 1.0 30 P27695,Q15042,P42858,Q14204,Q9BPX3 5 +Regulation of macrophage differentiation 0.2973134328358256 0.1742601074610887 0.8616610491473393 1.0 1.0 3 Q14790,Q13546 2 +Positive regulation of macrophage differentiation 0.2973134328358256 0.1742601074610887 0.8616610491473393 1.0 1.0 3 Q14790,Q13546 2 +Negative regulation of striated muscle cell apoptotic process 0.2973134328358235 0.1742601074610836 0.8616610491473433 1.0 1.0 3 O95817,Q96QC0 2 +Respiratory chain complex iv assembly 0.3136393649316708 0.1740656877609743 0.8618138387017646 1.0 1.0 7 O75880 1 +Negative regulation of epithelial cell migration 0.3209709488592885 0.173921883022988 0.8619268545570389 1.0 1.0 9 P67870 1 +Exploration behavior 0.3056253986161349 0.173865517712091 0.8619711527130864 1.0 1.0 5 Q9HB07,Q15334 2 +Appendage morphogenesis 0.3344260067222699 0.1735216041443795 0.8622414478022908 1.0 1.0 13 Q9P2D1,Q9C0E8 2 +Rna phosphodiester bond hydrolysis endonucleolytic 0.3764883791500617 0.1719169041172898 0.8635028568815595 1.0 1.0 32 Q2NL82,P27695,Q14692,O75818,P78316,Q99575,O15091,O75691,Q5SY16,O95707,Q96F86,Q96DE0,Q9BQ52 13 +Vitamin metabolic process 0.3751336803179982 0.1718236730381226 0.8635761539110365 1.0 1.0 31 P00374,Q99707,P29375 3 +Post golgi vesicle mediated transport 0.3835092724970909 0.1717413918587928 0.8636408432509177 1.0 1.0 41 Q7Z3U7,O43795,Q96KP1,O60826,O14617,Q9UPN3,P50570,O15027,Q8TAG9,Q92538,O95782,Q4J6C6,P57737,O14976,Q9P2R3,Q15334,P63244,Q9Y6D5 18 +Negative regulation of amyloid precursor protein catabolic process 0.3199529346999468 0.1713890175961695 0.8639178897030728 1.0 1.0 9 P27695,Q13464 2 +Ribosomal subunit export from nucleus 0.3328602205790884 0.1696535800857662 0.8652825824613977 1.0 1.0 13 P62841,Q9NVU7,Q96D46 3 +Mitotic nuclear membrane organization 0.3114643376930507 0.1686641663645216 0.866060806003808 1.0 1.0 7 Q8IXJ6,Q9H6H4 2 +Positive regulation of phospholipid metabolic process 0.2992616965991764 0.1684192781413998 0.8662534429603166 1.0 1.0 4 P17655 1 +Response to abiotic stimulus 0.179787278702462 0.1678600755450934 0.8666933594853288 1.0 1.0 230 P17655,P49841,Q9UHD1,Q9UNS2,P09874,Q99504,O75116,Q92547,Q13432,O95352,Q13526,P62136,P21359,P54132,P31751,Q00535,P30419,Q13535,P28340,P49327,Q13144,Q9UPY5,Q7L576,Q9UER7,Q9UKL3,P52701,P17612,P42858,Q68E01,P20248,O75348,P49770,P10155,Q9NPQ8,P61586,Q99543,P78527,P18074,Q9GZT9,Q92908,Q92544,Q9H8V3,P49917,P42345,P42574,P50570,Q53FT3,Q9Y620,Q8IXJ6,Q96RU2,Q13315,P31689,O94966,P06744,O96017,O60921,O75592,Q16512,Q06787,Q6PJG6,Q00796,P22681,P04035,Q92974,P61254,Q99996,P46821,Q14790,Q13620,Q6P6C2 70 +Negative regulation of nuclease activity 0.2944928658261684 0.167195223107733 0.8672164429241194 1.0 1.0 3 Q15554 1 +Fibroblast migration 0.3273516098102575 0.1641892703263296 0.8695821475200778 1.0 1.0 12 P46940,Q9P258,Q14155,Q13418 4 +Innate immune response activating signal transduction 0.2975150194554284 0.1641337981630386 0.8696258155160059 1.0 1.0 4 Q16512 1 +Response to lectin 0.2975150194554284 0.1641337981630386 0.8696258155160059 1.0 1.0 4 Q16512 1 +Cell surface receptor signaling pathway involved in cell cell signaling 0.324726609792426 0.1636911213417794 0.8699743074109223 1.0 1.0 76 Q70CQ2,P49841,P68400,Q08209,Q13526,P62136,P51532,Q13614,O95071,Q00535,Q9GZS3,Q9UPN3,Q96BN8,P61586,P67870,Q7KZI7,P19784,Q9UQB8,Q13418,Q9HCK8,P60953,P40818,Q15042,Q9UGU5,Q15334,Q13618 26 +Ensheathment of neurons 0.3672086636382677 0.1635179015834219 0.8701106794177691 1.0 1.0 28 P42345,Q13614,P31751,P21359,P49770,Q13144,Q8TEW0,Q8IXJ6,Q7L576,Q96P11,P18074,Q13418 12 +Positive regulation of peptidyl tyrosine phosphorylation 0.3392382225387505 0.1628750956260673 0.8706167797747919 1.0 1.0 16 Q06124,P42345,P14174,Q9H223,P22059,Q15334 6 +Negative regulation of mitotic cell cycle phase transition 0.376891880270531 0.1620334481577104 0.8712795140818066 1.0 1.0 52 O60921,O96017,P50748,Q92547,O43670,Q68E01,P61254,P14635,Q5JVF3,Q7Z7L1,Q13315,P53350,Q13564,P78527,Q9Y3I1 15 +Negative regulation of phosphorus metabolic process 0.2635561391563313 0.1616153656506075 0.8716087563539932 1.0 1.0 90 P49841,P09874,O75116,P46109,P42771,P21359,Q12923,P51452,P40763,P78527,Q9Y3I1,P42574,Q15257,Q8TEW0,Q8IXJ6,O60271,P31689,P62942,P47897,Q16512,P63167,Q13464,Q04637,P22681,Q96GX5,P46940,P53350,P04035,O95373,O00410,Q99816 31 +Regulation of actin filament based process 0.2685677852190109 0.1613355077308838 0.8718291584375315 1.0 1.0 89 P31146,O75116,Q00535,Q9Y2A7,Q7L576,Q9Y5K6,P35241,Q13045,Q96F07,Q8WUW1,Q9H8V3,P42345,P47755,Q9Y613,Q9UQB8,Q9BPX3,Q16512,O75592,P63167,Q13464,P35579,P60953,Q99996,P46940,Q7Z460,Q9UHB6,O00401 27 +Smooth muscle cell proliferation 0.3467648201962335 0.1610553123617221 0.8720498362489524 1.0 1.0 19 Q5VZE5,P26358 2 +Leukocyte differentiation 0.3483329320034065 0.1599842809577731 0.8728934566995197 1.0 1.0 68 Q15648,P09874,P21359,P49327,Q9P2D1,Q6IBW4,P40763,Q00534,O43290,P78527,Q9Y3I1,P49917,P42345,O00203,Q5JVF3,P62753,Q13315,Q9ULT8,Q9UDY8,P09429,O14617,P35579,P60953 23 +Amp metabolic process 0.3377333937128485 0.1593100073739034 0.8734246367080516 1.0 1.0 16 P00492,P31939,P11908,Q01433,O15067 5 +Regulation of multicellular organismal development 0.181962108078542 0.159212710177945 0.8735012903200161 1.0 1.0 193 Q15648,O75116,Q13614,P21359,Q00535,Q9P2D1,Q9UPN3,Q14999,Q99956,P20248,P40763,Q9UBS4,Q00534,O43290,Q96P11,P78527,Q99873,Q9Y3I1,Q06124,P49917,P42345,O00203,Q8TEW0,Q8IXJ6,Q96N67,Q5JVF3,Q9UDY8,Q9UQB8,P22392,P09429,O14617,P27695,Q9C0E8,Q7Z460,P46821,Q6W2J9 36 +Citrate metabolic process 0.2951247667869898 0.1583878628775006 0.8741511770804877 1.0 1.0 4 P53396 1 +Positive regulation of protein polymerization 0.3680139077339287 0.1577345645497941 0.8746659628530198 1.0 1.0 30 Q16512,Q14008,P42345,Q9Y295,Q99996,Q7Z460,Q9Y2A7,P46821,Q9UQB8 9 +Epiboly 0.3106344198795215 0.1577008782711083 0.8746925083944168 1.0 1.0 8 Q7Z460,P20248,P42345 3 +Morphogenesis of an epithelial sheet 0.3106344198795215 0.1577008782711083 0.8746925083944168 1.0 1.0 8 Q7Z460,P20248,P42345 3 +Nucleobase metabolic process 0.3571131404582298 0.1575716500652454 0.8747943444202588 1.0 1.0 24 P00492,P07741,P28482,P42345,P17812,P27708,P11172,Q9P2T1,Q9BPU6,P04818 10 +Regulation of catabolic process 0.1735771631796961 0.1574326503703233 0.874903883011789 1.0 1.0 319 Q96EP0,Q9UIV1,P49841,P68400,P67809,O75116,O95352,Q86W50,A5YKK6,Q13464,P31751,Q13614,Q92990,Q00535,Q13190,Q9HAD4,Q96HR8,O00178,O14965,O14980,Q5TAX3,Q9Y5K8,P17612,P62081,P35241,P42858,Q9Y2L1,P40763,P46777,Q9BW61,Q9Y3I1,Q9HCE1,Q86TB9,Q7Z6Z7,P42345,P42574,O00443,O00429,Q8IXJ6,P19784,Q5JVF3,O43432,Q13315,Q9ULT8,O43242,P11802,Q9P0V3,Q05639,O75832,O96017,P78559,O60826,O75925,P27695,O75592,Q14147,Q96C86,P09429,P04035,P40818,Q06787,Q6PKG0,Q15042,P61289,Q04637,P85037,Q99570,P53350,Q9Y2V2,Q6P6C2 70 +Regulation of ubiquitin protein transferase activity 0.3547539109234121 0.1571111602838597 0.8751572421814697 1.0 1.0 23 P15880,P62081,P62841,P60866,Q96GX5,P61927,O00429,P46777,P53350 9 +Negative regulation of telomere maintenance 0.3337997042059529 0.1570376002236249 0.8752152150249626 1.0 1.0 15 Q8IZH2,Q13315 2 +Negative regulation of viral process 0.3475843526404201 0.1569430369565281 0.8752897415252359 1.0 1.0 20 P78362,Q96SB4,Q4G0J3 3 +Positive regulation of keratinocyte differentiation 0.3027299322249331 0.1568804232403642 0.8753390887912205 1.0 1.0 6 P22392 1 +Apical junction assembly 0.3566352021548264 0.1564467974787525 0.8756808522162358 1.0 1.0 24 Q13464,P17612,O75116,P55196,Q8TEW0,Q16513,Q9BTW9 7 +Detoxification of nitrogen compound 0.2898507462686602 0.1559850150256811 0.8760448329122814 1.0 1.0 3 P28161,P21266 2 +Roof of mouth development 0.3098776825605973 0.1559326264503465 0.8760861276720562 1.0 1.0 8 Q9P2D1 1 +Regulation of lymphocyte apoptotic process 0.3098730505249077 0.1559218445982082 0.8760946263988145 1.0 1.0 8 Q9HCL2 1 +Regulation of protein dephosphorylation 0.36483467159715 0.1538619802757157 0.8777185624121357 1.0 1.0 29 P63167,P49841,Q69YH5,Q13464,P42345,O75116,Q15257,Q96GX5,P42858,P67870,Q14738,P62942 12 +Mitotic dna integrity checkpoint signaling 0.3610991468842502 0.153115354900714 0.878307307200026 1.0 1.0 27 O60921,O96017,Q92547,P61254,Q13315,P53350,P78527 7 +Regulation of cell projection assembly 0.3756209163981061 0.1530501330249485 0.8783587405304671 1.0 1.0 49 Q9NT62,P49841,Q8TC07,P27695,P61160,P42345,Q06787,P50570,P35241,P60953,P42858,Q9P258,P07737,Q9Y2A7,Q7L576,Q8NCA5,O00401,Q8WUW1 18 +Positive regulation of dna templated transcription elongation 0.3377440451422016 0.1526936889003139 0.8786398379297755 1.0 1.0 17 O75909 1 +Morphogenesis of embryonic epithelium 0.3588848108187448 0.1522991349002355 0.8789510072109163 1.0 1.0 26 Q9HCM4,P17612,P25440,P62081,P42574,Q92990,Q96Q89,Q9ULT8 8 +Er associated misfolded protein catabolic process 0.3045427375971221 0.1522199807271642 0.8790134352593895 1.0 1.0 7 Q9BUN8,Q92890,Q9NYU2,Q9HCN8,P46379,P55072 6 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.3186962802717263 0.151785436390539 0.8793561691126754 1.0 1.0 11 Q99504 1 +Metaphase anaphase transition of cell cycle 0.369677713490056 0.1493808294490696 0.8812531378831596 1.0 1.0 34 Q969U7,Q15398,P50748,Q9UJX5,O43670,Q14674,Q9H900,Q9H1A4,P14635,Q15645,Q5JVF3,Q13315,P53350,Q13618,O43683,Q99741,O43684 17 +Nucleobase biosynthetic process 0.3303977357973879 0.1492548079944574 0.881352573752624 1.0 1.0 15 P00492,P07741,P42345,P17812,P27708,P11172 6 +Microtubule based movement 0.3018212129173345 0.1488939950538162 0.8816372796497445 1.0 1.0 81 Q15398,Q86Y56,Q99661,Q14203,Q9UBF2,Q15058,Q15554,P42858,Q9Y496,Q14204,Q9Y678,Q9NZ32,O00203,Q9P1Y5,Q96Q89,O43237,O60333,P78559,P57076,O14617,P27695,Q9BW19,Q00796,P60953,P46821,Q66K74 26 +Leukocyte adhesion to vascular endothelial cell 0.2950496746159083 0.148559196902537 0.8819014717944709 1.0 1.0 5 Q13464 1 +Anaphase promoting complex dependent catabolic process 0.310286232252241 0.1485545995883804 0.8819050996667424 1.0 1.0 9 Q9UJX5,P53350 2 +Secretion 0.1862145110667465 0.1481708109316475 0.8822079670174419 1.0 1.0 154 Q9UM54,Q15648,P49841,P07741,P31146,Q08209,Q92905,P21359,Q00535,Q16850,Q4J6C6,Q9P2D1,Q9Y6D5,Q9Y5K6,Q9UBF2,P20645,P14174,P15531,P22059,P53985,Q9Y678,Q06124,Q96QK1,Q96KP1,P53621,O00443,Q92614,O00429,O95486,P17858,P43034,Q16512,O75592,P27695,Q06787,P35580,Q7Z392,P08237,Q13555,P22681,P35579,Q15042,Q8TAG9,Q7Z460,Q9Y5X3,P04035,Q15334,Q99816 48 +Regulation of proteolysis 0.1848409622690976 0.1467623252454715 0.8833196227089724 1.0 1.0 165 P49841,P68400,O75116,Q92990,P49327,Q00535,Q9UKL3,O14965,O14980,P17612,P62081,Q01804,Q14997,P20248,P40763,P46777,Q96F07,Q9BW61,Q8IXJ6,P19784,Q5JVF3,Q9ULT8,Q15020,Q9UDY8,Q9NR09,O75832,P78559,O60826,O75925,Q06787,Q13464,P09429,P35579,P61289,P53350 35 +Mannosylation 0.3057597695265867 0.1465479618938866 0.8834888304606343 1.0 1.0 8 O43505 1 +Multicellular organismal movement 0.3125781405272712 0.145776440088493 0.884097875282194 1.0 1.0 10 P78559 1 +Regulation of muscle cell differentiation 0.3559129159319624 0.1455231821533265 0.8842978138557134 1.0 1.0 26 P67809 1 +Neural tube formation 0.3448958777130068 0.1451998169283278 0.8845531104725131 1.0 1.0 21 P17612,P25440,P62081,P42574,Q92990,Q96Q89,Q9ULT8 7 +Sensory organ morphogenesis 0.3553695049739507 0.144307416046627 0.8852577224471414 1.0 1.0 26 Q9UM54,O75569,P28482,Q8NHU6,P21359,Q9P2D1 6 +Cell cycle dna replication 0.3355807291593091 0.1417043860299027 0.8873135103547087 1.0 1.0 18 Q96QE3,Q15554,Q9BY42,P18858,P54132,P09884,P33991,P33993 8 +Regulation of telomere maintenance via telomere lengthening 0.361014551003852 0.1415314482050338 0.8874501180069616 1.0 1.0 30 P28482,Q8IZH2,Q13535,Q13315,Q96HR8 5 +Regulation of sister chromatid cohesion 0.3101657241336857 0.1404991465462457 0.8882656267598388 1.0 1.0 10 Q14674 1 +Positive regulation of mitotic cell cycle 0.3713589779294703 0.1403800851153682 0.8883596918122367 1.0 1.0 47 Q9UPT9,Q15398,P23921,Q9P258,P51452,P35241,P08243,Q99741,Q06124,P30307,Q9UJX5,Q16513,P14635,P11802,Q7L2J0,P43034,P27695,Q04637,Q14674,Q13618 20 +Transmission of nerve impulse 0.2988618869668867 0.1395729031570588 0.8889974511694354 1.0 1.0 7 Q06787,P43034,P42345 3 +Receptor internalization 0.3446042486180861 0.1393639856996068 0.8891625298406667 1.0 1.0 22 P50570,P49407,Q00610,Q13614,Q15334,Q9UL63 6 +Cytoskeleton dependent intracellular transport 0.3549314486105355 0.1392295036822442 0.889268794986352 1.0 1.0 62 Q9UBF2,P78559,O14617,O94832,P27695,O60333,O00203,Q9P1Y5,P42858,Q9Y496,Q14204,Q9UH99,P46821,Q9Y678,Q66K74,Q9NZ32 16 +Myoblast fusion 0.2986792338688507 0.1391789766746674 0.8893087209860759 1.0 1.0 7 P35579,P17655 2 +Tissue remodeling 0.3285902738139939 0.1387953714336377 0.8896118516448777 1.0 1.0 16 O75116,Q9UBB6,Q9P2D1,P21359 4 +Response to misfolded protein 0.3047248803827714 0.1364173036669656 0.8914913952033512 1.0 1.0 9 Q9BUN8,Q92890,Q9NYU2,P46379,Q9HCN8,Q9UNE7,Q13618,P55072 8 +Cell cell adhesion 0.1785364935969694 0.1361570386457301 0.8916971370008446 1.0 1.0 108 P31146,O00299,Q92990,Q9UPY5,Q9HCL2,Q9Y5K6,Q9HCM4,P51452,P35241,P20248,Q9NPQ8,P31949,Q96F07,O43290,Q06124,P42574,O00203,P55196,Q9P1Y5,Q9UDY8,Q9UQB8,Q13418,P09429,O14617,Q13464,P35579,Q15334 27 +Positive regulation of myoblast fusion 0.2893915958937568 0.1361183738483979 0.8917277024869144 1.0 1.0 5 Q9H4M9,P17655 2 +Regulation of myoblast fusion 0.2893915958937568 0.1361183738483979 0.8917277024869144 1.0 1.0 5 Q9H4M9,P17655 2 +Positive regulation of type i interferon production 0.3404213783310992 0.1355191994388119 0.8922013853274415 1.0 1.0 21 Q9BUI4,O14802,O15111,Q9NW08 4 +Regulation of anatomical structure size 0.2368874080001715 0.13510000715559 0.8925328045211263 1.0 1.0 94 P49841,P31146,O75116,P62136,Q00535,Q9Y2A7,Q9P2J5,Q7L576,Q9Y666,Q9UPN3,P35241,Q13045,Q96F07,Q9BXP2,Q8WUW1,P42345,P50570,O00443,P47755,Q9UQB8,Q9BPX3,Q13464,Q9P265,Q9UHB6,P46821 25 +T cell activation 0.3532816706116157 0.1347249100035023 0.8928293774103986 1.0 1.0 62 Q06124,P49917,P09429,O14617,Q9UDY8,P42345,O00203,P51452,P17812,P42574,O43290,P62753,Q00534,Q9P2D1,Q9HCL2,P62942,P78527 17 +Negative regulation of actin filament depolymerization 0.3266070006239601 0.1346048362591951 0.8929243176296666 1.0 1.0 16 P35241,Q9UHB6,P47755,Q9BPX3 4 +Cellular transition metal ion homeostasis 0.3348465267536344 0.1344372917011534 0.8930567947590271 1.0 1.0 19 O60826,O14617 2 +Positive regulation of cytokinesis 0.3204134077009107 0.1342562296964629 0.8931999634596994 1.0 1.0 14 Q9H8V3,Q15058,P60953,Q96Q89,Q16513,P61586,Q13618 7 +Sprouting angiogenesis 0.3137372610716593 0.1336928776455298 0.8936454374174876 1.0 1.0 12 Q96BN8,P60953,O00443 3 +Virion assembly 0.3136931593356097 0.1336011619251524 0.8937179653440255 1.0 1.0 12 Q8WUX9,Q99816 2 +Positive regulation of substrate adhesion dependent cell spreading 0.3200054669989848 0.1334075815793005 0.8938710497722278 1.0 1.0 14 Q14185,P60953,P50570,Q14155,Q13418 5 +Meiotic cell cycle process 0.3685906818872366 0.1331706894491929 0.8940583907821342 1.0 1.0 45 O60921,O14965,P30307,P52701,Q15021,Q15003,O95067,P35579,Q14674,Q9Y620,Q8IXJ6,Q9NTJ3,Q13315,P53350,P42695 15 +Alditol metabolic process 0.2957227516875321 0.1329127175928612 0.8942624089590043 1.0 1.0 7 Q16822,Q00796 2 +Signal transduction in absence of ligand 0.3227592962436328 0.1327711407398853 0.8943743786095917 1.0 1.0 15 Q99504,P49841,P49327,P21359 4 +Response to mitochondrial depolarisation 0.295601411835465 0.1326599591182677 0.8944623108949041 1.0 1.0 7 Q7Z6Z7 1 +Enzyme linked receptor protein signaling pathway 0.1813862677254208 0.1317050008050782 0.8952176299083974 1.0 1.0 119 P49841,P09874,P43490,Q93008,P46109,Q13526,P31751,Q8TBX8,Q92600,P51452,P20248,P40763,Q96F07,P67870,O14654,Q92908,Q06124,P42574,P50570,O00443,Q8IXJ6,P11802,Q9UQB8,P62942,Q14155,Q13418,Q16512,P27695,P28482,P22681,P46940,Q9Y5X3,Q99816 33 +Negative regulation of cell cycle process 0.2930442845788221 0.1315368562678571 0.8953506327591081 1.0 1.0 82 O43670,Q92547,Q5TBB1,P54132,Q13535,Q15554,P50748,Q68E01,Q08J23,Q13564,P78527,Q99741,Q9Y3I1,Q06124,Q969U7,Q96RU2,P14635,Q5JVF3,Q13315,O96017,O60921,Q14674,Q99459,P61254,Q9H900,Q7Z7L1,Q7Z5K2,P53350 28 +Response to x ray 0.3190526398469773 0.1314405494087443 0.8954268131087153 1.0 1.0 14 P42574,P49917,Q13315 3 +Nuclear transcribed mrna catabolic process 0.3538270518319361 0.1313866381632186 0.8954694582340978 1.0 1.0 61 Q9UIV1,Q5TAX3,Q86TB9,P67809,Q14147,Q96C86,Q8IZH2,A5YKK6,Q9Y2L1,Q6PGP7,Q5JVF3,Q13315,Q96F86,Q15477 14 +Regulation of leukocyte proliferation 0.3527079702285191 0.130644731363811 0.8960563554465841 1.0 1.0 28 Q16512,P09429,Q96QE3,P28482,P14174,P42574,Q92990,Q13315,Q9HCL2 9 +Negative regulation of cell activation 0.3379724218711804 0.1304216583306792 0.8962328320675557 1.0 1.0 21 P09429,P42574,P51452,Q13315,Q9Y3I1 5 +Mitotic recombination 0.3087608118025732 0.1303247661325052 0.8963094866249839 1.0 1.0 11 Q9Y620,P18074,P20585 3 +Telencephalon development 0.3666073693153495 0.1290799629036601 0.8972943766443615 1.0 1.0 43 Q9H0D6,P00492,P49841,Q15058,Q9P2D1,P31939,P42574,P46109,P21359,Q13144,O43776,Q00535,P61586,P19784,Q00534,Q9UPY5,Q96P11 17 +Myotube cell development 0.2818751866228625 0.1290283944649645 0.8973351810880288 1.0 1.0 4 Q8NEZ5,Q08209,Q96TA1 3 +Extracellular vesicle biogenesis 0.2974420298499462 0.1288152324676188 0.8975038521865439 1.0 1.0 8 Q99816 1 +Response to cocaine 0.3008498037813537 0.1283909756029891 0.8978395724773409 1.0 1.0 9 P50570,Q00535 2 +Somatic diversification of immune receptors 0.3497219209812989 0.128172084347015 0.898012791293465 1.0 1.0 27 P49917,P52701,P09429,Q96QE3,P20585,P18858,Q13315,Q96FZ2,P78527 9 +Epithelial cell differentiation 0.1796594409778451 0.127608073833411 0.8984591413796077 1.0 1.0 115 Q9UM54,Q15648,P49841,O75116,P31751,P49327,Q9UPY5,Q9HCM4,Q00534,P18074,Q92908,P55212,P42574,P55196,Q8NHU6,Q9P1Y5,P22392,Q13464,P60953,P46940,P46821,P04818,Q99816 23 +Filopodium assembly 0.3139342095362307 0.1274541510179042 0.8985809593436984 1.0 1.0 13 P47756,Q16658,Q06787,P60953,Q9H6U6,O00401,P15311,Q9NUL3 8 +Positive regulation of cellular biosynthetic process 0.1790464505884507 0.127206091725386 0.8987772840523507 1.0 1.0 412 Q9UM54,Q15648,Q9UPT9,P67809,P10589,P51532,Q6P1K2,O75909,Q13535,Q9H3P2,Q9H1B7,P20248,P40763,P46777,Q9NYV4,Q96P11,Q99873,Q92908,Q96QE3,P49407,Q7Z478,Q92616,Q9Y613,Q7L2J0,Q9HCK8,O14617,P27695,Q06787,Q04637,P60953,Q92974,P35251,P85037,O75569,P36507,P17655,P61457,Q92905,Q92600,Q96D46,O15371,P13639,P18615,P29375,Q96IU4,P78527,Q15418,Q8IXJ6,Q15185,O60244,Q13315,Q13418,O96017,Q12830,P51858,Q15042,Q99459,Q9Y2X0,Q9Y5B9,Q9Y5X3,Q14684,O00401,O75155,Q9UPP1,P43490,Q08209,Q13526,P62701,Q9P2D1,Q96HR8,P17096,Q13501,O15111,P09429,P28482,Q6PKG0,P08237,Q99816,Q9UIV1,P09874,O00170,P31751,Q13144,Q3B7T1,Q4G0J3,Q9UER7,Q9Y5V3,Q86VP6,Q86TU7,Q8NB78,P42345,O00203,P50570,Q5JVF3,Q14258,Q16512,P22392,P61254,P63241,Q9Y2X9 100 +Regulation of map kinase activity 0.3355849643011929 0.1255882623722095 0.9000578546553326 1.0 1.0 21 P14174,P21359,Q9NYV4,P04035,Q9Y5V3,Q99816 6 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.3461806793061672 0.1248310401825994 0.9006573130782787 1.0 1.0 26 Q9UBF2,Q96JB2,Q92538,P42858 4 +Regulation of cell cycle g1 s phase transition 0.3629456343789861 0.1247326057279314 0.900735243335391 1.0 1.0 39 O96017,P27695,P42771,Q7Z7L1,Q13315,Q7L2J0,P78527,Q9Y3I1 8 +Pyrimidine nucleotide metabolic process 0.3155686796376528 0.124428472788689 0.9009760304964468 1.0 1.0 14 P22392,P15531,P17812,P27708,P33316,P04818 6 +Negative regulation of molecular function 0.1757981313647722 0.1243932563095837 0.9010039125640834 1.0 1.0 224 P49841,P68400,O00170,O75116,Q08209,Q13526,P62136,P42771,P21359,Q9P258,Q9Y314,Q86VP6,Q9HCM4,O14965,O14981,P62081,P51452,P35241,P62841,P61927,Q96BN8,P46777,Q9UBB9,Q14558,P29375,Q9Y3I1,Q9GZT9,P42574,Q15257,P60866,Q15418,P49407,O43924,Q5JVF3,Q14240,P31689,Q9P0V3,Q7L2J0,P33993,Q9NR09,O75832,P47897,P62942,O60826,O15111,Q06787,Q13464,Q16512,P22681,P04035,Q96GX5,Q99996,P46940,Q7Z5K2,P53350,Q14684,O95373,O00410,Q99816 59 +Positive regulation of endocytosis 0.329759594150173 0.1240958085773189 0.9012394167791078 1.0 1.0 19 Q06787,P22681,P50570,P60953,P49407,Q9P2R3,O00401,Q99816 8 +Cellular process involved in reproduction in multicellular organism 0.3556108880156969 0.1240583954244109 0.9012690392554276 1.0 1.0 58 O14965,Q15003,Q5TAX3,O95067,P42345,Q8NHU6,Q14997,Q8IXJ6,O95248,Q8NB78,Q96RD7,P62753,Q13315,P53350,Q6IBW4,Q96SB4,Q9H6S0 17 +Negative regulation of protein modification by small protein conjugation or removal 0.3624924451255081 0.1237755720073604 0.9014929737713584 1.0 1.0 39 Q9Y263,P62081,P62841,P60866,P49407,P61927,Q92990,O95071,Q00535,P46777,O60678,Q96FW1,Q13501 13 +Meiotic cell cycle 0.3522197021786919 0.1230430910106951 0.9020729755042176 1.0 1.0 60 Q9BSJ2,P42695,O14965,P52701,Q15021,Q9UH99,P30307,Q96CW5,Q9Y620,Q8IXJ6,Q9NTJ3,Q13315,O60921,Q15003,O95067,P35579,Q14674,P53350,Q9H6S0 19 +Mitotic cell cycle checkpoint signaling 0.3635944716098665 0.1229955213275146 0.9021106445022492 1.0 1.0 48 O60921,O96017,P50748,Q92547,O43670,Q68E01,P61254,P14635,Q5JVF3,Q13315,P53350,Q13564,P78527 13 +Cellular response to increased oxygen levels 0.2903087506604329 0.1219732137293053 0.9029202321947916 1.0 1.0 7 O95352 1 +Positive regulation of supramolecular fiber organization 0.3634780373050625 0.1218994534609033 0.9029786484755156 1.0 1.0 44 Q14203,Q9Y613,Q16512,Q14008,P42345,Q9UQB8,O75116,P60953,Q9Y295,Q99996,Q7Z460,Q9Y2A7,P46821,Q7L576,O00401,Q8WUW1 16 +Homologous recombination 0.2975439398848541 0.1218220689037847 0.9030399356664944 1.0 1.0 9 Q9Y620,Q15645,Q13315 3 +Defense response 0.1754940047919419 0.1214576906533135 0.9033285245103372 1.0 1.0 224 Q96EP0,Q9UIV1,Q9Y263,O95352,P40429,P49327,Q9BUI4,Q9HCL2,Q9UII4,P78362,P07814,P14174,Q01804,Q13309,Q96BN8,P78527,Q06124,Q9HCE1,P55212,P42345,O00203,Q8IXJ6,Q8IWZ3,O14802,Q13315,Q9UDY8,Q96SB4,O15111,Q14258,Q8NE71,Q16512,P09429,P30046,Q9NW08,Q7Z7L1 35 +Regulation of epithelial to mesenchymal transition 0.2936216747266953 0.1212167814586298 0.9035193324478732 1.0 1.0 8 Q7Z460 1 +Cell fate commitment 0.3332874570880912 0.1210633220145708 0.9036408802373356 1.0 1.0 21 Q92908,P42345,P42574,P60953,Q96N67,P40763,Q8IWI9,P78527 8 +Chromatin remodeling at centromere 0.2737011192354147 0.1210447660396374 0.9036555776790054 1.0 1.0 3 Q9NRZ9 1 +Muscle structure development 0.1934940626473821 0.1208330818934062 0.9038232465152682 1.0 1.0 101 Q15648,P17655,P67809,Q7Z4V5,Q92990,P21359,Q00535,P26358,Q9P2D1,Q13045,Q86TU7,Q92908,P42345,P42574,Q8IXJ6,O60271,P62942,P35579,P85037 19 +Positive regulation of t cell proliferation 0.2997730253294759 0.1193267660089894 0.9050164787851336 1.0 1.0 10 Q9HCL2 1 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.2960427623368979 0.1189234217060858 0.9053360256016064 1.0 1.0 9 Q15477 1 +Stress activated protein kinase signaling cascade 0.360302850391988 0.1180143600631029 0.9060562797116009 1.0 1.0 40 P47897,P36507,P09429,P98170,P28482,P29372,P51452,P46109,P60953,Q92905,O15344,Q99956,P49327,P61586,P31689,Q9UER7,Q99873,P43034 18 +Aminoglycan biosynthetic process 0.2948786083472727 0.1167116356114847 0.9070885694113582 1.0 1.0 9 Q8NCH0,O43505,O60701,Q00610 4 +Positive regulation of cellular response to insulin stimulus 0.283601321402347 0.116351904756942 0.907373650864768 1.0 1.0 6 Q06124 1 +Response to catecholamine 0.3228972862331939 0.1160568152009878 0.9076075139426664 1.0 1.0 18 P49841,P28482,P17612,P50570,Q8IXJ6,O14744 6 +Calcium ion regulated exocytosis 0.2944378456259046 0.1158824382950538 0.9077457141278836 1.0 1.0 9 P35579,Q15042 2 +Regulation of protein containing complex disassembly 0.3589129033421462 0.1151987892907877 0.9082875582950688 1.0 1.0 40 P78559,P29372,P35241,Q9P1Y5,Q92974,P63241,Q7Z460,P47755,Q9UHB6,P46821,Q9BPX3,Q66K74 12 +Positive regulation of histone h3 k4 methylation 0.3043440585837774 0.1151815639474861 0.9083012112504014 1.0 1.0 12 Q9H3P2,P26358,P18615 3 +Odontogenesis 0.3040806497464453 0.1146919258712929 0.9086893139165158 1.0 1.0 12 Q92908,O75592,Q6W2J9 3 +Negative regulation of oxidative phosphorylation 0.2702529945334332 0.1143986242220675 0.9089218045487536 1.0 1.0 3 P61586 1 +Positive regulation of epithelial cell proliferation 0.3294428700836843 0.1137668704721839 0.9094226015722546 1.0 1.0 21 P22392,Q15648,P09429,P15531,P21359,P40763 6 +Positive regulation of kinase activity 0.3094371510570013 0.1133540536564693 0.909749864726452 1.0 1.0 76 Q00535,O75909,Q9UNI6,Q9UER7,Q9Y5V3,Q96JP5,P14174,P20248,P42345,Q08AM6,Q7KZI7,P14635,Q92616,Q9UDY8,O75832,Q16512,Q05639,P60953,P46940,Q99570,Q15334 21 +Response to nitric oxide 0.2893526486038792 0.1131295523046033 0.9099278460322464 1.0 1.0 8 P50570,Q99707,P20248 3 +Rna phosphodiester bond hydrolysis exonucleolytic 0.3380620744988502 0.1130110509864003 0.9100217939239336 1.0 1.0 25 Q8IZH2,A5YKK6,Q9Y2L1,Q9H9L3,Q96C86 5 +Regulation of filopodium assembly 0.3031038184299424 0.1128900673548154 0.9101177110926004 1.0 1.0 12 P47756,Q06787,P60953,Q9H6U6,O00401,Q9NUL3 6 +Myeloid cell development 0.3061841321444721 0.1125887795644472 0.9103565810940506 1.0 1.0 13 Q06124,P62753,P18074 3 +Stress fiber assembly 0.3417081021292885 0.1124803101010137 0.9104425809245522 1.0 1.0 27 Q16512,P63167,Q13464,P42345,O75116,P60953,P49407,Q7Z460,Q9Y613,Q13618 10 +Regulation of peptidyl tyrosine phosphorylation 0.3377406719122707 0.112414735130374 0.9104945724380098 1.0 1.0 25 Q06124,Q9UIV1,P22681,P42345,P14174,Q9H223,P22059,Q15334,Q99816 9 +Regulation of synaptic vesicle exocytosis 0.3059383151383469 0.1121399319460823 0.9107124559763816 1.0 1.0 13 Q00535,P49841,Q06787,Q15042 4 +Transcription preinitiation complex assembly 0.3056438094618296 0.1116040032510187 0.911137397720809 1.0 1.0 13 Q86VP6,P09429,Q9Y6J9,P51532 4 +Positive regulation of gtpase activity 0.3547816919741829 0.1112705204722679 0.9114018314681308 1.0 1.0 37 Q9H8V3,P49841,Q8TC07,P46109,P55196,Q13526,P31751,P21359,Q9P2J5,Q15555,Q96N67,Q15042,Q86X10,Q9HAD4,Q6DN90,O60343,Q9P258,Q14155 18 +Regulation of adenylate cyclase activity 0.2767809096915823 0.1111348316904409 0.9115094281192176 1.0 1.0 5 P21359 1 +Regulation of dephosphorylation 0.3527467534043666 0.1110930925381653 0.9115425261928674 1.0 1.0 35 P63167,P49841,Q69YH5,Q13464,P42345,O75116,Q15257,Q96GX5,P42858,Q13614,P46940,P67870,Q14738,P62942 14 +Sister chromatid segregation 0.2093087257048094 0.1105931530353616 0.9119389772653156 1.0 1.0 98 Q15398,O43670,Q6IBW4,Q9GZZ1,Q99661,P42695,Q15058,Q15021,P50748,Q99741,Q969U7,Q9UJX5,Q29RF7,Q8WUX9,P14635,Q5JVF3,Q9NTJ3,Q13315,Q9BPX3,Q15003,Q9BW19,Q9NTI5,Q14674,Q9BTE3,Q9H900,Q7Z5K2,P53350,Q13618 28 +Inner ear morphogenesis 0.2875280628692208 0.1098021155349923 0.9125663132373916 1.0 1.0 8 Q9P2D1 1 +Regulation of lamellipodium organization 0.3236252972933932 0.1077490145591802 0.9141947878128502 1.0 1.0 20 P42345,P50570,P60953,Q9Y2A7,Q7L576,Q8WUW1,Q14155 7 +Syncytium formation 0.2862295230228745 0.1074807974043241 0.9144075585196814 1.0 1.0 8 P35579,Q14012,P17655,Q9H4M9 4 +Positive regulation of multicellular organismal process 0.1748367768000256 0.1074420227841096 0.9144383180718112 1.0 1.0 215 Q15648,P09874,O75116,Q8IY37,Q9P2D1,Q96FZ2,Q9HCL2,Q9Y6D5,Q9BUI4,Q9Y5V3,Q9UPN3,Q14999,P14174,P20248,P40763,Q14204,Q96RD7,O43290,P78527,Q92499,Q92908,Q06124,P49917,P42345,O00203,Q8TEW0,Q5JVF3,O14802,Q9UDY8,Q9UQB8,O15111,P22392,P09429,O14617,P27695,P30046,Q9NW08,P46821 38 +Transport along microtubule 0.3527406047317924 0.1072608068238243 0.9145820767364554 1.0 1.0 54 Q9UBF2,P78559,O14617,P27695,O60333,Q9P1Y5,P42858,Q9Y496,Q14204,P46821,Q9Y678,Q66K74,Q9NZ32 13 +Positive regulation of stem cell differentiation 0.2785706704724126 0.1071272556988009 0.9146880246646494 1.0 1.0 6 Q9Y6C9 1 +Cognition 0.3514405241419038 0.1067103727257041 0.9150187533528452 1.0 1.0 36 P78559,P28482,P42574,P04035,P42858,P21359,Q9NPQ8,Q9P2D1,Q96P11 9 +Circadian rhythm 0.3554492093621759 0.1058646307842427 0.9156897568714056 1.0 1.0 48 Q9NRV9,O75592,P49841,Q9Y5V3,Q7Z6Z7,P42345,P43490,O75116,Q93008,O95352,P62136,Q9BQG0,P29375,O14744,P78527,P04818,Q06210 17 +Forebrain development 0.3476106387092223 0.1056453665987034 0.91586372879281 1.0 1.0 58 O75569,P00492,P49841,P46109,P21359,Q13144,O43776,Q00535,Q9P2D1,Q9UPY5,Q9H0D6,Q15058,P61586,Q00534,Q96P11,P42574,Q96N67,P19784,P63167,P27695,P31939,Q15042 22 +Cardiac septum development 0.3020626915980975 0.1052454988690089 0.9161810082924636 1.0 1.0 13 Q9P2D1,Q9ULT8,P20248 3 +Glycerol ether metabolic process 0.2812313209802655 0.1051714742672812 0.91623974540266 1.0 1.0 7 O15228,Q8WVX9,O00116,P49327,Q6IAN0,P43034 6 +Actin filament based process 0.1759100419224166 0.1044130240986234 0.9168415874405316 1.0 1.0 180 Q9UM54,O43795,P31146,O15357,O75116,P21359,Q00535,Q9Y2A7,P57737,Q6DN90,Q7L576,Q9NVU7,Q9UL63,Q9Y5K6,Q9HCM4,P35241,O60610,Q13045,Q9UH99,Q86TU7,Q96F07,Q8WUW1,Q9H8V3,O94832,P42345,P49407,Q92614,P47755,Q9Y613,Q9UQB8,Q9BPX3,Q16512,O75592,P63167,P35580,Q13464,P35579,P60953,Q92974,Q99996,P46940,Q7Z460,Q9UHB6,Q15334,O00401,Q13618 46 +Establishment of endothelial barrier 0.3133962341656156 0.1039857417258238 0.917180663678688 1.0 1.0 17 P49327,O75116,P55196,Q13464 4 +Protein depolymerization 0.3540365919850957 0.1039188107556115 0.9172337791050972 1.0 1.0 42 P78559,Q14008,Q8WWK9,Q15058,P29372,P35241,Q9P1Y5,Q92974,O15344,Q13045,Q7Z460,P47755,O14976,P46821,Q9UHB6,Q9BPX3,Q66K74,Q99661 18 +Development of primary female sexual characteristics 0.3012851642421303 0.1039034114169075 0.9172459998444455 1.0 1.0 13 P42574,Q13315 2 +Negative regulation of chromosome organization 0.3539161176938152 0.1030720975081794 0.9179057500143432 1.0 1.0 43 Q969U7,Q15554,P50748,P09874,O43670,Q8IZH2,Q14674,Q9H900,P14635,Q5JVF3,Q7Z5K2,Q13315,P53350,P33993 14 +Cellular senescence 0.3322170530876602 0.1025423331483941 0.918326212927085 1.0 1.0 25 Q13315,Q00534,P67809,P42771 4 +Positive regulation of protein tyrosine kinase activity 0.2718712740194027 0.1024206585255975 0.9184227867648432 1.0 1.0 5 Q13432,Q15334 2 +Regulation of substrate adhesion dependent cell spreading 0.3124719668159319 0.1024058388012863 0.918434549346274 1.0 1.0 17 Q14185,P60953,P50570,Q9P258,Q14155,Q13418 6 +Positive regulation of peptidyl serine phosphorylation 0.3121814858700563 0.1019132747981652 0.9188255130622144 1.0 1.0 17 Q16512,Q04637,P14174,Q99996,Q96N67 5 +Presynaptic endocytosis 0.2900203103870918 0.1017370799085844 0.9189653693210088 1.0 1.0 10 P50570,Q00535,O14976 3 +Dermatan sulfate proteoglycan metabolic process 0.2587287376902499 0.1012850382701696 0.9193241928436896 1.0 1.0 2 Q8NCH0 1 +Formation of extrachromosomal circular dna 0.2711988320376328 0.101270671343693 0.9193355973530816 1.0 1.0 5 P54132 1 +Epithelial tube formation 0.3270955669664691 0.1012221423667834 0.9193741199233938 1.0 1.0 23 P17612,P25440,P62081,P42574,Q92990,Q96Q89,Q9ULT8 7 +Microtubule based transport 0.3487811776533269 0.1009772074033457 0.9195685535381906 1.0 1.0 55 Q9UBF2,P78559,O14617,P27695,O60333,Q9P1Y5,P42858,Q9Y496,Q14204,P46821,Q9Y678,Q66K74,Q9NZ32 13 +Dendrite development 0.3520625952276123 0.1005604236631119 0.9198994147347952 1.0 1.0 50 P00492,Q9BRT6,P49841,P46109,Q08209,P18085,Q00535,Q6DN90,Q7L576,Q6SZW1,Q14999,P61160,P61586,Q9Y296,Q05086,O60678,Q9UQB8,P43034,P78559,Q06787,P60953,Q9H2U1,P46821,Q15334,O00401,Q66K74 26 +Heart development 0.228808691267188 0.1003529935275897 0.9200640870378688 1.0 1.0 94 Q15648,O75116,P21359,A1X283,Q9P2D1,Q99956,P20248,Q99873,P78527,Q9BQ70,Q92908,Q06124,P42345,P42574,Q13315,Q9ULT8,P62942,O75592,Q13464,P28482,Q6W2J9 21 +Substrate adhesion dependent cell spreading 0.3183803312026046 0.0987555528972097 0.9213323595627708 1.0 1.0 20 Q15058,Q14185,P50570,P46109,P60953,Q9P258,Q14155,Q13418 8 +Trna 3 end processing 0.2736779205258371 0.0987174366622141 0.9213626240354682 1.0 1.0 6 P05455,Q7L0Y3,Q99714,Q96Q11,Q9BQ52 5 +Muscle cell apoptotic process 0.3073301158551003 0.0986210458120106 0.9214391593390874 1.0 1.0 16 P26358 1 +Viral budding 0.2808018651607022 0.0981957580109321 0.921776850803648 1.0 1.0 8 Q8WUX9 1 +Regulation of postsynapse organization 0.3099154946956381 0.0981357918371598 0.9218244669075032 1.0 1.0 17 Q96QK1,P61160,Q05086,P18085,Q00535,Q9UQB8,P43034 7 +Negative regulation of mitotic cell cycle 0.335728258806938 0.0967339438069816 0.9229376829672672 1.0 1.0 63 O60921,O96017,Q9H6S0,P50748,Q92547,O43670,Q68E01,P61254,P14635,Q5JVF3,Q7Z7L1,Q13315,P53350,Q13564,P78527,Q9Y3I1 16 +Translational elongation 0.3304118712028849 0.0960841706916118 0.9234537230929688 1.0 1.0 26 O00178,Q05639,O60524,P13639,P63241,Q9BQC3,Q8N3C0,Q86UK7,O94822,P26641,Q9H2P9 11 +Cytokine production involved in immune response 0.2996173270447984 0.0958874383754863 0.9236099713309698 1.0 1.0 14 P14174,Q9UDY8 2 +Regulation of dendritic spine morphogenesis 0.296451070854681 0.0958640035414565 0.9236285838816254 1.0 1.0 13 P61160,Q05086,Q00535,Q9UQB8,P43034 5 +Fat cell differentiation 0.3370728416423816 0.0951965898663475 0.9241586785798082 1.0 1.0 30 Q8IXJ6,O96017,Q3SYG4,Q96EK7 4 +Rhythmic process 0.3329209096756469 0.0946720870502776 0.9245752896780708 1.0 1.0 64 Q9NRV9,P49841,P68400,P43490,O75116,O95352,Q93008,Q13330,P62136,Q00535,Q9BQG0,Q9Y5V3,P29375,P78527,Q06210,Q7Z6Z7,P42345,P42574,Q05086,O00429,O14744,O75592,Q00653,P04818 24 +Regulation of response to cytokine stimulus 0.3295300662459027 0.094646596987891 0.9245955368903264 1.0 1.0 26 Q06124,Q15648,Q9UIV1,Q01804,Q96BN8,Q14166,Q14790,Q9Y3Z3,P43034 9 +Meiotic chromosome segregation 0.3252252436441597 0.0944461581270574 0.924754750762071 1.0 1.0 24 O95347,Q15003,P61160,P46379,Q14674,Q15645,Q9NTJ3,Q13315,Q9BXW9,P53350,Q6IBW4,O43683 12 +Positive regulation of cell adhesion 0.3346353694059583 0.0944205778638261 0.9247750700565878 1.0 1.0 63 P49841,P31146,Q14185,P46109,Q08209,Q9HCL2,Q9HCM4,P20248,Q00534,O43290,Q06124,O00203,P50570,P55196,Q13315,Q9UDY8,Q14155,Q13418,P09429,O14617,Q13464,P60953 22 +Inner ear auditory receptor cell differentiation 0.2746563060370496 0.0941859279554554 0.9249614629442257 1.0 1.0 7 Q9UM54,Q14160,O95487,Q14651,O14745,P43034 6 +Regulation of mrna catabolic process 0.2956068365007266 0.0938820840623976 0.9252028258191748 1.0 1.0 78 Q9HCE1,P27695,Q5TAX3,Q14147,P67809,Q86TB9,O75116,Q96C86,Q86W50,Q9Y2L1,Q9Y2V2,Q6P6C2 12 +Positive regulation of double strand break repair 0.3174876710594306 0.0932427943761738 0.9257106774604448 1.0 1.0 21 Q96L91,Q9Y4A5,Q7Z4V5,P78527 4 +Regulation of actomyosin structure organization 0.3265311953359691 0.0931116140302075 0.925814890859846 1.0 1.0 25 Q16512,Q9H8V3,P63167,Q13464,P42345,O75116,P60953,Q7Z460,Q9Y613 9 +Ribosomal small subunit assembly 0.2945911787179077 0.0929094178239232 0.9259755237718176 1.0 1.0 13 P62841,P78527 2 +Negative regulation of erk1 and erk2 cascade 0.2975120597873781 0.0925485162085923 0.9262622462287332 1.0 1.0 14 Q96P70,Q14152,Q99956 3 +Regulation of cytosolic calcium ion concentration 0.3240130727519667 0.0925122423847703 0.9262910649173236 1.0 1.0 24 P09429,P27695,P17612,P31146,P42858,Q00535,Q9P2D1,Q15334,P62942 9 +Positive regulation of gliogenesis 0.2807676106601203 0.0923736653917483 0.9264011619259952 1.0 1.0 9 O14744,Q15382,P42345 3 +Pigmentation 0.2935301021604954 0.0912579367180363 0.9272876401088032 1.0 1.0 13 O14617,P21359 2 +T cell receptor signaling pathway 0.327398864122491 0.0912446551662356 0.9272981932254972 1.0 1.0 26 Q96EP0,P28482,P51452,P46109,P49770,Q13144,Q9UDY8 7 +Insulin receptor signaling pathway 0.3273551884795178 0.0911760046902403 0.927352741007462 1.0 1.0 26 Q06124,P49841,P43490,O00443,P31751,Q9Y5X3,P11802,Q9UQB8,O14654 9 +Regulation of gtpase activity 0.3405432024908852 0.0911737606154885 0.9273545240933652 1.0 1.0 58 P49841,P46109,Q13526,P31751,P21359,Q01968,Q9HAD4,Q9P2J5,Q9P258,P35241,Q9H8V3,Q8TC07,P42345,P55196,Q96N67,O95248,Q9P0V3,Q14155,Q15042,P46940,Q86X10,Q14684 22 +Purine nucleobase biosynthetic process 0.2797200342540019 0.0907457603314018 0.927694609118444 1.0 1.0 9 P00492,P07741,P49915 3 +Amino acid activation 0.3430231920597376 0.0903807788382006 0.9279846304384936 1.0 1.0 37 P47897,P49589,P26639,P07814,Q9BTE6,P41252,O43776,P23381,P54136,Q9NSD9,Q9P2J5,P26640 12 +Hair cell differentiation 0.2826971679075645 0.0899449405705328 0.9283309684457148 1.0 1.0 10 Q9UM54,P18074 2 +Regulation by virus of viral protein levels in host cell 0.2640382317801639 0.089666178526156 0.9285524932696724 1.0 1.0 5 O95793,Q16531,P42224,P63172 4 +Gmp metabolic process 0.3073172217001177 0.0896050864577656 0.9286010422609754 1.0 1.0 18 P00492,P07741,P31939,Q9P2T1,P49915,P12268,P20839,O15067 8 +Toll like receptor signaling pathway 0.2984230470718861 0.089236290740122 0.9288941245712424 1.0 1.0 15 P09429,Q01804 2 +Negative regulation of hormone secretion 0.2666192992194841 0.0875431153303168 0.9302398158806282 1.0 1.0 6 Q06124,P17858 2 +Negative regulation of peptide secretion 0.2666192992194841 0.0875431153303168 0.9302398158806282 1.0 1.0 6 Q06124,P17858 2 +External encapsulating structure organization 0.3181078564376225 0.0868695493785861 0.9307752040699632 1.0 1.0 23 P21359,Q9NPQ8,A1X283,Q9BPX3,P18074 5 +Cardiac ventricle development 0.3025162587818952 0.0865916710367339 0.9309960865826724 1.0 1.0 17 Q9P2D1,Q15648,P62942,Q9ULT8 4 +Tube morphogenesis 0.1721438600390709 0.0861799592711879 0.9313233616141156 1.0 1.0 114 Q15648,O75116,Q92990,P21359,Q9P2D1,Q9Y5V3,Q9HCM4,P78362,Q14999,P17612,P25440,P62081,P20248,Q96BN8,P40763,P67870,Q9GZT9,Q92908,P42574,O00443,Q96Q89,Q9ULT8,Q13418,Q16512,Q13464,P35579,P60953,P42785 28 +Endocytic recycling 0.3100161988294787 0.0856827296444721 0.931718631380288 1.0 1.0 20 Q96QK1,Q9UBQ0,Q9H4M9,O60826,Q9H223,O75436,Q5VIR6,Q9UID3,O60493,Q15036 10 +Positive regulation of ubiquitin dependent protein catabolic process 0.3337873096321709 0.0851765201191036 0.9321210569628372 1.0 1.0 32 O75925,O14965,P49841,O60826,Q8IXJ6,P53350,Q9ULT8,O75832 8 +Endosome organization 0.3232188850473205 0.0848666351606002 0.9323674173459848 1.0 1.0 26 Q8WUX9,Q9Y6D5,O75165,Q13501,Q2M389,Q99816 6 +Golgi organization 0.3353182676782629 0.083735079655371 0.9332670655437456 1.0 1.0 59 P36507,Q13190,Q14746,Q14999,P42858,Q7Z6Z7,P50570,Q53FT3,Q9P1Y5,Q92614,O14976,O14744,Q14155,P28482,P60953,Q96JB2,Q99996,Q99986,Q7Z460,Q92538,Q9UID3 21 +Endonucleolytic cleavage involved in rrna processing 0.2884088900047228 0.0836314910149405 0.9333494284259092 1.0 1.0 13 Q2NL82,O75818,O75691,Q5SY16,P78316 5 +Regulation of protein polymerization 0.3291616575533792 0.0834786656649146 0.9334709405065662 1.0 1.0 63 P31146,Q9Y2A7,Q7L576,Q14203,P35241,Q13045,Q96F07,P04350,P42345,Q9P1Y5,Q9Y295,P47755,Q9UQB8,Q9BPX3,Q14155,Q16512,Q14008,Q99996,Q7Z460,P46821,Q9BTW9 21 +Neural tube development 0.3236219830375745 0.0825738385147214 0.9341904040569564 1.0 1.0 27 P63167,P17612,P25440,P62081,P42574,Q13572,P21359,Q92990,Q96Q89,P07737,Q9ULT8 11 +Eye morphogenesis 0.2805859321565722 0.0818373296327147 0.9347760708653204 1.0 1.0 11 Q8NHU6,P21359 2 +Regulation of mitotic spindle assembly 0.280425801612343 0.0816120743352535 0.9349551993959092 1.0 1.0 11 Q8WUX9,P53350 2 +Regulation of neuron differentiation 0.3071377406942995 0.0815356065535023 0.935016009198326 1.0 1.0 20 Q9H8V3,Q15648,P49841,Q13464,Q04637,P26196,Q92974,P46821,O60271 9 +Growth 0.1724316682796106 0.0810215533731754 0.9354248117400568 1.0 1.0 191 O14681,Q15648,P49841,Q9BRT6,Q9Y263,Q93008,Q7Z4V5,P51532,P42771,Q00535,Q9P2D1,Q9HCL2,Q9ULC4,Q9HCM4,O14965,Q9UPN3,Q99956,P40763,Q96F07,P18074,Q14353,Q92908,Q06124,P42345,P50570,Q13315,O60271,Q9P0V3,O75832,O95067,Q04637,P60953,P46940,Q9P265,P46821,P04818,Q99816 37 +Erk1 and erk2 cascade 0.3358343193216554 0.0807551626270621 0.935636666592614 1.0 1.0 36 Q06124,P36507,P09429,P28482,P18615,P14174,P51452,P46109,Q96P70,P30046,Q99956,P49407,P20248,Q14152,O14744 15 +Negative regulation of ion transmembrane transporter activity 0.2795390892385875 0.0803745927702682 0.9359393335480908 1.0 1.0 11 Q06787,P28161,Q12955,Q9HD26,P62942 5 +Positive regulation of intracellular signal transduction 0.1761473428156871 0.0803184516552573 0.9359839833243984 1.0 1.0 157 O75569,P36507,Q96EP0,Q9Y3E0,O75116,Q13535,Q9P2J5,Q9Y5V3,P18615,P62081,P14174,P62841,P61927,Q99873,Q92499,Q06124,Q9H8V3,P60866,P49407,O00429,Q5JVF3,Q13315,O60271,Q9UDY8,P62942,O15111,Q14258,Q16512,O60826,P09429,Q13464,P29372,P30046,P22681,P60953,P61254,P63241,P46940 38 +Protein localization to cytoskeleton 0.3035823041209244 0.0802268200282885 0.9360568596098502 1.0 1.0 19 P78559,O14965,P49841,P29372,O60610,O15344,Q96Q89 7 +Regulation of translational initiation 0.3404762149605624 0.0801871624108407 0.9360884001943512 1.0 1.0 43 P41567,Q06787,Q04637,P42345,Q6PKG0,P40429,Q7Z478,P49770,Q13144,O43432,O60841,Q14240,Q92499 13 +Regulation of autophagy of mitochondrion 0.2977428686146338 0.0797724765109772 0.9364182151050164 1.0 1.0 17 P42858,Q9Y3I1 2 +Positive regulation of cell cell adhesion 0.3299868621879842 0.0795741055360712 0.936575990680883 1.0 1.0 32 Q06124,P09429,O14617,O00203,O43290,Q9UDY8,Q9HCL2 7 +Respiratory system development 0.3174690760283755 0.0795700441730807 0.9365792209369734 1.0 1.0 25 Q92908,P28482,Q9P2D1,O00203,P60953,Q53FT3,P62136,Q15185,Q9UPY5,A6NHR9 10 +Positive regulation of anion transport 0.2720363945131068 0.0795378320135813 0.9366048413197848 1.0 1.0 9 Q15042 1 +Positive regulation of cytoskeleton organization 0.3392125348736852 0.0793894776664916 0.9367228378311658 1.0 1.0 52 Q14203,Q9Y613,Q16512,Q14008,P42345,Q9UQB8,O75116,P60953,Q9Y295,Q99996,Q00535,Q14204,Q9Y2A7,Q7Z460,P46821,Q7L576,O00401,Q8WUW1 18 +Regulation of circadian rhythm 0.323104196196476 0.0791533599718173 0.9369106414907308 1.0 1.0 28 O75116,Q93008,O95352,P78527,Q9Y5V3 5 +Positive regulation of telomere maintenance 0.3211546912748544 0.0790622226080363 0.9369831314084442 1.0 1.0 27 Q13535,Q13315,Q96HR8 3 +Positive regulation of myeloid leukocyte mediated immunity 0.2600843208813507 0.0781808946144771 0.9376841593837796 1.0 1.0 6 Q9NY93,Q92499,Q9H2U1 3 +Response to light stimulus 0.3308594542351045 0.0781573582804454 0.9377028813743128 1.0 1.0 60 Q9UNS2,P09874,Q13432,Q13330,P31751,P62136,P30419,P21359,Q00535,Q13535,P28340,Q9UPY5,P52701,P10155,Q9NPQ8,Q15555,P18074,P42574,P50570,Q96RU2,P09884,Q13620,Q96K76,O60921,O96017,Q06787,P61254,P04035 28 +Regulation of actin filament bundle assembly 0.3162620079116563 0.0779006282197676 0.937907099684183 1.0 1.0 25 Q16512,P63167,Q13464,P42345,O75116,P35241,P60953,Q7Z460,Q9Y613 9 +Ribosome assembly 0.339273994913504 0.0773855652704877 0.9383168235914428 1.0 1.0 48 Q8IY37,P62841,P83731,P39023,Q02878,Q9NUL7,Q7Z478,P27635,P78527 9 +Response to purine containing compound 0.3040858194637545 0.0773303765608159 0.9383607262517206 1.0 1.0 20 P27695,Q96RD7 2 +Nad metabolic process 0.2898845465543879 0.0770717206254056 0.938566489738646 1.0 1.0 15 P85037,P17858 2 +Positive regulation of calcium ion transport 0.295641608908558 0.0769229128726334 0.9386848697134058 1.0 1.0 17 P42858 1 +Regulation of protein localization 0.1702445255684647 0.0768019290278239 0.9387811161310876 1.0 1.0 227 Q96EP0,P49841,P09874,O75116,P46109,Q08209,Q13526,P30419,P21359,P31751,O95071,Q00535,Q4G0J3,Q9UPY5,Q9Y5K6,Q96D46,Q9Y5V3,Q9HCM4,O14980,P17612,P35241,P22059,P53985,Q9Y6B6,Q6GQQ9,Q06124,Q9H8V3,Q7Z6Z7,P55196,Q92614,O00429,Q00610,Q96Q89,P19784,O95486,Q9ULT8,P31689,Q13501,Q7L2J0,P20290,P62942,P17858,Q14258,P78559,O75592,P35580,P60953,P40818,Q92538,Q7Z5K2,P53350,P08237,P04035,Q15334,O00401,O00410,Q99816 57 +Pallium development 0.334641599910906 0.0762067495100401 0.9392546129746018 1.0 1.0 38 Q9H0D6,P49841,Q15058,P31939,P42574,P46109,P21359,Q13144,O43776,Q00535,P61586,P19784,Q00534,Q96P11 14 +Dna methylation 0.3005557782925752 0.0761213144631 0.9393225828480508 1.0 1.0 19 Q9NRZ9,P09874,Q9UIF9,Q8NB78,P26358,O14744 6 +Negative regulation of cell cycle phase transition 0.3031541605723991 0.076092034623635 0.9393458772189878 1.0 1.0 73 Q06124,O60921,O96017,P50748,Q92547,O43670,Q68E01,P61254,Q96RU2,P14635,Q13535,Q5JVF3,Q13315,Q7Z7L1,P53350,Q13564,P78527,Q9Y3I1 18 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.3240475759176087 0.0756319290235492 0.9397119335190884 1.0 1.0 30 O75925,O14965,P49841,Q8IXJ6,P53350,Q9ULT8,O75832 7 +Regulation of phospholipid biosynthetic process 0.2541630041479886 0.0755381881490486 0.939786514566434 1.0 1.0 5 P17655 1 +Cellular amino acid biosynthetic process 0.3285058052727761 0.0755145658367488 0.9398053087649444 1.0 1.0 33 P00374,Q13126 2 +Regulation of small gtpase mediated signal transduction 0.3363168196805758 0.0746645850837256 0.9404815859986322 1.0 1.0 42 Q9H8V3,P63167,Q13618,P22681,P50570,P35241,P49407,Q92974,P21359,Q6XZF7,Q92538,Q86X10,Q6DN90,Q13501,Q9Y6D5,Q9Y5K6 16 +Regulation of ras protein signal transduction 0.3262038127808223 0.0743157099675306 0.9407591768511836 1.0 1.0 32 P63167,Q13618,P22681,P50570,P35241,P49407,Q92974,P21359,Q92538,Q6DN90,Q13501,Q9Y6D5 12 +Intracellular transport of virus 0.2571687666652665 0.0743004712286732 0.9407713020834894 1.0 1.0 6 Q06787,P63172 2 +Vesicle localization 0.329848342083505 0.0742351536480802 0.9408232744425804 1.0 1.0 59 Q9UM54,O43795,Q99816,Q92905,Q00535,P42858,Q9Y496,Q14204,Q9Y6B6,O94832,Q9BZH6,O00203,P50570,P43034,O14617,P27695,Q7Z460,Q92538,O00401,Q13618,O00743 21 +Positive regulation of erk1 and erk2 cascade 0.2905553755281516 0.0740454762575213 0.9409741997312432 1.0 1.0 16 P14174,P09429,P49407,P30046 4 +Positive regulation of locomotion 0.2402343377422636 0.0738003762994092 0.9411692275999866 1.0 1.0 90 P31146,Q9Y263,Q14185,O75116,P46109,Q08209,P31751,Q6DN90,Q9HCM4,P35241,O60610,P20248,P40763,Q9UH99,P31949,P61586,Q96QK1,P42345,Q9H9T3,O00443,O00429,Q96N67,Q96Q89,Q13315,O60271,Q14155,Q16512,P09429,P28482,Q92974,Q7Z460 31 +Tube formation 0.3131069705847084 0.0736822795665483 0.941263199313198 1.0 1.0 25 P17612,P25440,P62081,P42574,Q92990,Q96Q89,Q9ULT8 7 +Rna dependent dna biosynthetic process 0.3349122216484839 0.0734493106544161 0.9414485793002012 1.0 1.0 41 Q8IZH2,P35251,Q13535,Q13315,Q96HR8 5 +Cerebral cortex development 0.3142889394956425 0.0725109486392553 0.9421952926523444 1.0 1.0 26 P49841,Q15058,P31939,P46109,P21359,Q00535,O43776,P61586,P19784,Q96P11 10 +Ear development 0.3116951247981702 0.0718617721281604 0.9427119127833938 1.0 1.0 25 Q9UM54,O75569,Q06124,P28482,Q9Y4P1,Q9P2D1 6 +Regulation of intracellular estrogen receptor signaling pathway 0.2915979544552024 0.0716954616090192 0.942844267980989 1.0 1.0 17 Q16512,Q15648,P09874,A5YKK6,Q13309 5 +Negative regulation of ubiquitin protein transferase activity 0.2786842667179034 0.0706765192367537 0.943655209028284 1.0 1.0 13 P62081,P46777,P62841,P60866 4 +Ventricular septum development 0.2651076662628395 0.0705058864891843 0.943791015471328 1.0 1.0 9 Q9ULT8 1 +Cellular response to peptide hormone stimulus 0.3248407780796708 0.0703927667897824 0.943881048234364 1.0 1.0 61 P07741,P49841,P09874,P43490,O75116,P31751,Q8TBX8,Q7L576,P07814,P20248,P40763,P78527,O14654,Q06124,O00443,P11802,Q9UQB8,P27695,Q13464,P46821,Q9Y5X3 21 +Positive regulation of protein secretion 0.3081784138314949 0.0701807812388051 0.9440497709525668 1.0 1.0 24 Q96QK1,P35580,Q92614,O00429,P22059,O95486,P08237,Q9Y5K6 8 +Pyrimidine containing compound metabolic process 0.3100560943757776 0.0697996695974407 0.9443531101611662 1.0 1.0 25 P28482,P42345,P15531,P17812,P04183,P27708,Q9BPU6 7 +Transcription elongation from rna polymerase ii promoter 0.3241924342500479 0.0697895043816908 0.9443612010992216 1.0 1.0 33 Q7KZ85,P18615,Q14241,Q9Y5B9,Q8IXH7,O75909,Q5JVF3,Q9NYV4,Q4G0J3,Q9H3P2,Q14004,Q9GZS3 12 +Positive regulation of cell cycle process 0.2714102990249879 0.0697283921963351 0.9444098430708056 1.0 1.0 82 Q15648,Q15398,P23921,O75116,Q96DE0,Q9P258,O14965,Q15058,P35241,Q14204,P61586,Q99741,Q9H8V3,P30307,Q96QE3,Q9UJX5,Q8IXJ6,Q96Q89,Q16513,P14635,Q5JVF3,P11802,Q7L2J0,O96017,P27695,Q04637,P60953,Q14674,Q13618 29 +Regulation of leukocyte chemotaxis 0.2865921232443493 0.0690997325235205 0.9449102339365444 1.0 1.0 16 P09429,P28482,P30046 3 +Response to nutrient 0.3219353686723017 0.0687541010814411 0.945185353613933 1.0 1.0 32 Q15648,P42345,P61803,P50747,P53985,P35573,Q96C86,P46821,Q14258 9 +Pattern specification process 0.3228464044374725 0.0680845357916965 0.9457183404402344 1.0 1.0 33 Q9HCM4,O75569,O14965,Q12830,P17612,P29372,P46109,Q9Y673,Q8NHU6,Q13315,Q10567,Q6W2J9,P78527 13 +T cell proliferation 0.3124403889175692 0.0676922234516459 0.946030639899646 1.0 1.0 27 P09429,P42574,P62753,Q9UDY8,Q9HCL2 5 +Lamellipodium assembly 0.2989233320030496 0.0675602975973516 0.9461356610798404 1.0 1.0 21 P42345,P50570,P60953,Q9Y2A7,Q7L576,Q8WUW1,Q14155 7 +Regulation of type i interferon mediated signaling pathway 0.2758989529678139 0.0673216279446077 0.9463256593358028 1.0 1.0 13 Q06124,Q9Y3Z3,Q9UIV1 3 +Positive regulation of dendrite morphogenesis 0.2655533593111984 0.0668601593503384 0.9466930302653048 1.0 1.0 10 Q9UQB8,Q14999,P61160,P43034 4 +Vesicle mediated transport to the plasma membrane 0.3314293469528671 0.0668089377417825 0.94673380801997 1.0 1.0 44 Q15036,Q4J6C6,Q9Y6D5,Q9UBQ0,Q9UPN3,O75436,Q96QK1,Q96KP1,Q9H4M9,P50570,O60493,P63244,O60826,O15027,Q9H223,Q8TAG9,Q5VIR6,Q9HD26,Q9UID3,Q15334 20 +Spermatid differentiation 0.3002071972665635 0.0661689843859654 0.9472432895147024 1.0 1.0 22 O95248,Q14997 2 +Developmental growth involved in morphogenesis 0.3305321884415061 0.0661432902529071 0.9472637456532362 1.0 1.0 43 Q9HCM4,Q15648,Q9BRT6,O14965,Q9UPN3,Q9Y263,P50570,Q93008,O60271,P46940,Q00535,Q9P265,P46821,Q96F07 14 +Muscle adaptation 0.2865017560773792 0.0655758261229 0.9477155356367524 1.0 1.0 17 Q92908,O75116,Q13555,P09874 4 +Regulation of viral genome replication 0.3144157257563939 0.0655669226120408 0.9477226243548668 1.0 1.0 29 Q6PKG0,P78362,Q9UIV1,Q96SB4 4 +Transcytosis 0.2496569108708962 0.0651169643095235 0.9480808735326332 1.0 1.0 6 Q00610 1 +Lysosomal transport 0.3230075039880121 0.0650544188415222 0.9481306720072732 1.0 1.0 35 Q9H269,O14617,P20645,Q7Z3T8,Q8WUX9,Q9UGU5,Q9UID3,Q9P2R3,Q99816 9 +Regulation of cell cycle checkpoint 0.2792923138426096 0.0640704601455311 0.9489141228924844 1.0 1.0 15 O96017,Q5JVF3,P14635 3 +Protein deneddylation 0.2522414823669981 0.0638370422472778 0.9490999829489156 1.0 1.0 7 Q7L5N1,Q9UNS2,Q9BT78,Q13098,Q92905,P61201 6 +Tissue morphogenesis 0.2879695524178913 0.0632837846540019 0.9495405278513204 1.0 1.0 76 Q15648,P62136,Q92990,Q9P2D1,Q9Y5V3,Q9HCM4,P17612,P25440,P62081,P20248,P61586,P67870,P42345,P42574,Q16881,Q9P1Y5,Q9Y696,Q96Q89,Q9ULT8,P06744,P62942,Q13418,Q16512,P63167,P60953,Q7Z460 26 +Positive regulation of cellular amide metabolic process 0.3095775026657876 0.0623471538948508 0.9502863781118124 1.0 1.0 67 O15371,Q06787,P67809,P42345,P42574,O75116,Q04637,Q6PKG0,P61254,P20248,Q7Z478,P63241,Q13144,P62701,P46777,Q96P11,P78527 17 +Detection of abiotic stimulus 0.2537741546452288 0.0615245667672814 0.9509414500121228 1.0 1.0 8 O96017 1 +Positive regulation of response to dna damage stimulus 0.3270637356456002 0.0612802610642444 0.9511360106425516 1.0 1.0 44 P09429,Q99504,Q96L91,Q7Z4V5,Q13535,Q13315,Q9Y4A5,P78527 8 +Positive regulation of double strand break repair via homologous recombination 0.2849204298308191 0.0606974775319922 0.9516001406167602 1.0 1.0 18 Q96L91,Q9Y4A5,Q7Z4V5 3 +Tube development 0.1715749568920274 0.060630589623682 0.9516534113344082 1.0 1.0 142 Q15648,O75116,Q92990,P21359,Q9UPY5,Q9P2D1,Q9Y5V3,Q9HCM4,P78362,Q14999,P17612,P25440,P62081,P20248,Q96BN8,P40763,P67870,Q9GZT9,Q92908,P42574,O00203,Q53FT3,O00443,Q15185,Q96Q89,Q9ULT8,Q9HCK8,Q13418,Q16512,Q13464,P28482,P35579,P60953,P42785,P04818 35 +Regulation of endocytosis 0.3266760346362268 0.0604188862022168 0.951822017120496 1.0 1.0 45 Q06787,Q13464,Q7Z3T8,Q96T51,P22681,P50570,P49407,Q13614,Q9H223,Q9P2R3,Q15334,Q9UL63,Q9Y5K6,Q99816 14 +Regulation of leukocyte apoptotic process 0.2728489718867847 0.0603934664301772 0.9518422621942436 1.0 1.0 14 P14174,Q9HCL2,P42771 3 +Regulation of muscle adaptation 0.2756036888658029 0.060058507531543 0.9521090364699756 1.0 1.0 15 O75116,Q13555,P09874 3 +Protein monoubiquitination 0.2970300335650365 0.0599495862845664 0.9521957867390318 1.0 1.0 23 Q13616,Q7Z6Z7,Q99816,P22681,Q86UK7,Q6W2J9,Q14258 7 +Regulation of calcium ion transmembrane transport 0.2941960559003064 0.0594772692799178 0.9525719699062136 1.0 1.0 22 P27695,Q06787,P17612,P31146,P42858,Q00535,Q9P2D1,P62942 8 +Mammary gland development 0.291398903255384 0.0591414498912985 0.9528394441626742 1.0 1.0 21 O75592,P28482,P15531,P31751,P49327 5 +Regulation of dna templated transcription in response to stress 0.2715945986260015 0.0590810387247728 0.9528875611625148 1.0 1.0 14 Q92616 1 +Response to mechanical stimulus 0.3003378796004826 0.0586707978163674 0.953214319223407 1.0 1.0 25 P46821,P42858,Q9UKL3 3 +Cellular response to light stimulus 0.3044211772787601 0.0585879206442908 0.953280332085512 1.0 1.0 27 P09874,P30419,P31751,P61254,Q96RU2,Q13535,P28340 7 +Ras protein signal transduction 0.2934722607442093 0.058498154688761 0.9533518323245193 1.0 1.0 73 O75116,P46109,P42771,P21359,Q9Y2A7,P26358,Q6DN90,Q7L576,Q9Y6D5,Q15058,P35241,P20248,Q8WUW1,P50570,P49407,Q96RU2,Q13501,Q15047,P63167,Q13464,P22681,P60953,P40818,Q92974,Q92538,Q13618 26 +Response to camp 0.2638014934531629 0.0576499659518108 0.954027448750238 1.0 1.0 12 Q92908,P27695 2 +Negative regulation of response to stimulus 0.1667614600038635 0.0573665831304641 0.9542531819460434 1.0 1.0 249 Q9UIV1,P67809,Q99504,A5YKK6,P21359,O95071,Q9Y5K6,P49427,P14174,P51452,P42858,Q01804,Q99956,Q96BN8,Q9UBB9,Q00534,Q6GQQ9,P42345,Q96P70,P50570,P49407,Q8IXJ6,P19784,Q13315,Q96FW1,Q9P0V3,P62942,Q9NR09,Q9HCK8,O96017,O60826,P22681,P30046,Q9UGU5,Q7Z460,Q14152,P04035,O95881,Q99816 39 +Regulation of phagocytosis 0.2697133829847848 0.0571673189623015 0.9544119112588852 1.0 1.0 14 Q9NT62,P09429,Q92614 3 +Neuron projection extension 0.3183343876814783 0.0570596758272553 0.95449765808926 1.0 1.0 37 O14965,Q9BRT6,Q9UPN3,Q9Y263,P50570,Q93008,O60271,P46940,Q00535,Q9P265,P46821,Q96F07 12 +Positive regulation of epidermis development 0.2492401250894406 0.0568246439414021 0.9546848826263584 1.0 1.0 8 P22392 1 +Positive regulation of epidermal cell differentiation 0.2492401250894406 0.0568246439414021 0.9546848826263584 1.0 1.0 8 P22392 1 +Placenta development 0.3006504450567988 0.0567884517811596 0.9547137132367304 1.0 1.0 26 Q15648,Q14999,P28482,P62753,Q9ULT8,Q9NR09 6 +Cortical actin cytoskeleton organization 0.2913290088683243 0.0565258019326158 0.9549229414111816 1.0 1.0 22 Q13464,O75116,Q00535,Q9Y2A7,Q9Y613,Q15334 6 +Rna surveillance 0.2618677388700967 0.0557352000842069 0.9555527574618374 1.0 1.0 12 Q8IZH2 1 +Regulation of dendrite development 0.2827843260160954 0.0557046193077835 0.9555771195432544 1.0 1.0 19 P49841,Q14999,P61160,Q9UQB8,P46109,Q08209,Q9H2U1,P61586,Q7L576,P43034 10 +Protein localization to condensed chromosome 0.2617449269301683 0.0556158863915333 0.955647808582714 1.0 1.0 12 P50748 1 +Negative regulation of response to dna damage stimulus 0.3030814046897407 0.0552006071460674 0.9559786452422564 1.0 1.0 28 O96017,Q96QE3,Q15554,P14174,O75832,O95071,Q9UBB9,Q9BRJ7,Q96FW1,A6NHR9,Q96QC0 11 +Regulation of dna binding 0.3010682360609624 0.0551469270767996 0.9560214105992156 1.0 1.0 27 P09429,P15531,Q8IXJ6,P67870,P18074 5 +Negative regulation of neuron projection development 0.2846031518005844 0.0548851245253679 0.95622998292391 1.0 1.0 20 P10589,Q00535,P61586,Q9P265,O14976,P43034 6 +Regulation of epithelial cell differentiation 0.279085286128666 0.0547780436514502 0.9563152927613624 1.0 1.0 18 P22392,Q15648,O75116 3 +Vesicle targeting to from or within golgi 0.2641077931712652 0.0547736788118652 0.95631877017875 1.0 1.0 13 Q9Y6B6 1 +Ribosomal small subunit biogenesis 0.3193966772979188 0.0540591149089174 0.9568880661644754 1.0 1.0 55 Q2NL82,P08708,P62847,P62081,Q8IY37,P62841,O75818,P62851,P62753,P62241,P78316,P18074,P78527 13 +Histone h3 k4 trimethylation 0.2497199723331288 0.053860458119058 0.9570463407611428 1.0 1.0 9 P16402,Q6UXN9 2 +Regulation of receptor mediated endocytosis 0.295520882895357 0.0538207465339276 0.9570779801302844 1.0 1.0 25 Q06787,P22681,P50570,P49407,Q13614,Q8IYB5,Q15334,O00401,Q9UL63,Q9Y5K6 10 +Positive regulation of proteolysis 0.2319914941457604 0.0537796360931641 0.95711073407943 1.0 1.0 90 O75116,P49327,Q9UKL3,O14965,Q14997,P20248,P40763,Q96F07,Q8IXJ6,Q9ULT8,Q15020,Q9UDY8,O75832,O75925,O60826,P09429,Q06787,P35579,P61289,P53350 20 +Antigen receptor mediated signaling pathway 0.299395887749964 0.0535081285258511 0.957327054302155 1.0 1.0 27 Q9UDY8,Q96EP0,P28482,Q13144 4 +Nuclear membrane reassembly 0.2527753522168768 0.0534712648157734 0.9573564252399148 1.0 1.0 10 Q8IXJ6,Q8WUX9,Q9H6H4 3 +Cell cycle checkpoint signaling 0.3098978106834656 0.0529540618593085 0.9577685096493528 1.0 1.0 63 Q92547,Q5TBB1,O43670,P54132,Q13535,P50748,Q68E01,Q08J23,Q13564,P78527,Q06124,Q969U7,Q96RU2,P14635,Q5JVF3,Q13315,O60921,O96017,P61254,Q99459,Q9H900,P53350 22 +Negative regulation of cell cycle g2 m phase transition 0.2922389597490461 0.0528228541899294 0.9578730519084128 1.0 1.0 24 O60921,Q92547,Q68E01,P54132,Q13315,P53350,Q13564 7 +Protein peptidyl prolyl isomerization 0.298345371130674 0.0525045420520113 0.9581266762945368 1.0 1.0 27 Q9Y237,O00170,Q15257,Q96BP3,P62942 5 +Response to uv 0.3146021851327762 0.0520982465827391 0.9584504100949136 1.0 1.0 38 O60921,P52701,P09874,P42574,Q96RU2,Q13535,P28340,P18074 8 +Gliogenesis 0.3191713931636983 0.0520167915022889 0.9585153138422768 1.0 1.0 52 P46109,P31751,P21359,Q00535,Q13144,P49770,P40763,P61586,Q00534,Q96P11,P18074,Q06124,P42345,Q8TEW0,Q8IXJ6,O14744,P43034,Q13418,P28482 19 +Presynapse organization 0.2327318375638514 0.0518185504988946 0.9586732742476664 1.0 1.0 5 Q04637 1 +Double strand break repair via nonhomologous end joining 0.2975885043119176 0.0517937096908311 0.9586930677654028 1.0 1.0 27 P49917,P09429,P61160,Q96FZ2,Q9UBB9,Q13315,P78527,O00487,A6NHR9,Q9BRJ7 10 +Aspartate family amino acid metabolic process 0.2863561132914279 0.0517594290472776 0.9587203831233924 1.0 1.0 22 Q13126 1 +Mitochondrial fission 0.2606803433097464 0.0516035378209263 0.9588446003245504 1.0 1.0 13 Q96QK1,O14965,Q9UDX5,O00203,O00429 5 +Cellular response to mechanical stimulus 0.2605591117381759 0.0514951604517252 0.9589309581370384 1.0 1.0 13 Q9UKL3 1 +Positive regulation of muscle cell differentiation 0.2573071517179429 0.0514845029005192 0.958939450367824 1.0 1.0 12 Q14012,P42345,P32929,Q9UGN5,Q86TU7 5 +Peptidyl tyrosine modification 0.3139730564405154 0.0514749796329336 0.9589470387740744 1.0 1.0 38 Q06124,P36507,Q9UIV1,P22681,P42345,Q13432,P14174,Q9UIG0,Q92974,Q9H223,P22059,P49761,Q86XI2,Q15334,Q92796,Q99816 16 +Telomere maintenance via telomere lengthening 0.3180623894096078 0.0512077936184525 0.9591599415849644 1.0 1.0 44 P28482,Q8IZH2,P35251,Q13535,Q13315,Q96HR8 6 +Regulation of cell cycle g2 m phase transition 0.316150234949008 0.0510460975150802 0.9592887878993012 1.0 1.0 41 O60921,O14965,P30307,Q15058,Q96QE3,P23921,Q92547,Q5TBB1,Q68E01,P54132,P14635,Q13564,Q13315,P53350,P11802,Q9P258 16 +Autophagy of mitochondrion 0.3077213599457238 0.0500946997084413 0.9600469234570406 1.0 1.0 34 Q9NT62,Q7Z6Z7,Q9Y4P1,P50851,P42858,P19784,Q13501,Q9Y3I1 8 +Vesicle mediated transport between endosomal compartments 0.2810615821818809 0.0492778285089563 0.96069788833449 1.0 1.0 21 P36507,O94832,P28482,P35241,Q13614,Q99570,O75165 7 +Positive regulation of mitotic cell cycle phase transition 0.3100824907690256 0.0487796466956208 0.96109490244619 1.0 1.0 37 P30307,P27695,Q15398,P23921,Q04637,Q9UJX5,Q13618,P35241,Q14674,P14635,P11802,Q9P258,Q7L2J0,Q99741 14 +Cellular response to chemical stress 0.2495836313985359 0.0486671346335651 0.9611845675890444 1.0 1.0 85 P00374,O75569,P27695,P28482,P09874,P42574,O95352,Q8IXJ6,Q9BYN0,Q13315,O15111,Q9Y3I1 12 +Positive regulation of immune system process 0.1651277609470765 0.048558571328004 0.9612710862830582 1.0 1.0 121 Q15648,Q96EP0,Q13144,Q9BUI4,Q96FZ2,Q9HCL2,P14174,P51452,O43290,P78527,Q92499,Q06124,P55212,O00203,Q92614,Q5JVF3,Q9UDY8,Q16512,P09429,O14617,P28482,Q9NW08 22 +Positive regulation of dna repair 0.306010234640066 0.0485240918440101 0.9612985645389532 1.0 1.0 34 P09429,Q99504,Q96L91,Q7Z4V5,Q9Y4A5,P78527 6 +Fc receptor signaling pathway 0.2363854512409201 0.0484093952681285 0.9613899717439888 1.0 1.0 7 Q16512,P19174 2 +Positive regulation of cell morphogenesis involved in differentiation 0.289479957612012 0.0483241043724438 0.9614579444805408 1.0 1.0 25 Q14999,Q14185,P50570,P46109,P60953,P43034,Q9UQB8,P78527,Q14155,Q13418 10 +Regulation of cell division 0.3106208339408605 0.0482806273322047 0.9614925936957452 1.0 1.0 38 O14965,Q9H8V3,Q15058,P67809,P60953,Q13526,P54132,Q8IXJ6,Q96Q89,Q16513,Q99570,P61586,P53350,Q13618,Q9NR09 15 +Regulation of lipid localization 0.2867944654364701 0.0479575743151317 0.9617500544681654 1.0 1.0 24 P07814,P14174,P31751,Q9BZF3,Q9Y6B6 5 +Positive regulation of b cell mediated immunity 0.2429858905070697 0.0479434366189881 0.9617613217570328 1.0 1.0 9 Q96FZ2 1 +Positive regulation of isotype switching 0.2429858905070697 0.0479434366189881 0.9617613217570328 1.0 1.0 9 Q96FZ2 1 +Response to heat 0.3127582632788926 0.0477751245793551 0.9618954616222908 1.0 1.0 41 Q99543,P49841,Q9UHD1,P17612,P42345,Q53FT3,O60884,P21359,P49770,Q13144,Q13535,Q13315,P31689,Q9UER7 14 +Dsrna processing 0.281678625020861 0.0476685217024609 0.9619804216139908 1.0 1.0 22 Q8IWR0,O75569 2 +Regulation of gene expression epigenetic 0.3151957708664971 0.0474213753203988 0.962177393140886 1.0 1.0 47 Q8IXJ6,P41567,P26358 3 +Positive regulation of dna templated transcription initiation 0.2521959550489063 0.0471465746778018 0.962396407360145 1.0 1.0 12 Q86VP6,Q15648,Q9Y2X0 3 +Dna templated transcription initiation 0.3127783574643957 0.0471348196319226 0.9624057761141432 1.0 1.0 42 Q86VP6,Q15648,P09429,Q9ULK4,Q14241,Q9Y6J9,P51532,Q9UIF9,Q12789,O60244,Q9Y2X0,Q15369,P11802 13 +Cell cell signaling by wnt 0.3003775997664049 0.0470999029162283 0.962433604714974 1.0 1.0 66 Q70CQ2,P49841,P68400,Q13526,P62136,P51532,O95071,Q9GZS3,Q9UPN3,Q96BN8,P61586,P67870,Q7KZI7,P19784,Q13418,Q9HCK8,P60953,P40818,Q9UGU5,Q13618 20 +Post embryonic development 0.2616143487941331 0.0470802578448406 0.9624492618448504 1.0 1.0 15 O15357,P18074,Q13315,P42345 4 +Dna unwinding involved in dna replication 0.2642429207956397 0.0467730493084262 0.9626941090532262 1.0 1.0 16 P17096,P46063,P54132,P33991,P33993,P33992 6 +Protein localization to cell surface 0.2611126986477369 0.0466768842444982 0.962770753960867 1.0 1.0 15 P78559,Q92538 2 +Response to transforming growth factor beta 0.2992476239688126 0.0466662709758153 0.9627792129062795 1.0 1.0 31 Q9HCM4,Q13464,P09874,O75116,Q93008,P46109,P50570,P40763,P62942 9 +Regulation of wnt signaling pathway 0.3145488714730585 0.0466246265613778 0.9628124042131644 1.0 1.0 49 Q96QK1,Q70CQ2,P49841,P98170,P68400,Q9UPN3,P40818,Q13526,P62136,P51532,Q96BN8,O95071,Q9UGU5,O60493,P63244,Q9HCK8,Q13418 17 +Regulation of lymphocyte activation 0.3079496013766019 0.0460717600040443 0.9632530543511684 1.0 1.0 60 Q06124,Q16512,P09429,O14617,P14174,P51452,O00203,P42574,O43290,Q5JVF3,Q13315,Q9UDY8,Q96FZ2,Q9HCL2,P78527,Q9Y3I1 16 +Secondary metabolic process 0.2471724785812868 0.0457991930913554 0.9634703019573538 1.0 1.0 11 O75592,P30046 2 +Regulation of cytoplasmic transport 0.2559499720575957 0.0450556964835435 0.9640629146191536 1.0 1.0 14 O75165,P36507,P28482,Q13614 4 +Regulation of neurotransmitter transport 0.26468172864847 0.0448164712405934 0.9642535961324072 1.0 1.0 17 P49841,Q06787,Q15042,P21359,Q00535 5 +Gtp metabolic process 0.2491801095733195 0.0447889637949515 0.9642755218819472 1.0 1.0 12 P22392,O00178,P15531,P61586,P20839 5 +Regulation of multicellular organism growth 0.2611345164594997 0.0443526010447123 0.964623343325726 1.0 1.0 16 Q9P2D1,P40763,Q9HCL2,Q14353 4 +Negative regulation of protein localization 0.3085657579311722 0.0434001141003464 0.9653825867495324 1.0 1.0 42 Q06124,P78559,P49841,Q6GQQ9,O75116,Q08209,Q00610,P21359,Q00535,Q16850,Q9ULT8,P04035,P31689,P17858,P20290,Q9Y5V3 16 +Rho protein signal transduction 0.2783882196348543 0.0431389710430924 0.9655907538005192 1.0 1.0 23 P63167,Q13464,O75116,P60953,P49407,Q92974,Q13618 7 +Negative regulation of mrna 3 end processing 0.2295277943813462 0.0430981965057696 0.9656232569451496 1.0 1.0 7 P18615,O00267,Q5VTR2,Q6PD62,Q6PJT7,O75150 6 +Actin filament depolymerization 0.2702609163919119 0.0427558371959647 0.9658961685844184 1.0 1.0 20 Q9UHB6,P35241,Q9BPX3,P47755 4 +Viral genome replication 0.3098855589386922 0.0423156163932367 0.9662470963550772 1.0 1.0 50 P78362,Q9UIV1,Q06787,O75116,Q6PKG0,P42356,Q16513,O75909,Q96SB4,Q9H6S0 10 +Glycerophospholipid biosynthetic process 0.3077735736836642 0.0417119588601194 0.9667283204676044 1.0 1.0 44 O96017,P35790,O00443,P42356,Q01968,Q08AM6,Q13315,Q8NCE2 8 +Positive regulation of cell activation 0.3077142326650821 0.0416629799659327 0.966767366028764 1.0 1.0 44 Q06124,P09429,O14617,P14174,O00203,O43290,Q5JVF3,Q9UDY8,Q96FZ2,Q9HCL2,P78527 11 +Cardiac chamber development 0.2685822881480276 0.041552254447269 0.9668556357714536 1.0 1.0 20 Q15648,P20248,Q9ULT8,Q9P2D1,P62942 5 +Gland morphogenesis 0.2413687783020383 0.041549842007784 0.9668575589587742 1.0 1.0 11 P60953,Q15648,Q15418 3 +Protein localization to cell junction 0.2681936763466186 0.041279667540897 0.967072942204023 1.0 1.0 20 Q9UQB8,Q9Y496,Q15334,P78559 4 +Actin filament based movement 0.286531820519469 0.0410322111119545 0.9672702167239676 1.0 1.0 28 Q9UM54,Q9HCM4,O94832,P35580,Q13464,P35579,Q99996,Q9UH99,O00401 9 +Somatic diversification of immunoglobulins 0.2673154101126125 0.0406718945018446 0.9675574679871766 1.0 1.0 20 P49917,P52701,Q96QE3,P20585,Q96FZ2,P78527 6 +Regulation of canonical wnt signaling pathway 0.3021073936977918 0.0402746874861484 0.9678741338609488 1.0 1.0 39 Q70CQ2,Q9HCK8 2 +Vacuolar transport 0.302898426719413 0.0401408650395373 0.9679808224501758 1.0 1.0 40 Q9H269,O14617,P20645,Q7Z3T8,O00203,Q8WUX9,Q9UGU5,Q9UID3,Q9P2R3,Q99816 10 +Positive regulation of dendritic spine morphogenesis 0.2287713896587674 0.0400979591327539 0.9680150288709156 1.0 1.0 8 Q9UQB8,P61160,P43034 3 +Spliceosomal snrnp assembly 0.2740717782858106 0.0400588677831869 0.9680461942150178 1.0 1.0 23 O43290,P62314,P57678,Q9Y312 4 +Cytosolic calcium ion transport 0.2809770984468985 0.0400562225401325 0.968048303120949 1.0 1.0 26 Q9P2D1,P27695,P42858,Q9NWR8 4 +Regulation of secretion 0.2070010197257767 0.0397781403627615 0.9682700038988716 1.0 1.0 94 Q9UM54,P49841,Q08209,P21359,Q00535,Q16850,Q9P2D1,Q9Y5K6,P14174,P22059,P53985,Q06124,Q92614,O00429,O95486,P17858,O75592,P27695,Q06787,P35580,P08237,Q15042,Q7Z460,Q9Y5X3,P04035,Q15334,Q99816 27 +Lymphocyte activation involved in immune response 0.2865119685166524 0.0396329592923332 0.9683857503584932 1.0 1.0 29 P49917,P52701,P09429,P42345,P40763,P62753,Q9UDY8,Q96FZ2 8 +Regionalization 0.2751416841485454 0.0391697015447998 0.9687550897551098 1.0 1.0 24 Q9HCM4,O14965,Q12830,P17612,Q8NHU6,Q13315,P78527 7 +Leukocyte proliferation 0.3032396401221723 0.0391350547078047 0.9687827127515458 1.0 1.0 42 Q16512,P00492,Q9NRZ9,Q96QE3,P09429,P28482,P14174,P42574,P17812,Q92990,P62753,Q13315,Q9UDY8,Q9HCL2 14 +Positive regulation of myeloid cell differentiation 0.2591693748889101 0.0389262322143698 0.9689492021321716 1.0 1.0 18 Q15648,P40763,Q8IYB5,Q99873,P78527 5 +Regulation of cell morphogenesis involved in differentiation 0.2832757012868301 0.0387665134121766 0.9690765431807082 1.0 1.0 28 Q14999,Q14185,P50570,P46109,P60953,P43034,Q9UQB8,Q9P258,P78527,Q14155,Q13418 11 +Negative regulation of cell cell adhesion 0.2696006356214019 0.0387314721403996 0.9691044810884066 1.0 1.0 22 Q9HCM4,P09429,P42574,P51452,Q92990 5 +Positive regulation of epithelial cell migration 0.2905504088265663 0.0387064907603376 0.9691243984106466 1.0 1.0 32 Q9HCM4,P09429,Q14185,O75116,O00443,Q7Z460 6 +Cell aging 0.2946826557091437 0.0383844110809051 0.9693811899779654 1.0 1.0 35 O96017,P67809,P42771,Q13535,Q13315,Q00534 6 +Tumor necrosis factor mediated signaling pathway 0.258281964206626 0.0383617981599119 0.9693992191996416 1.0 1.0 18 P63241,P49327,Q96BN8,Q14790,O15111,Q13418 6 +Regulation of histone h3 k4 methylation 0.2550950487030081 0.0381734316971537 0.9695494038855546 1.0 1.0 17 Q6W2J9,Q9H3P2,P26358,P18615 4 +Regulation of cyclase activity 0.2218246958588114 0.0380069933710536 0.969682106154705 1.0 1.0 7 P21359 1 +Chromosome condensation 0.2753546059472956 0.0377988541055189 0.9698480580122052 1.0 1.0 25 Q15003,Q15021,P16402,Q9BPX3,Q7Z5K2,Q9NTJ3,P53350,Q6IBW4,P42695 9 +Endothelial cell development 0.2654111814212357 0.0376989397345893 0.9699277213666018 1.0 1.0 21 Q13464,O75116,P35241,P55196,P49327,Q9Y696 6 +Negative regulation of actin filament polymerization 0.2599201284145002 0.0376323467816428 0.9699808171787124 1.0 1.0 19 P47756,P35080,P35241,Q9NUQ9,P58546,Q13045,Q6IBS0,P07737,P47755,O15020,Q9BPX3 11 +Positive regulation of protein containing complex assembly 0.3018037366589289 0.0375765165704994 0.9700253317571916 1.0 1.0 57 Q86VP6,Q16512,Q14008,P49841,Q04637,P42345,Q9Y295,Q99996,Q7Z460,Q9Y2A7,Q13535,Q13315,P46821,Q9UQB8,Q9BPX3,Q8WUW1 16 +Cell cycle g2 m phase transition 0.3027801647817933 0.0374103663191329 0.970157807330338 1.0 1.0 55 P23921,Q92547,Q5TBB1,P54132,Q9P258,O14965,Q15058,Q68E01,Q13309,P20248,Q13564,Q99741,P30307,Q96QE3,P50570,P14635,Q13315,P11802,O60921,O96017,O95067,Q96GX5,P53350,Q99640 24 +Negative regulation of leukocyte cell cell adhesion 0.2475842408672128 0.0372581793025392 0.9702791504047444 1.0 1.0 15 P42574,P51452,P09429 3 +Dna strand elongation 0.2592323745755118 0.0372119019612341 0.9703160487931624 1.0 1.0 19 Q07864,P49005 2 +Molting cycle 0.2443550983976088 0.0371948349283085 0.97032965689455 1.0 1.0 14 Q5C9Z4,P18074,P21359 3 +Ncrna transcription 0.2807461738604298 0.0371143115261639 0.9703938609429552 1.0 1.0 28 P42345,O75607,Q12789,Q4G0J3,Q8WUA4,Q7L2J0 6 +Actin filament polymerization 0.2995828541957968 0.037059052266767 0.9704379211417596 1.0 1.0 41 P31146,P42345,Q9UQB8,P35241,O60610,Q13045,Q9Y2A7,P47755,P57737,Q96F07,Q7L576,Q9BPX3,O00401 13 +Canonical wnt signaling pathway 0.298108177399018 0.0366696393487871 0.9707484166445493 1.0 1.0 40 Q70CQ2,Q9HCK8 2 +Response to increased oxygen levels 0.2267339921220054 0.0366690192090676 0.970748911111905 1.0 1.0 9 O95352 1 +Positive regulation of autophagy 0.2940748484846566 0.036184550852139 0.9711352045568372 1.0 1.0 37 P09429,O00443,P42858,Q6PKG0,Q15042,Q9P0V3,Q9Y3I1 7 +Positive regulation of innate immune response 0.2845297975051942 0.0358971802000003 0.9713643442944389 1.0 1.0 31 Q16512,P09429,P55212,Q9NW08,Q9BUI4,P78527 6 +Spindle organization 0.2373322329259015 0.0356139510308781 0.9715901840651356 1.0 1.0 86 Q15398,O43670,Q9BV86,O14965,Q14204,Q9UH99,Q15257,Q8WUX9,Q00610,Q96CW5,P14635,Q9BT25,O96017,Q14008,O95067,P35579,Q14674,Q7Z460,P53350 19 +Regulation of heart growth 0.2281096455141028 0.0354821319801893 0.9716952940176464 1.0 1.0 10 Q92908,P11413,Q99956,Q9UGN5,Q16539 5 +Regulation of cytokinesis 0.2758721097827157 0.035402002119189 0.9717591882539192 1.0 1.0 27 Q9H8V3,O14965,Q15058,P60953,Q13526,Q96Q89,Q16513,Q99570,P61586,P53350,Q13618,Q9NR09 12 +Regulation of double strand break repair 0.2948122305407873 0.0351540084595265 0.971956935475409 1.0 1.0 39 Q96L91,Q7Z4V5,O95071,Q9UBB9,Q9Y4A5 5 +Myotube differentiation 0.2468797034341994 0.0351007383092848 0.971999412690742 1.0 1.0 16 P35579,Q9H4M9,P17655,P42345 4 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.2272415446407729 0.0350115291887408 0.9720705475472824 1.0 1.0 10 P50570,P62942,Q13526 3 +Negative regulation of supramolecular fiber organization 0.2998081003787627 0.0347206311847691 0.972302509538196 1.0 1.0 47 P04350,P63167,Q8WWK9,P31146,P29372,P35241,Q9P1Y5,Q92974,O15344,Q13045,Q7Z460,P47755,Q9UHB6,P46821,Q9BTW9,Q9BPX3,Q14155 17 +Cellular response to radiation 0.2997447721480565 0.0346770706901887 0.9723372448671384 1.0 1.0 47 O60921,P49917,O96017,P09874,P50570,P30419,P31751,Q96RU2,Q13535,P28340,Q13315 11 +Multivesicular body organization 0.2261497918310551 0.0344335465836593 0.9725314330197647 1.0 1.0 10 Q8WUX9 1 +Sister chromatid cohesion 0.2741978270240254 0.0344293443609836 0.972534783921482 1.0 1.0 27 Q9NTI5,Q29RF7,Q14674,Q9BTE3,Q7Z5K2 5 +Positive regulation of dna biosynthetic process 0.283440131231394 0.0341842836968194 0.9727301990099206 1.0 1.0 32 Q13535,Q13315,Q96HR8 3 +Receptor metabolic process 0.2849811396145096 0.0341058242873138 0.9727927640789376 1.0 1.0 33 P50570,Q9Y6D5,Q13614,P49407,Q00610,Q00535,Q99570,Q15334,Q9UL63 9 +Negative regulation of cell adhesion 0.2907353448455593 0.0340711671849063 0.9728204003841574 1.0 1.0 37 Q9HCM4,P09429,Q9BTW9,P42574,P51452,P42771,P21359,Q9P258 8 +Attachment of spindle microtubules to kinetochore 0.2561804124472048 0.0339090327158827 0.9729496902660092 1.0 1.0 20 Q9H8V3,O43670,P60953,Q8IXJ6,P14635,Q9P258 6 +Regulation of gene silencing by rna 0.2585846831230111 0.033758684223451 0.9730695823650652 1.0 1.0 21 P36507,Q06787,Q9HAV4,Q04637,P26196,Q08209,P40763 7 +Histone phosphorylation 0.2684379765985519 0.0337098099503517 0.9731085562105706 1.0 1.0 25 Q16512,O14965,P20248,Q99986,Q00535,Q13315 6 +Selective autophagy 0.2750097758811651 0.0336992368864997 0.9731169875046646 1.0 1.0 28 Q7Z6Z7,Q9Y4P1,P50851,P42858,Q13501 5 +Protein hexamerization 0.2139868499701102 0.0336879969620444 0.9731259505776996 1.0 1.0 7 Q8IWT6,P31153,O60701,Q96TA2,Q96RR1,O95202 6 +Regulation of telomere maintenance 0.2944268183607788 0.0336500117286425 0.973156241235328 1.0 1.0 41 P28482,Q8IZH2,Q13535,Q13315,Q96HR8 5 +Cellular response to reactive oxygen species 0.2800483888121709 0.0332549958591437 0.9734712419935564 1.0 1.0 31 P00374 1 +Cell maturation 0.2650238403514978 0.0331479324458604 0.973556619167812 1.0 1.0 24 O14965,Q5TAX3,Q8NHU6,Q8IXJ6,P18074,P04818 6 +Cellular response to peptide 0.2831562113350693 0.0329720049038962 0.9736969123487073 1.0 1.0 68 P07741,P49841,P09874,P43490,O75116,P31751,Q00535,Q8TBX8,Q7L576,P07814,P20248,P40763,P78527,O14654,Q06124,O00443,P11802,Q9UQB8,P27695,Q13464,Q92974,P46821,Q9Y5X3 23 +Cell junction assembly 0.2683735587262508 0.0327819479701825 0.9738484739083146 1.0 1.0 75 O75116,P46109,Q00535,Q9P258,Q9HCM4,Q8NI35,Q9UPN3,P17612,P51452,P61586,Q9H2G2,Q9H8V3,P55196,Q9P1Y5,Q8TEW0,Q16513,Q14155,P63167,Q13464,Q04637,P60953,Q7Z460,P46821,Q9BTW9 24 +Morphogenesis of an epithelium 0.2841383653562995 0.0323932477667714 0.974158447165455 1.0 1.0 67 Q15648,P62136,Q92990,P07737,Q9Y5V3,Q9HCM4,P17612,P25440,P62081,P20248,P61586,P67870,Q92796,P42345,P42574,Q9P1Y5,Q9Y696,Q96Q89,Q9ULT8,Q13418,P43034,Q16512,P63167,P60953,Q7Z460 25 +Vesicle mediated transport in synapse 0.2845934848108231 0.0321099361316819 0.974384379610141 1.0 1.0 35 P49841,O14617,Q06787,Q13464,Q9Y263,O00203,P50570,Q15042,Q00535,Q4J6C6,O14976,Q7L576 12 +Extrinsic apoptotic signaling pathway via death domain receptors 0.2439228444442452 0.0320376850374832 0.9744419979982046 1.0 1.0 17 Q9UER7,Q9UKL3,Q92974,P21359 4 +Positive regulation of protein serine threonine kinase activity 0.2809227038203417 0.0318276389767938 0.9746095050819436 1.0 1.0 33 Q16512,P14174,P46940,O75909,P14635,Q9Y5V3,O75832 7 +Regulation of growth 0.1623487069230466 0.0317020285049704 0.9747096771882096 1.0 1.0 135 O14681,P49841,P68400,Q9Y263,P46109,Q7Z4V5,P51532,P42771,Q00535,Q7L576,Q9P2D1,Q9HCL2,Q9ULC4,Q15058,Q9UPN3,Q99956,P40763,Q14353,Q92908,P42345,P50570,Q15418,P11802,O60271,Q9P0V3,O75832,O95067,Q04637,Q6PJG6,P60953,Q9P265,P46821,Q99816 33 +Regulation of cellular component size 0.2443696065919253 0.0315541862550458 0.974827579251093 1.0 1.0 83 P49841,P31146,P62136,Q00535,Q9Y2A7,Q9P2J5,Q7L576,Q9Y666,Q9UPN3,P35241,Q13045,P61586,Q96F07,Q9BXP2,Q8WUW1,P42345,P50570,P47755,Q9UQB8,Q9BPX3,Q9P265,Q9UHB6,P46821 23 +Mitotic sister chromatid segregation 0.2303154561495023 0.0313671728103305 0.9749767205646864 1.0 1.0 87 Q15398,O43670,Q6IBW4,Q9GZZ1,Q99661,P42695,Q15058,Q15021,P50748,Q99741,Q969U7,Q9UJX5,Q29RF7,Q8WUX9,P14635,Q5JVF3,Q9NTJ3,Q13315,Q9BPX3,Q15003,Q9BW19,Q9NTI5,Q14674,Q9H900,P53350,Q13618 26 +Regulation of spindle organization 0.2536917382567809 0.0312998169060832 0.9750304364254898 1.0 1.0 21 Q8WUX9,Q00610,Q9Y295,Q14204,P53350 5 +Ribosomal large subunit biogenesis 0.2913175169295951 0.0312279737474813 0.9750877309649482 1.0 1.0 60 P50914,P18124,Q7Z4Q2,P83731,P42766,Q02878,Q9NUL7,P62906,P62424,P39023,Q8IY81,P46777,Q9BYG3,P61254,P27635,Q9NVU7,P62750 17 +Actin polymerization or depolymerization 0.2946976980186586 0.0312035645984642 0.975107197161613 1.0 1.0 48 P31146,P42345,Q9UQB8,P35241,O60610,Q13045,Q9Y2A7,P47755,P57737,Q9UHB6,Q96F07,Q7L576,Q9BPX3,Q8WUW1,O00401 15 +Regulation of epithelial cell migration 0.2910658832484071 0.0306608963003612 0.9755399767211016 1.0 1.0 43 Q9HCM4,P09429,P42345,Q14185,O75116,P42785,O00443,P21359,Q7Z460,P67870 10 +Regulation of t cell activation 0.2865465311204135 0.0303120098775226 0.9758182184776404 1.0 1.0 39 Q06124,P09429,O14617,P42574,P51452,O43290,Q9UDY8,Q9HCL2 8 +Transition metal ion homeostasis 0.2592640064876073 0.0303073292031949 0.9758219514003534 1.0 1.0 24 O60826,O14617 2 +Cellular response to uv 0.2590767398141229 0.0302215571979963 0.9758903562246166 1.0 1.0 24 P09874,P61254,Q96RU2,Q13535,P28340 5 +Negative regulation of cell differentiation 0.2522225350910239 0.0300886074022855 0.9759963865946926 1.0 1.0 80 Q15648,P67809,P21359,Q00535,P26358,Q9P258,P26196,P40763,Q9NYV4,Q9UBS4,Q00534,Q99873,Q9Y3I1,Q06124,Q8IXJ6,O60271,P09429,P28482,Q9P265 19 +Response to reactive oxygen species 0.2822154952383308 0.0300813307730338 0.9760021898779414 1.0 1.0 36 P00374,P27695,O15111,P42574 4 +Erythrocyte homeostasis 0.2821189593555415 0.0300324675149131 0.9760411595102884 1.0 1.0 36 P08708,P62847,P62753,Q00534,P78527 5 +Positive regulation of dna recombination 0.2678063711837247 0.0300157385810923 0.9760545012535116 1.0 1.0 28 P09874,Q96L91,Q7Z4V5,Q96FZ2,Q9Y4A5,P18074 6 +Muscle hypertrophy 0.2452548713562055 0.0299848121469375 0.9760791658760616 1.0 1.0 19 Q92908,O75116,P09874 3 +Dna integrity checkpoint signaling 0.2877525823216385 0.0298179200924372 0.9762122669539276 1.0 1.0 41 Q06124,O60921,O96017,Q92547,Q5TBB1,P61254,Q99459,P54132,Q96RU2,Q13535,Q13315,P53350,Q13564,P78527 14 +Spinal cord development 0.2227504491013441 0.029702000615095 0.976304716366924 1.0 1.0 12 P21359 1 +Regulation of ubiquitin dependent protein catabolic process 0.2860573922026562 0.0288989994307618 0.976945143628416 1.0 1.0 62 P78559,O14965,O14980,P49841,P68400,O60826,O75925,P62081,Q92990,Q8IXJ6,P19784,P46777,P53350,Q9ULT8,O75832 15 +Regulation of response to dna damage stimulus 0.2382760828786434 0.028569301890662 0.9772080956284506 1.0 1.0 84 O96017,P09429,Q06787,Q96QE3,P09874,Q99504,P14174,Q7Z4V5,Q96L91,P61254,O95071,Q13535,Q9UBB9,Q13315,Q96FW1,Q9Y4A5,P78527,O75832 18 +Epithelial tube morphogenesis 0.2835562989542577 0.028229242028977 0.9774793147468376 1.0 1.0 40 Q16512,Q15648,P63167,P17612,P25440,P62081,P42574,P62136,Q92990,Q96Q89,P61586,Q9ULT8,P67870,Q9Y5V3,Q13418 15 +Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.2636385444983904 0.0281657286277389 0.9775299709667437 1.0 1.0 28 Q2NL82,Q8IY37,O75818,P78316,P18074 5 +Positive regulation of membrane potential 0.1970917710316906 0.0281363928349332 0.9775533682700908 1.0 1.0 6 P35754,P31751 2 +Dendrite morphogenesis 0.2676313632484083 0.0280903304610304 0.9775901062060716 1.0 1.0 30 P00492,P49841,Q14999,P61160,Q05086,P60953,Q08209,Q9H2U1,Q00535,O60678,Q9UQB8,Q15334,O00401,P43034 14 +Mrna transcription 0.2106754005789728 0.0277581099870437 0.9778550764648096 1.0 1.0 10 O00203,Q15648,P40763,Q12800 4 +Negative regulation of protein polymerization 0.2575571453920487 0.0275286736298641 0.978038070260125 1.0 1.0 26 P04350,P35241,Q13045,P47755,Q9BTW9,Q9BPX3 6 +Protein containing complex disassembly 0.2116578196208757 0.0275037608832135 0.9780579402324228 1.0 1.0 91 P49841,P62136,P51532,Q99661,P35241,Q13045,Q9UBB9,Q08945,Q9H269,P17096,Q9P1Y5,Q8WUX9,P47755,O14976,Q9BPX3,P46821,Q14562,P78559,Q14008,P29372,Q92974,P63241,Q7Z460,Q99570,Q9UHB6,Q9Y5B9,Q66K74,Q99816 28 +Positive regulation of interleukin 2 production 0.2062805931632676 0.0274785883048755 0.978078017455772 1.0 1.0 9 Q9UDY8 1 +Homeostasis of number of cells 0.2838249582090856 0.0274447155132555 0.9781050338442135 1.0 1.0 62 Q06124,Q16512,Q15648,P08708,P09429,O95067,P62847,P14174,P18074,O00203,P42574,P49327,P40763,P62753,Q00534,Q15020,Q9HCL2,P78527 18 +Positive regulation of telomerase activity 0.2265177486230929 0.027392288629483 0.9781468487247122 1.0 1.0 15 Q96HR8 1 +Regulation of tumor necrosis factor mediated signaling pathway 0.2020952696459193 0.0272997042461465 0.9782206927591446 1.0 1.0 8 Q96BN8,Q14790 2 +Protein containing complex localization 0.2869649364503031 0.0271530666837988 0.978337649249513 1.0 1.0 47 O14617,P62841,Q9NVU7,Q15334,Q13535,Q13315,Q9P258,Q96D46 8 +Response to alkaloid 0.2516008163961701 0.0271118952314081 0.9783704872263026 1.0 1.0 24 P55212,P42574,P50570,Q00535,P63151 5 +Microtubule organizing center organization 0.2837698342227858 0.0269231284198776 0.9785210463905368 1.0 1.0 43 O14965,O14980,Q8NI35,Q14008,O75116,Q9Y496,Q7Z460,Q12873,P53350,Q9BT25 10 +Negative regulation of protein containing complex assembly 0.2817994135587455 0.0269025463335968 0.9785374625732052 1.0 1.0 41 P04350,P09429,P49841,Q15058,P60953,P35241,Q13045,P40429,Q8IXJ6,Q9UBB9,P47755,Q9BTW9,Q9BPX3,Q14155 14 +Signal transduction in response to dna damage 0.2875272362346877 0.0268285976219246 0.9785964438195636 1.0 1.0 51 Q9UM54,Q06124,O60921,O96017,Q96QE3,P14174,Q92547,P61254,Q96RU2,Q13535,Q13315,P53350,P78527,O75832 14 +Rna phosphodiester bond hydrolysis 0.2749843224023763 0.0267044267795368 0.9786954823333056 1.0 1.0 68 Q2NL82,Q9UIV1,P27695,Q8IZH2,A5YKK6,O75818,P78316,Q99575,O15091,Q9Y2L1,Q9H9L3,Q96C86,Q96DE0 13 +Regulation of carbohydrate biosynthetic process 0.2333092956331862 0.0265166979908484 0.9788452152112376 1.0 1.0 18 P31751,P49841,Q00610,P62136 4 +Dna biosynthetic process 0.2587913607569242 0.0265125002968749 0.9788485633093464 1.0 1.0 76 Q07864,P28482,Q8IZH2,P04183,P18858,P35251,Q13535,P28340,Q13315,Q96HR8,P49005 11 +Regulation of establishment of protein localization to mitochondrion 0.2389277600713334 0.0264301405968438 0.9789142538226994 1.0 1.0 20 P19784,Q96EP0,Q7Z6Z7 3 +Synapse assembly 0.2298770881154574 0.0263887821296148 0.97894724159933 1.0 1.0 17 P46109,Q00535,Q04637,P46821 4 +Regulation of dendrite morphogenesis 0.2230861418874297 0.0262386854121094 0.9790669599983036 1.0 1.0 15 P49841,Q14999,P61160,Q08209,Q9H2U1,Q9UQB8,P43034 7 +Positive regulation of protein localization to nucleus 0.2779499578263649 0.0262301195444684 0.9790737922203224 1.0 1.0 39 P09874,O95071,Q4G0J3,P53350,Q7L2J0,Q96D46 6 +Modulation by host of symbiont process 0.2353792097562341 0.0262118021883872 0.9790884023325612 1.0 1.0 19 Q9H6S0,O75909,O14646,P51532 4 +Regulation of cell activation 0.2720054357558284 0.0257948144010789 0.9794209979827386 1.0 1.0 69 Q06124,Q16512,P09429,O14617,P14174,P51452,O00203,P42574,O43290,Q92614,Q5JVF3,Q13315,Q9UDY8,Q96FZ2,Q9HCL2,P78527,Q9Y3I1 17 +Epithelial cell development 0.2791006427071951 0.0257238358508006 0.979477611886151 1.0 1.0 41 Q9HCM4,P49841,Q13464,O75116,P55196,P49327,P46940,Q00534,P04818 9 +Positive regulation of chromosome organization 0.2847420963233373 0.0256782382972267 0.979513981456333 1.0 1.0 49 Q15021,P28482,Q13535,Q9NTJ3,P26358,Q13315,Q9BPX3,Q96HR8 8 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.1954441696540201 0.0253096790277907 0.9798079536575396 1.0 1.0 8 Q96BN8 1 +Organelle disassembly 0.2844426591694569 0.0252480085253893 0.979857143879977 1.0 1.0 52 Q9ULC4,Q9NT62,Q7Z6Z7,Q9Y4P1,P50851,P42858,Q99986,P19784,Q92538,Q13501,Q9Y3I1 11 +Myeloid leukocyte differentiation 0.2642492557255546 0.0252217879875052 0.9798780581821552 1.0 1.0 32 Q15648,P09874,P42345,O00203,P35579,P60953,P21359,P49327,Q00534 9 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.2211995026276187 0.0247056824053984 0.9802897225611424 1.0 1.0 16 Q92908,P67870,P20248,P09874 4 +Cell cell junction assembly 0.2674360087194171 0.0244335578092935 0.9805067810489916 1.0 1.0 35 Q8NI35,Q13464,P17612,O75116,P55196,Q8TEW0,Q16513,Q9BTW9 8 +Positive regulation of secretion 0.2815076122188184 0.0244093376368248 0.9805261001887686 1.0 1.0 48 Q06124,P35580,P14174,Q92614,O00429,Q15042,P22059,Q00535,Q7Z460,O95486,P08237,Q9Y5K6,Q99816 13 +Substantia nigra development 0.2159820532718483 0.0241824918525291 0.9807070435248176 1.0 1.0 15 P63167,P60953,P12277,Q8IXJ6,P61586 5 +Vesicle organization 0.2123253493764962 0.0239621174104173 0.980882825951204 1.0 1.0 90 Q7Z3T8,Q15436,Q99816,P31751,Q13190,Q9P2R3,O75165,Q9Y6D5,Q9Y5K6,P22059,Q9BXS5,Q9Y6B6,O00203,Q8WUX9,Q92614,O95486,Q13501,O14617,P40818,Q92538,Q2M389,Q15334,O00401,Q13618,O00743 25 +Isoprenoid biosynthetic process 0.197232322179776 0.0238917230511258 0.980938976448328 1.0 1.0 10 P04035 1 +Response to dopamine 0.217863521146946 0.0238183248540497 0.9809975230758472 1.0 1.0 16 P50570,P49841,O14744,P28482 4 +Positive regulation of establishment of protein localization 0.1732998812488077 0.0236731726412914 0.9811133051381992 1.0 1.0 99 Q96EP0,P49841,P30419,P31751,O95071,Q00535,Q9Y5K6,P17612,P22059,Q9Y6B6,Q9H8V3,Q7Z6Z7,Q92614,O00429,Q96Q89,P19784,O95486,P35580,P60953,P08237,Q99816 21 +Multicellular organism growth 0.2595609329463214 0.0236371659886827 0.9811420262535816 1.0 1.0 32 Q06124,P42345,Q9BZH6,P40763,Q13315,P11802,Q9P2D1,Q9HCL2,P18074,Q14353 10 +Response to peptide 0.199894903758385 0.0234505421308701 0.9812908892841125 1.0 1.0 93 P49841,P07741,O15357,P43490,O75116,P09874,P31751,Q00535,Q8TBX8,Q13144,P07814,P20248,P49770,P40763,P78527,O14654,Q06124,P42345,O00443,P11802,Q9UQB8,P27695,Q13464,Q92974,P46821,Q9Y5X3 26 +Nucleotide phosphorylation 0.2636225447318453 0.0231555553186867 0.9815261908095284 1.0 1.0 35 P22392,P04075,P14618,P15531,Q9BRR6,Q01813,P09972,P40763,P17858,P85037,P08237,P06744,P18669 13 +Epidermis development 0.279554598486609 0.0230179010541614 0.9816359937556144 1.0 1.0 53 Q9UM54,Q92908,Q15648,P22392,P67809,O00203,O75116,P42574,P21359,P29375,P18074,Q99816 12 +Hematopoietic progenitor cell differentiation 0.250953036031401 0.0229726725778271 0.981672071318721 1.0 1.0 29 P49917,Q00534,Q9Y520,P18074,P78527 5 +Regulation of actin filament length 0.2729435867438914 0.022936564453284 0.9817008738445778 1.0 1.0 42 P31146,P42345,Q9UQB8,P35241,Q13045,Q9Y2A7,P47755,Q9UHB6,Q96F07,Q7L576,Q9BPX3,Q8WUW1 12 +Programmed cell death 0.1682059117857207 0.0229361367266633 0.9817012150312878 1.0 1.0 443 Q15648,Q14185,Q00535,P26358,P78362,Q9NRZ9,P42858,P08243,P20248,Q13564,Q92908,Q969U7,Q96QE3,P62753,Q53T59,Q9NR09,Q9HCK8,O75832,P47897,Q05639,P27695,Q13464,Q5VZE5,P60953,Q14674,Q92974,Q9NP92,O75569,P17655,P49841,P68400,Q99504,Q92905,P42771,Q969G6,Q9UPY5,P15531,Q99956,P27635,P78527,Q9NT62,Q9H2G2,Q9H8V3,P55212,P42574,Q9UDX5,Q15418,O00429,Q8IXJ6,P19784,Q13315,Q9UDY8,P31689,P33993,Q14155,O96017,P63167,P51858,Q96C86,O95881,O14681,P21359,Q9Y2A7,Q9HCL2,Q9UKL3,P52701,P49427,P62081,Q13309,P18074,P61247,Q15257,Q92614,Q96RU2,Q13501,O60333,P09429,P28482,P61803,P53350,Q66K74,Q13616,P09874,O95352,P30419,P31751,P49327,Q13144,Q9UER7,Q9Y5V3,O14965,P06737,P14174,Q96F07,Q9Y6C9,P49917,P42345,P50570,Q16513,Q5JVF3,Q16512,P22392,P22681,P61254,P61289,P63241 106 +Nadh metabolic process 0.223464627956424 0.0228477115720771 0.9817717496129964 1.0 1.0 19 P85037,P17858 2 +Developmental maturation 0.2726657163240096 0.0228399888865359 0.981777909817023 1.0 1.0 42 O14965,O14617,Q5TAX3,Q15058,P17612,Q9BXS5,Q8NHU6,P21359,Q8IXJ6,Q5C9Z4,P61586,P46821,Q15334,P18074,P04818 15 +Heterochromatin organization 0.2545184910578701 0.0227370597454315 0.9818600140677024 1.0 1.0 31 Q9NRZ9,Q9UPP1,Q8IXJ6,Q9UIF9,P26358 5 +Interleukin 2 production 0.1912679222458178 0.022630713256023 0.9819448444617404 1.0 1.0 10 Q9UDY8 1 +Myeloid cell homeostasis 0.2704871097131086 0.0224979412173454 0.982050754256072 1.0 1.0 41 Q15648,P08708,P09429,P62847,P42574,P40763,P62753,Q00534,P18074,P78527 10 +Activation of innate immune response 0.2302954603357133 0.0223325136874177 0.9821827131729391 1.0 1.0 22 P09429,P78527,P55212 3 +Muscle cell proliferation 0.2433639260274223 0.0222212252104667 0.9822714865004374 1.0 1.0 27 Q5VZE5,P26358 2 +Positive regulation of viral process 0.2496976756227751 0.0220189748373286 0.98243281947546 1.0 1.0 30 P78362,Q9UIV1,Q6PKG0,Q96SB4,Q99816 5 +Endothelium development 0.2399711588283185 0.0220136908463897 0.9824370344685822 1.0 1.0 26 Q13464,O75116,P35241,P55196,P49327,Q9Y696,P61586,P67870 8 +Positive regulation of exocytosis 0.206026266953852 0.0219555368648658 0.9824834234207986 1.0 1.0 15 Q7Z460,Q99816 2 +Keratinocyte differentiation 0.2370469622992584 0.021947514673907 0.9824898226611234 1.0 1.0 25 P22392,Q15648,P42574,O75116,Q99816 5 +Cell cell junction organization 0.2743623673313012 0.021868212181729 0.9825530817126946 1.0 1.0 47 Q8NI35,Q13464,P17612,O75116,P35241,P55196,Q9P1Y5,P60953,Q8TEW0,Q16513,Q9BTW9 11 +Chromatin remodeling 0.206212030933505 0.0217792716970481 0.9826240290549686 1.0 1.0 91 O75607,P51532,Q12873,Q9P2D1,Q9UER7,Q9NRZ9,P25440,Q14839,Q14997,P29375,P17096,Q9H4L7,Q15020,Q9HCK8,Q16512,O14646,Q9Y6J9,Q86WJ1,Q9UKK9 19 +Positive regulation of cytokine production 0.2651776776963894 0.021743563177375 0.9826525135861476 1.0 1.0 69 Q92908,Q06124,O15111,P09429,Q9UDY8,P30046,P14174,O75116,Q9NW08,Q92974,P40763,Q96RD7,O14802,Q9BUI4,Q9Y6D5,Q92499 16 +Epidermal cell differentiation 0.2621678340884035 0.021700941629572 0.9826865126388156 1.0 1.0 37 Q9UM54,Q92908,Q15648,P22392,P42574,O75116,P18074,Q99816 8 +Myeloid leukocyte migration 0.2380341339087002 0.0215614024748322 0.9827978227314538 1.0 1.0 26 P09429,Q92538,P28482,P30046 4 +Cellular response to abiotic stimulus 0.2559350689122258 0.0215450014200155 0.9828109058407026 1.0 1.0 74 O60921,P49917,O96017,P09874,P42574,P50570,P30419,P31751,P49327,Q96RU2,Q13535,P28340,Q13315,Q9UKL3 14 +Regulation of t cell proliferation 0.2196022760998348 0.0213542269783396 0.9829630868098912 1.0 1.0 20 P42574,Q9HCL2 2 +Cytokine mediated signaling pathway 0.2752592112789441 0.0213127428153301 0.98299617885183 1.0 1.0 53 Q06124,Q15648,Q9UIV1,P17612,P22681,Q01804,P63241,P49327,Q96BN8,P40763,Q14166,P43034,Q14790,P67870,Q9Y3Z3,Q92600,O15111,Q13418 18 +Positive regulation of response to biotic stimulus 0.2570892951211659 0.0212683249296192 0.9830316111656484 1.0 1.0 35 Q16512,P09429,P55212,P14174,Q9NW08,Q9BUI4,P78527 7 +Regulation of cell morphogenesis 0.2553395734133039 0.0212010640172485 0.9830852655111 1.0 1.0 74 P31146,Q9Y263,Q14185,P46109,Q7L576,Q9P258,Q9UL63,Q14999,Q9UPN3,P35241,O60610,Q6XZF7,Q5VZL5,P78527,Q9HCE1,P50570,Q7KZI7,O60271,Q9UQB8,Q14155,Q13418,P63167,P35580,P35579,P60953,Q15334 26 +Negative regulation of ubiquitin dependent protein catabolic process 0.2363179073896792 0.021182699941359 0.983099914633926 1.0 1.0 26 P62081,P78559,P19784,P46777 4 +Neuron projection guidance 0.2331330795702557 0.0210854814917096 0.9831774664127187 1.0 1.0 25 O75592,Q9BPU6 2 +Histone h3 k4 methylation 0.2330048277564376 0.021058986094022 0.9831986019884342 1.0 1.0 25 P18615,P16402,Q86TU7,P26358,Q9H3P2,Q6W2J9,Q6UXN9 7 +Negative regulation of cell development 0.2328380421068751 0.0210246910096318 0.983225959449728 1.0 1.0 25 P49841,Q08209,P21359,Q8IXJ6,Q00535,Q9P265,Q9UBS4,Q9P258 8 +Glycerolipid biosynthetic process 0.2730439998401951 0.0210007470184005 0.983245059773465 1.0 1.0 49 O96017,P35790,O00443,P42356,Q01968,Q08AM6,Q13315,Q8NCE2 8 +Negative regulation of dna recombination 0.2066813960095315 0.0208408359388627 0.9833726224359568 1.0 1.0 17 P52701,Q15554,Q92522,P16402,P20585,P54132 6 +Tissue migration 0.2730391766742936 0.0205613158349879 0.983595599428756 1.0 1.0 57 Q06124,Q9HCM4,P09429,Q16512,P42345,Q14185,O75116,P35579,O00443,P21359,Q16513,Q7Z460,P67870 13 +Cellular response to insulin stimulus 0.2707488709908214 0.0204547948643393 0.9836805729956136 1.0 1.0 48 Q06124,P07741,P49841,P09874,P43490,P07814,O00443,P31751,Q9Y5X3,Q8TBX8,P11802,Q9UQB8,P78527,O14654 14 +Negative regulation of nervous system development 0.2141044353562606 0.0203863408070892 0.9837351800442616 1.0 1.0 20 Q08209,P21359,Q8IXJ6,Q00535,Q9P265,Q9UBS4 6 +Nuclear membrane organization 0.2161281091804648 0.020183945451201 0.9838966349519096 1.0 1.0 21 Q14203,Q8WUX9,Q9H6H4,Q99986,Q8IXJ6,P53350,Q6NUK4 7 +Regulation of peptidyl serine phosphorylation 0.2223065880046016 0.0201560964888047 0.9839188506895682 1.0 1.0 23 P49593,Q14012,Q16512,Q04637,P14174,Q13153,Q96N67,Q99996,Q9UHD2,P63244,Q13043,Q92600 12 +Regulation of cell cell adhesion 0.2719269705436355 0.0201361205726473 0.9839347859305458 1.0 1.0 53 Q06124,Q9HCM4,P09429,O14617,O00203,P51452,P42574,O43290,Q9UDY8,Q9HCL2 10 +Neural nucleus development 0.1997627645445417 0.0198480831469952 0.9841645606213748 1.0 1.0 17 P63167,P60953,P12277,Q8IXJ6,P61586 5 +Response to peptide hormone 0.2278768005872333 0.0198290583310677 0.9841797372414588 1.0 1.0 84 P49841,P07741,O15357,P43490,O75116,P09874,P31751,Q8TBX8,Q13144,P07814,P20248,P49770,P40763,P78527,O14654,Q06124,P42345,O00443,P11802,Q9UQB8,P27695,Q13464,P46821,Q9Y5X3 24 +Animal organ morphogenesis 0.1653561327936077 0.0197539781093583 0.9842396308597288 1.0 1.0 100 Q9UM54,O75569,Q15648,Q13616,O15357,P21359,Q9P2D1,Q9Y5V3,P20248,P40763,Q14353,Q92908,P42345,O00203,Q8NHU6,Q15418,P62942,Q13418,O75592,P63167,P28482,P60953,Q9UID3,Q6W2J9,Q13618 25 +Negative regulation of transporter activity 0.178666950563924 0.0197537654235681 0.9842398005253308 1.0 1.0 12 Q06787,P28161,Q12955,Q9HD26,P62942 5 +Regulation of hemopoiesis 0.2703873695694533 0.019719660371107 0.9842670071206184 1.0 1.0 52 Q15648,P09429,O14617,P42345,O00203,P21359,P40763,Q5JVF3,Q00534,Q9UDY8,O43290,P78527,Q9Y3I1 13 +Cleavage involved in rrna processing 0.2129660140990115 0.0197096418789093 0.98427499916759 1.0 1.0 21 Q2NL82,O75818 2 +Regulation of organ growth 0.1776957176474785 0.0196619084716027 0.9843130775373456 1.0 1.0 12 Q92908,P11413,P06493,Q99956,Q9UGN5,Q16539 6 +Positive regulation of response to cytokine stimulus 0.176593834181385 0.0195619353700511 0.984392829192722 1.0 1.0 12 Q7Z434,Q15648,Q99829,P0DMV9,Q9NZI8,Q12933,P61086,Q08211,Q13546,Q9UHD2,P43034 11 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.1849058349106774 0.0195216711822349 0.9844249492329122 1.0 1.0 14 P50570,Q13526,Q9UPN9,Q9Y3F4,P62942 5 +Negative regulation of gene expression epigenetic 0.2401443538872877 0.0194125954220195 0.9845119626086424 1.0 1.0 31 Q8IXJ6,P26358 2 +Regulation of glucose transmembrane transport 0.1784229992486 0.0193288121006392 0.9845787994866227 1.0 1.0 13 P31751 1 +Gene silencing by rna 0.2671817605181768 0.0192072781808139 0.9846757515260464 1.0 1.0 49 P36507,O75569,Q9UIV1,Q5TAX3,Q9HCE1,Q92600,Q9HAV4,Q8IWR0,Q06787,Q04637,A5YKK6,P26196,P40763,P42694 14 +Mitotic cytokinesis 0.2498702574214739 0.0191661695333805 0.9847085454443724 1.0 1.0 36 Q9H8V3,P35580,Q14999,Q13464,O75116,P40818,Q8WUX9,Q14674,Q96Q89,P61586,P53350 11 +Carbohydrate biosynthetic process 0.26280257964354 0.0189777390524643 0.9848588638748006 1.0 1.0 45 Q9NR45,O43505,P49841,Q00796,P31751,P62136,Q00610,Q15185,Q8NCH0,O95782,P46976,P35573,P06744,P13807 14 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.2295838902120498 0.0189631769882991 0.9848704806304742 1.0 1.0 28 P62829,P78559,Q04323,Q93009,P68400,P62081,O43765,P46379,P19784,P46777,O94966,P62913 12 +Snrna metabolic process 0.2264304261894615 0.0189225150639922 0.9849029183317336 1.0 1.0 27 Q6P9B9,Q86W50,Q7L2J0,Q4G0J3 4 +Positive regulation of macroautophagy 0.2197624583545457 0.0188459657482221 0.9849639849593176 1.0 1.0 25 Q15042,Q6PKG0,P42858 3 +Negative regulation of secretion 0.2023100969894841 0.0188386357812253 0.9849698323887102 1.0 1.0 20 Q06124,Q06787,Q08209,P21359,P04035,P17858 6 +Immune response regulating cell surface receptor signaling pathway 0.2428198230779964 0.0186382700169226 0.9851296730734308 1.0 1.0 34 Q16512,Q96EP0,P28482,P51452,P46109,P19174,P49770,Q13144,Q9UDY8 9 +Cortical cytoskeleton organization 0.227066638391882 0.0185967159327295 0.9851628226901348 1.0 1.0 28 Q9H8V3,Q13464,O75116,Q00535,Q9Y2A7,P61586,Q9Y613,Q15334 8 +Negative regulation of cytoskeleton organization 0.2629591018240994 0.0185215132152434 0.9852228154444692 1.0 1.0 47 P04350,P63167,Q8WWK9,P31146,P29372,P35241,Q9P1Y5,Q92974,O15344,Q13045,Q7Z460,P47755,Q9UHB6,P46821,Q9BTW9,Q9BPX3,Q14155 17 +Regulation of pattern recognition receptor signaling pathway 0.1967574172205452 0.0183131912132291 0.9853890041653488 1.0 1.0 20 Q01804 1 +Carbohydrate transmembrane transport 0.171563235098987 0.0182191139674011 0.9854640544258986 1.0 1.0 15 P31751 1 +Actomyosin structure organization 0.2651280446112017 0.0181970930650576 0.9854816216515764 1.0 1.0 52 Q16512,Q9HCM4,Q9H8V3,P63167,P35580,Q13464,P42345,P35579,O75116,P60953,P49407,Q92614,Q13045,Q7Z460,Q9Y613 15 +Positive regulation of cell growth 0.2503694573771592 0.0181696771800672 0.985503492746951 1.0 1.0 39 Q9UPN3,P68400,Q9Y263,Q6PJG6,Q04637,P60953,Q7Z4V5,Q15418,P61586,P46821,Q7L576,O75832 12 +Regulation of dna replication 0.2600452147523206 0.0180773186703253 0.9855771720745136 1.0 1.0 46 Q96QE3,O43913,Q29RF7,P20248,Q13535,P31949,Q7Z7L1,Q7Z5K2,Q9UBD5 9 +Granulocyte chemotaxis 0.1739866698414006 0.0180610672186598 0.9855901367402612 1.0 1.0 16 Q92538 1 +Defense response to symbiont 0.2620422163739797 0.0178803603285092 0.9857342966978868 1.0 1.0 64 Q9HCE1,Q9UIV1,Q9UII4,Q9NW08,O95352,Q13309,Q7Z7L1,O14802,Q9BUI4,Q9HCL2,Q92499,Q14258 12 +Gastrulation 0.2213418030544419 0.0178753192768775 0.9857383182324267 1.0 1.0 28 Q92908,Q9HCM4,P17612,Q16881,O60701,Q9NPQ8,Q7Z460,P62753 8 +Ameboidal type cell migration 0.2468470923918874 0.017859774069401 0.9857507195337558 1.0 1.0 75 Q14185,O75116,P21359,Q9P258,Q9HCM4,Q9UPN3,Q9NPQ8,P67870,Q06124,P42345,O00443,Q16513,Q16512,P09429,Q13464,P35579,P42785,P46940,Q7Z460 19 +Positive regulation of insulin secretion 0.149859833293539 0.0177436488692351 0.98584335935805 1.0 1.0 14 P08237 1 +Positive regulation of mapk cascade 0.2603058093976369 0.0176885709467917 0.985887298286114 1.0 1.0 48 Q06124,P36507,P09429,Q16512,Q13464,P29372,P30046,P14174,O75116,P60953,P49407,P46940,O60271,Q99873,Q9Y5V3 15 +Positive regulation of hormone secretion 0.1773509314719583 0.0176828150891817 0.9858918900778602 1.0 1.0 18 Q06124,P08237 2 +Nucleoside monophosphate metabolic process 0.2470275091879611 0.0175861529425466 0.9859690033211655 1.0 1.0 39 P00492,P07741,O15067,Q9Y3D8,P31939,P04183,P27708,Q969G6,P11172,P20839,Q9P2T1,P33316,Q01433,P04818,P11908 15 +Response to type i interferon 0.1570223086594321 0.0174841974441744 0.9860503395334836 1.0 1.0 16 Q06124,Q9Y3Z3,Q9UIV1 3 +Positive regulation of peptide secretion 0.1441653948032711 0.0174647616194879 0.986065844710436 1.0 1.0 15 P08237 1 +B cell activation 0.2499058577922199 0.0174579180779416 0.9860713042342136 1.0 1.0 41 Q16512,P49917,P52701,P14174,P42574,P17812,Q5JVF3,Q13315,Q9UDY8,Q96FZ2,P78527 11 +Negative regulation of cell projection organization 0.218982697209295 0.0172875283549779 0.9862072350490312 1.0 1.0 29 P50570,Q08209,P10589,Q00535,P61586,Q9P265,O14976 7 +Purine nucleoside monophosphate metabolic process 0.2058977472503645 0.0171099024092731 0.9863489390892402 1.0 1.0 26 P00492,P31939,P11908,Q9P2T1,Q01433,O15067 6 +Regulation of protein targeting 0.2035667987701343 0.0169491271852685 0.9864772005585528 1.0 1.0 26 P19784,Q96EP0,Q7Z6Z7,P31751 4 +Leukocyte cell cell adhesion 0.2543809814009139 0.0169293247815311 0.9864929983241142 1.0 1.0 46 Q06124,P09429,O14617,P42574,P51452,O43290,Q9UDY8,Q9HCL2 8 +Response to bmp 0.1550349351998291 0.0168740372105405 0.9865371051230318 1.0 1.0 19 Q92908,P98170,Q8N0X7,Q93008,Q53EL6,P20248,Q9UPN9,Q13418 8 +Regulation of embryonic development 0.1303992478131773 0.0168676984144193 0.9865421620308756 1.0 1.0 18 P06493,P46379,Q9H2U1,Q14669,Q7Z460,P63244,P43034 7 +Developmental cell growth 0.2537831545616938 0.0168207099172302 0.9865796481090272 1.0 1.0 46 O14965,Q9BRT6,Q9UPN3,Q9Y263,P50570,Q93008,O60271,P46940,Q00535,Q9P265,P46821,Q96F07 12 +Axon extension 0.201252101649463 0.0168041131222655 0.9865928885641012 1.0 1.0 26 P49841,Q9UPN3,P50570,Q93008,Q00535,Q9P265,P46821,Q7L576 8 +Negative regulation of wnt signaling pathway 0.158935276319482 0.0165627600562804 0.9867854336506048 1.0 1.0 21 Q9HCK8 1 +Regulation of cellular protein catabolic process 0.2067249366195023 0.0165618728223443 0.9867861414637772 1.0 1.0 89 P49841,P68400,Q92990,O14965,O14980,P17612,P62081,P35241,P46777,Q8IXJ6,P19784,Q9ULT8,O75832,P78559,O60826,O75925,Q06787,P61289,P53350 19 +Leukocyte chemotaxis 0.2090138982998541 0.0164860079785019 0.986846664588173 1.0 1.0 29 P09429,Q92538,P28482,P30046 4 +Positive regulation of peptidase activity 0.2451489526023177 0.0164353312492529 0.9868870932905054 1.0 1.0 42 P09429,O75116,P61289,P20248,P49327,Q14997,Q96F07,Q9UDY8,Q9UKL3 9 +Regulation of leukocyte migration 0.1990389097737916 0.0164264830373042 0.9868941521892836 1.0 1.0 27 P09429,P28482,P30046,P14174,P46109,O00429,O00401 7 +Positive regulation of developmental growth 0.1990345806370236 0.0164262669333703 0.986894324592015 1.0 1.0 27 Q9UPN3,Q9Y263,P46821,Q9P2D1,Q9HCL2 5 +Negative regulation of dna binding transcription factor activity 0.214114940473769 0.0162989600999641 0.9869958871519636 1.0 1.0 31 O60826,P49407,O15111,P42771 4 +Neural precursor cell proliferation 0.2129531194229607 0.0162193131610944 0.9870594278154414 1.0 1.0 31 Q9UBD5,Q8IXJ6,P21359 3 +Ribonucleoside monophosphate metabolic process 0.2160608392745344 0.0161724387251369 0.9870968232993258 1.0 1.0 32 P00492,P07741,O15067,P31939,P27708,Q969G6,P11172,Q9P2T1,Q01433,P20839,P11908 11 +Response to toxic substance 0.2542851272538415 0.0161085951075708 0.9871477565011826 1.0 1.0 50 P00374 1 +Vesicle budding from membrane 0.2276204737186141 0.0160427019656106 0.9872003248288432 1.0 1.0 36 O14617,P53992,Q15436,O00203,P55735,O15027,Q8WUX9,Q92614,Q92538,O95486,O00401,Q13618,Q9Y6B6,O00743 14 +Positive regulation of mrna metabolic process 0.2553550606858454 0.0160084183617041 0.9872276756747592 1.0 1.0 65 Q9HCE1,Q5TAX3,Q86TB9,P67809,O75116,Q86W50,Q9Y2L1,Q96C86 8 +Cell activation involved in immune response 0.234053965570685 0.0158754812282362 0.9873337306834608 1.0 1.0 39 P49917,P52701,P09429,P22681,P42345,P40763,Q92538,P62753,Q9UDY8,Q96FZ2 10 +Regulation of axonogenesis 0.1731857973772048 0.0158580543426977 0.987347633576208 1.0 1.0 26 Q16512,P49841,Q9UPN3,Q7KZI7,Q00535,Q9P265,P46821,Q7L576 8 +Muscle organ development 0.2401000858224379 0.0157822880862837 0.9874080787379012 1.0 1.0 42 Q15648,P21359,Q8IXJ6,P85037,Q9P2D1,P62942 6 +Lamellipodium organization 0.1679958222358331 0.0156146537569778 0.9875418151008152 1.0 1.0 27 P42345,P50570,P60953,Q9Y2A7,Q8WUW1,Q14155 6 +Positive regulation of defense response 0.2360137618159267 0.0155758742322837 0.9875727529223846 1.0 1.0 41 Q16512,Q96EP0,P09429,P55212,P30046,Q9NW08,Q9BUI4,P78527 8 +Organic acid biosynthetic process 0.2202961340791808 0.0154566955998163 0.9876678322670442 1.0 1.0 84 P00374,P49903,P14174,O60701,P53396,Q99707,P27708,P08243,O95864,P49327,Q9BZF3,Q13126,O00154,Q14353 14 +Maintenance of protein location 0.1968451294913955 0.0154418990734228 0.987679636778168 1.0 1.0 31 O60826,Q7L5D6,Q9UNN5,Q00535,Q9UH99,Q9HD26,Q5THJ4,O15258,O00221,O75832 10 +Regulation of organelle assembly 0.2541342289310805 0.0153708065316764 0.9877363536881631 1.0 1.0 63 Q9NT62,Q8TC07,P27695,A5YKK6,Q8WUX9,P42858,Q15042,Q14204,P53350,Q9BPX3,Q99816 11 +Maintenance of cell number 0.1961543403475089 0.0152186285008407 0.9878577599883228 1.0 1.0 32 P49917,Q5TAX3,Q9Y6J9,A5YKK6,P26196 5 +Reactive oxygen species metabolic process 0.2410382670781228 0.0151981185023733 0.987874122707028 1.0 1.0 45 P00374,A1X283,Q8IXJ6 3 +Regulation of cell size 0.2366189891924133 0.0151687767752176 0.9878975313196798 1.0 1.0 43 P49841,Q9UPN3,P42345,P50570,P35241,Q00535,P61586,Q9P265,P46821,Q9P2J5,Q7L576,Q9Y666,Q9BXP2 13 +Dna packaging 0.2137037125859327 0.0150677617595588 0.987978120430716 1.0 1.0 86 Q9UPP1,P26358,Q6IBW4,Q9UER7,P42695,Q9NRZ9,Q15021,P25440,Q14997,P16402,Q8IXJ6,O14929,Q9NTJ3,Q15020,Q9BPX3,Q96SB4,P33993,Q15047,Q15003,Q9UIF9,Q7Z5K2,P53350,Q8TEX9 23 +Regulation of dna repair 0.2530942278130945 0.0150652977765018 0.9879800861816296 1.0 1.0 57 P09429,P09874,Q99504,Q7Z4V5,Q96L91,O95071,Q9UBB9,Q9Y4A5,P78527 9 +Positive regulation of translation 0.2528957425413307 0.0149527519987132 0.9880698746061372 1.0 1.0 61 O15371,Q06787,P67809,P42345,Q04637,Q6PKG0,P61254,Q7Z478,P63241,Q13144,P46777,P62701,Q96P11,P78527 14 +Metencephalon development 0.1549468310265319 0.0148835255600792 0.9881251031667876 1.0 1.0 31 Q06124,P27695,P31939,P12277,P46109,Q00535 6 +Positive regulation of nf kappab transcription factor activity 0.1695257122319425 0.0147924493765802 0.988197763448336 1.0 1.0 32 Q96EP0,P40763,Q9UDY8,O15111,Q14258 5 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.2313362452461627 0.0146915593850774 0.9882782532680928 1.0 1.0 43 O75925,O14965,P49841,O60826,Q06787,Q8IXJ6,P53350,Q9ULT8,O75832 9 +Response to monosaccharide 0.1963349268297793 0.0146493731647365 0.9883119093800066 1.0 1.0 35 P17612,P42574,Q08209,P51532,P22059,P49770,Q13144,P17858,Q9HCL2 9 +Cellular response to inorganic substance 0.2241504756499395 0.0145979288005494 0.9883529516552234 1.0 1.0 41 P49917,Q06787,P28482,P09874,P50570,Q9BY42,Q99707,P20248,P46940,Q15334,Q9UER7,O15111 12 +Blastocyst development 0.1830145324438009 0.0144185399313198 0.9884960682011574 1.0 1.0 35 P61803,A5YKK6,P26373,Q8IWS0 4 +Peptidyl proline modification 0.2002943699592153 0.0143782619348201 0.9885282020616312 1.0 1.0 37 Q9Y237,O00170,Q15257,Q96BP3,P62942,Q9BV86 6 +Nucleoside diphosphate metabolic process 0.2385697377175166 0.0143324377412477 0.988564760711065 1.0 1.0 48 P22392,P23921,P15531,P27708,P85037,P08237,Q96DE0,P17858,Q9UKK9 9 +Actin filament bundle organization 0.2319869265535651 0.0143306534818515 0.988566184197895 1.0 1.0 45 Q9Y613,O43795,Q16512,P63167,Q13464,P42345,O75116,P35241,P60953,P49407,Q7Z460,Q9UHB6,Q9UQB8,Q13618 14 +Response to tumor necrosis factor 0.2029614615869046 0.0142650383609541 0.9886185321388286 1.0 1.0 38 P98170,P28482,P42574,Q92974,P63241,P49327,Q96BN8,Q16822,Q14790,Q6P2Q9,Q9H6S0,O15111,Q13418 13 +Epithelial cell proliferation 0.2252594078205238 0.0142565986520527 0.9886252653675522 1.0 1.0 43 P22392,Q15648,P09429,P28482,P15531,P21359,P40763,Q00534,P78527,Q9Y5V3 10 +Hindbrain development 0.1399585769114384 0.0142409088758304 0.988637782727017 1.0 1.0 35 Q06124,P63167,P27695,P31939,P12277,P46109,Q00535 7 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.2372844453587357 0.0142059621948391 0.9886656633238796 1.0 1.0 75 P49841,P43490,P46109,P31751,Q8TBX8,Q92600,P51452,P40763,Q96F07,O14654,Q06124,P42574,O00443,Q8IXJ6,P11802,Q9UQB8,Q14155,Q16512,P27695,P28482,P22681,P46940,Q9Y5X3,Q99816 24 +Negative regulation of immune system process 0.2419679095629797 0.0141648385510513 0.9886984719432066 1.0 1.0 51 P09429,Q9UIV1,P30046,P14174,P51452,P42574,P21359,Q13315,Q00534,Q9HCL2,Q9Y3I1 11 +Regulation of actin filament organization 0.2473098424622382 0.0141361706024415 0.9887213433668268 1.0 1.0 66 P31146,O75116,Q9Y2A7,Q7L576,P35241,Q13045,Q96F07,Q8WUW1,P42345,P47755,Q9Y613,Q9UQB8,Q9BPX3,Q16512,P63167,Q13464,P60953,Q7Z460,Q9UHB6,O00401 20 +Carbohydrate homeostasis 0.2250315065212481 0.0138528676075672 0.9889473643179132 1.0 1.0 45 Q06124,P06737,P42785,P51532,P22059,P40763,P85037,P62753,P08237 9 +Phagocytosis 0.2007623700399327 0.013850091656595 0.9889495789938676 1.0 1.0 40 Q16512,Q9NT62,P09429,Q14185,P50570,Q92614 6 +Viral gene expression 0.1946022420858023 0.0137323794534842 0.9890434908119404 1.0 1.0 40 Q9ULC4,P49841,P41214,O14646,P51532,Q14152,Q4G0J3,Q99873 8 +Skin development 0.2180695545580805 0.0136832973095002 0.9890826490176516 1.0 1.0 44 Q92908,P22392,Q15648,Q13464,O00203,O75116,P42574,P21359,Q5C9Z4,P18074,Q99816 11 +Regulation of protein secretion 0.212121476718894 0.0136329590274395 0.9891228094096968 1.0 1.0 43 Q06124,O75592,P35580,Q08209,Q92614,O00429,P22059,Q16850,P53985,O95486,P08237,P04035,Q15334,P17858,Q9Y5K6 15 +Regulation of nervous system development 0.2418149718518822 0.0134012672168701 0.9893076558401672 1.0 1.0 69 Q08209,Q13614,P21359,Q00535,Q9P2D1,Q7L576,Q15058,Q14999,Q9UPN3,Q9UBS4,P63172,Q96P11,P49917,P42345,Q8TEW0,Q96N67,Q8IXJ6,Q9UQB8,O14744,P43034,P27695,Q9P265,P46821 23 +Adaptive immune response 0.2224915522914124 0.0133482340876598 0.9893499663706636 1.0 1.0 47 Q16512,P49917,P52701,P09429,Q9UDY8,P42345,P36915,P40763,Q96FW1,Q96FZ2,Q6GQQ9 11 +Dna templated transcription elongation 0.2118736814219589 0.013270339162609 0.9894121120243162 1.0 1.0 45 O75909,Q14241 2 +Ribonucleoside diphosphate metabolic process 0.2108169957774672 0.0132374857121243 0.9894383229829352 1.0 1.0 45 P04075,P14618,P23921,Q9BRR6,P27708,Q01813,P09972,P11172,P40763,P17858,P85037,P08237,Q96DE0,P06744,P18669,Q9UKK9 16 +Response to starvation 0.2198872559916029 0.0132246470108209 0.9894485658878792 1.0 1.0 47 P28482,P22681,P42345,O95352,Q6PKG0,P08243,P49327,Q99570,P85037,Q9P2J5,Q92616 11 +Response to wounding 0.224593566348634 0.0132081904259831 0.989461695196122 1.0 1.0 80 P00374,Q16512,O14965,Q9UPN3,P42345,P42574,O00203,Q99707,Q9C0E8,Q8WUX9,P35579,P42785,P21359,Q00535,Q7Z460,P46821 16 +Positive regulation of nervous system development 0.1515990793105575 0.0131746193745386 0.9894884786893168 1.0 1.0 42 P49917,Q15382,P27695,Q9UPN3,Q14999,P61160,P42345,Q9UPY3,Q9UQB8,Q9H2U1,O14744,P46821,Q7L576,P43034 14 +Positive regulation of neurogenesis 0.1515990793105575 0.0131746193745386 0.9894884786893168 1.0 1.0 42 P49917,Q15382,P27695,Q9UPN3,Q14999,P61160,P42345,Q9UPY3,Q9UQB8,Q9H2U1,O14744,P46821,Q7L576,P43034 14 +Response to carbohydrate 0.162586742583625 0.0130343561923702 0.9896003829077924 1.0 1.0 43 P17612,P42574,Q08209,P51532,P22059,P49770,Q13144,P17858,P46821,Q9HCL2 10 +Positive regulation of cellular protein catabolic process 0.2226400728950544 0.0130087201117556 0.9896208358066388 1.0 1.0 49 O75925,O14965,P49841,O60826,Q06787,P35241,Q8IXJ6,P53350,Q9ULT8,O75832 10 +Cytoskeleton dependent cytokinesis 0.2035769367957045 0.0128875095882027 0.9897175397052074 1.0 1.0 46 Q9H8V3,Q8WWK9,P35580,Q14999,Q13464,Q13432,O75116,Q15019,P40818,Q8WUX9,Q14674,Q96Q89,P61586,P53350 14 +Regulation of viral process 0.2107616640967574 0.0127278580003871 0.9898449127947346 1.0 1.0 48 P78362,Q9UIV1,Q6PKG0,Q16513,Q4G0J3,Q96SB4,Q99816 7 +Negative regulation of protein catabolic process 0.187114107124176 0.0126690156691476 0.9898918583971968 1.0 1.0 46 Q96QK1,P78559,O75592,P68400,Q13464,P62081,P04035,P46379,Q13526,Q8IXJ6,P19784,Q16850,P46777,O60493,O94966 15 +Negative regulation of dna metabolic process 0.1965314317602302 0.0126077744660204 0.9899407179053524 1.0 1.0 47 P52701,P09874,Q8IZH2,P20585,O95071,Q9UBB9,Q13315 7 +Male gamete generation 0.2324998370949958 0.0125234128877304 0.9900080233923942 1.0 1.0 74 P52701,P30307,P25440,O00203,P50570,Q8NHU6,Q14997,P19784,O95248,Q6P6C2,Q4G0J3,Q13315,Q96SB4,Q14353 14 +Positive regulation of protein kinase activity 0.2375272187178066 0.0123760045566629 0.9901256291092636 1.0 1.0 63 Q16512,Q96JP5,P42345,P14174,P20248,Q7KZI7,Q00535,O75909,P14635,P46940,Q9UDY8,Q15334,Q9UER7,Q9Y5V3,O75832 15 +Regulation of dna biosynthetic process 0.1848323570181078 0.0123384767059253 0.990155569715892 1.0 1.0 48 Q8IZH2,Q13535,Q13315,Q96HR8 4 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.2204384418817576 0.0122586490778467 0.9902192581310778 1.0 1.0 53 P78559,O14965,P49841,O14980,O75925,Q92990,Q8IXJ6,P53350,Q9ULT8,O75832 10 +Protein localization to chromosome 0.2034090623263661 0.0122352219701303 0.9902379488568892 1.0 1.0 50 P50748,Q8WUX9,Q7Z5K2,Q13535,P53350 5 +Protein acetylation 0.2351913619935072 0.0122339854167359 0.990238935409912 1.0 1.0 61 Q9UPT9,Q14CX7,Q5VZE5,Q96L91,P49407,Q9Y4A5 6 +Cytokinesis 0.2350634534445403 0.012008703154818 0.990418671443617 1.0 1.0 65 Q13432,O75116,Q13526,O14965,Q15058,Q14999,P61586,Q99741,Q9H8V3,Q8WWK9,Q8WUX9,Q96Q89,Q16513,Q9NR09,P35580,Q13464,P35579,Q15019,P60953,P40818,Q14674,Q99570,P53350,Q13618 24 +Positive regulation of growth 0.2211216868467846 0.0119855461965713 0.9904371466934484 1.0 1.0 55 Q92908,P68400,Q9P2D1,Q9Y263,Q9UPN3,Q6PJG6,Q04637,P60953,Q7Z4V5,Q15418,P61586,P46821,Q7L576,Q9HCL2,O75832 15 +Regulation of dna recombination 0.20473114570451 0.01178765948201 0.990595026293624 1.0 1.0 53 P52701,Q96L91,Q7Z4V5,P20585,Q9H4L7,Q9Y4A5,P18074 7 +Response to temperature stimulus 0.1593072445691303 0.0116483731201871 0.9907061531013844 1.0 1.0 52 P49841,P17612,P42345,Q53FT3,P21359,P49770,Q13144,Q13535,Q13315,Q9UER7 10 +Spindle assembly 0.1918527881170226 0.0116135055354414 0.9907339715272394 1.0 1.0 53 O96017,O14965,O95067,Q9BW19,O43670,Q8WUX9,Q9Y295,Q96CW5,Q7Z4H7,Q9BSJ2,Q14204,P61586,Q7Z460,P53350,Q15555,Q9BT25,O00139 17 +Regulation of developmental growth 0.2001516836145519 0.0115556256385637 0.9907801499046096 1.0 1.0 54 Q92908,Q9UPN3,Q9Y263,P50570,Q99956,Q00535,P40763,Q9P265,P46821,O60271,Q9P2D1,Q9HCL2,Q14353 13 +Positive regulation of protein catabolic process 0.2304619917575522 0.0114919093137025 0.9908309848010004 1.0 1.0 65 P49841,P68400,O95352,Q13190,O14965,O43847,P46379,P35241,Q9BW61,Q96QK1,Q7Z6Z7,Q8IXJ6,P14735,Q9ULT8,P63244,O75832,O75925,O60826,Q06787,Q9UNN5,P53350,Q13620 22 +Activation of immune response 0.1859526193954161 0.0114154200821394 0.9908920103749224 1.0 1.0 54 Q96EP0,P09429,P28482,P55212,P51452,Q13144,Q9UDY8,P78527 8 +Negative regulation of phosphorylation 0.226903440912111 0.0114012954130656 0.9909032794969372 1.0 1.0 74 P46109,P42771,P21359,Q8TBX8,Q12923,P51452,P40763,P78527,Q9Y3I1,P42574,Q8TEW0,Q8IXJ6,O60271,P31689,P47897,Q16512,P63167,Q13464,Q04637,P22681,P53350,P04035,O95373,O00410,Q99816 25 +Positive regulation of cell development 0.2218658544168204 0.0110919648869335 0.9911500739383396 1.0 1.0 62 Q14185,P46109,Q7L576,O14965,Q14999,Q9UPN3,P78527,P49917,P42345,P50570,Q8IXJ6,Q9UQB8,O14744,Q14155,P43034,Q13418,P27695,P60953,P46821 19 +Positive regulation of cell projection organization 0.2268986619163286 0.011010630217982 0.9912149656521644 1.0 1.0 69 P49841,P07737,Q9Y2A7,Q7L576,Q8NCA5,Q14999,P61160,Q9UPN3,P42858,Q15555,Q8WUW1,Q9H4M9,P42345,P50570,Q9NZQ3,Q7KZI7,Q9UQB8,O60493,Q14155,P43034,P27695,Q06787,P60953,P46821,Q15334,O00401 26 +Sensory organ development 0.2197045011589721 0.0109751883035496 0.9912432424998978 1.0 1.0 62 Q9UM54,O75569,Q15648,Q06124,P28482,Q9Y4P1,P83731,Q8NHU6,Q15042,P21359,P51532,P20248,A1X283,Q9P2D1 14 +Response to insulin 0.2017626028268364 0.010973344874469 0.9912447132549328 1.0 1.0 58 Q06124,P07741,P49841,P09874,P43490,O15357,P07814,P42345,O00443,P31751,Q9Y5X3,Q8TBX8,P11802,Q9UQB8,P78527,O14654 16 +Phospholipid biosynthetic process 0.2104537446591879 0.0107373341340449 0.991433011485756 1.0 1.0 61 O96017,Q13907,P35790,O15357,O00443,Q13614,P42356,Q01968,Q08AM6,Q99570,Q13315,Q9HCL2,Q8NCE2 13 +Endosomal transport 0.2218938893002811 0.0106990901576866 0.9914635240113434 1.0 1.0 66 Q7Z3T8,Q13190,Q4J6C6,Q9P2R3,Q14203,O75436,Q9H269,Q9H4M9,Q9UBC2,O00203,Q8WUX9,Q00610,O60271,Q13501,O60826,O14617,Q9H223,Q92538,Q9UID3,Q9Y5X3,Q2M389 21 +Regulation of neurogenesis 0.2110355639484413 0.010619500620624 0.991527023666614 1.0 1.0 62 Q08209,P21359,Q00535,Q9P2D1,Q7L576,Q14999,Q9UPN3,Q9UBS4,P63172,P49917,P42345,Q96N67,Q8IXJ6,Q9UQB8,O14744,P43034,P27695,Q9P265,P46821 19 +Positive regulation of intracellular protein transport 0.192622458066301 0.010554237880328 0.9915790928813952 1.0 1.0 60 Q96EP0,P49841,P17612,Q7Z6Z7,P60953,P30419,P31751,O95071,Q00535,Q96Q89,P19784,Q9Y6B6 12 +Cellular carbohydrate metabolic process 0.2127280204500402 0.0104216051534353 0.9916849126662995 1.0 1.0 64 P49841,Q13614,P31751,Q01968,P62136,Q9UNI6,P06737,P40763,P35573,O43505,Q9UJ70,Q15185,P46976,P11216,P13807,P18669,Q00796,Q93100,P85037,Q9Y223,P08237 21 +Recombinational repair 0.1936756476185927 0.0104159931941642 0.9916893901189344 1.0 1.0 61 Q96T76,O60921,P61160,P09874,Q7Z4V5,P46063,P35244,P54132,Q96L91,Q68E01,Q9Y620,Q13315,Q9Y3Z3,O00487,Q9Y4A5,P33993,A6NHR9,P33992 18 +Cytosolic transport 0.201873856744452 0.0103898213792793 0.9917102710760546 1.0 1.0 62 Q7Z3U7,P36507,P31146,Q13614,O95782,Q4J6C6,Q13190,P57737,Q9P2R3,O75165,Q14203,P35241,O75436,Q96QK1,O94832,Q00610,O14976,O60271,P28482,Q99570,Q5VIR6,Q92538,Q9UID3,Q9Y5X3 24 +Negative regulation of transferase activity 0.2080133831257641 0.0100066034027907 0.9920160188812064 1.0 1.0 66 P49841,P42771,P21359,Q8TBX8,P62081,P51452,P62841,P61927,P46777,Q9Y3I1,P42574,P60866,Q14240,P31689,P47897,Q16512,P22681,P53350,P04035,O95373,O00410,Q99816 22 +Microtubule cytoskeleton organization involved in mitosis 0.2164603543433333 0.0099698349101195 0.992045354430471 1.0 1.0 74 O96017,O14965,Q14008,Q15398,Q15257,Q8WUX9,P42858,Q00610,Q14674,Q14204,Q9UH99,P14635,Q7Z460,P53350 14 +I kappab kinase nf kappab signaling 0.177124527645531 0.0098522939578241 0.9921391339354596 1.0 1.0 64 O15111,Q96EP0,O60826,Q9Y3E0,O75116,Q9UDY8,Q13501,P62942,Q6GQQ9 9 +Immune response regulating signaling pathway 0.1950850293044644 0.0098494046639608 0.9921414391465742 1.0 1.0 65 Q96EP0,P09429,P28482,O00203,P51452,Q01804,Q96BN8,Q13144,Q9UDY8,Q14258 10 +Endoplasmic reticulum to golgi vesicle mediated transport 0.1809899489118921 0.0095703426275791 0.992364087940092 1.0 1.0 66 Q9UBF2,Q96JB2,P53618,Q92538,Q9Y296,O95070,Q9Y6B6 7 +Muscle cell differentiation 0.1675024551983011 0.0093710554287848 0.9925230889880216 1.0 1.0 67 Q92908,P17655,P67809,P42345,P42574,P35579,Q7Z4V5,Q92990,Q13045,Q86TU7,P26358,O60271 12 +Intracellular receptor signaling pathway 0.1910372549479491 0.0093686591149751 0.9925250008858846 1.0 1.0 68 Q16512,Q15648,P09874,Q96EK7,A5YKK6,P42785,P10589,P51532,Q13309,O95071,Q96BN8,Q9UER7,Q14258 13 +Negative regulation of hydrolase activity 0.1845156460615939 0.0092996690255057 0.9925800446151704 1.0 1.0 68 P49841,Q9UHD1,P68400,O00170,O75116,Q9P258,P98170,Q9NVX2,Q15554,P35241,Q15392,P29375,Q9GZT9,Q04323,P30044,Q15257,Q15418,Q5JVF3,P61221,Q9P0V3,P06744,P62942,P78318,Q9NR09,Q96K76,Q13464,Q96GX5,Q14684 28 +Regulation of neuron projection development 0.1959006974299404 0.0090526330195492 0.9927771425316152 1.0 1.0 71 P49841,P46109,Q08209,Q13153,P10589,Q00535,Q7L576,Q6SZW1,Q14999,P61160,Q9UPN3,Q6IBS0,P61586,Q9Y3I1,Q9H4M9,Q05086,Q9NZQ3,Q7KZI7,O14976,O60493,Q9UQB8,P43034,Q16512,Q13555,Q9H2U1,Q9P265,P46821 27 +Inflammatory response 0.1774515829840571 0.0089573887083516 0.992853133415874 1.0 1.0 70 Q8NE71,P09429,Q9Y263,O00203,P14174,P42345,P30046,P49327,Q96BN8,Q13315,O15111 11 +Taxis 0.1440044227934505 0.0088930451243497 0.9929044701233584 1.0 1.0 70 P09429,O75592,P28482,P30046,P14174,P51452,P83731,Q00535,Q92538,Q9BPU6 10 +Regulation of proteasomal protein catabolic process 0.1825405817932109 0.0088493486952365 0.9929393334576404 1.0 1.0 71 P78559,O14965,P49841,O14980,Q06787,P17612,O75925,P61289,Q92990,Q8IXJ6,P53350,Q9ULT8,O75832 13 +Regulation of response to biotic stimulus 0.1898247227168696 0.0088037272598078 0.9929757326786888 1.0 1.0 72 Q06124,Q16512,Q96EP0,Q9UIV1,P09429,P55212,P14174,Q9NW08,Q8IXJ6,Q9BUI4,Q9UII4,P78527 12 +Exocytosis 0.1776643169864462 0.008521954206975 0.993200546610733 1.0 1.0 73 Q16512,P49841,P27695,Q06787,P22681,P35579,O00443,Q15042,Q8TAG9,Q00535,Q7Z460,Q15334,Q9Y6D5,Q99816 14 +Gland development 0.1779237902041597 0.008241207844733 0.9934245419298572 1.0 1.0 75 Q15648,P07741,Q9HAU5,P31751,P21359,P49327,O14965,P15531,P62841,Q92908,Q15418,P19784,Q13315,O14744,O75592,O95067,P28482,P60953,Q13618,P04818 20 +Positive regulation of intracellular transport 0.1763577062283358 0.0080870277764822 0.9935475557260998 1.0 1.0 76 Q9H4M9,Q96EP0,P49841,P17612,Q7Z6Z7,P60953,P35241,P30419,P31751,Q13614,O95071,Q00535,Q14204,Q96Q89,P19784,Q9Y6B6 16 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d636cb43ebcee4efe3768053b172b5ed0c59232f --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B 1 b cell differentiation", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle myoblast proliferation", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac vascular smooth muscle cell differentiation", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Dipeptide transmembrane transport", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G1 to g0 transition involved in cell differentiation", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isg15 protein conjugation", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L kynurenine metabolic process", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of torc1 signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide import across plasma membrane", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic a cell differentiation", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper 17 cell differentiation", "Positive regulation of t helper 17 type immune response", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride lipase activity", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of antimicrobial humoral response", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell division", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 17 cell differentiation", "Regulation of t helper 17 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to pheromone", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sinoatrial node development", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell antigen processing and presentation", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transforming growth factor beta2 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRK1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPK", "CENPV", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NEMP1", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLE4", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512B", "ZNF598", "ZNF638", "ZNF703", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["AAR2", "AARSD1", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD14B", "ABHD5", "ACACA", "ACLY", "ACO1", "ACOT7", "ACOX1", "ACTR10", "ACTR2", "ADA", "ADPGK", "AFDN", "AGL", "AGPS", "AHCY", "AIMP2", "AIP", "AK6", "AKAP9", "AKR1A1", "AKT1S1", "AKT2", "ALDOA", "ALDOC", "ALG12", "ALG5", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC4", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "AP1B1", "AP1M1", "AP2A1", "AP2A2", "AP2M1", "AP3B1", "AP3D1", "APEX1", "APRT", "ARF4", "ARF5", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARL3", "ARRB1", "ASCC3", "ASNS", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP6V1D", "ATP6V1G1", "ATR", "AURKA", "B4GAT1", "BAG3", "BAG6", "BAIAP2", "BAZ1B", "BAZ2A", "BBS9", "BCAS3", "BCOR", "BICD2", "BIRC6", "BLM", "BMS1", "BPTF", "BRAT1", "BRD2", "BRK1", "BTAF1", "BTF3", "BUB1", "BUB3", "BUD23", "C17orf75", "C21orf59", "CAD", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CAPN2", "CAPZA2", "CAPZB", "CARHSP1", "CARS", "CASP3", "CASP6", "CASP8", "CASP8AP2", "CBL", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT4", "CD2AP", "CDC25C", "CDC34", "CDC42", "CDC5L", "CDC6", "CDCA2", "CDH2", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDKN2A", "CERS2", "CFL2", "CHAC2", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP7", "CHORDC1", "CHST14", "CHTOP", "CHUK", "CIAO1", "CKAP2", "CKAP5", "CKB", "CLASP1", "CLIC1", "CLIC4", "CLK3", "CLTC", "CLUH", "CMTR1", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "COG2", "COG3", "COPA", "COPB1", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "CORO1A", "CORO7", "COX15", "CPNE1", "CRKL", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTH", "CTPS1", "CTR9", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CXADR", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAXX", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DDA1", "DDB1", "DDT", "DDX1", "DDX21", "DDX28", "DDX56", "DDX6", "DERL1", "DHCR24", "DHFR", "DHRS7B", "DHX29", "DHX34", "DHX36", "DHX37", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIP2B", "DIS3", "DKC1", "DLG3", "DLGAP5", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB11", "DNAJC13", "DNAJC2", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL5", "DRG1", "DST", "DSTN", "DUS1L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLT1", "ECT2", "EDC3", "EDRF1", "EEF1A2", "EEF1G", "EEF2", "EGLN1", "EHD1", "EHD4", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B2", "EIF2B5", "EIF2D", "EIF3A", "EIF3D", "EIF4A2", "EIF4G1", "EIF4G3", "EIF5A", "EIF5B", "ELAC2", "ELOA", "ELOC", "ELP1", "ELP3", "EP400", "EPB41L5", "EPPK1", "EPRS", "EPS15L1", "ERCC2", "ERCC6L", "ESPL1", "EXOC2", "EXOC6", "EYA3", "EZR", "FADS2", "FAF1", "FAM120B", "FAM129B", "FAM208A", "FAM49B", "FAM98A", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO22", "FBXO7", "FERMT2", "FHOD1", "FKBP1A", "FLII", "FLOT2", "FMR1", "FN3KRP", "FOXK1", "FSCN1", "FTSJ1", "FTSJ3", "G6PD", "GAK", "GALK1", "GALM", "GAMT", "GAPDH", "GART", "GATA6", "GBF1", "GCAT", "GCLC", "GCLM", "GCN1", "GDI2", "GEMIN4", "GET4", "GFPT1", "GIGYF2", "GLDC", "GLMN", "GLRX", "GMFB", "GMPR2", "GMPS", "GNE", "GNL1", "GNPAT", "GOLGA5", "GOLT1B", "GOPC", "GOT1", "GPAM", "GPATCH4", "GPD1L", "GPHN", "GPI", "GPS1", "GSK3B", "GSTM2", "GSTM3", "GSTO1", "GTF3C1", "GTF3C2", "GTPBP1", "GYG1", "GYS1", 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0000000000000000000000000000000000000000..58d67f7fd34e1de46b3bdd590cb386142e670a49 --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,25 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Ribosome 58 134 5.309850349693786 1.0971528521030153e-07 55.980582524271846 138.4247572815534 -0.8588609779449204 0.4198796746336922 18.0091565612889 6.601093517039386 1.5926376724246476 0.3624017888625265 0.0660745674766155 3.1145862927174137e-07 9.15397401941495e-09 2.883167652569677e-23 +Ribosomal subunit 49 117 5.205840118548462 1.9312087085874376e-07 51.269417475728154 121.31067961165049 -0.8787798235149152 0.3945201412304035 16.491031297432507 6.024269888830331 1.7251057442328237 0.3662365802061124 0.0459448705321983 5.356395818737246e-07 2.1217927791225323e-08 8.643282661819595e-23 +Intracellular protein containing complex 79 256 4.180101271117269 2.913793031100731e-05 65.0 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0.7560556131321781 0.3181061673603851 0.0901161496803885 0.4364043253687706 0.0730198011856182 0.0753659731620057 +Ribonucleoprotein granule 32 114 2.996442993050831 0.0027314930466024 31.388349514563107 108.0873786407767 -0.1052892902919536 0.6662905949668418 12.160123442229802 8.26662114574696 0.8202737617387182 0.3209230511652521 0.278388638107537 0.344196256211293 0.0164846769888668 5.002862797581704e-05 +Microtubule 56 137 2.624856878547648 0.0086685396169758 34.04368932038835 124.58252427184466 -0.1363347466122726 0.6676070174891633 13.640247199756626 12.902565615151678 0.8574275819666219 0.3237907918506225 0.4835877400917083 0.6316843954923629 0.1960169709959855 0.0019754982855585 +Centrosome 51 171 2.5954565960693268 0.0094465333351076 36.95873786407767 159.5509708737864 0.0251919200764879 0.7769899257829331 12.357370598786408 19.747061328112576 0.6556926300255246 0.297859525552804 0.230683182755797 0.5505701886413982 0.1192963551020896 0.0875028040438024 +Saga complex 2 5 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-0.1991917740572248 0.672044075129004 11.981767291657192 11.69636093329509 0.7227206919436855 0.3024789588236066 1.0 0.960046062481476 0.6908940859684929 0.3354753663430884 +Trna methyltransferase complex 3 6 2.2934426986473597 0.021822530760182 2.1407766990291264 4.092233009708738 -0.5236899498608133 0.4932531654691522 1.2025811151378485 1.117485850164612 0.8767550219547782 0.3024833681773016 1.0 1.0 0.0004628530549595 0.0001735559058557 +Pole plasm 2 6 2.277638234076623 0.0227481405382317 1.5631067961165048 4.400485436893204 0.4130281049837241 0.5312127180989363 1.214155209225631 0.9016165402820902 0.8811647692216603 0.3113002563791068 1.0 1.0 0.0010713621736615 0.0077568745967145 +Crd mediated mrna stability complex 0 6 2.261832620153986 0.0237077466255772 1.9733009708737863 5.910194174757281 0.3271204777544745 0.5413593466387774 1.5206557657669346 0.2859033735288774 0.8816813816887278 0.3185396579284427 0.028497516818446 0.0563150378970086 0.1373795195898598 0.2591162943571684 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0.7432576252185813 0.8344273461054379 0.3024483994651719 1.0 1.0 0.1373795195898598 0.2591162943571684 +Rna polymerase iii transcription regulator complex 1 5 2.052418928845269 0.0401289664922184 2.3325242718446604 4.572815533980583 -0.2899563152804711 0.5489947521487886 1.2936027949716449 0.7419724662880485 0.837439537671932 0.3014795701682093 1.0 1.0 0.2373820829012167 0.4230365159515766 +Ribonuclease p complex 2 7 2.036810788030645 0.0416690068087994 2.8228155339805827 5.803398058252427 -0.6362953992499971 0.452459923990748 1.554874525875 1.050976479278309 0.8243826959556784 0.2967837832137859 0.0017062060788896 0.0066572828402184 0.0033939033653995 0.0228394808772788 +Cytosolic large ribosomal subunit 30 46 1.9707552550138543 0.0487518769816772 24.944174757281555 46.19660194174757 -0.9606653080216496 0.3073733017858688 8.750550054752102 0.6518741515897012 1.9361311533291576 0.3576780745044947 0.0266825716175236 6.555605030826267e-07 2.7010604646458125e-10 2.527929711666217e-23 +Microtubule cytoskeleton 119 373 1.9614615312240908 0.0498252082687855 85.69174757281553 346.7378640776699 -0.286278027961305 0.6698830189998075 27.858512666938093 38.40338050579385 0.8166283240500035 0.3433950042893994 0.2145628670989967 0.5231771299851059 0.2115263252673843 0.0278948883034034 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f51075a2eee02289e8e1221ac7e9ff6fa1f656f1 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 906, + "title": "Average number of proteins per term", + "value": 29.26158940397351 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d7101a011463401aee176711924471d591355278 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..86da30e26e4c748f0a527ef8bab5c046169ffaf6 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,317 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosome 0.4809236122458631 5.309850349693786 1.0971528521030153e-07 9.93971136339371e-05 9.940204840143916e-06 134 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,Q5F1R6,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,Q0VDF9,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,Q7Z478,P62906,P62753,Q92616,P50914,P62910,P20290,Q9HD33,P27695,P26373,P62266,P18124,P62277,P61513,P39023,Q6PKG0,P61254,P62899,P82675,Q9NP92,Q9Y3U8 58 +Ribosomal subunit 0.4878856675772205 5.205840118548462 1.9312087085874376e-07 0.000174952219969 1.590613718172071e-05 117 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,Q7Z478,P62906,P62753,P50914,P62910,Q9HD33,P26373,P18124,P62266,P61513,P39023,P61254,P62899,P82675,Q9Y3U8 49 +Intracellular protein containing complex 0.3309903854224514 4.180101271117269 2.913793031100731e-05 0.0260539329144677 0.0018856403472695 256 Q9UM54,Q9UPT9,Q14185,Q9GZZ1,Q15386,P49721,Q5VYK3,O95163,Q14997,Q5TAQ9,Q92499,Q9Y3I1,Q96P16,Q07864,Q9H9T3,O14802,O43242,P28066,O75832,Q06787,Q5VZE5,Q9NW08,P49720,P68400,Q5TBB1,Q8TF05,Q92990,P28340,Q9HAD4,Q15369,Q9Y4A5,Q92600,Q14CX7,P17612,P25787,P20618,Q96L91,Q9BW61,P78527,Q9NT62,Q9UJX5,P19784,Q13200,P49005,Q9Y6J9,Q14738,Q13618,P28072,A5YKK6,Q08209,Q7L576,Q8NCA5,Q92759,Q9GZS3,Q9NZL9,Q14999,Q13309,Q6NTF9,Q9Y296,P67870,P63151,P18074,Q96P70,Q15257,Q6W2J9,Q96EP0,Q9UIV1,Q13616,O00170,Q15008,Q9BUI4,Q9UL63,Q86VP6,Q96BN8,P49917,P42345,Q13555,P61289,O43396 79 +Cytosolic ribosome 0.6789028557826247 3.2114729085617326 0.0013205642123272 0.6979678633850723 0.0394491728428539 79 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,Q7Z478,P62906,P62753,P50914,P62910,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9Y3U8 47 +Transferase complex 0.3001791771182331 3.207244041046648 0.0013401325762472 0.7032823926307826 0.0394491728428539 243 Q96EP0,Q9UPT9,P62314,Q96FX7,Q13616,O75909,P28340,Q69YN4,Q15369,Q9BUI4,Q9Y4A5,Q9UL63,Q9UBP6,Q86VP6,P57081,Q14999,Q14CX7,Q96L91,Q13309,Q6NTF9,Q5TAQ9,Q9NYV4,Q00534,P78527,P18074,Q9Y3I1,Q9NT62,Q07864,Q96P70,O00443,Q8TEW0,Q08AM6,P14635,O14802,Q9UJA5,P17858,O15111,Q9HCK8,P49005,O95067,Q5VZE5,Q9NW08,Q9Y6J9,P61803,P08237,Q6W2J9,Q6UXN9 47 +Microtubule organizing center 0.3096802117362556 3.176952991524215 0.0014883115780111 0.7406079651755262 0.040473961341566 214 P49841,Q3SYG4,Q15398,Q99504,O75116,Q92547,Q13526,Q9BSJ2,Q12873,Q9Y5Y2,Q9Y6D5,Q9Y5K6,Q5SW79,Q99661,Q14203,O14965,Q8NI35,Q14999,Q9Y5K8,P17612,P62081,Q5VYK3,O60610,P42858,Q03518,Q13045,Q14839,Q9Y496,Q14204,P53985,Q00534,Q8WWK9,Q5T4S7,Q9Y3D8,Q9BZH6,P50570,Q9P1Y5,Q8IXJ6,Q9Y696,Q96Q89,P14635,O43237,Q96CW5,Q13315,Q16513,O60271,Q9BT25,Q9BPX3,Q9NR09,Q14155,P43034,Q16512,P63167,O95067,P27695,Q13464,Q9BW19,Q6NXR4,P28482,P60953,Q14008,Q14674,Q96GX5,Q99996,Q7Z4H7,Q7Z460,Q7Z5K2,P53350,Q9BTW9,Q13618,Q99816 71 +Ribonucleoprotein granule 0.3542696514116877 2.996442993050831 0.0027314930466024 0.9160990820984012 0.0478185365955203 114 Q9UIV1,P67809,O75116,Q8IZH2,A5YKK6,P62701,Q5TAX3,P25787,P26196,Q02878,Q9NUL7,P46779,Q9Y520,Q96F86,Q92499,Q9HCE1,P49917,Q86TB9,Q8NHU6,P62753,Q13501,Q14258,Q06787,Q13464,Q04637,Q96C86,P60953,Q6PKG0,P46940,Q9Y2V2,Q9H6S0,Q9HAU5 32 +Lewy body 0.8951290246949404 2.968639898835696 0.0029912090627144 0.933735213910681 0.0478185365955203 3 Q9Y3I1 1 +Mismatch repair complex 0.8853387385118979 2.9056601420928367 0.0036647926213144 0.9640778481246526 0.0520648466299125 4 P20585,P54277 2 +Phosphatidylinositol 3 kinase complex class iii 0.851686063861526 2.793353913785785 0.0052164584852021 0.9912480715274464 0.0647412518848374 2 Q08AM6 1 +Elongin complex 0.8539094731145762 2.7828354850175896 0.005388612233677 0.9925182155653132 0.0659740903204242 3 Q14241 1 +Phosphatidylinositol 3 kinase complex 0.851940298507466 2.7738555662460165 0.0055396266658056 0.9934798293729964 0.0669186901229322 3 Q08AM6,O00443 2 +Microtubule 0.3276268117756227 2.624856878547648 0.0086685396169758 0.999624756324048 0.0818201738213598 137 P36507,O43670,Q13330,O15344,Q99426,Q00535,Q9BSJ2,Q9P258,Q6NUK4,Q9Y6D5,Q5SW79,Q99661,Q14203,O00139,O14965,Q15058,Q9UPN3,Q9BUF5,P50748,Q13885,Q9Y496,Q14204,P63172,P04350,O94967,Q8WWK9,P50570,Q9P1Y5,Q8WUX9,O00429,Q00610,Q8IXJ6,Q96Q89,Q96CW5,O43237,Q9UQB8,Q9BT25,O60333,P43034,P78559,P63167,P46821,Q14008,Q9BW19,P29372,Q92974,Q9H6H4,P46940,Q7Z4H7,Q14152,Q7Z460,Q86TI2,P53350,Q9BTW9,Q13618,Q66K74 56 +Centrosome 0.3076548974669197 2.5954565960693268 0.0094465333351076 0.9998157542247216 0.0850116335230338 171 P49841,Q3SYG4,Q15398,Q99504,O75116,Q9BSJ2,Q12873,Q9Y5Y2,Q9Y5K6,Q5SW79,Q14203,O14965,Q8NI35,Q14999,Q9Y5K8,P17612,P62081,Q5VYK3,Q14839,Q03518,Q13045,Q9Y496,Q14204,P53985,Q00534,Q5T4S7,P50570,Q9P1Y5,Q8IXJ6,Q96Q89,Q96CW5,P14635,O43237,Q16513,Q13315,O60271,Q9BT25,Q14155,P63167,O95067,P27695,Q14008,Q6NXR4,P60953,Q14674,Q96GX5,Q99996,Q7Z460,Q7Z5K2,P53350,Q9BTW9 51 +Golgi transport complex 0.8146891047511001 2.5815536847984855 0.0098356692452694 0.9998709394939188 0.0854403979242336 4 Q96JB2,Q14746 2 +Equatorial microtubule organizing center 0.803939122649951 2.573578480635401 0.010065281646816 0.9998953981009452 0.0854403979242336 2 Q96CW5 1 +Nucleolar ribonuclease p complex 0.808401842334195 2.5728563032195284 0.010086307562005 0.9998973917503504 0.0854403979242336 3 O75818 1 +Cyclin cdk positive transcription elongation factor complex 0.8043774405604969 2.5332179581628664 0.0113020652559518 0.999966298747692 0.0901351527621137 4 O75909 1 +Saga complex 0.8038160274240901 2.5106207341704043 0.0120519101942093 0.9999830520166406 0.0949480924865538 5 Q9UPT9,Q9Y4A5 2 +Meiotic spindle 0.7922133602205325 2.4758580822105243 0.0132916400290674 0.9999945667476012 0.1029250074045737 4 Q8IXJ6 1 +Chromosomal region 0.3014821960176719 2.4572529109468517 0.0140004084228553 0.9999971665082502 0.1040753374793758 171 P09874,Q6P1K2,Q13535,P28340,P26358,Q9UBD5,Q9P258,Q9UER7,P42695,Q15021,P50748,Q14839,Q9UBB9,P78527,Q8IWS0,Q29RF7,Q8WUX9,Q8IXJ6,P14635,O43237,Q9NTJ3,Q13315,Q9BPX3,O96017,P27695,O43913,Q9NTI5,Q7Z460,Q7Z5K2,P53350,Q6UXN9 31 +Bleb 0.7828779666860906 2.431586374137369 0.0150328635463288 0.9999989032772572 0.1071102430768144 4 Q96RD7 1 +Polar microtubule 0.7723067740972784 2.4248183527431837 0.0153160480652592 0.9999991548084516 0.1071102430768144 2 Q96CW5 1 +Filtration diaphragm 0.7675320799761141 2.4021438280112446 0.0162992984772081 0.9999996581300874 0.1118642698681386 2 P46940 1 +Nuclear cyclin dependent protein kinase holoenzyme complex 0.7710126585070405 2.354413116549676 0.0185519800984148 0.999999957167181 0.1217977823852453 5 O75909 1 +Cell leading edge 0.3174869532773337 2.3322252976991047 0.0196888420039083 0.9999999850123018 0.1265112826634108 116 Q9UM54,P31146,O15357,Q9Y217,P31751,P19174,P18085,Q00535,Q12923,Q9Y2A7,Q7L576,Q9UL63,Q9Y5K6,Q9HCM4,Q9UPN3,P15531,P35241,O60610,P31949,P61586,Q00534,Q8WUW1,Q9H2G2,O94832,P50570,Q16513,Q9UQB8,Q9BPX3,Q14155,Q13418,P43034,Q16512,P63167,P22392,P35580,Q13464,P35579,P60953,Q92974,P46940,Q92538,Q9UHB6,Q9Y5X3,Q86TI2,O00401,Q8NCE2 46 +Trna methyltransferase complex 0.7624994560490838 2.2934426986473593 0.021822530760182 0.9999999979184074 0.1354192662241433 6 Q9UJA5,Q96FX7,Q9UBP6 3 +N terminal protein acetyltransferase complex 0.7521870565000346 2.28450900448308 0.0223416340026971 0.9999999987131392 0.1360714285603079 4 Q5VZE5,Q14CX7 2 +Pole plasm 0.759238327546925 2.277638234076623 0.0227481405382317 0.9999999991171358 0.1364888432293902 6 Q9HCE1,Q9Y2V2 2 +Ribose phosphate diphosphokinase complex 0.7450746268656739 2.272027724057395 0.0230848358791448 0.9999999993538892 0.1368429288307245 3 Q14558,P11908 2 +Multimeric ribonuclease p complex 0.7467900865929896 2.258404177500383 0.0239204725231636 0.999999999702426 0.1387638606507618 4 O75818,Q99575,O95707 3 +Nonhomologous end joining complex 0.7413410863910715 2.231974997237574 0.0256166154686083 0.9999999999384452 0.1429959509123038 4 P78527 1 +Juxtaparanode region of axon 0.7338840939533604 2.2178253555851932 0.0265667425829607 0.9999999999745668 0.1449967998804967 3 Q8IXJ6 1 +Centriolar subdistal appendage 0.7247761194029881 2.173481970970459 0.0297440613030932 0.9999999999986848 0.1575913423427046 3 Q14203,Q5SW79 2 +Gamma tubulin complex 0.7208997506522582 2.15454772858904 0.0311972432156748 0.9999999999996616 0.1624408181229966 3 Q96CW5 1 +Annulate lamellae 0.7293451345179867 2.15217921416619 0.0313832420839839 0.9999999999997158 0.1624755275890824 5 O14980,Q9Y5L0 2 +Glycogen granule 0.7193316249419788 2.146877772552757 0.0318030136111464 0.999999999999808 0.1634459437833303 3 P49327 1 +Ribonuclease mrp complex 0.7225085777152827 2.118597762954705 0.0341244749541858 0.9999999999999782 0.1707958615572977 5 O75818,Q99575,O95707 3 +Myosin filament 0.7080216613080164 2.0913827920892833 0.0364937634800077 0.9999999999999976 0.1768093567534066 3 P35579 1 +Cd95 death inducing signaling complex 0.7014925373134365 2.0592065989071444 0.0394744512980747 1.0 0.1858014525486997 3 Q14790,P49327 2 +Axon 0.3008518547338166 2.058729642231095 0.0395201449544533 1.0 0.1858014525486997 131 Q93008,Q13614,P21359,P38935,Q9Y5K6,Q9UBF2,O14965,P27708,P42858,Q9Y496,Q14204,Q9NZ32,Q9H269,P04350,O94832,P53621,Q9NZJ4,O00203,P50570,Q8TEW0,Q8IXJ6,Q96N67,Q96Q89,O60333,Q16512,P78559,O75592,O14617,P27695,P22681,P46940,Q8TAG9,Q7Z460,P46821,Q15334 35 +Transcription factor tfiiic complex 0.7091007669881364 2.0524189288452694 0.0401289664922184 1.0 0.1858014525486997 5 Q12789 1 +Rna polymerase iii transcription regulator complex 0.7091007669881364 2.0524189288452694 0.0401289664922184 1.0 0.1858014525486997 5 Q12789 1 +Ribonuclease p complex 0.7138809359719249 2.036810788030645 0.0416690068087994 1.0 0.1891263941528305 7 O75818,O15091 2 +Phosphorylase kinase complex 0.6920322291853185 2.0360059691053007 0.041749755883627 1.0 0.1891263941528305 2 Q93100 1 +Chromatoid body 0.6940298507462754 2.0223064001131035 0.0431447078563649 1.0 0.1897529384362457 3 Q08J23,Q8NHU6 2 +Escrt i complex 0.6881527902118639 2.0168155242006227 0.0437147682697329 1.0 0.1904568859163909 2 Q99816 1 +Nata complex 0.687555953446723 2.0138599973722666 0.044024234450092 1.0 0.1908418967070976 2 Q9GZZ1 1 +Potassium channel complex 0.6866606982990081 2.0094251376164207 0.0444920665667911 1.0 0.1913013165734546 2 Q99996 1 +Alpha dna polymerase primase complex 0.6891609435652406 1.9752722880833955 0.0482372562983561 1.0 0.2028058822690662 4 P09884,P49642,P25205 3 +Cytosolic large ribosomal subunit 0.7155239132800705 1.9707552550138543 0.0487518769816772 1.0 0.2028058822690662 46 P18621,Q07020,P61353,P46776,P40429,P62424,Q02543,P83731,P42766,Q02878,P46779,P32969,P46778,P27635,P62917,P47914,P62750,P84098,P36578,P62906,P61313,P50914,P62910,P26373,P18124,P61513,P39023,P61254,P62899,Q9Y3U8 30 +Microtubule cytoskeleton 0.2434826383824463 1.9614615312240908 0.0498252082687855 1.0 0.2051892667796351 373 Q3SYG4,Q15398,O75116,O43670,Q00535,Q12873,Q9Y6D5,Q8NI35,Q9UPN3,Q9Y5K8,P50748,Q5VYK3,P42858,P53985,Q00534,O76071,O60271,Q9NR09,P78559,P27695,Q13464,P60953,Q14674,Q92974,Q99996,P46940,Q14152,Q9BTW9,Q86TI2,P36507,P49841,Q99504,Q92547,Q99426,Q9BSJ2,Q9Y5Y2,Q6NUK4,Q5SW79,Q14203,P17612,Q03518,Q13045,Q9Y496,Q14204,Q9NZ32,Q9H8V3,Q5T4S7,Q9P1Y5,O00429,Q8IXJ6,P14635,O43237,Q13315,P31689,Q9BPX3,Q14155,O75592,P63167,Q9BW19,Q6NXR4,Q96GX5,Q7Z5K2,Q13618,Q9Y237,Q13526,Q99661,Q15058,Q14999,Q9BUF5,P62081,Q13885,Q14839,O60610,P63172,Q08J23,P18074,Q99741,P04350,O94967,Q8WWK9,Q9Y3D8,Q9BZH6,Q96P70,Q8WUX9,Q9Y696,Q96Q89,Q9UQB8,O60333,P43034,O95067,P28482,P29372,Q3KQU3,Q15019,Q99986,Q7Z4H7,Q7Z460,Q14166,P53350,P46821,Q66K74,Q99816,Q9UHD1,Q13432,Q13330,Q9P258,Q9Y5K6,O14965,P50570,Q00610,Q96CW5,Q16513,Q9BT25,Q9BVQ7,Q16512,Q14008,P35579,Q99570,Q9H6H4 119 +Condensin complex 0.6992410048693818 1.945845247102324 0.0516733316018922 1.0 0.2062380547634994 8 Q15003,Q15021,Q9NTJ3,Q9BPX3,P42695 5 +Torc1 complex 0.6675619218143709 1.914373250132177 0.0555724809855244 1.0 0.2151652468926717 2 P42345 1 +Tor complex 0.6675619218143709 1.914373250132177 0.0555724809855244 1.0 0.2151652468926717 2 P42345 1 +Scf ubiquitin ligase complex 0.6898761102859318 1.898676780910809 0.0576069862474857 1.0 0.2211522438145003 8 Q9Y3I1,Q13309 2 +Excitatory synapse 0.6752858505030633 1.8837049144941584 0.0596049013110948 1.0 0.2268594411349034 5 Q9UQB8,Q15334 2 +Myosin ii complex 0.6683213695495234 1.8710044098086007 0.0613444697900231 1.0 0.2287164182294691 4 P35579,P35580 2 +Mmxd complex 0.6621552040214704 1.839974844487463 0.0657719305757884 1.0 0.2378379170599263 4 O76071 1 +Rna polymerase iii complex 0.667463105237604 1.822703398685956 0.0683483252789636 1.0 0.2457285027886549 6 Q9NW08,O14802 2 +Photoreceptor connecting cilium 0.6468656716417961 1.7862014950822955 0.0740666391120532 1.0 0.2571048851935641 3 Q15019,Q15555 2 +Neuron projection 0.2503847566090863 1.7340458419773872 0.0829099496701262 1.0 0.2765453141345127 225 P17655,P49841,Q8IZH2,Q93008,Q13614,P21359,Q01968,Q00535,P38935,Q12923,Q9Y6D5,Q9Y5K6,Q14203,Q9UBF2,O14965,P17612,P27708,P42858,P46779,Q9Y496,Q14204,Q9Y296,Q96F07,Q9Y3I1,Q9H269,Q9NZ32,P04350,O94832,P53621,Q9NZJ4,P42345,O00203,P50570,Q9UBB6,Q8TEW0,Q8IXJ6,Q7KZI7,Q96N67,Q96Q89,P62753,Q9UQB8,O60333,Q16512,P78559,O75592,O14617,P27695,Q06787,Q13555,P22681,P60953,P40818,Q99996,P46940,Q8TAG9,Q7Z460,Q9P265,P46821,Q15334,Q9BPU6,Q66K74 61 +Main axon 0.6668762566329205 1.731320614259794 0.0833945967482738 1.0 0.2767600903074583 11 P04350,P78559,Q8TEW0,Q8IXJ6,P46821,Q15334 6 +Transcription factor tfiih holo complex 0.6370582173195866 1.7129023156270584 0.0867305122111559 1.0 0.2847023335627074 4 Q92759,P18074 2 +Smn complex 0.6379686913021108 1.694771441803072 0.0901187869985937 1.0 0.2895305709954821 5 Q8TEQ6,P57678,Q9Y3F4 3 +Dendritic tree 0.282609768358268 1.6837831647373176 0.0922235819506265 1.0 0.2921488295359007 113 P17655,P49841,Q8IZH2,Q13614,P21359,Q00535,Q9Y6D5,Q9Y5K6,P17612,P42858,P46779,Q9Y296,O94832,Q9NZJ4,P42345,Q9UBB6,Q7KZI7,P62753,Q9UQB8,O60333,Q16512,P78559,P27695,Q06787,P60953,P40818,Q99996,Q7Z460,Q9P265,P46821,Q15334,Q9BPU6,Q66K74 33 +Exocyst 0.6394250518418597 1.6801936115019558 0.0929196519208523 1.0 0.2923169401230545 6 Q8TAG9 1 +Ripoptosome 0.6207102357505171 1.6778761358273997 0.0933712821653576 1.0 0.2923169401230545 2 Q14790 1 +Er membrane insertion complex 0.6253731343283638 1.6770978117631477 0.0935233566440132 1.0 0.2923169401230545 3 Q7L5D6,P46379 2 +Proteasome core complex alpha subunit complex 0.6405864286062805 1.6665153114582931 0.0956108211100779 1.0 0.2966554928963376 7 P25787,P25789,P28066,P60900 4 +Nucleolus 0.2309736522662028 1.6499537192998723 0.0989524022133352 1.0 0.3039012759501075 437 Q15648,O43670,O75607,P42696,P51532,P62424,Q12873,Q12923,Q96DE0,Q9GZR7,P78362,Q96JP5,Q7L5D6,O75818,P42766,P22059,P46777,Q08945,Q96P11,P84098,Q9H9T3,Q8IY81,O75691,P62753,P27695,Q06787,P62277,P39023,Q8WTT2,P35251,Q9UIF9,Q14152,Q9Y3Y2,Q8IUF8,Q14527,P04818,Q12789,Q9BYG3,Q96D46,Q9UBP6,Q5TAX3,P46087,Q9Y2L1,Q7L014,Q9UBB9,Q01844,Q5C9Z4,Q5T3I0,P29375,Q96IU4,P78527,Q8IWS0,Q9UHB9,Q16881,P36578,Q99575,Q8IXJ6,Q13315,O95707,P11802,Q9UDY8,Q9BPX3,P33993,Q92522,Q9HB07,Q9Y3U8,Q9UNF1,Q9UID3,Q14684,O00410,Q2NL82,Q9BRT6,Q9UPP1,Q9Y237,Q8IY37,Q13085,P62136,P21359,P54132,Q5SY16,Q6DN90,Q9P2D1,Q9NVU7,Q96GQ7,Q9H0D6,P15880,Q14692,P62081,Q9NUL7,Q13309,P62280,Q08J23,P78316,Q99543,Q9BV44,P62750,P57678,P61247,Q96Q89,Q9GZR2,O60921,P26373,Q99986,Q9H9L3,Q66K74,Q6UXN9,Q99816,Q07020,P09874,P61353,P40429,Q5F1R6,Q9P258,Q9UER7,Q9Y5K6,O14980,O43709,P62851,Q5JTH9,Q14008,P18124,P61254 122 +Cd40 receptor complex 0.6177986203206604 1.6384510690183864 0.1013276333409312 1.0 0.3081054410647888 3 O15111 1 +Death inducing signaling complex 0.6267105743314495 1.6372814740773252 0.1015716700217335 1.0 0.3081054410647888 5 P42574,Q14790,P49327 3 +Apical dendrite 0.6217467683979674 1.6348162028851398 0.1020875830846304 1.0 0.3081054410647888 4 P46821 1 +Copi vesicle coat 0.6413519094078177 1.633510179984472 0.1023617414575071 1.0 0.3081054410647888 9 Q9UBF2,P53618,Q9Y678,P53621 4 +Cul2 ring ubiquitin ligase complex 0.6201851298895097 1.626830642564869 0.1037730716805693 1.0 0.3113192150417081 4 Q92990,Q15370,Q15369 3 +Presynaptic cytosol 0.6225247566187296 1.615855897091873 0.1061254728697154 1.0 0.3169964184541376 5 P42858 1 +Cyclin dependent protein kinase holoenzyme complex 0.6515491469662826 1.6075511837421446 0.1079335109326788 1.0 0.3181682101328292 14 O95067,Q00535,O75909,Q9NYV4,P14635,Q00534 6 +Protein phosphatase type 2a complex 0.6206993631153519 1.6065043302221236 0.1081631442835666 1.0 0.3181682101328292 5 Q15257,P63151 2 +Carboxy terminal domain protein kinase complex 0.6299938283661075 1.5932034276592264 0.1111145625437215 1.0 0.3231925400359947 8 O75909,Q9NYV4 2 +Phagocytic cup 0.6176793305889205 1.591022162921328 0.11160458808643 1.0 0.3231925400359947 5 Q9Y5X3,P50570,P31146 3 +Replisome 0.6395613648628802 1.590319054302532 0.1117629057547797 1.0 0.3231925400359947 11 P35244,P28340 2 +Elongator holoenzyme complex 0.6112272320095429 1.5809533617624445 0.1138887018653926 1.0 0.3265289996520435 4 Q9H9T3,O95163,Q96EB1 3 +Cell tip 0.5998209489704458 1.5711176812488117 0.1161553163202444 1.0 0.3294859405070062 2 P35241 1 +High density lipoprotein particle 0.598627275440164 1.5649968638022416 0.1175836446737443 1.0 0.3307002073131871 2 Q00341 1 +Saga type complex 0.6311263149619214 1.56332011494375 0.1179773193687505 1.0 0.3307002073131871 10 Q9UPT9,Q9Y4A5 2 +Ciliary tip 0.6210428076904561 1.547069385020625 0.1218465153473498 1.0 0.3375930975678866 8 P63167,Q8NCM8,Q9Y496,Q15555,Q9BW83,Q96FJ2 6 +Myosin complex 0.6248720687163891 1.530933246015362 0.1257858915428273 1.0 0.3432590895716916 10 Q9UM54,O43795,O94832,P35580,P35579,Q92614 6 +Cell substrate junction 0.2532582576694128 1.5292912445614393 0.1261922591685236 1.0 0.3433338943143615 185 P36507,P17655,P08708,P46782,Q07020,P61353,Q5VW36,P40429,P62424,P42356,P62701,Q9Y2A7,P62241,Q9HCM4,P15880,P62081,P62269,P35241,P62841,Q02878,Q13045,P32969,P46777,P62280,P62917,Q9UHB9,P17096,P61247,P84098,P36578,P50570,P62906,Q00610,Q96N67,O14976,Q14155,Q13418,Q16512,P22392,P28482,P18124,P22681,P62277,P60953,P61513,P39023,P35579,Q92974,P62899,P46940,Q7Z460,Q9UHB6 52 +Sperm annulus 0.5958208955223944 1.525819604264397 0.1270547969900393 1.0 0.3446456469250766 3 Q15019,Q14141 2 +Translation preinitiation complex 0.6384216782340032 1.5124180909964782 0.1304275354972035 1.0 0.3506449470636985 16 P41567,Q7Z478 2 +Somatodendritic compartment 0.2687257425831303 1.4995903867081235 0.1337205393951435 1.0 0.3573770167905605 146 P17655,P49841,Q8IZH2,Q13614,P21359,Q00535,Q9Y6D5,Q9Y5K6,Q14203,O14965,P17612,P27708,P42858,P46779,Q9Y296,Q9H269,P04350,O94832,Q9NZJ4,P42574,P42345,Q9UBB6,Q8IXJ6,Q7KZI7,P62753,Q9UQB8,O60333,Q16512,P78559,O75592,P27695,Q06787,P60953,P40818,Q99996,Q7Z460,Q9P265,P46821,Q15334,Q9BPU6,Q66K74 41 +Proteasome core complex beta subunit complex 0.5982131196831939 1.4484117001754584 0.1475019445373724 1.0 0.3818193192881697 7 P20618,P49721,P49720 3 +Transferase complex transferring phosphorus containing groups 0.424066726647091 1.446009937716059 0.1481744144951813 1.0 0.3824672921157672 87 Q9UM54,O75909,Q00535,P28340,Q9BUI4,Q9Y4A5,P20248,Q9NYV4,Q14558,Q00534,P78527,P18074,Q07864,O00443,Q8TEW0,Q08AM6,P14635,O14802,P17858,O15111,P49005,O95067,Q9NW08,Q9Y6J9,Q99570,P08237 26 +Rna cap binding complex 0.592032279088403 1.4366310245171288 0.1508228633324864 1.0 0.3849169413499512 6 O60573,Q7L576,Q06787 3 +Origin recognition complex 0.5931065537406277 1.4220072721202153 0.1550241398419167 1.0 0.3921276177962637 7 Q9UBD5 1 +Mcm complex 0.587459106730899 1.413007864177577 0.1576534118148835 1.0 0.3942519789083025 6 P33993,P33991,P33992 3 +Insulin responsive compartment 0.5681886004177773 1.4083316077844446 0.1590329004430497 1.0 0.3958346368170414 2 P51153 1 +Dna polymerase complex 0.6008042963368315 1.4059959438720202 0.1597253292207106 1.0 0.3964688993807227 10 Q07864,P28340 2 +Protein phosphatase type 1 complex 0.571937407995334 1.4027666052300751 0.1606864483143921 1.0 0.3966809868469735 3 P62136 1 +Extrinsic component of endosome membrane 0.5747768975659698 1.3932849344704232 0.1635336445621571 1.0 0.4004364377657145 4 P40818 1 +Cytoplasmic dynein complex 0.5967333788523543 1.367665753889335 0.1714167241603381 1.0 0.4152501392761132 11 P63167,Q8NCM8,Q9UJW0,Q14204,O43237,P63172,Q96FJ2 7 +Polysomal ribosome 0.6285095138805331 1.3652214031416476 0.1721834732842417 1.0 0.4159952714547281 27 Q07020,P62266,P84098,P62854,P83731,Q6PKG0,Q02878,P62906,P62899,P62424,Q9Y3U8,P62917,P62910,Q02543 14 +Glial cell projection 0.567219689287925 1.3309240853918844 0.1832139912385093 1.0 0.4356742153860616 5 Q8IXJ6,Q06787 2 +Ribonucleoprotein complex 0.2225789245508211 1.3289450181224898 0.1838661100382133 1.0 0.4360803552215216 433 P41567,Q9Y383,P67809,P62847,P46776,O15091,P38935,Q8IYB3,Q8IXT5,Q9HAV4,O75818,P42766,P62917,P84098,P62854,P61313,Q7Z478,P62753,Q92616,P50914,P62910,Q7L2J0,P39023,P62899,P46940,Q14152,P18621,P08708,P62314,Q12789,O76094,Q9UBB9,P46778,P27635,O43290,P78527,P36578,Q99575,O60231,P62266,Q9Y3U8,Q2NL82,Q5VTL8,P62701,Q96BP3,Q96HR8,P15880,P62081,P62269,P62841,P83731,Q02878,P62280,P78316,P47914,P62750,P57678,P61247,Q9Y312,P26373,P61513,Q6PKG0,Q07020,P61353,P40429,Q4G0J3,P62241,Q02543,O14980,P07814,P26196,P46779,P60866,P62851,P62906,Q69YN2,Q92917,Q9HD33,Q9UNY4,P18124,P61254,P82675,Q9HAU5 83 +Pericentric heterochromatin 0.581446073319819 1.3233719228454923 0.1857117241783981 1.0 0.438163599233408 9 P26358 1 +Cytosolic small ribosomal subunit 0.6222297334044007 1.3169754826740063 0.1878468428380646 1.0 0.4409047658323485 33 P15880,P08708,P62266,P62847,P62081,P62269,P62841,P61247,P62854,P60866,P62851,Q7Z478,P62701,P62280,P62753,P62241 16 +Unconventional myosin complex 0.5591264124709922 1.3124099524093524 0.189381850657698 1.0 0.4422242686792229 4 Q9UM54,P60660 2 +Trapp complex 0.5581021978486146 1.307115215214432 0.1911735845667155 1.0 0.4452526159831472 4 Q9Y296 1 +Nuclear replication fork 0.5986448285118622 1.3028106163432642 0.192639425421889 1.0 0.4475162036723884 16 Q9H4L7,P35244,P28340 3 +Vesicle tethering complex 0.6100508995069027 1.2979841945343484 0.1942927662394995 1.0 0.4502026757365386 22 Q9H269,Q14746,Q96KP1,Q7Z392,P60953,Q96JB2,Q8TAG9,Q9UID3,Q9Y296 9 +Ccr4 not core complex 0.5490557687687538 1.260351180575739 0.2075427045715931 1.0 0.4724464581453854 4 A5YKK6,Q9UIV1 2 +Cul4 ring e3 ubiquitin ligase complex 0.5675680741204667 1.251339220514908 0.2108107419260647 1.0 0.4760307576539158 9 Q13620,Q5TAQ9,Q9BW61,Q92990 4 +Chromosome centromeric region 0.2951368558384455 1.2400561565437938 0.2149546239953137 1.0 0.4807708916177839 100 O43670,Q6P1K2,P26358,Q9P258,Q9UER7,P42695,O14980,Q15021,P50748,Q8IWS0,Q29RF7,Q8WUX9,P14635,O43237,Q9NTJ3,Q9BPX3,Q14008,Q9NTI5,Q7Z460,Q7Z5K2,P53350 21 +Outer kinetochore 0.5614729157197539 1.238622621683076 0.2154852865007412 1.0 0.4807708916177839 8 P14635 1 +Supramolecular complex 0.2222149558139126 1.238051394530136 0.2156970047395241 1.0 0.4807708916177839 386 Q9UM54,P67809,O75116,O43670,Q6P1K2,Q00535,Q9Y6D5,Q9UPN3,P50748,Q92499,Q7KZI7,P62753,P78559,Q06787,Q13464,Q04637,P60953,Q92974,P46940,Q14152,Q9Y3Y2,Q9Y2V2,Q9BTW9,Q86TI2,P36507,O75880,Q8IZH2,Q99426,Q9BSJ2,Q6NUK4,Q92600,Q5SW79,Q14203,Q5TAX3,P25787,Q9Y496,Q14204,Q92674,Q8IWS0,Q9HCE1,Q86TB9,Q8NHU6,Q9P1Y5,O00429,Q8IXJ6,P14635,O43237,Q13418,P63167,P35580,Q9BW19,Q9H900,Q96C86,O00401,Q13618,P42694,O43795,P31146,A5YKK6,Q08209,P62701,Q9Y2A7,Q2NKX8,Q99661,Q15058,Q9BUF5,Q13885,Q02878,Q9NUL7,P63172,Q9Y520,P04350,O94967,Q8WUX9,Q9NZQ3,Q96Q89,Q9UQB8,Q13501,P62942,O60333,P29372,Q6PKG0,Q7Z460,P53350,P46821,Q66K74,Q9UIV1,Q9P258,Q9Y5K6,O14965,O14980,P26196,P46779,Q96F86,P49917,P50570,Q00610,Q96CW5,Q9BT25,Q14258,Q16512,Q14008,P35579,Q9H6H4,Q9H6S0,Q9HAU5 106 +Centriole 0.6013996437352334 1.222174623978442 0.2216415979286794 1.0 0.4879574764363674 26 O14965,P27695,Q13464,P42858,Q96CW5,Q9Y496,Q8IXJ6,Q9Y5Y2,P53350,Q9BPX3,Q5SW79 11 +Proteasome core complex 0.5775725782545593 1.220178930687292 0.2223970521239036 1.0 0.4879574764363674 14 P49721,P28072,P60900,P20618,P25787,P28066,P49720,P25789 8 +Kinetochore microtubule 0.5474234138252891 1.2060054416709591 0.2278153922434129 1.0 0.4926032109129645 6 Q8WUX9,P50748 2 +Tubular endosome 0.5368198730445324 1.197140976946248 0.2312516106579658 1.0 0.4976578604658362 4 Q9Y5X3,O75436 2 +Polymeric cytoskeletal fiber 0.2387972365271791 1.1934153368156346 0.2327067514254293 1.0 0.4984215526984372 187 Q9UM54,P36507,O43795,P31146,O43670,Q99426,Q00535,Q9BSJ2,Q9Y2A7,Q9P258,Q6NUK4,Q9Y6D5,Q5SW79,Q99661,Q14203,Q9Y5K6,O14965,Q15058,Q9UPN3,Q9BUF5,P50748,Q13885,Q9Y496,Q14204,P63172,P04350,O94967,P50570,Q9P1Y5,Q8WUX9,O00429,Q00610,Q8IXJ6,Q7KZI7,Q9NZQ3,Q96Q89,O43237,Q96CW5,Q9UQB8,Q9BT25,O60333,P46821,P78559,P63167,Q16512,Q14008,Q9BW19,P29372,Q92974,Q9H6H4,P46940,Q7Z460,Q14152,Q86TI2,P53350,Q9BTW9,O00401,Q13618,Q66K74 59 +Endoribonuclease complex 0.5790246697717171 1.186554475367671 0.2354034018905031 1.0 0.5008565563083424 17 O75569,O75818,O15091 3 +Golgi apparatus 0.2184069160465597 1.1459377330006697 0.2518209170835619 1.0 0.5220818097888034 301 Q9UM54,P36507,P17655,P21399,O14681,O15357,Q9Y3E0,Q6P1K2,Q01968,P53618,P49327,Q13535,Q13190,P57737,Q9Y4A5,Q9Y6D5,Q9Y314,Q9UBF2,Q86VP6,Q14746,P52701,P20645,Q9UPN3,Q14CX7,Q14999,Q5VYK3,P42858,Q6XZF7,P22059,Q6NTF9,Q9Y296,O95070,O43290,Q9Y678,Q9Y6B6,O43505,P53621,Q7Z6Z7,P42345,O00203,P50570,O00443,P49407,Q92614,Q00610,Q08AM6,O14976,Q9UQB8,Q9NR09,O96017,O75592,O14617,Q13464,P28482,P22681,P60953,Q96JB2,P50851,Q9HC07,Q92974,Q15042,Q99996,Q99986,Q7Z460,Q92538,Q7Z5K2,Q5JSH3,Q9UID3,Q15334,Q99805,Q6P6C2 71 +Rdna heterochromatin 0.5258180169471849 1.140401690224213 0.2541189890355912 1.0 0.5256433882790997 4 Q9UIF9 1 +Scar complex 0.5297960256161549 1.115126489832927 0.2647962213656032 1.0 0.5393771595745549 6 Q96F07,Q9Y2A7,Q8WUW1 3 +Anchoring junction 0.2204855807669045 1.1040515655720606 0.2695707698002341 1.0 0.5439445822695147 261 P36507,P17655,P08708,P46782,Q07020,P61353,Q5VW36,P40429,P62424,P42356,P62701,Q9Y2A7,P62241,Q9Y5K6,Q9HCM4,P15880,Q8NI35,P62081,P62269,P35241,P62841,Q02878,Q13045,Q6XZF7,P32969,P46777,P31949,Q96RD7,P62280,P62917,Q9UHB9,P17096,Q9H8V3,P61247,P84098,P36578,P50570,Q9P1Y5,P55196,P62906,Q8TEW0,Q8IXJ6,Q96N67,Q00610,Q16513,O14976,P11802,Q9Y613,Q9UQB8,Q14155,Q13418,Q16512,P22392,P28482,P18124,P22681,P62277,P60953,P61513,P39023,P35579,Q92974,P62899,P46940,Q7Z460,Q9UHB6,Q9BTW9 67 +Eukaryotic translation initiation factor 2b complex 0.5272848820757712 1.1022146183884898 0.2703683781617072 1.0 0.5443416680322373 6 P49770,Q9NR50,Q14232,Q13144 4 +Filopodium tip 0.5204293263370088 1.089465296596644 0.2759487503740758 1.0 0.54947157766794 5 Q7L576,Q06787 2 +Dna repair complex 0.5640354561680255 1.0836254202596574 0.2785309151755295 1.0 0.5533969498882231 19 P49917,P52701,P20585,P28340,Q13315,P78527,P54277 7 +Microtubule plus end 0.5269731906032928 1.0417078411452718 0.2975471525123772 1.0 0.5809042277357256 9 Q14203,Q14008,Q99661,Q7Z460 4 +Microtubule end 0.5336675827653765 1.0404169943361177 0.2981462095994618 1.0 0.5809042277357256 11 Q14203,Q14008,Q9P1Y5,Q7Z460,Q99661 5 +Filamentous actin 0.5100497196385448 0.974148291481558 0.329982914695798 1.0 0.6324616404278294 8 Q9Y2A7,Q9Y5K6 2 +F actin capping protein complex 0.5021592643174557 0.9737723642697168 0.3301695776909494 1.0 0.6324616404278294 6 Q9BPX3 1 +Copi coated vesicle membrane 0.5202974775596816 0.9719722871444832 0.3310643355645499 1.0 0.6327938565854055 11 Q9UBF2,P53618,P53621 3 +Calcium channel complex 0.5092785530162879 0.970228989076108 0.3319323639837981 1.0 0.63282994155577 8 Q15257,P62942,Q9NWR8 3 +Dna replication preinitiation complex 0.515889958130232 0.9669406772972804 0.3335736902696573 1.0 0.63282994155577 10 Q9UBD5,P33993,P33991,P33992 4 +Nucleocytoplasmic transport complex 0.5076531248514576 0.9432059413133652 0.3455755750293139 1.0 0.6509178190780839 9 Q9HAV4 1 +Large ribosomal subunit 0.4693937448086172 0.9345149150893995 0.3500383459120288 1.0 0.6559029422228229 71 P18621,Q07020,P61353,P46776,P40429,P62424,Q02543,P83731,P42766,Q02878,P46779,P32969,P46778,P27635,P62917,P47914,P62750,P84098,P36578,P62906,P61313,P50914,P62910,Q9HD33,P26373,P18124,P61513,P39023,P61254,P62899,Q9Y3U8 31 +Core mediator complex 0.4979754987544612 0.932422887836108 0.3511180209470961 1.0 0.6559029422228229 7 Q15648,Q9ULK4,Q9Y2X0 3 +Postsynaptic density intracellular component 0.4833631081369274 0.9235330978330148 0.355729460335678 1.0 0.6617882773390642 4 Q9UQB8 1 +Postsynaptic specialization intracellular component 0.4833631081369274 0.9235330978330148 0.355729460335678 1.0 0.6617882773390642 4 Q9UQB8 1 +Magnesium dependent protein serine threonine phosphatase complex 0.5050758412748588 0.9121407740513828 0.3616946165926289 1.0 0.6660474037254508 10 Q15257,Q14738,Q8TF05,P63151 4 +Cytoplasmic microtubule 0.5341053948462122 0.9059492924651076 0.3649626923013054 1.0 0.6707022296652793 21 P29372,Q9Y6D5,O15344,Q9H6H4,Q9BSJ2,Q14204,Q7Z460,P63172,Q6NUK4,Q99661,P43034 11 +Trna splicing ligase complex 0.4835960131575889 0.8801392308365896 0.3787838889393564 1.0 0.683646147739882 6 Q8NCA5,Q92499 2 +Dendritic shaft 0.470821893834909 0.8381950124311355 0.4019211877636199 1.0 0.7195296439939114 5 P78559 1 +Signal recognition particle 0.4749210914056376 0.8368965944071343 0.4026506948177848 1.0 0.7195296439939114 6 O76094,Q9UHB9 2 +Rnai effector complex 0.4798903548814126 0.8226795516326272 0.4106902466679845 1.0 0.7281513962449979 8 Q9HAV4 1 +Post mrna release spliceosomal complex 0.4737115883322856 0.8111838415186218 0.4172601035559244 1.0 0.7354818167736723 7 Q9UBB9 1 +Aminoacyl trna synthetase multienzyme complex 0.4877319107895231 0.8082649316851361 0.4189380856480866 1.0 0.7370056419362456 11 P47897,Q9P2J5,P41252,P07814 4 +Small ribosomal subunit 0.5237498562607468 0.8008489631074864 0.4232190893398018 1.0 0.7416566633304843 46 P15880,P08708,P62266,P62847,P62081,P62269,P62841,P61247,P62854,P60866,P62851,Q7Z478,P82675,P62701,P62280,P62753,P62241 17 +Spindle 0.2307333418818453 0.791864338773297 0.4284397824260404 1.0 0.7479122213448798 158 Q15398,Q9Y237,Q13432,O43670,Q92547,O15344,Q9BSJ2,Q9Y5Y2,Q9P258,O00139,Q5SW79,Q99661,Q14203,O14965,P98170,Q15058,P50748,O60610,Q9Y496,P63172,Q08J23,Q15555,P18074,Q99741,Q9H8V3,Q8WWK9,Q8WUX9,Q00610,Q8IXJ6,Q96Q89,Q96CW5,P14635,O76071,Q13315,Q9BT25,Q9BPX3,Q9BVQ7,Q9NR09,Q14155,P43034,P63167,Q14008,Q9BW19,P28482,Q3KQU3,P29372,P60953,Q15019,P35579,Q14674,Q92974,Q99986,Q7Z4H7,Q7Z460,Q14166,Q7Z5K2,P53350,Q13618,Q66K74 59 +Pseudopodium 0.4699955956867263 0.7558417098031363 0.4497441058416611 1.0 0.7717199997964868 9 P49407,P28482 2 +Ruffle 0.4919191791385508 0.736906529587149 0.4611791929600206 1.0 0.7883407281937626 57 Q9UM54,P31751,P19174,Q9Y2A7,Q7L576,Q9UL63,Q9Y5K6,Q9HCM4,Q9UPN3,P15531,O60610,P61586,P31949,Q00534,P50570,Q9UQB8,Q9BPX3,Q14155,Q16512,P22392,P63167,Q13464,P35579,Q92974,Q8NCE2,P46940,Q9UHB6,Q9Y5X3,Q9Y217 29 +Chromatin silencing complex 0.4591380572018477 0.7213329143556716 0.4707047107484134 1.0 0.79711863165993 8 Q8IXJ6,Q9UIF9,O43159 3 +Cell body 0.233060279179893 0.6938874824894453 0.4877527742222793 1.0 0.8157425832260818 103 P17655,Q8IZH2,Q00535,Q12923,Q14203,O14965,P27708,P46779,Q9H269,P04350,O94832,P42574,Q9UBB6,Q8IXJ6,P62753,Q9UQB8,P78559,O75592,Q06787,P60953,Q99996,Q7Z460,Q9P265,P46821,Q9BPU6,Q66K74 26 +Polysome 0.5000981563395697 0.6897501461236717 0.4903513248284781 1.0 0.817321060981767 49 Q07020,P62424,P62701,Q02543,P83731,Q02878,P62917,P84098,P62854,P62906,Q9Y295,P62753,Q92616,P62910,P20290,Q06787,P62266,Q6PKG0,P62899,Q9Y3U8,Q9HAU5 21 +Contractile ring 0.4390846290930519 0.6836933188101298 0.4941688432669768 1.0 0.8184953784275705 5 Q96Q89 1 +Chromosome 0.1974711221075985 0.6782829820472108 0.4975922867193287 1.0 0.8226617003060436 479 O43670,P42696,P35244,P46063,P51532,Q6P1K2,Q12873,Q13535,P26358,Q9UBD5,Q96FZ2,P42695,P78362,Q9NRZ9,P50748,Q14241,Q7L5D6,Q68E01,P40763,Q08945,Q92908,Q96QE3,Q07864,P49407,Q9H4L7,Q8IY81,Q15003,P27695,Q06787,P35251,Q9UIF9,P85037,Q7Z7L1,O75569,P17655,P68400,Q13523,Q92547,Q9BY42,Q92905,P42771,Q9BYG3,P28340,Q9Y3Z3,Q9Y4A5,Q6IBW4,P33992,Q14203,Q69YH5,Q15021,Q96L91,Q9UBB9,Q92674,P78527,Q8IWS0,P16402,Q8IXJ6,Q15185,P19784,P14635,O43237,O14929,Q13315,P11802,O14744,Q9BPX3,Q96SB4,P33993,Q15047,P49005,O96017,Q12830,P63167,O43913,O14646,Q9NTI5,Q6NXR4,Q92522,Q9H900,Q7Z5K2,Q9Y5B9,Q14684,Q7LBC6,Q9BRT6,Q9Y237,P62136,P54132,Q2NKX8,Q96GQ7,Q99661,Q9GZS3,P52701,Q15554,P25440,Q14839,P17096,Q29RF7,Q8WUX9,Q9NTJ3,O60921,O75182,P09429,Q9UGU5,Q7Z460,P53350,Q6UXN9,P09874,Q9P258,Q9UER7,Q9Y5V3,P57081,O14980,Q6PGP7,Q86TU7,Q8NB78,P49917,P50747,Q16512,Q14008,Q8IWI9,Q8TEX9 121 +Kinesin complex 0.4721300695096887 0.6581158276138608 0.5104637061821242 1.0 0.8303054179551248 16 Q15058,Q9BW19,O60333,Q96Q89,Q9Y496,Q99661,P43034 7 +Cytoplasmic ubiquitin ligase complex 0.4420805843537377 0.6404713042168199 0.5218662391722404 1.0 0.841300378452046 8 Q9NT62 1 +Copi coated vesicle 0.4557468104097718 0.6381521422219392 0.5233746470160086 1.0 0.8415324078888201 12 Q9UBF2,P53618,P53621 3 +Perinuclear region of cytoplasm 0.2127665346871505 0.6373945820772912 0.5238678565665502 1.0 0.8415324078888201 194 Q9UM54,O75569,P17655,P36507,O43795,Q9UIQ6,Q9H6S0,Q15436,O00299,P84085,Q9Y217,Q92905,Q13614,O95071,Q7L576,Q9UII4,Q9Y6D5,Q9Y5K6,O14965,Q8NI35,P20645,P17612,Q14999,O43709,P42858,P22059,Q6NTF9,Q96F07,Q9H2G2,Q9H4M9,Q96QK1,P30307,P50570,O00429,Q8IXJ6,Q9Y696,Q96Q89,O95248,P62753,Q16513,O14976,Q14240,O60271,Q9UDY8,P31689,P43034,O75821,O75592,P27695,Q06787,P22681,O15027,Q9H223,Q8TAG9,Q5VIR6,Q5T447,Q5JSH3,Q27J81,Q9BZF3,P46821,Q9Y5X3,Q8NCE2,Q66K74,Q9HAU5 64 +Ccr4 not complex 0.431497624099261 0.6276959215588407 0.5302031576111359 1.0 0.8486997540559879 6 A5YKK6,Q9UIV1 2 +Perinuclear endoplasmic reticulum 0.4308358980957105 0.6246274323409561 0.5322156108909679 1.0 0.8489213793436918 6 P22059,Q9BZF3 2 +Escrt complex 0.4230504018840386 0.6086364041295377 0.5427654690040606 1.0 0.8581946159121796 5 Q8WUX9 1 +Ruffle membrane 0.4807314944375268 0.589783935055442 0.5553355143818963 1.0 0.8704740069723149 27 Q9UM54,Q9HCM4,Q16512,P63167,Q9UPN3,P15531,P50570,O60610,Q13153,P31751,Q92974,P19174,P18085,P61586,Q9Y217 15 +Supramolecular polymer 0.2039564290992506 0.5790202302968712 0.5625755228456144 1.0 0.8748562388986035 232 Q9UM54,P36507,O75880,O43795,P31146,O43670,Q08209,Q99426,Q00535,Q9BSJ2,Q9Y2A7,Q9P258,Q6NUK4,Q9Y6D5,Q5SW79,Q99661,Q14203,Q9Y5K6,O14965,Q15058,Q9UPN3,Q9BUF5,P50748,Q9Y496,Q14204,P04350,O94967,P50570,Q9P1Y5,Q8WUX9,O00429,Q00610,Q8IXJ6,Q7KZI7,Q9NZQ3,Q96Q89,O43237,Q96CW5,Q9UQB8,Q13501,Q9BT25,P62942,Q13418,O60333,P78559,P63167,P46821,P35580,Q9BW19,P29372,Q16512,Q14008,P35579,Q92974,Q9H6H4,P46940,Q7Z460,Q14152,Q86TI2,P53350,Q9BTW9,O00401,Q13618,Q66K74 64 +Transcription elongation factor complex 0.4729157430341641 0.5760146587119849 0.5646052735064211 1.0 0.8748562388986035 24 Q9H3P2,Q08945,Q7KZ85,P18615,Q14241,Q9Y5B9,Q8IXH7,O75909,Q9NYV4,Q15369,Q14004,Q9UNY4,Q9GZS3 13 +Protein kinase complex 0.4837150305557395 0.570666219361188 0.5682259215448389 1.0 0.8764308054502744 34 Q96T76,O95067,P18074,Q93100,P20248,Q8TEW0,O75909,Q00535,Q9NYV4,P14635,Q00534,P11802,Q14004,Q92759,P78527,O15111 16 +Amphisome 0.4102329859033093 0.5703849526178432 0.5684166331576841 1.0 0.8764308054502744 4 Q8WUX9 1 +Ciliary plasm 0.4609356318141614 0.5698058358983028 0.5688093969147476 1.0 0.8764308054502744 19 P04350,P17612,Q9BZH6,Q15019,O95352,Q9P1Y5,Q99570,Q9Y6D5 8 +Ficolin 1 rich granule 0.3305014557952915 0.5573873165685397 0.5772628293569617 1.0 0.8879458801314216 88 P04075,O95352,P53618,Q15008,O00487,P20839,Q86VP6,P13639,P06737,P61160,P25787,P20618,P14174,P53396,O60610,P61586,P63172,P35573,P67870,Q14004,Q9NZ32,Q5T4S7,Q7Z6Z7,O94973,Q9UNP9,P09972,P46976,O43242,Q13200,P06744,P17858,P28066,P18669,P22392,P63167,P09429,P28482,P42785,Q5T9A4 39 +Sperm head 0.401492537313444 0.5515415744871699 0.581262475117966 1.0 0.8925827160286055 3 P08238,P04075 2 +Hulc complex 0.3936138466129443 0.5371753567576105 0.591146491899762 1.0 0.9001323053129149 2 O75150 1 +Dynein complex 0.4347993719565661 0.528400750733616 0.597221216565123 1.0 0.9078564131006734 13 Q14203,P63167,Q8NCM8,Q9UJW0,Q14204,O43237,P63172,Q96FJ2 8 +Swr1 complex 0.4123913717676447 0.5067210916063769 0.6123505294033955 1.0 0.9245426638486856 8 Q9Y4A5 1 +Mediator complex 0.4258320479266299 0.5034730139537041 0.6146317488235893 1.0 0.924694702669335 12 Q15648,Q9ULK4,O60244,Q9Y2X0,Q00534 5 +Nuclear chromosome 0.2988571250975215 0.500117338782201 0.6169924580424069 1.0 0.924694702669335 92 O60921,O75182,O43913,Q07864,Q15021,O14646,Q92547,Q96L91,P35244,Q9H4L7,Q7Z5K2,P28340,Q9UBD5,Q9Y4A5,P49005 15 +Ubiquitin conjugating enzyme complex 0.3938489101224157 0.49792570983293 0.6185364053687947 1.0 0.9247425466404752 4 Q13404,Q9UNE7,O75150 3 +Protein acetyltransferase complex 0.4580030554252161 0.4862257571307204 0.6268071112534837 1.0 0.93419294473191 27 Q9UPT9,Q14CX7,Q5VZE5,Q96L91,Q9Y4A5 5 +Postsynaptic cytosol 0.3987103704068352 0.4815312679218222 0.6301389623976883 1.0 0.93419294473191 6 P42858 1 +Gemini of coiled bodies 0.3943270979164355 0.4811099835166732 0.6304383329230872 1.0 0.93419294473191 5 Q8TEQ6,P57678 2 +Copii vesicle coat 0.4170382020420893 0.4802575904179172 0.6310442408122836 1.0 0.93419294473191 11 P53992,Q15436,P55735,O95486,Q9Y6B6 5 +Transcription factor tfiid complex 0.408977508592756 0.4761754030635091 0.6339494214323631 1.0 0.9355661848358072 9 Q9Y6J9 1 +Synaptonemal structure 0.4029899894434296 0.4666454574045693 0.6407535585226931 1.0 0.9406603550798844 8 Q7Z5K2,P53350 2 +Terminal bouton 0.3938976101354259 0.4612290287303588 0.6446342970879078 1.0 0.9435196658507988 6 O14617,P27708 2 +Photoreceptor outer segment 0.3928929814191051 0.4570333379272482 0.6476470834313481 1.0 0.9448764212380056 6 Q01968 1 +Intrinsic component of peroxisomal membrane 0.3870967741935357 0.4507003864198816 0.6522055038157277 1.0 0.946655952551323 5 O43808,O14975,O96011,P56589 4 +Preribosome small subunit precursor 0.4097017943718287 0.4495342246826839 0.6530463248836389 1.0 0.946655952551323 11 Q2NL82,Q13895,Q8IY81,O75691,Q14684,P78316 6 +Centriolar satellite 0.4489092728652489 0.4469571107863027 0.6549060272649525 1.0 0.9478352407380942 27 Q3SYG4,Q15398,Q8NI35,Q03518,Q12873,P53350,O60271,Q9Y5K6 8 +Multivesicular body 0.3979052518664465 0.4454983639308609 0.655959641864861 1.0 0.9478459896803256 8 Q5VYK3,Q8WUX9 2 +Aggresome 0.3995087313677975 0.4368045966864247 0.6622530650985037 1.0 0.952382979332134 9 Q13501,P13639,P28340 3 +Axon cytoplasm 0.4361878672400891 0.4237182948530075 0.6717712712210593 1.0 0.9644456463243756 23 P78559,Q9NZ32,O14617,P27695,Q9Y496,Q14204,O60333 7 +Inclusion body 0.4425907482821533 0.4085387305155459 0.6828782020374018 1.0 0.973081122886904 29 P27695,P42858,P28340,P35573,Q9Y3I1 5 +Perinucleolar compartment 0.367462686567173 0.4067874558228254 0.6841641007494017 1.0 0.973081122886904 3 P58107,Q92879 2 +Arp2 3 protein complex 0.3797430534807248 0.4035409109980649 0.6865503447275563 1.0 0.9734187986278028 6 P61160,P61158,Q92747,P59998,O15145 5 +Early phagosome 0.3613846612951345 0.4008273078295074 0.6885472721200976 1.0 0.9744218604207948 2 O60493 1 +Pronucleus 0.3776747621430919 0.3953802392862351 0.6925622903255637 1.0 0.9773542601790666 6 O14965 1 +Endosome 0.1984823190841817 0.3791343940059818 0.7045880668047797 1.0 0.9862345879263348 196 Q7Z3U7,Q7Z3T8,P31751,Q01968,Q9P2R3,O75165,Q9P258,Q9Y6D5,P20645,Q5VYK3,P42858,Q9UH99,Q9H269,O94832,P50570,Q8WUX9,Q00610,Q08AM6,O43237,Q13501,Q9NR09,Q16512,O60826,O14617,P27695,P09429,P28482,P40818,Q9HC07,Q9H223,Q99570,Q5JSH3,Q9BZF3,Q9UID3,Q15334,Q99805,Q2M389,Q99816 38 +P body 0.4331699318924754 0.3463399426464426 0.7290872539983373 1.0 1.0 35 Q9HCE1,Q9UIV1,Q86TB9,Q96C86,P25787,Q8IZH2,A5YKK6,P26196,Q9Y2V2,Q13501 10 +X chromosome 0.35052070142238 0.3252911941936156 0.744960694809121 1.0 1.0 4 O75182 1 +Lateral element 0.3502538071065905 0.3243292702250662 0.74568876188574 1.0 1.0 4 P38398,Q9NQS7,P54132 3 +Manchette 0.3453731343283619 0.322695142642835 0.7469261311278907 1.0 1.0 3 Q96SI9,P62826 2 +Condensed chromosome 0.201299736372774 0.321929089713456 0.7475064149550907 1.0 1.0 116 O60921,P49917,P09429,O14980,Q15021,P50748,Q92547,Q8WUX9,Q6P1K2,Q7Z460,P14635,O43237,Q7Z5K2,P53350,Q9BPX3,Q8IWS0,P42695 17 +Platelet dense tubular network 0.3447761194029894 0.3205480878441795 0.7485528829595955 1.0 1.0 3 Q9H4M9,Q14571 2 +Platelet dense tubular network membrane 0.3447761194029894 0.3205480878441795 0.7485528829595955 1.0 1.0 3 Q9H4M9,Q14571 2 +Actin cytoskeleton 0.2022456449542082 0.3101015965597267 0.7564836981936007 1.0 1.0 142 Q9UM54,O43795,P17655,P31146,Q92547,O75607,A1X283,Q9Y2A7,Q9Y5K6,Q9UPN3,P50748,P35241,Q13045,Q9NZ32,O94832,Q92614,Q7KZI7,P47755,Q9Y613,Q9UQB8,Q9BPX3,Q13418,Q16512,P63167,P27695,P35580,P35579,P46940,Q9UHB6,Q15334,O00401 31 +Early endosome 0.2624937981945712 0.2951520507714014 0.7678777290398631 1.0 1.0 94 Q7Z3U7,P36507,O43795,Q7Z3T8,P31146,Q13614,P31751,Q01968,O75165,Q9P2R3,Q9P258,Q5VYK3,P42858,O75436,Q8NB49,Q9H269,Q9H4M9,Q92544,O94832,Q96T51,Q08AM6,P27695,Q9BW19,P28482,P40818,Q9HC07,Q9H223,Q9BZF3,Q9Y5X3,Q15334,Q99816 31 +Nurf complex 0.3487206053275846 0.2892471817609439 0.7723922283109195 1.0 1.0 6 Q9UGU5 1 +Phosphatase complex 0.3851517623970659 0.2870543418731091 0.7740707114448255 1.0 1.0 17 Q15257,Q08209,Q8TF05,Q14738,P63151,Q6UXN9 6 +Microtubule associated complex 0.4149054193516767 0.286461745063144 0.7745244893116525 1.0 1.0 51 O15344,O00139,Q99661,Q14203,O14965,Q15058,Q9Y496,Q14204,P63172,Q9NZ32,Q96P70,Q96Q89,O43237,Q9BT25,O60333,P43034,P78559,P63167,Q9BW19,P29372,Q7Z4H7,P46821,Q66K74 23 +Aster 0.3325373134328419 0.2781123003238172 0.780926153787366 1.0 1.0 3 Q15691,P43034 2 +Cullin ring ubiquitin ligase complex 0.4128762631144692 0.2747452764223133 0.7835119436371645 1.0 1.0 34 Q86VP6,Q9NXV2,Q14999,Q13616,P61962,Q9UJX5,Q92990,Q13309,Q9H1A4,Q5TAQ9,Q15370,Q15369,Q13620,Q96K76,Q9BW61,Q13618,Q9Y3I1 17 +Golgi membrane 0.1988813101897713 0.269242113651996 0.787743374367037 1.0 1.0 131 Q9Y3E0,P53618,Q9Y314,Q9Y6D5,Q9UBF2,Q14746,Q6NTF9,Q9Y296,O95070,Q9Y678,O43505,P53621,Q7Z6Z7,P42345,P49407,Q92614,Q08AM6,O14617,Q96JB2,Q9HC07,Q92538,Q15334 22 +M band 0.3295522388059744 0.2682335683382516 0.7885195376254837 1.0 1.0 3 P04075,Q01082 2 +Cytoplasmic side of endoplasmic reticulum membrane 0.3433970469456882 0.2589455428561074 0.7956772581204881 1.0 1.0 7 P62854 1 +Mitotic spindle microtubule 0.3426853317989814 0.2566838476521722 0.797422841582907 1.0 1.0 7 Q9BT25,Q00610 2 +Sin3 complex 0.3372204726335545 0.2396849254411865 0.8105745221036704 1.0 1.0 7 O75182 1 +Neuron projection terminus 0.3582677773042758 0.2209901845061353 0.8251000756815285 1.0 1.0 15 O14617,Q06787,P27708,Q9UQB8,Q15334 5 +Replication fork 0.3971797710030545 0.2209410683095012 0.8251383196015514 1.0 1.0 35 P35244,P35251,Q9H4L7,P28340,P26358 5 +Ptw pp1 phosphatase complex 0.3263661110650636 0.2189195100250886 0.826712748277765 1.0 1.0 6 Q6UXN9,P62136 2 +Ino80 type complex 0.3405093727812018 0.2168181809118971 0.8283500426570853 1.0 1.0 10 Q9Y4A5 1 +Cytosolic region 0.3328728227746774 0.2156657148612483 0.8292483278654881 1.0 1.0 8 P42858 1 +9plus0 non motile cilium 0.3356804506375193 0.2132153457054137 0.8311589993201487 1.0 1.0 9 Q15019,Q01968,Q15555,P46821,Q96FJ2 5 +Pml body 0.3835906328253423 0.2023637405951747 0.8396323727656114 1.0 1.0 29 O96017,O75925,Q86TB9,P42345,Q92547,Q13535,Q13501,Q9UER7,Q9UKL3 9 +Transcription regulator complex 0.2962803328790404 0.2013146939796438 0.8404525136321994 1.0 1.0 85 Q15648,P68400,P09874,Q99504,Q6P1K2,Q12873,Q12789,Q92759,Q9Y4A5,Q8TEQ6,Q9ULK4,Q14839,Q8N3C0,P40763,P78527,P18074,Q92908,P17096,O60244,P11802,P09429,P51858,P27695,Q9Y6J9,Q9Y2X0,Q8IUF8,Q8WUA4 27 +B wich complex 0.3217502058312252 0.1951887210370641 0.8452452085521558 1.0 1.0 7 Q9NY93,Q9UIG0,Q9BQG0,O75533 4 +Golgi apparatus subcompartment 0.2901153048233454 0.1943771487210449 0.8458805813577777 1.0 1.0 86 Q01968,Q9Y6D5,Q14746,P20645,Q5VYK3,Q6XZF7,Q9Y296,Q9Y6B6,P50570,O00443,Q92614,Q9NR09,O75592,Q96JB2,Q9HC07,Q99986,Q92538,Q9UID3,Q15334 19 +H4 h2a histone acetyltransferase complex 0.333940521954858 0.1892240616958457 0.8499172098140051 1.0 1.0 11 Q9Y4A5 1 +Perikaryon 0.3624316956096102 0.1877311171559817 0.8510874359725338 1.0 1.0 21 O75592,O94832,Q06787,Q9UBB6,Q8IXJ6,Q00535,P46821 7 +Cul3 ring ubiquitin ligase complex 0.3108630990427368 0.1873836916799328 0.8513598082879794 1.0 1.0 5 Q13618,Q92990 2 +Endoplasmic reticulum tubular network 0.3365832592202904 0.1873443082060853 0.851390685001618 1.0 1.0 12 Q9C0E8,Q9H6H4,Q15042 3 +Heterochromatin 0.3856122013664699 0.1850416589539347 0.8531963606268369 1.0 1.0 36 P42771,Q8IXJ6,Q9H4L7,P26358,P42695 5 +Ficolin 1 rich granule membrane 0.3481885243746532 0.1778494015645876 0.8588412489130917 1.0 1.0 17 P63167,Q5T4S7,O94973,O60610,P42785,P53618,Q5T9A4 7 +Ficolin 1 rich granule lumen 0.3413607241305859 0.1648359222789996 0.869073128876996 1.0 1.0 71 P04075,O95352,Q15008,O00487,P20839,Q86VP6,P13639,P61160,P06737,P25787,P20618,P14174,P53396,P63172,P35573,P67870,Q14004,Q9NZ32,Q7Z6Z7,P09972,Q9UNP9,P46976,O43242,Q13200,P06744,P18669,P28066,P17858,P22392,P09429,P28482 31 +Septin cytoskeleton 0.3059456229459141 0.1645479725540272 0.8692997847352182 1.0 1.0 6 Q15019,Q9UHD8,Q16181,Q14141,Q9P0V9 5 +Chromatin 0.1794520016571701 0.1632155740996025 0.8703487042752693 1.0 1.0 227 O75569,P17655,P68400,Q92905,P51532,P42771,Q12873,P26358,Q9UBD5,Q9Y4A5,Q9Y5V3,P42695,P78362,Q9NRZ9,P52701,P25440,Q96L91,Q14839,P40763,Q6PGP7,Q86TU7,Q8NB78,Q08945,Q92908,P17096,Q29RF7,Q8WUX9,P49407,P16402,P50747,Q8IXJ6,Q9H4L7,O14929,P19784,P11802,O14744,P33993,Q96SB4,Q12830,O75182,O43913,Q9NTI5,Q6NXR4,Q8TEX9,Q92522,Q9UGU5,Q9UIF9,P85037,Q7Z5K2,P53350,Q9Y5B9,Q8IWI9,Q7LBC6,Q6UXN9 54 +Neuron projection cytoplasm 0.3743578792431326 0.1606642160760935 0.8723578746622664 1.0 1.0 34 Q9NZ32,P78559,O14617,P27695,Q9Y496,Q14204,Q9UQB8,Q15334,O60333 9 +Beta catenin destruction complex 0.2995818399044119 0.1590770100117798 0.8736082009118371 1.0 1.0 5 P48729,P49841,Q9HB71,P49840 4 +Cop9 signalosome 0.3106249741065809 0.1493174731118929 0.8813031282837509 1.0 1.0 9 P19174,Q92905,Q9UNS2 3 +U2af complex 0.2856716417910486 0.1463384571872085 0.883654208176391 1.0 1.0 3 Q01081,Q15637 2 +Chromosome telomeric repeat region 0.293608124253282 0.1453168276017738 0.8844607292430775 1.0 1.0 5 Q5UIP0,P13010,Q15554,P12956 4 +Smn sm protein complex 0.3023449028181741 0.1314459071349782 0.8954225750315772 1.0 1.0 9 P62314 1 +Dendrite cytoplasm 0.3060057442895317 0.1247836595361694 0.9006948240718582 1.0 1.0 11 Q9UQB8 1 +Ubiquitin ligase complex 0.3359648022184475 0.1166621103712958 0.907127816731942 1.0 1.0 67 Q86VP6,Q9NT62,Q96EP0,Q13616,Q14999,Q96P70,Q13309,Q6NTF9,Q5TAQ9,Q15369,Q6W2J9,Q9UL63,Q9Y3I1 13 +Leading edge membrane 0.354745181882583 0.1096268613757032 0.9127053067514646 1.0 1.0 38 Q9UM54,Q9HCM4,Q16512,P63167,O94832,Q9UPN3,P15531,P50570,P60953,O60610,Q92974,P31751,P19174,Q9Y2A7,P61586,Q9Y217 16 +Germ cell nucleus 0.2869532527764634 0.1087697748311305 0.9133850977390824 1.0 1.0 8 Q92547,O14965,Q15554 3 +Cilium 0.2601774892967277 0.1073760645526197 0.9144906424288972 1.0 1.0 88 Q3SYG4,O95352,Q13526,Q92973,Q01968,Q9Y5Y2,P21266,Q86Y56,Q9Y6D5,O00139,Q5SW79,Q14203,O14965,Q9Y5K8,P17612,Q9Y496,P04350,Q9H4M9,Q9BZH6,Q9P1Y5,O43924,Q13501,P06744,P43034,P57076,P63167,P22681,Q00796,Q15019,Q99570,P46821,P08237,Q13618 33 +Proteasome regulatory particle lid subcomplex 0.2818290496114716 0.1062190885615019 0.915408526140734 1.0 1.0 7 O00231,O00232,P48556,Q9UNM6,O43242,O00487 6 +Spindle microtubule 0.3433532011934218 0.1007449407947274 0.9197529352360754 1.0 1.0 32 O14965,P50748,Q8WUX9,Q00610,Q96CW5,Q9Y496,Q7Z460,P53350 8 +Nurd complex 0.293135629422754 0.0957434565699335 0.9237243260614194 1.0 1.0 12 Q12873,Q14839,P68400,O94776 4 +U5 snrnp 0.2861711225006289 0.0953899322771873 0.9240051124926818 1.0 1.0 10 P62314,Q9Y312 2 +Rna polymerase ii transcription regulator complex 0.3425097521171161 0.091141321730682 0.927380299264004 1.0 1.0 36 P17096,Q15648,Q9ULK4,Q9Y6J9,Q9Y4A5,Q14839,Q8N3C0,P40763,O60244,Q9Y2X0,Q92759,P18074 12 +Golgi stack 0.3376335265710675 0.0889892623237772 0.929090443687086 1.0 1.0 33 Q14746,Q96JB2,Q01968,Q6XZF7,Q99986,Q9Y296,Q9Y6B6 7 +Flemming body 0.309237362902145 0.088417327744629 0.9295449896828408 1.0 1.0 19 Q8TAG9,Q9BPX3,Q9NR09 3 +Extrinsic component of organelle membrane 0.292512167562685 0.085006883255411 0.9322559184733352 1.0 1.0 14 Q08AM6,P62942 2 +Proteasome complex 0.340805583871877 0.0797790082603742 0.9364130200803548 1.0 1.0 48 P28072,Q15008,O00487,Q15386,P49721,P60900,P25787,P20618,Q5VYK3,Q14997,Q05086,O43242,Q13200,P28066,P25789,O75832,P49720,P61289,O43396 19 +Clathrin coat of endocytic vesicle 0.2562724014336815 0.0783777611061882 0.9375275631691397 1.0 1.0 5 O95782,O94973,Q96CW1,P63010 4 +Myelin sheath 0.2840156173792842 0.077535608530426 0.938197465012915 1.0 1.0 13 P04350,Q8IXJ6 2 +Chromosome telomeric region 0.2781657661338498 0.0768232424161537 0.9387641606017368 1.0 1.0 81 O96017,P27695,O43913,P09874,Q14839,Q8IXJ6,Q9UBB9,Q13535,P28340,Q13315,Q9UBD5,P78527,Q6UXN9 13 +Site of polarized growth 0.3382370932978404 0.0757998484578729 0.9395783366928574 1.0 1.0 48 Q9UBF2,P27695,P53621,P22681,P50570,Q93008,Q96N67,Q8IXJ6,Q96Q89,P46940,P38935,Q8TAG9,P46821 13 +Distal axon 0.3316126345981831 0.071904650967014 0.9426777886968004 1.0 1.0 56 Q9UBF2,O14617,P27695,P53621,P22681,P50570,Q93008,P27708,Q96N67,Q8IXJ6,Q96Q89,P46940,P38935,Q8TAG9,P46821 15 +Dna packaging complex 0.3187694715981239 0.0687592914486526 0.9451812220775058 1.0 1.0 30 Q15003,Q15021,Q96L91,P16402,Q9BPX3,Q8NB78,Q9NTJ3,Q9Y4A5,Q6IBW4,P42695 10 +H4 histone acetyltransferase complex 0.2801251392388909 0.0685974811231065 0.9453100239182696 1.0 1.0 14 Q9Y4A5 1 +Neuron spine 0.3214954214017652 0.0664116353074747 0.9470501070189736 1.0 1.0 33 P27695,Q06787,P17612,Q9UQB8,P60953,P40818,Q08209,P62136,Q13614,P46821,Q7L576,Q15334,Q9Y6D5 13 +Cytoplasmic stress granule 0.3269438654456744 0.0611345526618795 0.9512520515586184 1.0 1.0 44 Q9HCE1,Q06787,Q13464,P67809,P26196,Q6PKG0,Q9Y520,Q92499,Q14258 9 +Peptidase complex 0.3170234682654814 0.0587065092118548 0.9531858746811046 1.0 1.0 61 P49721,P17655,Q9UPT9,P25787,Q5VYK3,Q9Y6J9,P49720,P61289,Q14997,O43396,Q15008,O43242,Q9Y4A5,Q15386,P28066,O75832 16 +Trans golgi network 0.3167495089418962 0.0583299885885873 0.9534857807346476 1.0 1.0 61 Q14746,O75592,P20645,Q5VYK3,P50570,Q96JB2,O00443,Q92614,Q00610,Q9HC07,Q01968,Q92538,P57737,Q9UID3,Q15334,Q9Y6D5,Q9NR09 17 +Brush border 0.3075598040183069 0.0543394912920072 0.956664686515053 1.0 1.0 31 O43795,P60660,O94832,O00299,P35579,P12814,O00429,Q13045,Q14344,Q14651,P47755,Q9UHB6,Q9Y5X3,Q9UPY5 14 +Cell cell junction 0.1664247399478602 0.0539840690701387 0.956947856772458 1.0 1.0 120 Q9HCM4,Q8NI35,Q9P1Y5,Q8TEW0,Q6XZF7,P46940,Q96RD7,Q9Y613,Q9BTW9 9 +Early endosome membrane 0.3203738931834806 0.0536298992343663 0.9572300346395636 1.0 1.0 44 Q7Z3U7,Q9H4M9,Q7Z3T8,Q96T51,Q9HC07,Q13614,Q9H223,Q01968,Q08AM6,Q15334,Q8NB49,Q9BZF3,O75165,Q9P258,Q99816 15 +Tertiary granule membrane 0.2524654150440499 0.0531839179425265 0.9575853691023912 1.0 1.0 10 Q5T4S7 1 +Endopeptidase complex 0.318282215613386 0.0510324511752855 0.9592996619304404 1.0 1.0 52 P17655,P28072,Q15008,O00487,Q15386,P49721,P60900,P25787,P20618,Q5VYK3,Q14997,Q05086,O43242,Q13200,P28066,P25789,O75832,P49720,P61289,O43396 20 +Haus complex 0.2299542674860356 0.0493814312540134 0.9606153258192492 1.0 1.0 5 Q9BT25 1 +Autophagosome 0.2862097393779602 0.0456075791156917 0.963623028199364 1.0 1.0 25 Q9H269,P27695,Q8WUX9,P42858 4 +Spindle midzone 0.2660574972385378 0.0416811177028715 0.9667529067686288 1.0 1.0 19 O14965,Q15058,Q13432,P60953,Q96Q89,P53350,Q9P258,Q99741 8 +Eukaryotic translation initiation factor 3 complex 0.2485305456545273 0.039798975162594 0.9682533932873364 1.0 1.0 14 Q14152,O15371,Q92905 3 +Non motile cilium 0.2473419432940121 0.0390326563503266 0.968864352441912 1.0 1.0 14 Q15019,Q9UIS9,Q01968,Q15555,Q96FJ2,P46821 6 +Cytoplasmic region 0.292352941587186 0.0356087255095866 0.9715943507850092 1.0 1.0 64 P04350,P78559,O14617,P27695,O60333,O00203,O95352,Q9P1Y5,Q9Y496,Q14204,Q7Z460,Q9UQB8,Q15334,Q9Y6D5,Q9NZ32 15 +Ap type membrane coat adaptor complex 0.2300799625441744 0.0329816077305791 0.9736892545664924 1.0 1.0 12 O00203,O14617,O95782,O94973 4 +Protein dna complex 0.2939899839089061 0.0325621127189812 0.9740237834677326 1.0 1.0 59 Q96L91,P35244,P28340,Q9UBD5,Q9Y4A5,P78527,P29375 7 +Cell division site 0.2685808570248992 0.0314321341365513 0.9749249144705552 1.0 1.0 27 Q16512,Q9H8V3,P35580,P35579,P35241,Q96GX5,Q96CW5,Q16513,Q9BSJ2,P61586,Q9UHB6 11 +Neuron to neuron synapse 0.2853194669284693 0.0291316003540064 0.9767596330493172 1.0 1.0 63 Q06787,P50914,P18124,P62277,P62269,P50570,P40818,P62851,Q02878,Q13614,Q15334,Q00535,Q14152,P46821,Q9UQB8,P62917,Q9Y6D5 17 +Cleavage furrow 0.2482322077447118 0.0288856792712437 0.9769557671430362 1.0 1.0 21 Q16512,Q9H8V3,P35580,P35579,P35241,Q96GX5,Q16513,P61586,Q9UHB6 9 +Anchored component of membrane 0.2014345487148766 0.0283435586519788 0.9773881397611331 1.0 1.0 7 Q9ULX3,P51149,P61020,Q9NQX3,Q15334,P20339 6 +Condensed nuclear chromosome 0.2456571747547958 0.0278592906851804 0.9777743771573308 1.0 1.0 21 O60921,Q92547,Q7Z5K2 3 +Sin3 type complex 0.2062600011635832 0.0274716426384869 0.9780835572044252 1.0 1.0 9 O75182 1 +Filopodium 0.271401025493015 0.027294346720474 0.9782249658538658 1.0 1.0 33 Q9UM54,O43795,Q06787,O15357,P60953,P35241,Q00535,Q14204,Q9UQB8 9 +Condensed chromosome centromeric region 0.2489198685616363 0.0270222836861595 0.9784419607081932 1.0 1.0 80 Q14008,O14980,Q15021,P50748,Q8WUX9,Q6P1K2,Q7Z460,P14635,O43237,P53350,Q9BPX3,Q8IWS0,P42695 13 +Site of dna damage 0.2829213016854192 0.0265328811541168 0.9788323074566384 1.0 1.0 43 Q9H4L7,Q14241,P35244 3 +Vesicle coat 0.2648451615931035 0.0254383368082591 0.9797053326420369 1.0 1.0 32 O14579,Q9UBF2,P53992,P53621,Q15436,O94973,Q8NC96,Q00610,P53618,O95782,O95486,Q9Y678,Q9Y6B6 13 +Membrane coat 0.2755334606326164 0.0242927914830386 0.980619062999076 1.0 1.0 41 O14579,Q9UBF2,O14617,P53992,P53621,Q9UBC2,Q15436,O00203,O94973,Q8NC96,Q00610,P53618,O95782,O95486,Q9Y678,Q9Y6B6 16 +Ciliary basal body 0.2203237410071986 0.0236209568533622 0.9811549556624388 1.0 1.0 17 Q9BZH6,Q15154,A0AVF1,Q9P1Y5,Q13526,Q15691,Q9UPT5,Q9Y6A4,Q9UIS9,P49454,Q96EX3,P61006,Q96C92,Q8WWQ0,P15311,P48729 16 +Microvillus 0.2261499429687944 0.0235061972009604 0.9812464952004096 1.0 1.0 19 Q9UM54,O43795,P35241,O94832 4 +Histone deacetylase complex 0.2515361652349794 0.0225092117297496 0.9820417639649116 1.0 1.0 30 Q9Y6J9,Q96L91,Q14839,Q7LBC6,Q9Y4A5 5 +Cell projection membrane 0.274779953390855 0.0220803737201967 0.982383842162318 1.0 1.0 61 Q9UM54,Q3SYG4,P31751,P19174,Q9Y2A7,Q9UPY5,Q9HCM4,Q9UPN3,P15531,O60610,P61586,Q9H4M9,O94832,P50570,P06744,Q16512,P63167,Q15019,Q92974,Q9UHB6,Q9Y217 21 +Lateral plasma membrane 0.2230254535431556 0.0220507635446035 0.9824074619134636 1.0 1.0 20 P46940 1 +Copii coated er to golgi transport vesicle 0.2478942196729474 0.0210209035374162 0.9832289807476162 1.0 1.0 31 O95070,Q5VYK3 2 +Proteasome regulatory particle 0.2083958020989513 0.020558376267129 0.983597944368902 1.0 1.0 18 Q99460,O00231,P51665,P55036,Q16186,P48556,O00232,P62333,Q9UNM6,Q15008,P43686,O43242,P35998,O00487,Q13200,P62191,P62195 17 +Cluster of actin based cell projections 0.2484433129875851 0.0188858556305865 0.9849321631016116 1.0 1.0 36 O43795,P60660,O94832,O00299,P35579,P12814,Q6IBS0,Q13045,O00429,Q14344,Q14651,P47755,Q9UHB6,Q9Y5X3,Q9UPY5,P43034 16 +Intercellular bridge 0.2060011515659114 0.0188346167709529 0.9849730385261072 1.0 1.0 21 Q14203,Q13432,Q15019,Q96Q89,Q7Z5K2,Q6IBW4,Q99741 7 +Actomyosin 0.2297613864928867 0.0185732485718816 0.9851815437016253 1.0 1.0 29 P35579,Q92614,Q9UHB6,Q9Y613,Q13418 5 +Nuclear ubiquitin ligase complex 0.1721038931607174 0.0182464640238141 0.9854422358650738 1.0 1.0 15 Q14999 1 +Proteasome accessory complex 0.1908763505402064 0.0175720714265065 0.9859802370095264 1.0 1.0 21 Q99460,P48556,Q15008,P43686,P35998,O00487,O00231,Q9UNM6,P62195,P51665,P55036,O00232,Q9UL46,O43242,Q13200,P17980,Q16186,P62333,P61289,P62191 20 +Site of double strand break 0.2191779273071835 0.0166932224581802 0.986681354103914 1.0 1.0 31 O60921,Q9H4L7,P35244 3 +Rna polymerase ii holoenzyme 0.1944721741151078 0.0162200828786178 0.9870588137504924 1.0 1.0 27 Q9UM54,Q96P16,Q9Y6J9,Q9Y4A5,Q92759,P18074 6 +Tight junction 0.1988291608257412 0.0159460399531762 0.9872774400917104 1.0 1.0 29 Q9BTW9,Q8NI35 2 +Chaperone complex 0.1352163461538481 0.0157787737879634 0.9874108823931608 1.0 1.0 25 Q9Y265,P50990,P49368,Q9HCN8,P40227,P50991,P11142,P31948,Q00613,Q9UBS4,P17987,Q969U7,O95456,Q16543,Q15185,P08238,Q8WXX5,Q99832,P48643,O95816,P78371,Q9UNE7,O95817,P53041 24 +Apical junction complex 0.2081739142839605 0.0152460203541033 0.987835906986868 1.0 1.0 34 Q9BTW9,Q9P1Y5,Q8NI35 3 +Actin filament bundle 0.1594619360805963 0.015219394420543 0.9878571489435864 1.0 1.0 29 P35579,Q9Y613,Q9UHB6,Q13418 4 +Cajal body 0.200602607473313 0.0147634881052584 0.9882208686764896 1.0 1.0 35 P57678,Q7L014,Q01844,Q15020,O43290 5 +Rna polymerase complex 0.2258298884382642 0.0144977553752433 0.9884328700272464 1.0 1.0 42 Q9UM54,Q92759,Q96T76,Q96P16,P25205,P30876,Q9NW08,Q9Y6J9,P49642,P09884,O14802,Q9BUI4,Q9Y4A5,P18074,Q9GZS3 15 +Actin filament 0.1818315561163644 0.0142381129146386 0.988640013355128 1.0 1.0 36 Q9UM54,O43795,Q16512,Q7KZI7,P46940,Q9Y2A7,O00401,Q9Y5K6 8 +Actin based cell projection 0.1862507996512918 0.0121916143532915 0.9902727401061352 1.0 1.0 49 Q9UM54,O43795,O94832,Q06787,O15357,Q9UQB8,P60953,P35241,Q9Y696,Q00535,Q14204,Q7L576,P43034 13 +Spindle pole 0.1782835427736833 0.0098569592594707 0.9921354117440466 1.0 1.0 64 Q14203,O14965,Q14008,Q15398,P50748,Q92547,Q14155,Q96CW5,Q96Q89,Q9BSJ2,Q9Y5Y2,P14635,P53350,Q9NR09,Q9BT25,Q13618,Q99741 17 +Lamellipodium 0.1899273727393303 0.0094973052708477 0.992422360671002 1.0 1.0 67 P31146,O15357,Q00535,Q9Y2A7,Q12923,Q7L576,P35241,Q8WUW1,P50570,Q16513,Q9UQB8,Q9BPX3,Q14155,Q13418,Q16512,P22392,P35580,Q13464,O00401 19 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cde3b9c0b44835204aa4071fdf24cbf369690bed --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bbsome", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor disc membrane", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Symmetric synapse", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CASP3", "CASP8", "CASP8AP2", "CAST", "CBL", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ3", "FUCA2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMPR2", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXA10", "HOXD11", "HP1BP3", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ITCH", "ITGB1", "ITPK1", "ITPR2", "ITSN2", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "MFN1", "MFN2", "MFSD10", "MGA", "MGAT1", "MGAT5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMP1", "NENF", "NES", "NF1", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPM3", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTULIN", "OXA1L", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPM1L", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPN13", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS2", "TBC1D23", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE4", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM38B", "TMEM43", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTF2", "TTI2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGGT1", "UHRF1", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR44", "WDR45", "WDR46", "WDR47", "WDR5", "WDR61", "WDR70", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WRAP53", "WTAP", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF207", "ZNF326", "ZNF638", "ZNF703", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["AAR2", "ABHD14B", "ACACA", "ACLY", "ACO1", "ACTN1", "ACTR10", "ACTR2", "ACTR3", "ADRM1", "AFDN", "AGL", "AIP", "AK6", "AKAP9", "AKT2", "ALDOA", "ALDOC", "ALKBH5", "ANAPC1", "ANAPC4", "ANKFY1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APEX1", "ARF4", "ARF5", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC3", "ARPC4", "ARRB1", "ASCC3", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATM", "ATP11C", "ATP6V1D", "ATR", "AURKA", "B4GAT1", "BAG2", "BAG3", "BAG6", "BAIAP2", 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setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Catalytic activity acting on a nucleic acid 111 281 7.1215408815620425 1.0672706717112472e-12 90.79854368932038 254.83495145631068 -0.792002958061835 0.5076390878250437 31.97147845771858 27.21519674254639 1.0704749073579398 0.3300278898464162 0.0435124316329231 1.3163785986329792e-05 3.377113214405699e-12 2.018746112347657e-15 +Adenyl nucleotide binding 171 504 5.581969886378645 2.3780956020351133e-08 140.32766990291262 465.8883495145631 -0.9411517135545642 0.4382662157837138 42.1989268649243 44.399741539024845 1.075891226372232 0.3308258874697798 0.6676073904519659 0.0856875640487522 0.0016739295948667 1.8236296515419856e-08 +Structural constituent of ribosome 51 110 5.294126876458199 1.195863876309559e-07 50.27427184466019 111.97330097087378 -1.0968665227712266 0.3627287132905895 16.025617180726236 5.646698990732621 1.8496256179403383 0.3775330956912056 0.0369413340125406 1.949876831352593e-06 2.98999201957594e-08 1.2940291696501451e-23 +Catalytic activity acting on rna 73 201 5.180566259647561 2.212133306448468e-07 68.55339805825243 179.48058252427185 -0.9086211551020408 0.4844944415018952 23.72351999755853 18.83582910076147 1.1239428117447956 0.3467084194722249 0.025670635271445 2.8264010299255486e-05 3.6686266365204286e-10 1.5507464645754378e-11 +Transferase activity transferring phosphorus containing groups 83 208 4.935764276055575 7.983748985526893e-07 51.5 184.14320388349515 -0.3975748481307545 0.6270265862759228 18.608185379203317 28.241871026111543 0.7368892239721001 0.307879242256324 0.2203017783522765 0.0576486765256984 0.0378505586999515 0.0029037929107052 +Ribonucleotide binding 188 606 4.7671856600834674 1.8681714295532004e-06 165.94417475728156 563.9247572815534 -0.97000696594212 0.411560275363265 44.77597190727751 53.146177503123546 0.9984934457791314 0.3282974558748524 0.6870386022604532 0.1234494670546393 0.0054239014282935 1.7165614825190548e-06 +Kinase activity 59 152 4.739099236782884 2.146703588001841e-06 35.16019417475728 132.373786407767 -0.2468132143986984 0.650700950478703 14.107719017779814 21.937269175241475 0.8173764292711447 0.324368436915093 0.2580686756109034 0.2591003648045188 0.1622054686200937 0.0081404994989627 +Structural molecule activity 68 212 4.603148649320158 4.161509777889094e-06 68.65533980582525 211.89320388349515 -0.6723107511869665 0.5266128709993241 22.75284353574739 11.498976418236946 0.9988804050601904 0.3294165689279784 0.1248821536318702 0.0001111600533455 1.38707934181644e-05 4.311564943256642e-17 +Protein kinase activity 42 101 4.361425157383563 1.29217997861808e-05 24.711165048543688 85.15776699029126 -0.2630746242467029 0.6428628304343708 10.70326016942092 16.186469924165078 0.7783417694745319 0.3043865168638158 0.129901968105059 0.1954979859417819 0.2848724183923185 0.0399293189923616 +Helicase activity 41 97 3.439887740422797 0.0005819555179253 36.172330097087375 89.90291262135922 -0.7636897687946307 0.5036794328436971 12.713875586725129 7.1411083460370985 1.0406647219197582 0.3540660373049626 0.5147372580778585 0.0030750491535246 6.332426039230007e-07 4.9694689492518404e-08 +Gtpase binding 38 99 3.3182330575319066 0.0009058886485697 26.12864077669903 92.05339805825244 -0.2275295351963657 0.6264591899440848 11.24659409488207 10.843192267514558 0.9385934888894932 0.3335293253611523 0.034459684655003 0.2340327465645219 0.0493874849165142 0.0001352439817749 +Mismatched dna binding 2 5 2.88091322242298 0.0039652479579956 2.2572815533980584 4.536407766990291 -0.2019501521378929 0.5464517847315143 1.2372928436396369 0.7796779947347844 0.876314291465594 0.2977267502038712 1.0 1.0 0.2559514735144251 0.0182159139614431 +Enzyme regulator activity 74 249 2.746339773964721 0.0060264314648363 53.1747572815534 229.7597087378641 -0.1881850729991543 0.7387930885402405 24.220438767026938 24.477809009299605 0.7445455506102049 0.3136969650203332 0.3296181688384829 0.4928164269642331 0.1047811571304582 0.151464842270361 +Protein serine threonine kinase activity 40 87 2.743174433965613 0.0060848352877536 21.385922330097088 69.94902912621359 -0.2265230805291581 0.6116443932751089 9.55815596799563 14.238769174373656 0.8662596685370179 0.315939433499304 0.0675825589199256 0.0884990621211528 0.0925019200504019 0.007573527427917 +Catalytic activity acting on dna 37 92 2.665376781202774 0.0076902107803138 26.00242718446602 85.75 -0.3500608277779486 0.5919299439851401 12.582639216108683 9.385649291410756 0.931241404473262 0.3350047723683129 0.2640629452891732 0.0498624876262496 0.0048510522195963 0.0001981611566645 +3 5 exodeoxyribonuclease activity 2 6 2.598758824162518 0.0093561482082402 2.483009708737864 5.808252427184466 -0.3245742132053604 0.5204455107637473 1.5143977847286945 0.8271074021716397 0.8550079529386392 0.290966433174295 1.0 0.0832836732680532 0.0010713621736615 0.0077568745967145 +Enzyme activator activity 24 107 2.588431130079441 0.0096414224465246 22.140776699029125 104.06067961165049 0.003581904186774 0.7454595688175544 10.77661921600813 13.677588057552711 0.7114939792030793 0.303364661852867 0.2753365640204097 0.4991170511697603 0.0444965179419728 0.1157827151535683 +Tubulin binding 43 105 2.539453378561911 0.0111025841710943 27.21359223300971 101.01456310679612 -0.1774709573366694 0.6863389880998976 10.418570505002434 12.05246546720838 0.7627321032602739 0.3156342675860825 0.7453117717076347 0.5073923014605616 0.3722597581030138 0.03278206096629 +Protein tyrosine serine threonine phosphatase activity 5 7 2.519531482305116 0.0117511131294294 1.8810679611650485 4.468446601941747 -0.3523034759706301 0.5163059400013565 1.2079553555543134 1.4931801322488931 0.9919404315866904 0.3223205189153811 1.0 0.0274603336438859 0.0270423729706739 0.0089325963600969 +Mrna methyltransferase activity 2 6 2.4698634930411107 0.0135164619451662 2.2233009708737863 5.060679611650485 -0.1138491897010818 0.5539839429900162 1.5837894757799378 1.3684047562629107 0.8771002956819489 0.2963002373447506 1.0 0.1094892401774078 0.0026581093268102 0.0182159139614431 +Histone h3 methyl lysine 4 demethylase activity 2 5 2.437267481316411 0.0147987281750685 0.9902912621359224 3.366504854368932 0.4934433344412655 0.4871635525973559 1.1212436371311745 1.0353670225266298 1.00941667866664 0.3191674234627318 1.0 1.0 0.1988473022417859 0.0680064706612652 +Ribonuclease p activity 2 5 2.4153157859266505 0.0157215727889783 1.8470873786407769 3.8033980582524274 -0.4105810196126633 0.524572991396342 1.1547354011780817 1.050976479278309 0.8948786492411579 0.3102548910309998 0.0012105019492812 0.0047533286028597 0.0020298329670106 0.0141665154869097 +Rna binding 224 995 2.373574542396839 0.0176168366908013 331.8203883495146 957.0970873786408 -2.926245807393257 0.1698803240410153 92.26090469842312 51.71359975174448 3.026180805637489 0.3115649032545627 1.578758001420491e-06 1.2102919242666284e-08 1.0210490616011583e-15 1.7620947071032615e-25 +Atp dependent chromatin remodeler activity 2 5 2.3675505036752043 0.0179062759585804 2.133495145631068 3.932038834951456 -0.4122274498690543 0.5150619926222765 1.1943005498510386 0.8923856530848377 0.8646193791725397 0.2949055926409391 1.0 0.002465796513642 0.014977467250991 0.0546176715347421 +Phosphatidylinositol kinase activity 2 5 2.360568231546009 0.0182469612951472 1.391727493917275 3.681265206812652 0.0931358734351817 0.5613133371003806 1.1006875461087613 1.168572383844215 1.0063672285326168 0.3229961537669069 1.0 0.1349531130589082 0.005208827916976 0.0338099842169397 +Phosphatidylinositol 3 kinase binding 4 5 2.3496059354172165 0.0187932954893614 1.2985436893203883 3.6432038834951457 0.1739033581348124 0.531763127698389 0.903444227051241 0.9810720444950884 0.9821024677982256 0.308887079542444 1.0 1.0 1.0 0.0624183143373935 +Translation repressor activity mrna regulatory element binding 0 6 2.276183125543014 0.0228350514563981 1.5995145631067962 6.174757281553398 0.6534600204791633 0.3949783065671634 1.3392142882982137 0.7026604707853292 0.9849198932748844 0.2965869521608698 0.0561990347849709 0.1094892401774078 0.2559514735144251 0.4511907478135378 +Trna specific ribonuclease activity 5 6 2.2192509988109546 0.0264696532478678 2.4757281553398056 4.851941747572815 -0.5623617935990006 0.4687343768263707 1.3677609808946014 1.0993913216685187 0.8602404309463316 0.2979649168114435 0.001984476440523 0.0077184558590264 0.0042425564235442 0.0280386150660574 +Pre mirna binding 1 6 2.1804412164821025 0.0292247717431854 2.395631067961165 4.645631067961165 0.0451174645519511 0.5714751002964188 1.4112173151187923 0.7699800399668832 0.8626355963307901 0.3053316374984833 0.028497516818446 0.0563150378970086 0.0082857576662697 0.0312108672695238 +Cyclin dependent protein serine threonine kinase regulator activity 6 9 2.106090717724909 0.0351964729794971 2.4805825242718447 5.519417475728155 0.228341462053297 0.5714132507541911 1.69582916411688 1.600094551358398 0.8688933058851026 0.3181784185621054 0.1675604235637086 0.3076603852203092 0.013184387389335 0.0359117122080593 +Dna directed dna polymerase activity 1 6 2.0538281913266454 0.0399923233780796 2.9199029126213594 7.495145631067961 0.1147726318284263 0.586152160764852 2.064703836467016 1.4287192065009142 0.8321595329711028 0.2979673720697421 1.0 0.1993869387044997 0.1067922158236129 0.3097803043008575 +Map kinase scaffold activity 2 5 1.987633420195004 0.0468522473331127 2.0800970873786406 3.9635922330097086 -0.2573995671197817 0.5449603798342987 1.1536737395685823 0.8708520037106525 0.8814540800353662 0.3035079486485067 1.0 1.0 0.1988473022417859 0.3623306062719575 +Nadph binding 0 7 1.9689502818718507 0.0489588006689052 1.3786407766990292 5.429611650485437 0.8367704566864596 0.3914568233833007 1.0938176207501296 1.2950229014206938 0.8806674554162238 0.2962147259816868 0.0652597674910206 0.1265462710440741 0.2917500038862815 0.1467539296032722 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..50eb4ba02a94d9c6e98cc463668499743156d750 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 1394, + "title": "Average number of proteins per term", + "value": 17.380918220946917 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..34ee4f9df574fcbe92b94f4d0c7df17407f38f7d --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..46c71b549c7a39412528e8625f8db2c8c9c0c31d --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,445 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Catalytic activity acting on a nucleic acid 0.4395939844577254 7.1215408815620425 1.0672706717112472e-12 1.4877767092595326e-09 1.4877767103654782e-09 281 P46063,P51532,O15091,Q12873,P38935,P26358,Q96DE0,Q96FZ2,Q9GZR7,Q9BWH6,Q9NRZ9,Q9UET6,O75818,Q6P158,Q96P11,Q92499,Q96QE3,Q07864,Q9BTE6,Q8N1G2,Q7Z478,Q9Y620,Q9H4L7,Q8IY81,Q8IX18,O14802,Q7Z2T5,Q7L2J0,Q9HCK8,P47897,P27695,Q14147,Q9NW08,P35251,Q7Z7L1,Q86WJ1,Q14527,Q96FX7,Q8IZH2,Q86W50,O43776,P28340,Q9P2J5,O60294,Q9Y3Z3,Q9UBP6,P33992,Q5TAX3,P15531,P46087,Q96L91,Q9Y2L1,Q7L014,Q92620,P26640,Q9HCE1,Q9H974,Q99575,Q15185,O95707,P33993,Q7Z4G4,Q15477,Q14562,Q12830,O60231,O14646,Q8WVM0,Q9NSD9,Q96C86,Q6P6C2,P42694,Q8IY37,A5YKK6,P54132,Q2NKX8,Q9P2D1,Q96GQ7,Q9H0D6,P52701,Q9Y3I0,Q15554,Q14839,Q9NUL7,Q8N3C0,P23381,P54136,Q08J23,Q9BV44,P18074,Q92614,Q14240,P29372,Q9H9L3,Q66K74,Q9UIV1,Q9BUI4,P57081,O14981,O43709,P07814,P26196,P41252,P18858,Q6P1R4,Q8TEA1,Q96F86,P49917,P26639,Q9UNY4,Q9H6S0 111 +Adenyl nucleotide binding 0.3147730859391771 5.581969886378645 2.3780956020351133e-08 3.3150103611112365e-05 8.287663173440868e-06 504 Q9UM54,O75116,P46063,P51532,Q9BYN0,Q00535,P38935,Q13535,Q12873,Q9GZR7,P78362,Q9NRZ9,P53396,P08243,Q9NYV4,Q00534,Q6P158,Q0VDF9,Q92499,O60942,Q96QE3,Q00169,Q9BTE6,O00443,Q9NUQ8,Q9UJ70,Q7Z478,Q9Y620,Q9H4L7,Q8IX18,Q7KZI7,O14976,Q9HCK8,Q8NE71,P47897,P35790,Q14147,Q13464,Q04637,P35251,Q7Z7L1,Q86WJ1,Q9Y223,Q14527,P54277,P11908,P36507,P49841,P68400,Q13523,P42356,Q969G6,O43776,Q9Y5Y2,Q9P2J5,P33992,P17612,P15531,P12277,Q96L91,Q03518,Q9Y496,Q14204,Q7L014,P49770,Q8NB49,Q92620,P26640,P78527,Q9H2G2,Q9HCE1,Q9H4M9,Q15418,P19784,O43237,Q13315,P11802,P31689,Q96SB4,P33993,Q15477,Q13418,O96017,Q14562,O60231,O43913,O14646,P35580,Q9BW19,Q8WVC6,Q96GX5,P49761,Q9NSD9,P42694,O15067,O43795,P07741,P23921,Q8IY37,Q13085,O43933,P20585,P54132,P61081,Q8TBX8,Q2NKX8,Q5SY16,Q9P2D1,Q9HA64,Q96GQ7,Q99661,P52701,Q15058,P49427,Q14692,Q14839,Q9NUL7,Q8N3C0,P23381,P54136,P18074,Q99741,O00764,Q9Y3D8,Q15257,Q9NVE7,Q92614,Q9UIG0,Q96Q89,Q9NTJ3,Q14240,P17858,O00154,O15111,O60333,P28482,P49903,Q9H223,Q99986,Q7Z460,P53350,P08237,P04035,P04183,P31751,O14965,O14981,P06737,P07814,P17812,P26196,P27708,P41252,P18858,P49917,O94832,P26639,P42345,P50747,Q16513,Q9BVQ7,Q9UG63,Q9UNY4,Q16512,P22392,Q13555,P35579,P51003,Q99570,Q5T9A4,Q9H6S0 171 +Structural constituent of ribosome 0.4975755996637753 5.294126876458199 1.195863876309559e-07 0.0001666895400812 3.334068487178931e-05 110 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,Q9HD33,P26373,P18124,P62266,P62277,P61513,P39023,P61254,P62899,P82675,Q9NP92,Q9Y3U8 51 +Catalytic activity acting on rna 0.4047976056398868 5.180566259647561 2.2121333064484673e-07 0.0003083238754497 5.1395230486718394e-05 201 Q9UIV1,Q96FX7,Q8IY37,Q8IZH2,Q86W50,A5YKK6,O15091,O43776,P38935,Q9P2J5,O60294,Q96DE0,Q9GZR7,Q9Y3Z3,Q96GQ7,Q9BWH6,Q9UBP6,Q9H0D6,Q9BUI4,P57081,Q9UET6,Q5TAX3,Q9Y3I0,O43709,P07814,O75818,P46087,P26196,Q9NUL7,P41252,Q9Y2L1,Q6P1R4,P23381,Q7L014,P54136,Q8TEA1,Q92620,Q08J23,Q96F86,P26640,Q6P158,Q96P11,Q9BV44,Q92499,Q9HCE1,Q9H974,P26639,Q9BTE6,Q8N1G2,Q99575,Q7Z478,Q9Y620,Q8IY81,Q8IX18,O14802,Q14240,Q7Z2T5,O95707,Q7L2J0,Q7Z4G4,Q15477,P47897,Q14562,O60231,P27695,Q14147,Q9NW08,Q8WVM0,Q9NSD9,Q9H9L3,Q96C86,Q6P6C2,Q9H6S0 73 +Transferase activity transferring phosphorus containing groups 0.3882350391291217 4.935764276055575 7.983748985526893e-07 0.0011123159703251 0.0001589906583691 208 Q2VPK5,O75116,Q00535,O75909,Q13535,Q9BWH6,Q9NR45,P78362,Q9NYV4,Q14558,Q00534,O60942,Q07864,O00443,Q9UJ70,Q7KZI7,O14802,O14976,Q13464,P35790,Q9NW08,Q9Y223,P11908,P36507,P49841,P68400,Q13523,Q969G6,P42356,P28340,Q9Y4A5,Q5TAX3,P17612,P12277,P15531,P78527,Q9H2G2,Q15418,Q15185,P19784,Q13315,P11802,Q96SB4,Q13418,O96017,Q8WVC6,Q96GX5,P49761,P48651,Q8TBX8,Q5SY16,Q9HA64,Q15554,P25440,P67870,O00764,Q9Y3D8,Q9NVE7,Q9UIG0,O60256,Q13501,P17858,O15111,P28482,P49903,Q99986,Q7Z460,P53350,P08237,P04183,P31751,Q9BUI4,O14965,P27708,Q96IJ6,P42345,Q16513,Q16512,P22392,Q13555,P51003,Q99570,Q9UKK9 83 +Ribonucleotide binding 0.2899220604250476 4.7671856600834674 1.8681714295532004e-06 0.0026008453313117 0.0003255288715998 606 Q9UM54,O75116,P46063,P51532,Q9BYN0,Q00535,P38935,Q13535,Q12873,Q96DE0,Q9GZR7,P78362,Q9NRZ9,P53396,P08243,Q9NYV4,Q00534,Q6P158,Q0VDF9,Q9Y6B6,Q92499,O60942,Q96QE3,Q00169,Q9BTE6,O00443,Q9NUQ8,Q9UJ70,Q7Z478,Q9Y295,Q9H4L7,Q8IX18,Q9Y620,Q7KZI7,O14976,Q9HCK8,Q8NE71,P47897,Q05639,P35790,Q14147,Q13464,Q04637,P60953,P35251,Q7Z7L1,Q86WJ1,Q9Y223,Q8TCY9,Q14527,P54277,P11908,P36507,P49841,P68400,Q13523,P42356,Q969G6,O43776,Q9Y5Y2,Q9P2J5,Q9Y3Z3,P33992,O00178,P13639,P17612,P15531,P12277,Q96L91,Q03518,Q9Y496,Q14204,Q7L014,P49770,Q8NB49,Q92620,P26640,P78527,Q9H2G2,Q9HCE1,Q9H4M9,Q9NZB8,P36915,Q15418,O00429,P19784,O43237,Q13315,P11802,P31689,Q96SB4,P33993,Q15477,Q13418,O96017,Q14562,O60231,O43913,O14646,P35580,Q9BW19,Q8WVC6,Q96GX5,P49761,O60841,Q9NSD9,Q9Y450,P42694,O15067,Q2NL82,O43795,P07741,P23921,Q8IY37,P84085,Q13085,O43933,P20585,P54132,P61081,Q8TBX8,Q2NKX8,Q5SY16,Q9P2D1,Q9HA64,Q96GQ7,Q99661,P52701,Q9Y3I0,Q15058,Q9BUF5,P49427,Q14692,Q13885,Q14839,Q9NUL7,Q8N3C0,P23381,P54136,P18074,P04350,O00764,Q15257,Q92614,Q96Q89,Q9NTJ3,Q14240,P17858,O00154,O15111,O60333,P28482,P49903,Q9H223,Q99986,Q7Z460,P53350,P08237,P04035,P04183,P31751,O14965,O14981,P06737,P07814,P17812,P26196,P27708,P41252,P18858,P49917,O94832,P26639,P42345,P50570,P50747,Q16513,Q9BVQ7,Q9UG63,Q9UNY4,Q16512,P22392,Q13555,P35579,P51003,Q99570,Q5T9A4,Q9H6S0 188 +Kinase activity 0.430179370071581 4.739099236782884 2.1467035880018415e-06 0.0029880349246157 0.0003325005335195 152 P36507,P49841,P68400,Q13523,O75116,P04183,P31751,Q969G6,P42356,O75909,Q00535,Q13535,Q9Y4A5,Q9HA64,P78362,O14965,P17612,P25440,P12277,P15531,P27708,Q9NYV4,Q00534,P67870,P78527,Q9H2G2,O00764,P42345,O00443,Q15418,Q9UJ70,Q7KZI7,P19784,Q16513,O14976,Q13315,P11802,Q13501,P17858,Q96SB4,O15111,Q13418,O96017,Q16512,P22392,Q13555,Q13464,P35790,P28482,P49903,Q8WVC6,Q99986,P49761,Q7Z460,Q99570,Q9Y223,P53350,P08237,P11908 59 +Structural molecule activity 0.3704104825367419 4.603148649320158 4.161509777889094e-06 0.0057843624826278 0.0005801144630378 212 P18621,P08708,P46782,P62847,Q07020,O75116,P61353,P46776,P40429,P62424,P53618,P62701,P62241,Q9Y5K6,Q02543,Q9UBF2,P15880,Q9UPN3,P61970,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P20248,P32969,P62280,Q96RD7,P46778,P27635,P62917,P47914,Q9Y678,P62750,P04350,P17096,P53621,P61247,P84098,P62854,P36915,P36578,P60866,P61313,P62851,P62906,Q00610,Q96CW5,P62753,Q5SRE5,P50914,P62910,Q9HD33,P78559,P26373,P18124,P62266,P61513,P39023,P61254,P62899,P82675,Q14152,Q9Y3U8,P46821,Q15334 68 +Protein kinase activity 0.4896264071888109 4.361425157383563 1.29217997861808e-05 0.0178518390556949 0.0016375444456306 101 P36507,P49841,P68400,Q13523,O75116,P31751,O75909,Q00535,Q13535,P78362,O14965,P17612,P25440,P27708,Q9NYV4,Q00534,P67870,P78527,Q9H2G2,P42345,Q15418,Q7KZI7,P19784,Q16513,O14976,Q13315,P11802,Q13501,Q96SB4,O15111,Q13418,O96017,Q16512,P22392,Q13555,Q13464,P28482,Q99986,P49761,Q7Z460,Q99570,P53350 42 +Helicase activity 0.482348255971928 3.439887740422797 0.0005819555179253 0.5558007865127308 0.0250214156520945 97 Q9H6S0,P42694,Q8IY37,P46063,P51532,P54132,Q12873,P38935,Q2NKX8,Q9P2D1,Q9GZR7,P33992,Q9NRZ9,O14981,P26196,Q96L91,Q14839,Q9NUL7,Q8N3C0,Q7L014,Q92620,Q6P158,P18074,Q92499,Q9HCE1,Q7Z478,Q9Y620,Q9H4L7,Q8IX18,Q14240,P33993,Q15477,Q9HCK8,Q14562,Q9UNY4,O60231,O14646,Q14147,Q7Z7L1,Q86WJ1,Q14527 41 +Gtpase binding 0.4453547122689303 3.3182330575319066 0.0009058886485697 0.7173034176982473 0.0250214156520945 99 P67809,O43592,O75116,O15397,Q92973,Q01968,Q9Y2A7,Q9UI26,Q9P2R3,Q9P258,O14980,Q9HAV4,P50748,P61970,P07814,P55060,P41252,Q9Y5L0,Q9Y496,Q9UIA9,Q96F07,Q8WUW1,Q9H4M9,Q9H8V3,Q96P70,P55196,O00429,Q96N67,Q16513,Q9P0V3,Q16512,O75592,Q13464,Q92974,Q15042,P46940,Q8TEX9,O95373 38 +Cyclin dependent protein serine threonine kinase activator activity 0.9373321396597994 3.173636651555241 0.001505420177692 0.8775603371956261 0.0250214156520945 2 O75909 1 +1 phosphatidylinositol 3 kinase activity 0.9364368845120832 3.169751025184252 0.0015256960763472 0.8809777017616133 0.0250214156520945 2 O00443 1 +Phosphatidylinositol 3 kinase activity 0.9364368845120832 3.169751025184252 0.0015256960763472 0.8809777017616133 0.0250214156520945 2 O00443 1 +Histone h3 di monomethyl lysine 9 demethylase activity 0.9227096389137568 3.1099397175658723 0.0018712552968784 0.926537010623424 0.027750317913283 2 Q7LBC6 1 +Calcium channel inhibitor activity 0.8964488212473846 2.994290567066 0.0027508383556344 0.9785053806301258 0.0342381131049508 2 Q9NWR8 1 +Mismatch repair complex binding 0.8823654184604075 2.8922652332084215 0.0038247490801346 0.9952133404887288 0.0421968025388868 4 Q13535 1 +Mutlalpha complex binding 0.8823654184604075 2.8922652332084215 0.0038247490801346 0.9952133404887288 0.0421968025388868 4 Q13535 1 +Map kinase phosphatase activity 0.873470605789312 2.891750475302039 0.0038310208006386 0.9952551661921416 0.0421968025388868 2 Q99956 1 +Mismatched dna binding 0.8839205630316982 2.8809132224229796 0.0039652479579956 0.996067751088006 0.0422412868484905 5 P20585,P54277 2 +Armadillo repeat domain binding 0.871326555781952 2.8618484470233896 0.0042117824976206 0.997215324110068 0.0425451072585739 3 Q9HCK8 1 +Dna insertion or deletion binding 0.8637948321357688 2.808121240567313 0.0049831462280598 0.999054570543912 0.0472551417817375 4 P20585 1 +Peroxisome proliferator activated receptor binding 0.8469113697403721 2.771631827848654 0.0055776082433989 0.9995890135566204 0.0497223016163808 2 P17096 1 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.8466917996355058 2.749874531169102 0.0059618087811355 0.9997601828816884 0.051942259005643 3 P42771 1 +Enzyme regulator activity 0.2813416998903416 2.746339773964721 0.0060264314648363 0.9997809610924488 0.0521454844908658 249 O75569,P36507,Q15436,Q14185,Q9Y263,Q8TF05,P42771,Q92990,P21359,O75909,A1X283,Q01968,Q13144,Q9HAD4,Q15008,Q9P2J5,Q9P258,Q9UER7,Q9Y6D5,Q9UKL3,P62081,P62841,P61927,P20248,Q6XZF7,Q14997,Q9Y2L1,P46777,P49770,Q9NPQ8,Q14558,P67870,P63151,Q9H8V3,Q8TC07,P42574,Q15257,Q9H9T3,P60866,Q15418,P49407,O00429,Q96N67,Q7KZI7,O95248,P14635,O43924,Q69YN2,O43242,Q92616,P11802,Q9UDY8,Q9P0V3,Q13200,Q9NR09,Q14155,P47897,O75592,P63167,Q14738,Q13464,O95067,P61803,Q92974,Q15042,Q15334,P35251,P46940,P61289,Q92538,Q86X10,Q9BTW9,O00401,O95373 74 +Protein serine threonine kinase activity 0.5447227635630434 2.743174433965613 0.0060848352877536 0.9997981876263942 0.0521454844908658 87 P36507,P49841,P68400,Q13523,O75116,P31751,O75909,Q00535,Q13535,P78362,O14965,P17612,P25440,Q9NYV4,Q00534,P67870,P78527,Q9H2G2,P42345,Q15418,Q7KZI7,P19784,Q16513,O14976,Q13315,P11802,Q13501,Q96SB4,O15111,Q13418,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q7Z460,Q99570,P53350 40 +Phosphatidylinositol 3 kinase regulatory subunit binding 0.8417910447761192 2.7274210608445455 0.0063831528530804 0.9998671959100004 0.0524306099488032 3 P50570,P22681 2 +Nuclear receptor activity 0.832587287376892 2.706126696681117 0.0068073069261567 0.999926764608698 0.0543672502763789 2 P10589 1 +Catalytic activity acting on dna 0.4826927716277223 2.665376781202774 0.0076902107803138 0.9999788016350244 0.0585800755615163 92 P46063,P51532,P54132,Q12873,P38935,P28340,P26358,Q2NKX8,Q9P2D1,Q96FZ2,P33992,P52701,O14981,P15531,Q14839,P18858,Q8N3C0,P18074,Q92499,P49917,Q96QE3,Q07864,Q92614,Q9Y620,Q9H4L7,Q15185,P33993,Q9UNY4,Q9HCK8,Q12830,P27695,O14646,P29372,P35251,Q66K74,Q86WJ1,Q14527 37 +Rna 2 o methyltransferase activity 0.8230378991345861 2.662172682352877 0.0077638037502323 0.9999808837916668 0.0588192523251297 2 Q9UET6 1 +1 4 alpha oligoglucan phosphorylase activity 0.8205970149253778 2.629632200273351 0.0085477290268372 0.9999936480691044 0.062063188731407 3 P06737,Q13126 2 +3 5 exodeoxyribonuclease activity 0.8265913066727584 2.598758824162518 0.0093561482082402 0.9999979626640396 0.0665432173586068 6 P27695,Q07864 2 +Enzyme activator activity 0.3314633846990273 2.588431130079441 0.0096414224465246 0.9999986363606298 0.0671779205765111 107 O75569,Q9Y263,Q14185,P21359,Q01968,O75909,A1X283,Q9UER7,Q9UKL3,Q14997,Q8TC07,P42574,Q15257,P49407,P14635,Q69YN2,Q9UDY8,P61803,Q15042,Q15334,P61289,P35251,P46940,Q9BTW9 24 +Dipeptidyl peptidase activity 0.8113432835820926 2.5865845495413233 0.0096932385975203 0.999998732279616 0.0671779205765111 3 Q9NY33,P42785 2 +Tubulin binding 0.3285253395002488 2.539453378561911 0.0111025841710943 0.9999998258869393 0.0719737530374566 105 Q9UHD1,Q15398,O43670,O15344,Q00535,Q9BSJ2,Q9P258,Q6NUK4,Q99661,Q14203,Q15058,Q9UPN3,P42858,Q9Y496,Q9UH99,Q8IWS0,P50570,Q9P1Y5,O00429,Q9Y295,Q96CW5,Q96Q89,Q9BT25,Q14155,O60333,P43034,P78559,Q16512,Q14008,Q06787,Q9BW19,P29372,Q92974,Q7Z4H7,Q7Z460,Q14166,Q9P265,P53350,P46821,Q9BTW9,Q9BPU6,Q9H6H4,Q66K74 43 +Rrna cytosine methyltransferase activity 0.7961802447030621 2.5373245219350897 0.0111703352756848 0.999999841746814 0.0719737530374566 2 Q96P11 1 +C methyltransferase activity 0.7961802447030621 2.5373245219350897 0.0111703352756848 0.999999841746814 0.0719737530374566 2 Q96P11 1 +Protein tyrosine serine threonine phosphatase activity 0.813220716271813 2.519531482305116 0.0117511131294294 0.9999999302298954 0.074009425146804 7 O60942,P51452,Q99956,O95248,Q9UNI6 5 +Racemase and epimerase activity acting on carbohydrates and derivatives 0.7889185368299481 2.481375954229539 0.0130876254265639 0.9999999894230436 0.0791127119848881 3 Q96C23 1 +Protein arginine omega n monomethyltransferase activity 0.7839450910176043 2.4798454650662216 0.0131439334525123 0.9999999902317128 0.0791127119848881 2 Q99873 1 +Mrna methyltransferase activity 0.7992741311859515 2.4698634930411107 0.0135164619451662 0.999999994229144 0.0800416764940846 6 Q8N1G2,Q96FX7 2 +Chemoattractant activity 0.7905739275965995 2.4680990687266804 0.0135832720790842 0.999999994749056 0.0800416764940846 4 P09429 1 +H4 histone acetyltransferase activity 0.7853731343283641 2.4646265680845003 0.0137156113268837 0.9999999956447848 0.0803342949146045 3 Q9UPT9,Q9GZZ1 2 +Histone h3 methyl lysine 4 demethylase activity 0.7883421861805451 2.437267481316411 0.0147987281750685 0.999999999058545 0.0852455664299403 5 P29375,Q8NB78 2 +Ribonuclease p activity 0.783735675736035 2.4153157859266505 0.0157215727889783 0.9999999997450556 0.0876634898713432 5 O75818,O15091 2 +Four way junction helicase activity 0.7666368248284048 2.397885924553535 0.0164899998501353 0.999999999914174 0.0904687988666247 2 P46063 1 +Bubble dna binding 0.7666368248284009 2.39788592455352 0.0164899998501359 0.999999999914174 0.0904687988666247 2 P09429 1 +Phosphatidylinositol phosphate kinase activity 0.7657415696806791 2.3936259910368554 0.0166827505723228 0.9999999999346932 0.0904893163339222 2 O00443 1 +Dna translocase activity 0.7651447329155446 2.3907849076702656 0.0168123991453081 0.9999999999456584 0.0908390868548822 2 Q9Y620 1 +Rna binding 0.2170831115799101 2.373574542396839 0.0176168366908013 0.9999999999826384 0.0931393607696309 995 P00374,P41567,Q9Y383,Q2VPK5,P67809,P62847,P46782,O75116,O75607,P46776,O43592,O43670,O75153,P42696,P51532,P62424,P62861,P38935,Q12873,Q8IYB3,P26358,Q8IXT5,Q96DE0,Q9UII4,Q9GZR7,Q9ULC4,P78362,Q6AI08,Q9UPN3,Q9HAV4,Q8IWR0,O75818,P42766,O95163,Q01804,P32969,P40763,P46777,Q08945,P62917,Q6P158,Q96P11,Q99873,Q92499,Q9UKJ3,P84098,P62854,P48634,Q9H9T3,P61313,Q7Z478,Q7KZI7,Q8IX18,Q8IY81,P62753,O75691,Q7Z2T5,Q92616,P50914,P62910,Q7L2J0,P09012,P20290,P26641,Q8NE71,Q05639,P27695,Q06787,Q14147,Q04637,P62277,P39023,Q8WTT2,P62899,Q9UIF9,Q14152,Q7Z7L1,Q9NP92,Q9Y3Y2,Q9Y2V2,P49207,Q6P2Q9,Q14527,P04818,P18621,O75569,P21399,P08708,P62314,Q13523,Q5T8P6,Q8IZH2,Q86W50,Q92905,Q92973,P42771,O95071,Q9BYG3,Q69YN4,Q9Y3Z3,Q9Y314,Q9UPT8,Q96D46,Q9UBP6,O00178,O15371,Q5TAX3,P13639,P18615,P15531,O76094,P35241,P46087,P61927,Q9Y2L1,P49770,Q14204,Q7L014,Q9BY44,Q01844,P46778,Q5C9Z4,Q5T3I0,P27635,Q86UK7,O43290,P78527,Q8IWS0,Q9HCE1,Q86TB9,Q7Z6Z7,P36578,Q8NHU6,Q9NZB2,Q99575,Q8IWZ3,Q9UJA5,Q96SB4,Q7Z4G4,Q15477,O60231,P62266,P49761,O60841,Q9Y3U8,Q96C86,Q6P6C2,Q2NL82,Q9BRT6,Q9Y237,Q8IY37,A5YKK6,Q5VTL8,P50579,P62701,Q96HR8,P15880,P62081,P62269,P62841,P83731,Q02878,Q9NUL7,Q8N3C0,P62280,Q9Y520,P78316,P47914,P62750,P61247,Q92614,Q9GZR2,Q14240,Q15020,P09429,P26373,P61513,Q6PKG0,Q9H9L3,Q9UIV1,Q07020,P09874,P61353,P40429,P49327,Q13144,Q4G0J3,Q5F1R6,P62241,Q9P258,Q02543,O14980,O43709,P07814,P26196,P41252,P46779,Q8TEA1,Q8WUA2,Q96F07,Q96F86,O60524,P26639,P60866,P62851,P62906,Q00610,Q16513,Q5JTH9,Q5JVF3,Q92917,Q96CP2,Q14258,P41214,P18124,P35579,P51003,P61254,P63241,P82675,Q8IY67,Q9H6S0,Q9HAU5,Q9UKK9 224 +Atp dependent chromatin remodeler activity 0.7737500976392463 2.3675505036752043 0.0179062759585804 0.9999999999884868 0.0931393607696309 5 Q9H4L7,Q9HCK8 2 +Dna n glycosylase activity 0.7686843031513364 2.363858455708861 0.0180857210031983 0.999999999991076 0.0933759076979946 4 P27695 1 +Phosphatidylinositol kinase activity 0.7722947207182214 2.360568231546009 0.0182469612951472 0.999999999992902 0.0938607529351854 5 P42356,O00443 2 +Nucleoside diphosphatase activity 0.7619310371493355 2.3530849278321635 0.0186183811688815 0.9999999999958116 0.0954192034905181 3 Q96DE0 1 +Phosphatidylinositol 3 kinase binding 0.7700119474312975 2.3496059354172165 0.0187932954893614 0.9999999999967332 0.0958307538580025 5 P50570,Q12923,P22681,O14654 4 +Translation activator activity 0.763145254725175 2.3372916967017914 0.0194240219969743 0.999999999998667 0.0981053864629791 4 Q7Z478 1 +Trna cytosine methyltransferase activity 0.7546268656716439 2.318048613474916 0.0204466791775619 0.9999999999996888 0.1003395560704188 3 Q9UET6,Q8TEA1 2 +D1 dopamine receptor binding 0.7519402985074655 2.3051282450486665 0.021159392037382 0.9999999999998872 0.1010143578770909 3 Q9Y5X3,Q15334 2 +Cysteine type endopeptidase activity involved in apoptotic process 0.7513871449439907 2.2806444125520073 0.0225694969698586 0.9999999999999848 0.1062901309999424 4 P55212 1 +Diphosphotransferase activity 0.7450746268656739 2.272027724057395 0.0230848358791448 0.9999999999999928 0.1066455681004906 3 Q14558,P11908 2 +Ribose phosphate diphosphokinase activity 0.7450746268656739 2.272027724057395 0.0230848358791448 0.9999999999999928 0.1066455681004906 3 Q14558,P11908 2 +Ribonuclease p rna binding 0.7467900865929896 2.258404177500383 0.0239204725231636 0.9999999999999978 0.1093283235976725 4 O75818,Q99575,O95707 3 +Cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.7353028946582982 2.2475836165559713 0.0246027532364638 0.9999999999999992 0.1105258982324758 2 P42574 1 +Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity 0.7343283582089616 2.219983095872216 0.0264199151140394 1.0 0.1153084269610244 3 Q8NCE2,Q13614 2 +Trna specific ribonuclease activity 0.7472363310426989 2.2192509988109546 0.0264696532478678 1.0 0.1153084269610244 6 O75818,Q99575,O15091,O95707,Q9BQ52 5 +Acetylcholine receptor binding 0.7254550880334122 2.1998364804278987 0.0278184986944751 1.0 0.1188668390506184 2 Q15334 1 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.7345476261570394 2.1989230028086397 0.0278833976826056 1.0 0.1188668390506184 4 Q01968,Q8NCE2,Q13614 3 +Pre mirna binding 0.7392977590757355 2.1804412164821025 0.0292247717431854 1.0 0.1225412772004365 6 Q9HAV4 1 +Rrna adenine methyltransferase activity 0.7260699356999983 2.179793488701108 0.0292727728176078 1.0 0.1225412772004365 3 Q86W50 1 +Cation chloride symporter activity 0.7232794341488548 2.16617571011806 0.0302977625119433 1.0 0.1252474520769924 3 Q9Y666 1 +Anion cation symporter activity 0.7232794341488548 2.16617571011806 0.0302977625119433 1.0 0.1252474520769924 3 Q9Y666 1 +Potassium chloride symporter activity 0.7232794341488548 2.16617571011806 0.0302977625119433 1.0 0.1252474520769924 3 Q9Y666 1 +Phosphofructokinase activity 0.7226106659490537 2.1629092648762085 0.0305481590431688 1.0 0.1252474520769924 3 P17858 1 +Fructose binding 0.7226106659490537 2.1629092648762085 0.0305481590431688 1.0 0.1252474520769924 3 P17858 1 +Fructose 6 phosphate binding 0.7226106659490537 2.1629092648762085 0.0305481590431688 1.0 0.1252474520769924 3 P17858 1 +Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity 0.7213293742158919 2.156648042949712 0.0310330981632174 1.0 0.1254238293210935 3 Q01968 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.7213293742158919 2.156648042949712 0.0310330981632174 1.0 0.1254238293210935 3 Q01968 1 +Phosphatidylinositol trisphosphate phosphatase activity 0.7213293742158919 2.156648042949712 0.0310330981632174 1.0 0.1254238293210935 3 Q01968 1 +Nedd8 transferase activity 0.7162041181736789 2.1547637411621174 0.0311803269673192 1.0 0.1254238293210935 2 P61081 1 +Rna polymerase iii transcription regulatory region sequence specific dna binding 0.7114294240525115 2.131417893090634 0.0330547300736285 1.0 0.1277910791749821 2 P42345 1 +Cyclin dependent protein serine threonine kinase regulator activity 0.7346571446694933 2.106090717724909 0.0351964729794971 1.0 0.1328371848462289 9 O95067,P42574,P20248,P42771,O75909,P14635 6 +Protein tyrosine kinase inhibitor activity 0.705759474783648 2.103622307408098 0.0354114064788624 1.0 0.1328371848462289 2 Q86XI2 1 +Phosphatidylinositol 5 phosphate binding 0.7065671641791111 2.0842236633273905 0.0371398272621636 1.0 0.136604008452391 3 Q9Y5X3,A1X283 2 +Dna apurinic or apyrimidinic site endonuclease activity 0.7051926360334171 2.077453510549151 0.0377597217774163 1.0 0.1381549925399433 3 P27695 1 +Channel inhibitor activity 0.7086468632018893 2.071886331461471 0.0382760429663771 1.0 0.1396774971076693 4 Q9NWR8 1 +Nedd8 specific protease activity 0.7030986636219989 2.067131143754527 0.0387217981932579 1.0 0.1403053462402652 3 Q96FW1 1 +Co smad binding 0.6977021784541788 2.063989263670082 0.0390187343532153 1.0 0.1403053462402652 2 Q93008 1 +Dna directed dna polymerase activity 0.7136074227759067 2.0538281913266454 0.0399923233780796 1.0 0.1417120387009622 6 Q07864 1 +G quadruplex rna binding 0.7000000000000072 2.0518370302424898 0.0401855032089628 1.0 0.1417120387009622 3 Q8IZH2,Q06787 2 +Peptide alpha n acetyltransferase activity 0.6957000363829842 2.030576181118743 0.0422980059820852 1.0 0.1452300993572088 3 Q14CX7 1 +Amidine lyase activity 0.6993629111908348 2.0259641644420148 0.0427684570519339 1.0 0.1459349614073867 4 O75592 1 +14 3 3 protein binding 0.6993162007073936 2.0257326101445035 0.0427921930357855 1.0 0.1459349614073867 4 P78362 1 +Protein arginine n methyltransferase activity 0.6975433993432151 2.016940726316571 0.0437016993179739 1.0 0.1475064621047353 4 Q99873,O60678 2 +Histone h3 methyl lysine 9 demethylase activity 0.6923134056235585 1.990961612730921 0.0464851076581565 1.0 0.1531920569160051 4 Q7LBC6 1 +Map kinase scaffold activity 0.6960557650206789 1.987633420195004 0.0468522473331127 1.0 0.1537744666660638 5 O60271,P46940 2 +Lipase activator activity 0.6798309382500194 1.951741795694058 0.0509688677073114 1.0 0.1606780725036179 3 Q9Y263 1 +Death receptor binding 0.6842215673894427 1.9506449041176523 0.0510993016174365 1.0 0.1606780725036179 4 P42574 1 +Trna methyltransferase activity 0.7101995842829457 1.9378186842184009 0.0526453474165222 1.0 0.1630835873302934 12 P57081,Q9UET6,Q96FX7,Q8TEA1,Q7Z2T5,Q08J23,O60294,Q7Z4G4,Q9UBP6 9 +Calmodulin dependent protein kinase activity 0.6755223880597057 1.930239054473548 0.0535772245777999 1.0 0.1645080419855794 3 P46020,Q13555 2 +Catalytic activity acting on a rrna 0.6982822064236135 1.923900186135011 0.054367095913304 1.0 0.1662011660156706 9 O43709,Q86W50,P46087,Q8IY81,Q96P11 5 +Trna guanine methyltransferase activity 0.6944819399232944 1.9218978325128455 0.0546186146223706 1.0 0.1666047019334456 8 Q9UBP6,P57081,Q7Z4G4,Q7Z2T5 4 +Nfat protein binding 0.6669650850492295 1.9113895263544949 0.0559545416563806 1.0 0.1691987658763449 2 Q92908 1 +Mitogen activated protein kinase p38 binding 0.6669650850492292 1.911389526354493 0.0559545416563809 1.0 0.1691987658763449 2 Q99873 1 +Protein adp ribosylase activity 0.670149253731348 1.9033655705822623 0.0569928602905012 1.0 0.1712242397520661 3 Q7Z2W4,P09874 2 +Tau protein kinase activity 0.686708316722713 1.90078137328584 0.0573306548317615 1.0 0.1718686727644637 7 Q7KZI7,O75116,Q00535,Q13464 4 +Calcium dependent cysteine type endopeptidase activity 0.6636824828409351 1.894964900630568 0.0580970518814949 1.0 0.1736643604342295 2 P17655 1 +Phosphatidylinositol 3 5 bisphosphate binding 0.6810269050347278 1.8911088274035683 0.0586098183988561 1.0 0.1738342273361818 6 Q9Y5X3,O60493,Q92538,A1X283 4 +Nuclear export signal receptor activity 0.6822720404550491 1.8784242888417977 0.060323145382267 1.0 0.1758188199565838 7 Q9UIA9,O14980,Q9HAV4 3 +Telomerase activity 0.6647761194029896 1.8764290584304597 0.0605963875397499 1.0 0.1758188199565838 3 Q15185,Q15554 2 +Rna directed dna polymerase activity 0.6647761194029896 1.8764290584304597 0.0605963875397499 1.0 0.1758188199565838 3 Q15185,Q15554 2 +Cyclin dependent protein kinase activity 0.6883576155965436 1.87370555404937 0.0609710199960833 1.0 0.1758188199565838 9 O75909,Q9NYV4 2 +Protein arginine omega n asymmetric methyltransferase activity 0.6640118170102972 1.8725924170488653 0.0611246892591874 1.0 0.1758188199565838 3 Q99873 1 +Histone arginine n methyltransferase activity 0.6628177871595511 1.8665961357651717 0.0619580076380028 1.0 0.1759426051967777 3 Q99873 1 +Protein serine threonine kinase activator activity 0.6876454932271439 1.8535409014579416 0.063804869335398 1.0 0.1807804631169612 10 P46940,O75909 2 +Lys48 specific deubiquitinase activity 0.6644875522845164 1.8517210256194072 0.0640658931890962 1.0 0.1811518359139964 4 Q93008,Q6GQQ9 2 +Sulfotransferase activity 0.6532378394509071 1.842548035623538 0.0653950269364147 1.0 0.1841629647461861 2 Q8NCH0 1 +Rna adenylyltransferase activity 0.6502536556251832 1.8275288857046503 0.0676202871746398 1.0 0.1885253606428959 2 Q96Q11 1 +Rna 7 methylguanosine cap binding 0.6752855428470195 1.8248349164866464 0.0680259450432783 1.0 0.1892777792222154 8 Q6PKG0,Q7L576,Q96F07,Q96C86,Q8TEQ6,O60573 6 +Plus end directed microtubule motor activity 0.6713563192101997 1.823245121825988 0.0682662738561525 1.0 0.1895642445148537 7 Q96Q89,Q9Y496 2 +Ubiquitin protein transferase inhibitor activity 0.6728388718171001 1.812412007773448 0.0699225588345571 1.0 0.192252558215725 8 P62081,P62841,P60866,Q92990,P46777 5 +Polynucleotide adenylyltransferase activity 0.6504477611940347 1.8042995748403017 0.0711843564123797 1.0 0.1951226775232379 3 Q96Q11,P51003 2 +Protein tyrosine phosphatase activity 0.6960838801151329 1.803011902393541 0.0713863454353309 1.0 0.1951226775232379 17 Q06124,O60942,P30307,Q99504,P51452,Q99956,Q13614,Q9ULE6,Q9UNI6,Q8NCE2 10 +Aspartic type endopeptidase inhibitor activity 0.6442852879737293 1.7974348877523798 0.0722666063143093 1.0 0.1962211796358284 2 Q13464 1 +Four way junction dna binding 0.6593698281390578 1.78171451518586 0.0747957986272052 1.0 0.2017577153115659 6 P09429,P52701,P54132 3 +Cytokine activity 0.6586749642751274 1.7781895488327215 0.0753727288463079 1.0 0.2024462119686961 6 P43490,P09429,P14174 3 +Histone serine kinase activity 0.6488211594142058 1.7726116212004914 0.0762930847185598 1.0 0.2037405365855794 4 Q99986 1 +Protein serine threonine tyrosine kinase activity 0.5396386885137644 1.767921430838362 0.0770740395127234 1.0 0.2054325259669912 76 P36507,P49841,P68400,Q13523,O75116,P31751,Q00535,Q13535,O14965,P78362,P17612,Q9NYV4,Q00534,P78527,Q9H2G2,P42345,Q15418,Q7KZI7,P19784,Q16513,Q13315,O14976,P11802,Q96SB4,Q13418,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q99570,Q7Z460,P53350 35 +Proteasome binding 0.6714599265219076 1.75487223574121 0.0792811641868196 1.0 0.2097092249704088 11 Q5VYK3,Q14997 2 +Microfilament motor activity 0.660649452575401 1.7503561807971388 0.0800568722312795 1.0 0.2097092249704088 8 Q9UM54,O43795,O94832,P35580,P35579 5 +Protein phosphatase 1 binding 0.6443714541654224 1.7500548448169655 0.0801088504542626 1.0 0.2097092249704088 4 Q9UQ13,P62136,Q96QC0 3 +Molecular function regulator 0.2350213981133869 1.7251098803038458 0.0845076722968394 1.0 0.2153632453049253 311 Q14185,O75909,Q00535,Q9Y6D5,Q14997,Q6XZF7,P20248,P46777,Q14558,Q8NFQ8,Q9H9T3,P49407,Q7KZI7,O95248,O43242,Q92616,Q9NR09,P47897,Q13464,P60953,Q92974,Q99996,P35251,P46940,Q9NWR8,Q9BTW9,O95373,O75569,P36507,Q9Y263,Q15436,Q8TF05,P42771,Q92990,A1X283,Q9HAD4,Q9P2J5,P61927,Q9Y2L1,P49770,Q9H8V3,Q8TC07,P42574,Q15418,O00429,P14635,O43924,P11802,Q9UDY8,Q9P0V3,P31689,Q13200,Q14155,O75592,P63167,P51858,Q15042,Q92538,Q14738,O00401,O00410,P43490,P21359,Q01968,Q6DN90,Q92759,Q9UKL3,Q9NZL9,P62081,P62841,Q9NPQ8,P23381,P61586,P67870,P63151,P53621,Q15257,Q96N67,P62942,P09429,O95067,P61803,Q15334,Q13144,Q15008,Q9P258,Q9UER7,P14174,P60866,Q69YN2,P61289,Q86X10 92 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.6567159410852581 1.7124273420223135 0.0868179438739085 1.0 0.2182168715476837 9 P46940,Q7Z3T8,Q8TEW0 3 +Protein deacetylase activity 0.6404924997000054 1.707630625097566 0.087704902129396 1.0 0.2183225599435323 5 Q8IXJ6 1 +3 5 dna helicase activity 0.652018609071684 1.6883375965053171 0.0913464420606193 1.0 0.2250063743606945 9 Q8N3C0,P33993,P46063,P33992 4 +Protein serine kinase activity 0.5566615968126676 1.686498259240754 0.0916998700932958 1.0 0.2250063743606945 72 P36507,P49841,P68400,Q13523,O75116,P31751,Q00535,Q13535,O14965,P78362,P17612,Q9NYV4,Q00534,P78527,Q9H2G2,P42345,Q15418,Q7KZI7,P19784,Q16513,Q13315,O14976,P11802,Q96SB4,Q13418,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q99570,Q7Z460,P53350 35 +Ligase activity forming phosphoric ester bonds 0.6362007168458689 1.6857569093902998 0.0918426305676005 1.0 0.2250063743606945 5 P49917,Q9Y3I0,O00442,P18858 4 +Rna methyltransferase activity 0.6849555117719967 1.682607546291837 0.0924510898761381 1.0 0.2260996829602396 25 P57081,Q9UET6,Q96FX7,O43709,Q8N1G2,Q8WVM0,Q86W50,P46087,Q7L2J0,Q8IY81,Q8TEA1,Q7Z2T5,Q08J23,O60294,Q96P11,Q7Z4G4,Q9UBP6 17 +Dynein light intermediate chain binding 0.6350059737156386 1.6796622053390224 0.0930230572407926 1.0 0.2271000731938089 5 Q14204,P63167,Q96FJ2,Q8TD16 4 +Amp binding 0.6413821641957284 1.670588633116611 0.0948029592194517 1.0 0.2302357581043827 7 P07741,P06737,P08237,P17858,P11908 5 +Calmodulin dependent protein phosphatase activity 0.6183228886899366 1.665711554559299 0.0957708794812222 1.0 0.2321819234727369 2 Q08209 1 +Ubiquitin like modifier activating enzyme activity 0.6392389978483435 1.6596156663092636 0.0969917946612535 1.0 0.2343267968072571 7 P22314,O95352,Q9UBT2,Q13564 4 +Cytoskeletal protein binding 0.2393045205091213 1.650241579086738 0.0988935357798808 1.0 0.2376854980640583 266 Q9UM54,Q15398,O15357,O75116,O43670,Q00535,P57737,Q9Y6D5,Q9UPN3,P42858,Q9UH99,Q96RD7,Q9H269,Q96EK5,Q9Y295,Q7KZI7,P47755,O60271,Q9Y613,P78559,P27695,Q13464,Q06787,Q92974,P46940,Q9P265,Q9UHB6,Q9BTW9,Q9BPU6,P17655,P49841,Q9BSJ2,Q6NUK4,Q14203,Q9HCM4,P35241,Q13045,Q9Y496,Q8IWS0,Q9P1Y5,O00429,Q9BPX3,Q14155,P35580,Q9BW19,Q9Y5X3,O00401,O43795,P31146,Q13526,Q7L576,Q99661,Q9Y3I0,Q15058,O60610,Q92614,Q9NZQ3,Q96Q89,O60333,P29372,Q7Z460,P53350,P46821,Q15334,Q66K74,Q9P258,P51452,Q86TU7,O94832,P50570,P55196,Q96CW5,Q9BT25,Q16512,Q14008,P35579,Q9H6H4 77 +Calcium dependent protein serine threonine phosphatase activity 0.6185074626865729 1.6420717462275158 0.1005751362056219 1.0 0.240264880998476 3 Q08209,Q13555 2 +Proline rich region binding 0.6210651774026525 1.6313312981459616 0.1028204327177442 1.0 0.2429350562856533 4 Q9UQB8,P07737 2 +E box binding 0.614120947997432 1.6196531276096398 0.1053068102504584 1.0 0.2467188125867882 3 O14744 1 +K63 linked polyubiquitin modification dependent protein binding 0.6297621987544931 1.6110127082386554 0.1071769526088695 1.0 0.24942349238191 7 Q96EP0,Q6P2Q9,Q13501,Q6GQQ9 4 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters 0.6042972247090407 1.5940523257988513 0.1109243155887762 1.0 0.2568579666623822 2 Q96QE5 1 +Rna cap binding 0.6428359565979236 1.5914610841365044 0.1115058467527125 1.0 0.257736129127922 12 O15371,Q6PKG0,O43432,Q7L576,Q96F07,Q96C86,Q8TEQ6,O60573 8 +Atp hydrolysis activity 0.2589382093088725 1.5898961324141685 0.1118582195999948 1.0 0.257736129127922 178 Q8IY37,P46063,O43933,P51532,Q12873,P38935,Q9P2D1,Q9GZR7,O14981,P26196,Q14839,Q9NUL7,Q9Y496,Q8N3C0,Q7L014,Q6P158,Q0VDF9,P18074,Q92499,Q9HCE1,Q92614,Q7Z478,Q9H4L7,Q8IX18,Q96Q89,Q9NTJ3,Q14240,Q9BVQ7,Q9HCK8,O60333,O60231,O14646,Q14147,P35251,Q7Z7L1,Q86WJ1,Q5T9A4,Q9H6S0,P54277 39 +Histone threonine kinase activity 0.612768169388668 1.5888534191716397 0.1120934896749705 1.0 0.2578520208034802 4 Q99986 1 +Kinase binding 0.2531350438003905 1.5600656244073454 0.1187443739784552 1.0 0.2702357981098783 193 P49841,Q9UHD1,Q9H6R7,P09874,P46109,Q9Y570,Q13526,P42771,P19174,P49327,O75909,Q00535,O95782,Q9UNI6,Q9Y666,Q9P258,Q9UER7,Q92600,Q14203,O14965,P98170,Q15058,P13639,P17612,P62081,P51452,P42858,P20248,P40763,P23381,Q9NYV4,P61586,Q15555,Q10567,Q14004,Q99873,Q92796,Q99741,Q9Y3I1,Q92908,Q06124,Q96KP1,P30307,Q9Y478,P50570,O94973,Q00610,P14635,P62753,P09884,O60271,Q92616,Q13501,P17858,P13807,P18669,Q14155,Q13418,P47897,Q05639,O75592,O96017,Q15382,Q16512,P63244,Q8TD19,P22681,P60953,P50851,Q99986,P46940,Q14152,P53350,P08237,Q15334 75 +Racemase and epimerase activity 0.6114147186767052 1.5588671819150628 0.1190278192535618 1.0 0.2702357981098783 5 Q96C23 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.6146281655526488 1.5530944356952947 0.1204005752524204 1.0 0.2720233418182724 6 Q01968,Q8NCE2 2 +Protein demethylase activity 0.6254133151751685 1.5512987286170865 0.1208301113831569 1.0 0.2724740119453737 9 P29375,Q8NB78,Q7LBC6,Q9UPP1 4 +Protein kinase c activity 0.5986105469652866 1.5401528456366458 0.1235231009087507 1.0 0.2768347309755603 3 Q16513 1 +Calcium dependent protein kinase activity 0.5986105469652866 1.5401528456366458 0.1235231009087507 1.0 0.2768347309755603 3 Q16513 1 +Inorganic diphosphatase activity 0.5932557445538575 1.5374287707978211 0.1241883454041414 1.0 0.2774335793163032 2 Q9H2U2 1 +Map kinase kinase kinase activity 0.5917636526409984 1.529764137488943 0.1260751214674531 1.0 0.2807487529163413 2 Q13546 1 +Microtubule minus end binding 0.6091171857809823 1.5247371949985775 0.1273246604834468 1.0 0.2826283068693071 6 Q96CW5,Q9P1Y5,Q9UPN3 3 +Hydrolase activity hydrolyzing n glycosyl compounds 0.6102027061596168 1.510327228671239 0.1309599472058686 1.0 0.2888578582357293 7 P27695 1 +Histone h3 methyl lysine 36 demethylase activity 0.5927219001572842 1.4858439235081198 0.1373204090368545 1.0 0.3007287933514032 4 Q9UPP1 1 +Ubiquitin protein transferase regulator activity 0.6144210343169854 1.4767315578084423 0.1397476093362168 1.0 0.3033871696211174 10 P62081,P62841,P60866,Q92990,P46777 5 +Atp dependent activity 0.2387610501953681 1.4760102498458658 0.1399411406501998 1.0 0.3033871696211174 238 Q9UM54,O43795,Q9H6S0,P42694,Q8IY37,P46063,O43933,P51532,P54132,Q12873,P38935,Q9Y5Y2,Q2NKX8,Q9P2D1,Q9GZR7,Q96GQ7,Q99661,P33992,Q9NRZ9,P52701,Q15058,O14981,Q9Y5K8,P26196,Q96L91,Q03518,Q14839,Q9NUL7,Q9Y496,Q14204,Q7L014,Q8N3C0,Q8NB49,Q92620,Q6P158,Q0VDF9,P18074,Q92499,Q9HCE1,Q96QE3,O94832,Q92614,Q7Z478,Q9Y620,Q9H4L7,Q8IX18,Q96Q89,Q9NTJ3,Q14240,Q9BVQ7,P33993,Q15477,Q9HCK8,Q14562,Q12830,O60333,O60231,P35580,O14646,Q14147,Q9BW19,Q9UNY4,P35579,P35251,Q7Z7L1,Q86WJ1,Q5T9A4,Q14527,P54277 69 +Exodeoxyribonuclease activity 0.611064283990186 1.4593042745401892 0.1444813794300226 1.0 0.3104214132133358 10 P27695,Q07864 2 +Dynein intermediate chain binding 0.6104155813154819 1.4559355191337284 0.1454104455753699 1.0 0.3113704472074742 10 P63167,P42858,Q14204,P63172,Q86Y56 5 +Carbohydrate kinase activity 0.6011054270823463 1.4440152051040969 0.1487346983019926 1.0 0.3165437701266835 8 Q9UJ70,Q01813,P51570,Q9Y223,P08237,P17858 6 +Hydrolase activity acting on ester bonds 0.2487068796582025 1.4240789607232045 0.154423616039127 1.0 0.3254828125219207 186 Q9UIV1,Q9NZC3,O15357,Q99504,Q8IZH2,A5YKK6,Q13614,O15091,Q01968,P49327,Q12923,P28340,Q9UNI6,Q96DE0,P15531,P51452,O75818,Q99956,P41252,Q9ULE6,Q9Y2L1,Q5TFE4,Q96F86,P26640,Q92499,Q06124,O60942,P30307,Q07864,Q15257,Q99575,O95248,Q9GZR2,Q9H0R4,O00154,P27695,P35790,Q13555,Q9H9L3,Q96C86,Q8NCE2,Q66K74 42 +5 3 dna helicase activity 0.5833696069642741 1.41438254117315 0.1572496134190726 1.0 0.3281526363865078 5 P38935 1 +Phosphotyrosine residue binding 0.5931848135081393 1.4029918294475658 0.1606192754052577 1.0 0.3336859462219513 8 Q06124,P46109,P28482,P22681 4 +Peptide lysine n acetyltransferase activity 0.5978313914290131 1.390540711666715 0.1643647456805412 1.0 0.3389415021873884 10 Q9UPT9 1 +Kinase activator activity 0.6172288186932231 1.3882404837886964 0.165063828494663 1.0 0.3398803204158941 17 Q7KZI7,P46940,O75909,P14635,Q9UDY8,Q9UER7 6 +Protein prenyltransferase activity 0.5628170695314743 1.3805947177167672 0.1674036084138366 1.0 0.3426734656811868 2 P24386 1 +Protein geranylgeranyltransferase activity 0.5628170695314743 1.3805947177167672 0.1674036084138366 1.0 0.3426734656811868 2 P24386 1 +Actin monomer binding 0.5808561061566557 1.378878858110247 0.167932107680945 1.0 0.3426855366779053 6 Q6IBS0,P07737,Q9UHB6,P31146 4 +Peptide n acetyltransferase activity 0.6019188554300291 1.3783014839539545 0.1681102252330666 1.0 0.3426855366779053 12 Q9UPT9,P49407 2 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.5905398252218226 1.3705858949499343 0.1705040824256858 1.0 0.3469820305130015 9 O75909,Q9NYV4,Q00534 3 +Threonine type endopeptidase activity 0.5850516916003337 1.3608392355946868 0.1735644996744167 1.0 0.352181823211262 8 P20618,P49721,P49720,P28072 4 +Oxidized dna binding 0.5767934280272836 1.3578710434323518 0.1745046070591749 1.0 0.3535747416286189 6 P52701,P20585 2 +Dopamine receptor binding 0.5755856551449138 1.35162478395901 0.1764953777604203 1.0 0.3570893419419825 6 Q9Y5X3,Q96QK1,Q15334,P50570 4 +Dynactin binding 0.5752336224566805 1.3498041039290634 0.1770788281113919 1.0 0.3577505599815658 6 Q9Y5X3,P49841,P42858 3 +Endoribonuclease activity producing 5 phosphomonoesters 0.6003697964615073 1.3253938527508071 0.1850405548268012 1.0 0.3671323059168117 15 Q96DE0,O75818,P27695,O15091 4 +Lactate dehydrogenase activity 0.5520740077588702 1.3250747817839486 0.1851463493970722 1.0 0.3671323059168117 2 P00338 1 +L lactate dehydrogenase activity 0.5520740077588702 1.3250747817839486 0.1851463493970722 1.0 0.3671323059168117 2 P00338 1 +Demethylase activity 0.5894698462951418 1.3133144894963047 0.1890769980601292 1.0 0.3696680719436467 12 Q9UPP1,Q8NB78,Q8IUF8,Q7LBC6,Q6P6C2,P29375 6 +Nadplus adp ribosyltransferase activity 0.5592778276688638 1.2672751919588112 0.2050569078094786 1.0 0.3942749372226388 6 Q8IXJ6,Q7Z2W4,P09874 3 +Mhc class ib protein binding 0.5454495445518885 1.2658839370921389 0.2055546380278659 1.0 0.3944436092095514 3 Q03518 1 +Peptidase activity 0.2605813694387012 1.2622957638622814 0.206842380439155 1.0 0.3944436092095514 121 Q70CQ2,Q9UPT9,P17655,Q93008,Q92905,P50579,Q9H4A4,Q9NQW7,Q96DE0,Q96FZ2,P49721,Q86UV5,Q01804,Q6NTF9,Q96BN8,Q6GQQ9,P55212,P42574,Q96RU2,Q9UDY8,Q96FW1,Q9Y4P1,P40818,P29144,P42785,Q14674,P49720,P52888,Q9NY33,Q86TI2,Q6P2Q9 31 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.5894974515335676 1.254643046162219 0.20960836953153 1.0 0.3986276495592808 16 Q96DE0,O75818,P27695,O15091 4 +Ubiquitin like protein conjugating enzyme activity 0.5641406248560155 1.2524419230641557 0.2104088782234885 1.0 0.3995479496533642 8 Q9NR09 1 +Phosphatidylinositol monophosphate phosphatase activity 0.5467846858030987 1.248613640336053 0.2118064208869989 1.0 0.3995479496533642 4 Q8NCE2,Q13614 2 +Calcium channel regulator activity 0.551287469163575 1.2485529218804077 0.2118286405194172 1.0 0.3995479496533642 5 Q9NWR8 1 +Microtubule plus end binding 0.5652015935151036 1.2390644542459426 0.215321629465564 1.0 0.404513014542108 9 Q14203,Q14008,Q7Z460,Q99661,P43034 5 +Phosphatidylinositol phosphate phosphatase activity 0.5613977326545908 1.238233218363801 0.2156295977486977 1.0 0.404513014542108 8 Q01968,Q8NCE2,O15357 3 +Threonine type peptidase activity 0.5638256257508909 1.2319290943539634 0.2179755720830298 1.0 0.4056848431024614 9 P20618,P49721,P49720,P28072 4 +Nucleocytoplasmic carrier activity 0.5908869914048254 1.2045930578177753 0.2283604380152042 1.0 0.4205210707968225 21 O14980,Q9HAV4,Q96P70,Q53FT3,P55060,Q92973,Q9Y5L0,O00629,Q9UIA9,Q9UI26,Q8TEX9,O00410 12 +Ubiquitin like protein transferase activity 0.4752940185181719 1.2021432198110629 0.2293080437292616 1.0 0.4211533767570365 76 Q96EP0,O95071,Q9UII4,Q9Y314,Q15386,Q96JP5,P49427,O94822,Q9Y3I1,Q9NT62,Q5T4S7,Q7Z6Z7,Q9ULT8,Q9UDY8,Q9NR09,Q14258,O75925,O75592,P22681,Q5T447,Q6W2J9,Q14527 22 +Ribosomal small subunit binding 0.5678395118470235 1.2005395077871062 0.2299298784870878 1.0 0.4211856118409992 12 P41567,P15531,Q7Z478 3 +Phosphatidylinositol 3 phosphate binding 0.5452583773691267 1.1948253805083382 0.2321552618491849 1.0 0.4233594610744866 6 A1X283 1 +Dna polymerase activity 0.5565788737551124 1.194374744337858 0.232331411565267 1.0 0.4233594610744866 9 Q07864,Q15554,Q15185,P09884,P28340 5 +Glutathione disulfide oxidoreductase activity 0.5294678154790132 1.183318870941325 0.2366827966399403 1.0 0.429603930359475 3 P35754 1 +Zinc ion binding 0.251944288331595 1.1740185062164357 0.2403876131354658 1.0 0.4346307817261211 150 Q9UPT9,Q9UPP1,P09874,P04183,P10589,O95071,P38935,Q9UNI6,P26358,Q5F1R6,Q5TAX3,P07814,Q14839,P27708,Q8NB78,P29375,O94822,Q6GQQ9,Q5T4S7,Q07864,O00764,P26639,Q8IXJ6,Q13501,O75925,O75592,P29372,Q99707,Q9NY33,Q14527 30 +Nuclear import signal receptor activity 0.5603199262978487 1.1301339896038838 0.2584197694069521 1.0 0.4583169956148743 14 Q96P70,Q53FT3,Q92973,Q9Y5L0,O00629,Q9UI26,Q8TEX9,O00410 8 +Deacetylase activity 0.5364896757592825 1.1291889777502726 0.2588181224260069 1.0 0.4584402320989245 7 Q8IXJ6,Q9NX46,O94776,P10768 4 +Translation regulator activity 0.4344057928941678 1.1136155284854266 0.2654441617408016 1.0 0.4660316895046316 81 P00374,P41567,Q92905,Q13144,Q9ULC4,O00178,O15371,P13639,P49770,Q9BY44,P27635,Q7Z478,Q14240,Q92616,P26641,Q8NE71,Q05639,P41214,Q06787,Q04637,Q6PKG0,P63241,O60841,Q14152,P04818 25 +Dynein light chain binding 0.5102954341987347 1.1092944913695704 0.2673031607159521 1.0 0.4681163392437654 2 Q96EX3 1 +7sk snrna binding 0.5252261059657296 1.0916368804978471 0.2749927388811626 1.0 0.4797745657075603 6 Q7L2J0 1 +Cxcr chemokine receptor binding 0.5034318113995697 1.0739991347523867 0.2828230693493354 1.0 0.4849389405571631 2 P54577 1 +Gtpase inhibitor activity 0.5198318237465229 1.06396004981432 0.2873467977931885 1.0 0.4920902163681876 6 P46940,O43924 2 +Omega peptidase activity 0.5689033048531544 1.0227380569749014 0.3064317124104692 1.0 0.5159007332127947 31 Q70CQ2,Q9UPT9,P40818,Q93008,Q01804,Q96BN8,Q96RU2,Q96FW1,Q6GQQ9 9 +Histone methyltransferase activity h4 k20 specific 0.4955223880597105 1.00890470782487 0.3130203371851972 1.0 0.5244595553319289 3 Q6GMV2,Q96L73 2 +Cyclin binding 0.5326257076370865 0.9868792323504958 0.3237018463330434 1.0 0.5397142765997885 14 Q9UII4,Q9NYV4 2 +Histone deacetylase activity h3 k14 specific 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.5397142765997885 2 Q13547 1 +Ankyrin repeat binding 0.4849298716800817 0.9793361553740196 0.3274139115534007 1.0 0.5439987994105371 2 Q04206 1 +Protein phosphatase activator activity 0.4916351989665763 0.965406970312954 0.3343410116026608 1.0 0.5535289431996546 4 Q15257 1 +Nucleoside triphosphatase regulator activity 0.3914674998685642 0.9539336591425174 0.3401172243147397 1.0 0.5604295634689682 85 Q15436,Q14185,P21359,Q01968,Q13144,Q9HAD4,Q9P2J5,Q9P258,Q9Y6D5,Q6XZF7,Q9Y2L1,P49770,Q9NPQ8,Q9H8V3,Q8TC07,P49407,O00429,Q96N67,O95248,O43924,Q9P0V3,Q14155,O75592,P63167,Q92974,Q15042,Q15334,P46940,Q92538,Q86X10,Q9BTW9,O00401,O95373,O00410 34 +Wd40 repeat domain binding 0.4884402809724389 0.9492056413724616 0.3425160329166892 1.0 0.5630511201484254 4 Q99459 1 +Cysteine type endopeptidase activity 0.5514714592576825 0.947181432210201 0.3435463351871355 1.0 0.564079612780762 27 Q70CQ2,P55212,Q86UV5,P42574,Q93008,Q9Y4P1,P40818,Q14674,Q96RU2,Q9UDY8 10 +G quadruplex dna binding 0.4940164620922851 0.932536169392464 0.3510595034397399 1.0 0.5737127172274296 6 P22392,Q8IZH2,P54132 3 +Ubiquitin like protein specific protease activity 0.5522447813456104 0.9251270848173692 0.3548998059037718 1.0 0.5786319642454477 37 Q70CQ2,Q9UPT9,Q86UV5,Q9Y4P1,Q93008,P40818,Q01804,Q96BN8,Q96RU2,Q96FW1,Q6P2Q9,Q6GQQ9 12 +Fatty acid transmembrane transporter activity 0.472993136377194 0.9187749788035168 0.3582132824566346 1.0 0.5820960368583417 2 O14975 1 +Catalytic activity acting on a trna 0.4888325619451197 0.9147977274951316 0.360297828044934 1.0 0.5833393406441789 66 Q96FX7,O15091,O43776,Q9P2J5,O60294,Q9UBP6,P57081,Q9UET6,P07814,O75818,P41252,Q6P1R4,P23381,P54136,Q8TEA1,Q08J23,P26640,Q9BV44,Q9BQ52,Q9H974,P26639,Q9BTE6,Q99575,P78346,O95707,Q7Z2T5,Q7Z4G4,P47897,P49589,Q9NSD9,Q96Q11 31 +Cytoskeletal anchor activity 0.4932370082415404 0.9085331619411776 0.3635966013402825 1.0 0.5846063001941797 7 P78559 1 +Muscle alpha actinin binding 0.474925373134338 0.9044188384659332 0.3657733527104425 1.0 0.5860782226188009 3 Q9NR12,Q96HC4 2 +Alpha actinin binding 0.474925373134338 0.9044188384659332 0.3657733527104425 1.0 0.5860782226188009 3 Q9NR12,Q96HC4 2 +Solute sodium symporter activity 0.4673231871083192 0.8901902801917657 0.3733637228628463 1.0 0.5961844555221166 2 P55011 1 +Deoxyribonuclease activity 0.5221622445120788 0.8787928855318977 0.3795135844768198 1.0 0.6032405208217637 18 P15531,P27695,Q07864,P28340 4 +Metal dependent deubiquitinase activity 0.4858947553031328 0.8717060350594669 0.3833687670642278 1.0 0.6079818672213124 7 O00487,Q6P2Q9,Q7L5N1,Q92905 4 +5 deoxyribose 5 phosphate lyase activity 0.4613548194568633 0.8602484087036858 0.3896521251874953 1.0 0.6153332568778829 2 P13010 1 +Actinin binding 0.4752090800477764 0.8600346941739713 0.3897699180940965 1.0 0.6153332568778829 5 Q16527,Q9NR12,Q96HC4,Q04206 4 +Transferase activity transferring one carbon groups 0.472308020984973 0.8553766583431516 0.3923426613865612 1.0 0.6159679629613469 68 Q96FX7,P04818,Q86W50,P26358,O60294,Q8NCA5,Q9BV86,Q9H2P9,Q9UBP6,P57081,Q9UET6,O43709,P46087,P27708,Q86TU7,Q8TEA1,Q08J23,Q99873,Q96P11,Q14353,Q8N1G2,Q8IY81,O60678,Q7Z2T5,O14744,Q7L2J0,Q15047,Q7Z4G4,P31939,Q99707,Q8WVM0,Q6UXN9 32 +Hydrolase activity acting on acid anhydrides 0.2098344083392623 0.844450786478102 0.3984175529592897 1.0 0.6219418463888576 283 P46063,P51532,Q12873,P38935,Q96DE0,Q9GZR7,Q6P158,Q0VDF9,Q9Y6B6,Q92499,O60942,Q96QE3,Q7Z478,Q9Y295,Q9H4L7,Q8IX18,Q9HCK8,Q05639,Q14147,P60953,P35251,Q7Z7L1,Q86WJ1,Q14527,P54277,Q9Y5Y2,P33992,O00178,P13639,Q9Y496,Q7L014,Q92620,Q9HCE1,P36915,O00429,P33993,Q14562,O60231,O14646,Q9BW19,O60841,Q9Y450,Q96C86,Q2NL82,Q8IY37,P84085,O43933,P54132,Q2NKX8,Q9P2D1,Q96GQ7,Q99661,Q15058,Q9BUF5,Q14692,Q13885,Q14839,O75348,Q9NUL7,Q8N3C0,P61586,P33316,P18074,P04350,Q9Y3D8,Q9H2U2,Q92614,Q9ULI0,Q96Q89,Q9NTJ3,Q14240,O60333,Q15382,Q6PL18,Q15019,O14981,P26196,P50570,Q9BVQ7,Q5T9A4,Q9H6S0,Q9UKK9 82 +Dna binding transcription repressor activity 0.4947334991322034 0.8430144519321351 0.3992203612542755 1.0 0.6220379022800891 11 Q96KM6,Q9Y2X9,P10589,P85037 4 +O methyltransferase activity 0.4833531649082619 0.8398511184198856 0.4009918677996547 1.0 0.6231690788324623 8 Q8N1G2,Q9UET6,Q7L2J0 3 +Rna stem loop binding 0.4857031136387607 0.8330637552286468 0.4048087735375132 1.0 0.6282883787505024 9 Q86W50,Q06787,P07814 3 +Damaged dna binding 0.5304446844980409 0.8307503519215245 0.406114675079755 1.0 0.6283283652177343 28 P52701,P09429,P27695,P35244,P20585,P28340,P18074 7 +Phosphatidylinositol bisphosphate binding 0.5119279997382689 0.8270627175107782 0.4082015143695914 1.0 0.630856885843914 18 O43795,Q9BTX7,Q9Y484,Q8TEW0,Q13045,Q92538,A1X283,P07737,Q9Y5X3,O60493,Q9BPX3 11 +Atp dependent activity acting on dna 0.5028390953490245 0.8225137613761462 0.4107845578245204 1.0 0.6327443907263883 58 P46063,P54132,P51532,P38935,Q12873,Q9P2D1,P33992,P52701,O14981,Q14839,Q8N3C0,P18074,Q92499,Q96QE3,Q92614,Q9Y620,Q9H4L7,P33993,Q9UNY4,Q9HCK8,Q12830,O14646,P35251,Q86WJ1,Q14527 25 +Long chain fatty acid transporter activity 0.4619289340101562 0.8163606530215882 0.4142938937988196 1.0 0.636925912407498 4 P28288,O14975,Q6P1M0 3 +Ephrin receptor binding 0.4644873074391301 0.8068410769812393 0.4197580498995672 1.0 0.6430139797362601 5 P22681 1 +Isopeptidase activity 0.4787780627014051 0.79882888155175 0.4243896412081938 1.0 0.6479727928195205 9 Q7L5N1,Q92905,Q9H4L4,O00487,Q6P2Q9 5 +Aminoacyl trna editing activity 0.481712460645357 0.7956122935778669 0.4262574188922983 1.0 0.6501125185293916 10 Q9BTE6,P26640,P41252 3 +Translation regulator activity nucleic acid binding 0.4728339992836854 0.77558357491686 0.43799490155989 1.0 0.6651033690353886 65 P00374,P41567,Q92905,Q13144,Q9ULC4,O00178,O15371,P13639,P49770,Q9BY44,Q7Z478,O43432,Q14240,Q92616,P26641,Q8NE71,Q05639,P41214,Q04637,Q6PKG0,P63241,O60841,Q14152,P04818 24 +Dna polymerase binding 0.4763251045066987 0.7691886064665527 0.4417813531510848 1.0 0.6680570825656351 10 P09429,Q9NVI1,P51532 3 +S adenosylmethionine dependent methyltransferase activity 0.5059320035735884 0.7318883946424405 0.4642366902051122 1.0 0.6936183774340048 50 Q96FX7,Q86W50,P26358,Q9H2P9,Q9UBP6,P57081,Q9UET6,O43709,P46087,Q86TU7,Q8TEA1,Q08J23,Q99873,Q96P11,Q14353,Q8N1G2,Q8IY81,O60678,Q7Z2T5,O14744,Q7L2J0,Q15047,Q7Z4G4,Q8WVM0,Q6UXN9 25 +Sh3 domain binding 0.4970610669327533 0.7299552088297585 0.465417563868107 1.0 0.6946382056018643 20 P22681,O15357,Q14185,P50570,P40818,Q9NZQ3,Q9Y5K6 7 +Cysteine type peptidase activity 0.502271691440269 0.7206888680480003 0.4711009629638893 1.0 0.7016183144996386 51 Q70CQ2,Q9UPT9,P17655,Q9UDY8,P55212,Q86UV5,P42574,Q93008,Q9Y4P1,P40818,Q14674,Q01804,Q96BN8,Q96RU2,Q96FW1,Q6P2Q9,Q6GQQ9 17 +Cytoskeletal motor activity 0.5077312422644205 0.7147504809907302 0.4747632386509837 1.0 0.7055649836668137 28 Q9UM54,O43795,Q15058,O94832,P35580,Q9BW19,P35579,Q13526,Q9Y496,Q14204,Q96Q89,O00139,Q99661,O60333 14 +Transcription regulator activity 0.2161731113522494 0.6987362915836527 0.4847168492458711 1.0 0.7157789066194324 190 O75569,Q15648,Q9UPT9,P61457,Q9UPP1,Q9UIV1,O00170,Q7Z4V5,Q92905,P10589,P51532,Q6P1K2,Q9Y4A5,Q9UER7,Q9H1B7,Q92600,Q9UKL3,Q9Y5V3,O00625,Q9ULK4,O14981,P40763,Q86TU7,Q01844,P29375,Q92499,Q9BQ70,Q92908,P17096,P49407,O60244,O14744,Q14258,Q16512,O75925,O75182,P51858,P27695,P09429,P22392,Q9Y6J9,Q8WVM0,Q99459,Q96KM6,Q9H582,P85037,Q6W2J9,Q9Y2X0,Q8IWI9,Q8IUF8,Q9Y2X9,Q7LBC6,Q99816 53 +7s rna binding 0.4503092917415072 0.6975073178345744 0.4854853613688776 1.0 0.7161551256594872 7 O76094,Q9UHB9 2 +Trna binding 0.5026123497594094 0.6824520454371686 0.4949531557482092 1.0 0.7278108640432528 46 Q2VPK5,O43592,P38935,Q9UBP6,Q9HAV4,O95163,P41252,Q9BY44,P54136,Q8TEA1,Q08J23,O60524,P26639,Q9H9T3,Q7Z2T5,Q7Z4G4,P49589,Q7Z7L1,Q96Q11 19 +Microtubule motor activity 0.4799657276798608 0.6701912495426247 0.5027358813381575 1.0 0.7338364592517189 18 Q15058,Q9BW19,Q96Q89,Q14204,Q9Y496,O00139,Q99661,O60333 8 +Sh2 domain binding 0.4551256064551114 0.6672772688990064 0.5045950431776798 1.0 0.7357798014536461 10 Q13501,A1X283,Q96T51,O15357 4 +Phosphatase activator activity 0.4389815384100873 0.6626892702596834 0.5075295831029814 1.0 0.738596773065155 6 Q15257 1 +Dna secondary structure binding 0.4528788716369442 0.6566961087291863 0.5113763370195259 1.0 0.7433353637176424 10 P17096,P52701 2 +Phosphoprotein phosphatase activity 0.4989402440951 0.6406442713649962 0.5217538291399868 1.0 0.7521456440756376 39 Q99504,Q8TF05,Q08209,P62136,Q13614,Q12923,Q9UNI6,P51452,Q99956,Q9ULE6,Q06124,P30307,O60942,Q9H2U2,Q15257,O95248,Q13555,Q14738,Q8NCE2,O00743 20 +Histone kinase activity 0.4417378964127983 0.6215538321418577 0.5342352867169899 1.0 0.7632286283611934 9 Q99986,O14965 2 +K48 linked polyubiquitin modification dependent protein binding 0.4297997731562046 0.619831494820026 0.535368731137797 1.0 0.7638730923296716 6 Q8TAT6,Q96EP0 2 +Tau protein binding 0.4702817453647144 0.6128567958118097 0.539971032670254 1.0 0.769651962722223 19 Q14203,P78559,P49841,Q13464,O75116,Q7KZI7,Q00535 7 +Gtp dependent protein binding 0.4243398291521855 0.594738940590827 0.552017987923014 1.0 0.7828210327209375 6 O00203,P60953,O00429,P61020 4 +Glutathione oxidoreductase activity 0.4149787803470544 0.5919628809598511 0.5538754448543013 1.0 0.7846568802102601 4 Q16881 1 +Kinesin binding 0.438232424449675 0.5889235710021125 0.5559125449955078 1.0 0.7859453222350283 10 Q96EK5,Q15334,O60333 3 +Rna polymerase ii activity 0.4010743061772542 0.5707107348132711 0.5681957408539582 1.0 0.8008471159811338 2 P30876 1 +Hexokinase activity 0.4001790510295411 0.5666525199719206 0.5709502850120776 1.0 0.8008471159811338 2 P52789 1 +Endoribonuclease activity 0.4688198147927087 0.5658027904236803 0.5715278493642231 1.0 0.8008471159811338 23 Q96DE0,O75818,P27695,O15091 4 +Adenylyltransferase activity 0.4255633018990236 0.564817656937034 0.5721977959233926 1.0 0.8008471159811338 8 P51003,Q9NVV4,Q8NFF5,Q96Q11,O43252 5 +Eukaryotic initiation factor 4e binding 0.4082585798071145 0.5614816709896941 0.5744692219294474 1.0 0.8024149252200898 4 Q6PKG0 1 +Translation initiation factor activity 0.4796756096853879 0.5445209053436141 0.5860830665465453 1.0 0.814556126386724 39 Q9ULC4,P41567,O15371,P41214,Q04637,Q92905,Q7Z478,P49770,Q13144,Q9BY44,O60841,Q14152,Q14240 13 +Dna helicase activity 0.478236366641228 0.5379130707995199 0.5906370641620611 1.0 0.8169022030982916 40 O14646,Q14839,P46063,P54132,Q9Y620,Q8N3C0,Q9H4L7,P38935,Q12873,Q86WJ1,Q9P2D1,P33993,P18074,Q9HCK8,P33992 15 +5s rrna binding 0.4156539045830234 0.5378253397042965 0.5906976362024106 1.0 0.8169022030982916 7 P39023 1 +N acetyltransferase activity 0.4430573694899913 0.5378202322208805 0.5907011626420933 1.0 0.8169022030982916 15 Q9UPT9,P49407 2 +Carbon nitrogen lyase activity 0.4068190869702297 0.5353415704819813 0.5924136856500022 1.0 0.818458550838556 5 O75592 1 +Protein phosphorylated amino acid binding 0.4316767955620022 0.5289391888917269 0.5968476353893111 1.0 0.8229531194190897 12 Q06124,P28482,P22681,P46109,Q13526 5 +Peptide hormone receptor binding 0.395780577055533 0.526146714633651 0.5987862733872034 1.0 0.8239961155989748 3 Q06124 1 +Hormone receptor binding 0.395780577055533 0.526146714633651 0.5987862733872034 1.0 0.8239961155989748 3 Q06124 1 +Ubiquitin like protein ligase activity 0.4678148709902421 0.5230191288284289 0.6009609416493549 1.0 0.8261731288552275 50 O75925,Q96EP0,O75592,Q5T4S7,Q7Z6Z7,P22681,O95071,Q14527,Q9ULT8,O94822,Q9UII4,Q9Y314,Q15386,Q14258 14 +Atp dependent activity acting on rna 0.4599464018079345 0.505935084455601 0.6129022216971034 1.0 0.8392786807915149 53 Q9HCE1,Q9H6S0,O60231,Q14147,Q8IY37,Q6P158,P26196,Q9NUL7,Q7Z478,Q8IX18,P38935,Q7L014,Q14240,Q9GZR7,Q15477,Q92499 16 +Nucleotide diphosphatase activity 0.3892537313432933 0.4976310167970705 0.618744137881049 1.0 0.8464468382788836 3 Q9BY32,Q9BW91 2 +Transcription coregulator activity 0.2138606883810572 0.4774144638015622 0.6330670167309431 1.0 0.8609711427540826 151 Q15648,Q9UPT9,P61457,Q9UPP1,Q9UIV1,O00170,Q7Z4V5,Q92905,P51532,Q6P1K2,Q9Y4A5,Q9UER7,Q92600,Q9H1B7,Q9UKL3,Q9Y5V3,Q9ULK4,O14981,Q86TU7,Q01844,P29375,Q92499,Q9BQ70,P17096,P49407,Q14258,Q16512,O75925,O75182,P09429,P27695,P22392,Q9Y6J9,Q6W2J9,Q9Y2X0,Q8IUF8,Q7LBC6,Q99816 38 +Phosphatidylcholine binding 0.4038484717734936 0.4702533690829854 0.6381740086387044 1.0 0.8662264537900234 8 Q00169 1 +Sirna binding 0.3890643909245073 0.45890055566626 0.6463055797256874 1.0 0.8764104845696578 5 Q06787 1 +Ligand gated cation channel activity 0.3751119068934641 0.457055449448023 0.6476311906876613 1.0 0.8765027959403882 2 Q96ER9 1 +U6 snrna binding 0.4064945870291561 0.4507021811216086 0.6522042101476389 1.0 0.8801284307316636 10 Q15020,Q86W50,Q4G0J3,P63241 4 +Glucose binding 0.3910973424091808 0.4495713304375046 0.653019564251127 1.0 0.8803764725010358 6 P06737,P11413,P13807 3 +C3hc4 type ring finger domain binding 0.3770149253731414 0.4457318496182351 0.6557909551876742 1.0 0.8832585425426259 3 P31689,P0DMV9 2 +Double stranded methylated dna binding 0.3764179104477683 0.4432560838269553 0.6575805169385738 1.0 0.8848139388150308 3 O75367,Q9UIS9 2 +Translation factor activity rna binding 0.4416980860204507 0.4402491370669292 0.6597566747678965 1.0 0.8868860218191396 56 P41567,Q92905,Q13144,Q9ULC4,O00178,O15371,P13639,P49770,Q9BY44,Q7Z478,O43432,Q14240,Q92616,P26641,Q8NE71,Q05639,P41214,Q04637,P63241,O60841,Q14152 21 +Translation initiation factor binding 0.4259768823055163 0.4294771627433282 0.6675760099713104 1.0 0.8951639160201736 18 Q6PKG0,Q13144,Q06787,P62847 4 +Intramolecular transferase activity phosphotransferases 0.3816650047050071 0.4283671905615684 0.6683838077240445 1.0 0.8951639160201736 5 O95394 1 +Mdm2 mdm4 family protein binding 0.3858620470205178 0.428094672918515 0.6685821950152819 1.0 0.8951639160201736 6 P62841,P60866,P61289 3 +Lim domain binding 0.3679498657117295 0.4273486609445349 0.6691253949017366 1.0 0.8951639160201736 2 Q9Y490 1 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines 0.3888175225077587 0.4240652368632077 0.6715182371426156 1.0 0.8975037608598334 7 Q01433 1 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides 0.3835484618840836 0.4187399458084132 0.675406198594305 1.0 0.9009724792731684 6 Q9BPU6 1 +Retinoic acid receptor binding 0.3846078997205033 0.4071923024620171 0.6838667547066954 1.0 0.907987005770965 7 P17096,A5YKK6 2 +Long chain fatty acid coa ligase activity 0.3791455034359134 0.4011758736110449 0.6882906423472179 1.0 0.9089006338440684 6 O14975,Q6P1M0,P33121,O95573,Q96CM8 5 +3 5 exonuclease activity 0.4387991624677339 0.3987761550494471 0.69005814833104 1.0 0.9094518137956694 28 P27695,Q07864,A5YKK6,Q9Y2L1,Q9GZR2,Q9H9L3,P28340 7 +Ligase activity forming carbon oxygen bonds 0.4448077637900272 0.3960818805469124 0.6920446247934062 1.0 0.9101039688320832 34 P47897,P49589,P26639,P07814,Q9BTE6,P41252,O43776,P23381,P54136,Q9NSD9,Q9P2J5,P26640 12 +Protein serine threonine phosphatase activity 0.4251007960917479 0.3876294430431693 0.6982902769051567 1.0 0.9165881789131716 22 Q13555,Q9H2U2,P51452,Q08209,Q99956,P62136,Q9UNI6,Q8NCE2,O00743 9 +Fatty acid ligase activity 0.3792588164973047 0.3861745958208478 0.6993673668180984 1.0 0.916596868266392 7 O14975,Q6P1M0,P33121,Q4G176,O95573,Q96CM8 6 +Mirna binding 0.4081220379060005 0.380342196280431 0.7036914167173116 1.0 0.9210759013182463 16 Q8IWR0,P67809 2 +Gamma tubulin binding 0.380992407133706 0.3780883495491088 0.7053649627854475 1.0 0.922115132350372 8 Q16512,Q9BSJ2,Q96CW5 3 +Phosphoric ester hydrolase activity 0.3793527958731219 0.3711035945706148 0.7105603738196049 1.0 0.926171428306224 73 Q9NUW8,Q9NZC3,O15357,Q99504,Q9Y217,Q08209,Q8TF05,P62136,Q13614,Q01968,Q12923,Q9UNI6,Q9BRJ7,Q70Z53,Q96DE0,Q9Y3Z3,P51452,Q99956,Q9ULE6,Q5TFE4,Q06124,O60942,P30307,Q9H2U2,Q15257,O95248,Q9H0R4,P27695,Q13555,Q08623,Q14738,Q8NCE2,O00743 33 +Nuclease activity 0.3830491608048034 0.3705585676455957 0.7109663465490412 1.0 0.926171428306224 72 Q9UIV1,P27695,Q07864,P15531,Q8IZH2,A5YKK6,O75818,Q99575,O15091,Q9Y2L1,Q9GZR2,Q9H9L3,P28340,Q96C86,Q96DE0,Q66K74 16 +Ceramide binding 0.362197670946546 0.3686937209877347 0.712356029471384 1.0 0.926171428306224 4 Q9NZJ7,P45880,P21796 3 +Microtubule binding 0.3623747907049317 0.3674792342956234 0.7132615786235006 1.0 0.926171428306224 77 Q9UHD1,Q15398,O43670,O15344,Q00535,Q9BSJ2,Q9P258,Q6NUK4,O00139,Q99661,Q14203,Q15058,Q9UPN3,Q9Y496,Q9UH99,P50570,Q9P1Y5,O00429,Q9Y295,Q96CW5,Q96Q89,Q9BT25,O60333,P43034,P78559,Q14008,Q06787,Q9BW19,P29372,Q92974,Q7Z4H7,Q7Z460,P53350,P46821,Q9BPU6,Q9H6H4,Q66K74 37 +Poly g binding 0.369403283885397 0.3634771936563374 0.7162484464765357 1.0 0.926171428306224 6 Q86TB9 1 +Pentosyltransferase activity 0.4089236436716152 0.3623728194743083 0.7170734481588033 1.0 0.926171428306224 18 P00492,P07741,Q9H974,P09874,P43490,Q8IXJ6,P11172,Q13126 8 +Phosphatidylinositol 4 5 bisphosphate binding 0.3871510813672819 0.3604514103229501 0.7185095867889504 1.0 0.926171428306224 11 O43795,Q8TEW0,Q13045,P07737,Q9BPX3 5 +Ubiquitination like modification dependent protein binding 0.3642678749158087 0.3600692743877769 0.7187953293534874 1.0 0.926171428306224 5 P14735,Q9UER7,Q99543 3 +Cytokine receptor binding 0.4213228773061591 0.3570532266158011 0.7210519592890512 1.0 0.9281130482446328 24 P30046,P42574,O43776,P62942,Q9Y5K6,Q9UKL3 6 +U3 snorna binding 0.3811212318689992 0.3509575119452753 0.7256202239269922 1.0 0.9308134152944276 10 Q2NL82,P78527 2 +Methylated histone binding 0.4239489566210722 0.346642237107099 0.7288601104511818 1.0 0.932138526577016 27 Q9UPP1,O14646,Q7Z4V5,P29375,P42695,Q9HCK8 6 +Insulin receptor binding 0.3634398558547662 0.3412348884907689 0.7329267605499818 1.0 0.934903191717672 6 O14654 1 +Tumor necrosis factor receptor superfamily binding 0.3711423091235349 0.3410926275175426 0.7330338511817902 1.0 0.934903191717672 8 P42574 1 +Ribonucleoprotein complex binding 0.2918885348151495 0.336808412084867 0.7362613312950688 1.0 0.9364491750231076 90 P41567,P62314,P38935,Q96D46,P13639,Q9HAV4,P15531,O76094,Q9BY44,Q86UK7,O94822,Q9UHB9,Q8IWS0,O60524,P57678,P42345,Q7Z478,O60678,Q92616,P09012,Q14008,Q06787,Q6PKG0,P63241,P60059 25 +Guanyl nucleotide exchange factor activity 0.4314313419966087 0.331336484209971 0.7403903358009454 1.0 0.9399855447236044 40 Q9H8V3,O75592,Q14185,Q92974,Q15042,Q96N67,Q9Y2L1,Q6XZF7,Q13144,P49770,Q9NPQ8,O95248,Q9HAD4,Q92538,Q9P258,Q9Y6D5 16 +Molecular function inhibitor activity 0.3688930720799578 0.3196179264950068 0.7492579832961874 1.0 0.949514207922623 9 P62942,Q9NWR8 2 +Rna polymerase i transcription regulatory region sequence specific dna binding 0.3479299194369575 0.3160123960579198 0.7519930992225814 1.0 0.9521147868449396 4 P51532 1 +N methyltransferase activity 0.4115392784526099 0.3138732980125326 0.7536172713781286 1.0 0.9533053323966528 25 Q86W50,Q86TU7,O60678,Q7Z2T5,Q7Z4G4,O14744,Q99873,Q15047,Q6UXN9 9 +Polyubiquitin modification dependent protein binding 0.3949001211827385 0.3021213788700583 0.7625595355219013 1.0 0.9579359892383248 19 Q96EP0,Q04323,Q96S82,Q8TAT6,P46379,P35573,Q13501,Q6P2Q9,Q6GQQ9 9 +Protein domain specific binding 0.1933307788808052 0.2952742710235356 0.767784369505164 1.0 0.9616275032256952 183 P36507,Q15648,P23921,O15357,Q14185,O00170,A5YKK6,Q6P1K2,A1X283,Q9P258,Q92600,Q9Y5K6,Q9HCM4,P20645,P17612,O76094,P26196,P20248,P22059,P67870,P78527,Q9UHB9,P30307,O94832,Q96T51,P50570,O94973,Q00610,Q9NZQ3,Q96Q89,Q9Y613,P31689,Q9BPX3,Q9UQB8,Q13501,Q9HCK8,P63167,P22681,P35579,P60953,P40818,Q99459,P35251,P46940,Q15334 45 +Lysine acetylated histone binding 0.3727420149318439 0.2856167436464876 0.7751716778780016 1.0 0.9682187114947411 13 P51532,Q14997,P25440 3 +Endonuclease activity 0.4171937442043415 0.2843258270573738 0.7761606953977382 1.0 0.9682187114947411 36 P27695,O75818,Q99575,O15091,Q9Y2L1,Q9GZR2,Q96DE0 7 +Dynein complex binding 0.3509475765828139 0.2836044050713834 0.7767135609118676 1.0 0.9682187114947411 7 Q06787,P43034 2 +Tbp class protein binding 0.3569553907491354 0.2786830606776185 0.7804880633239546 1.0 0.9682187114947411 9 Q86VP6,O75155 2 +Regulatory rna binding 0.3879070569639963 0.2784237237561445 0.7806871102726607 1.0 0.9682187114947411 19 Q8IWR0,P67809 2 +Phosphoric diester hydrolase activity 0.3631893103769287 0.2759518128511944 0.7825850773994751 1.0 0.9697098647954384 11 P27695 1 +Bh3 domain binding 0.326171292151598 0.2718584588634312 0.7857308536171448 1.0 0.9713381965534724 2 P63244 1 +Bh domain binding 0.326171292151598 0.2718584588634312 0.7857308536171448 1.0 0.9713381965534724 2 P63244 1 +N acyltransferase activity 0.382442771273819 0.2606320380443759 0.7943762805600483 1.0 0.9759577154144876 19 Q9UPT9,Q14CX7,P49407,P30419,Q9GZZ1 5 +Gtpase activating protein binding 0.3357592045967291 0.2603051343102097 0.7946284124787972 1.0 0.9759577154144876 5 Q14C86,Q13526,P07437 3 +Death domain binding 0.3262686567164237 0.2575879184549029 0.7967249548168631 1.0 0.9768114221765234 3 Q13546,P63244 2 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.3327340569666407 0.2507021813813752 0.8020443740337198 1.0 0.9797560038787424 5 P98170,Q15418 2 +Poly a specific ribonuclease activity 0.3375671159228496 0.2407437184980515 0.8097537528162295 1.0 0.9824862461223745 7 A5YKK6 1 +Phosphatase activity 0.3871841622977511 0.2399047890577751 0.8104040681339095 1.0 0.9824862461223745 61 O15357,Q99504,Q9Y217,Q8TF05,Q08209,P62136,Q13614,Q01968,Q12923,Q9UNI6,Q70Z53,Q96DE0,P51452,Q99956,Q9ULE6,Q5TFE4,Q06124,O60942,P30307,Q9H2U2,Q15257,O95248,Q9H0R4,Q13555,Q08623,Q14738,Q8NCE2,O00743 28 +Phosphotransferase activity for other substituted phosphate groups 0.3292074720081361 0.2397605220164244 0.8105159132286446 1.0 0.9824862461223745 5 O96017 1 +Signal recognition particle binding 0.3265205174653605 0.2316092077707076 0.8168415551959436 1.0 0.987302133758988 5 O76094 1 +Spectrin binding 0.3343403305819101 0.2309909246460069 0.8173218524805397 1.0 0.987302133758988 7 Q9Y496 1 +Quaternary ammonium group binding 0.349321484370879 0.2225368829449336 0.8238959645557093 1.0 0.9918470611873588 12 Q00169 1 +Ionotropic glutamate receptor binding 0.3268521586140912 0.2203312975253407 0.8256131471075854 1.0 0.993015295140616 6 Q13501 1 +Myosin binding 0.3513988288514059 0.2191061644198763 0.8265673489291365 1.0 0.9933059348338072 13 P27695,Q9Y6D5 2 +Non membrane spanning protein tyrosine kinase activity 0.315318005374729 0.2112058596491255 0.8327266385504253 1.0 0.9987731374292276 4 P19525,P41240,Q9UIG0 3 +Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.390563419079934 0.2105143479140403 0.8332662545410272 1.0 0.9987731374292276 32 P27695,Q07864,Q8IZH2,A5YKK6,Q9Y2L1,Q9H9L3,P28340 7 +Ubiquitin binding 0.3852604148322623 0.2071021726567286 0.8359300653483746 1.0 1.0 29 Q96EP0,Q9Y263,Q99816,Q8IXJ6,O95071,Q9H4L7,Q13501,Q9Y3I1 8 +Mrna 5 utr binding 0.3697246703389758 0.2010755302603257 0.8406395152454786 1.0 1.0 22 Q06787,P61247,P62081,P62277,Q6PKG0,P61254,P46777 7 +Intramolecular oxidoreductase activity interconverting aldoses and ketoses 0.3111376530307444 0.1994823266376554 0.8418854668356248 1.0 1.0 4 P46926,P06744,P60174 3 +Histone binding 0.2679776932884744 0.1839679402780032 0.8540386055804352 1.0 1.0 90 Q9UPP1,O75607,Q7Z4V5,P51532,Q9UER7,P42695,P52701,Q15021,P25440,Q14997,Q8NB78,Q08945,P29375,Q8IWS0,Q96P70,Q15020,Q9HCK8,Q16512,Q06787,O14646,A3KN83,Q9UIF9 22 +Rna polymerase ii general transcription initiation factor activity 0.3149177381571335 0.1772924944052758 0.8592786460052559 1.0 1.0 7 Q9Y6J9 1 +Chromatin binding 0.1835360573724742 0.1753282609232632 0.8608217066884807 1.0 1.0 188 Q15648,Q9UPP1,P67809,O75607,P51532,P28340,P26358,Q9H3P2,Q9P2D1,Q9NRZ9,P52701,P25440,Q96L91,Q14839,P40763,Q8NB78,Q08945,P29375,P67870,Q92499,Q92908,P17096,Q07864,Q8IXJ6,Q9H4L7,O14802,Q9NTJ3,Q9HCK8,Q16512,O75182,Q15003,P27695,Q06787,A3KN83,Q9BTE3,Q7LBC6,Q6UXN9 37 +Aldehyde lyase activity 0.3055555555555432 0.1736896464384497 0.8621093747907 1.0 1.0 5 P04075,O95470,Q9H993,P09972 4 +Methyl cpg binding 0.3276688059735546 0.1731616505996655 0.8625243666114049 1.0 1.0 11 Q99873,P26358,Q9Y3Y2 3 +Rna polymerase activity 0.3565064664531857 0.1725415806139693 0.8630117748982196 1.0 1.0 21 O14802,Q9BWH6 2 +Protein membrane adaptor activity 0.3239290288738574 0.1724478368509937 0.8630854670694779 1.0 1.0 10 Q9UH99 1 +S100 protein binding 0.3166161019646147 0.1721544212011213 0.8633161294322664 1.0 1.0 8 P46940 1 +Histone methyltransferase activity h3 k4 specific 0.3077272977726237 0.1689019839472614 0.8658737386556579 1.0 1.0 6 Q6UXN9 1 +Exonuclease activity 0.3795107883846189 0.1622344579290033 0.8711212257180532 1.0 1.0 40 P27695,Q07864,Q8IZH2,A5YKK6,Q9Y2L1,Q9GZR2,Q9H9L3,P28340,Q96C86 9 +Pre mrna 3 splice site binding 0.2855863921217597 0.1561700481900905 0.8758989851105448 1.0 1.0 2 Q01081 1 +Dna replication origin binding 0.3267455924529504 0.1479294191404401 0.8823984705103443 1.0 1.0 14 O43913,Q9UBD5,P33993,Q99741,P33992 5 +Gtpase activator activity 0.3746730401578906 0.1479222331352408 0.8824041417233823 1.0 1.0 43 Q9H8V3,Q8TC07,Q9BTW9,Q15436,Q14185,P49407,O00429,P21359,Q01968,Q15042,P46940,Q86X10,Q9P2J5,Q15334 14 +Ribonuclease activity 0.3705925471489173 0.1415971523643974 0.8873982163532268 1.0 1.0 50 Q9UIV1,P27695,Q8IZH2,A5YKK6,O75818,Q99575,O15091,Q9Y2L1,Q9H9L3,Q96C86,Q96DE0 11 +Modification dependent protein binding 0.35739991126879 0.1409951082634312 0.8878738067792866 1.0 1.0 61 Q96EP0,P52701,Q9UPP1,Q96S82,O14646,P25440,Q06787,Q7Z4V5,P51532,Q14997,Q9UIF9,Q9HCK8,P35573,P29375,Q13501,Q9UER7,Q6GQQ9,P42695 18 +Glutamate receptor binding 0.2990108583443597 0.1398947743131738 0.8887431301819455 1.0 1.0 7 Q13501 1 +Phosphatidylinositol phosphate binding 0.3599638397913012 0.1392043663158788 0.889288658278423 1.0 1.0 30 Q7Z3T8,Q9BTX7,Q13045,P22059,Q8TEW0,P46940,A1X283,Q92538,Q9Y5X3,Q9P2R3,Q9BPX3 11 +Symporter activity 0.3032664324773365 0.1333550262157082 0.8939126115324751 1.0 1.0 9 Q9Y666,P53985 2 +Cargo adaptor activity 0.2964680141529212 0.1268454387353416 0.8990627312654365 1.0 1.0 8 O94973,O95782,Q9BXS5 3 +Scaffold protein binding 0.3376566318587704 0.1249516695834094 0.9005618124559602 1.0 1.0 22 O15111,Q9Y4P1,Q96RD7,Q9UQB8,Q8IWS0 5 +Protein disulfide reductase nad p activity 0.2838897305342118 0.1168986745962629 0.9069403484720642 1.0 1.0 6 Q16881 1 +Voltage gated channel activity 0.2954100507880655 0.1111880254344219 0.9114672470716356 1.0 1.0 10 Q9Y696,Q00535,P21796,O00299 4 +Signaling adaptor activity 0.3189749303046712 0.1088809227832499 0.9132969380882894 1.0 1.0 18 Q06124,P36507,Q96T76,P46109,P46940,P40763,O60271,P63244 8 +Ubiquitin like protein binding 0.3521363462130297 0.1080059660817047 0.9139909596485604 1.0 1.0 36 Q96EP0,Q9Y263,Q99816,Q8IXJ6,O95071,Q9H4L7,Q13501,Q9Y3I1,Q9UKL3 9 +Nucleotidyltransferase activity 0.354313123998103 0.1060230855441687 0.9155640358015124 1.0 1.0 51 O96017,Q2VPK5,Q5TAX3,O60942,Q07864,Q9NW08,P51003,P28340,O14802,Q96IJ6,Q9BUI4,Q9BWH6,Q9UKK9 13 +Centromeric dna binding 0.267243953418922 0.1014808265847363 0.9191687771465322 1.0 1.0 4 O43264,Q99661,P43246 3 +Kinase regulator activity 0.3504170315359125 0.09944985249207 0.9207811023479076 1.0 1.0 52 P47897,O95067,Q9UDY8,P42574,Q9H9T3,P20248,P42771,Q7KZI7,O75909,P14635,P46940,Q92616,P67870,Q9UER7 14 +Peptidase activator activity 0.2889563062625886 0.0943825245597893 0.9248052972128852 1.0 1.0 11 Q14997,Q9UKL3 2 +2 oxoglutarate dependent dioxygenase activity 0.3119561591048114 0.0926009886959775 0.9262205582591794 1.0 1.0 19 P29375,Q7LBC6,Q6P6C2 3 +Aminopeptidase activity 0.3005020429987097 0.0924352603607481 0.9263522256212208 1.0 1.0 15 P29144,P50579,Q9H4A4,Q9NY33,Q86TI2 5 +Thyroid hormone receptor binding 0.2807001174655285 0.0922680509701473 0.9264850716919472 1.0 1.0 9 Q9Y2X0 1 +Map kinase kinase activity 0.2806791813768825 0.0922353103578397 0.9265110839979778 1.0 1.0 9 P28482 1 +Camp dependent protein kinase activity 0.2600776351149524 0.0898120792194124 0.9284365491558112 1.0 1.0 4 Q12802,P54619,P17612 3 +Cyclic nucleotide dependent protein kinase activity 0.2600776351149524 0.0898120792194124 0.9284365491558112 1.0 1.0 4 Q12802,P54619,P17612 3 +Beta catenin binding 0.2984022976677523 0.0892048381276424 0.9289191204394662 1.0 1.0 15 Q8WZA0,P49841,Q9Y5K6,Q9HCK8 4 +Receptor tyrosine kinase binding 0.3039969027587184 0.088806018660275 0.9292360743939708 1.0 1.0 17 Q06124,P51452,Q13501,Q14152 4 +Estrogen receptor binding 0.2922964446580386 0.0846936458604554 0.9325049476868656 1.0 1.0 14 A5YKK6,P09874 2 +4 iron 4 sulfur cluster binding 0.3156227877941883 0.0832153043975337 0.933680343797506 1.0 1.0 23 P21399,Q07864,Q9H9T3,Q9Y5Y2,P28340,O00217,P18074 7 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.2474626865671682 0.0774591418297812 0.9382582936745224 1.0 1.0 3 Q14534,Q16850 2 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.2651082740098214 0.0750333619632449 0.940188167692776 1.0 1.0 8 P30044,P98170,Q15418,Q9UKL3 4 +Nuclear receptor coactivator activity 0.3099605133307449 0.0724300777202845 0.942259649088696 1.0 1.0 24 Q16512,P17096,Q15648,Q9UPT9,Q92600,Q99816 6 +Epidermal growth factor receptor binding 0.2480658263053995 0.0678580966334206 0.9458985958678428 1.0 1.0 5 Q92600 1 +Endopeptidase activity 0.3124544059051189 0.063826692068431 0.9491082243897992 1.0 1.0 66 P49721,Q70CQ2,P55212,P42574,Q9Y4P1,Q93008,Q14674,P49720,Q6NTF9,P52888,Q9UDY8 11 +Actin binding 0.1678116287180897 0.0613700115176544 0.9510645346703476 1.0 1.0 118 Q9UM54,O43795,P31146,O15357,P57737,Q7L576,Q9UPN3,P35241,Q13045,Q86TU7,Q96RD7,Q9H269,O94832,P55196,Q9P1Y5,Q92614,P47755,Q9Y613,Q9BPX3,P78559,P35580,P35579,P46940,Q9UHB6,P46821,O00401,Q66K74 27 +Exoribonuclease activity 0.306549805632263 0.0608824185134435 0.9514528514622698 1.0 1.0 27 Q8IZH2,A5YKK6,Q9Y2L1,Q9H9L3,Q96C86 5 +Cadherin binding 0.168388286674677 0.0583598338006081 0.9534620081976048 1.0 1.0 212 O43795,P28072,O00299,P46109,Q8TCG1,P62424,P42356,P49327,Q13190,Q9Y5K6,P15880,Q9UPN3,P13639,P35241,P83731,P26196,Q02878,Q9BY44,P31949,P47914,P62750,Q9H2G2,Q9H4M9,Q06124,Q9UBC2,P62854,P55196,Q9NUQ8,P61313,Q7Z478,Q7KZI7,Q16513,Q92616,Q9UQB8,P50914,Q9BPX3,P26641,Q14258,Q14008,O95067,P22681,P31939,P35579,P40818,Q92522,Q6PKG0,Q9H223,P46940,Q9HC38,Q9UHB6,Q9Y5X3,P49207 52 +Guanyl nucleotide binding 0.1675449976528787 0.0580899446084245 0.9536769839088752 1.0 1.0 120 Q2NL82,P84085,Q9Y3Z3,Q96DE0,O00178,Q9Y3I0,P13639,Q9BUF5,Q14692,P15531,Q13885,P49770,Q9Y6B6,P04350,Q9H4M9,O60942,Q9NZB8,P36915,P50570,O00429,Q9Y295,Q05639,P22392,P49903,P60953,Q9H223,O60841,Q9Y450,Q8TCY9,P11908 30 +Transcription coregulator binding 0.3002070632239101 0.0563374660905143 0.9550729725919836 1.0 1.0 26 Q92908,P17096,Q15648,P51858,Q14839,P51532,Q15369,Q9UQB8 8 +Protein self association 0.2687830181339665 0.0562447855293929 0.955146803913733 1.0 1.0 14 Q9Y613 1 +Monocarboxylic acid binding 0.278854693318817 0.0545567878037135 0.9564915657907128 1.0 1.0 18 P29375,Q00169,P06737 3 +Exoribonuclease activity producing 5 phosphomonoesters 0.2934197205382581 0.053946169503184 0.9569780522516116 1.0 1.0 24 Q9Y2L1,Q9H9L3,Q8IZH2,A5YKK6 4 +Carboxylic acid binding 0.3168465171447006 0.0534041145310326 0.957409926971377 1.0 1.0 39 P00374,O75592,Q00169,P06737,P27708,P29375 6 +Metalloaminopeptidase activity 0.2572997591405214 0.0514779086602485 0.9589447048427052 1.0 1.0 12 Q9UIQ6,P50579,Q9H4A4,Q9NQW7,Q9NY33 5 +Ribosome binding 0.3162608903667814 0.051156575150898 0.9592007545173198 1.0 1.0 41 P62495,P38935,Q9BXJ9,Q8TEQ6,P09132,P13639,O76094,P46379,Q9BY44,Q86UK7,Q99543,Q9UHB9,P42345,O60678,Q92616,P63244,Q06787,P63241,P60059 19 +Cis trans isomerase activity 0.296365751604589 0.0488892978140379 0.9610075177716556 1.0 1.0 28 Q9Y237,O00170,Q15257,Q96BP3,P62942 5 +Rrna binding 0.3147008893411334 0.0471654038320639 0.9623814005631576 1.0 1.0 46 P46782,Q9NY93,P62701,Q9NV31,Q9NR30,P62269,Q9Y2R5,Q9NUL7,P61927,P32969,P46777,P62280,P62917,P62750,Q15050,P46781,Q9NQ55,P62263,P62829,Q92979,P62277,P39023,Q9H9Y2 23 +Smad binding 0.2505080827970256 0.0458090863827619 0.9634624165291152 1.0 1.0 12 Q93008,P62942,P09874 3 +P53 binding 0.2812579471367325 0.0453458257493106 0.9638316613167064 1.0 1.0 23 P49841,P42858,P61289,P51532,Q00535,O14744,Q9UER7,Q9HCK8 8 +Translation elongation factor activity 0.252858068903615 0.0451162815481487 0.964014623837904 1.0 1.0 13 Q05639,O00178,P13639,P63241,P26641 5 +Heparin binding 0.2457582346043825 0.0422877125971307 0.9662693404521348 1.0 1.0 12 O43670,P51858,P47914,P20248 4 +Vitamin binding 0.3074632403610893 0.0404487314786295 0.9677353799124446 1.0 1.0 52 P00374,O75592,O00764,O94903,P06737,Q99707,P49327,P29375 8 +Transcription coactivator activity 0.2282313612921795 0.0391634082388278 0.9687601072368488 1.0 1.0 89 Q15648,Q9UPT9,O00170,P51532,Q6P1K2,Q9UER7,Q9Y5V3,Q86TU7,P29375,P17096,P49407,Q14258,Q16512,P22392,P09429,P27695,Q9Y6J9,Q9Y2X0,Q99816 19 +Mannosyltransferase activity 0.2202630005977243 0.0370801171558378 0.9704211253359734 1.0 1.0 7 Q9H553,Q2TAA5,Q9BT22,Q6ZXV5,Q9BV10,O75340 6 +Transcription coactivator binding 0.2180089112127106 0.03580163759525 0.971440527293469 1.0 1.0 7 Q15648 1 +Protease binding 0.2711955695821458 0.0327775659220449 0.9738519683989272 1.0 1.0 27 P14174,P42574,Q6NTF9,Q96RD7,Q15020,Q9UDY8 6 +Endopeptidase activator activity 0.2007993898175392 0.0310969085093705 0.9751922551309062 1.0 1.0 5 P61289 1 +Molecular carrier activity 0.2797933392998042 0.0303920500032814 0.9757543851069526 1.0 1.0 34 O75880,O14980,Q9HAV4,Q96P70,Q53FT3,P55060,Q92973,Q9Y5L0,O00629,Q9UIA9,Q9UI26,Q8TEX9,O00410 13 +Actin filament binding 0.2675903952849487 0.0280818562050717 0.9775968650177675 1.0 1.0 73 Q9UM54,O43795,P31146,P57737,Q9UPN3,Q13045,Q96RD7,Q9H269,O94832,P55196,Q9P1Y5,Q92614,P47755,Q9Y613,Q9BPX3,P35580,P35579,P46940,Q9UHB6,Q66K74 20 +Phosphatidylinositol binding 0.2878579085223833 0.0269880837540817 0.978469238357642 1.0 1.0 53 Q00169,Q7Z3T8,O00443,Q8TEW0,P46940,A1X283,Q92538,Q9BPX3 8 +Poly purine tract binding 0.2253111363763475 0.0269740158322714 0.978480458850383 1.0 1.0 15 Q06787,Q86TB9,Q92499 3 +Protein tyrosine kinase binding 0.2424896959841823 0.0266891962502 0.9787076302077298 1.0 1.0 21 Q06124,P51452,Q13501,Q14152 4 +Adp binding 0.2344250048131793 0.024132946749766 0.9807465632639198 1.0 1.0 21 Q9UM54,P52701,P35579,Q92614,Q03518,P11908 6 +Histone methyltransferase activity 0.229770905008535 0.0236615090216003 0.9811226087542312 1.0 1.0 20 Q86TU7,O14744,Q99873,Q9BV86,Q6UXN9 5 +Organic acid binding 0.2634905771646296 0.0225819607636823 0.9819837333843828 1.0 1.0 36 P00374 1 +Transmembrane transporter binding 0.2557067278821502 0.021924704726479 0.9825080179877508 1.0 1.0 33 Q96RD7,P42858 2 +Dna binding transcription factor activity 0.2657314040210406 0.0210314408011827 0.9832205750858204 1.0 1.0 41 Q92908,O75569,P51858,Q8WVM0,Q00653,Q99459,P10589,Q96KM6,Q9H582,P40763,P85037,Q15365,Q8IWI9,Q9Y2X9,Q99640 15 +Molecular adaptor activity 0.1544255123966537 0.0210258219150532 0.9832250573171736 1.0 1.0 123 Q13616,A5YKK6,Q7KZN9,Q13190,Q15369,Q96D46,Q5VYK3,Q01804,P40763,Q9UH99,P18074,Q9Y3I1,Q06124,Q969U7,O60271,Q9UQB8,P78559,Q04637,P35579,Q99996,P46940 21 +Protein kinase a binding 0.2160663282584413 0.0207115776634325 0.9834757333618498 1.0 1.0 20 P49841,Q9Y6D5,P17612,Q99996 4 +Dioxygenase activity 0.2252394686305161 0.0206710230101317 0.9835080843676272 1.0 1.0 23 P29375,Q7LBC6,Q6P6C2 3 +Hsp70 protein binding 0.2061957137226552 0.0202266675648875 0.9838625545944352 1.0 1.0 18 Q9NZJ4,P06493,P53602,Q53FT3,P46379,O60884,P31689,Q99543 8 +Growth factor receptor binding 0.190451644877122 0.0201294651902145 0.9839400950813488 1.0 1.0 14 Q9Y5K6,Q92600,Q92990 3 +Protein phosphatase regulator activity 0.2107181811124757 0.0194029553392192 0.9845196528334306 1.0 1.0 21 Q9UPN7,Q15257,Q9Y570,P78318,Q8TF05,Q5H9R7,Q9UQ13,Q14738,P63151,Q96QC0 10 +Phosphatase regulator activity 0.219497592500711 0.0184071474533618 0.9853140505663204 1.0 1.0 26 Q9UPN7,Q15257,Q9Y570,P78318,Q8TF05,O95248,Q14738,P63151,Q96QC0 9 +Protein tyrosine kinase activity 0.1742510206134677 0.0183618550766975 0.9853501825477418 1.0 1.0 15 P36507,P49761 2 +Hsp90 protein binding 0.1762671201152139 0.0173847281810075 0.986129692461812 1.0 1.0 19 Q9UHD1,P68400,Q15185,Q00535,O95433,O94966 6 +Protein methyltransferase activity 0.2026631440866901 0.0166223801193153 0.9867378702706704 1.0 1.0 27 Q15047,Q86TU7,O60678,O14744,Q8NCA5,Q99873,Q9BV86,Q6UXN9 8 +Carbon carbon lyase activity 0.1414334536993085 0.0162661742488784 0.9870220430088804 1.0 1.0 22 P04075,Q9NZB8,Q6P996,P53602,P30046,P09972,P11172,Q9H993,Q16822 9 +Calmodulin binding 0.2365349524907823 0.0161427135362202 0.9871205374729292 1.0 1.0 39 Q5T4S7,O94832,Q13555,P35579,Q9P1Y5,P49327,P46940,Q01844 8 +Promoter specific chromatin binding 0.1894952585090536 0.0160390044598195 0.9872032746320976 1.0 1.0 27 P26358 1 +Phosphoprotein binding 0.1951353199287223 0.0158030781184563 0.987391492760686 1.0 1.0 29 Q06124,P28482,P22681,P42345,P29372,P46109,Q13526,O15344,Q8IWS0,P43034 10 +Protein phosphatase binding 0.209699430122528 0.013377984380731 0.9893262311904656 1.0 1.0 44 Q8IV63,Q9Y570,Q9UQ13,P62136,O95793,Q5H9R7,Q9Y496,P40763,Q96QC0,Q9UPN7,O00203,Q9UJX5,Q15257,Q9UHD2,O60493,P63244,P78318,Q16539,Q96GX5,P46940,Q15334 21 +Magnesium ion binding 0.2303121975711265 0.0131543578025532 0.9895046436839934 1.0 1.0 77 P00492,Q9UBT2,Q9UKK9,Q96DE0,P78362,P52701,O95394,P17612,P15531,Q14558,Q8NB49,P33316,O00764,Q9H2U2,Q15418,Q7KZI7,O60256,Q96SB4,Q15382,P51003,Q7Z460,Q9NSD9,P53350,P11908 24 +Transcription corepressor activity 0.2366477094323353 0.0127777001180692 0.9898051477722538 1.0 1.0 57 O75182,Q15648,Q9UIV1,P09429,P27695,O75925,Q99816,P51532,Q6W2J9,Q9UER7,Q9BQ70,Q9UKL3 12 +Single stranded dna binding 0.2350508532662387 0.0124041500160057 0.9901031740054508 1.0 1.0 59 O95347,Q9NUW8,P67809,P35244,P20585,P54132,P46063,P38935,Q9BUI4,Q96FZ2,Q9Y3Z3,P33992,Q15554,Q9GZR2,P33991,P09884,Q9NTJ3,P33993,P09429,Q9H2U1,Q15365 21 +Glycosyltransferase activity 0.1606281929802237 0.0114965452036231 0.9908272861403438 1.0 1.0 53 P00492,P07741,O43505,Q9H974,P06737,P09874,P43490,Q9Y673,Q8IXJ6,P11172,P46976,Q13126,Q9BV10,P35573,P11216,P13807 16 +Phosphatase binding 0.1719459480226733 0.0113606563950392 0.9909357026420864 1.0 1.0 54 Q8IV63,Q9Y570,Q9UQ13,P62136,Q5H9R7,Q9Y496,P40763,Q92796,Q96QC0,Q9UPN7,O00203,Q9UJX5,Q15257,Q9UHD2,O60493,P63244,P78318,Q16539,P28482,Q96GX5,P46940,Q9Y2V2,Q15334 23 +Heat shock protein binding 0.1914356032457908 0.0113018913007738 0.9909825873934628 1.0 1.0 55 Q9UHD1,P68400,Q00535,Q15785,Q9UER7,P46379,P42858,O95433,Q99543,Q0VDF9,Q9NZJ4,P53602,Q53FT3,O60884,Q15185,P31689,O94966,Q9UNN5,Q6W2J9 19 +Cis regulatory region sequence specific dna binding 0.2189547877222128 0.0111893841749402 0.9910723494160704 1.0 1.0 60 Q92908,O75569,P17096,Q12830,P51858,P42345,Q00653,Q13330,P10589,Q9H582,P40763,P85037,O14744,Q8IWI9,Q9P2D1,Q9Y2X9,Q99640,Q9BQG0 18 +Enzyme inhibitor activity 0.1829291482171758 0.008170892472516 0.9934806435907708 1.0 1.0 76 Q9UHD1,Q9Y570,P42771,Q92990,P98170,P62081,P62841,P61927,P23381,P46777,Q86XI2,Q14558,Q96QC0,P30044,P42574,P60866,Q15418,P49407,O43924,O60256,P61221,P62829,P63244,Q9NR09,P47897,Q13464,P46940,O00410 28 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c1492778ceb9ce8317a4c6caaa5c127be090a7ba --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Angiotensin receptor binding", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "Butyrate coa ligase activity", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calcium release channel activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonate dehydratase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol 1 4 5 trisphosphate binding", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intracellular ligand gated ion channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated calcium channel activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Microtubule severing atpase activity", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin heavy chain binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur amino acid transmembrane transporter activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo polymer binding", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRK1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C2CD5", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COG2", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAHD2A", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLYWCH2", "FMR1", "FN3KRP", "FNDC3A", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFKB2", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TLN1", "TMED10", "TMED9", "TMEM165", "TMEM201", "TMEM38B", "TMEM43", "TMEM70", "TMF1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS16", "VPS18", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WASF2", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZNF644", "ZNF703", "ZPR1", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AARSD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACACA", "ACLY", "ACO1", "ACOT7", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ADPRHL2", "AFDN", "AGL", "AHSA1", "AIP", "AK6", "AKAP13", "AKAP9", "AKT2", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMPD2", "ANAPC4", "ANKFY1", "ANKHD1", "AP1B1", "AP1M1", "AP2A1", "AP2A2", "AP3B1", "APEX1", "APRT", "ARF5", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARMT1", "ARRB1", "ASCC3", "ASNS", "ATAD2", "ATAD2B", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP6V1D", "ATP6V1G1", "ATR", "AURKA", "B4GAT1", "BAG6", "BAIAP2", "BAZ1B", "BAZ2A", "BCOR", "BICD2", "BIRC6", "BLM", "BMS1", "BPTF", "BRD2", "BRK1", "BTAF1", "BTF3", "BUD23", "CAD", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAPN2", "CAPZA2", "CARHSP1", "CARS", "CASP3", "CASP6", "CASP8AP2", "CBL", "CCDC51", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CDC25C", "CDC34", "CDC42", "CDC5L", "CDC6", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDKN2A", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHM", "CHORDC1", "CHST14", "CHTOP", "CHUK", "CIP2A", "CKAP5", "CKB", "CLASP1", "CLIC1", "CLIC4", "CLK3", "CLTC", "CLUH", "CMTR1", "CNOT1", "CNOT7", "CNOT9", "COPA", "COPB1", "COPG1", "COPG2", "COPS5", "COPS6", "CORO1A", "CORO7", "COX15", "CRKL", "CSE1L", "CSK", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CTPS1", "CTU2", "CUL1", "CWF19L1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAXX", "DCAKD", "DCPS", "DCTN1", "DDT", "DDX1", "DDX21", "DDX24", "DDX27", "DDX28", "DDX46", "DDX56", "DDX6", "DHFR", "DHX16", "DHX29", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DIAPH1", "DIP2B", "DIS3", "DLG3", "DLGAP5", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJC2", "DNAJC21", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DOCK7", "DPH5", "DPP3", "DPP9", "DPYSL5", "DRG1", "DUS1L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "ECT2", "EDC3", "EEF1A2", "EEF1G", "EEF2", "EHD1", "EHD4", "EIF1", "EIF2A", "EIF2AK2", "EIF2B2", "EIF2B5", "EIF2D", "EIF3A", "EIF3D", "EIF4A2", "EIF4E2", "EIF4G1", "EIF4G3", "EIF5A", "EIF5B", "ELAC2", "ELOC", "ELP1", "ELP3", "EMG1", "EP400", "EPB41L5", "EPRS", "EPS15L1", "ERCC2", "ERCC6L", "ESD", "ESPL1", "ETF1", "EWSR1", "EXOC2", "EYA3", "FAF1", "FAM120A", "FAM98A", "FANCI", "FARSB", "FASN", "FAU", "FBXO7", "FHOD1", "FKBP1A", "FLAD1", "FLII", "FLYWCH2", "FMR1", "FN3KRP", "FOXK1", "FRA10AC1", "FTSJ1", "FTSJ3", "G6PD", "GAK", "GALK1", "GALM", "GAMT", "GAPVD1", "GATA6", "GBF1", "GCN1", "GDE1", "GEMIN4", "GEMIN5", "GLMN", "GLOD4", "GLRX", "GMPPA", "GNE", "GNL1", "GNPDA1", "GPATCH4", "GPATCH8", "GPI", "GPKOW", "GSK3B", "GTF2H4", "GTPBP1", "GYG1", "GYS1", "H1FX", "H2AFY", "HAUS6", "HAUS8", "HBS1L", "HDAC1", "HDGF", "HDGFL2", "HDHD2", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC5", "HIKESHI", "HK2", "HLCS", "HLTF", "HMCES", "HMGA1", "HMGB1", "HMGCR", "HPRT1", "HSPA14", "HSPA1B", "HTT", "HUWE1", "IARS", "IDE", "IGBP1", "IGHMBP2", "ILK", "IMP3", "INPPL1", "IPO11", "IPO4", "IPO5", "IPO7", 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pval_std pval_50 pval_100 pval_250 pval_500 +Abnormality of finger 74 298 4.03101788226672 5.553581768591442e-05 51.25728155339806 273.74029126213594 -0.048521333853787 0.8795792656966821 17.36799926402839 30.461148706141906 0.4300311611533953 0.2297287888537679 0.0485468580972174 0.0011302892626938 0.0049812228274191 1.5226570914854508e-05 +Abnormality of the forehead 90 323 3.964952990706764 7.341041293074113e-05 59.98300970873787 298.5145631067961 -0.1139301355929378 0.847489711817479 20.43857011200164 32.27517127948052 0.4655961361938476 0.2519818946435337 0.2260264699499306 0.0072632646207988 0.0053446018242789 1.7782989426907477e-05 +Abnormality of the pinna 70 248 3.734784339197598 0.0001878761158493 44.38106796116505 227.75485436893203 -0.10546418906282 0.8527592666347761 17.318488095888167 23.05713883361038 0.4441472818934013 0.2431683957368847 0.1721745577357914 0.0338473516873445 0.0081073843363257 4.7353988817145245e-09 +Abnormal finger phalanx morphology 50 177 3.6508804032297104 0.0002613429215694 35.15533980582524 164.00485436893203 -0.1772712388298519 0.7643044491513388 12.478530908019424 20.016618719923493 0.5370742906588031 0.2735158693813097 0.0403001312128018 0.001617496185364 0.009956108787105 0.0001800892675492 +Neoplasm by histology 30 104 3.4755012587648024 0.0005098995996688 24.1626213592233 100.4004854368932 -0.0695215913268657 0.6299759235194263 11.89763217539116 10.591363937454569 0.8403649349967283 0.3117129870709569 0.1441765718609627 0.0162555442540069 0.002842562722737 1.0104001055983451e-05 +Neoplasm 63 234 3.4372038936796376 0.0005877529763804 40.69417475728155 217.83009708737865 -0.0252514260799582 0.8635181551533664 16.841743822971125 21.05103062279461 0.4121049236161889 0.2297762827647043 0.3523863026901213 0.0762662928440676 0.0094674233369183 5.544381554289029e-07 +Abnormal eyelid morphology 88 371 3.399762083353806 0.0006744450994624 75.14320388349515 342.7742718446602 -0.401959315495849 0.6807287105327863 26.125562704530108 37.13711171075859 0.5812016900899709 0.3135172172139908 0.0829357060819319 0.0039431784143062 0.005114682249459 7.11769696942838e-07 +Abnormality of the outer ear 88 360 3.393441670244486 0.000690202559108 63.699029126213595 333.93203883495147 -0.0871527406817132 0.864100250531633 21.557029782369987 34.312389037696285 0.4356426493757938 0.2418591979861644 0.1531812499466158 0.0307666738303875 0.0098851628848546 4.40352381429151e-07 +Abnormal location of ears 71 258 3.223070499414618 0.0012682433539412 44.41504854368932 237.9538834951456 0.0573706016617153 0.8767599664892582 15.161911487312535 25.154480182821903 0.4422303529904745 0.2317200782883387 0.1935776535162458 0.019774225545287 0.0037335504764359 3.0380521646563725e-06 +Abnormal scalp morphology 40 127 3.152978039334933 0.0016161396453144 32.713592233009706 115.33009708737865 -0.6076773774108495 0.5494039121685904 12.796787738188454 12.408021481201292 0.7886544230904604 0.3284735384169909 0.0542489687014012 0.0001289840735502 0.0025264803387909 1.351155785023328e-07 +Abnormality of the palpebral fissures 54 238 3.113315175580688 0.0018499834088911 45.83009708737864 218.7014563106796 -0.1389915494936317 0.8200378415875396 15.852024065742055 26.255386831752915 0.4574843529060138 0.2555053198813087 0.0836077723483382 0.0078483182421399 0.0219172823266082 0.0005365093649856 +Abnormality of globe location 77 293 3.0781746722825054 0.0020827279808481 53.16019417475728 272.24029126213594 -0.1086730780614653 0.871088380189231 18.175214317753635 30.4132225318123 0.3692552248667367 0.2201968618542093 0.5141105520948058 0.1213691788684428 0.0352572722076823 0.0003246721210542 +Abnormality of the cervical spine 31 107 3.0163451726246366 0.0025584183718185 24.604368932038835 106.0 -0.2058800903907574 0.6703029508269278 9.619775361192769 11.283633650093154 0.7418506634396657 0.3072107111122492 0.1850444966260396 0.0007474957081536 0.0387645052962459 0.0023449519096762 +Hypertelorism 59 219 2.9988041448607023 0.0027104147944387 41.00485436893204 199.54368932038835 -0.1289704443737652 0.8270064544292263 14.930908052427814 23.502231540000384 0.4308163262028535 0.2445868894863604 0.3113391603468238 0.0249187793307261 0.0795908799188513 0.0015909869060388 +Abnormal thorax morphology 55 240 2.971811728250504 0.0029604816543318 45.70873786407767 223.58495145631068 0.1329293284361508 0.8464208669117267 12.555609173113975 23.25116275926513 0.4910267466787029 0.2593045889961468 0.1877192160612583 0.0408149744658122 0.0208453113107779 9.427558951341924e-06 +Abnormality of facial skeleton 75 338 2.956884592280076 0.0031076440895776 59.74029126213592 318.34223300970876 -0.0426211149457642 0.8896091359272095 18.198421672537343 37.122165974847874 0.3671912619040463 0.2108724938829779 0.4500420104266284 0.0533796735476975 0.0134739476125014 0.0003983958437887 +Abnormal thumb morphology 31 117 2.954970718144416 0.0031269872808794 24.854368932038835 110.56067961165049 -0.1925224576061537 0.7454467615377586 11.23397047187317 12.274320321058648 0.5530662451663703 0.2735165942045226 0.2046889324448847 0.0925837406496855 0.2677315369575444 0.002409106936536 +Aplasia hypoplasia affecting bones of the axial skeleton 60 247 2.903663051205182 0.0036882486425775 46.351941747572816 235.20873786407768 0.0705176603751312 0.8826262900407661 14.130629168428268 28.430380327942835 0.4118709944879549 0.2246671950863801 0.409146041508718 0.0586469001760903 0.0231335939282592 0.0003478436231408 +Wide nasal bridge 46 167 2.780192659458044 0.0054326657093592 36.23543689320388 156.3495145631068 -0.2018741606583665 0.7662798409866993 12.545080130821642 15.177723032898584 0.5011576393054168 0.2720230799034255 0.154423116545592 0.0234532948585938 0.0095700049905547 0.0003148938259696 +Thin vermilion border 41 140 2.7570740830089067 0.0058321136513854 32.067961165048544 128.29368932038835 -0.3825638986682543 0.6754620785075162 12.735366348767782 13.391370173614764 0.5861904760789012 0.293712556058585 0.462855896769634 0.0905286595830776 0.0124517316499526 0.0001024907429822 +Abnormality of the breast 28 111 2.7522435997104213 0.0059188474975253 22.368932038834952 102.93203883495146 0.0128788773705202 0.7786041561313972 8.40508432728544 12.34339738280949 0.5782262129283021 0.2768339788992208 0.7827017212489784 0.0304244095122772 0.0202445244065494 0.0006227838526228 +Ankyloblepharon 3 5 2.7338481378144173 0.0062598908466551 2.0388349514563107 4.847087378640777 0.153347487618514 0.5812737688035945 1.4085200530163813 1.5791162153214648 0.8403756351562842 0.3008172003950811 1.0 1.0 0.2917500038862815 0.0037759888499611 +Abnormal hair morphology 87 355 2.703725134891508 0.0068566981429527 67.74029126213593 332.82766990291265 -0.2470394453928047 0.7696247327717582 21.749858339291407 33.48607755047281 0.5038423815335713 0.2849850293419126 0.1477535862728152 0.0285191984532571 0.0027297026303465 1.4374545392712486e-07 +Abnormal external genitalia 70 298 2.681703993518875 0.0073248240629317 54.08980582524272 284.6990291262136 0.0036117519724346 0.8934779758008135 17.546310235343427 29.77580791383303 0.4033495622370615 0.2227615969762441 0.3844377103666905 0.0609084738390139 0.037167697602925 7.587183343661396e-05 +Slanting of the palpebral fissure 45 207 2.666239475933435 0.0076705032020414 39.49029126213592 189.0752427184466 -0.1515468355725298 0.814525148906387 15.448549211194573 22.990324446274595 0.4594299648953945 0.2582572970447012 0.1199866131938089 0.0059481600478092 0.0251360321627063 0.0021252597008588 +Abnormal jaw morphology 67 299 2.657689358859859 0.007867837682705 55.12378640776699 282.2888349514563 -0.1107038411786406 0.8674294912263407 17.47346718788314 33.526349173954564 0.3949211078277473 0.2290191772790158 0.3461871880071503 0.0217271761108239 0.0127407721871235 0.0003429225204997 +Abnormality of digestive system morphology 61 249 2.641545543541478 0.0082528710533837 43.70388349514563 239.3009708737864 -0.0284471210482883 0.903078496841084 15.057162423852352 24.600234804884735 0.3190914089309858 0.1874103435176322 0.6768016010892083 0.0804594859608247 0.2110510061673901 0.0004310056801464 +Abnormal intestine morphology 52 197 2.617868181771261 0.0088480977858083 35.30582524271845 189.34466019417476 0.0489931305590195 0.8630542314814685 11.207385959586196 20.03147149181134 0.4226395241552775 0.2289681331371937 0.7635590862158177 0.0927794186292096 0.1459271396840737 0.0013135630533719 +Panhypogammaglobulinemia 3 5 2.6106919649700115 0.0090359242795132 2.162621359223301 4.973300970873787 -0.0382869438252732 0.5768979381654653 1.3900691197210433 0.5675409199558215 0.8364197693271596 0.2984738250747459 1.0 1.0 0.2740704871267072 0.0028040242445346 +Abnormal hand morphology 37 121 2.5996642049342324 0.0093315022186608 24.18446601941747 110.09223300970874 -0.2581834342957215 0.7026306719846498 10.331399563847796 12.397002372719044 0.6422641154120181 0.3009736359720412 0.4267494331732555 0.0083073369666447 0.0153091906958449 0.0001511689207145 +Abnormality of the neck 48 180 2.5915620687274137 0.0095541305257993 34.13106796116505 167.26941747572815 -0.0509285658251984 0.804373887487248 11.940276371606007 17.057946263505073 0.5316163009634547 0.2670897320998164 0.3973626214286082 0.0018271432287117 0.0111418580436448 5.1172426577335024e-05 +Gastritis 3 5 2.5528152386351968 0.0106856163131077 2.4635922330097086 5.218446601941747 0.1572647267694168 0.5819623396052007 1.6564480388985168 0.7763803958069186 0.8288201428853897 0.2999830210321953 1.0 1.0 0.2917500038862815 0.0037759888499611 +Abnormality of upper lip vermillion 47 132 2.518941115131916 0.0117708340026942 28.33495145631068 123.33495145631068 -0.2701758669126816 0.7471083445508511 11.68225946307871 12.479087039810167 0.5094187346905122 0.2794228578551926 0.7827017212489784 0.3524455981840583 0.1395112634870597 0.0013182562343927 +Abnormal morphology of the great vessels 48 183 2.50165844720694 0.0123613115163889 38.866504854368934 173.22815533980582 -0.2518377371082049 0.7350981206087794 15.357997961198915 19.641109639207368 0.5462983988847548 0.2868111108414395 0.2348454469842963 0.0595702960590621 0.1254030968109254 0.0023478156048081 +Thin upper lip vermilion 30 103 2.4967812745189963 0.0125326232420648 24.524271844660195 95.17961165048544 -0.3589986494224335 0.6889537337768582 10.573455185835762 9.204092158955378 0.5633080499021588 0.2821582272636956 0.6739366433451586 0.1801717843759775 0.0544220031082801 0.0008353523684643 +Abnormal hair pattern 34 127 2.4806864484308044 0.0131129664850595 33.172330097087375 114.7378640776699 -0.5540879789377412 0.5546797608948976 12.47120611445775 12.946087736101804 0.7535563833067269 0.3160829779523001 0.04493007812576 0.0054481937966139 0.0193376420372261 1.5632895973977172e-05 +B cell lymphoma 2 6 2.4648077109942577 0.0137086798033045 1.519417475728155 4.575242718446602 0.0811904420601796 0.4987660389463306 1.309825323893257 1.2720554001645352 1.0111528430722745 0.3041494499657511 1.0 1.0 0.0565188023636715 0.0401461367370898 +Abnormality of the lower urinary tract 53 229 2.4174929836256687 0.0156278352819674 42.28883495145631 216.26941747572815 0.0348283370820271 0.8777882338418204 13.464681293368304 22.40779893382489 0.381146700388608 0.216733112584296 0.0705358627680265 6.230755006041734e-05 0.0071965931315495 0.0001866987626107 +Aplasia hypoplasia of the extremities 47 192 2.389850898791425 0.0168552139918336 36.24029126213592 180.60679611650485 0.0646543125771677 0.8130083608706763 12.307469825573383 20.178469551094576 0.572550273121386 0.2795248681750475 0.2516830231916859 0.0016728817405208 0.0052711549434567 0.0023129959336369 +Abnormal aortic morphology 33 114 2.38816119718772 0.0169329129217399 25.796116504854368 107.0121359223301 -0.2520333299071822 0.7020741445246176 10.503452251060606 11.816039300807365 0.6088578049473303 0.2880258419743147 0.0570122322985015 0.0713912501616215 0.1208939821101373 0.0017712298352836 +Abnormal corpus callosum morphology 96 310 2.37374375066333 0.0176087662340187 51.95388349514563 283.78155339805824 -0.0442403919486197 0.8930822911985062 17.587791150108213 29.48804018736764 0.3335405439074819 0.19539302333426 0.4758997963035062 0.1684866850513106 0.0346462021128842 8.960598762513573e-05 +Chronic sinusitis 3 5 2.3670789737175366 0.0179291065597122 1.3713592233009708 3.533980582524272 0.1869859886183393 0.5216596330592604 1.1365315559872224 1.1044089398493104 1.019567154341152 0.3114965312404499 1.0 1.0 1.0 1.0 +Cardiac diverticulum 2 5 2.346715926624758 0.018939688544481 2.4271844660194173 4.475728155339806 -0.24944804991818 0.538390550018878 1.179122116649623 0.6437852291301127 0.8839589683623704 0.2996297425479004 1.0 1.0 0.2740704871267072 0.0228394808772788 +Decreased head circumference 107 478 2.330824461806634 0.0197626176944647 82.10194174757281 444.8470873786408 0.011085652934435 0.8723180886541458 25.570373028412018 42.16085029196968 0.428250097328845 0.2303881614612329 0.2376619153345747 0.1306977143568162 0.013532241354459 1.959227144052492e-07 +Aplasia hypoplasia involving the skeleton 71 316 2.3304575434918484 0.0197819814719018 57.771844660194176 302.6116504854369 0.0615277042780412 0.8814929752991282 17.051930491602196 33.85383574077355 0.4311950198795096 0.2328560599083964 0.6086237667185849 0.0711071271929823 0.0308047063824217 0.0020631351950589 +Abnormal libido 2 5 2.328785175393812 0.0198704491483852 1.5898058252427183 3.4902912621359223 -0.1545238946072398 0.5529593988398022 1.0631483566819735 1.022752289297587 0.9662512241207548 0.3098981737730627 0.0742352733278267 0.1432798584585485 0.3258327648280404 0.0401461367370898 +Epicanthus 51 178 2.3204687877761287 0.020315531486913 32.80825242718446 162.91747572815535 -0.0712137864128992 0.807731615365448 13.661285027275971 16.828604446258584 0.4696666341538635 0.2533162410578675 0.3416825323766459 0.2321971246745294 0.2483180193457212 0.0001264288911766 +Aplasia hypoplasia involving bones of the upper limbs 39 152 2.309439732469483 0.0209191923696085 29.98058252427185 140.64320388349515 -0.0420550902065938 0.7974466022573465 11.100582143856697 15.086848172941323 0.540224811596397 0.2716777612619044 0.1199496411889615 0.0013630289868556 0.007623899304561 0.0016379519041882 +Abnormality of upper lip 68 276 2.3005500180200227 0.0214170789840171 58.44417475728155 250.9368932038835 -0.362958820134301 0.7122559619402953 19.816127835105092 27.834826583442947 0.4868899569408253 0.2862479506800697 0.6313641583793597 0.1917693693162451 0.1959901766026492 7.788229653118723e-05 +Carcinoma 2 5 2.244701612309864 0.024787294478948 2.8300970873786406 5.334951456310679 -0.2603143120750294 0.5667157881439555 1.4228601683001765 0.5114625398622515 0.7791295671775087 0.2864126153831527 1.0 0.0832836732680532 0.0189506401306209 0.0680064706612652 +Abnormal penis morphology 47 200 2.233295741606333 0.0255294481596866 40.05825242718446 191.1043689320388 -0.1190901659476385 0.844344250056149 14.737393983062564 19.15778328836829 0.4321021152704566 0.234921331392881 0.2612749254549487 0.0144843820647904 0.0406018883780546 0.0005397169813237 +Bone fracture 2 7 2.218152154340187 0.0265444597589152 1.266990291262136 6.429611650485437 0.6828654589975502 0.427567080883794 1.283418398774736 0.8198963021456025 0.8587916801395448 0.288364223886542 0.0652597674910206 0.1265462710440741 0.0442367692127036 0.0280386150660574 +Spastic paraparetic gait 1 5 2.16261987806381 0.0305704280884189 1.4150485436893203 4.305825242718447 0.3635509519310221 0.4903206500262768 1.0681018221582994 1.328794273726026 0.9508496148587507 0.3046628067770794 1.0 0.0832836732680532 0.0189506401306209 0.0680064706612652 +Recurrent sinusitis 4 5 2.161186928240844 0.0306809027525991 1.8203883495145632 5.065533980582524 0.1394784458399675 0.5166478982984708 1.4062177615412113 1.385807554800596 0.9567780157824576 0.2991860115674145 1.0 1.0 1.0 0.7536837041511687 +Facial telangiectasia 3 5 2.1549798037649777 0.0311634146757338 1.6601941747572817 3.4320388349514563 -0.2950652728468559 0.5371763269095826 1.1474192067777895 1.137508228262826 0.913586577740909 0.3077796077679225 1.0 0.0832836732680532 0.1988473022417859 0.0680064706612652 +Rhinitis 4 8 2.1478880561556872 0.0317226494374645 2.400485436893204 6.20873786407767 -0.2210925482053607 0.562587408013379 1.7728534832548593 1.2695543745446805 0.8405579945137759 0.2993145104507038 1.0 1.0 1.0 0.8176627996413015 +Thyroiditis 3 8 2.143846281734781 0.0320452055892745 2.245145631067961 7.298543689320389 0.4876875666521073 0.4856749538817674 1.807643084926035 1.5298638227150836 0.926220199424323 0.3183675469870803 1.0 1.0 1.0 0.0451666412494461 +Abnormality of the hairline 30 99 2.1161108437469505 0.0343353814483133 26.929611650485437 89.74029126213593 -0.5881385847222433 0.5445849893195202 10.492364160399092 9.566985500441184 0.7770566474046292 0.3222184305811695 0.0831918202589172 0.0044803883732712 0.0154813136709962 5.099045983290382e-06 +Degeneration of the striatum 2 5 2.1034986279626646 0.0354222050997445 1.8932038834951457 3.9466019417475726 -0.2208237751780239 0.6131195486980414 1.2476200361279972 0.7050876877203788 0.7706398530337517 0.2901342554773621 0.0424464003246627 0.0832836732680532 0.1988473022417859 0.3623306062719575 +Large for gestational age 3 7 2.0978058793786505 0.0359222969468882 2.7815533980582523 8.388349514563107 0.0632770466831692 0.5874491218187148 1.8684528448843485 1.5468917140275038 0.8216368851097278 0.2910060687719157 1.0 1.0 0.5568666172945154 0.0747991773170861 +Hypoamylasemia 1 5 2.0916352657594093 0.0364711553265466 2.8106796116504853 4.349514563106796 -0.3895790510126309 0.5188038666741802 1.2668600907694247 0.5298605397040704 0.7959723995436226 0.275503702677409 1.0 1.0 1.0 0.0214944247869924 +Short digit 41 158 2.085897287869349 0.0369879280257754 30.66990291262136 148.08009708737865 -0.0865937834673512 0.7881676166854906 11.456662410266222 17.227937685160633 0.5017140908491723 0.261215088654629 0.1663805231870552 0.0277032366262318 0.0453680801390903 0.0036840574155448 +Abnormal renal vascular morphology 2 6 2.083642730232381 0.0371926771455268 1.3203883495145632 3.8737864077669903 0.1354967715812174 0.5099409340684035 1.1402911588075026 1.4476603933839365 1.0692559781762163 0.3262278930348921 1.0 0.1596960736798767 0.3582816735878424 0.0544656750173612 +Generalized hyperreflexia 2 5 2.0829786332522766 0.0372531712070507 2.186893203883495 4.628640776699029 -0.2531310969573107 0.543489767157738 1.2604988449455845 0.8392409290412601 0.9033937290799282 0.3138765671153907 1.0 1.0 1.0 0.0974859568290139 +Bronchospasm 2 6 2.076430555314007 0.0378541477052165 1.825242718446602 4.507281553398058 -0.2399545000973387 0.5812421280984764 1.241883821669583 1.2097682472233349 0.8352821599600367 0.3016962736115886 1.0 1.0 1.0 0.0141665154869097 +Abnormal bronchus physiology 2 6 2.076430555314007 0.0378541477052165 1.769417475728155 4.628640776699029 -0.198873072303825 0.568976562817921 1.2686422106818476 1.2523589768436805 0.8601494240274067 0.2992526047887839 1.0 1.0 1.0 0.0228394808772788 +Cerebellar hypoplasia 28 129 2.07585896236264 0.0379069971537218 25.716019417475728 119.48058252427184 -0.0311053428819295 0.8065683331706129 9.442695624651742 13.91433959132115 0.5088005426958597 0.2632436958751442 0.4788451615876514 0.1010569970097573 0.0328860553645794 0.0209398312168077 +Displacement of the urethral meatus 34 124 2.0698988241303566 0.0384618200889304 25.555825242718445 119.22815533980582 -0.0816412356514496 0.7822310709605177 10.669769019098595 12.016428216515324 0.5325948953544091 0.2627843234036119 0.1754294392216573 0.0006101441294703 0.0153091906958449 6.381534938710136e-05 +Abnormality of endocrine pancreas physiology 2 5 2.0671242145251534 0.0387224509497223 1.3155339805825244 4.837378640776699 0.6215811577057344 0.4583344908186231 1.0938714787177315 0.8647694133030841 0.8740678980182925 0.2977061936829481 1.0 1.0 1.0 1.0 +Abnormal nasal bridge morphology 64 288 2.0624059536693635 0.0391691029622474 54.720873786407765 264.50970873786406 -0.171708873062659 0.8114070224902274 19.630747905114752 27.156279162901143 0.4549018011422924 0.2639867673888756 0.1620186328893964 0.0324186196282579 0.0547065790763628 0.0015084330889929 +Depressed nasal bridge 42 173 2.06233996214369 0.0391753809146331 37.04854368932039 157.62135922330097 -0.3023293744010616 0.6920034409456117 15.200203524938328 16.827431663950957 0.5593148692650542 0.2852263992832307 0.3416825323766459 0.0222458166370358 0.008717568934421 0.000526500667787 +Flat acetabular roof 2 5 2.056799362991226 0.0397055293958859 1.720873786407767 4.514563106796117 -0.1891740428144695 0.5559794291197939 1.1394306249696262 1.328288757280043 0.8776444675092667 0.301700727273103 1.0 1.0 1.0 0.5726791496550556 +Abnormality of small intestinal villus morphology 2 6 2.052497659899443 0.0401213222417695 2.2354368932038833 6.570388349514563 -0.489926168189109 0.4779957582930658 1.542412230480548 0.7053174212499186 0.8555346714069033 0.2920331357526643 1.0 1.0 0.3422564852890665 0.0470360579614364 +Abnormal nasal mucosa morphology 3 5 2.0405146642378797 0.0412990919862481 0.9951456310679612 3.029126213592233 0.5238599989093575 0.4513344844257824 0.947646921342256 1.2303311629304916 1.1326671108301385 0.3296055235905867 1.0 1.0 1.0 1.0 +Megaloblastic anemia 1 8 2.031349381435425 0.0422195653568133 2.0145631067961167 7.970873786407767 0.7711391111646035 0.4443874876374949 1.4991199856764053 0.7465949978845597 0.8631923197432491 0.3098803608602049 0.0697581245313758 0.1349531130589082 0.050241067872642 0.1641299211995837 +Increased circulating iga level 3 5 2.017130449413345 0.0436819017719003 2.063106796116505 4.203883495145631 -0.2022464594033772 0.5381192544095769 1.3332557632885609 1.191468240848614 0.9334794867933294 0.3101194547959525 1.0 1.0 0.2373820829012167 0.0141665154869097 +Bronchitis 5 8 2.010273093909498 0.0444022929531291 2.1893203883495147 5.834951456310679 -0.0313285644779143 0.5402861922011556 1.700394735517199 1.9237760571417504 0.9236576899589776 0.3109441853019362 1.0 1.0 0.534424974066877 0.7880691909528317 +Abnormal leukocyte count 32 118 2.008558809043338 0.0445839433732149 24.689320388349515 107.39563106796116 -0.5228397589452107 0.5747125517373336 10.538675075817736 10.685317043958433 0.6825769884343547 0.3130678811353309 0.3826049998715105 0.2719222116478451 0.2270329430429883 7.185812549014004e-05 +Joint hypermobility 25 101 1.998313706664296 0.0456826604251912 19.983009708737864 93.09466019417476 -0.0789278755778876 0.7781458279893603 8.262513467809354 11.203469930194172 0.5239486632186459 0.2656687489851849 0.14867933693531 0.1292790415147156 0.1406335459994732 0.0010725569663023 +Abnormality of the endometrium 3 8 1.997161052317559 0.0458076904845849 2.8398058252427183 8.412621359223301 0.0708773158823896 0.621799672957091 2.119847943155827 1.129754644009171 0.744283429381666 0.2818057259513311 1.0 0.1758008751515455 0.0840389641709933 0.0144964406909979 +Abnormal pancreas size 3 9 1.9949761348129835 0.0460454828021215 3.7742718446601944 7.342233009708738 -0.4271306640724033 0.5507584258988134 2.0024301265056352 0.9279180496528368 0.754223955002155 0.293059716706977 1.0 1.0 1.0 0.1818418904091173 +Exercise induced muscle cramps 2 5 1.982906830199835 0.0473778375955973 1.3155339805825244 5.674757281553398 0.579896045951168 0.4229644702211388 0.9282259184279634 0.5176906236976432 0.9588843996375666 0.2865668825551565 1.0 1.0 1.0 0.0680064706612652 +Adenocarcinoma of the colon 13 21 1.968120401385828 0.0490541859930746 9.50485436893204 20.58009708737864 -0.5385965908043259 0.4099332106587272 4.098007534825994 1.3513359051095024 1.3067136508964234 0.352270731481182 0.0078974776787256 6.10556997769691e-06 2.232773959812015e-07 1.4363439368986103e-10 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..28e7cf3fee36ea23cbbb849f0e9f510b4f95beb6 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 4613, + "title": "Average number of proteins per term", + "value": 24.61846954259701 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..593838d473b0a7621a7befb5736b8a9e2cc44f95 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d0755101df7242a54fee80258468e6afd08ca62b --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1519 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Abnormality of finger 0.3137107391094135 4.0310178822667195 5.5535817685914424e-05 0.2260080771322163 0.0542032328029841 298 Q2VPK5,Q3SYG4,P08708,Q9UPP1,P62847,O15357,Q9Y263,Q93008,A5YKK6,Q07020,O43933,P10589,P51532,P42356,Q01968,O75909,P38935,Q13535,O43776,A1X283,Q9H3P2,P53618,Q9P2D1,Q5F1R6,Q9Y4A5,Q9NVI1,P57081,Q14999,O43709,P62081,P26196,P42766,P42858,Q14839,P41252,O00170,Q9Y296,P27635,P61353,P78527,Q8IWS0,P18074,O95352,Q9Y4X0,Q96EK5,Q06124,P49917,Q7Z6Z7,Q9NZJ4,P42345,P62854,P60866,O00443,P61313,Q08AM6,Q9H4L7,O14802,Q69YN2,Q92917,Q9BV10,O15111,O60826,O14646,P62266,P28482,P22681,P50851,Q15042,P62899,P61254,Q6W2J9,P46821,Q15334,Q9BPU6 74 +Abnormality of the forehead 0.301506818944057 3.964952990706763 7.341041293074113e-05 0.287271463574055 0.0542032328029841 323 Q2VPK5,P62847,O15357,P51532,O75909,Q12873,Q13535,Q9H3P2,P42695,Q9NVI1,Q9NR45,P42766,P42858,P08243,P40763,P46777,Q00534,Q92908,Q9Y4X0,Q96EK5,Q07864,P62854,O00443,P61313,Q08AM6,O14802,P47897,Q05639,O60826,Q15003,Q06787,P60953,Q8NC96,P62899,Q9Y223,Q9BTW9,Q9BPU6,Q01433,P36507,P08708,Q15436,O43776,A1X283,Q9BSJ2,Q9Y4A5,Q15021,Q14204,P27635,P26640,P78527,Q7Z6Z7,Q15477,O14646,Q15042,Q9UPP1,Q93008,A5YKK6,O43933,P21359,Q01968,Q14999,P62081,Q9Y296,P18074,Q96N67,P28482,P29372,P46821,Q07020,O00170,P61353,Q4G0J3,P57081,O43709,P26196,Q6PGP7,Q96F07,Q06124,P49917,P42345,P60866,Q00610,Q5SRE5,Q92917,Q16512,Q13555,P22681,P31939,P61254,P63241 90 +Abnormality of the pinna 0.3179348312017363 3.734784339197598 0.0001878761158493 0.5796863018526994 0.0542032328029841 248 Q2VPK5,P08708,Q07020,P62847,O00170,Q8IY37,O60701,A5YKK6,P61353,O43933,P10589,P21359,Q01968,O43776,A1X283,Q13535,Q9H3P2,Q5F1R6,Q9P2D1,Q9NR45,P57081,Q9UET6,Q14999,O43709,P62081,P26196,P42766,P42858,P08243,Q14839,Q6PGP7,Q9Y296,P27635,P18074,Q8IWS0,Q06124,Q9Y4X0,Q96EK5,P49917,O43505,Q07864,Q7Z6Z7,P26639,P62854,P60866,P61313,Q96N67,Q00610,Q5SRE5,O14802,Q9BV10,O15111,P46821,Q16512,O14617,O60231,P28482,P62266,Q13555,P22681,Q15042,P62899,Q7LBC6,P61254,P63241,Q6W2J9,Q9UID3,Q9BTW9,Q9BPU6,Q01433 70 +Abnormal finger phalanx morphology 0.3501401567072839 3.6508804032297104 0.0002613429215694 0.700527432182414 0.0542032328029841 177 P08708,Q3SYG4,Q9UPP1,Q07020,P62847,O15357,Q9Y263,Q93008,A5YKK6,P61353,O43933,P51532,Q01968,P38935,Q13535,A1X283,Q9H3P2,Q9P2D1,Q9NVI1,P57081,Q9UET6,P62081,P26196,P42766,P42858,P41252,Q9Y296,P27635,P18074,Q8IWS0,Q9Y4X0,P49917,Q7Z6Z7,P42345,P62854,P60866,P61313,Q08AM6,Q9H4L7,O14802,Q69YN2,Q92917,O15111,O60826,P28482,Q15042,P62899,P61254,Q6W2J9,Q9BPU6 50 +Neoplasm by histology 0.3827548086181674 3.4755012587648024 0.0005098995996688 0.904894334937356 0.0542032328029841 104 P08708,Q07020,P62847,Q8IY37,P61353,P20585,P42771,P21359,P49327,P28340,Q13126,P52701,O14965,P62081,P42766,Q6PGP7,Q01844,P18074,Q9H269,Q06124,Q07864,P62854,P60866,P61313,Q13501,Q15477,O60333,O96017,P62899,P54277 30 +Neoplasm 0.3118818505153696 3.4372038936796376 0.0005877529763804 0.9336028789439788 0.0542032328029841 234 P08708,Q07020,P62847,O00170,Q8IY37,Q93008,P61353,P20585,P51532,P42771,P21359,Q01968,P49327,Q13535,P28340,Q9H3P2,Q13126,Q9P2D1,Q5F1R6,Q9UER7,Q9NVI1,P52701,O14965,P06737,P62081,O76094,P17812,P42766,Q9Y5L0,P40763,Q6PGP7,Q01844,Q9UBS4,P27635,P18074,Q9H269,Q06124,Q9BUK6,P49917,Q07864,P26639,P42345,P50570,P62854,P60866,P61313,Q9H4L7,Q13315,Q9UDY8,Q13501,Q15477,O60333,O96017,O60826,P28482,P22681,P50851,P40818,P29144,P61254,P62899,Q8NCE2,P54277 63 +Abnormal eyelid morphology 0.2861670423471975 3.399762083353806 0.0006744450994624 0.9554999465076606 0.0542032328029841 371 Q2VPK5,Q3SYG4,P62847,O60701,P10589,P51532,O75909,Q12873,Q13535,Q9H3P2,P42695,Q9NVI1,Q9NR45,Q9NRZ9,P42766,P42858,Q00534,Q9Y4X0,Q96EK5,P62854,O00443,P61313,Q08AM6,O14802,Q9HCK8,O60826,P62899,Q9BTW9,Q9BPU6,Q01433,O75569,P08708,O43776,A1X283,Q9Y4A5,Q14204,P46778,P27635,P26640,Q8IWS0,Q7Z6Z7,O60231,O14646,P62266,Q9UID3,Q9UPP1,Q93008,A5YKK6,O43933,P21359,Q01968,P53618,Q9P2D1,P62081,Q14839,Q9Y296,P18074,Q96N67,O15111,P28482,P29372,P46821,Q6W2J9,Q07020,O00170,P61353,P49327,Q4G0J3,Q5F1R6,P57081,O43709,P26196,Q6PGP7,Q96F07,Q06124,P49917,P26639,P42345,O00203,P60866,Q00610,Q5SRE5,Q92917,Q9BV10,Q13555,P22681,P61254,P63241 88 +Abnormality of the outer ear 0.2861793391892457 3.393441670244486 0.000690202559108 0.9586219064911208 0.0542032328029841 360 Q2VPK5,Q3SYG4,P62847,O60701,P10589,O75909,Q12873,Q13535,Q9H3P2,Q9NVI1,Q9NR45,Q9NRZ9,Q9UET6,P42766,P42858,P08243,Q9Y4X0,Q96EK5,Q07864,P62854,P61313,Q08AM6,O14802,O60826,O14617,P62899,Q9BTW9,Q9BPU6,Q01433,P08708,Q9Y263,O43776,A1X283,Q9Y4A5,P27635,P26640,P78527,Q8IWS0,Q7Z6Z7,O60231,P62266,Q9HC07,Q15042,Q9UID3,Q96C86,Q7LBC6,Q8IY37,Q93008,A5YKK6,O43933,P21359,Q01968,Q9P2D1,Q14999,P62081,Q14839,Q9Y296,P18074,Q96N67,O15111,P28482,P46821,Q6W2J9,Q07020,O00170,P61353,Q4G0J3,Q5F1R6,P57081,O43709,P26196,Q6PGP7,Q06124,P49917,O43505,P26639,O00203,P60866,Q00610,Q5SRE5,Q92917,Q9BV10,Q16512,Q13555,P22681,P31939,P61254,P63241 88 +Absent earlobe 0.97493285586392 3.33518993677522 0.0008524115528474 0.9804318368358552 0.0542032328029841 2 Q13535 1 +Abnormal location of ears 0.2949153211455121 3.223070499414618 0.0012682433539412 0.9971319404734404 0.0542032328029841 258 P36507,Q2VPK5,Q3SYG4,P68400,P08708,P62847,Q9Y263,Q5TBB1,Q93008,A5YKK6,Q07020,O43933,P61353,P21359,Q01968,O75909,Q12873,Q13535,O43776,A1X283,Q9H3P2,Q4G0J3,Q9P2D1,Q9Y3Z3,Q9Y4A5,Q9NRZ9,O43709,P62081,P26196,P42766,Q14839,Q6PGP7,P46777,P27635,P26640,P78527,Q06124,P49917,Q96EK5,O43505,Q07864,Q7Z6Z7,O00203,P62854,P60866,P61313,Q08AM6,Q5SRE5,O14802,Q92917,O15111,P47897,Q05639,O60826,O14617,O60231,P28482,P62266,Q13555,P22681,P60953,P31939,Q9HC07,Q15042,P62899,P61254,P63241,Q9Y223,P46821,Q96C86,Q6W2J9 71 +Abnormal scalp morphology 0.3597563085102627 3.152978039334933 0.0016161396453144 0.9994250819487176 0.0598278753155478 127 P08708,Q9UPP1,Q07020,P62847,P61353,O43933,P51532,P21359,Q01968,O75909,P49327,Q13535,Q9H3P2,Q9NR45,P62081,P42766,P46778,P18074,Q06124,P49917,Q96EK5,Q7Z6Z7,P26639,P62854,P60866,O00443,P61313,Q96N67,Q08AM6,O14802,Q9BV10,O60826,P28482,P29372,P22681,Q15042,P62899,P61254,P63241,Q9UID3 40 +Abnormality of the palpebral fissures 0.2983563421027136 3.1133151755806874 0.0018499834088911 0.9998048763443954 0.0598278753155478 238 Q2VPK5,Q3SYG4,Q9UPP1,O60701,Q93008,O43933,P10589,P21359,Q01968,O75909,A1X283,Q13535,O43776,P53618,Q9H3P2,Q4G0J3,Q9P2D1,Q5F1R6,Q9Y4A5,P42695,Q9NVI1,O43709,P26196,Q14839,P42858,Q14204,Q6PGP7,Q00534,Q9Y296,P27635,Q96F07,Q8IWS0,Q06124,Q9Y4X0,Q96EK5,P49917,Q7Z6Z7,P42345,O00203,Q00610,Q08AM6,O14802,Q92917,Q9HCK8,O60826,Q13555,O14646,P28482,P22681,P63241,Q6W2J9,Q9BTW9,Q9BPU6,Q01433 54 +Adenomatous colonic polyposis 0.9200000000000016 3.078782587636278 0.0020784830348778 0.9999321370521982 0.0602886650328415 3 Q07864,P28340 2 +Abnormality of globe location 0.2828405019544059 3.0781746722825054 0.0020827279808481 0.999933455730371 0.0602886650328415 293 Q2VPK5,P62847,O15357,O60701,O75909,Q12873,Q9H3P2,Q9NVI1,Q9NRZ9,P42766,P42858,P40763,P46777,Q92908,Q96EK5,P62854,Q9UBB6,P61313,Q08AM6,O14802,Q9HCK8,P47897,Q05639,O60826,O14617,Q06787,P60953,P62899,Q9Y223,Q9BTW9,Q9BPU6,P36507,P08708,P68400,O43776,A1X283,P28340,Q9Y4A5,P35573,P78527,Q8IWS0,Q9BUK6,Q7Z6Z7,Q15477,Q15042,Q9UID3,Q96C86,Q8IY37,Q93008,A5YKK6,O43933,P21359,Q01968,Q9P2D1,P62081,Q14839,Q9Y296,P18074,P28482,P29372,Q07020,P61353,Q4G0J3,Q5F1R6,P57081,P26196,Q6PGP7,Q06124,P49917,P26639,P42345,P60866,Q92917,Q16512,P22681,P61254,P63241 77 +Abnormal thyroid hormone level 0.9051029543419862 3.032582008129705 0.0024247120356903 0.9999863090978328 0.0628294957261672 2 Q93008 1 +Laryngeal dystonia 0.9048045359594116 3.0312645712112616 0.0024353175408622 0.9999869643336284 0.0628294957261672 2 O75569 1 +Abnormality of the cervical spine 0.355770670179442 3.0163451726246366 0.0025584183718185 0.9999926227303576 0.0628294957261672 107 P08708,Q3SYG4,Q07020,P62847,O15357,Q8IY37,P61353,P21359,Q00535,Q9NVI1,Q9NR45,Q14999,P62081,P42766,P18074,Q06124,Q9Y4X0,Q96EK5,Q07864,P62854,P60866,P61313,Q99575,Q5SRE5,O14802,Q92917,O60826,P28482,P22681,P61254,P62899 31 +Hypertelorism 0.2997844020656305 2.9988041448607023 0.0027104147944387 0.9999963475722669 0.0633046397642923 219 P36507,Q2VPK5,P08708,P68400,Q07020,P62847,O15357,Q8IY37,P61353,O43933,P21359,O75909,Q12873,A1X283,O43776,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,Q9NVI1,P57081,Q9NRZ9,P62081,P26196,P42766,P42858,Q14839,P40763,P46777,Q6PGP7,Q9Y296,P18074,Q92908,Q06124,Q96EK5,P49917,Q7Z6Z7,P26639,P42345,P62854,P60866,Q9UBB6,P61313,Q08AM6,O14802,Q15477,Q9HCK8,O60826,P28482,P29372,P22681,P60953,P61254,P62899,P63241,Q9Y223,Q9UID3,Q9BTW9,Q9BPU6 59 +Miosis 0.8955535660996661 2.9903192163787624 0.002786860401315 0.9999974354666477 0.0639591394590362 2 Q6XZF7 1 +Abnormal thorax morphology 0.2924753023888169 2.971811728250504 0.0029604816543318 0.9999988513888785 0.0643581243495862 240 P08708,Q9UPP1,Q07020,P62847,Q9Y263,P61353,O95352,O43933,P21359,P42356,Q01968,O43776,A1X283,Q13535,Q5F1R6,Q9P2D1,Q9Y6D5,Q14999,O43709,P62081,P26196,P42766,P42858,Q9Y5L0,Q14839,Q9Y296,P18074,Q06210,Q06124,P49917,Q9BUK6,Q7Z6Z7,P26639,P42345,P50570,P62854,P60866,O00443,P61313,Q99575,Q08AM6,O14802,Q92917,Q9BV10,Q13501,O60333,O60826,P28482,P22681,P62899,Q6W2J9,P46821,Q9BTW9,Q9BPU6,Q8NCE2 55 +Abnormality of facial skeleton 0.2636392014618033 2.9568845922800757 0.0031076440895776 0.9999994186328512 0.0643581243495862 338 P08708,Q2VPK5,Q07020,P62847,Q9Y263,O00170,P61353,A5YKK6,O95352,O43933,O15357,P21359,P42356,Q01968,O75909,O43776,Q13535,A1X283,P28340,Q4G0J3,Q5F1R6,Q9P2D1,Q00535,Q9Y4A5,Q9H3P2,Q86Y56,Q9NVI1,P57081,Q9NRZ9,Q14999,O43709,P62081,P26196,P42766,P42858,P08243,P35573,Q9Y296,P27635,P26640,P67870,P18074,Q06210,Q06124,Q9Y4X0,Q96EK5,Q9BUK6,P49917,Q07864,Q7Z6Z7,P57678,P26639,P62854,P60866,O00443,P61313,Q08AM6,Q5SRE5,O14802,Q13315,Q92917,Q9BV10,O15111,O60826,O14617,P28482,P22681,P50851,Q9HC07,Q15042,P62899,P61254,P63241,Q9BTW9,Q9BPU6 75 +Abnormal thumb morphology 0.3515262530234874 2.9549707181444154 0.0031269872808794 0.999999468409576 0.0643581243495862 117 P08708,Q9UPP1,Q07020,P62847,O15357,P61353,Q93008,A5YKK6,Q9H3P2,Q9P2D1,Q9NVI1,P57081,O43709,P62081,P26196,P42766,P42858,Q9Y296,P49917,Q7Z6Z7,P62854,P60866,P61313,Q08AM6,Q69YN2,Q92917,Q9BV10,P61254,P62899,Q6W2J9,Q9BPU6 31 +Proportionate tall stature 0.8833184124142024 2.935851868053087 0.0033263312345452 0.9999997886907086 0.0643581243495862 2 P21359 1 +Long penis 0.8833184124141991 2.9358518680530667 0.0033263312345455 0.9999997886907086 0.0643581243495862 2 O14802 1 +Fractures of the long bones 0.8913746916844955 2.9327871086891397 0.0033593415641282 0.9999998186306605 0.0643581243495862 4 Q9BTW9,Q13126 2 +Brain neoplasm 0.8880702409689802 2.917946953277355 0.0035234428532593 0.999999915146849 0.0643581243495862 4 Q07864,P28340 2 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2876811592829076 2.903663051205182 0.0036882486425775 0.9999999604359152 0.0646916007156283 247 Q2VPK5,P08708,Q07020,P62847,O15357,Q9Y263,P61353,O43933,P21359,P42356,Q01968,Q00535,A1X283,Q13535,P28340,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,Q9NVI1,P57081,Q9NRZ9,Q14999,O43709,P62081,P26196,P42766,P42858,P08243,Q14839,Q9Y296,P27635,P26640,P18074,Q06124,Q9Y4X0,Q9BUK6,P49917,Q07864,Q7Z6Z7,P57678,P26639,P62854,P60866,P61313,Q08AM6,O14802,Q92917,Q9BV10,O15111,O60826,P28482,P22681,Q15042,P62899,P61254,P63241,Q6W2J9,Q9BTW9,Q9BPU6 60 +Abnormal b cell subset distribution 0.8731721874067426 2.8904104027386297 0.0038473918614063 0.9999999810648958 0.0655781292985262 2 P50851 1 +Uncombable hair 0.8707848403461615 2.8796820327312327 0.0039807642117906 0.999999989790146 0.0655781292985262 2 Q15477 1 +Parietal bossing 0.8666069829901453 2.860874006876068 0.004224749112841 0.9999999967023362 0.0658507377007854 2 O14802 1 +Trichorrhexis nodosa 0.8710447761194049 2.8605760319288533 0.0042287214088561 0.9999999967624648 0.0658507377007854 3 P18074,Q15477 2 +Albinism 0.8642196359295664 2.8501074485405424 0.0043704461984455 0.999999998320976 0.0658507377007854 2 O14617 1 +Macrocephaly at birth 0.8639212175469946 2.848760649665945 0.0043889885583086 0.9999999984592018 0.0658507377007854 2 Q8NCE2 1 +T cell lymphoma 0.8651637213443399 2.8143522740701283 0.0048875635844733 0.9999999998471568 0.0691605239729318 4 P52701,Q07864 2 +Aplasia of the semicircular canal 0.8552670844524011 2.8096085862650195 0.0049601783500634 0.9999999998908436 0.0697600692952522 2 Q06124 1 +Optic disc hypoplasia 0.8612938487788174 2.796725252383935 0.0051623411863017 0.999999999957246 0.0712594035535486 4 P10589 1 +Morphological abnormality of the vestibule of the inner ear 0.8555223880597029 2.7901836785448237 0.0052678147052482 0.9999999999737842 0.0717271383217048 3 Q06124,Q9P2D1 2 +Wide nasal bridge 0.3190225759534285 2.7801926594580437 0.0054326657093592 0.9999999999877954 0.0722215761304738 167 P08708,P68400,Q07020,P62847,P61353,Q93008,O43933,O75909,Q12873,A1X283,Q4G0J3,Q9H3P2,Q9Y4A5,O43709,P62081,P26196,P42766,P42858,P40763,P46777,Q6PGP7,Q9Y296,P27635,P78527,P18074,Q06124,P49917,Q96EK5,Q7Z6Z7,O00203,P62854,P60866,O00443,P61313,Q5SRE5,Q15477,O60826,P28482,P29372,P60953,Q15042,P62899,P61254,Q9Y223,Q9BPU6,Q6P2Q9 46 +Hypoplastic ischia 0.8454192778275096 2.764832123207259 0.0056952097449562 0.9999999999963892 0.0739662163423098 2 Q14999 1 +Abnormality of the ischium 0.8454192778275096 2.764832123207259 0.0056952097449562 0.9999999999963892 0.0739662163423098 2 Q14999 1 +Periventricular nodular heterotopia 0.8483701811422906 2.7575506401570458 0.005823619221601 0.99999999999801 0.0748368360169322 3 Q9Y6D5 1 +Thin vermilion border 0.3328845777451319 2.7570740830089067 0.0058321136513854 0.9999999999980868 0.0748368360169322 140 P68400,Q15436,Q93008,P51532,P21359,Q01968,A1X283,Q9Y4A5,P42695,Q9UET6,P26196,P42858,Q00534,P35573,P27635,Q9Y296,P78527,Q92908,Q9Y4X0,P49917,Q7Z6Z7,P42345,O00203,Q00610,Q08AM6,O14802,Q9BV10,Q06787,P28482,P62266,P29372,P31939,P60953,Q92974,Q15042,Q7LBC6,P63241,Q9Y223,Q9UID3,Q96C86,Q9BPU6 41 +Abnormality of the breast 0.3407467081388009 2.7522435997104213 0.0059188474975253 0.9999999999987208 0.0750563696807541 111 O00170,Q8IY37,Q93008,P31751,P42771,P21359,P49327,A1X283,Q13535,P28340,Q9P2D1,Q9Y4A5,P52701,P26196,P18074,Q8IWS0,Q06124,Q9Y4X0,Q96EK5,Q07864,P26639,Q08AM6,Q5SRE5,O14802,Q13315,Q9BV10,O96017,O60826 28 +Ankyloblepharon 0.8516975732594843 2.7338481378144173 0.0062598908466551 0.9999999999997372 0.0768267087076799 5 O75569,P18074,O15111 3 +Wide nasal ridge 0.8449527268284636 2.7218888085199517 0.0064909978396112 0.9999999999999102 0.0775861250794462 4 O14802 1 +Abnormal hair morphology 0.2651168202831435 2.703725134891508 0.0068566981429527 0.9999999999999836 0.0783043603529173 355 Q2VPK5,Q3SYG4,P62847,O60701,P51532,O75909,Q00535,Q13535,Q13126,Q9H3P2,Q9NR45,P42766,P42858,P40763,Q9Y4X0,Q96EK5,P62854,O00443,P61313,Q08AM6,O14802,O60826,O14617,P62899,Q9BTW9,Q9BPU6,P08708,Q9Y263,P42771,Q9Y4A5,P46778,P27635,P26640,O00217,Q8IWS0,Q9BUK6,Q7Z6Z7,Q99575,Q13315,Q15477,O14646,P62266,Q15042,Q9UID3,Q9UPP1,Q8IY37,Q93008,O43933,P21359,Q01968,P53618,Q9P2D1,Q14999,P62081,Q9Y296,P18074,Q96N67,O75182,P28482,P29372,P46821,Q6W2J9,Q07020,O00170,P61353,P49327,Q7KZN9,Q4G0J3,Q5F1R6,P26196,Q6PGP7,Q96F07,Q06124,P49917,P26639,P42345,O00203,P60866,P50747,Q5SRE5,Q69YN2,Q9BV10,Q13555,P22681,P40818,P61254,P63241 87 +Autosomal dominant germline de novo mutation 0.835172345871659 2.697002314247996 0.0069966784092678 0.9999999999999916 0.079496742615647 3 Q9HCK8 1 +Abnormal external genitalia 0.2686377318359212 2.681703993518875 0.0073248240629317 0.999999999999998 0.0820131393259813 298 Q2VPK5,Q3SYG4,P08708,Q9UPP1,P62847,O15357,Q8IY37,Q93008,Q07020,O00170,O43933,P61353,P51532,P42771,P21359,Q01968,P49327,Q13535,P28340,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,Q14999,O43709,P62081,P26196,P42766,P42858,Q14839,Q6PGP7,Q01844,Q9Y296,P27635,P78527,Q8IWS0,P18074,Q06124,P49917,Q96EK5,O43505,Q07864,Q7Z6Z7,P26639,P42345,P50570,P62854,P60866,O00443,P61313,Q08AM6,O14802,Q13315,Q9BV10,O15111,O96017,O60826,P28482,P29372,P22681,P31939,Q15042,P62899,Q7LBC6,P61254,P63241,Q6W2J9,Q9BTW9,Q9BPU6,Q8NCE2 70 +Gingivitis 0.8295988739082637 2.6713030307640815 0.0075557401899204 0.9999999999999992 0.0833842810911555 3 Q01968 1 +Slanting of the palpebral fissure 0.2929172028620303 2.666239475933435 0.0076705032020414 0.9999999999999996 0.0840475802161927 207 Q2VPK5,Q3SYG4,Q9UPP1,Q93008,O43933,P10589,P21359,Q01968,O43776,A1X283,Q13535,P53618,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,P42695,Q9NVI1,P26196,Q14839,P42858,Q14204,Q6PGP7,Q00534,Q9Y296,Q96F07,Q06124,Q9Y4X0,Q96EK5,P49917,Q7Z6Z7,P42345,O00203,Q00610,Q08AM6,O14802,Q9HCK8,O60826,O14646,P28482,P22681,P63241,Q9BTW9,Q9BPU6,Q01433 45 +Cutaneous syndactyly of toes 0.8326722789328506 2.6652166724319017 0.0076938733270504 0.9999999999999996 0.0841038807054111 4 Q9H4L7,P27635 2 +Abnormal jaw morphology 0.2676263554228647 2.657689358859859 0.007867837682705 1.0 0.0849984431623381 299 Q2VPK5,P08708,Q07020,P62847,Q9Y263,O00170,P61353,O95352,O43933,P21359,P42356,Q01968,Q00535,O75909,Q13535,A1X283,O43776,Q9H3P2,P28340,Q9P2D1,Q5F1R6,Q9Y4A5,Q9NVI1,P57081,Q9NRZ9,Q14999,O43709,P62081,P26196,P42766,P42858,P08243,Q9Y296,P27635,P26640,P67870,P18074,Q06210,Q06124,Q9Y4X0,Q96EK5,Q9BUK6,P49917,Q07864,Q7Z6Z7,P57678,P26639,P62854,P60866,O00443,P61313,Q08AM6,Q5SRE5,O14802,Q92917,Q9BV10,O15111,O60826,O14617,P28482,P22681,Q15042,P62899,P61254,P63241,Q9BTW9,Q9BPU6 67 +Patchy changes of bone mineral density 0.8296877389711406 2.6513872466032296 0.0080161873328199 1.0 0.0859148984013981 4 Q13126 1 +Decreased circulating igg subclass level 0.8239461987127854 2.645159621636356 0.0081652389377304 1.0 0.0859148984013981 3 Q13315 1 +Abnormality of digestive system morphology 0.2776031013304683 2.641545543541478 0.0082528710533837 1.0 0.0859148984013981 249 P08708,Q07020,P62847,P61353,Q93008,O43933,P20585,P42771,Q01968,P49327,P28340,Q5F1R6,Q86Y56,Q9P2D1,Q9Y6D5,Q9NVI1,P57081,Q9NRZ9,Q9UET6,P52701,O14965,O43709,P62081,P14174,P26196,P42766,Q14839,Q9Y5L0,P41252,P40763,P46777,Q6PGP7,Q01844,Q9Y6B6,P18074,P49917,Q96EK5,Q07864,P42345,P50570,P62854,P60866,O00443,P61313,Q08AM6,Q9BV10,Q15477,P46821,O96017,O60826,P28482,P29372,P22681,P50851,P61254,P62899,Q6W2J9,Q9UID3,Q7LBC6,Q8NCE2,P54277 61 +Wheezing 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Absent outer dynein arms 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Respiratory insufficiency due to defective ciliary clearance 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Abnormal atrial arrangement 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Chronic bronchitis 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Abnormal respiratory motile cilium morphology 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Nasal congestion 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Absent shortened dynein arms 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Abnormal respiratory motile cilium physiology 0.8182632050134276 2.6401100805185527 0.0082879102078088 1.0 0.0859148984013981 2 Q86Y56 1 +Abnormal intestine morphology 0.2949780309979454 2.617868181771261 0.0088480977858083 1.0 0.0877856208079889 197 P08708,Q07020,P62847,P61353,Q93008,O43933,P20585,P42771,Q01968,P49327,P28340,Q5F1R6,Q86Y56,Q9P2D1,Q9NVI1,Q9NRZ9,Q9UET6,P52701,O14965,O43709,P62081,P14174,P42766,Q9Y5L0,P40763,P46777,Q6PGP7,Q01844,Q9Y6B6,P18074,Q92908,P49917,Q96EK5,Q07864,P42345,P62854,P60866,O00443,P61313,Q9Y620,Q9BV10,Q15477,O96017,O60826,P22681,P50851,P61254,P62899,Q6W2J9,Q9UID3,Q7LBC6,P54277 52 +Malignant hyperthermia 0.821920122924862 2.6152910257707767 0.0089151457065299 1.0 0.0877856208079889 4 P50570,Q8NCE2 2 +Abnormal hemidiaphragm morphology 0.8122948373619809 2.6124513393743634 0.008989548852738 1.0 0.0877856208079889 2 Q92908 1 +Weakness of long finger extensor muscles 0.8122948373619758 2.6124513393743296 0.0089895488527389 1.0 0.0877856208079889 2 Q13501 1 +Panhypogammaglobulinemia 0.8251310526839479 2.6106919649700115 0.0090359242795132 1.0 0.0877856208079889 5 Q6PGP7,P18074,Q15477 3 +Abnormal hand morphology 0.3313681549604614 2.5996642049342324 0.0093315022186608 1.0 0.0893007841034524 121 Q2VPK5,P08708,Q9UPP1,Q07020,P62847,O00170,P61353,Q93008,O43933,P51532,P42356,P21359,Q00535,Q9H3P2,Q9P2D1,Q9NVI1,Q9UET6,Q14999,P62081,P42766,P08243,P27635,P78527,Q8IWS0,P42345,P62854,P60866,O00443,P61313,Q08AM6,O14802,Q9BV10,O60826,P28482,P61254,P62899,Q6W2J9 37 +Abnormality of the neck 0.3000880860032968 2.5915620687274137 0.0095541305257993 1.0 0.0897003251771202 180 O75569,P08708,Q3SYG4,Q9UPP1,Q07020,P62847,O15357,Q8IY37,P61353,O43933,P21359,Q00535,A1X283,Q9H3P2,Q9P2D1,Q9NVI1,Q9NR45,Q14999,O43709,P62081,P42766,P27635,P18074,Q9H269,Q9Y4X0,Q96EK5,P04350,Q06124,Q07864,Q7Z6Z7,P62854,P60866,O00443,P61313,Q99575,Q08AM6,Q5SRE5,Q92917,Q9BV10,Q13501,O60826,P28482,P22681,Q15042,P62899,P61254,Q9UID3,Q6W2J9 48 +Abnormal right ventricular function 0.8105895257124596 2.583068688696815 0.0097925824339704 1.0 0.090346365535811 3 Q9UER7 1 +Broad alveolar ridges 0.814274541327193 2.579615537712209 0.0098910365222328 1.0 0.0910725578384437 4 Q08AM6 1 +Antinuclear antibody positivity 0.8109976253207911 2.564280395538842 0.0103389982683184 1.0 0.0935172529642212 4 P53621,Q9Y5L0 2 +Gastritis 0.8127741937920983 2.5528152386351968 0.0106856163131077 1.0 0.0949763931644815 5 P49327,P50851,Q15477 3 +Recurrent staphylococcus aureus infections 0.7985675917636512 2.548495785298321 0.0108188594142728 1.0 0.0957915517812681 2 P40763 1 +Recurrent staphylococcal infections 0.7985675917636512 2.548495785298321 0.0108188594142728 1.0 0.0957915517812681 2 P40763 1 +Long thorax 0.7979707549985016 2.545704320072512 0.010905752025057 1.0 0.0963759273785214 2 Q6W2J9 1 +Chronic rhinitis 0.8058806966909332 2.540280945933848 0.011076345436932 1.0 0.0973241552391761 4 Q9BV10,Q86Y56 2 +Neonatal insulin dependent diabetes mellitus 0.804525525773197 2.5339139807871134 0.0112796416854135 1.0 0.09779357559164 4 P40763,A5YKK6 2 +Bloodstream infectious agent 0.7988059701492545 2.5279197587295403 0.0114740572460105 1.0 0.0978370167760569 3 P17812,P29144 2 +Increased circulating igg level 0.7988059701492549 2.5279197587295403 0.0114740572460105 1.0 0.0978370167760569 3 P49327,P29144 2 +Spontaneous abortion 0.7984997541378519 2.5264819730583343 0.0115211300998741 1.0 0.0980571460345373 3 Q8NCE2 1 +Abnormality of upper lip vermillion 0.32419803401926 2.518941115131916 0.0117708340026942 1.0 0.0999978954961856 132 P68400,Q15436,Q9Y263,Q93008,P46109,P51532,Q01968,Q9BSJ2,A1X283,Q4J6C6,Q9Y4A5,P42695,P57081,Q9UET6,Q15058,P62081,Q13045,Q00534,P35573,P27635,Q08J23,Q96F07,P78527,Q9Y4X0,Q96KP1,Q7Z6Z7,P42345,O00203,Q9H7D7,Q00610,O14802,Q9BV10,P46821,Q05639,Q12830,P28482,Q6PJG6,P29372,P31939,P60953,Q92974,P63241,Q9Y223,Q9UID3,Q96C86,Q14738,Q7LBC6 47 +Small anterior fontanelle 0.7950021652021151 2.5100429222431764 0.0120716487566676 1.0 0.1007001399892535 3 Q13535 1 +Bloody diarrhea 0.7978713079557549 2.502584150690081 0.0123290312108497 1.0 0.1014013933115624 4 Q9UER7,Q15477 2 +2 3 toe cutaneous syndactyly 0.7932802305308881 2.5019383483062425 0.0123515431682492 1.0 0.1014013933115624 3 P27635 1 +Abnormal morphology of the great vessels 0.2942444455598595 2.50165844720694 0.0123613115163889 1.0 0.1014013933115624 183 Q2VPK5,P08708,Q07020,P62847,P61353,Q93008,O43933,P51532,P21359,A1X283,Q86Y56,Q9P2D1,Q9Y4A5,Q9Y6D5,Q9NVI1,O43709,P62081,P26196,P42766,P42858,Q14839,Q6PGP7,P46777,Q9UBS4,Q9Y296,P27635,Q92908,Q9Y4X0,Q06124,Q7Z6Z7,P62854,P60866,P61313,Q08AM6,Q9BV10,Q15477,O15111,O60826,P57076,Q06787,P28482,P22681,P61254,P62899,Q7LBC6,Q6W2J9,P46821,Q9BPU6 48 +Thin upper lip vermilion 0.3387331295307258 2.4967812745189963 0.0125326232420648 1.0 0.1020422788558564 103 P68400,Q15436,Q93008,P51532,Q01968,A1X283,Q9Y4A5,P42695,Q9UET6,Q00534,P35573,P27635,P78527,Q9Y4X0,Q7Z6Z7,P42345,O00203,Q00610,O14802,Q9BV10,P28482,P29372,P31939,P60953,Q92974,P63241,Q9Y223,Q9UID3,Q96C86,Q7LBC6 30 +Hypothalamic hamartoma 0.784541927782739 2.4826581158663497 0.0130406179139876 1.0 0.104127305853789 2 Q9H269 1 +Abnormal hair pattern 0.3237282037369418 2.4806864484308044 0.0131129664850595 1.0 0.104127305853789 127 P08708,Q9UPP1,Q07020,P62847,P61353,O43933,P51532,P21359,O75909,Q9H3P2,Q9NR45,P62081,P26196,P42766,P42858,Q9Y296,Q06124,P49917,Q7Z6Z7,P62854,P60866,O00443,P61313,Q96N67,Q9BV10,O60826,P28482,P29372,P22681,Q15042,P62899,P61254,Q9UID3,Q9BPU6 34 +B cell lymphoma 0.7982105284211749 2.4648077109942577 0.0137086798033045 1.0 0.1063094351669244 6 Q9UDY8,Q13315 2 +Abnormal mean corpuscular hemoglobin concentration 0.7841053313013551 2.458629470038008 0.0139468478160793 1.0 0.1063094351669244 3 P18074 1 +Defective dna repair after ultraviolet radiation damage 0.7841053313013551 2.458629470038008 0.0139468478160793 1.0 0.1063094351669244 3 P18074 1 +Increased mean corpuscular hemoglobin concentration 0.7841053313013551 2.458629470038008 0.0139468478160793 1.0 0.1063094351669244 3 P18074 1 +Tiger tail banding 0.7841053313013551 2.458629470038008 0.0139468478160793 1.0 0.1063094351669244 3 P18074 1 +Numerous pigmented freckles 0.7841053313013551 2.458629470038008 0.0139468478160793 1.0 0.1063094351669244 3 P18074 1 +Concave nail 0.7841053313013551 2.458629470038008 0.0139468478160793 1.0 0.1063094351669244 3 P18074 1 +Low set nipples 0.7841053313013551 2.458629470038008 0.0139468478160793 1.0 0.1063094351669244 3 P18074 1 +Buphthalmos 0.7764889630449983 2.422516624816267 0.0154134204910358 1.0 0.1139801969973228 3 A1X283 1 +Abnormality of the lower urinary tract 0.2749182131612857 2.4174929836256687 0.0156278352819674 1.0 0.1139801969973228 229 P08708,Q07020,P62847,O00170,Q8IY37,Q93008,P61353,O43933,P51532,P53618,P38935,Q13535,P26358,Q9H3P2,O75165,Q9P2D1,Q9Y4A5,P42695,Q9NVI1,Q14999,O43709,P62081,P26196,P42766,Q14839,Q6PGP7,Q00534,P27635,Q9Y3I1,Q06124,P49917,Q96EK5,Q07864,Q7Z6Z7,Q9NZJ4,P42345,P50570,P62854,P60866,P61313,Q08AM6,O95248,O14802,Q9BV10,Q13501,O60826,P29372,P61254,P62899,Q6W2J9,Q9BTW9,Q7LBC6,Q8NCE2 53 +Uric acid nephrolithiasis 0.7702178454192802 2.4149053558955207 0.015739298826638 1.0 0.1139801969973228 2 P00492 1 +Macroscopic hematuria 0.7702178454192802 2.4149053558955207 0.015739298826638 1.0 0.1139801969973228 2 P00492 1 +Decreased urine output 0.7702178454192663 2.4149053558954536 0.0157392988266409 1.0 0.1139801969973228 2 O43772 1 +Oliguria 0.7702178454192663 2.4149053558954536 0.0157392988266409 1.0 0.1139801969973228 2 O43772 1 +Agenesis of maxillary incisor 0.7666368248284012 2.39788592455352 0.0164899998501359 1.0 0.117935456292523 2 Q6W2J9 1 +Broad clavicles 0.7663384064458254 2.396466172264943 0.0165540214313621 1.0 0.118027358366111 2 A1X283 1 +Chronic noninfectious lymphadenopathy 0.7750281888513835 2.394191644061171 0.0166570428903667 1.0 0.1183958996198178 4 P49327 1 +Aplasia hypoplasia of the extremities 0.2872475051691398 2.389850898791425 0.0168552139918336 1.0 0.1194365860978383 192 P08708,Q07020,P62847,O15357,P61353,Q93008,P51532,A1X283,Q13535,Q9H3P2,Q9P2D1,Q9Y4A5,Q9NVI1,Q9NR45,Q9UET6,Q14999,P62081,P26196,P42766,P42858,Q14839,Q14204,Q9Y296,P27635,Q8IWS0,Q9Y4X0,Q96EK5,P49917,Q07864,Q7Z6Z7,P42345,P62854,P60866,O00443,P61313,Q99575,Q08AM6,O14802,Q9BV10,O15111,O60826,Q13555,P28482,P61254,P62899,Q6W2J9,Q9BPU6 47 +Polysplenia 0.7695025679864678 2.389262548829261 0.0168822329829041 1.0 0.1194365860978383 3 Q86Y56 1 +Abnormal aortic morphology 0.3205856114227859 2.3881611971877197 0.0169329129217399 1.0 0.1194365860978383 114 P08708,Q07020,P62847,Q5TBB1,P61353,P21359,Q9P2D1,Q9Y3Z3,Q9Y4A5,Q9Y6D5,Q9NVI1,O43709,P62081,P26196,P42766,P42858,Q14839,P46777,Q9UBS4,Q9Y296,Q92908,Q06124,Q7Z6Z7,P62854,P60866,P61313,Q06787,P28482,P61254,P62899,Q6W2J9,P46821,Q9BPU6 33 +Subependymal cysts 0.7689285656286031 2.3865249419116763 0.0170084535963259 1.0 0.1197862541066438 3 O43933 1 +Severe varicella zoster infection 0.766865671641793 2.376679489790524 0.0174692599389176 1.0 0.1217306587586514 3 P17812,O95394 2 +Abnormal corpus callosum morphology 0.2555668266249492 2.37374375066333 0.0176087662340187 1.0 0.1223331907191694 310 P10589,P51532,Q00535,Q9H3P2,Q9Y6D5,Q9H1B7,P42695,Q9NVI1,Q9NR45,Q9ULK4,Q9UPN3,Q8N8R5,P42858,P08243,Q00534,Q96EK5,Q9NZJ4,O00443,Q9UBB6,Q08AM6,O14802,P47897,Q05639,Q9NW08,P60953,Q8NC96,Q9BTW9,Q9BPU6,Q01433,P36507,Q9Y263,Q5TBB1,O43776,A1X283,Q9BSJ2,Q9Y3Z3,Q9Y4A5,Q14746,Q13045,Q14204,P26640,P78527,Q9NZB8,Q7Z6Z7,O00429,O43924,Q12830,O60231,Q6PJG6,Q6NXR4,Q9C0E8,Q15042,Q9UID3,Q96C86,Q14738,Q7LBC6,Q93008,A5YKK6,Q08209,O43933,P21359,P48651,Q6DN90,Q15058,Q13885,O60610,P54136,Q9Y296,Q08J23,P67870,P18074,Q96KP1,Q9H7D7,Q96N67,O75182,P29372,P46821,Q6W2J9,Q2M389,O95352,P57081,P07814,P26196,Q96F07,Q96F86,P49917,O43505,O60524,O94903,P26639,P42345,Q00610,Q5SRE5,Q69YN2,Q92917,Q9BV10 96 +Chronic sinusitis 0.7736517781255752 2.3670789737175366 0.0179291065597122 1.0 0.1238023775792207 5 Q86Y56,P57076,O95394 3 +Cardiac diverticulum 0.7694105815480424 2.346715926624758 0.018939688544481 1.0 0.1290528556214046 5 P52701,P54277 2 +Abnormal circulating ceruloplasmin concentration 0.7538048343777852 2.336633051446245 0.0194582723626539 1.0 0.1307261775890001 2 Q14746 1 +Lactose intolerance 0.7578193612761297 2.333378658604588 0.0196282803545111 1.0 0.1308457475077455 3 P42345 1 +Decreased head circumference 0.2409870481440102 2.330824461806634 0.0197626176944647 1.0 0.1313011230645798 478 P00374,Q2VPK5,P62847,O60701,P51532,Q00535,Q13535,Q9H3P2,Q9Y6D5,P42695,Q9NVI1,Q9NR45,Q9ULK4,Q9UPN3,Q8N8R5,P42766,P42858,P08243,P46777,Q00534,Q92908,Q96EK5,Q07864,P62854,Q9UBB6,P61313,Q08AM6,O95248,P47897,Q05639,O14617,Q15003,P60953,Q8NC96,P62899,Q9BTW9,Q9BPU6,Q01433,P08708,Q9Y263,O43772,P42356,O43776,Q9Y4A5,Q14746,Q15021,Q14204,P27635,P26640,O00217,P78527,Q8IWS0,Q7Z6Z7,P62266,Q9HC07,Q15042,Q9UID3,Q96C86,Q9NPL8,Q9UPP1,Q8IY37,A5YKK6,O43933,P21359,P53618,Q9P2D1,Q8IUX1,P62081,Q9Y296,P67870,P18074,P04350,P57678,O15111,O75182,P28482,P46821,Q6W2J9,Q2M389,Q07020,P61353,Q7KZN9,Q13144,Q4G0J3,Q5F1R6,P57081,O43709,P07814,P26196,P41252,Q96IJ6,Q96F07,Q96F86,P49917,O43505,O60524,O94903,P26639,O00203,P60866,Q00610,Q5SRE5,Q69YN2,Q92917,Q9BV10,P61254,P63241 107 +Aplasia hypoplasia involving the skeleton 0.2524718622516719 2.3304575434918484 0.0197819814719018 1.0 0.1313011230645798 316 P08708,Q2VPK5,Q07020,P62847,Q9Y263,P61353,Q93008,O15357,O43933,P21359,P42356,Q01968,P51532,A1X283,Q13535,P28340,Q00535,Q5F1R6,Q9H3P2,Q9P2D1,Q9Y4A5,Q9NVI1,P57081,Q9NRZ9,Q9UET6,Q9NR45,Q14999,O43709,P62081,P26196,P42766,P42858,Q14839,P08243,Q14204,Q9Y296,P27635,P26640,P18074,Q8IWS0,Q06124,Q9Y4X0,Q96EK5,Q9BUK6,P49917,Q07864,Q7Z6Z7,P57678,P26639,P42345,P62854,P60866,O00443,P61313,Q99575,Q08AM6,O14802,Q92917,Q9BV10,O15111,O60826,Q13555,P28482,P22681,Q15042,P62899,P61254,P63241,Q6W2J9,Q9BTW9,Q9BPU6 71 +Abnormal libido 0.765683607850492 2.328785175393812 0.0198704491483852 1.0 0.1315098736319956 5 Q9P2D1,P42858 2 +Epicanthus 0.2901379896062866 2.3204687877761287 0.020315531486913 1.0 0.1332320816013553 178 P36507,P08708,Q07020,P62847,P61353,O60701,A5YKK6,O43933,P10589,P21359,Q12873,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,Q9NVI1,Q9NR45,Q9NRZ9,P57081,O43709,P62081,P26196,P42766,Q14839,P46777,P27635,P18074,Q06124,P49917,Q7Z6Z7,P26639,O00203,P62854,P60866,O00443,Q9UBB6,P61313,Q5SRE5,Q9BV10,P46821,P47897,Q05639,O60231,P28482,P62266,P22681,P61254,P62899,P63241,Q9Y223,Q9UID3 51 +Ileus 0.7575395640489755 2.3103277461070664 0.0208700159395034 1.0 0.1352268232910244 4 P50336,P16930,Q01844 3 +Aplasia hypoplasia involving bones of the upper limbs 0.3056497737168427 2.309439732469483 0.0209191923696085 1.0 0.1353439472664859 152 P08708,Q07020,P62847,O15357,P61353,Q93008,P51532,A1X283,Q13535,Q9H3P2,Q9P2D1,Q9NVI1,Q9NR45,Q9UET6,Q14999,P62081,P42766,P42858,Q14204,P27635,Q8IWS0,P49917,Q96EK5,Q7Z6Z7,P42345,P62854,P60866,O00443,P61313,Q08AM6,O14802,Q9BV10,O15111,O60826,Q13555,P28482,P61254,P62899,Q6W2J9 39 +Abnormality of upper lip 0.2601498930395149 2.3005500180200227 0.0214170789840171 1.0 0.1374088808807663 276 P36507,Q9UPP1,P68400,O15357,Q15436,Q9Y263,O60701,Q8IY37,Q93008,A5YKK6,O95352,P51532,P21359,Q01968,O75909,A1X283,Q4G0J3,Q9H3P2,Q9P2D1,Q9Y4A5,P42695,P57081,Q9UET6,Q14999,O43709,P62081,P26196,P42858,Q6PGP7,P46777,Q00534,P35573,P27635,Q9Y296,P67870,Q96F07,P78527,Q9Y4X0,Q96EK5,Q7Z6Z7,P42345,O00203,Q00610,Q96N67,Q08AM6,O14802,Q9BV10,O15111,P46821,Q05639,O60826,O14617,Q13555,P28482,P29372,P22681,P31939,P60953,Q92974,Q15042,Q7LBC6,P63241,Q6W2J9,Q9Y223,Q9UID3,Q96C86,Q9BPU6,Q01433 68 +Dilation of virchow robin spaces 0.7427633542226075 2.2835942291375946 0.0223953892567112 1.0 0.1421044437980866 2 P27635 1 +Abnormal cervical spine morphology 0.7509235096999448 2.2784037407634696 0.0227025337353949 1.0 0.1436215476022657 4 O14802 1 +Aplasia hypoplasia of the proximal phalanges of the hand 0.746064012987263 2.2768049562594803 0.0227978754318805 1.0 0.1438667570003621 3 Q08AM6 1 +Ocular albinism 0.7451903964077695 2.2725868408958827 0.0230510893702 1.0 0.1444696851840859 3 O14617 1 +Synovitis 0.7436656124466794 2.2652201227673334 0.0234991748898183 1.0 0.1460647380119336 3 O14802 1 +Abnormal parietal bone morphology 0.7466032377371257 2.2574991157069695 0.0239769046820721 1.0 0.1480889438168077 4 Q08AM6,O14802 2 +Decreased lymphocyte apoptosis 0.7353028946583011 2.2475836165559886 0.0246027532364627 1.0 0.1505205579307729 2 P49327 1 +Onychomycosis 0.7397014925373191 2.246041176873853 0.0247013705388372 1.0 0.150923738139942 3 P40818,Q9Y5L0 2 +Carcinoma 0.7483001595352066 2.2447016123098633 0.024787294478948 1.0 0.1510505056633083 5 Q07864,P28340 2 +Decreased serum iron 0.7347060578931538 2.2446967416914108 0.0247876073676835 1.0 0.1510505056633083 2 Q15477 1 +Menorrhagia 0.7388532059997139 2.2419319909264885 0.0249657680814472 1.0 0.151137910970756 3 P35579 1 +Abnormal penis morphology 0.2783909046350968 2.233295741606333 0.0255294481596866 1.0 0.1531434907160394 200 Q2VPK5,Q3SYG4,P08708,Q07020,P62847,O00170,Q8IY37,Q93008,P61353,O43933,P51532,Q13535,Q9H3P2,Q9P2D1,Q9Y4A5,Q14999,O43709,P62081,P26196,P42766,Q14839,Q6PGP7,P27635,P78527,Q8IWS0,P18074,Q06124,P49917,Q96EK5,O43505,Q07864,Q7Z6Z7,P42345,P62854,P60866,P61313,Q08AM6,O14802,Q9BV10,O60826,P29372,Q15042,P62899,Q7LBC6,P61254,Q6W2J9,Q9BPU6 47 +Suicidal ideation 0.7364480833506369 2.230271648639358 0.0257294141719084 1.0 0.1539426557393172 3 P42858 1 +Bone fracture 0.7506331434871727 2.218152154340187 0.0265444597589152 1.0 0.157581136180063 7 Q9BTW9,Q13126 2 +Myeloid leukemia 0.7383151113322255 2.217266742389429 0.0266048691270479 1.0 0.157581136180063 4 Q06124,P21359 2 +Juvenile myelomonocytic leukemia 0.7383151113322255 2.217266742389429 0.0266048691270479 1.0 0.157581136180063 4 Q06124,P21359 2 +Abnormal number of granulocyte precursors 0.7284392718591359 2.214330831650011 0.0268060291864153 1.0 0.1576741434123965 2 Q07020 1 +Cerebellar dysplasia 0.7373613845059086 2.212626356008701 0.0269234164222065 1.0 0.1576741434123965 4 P42356 1 +Decreased specific antibody response to protein vaccine 0.7324032682938728 2.210629641674436 0.0270614943702915 1.0 0.1582188511155324 3 P17812 1 +Eunuchoid habitus 0.7349632099210914 2.2009481615356803 0.0277396938618932 1.0 0.1613659618977471 4 P04350,Q9P2D1 2 +Congenital malformation of the left heart 0.7336103982622946 2.1943543057407764 0.0282099481877255 1.0 0.1637784276585766 4 O60826,O14802 2 +Posterior pharyngeal cleft 0.7289552238806007 2.193853786942236 0.0282459225872675 1.0 0.1637784276585766 3 Q00653,P29372 2 +Erythema nodosum 0.722470904207688 2.1853200158160027 0.0288653908105489 1.0 0.1658232226762918 2 P50851 1 +Burkitt lymphoma 0.7224709042076884 2.1853200158160027 0.0288653908105489 1.0 0.1658232226762918 2 P49327 1 +Decreased cd4 cd8 ratio 0.7309644670050787 2.181444687765308 0.0291505413798423 1.0 0.1662023105184046 4 Q14790,P17812,O00203 3 +Non obstructive azoospermia 0.7250022678829768 2.174585467784799 0.0296611943067537 1.0 0.1662023105184046 3 Q9P2D1 1 +Hypothalamic gonadotropin releasing hormone deficiency 0.7250022678829768 2.174585467784799 0.0296611943067537 1.0 0.1662023105184046 3 Q9P2D1 1 +Increased female libido 0.7250022678829771 2.174585467784796 0.0296611943067539 1.0 0.1662023105184046 3 Q9P2D1 1 +Subcortical band heterotopia 0.7247761194029881 2.173481970970459 0.0297440613030932 1.0 0.1662023105184046 3 Q9BSJ2,P43034 2 +Agyria 0.724776119402988 2.173481970970459 0.0297440613030932 1.0 0.1662023105184046 3 Q00535,P43034 2 +Subcortical heterotopia 0.7247761194029881 2.173481970970459 0.0297440613030932 1.0 0.1662023105184046 3 Q9BSJ2,P43034 2 +Pancreatic islet cell hyperplasia 0.7238426528778916 2.1689257765086736 0.0300883194267473 1.0 0.1672631492253007 3 P53985 1 +Spastic paraparetic gait 0.7314752831400326 2.16261987806381 0.0305704280884189 1.0 0.1686057183171312 5 Q9Y3I1 1 +Recurrent sinusitis 0.7311827956989186 2.1611869282408436 0.0306809027525991 1.0 0.1688914133624581 5 Q86Y56,P50851,P57076,Q00653 4 +Diaphyseal thickening 0.7214357451191807 2.1571679923626403 0.0309925774162318 1.0 0.169998525114242 3 O15357 1 +Facial telangiectasia 0.7299163059272921 2.1549798037649777 0.0311634146757338 1.0 0.1707325794526841 5 Q9UER7,Q07864,P54132 3 +Small cerebral cortex 0.7156072814085346 2.151848570715166 0.0314092829578354 1.0 0.1713528843386471 2 Q15058 1 +Rhinitis 0.7397912199688994 2.1478880561556872 0.0317226494374645 1.0 0.1723634650824778 8 Q9BV10,Q86Y56,P57076,O95394 4 +Thyroiditis 0.738972651042608 2.143846281734781 0.0320452055892745 1.0 0.1733546860480189 8 P49327,P50851,Q9P2D1 3 +Recurrent mycobacterial infections 0.7159079290154418 2.13011118398259 0.0331624352088817 1.0 0.1772633993262705 3 Q86Y56 1 +Upper limb asymmetry 0.7096389137570884 2.122648806693045 0.0337832918414697 1.0 0.1791291094996552 2 Q15555 1 +Septic arthritis 0.709042076991935 2.1197240385199225 0.0340293245465059 1.0 0.1802264915419427 2 Q8N8R5 1 +Female infertility 0.7178262167811197 2.1170922433836443 0.0342520198715141 1.0 0.1803336158277304 4 Q86Y56,P57076,Q96RD7 3 +Abnormality of the hairline 0.362536559509321 2.1161108437469505 0.0343353814483133 1.0 0.1803336158277304 99 P08708,Q9UPP1,Q07020,P62847,P61353,O43933,P51532,P21359,O75909,Q9H3P2,Q9NR45,P62081,P42766,Q06124,P49917,Q7Z6Z7,P62854,P60866,O00443,P61313,Q96N67,Q9BV10,O60826,P28482,P29372,P22681,Q15042,P62899,P61254,Q9UID3 30 +Amyloidosis 0.7081468218442151 2.115335257965249 0.0344013834659442 1.0 0.1803336158277304 2 P49917 1 +Abnormal serum interleukin level 0.7081468218442142 2.115335257965244 0.0344013834659446 1.0 0.1803336158277304 2 P49327 1 +Degeneration of the striatum 0.719441985202741 2.1034986279626646 0.0354222050997445 1.0 0.184219427424038 5 Q5TBB1,P42858 2 +Large for gestational age 0.7261721990595822 2.0978058793786505 0.0359222969468882 1.0 0.1853574449843347 7 Q8NCE2,P31751,P42345 3 +Pectus excavatum of inferior sternum 0.7083200708241619 2.092850958232787 0.0363624612427393 1.0 0.1859014258071024 3 P21359 1 +Hypoamylasemia 0.7170357110451228 2.0916352657594093 0.0364711553265466 1.0 0.1859014258071024 5 A5YKK6 1 +Lymphoproliferative disorder 0.7080597014925414 2.0915699605303244 0.0364770020418283 1.0 0.1859014258071024 3 P50851,P17812 2 +Short digit 0.2924072667537323 2.085897287869349 0.0369879280257754 1.0 0.1872694393485292 158 P08708,Q3SYG4,Q07020,P62847,O15357,P61353,Q93008,P51532,A1X283,Q9H3P2,Q9P2D1,Q9NVI1,Q9UET6,Q14999,P62081,P26196,P42766,P42858,P46777,Q9Y296,P27635,Q8IWS0,Q06124,P49917,Q7Z6Z7,P42345,P62854,P60866,O00443,P61313,Q99575,Q08AM6,O60826,Q13555,P28482,P22681,P61254,P62899,Q6W2J9,Q96C86,Q9BPU6 41 +Abnormal renal vascular morphology 0.7196289722411979 2.083642730232381 0.0371926771455268 1.0 0.1879187510102031 6 Q08AM6,P21359 2 +Generalized hyperreflexia 0.715281597288061 2.0829786332522766 0.0372531712070507 1.0 0.1880184669344913 5 P18074,P26639 2 +Renal cortical microcysts 0.7053538368857561 2.078247728173653 0.037686548181357 1.0 0.1894685070005271 3 O43933 1 +Bronchospasm 0.718170808083342 2.076430555314007 0.0378541477052165 1.0 0.1897975790464133 6 Q9UER7,P18074 2 +Abnormal bronchus physiology 0.718170808083342 2.076430555314007 0.0378541477052165 1.0 0.1897975790464133 6 Q9UER7,P18074 2 +Cerebellar hypoplasia 0.3022075652254231 2.0758589623626396 0.0379069971537218 1.0 0.1897975790464133 129 P00374,Q8IY37,Q93008,O95352,P51532,P42356,Q00535,Q13535,Q9P2D1,Q9Y4A5,Q9UPN3,Q14204,P27635,P78527,Q9BUK6,O43505,Q9NZJ4,Q08AM6,O14802,Q69YN2,Q9BV10,O60826,Q15042,Q99986,Q7Z460,Q6W2J9,Q9UID3,Q9BPU6 28 +Displacement of the urethral meatus 0.3028083719611788 2.0698988241303566 0.0384618200889304 1.0 0.1919345838796687 124 P08708,Q07020,P62847,Q8IY37,Q93008,P61353,O43933,P51532,Q13535,Q9H3P2,Q9NVI1,Q14999,P62081,P42766,Q6PGP7,P27635,Q06124,P49917,Q96EK5,Q07864,Q7Z6Z7,P42345,P62854,P60866,P61313,Q08AM6,O14802,Q9BV10,O60826,P29372,P61254,P62899,Q6W2J9,Q7LBC6 34 +Abnormality of endocrine pancreas physiology 0.7120727380507326 2.0671242145251534 0.0387224509497223 1.0 0.1926932753301718 5 P40763,P53985 2 +Abnormal nasal bridge morphology 0.2504877822142236 2.0624059536693635 0.0391691029622474 1.0 0.1942726569827755 288 Q2VPK5,Q3SYG4,P08708,Q07020,P62847,O15357,P61353,Q93008,A5YKK6,O43933,P10589,P51532,P21359,O75909,Q12873,A1X283,Q4G0J3,Q9H3P2,Q9P2D1,Q9Y4A5,P57081,Q9NRZ9,Q9UET6,Q14999,O43709,P62081,P26196,P42766,P42858,P40763,Q6PGP7,P35573,Q9Y296,P27635,P26640,P78527,P18074,Q06124,Q9Y4X0,Q96EK5,P49917,Q07864,Q7Z6Z7,P42345,O00203,P62854,P60866,O00443,P61313,Q96N67,Q5SRE5,Q9BV10,Q15477,O60826,P28482,P62266,P29372,P22681,P31939,Q15042,P62899,P61254,Q6W2J9,Q9BPU6 64 +Depressed nasal bridge 0.2826718810273739 2.06233996214369 0.0391753809146331 1.0 0.1942726569827755 173 Q2VPK5,P08708,Q07020,P62847,O15357,P61353,Q93008,A5YKK6,O43933,P51532,P21359,A1X283,Q4G0J3,Q9P2D1,Q9Y4A5,P57081,Q9NRZ9,Q9UET6,Q14999,P62081,P26196,P42766,P42858,P35573,Q9Y296,P26640,Q9Y4X0,P49917,Q07864,Q7Z6Z7,P42345,P62854,P60866,O00443,P61313,O60826,P62266,P22681,Q15042,P62899,P61254,Q9BPU6 42 +Flat acetabular roof 0.7099856313919214 2.056799362991226 0.0397055293958859 1.0 0.1961045043931709 5 Q14839,O15357 2 +Abnormality of small intestinal villus morphology 0.7133390897698462 2.052497659899443 0.0401213222417695 1.0 0.1973886838358554 6 P50851,Q15477 2 +Facial erythema 0.699887505730731 2.0512813643232946 0.0402395542263813 1.0 0.1973886838358554 3 O00170 1 +Abnormal aldolase level 0.6941211578633132 2.0463245180550453 0.0407244530021952 1.0 0.1989670904662761 2 O43505 1 +Abnormal nasal mucosa morphology 0.7066978967113884 2.0405146642378793 0.0412990919862481 1.0 0.2002007725354511 5 Q86Y56,P57076,Q03518 3 +Widened cerebral subarachnoid space 0.6975862930250902 2.039907978802679 0.0413594919198536 1.0 0.2002007725354511 3 O43776 1 +Exercise induced muscle stiffness 0.6920322291853096 2.036005969105252 0.0417497558836319 1.0 0.2014556735263537 2 P53985 1 +Megaloblastic anemia 0.7163123099434396 2.0313493814354255 0.0422195653568133 1.0 0.2026627003027888 8 P00374 1 +Increased circulating iga level 0.7019855485632216 2.0171304494133455 0.0436819017719003 1.0 0.2047320296373338 5 P49327,Q9Y5L0,Q96BN8 3 +Bronchitis 0.7120925603431548 2.010273093909498 0.0444022929531291 1.0 0.2058570627063163 8 P57076,Q03518,P54132,Q13315,Q86Y56 5 +Anteverted ears 0.6960286652731968 2.0094229642839867 0.044492296855342 1.0 0.2060672343310169 4 P27635,Q6W2J9,Q6NXR4 3 +Abnormal leukocyte count 0.3000906905935559 2.008558809043338 0.0445839433732149 1.0 0.2062845845342431 118 P08708,Q07020,P62847,P61353,P49327,Q5F1R6,Q9P2D1,Q9NVI1,Q9NRZ9,P62081,P17812,P42766,Q96BN8,P40763,Q6PGP7,P18074,P49917,P26639,O00203,P62854,P60866,P61313,Q13315,Q9BV10,Q15477,O14617,P22681,P50851,P29144,P61254,P62899,Q6W2J9 32 +Joint hypermobility 0.3326033672408049 1.998313706664296 0.0456826604251912 1.0 0.2090235475670096 101 Q9Y263,Q93008,P21359,Q01968,Q13535,Q5F1R6,Q9Y6D5,Q14999,O43709,P26196,P42858,Q9Y296,Q8IWS0,Q06124,Q9Y4X0,P49917,Q7Z6Z7,O14802,O75182,P28482,P22681,Q9BPU6,Q15042,P46821,Q7LBC6 25 +Abnormality of the endometrium 0.7094712975185382 1.997161052317559 0.0458076904845849 1.0 0.2092186893122679 8 Q07864,P20585,P28340 3 +Abnormal pancreas size 0.7124047637379045 1.9949761348129835 0.0460454828021215 1.0 0.2095023963346871 9 P40763,A5YKK6,Q5F1R6 3 +Exercise induced muscle cramps 0.6951070517515099 1.982906830199835 0.0473778375955973 1.0 0.2128746081312403 5 P08237,P06737 2 +Adenocarcinoma of the colon 0.7343271698007321 1.9681204013858276 0.0490541859930746 1.0 0.2177996888046076 21 P08708,Q07864,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,P28340 13 +Total anomalous pulmonary venous return 0.6805970149253774 1.955560707670068 0.0505169253740522 1.0 0.2215157573673984 3 P60953,P62244 2 +Recurrent bronchitis 0.6885018612426745 1.949943734896869 0.0511828256157453 1.0 0.2231629249200694 5 Q03518,Q13315 2 +Autoimmune hemolytic anemia 0.7025255095516003 1.9452998585751184 0.0517388991471974 1.0 0.2247377982730901 9 P49327,P50851,P29144,P40763 4 +Abnormality of the thyroid gland 0.2960323181566455 1.933021179401136 0.0532335887862505 1.0 0.2297161319653635 114 Q9Y263,O00170,Q5TBB1,Q93008,P20585,P51532,P42771,P49327,Q9P2D1,Q9Y3Z3,Q9NVI1,P57081,P52701,O43709,Q9Y5L0,P40763,Q6PGP7,P27635,O14654,Q92908,P49917,Q9BUK6,P60866,O00443,O14802,Q9UDY8,Q15477,O96017,Q06787,P50851,Q9Y223,Q6W2J9,P54277 33 +Falls 0.6883806256988965 1.9280372535179384 0.0538504926080025 1.0 0.2304089570047874 6 Q9NZJ4 1 +Abnormality of upper limb metaphysis 0.6702476872575205 1.9277901469633272 0.0538812337742129 1.0 0.2304089570047874 2 P26373 1 +Abnormal sperm motility 0.6792966839682776 1.9260359152617883 0.0540998894735684 1.0 0.231076657538492 4 Q86Y56,Q9UBS4 2 +Severe demyelination of the white matter 0.6693524321098167 1.923319645141458 0.0544399188920716 1.0 0.2315667115993704 2 Q96C36 1 +Hypoplastic heart 0.6732476044435165 1.918869594635616 0.0550008394698271 1.0 0.2325681628177386 3 O60826 1 +Neutrophilia 0.6684571769620875 1.9188473445709704 0.0550036561097231 1.0 0.2325681628177386 2 Q96BN8 1 +Decreased fertility in females 0.6933244130246062 1.916066076391888 0.0553566856277716 1.0 0.2334190043884008 8 P57076,O00170,Q8IY37,P54132,Q96RD7,Q86Y56 6 +Non hodgkin lymphoma 0.7034657430155385 1.903555769433184 0.0569680639148635 1.0 0.2382535619576296 12 O96017,P52701,Q07864,P42771,Q13315,Q9UDY8 6 +Exercise induced muscle fatigue 0.6727260241074019 1.8931208510718145 0.0583417998755817 1.0 0.2426787401497372 4 Q92908,P53985 2 +Increased muscle fatiguability 0.6727260241074019 1.8931208510718145 0.0583417998755817 1.0 0.2426787401497372 4 Q92908,P53985 2 +Abnormality of the thenar eminence 0.7166797053270287 1.891128145791268 0.0586072401731407 1.0 0.2435632422690977 19 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Adenocarcinoma of the intestines 0.7189036119087647 1.8747797269301003 0.0608230333172863 1.0 0.2500683179078804 23 P08708,Q07864,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,P28340 13 +Persistence of hemoglobin f 0.716035578133411 1.8653878637491392 0.0621270572541885 1.0 0.2533495041891396 22 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q5F1R6 12 +Recurrent herpes 0.6751670775355129 1.861601905157916 0.0626592245609227 1.0 0.2544427842425499 6 Q14790,P29144,Q00653,P54132 4 +Rheumatoid factor positive 0.661449974487676 1.8597234122543005 0.0629246678803983 1.0 0.2552959480494963 3 P49327 1 +Abnormal erythrocyte enzyme level 0.7116824047030844 1.85666185852325 0.0633592771912452 1.0 0.2560071548571423 20 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Solitary median maxillary central incisor 0.6653570545866889 1.8560971429084097 0.063439712924618 1.0 0.2560071548571423 4 A5YKK6 1 +Abnormal cd4 cd8 ratio 0.6740175117968024 1.8558051027591091 0.0634813429912295 1.0 0.2560071548571423 6 O00203,P17812,O95394,Q14790 4 +Generalized hypopigmentation 0.6848178265210529 1.855755314753228 0.0634884424792046 1.0 0.2560071548571423 9 Q01968,Q6PGP7,O14617,Q15477 4 +Decreased circulating level of specific antibody 0.6762064450960343 1.8477916690737408 0.0646324865645509 1.0 0.2588104692033622 7 P49327,P50851,P17812 3 +Abnormal muscle glycogen content 0.6720968958168603 1.846114268826911 0.064875615450354 1.0 0.2595165005505079 6 P08237,Q9BUK6,P13807,P46976 4 +Neutropenia in presence of anti neutropil antibodies 0.6757693858550049 1.845581593570473 0.0649529811361842 1.0 0.2595165005505079 7 P49327,P29144,P40763 3 +Abnormal lip morphology 0.2382762850655471 1.8453361319343524 0.0649886575614164 1.0 0.2595165005505079 313 O15357,O60701,P51532,O75909,Q9H3P2,P42695,Q9NR45,Q9UET6,P42858,P46777,Q00534,Q92908,Q9Y4X0,Q96EK5,Q08AM6,O14802,Q05639,O60826,O14617,Q06787,P60953,Q92974,Q9Y223,Q9BPU6,Q01433,P36507,P68400,Q9Y263,Q15436,Q9BSJ2,A1X283,Q9Y4A5,P33992,P17612,P35573,P27635,P78527,Q7Z6Z7,P62266,Q15042,Q9UID3,Q96C86,Q7LBC6,Q9UPP1,Q8IY37,Q93008,A5YKK6,P21359,Q01968,Q9P2D1,Q14999,P62081,Q9Y296,P67870,P18074,Q96N67,O15111,P28482,P29372,P46821,Q6W2J9,O00170,O95352,Q4G0J3,P57081,O43709,P26196,Q6PGP7,Q96F07,Q06124,P49917,P42345,O00203,Q00610,Q9BV10,Q13555,P22681,P31939,P63241 79 +Colorectal polyposis 0.6822302599411474 1.842618402316001 0.0653847451685016 1.0 0.260368357740751 9 O96017,Q07864,P28340,P42771 4 +Large intestinal polyposis 0.6822302599411474 1.842618402316001 0.0653847451685016 1.0 0.260368357740751 9 O96017,Q07864,P28340,P42771 4 +Abnormality of the foot musculature 0.6626366060195183 1.842400199163603 0.0654166326948906 1.0 0.260368357740751 4 P50570,Q8NCE2 2 +Abnormal proximal phalanx morphology of the hand 0.6661678240649184 1.8377913399985364 0.0660931582174164 1.0 0.2622182233803766 5 Q08AM6 1 +Abnormality of neuronal migration 0.2819707299250948 1.8342016479864225 0.0666240669056916 1.0 0.2632088933082417 155 Q2VPK5,Q9Y263,Q8IY37,Q93008,O43933,P51532,P42356,Q00535,O43776,Q13535,Q9Y4A5,Q9Y6D5,P42695,P57081,Q9ULK4,Q9UPN3,P08243,Q14204,Q00534,P67870,Q96F86,P78527,Q96EK5,O43505,O60524,P42345,Q9UBB6,Q00610,Q08AM6,O14802,Q9BV10,P47897,Q05639,O60826,O60231,Q15042,P46821,Q96C86,Q2M389 39 +Split nail 0.6607046385463831 1.8326638753161872 0.0668525726535449 1.0 0.2632088933082417 4 P18074 1 +Abnormal c reactive protein level 0.6692560501941841 1.8317667543792289 0.0669861783533223 1.0 0.2632088933082417 6 P22314,P53621,P14174,Q8N8R5,Q96BN8 5 +Aplasia hypoplasia of the cerebellum 0.2851462298241108 1.8284041751552969 0.0674889152347075 1.0 0.2647333044028112 144 P00374,Q8IY37,Q93008,O95352,P51532,P42356,Q00535,Q13535,Q9H3P2,Q9P2D1,Q9Y4A5,Q9UPN3,Q14204,P27635,P78527,P18074,Q9BUK6,O43505,Q9NZJ4,Q08AM6,O14802,Q69YN2,Q92917,Q9BV10,O60826,Q15042,Q99986,Q7Z460,Q6W2J9,Q9UID3,Q9BPU6 31 +Decreased serum insulin like growth factor 1 0.6543283582089601 1.8238766386668184 0.0681707241922258 1.0 0.2663650596660589 3 Q9BV10,Q00653 2 +Adrenocorticotropin deficient adrenal insufficiency 0.6543283582089603 1.8238766386668168 0.068170724192226 1.0 0.2663650596660589 3 O00170,Q00653 2 +Abnormal left ventricular outflow tract morphology 0.6633811230585365 1.8237252951744756 0.068193612717454 1.0 0.2663650596660589 5 Q06124,Q15645,O43683,O43684 4 +Subvalvular aortic stenosis 0.6633811230585365 1.8237252951744756 0.068193612717454 1.0 0.2663650596660589 5 Q06124,Q15645,O43683,O43684 4 +Proximal femoral metaphyseal abnormality 0.6584834983831798 1.821460859688793 0.068536831177312 1.0 0.2667066627719771 4 Q5F1R6 1 +Decreased specific antibody response to vaccination 0.6629178524956424 1.8213854080014331 0.0685482917201767 1.0 0.2667066627719771 5 Q9BV10,P50851,P17812 3 +Ulnar deviation of the hand 0.6658372998715825 1.8144795064054964 0.0696039350451482 1.0 0.2695910599187817 6 Q9BPU6 1 +Pancreatic hypoplasia 0.6677964302771173 1.8051995820900495 0.0710434563274575 1.0 0.2726484725778383 7 P40763,Q5F1R6 2 +Abnormality of prenatal development or birth 0.2469998793772856 1.8040391759936911 0.0712251656948539 1.0 0.2728992682750168 253 Q9NPL8,P08708,Q07020,P62847,O15357,P61353,Q93008,A5YKK6,O43772,O43933,P42771,P49327,Q7KZN9,P38935,Q9H3P2,Q86Y56,Q9P2D1,Q9NVI1,Q8IUX1,P57081,O43709,P62081,P26196,P42766,P41252,Q6PGP7,P46777,Q96F07,P27635,O00217,P18074,Q06210,Q92908,Q9Y4X0,Q06124,O94903,P26639,P50570,P62854,P60866,P61313,Q00610,Q08AM6,Q9H4L7,Q5SRE5,O14802,Q92917,Q9BV10,Q13501,O15111,O96017,Q05639,O60826,P57076,P28482,P22681,Q8NC96,P61254,P62899,Q7LBC6,P63241,Q9BTW9,Q9BPU6,Q8NCE2 64 +Short upper lip 0.6634220525022421 1.8022529014044752 0.0715056249967651 1.0 0.2732853754018871 6 Q08AM6 1 +Abnormal serum insulin like growth factor 1 level 0.6545237384293667 1.801463996338973 0.0716297771383496 1.0 0.2735332466384162 4 Q9BV10,Q00653,O00170 3 +Osteopetrosis 0.6498060516129872 1.8010593016198682 0.0716935335594119 1.0 0.2735502649376075 3 P48651 1 +Impaired horizontal smooth pursuit 0.652947697752785 1.793496310882414 0.0728935999950382 1.0 0.2746098364592969 4 Q9NW08 1 +Large beaked nose 0.668635717774723 1.7910444441956446 0.0732861632073702 1.0 0.2750431407961277 8 P49917,Q5TBB1,P18074,O14802 4 +Broad femoral neck 0.6477611940298557 1.7907284138422288 0.0733368877475042 1.0 0.2750431407961277 3 Q8WVQ1,Q9NUQ7 2 +Perisylvian polymicrogyria 0.6562523882912257 1.7876728918196108 0.073828797734972 1.0 0.2762143097740683 5 P42356,Q15042 2 +Aplasia hypoplasia of the pubic bone 0.6600365692970239 1.7850959698675346 0.074245751570745 1.0 0.2770126395356196 6 Q14999,O15357 2 +Neoplasm of the larynx 0.6556259595690631 1.7845001285564044 0.0743424339356377 1.0 0.2770126395356196 5 O96017,P42771 2 +Erythroid hypoplasia 0.6976998961076409 1.7830546891168304 0.0745774012883591 1.0 0.2776638838928172 20 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Abnormality of skin pigmentation 0.2856586848530369 1.779275125568062 0.0751946669774121 1.0 0.2795108773302194 135 O00170,Q93008,P42771,P21359,Q01968,P53618,A1X283,P49327,Q5F1R6,P52701,P26196,P42858,Q9Y5L0,Q6PGP7,Q9Y296,Q96IJ6,P18074,Q06124,P49917,Q7Z6Z7,P26639,P42345,O00203,Q9H4L7,Q13315,Q15477,O60333,O14617,P28482,P22681,P50851,Q96C86,Q9BPU6 33 +Abnormal thrombocyte morphology 0.2874610207130486 1.7772491420582 0.0755272572947789 1.0 0.2805211255240058 125 P00374,P08708,Q07020,P62847,P61353,Q01968,P49327,Q5F1R6,Q9NVI1,P62081,P42766,P40763,Q6PGP7,Q06124,P49917,P42345,O00203,P62854,P60866,P61313,P50747,Q9BV10,Q15477,P22681,P35579,P50851,P29144,Q9HC07,P61254,P62899,Q6W2J9 31 +Increased muscle glycogen content 0.6492920272766416 1.774996377852159 0.0758984852657591 1.0 0.2812206526352988 4 P08237,Q9BUK6 2 +Abnormal blood chloride concentration 0.6445408575046188 1.774442032813792 0.0759900624217477 1.0 0.2813339951456842 3 Q9UNF1 1 +Abnormality of dna repair 0.6490835689565511 1.773940672620221 0.0760729641561739 1.0 0.2814150630733202 4 P18074 1 +Impaired tactile sensation 0.6680422530944088 1.7703638714834424 0.0766665442125016 1.0 0.282478249562516 9 Q5TAQ9,Q9NZJ4 2 +Neoplasm of the gastrointestinal tract 0.3797112080264807 1.766055712702965 0.0773865024826538 1.0 0.2849033806484297 95 P08708,Q07020,P62847,P61353,P20585,P51532,P42771,P21359,P49327,P28340,Q9UER7,P52701,O14965,P06737,P62081,P42766,Q9Y5L0,Q6PGP7,P46777,Q07864,P42345,P62854,P60866,P61313,Q15477,O96017,P61254,P62899,P54277 29 +Milia 0.6420660926528969 1.7619124806855226 0.0780840855878479 1.0 0.2869754034447028 3 Q9H4L7 1 +Reticulocytopenia 0.6949896177444181 1.760790567724389 0.0782738568891936 1.0 0.2872532234127686 21 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Abnormal anterior eye segment morphology 0.2342323402079551 1.757056017217491 0.0789082615606164 1.0 0.2891213745664208 318 O75569,P08708,Q3SYG4,Q07020,P62847,P61353,Q93008,O43933,P10589,P21359,Q01968,P49327,P53618,A1X283,P26358,Q13126,Q5F1R6,Q9P2D1,P52701,O43709,P62081,P26196,P42766,P42858,Q14839,Q9Y296,Q96IJ6,P26640,P18074,Q8IWS0,Q9Y4X0,Q96EK5,P49917,O43505,Q7Z6Z7,P57678,P26639,O00203,P62854,Q8NHU6,O00443,P60866,P61313,Q96C23,Q08AM6,P50747,Q5SRE5,O14802,O15111,O60333,O60826,O14617,P28482,P35579,P40818,Q15042,P62899,Q6W2J9,Q9BPU6 59 +Abnormal proportion of cd4 positive t cells 0.6579945726523048 1.755390405410207 0.079192552085737 1.0 0.2899327323583374 7 O95394,P54132,P49327,Q96BN8,Q13315 5 +Malignant genitourinary tract tumor 0.6945706212181575 1.7513856780700452 0.0798794982999893 1.0 0.2917530686127084 22 P52701,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 12 +Recurrent bronchopulmonary infections 0.6441386045327565 1.7488734405910098 0.0803128984839605 1.0 0.2924099453090054 4 P18074 1 +Broad neck 0.6757446127004211 1.7471068032689447 0.0806188135134706 1.0 0.2929685614629685 13 Q8IY37,O60826,P62854,Q07864 4 +Abnormal circulating amylase level 0.6521774454128502 1.7451853829007946 0.0809526047776141 1.0 0.2938114601409393 6 A5YKK6 1 +Increased mean corpuscular volume 0.6955580316804282 1.7447142563530402 0.0810346204590966 1.0 0.2938779120894753 24 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q5F1R6 12 +Lop ear 0.637413865270795 1.738326778703302 0.0821532504377797 1.0 0.2970007400231019 3 Q9P2D1 1 +Deep plantar creases 0.6462907779902203 1.7371317207968002 0.0823639234476856 1.0 0.2975291925326341 5 O00170 1 +Bifid epiglottis 0.6317517159056956 1.7340039014691733 0.082917390926207 1.0 0.2992941505028116 2 Q8NCM8 1 +Heterotaxy 0.6478638914176852 1.7232328278909306 0.0848464294430475 1.0 0.3042729426879907 6 Q7LBC6,Q9H3P2 2 +Abnormality of the urethra 0.2825124052377306 1.72197637668617 0.0850737979297542 1.0 0.3046936567158045 136 P08708,Q07020,P62847,Q8IY37,Q93008,P61353,O43933,P51532,Q13535,Q9H3P2,Q9NVI1,Q14999,O43709,P62081,P42766,Q6PGP7,P27635,Q06124,P49917,Q96EK5,Q07864,Q7Z6Z7,P42345,P62854,P60866,P61313,Q08AM6,O14802,Q9BV10,O60826,P29372,P61254,P62899,Q6W2J9,Q7LBC6 35 +Ridged nail 0.6506685294693295 1.7180500842530413 0.085787480302423 1.0 0.3067733694845561 7 Q13535,P18074 2 +Absence of secondary sex characteristics 0.6461697189346434 1.714601965650297 0.0864182281203724 1.0 0.3078290818756041 6 Q8IY37,Q9P2D1,Q9BZH6 3 +Anophthalmia 0.6535804724732851 1.714248542935655 0.0864830891200483 1.0 0.3078290818756041 8 O75569,Q6W2J9,Q9P2D1,Q96N67 4 +Increased blood urea nitrogen 0.6272754401671018 1.7112764170041386 0.0870300976958713 1.0 0.3092700215667432 2 O95163 1 +Horizontal ribs 0.63194029850747 1.7105252378955855 0.0871687905753906 1.0 0.3093151007109823 3 Q8NCM8,Q14999 2 +Male infertility 0.6488354538456214 1.7086926559187858 0.0875078952072971 1.0 0.3095143535503023 7 Q06124,Q8IY37,P57076,Q86Y56 4 +Abnormal cerebral cortex morphology 0.2478749111866766 1.705861236411981 0.0880339184812983 1.0 0.3100220549566265 234 P36507,Q2VPK5,P68400,Q9Y263,Q8IY37,Q93008,O43933,P51532,P42356,Q00535,O43776,Q13535,O75165,Q9Y4A5,P42695,P57081,Q9ULK4,Q9UPN3,O43709,P26196,P42858,P08243,Q14204,Q00534,Q9Y296,P67870,P26640,Q96F86,P78527,P18074,Q96EK5,O43505,O60524,Q7Z6Z7,Q9NZJ4,P26639,P42345,Q9UBB6,Q00610,Q96N67,Q08AM6,O14802,Q92917,Q9BV10,Q13501,P47897,Q05639,O75182,Q06787,Q04637,P60953,Q9NW08,Q15042,P46821,Q96C86,Q9BTW9,Q9BPU6,Q2M389,Q01433 59 +Reduced sperm motility 0.6307544687564481 1.704494922047122 0.0882886639293833 1.0 0.3100220549566265 3 Q9UBS4 1 +Abdominal wall muscle weakness 0.6397849462365481 1.7040266342987382 0.0883761114823247 1.0 0.3100220549566265 5 P36507,P46976,A6NHR9,P21359 4 +Abnormal st segment 0.6351902867634669 1.7033974768906812 0.0884937095696654 1.0 0.3101986947149441 4 Q92908,Q99996 2 +Auditory hallucinations 0.62339600119367 1.691549279619719 0.090731944200622 1.0 0.3163616467101053 2 P18583 1 +Attention deficit hyperactivity disorder 0.2823346317651801 1.688194731548476 0.0913738542328008 1.0 0.318118935528989 109 P68400,Q93008,P46109,Q08209,P10589,P21359,Q01968,Q6DN90,Q9P2D1,P52701,Q9UET6,Q15058,O43709,P26196,P42858,Q13045,Q9Y296,Q08J23,Q96F07,P49917,Q7Z6Z7,P60866,Q9UIG0,Q00610,Q05639,Q12830,P49589,Q06787,P28482,Q8NC96,Q9BPU6,Q9Y223,P46821,Q7LBC6,P54277 35 +Absent testis 0.631682047823822 1.685529588295516 0.0918864411590734 1.0 0.3185113784384954 4 Q8IY37,Q9NVI1 2 +Recurrent tonsillitis 0.6207102357505156 1.6778761358273893 0.0933712821653596 1.0 0.3207161017340418 2 P54132 1 +Cutaneous abscess 0.6207102357505125 1.6778761358273733 0.0933712821653627 1.0 0.3207161017340418 2 O95394 1 +Postaxial foot polydactyly 0.6494643370064838 1.6752238573520797 0.0938903183414328 1.0 0.3217362474932468 9 Q3SYG4 1 +Abnormality of the 5th toe 0.6494643370064838 1.6752238573520797 0.0938903183414328 1.0 0.3217362474932468 9 Q3SYG4 1 +Increased head circumference 0.2820528766375496 1.6713373526803563 0.0946550624500166 1.0 0.3234282617835703 124 O15357,Q93008,O43933,P21359,O75909,Q12873,Q13144,Q9NRZ9,P26196,Q14839,P42858,Q9Y296,Q8IWS0,O43505,Q07864,Q7Z6Z7,P42345,P50570,Q99575,O14802,Q9HCK8,Q16512,O60826,Q13555,O14646,Q9BPU6,Q8NCE2 27 +Choroid plexus carcinoma 0.6241766436161493 1.6709994710854237 0.0947217822825934 1.0 0.3234282617835703 3 P42771 1 +Right ventricular dilatation 0.6235820895522444 1.6679682064428554 0.0953220383678092 1.0 0.3241044106751062 3 Q92908,Q7Z392 2 +Shoulder dislocation 0.6326958337409032 1.6678708965853175 0.0953413581803857 1.0 0.3241044106751062 5 Q9Y6D5 1 +Amelogenesis imperfecta 0.6324439809439173 1.6665848757306916 0.0955969783113714 1.0 0.324734065500999 5 Q9HC07,O43933 2 +Corneal scarring 0.6217910447761245 1.6588331650467818 0.0971494153428309 1.0 0.3276645698718601 3 Q86XI2,P09884 2 +Chronic mucocutaneous candidiasis 0.6342193159617499 1.6535856582217 0.0982117286685764 1.0 0.3301454070664036 6 O00203,P40763 2 +Generalized onset seizure 0.2802031162813261 1.648832926374262 0.0991818673834528 1.0 0.3320217374745049 109 P00374,Q9Y263,Q93008,O43776,Q14746,Q9UET6,Q9ULK4,P40763,Q14204,P67870,P27635,Q96F86,P18074,Q14353,O60524,O94903,P26639,P42345,Q9UBB6,Q00610,Q96N67,P28482,Q9C0E8,Q96C86,Q9BTW9,Q2M389 26 +Decreased proportion of cd4 positive helper t cells 0.6287293028787044 1.6476050622043272 0.0994337409698611 1.0 0.3320409956280842 5 P49327,O95394,Q13315 3 +Chorioretinal coloboma 0.6368550254451311 1.6474015459511206 0.0994755378187757 1.0 0.3320409956280842 7 Q9P2D1,O60826 2 +Abnormality of the cerebral subcortex 0.23417026546542 1.6445199477111858 0.1000688473347988 1.0 0.3335387230891813 391 P10589,P51532,Q00535,Q13535,P26358,Q9H3P2,Q9Y6D5,Q9H1B7,P42695,Q9NVI1,Q9NR45,Q9ULK4,Q9UPN3,Q8N8R5,P42858,Q00534,Q9Y3I1,Q9H269,Q96EK5,Q9NZJ4,O00443,Q08AM6,O14802,Q9NW08,Q9BTW9,Q9BPU6,Q01433,Q9Y263,O43776,A1X283,Q9Y4A5,Q14746,Q14204,P27635,P26640,O00217,P78527,Q9BUK6,Q7Z6Z7,O60231,Q9C0E8,Q9HC07,Q15042,Q9UID3,Q96C86,Q7LBC6,Q93008,A5YKK6,O43933,P21359,Q01968,Q9Y296,P67870,P18074,Q96N67,Q13501,O75182,P29372,Q99986,P46821,Q6W2J9,Q2M389,O95352,Q7KZN9,P57081,P07814,P26196,Q96F07,Q96F86,P49917,O43505,O60524,O94903,P26639,P42345,Q00610,Q5SRE5,Q69YN2,Q92917,Q9BV10,Q16512 81 +Abnormal circulating ige level 0.6271763989375716 1.639664214878782 0.101075003352145 1.0 0.3357934653471667 5 P49327,P40763 2 +Hodgkin lymphoma 0.6422439904688828 1.6381018236952398 0.1014004546344251 1.0 0.3357934653471667 9 O96017,Q07864,P42771,P49327,P40763,Q13315 6 +Lumbar scoliosis 0.6209458714862923 1.6307212251498022 0.1029491558653945 1.0 0.3406775150696306 4 P27635 1 +Aplasia hypoplasia of the spleen 0.624850657108712 1.627764515997773 0.1035748272197558 1.0 0.3422569326394941 5 Q86Y56,Q8TD19,P57076,Q7L590 4 +Abnormal proportion of cd8 positive t cells 0.6191643699437105 1.6216088812428997 0.1048871198202352 1.0 0.3460974847859407 4 P49327,O95394 2 +Intellectual disability mild 0.2780892378305486 1.6195696523683534 0.105324753037479 1.0 0.3470450612584933 133 P00492,Q9UPP1,Q08209,P21359,P54132,Q6DN90,Q5F1R6,Q9ULK4,P26196,P42858,Q14204,P54136,Q6PGP7,Q00534,P35573,Q9Y296,Q08J23,P67870,Q96F86,Q9H269,Q06124,Q9BUK6,O60524,Q7Z6Z7,O00203,Q9NUQ7,Q9UBB6,Q00610,O14802,Q15477,P43034,Q05639,Q12830,P49589,Q06787,O75182,Q9NW08,Q6W2J9,Q9Y223,Q2M389,Q96C86,Q9BPU6,Q13618 43 +Triphalangeal thumb 0.6716898451103431 1.6160411933686265 0.1060854072004628 1.0 0.3475653291304938 24 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q9NVI1 12 +Abnormality of the periungual region 0.6221674308442464 1.614025682291037 0.1065218557490466 1.0 0.3487454423701647 5 P40763,P54132 2 +Abnormal mean corpuscular volume 0.6732140867622092 1.6106891216913413 0.1072474979000437 1.0 0.3490244129999482 27 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q5F1R6 12 +Abnormal natural killer cell morphology 0.6212664277180308 1.609409940885913 0.1075267330241316 1.0 0.3490244129999482 5 O00203,P33991,O95394,Q7L590 4 +Reduced natural killer cell count 0.6212664277180308 1.609409940885913 0.1075267330241316 1.0 0.3490244129999482 5 O00203,P33991,O95394,Q7L590 4 +Chronic lymphatic leukemia 0.6165892382636686 1.6084286464183084 0.1077413319124054 1.0 0.3490244129999482 4 Q5TBB1 1 +Chronic leukemia 0.6165892382636686 1.6084286464183084 0.1077413319124054 1.0 0.3490244129999482 4 Q5TBB1 1 +Moyamoya phenomenon 0.6165892382636686 1.6084286464183084 0.1077413319124054 1.0 0.3490244129999482 4 Q5TBB1 1 +Neonatal alloimmune thrombocytopenia 0.6165892382636686 1.6084286464183084 0.1077413319124054 1.0 0.3490244129999482 4 Q5TBB1 1 +Chilblains 0.6165892382636686 1.6084286464183084 0.1077413319124054 1.0 0.3490244129999482 4 Q5TBB1 1 +Iris hypopigmentation 0.6205001776642335 1.6054836046204015 0.1083874184883737 1.0 0.3506249379290799 5 O14617 1 +Increased circulating acth level 0.6140935305720757 1.5956455877862057 0.1105679432887001 1.0 0.3561319000815713 4 O00170,Q9UER7 2 +Abnormal palate morphology 0.2320469243762571 1.5944637410505864 0.1108322056943384 1.0 0.3561319000815713 306 Q2VPK5,P08708,Q9UPP1,Q07020,P62847,O15357,Q9Y263,Q93008,A5YKK6,P61353,O43933,O95352,P21359,Q01968,P53618,Q12873,Q13535,A1X283,Q9H3P2,Q9P2D1,Q9Y4A5,Q9NVI1,P57081,P62081,P26196,P42766,P42858,P40763,Q6PGP7,Q9Y296,P18074,Q06210,Q06124,Q9Y4X0,Q96EK5,Q9BUK6,P49917,O43505,Q7Z6Z7,P57678,P26639,P62854,P60866,P61313,Q00610,Q08AM6,Q5SRE5,O14802,O15111,P46821,O60826,P28482,P62266,P29372,P22681,Q15042,P62899,P61254,P63241,Q6W2J9,Q9UID3,Q9BPU6 62 +Abnormal cortical gyration 0.2757428005234794 1.5921002386284129 0.1113621835007347 1.0 0.3562508685775933 137 Q2VPK5,Q9Y263,Q8IY37,Q93008,O43933,P51532,P42356,Q00535,O43776,Q13535,Q9Y4A5,P42695,P57081,Q9ULK4,Q9UPN3,P08243,Q14204,Q00534,P67870,Q96F86,P78527,Q96EK5,O43505,O60524,P42345,Q9UBB6,Q00610,Q08AM6,O14802,Q9BV10,P47897,Q15042,P46821,Q96C86,Q2M389 35 +Ambiguous genitalia male 0.6086567164179155 1.591684922104932 0.1114555178875149 1.0 0.3563023589848277 3 Q15392,Q9H0U9 2 +Hyperplasia of the maxilla 0.6028051327961739 1.586410730727934 0.1126461677866963 1.0 0.35886517403317 2 Q9H7D7 1 +Paronychia 0.6116723927579109 1.5832359461033445 0.1133676962657659 1.0 0.3604170798580139 4 P40763 1 +Cryptorchidism 0.2536310496294545 1.582771206379202 0.1134736217656324 1.0 0.3605053837499054 195 Q3SYG4,Q9UPP1,O15357,Q8IY37,O43933,P51532,P21359,Q01968,Q13535,P28340,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,O43709,P26196,Q14839,P42858,Q9Y296,P27635,P18074,Q8IWS0,Q06124,P49917,O43505,Q07864,Q7Z6Z7,P26639,P42345,P50570,O00443,Q08AM6,O14802,Q9BV10,O60826,P28482,P29372,P22681,Q15042,Q7LBC6,P63241,Q6W2J9,Q9BPU6,Q8NCE2 44 +Hypoplasia of the corpus callosum 0.2524175139238778 1.5702010123365564 0.1163683541295865 1.0 0.366524636971648 198 P36507,Q9Y263,Q5TBB1,Q93008,Q08209,P10589,P21359,Q9BSJ2,A1X283,O43776,Q6DN90,Q9Y3Z3,Q9Y4A5,Q9Y6D5,Q9NR45,Q14746,Q9ULK4,Q9UPN3,P07814,Q13885,P26196,O60610,P08243,Q14204,P54136,Q08J23,P67870,P26640,Q96F86,P78527,Q96EK5,Q96KP1,O60524,Q9NZB8,Q7Z6Z7,Q9NZJ4,O94903,Q9H7D7,Q9NUQ7,Q9UBB6,Q00610,Q96N67,O43924,Q5SRE5,O14802,Q9BV10,P43034,P47897,Q05639,P49589,P46821,Q6PJG6,Q6NXR4,P60953,Q9NW08,Q9C0E8,Q15042,Q5VIR6,Q9UID3,Q96C86,Q9BTW9,Q6W2J9,Q2M389,Q01433 64 +Irregular vertebral endplates 0.6176627201139382 1.568693627755282 0.1167193441191685 1.0 0.366524636971648 6 O14802 1 +Abnormal scrotal rugation 0.5992241122053088 1.5680575256879568 0.11686770782498 1.0 0.366524636971648 2 Q96GM8 1 +Nodular goiter 0.5992241122053055 1.5680575256879397 0.116867707824984 1.0 0.366524636971648 2 Q9UPY3 1 +Abnormal t cell proliferation 0.6039723313296592 1.5676734872153868 0.1169573521834523 1.0 0.366524636971648 3 P17812 1 +Reduced antigen specific t cell proliferation 0.6039723313296592 1.5676734872153868 0.1169573521834523 1.0 0.366524636971648 3 P17812 1 +High palate 0.2440032943998711 1.5661269553521708 0.1173188987456246 1.0 0.3670516333054044 226 P36507,Q2VPK5,P08708,P68400,Q07020,P62847,Q9Y263,P61353,Q93008,A5YKK6,O95352,O43933,P21359,P53618,Q12873,Q13535,A1X283,Q9NVI1,P57081,P62081,P26196,P42766,P42858,P40763,P46777,Q9Y296,P18074,Q06210,Q06124,P49917,Q9BUK6,Q7Z6Z7,P57678,P26639,P62854,P60866,Q9UBB6,P61313,Q00610,Q08AM6,Q5SRE5,P46821,O60826,P28482,P62266,P29372,P22681,Q92974,P62899,Q15042,P61254,Q6W2J9,Q9Y223,Q9UID3,Q9BPU6 55 +Acute kidney injury 0.6078730721353203 1.5637460386340456 0.1178772212375691 1.0 0.367410555114126 4 P00492,P07741 2 +Bruxism 0.6204692054138226 1.5632326799887797 0.1179978760754041 1.0 0.3675382865198104 7 P42858 1 +Atypical absence seizure 0.6029850746268719 1.5626090442732468 0.1181445796818672 1.0 0.367746927174395 3 Q05086,P43034 2 +Abnormal prostate morphology 0.6225255074514757 1.5547178096673815 0.1200132911087967 1.0 0.3725580833680212 8 Q8IWS0,P42771 2 +Partial duplication of the phalanx of hand 0.6567864644276818 1.549213553980272 0.121330392282398 1.0 0.3751321042886744 22 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Mood swings 0.5998471525843329 1.546503381125538 0.1219830441455873 1.0 0.3763666468012231 3 Q12830 1 +Pure red cell aplasia 0.6547168199633614 1.5462009752479684 0.1220560380695057 1.0 0.3763666468012231 21 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Lower limb asymmetry 0.608124126260412 1.5419570902869737 0.1230840212140051 1.0 0.3784536954115158 5 Q93008,P28482,Q15555 3 +Autoimmune thrombocytopenia 0.6200286206551981 1.5418363510804716 0.1231133661150229 1.0 0.3784536954115158 8 P49327,P50851,P29144,P40763 4 +Bimanual synkinesia 0.6019474653978412 1.5333109473559283 0.1251992585601413 1.0 0.3824528575208339 4 Q9P2D1,Q9BZH6 2 +Lower limb metaphyseal irregularity 0.6064325109086194 1.5332589160994747 0.1252120729907888 1.0 0.3824528575208339 5 P26373 1 +Choriocarcinoma 0.6013241463949278 1.5301069234594895 0.1259902648015143 1.0 0.3836258029896934 4 P42771 1 +Ulcerative colitis 0.5917636526409998 1.52976413748895 0.1260751214674513 1.0 0.3836309599797844 2 Q13043 1 +Lipoma 0.6051868599142254 1.526851723587661 0.1267978864349705 1.0 0.3848149013977101 5 P27635 1 +Hypoplasia of the frontal lobes 0.625943841241814 1.5196763031775735 0.1285923501409569 1.0 0.3897480362682223 11 P42695,Q00534 2 +Autoimmune antibody positivity 0.625227461134191 1.5159549267479693 0.1295307500176501 1.0 0.3918127727127883 11 O95394,P53621,Q00653,Q9Y5L0,P49327 5 +Neoplasm of the rectum 0.6365776969548664 1.5156606880494483 0.1296051728912322 1.0 0.3918127727127883 15 O96017,P52701,Q07864,P20585,P42771,P28340,P54277 7 +Glioblastoma multiforme 0.6185153161906906 1.5156284461476202 0.129613329971757 1.0 0.3918127727127883 9 O96017,P52701,P54277,P42771 4 +Abnormality of the vertebral endplates 0.6107004034137721 1.512894569863591 0.1303064414559203 1.0 0.3931351304356837 7 O14802 1 +Short middle phalanx of finger 0.5962467302769463 1.5039908274342393 0.1325837285390885 1.0 0.3971485323057241 4 Q08AM6 1 +Absent thumb 0.6528128524540087 1.5029999882152263 0.1328390470321598 1.0 0.3976551096426693 26 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q08AM6,Q9NVI1 13 +Abnormal myeloid leukocyte morphology 0.2811561558182151 1.4949257382111223 0.1349338242081001 1.0 0.4018397230935869 103 P08708,Q07020,P62847,P61353,P49327,Q5F1R6,Q9P2D1,Q9NVI1,Q9NRZ9,P62081,P42766,Q96BN8,P40763,P18074,P49917,P26639,O00203,P62854,P60866,P61313,O14617,P22681,P35579,P50851,P29144,P61254,P62899,Q6W2J9 28 +Desquamation of skin soon after birth 0.602881127020566 1.4926092203839936 0.1355395083802331 1.0 0.4031229865622278 6 P49917,Q9P2D1 2 +Unexplained fevers 0.6063154275113901 1.4902666735153642 0.136154131566256 1.0 0.4039638749641853 7 Q5TBB1,Q9HC07 2 +Patellar hypoplasia 0.5840047746941135 1.4898636585837564 0.1362600887587843 1.0 0.4039638749641853 2 Q9H1A4 1 +Abnormality of blood volume homeostasis 0.5883447912264883 1.487361788153683 0.1369192834647368 1.0 0.4056574531938541 3 P40763 1 +Secundum atrial septal defect 0.5963764232647419 1.4814857800541028 0.1384771714215378 1.0 0.4094840972868935 5 A1X283,P21359 2 +Happy demeanor 0.5900268736936416 1.471960582983805 0.1410315220751712 1.0 0.415174480748414 4 Q9H7D7,Q9NUY8,Q05086 3 +Anisocoria 0.5932839691134896 1.4655441395338185 0.1427725189532651 1.0 0.4190526442368412 5 P26196 1 +Abnormal platelet volume 0.6051868673848254 1.4651391104236906 0.1428829680285557 1.0 0.4190526442368412 8 P35579,Q6PGP7,Q15477 3 +Abnormality of urinary uric acid concentration 0.5840222992798282 1.46509883711015 0.142893953909506 1.0 0.4190526442368412 3 Q9NZB8 1 +Decreased fertility in males 0.6146889834249981 1.4611632101158707 0.1439706566944929 1.0 0.4208723950137489 11 Q06124,P57076,O00170,Q8IY37,Q86Y56,Q9NVI1 6 +Thoracolumbar scoliosis 0.6034897709185421 1.4563570483906556 0.1452939425965116 1.0 0.423399214906954 8 P27635,Q93008,Q99575 3 +Large basal ganglia 0.6309979282031125 1.449459947828213 0.1472091777532351 1.0 0.428439076956261 18 O60524,Q9ULK4,Q96F86,Q9UBB6,Q13535,Q6DN90,Q08J23,Q96C86,Q2M389 9 +Clubbing of toes 0.5807665401756248 1.4483181128732248 0.1475281043119873 1.0 0.4286040353988199 3 Q9NVI1 1 +Duodenal stenosis 0.5807665401756248 1.4483181128732248 0.1475281043119873 1.0 0.4286040353988199 3 Q9NVI1 1 +Chylothorax 0.585428999943354 1.4482591301161232 0.1475445931526828 1.0 0.4286040353988199 4 Q06124 1 +Downslanted palpebral fissures 0.2656331630657691 1.4450854132555888 0.1484338956694075 1.0 0.4303743310640963 148 Q3SYG4,Q93008,P21359,A1X283,Q13535,Q9H3P2,Q5F1R6,Q9P2D1,Q9UET6,P26196,P42858,Q14204,Q6PGP7,Q9Y296,Q96F07,Q06124,Q9Y4X0,Q96EK5,Q7Z6Z7,P42345,Q00610,O14802,Q9HCK8,Q05639,O60826,O14646,P28482,P22681,P60953,Q8NC96,Q92974,P63241,Q9BPU6,Q01433 34 +St segment elevation 0.5789669688336405 1.4390387465062051 0.1501395451078717 1.0 0.4334128420416849 3 Q99996 1 +Duplication of thumb phalanx 0.6385233149378817 1.4364333875861428 0.1508790583403625 1.0 0.4347920045986976 24 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q6W2J9 12 +Impaired antigen specific response 0.6028110476669417 1.4342645833309629 0.1514967730773757 1.0 0.4362388353345408 9 O95394,P50851,P17812,P49327,Q9BV10 5 +Osteosarcoma 0.6388005914623303 1.4263730817604718 0.1537606794610979 1.0 0.4411057303196796 26 O96017,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P42771,P62899,Q13126,Q13501 15 +Abnormal pupillary function 0.5936407866631581 1.4247703917359855 0.1542235836657652 1.0 0.4420658490212015 7 Q6XZF7 1 +Gastrointestinal carcinoma 0.6409721835771076 1.422816017123096 0.1547894969149585 1.0 0.4429553035165657 32 O96017,O14965,P08708,P52701,Q07864,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,P46777,P28340 17 +Decreased palmar creases 0.5708743658609287 1.422192374079812 0.1549704119912425 1.0 0.443198084634595 2 Q8NCH0 1 +Normochromic anemia 0.6355386379048682 1.4202510094039416 0.1555346181446304 1.0 0.443985887067562 24 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Hypoplasia of the olfactory bulb 0.5693822739480667 1.4144926324445428 0.1572173090797339 1.0 0.4476811399906252 2 A6NHR9 1 +Short attention span 0.265356351107919 1.4127359230766632 0.1577333849413134 1.0 0.4483715714652442 142 P68400,Q93008,P46109,Q08209,P10589,P21359,Q01968,Q6DN90,Q5F1R6,Q9P2D1,P52701,Q9UET6,Q9ULK4,Q15058,O43709,P26196,P42858,Q13045,Q9Y296,Q08J23,Q96F07,Q96F86,P49917,O60524,Q7Z6Z7,Q9NUQ7,P60866,Q9UBB6,Q9UIG0,Q00610,Q05639,Q12830,P49589,Q06787,O75182,P28482,Q8NC96,Q9BPU6,Q9Y223,P46821,Q96C86,Q7LBC6,Q2M389,P54277 44 +Somatic mosaicism 0.5725533871199655 1.4059464553288168 0.1597400251763998 1.0 0.4527328730373494 3 P61586 1 +Long ear 0.5712652347805135 1.3992963817025843 0.1617241242307543 1.0 0.4565687791165665 3 Q7LBC6 1 +Recurrent sinopulmonary infections 0.5921792788998719 1.3977815823713309 0.1621786667001028 1.0 0.4570129440974798 8 Q86Y56,P57076,P40763 3 +Abnormal t cell subset distribution 0.6081572082919312 1.3952909866046157 0.1629281089931229 1.0 0.4582849797471195 13 O95394,O00203,P17812,P54132,P49327,Q96BN8,Q13315,Q14790 8 +Abnormality of hand joint mobility 0.5745353007435332 1.3920372219451156 0.1639111267726301 1.0 0.4602081727341099 4 Q9Y263 1 +Hyperextensibility of the finger joints 0.5745353007435332 1.3920372219451156 0.1639111267726301 1.0 0.4602081727341099 4 Q9Y263 1 +Oral cleft 0.2551772178945867 1.3859109330517594 0.1657741019590872 1.0 0.4623433690068135 169 P36507,P08708,Q9UPP1,Q07020,P62847,O15357,Q15436,Q93008,P46109,Q08209,P61353,P48651,Q13535,Q9H3P2,Q9P2D1,Q9Y4A5,Q9NVI1,Q15058,P62081,P42766,Q13045,P40763,P46777,Q6PGP7,P62244,Q08J23,Q8IWS0,Q99741,Q06124,Q9Y4X0,Q96EK5,P49917,O43505,Q9BZH6,Q9H7D7,P62854,P60866,P61313,Q8NCH0,O43924,Q5SRE5,O14802,O15111,P49589,O60826,P28482,P62266,P29372,P61254,P62899,P63241,Q14738,Q6W2J9,Q13618 54 +Nephronophthisis 0.5767622461170763 1.380250505811089 0.1675095282802399 1.0 0.4652146020209191 5 Q8TD19,Q16658,Q96EX3,Q8NCM8 4 +Abducens palsy 0.5712604073116415 1.3751212030992748 0.1690938718996859 1.0 0.4684865051490998 4 O00170 1 +Hematological neoplasm 0.4013160387224867 1.3719823994471 0.1700689170127587 1.0 0.4687660654720015 89 P08708,Q07020,P62847,Q5TBB1,P61353,P42771,P21359,P49327,Q5F1R6,Q9P2D1,Q9Y3Z3,Q9NVI1,P52701,P62081,O76094,P17812,P42766,P40763,P46777,Q06124,P49917,Q07864,P62854,P60866,P61313,Q9Y620,Q13315,Q9UDY8,O96017,P22681,P50851,P61254,P62899 33 +Cessation of head growth 0.583245705755104 1.3709802637644957 0.1703811085331861 1.0 0.4687660654720015 7 Q05086,Q13144,P49770,Q9Y263 4 +Infertility 0.6088349397101107 1.3698970117042018 0.1707190526756909 1.0 0.4687660654720015 15 Q06124,P57076,Q9BZH6,P40818,Q8IY37,P54132,Q96RD7,Q86Y56 8 +Monotonic speech 0.5828875344591041 1.3691261073420569 0.1709598587732399 1.0 0.4688691013798786 7 O75165,Q69YN2,Q04637,Q9Y3I1 4 +Abnormal speech prosody 0.5828875344591041 1.3691261073420569 0.1709598587732399 1.0 0.4688691013798786 7 O75165,Q69YN2,Q04637,Q9Y3I1 4 +Diaphragmatic eventration 0.5685968717708652 1.361359382668947 0.1734001453521361 1.0 0.4732307151704827 4 P38935 1 +Polyphagia 0.5885748241465562 1.3603845079577253 0.1737082783240353 1.0 0.4732307151704827 9 Q3SYG4 1 +Unusual fungal infection 0.5942126350801087 1.35453281965528 0.1755664500402045 1.0 0.4752433481004748 11 O95394,O00203,P40818,Q9Y5L0,P40763 5 +Central primitive neuroectodermal tumor 0.5660698437100649 1.3483003477432205 0.1775618003386436 1.0 0.4790015116737796 4 P42771 1 +Abnormal circulating iga level 0.6089319926419929 1.3443748122628127 0.1788272145387701 1.0 0.4809476537693529 17 O95394,P68400,P42345,P50851,Q00653,Q9Y5L0,P54132,P49327,Q96BN8,Q13315,Q9BV10 11 +Soft doughy skin 0.5580002489413121 1.330765281494777 0.1832662550897867 1.0 0.4901365731933776 3 P41252 1 +Abnormality of male internal genitalia 0.5863266253938664 1.3307136782721165 0.183283240571987 1.0 0.4901365731933776 10 O96017,Q8IWS0,P42771 3 +Enamel hypoplasia 0.6012092484687135 1.3298064137723695 0.183582062192001 1.0 0.4906512473300699 15 O00443,O43933,P21359,Q01968,Q13535,Q5F1R6,P18074 7 +Abnormality of the pubic bone 0.5746295369851693 1.3263691097006718 0.1847174655121766 1.0 0.4931143914396242 7 Q14999,O15357 2 +Postaxial hand polydactyly 0.5882357746320324 1.3233935930734415 0.1857045213266772 1.0 0.4948902119468297 11 Q3SYG4 1 +Neurogenic bladder 0.576989942150953 1.3190433960275103 0.1871546049443058 1.0 0.4973180832995867 8 Q9Y3I1 1 +Abnormality of vitamin a metabolism 0.5688680311177698 1.3168784494276249 0.1878793712524669 1.0 0.4989565570452676 6 Q9NSD9,Q13043,Q5F1R6 3 +Bell shaped thorax 0.5675139708093643 1.3098742695639085 0.1902383728853856 1.0 0.5029052229915666 6 O43933 1 +Abnormality of the musculature of the limbs 0.2532663061562479 1.3031637262584062 0.1925188711248231 1.0 0.5081317123798812 165 P08708,Q07020,P62847,Q9Y263,P61353,P21359,P42356,P38935,Q13126,P42695,Q14999,P62081,P42766,Q9Y5L0,Q14204,Q96IJ6,Q96F07,Q06210,Q06124,Q9NZJ4,P50570,P62854,P60866,P61313,Q00610,O95248,O14802,Q13501,O60333,O60231,P40818,P62899,Q8NCE2 33 +Abnormal hemoglobin 0.6148313192943325 1.295375463135359 0.1951907382323394 1.0 0.511890207769063 26 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q5F1R6 12 +Abnormal morphology of the limbic system 0.5882947193232657 1.2913861050168929 0.1965698263722899 1.0 0.5150419745295757 13 Q00610,P10589,Q14204,Q9UID3,P67870,Q9BPU6 6 +Metaphyseal dysplasia 0.5806886440557466 1.284082213628173 0.1991131907202814 1.0 0.5195187493171144 11 Q9HC07,Q07864,Q99575,O00443 4 +Decreased lacrimation 0.5661662205136687 1.2825469290806188 0.1996508535118626 1.0 0.5203329871470183 7 Q10567,O95163,Q96IJ6 3 +Clubbing 0.6012747226715561 1.280539158839208 0.2003555819406051 1.0 0.521013633389595 19 P57076,P26639,P50851,Q9H4L7,Q9UID3,Q86Y56,P18074,Q9NVI1 8 +Abnormality of neutrophil physiology 0.5557555761809618 1.271649417853968 0.2034977100550361 1.0 0.5261967132757185 5 P06744,Q5F1R6 2 +Panniculitis 0.5699412643699943 1.263652021357445 0.2063549529642621 1.0 0.5305530875165895 9 P49327,Q969U7,Q5TBB1,Q96BN8 4 +Lewy bodies 0.5578792362300563 1.2600429746375397 0.2076538598915958 1.0 0.5309907182261261 6 O75165,Q04637,Q9Y3I1 3 +Visual hallucinations 0.5578792362300563 1.2600429746375397 0.2076538598915958 1.0 0.5309907182261261 6 O75165,Q04637,Q9Y3I1 3 +Albuminuria 0.5566269309436512 1.2535678271718151 0.2099991312988796 1.0 0.5349121991616409 6 Q9UBS4,O43933 2 +Abnormality of immune serum protein physiology 0.5601032158405885 1.2511634627640564 0.2108748455129108 1.0 0.5358158537054166 7 P49327,Q5TBB1,Q9Y3Z3 3 +Cavernous hemangioma 0.5554868462261892 1.2476734948499553 0.2121506516038114 1.0 0.538608120995257 6 P50570,Q8NCE2 2 +Abnormality of the hypothenar eminence 0.5455957654619952 1.2424697044565691 0.2140633115321435 1.0 0.5416752913317489 4 Q7Z392,Q96IJ6 2 +Abnormality of the philtrum 0.233302259402494 1.2396080723741445 0.2151203934356487 1.0 0.5423546365949077 218 O15357,Q9Y263,Q8IY37,O60701,Q93008,A5YKK6,O95352,P51532,P21359,Q01968,O75909,A1X283,Q4G0J3,Q9H3P2,Q9Y4A5,P57081,Q14999,O43709,P26196,P42858,Q6PGP7,Q9Y296,P27635,P67870,P78527,Q96EK5,Q7Z6Z7,P42345,O00203,Q00610,Q96N67,Q08AM6,O14802,Q9BV10,P46821,O60826,O14617,Q13555,P28482,P29372,P22681,Q15042,Q6W2J9,Q9UID3,Q9BPU6 45 +Glaucoma 0.3134920446707509 1.2390657510844627 0.2153211492418063 1.0 0.5424775868118256 98 P08708,Q07020,P62847,P61353,O43933,P21359,Q01968,P49327,A1X283,Q13535,O43709,P62081,P42766,Q6PGP7,O43505,P62854,P60866,O00443,P61313,Q15477,O60826,P62899,Q6W2J9 23 +Autistic behavior 0.2380847310047192 1.235126849841448 0.2167832980995352 1.0 0.5449707651951804 201 Q9NPL8,Q93008,O95352,P10589,P21359,Q5F1R6,Q9P2D1,Q9Y4A5,Q9Y6D5,Q8IUX1,O43709,P26196,P42858,P41252,Q14204,Q9Y296,Q96F07,P27635,P67870,Q96F86,O00217,Q14353,Q9BUK6,O60524,Q7Z6Z7,P42345,Q96N67,Q13501,Q9HCK8,O75182,O14646,P62266,Q9BPU6,Q6W2J9,P46821,Q96C86,Q15334,Q7LBC6,Q2M389 39 +Abnormal cardiac atrium morphology 0.2535631620748266 1.2330446471681575 0.2175591072225384 1.0 0.5464837268100255 155 Q2VPK5,P08708,Q07020,P62847,P61353,Q93008,P51532,P21359,A1X283,Q4G0J3,Q9H3P2,Q86Y56,Q9P2D1,Q9Y4A5,Q9NVI1,O43709,P62081,P26196,P42766,Q14839,Q6PGP7,P46777,P27635,Q06124,Q9Y4X0,P62854,P60866,P61313,Q08AM6,Q9BV10,Q15477,O60826,P28482,P31939,P61254,P62899,Q6W2J9 37 +Decreased circulating iga level 0.5707894018185949 1.2325584806739005 0.2177405354166111 1.0 0.5464837268100255 11 P68400,P42345,P50851,Q00653,P54132,Q13315 6 +Abnormal testis morphology 0.2303171631953294 1.2265815089421617 0.2199799226311249 1.0 0.5503076914844791 233 Q3SYG4,Q9UPP1,O15357,Q8IY37,O43933,P51532,P42771,P21359,Q01968,P49327,Q13535,P28340,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,Q14999,O43709,P26196,Q14839,P42858,Q01844,Q9Y296,P27635,P18074,Q8IWS0,Q06124,P49917,O43505,Q07864,Q7Z6Z7,P26639,P42345,P50570,O00443,Q08AM6,O14802,Q13315,Q9BV10,O96017,O60826,P28482,P29372,P22681,Q15042,Q7LBC6,P63241,Q6W2J9,Q9BTW9,Q9BPU6,Q8NCE2 51 +Pulmonary artery stenosis 0.5837372437956171 1.2243462340074762 0.2208216426286533 1.0 0.5518423191068191 16 Q06124,O43709,P22681,Q6PGP7,P27635,Q6W2J9,Q15477 7 +Oligomenorrhea 0.5542322161582159 1.2207907657328576 0.2221652510102125 1.0 0.5528919305087151 7 O00170,P31751 2 +Severe viral infection 0.5538660598096065 1.218897248159432 0.2228831942752274 1.0 0.5542642453863202 7 P17812,P29144,O95394,P54132 4 +Dimple chin 0.5362690103775604 1.218439408490538 0.2230570370781284 1.0 0.5542850435304784 3 Q9P2D1 1 +Nonspherocytic hemolytic anemia 0.536106305482869 1.2175988769837087 0.2233764414053043 1.0 0.5542850435304784 3 P06744 1 +Abnormality of vitamin e metabolism 0.5452376816647042 1.2172940861066837 0.2234923435869693 1.0 0.5542850435304784 5 Q13043,Q5F1R6 2 +Positive romberg sign 0.5554879494114769 1.2076365845665276 0.2271870805124911 1.0 0.5604352954032736 8 O14802 1 +Abnormal granulocytopoietic cell morphology 0.5335686200601204 1.204491207103287 0.2283997785706064 1.0 0.5616334797116632 3 Q07020 1 +Neoplasm of the colon 0.5994227655423183 1.2044820993052834 0.2284032967567917 1.0 0.5616334797116632 40 O96017,P52701,P08708,Q07864,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P20585,P42771,P61313,P62899,P28340,P54277 18 +Aplasia hypoplasia of the capital femoral epiphysis 0.5467927277783987 1.20274823261416 0.2290737629255295 1.0 0.5629820289693488 6 Q8WVQ1,O00443,Q99741 3 +Abnormal ventricular septum morphology 0.2523514051888299 1.1967671491896026 0.231397325894572 1.0 0.5668804377863308 153 Q2VPK5,P08708,Q07020,P62847,P61353,O43933,P51532,P21359,Q7KZN9,A1X283,Q9P2D1,Q9NVI1,O43709,P62081,P42766,Q14839,Q6PGP7,P46777,P27635,O00217,P18074,Q06124,P26639,P62854,P60866,P61313,Q08AM6,Q5SRE5,Q9BV10,Q15477,O60826,P28482,P61254,P62899,Q6W2J9,Q7LBC6 36 +Cutaneous melanoma 0.5363283738560326 1.1946037881695133 0.2322418684956289 1.0 0.5686474200479491 4 P42771 1 +Tapered finger 0.5957562002324378 1.1886080847706273 0.2345939249558464 1.0 0.5722801564364461 41 Q9Y4X0,Q96EK5,P28482,Q7Z6Z7,O00170,Q93008,A5YKK6,Q14839,P10589,Q08AM6,Q9H4L7,P53618,O75909,P46821,P27635,Q9BPU6,Q8IWS0 17 +Abnormal number of erythroid precursors 0.5948902794323657 1.1867945184618616 0.2353086815340959 1.0 0.5730940704523183 26 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Aplasia of the fingers 0.5966756509838392 1.181870148334816 0.2372572283841556 1.0 0.5754298604290798 29 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q08AM6,Q9P2D1,Q9NVI1 14 +Developmental glaucoma 0.5971285470982636 1.1783886145521407 0.2386417145979589 1.0 0.5772701779970553 31 P08708,Q07020,P62847,P62081,P61353,Q5TBB1,P62854,P42766,P60866,P61313,P61254,Q01968,P62899,A1X283,P46777 15 +Increased hepatic glycogen content 0.5368731268528935 1.1741161638228397 0.2403484999692264 1.0 0.5802290195553983 5 P31751,P06737 2 +Chorioretinal dysplasia 0.5320463909781257 1.1725081546433007 0.2409931000758711 1.0 0.5804802866454576 4 Q01968 1 +Abnormal renal resorption 0.5272909917399021 1.1720854567515244 0.241162748206106 1.0 0.5804802866454576 3 Q01968 1 +Renal fanconi syndrome 0.5272909917399021 1.1720854567515244 0.241162748206106 1.0 0.5804802866454576 3 Q01968 1 +Macrocytic anemia 0.5957713545313575 1.171515891986601 0.2413914737395979 1.0 0.5804802866454576 37 P00374,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,Q99707,P61313,P61254,P62899,Q5F1R6 14 +Eeg with multifocal slow activity 0.5515006773090501 1.168089650749322 0.2427706044445361 1.0 0.5823717099857749 9 Q96F07,Q05639,Q8NC96,Q00610 4 +Cataplexy 0.5306530330911656 1.165321907033647 0.2438887147360517 1.0 0.5847498134497957 4 P26358 1 +Gingival fibromatosis 0.5251758792017008 1.161174692743175 0.2455708642537066 1.0 0.587561409129849 3 Q15392 1 +Anosmia 0.5341108464815234 1.1598714879567544 0.2461011327528277 1.0 0.5882199613413442 5 Q9P2D1,Q9BZH6 2 +Respiratory failure requiring assisted ventilation 0.5420840669538011 1.1580326769980538 0.2468507015878478 1.0 0.5888176506698596 7 P38935 1 +Ependymoma 0.5337488911760966 1.1580055583378737 0.246861768132562 1.0 0.5888176506698596 5 P42771 1 +Abnormal eyebrow morphology 0.2446140265417442 1.154116541045351 0.248452392758796 1.0 0.591693798552569 169 Q2VPK5,Q3SYG4,Q9UPP1,O00170,O60701,O43933,P51532,P21359,P49327,O75909,Q4G0J3,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,Q14999,P26196,P42858,P46778,Q9Y296,Q96F07,Q8IWS0,Q9Y4X0,Q96EK5,P49917,Q7Z6Z7,Q96N67,Q08AM6,Q5SRE5,O14802,Q69YN2,Q13555,O14646,P62266,P28482,P63241,Q6W2J9,P46821,Q9BTW9,Q9BPU6 40 +Protuberant abdomen 0.5322397987507657 1.1502276297494076 0.2500501291028016 1.0 0.5942837594030608 5 P42345,O15357 2 +Myokymia 0.5177558937630441 1.1477364534257857 0.2510773776168475 1.0 0.5960987868999063 2 O15020 1 +Posteriorly rotated ears 0.2539566478572282 1.1417799699015512 0.2535454901921494 1.0 0.6001053598031737 119 Q3SYG4,Q9Y263,Q93008,O43933,P21359,Q01968,O75909,Q9P2D1,Q9Y4A5,O43709,Q06124,P49917,O43505,Q07864,Q7Z6Z7,O00203,P62854,O14802,O60231,P28482,Q9HC07,Q15042,P46821,Q6W2J9 24 +Neuronal loss in basal ganglia 0.5304896731415668 1.1412109037568652 0.253782167918164 1.0 0.6003575080033284 5 P42858 1 +Acanthocytosis 0.5251989348845304 1.1372128903882088 0.2554492995307049 1.0 0.6030642879913725 4 Q9Y6B6 1 +Impaired visuospatial constructive cognition 0.5400375677321084 1.1278129205212757 0.2593989355625699 1.0 0.6096209485994559 8 P42858 1 +Lethal skeletal dysplasia 0.5186948097181433 1.1277725679795372 0.259415981378871 1.0 0.6096209485994559 3 Q8NCM8 1 +Abnormal pelvis bone ossification 0.5186948097181433 1.1277725679795372 0.259415981378871 1.0 0.6096209485994559 3 Q8NCM8 1 +Ulnar deviation of the hand or of fingers of the hand 0.5596970945225519 1.1268921469159496 0.2597880840479774 1.0 0.6101845375322401 14 O43933,Q9BPU6,Q15042 3 +Abnormal b cell morphology 0.5562501135133583 1.1242810937860732 0.2608937963463607 1.0 0.611536119179757 13 P50851,P17812,Q00653,P49327,Q9BV10,Q96Q11 6 +Short femur 0.5354155767616147 1.1236562977814926 0.2611588629266688 1.0 0.6116211164421227 7 Q9Y4X0,O14802 2 +Abdominal obesity 0.5314264590196216 1.123515380014838 0.2612186723113978 1.0 0.6116211164421227 6 O00170,P40818,P54132 3 +Alacrima 0.5308684969439484 1.120644091509654 0.2624393890234806 1.0 0.612978684336869 6 O95163,Q96IJ6 2 +Abnormal eosinophil morphology 0.5443143847435117 1.1127496382179491 0.265815970305765 1.0 0.620237264046785 10 P49327,P49917,P40763,Q9P2D1 4 +Clubbing of fingers 0.5244128411934803 1.109935538151091 0.2670268051422222 1.0 0.6227475491006426 5 P50851 1 +Prostate neoplasm 0.5317717719595192 1.1049009884532166 0.2692024940841002 1.0 0.626870825446721 7 P42771 1 +Macrodontia 0.5697963245393148 1.1028906670745526 0.2700746476909508 1.0 0.6282674482089542 20 Q7Z6Z7,Q8IY37,P42858,Q9UID3,Q9BPU6,Q9Y296 6 +Bilateral polymicrogyria 0.5384704559170979 1.1008080611770257 0.270980202585843 1.0 0.6291050198935549 9 Q05639,Q00610,P42356,Q14204,P67870 5 +Neoplasm of the tracheobronchial system 0.5130592125219067 1.0987728252078086 0.2718671682048681 1.0 0.6303218841830341 3 Q14790 1 +Diminished ability to concentrate 0.5122388059701576 1.0945552270430636 0.2737115397900103 1.0 0.6330460828622259 3 Q01082,Q96RR1 2 +Shield chest 0.516295451060117 1.0914129732625677 0.2750912064410431 1.0 0.6348152752939129 4 Q99575 1 +Germ cell neoplasia 0.5428308649045576 1.0876115399453292 0.2767666341238266 1.0 0.6380432199966078 11 O96017,Q8IY37,P42771 3 +Abnormally ossified vertebrae 0.5200013003094828 1.087267439446091 0.2769186340583434 1.0 0.6380747547008682 5 Q8NCM8,O15357 2 +Abnormality of the fetal cardiovascular system 0.5235767890706096 1.083168517363852 0.2787336309838846 1.0 0.6398362841685579 6 O60826,P26196 2 +Recurrent viral infections 0.5588171368295596 1.0806015715345303 0.2798743831827739 1.0 0.6399255466839942 17 O95394,Q13432,P17812,P29144,Q00653,P54132,Q5F1R6,Q14790,Q9UDY8 9 +Astrocytoma 0.5379306192759968 1.0798278190762187 0.2802188606767111 1.0 0.6399255466839942 10 O96017,P21359,P20585,P42771 4 +Abnormal vascular morphology 0.2247889004559626 1.0785213537758382 0.2808011574808331 1.0 0.6400413798011649 232 Q2VPK5,P08708,Q07020,P62847,P61353,Q93008,O43933,P51532,P21359,P49327,A1X283,Q86Y56,Q9P2D1,Q9Y4A5,Q9Y6D5,Q9NVI1,O43709,P62081,P26196,P42766,P42858,Q14839,Q96BN8,P40763,P46777,Q6PGP7,Q9UBS4,Q9Y296,P27635,P18074,Q92908,Q9Y4X0,Q06124,Q7Z6Z7,P62854,P60866,P61313,Q08AM6,O14802,Q9BV10,Q15477,O15111,O60333,O60826,P57076,Q06787,P28482,P22681,P61254,P62899,Q7LBC6,Q6W2J9,P46821,Q9BPU6 54 +Decreased number of large peripheral myelinated nerve fibers 0.518170403615803 1.077869884968647 0.281091826512124 1.0 0.6400413798011649 5 Q9NZJ4 1 +Abnormality of the musculature of the hand 0.5793866048225276 1.0778469413786953 0.2811020670880468 1.0 0.6400413798011649 37 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,P46777,Q9Y223,Q96IJ6,Q13501 15 +Abnormal hair laboratory examination 0.5301272421644152 1.0768003364023662 0.2815694750198032 1.0 0.6403239540515185 8 Q6PGP7,P18074,O43933,Q15477 4 +Colitis 0.5399915829319699 1.0729668086797597 0.2832860085210285 1.0 0.6424250064157944 11 P49327,P50851,Q15477 3 +Abnormal reticulocyte morphology 0.5787294528282388 1.0727076276770375 0.2834023169425843 1.0 0.6424250064157944 33 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,P49327,P08237 13 +Neoplasm of the large intestine 0.567416841500275 1.068286546395387 0.2853912752927854 1.0 0.6456645183548892 47 P08708,Q07020,P62847,P61353,P20585,P42771,P28340,O14965,P52701,P62081,P42766,P46777,Q07864,P62854,P60866,P61313,O96017,P61254,P62899,P54277 20 +Abnormal circulating creatinine concentration 0.520482586943409 1.0672958336876672 0.2858382688723992 1.0 0.6463587913276362 6 O95163,Q9UBS4 2 +Self mutilation 0.534802403828885 1.0637267908495498 0.2874524842239179 1.0 0.64847677260763 10 O95352,Q6W2J9 2 +Csf pleocytosis 0.5141661500500289 1.0573401442013548 0.2903563782123142 1.0 0.6540107288542019 5 Q5TBB1,Q9Y3Z3 2 +Csf lymphocytic pleiocytosis 0.5141661500500289 1.0573401442013548 0.2903563782123142 1.0 0.6540107288542019 5 Q5TBB1,Q9Y3Z3 2 +Supernumerary tooth 0.5259666718131591 1.0554428323335712 0.2912228421877123 1.0 0.6556422503718482 8 Q9Y4X0,P62266 2 +Pancreatic adenocarcinoma 0.5329013197739929 1.0539529981225304 0.2919044367083736 1.0 0.6568561787979158 10 P52701,P54277,P42771 3 +Onion bulb formation 0.5357118740937737 1.0509280443775486 0.2932916389784079 1.0 0.659655938862699 11 O95248,Q5TAQ9,Q9NZJ4,O60333 4 +Bronchiectasis 0.559486680796365 1.0486296873465593 0.2943485868301094 1.0 0.6613882274950292 20 P57076,O95394,Q13432,P50851,Q00653,P29144,Q03518,P54132,Q13315,Q86Y56,Q86TI2 11 +Irregular femoral epiphysis 0.5065791519075924 1.041591450961995 0.2976011339289865 1.0 0.6670719294530685 4 P26373,Q99741 2 +Irregular epiphyses 0.5149064036052937 1.038743097934654 0.2989242315072813 1.0 0.6685171209895338 6 Q9NR45,P26373,Q99741 3 +Peripheral pulmonary artery stenosis 0.5288918548754531 1.033369370034046 0.3014310749070734 1.0 0.6730404397610502 10 Q6W2J9,O43709,Q15477 3 +Congenital nonbullous ichthyosiform erythroderma 0.509356290839856 1.0327262930662038 0.3017320053512593 1.0 0.6733864251017703 5 P18074 1 +Abnormal cell proliferation 0.5042913807703656 1.0298901167129868 0.3030615907354956 1.0 0.6753734869868799 4 P17812 1 +Abnormal vitamin b12 level 0.5085334316329788 1.0285208992245292 0.3037048651095597 1.0 0.6761537368486482 5 Q99707 1 +Prominent occiput 0.5337481511788483 1.024067038095453 0.3058036119537861 1.0 0.6796903272207347 12 O60826,A5YKK6 2 +Biconcave vertebral bodies 0.5115096701595876 1.021386542979582 0.3070713384544454 1.0 0.6813468418905035 6 O00170,P40818 2 +Fat malabsorption 0.522444706924485 1.018517547897989 0.3084320658362709 1.0 0.6830519057622265 9 Q9Y6B6 1 +Cerebral cortical atrophy 0.2802443187527023 1.014373406828362 0.3104046087176972 1.0 0.6851987155816845 100 Q9Y263,O75165,Q9Y4A5,O43709,P26196,P42858,Q9Y296,P26640,P18074,Q7Z6Z7,Q9NZJ4,P26639,Q96N67,O14802,Q13501,Q9NW08,Q15042,Q9BTW9,Q9BPU6,Q01433 20 +Adrenocortical carcinoma 0.5012276502970056 1.0142399806129456 0.3104682554665032 1.0 0.6851987155816845 4 P42771 1 +Broad eyebrow 0.5348587919703747 1.0137133793717024 0.3107195379900744 1.0 0.6851987155816845 13 Q12830,P28482,O14646,P63241,P09884,O14802,Q96C36 7 +Abnormal systemic arterial morphology 0.2447650557125893 1.0123844893778051 0.311354251581021 1.0 0.6851987155816845 144 P08708,Q07020,P62847,P61353,P21359,Q9P2D1,Q9Y4A5,Q9Y6D5,O43709,P62081,P26196,P42766,P42858,Q14839,Q9UBS4,Q9Y296,P18074,Q06124,Q7Z6Z7,P62854,P61313,Q08AM6,O60333,P28482,P62899,Q6W2J9,P46821,Q9BPU6 28 +Abnormal urine phosphate concentration 0.5047150347238838 1.0090288330872483 0.3129608064396123 1.0 0.6870641001410545 5 Q01968 1 +Decreased circulating igg level 0.5412708693986528 1.0027262574273523 0.3159929573333073 1.0 0.6913519925724115 16 P98170,P68400,P50851,P17812,Q00653,P54132,P49327,Q13315,Q14790,P18074 10 +Pulmonary artery dilatation 0.5382514524117837 1.001133898963444 0.3167620782636751 1.0 0.6918671718893623 15 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Thrombocytosis 0.5628613956698413 0.9974354494433996 0.3185531915956523 1.0 0.6947502319373391 29 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q6PGP7,Q15477 13 +Gout 0.4973402864867161 0.9944181191130264 0.3200193505257789 1.0 0.6970015410648811 4 P08237,Q9UBS4 2 +Abnormal serum iron concentration 0.5015627411263591 0.9929669273709067 0.3207260719901001 1.0 0.6982111232139367 5 Q6PGP7,Q15477 2 +Cerebellar vermis atrophy 0.533606209577957 0.9919131313418296 0.3212399028938502 1.0 0.6989998453062881 14 P47897,Q9NUW8,Q9UHD1,Q9NZJ4,P42858,Q13620,Q15334 7 +Pituitary growth hormone cell adenoma 0.4966422883264362 0.9908634602816844 0.321752256686691 1.0 0.6996637748700001 4 Q9UBS4 1 +Renal hypoplasia aplasia 0.3741434784960424 0.9890670116675234 0.3226303563187001 1.0 0.7010333649072837 88 Q2VPK5,P08708,Q07020,P62847,P61353,P21359,Q9P2D1,Q9Y4A5,P42695,Q9NVI1,O43709,P62081,P42766,Q6PGP7,Q00534,Q06124,P57678,P62854,P60866,O00443,P61313,Q92917,Q15477,P61254,P62899,Q6W2J9 26 +Celiac disease 0.4961863934300736 0.988542510996896 0.3228870254748768 1.0 0.701251579069509 4 Q9Y5L0 1 +Abnormal blood gas level 0.496014584481193 0.9876679939704692 0.3233152743094272 1.0 0.701251579069509 4 A5YKK6 1 +Recurrent skin infections 0.535626116901558 0.9876198753521228 0.3233388486193032 1.0 0.701251579069509 15 O95394,O00203,P40818,Q8NCH0,P40763,O14802 6 +Nonprogressive 0.5085125093474662 0.9858462679020008 0.3242085574040496 1.0 0.7021474531947798 7 Q9NQZ5,Q69YN2,Q06210 3 +Abnormal renal morphology 0.2160925304089364 0.9852882109530208 0.3244825218316118 1.0 0.702362839444777 263 P08708,Q3SYG4,Q07020,P62847,O00170,P61353,Q93008,O43933,P20585,P21359,Q01968,P49327,Q5F1R6,Q9P2R3,Q9P2D1,Q9Y4A5,Q9Y5K6,P42695,O43709,P62081,P26196,P42766,P41252,Q6PGP7,Q9UBS4,Q00534,Q06124,Q9Y4X0,P49917,O43505,Q07864,P57678,P53621,P62854,P60866,O00443,P61313,Q08AM6,O14802,Q92917,Q15477,O15111,O60333,O60826,O60231,P28482,P40818,Q15042,P62899,Q6W2J9 50 +Renovascular hypertension 0.5158837538868257 0.9850235077197368 0.3246125241049782 1.0 0.702362839444777 9 Q08AM6,P21359 2 +Medulloblastoma 0.5029430914757597 0.9777536638747492 0.3281961732658014 1.0 0.7077928692263403 6 P42771 1 +Ulnar deviation of finger 0.5104768327801837 0.9763198660090182 0.3289059782600481 1.0 0.7083514723314553 8 Q15042,P28482 2 +Hyporeflexia of upper limbs 0.4843330349149385 0.9762971468860616 0.3289172334177763 1.0 0.7083514723314553 2 Q15067 1 +Recurrent hypoglycemia 0.4980263982098301 0.974982946001758 0.3295687194527379 1.0 0.708901572223575 5 Q16512,Q00653,Q9BV10 3 +Abnormal natural killer cell physiology 0.4877732052900085 0.969432101637558 0.3323296420443038 1.0 0.7137042079843452 3 O00203 1 +Freckling 0.5256693264351747 0.9666169667422598 0.3337355496231033 1.0 0.7156995365410741 13 P52701,P21359,P18074,P42771 4 +Severe infection 0.5085108859964492 0.9663294750398592 0.3338793415643597 1.0 0.7156995365410741 8 P17812,P29144,O95394,P54132 4 +Intermittent diarrhea 0.5039727304670886 0.9627820332177368 0.3356569189885616 1.0 0.7186149657311064 7 Q9UER7,P42771 2 +Eyelid myoclonus 0.5149363810292531 0.9620905122813674 0.3360041395784585 1.0 0.7189179479941694 10 P00374,P67870,Q14204,Q00610 4 +Missing ribs 0.5181417112840202 0.9609914038779168 0.3365564900319431 1.0 0.7195581842185894 11 O60826,Q13535 2 +Narrow nose 0.4995370419419046 0.9604679111849254 0.3368197734221247 1.0 0.7195581842185894 6 Q07864 1 +Abnormal t cell morphology 0.5355550636399624 0.9599565667244724 0.3370770748654046 1.0 0.7195581842185894 17 O95394,O00203,P17812,P54132,P49327,Q96BN8,Q13315,Q14790 8 +Abnormal circulating igg level 0.5424345056259869 0.9596343414275356 0.337239279054973 1.0 0.7195581842185894 20 P98170,O95394,P68400,P50851,P17812,P29144,Q00653,P54132,P49327,Q14790,Q13315,Q9BV10,P18074 13 +Erythematous plaque 0.4807520143240683 0.9580859543979492 0.3380194174158482 1.0 0.720556179546815 2 P00338 1 +Atrophy degeneration affecting the brainstem 0.5174546557903398 0.9574952943935564 0.3383173203679126 1.0 0.7206555928787275 11 Q9BTW9,P26358 2 +Optic disc coloboma 0.4893194069129507 0.9536602345876704 0.3402556550469819 1.0 0.722752538071843 4 Q6W2J9,P78318 2 +Abnormality of the alveolar ridges 0.5021549632957405 0.9535664053031444 0.3403031677199313 1.0 0.722752538071843 7 Q08AM6 1 +Elevated urinary delta aminolevulinic acid 0.4889058697719846 0.951564482499656 0.341317901497403 1.0 0.7229331746380602 4 P50336,P16930 2 +Speech articulation difficulties 0.4977257110677047 0.951291328047823 0.3414565079318734 1.0 0.7229331746380602 6 P42858 1 +Abnormality of hair growth 0.4975328742899533 0.9503150526340236 0.3419521926239084 1.0 0.7229331746380602 6 P46778 1 +Glioma 0.5310307314511231 0.950033762088318 0.3420950977634756 1.0 0.7229331746380602 16 O96017,P52701,P20585,P21359,P42771,P54277 6 +Abnormal serum interferon level 0.4974514214523051 0.9499027207107056 0.3421616842698758 1.0 0.7229331746380602 6 Q5TBB1,Q9Y3Z3 2 +Decreased corneal reflex 0.4885021161896529 0.9495188778758394 0.3423567753506116 1.0 0.7229331746380602 4 O95163 1 +Clinodactyly 0.2404525056821818 0.9493836289210248 0.3424255336189381 1.0 0.7229331746380602 151 Q93008,O95352,P51532,O43776,A1X283,Q13535,Q9P2D1,Q9Y4A5,Q9NVI1,P57081,Q14999,O43709,P26196,P42858,Q9Y296,P27635,Q06124,Q9Y4X0,Q96EK5,P49917,Q07864,Q7Z6Z7,O00443,Q5SRE5,Q9BV10,O75182,O60826,P28482,P22681,Q6W2J9,P46821,Q9BPU6 32 +Hypomimic face 0.5117614316728303 0.945965821616916 0.3441660191438394 1.0 0.7256114471254712 10 Q9Y3I1,Q9Y263 2 +Squamous cell carcinoma of the skin 0.487601026944157 0.9449555772763576 0.3446815556807889 1.0 0.7260347106646025 4 Q9H4L7 1 +Minicore myopathy 0.4780662488809171 0.9444545985915228 0.3449373921247658 1.0 0.7262419853361683 2 Q9Y281 1 +Craniofacial osteosclerosis 0.4765741569680551 0.9368922027818726 0.3488140104023411 1.0 0.7323982840172962 2 Q15813 1 +Cutaneous syndactyly 0.5095986781453823 0.9350037918797066 0.3497863452746474 1.0 0.7334383685236131 10 Q9H4L7,P27635,O15111 3 +Abnormal facial shape 0.2091381428143271 0.9324703527741908 0.3510935013767007 1.0 0.7358447623129125 312 P08708,Q9UPP1,Q9Y263,O00170,Q8IY37,Q93008,A5YKK6,O95352,O43933,P10589,P21359,Q01968,P51532,A1X283,Q13535,Q4G0J3,Q5F1R6,Q9P2D1,Q9NVI1,P57081,Q9NR45,Q9NRZ9,Q9ULK4,Q14999,O43709,P26196,Q14839,P42858,P41252,Q14204,Q6PGP7,Q9Y296,P27635,P26640,P67870,Q96F86,P18074,Q8IWS0,Q06210,P04350,Q9Y4X0,Q9BUK6,Q06124,P49917,Q07864,Q7Z6Z7,O60524,O94903,P26639,P42345,O00203,O00443,Q00610,O14802,Q9BV10,Q15477,Q16512,O75182,Q13555,P28482,P22681,P40818,Q6W2J9,Q96C86,Q9BPU6,Q2M389 66 +Molar tooth sign on mri 0.4843443506396485 0.928487319190526 0.3531548426252235 1.0 0.7388468069634836 4 Q96KP1,O43924 2 +Prominent digit pad 0.5358713214560041 0.9256906201836318 0.3546067838231677 1.0 0.7408003076406312 20 P62266,Q7Z6Z7,Q9BPU6,P42858,Q9Y296,Q6W2J9,P46821 7 +Breast hypoplasia 0.4921332591092143 0.9230338790102864 0.3559895501387882 1.0 0.7426426511276714 6 Q93008 1 +Abnormal tendon morphology 0.2212298046079957 0.9228068758256016 0.3561078569899001 1.0 0.7426426511276714 216 Q9Y263,O43933,P42356,Q01968,O43776,P38935,Q13535,A1X283,P28340,Q9P2D1,P57081,P52701,Q9Y5L0,P27635,P18074,Q8IWS0,Q06210,Q7Z6Z7,P26639,P50570,P60866,O00443,Q99575,Q9H4L7,Q5SRE5,O14802,Q92917,O60826,O60231,P28482,Q15042,P35251,Q99986,Q9BTW9,Q6W2J9,Q8NCE2,P54277 37 +Accessory oral frenulum 0.478476652809661 0.9223288691253392 0.3563570599476828 1.0 0.7428265330043655 3 O15111 1 +Increased circulating igm level 0.5069100183237476 0.9214022923169752 0.3568404324155392 1.0 0.7431624897213917 10 P49327,P29144,Q9Y5L0,Q96BN8 4 +Aplasia hypoplasia of fingers 0.3071707066737591 0.9194136596338796 0.3578792472797314 1.0 0.7443178393604153 96 P08708,Q07020,P62847,P61353,Q93008,P51532,Q9H3P2,Q9P2D1,Q9NVI1,Q9UET6,Q14999,P62081,P42766,P27635,Q8IWS0,P49917,P42345,P62854,P60866,O00443,P61313,Q08AM6,O60826,P28482,P61254,P62899,Q6W2J9 27 +Webbed neck 0.5489533920071696 0.9130761390995497 0.3612024986430413 1.0 0.7498771945276101 40 P08708,Q07020,P62847,P61353,P21359,Q9P2D1,P62081,P42766,P46777,Q06124,P62854,P60866,P61313,P28482,P22681,P60953,P61254,P62899,Q6W2J9 19 +Iron deficiency anemia 0.4855723500470044 0.9119838314765142 0.3617772289932954 1.0 0.7506703518989857 5 P49327 1 +Palmar telangiectasia 0.4715010444643244 0.9112402986818162 0.3621687750845233 1.0 0.7508694649280476 2 Q13043 1 +Abnormal large intestine morphology 0.4061155033537033 0.9096011375201584 0.3630328984903244 1.0 0.7516475586785756 82 P08708,Q07020,P62847,P61353,P20585,P42771,P49327,P28340,P52701,O14965,O43709,P62081,P42766,Q6PGP7,P46777,Q92908,P49917,Q07864,P62854,P60866,P61313,Q15477,O96017,P50851,P61254,P62899,Q6W2J9,P54277 28 +Pituitary adenoma 0.5095331080513074 0.9006694716952036 0.3677640849435661 1.0 0.7587190178196201 12 P52701,O00170,P60866,Q9UBS4,P54277 5 +Cupped ear 0.5154500765205231 0.8993052605812922 0.3684900860980615 1.0 0.7598769634199186 14 Q7Z6Z7,Q14839,Q5F1R6,Q9P2D1,Q6W2J9 5 +Abnormal circulating methionine concentration 0.4872805777745739 0.8986137610682225 0.3688584263060828 1.0 0.7602966579758534 6 Q6PGP7,Q99707 2 +Intellectual disability severe 0.2392923022858778 0.8978004824918274 0.3692919274038144 1.0 0.7608502282777115 141 Q93008,O43933,P51532,Q7KZN9,P53618,Q4G0J3,Q9H3P2,Q9Y6D5,P42695,Q9NR45,Q9UET6,Q9ULK4,P42858,P40763,Q14204,Q00534,P27635,P67870,Q96F86,O00217,Q8IWS0,Q14353,Q9Y4X0,O60524,Q9UBB6,Q00610,Q16512,P31939,Q15042,Q96C86,Q9BPU6,Q2M389 32 +Intestinal polyp 0.5294082062355426 0.8924640458923185 0.372144255832096 1.0 0.7643372449481117 20 O96017,P52701,Q07864,P20585,P42771,P28340,P54277 7 +Basal ganglia calcification 0.4898732924790366 0.891631473304165 0.3725904947280574 1.0 0.7649131963420244 7 Q969U7,Q5TBB1,Q9Y3Z3 3 +Agnosia 0.4896988790324349 0.8907564507310084 0.3730598429571832 1.0 0.7655360567444334 7 P52701,P54277 2 +Breast carcinoma 0.5346564930917614 0.8894862430258142 0.3737418134155901 1.0 0.766138424109714 23 O96017,Q07864,P42771,P21359,Q13535,P28340,Q13315 7 +Peripheral cyanosis 0.4894048890323723 0.8892818282295276 0.3738516350901726 1.0 0.766138424109714 7 Q5TBB1,O95163 2 +Lymphedema 0.5161428149245274 0.8881800291902849 0.3744439194860385 1.0 0.7666710166840194 15 Q06124,P28482,P22681,O15357,P60953,Q00535,P26358 7 +Allergy 0.4885869660589548 0.8851812698549691 0.3760588726059981 1.0 0.7694677094822197 7 O14646,P42345 2 +Abnormality of iron homeostasis 0.4845715032409066 0.8850244600190567 0.3761434391680913 1.0 0.7694677094822197 6 Q6PGP7,Q15477 2 +Basal cell carcinoma 0.5029428193514626 0.8840995696609689 0.3766424654977678 1.0 0.7698437064971808 11 P49327,P52701,P18074,P54277 4 +Decreased testicular size 0.5336071439099747 0.884065211458924 0.3766610113947837 1.0 0.7698437064971808 23 O43505,Q9UPP1,Q14999,Q9P2D1,Q8IY37,P27635,P18074,Q8IWS0 8 +T lymphocytopenia 0.4956872798298596 0.8828835618570112 0.377299185952642 1.0 0.7706273995713686 9 O95394,Q13432,P49327,Q13315,Q7L590 5 +Abnormal cardiac ventricle morphology 0.2240504584416189 0.8772158916557298 0.3803693859917381 1.0 0.7746772527946525 194 O75880,Q2VPK5,P08708,Q07020,P62847,O00170,P61353,O43772,O43933,P51532,P21359,Q7KZN9,A1X283,Q9P2D1,Q9NVI1,P52701,O43709,P62081,P42766,Q14839,Q6PGP7,P46777,P35573,P27635,O00217,P18074,Q06124,P26639,P62854,P60866,P61313,Q08AM6,Q5SRE5,Q9BV10,Q15477,O60826,P28482,P61254,P62899,Q6W2J9,Q7LBC6,P54277 42 +Abnormal breath sound 0.5047323125928775 0.8764935740617824 0.3807617682267632 1.0 0.7747785204593455 12 Q86Y56,P57076,P38935 3 +Osteomyelitis 0.5165442752038685 0.8762505538959373 0.3808938391501182 1.0 0.7747785204593455 16 Q5F1R6,Q8N8R5,P40763,P26358,Q13126 5 +Abnormality of neutrophils 0.3420051615141428 0.8761969484770328 0.3809229751575538 1.0 0.7747785204593455 91 P08708,Q07020,P62847,P61353,P49327,Q5F1R6,Q9NVI1,Q9NRZ9,P62081,P42766,Q96BN8,P40763,P18074,P49917,P26639,O00203,P62854,P60866,P61313,O14617,P22681,P35579,P50851,P29144,P61254,P62899,Q6W2J9 27 +Megalocornea 0.5041542612717811 0.8735902173092264 0.3823414556182052 1.0 0.7769784734655422 12 Q96EK5,A1X283,O43709 3 +Ocular anterior segment dysgenesis 0.3191559404233691 0.8724453980117606 0.3829654433283205 1.0 0.7775614392929324 94 P36507,P08708,Q07020,P62847,Q5TBB1,P61353,P21359,Q01968,A1X283,Q9NVI1,O43709,P62081,P42766,P46777,P18074,P26639,P62854,P60866,O00443,P61313,Q5SRE5,O60333,Q15042,P62899,P61254,Q6W2J9 26 +Intractable diarrhea 0.473101540802005 0.8719575579533217 0.383231531716218 1.0 0.7777593734302305 4 Q15477 1 +Abnormality of skeletal maturation 0.2528400331066711 0.8651584434834201 0.3869518307580974 1.0 0.7839300813733437 102 O15357,O00170,Q8IY37,O43933,P10589,P51532,Q13535,Q5F1R6,Q9P2D1,P57081,Q14999,O43709,P26196,P18074,Q06124,P49917,Q9BUK6,Q7Z6Z7,P26639,O00443,Q99575,Q9UDY8,O75182,P22681 24 +Abnormal thalamic size 0.4616532378394431 0.8617416578877712 0.3888296962466062 1.0 0.786008496400363 2 Q9UPT5 1 +Generalized myoclonic atonic seizure 0.4616532378394404 0.8617416578877579 0.3888296962466135 1.0 0.786008496400363 2 Q96CW1 1 +Eeg with focal spike waves 0.4616532378394404 0.8617416578877579 0.3888296962466135 1.0 0.786008496400363 2 Q96CW1 1 +Frontal balding 0.4616532378394404 0.8617416578877579 0.3888296962466135 1.0 0.786008496400363 2 Q96CW1 1 +Aplasia hypoplasia of the scapulae 0.4752110174241264 0.8600443597880789 0.3897645902359787 1.0 0.7872881622702685 5 Q08AM6 1 +Axonal degeneration 0.4795596884748888 0.8599727437181962 0.3898040673369376 1.0 0.7872881622702685 6 P38935 1 +Duplicated collecting system 0.4782279950912282 0.8533366087572851 0.3934726641590311 1.0 0.7926154584129305 6 Q9Y4R8,Q9BXW9,P28482,P41252 4 +Kyphosis 0.2351613357500136 0.8511094927264451 0.3947085327253554 1.0 0.7947579491322848 152 Q9UPP1,Q9Y263,O00170,O95352,P21359,Q01968,O43776,A1X283,P53618,P28340,Q14999,O43709,P26196,P42858,Q9Y296,P18074,Q8IWS0,P04350,Q06124,O60524,Q7Z6Z7,O00443,Q99575,O14802,O60826,Q9HC07,Q15042,Q6W2J9,Q9BPU6 29 +B lymphocytopenia 0.496096259910145 0.8498102427090328 0.3954305940712406 1.0 0.7956212432180189 11 Q13432,P50851,Q00653,Q9BV10,Q96Q11,Q7L590 6 +Psychotic mentation 0.4722711329056036 0.8453986042552336 0.3978883235351909 1.0 0.7970065212184152 5 O00170 1 +Receptive language delay 0.5155510097312794 0.8453058035460222 0.3979401215982072 1.0 0.7970065212184152 18 Q7Z6Z7,P26196,P42858,Q9Y296,Q9BPU6 5 +Incisor macrodontia 0.512996631449522 0.8450592039319612 0.3980777844977754 1.0 0.7970065212184152 17 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Triangular shaped phalanges of the hand 0.4664224023222246 0.8436816652094411 0.3988473157457632 1.0 0.7970065212184152 69 P08708,Q07020,O15357,P62847,P61353,Q93008,A5YKK6,Q9NVI1,P62081,P26196,P42766,P42858,Q9Y296,P49917,Q7Z6Z7,P62854,P60866,P61313,Q08AM6,Q69YN2,P61254,P62899,Q6W2J9,Q9BPU6 24 +Focal non motor seizure 0.4912103182852453 0.8426332517569627 0.3994335882390014 1.0 0.7970065212184152 10 Q05639,Q00610,P42356,Q14204,P67870 5 +Large hands 0.5040933035666804 0.8421489113235948 0.39970460625858 1.0 0.7970065212184152 14 Q9UPP1,O00170,O43933,P21359,O14802 5 +Neoplasm of the male external genitalia 0.4893403901747176 0.8333346009057582 0.4046560472402245 1.0 0.8042145052821582 10 O96017,Q01844,P42771 3 +Hypotelorism 0.5345159531915098 0.8276495884824026 0.4078689762407581 1.0 0.8084264500476336 36 P57081,P49917,Q9BUK6,O14617,Q7Z6Z7,Q93008,A5YKK6,Q9BPU6,Q15042,P21359,O43776,Q9Y4A5,P18074 13 +Failure of eruption of permanent teeth 0.4591129073750014 0.8253443443186588 0.4091761227944135 1.0 0.8097509457102657 3 A6NHR9 1 +Poor fine motor coordination 0.4839843549837656 0.824540861633099 0.4096323081122999 1.0 0.8103061051981302 9 P42858 1 +Multiple cafe au lait spots 0.5031704541182308 0.822990211345001 0.4105135599577387 1.0 0.8111229563034427 15 P36507,P52701,Q9NVI1,P21359,Q15645,Q13315,Q9BXW9,O43683,O43684 9 +Ventriculomegaly 0.2218512022338773 0.8185042527843184 0.4130693146606972 1.0 0.8128417526457612 190 Q9NPL8,Q9Y263,O60701,Q93008,P51532,Q01968,Q12873,P26358,Q86Y56,Q9P2D1,P42695,Q9NVI1,Q9NR45,Q14839,P42858,P08243,Q14204,Q00534,Q96F07,P67870,P18074,Q96EK5,O43505,O94903,Q7Z6Z7,P26639,P42345,Q00610,Q5SRE5,O14802,Q9BV10,P47897,Q05639,O60826,P57076,O75182,Q15042,Q7Z460,Q6W2J9,Q9UID3,Q9BTW9,Q9BPU6,Q01433 43 +Abnormality of the dentition 0.2140482699084967 0.8179241218014903 0.4134005156220304 1.0 0.8128417526457612 235 O00170,Q8IY37,Q93008,A5YKK6,O43933,P21359,Q01968,O43776,A1X283,Q13535,P28340,Q4G0J3,Q5F1R6,Q9P2D1,P57081,Q14999,O43709,P26196,P42858,Q9Y296,Q96F07,P27635,P18074,Q06210,Q06124,Q9Y4X0,P49917,Q7Z6Z7,P26639,O00203,O00443,Q99575,Q96N67,Q08AM6,O14802,O75182,P28482,P62266,Q9NW08,Q9HC07,Q15042,Q6W2J9,Q9UID3,Q9BTW9,Q9BPU6 45 +Hypoplasia of penis 0.233583550020248 0.8149862463210409 0.4150801828380608 1.0 0.8130636447694158 109 Q3SYG4,Q8IY37,Q9P2D1,Q9Y4A5,O43709,P26196,Q14839,P18074,P78527,Q8IWS0,Q06124,P49917,O43505,Q07864,Q7Z6Z7,Q08AM6,O60826,Q15042,Q9BPU6 19 +Frontal cortical atrophy 0.5068608153522698 0.814282457422713 0.4154831570330652 1.0 0.8133477801651182 17 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Abnormal muscle fiber type distribution 0.4882631394291915 0.810891337288707 0.4174280754701565 1.0 0.8148945036579905 11 Q14204,Q8NCE2,Q06210 3 +Diffuse cerebellar atrophy 0.4715514227547095 0.8005385994735178 0.4233988089657785 1.0 0.8240065113612322 7 P18074,P26639 2 +Abnormal upper limb bone morphology 0.2311804452527719 0.8003212410912892 0.4235246994228228 1.0 0.8240065113612322 104 O15357,Q93008,A1X283,Q13535,Q9P2D1,Q14999,O43709,P26196,P42858,Q9Y296,Q06124,Q9Y4X0,P49917,Q7Z6Z7,Q08AM6,O14802,Q9BV10,P22681,Q9BPU6,P61254,Q6W2J9 21 +Neoplasm of striated muscle 0.4809836721203224 0.7920267524191292 0.4283450774803536 1.0 0.8316312468084475 10 O96017,Q9UPY3,P42771,P21359,Q15645,O43683,O43684 7 +Rhabdomyosarcoma 0.4809836721203224 0.7920267524191292 0.4283450774803536 1.0 0.8316312468084475 10 O96017,Q9UPY3,P42771,P21359,Q15645,O43683,O43684 7 +Thyroid adenoma 0.4560235898944684 0.7872483605500635 0.4311364924217051 1.0 0.8350598857288134 4 P20585 1 +Abnormal granulocyte count 0.4147697833223019 0.7832147206518502 0.4335010318784902 1.0 0.8375044959540863 78 P08708,Q07020,P62847,P61353,P49327,Q5F1R6,Q9P2D1,Q9NVI1,P62081,P42766,Q96BN8,P40763,P18074,P49917,P26639,O00203,P62854,P60866,P61313,O14617,P22681,P50851,P29144,P61254,P62899,Q6W2J9 26 +Delayed gross motor development 0.2334205190825263 0.7815456177011706 0.4344816575846308 1.0 0.8389551638501056 118 O60701,O95352,O43776,Q12873,P53618,Q9Y4A5,P57081,P26196,P42858,Q9Y5L0,Q14204,Q9Y296,P67870,P27635,Q7Z6Z7,P50570,Q9BV10,Q16512,Q9BPU6,Q15042,Q9UID3,Q7LBC6,Q8NCE2,Q01433 24 +Knee clonus 0.4452402267979601 0.7802971610684765 0.4352159834492979 1.0 0.8395892676831668 2 Q8N0X7 1 +Small for gestational age 0.3603086028836006 0.7778883094499671 0.4366348607624477 1.0 0.8406255146595694 87 P08708,Q07020,P62847,P61353,Q93008,A5YKK6,P38935,Q5F1R6,Q9UET6,Q14999,P62081,P42766,Q6PGP7,P46777,P18074,Q7Z6Z7,P50570,P62854,P60866,O00443,P61313,Q5SRE5,Q9BV10,Q15477,P61254,P62899 26 +External genital hypoplasia 0.2337293439407757 0.774670479028986 0.4385343992912713 1.0 0.8407976658065813 129 Q3SYG4,Q9UPP1,Q8IY37,O43933,Q9P2D1,Q9Y4A5,Q14999,O43709,P26196,Q14839,P27635,P18074,P78527,Q8IWS0,Q06124,P49917,O43505,Q07864,Q7Z6Z7,Q08AM6,O60826,Q15042,Q9BPU6 23 +Neonatal asphyxia 0.4602486419839531 0.7646994732761557 0.4444505199174469 1.0 0.8496685654285878 6 Q8NCE2,O94903 2 +Impaired tandem gait 0.4966807334539904 0.7637625676856771 0.4450087474399768 1.0 0.8503833272330626 17 Q06787,Q7Z6Z7,P26196,P42858,Q9Y296,Q9BPU6 6 +Joint swelling 0.4637494204100242 0.7623315730837326 0.445862134496104 1.0 0.8516612945882103 7 O96017,Q01968,O00170,P14174 4 +Long clavicles 0.4450746268656778 0.756259293920554 0.4494937486996682 1.0 0.8538830956818524 3 Q15813,Q14739 2 +Coarctation of aorta 0.5205760903663786 0.756054127220395 0.4496167438567569 1.0 0.8538830956818524 40 Q06124,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,Q14839,P61313,P21359,P61254,P62899,P46777,Q9Y4A5 16 +Nocturnal hypoventilation 0.4401671142942367 0.755440349030178 0.4499848109741715 1.0 0.8542304251126969 2 Q9Y281 1 +Biliary cirrhosis 0.4614825409281405 0.7513056725892764 0.4524687160998248 1.0 0.8575341772261676 7 Q9Y5L0 1 +Abnormal circulating igm level 0.4964372888758814 0.7500407667216238 0.4532301523573561 1.0 0.8581207050720202 18 O95394,P50851,P29144,Q00653,Q9Y5L0,P54132,P49327,Q96BN8,Q14790,Q9BV10 10 +Abnormality of urine calcium concentration 0.4820909023948688 0.7485729920164748 0.4541146155818885 1.0 0.8588891847803409 13 Q01968,Q9Y4X0,O00443 3 +Large earlobe 0.4604905334577358 0.7464918646007865 0.4553703441992156 1.0 0.8601381394493852 7 Q8IWS0,Q96N67 2 +Adrenal hypoplasia 0.4677062935013538 0.7447225564166132 0.456439460208035 1.0 0.8605063642454102 9 O60826,Q07864 2 +Neoplasm of fatty tissue 0.4639735935267209 0.7446853273944123 0.4564619712353173 1.0 0.8605063642454102 8 P27635 1 +Limb joint contracture 0.2283582462347061 0.7437483444819865 0.457028735992433 1.0 0.8609287730418388 106 P57081,O60231,P28482,O00443,Q15042,O43933,Q01968,Q9H4L7,P38935,Q13535,O14802,A1X283,Q92917,P27635,Q6W2J9,P18074,Q8IWS0,Q06210 18 +Absent or minimally ossified vertebral bodies 0.4452075246342281 0.7344953895520261 0.4626468690585938 1.0 0.8671241790232033 4 Q8NCM8,Q96EX3,Q14739 3 +Abnormal choroid plexus morphology 0.4494238812261413 0.7332623923418142 0.4633984077890496 1.0 0.867460980278204 5 P42771 1 +Simple ear 0.4519867447351227 0.7246585460960208 0.4686615322809451 1.0 0.8745694370598703 6 A1X283 1 +Incomitant strabismus 0.4875672391578929 0.7191819523207336 0.4720288178803706 1.0 0.8776577738339982 17 Q7Z6Z7,P26196,P42858,O00429,Q9Y296,Q9BPU6 6 +Aqueductal stenosis 0.45800475645428 0.7158853553802504 0.4740621418180812 1.0 0.880728417320503 8 Q9P2D1,P21359 2 +Congenital malformation of the great arteries 0.2279862879781762 0.7149041279420332 0.4746682861235176 1.0 0.8808529288756332 111 Q2VPK5,Q93008,O43933,P51532,A1X283,Q86Y56,Q9P2D1,Q9Y4A5,Q9Y6D5,Q9NVI1,O43709,Q14839,Q6PGP7,P46777,Q92908,Q9Y4X0,Q06124,P62854,Q08AM6,Q9BV10,Q15477,O15111,O60826,P57076,P28482,P46821,Q6W2J9 27 +Cortical dysplasia 0.5098408720188389 0.7145405969363171 0.4748929620883806 1.0 0.8808529288756332 30 O75182,O43505,O60524,Q9ULK4,Q96C86,P42345,Q13885,Q9NUQ7,Q9UBB6,P08243,Q2M389,Q6DN90,Q08J23,Q96F86,O00139,Q13620 16 +Bilateral microphthalmos 0.4490935167378598 0.710754608013532 0.4772363136073876 1.0 0.8845256859974996 6 Q08AM6,P18074 2 +Duplication of the distal phalanx of hand 0.4309161444344921 0.7105643027693505 0.4773542705361335 1.0 0.8845256859974996 2 Q8WVQ1 1 +Protruding tongue 0.470706263534549 0.709012574625339 0.4783166735576094 1.0 0.8857787294746096 12 O60826,O43933,P42356,P67870,O15111 5 +Abnormality of long bone morphology 0.2166455650299976 0.7036125151731978 0.4816741152943664 1.0 0.890923293445434 187 O15357,O00170,Q93008,O43933,P21359,Q01968,A1X283,Q13535,Q4G0J3,Q13126,Q5F1R6,Q9P2D1,Q9NVI1,Q14999,O43709,P26196,P42858,Q9Y296,Q06124,Q9Y4X0,P49917,Q07864,Q7Z6Z7,O00443,Q99575,Q08AM6,O14802,Q9BV10,Q13501,O96017,P26373,P28482,Q9HC07,P61254,Q6W2J9,Q9BTW9,Q9BPU6 37 +Abnormality of the lens 0.2117297720407761 0.7027690232113176 0.4821997047344939 1.0 0.8913943611202123 216 P08708,Q3SYG4,Q07020,P62847,P61353,Q93008,O43933,Q01968,P49327,P53618,P26358,Q13126,O43709,P62081,P42766,P18074,Q8IWS0,Q9Y4X0,P49917,O43505,P57678,P26639,P62854,Q8NHU6,O00443,P60866,P61313,Q96C23,Q08AM6,Q5SRE5,O14802,O60333,P35579,P40818,Q15042,P62899,Q6W2J9 37 +Oligodontia 0.4746399751593693 0.6976824355198261 0.485375815037675 1.0 0.894321293377185 14 Q9NW08,O00443,O14802,Q7Z6Z7 4 +Abnormality of vitamin d metabolism 0.4642086533987947 0.6939032267333072 0.4877428998958857 1.0 0.8978284107022031 11 P41252,Q01968,Q9NSD9,Q5F1R6,Q13043,P62913 6 +Colon cancer 0.4818194810703375 0.6914158528404393 0.4893042445170446 1.0 0.9000245402103257 17 O96017,P54277,P20585,P42771 4 +Bifid scrotum 0.4490239627674519 0.691380979892021 0.4893261536630169 1.0 0.9000245402103257 7 Q96EK5 1 +Generalized osteosclerosis 0.4310447761194138 0.688535849967865 0.4911154025177331 1.0 0.9021255899892 3 Q15392,P51798 2 +Gait disturbance 0.1964136354176829 0.6844019713686135 0.4937213715167154 1.0 0.9048616157356412 331 O75569,Q93008,P49327,O43776,P38935,P53618,Q13144,O75165,Q9P2D1,P52701,O43709,P07814,P26196,Q14839,P42858,P27708,Q14204,Q5TAQ9,Q9Y296,Q96IJ6,P27635,P26640,Q96F07,O00217,P18074,Q06210,Q9Y3I1,Q9H269,P04350,Q9BUK6,Q7Z6Z7,Q9NZJ4,P57678,P26639,P42345,P50570,P60866,Q00610,Q96N67,Q08AM6,O95248,Q69YN2,Q13315,Q13501,O60333,P46821,Q16512,O60231,Q99707,Q9C0E8,P35251,Q7Z460,Q9UID3,Q96C86,Q9BTW9,Q9BPU6,Q8NCE2,Q01433,P54277 59 +Sprengel anomaly 0.5042050174894279 0.6816858926206534 0.4954375897700516 1.0 0.9065662838592812 31 Q06124,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 12 +Abnormality of the curvature of the vertebral column 0.1974195275248781 0.6759285510769141 0.499086009455794 1.0 0.9103556272704844 325 P36507,Q9UPP1,P68400,Q9Y263,O00170,Q8IY37,Q93008,O95352,O15357,Q15436,Q13614,P21359,Q01968,P51532,O43776,P38935,Q13535,A1X283,P28340,P53618,Q4G0J3,Q9P2D1,Q12873,Q9Y4A5,Q9Y6D5,Q9H3P2,Q9NVI1,Q14999,O43709,P26196,O95163,P42858,Q14204,P40763,Q9Y296,P27635,P67870,P18074,Q8IWS0,Q06210,P04350,Q06124,Q9BUK6,P49917,O60524,Q07864,Q7Z6Z7,Q9NZJ4,P26639,P50570,O00443,Q99575,Q00610,O95248,O14802,Q9BV10,Q05639,O60826,P26373,P28482,P22681,Q06787,Q00796,P40818,P60953,Q9HC07,Q15042,Q15334,Q6W2J9,Q9Y223,P46821,Q9BTW9,Q9BPU6,Q8NCE2 74 +Long fingers 0.3680250441421784 0.6753051398762777 0.4994819190595265 1.0 0.9103556272704844 84 Q9UPP1,O15357,Q9Y263,O00170,Q93008,A5YKK6,P10589,O75909,O43776,P53618,P26196,Q14839,P27635,Q8IWS0,Q9Y4X0,Q96EK5,Q7Z6Z7,Q08AM6,Q9H4L7,O14802,Q9BV10,P28482,P46821,Q15334,Q9BPU6 25 +Oculogyric crisis 0.4600917063341421 0.6743313004991477 0.5001007085842508 1.0 0.9108417047829857 11 Q05639,P61457,Q00610,O00429,Q14204,P67870 6 +Prominent nasolabial fold 0.440813833470723 0.6713345627920548 0.5020074212305583 1.0 0.9127947316265532 6 Q93008 1 +Abnormality of the nasolabial region 0.440813833470723 0.6713345627920548 0.5020074212305583 1.0 0.9127947316265532 6 Q93008 1 +Aplasia hypoplasia of the ovary 0.4690133255369196 0.670849908272885 0.5023161498241926 1.0 0.9129962171548464 14 Q8IY37,Q3SYG4,Q9P2D1 3 +Triangular mouth 0.4405109686648895 0.6699035272681075 0.5029192910631197 1.0 0.9137324496550496 6 Q86XI2,P18074 2 +Nonimmune hydrops fetalis 0.5006331896761335 0.668457255267843 0.5038417583293553 1.0 0.9150480437690222 30 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899 11 +Congenital onset 0.2252069665760231 0.6667358421073597 0.504940880199835 1.0 0.9158468386499538 112 Q3SYG4,Q9Y263,A5YKK6,P42356,Q00535,P57081,Q9NRZ9,Q8N8R5,P41252,P27635,Q96EK5,O43505,Q07864,O00203,P50570,O14802,O15111,Q15042,P63241,Q99986,Q96C86,Q9BTW9 22 +Rickets 0.4437128698929484 0.6662140881506537 0.505274269318043 1.0 0.9158468386499538 7 Q01968,Q9NSD9 2 +Aplasia hypoplasia involving bones of the lower limbs 0.2865686192645787 0.6654984861444672 0.5057317114975077 1.0 0.9163159407454844 96 O15357,Q93008,Q13535,Q9H3P2,Q9P2D1,Q9Y4A5,P26196,Q14839,P42858,Q9Y296,Q8IWS0,Q9Y4X0,P49917,Q7Z6Z7,O00443,Q99575,Q08AM6,O14802,Q9BV10,O15111,Q13555,Q9BPU6 22 +Abnormal neutrophil count 0.4371684206837727 0.664666471617048 0.5062638432857494 1.0 0.91665246606616 70 P08708,Q07020,P62847,P61353,P49327,Q5F1R6,Q9NVI1,P62081,P42766,Q96BN8,P40763,P18074,P26639,O00203,P62854,P60866,P61313,O14617,P22681,P50851,P29144,P61254,P62899,Q6W2J9 24 +Abnormal lower limb bone morphology 0.2181777666683728 0.6628427861011076 0.5074312478090348 1.0 0.917953076918854 175 Q3SYG4,O15357,Q9Y263,Q93008,O43933,P21359,A1X283,Q13535,Q9H3P2,Q5F1R6,Q9P2D1,Q9Y4A5,Q9NVI1,Q14999,P26196,Q14839,P42858,Q9Y296,P18074,Q8IWS0,Q9Y4X0,P49917,O43505,Q7Z6Z7,O00443,Q99575,Q08AM6,Q5SRE5,O14802,Q9BV10,O15111,O96017,P26373,P28482,Q13555,Q9BPU6 36 +Multiple lentigines 0.4386745350649272 0.6612436453506289 0.5084560754382228 1.0 0.9191014476867552 6 Q06124,P28482 2 +Abnormal blood sodium concentration 0.4638118121337738 0.6608736380377401 0.508693353367224 1.0 0.9191548919244044 13 O95163,P08397,Q01968,P50336,Q9UNF1,Q9BV10 6 +Camptodactyly of toe 0.441746107778963 0.6569570800294681 0.5112085142467091 1.0 0.9215337538960802 7 Q6W2J9,Q8IWS0 2 +Premature loss of teeth 0.4593537013791866 0.6550501335944275 0.5124354765377277 1.0 0.923321500752308 12 Q08AM6,O14802 2 +Disturbance of facial expression 0.4410517905577273 0.6536974758037228 0.5133067298253275 1.0 0.923321500752308 7 Q8NCE2,O94903 2 +Breathing dysregulation 0.428274125329972 0.6536484333659254 0.5133383327756953 1.0 0.923321500752308 4 O95163 1 +Increased circulating prolactin concentration 0.4370378134750171 0.6535509077186253 0.5134011813201105 1.0 0.923321500752308 6 Q9BUK6,O14802 2 +Abnormal waist to hip ratio 0.4403743021963686 0.6505211398856194 0.5153556510781396 1.0 0.9248673754948972 7 P17096 1 +Abnormal conjugate eye movement 0.195756818891006 0.6483100758025263 0.5167844184558406 1.0 0.9265163320391732 328 Q9NPL8,P08708,Q3SYG4,Q07020,P62847,Q8IY37,Q93008,P61353,O95352,O43933,P10589,P21359,Q01968,Q7KZN9,P51532,Q12873,Q13535,Q4G0J3,Q9H3P2,Q9P2D1,Q9H1B7,Q9NVI1,Q8IUX1,Q9NR45,O43709,P62081,P26196,P42766,P42858,Q6XZF7,Q9Y296,Q96IJ6,P27635,O00217,P18074,Q06210,Q06124,Q9Y4X0,P49917,Q7Z6Z7,P26639,P42345,O00203,P62854,P60866,P61313,O95248,O14802,Q13315,Q9BV10,Q13501,Q16512,P22681,P61254,P62899,Q15334,Q6W2J9,Q9UID3,Q9BTW9,Q9BPU6 60 +Acute myeloid leukemia 0.4995555300000198 0.6446294430210557 0.5191673499089917 1.0 0.9283038354552442 36 O96017,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P42771,P62899,Q5F1R6 14 +Arteriovenous malformation 0.4306882219069123 0.6440914203336248 0.519516153569503 1.0 0.9283038354552442 5 Q9NVI1,Q92990 2 +Aplasia hypoplasia of the gallbladder 0.4261980487184036 0.6439038247530647 0.5196378014512129 1.0 0.9283038354552442 4 A5YKK6 1 +Severe combined immunodeficiency 0.442786396047736 0.6437659780863502 0.5197271986111291 1.0 0.9283038354552442 8 P49917,P78527,Q9P2D1 3 +Redundant neck skin 0.4465048969939353 0.6437132643583025 0.519761386936187 1.0 0.9283038354552442 9 Q08AM6,A1X283 2 +Interrupted aortic arch 0.4250981904212307 0.6387575016217067 0.5229806991072248 1.0 0.9318308091856424 4 Q9P2D1 1 +Hereditary nonpolyposis colorectal carcinoma 0.445227775520328 0.6377548037358879 0.5236333045317845 1.0 0.9324265565941888 9 O96017,O14965,P52701,Q9Y620 4 +Atrophy degeneration affecting the cerebrum 0.2053980675805319 0.6376226978057538 0.5237193167430183 1.0 0.9324265565941888 243 P00374,Q9Y263,O95352,P26358,O75165,Q9Y4A5,Q9H1B7,Q9NR45,Q14746,Q9ULK4,O43709,P07814,P26196,P42858,Q14204,Q9Y296,Q96F07,P67870,P26640,Q96F86,P18074,Q9H269,O60524,Q7Z6Z7,Q9NZJ4,P26639,Q9UBB6,Q00610,Q96N67,O14802,Q92917,Q13501,P47897,Q05639,O14617,Q06787,Q04637,P60953,Q99707,Q9NW08,Q15042,Q96C86,Q9BTW9,Q9BPU6,Q2M389,Q01433 46 +Abnormal myelination 0.2067401493396271 0.6298250162315493 0.5288090764636595 1.0 0.9383622155096982 226 P00374,Q9NPL8,Q9Y263,Q8IY37,O60701,O43933,P10589,Q13614,Q7KZN9,O43776,Q13144,P26358,Q9Y4A5,Q8IUX1,P07814,Q8N8R5,P26196,O95163,Q5TAQ9,Q96F07,O00217,P78527,P18074,P04350,O94903,P57678,Q9NZJ4,P26639,P50570,Q00610,O95248,Q5SRE5,O14802,Q9BV10,O60333,Q16512,O14617,O60231,Q9NW08,Q15042,P35251,Q9BTW9 42 +Muscle hypertrophy of the lower extremities 0.4397213742517225 0.6294934622853727 0.5290260474835542 1.0 0.9383622155096982 8 O60231,Q8NCE2 2 +Primitive neuroectodermal tumor 0.4735644827852706 0.6282118603948469 0.5298651616927512 1.0 0.9393287272339452 19 Q06124,O96017,P52701,P42771,P21359,P54277,O60333 7 +Neuronal loss in central nervous system 0.4598847784780192 0.6279455648801612 0.5300396004747365 1.0 0.9393287272339452 14 Q08AM6,P42858,P26358 3 +Long foot 0.4492371078837114 0.6234733451054869 0.5329735129805204 1.0 0.9423560043614952 11 O00170,O14802,P21359 3 +Thick upper lip vermilion 0.4414516875060312 0.6202305539066745 0.5351060084910939 1.0 0.944174452418897 9 P62081,Q08J23,Q9UID3 3 +Abnormality of the columella 0.4579911225757418 0.6191493029475149 0.5358180062465672 1.0 0.9441793800846952 14 Q9BTW9,O00443 2 +Decreased circulating total igm 0.4409411242738572 0.6178720402868558 0.5366596908808954 1.0 0.9441793800846952 9 P49327,P50851,Q00653,P54132 4 +Ovarian neoplasm 0.4780297376997628 0.6178485880871111 0.5366751515181156 1.0 0.9441793800846952 22 O96017,Q8IY37,P20585,P42771,Q01844,P54277 6 +Prominent metopic ridge 0.4605038130442775 0.6169872665321228 0.537243124631118 1.0 0.944475051037861 15 P18074,Q5SRE5,P28482,P46821 4 +Abnormality of reproductive system physiology 0.2227761411559007 0.6157209960665251 0.5380786774932922 1.0 0.945172635691159 147 Q3SYG4,O00170,Q8IY37,O43933,P31751,P54132,Q01968,P48651,P49327,Q13144,P28340,Q86Y56,Q9P2D1,Q9NVI1,Q14999,P17612,O43709,P42858,P49770,P40763,Q96RD7,Q9UBS4,Q92620,P18074,Q8IWS0,Q06124,P49917,Q9BUK6,Q07864,Q9NZJ4,O00429,O14802,Q13315,Q12830,P57076,Q06787,P22681,Q6NXR4,P35579,Q9NW08,P40818,Q15042,Q6W2J9,Q6P2Q9 44 +Upslanted palpebral fissure 0.2964458665668589 0.6131142216057585 0.5398008172984097 1.0 0.9466400938797028 94 O60826,Q9UPP1,Q7Z6Z7,Q93008,O43933,P10589,Q08AM6,Q01968,O43776,P53618,O14802,Q00534,Q9BTW9,Q9Y4A5,P42695 15 +Abnormality of renal excretion 0.4282167075770497 0.6125246414328811 0.5401906998416974 1.0 0.9466400938797028 6 Q9UNF1,P07741,O43772 3 +Language impairment 0.1992108038743002 0.610594146471334 0.54146829883605 1.0 0.9475917544499276 300 O75569,Q3SYG4,P68400,Q9UPP1,Q9Y263,Q93008,A5YKK6,O95352,O43933,P10589,P51532,P42356,P21359,O43776,Q12873,P53618,Q86Y56,Q9Y4A5,P57081,Q9UET6,Q9ULK4,Q9UPN3,Q15021,P26196,P42858,P41252,Q9Y296,Q96F07,P27635,Q96F86,P18074,Q14353,P04350,Q9Y4X0,Q969U7,Q9BUK6,P49917,O60524,Q7Z6Z7,P57678,Q9UBB6,Q00610,Q08AM6,Q69YN2,Q9BV10,Q13501,Q16512,Q05639,P57076,Q06787,P28482,P22681,P60953,Q8NC96,Q9C0E8,Q7LBC6,P35251,Q9Y223,P46821,Q96C86,Q9BTW9,Q9BPU6,Q2M389 63 +Respiratory arrest 0.4355294374936331 0.610123543030487 0.5417799721192038 1.0 0.9475917544499276 8 O43772 1 +Digenic inheritance 0.4142227946218092 0.6094853174685227 0.54220280189695 1.0 0.9475917544499276 3 A6NHR9 1 +Abnormality of hindbrain morphology 0.2000665899460997 0.6075835802956382 0.5434636936796955 1.0 0.9480489546826713 290 P00374,Q9Y263,Q8IY37,Q93008,O95352,P51532,P42356,Q00535,Q13535,P26358,Q9H3P2,Q9P2D1,Q9Y4A5,Q9H1B7,Q9NVI1,P57081,Q9UPN3,O43709,P07814,Q14839,P42858,Q14204,Q9Y296,Q96F07,P27635,P26640,P78527,P18074,P04350,Q9BUK6,O43505,P26639,Q9NZJ4,Q96N67,Q08AM6,O14802,Q69YN2,Q92917,Q9BV10,Q13501,O60826,Q9NW08,Q9C0E8,Q15042,Q15334,P35251,Q99986,Q7Z460,Q6W2J9,Q9UID3,Q9BTW9,Q9BPU6 52 +Regional abnormality of skin 0.2232916271559936 0.6030924849840743 0.5464471655057759 1.0 0.9510962929324676 134 Q9Y263,O00170,O43933,Q13535,Q9P2D1,O43709,P26196,P42858,Q9Y296,Q96IJ6,P27635,P18074,Q06124,Q7Z6Z7,P42345,Q08AM6,Q9H4L7,Q5SRE5,Q92917,O15111,P46821,P62266,Q9BPU6,Q15042,Q9UID3,Q6W2J9 26 +Thin eyebrow 0.4574542756089296 0.602898435560751 0.5465762567882011 1.0 0.9510962929324676 15 Q96EK5,O43933,O75909,O14802,P46778 5 +Male reproductive system neoplasm 0.454017863012833 0.6008159840461824 0.547962556741795 1.0 0.9520793853229794 14 O96017,Q01844,P42771 3 +Aplastic anemia 0.4368085972230267 0.598881153225071 0.5492521402270127 1.0 0.9539533595132568 9 O76094,P98170,Q9H1A4,Q5F1R6 4 +Wide intermamillary distance 0.4773016124035205 0.5964244249032652 0.550891727540173 1.0 0.955151476264134 24 Q06124,Q9Y4X0,Q96EK5,Q96KP1,P22681,Q9BZH6,Q92974,P21359,Q5SRE5,Q15555,Q9P2D1 11 +Centrally nucleated skeletal muscle fibers 0.4283648546290669 0.5949543898547421 0.5518739591897686 1.0 0.9552700089089692 7 Q8NCE2,Q9Y5L0 2 +Ptosis 0.2043479918554235 0.5934355934483364 0.5528896743181828 1.0 0.95620516746371 235 P36507,Q9NPL8,P08708,P68400,Q07020,P62847,O00170,Q5TBB1,O60701,Q8IY37,P61353,O43933,O95352,P51532,P21359,Q7KZN9,Q9H3P2,Q9P2D1,Q9Y3Z3,Q9NVI1,Q8IUX1,P62081,P26196,P42766,P42858,Q14839,P40763,P46777,Q9Y296,Q96F07,P26640,O00217,Q06210,Q8IWS0,Q06124,P49917,Q96EK5,Q7Z6Z7,P50570,P62854,P60866,P61313,Q00610,Q13501,O60333,Q05639,P28482,P22681,P60953,Q8NC96,Q92974,P62899,Q15042,P61254,Q6W2J9,Q9BPU6,Q8NCE2 57 +Urticaria 0.4353253869338157 0.5921091352729374 0.553777510019529 1.0 0.9564117011306954 9 P49327,P18074,Q9Y5L0 3 +Neoplasm of the skeletal system 0.4870252968586194 0.58692095613732 0.5572567946813762 1.0 0.9609815304168928 43 Q06124,O96017,P52701,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61313,P42771,P62899,Q13126,Q13501,P54277 17 +Neoplasm of the genitourinary tract 0.4127408242816084 0.5833226735186098 0.5596761018488781 1.0 0.9636822851790764 73 P08708,Q07020,P62847,P61353,Q8IY37,P20585,P21359,P42771,P28340,O14965,P52701,P62081,P42766,Q01844,Q07864,P62854,P60866,P61313,O60333,O96017,P62899,P54277 22 +Thickened helices 0.4294634688020203 0.582417856580013 0.5602852566334886 1.0 0.9636822851790764 8 Q06124,P22681 2 +Cleft lip 0.465701911480271 0.5811491425243792 0.5611399405349333 1.0 0.9647925999581244 57 P08708,Q9UPP1,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P29372,P61313,P61254,P62899,Q6W2J9,Q9H3P2,Q9P2D1,Q9Y4A5,O15111 18 +Aplasia hypoplasia of the uvula 0.4169653524492053 0.5808139958784718 0.561365821247042 1.0 0.9648213611820436 5 Q01082,Q9BXW9,Q9NVI1,P38398 4 +Focal emotional seizure 0.431997540726058 0.5770024440838766 0.5639378044681964 1.0 0.9669002128911413 9 Q05639,Q14204,Q00610,P67870 4 +Abnormal uvea morphology 0.2250263493800281 0.5763073238350529 0.564407473405039 1.0 0.9669002128911413 103 O43933,P21359,Q01968,P49327,Q9H3P2,Q9P2D1,Q9NVI1,P52701,O43709,P14174,P26196,Q96IJ6,Q96EK5,O43505,O00203,Q9UDY8,O60333,O60826,O14617,O60231,P28482,P50851,Q6W2J9 23 +Ventricular fibrillation 0.4159306171520667 0.5761226082704594 0.5645323110379326 1.0 0.9669002128911413 5 Q99996 1 +Herpes simplex encephalitis 0.4016711429424009 0.5734212009297149 0.5663595388236955 1.0 0.9683530587819694 2 Q9UHD2 1 +Esophageal carcinoma 0.4016711429423978 0.5734212009297002 0.5663595388237055 1.0 0.9683530587819694 2 Q8N9N2 1 +Primary gonadal insufficiency 0.430879617066642 0.5719554322577896 0.5673521685471938 1.0 0.9691756901410143 9 Q8IY37,Q13144 2 +Abnormality of upper limb joint 0.2205319705515489 0.566325489353395 0.5711725360510724 1.0 0.9708249479747962 122 O43933,P21359,Q01968,P38935,Q13535,A1X283,P57081,Q14999,O43709,P27635,P18074,Q06124,O00443,Q99575,Q9H4L7,O14802,Q92917,Q9BV10,O60231,P28482,P22681,Q15042,Q6W2J9 23 +Respiratory paralysis 0.4044756134799895 0.56495827722906 0.572102143337297 1.0 0.9709739467310344 3 P50336 1 +Porphyrinuria 0.4044756134799895 0.56495827722906 0.572102143337297 1.0 0.9709739467310344 3 P50336 1 +Elevated urinary dicarboxylic acid level 0.4044756134799895 0.56495827722906 0.572102143337297 1.0 0.9709739467310344 3 P50336 1 +Paranoia 0.4044756134799895 0.56495827722906 0.572102143337297 1.0 0.9709739467310344 3 P50336 1 +Absence of subcutaneous fat 0.416184465255133 0.5578557763438443 0.5769428719172536 1.0 0.975711863003078 6 P18074,O14802 2 +Abnormal bronchus morphology 0.468836107940697 0.5572461394773797 0.5773592695203109 1.0 0.975711863003078 24 P57076,O95394,Q13432,P50851,Q00653,P29144,Q03518,P54132,Q13315,Q86Y56,Q86TI2 11 +Phalangeal dislocation 0.3980901223515364 0.557218765767964 0.577377969785156 1.0 0.975711863003078 2 Q8WVQ1 1 +Atrophy degeneration affecting the central nervous system 0.1966797858040786 0.5552430899424625 0.5787283992209189 1.0 0.9768291641442002 302 P00374,O75880,Q9Y263,Q93008,O95352,O43776,P38935,P53618,P26358,O75165,Q9Y4A5,Q14746,O43709,P07814,P26196,P27708,P42858,Q14204,Q9Y296,Q96F07,P67870,P26640,Q96F86,P78527,P18074,Q9H269,O60524,O94903,Q7Z6Z7,Q9NZJ4,P26639,Q00610,Q96N67,Q08AM6,O95248,O14802,Q13501,O14617,Q9NW08,Q99707,Q15042,Q99986,Q96C86,Q9BTW9,Q9BPU6,Q2M389,Q01433 47 +Abnormal soft palate morphology 0.408469863115081 0.5540021514616593 0.5795773733290366 1.0 0.9771894821516248 73 P08708,Q07020,Q15436,P62847,P61353,Q93008,P48651,Q9P2D1,Q9NVI1,Q15058,Q9BUF5,P62081,P42766,Q6PGP7,P46777,P62244,Q9Y4X0,O43505,P62854,P60866,P61313,O14802,P62266,P61254,P62899,Q6W2J9,Q13618 27 +Abnormally large globe 0.4302715265601852 0.5530527097021452 0.5802273175227728 1.0 0.9775707142923852 10 A1X283,Q13535 2 +Deeply set eye 0.4036569892262872 0.5507639168285536 0.5817955225202835 1.0 0.9782584970775846 74 O60701,P21359,Q01968,A1X283,Q4G0J3,Q9Y4A5,Q13045,P40763,P35573,P18074,P78527,Q8IWS0,Q7Z6Z7,O00429,O14802,Q92917,Q16512,Q12830,Q05639,Q14738,Q06787,P28482,Q6NXR4,Q15042,P63241,Q9NSD9,Q96C86,Q9BTW9,Q9BPU6 29 +Myelodysplasia 0.473117227273835 0.5506054278274413 0.5819041872252146 1.0 0.9782584970775846 50 P08708,Q07020,P62847,P61353,P21359,P42771,Q5F1R6,Q9NVI1,P62081,O76094,P42766,Q06124,P49917,P62854,P60866,P61313,O96017,P61254,P62899 19 +Abnormal pupil morphology 0.43608478492997 0.5484362424587544 0.5833923965879981 1.0 0.9782584970775846 12 Q01968,P26196,O95163,Q96IJ6 4 +Low levels of vitamin d 0.428533690212191 0.5453211256814676 0.5855326770054401 1.0 0.9807778645701144 10 Q01968,Q9NSD9,Q5F1R6,Q13043,P62913 5 +Short ribs 0.4380908914264418 0.5429415394023075 0.5871700541639937 1.0 0.9814358309361072 13 Q08AM6,Q14999,Q9BV10 3 +Stomach cancer 0.431193427615619 0.5416564255538798 0.588055212993243 1.0 0.9817946788048606 11 O96017,P60866,P20585,P42771,P54132,Q15645,O43683,O43684 8 +Aplasia hypoplasia of the hallux 0.460736893449279 0.5382524571872683 0.5904027690792253 1.0 0.9837220831878416 22 Q7Z6Z7,P26196,P42858,Q08AM6,Q9Y296,Q9BPU6 6 +Abnormality of the kidney 0.1930585896088552 0.5372544252293378 0.5910918815765107 1.0 0.9840231626895566 346 Q9NPL8,P08708,Q3SYG4,Q2VPK5,Q07020,P62847,O00170,Q8IY37,Q93008,P61353,O43772,O43933,P42771,P20585,P21359,Q01968,P49327,P51532,Q5F1R6,Q9P2R3,Q9P2D1,Q9H3P2,Q9Y4A5,Q9Y5K6,P42695,Q9NVI1,Q8IUX1,P52701,P57081,O14965,O43709,P06737,P62081,P26196,P42766,Q14839,P27708,P41252,O95163,Q6PGP7,P40763,Q9UBS4,Q00534,O00217,Q06124,Q9Y4X0,P49917,O43505,Q07864,P53621,P57678,P62854,P60866,O00443,P61313,Q08AM6,O14802,Q92917,Q15477,O15111,O96017,O60333,O60826,O60231,P28482,P35579,P40818,Q15042,P62899,P61254,Q6W2J9 71 +Abnormality of the female genitalia 0.2181746947847718 0.5372477290370176 0.5910965063543814 1.0 0.9840231626895566 144 Q3SYG4,O00170,Q8IY37,O43933,P20585,P42771,P31751,P49327,Q13144,Q13535,P28340,Q9P2D1,P52701,O14965,O43709,Q01844,Q06124,P49917,Q07864,P60866,Q08AM6,Q13315,O96017,P31939,Q15042,Q6W2J9,P54277 27 +Flared metaphysis 0.4331366578652488 0.5353692972230184 0.5923945164800852 1.0 0.9854727387387788 12 Q08AM6,Q9NR45,A1X283 3 +Porencephalic cyst 0.4104265191574693 0.5322782887221443 0.5945332671406489 1.0 0.987375305695264 6 Q5TBB1 1 +Congenital nystagmus 0.4498176248119734 0.5311167773262587 0.5953378587549267 1.0 0.9882308537015032 18 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Broad foot 0.4212572842956656 0.5291222866134005 0.5967206220780383 1.0 0.9898138186429308 9 P27635,Q8IWS0 2 +Cleft soft palate 0.4430888669642598 0.5255133716100621 0.5992263602817021 1.0 0.9922514331219808 62 Q9Y4X0,O43505,P08708,Q07020,P62847,P62081,P61353,Q93008,P60866,P42766,P62854,P61313,P62266,P62899,Q6PGP7,O14802,Q6W2J9 17 +Pes cavus 0.2135602278181503 0.5186018807709775 0.6040383972585623 1.0 0.9972903101480846 106 Q96IJ6,Q9BUK6,O00764,Q7Z6Z7,Q9NZJ4,Q93008,O95352,P26196,P42858,P21359,O43776,Q5TAQ9,Q14204,Q9Y296,Q9P2D1,Q9BPU6,P46821,O60333 18 +Sclerocornea 0.4223427191260784 0.5180822571777682 0.6044008789907802 1.0 0.997531754842386 10 Q08AM6 1 +Abnormal ossification involving the femoral head and neck 0.3983278590623994 0.5174011218449852 0.6048761767255137 1.0 0.9979591570939896 4 Q9NUQ7,Q14739,O75369 3 +Hypokalemia 0.4184077152207065 0.5166570520078915 0.605395581758706 1.0 0.9984589984458028 9 O00170,P40818,Q01968,Q99996 4 +Metopic synostosis 0.3931343283582155 0.5145188112825891 0.6068893119115586 1.0 0.999570613496268 3 P18583,P61978 2 +Congenital hypothyroidism 0.401593763332712 0.5124084657850226 0.608365167281705 1.0 0.9997821577023532 5 Q9Y263 1 +Hyperpigmentation of the skin 0.2933942721967262 0.5110879793147249 0.6092894527366721 1.0 1.0 93 O00170,P21359,P53618,A1X283,P52701,P26196,P42858,Q9Y5L0,Q6PGP7,Q96IJ6,Q9Y296,P18074,Q06124,Q7Z6Z7,P42345,Q9H4L7,Q13315,Q15477,O60333,P28482,P22681,Q9BPU6 22 +Abnormal cerebral ventricle morphology 0.1994532370245276 0.5075220006346048 0.6117886035745161 1.0 1.0 243 P36507,Q9NPL8,Q9Y263,Q5TBB1,O60701,Q8IY37,Q93008,O43933,P51532,P42771,P21359,Q9BSJ2,Q12873,Q01968,P26358,Q86Y56,Q9P2D1,P42695,Q9NVI1,Q9NR45,Q9NRZ9,P57081,Q14839,P42858,P08243,Q14204,Q00534,Q96F07,P67870,P18074,P49917,Q96EK5,O43505,O94903,Q7Z6Z7,P26639,P42345,Q00610,Q08AM6,Q5SRE5,O14802,Q9BV10,P47897,Q05639,O60826,P57076,O96017,O75182,P60953,Q15042,Q7Z460,Q6W2J9,Q9UID3,Q9BTW9,Q9BPU6,Q01433 56 +Abnormal fingertip morphology 0.4650625675682132 0.5053061377534187 0.6133438325419778 1.0 1.0 29 O14646,P62266,Q7Z6Z7,P50851,P42858,Q6W2J9,Q9Y296,Q9BPU6,P46821 9 +Selective tooth agenesis 0.4078137675382383 0.5035613987888319 0.6145696240857104 1.0 1.0 7 Q13535 1 +Exercise induced myoglobinuria 0.3994948452190853 0.5032954214160972 0.6147565850416639 1.0 1.0 5 P08237,P46020,P00338 3 +Abnormality of the bladder 0.216503594816745 0.5016245626421894 0.6159316380601947 1.0 1.0 125 O00170,Q93008,P53618,P38935,P26358,O75165,Q9P2D1,Q9Y4A5,P42695,O43709,P26196,Q14839,Q00534,Q9Y3I1,Q9NZJ4,O95248,O14802,Q13501,Q9BTW9,Q8NCE2 20 +Abnormal immune system morphology 0.2126645329086652 0.5010462104866661 0.6163386013566867 1.0 1.0 165 P08708,Q07020,P62847,P61353,P42771,P21359,P49327,Q5F1R6,Q9P2D1,Q9NVI1,Q9NRZ9,P62081,P17812,P42766,Q96BN8,P40763,Q6PGP7,P18074,Q06124,P49917,P26639,O00203,P62854,P60866,P61313,Q13315,Q9BV10,Q15477,O96017,O14617,P22681,P35579,P50851,P29144,P61254,P62899,Q6W2J9 37 +Lymphopenia 0.4642356028322432 0.4914121586431189 0.6231349664221302 1.0 1.0 31 Q9NRZ9,O95394,P31146,Q6NXR4,Q13432,P50851,P17812,P29144,Q00653,P49327,Q6PGP7,Q13315,Q9BV10,Q9P2D1,Q96Q11,Q15477 16 +Short thumb 0.467010162754794 0.4904681138071279 0.6238026879226832 1.0 1.0 44 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q9H3P2,Q9P2D1,Q6W2J9,Q9NVI1 15 +Pallor 0.4550772904998389 0.489668462690743 0.6243685218902031 1.0 1.0 54 P00374,Q9BUK6,P08708,Q07020,P62847,O00170,P61353,P62081,P62854,P42766,P60866,Q9Y5L0,P21359,P61313,P61254,P62899,O60333,Q9NVI1 18 +Recurrent respiratory infections 0.2157531869906638 0.4894955326260256 0.6244909165380976 1.0 1.0 126 Q9NPL8,O15357,Q93008,P51532,Q01968,Q9H3P2,Q86Y56,Q9NRZ9,O43709,P14174,O95163,P40763,P78527,P18074,Q07864,P26639,O00203,O14802,Q13315,Q9BV10,Q9UDY8,O60826,O14617,P28482,P50851,P29144,Q9UID3,Q9BTW9 28 +Focal white matter lesions 0.3999019672680924 0.48660851188452 0.6265357903454221 1.0 1.0 6 O00443 1 +Striae distensae 0.4110963619726072 0.4851646438262491 0.6275595598024366 1.0 1.0 9 P17612,O00170,P40818,P53618,Q15334 5 +Cubitus valgus 0.4410943670176674 0.4820725696341612 0.6297543950574807 1.0 1.0 19 Q06124,P36507,P28482,P22681,O43933,Q99575,P21359,Q6W2J9 8 +Anemia of inadequate production 0.4198610086910549 0.4806552649295728 0.6307615303383582 1.0 1.0 67 P00374,P08708,Q07020,P62847,P62081,P61353,Q8N8R5,P62854,P42766,P60866,P61313,Q99707,P49327,P61254,P62899,Q5F1R6,Q9UER7,Q9NVI1 18 +Abnormal levels of alpha fetoprotein 0.4061633429385466 0.4800346740788517 0.6312027377117713 1.0 1.0 8 Q13315 1 +Aplasia hypoplasia of the thumb 0.4578023282630834 0.4724551674609445 0.6366019349980756 1.0 1.0 50 P49917,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,Q08AM6,Q9H3P2,Q9P2D1,Q6W2J9,Q9NVI1 17 +Cerebral hypoplasia 0.4336361121556742 0.4724305177190576 0.6366195257614655 1.0 1.0 17 P42695,Q00534 2 +Combined immunodeficiency 0.4115254668712822 0.4717052687003426 0.6371371759241018 1.0 1.0 10 P49917,O95394,Q00653,P11586,Q9P2D1,P78527 6 +Anterior pituitary dysgenesis 0.3830944104082921 0.4712448558492272 0.6374658898553722 1.0 1.0 3 Q92908 1 +Abnormally folded helix 0.4428141418184879 0.4692698700109678 0.6388767488781633 1.0 1.0 21 Q9Y4X0,P62266,O43776,Q9UID3,Q9P2D1,Q6W2J9,O15111 7 +Mixed hearing impairment 0.4066656492453736 0.4664404242897003 0.6409002818946052 1.0 1.0 9 Q9Y4X0 1 +Spinal canal stenosis 0.3950895888995291 0.4662263067435251 0.6410535211387578 1.0 1.0 6 Q8IWS0 1 +Rectal prolapse 0.4101117065199237 0.4657653680637992 0.6413834567765868 1.0 1.0 10 Q08J23,P49917,Q6W2J9,O43709 4 +Woolly hair 0.3949499725451294 0.4656399085718862 0.6414732717861809 1.0 1.0 6 Q15477 1 +Abnormality of the calf musculature 0.4261242413892476 0.4646940593758345 0.6421505631808486 1.0 1.0 15 O60231,Q8NCE2,Q9NZJ4,Q96IJ6 4 +Spastic hyperactive bladder 0.3939227238902815 0.4613341025931147 0.644558921619963 1.0 1.0 6 O75165,Q04637 2 +Cafe au lait spot 0.4565044318479363 0.460216606044989 0.6453607526343026 1.0 1.0 49 Q06124,P52701,P28482,Q7Z6Z7,P42345,P22681,P26196,P42858,P21359,P53618,A1X283,Q6PGP7,Q13315,Q9Y296,Q9BPU6,Q15477,O60333 17 +Tracheomalacia 0.4122516004797443 0.4601221373761308 0.6454285551266654 1.0 1.0 11 P46777,Q93008,Q9Y4A5 3 +Anotia 0.3847183545645437 0.4590714818403458 0.6461828350615382 1.0 1.0 4 O15111 1 +Abnormality of the intrahepatic bile duct 0.3890619333836352 0.4588902779958548 0.6463129605827544 1.0 1.0 5 Q9Y5L0 1 +Abnormal joint morphology 0.1942873181014197 0.4588580712116225 0.646336089947563 1.0 1.0 278 O15357,O00170,Q93008,O43933,P21359,Q01968,P49327,P38935,Q13535,A1X283,Q5F1R6,Q9Y6D5,Q9NVI1,Q9NR45,P57081,Q14999,O43709,P14174,Q8N8R5,O95163,P42858,Q14839,Q96BN8,Q9UBS4,P27635,P18074,Q8IWS0,Q06210,Q06124,P53621,P57678,P26639,O00203,O00443,Q99575,Q08AM6,Q9H4L7,O14802,Q92917,Q9BV10,O15111,O96017,O60231,P26373,P28482,P22681,P50851,Q15042,P61254,P63241,Q6W2J9,P46821,P08237,Q9BTW9,Q9BPU6 55 +Chronic neutropenia 0.3971133157578762 0.4581312264999989 0.6468581657598245 1.0 1.0 7 P50851 1 +Abnormal pancreas morphology 0.430185405423534 0.4579031334313582 0.6470220356103702 1.0 1.0 17 P40763,A5YKK6,Q9UBS4,Q5F1R6 4 +Male hypogonadism 0.4034946221791514 0.453214605461688 0.6503942163782135 1.0 1.0 9 O00170,Q9P2D1,P09884,Q9BZH6 4 +Abnormality of the gastric mucosa 0.4232454805548226 0.4526716587930566 0.6507851903525941 1.0 1.0 15 P49327,P50851,O43709,Q15477 4 +Aplasia hypoplasia of the earlobes 0.4136856227746435 0.4520635236356093 0.6512232204274191 1.0 1.0 12 Q13535,O14802 2 +Abnormal incisor morphology 0.4333353309779831 0.4492895968536304 0.6532227613950781 1.0 1.0 19 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Relative macrocephaly 0.4569353227833926 0.4476904595946622 0.6543766079372628 1.0 1.0 34 Q07864,Q7Z6Z7,Q93008,P42858,Q99575,P21359,O14802,Q9Y296,Q9BPU6 9 +Curly hair 0.4122536073271577 0.4461455754100276 0.6554920933486676 1.0 1.0 12 Q6PGP7,Q93008,Q9BPU6 3 +Generalized tonic seizure 0.4295332229657779 0.4440925482683583 0.6569756737782302 1.0 1.0 18 Q14746,P27635,Q00610,Q96N67,Q14204,P67870,Q9BTW9 7 +Gaze evoked nystagmus 0.4083666172396011 0.444029300745101 0.6570213998925374 1.0 1.0 11 Q9NZJ4 1 +Tongue thrusting 0.376417910447771 0.4432560838269667 0.6575805169385656 1.0 1.0 3 Q14683,Q05086 2 +Hypocholesterolemia 0.4007629516282482 0.4419420388491651 0.6585311489637871 1.0 1.0 9 Q9Y6B6 1 +Synostosis involving digits 0.3758576062749512 0.4409374883174077 0.6592582529990454 1.0 1.0 3 P48651 1 +Irregular menstruation 0.392456562064617 0.4388785600436293 0.6607495326268675 1.0 1.0 7 O00170,Q3SYG4 2 +Abnormal internal genitalia 0.2120980427289789 0.4378349049683206 0.6615059661267941 1.0 1.0 126 Q3SYG4,O00170,Q8IY37,P20585,P42771,P31751,P49327,Q13144,P28340,Q9P2D1,P52701,O14965,O43709,Q01844,P18074,Q8IWS0,Q06124,Q07864,P26639,P60866,Q13315,O96017,Q6W2J9,P54277 24 +Abnormal renal collecting system morphology 0.3918505732943065 0.4363974506669522 0.6625483882855963 1.0 1.0 7 Q9Y4R8,Q9BXW9,P28482,P41252 4 +Gynecomastia 0.4370541098766637 0.435883063045365 0.6629215741477323 1.0 1.0 22 O00170,Q8IY37,A1X283,O14802,Q9P2D1,Q8IWS0 6 +Soft skin 0.3950943712178377 0.433975771527077 0.6643060351666201 1.0 1.0 8 Q13126 1 +Prolonged partial thromboplastin time 0.3950207683666105 0.4336756949596516 0.6645239586326173 1.0 1.0 8 Q92908,Q9BV10 2 +Holoprosencephaly 0.4089846063036977 0.4327548896418619 0.6651928485552909 1.0 1.0 12 A5YKK6,O94979,Q15645,Q92917,Q9P2D1,O43683,O43684 7 +Type i diabetes mellitus 0.405455573489913 0.4321226587862585 0.6656522670704674 1.0 1.0 11 P50851,A5YKK6 2 +Abnormal scapula morphology 0.4450773246647306 0.4308732830419866 0.6665605106898909 1.0 1.0 53 Q06124,P08708,Q14999,Q07020,P62847,O15357,P61353,P62081,P62854,P42766,P60866,Q9Y5L0,P61313,Q08AM6,P61254,P62899,Q13501,Q06210 18 +Abnormality of the voice 0.2111718168721857 0.4308211526739173 0.6665984179117403 1.0 1.0 144 O75569,Q9UPP1,O00170,O95352,P21359,P42356,Q01968,P38935,P28340,O75165,Q9P2D1,O43709,P26196,P42858,Q9Y296,Q96IJ6,P18074,Q06210,Q9Y3I1,P04350,Q06124,Q7Z6Z7,P26639,O60333,P28482,Q9BPU6 26 +Muscular ventricular septal defect 0.381998474032592 0.429725139778883 0.6673955938055982 1.0 1.0 5 Q9BV10,Q5SRE5 2 +Ectropion 0.4074608062961637 0.4265704704517669 0.6696922097674287 1.0 1.0 12 P18074,O14802,P26639 3 +Puberty and gonadal disorders 0.2098333363058452 0.4260965797542269 0.6700374723379658 1.0 1.0 156 Q3SYG4,O00170,Q8IY37,Q93008,O43933,P21359,Q01968,Q13144,P28340,Q9P2D1,O43709,P06737,P26196,P42858,Q9Y296,P27635,P18074,Q8IWS0,Q06124,Q07864,Q7Z6Z7,O14802,Q13315,P22681,Q9NW08,Q15042,Q9BPU6 27 +Narrow iliac wing 0.3766752887886182 0.4258558271126411 0.670212904215503 1.0 1.0 4 Q9NR45 1 +Flat forehead 0.3759419965619524 0.4228773103041473 0.6723847780503607 1.0 1.0 4 Q13555 1 +Dysgraphia 0.415058704763771 0.4191883169764066 0.6750785097351188 1.0 1.0 15 P52701,Q13501,O43709,P54277 4 +Abnormal midbrain morphology 0.3910343421314365 0.4175508710279134 0.6762755232007884 1.0 1.0 8 Q96KP1,Q9Y484,O43924,Q9Y3I1 4 +Abnormal cortical bone morphology 0.4275461132396169 0.4155359670452917 0.6777495910752849 1.0 1.0 20 A1X283,Q00534,P42695 3 +Fine hair 0.422048412912202 0.4135731998640676 0.6791867038277348 1.0 1.0 18 P36507,P49917,O75182,P22681,Q01968,Q6PGP7,Q08J23,P18074 8 +Hand muscle weakness 0.3970955544850534 0.4125018042329738 0.679971658539674 1.0 1.0 10 Q13501,Q9Y223 2 +Hypophosphatemia 0.3893961374573274 0.4109983400168261 0.6810737519053522 1.0 1.0 8 Q01968,O15357 2 +Arthropathy 0.3772677086520038 0.4106260802390465 0.6813467370134163 1.0 1.0 5 P40763,O95163 2 +Hyperactivity 0.2063399584629361 0.4091534727951336 0.6824270365578289 1.0 1.0 167 P68400,P31146,Q93008,P46109,Q08209,P10589,P51532,P21359,Q01968,Q13535,Q6DN90,Q5F1R6,Q9P2D1,P52701,Q9UET6,Q9ULK4,Q15058,O43709,P26196,P42858,Q13045,Q9Y296,Q08J23,Q96F07,Q96F86,Q14353,P49917,O60524,Q7Z6Z7,P42345,Q9NUQ7,P60866,Q9UBB6,Q9UIG0,Q00610,Q05639,Q12830,P49589,Q06787,P28482,Q6NXR4,Q8NC96,Q9C0E8,Q7LBC6,Q9Y223,P46821,Q2M389,Q96C86,Q9BPU6,Q13618,P54277 51 +Abnormality of chromosome segregation 0.3766427718040449 0.4081300994928193 0.6831781631220077 1.0 1.0 5 Q7Z5J4,Q15645,O60566,Q14739 4 +Abnormality of the pulmonary veins 0.388442413393277 0.4072038030820804 0.683858308609429 1.0 1.0 8 Q92908,P60953,P57076,Q86Y56 4 +Uveitis 0.3980165887517705 0.4023113343175428 0.6874549141836526 1.0 1.0 11 P49327,P50851,Q9UDY8 3 +Vitiligo 0.3793724458132762 0.402073387613522 0.6876300174710783 1.0 1.0 6 P50851 1 +Aplastic clavicle 0.3658151021827789 0.4002189553140299 0.6889952544341569 1.0 1.0 3 P48651 1 +Abnormality of the testis size 0.4415026470189708 0.3988301997397596 0.6900183232073043 1.0 1.0 30 O43505,P27635,Q9UPP1,Q14999,Q8IY37,P21359,Q9P2D1,P18074,Q8IWS0,Q9NVI1 10 +Cystic renal dysplasia 0.3604894061474188 0.3972657022579582 0.6911715364272473 1.0 1.0 2 Q8TD19 1 +Low hanging columella 0.3891530411174296 0.3953450442804873 0.6925882607151881 1.0 1.0 9 Q9BTW9 1 +Abnormality of the midface 0.206182291662736 0.3917104959833605 0.6952721338951935 1.0 1.0 163 P36507,O15357,Q15436,Q8IY37,Q93008,O00170,O43933,P21359,Q01968,Q00535,Q12873,Q9BSJ2,A1X283,Q4G0J3,Q9P2J5,Q9P2D1,Q9UET6,Q14999,P17612,P41252,P35573,Q92908,Q9Y4X0,P04350,Q06124,Q07864,P42345,P62854,Q99575,O14802,Q9BV10,O60826,O14646,P28482,P22681,P60953,Q9HC07,Q15042,Q6W2J9,Q01433 40 +Abnormal 5th finger morphology 0.2057120214893585 0.3916509691080275 0.6953161224572098 1.0 1.0 111 Q3SYG4,Q9Y263,O95352,P51532,A1X283,Q13535,Q9P2D1,Q9Y4A5,P57081,Q14999,O43709,P27635,Q06124,Q9Y4X0,P49917,O00443,Q9BV10,P28482,P22681,P46821,Q6W2J9 21 +Abnormal cardiac septum morphology 0.1973844463598358 0.391244657852816 0.6956164015797397 1.0 1.0 210 Q2VPK5,P08708,Q07020,P62847,P61353,Q93008,O43933,P51532,P21359,Q7KZN9,A1X283,Q4G0J3,Q9H3P2,Q9P2D1,Q9Y4A5,Q9NVI1,O43709,P62081,P26196,P42766,Q14839,Q6PGP7,P46777,P27635,O00217,P18074,Q06124,Q9Y4X0,P26639,P62854,P60866,P61313,Q08AM6,Q5SRE5,Q9BV10,Q15477,O60826,P28482,P31939,P61254,P62899,Q6W2J9,Q7LBC6 43 +Sleep disturbance 0.2081775487988945 0.3910612069230889 0.6957519942821075 1.0 1.0 149 O00170,O95352,A5YKK6,Q08209,P21359,P26358,Q6DN90,O75165,Q4G0J3,Q14203,P57081,Q9ULK4,O43709,P06737,P26196,P42858,Q9Y5L0,Q13045,P08397,Q14204,Q9Y296,Q08J23,P67870,Q96F86,Q9Y3I1,Q96QK1,Q96KP1,O60524,Q7Z6Z7,Q9NUQ7,Q9UBB6,Q00610,Q9HCK8,Q05639,Q12830,Q06787,Q04637,Q6NXR4,P40818,Q9Y223,Q9UID3,Q96C86,Q9BPU6,Q2M389 44 +Abnormality of the metopic suture 0.4133542723214936 0.3897667445146616 0.6967090367928235 1.0 1.0 17 P18074,Q5SRE5,P28482,P46821 4 +Cerebral dysmyelination 0.3798495930278336 0.3884720916806108 0.6976667031850123 1.0 1.0 7 P18074 1 +Atrioventricular canal defect 0.3836382837126024 0.3883203910254933 0.6977789490884809 1.0 1.0 8 Q92908,O60826,Q06124 3 +Abnormal superior cerebellar peduncle morphology 0.3581020590868355 0.3878343947598504 0.6981385905329602 1.0 1.0 2 P36405 1 +Elongated superior cerebellar peduncle 0.3581020590868355 0.3878343947598504 0.6981385905329602 1.0 1.0 2 P36405 1 +Abnormality of the pineal gland 0.3711940065131415 0.3866432602069257 0.6990203269637731 1.0 1.0 5 Q12830 1 +Abnormal pineal morphology 0.3711940065131415 0.3866432602069257 0.6990203269637731 1.0 1.0 5 Q12830 1 +Pineal cyst 0.3711940065131415 0.3866432602069257 0.6990203269637731 1.0 1.0 5 Q12830 1 +Down sloping shoulders 0.4307392814595631 0.3862446180811965 0.6993155122562005 1.0 1.0 25 O43709,Q7Z6Z7,Q9BPU6,P42858,Q9Y296,Q9P2D1,Q6W2J9 7 +Bladder neoplasm 0.3830925484566181 0.3862000371912011 0.6993485262027819 1.0 1.0 8 O96017,O14965,P63167,Q9Y620,O43683 5 +Clitoral hypoplasia 0.3739820686972368 0.3809904285327705 0.7032103508216574 1.0 1.0 6 Q15042 1 +Hypoplastic labia minora 0.3739820686972368 0.3809904285327705 0.7032103508216574 1.0 1.0 6 Q15042 1 +Everted upper lip vermilion 0.3647844663870364 0.378645130522571 0.704951403913721 1.0 1.0 4 P46821 1 +Vertebral wedging 0.3596994432112723 0.3762393140494674 0.7067389905473287 1.0 1.0 3 Q15436 1 +Lymphoma 0.4345110002061582 0.3759385173410046 0.7069626046605091 1.0 1.0 29 O96017,P49917,P52701,O95394,Q07864,Q9UDY8,P50851,Q00653,P42771,P49327,P54132,P40763,Q9Y620,Q13315,Q08J23,Q9P2D1 16 +Sloping forehead 0.4354172859696883 0.372658516334331 0.70940261505991 1.0 1.0 51 Q9UPP1,A5YKK6,Q9BSJ2,Q13535,Q9BXW9,Q6UVJ0,Q9NVI1,Q9HC21,P42695,Q9NPF4,Q15058,Q15021,P08243,Q15645,Q00534,Q08J23,P26640,Q96C36,P49917,Q96EK5,Q96KP1,Q92917,Q92979,P47897,Q15003,Q6NXR4,O43684 27 +Abnormal platelet function 0.3670814300390145 0.3707619891296461 0.7108148149424507 1.0 1.0 5 Q06124,O00203 2 +Excessive daytime somnolence 0.3959901016474558 0.3687622428382676 0.7123049500774965 1.0 1.0 13 P42858,P26358 2 +Porokeratosis 0.360796099054862 0.3633515439406854 0.7163422940254871 1.0 1.0 4 P53602,Q9H1A4 2 +Developmental cataract 0.4239307897297215 0.3631829054993765 0.7164682565112583 1.0 1.0 57 P08708,Q07020,P62847,P62081,P61353,P26639,P62854,P42766,P60866,O00443,P61313,Q01968,Q15042,P62899,Q5SRE5,Q6W2J9,P18074,O60333 18 +Congenital malformation of the right heart 0.3909268467278786 0.3619567509239634 0.7173843499276344 1.0 1.0 12 Q92908,A1X283,Q86Y56,Q9P2D1,Q6W2J9 5 +Female hypogonadism 0.3729192294464049 0.3619037033755128 0.7174239923792487 1.0 1.0 7 Q9P2D1,Q13315 2 +Aplasia hypoplasia of the femur 0.4112759321380163 0.3614938984637016 0.7177302653763413 1.0 1.0 19 Q9Y4X0,Q14839,O00443,Q99575,O14802,Q9BV10 6 +Stereotypy 0.3776441887976016 0.3614117847926768 0.7177916395479058 1.0 1.0 73 Q08209,P10589,Q01968,O43776,Q12873,Q4G0J3,Q6DN90,Q9ULK4,P26196,Q13045,Q14204,Q08J23,Q96F86,P67870,O60524,Q7Z6Z7,Q9H7D7,Q9UBB6,Q00610,Q96N67,Q13501,Q05639,Q14738,Q06787,O14646,Q6NXR4,Q96C86,Q9BTW9,Q9BPU6,Q2M389 30 +Loss of ability to walk 0.3971605244835081 0.361278457237682 0.7178912963613859 1.0 1.0 14 Q9H269 1 +Aplasia hypoplasia of the ear 0.4214254809955481 0.3606938153542812 0.7183283485594467 1.0 1.0 58 P08708,Q07020,P62847,P61353,A5YKK6,Q9H3P2,Q9P2D1,P62081,P42766,Q6PGP7,Q07864,P62854,P60866,P61313,O15111,Q16512,P61254,P62899,P63241,P46821 20 +Decreased number of peripheral myelinated nerve fibers 0.4057417281570817 0.3605472797904978 0.7184379064633335 1.0 1.0 17 P50570,P26358,Q9NZJ4,O60333 4 +Abnormal arachnoid mater morphology 0.3834858950690933 0.3597831547814485 0.7190093013463015 1.0 1.0 10 O43776,Q9NZJ4 2 +Focal onset seizure 0.3063738940905014 0.3594109890673578 0.7192876551106488 1.0 1.0 88 P21359,P42356,O43776,P53618,Q9Y6D5,Q14204,P67870,Q96F86,P27635,Q14353,O60524,O94903,P42345,Q96N67,O14802,O14617,P46821,Q96C86,Q9BPU6,Q2M389 20 +Renal agenesis 0.4246014633921975 0.3577185371678625 0.7205539592157537 1.0 1.0 56 Q06124,Q2VPK5,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,O00443,P61313,P61254,P62899,P46777,Q00534,Q9P2D1,P42695 18 +Slow saccadic eye movements 0.3819571624099562 0.3540657351209979 0.7232896202816947 1.0 1.0 10 Q9Y3I1 1 +Hypouricemia 0.3626045400238818 0.3538151389652088 0.7234774272049045 1.0 1.0 5 Q9NQX3,O96007,Q08426,Q9NZB8 4 +Motor seizure 0.2010224763033138 0.3501108488193418 0.7262555093638239 1.0 1.0 107 Q8IY37,O60701,P42356,O43776,Q14746,Q9ULK4,P40763,Q14204,P67870,P27635,Q96F86,Q14353,O60524,O94903,Q9UBB6,Q00610,Q96N67,O14617,O60231,P28482,Q9C0E8,Q96C86,Q9BTW9,Q2M389 24 +Poor speech 0.2816505758064053 0.3496056282094324 0.7266346864833215 1.0 1.0 92 Q93008,Q08209,Q6DN90,Q9Y4A5,Q9UET6,Q9ULK4,Q15058,O60610,P27708,Q14204,Q08J23,P67870,Q96F86,Q14353,P04350,O60524,O94903,Q9NUQ7,Q9UBB6,Q00610,Q96N67,Q13501,Q16512,Q05639,O60826,Q7Z392,Q9BTW9,P60953,Q96C86,Q14738,Q2M389 31 +Demyelinating peripheral neuropathy 0.3997504958308647 0.3486724838199787 0.7273352041057641 1.0 1.0 16 P35251,Q5TBB1,P18074,Q9NZJ4 4 +Malignant neoplasm of the central nervous system 0.4206760419976087 0.3474017454580352 0.7282895222205408 1.0 1.0 25 Q06124,O96017,P52701,P20585,P42771,P21359,P54277,O60333 8 +Pulmonic stenosis 0.4317483629811784 0.3471556821738812 0.7284743632486435 1.0 1.0 33 Q92908,P36507,Q06124,Q12830,O60826,O43709,P61353,P60953,P21359,Q6PGP7,O14802,Q9P2D1,Q6W2J9,Q13618 14 +Periventricular heterotopia 0.3833590826020371 0.346339694262179 0.7290874406436345 1.0 1.0 11 O60231,Q9Y6D5,P46821 3 +Hypermethioninemia 0.3605845989072183 0.3462884354868927 0.7291259587628653 1.0 1.0 5 Q6PGP7,P16930 2 +Cerebral hypomyelination 0.4043878553300666 0.3454078229160899 0.7297877968357755 1.0 1.0 18 P04350,Q9NW08,P49770,Q13144,P54136,Q9BTW9 6 +Sparse and thin eyebrow 0.3830669168020871 0.3452634702766447 0.7298963065263633 1.0 1.0 11 Q96EK5,O14802,P46778 3 +Mild global developmental delay 0.4012644090108805 0.3438603696118871 0.7309512969237915 1.0 1.0 17 O00203,P41252,Q01968,Q13535,P46821 5 +Large face 0.3812396277456991 0.3407850092887364 0.7332654365350586 1.0 1.0 71 P36507,Q9UPP1,O00170,O95352,P21359,Q01968,P17612,P26196,P42858,Q13045,Q9Y296,P27635,Q06210,Q9BUK6,Q9NZB8,Q7Z6Z7,O43924,Q9BV10,Q16512,Q12830,Q06787,P28482,Q6PJG6,Q6W2J9,Q14738,Q9BPU6 26 +Aplasia hypoplasia involving the pelvis 0.4055872231690871 0.3402731392663102 0.7336508433130986 1.0 1.0 19 Q14999,O15357,O00443,Q14839,Q99575,Q9H3P2 6 +Absent septum pellucidum 0.4287253062201298 0.3393607663397841 0.7343379706678435 1.0 1.0 32 O43505,O60524,Q9ULK4,Q96C86,Q9BZH6,Q9UBB6,P48651,Q6DN90,Q08J23,Q96F86,Q2M389,Q9NVI1 12 +Abnormal shoulder morphology 0.4285046900964915 0.3385206346747875 0.7349708797904735 1.0 1.0 32 O43709,Q7Z6Z7,P42858,Q6W2J9,Q9Y296,Q9P2D1,Q9BPU6,Q9Y6D5,P46821 9 +Aplasia hypoplasia of the tragus 0.3485815302338998 0.3343520686144801 0.738113903816739 1.0 1.0 3 Q5SRE5 1 +Abnormality of the tragus 0.3485815302338998 0.3343520686144801 0.738113903816739 1.0 1.0 3 Q5SRE5 1 +Pleural effusion 0.3831054448216038 0.3330873069924683 0.7390683804052931 1.0 1.0 12 Q06124,P49327,P14174,Q9UID3 4 +Enlarged thorax 0.392521980378262 0.3329258661021155 0.7391902438393425 1.0 1.0 15 Q06124,P28482,Q14999,Q99575,Q92917,Q6W2J9 6 +Anal stenosis 0.3600536478290405 0.3289002864833385 0.7422310577678142 1.0 1.0 6 P49917,Q9P2D1 2 +Sarcoma 0.4056930505274129 0.3288425159065439 0.742274725526489 1.0 1.0 62 P08708,Q07020,P62847,P61353,P21359,P49327,P42771,Q13126,O14965,P52701,P62081,P42766,Q01844,Q06124,P62854,P60866,P61313,Q13501,O96017,P62899 20 +Abnormality of the nasal alae 0.1986078487491615 0.3271937651961856 0.7435213362554158 1.0 1.0 174 P36507,Q9UPP1,P68400,O15357,Q8IY37,Q93008,O43933,P10589,P51532,P21359,O75909,A1X283,Q9Y4A5,P57081,Q9UET6,Q14999,Q6PGP7,P35573,P18074,Q9Y4X0,Q7Z6Z7,O00443,Q96N67,Q08AM6,O14802,P28482,P29372,P31939,P60953,Q15042,P63241,Q6W2J9,Q9UID3,Q7LBC6,Q6P2Q9 35 +Neonatal hypoglycemia 0.3733829377507854 0.3228072156016051 0.7468412480664199 1.0 1.0 10 O43772,P31751 2 +Olivopontocerebellar hypoplasia 0.3444776119403046 0.3194771793685075 0.7493646936487439 1.0 1.0 3 Q9UNW1,Q96GM8 2 +Brittle hair 0.3916610681762746 0.3193254588705337 0.7494797290645141 1.0 1.0 16 P36507,P49589,P26639,Q15436,P62266,Q6PGP7,P18074,Q15477 8 +Abnormality of the 2nd toe 0.3757375801150349 0.3187958594972966 0.7498813182365276 1.0 1.0 11 Q93008,Q6W2J9 2 +Saccadic oscillation 0.3485702711291082 0.3182935640987546 0.7502622657711113 1.0 1.0 4 O60333 1 +Agenesis of lateral incisor 0.3434994286638035 0.3159801899510784 0.7520175445210742 1.0 1.0 3 Q6W2J9 1 +Deviation of the hand or of fingers of the hand 0.2015211432341147 0.312316295232615 0.7548001571930225 1.0 1.0 121 Q2VPK5,O95352,O43933,P42356,A1X283,Q13535,Q9P2D1,Q9Y4A5,P57081,Q14999,O43709,P27635,P78527,Q06124,Q9Y4X0,P49917,Q9BV10,P28482,P22681,Q9BPU6,Q15042,P46821,Q6W2J9 23 +Aplasia hypoplasia of the abdominal wall musculature 0.3507957321777649 0.3109079968166043 0.7558705649813278 1.0 1.0 5 Q06124 1 +Skin rash 0.4037506963756303 0.3080327828801868 0.7580573872231748 1.0 1.0 22 P22681,P14174,P50747,Q96BN8,Q9H4L7,Q5F1R6,P18074 7 +Aplasia hypoplasia of the ribs 0.4097876835931532 0.3076426927922058 0.7583542305001187 1.0 1.0 25 Q06124,O60826,Q14999,Q08AM6,Q13535,Q9BV10 6 +Flared nostrils 0.3496113730390776 0.3067540125942494 0.7590306142836525 1.0 1.0 5 Q93008 1 +Abnormal localization of kidney 0.3956253392508582 0.3055810004428772 0.7599236883622567 1.0 1.0 64 P08708,Q07020,P62847,P61353,Q93008,P51532,Q9P2D1,Q9NVI1,O43709,P62081,P26196,P42766,Q06124,P62854,P60866,P61313,O15111,P61254,Q15042,P62899 20 +Myopia 0.1967508764656556 0.3053570697514151 0.7600942146679852 1.0 1.0 106 P36507,Q93008,P10589,P51532,Q5F1R6,Q9NVI1,O43709,O95163,P42858,Q13045,P61586,Q08J23,P27635,P26640,Q10567,P18074,Q06124,Q9Y4X0,P49917,Q7Z6Z7,P26639,Q9H7D7,Q9UIG0,Q8NCH0,O14802,Q12830,Q7Z392,Q13555,Q9NW08,Q9H582,Q14738 31 +Aplasia hypoplasia of the ulna 0.3752394018723409 0.3052353908141597 0.7601868797446578 1.0 1.0 12 P61254,Q14999,Q9P2D1 3 +Abnormal anterior horn cell morphology 0.3569113682594492 0.3039194522102919 0.7611892576246069 1.0 1.0 7 P38935 1 +Leukemia 0.3996865343951846 0.3014013896887581 0.7631084347378372 1.0 1.0 62 Q06124,P49917,O96017,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P22681,P61313,P21359,P42771,P62899,Q13315,Q5F1R6 18 +Female reproductive system neoplasm 0.3995722458000141 0.3013836549707869 0.7631219566853467 1.0 1.0 21 O96017,O14965,P52701,Q07864,P60866,P20585,P28340 7 +Nasogastric tube feeding 0.4078729635247942 0.3009061011934533 0.76348609773666 1.0 1.0 25 O60524,Q9ULK4,Q96C86,Q9UBB6,Q6DN90,Q08J23,Q96F86,Q2M389 8 +Functional abnormality of the gastrointestinal tract 0.1856378352865862 0.3007025186294117 0.7636413480395914 1.0 1.0 291 O75569,Q9Y263,Q93008,O95352,P42771,P42356,P21359,Q01968,P49327,O75165,Q9P2D1,Q9UER7,Q9Y6D5,P52701,O43709,P07814,P42858,Q9Y5L0,P41252,Q14204,Q6PGP7,Q01844,Q96IJ6,Q96F07,P27635,P26640,P67870,P18074,Q06210,Q9Y3I1,P04350,P57678,Q9NZJ4,O00203,P60866,Q00610,Q08AM6,O14802,Q9BV10,Q13501,Q15477,Q16512,O60826,P28482,P29372,P22681,Q9NW08,P50851,P46821,Q9BTW9,Q9BPU6,P54277 52 +Pseudobulbar signs 0.3667599084094666 0.2996365298802178 0.7644544168820806 1.0 1.0 10 P26358 1 +Abnormal urinary electrolyte concentration 0.3966773742522445 0.2996288099802175 0.764460306082225 1.0 1.0 20 Q9Y4X0,O43709,O00443,Q01968,Q9UBS4 5 +Young adult onset 0.3698726431877132 0.2983728218369154 0.7654186299146115 1.0 1.0 11 Q9Y3I1 1 +Abnormal cornea morphology 0.2003222156017489 0.2972397516850916 0.7662834750722338 1.0 1.0 157 O75569,Q3SYG4,Q93008,O43933,P10589,Q01968,P49327,Q12873,A1X283,Q9H3P2,Q5F1R6,Q9NVI1,O43709,P26196,Q14839,P42858,Q9Y296,P26640,P18074,Q96EK5,O43505,Q7Z6Z7,P26639,P50747,Q08AM6,O14802,O15111,Q15042,Q6W2J9,Q9BPU6 30 +Impaired smooth pursuit 0.3877775940988137 0.2959530990493579 0.7672658992161334 1.0 1.0 17 P35251,Q9NW08,Q9NZJ4 3 +Beaking of vertebral bodies 0.361762627367366 0.2948197279853761 0.7681315951618679 1.0 1.0 9 A1X283 1 +Calcification of the aorta 0.3455186915011171 0.2926167966627279 0.7698150735913738 1.0 1.0 5 Q5TBB1 1 +Abscess 0.3570425974821961 0.2913355233391997 0.7707947214628055 1.0 1.0 8 O95394,P42771 2 +Akinesia 0.3606375610105228 0.2910005146050115 0.7710509259334488 1.0 1.0 9 Q14203,O75165,Q04637 3 +Migraine 0.400300425254412 0.2885948848330905 0.7728914103407354 1.0 1.0 23 P52701,O00170,P60866,Q9NQZ5,P21359,P49327,P53618,P54277 8 +Annular pancreas 0.3355223880597101 0.2881792155851475 0.7732095577932141 1.0 1.0 3 Q9Y4R8,Q9BXW9 2 +Abnormal rectum morphology 0.4143322223367614 0.2867852979322707 0.7742767208591119 1.0 1.0 32 O96017,P49917,P52701,O43709,Q07864,P20585,P42771,P28340,Q6W2J9,P54277 10 +Widow s peak 0.3388757029919945 0.2846388641475681 0.7759208330461722 1.0 1.0 4 P29372 1 +Abnormality of the pulmonary artery 0.4164592951336152 0.2842840543932495 0.7761927050072484 1.0 1.0 35 Q06124,O43709,Q7Z6Z7,P22681,P26196,P42858,Q6PGP7,Q6W2J9,Q9Y296,P27635,Q9BPU6,Q15477 12 +Abnormal blood transition element cation concentration 0.3723225387882276 0.2842153264516712 0.7762453707677852 1.0 1.0 13 Q14746,P41252,Q15477 3 +Parakeratosis 0.3428912783751309 0.2837214699213952 0.77662383995536 1.0 1.0 5 P53602,P15924,Q15126,P00338 4 +Abnormal pulmonary valve physiology 0.4173626087992987 0.28098964153211 0.778718344761298 1.0 1.0 38 Q92908,P36507,Q06124,Q12830,O60826,O43709,P61353,P60953,P21359,Q6PGP7,O14802,Q9P2D1,Q86TI2,Q6W2J9 14 +Abnormal stomach morphology 0.3051072121295102 0.2780360219345597 0.7809847069843927 1.0 1.0 86 Q93008,O43933,P20585,P42771,P49327,Q9Y6D5,P57081,P52701,O14965,O43709,Q6PGP7,P50570,Q08AM6,Q15477,O96017,P28482,P50851,P46821,Q6W2J9,Q8NCE2 20 +Toe clinodactyly 0.4024108572630007 0.2759045774235009 0.7826213580538037 1.0 1.0 26 Q7Z6Z7,Q93008,P26196,P42858,Q9Y296,Q9BPU6 6 +Craniofacial hyperostosis 0.3438139648088297 0.2728888454348111 0.7849386612690861 1.0 1.0 6 P18074 1 +Poor coordination 0.3622438566781827 0.2728550792781409 0.7849646181857528 1.0 1.0 11 Q99707 1 +Hypoplastic vertebral bodies 0.3436447663129147 0.2723337465394581 0.7853654104591767 1.0 1.0 6 O14802 1 +Hypoplasia of the radius 0.3584563551640294 0.2718434889853219 0.7857423645495463 1.0 1.0 10 Q9BV10,Q13535,P61254 3 +Protruding ear 0.4147677817999593 0.2717289234369481 0.7858304600897761 1.0 1.0 46 Q06124,P49917,O43505,O43709,Q14999,Q7Z6Z7,P26639,Q8IY37,P10589,P21359,Q01968,Q00610,A1X283,P27635,P18074 15 +Acute leukemia 0.4126463588661954 0.2707741800118226 0.7865647196200563 1.0 1.0 49 O96017,P49917,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61313,P42771,P62899,Q5F1R6 14 +Abnormality of the pulmonary vasculature 0.4152426649683217 0.270478977439 0.7867917879714561 1.0 1.0 41 Q92908,Q06124,P57076,O43709,Q7Z6Z7,P22681,P26196,P42858,Q6PGP7,Q6W2J9,Q9Y296,Q86Y56,P27635,Q9BPU6,Q15477 15 +Azoospermia 0.3699707361307665 0.2661481768294909 0.7901250928154224 1.0 1.0 14 Q8IY37,P54132,Q01968,Q9P2D1,Q9NVI1 5 +Abnormal size of the palpebral fissures 0.2760339048588687 0.264927823263309 0.7910650640554029 1.0 1.0 91 O60701,Q93008,O75909,Q13535,Q4G0J3,Q9NVI1,O43709,P26196,Q14839,P42858,Q9Y296,P27635,Q8IWS0,P49917,Q7Z6Z7,Q92917,Q13555,P28482,Q9BPU6,P63241,Q6W2J9 21 +Abnormal paranasal sinus morphology 0.394108625718184 0.2611730162879711 0.7939590860205783 1.0 1.0 24 P57076,O95394,Q06787,Q13432,P50851,Q00653,Q03518,P21359,Q13315,Q5F1R6,Q86Y56 11 +Thin skin 0.3970192467598515 0.2581792795677863 0.7962685484768013 1.0 1.0 26 Q06787,O00170,P40818,Q9H4L7,O14802,Q13126,Q9Y6D5,P18074,O15111,P46821 10 +Exercise induced rhabdomyolysis 0.3256716417910486 0.2556775059145962 0.7981998656550011 1.0 1.0 3 P04075,P00338 2 +Abnormal dental pulp morphology 0.3532897006910086 0.2552811681663418 0.7985059438298798 1.0 1.0 10 O43933,P21359 2 +Low posterior hairline 0.4081848922451196 0.2534426183615796 0.7999261977044378 1.0 1.0 36 Q06124,Q9NR45,O60826,Q9UPP1,P28482,Q7Z6Z7,P22681,O00443,Q15042,P21359,Q9Y223,Q9H3P2,Q9BV10,Q9UID3 14 +Duodenal atresia 0.3490056035935662 0.2530627849247234 0.8002196963454133 1.0 1.0 9 Q15645,Q9P2D1,Q7LBC6,O43683,O43684 5 +Mild microcephaly 0.3449667352634549 0.2519428476841194 0.8010852398943435 1.0 1.0 8 Q69YN2,Q4G0J3 2 +Heterophoria 0.318710832587288 0.2477572098254534 0.8043222644222974 1.0 1.0 2 Q7Z392 1 +Horseshoe kidney 0.4081216872328792 0.2468212312338026 0.8050465785945511 1.0 1.0 45 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P51532,P62899,Q9P2D1,O15111,Q9NVI1 15 +Upper limb undergrowth 0.3825535897884712 0.2454518371851589 0.8061065959901736 1.0 1.0 21 Q14999,P61254,Q13535,Q9BV10,Q9P2D1,O15111 6 +Abnormality of the musculature of the upper limbs 0.3393525190743411 0.2420766074823063 0.8087208037323623 1.0 1.0 77 Q06124,P08708,Q14999,Q07020,P62847,P62081,P61353,P62854,P50570,P42766,P60866,P62899,P61313,Q9Y5L0,Q96IJ6,Q13501,Q8NCE2,Q06210 18 +Death in adulthood 0.3622676864250218 0.2419805320913113 0.8087952481621989 1.0 1.0 14 P52701,P54277 2 +Abnormality of pelvic girdle bone morphology 0.1962349277242772 0.2419452148562049 0.8088226143087636 1.0 1.0 149 O15357,Q93008,Q01968,A1X283,Q13535,Q9H3P2,Q5F1R6,Q9NVI1,Q14999,O43709,P26196,Q14839,P42858,Q9Y296,Q8IWS0,Q7Z6Z7,P57678,O00203,O00443,Q99575,Q08AM6,O14802,O60826,Q9BPU6,Q9BTW9,Q7LBC6 26 +Hypoplastic ilia 0.3484921058827471 0.24041858285998 0.8100057735702517 1.0 1.0 10 O14802,Q99575 2 +Respiratory tract infection 0.194581111049671 0.2400187748844275 0.8103157017228988 1.0 1.0 163 Q9NPL8,O15357,Q93008,P51532,Q01968,Q9H3P2,Q86Y56,Q9P2R3,Q9P2D1,Q5F1R6,Q9Y5K6,Q9NRZ9,O43709,P14174,P17812,O95163,P40763,P78527,P18074,P49917,Q07864,P26639,O00203,O14802,Q13315,Q9BV10,Q9UDY8,O60826,O14617,P28482,P50851,P29144,Q9UID3,Q9BTW9 34 +Ectopic kidney 0.3644876827084551 0.2394388361662263 0.810765318729409 1.0 1.0 15 Q93008,P62854,O43709 3 +Duplication of hand bones 0.3909650167033051 0.2392253151076837 0.8109308738487944 1.0 1.0 59 O60826,P08708,Q9UPP1,Q3SYG4,Q07020,P62847,Q9Y263,P61353,P62081,P60866,P42766,P62854,P61313,P61254,P62899,Q9H3P2,Q9P2D1,Q6W2J9 18 +Keratoconjunctivitis 0.3474331391136597 0.2372060542039136 0.8124969397608723 1.0 1.0 10 P49327,P18074,P26639 3 +Cystic hygroma 0.3362600017591041 0.2367651470473186 0.8128389914543903 1.0 1.0 7 Q06124 1 +Thoracic kyphosis 0.3633000545280134 0.2358493474281711 0.813549574370052 1.0 1.0 15 Q9UPP1,O00443,Q99575,O43776,P18074 5 +Sagittal craniosynostosis 0.3227829202747075 0.2331410810264367 0.8156518556561911 1.0 1.0 4 P18583,P21281,P61978 3 +Abnormality of the antihelix 0.3495371815573329 0.2330992975701216 0.81568430034041 1.0 1.0 11 P49917,P27635,Q15042 3 +Abnormal spermatogenesis 0.3649404825500228 0.2319240160150315 0.816597030950458 1.0 1.0 16 Q8IY37,P54132,Q01968,Q13315,Q9P2D1,Q9NVI1 6 +Lack of skin elasticity 0.3614159156878128 0.2302192895514128 0.8179213734961228 1.0 1.0 15 O00170,Q9H4L7,P53618,P28340,Q15334 5 +Metatarsus adductus 0.3698986502397231 0.2300485785528009 0.8180540216140917 1.0 1.0 18 Q08AM6,O43933,A1X283,P28482 4 +Neoplasm of the respiratory system 0.3641141305050163 0.229468000083063 0.8185051893392117 1.0 1.0 16 O96017,Q01844,P42771 3 +Aortic arch aneurysm 0.3365616674692143 0.22638459632465 0.8209023073243664 1.0 1.0 8 Q9P2D1 1 +Abnormality of refraction 0.1947361697542961 0.226269784977755 0.8209915970983059 1.0 1.0 150 Q3SYG4,Q93008,P10589,P51532,Q12873,Q5F1R6,Q9NVI1,O43709,P07814,P26196,Q14839,P42858,Q9Y296,P27635,P26640,P18074,Q06124,Q9Y4X0,P49917,Q7Z6Z7,P26639,O14802,Q13555,Q9NW08,Q9BPU6 25 +Diastasis recti 0.3199507838911896 0.2246695117162696 0.8222363843933982 1.0 1.0 4 Q8NCH0,P42345 2 +Abnormal circulating progesterone level 0.3279817839411824 0.2236331386968836 0.8230427756960781 1.0 1.0 6 Q13144 1 +Decreased circulating progesterone 0.3279817839411824 0.2236331386968836 0.8230427756960781 1.0 1.0 6 Q13144 1 +Delayed ability to sit 0.3644296374715349 0.2220345814149814 0.8242869630701686 1.0 1.0 17 Q9H7D7,O60701,O43776,Q9UID3,Q9BPU6,Q13618 6 +Neoplasm of the breast 0.3930618210489288 0.2216286336612727 0.8246029903301562 1.0 1.0 31 O96017,P52701,Q07864,P42771,P21359,Q13535,P28340,Q13315 8 +Parkinsonism with favorable response to dopaminergic medication 0.3416655448740611 0.2201477231742636 0.8257561086547955 1.0 1.0 10 Q9Y3I1 1 +Joint contractures involving the joints of the feet 0.3415266206866336 0.2197460510463522 0.8260689375805412 1.0 1.0 10 Q6W2J9,Q8IWS0,P63241 3 +Infantile onset 0.187416948464288 0.2191271344422361 0.8265510141503036 1.0 1.0 192 Q9NPL8,O95352,O43776,Q12873,P53618,Q86Y56,Q9Y6D5,Q14746,Q9UPN3,Q8N8R5,P27708,Q96BN8,P40763,Q96F86,P26640,P78527,Q9Y6B6,Q06210,Q9Y4X0,Q969U7,O60524,Q7Z6Z7,Q9NZJ4,P57678,P42345,P62854,Q9UBB6,Q96N67,Q69YN2,Q16512,O14646,Q99707,P29144,Q15334,Q7Z460,Q9BTW9 36 +Disinhibition 0.3942189457342465 0.218697792624965 0.8268854685963973 1.0 1.0 53 Q08209,P26358,Q6DN90,O75165,Q14203,Q9ULK4,P42858,Q96F07,Q08J23,Q96F86,Q9H269,Q96QK1,O60524,Q9UBB6,Q00610,Q13501,Q05639,Q06787,Q04637,Q8NC96,Q96C86,Q9BPU6,Q2M389 23 +Gonadal neoplasm 0.3867316323210017 0.2159385643344959 0.8290356361811431 1.0 1.0 28 O96017,Q8IY37,P20585,P42771,Q01844,P54277 6 +Nephrolithiasis 0.3793296039284045 0.2159175453305969 0.8290520204746179 1.0 1.0 24 P00492,P07741,O43709,Q9NZB8,O00170,P40818,Q9UIG0,Q01968,Q8NCH0,Q4J6C6,Q9UBS4 11 +Narrow face 0.398156167385981 0.2147695041624646 0.8299470302273646 1.0 1.0 40 P04350,P36507,P49917,Q12830,Q06787,O43709,Q7Z6Z7,P26196,P42858,P54132,Q6W2J9,Q13535,Q9Y296,Q08J23,Q9P2D1,Q9BPU6 16 +Abnormal astrocyte morphology 0.3615033321961037 0.2136235139745973 0.8308406611556722 1.0 1.0 17 O96017,P52701,P20585,P21359,P42771,Q13501 6 +Decreased absent ankle reflexes 0.3553235357162974 0.2125619634708617 0.8316686421518151 1.0 1.0 15 Q13501,Q9Y223,Q9NZJ4 3 +Areflexia 0.2447978431529733 0.2118243765377749 0.8322440502998425 1.0 1.0 95 O43505,O60231,O00764,Q9NZJ4,P50570,O60701,O43933,Q13501,Q06210,P35251,Q01968,Q5TAQ9,P38935,O95248,Q9BTW9,Q8NCE2,Q9Y6B6,O60333 18 +Paroxysmal bursts of laughter 0.3067740972843961 0.2117844934617004 0.8322751665489889 1.0 1.0 2 Q05086 1 +Abnormal phalangeal joint morphology of the hand 0.3975611220126781 0.2113892838103481 0.8325835180972161 1.0 1.0 43 P57081,P28482,O43933,Q15042,Q01968,Q9H4L7,P38935,A1X283,O14802,P27635,Q6W2J9,P18074 12 +Broad face 0.3147208121827341 0.2095062328708271 0.8340530702233804 1.0 1.0 4 Q7Z5J4,O75369,Q6PJG6 3 +Depressed nasal tip 0.3147208121827331 0.2095062328708242 0.8340530702233826 1.0 1.0 4 Q96KP1,Q03164,Q01082 3 +Sclerosis of skull base 0.3147208121827275 0.2095062328708086 0.8340530702233948 1.0 1.0 4 P48651,O43318,Q14739 3 +Hypochromic microcytic anemia 0.3146547344217623 0.209318680822738 0.8341994695869199 1.0 1.0 4 Q8N8R5 1 +Late onset 0.3337129636431419 0.2076701589709864 0.8354865193791374 1.0 1.0 9 P17096 1 +Absent toenail 0.3261540232387726 0.2072992680707226 0.835776145727616 1.0 1.0 7 P28482 1 +Abnormality of the parathyroid morphology 0.3220487871752545 0.2066159991003014 0.8363097643999331 1.0 1.0 6 P21359 1 +Shortening of all distal phalanges of the fingers 0.3393939348723397 0.2039332359372537 0.8384056722905404 1.0 1.0 11 Q93008,Q8IWS0 2 +Broad forehead 0.3948619880386619 0.2036783634356901 0.8386048512409674 1.0 1.0 45 Q9Y4X0,O60826,O43709,Q14999,Q07864,O00170,P21359,O43776,A1X283,Q6PGP7,O14802,P27635,Q15477 13 +Papilloma 0.3392894692995905 0.2036450273763599 0.8386309036249096 1.0 1.0 11 P18074,P20585 2 +Bilateral cryptorchidism 0.3352626733797978 0.2020910605155239 0.8398455363605395 1.0 1.0 10 Q07864 1 +Dysgammaglobulinemia 0.3074626865671676 0.2012527140075153 0.8405009747792487 1.0 1.0 3 O60934,P98170 2 +Abnormality of the frontal hairline 0.3224590804506435 0.2007559434920853 0.8408894135088805 1.0 1.0 79 P08708,Q07020,P62847,P61353,O43933,P51532,O75909,Q9H3P2,Q9NR45,P62081,P42766,P49917,P62854,P60866,O00443,P61313,Q96N67,P29372,P61254,P62899 20 +Dry skin 0.3888005434713386 0.1990403477376313 0.8422311830478826 1.0 1.0 34 P36507,P49917,P28482,P26639,Q5TBB1,P42771,P11802,Q9H4L7,Q6PGP7,Q08J23,Q9P2D1,Q9Y3Z3,P18074,Q15477 14 +Aplasia hypoplasia involving the femoral head and neck 0.3404358909266497 0.1975948705191958 0.8433620484121072 1.0 1.0 12 Q14839,Q99575,O00443 3 +Abnormality of mouth size 0.1911420677225319 0.1974291241362974 0.8434917403536533 1.0 1.0 126 A1X283,P28340,Q4G0J3,Q9P2D1,Q9Y4A5,P57081,O43709,P26196,P42858,Q6PGP7,Q9Y296,P27635,Q9Y4X0,P49917,Q7Z6Z7,P42345,O14802,P28482,Q9BPU6,Q15042,Q96C86,Q7LBC6 22 +Thick nasal alae 0.3497855833911416 0.1972465468424994 0.8436346069277441 1.0 1.0 15 O75909,O00443 2 +Gray matter heterotopia 0.3817151732868076 0.1971230530729755 0.8437312436126128 1.0 1.0 29 O43505,O60231,Q15058,Q06787,O00139,O43933,P46821,Q9BSJ2,P43034,Q00534,Q9Y6D5,P42695 12 +Abnormal labia minora morphology 0.3260526238345871 0.1966651326592363 0.8440895972801647 1.0 1.0 8 Q15042,P31939 2 +Acanthosis nigricans 0.3398702316076077 0.1960683259337041 0.8445566873018666 1.0 1.0 12 O00170,P53618,O14802,O43933 4 +Central hypothyroidism 0.3294259939557033 0.1958953010018156 0.8446921152715099 1.0 1.0 9 P27635,O14654 2 +Absent speech 0.1880154698825194 0.1957807643916312 0.8447817664988935 1.0 1.0 113 P68400,O95352,Q08209,P10589,P51532,P53618,Q9Y4A5,P57081,Q9UPN3,Q15021,P42858,P41252,Q96F07,P27635,Q7Z6Z7,P57678,Q53FT3,O00429,Q05639,Q6PJG6,Q9BTW9,P60953,Q9C0E8,Q96C86,Q14738,Q9BPU6 26 +Abnormal t wave 0.3096896600015686 0.1955165652397002 0.8449885707350351 1.0 1.0 4 Q99996 1 +Macrotia 0.2752612024261032 0.1950122970345931 0.8453833207999766 1.0 1.0 89 Q2VPK5,O00170,O43776,P57081,Q9UET6,O43709,P26196,P42858,P08243,Q9Y296,P27635,Q8IWS0,Q96EK5,Q7Z6Z7,O14617,Q06787,P22681,Q15042,Q9BTW9,Q9BPU6 20 +Abnormality of thyroid physiology 0.3128606027407363 0.194831432744483 0.8455249140273713 1.0 1.0 81 Q9Y263,O00170,Q5TBB1,Q93008,Q9P2D1,Q9Y3Z3,Q9NVI1,P57081,O43709,Q13045,P40763,Q6PGP7,P27635,O14654,Q92908,P49917,Q9BUK6,O00443,O14802,Q15477,Q06787,P50851,Q9Y223,Q6W2J9 24 +Biparietal narrowing 0.3358977582372174 0.1944241458843945 0.8458437849551006 1.0 1.0 11 P36507,O43924,P49917 3 +Difficulty running 0.3391551472487978 0.1941491075421488 0.8460591308420535 1.0 1.0 12 Q14204,Q9Y5L0 2 +Abnormality of facial soft tissue 0.1892730174709378 0.1926256506771353 0.8472521547952387 1.0 1.0 119 Q9Y263,O00170,Q93008,O43933,Q13614,P42356,Q9P2R3,O75165,Q9P2D1,Q9Y5K6,Q9H1B7,P52701,O43709,Q06210,Q9Y3I1,Q9BUK6,P50570,O14802,Q13501,O60826,Q13555,P29144,Q8NCE2,Q01433 24 +Vaginal neoplasm 0.3127022234899849 0.192283803511376 0.84751990460133 1.0 1.0 5 Q15645,O43683,O43684 3 +Severely reduced visual acuity 0.2993136377200878 0.190978182931805 0.8485426860513456 1.0 1.0 2 P20839 1 +Progressive visual field defects 0.2993136377200861 0.1909781829318007 0.848542686051349 1.0 1.0 2 O43395 1 +Abnormal circulating sulfur amino acid concentration 0.3238373011797761 0.1907242912881635 0.8487416063277908 1.0 1.0 8 Q6PGP7,Q99707 2 +Abnormality of the helix 0.3902639128525722 0.1895474316667943 0.8496637837166763 1.0 1.0 43 Q06124,Q9Y4X0,P62266,P26196,O43933,P10589,P21359,Q96N67,O43776,Q6W2J9,P46821,Q9P2D1,Q9UID3,O15111 14 +Prominent supraorbital ridges 0.3403784230147282 0.1887491965772737 0.8502893912505836 1.0 1.0 13 P36507,Q9UPP1,Q8IWS0,Q9HCK8 4 +Abnormal shape of the frontal region 0.186788197122559 0.1853504457280026 0.8529541734605197 1.0 1.0 113 P36507,O15357,Q15436,O00170,Q01968,P48651,Q12873,Q9H3P2,Q9P2J5,Q9NVI1,Q14999,P26196,Q13045,P40763,Q6PGP7,Q07864,Q9NZB8,P42345,O43924,O14802,Q16512,O60826,Q06787,O14646,Q9BTW9,P29372,P22681,P31939,P63241,Q9Y223,Q14738 31 +Enlarged kidney 0.3174996102965545 0.1839267245449598 0.854070939292082 1.0 1.0 7 Q8TD19,P16930,Q9UBS4 3 +Nephrocalcinosis 0.3677007841691638 0.183902430691116 0.8540899979170153 1.0 1.0 24 Q9Y4X0,P16930,O43709,O00443,Q9UIG0,Q01968,Q9UNF1,Q5F1R6,Q96Q11 9 +Hypogonadotropic hypogonadism 0.3733837225205146 0.1836013144180065 0.8543262318954512 1.0 1.0 27 Q06124,O43709,O00170,Q8IY37,Q9NW08,Q15042,O14802,Q9P2D1 8 +Tonic seizure 0.369609534735667 0.1835671292372699 0.8543530519336582 1.0 1.0 25 Q05639,Q14746,P27635,Q08209,Q00610,Q96N67,Q14204,P67870,Q9BTW9,Q13618,P43034 11 +Flexion contracture of digit 0.336765491303802 0.1830525413464953 0.8547567930038298 1.0 1.0 74 O43933,Q01968,P38935,A1X283,Q9P2D1,P57081,P27635,P18074,Q8IWS0,Q7Z6Z7,Q9H4L7,Q5SRE5,O14802,Q92917,Q9BV10,O60826,P28482,Q15042,Q6W2J9 19 +Narrow forehead 0.3864013537014238 0.183020922160564 0.8547816023764698 1.0 1.0 49 P47897,P36507,P49917,Q2VPK5,Q13555,P28482,P60953,Q93008,P26196,Q15042,P21359,Q96N67,Q5SRE5,Q9Y296,Q9BTW9,Q01433 16 +Neoplasm of the pituitary gland 0.3436509859535844 0.1811094954317841 0.856281631572098 1.0 1.0 15 P52701,O00170,P60866,Q9UBS4,P54277 5 +Heat intolerance 0.312518673438892 0.1809838059050219 0.8563802871225203 1.0 1.0 6 P36507,Q05086,Q14571,P61978,P00338 5 +Abnormality of the nail 0.1884799135450916 0.1803124869693309 0.8569072531543991 1.0 1.0 122 O15357,O00170,Q8IY37,O43933,Q13535,Q5F1R6,Q9Y4A5,O43709,P18074,P49917,Q7Z6Z7,P26639,Q99575,Q08AM6,Q9H4L7,O14802,Q9BV10,O75182,O60826,Q13555,P28482,Q15042,P63241 23 +Abdominal distention 0.3661471218567251 0.1798696148523154 0.8572549299498795 1.0 1.0 24 P06737,O15357,P42345,Q8N8R5,Q9Y5L0,Q01844,Q9Y6B6 7 +Epiretinal membrane 0.2994029850746318 0.1796170261133108 0.8574532371695596 1.0 1.0 3 Q96Q11,P04439 2 +Abnormal blood potassium concentration 0.3399699896126978 0.1795234939434931 0.8575266714855887 1.0 1.0 14 O00170,P40818,Q99996,Q01968,Q9UNF1 5 +Prolonged bleeding time 0.3193481440824925 0.1790363813401775 0.857909135016397 1.0 1.0 8 P35579,P36507,P21359,O00203 4 +Abnormality of vitamin k metabolism 0.3116416167382661 0.1787317072402389 0.8581483712702438 1.0 1.0 6 Q13043,Q5F1R6 2 +Long toe 0.3293842555948132 0.1774637980632155 0.8591440988274508 1.0 1.0 11 Q9UPP1,O14802,Q9Y223 3 +Slender build 0.329094382175145 0.176731993286621 0.8597189094147661 1.0 1.0 11 P04350,O14802,P17612 3 +Vascular calcification 0.3104314584405235 0.1756540551621322 0.8605657326357619 1.0 1.0 6 Q5TBB1 1 +Abnormality of ocular smooth pursuit 0.3623452821774828 0.1756395343455115 0.8605771412191172 1.0 1.0 23 P35251,Q9NW08,O14802,Q9NZJ4 4 +Abnormal blood monovalent inorganic cation concentration 0.3642419738168611 0.1750036532801565 0.8610767629840854 1.0 1.0 24 O00170,P40818,O95163,P08397,Q01968,P50336,Q99996,Q9UNF1,Q9BV10,Q13618 10 +Acute lymphoblastic leukemia 0.3464911923478525 0.1735865033751746 0.862190439729313 1.0 1.0 17 O96017,P49917,P54132,P42771,Q15645,Q08J23,O43683,O43684 8 +Intellectual disability borderline 0.2924500149209237 0.1730057600630525 0.8626469000222536 1.0 1.0 2 Q7Z392 1 +Hyperthyroidism 0.3241095313155321 0.172896454037978 0.862732818947509 1.0 1.0 10 O14802 1 +Palpebral edema 0.3090451598766751 0.1721709616865128 0.8633031261775768 1.0 1.0 6 O00170,Q14331,A6NHR9 3 +Profound hearing impairment 0.304062126642758 0.1699567945994258 0.8650441151447781 1.0 1.0 5 Q9NR77,P35241,P55011,P54577 4 +Squamous cell carcinoma 0.3357799354649775 0.169068719331739 0.8657425890560546 1.0 1.0 14 Q9H4L7,P18074,P42771 3 +Septo optic dysplasia 0.2952238805970192 0.1690078911465987 0.8657904344534855 1.0 1.0 3 Q8WWQ0,Q9BZH6 2 +Single naris 0.2952238805970167 0.1690078911465924 0.8657904344534904 1.0 1.0 3 Q14683,A6NHR9 2 +Truncal obesity 0.34462751695031 0.1689838775964378 0.8658093228369941 1.0 1.0 17 Q06787,Q3SYG4,P40818,P31751,Q8IWS0 5 +Retinal coloboma 0.3188327953572298 0.1686302113670579 0.8660875156225762 1.0 1.0 9 Q15042 1 +Abnormality of the incisor 0.3718489042485542 0.1671308329427331 0.8672671060229697 1.0 1.0 30 Q7Z6Z7,A5YKK6,P42858,Q96N67,Q6W2J9,Q9Y296,Q9BPU6 7 +Neoplasm of the stomach 0.3588655715701041 0.1669748398365566 0.8673898458805218 1.0 1.0 23 O96017,O14965,P52701,P63167,P60866,P20585,P42771,Q9Y620,P11802 9 +Pyridoxine responsive sideroblastic anemia 0.298096597593022 0.165552586306534 0.8685090629109968 1.0 1.0 4 Q9NVI1 1 +Gastrointestinal obstruction 0.3359762470237686 0.1621598137702044 0.871180004854216 1.0 1.0 15 P16930,P42771,P50336,Q01844,P18074 5 +Hyperacusis 0.312156937572668 0.1612995567254348 0.8718574723708234 1.0 1.0 8 O43709,Q13045 2 +Sound sensitivity 0.312156937572668 0.1612995567254348 0.8718574723708234 1.0 1.0 8 O43709,Q13045 2 +Increased laxity of ankles 0.2873769024171931 0.1604517690544748 0.8725252120162101 1.0 1.0 2 Q96C36 1 +Hypointensity of cerebral white matter on mri 0.3041529728114674 0.1602432172478027 0.8726894867890422 1.0 1.0 6 P30566,Q9NZJ7,P22570,Q9Y3Z3,P07602 5 +Diffuse cerebral atrophy 0.3409887335516343 0.1602332198908981 0.8726973617738263 1.0 1.0 17 Q9H269,Q9BTW9 2 +Abnormality of the septum pellucidum 0.3790333784175598 0.1600322928883084 0.87285563598884 1.0 1.0 41 O43505,O60524,Q9ULK4,P28482,Q96C86,Q9BZH6,Q9BV10,Q9NUQ7,Q9UBB6,P48651,Q6DN90,Q08J23,Q96F86,Q14738,Q2M389,Q9NVI1 16 +Abnormal morphology of the olfactory bulb 0.2953120334428138 0.1588330814621314 0.8738003844118334 1.0 1.0 4 Q14683,Q13509,A6NHR9 3 +Melanoma 0.3430643326990027 0.1586106505557425 0.873975637097447 1.0 1.0 18 O96017,P18074,P42771 3 +Fragile nails 0.3212161618343266 0.1575975844602427 0.874773907107818 1.0 1.0 11 O75182,P18074,P26639 3 +Absent toe 0.3591416540419211 0.157493050823623 0.874856284191246 1.0 1.0 25 Q7Z6Z7,P26196,P42858,Q08AM6,Q9Y296,Q9BPU6 6 +Anencephaly 0.3364206853749604 0.1562436317696508 0.8758409858503182 1.0 1.0 16 O43505,Q5TBB1,Q08AM6,Q92917,Q9P2D1 5 +Neoplasm of the eye 0.3361132054354339 0.1555312527608812 0.8764025175707351 1.0 1.0 16 O96017,P52701,P18074,P21359 4 +Ectopia lentis 0.3202430510768292 0.1553353688297834 0.8765569337135883 1.0 1.0 11 Q6W2J9,Q9NZB8,Q03518 3 +Metaphyseal irregularity 0.3267684416510014 0.1551523636501619 0.87670120172692 1.0 1.0 13 P26373,Q5F1R6 2 +Abnormality of the metaphysis 0.358061746844631 0.1538815028275835 0.8777031689836863 1.0 1.0 63 Q06124,Q9Y4X0,P49917,O96017,P26373,Q14999,Q07864,O15357,O00443,Q9HC07,Q99575,Q01968,Q08AM6,A1X283,Q13126,Q5F1R6,Q9P2D1 17 +Pseudobulbar paralysis 0.3080905711244241 0.1518105191208411 0.8793363852436917 1.0 1.0 8 Q14203,P42356,P08397 3 +Hyperorality 0.2961774447409762 0.1511304846865128 0.8798727853811463 1.0 1.0 5 Q14203,Q13501 2 +Abnormality of the diaphragm 0.3633211427935096 0.1503281505935154 0.8805057243827192 1.0 1.0 29 Q92908,P62854,P08243,Q7LBC6,P38935,Q9H3P2,Q9Y4A5,O15111 8 +Mitral valve prolapse 0.357878308741038 0.149980241763343 0.8807802037145667 1.0 1.0 26 Q06124,O43709,P28482,Q9NZJ4,P21359,P46777,A1X283,Q9UBS4,Q6W2J9 9 +Convex nasal ridge 0.3488805327213962 0.1488051602894875 0.881707378655606 1.0 1.0 22 O43933,Q13535,O14802,P28340,P18074 5 +Thick vermilion border 0.2750567302876556 0.1468564976037578 0.8832452894228682 1.0 1.0 87 O00170,O60701,Q93008,P51532,P21359,A1X283,Q4G0J3,Q9NR45,Q14999,O43709,P62081,Q06124,Q9Y4X0,Q96EK5,Q7Z6Z7,Q96N67,P62266,P22681,Q9UID3,Q9BPU6 20 +Long philtrum 0.1859242387431371 0.1459444829619011 0.8839652151905668 1.0 1.0 139 P36507,O15357,Q9Y263,Q93008,A5YKK6,P21359,Q01968,O75909,Q9UET6,Q14999,O43709,P26196,P42858,Q6PGP7,Q9Y296,P27635,P78527,Q7Z6Z7,P42345,O00203,Q00610,Q13555,P28482,P22681,P60953,Q92974,Q6W2J9,Q9Y223,Q9BPU6 29 +Recurrent lower respiratory tract infections 0.3556921488771008 0.1450283980170128 0.8846884504451378 1.0 1.0 26 O95394,Q13432,O00203,Q93008,P50851,P29144,Q00653,P11586,P40763,P09884,Q9BV10,Q9BTW9,P78527 13 +Esophagitis 0.3013211573830988 0.1449538590094228 0.8847473021035495 1.0 1.0 7 O95394,P41252 2 +Abnormalities of placenta or umbilical cord 0.3363333682146507 0.1433448774192364 0.8860178147119828 1.0 1.0 18 O96017,O60826,P26196,P42771,Q9H4L7 5 +Supernumerary spleens 0.3079038802288619 0.143265902613054 0.8860801837721788 1.0 1.0 9 Q86Y56,P57076 2 +Leiomyosarcoma 0.307434669393652 0.1422400737462732 0.8868903793007985 1.0 1.0 9 O96017,O14965,Q9Y620 3 +Focal impaired awareness seizure 0.3476445056346866 0.1410133632951927 0.8878593854500876 1.0 1.0 23 Q05639,P42345,Q08209,O00429,Q00610,Q96N67,Q14204,P67870,Q14353 9 +Shuffling gait 0.3101968210292337 0.1405663006800858 0.888212572009462 1.0 1.0 10 Q9Y3I1 1 +Malrotation of small bowel 0.2872499253508446 0.1404292139967318 0.888320877114154 1.0 1.0 4 Q8NCH0,Q13363,O96028 3 +Hypoplasia of teeth 0.3488232014833216 0.1388409037858674 0.8895758704469976 1.0 1.0 24 O00443,O43933,P21359,Q01968,Q13535,Q5F1R6,P18074 7 +Aplasia hypoplasia affecting the eye 0.1960495162196289 0.1354536343549582 0.8922532207453238 1.0 1.0 101 O75569,O43505,O43709,P26639,Q15042,P10589,P21359,Q08AM6,Q01968,Q96N67,O14802,Q9P2D1,Q6W2J9,P18074,O15111,O60333 16 +Sleep wake cycle disturbance 0.2930982969823695 0.135387523388337 0.8923054882014312 1.0 1.0 6 Q7Z5J4,Q05086,Q8N3U4,Q14683,Q9Y4R8 5 +Abnormal dental root morphology 0.3074708716225677 0.1347659903055931 0.8927968962832393 1.0 1.0 10 Q01968,O43933 2 +Abnormality of toe 0.1790424211824056 0.1336458088816876 0.8936826588408946 1.0 1.0 184 Q3SYG4,Q9UPP1,Q9Y263,Q93008,Q13535,Q9H3P2,Q9P2D1,Q9NVI1,O43709,P26196,P42858,Q5TAQ9,Q9Y296,P27635,Q8IWS0,P49917,O00764,Q7Z6Z7,Q9NZJ4,Q08AM6,Q9H4L7,O14802,Q9BV10,O60333,O60826,P28482,Q15042,P63241,Q6W2J9,Q96C86,Q9BPU6 31 +Abnormal preputium morphology 0.2917497225284653 0.1325543905015797 0.8945458051185977 1.0 1.0 6 Q9NVI1,Q9BXW9 2 +Deviation of the hallux 0.3593196550247887 0.1316189122450109 0.8952857258588238 1.0 1.0 32 O43709,Q7Z6Z7,Q93008,P42858,Q9Y296,Q9BPU6 6 +Short chin 0.3093733708734532 0.1315808719570528 0.8953158159279822 1.0 1.0 11 Q08AM6,P78527 2 +Fetal onset 0.3020968894094926 0.1309355105277541 0.8958263231524601 1.0 1.0 9 P27635,Q9NSD9 2 +Abnormality of the chin 0.3081841142186949 0.130786736852313 0.895944015326815 1.0 1.0 78 Q2VPK5,O00170,Q8IY37,Q01968,A1X283,Q9P2D1,Q14999,O43709,P67870,P27635,P78527,Q06210,Q06124,Q96EK5,Q9BUK6,P42345,Q08AM6,O14802,Q9HCK8,O14646,P28482,Q7LBC6 22 +Hepatocellular carcinoma 0.3402429777402856 0.1301833461988068 0.8964213702539798 1.0 1.0 22 P52701,P16930,P06737,P60866,Q9Y5L0,P08397,P49327,P50336,P54277 9 +Speech apraxia 0.3507349897598815 0.1265696779426827 0.8992809973823763 1.0 1.0 28 O14646,Q7Z6Z7,P26196,P42858,Q9Y296,Q9BPU6 6 +Abnormal lymphocyte morphology 0.3648929722599011 0.1253089014895563 0.9002790053627234 1.0 1.0 43 P31146,Q13432,Q5TBB1,P54132,P49327,Q9P2D1,Q9NRZ9,P98170,O95394,P17812,Q96BN8,Q6PGP7,P49917,O00203,P11586,Q13315,Q9BV10,Q15477,Q6NXR4,P50851,P29144,Q00653,Q14790,Q96Q11 24 +Misalignment of incisors 0.2840110060702799 0.1249971440844309 0.9005258112982037 1.0 1.0 5 Q96N67 1 +Retinal dysplasia 0.2917298592541608 0.1247778408535431 0.9006994307057399 1.0 1.0 7 O43505,O43924 2 +Retinal detachment 0.3211472597396004 0.1235437937808625 0.901676497465176 1.0 1.0 16 O43505,Q13045,P49327,Q8NCH0,Q9BV10,Q6W2J9 6 +Moderate sensorineural hearing impairment 0.2982516447811126 0.123206813401336 0.9019433303645924 1.0 1.0 9 Q93008,Q9UET6,Q92796 3 +Aortic root aneurysm 0.3452176548955392 0.1229074212328879 0.9021804088932432 1.0 1.0 26 O95394,Q06787,Q7Z6Z7,P26196,P42858,Q9UBS4,Q9Y296,Q9BPU6 8 +Hepatic fibrosis 0.353466438999463 0.122380815926981 0.9025974309727508 1.0 1.0 31 Q3SYG4,P06737,O43933,Q9Y5L0,P41252,P35573,Q15477 7 +Atrophic scars 0.2819593787335644 0.1209379949504848 0.9037401474071198 1.0 1.0 5 Q8NCH0,Q96L58,Q02809,Q03001 4 +Elfin facies 0.2894354189331887 0.1202731849412523 0.9042667452098416 1.0 1.0 7 Q9UIG0,O43709 2 +Progressive inability to walk 0.3277925020898406 0.1202589446121006 0.9042780254744556 1.0 1.0 19 Q9H269 1 +Lacrimation abnormality 0.3275636429881577 0.1198183928253854 0.9046270115420044 1.0 1.0 19 O43709,O95163,Q9UIG0,Q01968,Q96IJ6,Q9P2D1,Q10567 7 +Hyposmia 0.3131050976788119 0.1196403113776461 0.9047680851934083 1.0 1.0 14 Q06124,Q96QK1,Q04637,Q9BZH6,P26196,O75165,Q9P2D1 7 +Pes planus 0.297284397436691 0.1193985011449211 0.904959648714599 1.0 1.0 80 Q9Y4X0,Q9UPP1,Q14999,P28482,O43709,P42345,Q93008,P63241,O75909,O95248,Q13535,P53618,Q9P2D1,Q15334,Q06210,Q9HCK8,Q9NVI1 17 +Prominent forehead 0.2894854978287903 0.1193193923457843 0.90502232038246 1.0 1.0 82 Q93008,Q12873,A1X283,Q4G0J3,Q9Y4A5,Q9NR45,P26196,P42858,P40763,Q14204,Q6PGP7,Q9Y296,P78527,Q7Z6Z7,P42345,Q15477,Q12830,Q06787,P29372,P31939,P60953,Q9NSD9,Q9Y223,Q14738,Q9BPU6 25 +Tooth malposition 0.2110535611769344 0.1189375775259275 0.905324810488522 1.0 1.0 98 Q9Y4X0,P28482,O43709,O00170,Q93008,Q15042,Q96N67,Q01968,O43776,A1X283,Q13535,P28340,Q4G0J3,P27635,Q9BTW9,Q6W2J9,Q06210 17 +Abnormal conus terminalis morphology 0.2875074716078831 0.1165835065300337 0.9071901084684476 1.0 1.0 7 P35222,Q13363,Q9H3P2,O60341,O96028,P14868 6 +Genital neoplasm 0.359782679604322 0.1159481115790454 0.907693665279057 1.0 1.0 41 O96017,O14965,P52701,Q07864,Q8IY37,P20585,P42771,P28340,Q01844,P54277 10 +Hepatitis 0.3195673893010741 0.1150313969277516 0.9084202360694812 1.0 1.0 17 P49327,Q15477,Q9Y5L0 3 +Aplasia hypoplasia of the phalanges of the thumb 0.3042275941761997 0.1149648769261066 0.90847296156057 1.0 1.0 12 Q08AM6,A5YKK6 2 +Supravalvular aortic stenosis 0.2826411711980793 0.1145456851296387 0.908805233196928 1.0 1.0 6 P78347,O43709,Q9UIG0,Q9Y4P3,P35250 5 +Nystagmus induced head nodding 0.2826411711980793 0.1145456851296387 0.908805233196928 1.0 1.0 6 P78347,O43709,Q9UIG0,Q9Y4P3,P35250 5 +Phonophobia 0.2826411711980793 0.1145456851296387 0.908805233196928 1.0 1.0 6 P78347,O43709,Q9UIG0,Q9Y4P3,P35250 5 +Overfriendliness 0.2826411711980793 0.1145456851296387 0.908805233196928 1.0 1.0 6 P78347,O43709,Q9UIG0,Q9Y4P3,P35250 5 +Flat cornea 0.2826411711980793 0.1145456851296387 0.908805233196928 1.0 1.0 6 P78347,O43709,Q9UIG0,Q9Y4P3,P35250 5 +Dolichocephaly 0.355261207157075 0.1139740386565659 0.9092583734659232 1.0 1.0 36 Q92908,Q14999,O15357,O43933,P54132,P42356,Q08AM6,Q9H3P2,P27635,Q14738,Q9NVI1 11 +Leukopenia 0.3593098404714371 0.1137440873391398 0.9094406626455612 1.0 1.0 48 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61254,P61313,P62899,P40763,Q5F1R6,Q6W2J9,Q9NVI1 15 +Renal dysplasia 0.3065962362526349 0.1133443642342124 0.9097575462616848 1.0 1.0 13 Q9Y4X0,Q93008 2 +Abnormal cerebellar vermis morphology 0.2790797660439516 0.1119563753904907 0.910857996429528 1.0 1.0 84 O60826,O43505,Q9NZJ4,Q93008,Q9Y4A5,P42858,Q15042,P42356,Q6W2J9,Q13535,O14802,Q9UID3,Q9P2D1,Q15334,Q9BPU6,P78527 16 +Pointed chin 0.3507882302404189 0.1118275458878417 0.9109601460480246 1.0 1.0 33 Q96EK5,Q14999,O43709,O14646,P28482,Q8IY37,O14802,Q7LBC6,Q9HCK8 9 +Aplasia hypoplasia involving forearm bones 0.3274723806942125 0.1101599188588916 0.9122825488730144 1.0 1.0 21 Q14999,P61254,Q13535,Q9BV10,Q9P2D1 5 +Rib fusion 0.2875934230194414 0.1099199825566671 0.9124728347829676 1.0 1.0 8 Q6DKJ4,P18583,Q13363,Q96T58,Q9H3P2,O43318,O96028 7 +Lissencephaly 0.3512203651193111 0.1082544137539405 0.9137938825875904 1.0 1.0 56 P57081,Q96EK5,Q2VPK5,O43505,Q15042,P42356,Q08AM6,Q00535,O43776,Q13535,Q14204,Q00534,Q9BV10,P78527,P42695 15 +Bladder diverticulum 0.2827256425582723 0.1078059337203347 0.9141496358979424 1.0 1.0 7 P78347,O43709,Q9UIG0,Q9Y4P3,Q02809,P35250 6 +Macule 0.3344461439578681 0.1072859626028204 0.9145621204838288 1.0 1.0 66 Q06124,P52701,P28482,Q7Z6Z7,P42345,P26196,P42858,P21359,Q9H4L7,P53618,A1X283,Q6PGP7,Q13315,Q9Y296,Q9BPU6,P18074,Q15477,O60333 18 +Abnormality of hair pigmentation 0.3281180110910726 0.1070102790874949 0.9147808250505098 1.0 1.0 22 O14617,P49327,Q6PGP7,Q13315,Q13126,Q15477 6 +Abnormal hair whorl 0.3303690002302228 0.1069018690191561 0.9148668304270346 1.0 1.0 23 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Unsteady gait 0.3490975667885578 0.1061556563722233 0.9154588531661824 1.0 1.0 57 Q16512,O75569,Q05639,O60231,Q9NZJ4,Q8NC96,P42858,Q00610,Q08AM6,P49770,Q13144,Q12873,Q7Z460,Q69YN2,Q96F07,Q96C86,Q14738 17 +Bradykinesia 0.3297575072766536 0.1058222351540179 0.9157233947417992 1.0 1.0 23 O75569,P42858,Q9Y3I1 3 +Keratitis 0.2989431233477459 0.1054597991988625 0.9160109676474436 1.0 1.0 12 P49327,P18074,P26639 3 +Unusual infection 0.1752965887712279 0.1043517101475324 0.9168902431038896 1.0 1.0 207 Q9NPL8,O15357,Q93008,P51532,Q01968,P49327,Q9H3P2,Q86Y56,Q5F1R6,Q9NVI1,Q9NRZ9,O43709,P14174,P17812,P26196,O95163,P41252,Q9Y5L0,P40763,Q6PGP7,Q9UBS4,P27635,P78527,P18074,Q92908,P49917,Q07864,P26639,O00203,O14802,Q13315,Q9BV10,Q9UDY8,Q15477,O60826,P57076,Q06787,O14617,P28482,P50851,P40818,P29144,Q9UID3,Q9BTW9,Q6W2J9 45 +Dyslexia 0.2879998797854629 0.1042815596565386 0.9169459113820722 1.0 1.0 9 Q13501 1 +Upper extremity joint dislocation 0.3281643582537802 0.1030496783401799 0.9179235431755436 1.0 1.0 23 Q13535 1 +Hydrops fetalis 0.3541280834942771 0.1027998290892879 0.918121840914212 1.0 1.0 45 P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,P61313,P62899,P49327,Q08AM6 12 +Renal duplication 0.2822122571001592 0.1005440520320312 0.9199124115363884 1.0 1.0 8 P78347,O43709,Q15056,Q9UIG0,Q9Y4P3,P35250,Q9BXW9 7 +Abnormal circulating aspartate family amino acid concentration 0.2844874509236758 0.0983514470902705 0.9216532272941622 1.0 1.0 9 Q99707 1 +Irregular hyperpigmentation 0.3210884991635124 0.0979984278082659 0.9219335417870432 1.0 1.0 70 Q06124,P52701,P28482,Q7Z6Z7,P42345,P26196,P42858,P21359,Q9H4L7,P53618,A1X283,Q6PGP7,Q13315,Q9Y296,Q9BPU6,P18074,Q15477,O60333 18 +Gonadal dysgenesis 0.2941877411430608 0.0974476993092259 0.9223708663742032 1.0 1.0 12 Q8IY37,P18074 2 +Impaired vibratory sensation 0.3364252676153381 0.0968654351471164 0.9228332584433104 1.0 1.0 29 Q5TAQ9,Q9Y6B6,Q9NZJ4 3 +External ophthalmoplegia 0.3109151961101521 0.0952315174215362 0.924130936459308 1.0 1.0 18 P26640,Q8NCE2,O95352 3 +Low anterior hairline 0.343788718292503 0.0951953693076725 0.9241596480419972 1.0 1.0 57 Q9NR45,P49917,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,O00443,P61313,P51532,Q96N67,P61254,P62899 16 +Functional abnormality of male internal genitalia 0.3400267560315454 0.0950888478627503 0.9242442560536168 1.0 1.0 32 P57076,O43709,Q9BZH6,O00170,Q8IY37,P54132,Q01968,Q9UBS4,Q13315,Q86Y56,Q9P2D1,Q9NVI1 12 +Aplasia hypoplasia of the optic nerve 0.3204264109524607 0.0940643094599871 0.9250580715608852 1.0 1.0 22 P36507,Q96KP1,Q15058,P10589,O14802,Q9NVI1 6 +Abnormality of earlobe 0.3324540607491481 0.0932312726456871 0.9257198305999428 1.0 1.0 28 P53992,P28482,O60701,P46109,Q96N67,Q99741,Q5VIR6,Q13535,O14802,Q9P2D1,Q8IWS0 11 +Eclabion 0.3433000628213397 0.0924408200889069 0.92634780851197 1.0 1.0 36 Q96EK5,Q14999,Q15042,Q96N67,Q01968,P46821,P27635,P18074 8 +Generalized hypotonia 0.1740970765592132 0.0922465567759357 0.9265021487478808 1.0 1.0 371 P00374,O75880,Q2VPK5,O15357,Q93008,A5YKK6,O60701,O43772,O43933,P51532,Q7KZN9,O43776,Q13144,Q12873,Q9Y4A5,Q9Y6D5,Q9H1B7,Q9NR45,Q9ULK4,Q9UPN3,Q14839,P27708,P41252,Q96IJ6,Q96F07,P27635,P26640,P67870,O00217,P18074,Q8IWS0,Q96F86,Q06210,Q9Y4X0,Q96EK5,Q9BUK6,O60524,Q7Z6Z7,P26639,P42345,P50570,Q00610,P50747,O14802,Q69YN2,Q9BV10,Q16512,O60826,O14617,O60231,O14646,P62266,P28482,Q13555,P22681,Q99707,Q9C0E8,Q9HC07,P31939,Q99986,Q7Z460,Q6W2J9,Q9UID3,Q2M389,Q96C86,Q7LBC6,Q8NCE2 67 +Abnormal intraocular pressure 0.2655316606929405 0.0919904413280783 0.9267056341049232 1.0 1.0 5 Q8NCH0,P04439,Q12797,O75533 4 +Mild hearing impairment 0.2906078027298633 0.0917490203579978 0.9268974489953704 1.0 1.0 12 Q92796,Q93008,Q9UET6,O95394 4 +High hypermetropia 0.2829793598564138 0.0903773051749216 0.9279873907242212 1.0 1.0 10 Q7Z5J4,P78347,O15294,O43709,Q9UIG0,Q9Y4P3,Q96T58,P35250,P68371 9 +Recurrent bacterial infections 0.3177859410515165 0.0899255947349534 0.9283463418904314 1.0 1.0 22 Q92908,P57076,O00203,P40763,Q5F1R6,Q86Y56,Q9UDY8 7 +Abnormality of the curvature of the cornea 0.3005605558903724 0.0898834491434272 0.9283798335796358 1.0 1.0 76 Q3SYG4,Q93008,P10589,Q12873,Q5F1R6,Q9NVI1,O43709,P26196,Q14839,P42858,P61586,Q92620,Q9Y296,P26640,Q10567,P18074,Q7Z6Z7,P26639,Q9UIG0,Q8NCH0,Q12830,Q92974,Q14738,Q9BPU6,Q6P2Q9 25 +Smooth philtrum 0.3093584789916723 0.0894778132051053 0.9287021853444024 1.0 1.0 73 Q9Y263,Q15436,O60701,Q93008,O95352,Q9Y4A5,P26196,P42858,Q9Y296,P27635,P67870,Q7Z6Z7,P42345,O00203,O14617,P28482,P29372,P60953,Q9Y223,Q9BPU6 20 +Fibrous tissue neoplasm 0.3070595749080351 0.089213053592516 0.9289125914781478 1.0 1.0 18 P52701,Q13126,P21359 3 +Pterygium 0.2855707671674219 0.0891247166416222 0.9289827945165368 1.0 1.0 11 P18074 1 +Bradycardia 0.2888528313443429 0.089058439659013 0.9290354664456448 1.0 1.0 12 O75880 1 +Abnormality of vitamin metabolism 0.3278221928308585 0.0888582832013666 0.929194537534118 1.0 1.0 27 Q99707,P49327,Q01968,Q5F1R6,Q9Y6B6 5 +Melanocytic nevus 0.2880289984745127 0.0878185731692665 0.9300208755431244 1.0 1.0 12 Q06124,P18074 2 +Progressive extrapyramidal movement disorder 0.2621991883881637 0.0868726650842971 0.9307727274591155 1.0 1.0 5 Q14353 1 +Hammertoe 0.3132450510484196 0.0867276625693627 0.9308879877072592 1.0 1.0 21 Q5TAQ9,O00764,O60333,Q9NZJ4 4 +Abnormal right atrium morphology 0.2579874589429609 0.0866286211257529 0.9309667150465826 1.0 1.0 4 Q92908,Q14315,Q7L590 3 +Abnormality of corneal thickness 0.2996256536867575 0.0865839132945896 0.931002253205014 1.0 1.0 16 P10589,O43395,Q92620,Q10567,Q6P2Q9,P20839 6 +Obsessive compulsive behavior 0.3443884380096246 0.0858927978473308 0.9315516368383574 1.0 1.0 44 Q9H269,O75182,P28482,Q93008,P42858,P10589,Q01968,P46821,Q9P2D1,Q13501,Q9Y4A5 11 +Colpocephaly 0.2728478857754173 0.0857855563857415 0.9316368884829284 1.0 1.0 8 Q8IY37,Q86XI2,Q9NVI1 3 +Autoimmunity 0.3379342179127577 0.0855947764010113 0.9317885510493328 1.0 1.0 35 P49917,Q969U7,Q06787,P53621,P14174,Q5TBB1,P50851,P29144,Q9Y5L0,P49327,P40763,Q9P2D1,Q9Y3Z3 13 +Short foot 0.331865295702339 0.0845206460438865 0.932642488403706 1.0 1.0 31 P49917,Q13555,Q7Z6Z7,O15357,Q93008,P42858,Q9Y4A5 7 +Recurrent otitis media 0.330005849469682 0.0841108967153818 0.9329682610208518 1.0 1.0 30 Q12830,P57076,Q06787,P28482,O00203,Q9H7D7,P50851,P29144,Q00653,O14802,Q86Y56,Q6W2J9 12 +Abnormal uvula morphology 0.3432846902069871 0.0841052106407074 0.9329727818332472 1.0 1.0 44 P18583,Q15436,Q93008,P48651,Q9BXW9,A6NHR9,Q9NVI1,Q15058,Q6PGP7,P46777,Q92796,Q99741,Q9Y4X0,O43505,P09884,P78318,P62266,Q6W2J9,Q13618 19 +Bifid uvula 0.3402476963499409 0.0832984979692191 0.9336141945924814 1.0 1.0 39 Q9Y4X0,O43505,Q15058,P18583,P62266,Q15436,Q13618,Q93008,P78318,P48651,Q6PGP7,P46777,P09884,Q6W2J9,Q92796,A6NHR9,Q99741 17 +Decreased fertility 0.3276394561729999 0.0831008987749666 0.9337713112009044 1.0 1.0 29 Q06124,Q14999,O00170,Q8IY37,P40818,Q96RD7,Q86Y56,Q9P2D1,Q9NVI1 9 +Areflexia of lower limbs 0.3129324123684355 0.0827160061316606 0.9340773574349917 1.0 1.0 22 Q9NZJ4,P50570,Q9Y223,Q13501,Q8NCE2 5 +Agenesis of corpus callosum 0.2523637969704705 0.0826352829407368 0.9341415454763726 1.0 1.0 88 P57081,O43505,O60231,Q9H3P2,P29372,P26639,A5YKK6,Q15042,P51532,Q08AM6,Q00535,O14802,Q69YN2,Q00534,Q9BPU6,P18074,P42695 17 +Polymicrogyria 0.29041438571974 0.0811855791650634 0.93529436781582 1.0 1.0 78 Q8IY37,O43933,P42356,Q9Y4A5,Q9ULK4,Q14204,P67870,Q96F86,Q96EK5,O43505,O60524,P42345,Q9UBB6,Q00610,O14802,Q15042,P46821,Q96C86,Q2M389 19 +Aplasia hypoplasia of the humerus 0.2765488259991386 0.0809543264867553 0.9354782754116178 1.0 1.0 10 O14802 1 +Short long bone 0.3386696417049873 0.0808939181539946 0.9355263167254456 1.0 1.0 39 Q9Y4X0,P26373,Q14999,O15357,P61254,A1X283,Q13535,O14802,Q9BV10,Q9P2D1 10 +Small face 0.3409365164671656 0.080066493333388 0.9361843716100822 1.0 1.0 45 P04350,P36507,P49917,Q12830,Q06787,O43709,Q7Z6Z7,P26196,P42858,P54132,Q6W2J9,Q13535,Q9Y296,Q08J23,Q9P2D1,Q9BPU6 16 +Abnormality of skin physiology 0.184872762317711 0.0797467628749627 0.936438666462978 1.0 1.0 101 P49917,Q07864,P26639,P22681,O00170,P50851,P14174,O00203,Q9Y5L0,P50747,P49327,Q9H4L7,Q96BN8,A1X283,O14802,Q5F1R6,Q9P2D1,P18074 18 +Hypotension 0.3196508724864459 0.079725446619883 0.9364556203928038 1.0 1.0 26 Q06787,Q04637,P22681,O00170,O95163,O43772,Q9Y5L0,Q96IJ6,O75165,Q9UER7 10 +Hernia 0.1752955324193504 0.0797169949914679 0.9364623424218173 1.0 1.0 135 P51532,Q01968,A1X283,Q5F1R6,Q9H3P2,Q9P2D1,Q9Y4A5,Q9Y6D5,Q9NVI1,P57081,O43709,P26196,Q6PGP7,P27635,P18074,P26639,P42345,P62854,O15111,Q15477,O60826,P28482,Q6W2J9,P46821,Q7LBC6 25 +Abnormal forearm bone morphology 0.3104950308732764 0.0792864690285811 0.9368047685696596 1.0 1.0 22 Q14999,P61254,Q13535,Q9BV10,Q9P2D1 5 +Abnormality of the scrotum 0.3403620259621871 0.0790795374963088 0.9369693592469664 1.0 1.0 48 Q96EK5,Q7Z6Z7,Q8IY37,P26196,Q9BPU6,P42858,Q9Y296,Q9P2D1,Q9Y4A5,P18074,Q8IWS0 11 +Broad thumb 0.3290181054572761 0.0781975953128189 0.9376708748245082 1.0 1.0 32 P49917,Q7Z6Z7,Q93008,P26196,P42858,Q9Y296,Q9BPU6 7 +Dental malocclusion 0.3204745472571424 0.0781172822648977 0.9377347599433252 1.0 1.0 27 O43709,A1X283,Q13535,Q6W2J9,Q06210 5 +Abnormality of the clitoris 0.3184857734480617 0.078106074709895 0.9377436750394614 1.0 1.0 26 Q08AM6,Q8IY37,Q13535,Q15042 4 +Abnormal morphology of the radius 0.2875702168717882 0.0780788885887767 0.9377653003847448 1.0 1.0 14 Q9BV10,Q13535,P61254 3 +Small nail 0.3388242889467931 0.0779802300946435 0.9378437791964194 1.0 1.0 51 P49917,O60826,O43709,Q7Z6Z7,O15357,Q8IY37,Q99575,P63241,Q9H4L7,O14802,Q5F1R6,Q9BV10,Q9Y4A5,P18074 14 +Disproportionate tall stature 0.3239520097967275 0.0778367571552842 0.937957907150289 1.0 1.0 29 Q7Z6Z7,P26196,P42858,Q9Y296,Q15334,Q9BPU6 6 +Slender long bone 0.2900064776686639 0.077234616279357 0.9384369040725662 1.0 1.0 15 Q08AM6,Q14999 2 +Abnormal nipple morphology 0.3282384826671644 0.0760617302093642 0.9393699867728728 1.0 1.0 61 Q06124,Q9Y4X0,Q96EK5,O60826,P26639,P22681,Q93008,P26196,Q92974,P21359,Q08AM6,Q5SRE5,Q9H3P2,Q9BV10,Q9P2D1,Q9Y4A5,P18074 17 +Abnormal shape of the palpebral fissure 0.2762277254762598 0.0758996719262177 0.9394989178732198 1.0 1.0 11 P28482,O14646 2 +Submucous cleft of soft and hard palate 0.3122419819384646 0.0754049517993459 0.9398925194626992 1.0 1.0 24 P36507,Q9Y4X0,P49917,O43505,P49589,P62266,P48651,Q08J23,Q14738,Q6W2J9,Q13618,Q99741 12 +Aplasia hypoplasia of the radius 0.2967012668768944 0.0746263094453029 0.9405120405757036 1.0 1.0 18 Q9BV10,Q9P2D1,Q13535,P61254 4 +Primary microcephaly 0.2938826236427058 0.0746078747068916 0.9405267084786562 1.0 1.0 17 Q08AM6,Q9BTW9,Q5SRE5 3 +Astigmatism 0.3348688415216461 0.0744521407166285 0.9406506215951352 1.0 1.0 54 Q3SYG4,Q7Z6Z7,P26639,Q93008,P26196,Q14839,P42858,Q9BPU6,Q12873,Q5F1R6,P26640,P18074,Q9Y296 13 +Prominent nose 0.315658946156688 0.0742967980074606 0.9407742248116904 1.0 1.0 26 P49917,Q12830,Q6NXR4,Q93008,P54132,Q12873,Q13535,P56589,Q08J23,Q13620 10 +Telangiectasia of the skin 0.3088679568213648 0.0739481382596145 0.941051651880705 1.0 1.0 23 P49917,Q07864,P21359,Q13315,Q9UER7,P18074 6 +Abnormal peripheral myelination 0.3306343325588674 0.0733776906609002 0.9415055700032507 1.0 1.0 36 O60231,Q9NZJ4,P50570,Q13614,Q5TAQ9,O95248,P26358,O60333 8 +Joint contracture of the hand 0.3358134291844738 0.0733095703317298 0.9415597761706213 1.0 1.0 51 P57081,P28482,O43933,Q15042,Q01968,Q9H4L7,P38935,A1X283,O14802,P27635,Q6W2J9,P18074 12 +Inverted nipples 0.2633418802138273 0.0727567548536076 0.9419996843336902 1.0 1.0 8 Q9BV10,P56589 2 +Broad toe 0.3196884073128622 0.072115739488595 0.9425098005385264 1.0 1.0 29 O60826,Q7Z6Z7,Q93008,P42858,Q6W2J9,Q9Y296,Q9BPU6 7 +Abnormality of the musculature of the lower limbs 0.3113425114745297 0.0714135024426442 0.9430686636520916 1.0 1.0 25 O60231,Q9NZJ4,Q14204,Q96IJ6,Q8NCE2 5 +Periorbital fullness 0.3041994218424724 0.0710035348028954 0.9433949422277306 1.0 1.0 22 P57081,Q9UET6,O14646,P62266,Q93008,Q96N67 6 +Dilation of lateral ventricles 0.3038324506373124 0.0705458096095827 0.943759240550852 1.0 1.0 22 Q05639,Q15042,Q00610,Q14204,Q9UID3,P67870,Q14738 7 +Partial agenesis of the corpus callosum 0.2846279360699825 0.070338920818726 0.9439239048727336 1.0 1.0 15 P57081,P18074 2 +Poikilocytosis 0.2874423098165531 0.070134086800649 0.944086936146442 1.0 1.0 16 Q9Y6B6 1 +Increased circulating antibody level 0.2927428215184571 0.069640287541968 0.944479969942581 1.0 1.0 18 P49917,O95394,P29144,Q9NRW7,Q9Y5L0,P49327,Q96BN8,P40763 8 +Arrhinencephaly 0.2777573318870511 0.0695428646448622 0.944557514167636 1.0 1.0 13 Q08AM6,Q5TBB1,Q9P2D1 3 +Abnormality of the ovary 0.3158610778857869 0.0694048509786545 0.9446673677103576 1.0 1.0 66 Q06124,O96017,P52701,Q3SYG4,O43709,O00170,Q8IY37,P31751,P20585,P49327,P42771,Q13144,Q01844,Q13315,Q9P2D1,P54277 16 +Gastrointestinal inflammation 0.3019672750820684 0.0682612494752701 0.945577670585328 1.0 1.0 22 P50851,P41252,Q9Y5L0,P49327,Q15477 5 +Recurrent hand flapping 0.2459832201186557 0.065410399607807 0.9478472441240636 1.0 1.0 5 Q06787 1 +Abnormal shape of the occiput 0.3189424623979237 0.0650831603136315 0.9481077881263112 1.0 1.0 32 O60826,P62266,A5YKK6,O43933,Q01968,A1X283 6 +Abnormal heart valve morphology 0.2655731689066287 0.0650719950834774 0.948116677846736 1.0 1.0 83 P21359,A1X283,Q9H3P2,Q9P2D1,Q9UER7,Q9Y6D5,Q9NVI1,O43709,Q6PGP7,P46777,Q9UBS4,Q92908,Q9Y4X0,Q06124,Q9NZJ4,O14802,Q15477,O60826,Q06787,P28482,P22681,P61254,P46821,Q6W2J9 24 +Papilledema 0.2963904126189122 0.0646044690615305 0.9484889263494196 1.0 1.0 21 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Abnormal blood phosphate concentration 0.2632131354561019 0.0641757047625997 0.9488303222990468 1.0 1.0 10 Q01968,O15357 2 +Benign neoplasm of the central nervous system 0.3007400454988336 0.0640404849923483 0.9489379905883396 1.0 1.0 23 O96017,Q9H269,P52701,P21359,Q01968,P54277,O60333 7 +Progressive spasticity 0.2787455855866436 0.0634594695919296 0.9494006327409804 1.0 1.0 15 Q9BTW9 1 +Low frustration tolerance 0.2587113944373152 0.0630341333600312 0.9497393238641414 1.0 1.0 9 O75165,Q14738,Q04637 3 +Abnormal ovarian morphology 0.3134201636035239 0.0623822080480773 0.9502584632822992 1.0 1.0 30 Q3SYG4,O43709,Q8IY37,P31751,P20585,Q13315,Q9P2D1 7 +Congenital diaphragmatic hernia 0.3013303099470766 0.0621290179007361 0.9504600886864638 1.0 1.0 24 P62854,Q7LBC6,Q9H3P2,Q9Y4A5,O15111 5 +Sparse scalp hair 0.3230657867092376 0.0612454042003219 0.9511637702544228 1.0 1.0 38 P49917,Q96EK5,P26639,P63241,P49327,Q01968,Q08AM6,Q13535,O14802,P46778,P18074 11 +Tall stature 0.325671891941838 0.0611405397195464 0.9512472834971024 1.0 1.0 54 P04350,Q7Z6Z7,O00170,A5YKK6,P42858,P21359,O14802,Q9Y296,Q15334,Q9BPU6,Q9HCK8 11 +Shyness 0.2380248042557952 0.060985793419521 0.9513705232037162 1.0 1.0 4 Q06787 1 +High forehead 0.2116312124637053 0.0609127761024171 0.951428674482689 1.0 1.0 95 O43933,A1X283,Q9H3P2,P57081,O43709,P26196,P42858,Q9Y296,Q96F07,Q06124,Q7Z6Z7,P42345,Q00610,Q08AM6,Q05639,Q13555,P28482,P22681,Q8NC96,Q9BPU6 20 +Abnormal vena cava morphology 0.255835009368637 0.0599347048806056 0.9522076390692852 1.0 1.0 9 Q86Y56,Q7LBC6 2 +Fetal ultrasound soft marker 0.2919258130786658 0.0596958979664349 0.952397838859047 1.0 1.0 21 Q06124,O60826,P22681,P26196,O43933,Q13501,Q9BPU6 7 +Spastic gait 0.2966861692370416 0.0595836713599451 0.952487223627672 1.0 1.0 23 Q9NZJ4,Q9Y3I1 2 +Contractures of the joints of the upper limbs 0.2854321220489566 0.0588029945228734 0.9531090233057936 1.0 1.0 76 O60231,P28482,O00443,O43933,Q15042,Q01968,Q9H4L7,A1X283,P38935,Q13535,O14802,P27635,Q6W2J9,P18074 14 +Neoplasm of the nervous system 0.3254261168390989 0.0584960624810797 0.9533534988110006 1.0 1.0 49 Q06124,Q9H269,P52701,O96017,Q07864,P20585,P42771,Q01968,P21359,P28340,Q01844,Q9UER7,P54277,O60333 14 +Blue irides 0.2578713271926808 0.0584440472137286 0.9533949301076096 1.0 1.0 10 P28482,Q9UIG0,O43709 3 +Facial asymmetry 0.3170792957065409 0.0582228532513211 0.9535711173354522 1.0 1.0 35 Q9UPN3,P28482,Q8IY37,Q93008,P46109,P21359,Q13535,P61586,Q9P2D1,Q14738,Q9NVI1 11 +Decreased facial expression 0.2971557306823411 0.0576660777224613 0.954014614767879 1.0 1.0 24 O75165,Q9Y3I1,Q9Y263 3 +Abnormal talus morphology 0.289969508946988 0.0576632962083209 0.9540168304082616 1.0 1.0 21 Q14999,Q9Y263,O43933,Q08AM6,P18074 5 +Abnormality of the pylorus 0.319447933822406 0.0571585062690183 0.9544189312920952 1.0 1.0 38 P28482,P50570,Q93008,O43933,Q08AM6,Q8NCE2,P46821,Q6W2J9,Q9Y6D5 9 +Hamartoma 0.2841980897620181 0.0571090560484609 0.9544583225153338 1.0 1.0 19 Q9H269,P52701,P20585,P21359 4 +Truncal ataxia 0.2861116044146445 0.056365444385279 0.9550506845583372 1.0 1.0 20 O14802,Q9NZJ4 2 +Abnormality of the small intestine 0.3214242550210016 0.0557436520025971 0.955546024274388 1.0 1.0 54 Q9UET6,P50851,Q93008,O00443,Q9Y5L0,Q6PGP7,Q5F1R6,Q9P2D1,Q7LBC6,Q9Y6B6,Q15477,Q9NVI1 12 +Abnormal morphology of the musculature of the neck 0.2741329861269556 0.0555410495656248 0.9557074275789976 1.0 1.0 16 Q9H269,O75569 2 +Abnormality of the pituitary gland 0.3079581669121549 0.0545969358079136 0.9564595799905012 1.0 1.0 65 O00170,Q8IY37,P42356,Q5F1R6,Q9P2D1,Q9NVI1,P57081,Q14746,P52701,Q9UBS4,Q96IJ6,O14654,Q92908,Q9BUK6,Q07864,P60866,O14802,P40818,P54277 19 +Embryonal renal neoplasm 0.2606475267744829 0.0545617803696896 0.956487588223852 1.0 1.0 12 Q8IY37,Q9UPY3,P54132,Q15645,O43683,O43684 6 +Abnormal pons morphology 0.2932700858769554 0.0538024406544464 0.95709256497702 1.0 1.0 24 Q9NZJ4,P08243,Q96N67,Q99986,Q9UID3 5 +Excessive salivation 0.3032163058397303 0.0534859301510062 0.9573447407159436 1.0 1.0 29 P42356,Q9NW08,Q08AM6,O14802 4 +Abnormal morphology of the abdominal musculature 0.2513309730522847 0.0521466207285176 0.9584118655044068 1.0 1.0 10 Q06124,P42345 2 +Abnormal circulating androgen level 0.2644336821601163 0.0521373588566126 0.9584192453700404 1.0 1.0 14 Q8IY37,O14802 2 +Hypoplastic female external genitalia 0.273179196397445 0.0519087805092033 0.9586013778754588 1.0 1.0 17 Q08AM6,Q15042 2 +Abnormal size of the clitoris 0.2859436610071206 0.0513836894373989 0.9590197815465182 1.0 1.0 22 Q08AM6,Q8IY37,Q13535 3 +Intestinal atresia 0.2567553950752968 0.0509949198609989 0.9593295686467648 1.0 1.0 12 P18583,Q15645,Q9P2D1,Q7LBC6,O43683,O43684 6 +Broad long bones 0.3140920413853121 0.0506446258368792 0.9596087021541152 1.0 1.0 39 Q9Y4X0,P49917,Q7Z6Z7,Q93008,P26196,P42858,Q9Y296,Q9BPU6 8 +Exodeviation 0.2895274441716052 0.0503360864277969 0.9598545673950468 1.0 1.0 24 Q6XZF7,P10589 2 +Abnormal eating behavior 0.2846705350054602 0.050242388126295 0.9599292333480683 1.0 1.0 22 Q3SYG4 1 +Recurrent pneumonia 0.2833527582787578 0.0490901934332769 0.9608474184930662 1.0 1.0 22 O95394,Q13432,O00203,P50851,Q00653,P11586,P40763,P09884,Q9BV10,Q9BTW9 10 +Blepharophimosis 0.3165170275161647 0.048659066193031 0.961190997655156 1.0 1.0 50 P49917,O43709,Q7Z6Z7,P28482,P26196,P42858,Q6W2J9,Q13535,Q92917,Q9Y296,Q9BPU6,Q8IWS0 12 +Emg myopathic abnormalities 0.2996538452325543 0.0485150300591407 0.9613057862916524 1.0 1.0 30 Q9BUK6,O60231,Q9Y5L0,Q13501,Q8NCE2,Q9Y6B6 6 +Abnormality of the peritoneum 0.2774005921077609 0.0483670343705767 0.961423731304337 1.0 1.0 20 Q9P2R3,Q01844,Q9Y5K6,P42771 4 +Pancytopenia 0.3104979772655665 0.0481675471894322 0.9615827137448938 1.0 1.0 38 P00374,P49917,P22681,P50851,O76094,Q13535,Q5F1R6,Q6W2J9 8 +Abnormal facial expression 0.3009445477947828 0.0481334568553602 0.9616098823830116 1.0 1.0 31 Q9BUK6,Q06787,O94903,Q04637,Q9Y263,P50570,O75165,Q8NCE2,Q9Y3I1 9 +Secondary microcephaly 0.275790870320407 0.0481194483321183 0.9616210466308696 1.0 1.0 77 P00374,P47897,Q05639,Q14746,O94903,Q9Y263,P26640,Q8N8R5,P60953,Q9HC07,P08243,Q00610,Q9BSJ2,Q13144,Q9BV10,Q9BTW9,Q9Y6D5,Q01433 18 +Memory impairment 0.3086766674111326 0.0474970962635376 0.9621170445716518 1.0 1.0 37 P52701,Q06787,P60866,P42858,P21359,P49327,Q13144,P26358,Q9Y223,Q13501,P54277 11 +Overlapping toe 0.2814441980372924 0.0474731639535725 0.9621361182760976 1.0 1.0 22 O60826,P28482,Q7Z6Z7,Q93008,Q15042 5 +Impaired proprioception 0.3106589093408712 0.0474084770338806 0.962187672922687 1.0 1.0 39 Q5TAQ9,O14802,Q9Y6B6,Q9NZJ4 4 +Small hand 0.3046292049440342 0.0472946615150164 0.962278382817342 1.0 1.0 34 Q96EK5,Q7Z6Z7,Q93008,P42858,Q14204,O15111 6 +Neoplasm of the skin 0.3118176898823483 0.0469070818123225 0.9625872838389208 1.0 1.0 41 P52701,P26639,P60866,P20585,P42771,P49327,Q01968,P21359,Q9H4L7,P18074,P54277 11 +Abnormal cerebral artery morphology 0.261098759882677 0.0466657344175347 0.9627796405519486 1.0 1.0 15 Q5TBB1,Q9Y3Z3,Q9UBS4,P21359 4 +Abnormal delivery 0.2798608718406931 0.046177319924699 0.9631689192654648 1.0 1.0 22 Q7LBC6,Q8NCE2,O14802 3 +Neoplasm of the pancreas 0.2866654706401843 0.0459755843387661 0.9633297102012 1.0 1.0 25 O96017,P54277,Q01844,P42771 4 +Dyskinesia 0.2992494226041686 0.0457643845204287 0.9634980460879748 1.0 1.0 66 O75569,O95352,O75165,P52701,Q9ULK4,Q14204,Q96F07,Q96F86,P67870,O00217,O60524,P60866,Q9UBB6,Q00610,Q05639,Q04637,Q96C86,Q2M389,P54277 19 +Telangiectasia 0.3054910928438693 0.0457408684953245 0.9635167895332128 1.0 1.0 36 P49917,Q07864,P21359,Q13535,P28340,Q13315,Q9UER7,P18074 8 +Plagiocephaly 0.3051075934873843 0.0454131565831807 0.963777994370487 1.0 1.0 36 Q14738,P28482,Q9BTW9,Q9BV10,Q8IY37,O60701,Q5TBB1,P63241,Q14204,Q96F07,Q9Y3Z3,Q9BPU6 12 +Gastroesophageal reflux 0.1657335852227832 0.0449540018964414 0.9641439730291748 1.0 1.0 128 Q15436,Q93008,P42356,Q01968,Q9P2D1,Q9Y6D5,O95394,O43709,O95163,Q14204,Q96F07,P67870,P27635,P57678,O00203,Q00610,Q9BV10,Q16512,Q05639,O60826,Q06787,P28482,P29372,Q8NC96,P63241,P46821,Q86TI2 27 +Postaxial polydactyly 0.2754415248408805 0.0446821713934647 0.9643606446707498 1.0 1.0 21 Q92908,Q2VPK5,Q3SYG4,P17612,Q9Y263,Q93008 6 +Resting tremor 0.2637323515165469 0.0440967286700861 0.9648273003931098 1.0 1.0 17 P26358 1 +Aplasia hypoplasia of the eyebrow 0.3112936083352056 0.0440149099614749 0.9648925189549068 1.0 1.0 46 P49917,Q96EK5,O43933,P21359,Q08AM6,O75909,O14802,Q4G0J3,Q5F1R6,P46778,Q9P2D1,Q9BTW9 12 +Hypoplasia of the pons 0.2692284371766943 0.0439913589865929 0.96491129173072 1.0 1.0 19 Q99986,Q9UID3,P08243,Q96N67 4 +Red eye 0.2685049282759741 0.0434506584192853 0.965342296224948 1.0 1.0 19 P49327,P50851,P18074,P26639 4 +Psychogenic non epileptic seizure 0.2934367313710647 0.0433586706815878 0.965415622715804 1.0 1.0 30 Q7Z6Z7,P42858,P21359,Q9Y296,Q9BPU6,O60333 6 +Abnormality of the hypothalamus pituitary axis 0.289546320807608 0.0433094909868329 0.9654548256092336 1.0 1.0 70 O00170,Q8IY37,P42356,Q5F1R6,Q9P2D1,Q9NVI1,P57081,Q14746,P52701,Q9UBS4,Q96IJ6,O14654,Q92908,Q9BUK6,Q07864,P60866,O14802,P40818,P54277 19 +Abnormality of adrenal morphology 0.2895664179306904 0.0432900140979013 0.965470351357012 1.0 1.0 28 O96017,O60826,Q07864,O43933,P42771,P21359 6 +Abnormal uterus morphology 0.2957570233294694 0.0424980947336053 0.9661016305622192 1.0 1.0 32 O96017,O14965,P52701,Q07864,P60866,P20585,P28340,Q9NVI1 8 +Broad finger 0.3057886956267648 0.042419655953449 0.9661641592664474 1.0 1.0 40 Q9Y4X0,P49917,Q7Z6Z7,Q93008,P26196,P42858,Q9Y296,Q9BPU6 8 +Open mouth 0.2901781276962018 0.0422821908079033 0.9662737422654888 1.0 1.0 29 P04350,P62266,P42345,Q01968,P67870 5 +Soft tissue sarcoma 0.2984972001603104 0.0422336143917599 0.966312466047389 1.0 1.0 34 O96017,O14965,P52701,P42771,P49327,P21359,Q13126 7 +Syndactyly 0.2080598112459968 0.0417547601298478 0.9666941997218452 1.0 1.0 94 Q3SYG4,Q93008,P46109,P54132,P48651,O43776,Q9NVI1,Q9UET6,Q14692,P26196,Q13045,P61586,P27635,P49917,Q96EK5,Q9UBC2,Q08AM6,Q9H4L7,O95248,O43924,O14802,O15111,O60826,P28482,Q6NXR4,Q9Y223,Q6W2J9 27 +Aplasia hypoplasia affecting the fundus 0.2808591583629653 0.041534481281754 0.9668698044739998 1.0 1.0 25 P10589 1 +Abnormal lateral ventricle morphology 0.2927172362448619 0.0414695552504976 0.9669215633575208 1.0 1.0 31 P36507,Q05639,Q8IY37,Q15042,Q00610,Q14204,Q9UID3,P67870,Q14738,Q9NVI1 10 +Distal upper limb muscle weakness 0.2308056379544153 0.0414572847502786 0.966931345387876 1.0 1.0 8 Q13501 1 +High narrow palate 0.3014227668776727 0.0414354004504055 0.9669487915419356 1.0 1.0 37 Q06124,O60826,P28482,P26639,P46109,O43933,P48651,Q08AM6,P53618,Q12873,Q9Y223,Q6W2J9,P18074 13 +Hypsarrhythmia 0.3032678094164208 0.0412600073985056 0.9670886153751466 1.0 1.0 60 Q13618,Q9Y263,O60701,Q08209,P21359,Q6DN90,Q9Y6D5,Q9ULK4,Q13885,P08243,Q96F07,Q08J23,Q96F86,O60524,O94903,Q9NUQ7,Q9UBB6,Q00610,Q96N67,Q05639,Q8NC96,Q96C86,Q2M389 23 +Abnormality of vitamin b12 metabolism 0.2401430394140574 0.0407182375688696 0.9675205221749354 1.0 1.0 11 Q99707 1 +Hypoplasia of the brainstem 0.2856499656765251 0.0404028183670724 0.9677719833536044 1.0 1.0 28 Q96KP1,Q96EK5,O43505,Q9UPN3,Q13885,Q93008,Q14204,Q7Z460,Q96C36,P43034 10 +Hip dysplasia 0.306983086028791 0.040035674450311 0.9680646849836873 1.0 1.0 52 Q7Z6Z7,Q93008,P42858,Q7LBC6,A1X283,Q13535,O14802,Q9BPU6 8 +Immunodeficiency 0.2879959090867691 0.0393415620234248 0.9686180705470708 1.0 1.0 69 P31146,Q13432,P46109,P21266,Q5F1R6,Q9P2D1,Q9NRZ9,O95394,P14174,P17812,Q6PGP7,P35573,P78527,P49917,Q07864,Q13315,Q9UDY8,Q15477,O14617,P53992,O14646,P28482,P60953,P50851,P40818,Q00653,Q13620 27 +Abnormal ovarian physiology 0.2841109001138525 0.0393325364365275 0.968625266353946 1.0 1.0 28 Q06787,Q6NXR4,O00170,P40818,P54132,P49327,P49770,Q13144,Q13315,Q9P2D1 10 +Bruising susceptibility 0.2835970096240739 0.0389830475941026 0.9689039043997528 1.0 1.0 28 Q06124,P28482,O00170,P40818,P35579,P49327,Q13126,Q6W2J9 8 +Easy fatigability 0.2698237653886126 0.0388766746129804 0.968988713469164 1.0 1.0 22 O00170,Q8IUX1,Q8NCE2,Q06210 4 +Long palpebral fissure 0.2791680886931031 0.038829132357751 0.969026618080377 1.0 1.0 26 Q9UET6,Q13555,Q93008,P63241,O75909 5 +Abnormal dermatoglyphics 0.2735626799784828 0.0382329654518407 0.9695019374727358 1.0 1.0 75 Q06124,P27635,O43709,P62266,Q9Y263,O00170,P42345,O43933,Q15042,Q08AM6,Q9H4L7,Q6W2J9,Q13535,Q5SRE5,Q92917,P46821,Q9P2D1,Q9UID3 18 +Abnormality of lower limb epiphysis morphology 0.260765028701402 0.0381578196864716 0.9695618513989216 1.0 1.0 19 P26373,O00443 2 +Neonatal respiratory distress 0.2727076041457499 0.0375928419144765 0.9700123152141672 1.0 1.0 24 O94903,Q14999,P50570,Q5F1R6,Q86Y56,Q8NCE2 6 +Aplasia hypoplasia of the cerebellar vermis 0.2777866675260631 0.0375312721307577 0.970061406150382 1.0 1.0 73 O60826,Q9NZJ4,Q93008,Q9BPU6,Q15042,P42356,Q13535,O14802,Q9UID3,Q9Y4A5,P78527 11 +Distal sensory impairment 0.3033563978196686 0.0370833902170556 0.9704185156058412 1.0 1.0 48 Q9NZJ4,Q14204,O95248,Q5TAQ9,P38935,O14802 6 +Abnormal glial cell morphology 0.2916751791917415 0.036271283073372 0.9710660476544092 1.0 1.0 65 O96017,P52701,Q9BTW9,P42345,P42858,P20585,P42771,P21359,Q7KZN9,Q13144,Q99986,O75165,Q13501,Q7LBC6,P54277,Q9Y3I1 16 +Hypochromic anemia 0.2393258273310676 0.0361318191979894 0.9711772508346048 1.0 1.0 13 P49327,Q8N8R5,Q96Q11,Q9UER7 4 +Aplasia hypoplasia of the nipples 0.2543843558689406 0.0360117552453068 0.971272985704583 1.0 1.0 18 Q08AM6,O60826 2 +Central adrenal insufficiency 0.2145430271483196 0.0359276925948813 0.9713400146197392 1.0 1.0 6 O00170,Q00653 2 +Neoplasm of the thyroid gland 0.2720128365034201 0.0357425222956091 0.9714876643094568 1.0 1.0 25 O96017,P52701,P60866,P20585,P42771,P49327,P54277 7 +Highly arched eyebrow 0.2935146284468289 0.0354797045282093 0.971697229625356 1.0 1.0 63 Q2VPK5,P68400,Q9H3P2,Q9P2D1,Q9Y4A5,P26196,P42858,Q9Y296,Q96F07,Q96EK5,Q7Z6Z7,O43924,Q5SRE5,Q12830,Q13555,P28482,P62266,P60953,Q6W2J9,Q9BPU6 20 +Ambiguous genitalia 0.2634085253832305 0.0349778907146682 0.9720973707371254 1.0 1.0 22 O75845,Q2VPK5,Q8IY37,Q8NCM8,O60566,Q14839,Q15392,Q96EX3,Q15645,Q9H0U9,Q96GM8,O43683,O43684 13 +Generalized hyperpigmentation 0.2372057355499773 0.0349568757796857 0.9721141279814705 1.0 1.0 13 P36507,Q7Z392,O00170,P40818,Q96IJ6 5 +Chronic otitis media 0.2826987170713736 0.034784365595675 0.9722516875348044 1.0 1.0 31 P57076,P53992,O95394,O43709,Q06787,Q03518,Q9UIG0,Q13045,Q01968,P40763,Q9H3P2,Q86Y56 12 +Dilatation of the cerebral artery 0.2295614307136867 0.0344242556902887 0.9725388416879102 1.0 1.0 11 P21359 1 +Tachypnea 0.2541282531717785 0.0342899355649706 0.9726459504072644 1.0 1.0 19 P38935,P53621,O43924,P50747 4 +Tented upper lip vermilion 0.2644622504532139 0.0341630508967713 0.9727471304437754 1.0 1.0 23 P57081,Q05639,Q6PJG6,Q9Y263,P60953,Q13045,Q96F07 7 +Multiple joint contractures 0.2533174156111899 0.0338569292154085 0.972991238987612 1.0 1.0 19 P26639,Q5TBB1,P35251,Q92917,P18074 5 +Abnormal growth hormone level 0.2751182924544992 0.0337597310051952 0.9730687476298758 1.0 1.0 28 P57081,Q07864,O00170,O14802,Q5F1R6,Q9P2D1 6 +Cerebral visual impairment 0.2866816178707895 0.0332108743273656 0.9735064264478448 1.0 1.0 66 Q08209,P10589,Q9BSJ2,Q12873,Q6DN90,Q9ULK4,O60610,P08243,Q14204,Q08J23,Q96F86,P67870,O60524,Q9UBB6,Q00610,Q96N67,Q05639,Q15042,Q9UID3,Q96C86,Q2M389,Q01433 22 +Finger syndactyly 0.286528907451886 0.033202106350719 0.9735134184250523 1.0 1.0 35 Q96EK5,O60826,Q3SYG4,P27635,O15111 5 +Delayed myelination 0.245452779337406 0.0327721086374213 0.9738563203440364 1.0 1.0 83 P00374,Q16512,O14617,O94903,P57678,Q9Y263,Q8IY37,O60701,P26196,Q15042,P08243,P10589,O43776,Q5SRE5,Q9BV10,Q9Y4A5 16 +Widened subarachnoid space 0.2732029285676149 0.0327144165434122 0.973902327305988 1.0 1.0 28 Q9UET6,O94903,Q93008,Q00610,Q14204,O43776,Q9BV10,P67870 8 +Urinary incontinence 0.295771600792038 0.0326560349240829 0.9739488842231004 1.0 1.0 45 Q9NZJ4,Q93008,P53618,P38935,O95248,P26358,Q9BTW9,Q8NCE2 8 +Hand clenching 0.2225130467323407 0.0326165263167237 0.9739803907472384 1.0 1.0 10 Q6W2J9 1 +External ear malformation 0.2528019181623097 0.0321787924032167 0.9743294686301728 1.0 1.0 20 P32929,O43933,P07437,Q8NCH0,P56589,Q15555,Q9P2D1,Q6W2J9,Q9NVI1 9 +Narrow palate 0.296497802896336 0.0321781333668062 0.9743299941929816 1.0 1.0 49 Q06124,O60826,P28482,P26639,O43933,Q01968,Q08AM6,P53618,Q6W2J9,Q9BPU6,P18074 11 +Hypogonadism 0.2271593930834202 0.0320971542313573 0.9743945728369524 1.0 1.0 88 Q3SYG4,O00170,Q8IY37,O43933,P48651,P28340,Q4J6C6,Q9P2D1,A6NHR9,Q9NVI1,O43709,P17612,Q92620,P18074,Q8IWS0,Q06124,Q07864,Q9BZH6,Q9UIG0,O00429,O14802,Q13315,O43395,Q06787,P22681,Q9NW08,Q15042,Q13620,Q6P2Q9 29 +Kinetic tremor 0.2870786130862275 0.0319396000869889 0.9745202184351396 1.0 1.0 37 P26639,Q9NZJ4,P07814,Q9NW08,P35251,O14802,P18074,Q9Y3I1 8 +Pruritus 0.2578612481645108 0.0308117681347439 0.9754196552624989 1.0 1.0 23 Q9P2D1,P49917,Q9Y5L0,P22681 4 +Joint hyperflexibility 0.2912653988677851 0.0303591134250568 0.9757806525732268 1.0 1.0 44 Q06124,P49917,P53992,O43709,Q14999,Q15436,P28482,P22681,Q93008,P46109,Q9UIG0,Q01968,P48651,P40763,Q99741,Q13535,Q08J23,Q8IWS0 18 +Prematurely aged appearance 0.287694662439401 0.0303317196002375 0.9758024996219296 1.0 1.0 40 Q06124,O43709,Q15042,P49327,Q13535,O14802,Q13315,Q13126,P18074 9 +Facial hypertrichosis 0.2891195441234664 0.0303207498860459 0.9758112481636628 1.0 1.0 61 Q9UPP1,P68400,O00170,O60701,Q9BSJ2,Q9NR45,Q13045,Q9Y4X0,Q96EK5,Q96N67,O14802,Q69YN2,Q12830,P62266,P60953,Q15042,Q9Y223,P46821,Q9BTW9 19 +Abnormal choroid morphology 0.2701332303924533 0.0301293003110304 0.9759639330647668 1.0 1.0 29 O60826,O60231,O43933,P21359,Q01968,Q9P2D1,Q6W2J9 7 +Amblyopia 0.2423283537974459 0.0299708461726591 0.9760903041053928 1.0 1.0 18 Q01968,P10589 2 +Capillary malformation 0.2265704097522273 0.0299004535053153 0.9761464441674466 1.0 1.0 13 O43709,P21359 2 +Generalized joint laxity 0.2261027826729471 0.0297080062866153 0.9762999266480004 1.0 1.0 13 Q9BUK6 1 +Antenatal onset 0.2255665199019063 0.0294902135643094 0.9764736239928158 1.0 1.0 13 P27635,O15111 2 +Aplasia hypoplasia of the nails 0.2733961612753765 0.0294466511236642 0.976508366703274 1.0 1.0 71 P49917,O60826,O43709,Q7Z6Z7,O15357,P26639,Q8IY37,P28482,Q99575,P63241,Q08AM6,Q9H4L7,O14802,Q5F1R6,Q9BV10,Q9Y4A5,P18074 17 +Self injurious behavior 0.2893908023783911 0.0293332674882561 0.976598794692452 1.0 1.0 44 Q05639,P00492,P27635,Q06787,P28482,O95352,Q00610,Q13045,Q01968,Q14204,Q4G0J3,P67870,Q6W2J9,Q14353 14 +Abnormal rib cage morphology 0.2478835793703537 0.0287414995595254 0.977070758164897 1.0 1.0 81 O15357,O43933,Q01968,Q13535,Q5F1R6,Q9H3P2,Q9P2D1,Q14999,Q06124,P50570,Q99575,Q08AM6,O14802,Q92917,Q9BV10,O60826,P28482,P22681,Q6W2J9,Q8NCE2 20 +Aplasia hypoplasia of the distal phalanges of the hand 0.2744051614597136 0.028608688356088 0.977176682615817 1.0 1.0 33 O15111,O60826,P28482,P42345,Q93008,P51532,Q08AM6,Q8IWS0 8 +Unilateral renal agenesis 0.2491170768761253 0.0281557693519098 0.9775379141689498 1.0 1.0 22 P42695 1 +Abnormality of the lymph nodes 0.2883873244520342 0.0281379572765558 0.9775521205202936 1.0 1.0 46 P49917,Q9UDY8,P22681,P14174,P50851,P29144,P42771,P49327,Q96BN8,P40763,Q6W2J9,Q01844,Q13315,Q9P2D1,Q9UER7 15 +Nephritis 0.248817316193157 0.0280373213336199 0.9776323847183108 1.0 1.0 22 P53621,P49327,Q9UBS4,Q9P2R3,Q9Y5K6 5 +Hypertriglyceridemia 0.2511588700291029 0.0279264016199082 0.9777208512045974 1.0 1.0 23 O14802,P28340,P31751,P35573 4 +Skeletal muscle hypertrophy 0.2853780925084122 0.0276873447823821 0.977911517236105 1.0 1.0 43 O60231,O43709,O00170,P50570,O00443,O43933,Q99575,P51532,O14802,Q8NCE2,Q01433 11 +Decreased circulating antibody level 0.2878367759170351 0.0275914029841581 0.977988038481403 1.0 1.0 47 P68400,P54132,P49327,P21266,Q9NRZ9,P98170,P14174,P17812,P40763,Q6PGP7,P18074,P26639,P42345,Q13315,Q9BV10,Q15477,P50851,Q00653,Q14790,Q96Q11 20 +Abnormal metatarsal morphology 0.2642210501555137 0.0275224263612511 0.9780430529713506 1.0 1.0 29 P49917,P28482,O43933,Q08AM6,A1X283 5 +Neoplasm of the endocrine system 0.2830731927293212 0.0274889895613716 0.9780697215875704 1.0 1.0 41 O96017,P52701,O00170,P40818,P60866,P20585,P42771,P49327,P21359,Q9UBS4,Q9UER7,P54277,O60333 13 +Cavum septum pellucidum 0.2162539612871 0.0272813820478818 0.97823530631535 1.0 1.0 12 Q9BV10,Q14738,P28482 3 +Short philtrum 0.2704571615398132 0.0271944633540307 0.9783046316780296 1.0 1.0 71 P57081,Q96EK5,O60826,Q7Z6Z7,Q8IY37,Q9BPU6,Q15042,Q96N67,Q08AM6,A1X283,O14802,Q4G0J3,Q9UID3,Q9Y4A5 14 +Preaxial polydactyly 0.225524658759685 0.0270470191903195 0.9784222318422796 1.0 1.0 15 Q8TD19,Q2VPK5,Q9UPP1,Q9H3P2,Q8NCM8,O43924,Q9BXW9 7 +Abnormal pleura morphology 0.2460685905577516 0.0269938978014965 0.9784646011084313 1.0 1.0 22 Q06124,P22681,P14174,P49327,Q92917,Q9UID3 6 +Abnormal meningeal morphology 0.2484689902419448 0.0269023955030427 0.9785375828750338 1.0 1.0 23 O43776,Q9NZJ4,P21359 3 +Aplasia hypoplasia of toe 0.2776473562539913 0.0266542377009631 0.9787355131749692 1.0 1.0 38 P49917,Q7Z6Z7,P26196,P42858,Q08AM6,Q9Y296,Q9P2D1,Q9BPU6,Q8IWS0 9 +Inability to walk 0.2259727079816471 0.0265368112578699 0.9788291727912816 1.0 1.0 87 Q9H269,Q9BUK6,Q96C86,Q9BTW9,P57678,Q9C0E8,P42858,Q96N67,Q08AM6,P53618,Q7Z460,Q9UID3,P27635,P26640 14 +High anterior hairline 0.2490132516860576 0.0261702564377256 0.9791215396780166 1.0 1.0 24 O75909,O43933,P29372 3 +Delayed puberty 0.2845281625328481 0.0260413659431942 0.9792243443762084 1.0 1.0 58 Q06124,P27635,P06737,O00170,Q8IY37,Q93008,Q9NW08,Q15042,P21359,Q01968,O14802,Q13315,Q9P2D1,Q8IWS0 14 +Abnormal iris pigmentation 0.2402834227613415 0.0259315861897616 0.97931190637635 1.0 1.0 21 O14617,P28482,O43709,O00203,O43933 5 +Interictal eeg abnormality 0.2252462670700241 0.0258066220115256 0.97941158000785 1.0 1.0 87 Q9Y263,O60701,Q08209,P21359,P42356,Q9BSJ2,Q6DN90,Q9Y6D5,Q9ULK4,Q13885,P08243,Q08J23,P27635,Q96F07,Q96F86,O60524,O94903,Q9NQZ5,Q9NUQ7,Q9UBB6,Q00610,Q96N67,Q05639,Q8NC96,P46821,Q2M389,Q96C86,Q13618 28 +Thoracic aortic aneurysm 0.2726185239012123 0.0257688489255233 0.9794417085504672 1.0 1.0 36 O43709,Q7Z6Z7,P42858,Q9UBS4,Q9Y296,Q9P2D1,Q9BPU6 7 +Sensorimotor neuropathy 0.2656116706487743 0.025722099107772 0.9794789971482298 1.0 1.0 32 P38935,Q9NZJ4 2 +Hydroureter 0.2075300436208876 0.0256319810712092 0.9795508772386776 1.0 1.0 11 Q6W2J9 1 +Diminished movement 0.2335418159713618 0.0256146461089455 0.9795647039976764 1.0 1.0 19 P42858 1 +Pelvic kidney 0.2001773053096537 0.025592045487047 0.979582730775426 1.0 1.0 9 O43709 1 +Abnormal autonomic nervous system physiology 0.2700306294024638 0.02538415987124 0.9797485456293836 1.0 1.0 35 Q06787,O60333,Q04637,O95163,Q9Y5L0,Q99996,P50336,P35251,O14802,Q96IJ6,O75165,Q9Y3I1 12 +Chronic lung disease 0.1991762387456844 0.0253140503749111 0.9798044669442932 1.0 1.0 9 P50851 1 +Abnormality of bone marrow cell morphology 0.2830273105741306 0.0249849857195656 0.9800669395312616 1.0 1.0 57 P00374,P49917,Q07020,P22681,P50851,O76094,P61254,P49327,Q13535,Q13315,Q5F1R6,Q6W2J9,Q9NVI1 13 +Abnormal thyroid morphology 0.276995261744421 0.0248622669599622 0.9801648245276358 1.0 1.0 41 O96017,P49917,P52701,P50851,P60866,P20585,P42771,P49327,Q9P2D1,P54277,O14654 11 +Aplasia hypoplasia involving bones of the thorax 0.2713726337319505 0.0247102143303352 0.9802861077117746 1.0 1.0 37 Q06124,O60826,Q14999,Q14839,Q08AM6,Q13535,Q9BV10,Q6W2J9 8 +Multifocal epileptiform discharges 0.2559639479783173 0.024497630348782 0.9804556738567558 1.0 1.0 29 O60524,Q9ULK4,O94903,Q96C86,Q08209,Q9UBB6,Q96N67,Q6DN90,Q08J23,Q96F86,Q2M389 11 +Intellectual disability moderate 0.2533101502149147 0.0242082501665092 0.9806864973786824 1.0 1.0 77 P00492,Q93008,Q08209,P51532,P48651,Q4J6C6,Q6DN90,Q9UET6,Q9ULK4,O95394,Q15021,Q14204,Q08J23,P67870,Q96F86,Q9H269,O60524,Q9UBB6,Q00610,O14802,Q69YN2,Q05639,Q15003,Q06787,Q9BTW9,Q6NXR4,Q96C86,Q14738,Q2M389 29 +Abnormal aortic valve cusp morphology 0.2521506007491798 0.0240032903827339 0.9808499841184506 1.0 1.0 28 O43709,P22681,P61254,Q6PGP7,Q6W2J9,Q15477 6 +Patent ductus arteriosus 0.2081536103550774 0.023661811716115 0.9811223673065508 1.0 1.0 91 Q2VPK5,Q93008,O43933,P51532,Q9P2D1,Q9Y4A5,Q9Y6D5,Q9NVI1,O43709,Q6PGP7,P46777,Q06124,Q9Y4X0,P62854,Q9BV10,Q15477,O60826,P46821,Q6W2J9 19 +Abnormal metabolism 0.2794450610022522 0.0235516250682408 0.9812102590382126 1.0 1.0 48 Q14746,Q99707,P27708,Q96C23,P49327,Q01968,Q9Y6B6,Q5F1R6,P18074 9 +Abnormal subarachnoid space morphology 0.2552453732455988 0.02294676956625 0.9816927334850004 1.0 1.0 31 Q9UET6,O94903,Q93008,Q00610,Q14204,O43776,Q9BV10,P67870 8 +Retinal atrophy 0.2527418464876588 0.0228454856449161 0.9817735251824568 1.0 1.0 30 Q9BPU6,P42858,Q7Z6Z7,Q9Y296 4 +Lethargy 0.2408994129422942 0.0228332376460284 0.9817832951231592 1.0 1.0 81 Q8IUX1,Q9NPL8,P08708,Q07020,P62847,P62081,P61353,P62854,P60866,P42766,O43772,P62899,P61313,P50747,P40818,Q13144,O00217 17 +Non motor seizure 0.2782262378358279 0.0227216512664864 0.9818723050798346 1.0 1.0 50 P00374,O94903,Q93008,Q96N67,P42356,Q14204,P67870 7 +Abnormal number of teeth 0.2404189568782756 0.0224805128172033 0.9820646565913604 1.0 1.0 81 Q9Y4X0,O43709,Q7Z6Z7,P62266,Q9NW08,Q8IY37,A5YKK6,O00443,Q99575,Q01968,Q13535,O14802,Q5F1R6,Q96F07,Q9P2D1,Q6W2J9 16 +Sepsis 0.2363852111900636 0.0224380018224017 0.9820985669042056 1.0 1.0 24 P49917,P50851,Q96C23,Q5F1R6,Q9P2D1 5 +Abnormal renal pelvis morphology 0.2753030453996696 0.0223227473162398 0.9821905036676044 1.0 1.0 61 P49917,O60826,Q07864,P57678,Q93008,P26196,O43933,P41252,P21359,Q15042,Q6W2J9,O14802,Q9P2D1,Q9Y4A5 14 +Abnormal ileum morphology 0.2073584061258853 0.0222141471308681 0.9822771325971684 1.0 1.0 15 Q93008,Q9NVI1 2 +Metaphyseal widening 0.238104663142724 0.0221989465982145 0.9822892578774458 1.0 1.0 25 Q5F1R6,Q08AM6,A1X283,O15357 4 +Asthma 0.23614215857723 0.0217388077484862 0.9826563069728048 1.0 1.0 25 P49917,P53992,O95394,P42345,P50851,Q00653,Q9UID3,Q08J23,P18074 9 +Abnormal brainstem morphology 0.2207018838091917 0.0217025556907438 0.9826852251075536 1.0 1.0 87 Q8IUX1,Q96EK5,Q9NPL8,Q9NZJ4,Q93008,Q96N67,Q99986,Q14204,P26358,Q9UID3,Q9BTW9,Q9Y4A5,O00217 13 +Normocytic anemia 0.185165519281642 0.0215778381354044 0.9827847120218608 1.0 1.0 10 Q5F1R6,P04075,O75533 3 +Abnormality of lower lip 0.2640164959383393 0.0211411212213259 0.9831330822252018 1.0 1.0 69 Q06124,Q9NR45,Q96EK5,O43709,Q14999,Q7Z6Z7,O00170,P62266,O60701,Q93008,P22681,Q15042,P51532,Q01968,Q96N67,P27635,P18074 17 +Nasal speech 0.2637116861539313 0.0208470743100635 0.983367646017062 1.0 1.0 40 Q9UPP1,Q7Z6Z7,O95352,P26196,P42858,Q9Y296,Q9BPU6 7 +Abnormal odontoid tissue morphology 0.2712704548389865 0.0208408845559355 0.9833725836535684 1.0 1.0 47 O43709,Q14999,O00443,O43933,Q9HC07,P21359,Q01968,Q13535,Q5F1R6,P18074 10 +Neoplasm of the liver 0.2628493000579778 0.020612383779746 0.983554861737692 1.0 1.0 40 P52701,P06737,P60866,Q9Y5L0,P42771,P49327,Q6PGP7,Q15477,P54277 9 +Scapular winging 0.2270697253725466 0.0204618966089564 0.9836749078089176 1.0 1.0 24 Q06124,Q14999,Q9Y5L0,Q9Y223,Q13501,Q06210 6 +Nail dysplasia 0.2516681762079115 0.0204122835369777 0.9837144850469915 1.0 1.0 34 Q9Y4A5,Q13535,P18074,Q99575 4 +Downturned corners of mouth 0.2589728238812815 0.0204054345272275 0.98371994862816 1.0 1.0 38 P57081,Q05639,Q8IY37,P40763,O14802,Q9H3P2,P67870 7 +Congenital hip dislocation 0.2343433829891817 0.0202419472395169 0.9838503656734476 1.0 1.0 27 Q93008,Q14999,P57678,Q9BTW9 4 +Atrophy degeneration involving the corticospinal tracts 0.1865713902880073 0.0201463340331277 0.98392663842088 1.0 1.0 13 Q14203,Q13501,O43709 3 +Proximal muscle weakness in lower limbs 0.2052199036651709 0.0200875138152251 0.9839735606691432 1.0 1.0 18 P50570,Q14204,Q8NCE2 3 +Abnormality iris morphology 0.2368816737812469 0.020076741875119 0.983982153700919 1.0 1.0 81 Q96IJ6,Q96EK5,O14617,O60826,P52701,O60333,P28482,O43709,O43505,O00203,P26196,O43933,P21359,Q01968,Q9H3P2,Q9P2D1,Q6W2J9,Q9NVI1 18 +Micropenis 0.2643106816896667 0.0199787993181368 0.9840602848837164 1.0 1.0 67 Q06124,P49917,O43505,Q07864,Q7Z6Z7,Q8IY37,P26196,Q14839,Q9BPU6,Q08AM6,Q9BV10,Q9P2D1,P18074,P78527,Q8IWS0 15 +Abnormality of dental morphology 0.2615584779234788 0.0199422090729117 0.9840894738601154 1.0 1.0 69 P57081,O43709,Q7Z6Z7,P28482,Q9UID3,Q8IY37,O00443,O43933,P42858,Q01968,Q6W2J9,Q5F1R6,Q9BPU6,Q9Y296 14 +Abnormality of corneal size 0.2585611782233547 0.0199058975631822 0.984118440503122 1.0 1.0 39 O43505,Q96EK5,O43709,P26639,Q15042,A1X283,Q6W2J9,P18074 8 +Spina bifida occulta 0.2104651273150481 0.019837882595833 0.9841726978815026 1.0 1.0 20 Q06124,P49917,Q14999,O43709,Q9UIG0,P09884,Q08J23 7 +Hyperlordosis 0.2697310285950614 0.0197766036267977 0.9842215818346052 1.0 1.0 50 Q14999,O43709,P28482,O00443,Q15042,Q99575,P21359,Q6W2J9,Q8NCE2,Q06210 10 +Elbow flexion contracture 0.2340681831253173 0.0196993569775897 0.9842832037386244 1.0 1.0 28 Q13535 1 +Dysmetria 0.270746581763384 0.0196791269540086 0.9842993418337036 1.0 1.0 56 Q9BUK6,Q9NPL8,O43709,Q9NZJ4,Q9NW08,Q9C0E8,P21359,P42356,P35251,O14802,Q13501 11 +Dermal atrophy 0.2237734036767735 0.0194151596517439 0.9845099170348584 1.0 1.0 25 O00170,P53618,P28340,Q15334,P18074 5 +Anorectal anomaly 0.2554304669686949 0.019288670480134 0.9846108218958938 1.0 1.0 72 O96017,P49917,P52701,O60826,O43709,Q07864,P29372,Q93008,P26196,Q14839,P20585,P42771,P28340,Q9P2D1,Q6W2J9,P54277 16 +Cleft upper lip 0.2435440257011934 0.019172857686659 0.9847032100505204 1.0 1.0 33 Q9UPP1,P29372,P46777,Q9H3P2,Q9P2D1,Q6W2J9,O15111 7 +Sleep apnea 0.2155724267666673 0.0191506700405164 0.9847209099810494 1.0 1.0 23 O00170,Q9Y223,Q4G0J3,Q9UID3 4 +Abnormality of limb epiphysis morphology 0.2409213433001773 0.0191186996876195 0.9847464139626358 1.0 1.0 32 P26373,Q13535,O00443 3 +Retinopathy 0.2303233296662736 0.0190770119858744 0.984779669870996 1.0 1.0 28 O95352,P42771,P49327,Q9Y6B6,Q9H3P2,P18074 6 +Schizophrenia 0.2100806024230474 0.0188905400654508 0.9849284261300252 1.0 1.0 22 Q96QK1,Q9BUK6,Q9UET6,Q04637,O95352,O75165 6 +Genu varum 0.1604716526381893 0.0188068376316097 0.9849951991472884 1.0 1.0 11 Q8WVQ1,P26373,Q9NUQ7,Q7Z2Z2,Q9H1A4 5 +Sandal gap 0.2362212037020492 0.0187406830045439 0.9850479736017348 1.0 1.0 31 P49917,Q12830,P28482,Q9BV10,P46109,Q13535,P61586,Q08J23,Q96C86,Q6W2J9 10 +Embryonal neoplasm 0.2183402635597742 0.0186626948737212 0.9851101882463924 1.0 1.0 25 O96017,Q8IY37,P20585,Q6PGP7,Q15477 5 +Abnormality of the diencephalon 0.2356813155991353 0.0186549756189197 0.9851163462485651 1.0 1.0 31 Q9H269,Q96KP1,O43709,Q9BZH6,O00443,O43924,Q92917,Q9P2D1 8 +Early onset of sexual maturation 0.2587644520036073 0.0185993807409863 0.985160696848452 1.0 1.0 43 O43709,Q7Z6Z7,O00170,P26196,P42858,P21359,Q9Y296,Q9BPU6 8 +Abnormal atrioventricular valve morphology 0.2519846379754671 0.0184762020805101 0.985258962313904 1.0 1.0 39 Q92908,Q06124,O60826,O43709,P28482,Q9NZJ4,P21359,P46777,A1X283,Q9UBS4,Q6W2J9 11 +Abnormal glomerular mesangium morphology 0.1941772837965144 0.0184468524225424 0.9852823759625072 1.0 1.0 19 Q9P2R3,P53621 2 +Esodeviation 0.2560717512133812 0.0183226631108784 0.9853814479522895 1.0 1.0 42 Q16512,Q9Y4X0,Q9H1B7,Q12830,Q7Z6Z7,Q15436,P26639,Q9UBB6,P10589,O43924,P18074 11 +Abnormal circulating albumin concentration 0.2391454889889568 0.018041291186292 0.9856059131606174 1.0 1.0 34 P57081,Q9Y5L0,Q6PGP7,Q9Y6B6,Q9P2R3,Q9Y5K6 6 +Radioulnar synostosis 0.2052531251206474 0.0180119442295195 0.9856293248401056 1.0 1.0 23 Q06124,Q6W2J9,O43709,P22681 4 +Premature ovarian insufficiency 0.1990287062495534 0.0178258429682967 0.9857777883262246 1.0 1.0 22 Q06787,Q6NXR4,P40818,P49327,P49770,Q13144 6 +Immunologic hypersensitivity 0.2418355230916083 0.0177485947056309 0.98583941377288 1.0 1.0 36 P49917,P53992,O95394,O14646,P22681,P42345,P50851,Q00653,Q9Y5L0,P49327,P40763,Q9UID3,Q08J23,P18074 14 +Deviation of toes 0.2537469934060621 0.0175735363437068 0.9859790683551656 1.0 1.0 43 O43709,Q7Z6Z7,Q93008,P42858,Q9Y296,Q9BPU6 6 +Gastrointestinal atresia 0.1738241827926269 0.0175337619178226 0.986010798866544 1.0 1.0 18 P18583,Q8NCM8,O60566,Q15645,Q9BXW9,Q9P2D1,Q7LBC6,O43683,O43684 9 +Arnold chiari malformation 0.1947243062449498 0.0175215219408027 0.9860205634551876 1.0 1.0 22 O14802,Q14839,O43709 3 +Iris coloboma 0.2301214458085921 0.0171781134806404 0.9862945225260952 1.0 1.0 33 Q96EK5,O60826,O43505,Q96IJ6,Q9P2D1,Q6W2J9 6 +Mandibular prognathia 0.241466237066686 0.0170501324877927 0.9863966216311332 1.0 1.0 38 Q9BUK6,P27635,Q14999,O00170,Q01968,A1X283,P67870,Q06210 8 +Wide nose 0.243103413367344 0.0169818003871028 0.9864511348667327 1.0 1.0 39 Q9NR45,O00170,P51532,P40763,Q6PGP7,Q4G0J3,Q9BV10,Q15477,Q9HCK8 9 +Abnormal distal phalanx morphology of finger 0.2593924915497181 0.0169559162577054 0.9864717844407928 1.0 1.0 51 Q9Y4X0,O15111,O60826,P28482,P42345,Q93008,P41252,Q15042,P51532,Q08AM6,Q8IWS0 11 +Limb girdle muscle weakness 0.2008833029435213 0.0167822827205055 0.9866103042487364 1.0 1.0 26 Q13126 1 +Hypopituitarism 0.2346271604799835 0.0167726802097557 0.9866179648655626 1.0 1.0 36 P57081,Q96IJ6,Q7Z392,Q07864,Q9BZH6,O00170,Q00653,Q4J6C6,O14802,Q5F1R6,Q9P2D1,Q9NVI1 12 +Aortic aneurysm 0.2599846027464254 0.0165419550634467 0.9868020313592938 1.0 1.0 58 Q12830,O95394,O43709,Q7Z6Z7,Q06787,P28482,Q5TBB1,P46109,P26196,P42858,Q9UIG0,Q9UBS4,Q9Y296,Q9P2D1,Q9Y3Z3,Q9BPU6,Q9Y6D5,P46821 18 +Renal hypoplasia 0.2235947870454795 0.0165060911402137 0.9868306427235918 1.0 1.0 33 Q15058,O43709,P57678,Q9UIG0,P33992,Q6PGP7,O43924,Q6W2J9,Q9P2D1,Q9Y4A5,Q15477,Q9NVI1 12 +Limb hypertonia 0.2405675727780125 0.0163556051313819 0.9869506969797583 1.0 1.0 40 Q05639,Q9Y263,P40818,Q00610,P42356,O14802,Q96F07,P42695 8 +Abnormal pulmonary interstitial morphology 0.2132973246338839 0.0162425145309535 0.9870409182389076 1.0 1.0 31 P57076,O14617,P53621,Q13432,Q9Y285,P14174,O00203,P49327,P40763,Q9NSD9,Q86Y56,Q86TI2 12 +Delayed ability to walk 0.246386826627758 0.0161774701101204 0.9870928093600442 1.0 1.0 73 P27635,Q7Z6Z7,O95352,Q9BPU6,Q15042,Q9Y5L0,Q7LBC6,P53618,O43776,Q14204,P67870,Q9Y4A5,Q01433 13 +Impairment of activities of daily living 0.2584017084374519 0.0161562070028936 0.9871097726480508 1.0 1.0 58 Q9BTW9,Q9NZJ4,Q93008,P53618,P38935,O95248,P26358,Q13501,Q9BPU6,Q8NCE2 10 +Urinary tract neoplasm 0.2355052921460283 0.0160287389995518 0.9872114642315752 1.0 1.0 39 O96017,O14965,P52701,Q8IY37,P42771,P21359,P54277,O60333 8 +Narrow mouth 0.2471867915502622 0.0159010075924514 0.9873133661620952 1.0 1.0 72 Q9Y4X0,P27635,P28482,Q7Z6Z7,Q96C86,P26196,P42858,Q15042,P28340,O14802,Q9Y296,Q9P2D1,Q9BPU6 13 +Delayed cns myelination 0.2193138797644725 0.0158891242970627 0.9873228464623278 1.0 1.0 34 O14617,O94903,Q8IY37,O60701,P26196,Q15042,O43776,Q5SRE5 8 +Abnormality of hair texture 0.256221601186809 0.015823504605848 0.9873751968193754 1.0 1.0 55 Q06124,P49917,O75182,P26639,P42345,P62266,Q93008,Q01968,Q6PGP7,P46778,Q9BPU6,P18074,Q15477 13 +Dysphonia 0.2215613396642153 0.0158012087402626 0.9873929841224712 1.0 1.0 35 P04350,O75569,O43709,P21359,P42356,P18074,O60333 7 +Stage 5 chronic kidney disease 0.1726327999593845 0.0156702788105458 0.9874974381589424 1.0 1.0 27 Q9P2R3,Q8IUX1,Q9UBS4 3 +Redundant skin 0.1905726179563003 0.0156573730856677 0.9875077341743992 1.0 1.0 29 P36507,O43709,O43933,Q9UIG0,P48651,Q08AM6,A1X283,Q9BV10 8 +Epileptic spasm 0.2543518478636576 0.0154246474246454 0.9876933999631796 1.0 1.0 63 Q13618,Q8IY37,O60701,Q08209,P42356,Q6DN90,Q9ULK4,Q14204,Q08J23,Q96F86,P67870,O60524,O94903,Q9NUQ7,Q9UBB6,Q00610,Q96N67,P43034,Q05639,O60231,P28482,Q96C86,Q9BTW9,Q2M389 24 +Aphasia 0.2257181621409805 0.0153796915103828 0.9877292653387166 1.0 1.0 38 Q7Z6Z7,P42858,Q01968,Q9Y296,Q13501,Q9BPU6 6 +Childhood onset 0.2206498505406845 0.0152548508473279 0.9878288620919432 1.0 1.0 37 Q9H269,O60524,P53621,P29144,Q9NUQ7,O60610,Q00653,Q01968,Q14204,P40763,Q8TEQ6 11 +Broad nasal tip 0.2514567249252415 0.0151695313395447 0.9878969293337164 1.0 1.0 53 Q9UPP1,Q7Z6Z7,Q93008,Q15042,Q96N67,O75909,A1X283,P35573,Q7LBC6 9 +Tetralogy of fallot 0.2317363890501007 0.0151682993592559 0.9878979121986852 1.0 1.0 41 O15111,O60826,O43709,Q14839,P51532,Q08AM6,Q6PGP7,P46777,Q9P2D1,Q15477,Q9NVI1 11 +Type ii diabetes mellitus 0.2277336932012117 0.0150686635403872 0.9879774009953946 1.0 1.0 40 P49917,P17096,P49589,O43709,O00170,Q9UIG0,P31751,P54132,O43395,Q15555,O14802,Q13315,Q92620,Q6P2Q9,P20839 15 +Intestinal malrotation 0.1772550097530517 0.0148605530375921 0.9881434305608864 1.0 1.0 32 Q92908,O60826,P57076,Q9BV10,Q8NCH0,Q9NSD9,Q86Y56,Q6W2J9 8 +Eeg with focal epileptiform discharges 0.2214729236098516 0.0148587217229899 0.9881448915772216 1.0 1.0 39 O60524,Q9ULK4,O94903,Q96C86,Q08209,Q9UBB6,Q96N67,P42356,Q6DN90,Q08J23,Q96F86,Q2M389 12 +Hemolytic anemia 0.185276246848434 0.0146191642116313 0.9883360100564258 1.0 1.0 34 Q969U7,O95394,P50851,P29144,P49327,P40763,Q8NB49,P08237,P06744 9 +Kyphoscoliosis 0.2510770427257005 0.014594758503662 0.988355480916715 1.0 1.0 59 Q06124,P04350,O95352,Q9HC07,Q15042,Q99575,P21359,A1X283,O14802,Q6W2J9,P18074 11 +Motor delay 0.1586735775772219 0.0145741170697009 0.9883719486467007 1.0 1.0 239 O75569,O60701,A5YKK6,O95352,Q13614,O43776,Q12873,A1X283,P53618,Q9Y4A5,P57081,Q9NRZ9,Q9UET6,Q9ULK4,P06737,P26196,P42858,Q9Y5L0,P40763,Q14204,Q9Y296,P27635,P67870,Q96F86,Q06210,P04350,Q969U7,Q9BUK6,O60524,Q7Z6Z7,O00203,P50570,Q9BV10,Q16512,P62266,Q15042,Q7LBC6,Q6W2J9,Q9UID3,Q2M389,Q96C86,Q9BPU6,Q8NCE2,Q01433 44 +Arthrogryposis multiplex congenita 0.1924960171578436 0.0145655980785605 0.9883787450967894 1.0 1.0 35 P22314,Q8TD19,Q15058,Q08209,P42356,Q15392,Q00535,P40763,Q8NCH0,Q9BTW9,P18074,Q06210 12 +Hypermetropia 0.2437066390230223 0.0145351124231062 0.9884030665558824 1.0 1.0 50 O43709,Q7Z6Z7,P07814,Q93008,P10589,O14802,Q5F1R6,P27635 8 +Prenatal movement abnormality 0.2505526848979534 0.0144737832999846 0.9884519949693148 1.0 1.0 60 Q05639,O94903,P50570,Q8NC96,Q08209,O00429,Q13045,Q00610,Q7KZN9,P38935,Q5SRE5,Q92917,Q9H3P2,Q96F07,Q9BPU6,Q8NCE2,Q06210,O15111 18 +Gliosis 0.2345957698692546 0.0143483331024224 0.988552079351802 1.0 1.0 46 Q9BTW9,P42858,Q99986,Q7KZN9,O75165,Q13501,Q7LBC6,Q9Y3I1 8 +Abnormality of the ulna 0.2039135603318515 0.0141075820461654 0.9887441514601016 1.0 1.0 39 Q06124,Q14999,O43709,P22681,P61254,Q9P2D1,Q6W2J9,Q9NVI1 8 +Full cheeks 0.181327454757975 0.0140681026267844 0.9887756483535864 1.0 1.0 37 P36507,O00170,P41252,Q01968,Q00535,A1X283,P35573,Q9P2J5 8 +Abnormality of globe size 0.2457843495692106 0.0139399921577912 0.9888778556962 1.0 1.0 67 O75569,Q9BUK6,O43505,P26639,Q15042,Q96N67,Q01968,Q08AM6,A1X283,Q13535,Q9P2D1,Q6W2J9,P18074,O15111 14 +Delayed eruption of teeth 0.2456091983571357 0.013934069637788 0.9888825807245528 1.0 1.0 56 Q9Y4X0,P49917,Q9UET6,Q14999,Q9NW08,Q93008,P51532,Q01968,A1X283,O14802,Q5F1R6,Q9P2D1,Q6W2J9 13 +Cns hypomyelination 0.2076480815469285 0.0138508790675452 0.9889489507910862 1.0 1.0 41 P04350,P47897,Q96KP1,Q8N8R5,Q9H7D7,Q9NW08,P49770,Q13144,P54136,O14802,Q9BTW9,P78527 12 +Cerebellar cyst 0.2120706651713955 0.0138133568190457 0.9889788863499642 1.0 1.0 42 O43505,O60826,Q93008,Q6W2J9,O14802,Q9UID3,Q9P2D1,Q9BPU6 8 +Autism 0.2270608554539268 0.0137882293564885 0.9889989332552136 1.0 1.0 46 Q05639,Q9UET6,P27635,O43709,Q06787,Q00610,Q96F07,Q9P2D1,Q9HCK8,Q14353 10 +Aplasia hypoplasia of the skin 0.2452713359429058 0.0137880789878137 0.9889990532206536 1.0 1.0 57 Q9H4L7,P53618,P28340,O14802,Q13126,Q13315,Q15334,Q9Y6D5,P18074,O15111,P46821 11 +Brain imaging abnormality 0.180949657389814 0.0137392537805341 0.9890380064099242 1.0 1.0 39 O75182,P41252,P21359,O14802,Q13501,Q14353 6 +Abnormal blood ion concentration 0.231935874169959 0.0136382430801785 0.9891185937375252 1.0 1.0 77 P61457,P16930,O15357,O00170,P21359,Q01968,Q4J6C6,Q9P2D1,Q14746,O43709,O95163,P41252,P08397,P50336,Q6PGP7,Q10567,O00443,Q9UIG0,Q9BV10,Q15477,O60333,P53992,P40818,Q00653,Q99996,Q9NSD9,Q9UNF1,Q13618 28 +Congenital contracture 0.197756919012613 0.0136164706408019 0.989135964017807 1.0 1.0 41 P50570,P42356,Q99986,Q00535,Q9BTW9,P18074,Q06210 7 +Dialeptic seizure 0.2450682504723819 0.0136007281502418 0.9891485235449452 1.0 1.0 59 P00374,O94903,P42345,Q93008,Q96N67,Q14204,P67870,Q14353 8 +Progressive microcephaly 0.209008046451496 0.0135333200413811 0.9892023024846528 1.0 1.0 43 P47897,Q9Y263,P60953,P08243,Q9BV10,P26640,Q9Y6D5,Q01433 8 +Triangular face 0.1564855847083581 0.0134875142339987 0.9892388468957524 1.0 1.0 40 Q06124,Q12830,Q14999,Q7Z6Z7,O75179,P22681,O94979,Q99741,Q15645,O14802,Q4G0J3,Q14738,O43684,O43683,Q96C36,Q9NVI1 16 +Polyhydramnios 0.2394522942481287 0.0133076280468999 0.9893823624262148 1.0 1.0 55 Q9Y4X0,P27635,P22681,P50570,Q08AM6,Q6PGP7,Q9BV10,Q9P2D1,Q9BTW9,Q7LBC6,Q8NCE2 11 +Intellectual disability profound 0.2176851611207101 0.013306132790874 0.9893835553622892 1.0 1.0 46 Q05639,Q9UET6,Q9BTW9,P31939,Q5TBB1,Q93008,Q00610,Q14204,Q9Y296,P67870,P26640 11 +Thick lower lip vermilion 0.2200019687127044 0.0132297815501373 0.9894444694766 1.0 1.0 47 Q06124,Q9NR45,O43709,Q14999,Q7Z6Z7,O00170,P62266,O60701,Q93008,P22681,P51532 11 +Dilated fourth ventricle 0.2082891925333045 0.0131655655285606 0.989495701986766 1.0 1.0 45 O43505,O60826,Q93008,Q6W2J9,O14802,Q9UID3,Q9P2D1,Q9BPU6 8 +Abnormal neural tube morphology 0.1628710093744406 0.0130348649563024 0.9895999770073888 1.0 1.0 43 Q06124,P49917,Q8TD19,P53992,O43709,Q14999,Q14692,Q99707,Q9UIG0,P21359,P11586,P09884,Q9BXW9,Q08J23,Q9NVI1 15 +Abnormal ureter physiology 0.2248412111480122 0.0129540160102644 0.9896644796871266 1.0 1.0 50 O43709,Q14839,O14802,Q00534,Q9P2D1,Q9Y4A5,P42695 7 +Coloboma 0.1958522145377438 0.0129217220483787 0.9896902443842746 1.0 1.0 45 Q96EK5,O60826,O43505,Q15042,Q96IJ6,Q9P2D1,Q6W2J9 7 +Prominent nasal bridge 0.2256413100693804 0.0128331700319217 0.989760892813002 1.0 1.0 51 Q96EK5,Q3SYG4,P28482,P10589,Q96N67,Q6W2J9,Q9BV10,Q9Y4A5 8 +Osteoporosis 0.2389751047920265 0.0128162334368921 0.9897744051494356 1.0 1.0 69 P27635,Q9UDY8,O43709,P06737,P22681,O00170,Q8IY37,P40818,Q9HC07,Q15042,Q9Y5L0,P21359,A1X283,P28340,Q9P2D1 15 +Malabsorption 0.2360797262081556 0.0127232675321318 0.9898485751619286 1.0 1.0 57 P49917,P52701,O43709,P22681,P42345,P14174,P60866,O43933,P49327,Q01968,Q9Y6B6,Q5F1R6,P18074,P54277 14 +Severe global developmental delay 0.237062931024033 0.0125935480624479 0.9899520680320152 1.0 1.0 70 O14617,Q7Z6Z7,P57678,P26196,Q9BPU6,P42858,O43933,Q9Y296,Q9BV10,Q9UID3,P18074,Q14353 12 +Otitis media 0.2377547525573968 0.0123748829205215 0.9901265239768956 1.0 1.0 64 P54132,Q01968,Q9H3P2,Q86Y56,O95394,O43709,Q03518,Q13045,P40763,O00203,Q9H7D7,Q9UIG0,O14802,Q12830,P57076,P53992,Q06787,P28482,P50851,P29144,Q00653,Q6W2J9 22 +Abnormality of the periorbital region 0.2288245290000999 0.0123286468140433 0.9901634122383468 1.0 1.0 76 P36507,Q9UPP1,O00170,Q93008,O43933,Q9P2R3,Q9Y5K6,P57081,Q9UET6,O43709,Q6PGP7,Q8IWS0,Q92908,P49917,Q96N67,Q9HCK8,O14646,P62266,Q9Y223 19 +Heterotropia 0.2228664809456036 0.012068738958499 0.9903707732738576 1.0 1.0 55 Q9Y4X0,Q9H1B7,Q7Z6Z7,P26639,P60953,Q9UBB6,P10589,Q6XZF7,P27635,Q6W2J9,P18074 11 +X linked recessive inheritance 0.2127208009228496 0.01197963756648 0.9904418607597328 1.0 1.0 53 Q9Y4X0,O60826,Q9UPP1,Q93008,Q01968,P27635,Q8IWS0,O14654 8 +Specific learning disability 0.2336024958105481 0.0118368619070184 0.9905557711770788 1.0 1.0 68 P04350,Q96EK5,O43505,P62266,O00443,P42858,P21359,P42356,Q5F1R6,Q13501,P46821 11 +Enlarged posterior fossa 0.2207343936656842 0.0118214395380311 0.9905680755862838 1.0 1.0 56 Q9NPL8,O43505,O60826,Q93008,A1X283,Q6W2J9,O14802,Q9UID3,Q9P2D1,Q9BPU6 10 +Vascular dilatation 0.2291363772097298 0.0116185707898686 0.99072993031159 1.0 1.0 73 Q5TBB1,P21359,Q9P2D1,Q9Y3Z3,Q9Y6D5,O95394,O43709,P26196,P42858,P40763,Q9UBS4,Q9Y296,P27635,Q06124,Q7Z6Z7,Q12830,Q06787,P28482,Q9NSD9,P46821,Q9BPU6 21 +Generalized onset motor seizure 0.2014976382462098 0.0115762599631457 0.9907636871967568 1.0 1.0 54 Q14746,P67870,Q9C0E8,Q96N67,Q14204,O43776,P27635,Q9BTW9,Q14353 9 +Abnormality of the forearm 0.1797402150920921 0.011538145410679 0.9907940961787948 1.0 1.0 53 Q06124,Q14999,O43709,P22681,P61254,Q13535,Q9BV10,Q9P2D1,Q6W2J9 9 +Abnormal leukocyte physiology 0.2309950960343319 0.0114889201167511 0.9908333696776548 1.0 1.0 68 P68400,P54132,P49327,P11172,P21266,Q9NRZ9,O95394,P14174,P17812,Q9Y5L0,Q96BN8,P40763,Q6PGP7,P18074,P49917,P26639,P42345,O00203,Q9NRW7,Q13315,Q9BV10,Q15477,P53992,P50851,P29144,Q00653,Q14790,Q96Q11 28 +Abnormality of the hallux 0.2173538955545293 0.011392831663862 0.9909100321531774 1.0 1.0 58 O60826,O43709,Q7Z6Z7,Q93008,P42858,Q08AM6,Q6W2J9,Q9Y296,Q9BPU6 9 +Rigidity 0.2119032495228094 0.0113501929240555 0.9909440507457934 1.0 1.0 57 P04350,Q05639,Q06787,Q96F07,Q9Y263,Q04637,Q5TBB1,Q8NC96,Q9C0E8,P42858,Q00610,O75165,Q9Y3Z3,Q9Y3I1 14 +Abnormality of humoral immunity 0.2210400944382516 0.0110458285226393 0.9911868831760866 1.0 1.0 62 P68400,P54132,P49327,P21266,Q9NRZ9,O95394,P14174,P17812,Q9Y5L0,Q96BN8,P40763,Q6PGP7,P18074,P49917,P26639,P42345,Q9NRW7,Q13315,Q9BV10,Q15477,P50851,P29144,Q00653,Q14790,Q96Q11 25 +Abnormal elasticity of skin 0.2238014306236403 0.0109172588710817 0.9912894607306608 1.0 1.0 65 Q06124,O43709,O00170,O43933,P41252,Q08AM6,Q9H4L7,P53618,A1X283,P28340,Q13126,Q9BV10,Q15334 13 +Peripheral axonal neuropathy 0.2057768573699188 0.010902348373086 0.9913013568788218 1.0 1.0 59 O60231,O60524,Q14204,Q5TAQ9,Q96IJ6,Q9BTW9,Q8NCE2,Q01433 8 +Abnormal diaphysis morphology 0.2236960807896885 0.0107745562646656 0.9914033142403076 1.0 1.0 73 P26373,O43709,P28482,O00170,Q9HC07,P21359,Q01968,Q08AM6,A1X283,O14802,Q13126,Q6W2J9 12 +Abnormality of the zygomatic bone 0.2164707239966733 0.0106792771531124 0.9914793315986934 1.0 1.0 79 Q9Y4X0,Q07864,Q14999,P28482,P62854,A5YKK6,Q9HC07,Q15042,O43933,P21359,O14802,Q4G0J3,P35573,Q9P2D1 14 +Abnormality of the cheek 0.1864646870970398 0.0105037566824905 0.9916193688172036 1.0 1.0 60 Q92908,P36507,P04350,O60826,O00170,P41252,Q01968,Q00535,A1X283,P35573,Q9P2J5,Q9P2D1,Q6W2J9 13 +Abnormality of malar bones 0.2216235913784114 0.0104934090205499 0.9916276246019168 1.0 1.0 69 Q9Y4X0,Q14999,Q07864,P28482,P62854,Q9HC07,O43933,Q15042,P21359,O14802,P35573,Q9P2D1 12 +Apraxia 0.2177088692513346 0.0104340115162836 0.9916750143591088 1.0 1.0 66 O14646,Q7Z6Z7,P28482,P26196,P42858,P42356,Q7Z460,Q12873,Q69YN2,Q9Y296,Q13501,Q9BPU6 12 +Aplasia hypoplasia involving bones of the feet 0.220758882296597 0.0103662044880788 0.9917291136141896 1.0 1.0 71 P49917,Q13555,Q7Z6Z7,O15357,Q93008,P26196,Q9BPU6,P42858,Q08AM6,Q9Y296,Q9P2D1,Q9Y4A5,Q8IWS0 13 +Abnormal tracheobronchial morphology 0.2052421391515839 0.0103214336765432 0.9917648336425092 1.0 1.0 63 Q93008,P54132,Q92990,Q86Y56,Q9P2D1,Q9Y4A5,Q9NVI1,O95394,O43709,Q03518,Q13045,P46777,Q9H7D7,Q9UIG0,Q13315,P57076,P50851,Q00653,P29144,Q14790,Q86TI2 21 +Finger clinodactyly 0.1801349442992812 0.0102383140697869 0.9918311499893118 1.0 1.0 93 P46109,O95352,P54132,A1X283,Q13535,Q9P2D1,Q9Y4A5,Q9NVI1,P57081,Q14999,O43709,Q13045,Q08J23,P27635,Q99741,Q92908,Q9Y4X0,Q06124,P49917,Q9UIG0,O43924,Q9BV10,Q12830,P28482,Q6PJG6,P22681,P46821,Q6W2J9 28 +Hip dislocation 0.2093608886411692 0.0101756808664032 0.991881121452126 1.0 1.0 65 Q14999,Q93008,Q01968,Q08AM6,Q13535,Q9BTW9,Q9BPU6 7 +Cerebellar malformation 0.1761172418249143 0.0101513043741441 0.9919005700744314 1.0 1.0 62 O43505,O60826,O43709,Q93008,Q14839,P51532,Q6W2J9,O14802,Q9UID3,Q9P2D1,Q9BPU6 11 +Peripheral axonal degeneration 0.2155386165354247 0.0101015894173245 0.9919402348371524 1.0 1.0 77 O60231,O60524,P35251,Q14204,Q5TAQ9,P38935,Q96IJ6,Q9BTW9,Q8NCE2,Q01433,O60333 11 +Abnormality of mouth shape 0.2120156294147372 0.0100453319303806 0.991985119540022 1.0 1.0 67 P04350,P57081,Q05639,P62266,P42345,Q8IY37,Q00610,Q01968,P40763,O14802,Q9H3P2,P67870,P18074 13 +Toe syndactyly 0.1568687792317553 0.0099662358638758 0.9920482259112412 1.0 1.0 63 P49917,Q9UET6,P28482,Q14692,Q6NXR4,Q93008,P46109,P26196,Q13045,Q9H4L7,O43924,P61586,O14802,Q9Y223,P27635,Q6W2J9,Q9NVI1 17 +Wide mouth 0.1950104657087354 0.0095662489122248 0.992367354102854 1.0 1.0 67 P57081,P49917,O43709,Q7Z6Z7,P42345,P28482,P31939,Q9BPU6,Q7LBC6,Q6PGP7,A1X283,Q4G0J3,Q9Y4A5 13 +Gonosomal inheritance 0.1934421963394478 0.0092657613214244 0.9926070978831488 1.0 1.0 69 Q9Y4X0,O60826,Q9UPP1,Q7Z6Z7,P29372,Q93008,Q01968,P27635,Q8IWS0,O14654 10 +Abnormality of the synovia 0.1933299331250247 0.0087732495904414 0.9930000494014246 1.0 1.0 86 Q06124,Q14999,P57678,O15357,O00203,Q93008,Q14839,Q08AM6,Q01968,Q13535,O14802,Q5F1R6,Q9BTW9,Q9BPU6,Q9NVI1 15 +Lower extremity joint dislocation 0.1960035680424804 0.0083266432970842 0.9933563766404097 1.0 1.0 81 Q5F1R6,Q14999,P57678,Q93008,Q08AM6,Q01968,Q13535,P46821,Q9BTW9,Q9BPU6,Q9Y6D5 11 +Low set posteriorly rotated ears 0.19156828152916 0.0081041605130977 0.9935338862280176 1.0 1.0 79 Q06124,P49917,Q3SYG4,P28482,O43709,Q9Y263,P22681,Q93008,O43933,Q15042,P21359,Q01968,Q9P2D1,Q6W2J9 14 +Abnormality of facial musculature 0.1890035706006354 0.0078740701013024 0.993717465956103 1.0 1.0 81 Q9Y263,Q93008,O43933,Q13614,P42356,P48651,O75165,Q9P2D1,Q9H1B7,Q14203,Q9UET6,Q9BUF5,Q14692,Q06210,Q9Y3I1,Q9BUK6,P50570,O00429,Q13501,Q13555,Q04637,Q9Y223,Q14738,Q8NCE2,Q01433 25 +Variable expressivity 0.1610391303017246 0.0078523492032121 0.9937347961895626 1.0 1.0 77 P00374,Q9Y263,Q5TBB1,Q9Y3Z3,Q15058,Q9BUF5,Q13885,P41252,P54136,O00217,Q06210,P04350,Q9H7D7,O00429,Q00610,P46976,P33993,P43034,P08237 19 +Muscular hypotonia of the trunk 0.1566901130701478 0.0073943423782694 0.9941002221421408 1.0 1.0 80 O75880,P61457,Q9UHD1,Q5TBB1,O60701,O95352,Q9BSJ2,Q9Y3Z3,P26196,P42858,P08243,P54136,Q5THJ4,Q08J23,P04350,P43034,O14617,Q6PJG6,Q8NC96,Q9NSD9,Q96Q11,Q01433 22 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..782165110807807d8bdd4b2a603838a288fa4bd9 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lacrimal punctum morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasal mucus secretion", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of olfactory lobe morphology", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent lacrimal punctum", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary agenesis", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to polysaccharide vaccine", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Dumbbell shaped long bone", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased fibular diameter", "Increased head circumference", "Increased hematocrit", "Increased hemoglobin", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased pulmonary vascular resistance", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal carcinoid", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuchal rigidity", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Paraproteinemia", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior rib cupping", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment depression", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "Systolic heart murmur", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft palate", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCD3", "ABHD12", "ABHD5", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG2", "AMMECR1", "AMPD2", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APRT", "ARCN1", "ARFGEF2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "ATXN10", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS9", "BCAP31", "BCAT2", "BCKDHB", "BCL10", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "C2orf69", "CA8", "CAD", "CALD1", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CCDC22", "CCDC47", "CCNK", "CCT5", "CD2AP", "CD320", "CD3EAP", "CDC40", "CDC42", "CDC6", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CDKN2A", "CELF2", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHM", "CHMP2B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COG2", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "CORO1A", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX6B1", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTU2", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIAPH1", "DIAPH2", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGLN1", "EHHADH", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FAH", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATA6", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GMPPA", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKG", "IMPDH1", "INF2", "INPPL1", "INTS1", "INTS8", "IQSEC1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ITCH", "ITPA", "ITPR2", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIG4", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "MACF1", "MAGED2", "MALT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MCCC1", "MCCC2", "MCEE", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MECR", "MED23", "MESD", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOCS1", "MOCS2", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MYH14", "MYH9", "MYO6", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NARS2", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEK9", "NELFA", "NEMF", "NF1", "NFKB2", "NFS1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOVA2", "NPC1", "NPC2", "NPM1", "NR2F1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PAK1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS2", "PDXK", "PEPD", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RAD54B", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REEP6", "RELA", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RREB1", "RSPRY1", "RTN2", "SACS", "SAMHD1", "SAR1B", "SARS", "SARS2", "SASS6", "SBDS", "SBF1", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SDHD", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", 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@@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 17.516666666666666 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1afff583b9131d5a44d740ddeb1afbf17c4e4bbc --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..343c5f65a515217c2d896fd760c77a5470393467 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,85 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosome 0.7051880598085949 2.955026491077533 0.0031264220443765 0.4308649416842859 0.0899975767145028 73 P18621,P08708,Q07020,P62847,P46782,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P36578,P60866,P62851,P62906,P61313,P62854,P62753,P50914,P62910,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9Y3U8 47 +Olfactory transduction 0.7979707549985039 2.5457043200725193 0.0109057520250568 0.8610745776839991 0.1402168117507307 2 Q13555 1 +Hedgehog signaling pathway 0.7763210022753694 2.4217185986816867 0.0154473072131948 0.9393244699345784 0.163559723433828 3 P49841 1 +Jak stat signaling pathway 0.7619593117571888 2.256747884608861 0.024023832884279 0.9874380154528892 0.1902653930285452 8 Q06124,O75925,P31751,P22681 4 +Regulation of autophagy 0.7317831527643808 2.125535072688431 0.033541990752691 0.9978475250213156 0.2415023334193755 7 Q9NT62,Q9Y4P1,O95352 3 +Base excision repair 0.7354179271214568 2.0277312497269206 0.0425876844362771 0.9996038845861211 0.2948378153280725 15 P09429,P27695,Q07864,P29372,P09874,P28340,P49005 7 +P53 signaling pathway 0.6904311570677033 1.773528223822732 0.0761412193674562 0.9999993558213164 0.4726006719359351 17 O96017,O14681,O95067,P42574,P42771,P14635,Q13535,Q13315,Q00534 9 +Tgf beta signaling pathway 0.6587076675911637 1.7055716950002633 0.0880878531058013 0.9999999381214516 0.5130353856185553 10 P28482,Q7Z3T8,Q13464,Q13616,O75116 5 +Cytosolic dna sensing pathway 0.6176475748470837 1.4603710079254513 0.1441881362946553 0.9999999999993268 0.5853130282481303 12 Q9NW08,O14802,O15111 3 +Sulfur metabolism 0.5726648761563629 1.4314296927818384 0.1523071035439311 0.999999999999879 0.5959843182153829 2 O43252 1 +Drug metabolism other enzymes 0.5928358659862336 1.3825048028034643 0.166816756809994 0.9999999999999946 0.6167316035529438 9 P00492,P12268,P04183,P11172,P49915,Q9BY32,P20839 7 +Type ii diabetes mellitus 0.5885594135481643 1.37902175120097 0.1678880476338569 0.9999999999999956 0.6167316035529438 8 P28482,O14654 2 +Non homologous end joining 0.5532224171710233 1.2155689951542377 0.2241491510458362 1.0 0.6928609727673127 7 P78527 1 +One carbon pool by folate 0.5655356855850477 1.2052436659633985 0.2281092499154089 1.0 0.6928609727673127 11 P00374 1 +Melanoma 0.5569898331579811 1.178327560019568 0.2386660446476189 1.0 0.6928609727673127 10 P36507,P28482,P31751,P42771,Q00534 5 +Prion diseases 0.5402070348456138 1.1687575186525028 0.2425013404685594 1.0 0.6928609727673127 6 P36507,P28482 2 +Acute myeloid leukemia 0.5534615658128609 1.1258420088131875 0.260232399249364 1.0 0.70075893121397 12 P28482,P42345,P31751,P40763,O15111 5 +Glioma 0.531769084828106 0.9824840850376516 0.3258614197007929 1.0 0.8261275429034188 14 P36507,Q13555,P28482,P42345,P31751,P42771,Q00534 7 +Nucleotide excision repair 0.5464294782804295 0.9507014695797842 0.3417559419822207 1.0 0.8367634031347311 23 Q07864,P35244,P35251,P28340,P18074,P49005 6 +Chronic myeloid leukemia 0.5386780818153941 0.9401830018852642 0.3471236992903135 1.0 0.8367634031347311 20 Q06124,P36507,P28482,P22681,P31751,P42771,Q00534,P11802,O15111 9 +Selenoamino acid metabolism 0.5167496510546556 0.937208306246628 0.3486514179728046 1.0 0.8367634031347311 12 Q9NZL9,O43709,P49903,P32929,P23526,O60294,Q7Z4G4,O43252 8 +Homologous recombination 0.4965824520971025 0.8357213474385865 0.4033116829418843 1.0 0.942806531552457 12 P35244,P28340 2 +B cell receptor signaling pathway 0.5058747825816765 0.8093585353770804 0.4183089454757769 1.0 0.9591178465854886 17 P36507,P49841,Q9UHD1,P28482,Q08209,P31751,Q9UDY8,O15111 8 +Mismatch repair 0.5053371949611177 0.7821454024556221 0.4341291266807527 1.0 0.967845202276099 19 P52701,P35244,P20585,P35251,P28340,P49005 6 +Colorectal cancer 0.4884637498889879 0.7797630808957776 0.4355303410242446 1.0 0.967845202276099 13 P52701,P49841,P28482,P42574,P31751,P20585 6 +Bladder cancer 0.4619233894126793 0.7534471435642872 0.4511812623903188 1.0 0.9860884758161188 7 P36507,P28482,P42771 3 +Tyrosine metabolism 0.4718952361583152 0.7476084725987788 0.4546963527374326 1.0 0.9860884758161188 10 Q7Z4G4,O60294,O43709 3 +Pancreatic cancer 0.4867767957797759 0.7284040558946372 0.4663662811994986 1.0 0.9913149277734354 16 P28482,P60953,P31751,P42771,P40763,Q00534,O15111 7 +Small cell lung cancer 0.4741380295038918 0.7255397989692578 0.4681209381152333 1.0 0.9913149277734354 12 O75925,Q00534,O15111,Q13309 4 +Non small cell lung cancer 0.4658508512572773 0.6705138786926448 0.5025302621439822 1.0 1.0 13 P36507,P28482,P31751,P42771,Q00534 5 +Wnt signaling pathway 0.4962991470912377 0.6645415585051015 0.5063437594221432 1.0 1.0 27 P49841,Q13555,P68400,Q13616,P17612,Q13464,O75116,Q08209,P19784,P61586,P67870,Q14738,Q9HCK8 13 +Cysteine and methionine metabolism 0.4716244969705813 0.6429062395884552 0.5202849404637537 1.0 1.0 17 P26358,Q13126 2 +Ubiquitin mediated proteolysis 0.4866825273133403 0.6156593577463269 0.5381193663884329 1.0 1.0 49 Q9UBT2,Q13616,O15344,O95071,P61081,Q15369,Q15386,P22314,P98170,Q14999,P49427,Q13309,Q8TBC4,Q7Z6Z7,Q9UJX5,Q05086,Q9NR09,O75925,P22681,P29372,Q13620,Q13618 22 +Fructose and mannose metabolism 0.4532128083301497 0.583473159761978 0.5595748203501674 1.0 1.0 15 P04075,Q00796,Q13614,P09972,Q96IJ6,P08237,P17858,Q9Y217 8 +Erbb signaling pathway 0.4547793861193813 0.5532728720591042 0.5800765740751161 1.0 1.0 18 Q16512,P36507,P49841,Q13555,P28482,P22681,P42345,P46109,P31751 9 +Cell cycle 0.4494437663384292 0.5033102875053758 0.6147461347018335 1.0 1.0 58 P49841,Q13616,P42771,Q13535,Q9UBD5,P33992,Q13309,P20248,Q00534,P78527,P30307,Q9UJX5,P14635,Q13315,P11802,O96017,O95067,O43913,Q14674,P53350 20 +Regulation of actin cytoskeleton 0.4518201018721575 0.4642821428284525 0.6424456161267043 1.0 1.0 53 P36507,Q14185,O75116,P46109,P62136,Q8TBX8,Q9Y2A7,Q7L576,P35241,O60610,Q96F07,Q8WUW1,Q9UQB8,Q14155,Q16512,P35580,Q13464,P28482,P35579,P60953,P46940,O00401 22 +Pentose phosphate pathway 0.422993644159576 0.4642197455474975 0.642490315785913 1.0 1.0 14 P04075,P06744,P11413,P09972,Q01813,P08237,P17858,P11908 8 +Long term potentiation 0.4112046776840229 0.4038028923117733 0.6863576694403357 1.0 1.0 15 P36507,Q13555,P28482,P17612,Q08209,Q15418,P62136 7 +Mtor signaling pathway 0.4060948209490318 0.3956111853203115 0.6923918842479055 1.0 1.0 14 P28482,P42345,Q15418,P31751,P62753,O60573 6 +Insulin signaling pathway 0.4429712260911094 0.3780682844153356 0.7053798681429335 1.0 1.0 40 P36507,P06730,P49841,P46109,Q13085,P31751,P62136,P49327,P06737,P17612,Q16822,O14654,Q9Y478,P42345,P62753,O60573,P11216,P13807,Q15382,P28482,P22681,Q93100 22 +Aminoacyl trna biosynthesis 0.4382541269624957 0.3766190613661259 0.7064567202110859 1.0 1.0 32 P47897,P49589,P26639,P07814,P41252,O43776,P23381,P54136,Q9NSD9,Q9P2J5,P26640 11 +T cell receptor signaling pathway 0.4314840370142497 0.3756931238868057 0.707145050386617 1.0 1.0 27 Q16512,P36507,P49841,Q9UHD1,P28482,P22681,P60953,Q08209,P31751,P19174,P61586,P11802,Q9UDY8,O15111 14 +Gnrh signaling pathway 0.4002560920942531 0.3730132135452678 0.7091386095825949 1.0 1.0 14 P36507,Q13555,P28482,P60953 4 +Renal cell carcinoma 0.4156211281537324 0.3596636456630079 0.7190986816961713 1.0 1.0 21 Q06124,P36507,Q16512,P28482,P60953,P31751,Q15369,Q9GZT9 8 +Rna polymerase 0.3871658509019646 0.3359727127267288 0.7368914437134015 1.0 1.0 13 Q9NW08,O14802 2 +Vascular smooth muscle contraction 0.3932829018710468 0.3251071236185583 0.7450999977014359 1.0 1.0 16 P36507,P28482,Q13464,P17612,O75116,P62136,P61586 7 +Inositol phosphate metabolism 0.3808041475723722 0.291861236918856 0.7703927221543998 1.0 1.0 15 O15357,Q13572,O00443,P42356,Q01968,Q8TBX8 6 +Oocyte meiosis 0.4202649743802461 0.2884318681124829 0.7730161765222923 1.0 1.0 42 Q9H2G2,O14965,P30307,O95067,Q13616,P17612,P28482,Q9UJX5,Q13555,Q08209,Q15418,P62136,Q14674,P14635,P53350,Q14738,Q99640 17 +Proteasome 0.4086747694314776 0.2576067842565241 0.7967103933134381 1.0 1.0 35 P49721,P28072,P60900,P25787,P20618,P55036,P28066,P49720,P61289,Q14997,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 17 +Chemokine signaling pathway 0.4051591272750635 0.2557418079973746 0.7981502102644726 1.0 1.0 32 Q16512,P49841,Q13464,P17612,P28482,O75116,P46109,P60953,P49407,P31751,Q8TEW0,P40763,O00401,O15111 14 +Dna replication 0.3990108085946001 0.2486855779767276 0.8036040055486566 1.0 1.0 29 P49005,Q07864,P25205,Q5TBB1,P35244,P18858,P35251,P09884,P33991,P28340,P33993,P49642,P33992 13 +Focal adhesion 0.402990607263335 0.2365492890447103 0.8130064651206037 1.0 1.0 36 Q16512,P17655,P49841,Q13464,P28482,Q14185,O75116,P46109,P60953,O60610,P31751,P62136,Q13418 13 +Adipocytokine signaling pathway 0.3761336779671181 0.2260203862837899 0.8211855646026289 1.0 1.0 21 Q06124,P42345,P31751,P40763,Q16822,O00221,O15111,O14654 8 +Adherens junction 0.3865670359287772 0.2204060299591743 0.825554949650626 1.0 1.0 27 P68400,P28482,Q9UQB8,P60953,P55196,Q8TEW0,P46940,P19784,P67870,O00401 10 +Starch and sucrose metabolism 0.3489047321990615 0.211992313906323 0.8321130306675923 1.0 1.0 13 P06744,P06737,O60701,P35573,P11216 5 +Endometrial cancer 0.3420241615349932 0.2112720968113703 0.8326749550100485 1.0 1.0 11 P36507,P49841,P28482,P31751 4 +Phosphatidylinositol signaling system 0.3472609809609931 0.1904996040022242 0.8489176534648266 1.0 1.0 15 O96017,O00443,P42356 3 +Natural killer cell mediated cytotoxicity 0.3502068446910247 0.1759803588049914 0.860309373030822 1.0 1.0 18 Q06124,P36507,Q16512,Q9UHD1,P28482,P42574,Q08209,P49327 8 +Purine metabolism 0.3641728404846036 0.1390516189193399 0.8894093592166403 1.0 1.0 56 P00492,P07741,P14618,O15067,P23921,Q9UKK9,P49643,P28340,O43252,Q9BUI4,P20839,P15531,Q9P2T1,P12268,Q07864,O43924,P09884,P49915,O14802,P49642,P49005,P31350,P22392,P31939,Q9NW08,Q06203,P30876,Q01433,P11908 29 +Pathogenic escherichia coli infection 0.3465129110451269 0.1339151038634626 0.8934697067096635 1.0 1.0 24 P04350,Q13464,Q9BUF5,O75116,Q13885,P60953,Q92974,O00401 8 +Neurotrophin signaling pathway 0.3565504093302238 0.1287032400192387 0.897592471571032 1.0 1.0 31 Q06124,P36507,P49841,Q13555,P28482,P60953,P46109,Q15418,P31751,P19174,P61586,Q9Y5V3,O14654 13 +Viral myocarditis 0.3125375495348384 0.1246724667175501 0.900782855677142 1.0 1.0 13 P35580,Q04637,P42574,P35579,O43432,Q14790 6 +Pyrimidine metabolism 0.3635222687388463 0.1223523465248528 0.9026199768395406 1.0 1.0 43 Q07864,P23921,P15531,P17812,P04183,P27708,Q9NW08,P28340,O14802,Q9BUI4,P49005 11 +Fc gamma r mediated phagocytosis 0.335726445929201 0.1211499070806217 0.9035723001243692 1.0 1.0 22 Q16512,P28482,P50570,P46109,P60953,O00429,P31751,O00401 8 +Prostate cancer 0.3189794066401816 0.1193441884085552 0.9050026763521613 1.0 1.0 16 P36507,P28482,P42345,P31751,O15111 5 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.2588059701492565 0.0943524216713641 0.9248292091349436 1.0 1.0 3 Q8NCH0,Q96L58 2 +Pathways in cancer 0.3398428297228881 0.0923176261681613 0.9264456845139476 1.0 1.0 59 P36507,P49841,P46109,P31751,P20585,P19174,P49327,P42771,Q15369,P52701,Q13309,P40763,P61586,Q00534,Q9GZT9,P42345,P42574,P11802,O15111,O75925,P28482,P22681,P60953,Q00653,Q14790 25 +Apoptosis 0.3217540580003796 0.0889954160766491 0.9290855531068802 1.0 1.0 24 P17655,P98170,Q9UHD1,P17612,P55212,P42574,Q08209,P31751,P49327,Q13315,Q14790,O15111 12 +Ether lipid metabolism 0.2583044471071352 0.0871051045595265 0.9305879679586946 1.0 1.0 4 P43034 1 +Progesterone mediated oocyte maturation 0.3267727661664513 0.084446054037534 0.9327017921973028 1.0 1.0 28 P30307,O95067,P28482,P17612,Q9UJX5,P31751,P20248,P14635,P53350 9 +Toll like receptor signaling pathway 0.3024898665969635 0.0824978937345786 0.9342507931833206 1.0 1.0 18 P36507,P28482,P31751,Q14790,Q9UHD2,O15111 6 +Fc epsilon ri signaling pathway 0.2835065152499284 0.0768553780550429 0.9387385956544256 1.0 1.0 13 P36507,P28482,P31751 3 +Vegf signaling pathway 0.2731590742310333 0.0641706572642449 0.9488343413359356 1.0 1.0 13 P36507,Q9UHD1,P28482,P60953,Q08209,P31751 6 +Axon guidance 0.3092750629243923 0.063947766732136 0.94901181773153 1.0 1.0 27 Q16512,P49841,Q13464,P28482,O75116,P60953,Q08209,Q00535,P61586,Q9BPU6 10 +Rna degradation 0.2991158040050989 0.0416244770804975 0.966798060260085 1.0 1.0 35 Q9UIV1,Q86TB9,Q96C86,Q8IZH2,A5YKK6,P26196,Q9Y2L1,Q6PGP7,Q96F86,Q15477 10 +Terpenoid backbone biosynthesis 0.2272074684107393 0.0349932564962861 0.9720851181180468 1.0 1.0 10 P04035 1 +Rig i like receptor signaling pathway 0.2328908403122464 0.0312257720363139 0.9750894868200046 1.0 1.0 14 Q13526,Q14790,Q9UHD2,O15111,Q14258 5 +Amyotrophic lateral sclerosis als 0.1897594190844704 0.0205422930796259 0.9836107741864928 1.0 1.0 13 P42574,Q9UER7,Q08209 3 +Mapk signaling pathway 0.271223230891267 0.0204081474582549 0.9837177844730428 1.0 1.0 49 Q16512,P36507,P28482,P17612,P42574,P51452,P46109,P60953,Q15418,Q99956,P31751,P21359,P49327,P49407,Q9UER7,O15111 16 +Epithelial cell signaling in helicobacter pylori infection 0.2330234791872487 0.0199970152868304 0.98404575354658 1.0 1.0 27 Q06124,Q16512,Q9Y5K8,P42574,O15111 5 +Gap junction 0.1908862103031061 0.0178700007637343 0.98574256111424 1.0 1.0 20 P04350,P36507,P28482,Q9BUF5,P17612 5 +Calcium signaling pathway 0.1740737243869735 0.0175435259527505 0.9860030094919374 1.0 1.0 18 Q9UHD1,Q13555,P17612,P46020,Q93100,Q08209,P19174 7 +Tight junction 0.2287221443404618 0.0153811121468698 0.9877281319688582 1.0 1.0 39 Q8NI35,P68400,P35579,P60953,P55196,P31751,Q8TEW0,P19784,P11802,P67870,Q15334,P63151 12 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b469cfe311a1847bb4319633ccda8ba0f5876dd2 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATR", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCKDHB", "BCL10", "BDH2", "BIRC6", "BLM", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BRCA1", "BRD8", "BRK1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "CA8", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC6", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CFL1", "CFL2", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP5", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "ESPL1", "EXO1", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA2", "GGCT", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKG", "ILK", "IMPDH1", "IMPDH2", "INPP4A", "INPPL1", "IQGAP1", "IQGAP2", "IQSEC1", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "KIDINS220", "L2HGDH", "LAMP1", "LAP3", "LARS", "LARS2", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LIG1", "LIG3", "LIG4", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAGED1", "MALT1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MCCC1", "MCCC2", "MCEE", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGAT1", "MGAT5", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NBN", "NCBP1", "NCKAP1", "NCL", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NF1", "NFKB2", "NFKBIE", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NNT", "NPC1", "NPC2", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC2", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS2", "PECR", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHF5A", "PHGDH", "PHKA1", "PHKB", "PI4KA", "PI4KB", "PIAS1", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNA1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTDSS1", "PTDSS2", "PTPN1", "PTPN11", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB13", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RALA", "RAPGEF2", "RARS", "RARS2", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHEB", "RHOA", "RIPK1", "RNASEH2A", "RNASEH2B", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEPHS1", "SETD2", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SLK", "SLTM", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORD", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAF6", "TAF6L", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBK1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TOMM40", "TP53", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TRA2A", "TRA2B", "TRAF2", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSPO", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR5", "UCK2", "UGCG", "UGDH", "UGP2", "UMPS", "UNC45A", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "USP8", "VAMP7", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS37B", "VPS45", "VPS4A", "VPS4B", "WARS", "WASF2", "WASL", "WBP11", "WDR61", "XAB2", "XIAP", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ACACA", "AFDN", "AGL", 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0.3338654522470946 0.026326738483471 6.758293817231167e-05 2.6808336119512787e-08 1.684277994401369e-16 +Infectious disease 127 359 4.791726731968498 1.6535201787792886e-06 93.33495145631068 341.3398058252427 -0.4428814065868994 0.6180619101849218 35.34489487789831 20.86156562558634 0.8677237015289705 0.3379145639376117 0.0006014366184734 2.080782487860734e-05 1.6213399644019946e-05 7.024205255899719e-18 +Metabolism of amino acids and derivatives 70 192 4.724331256162909 2.308738260792253e-06 65.06796116504854 189.54368932038835 -0.7041043859287429 0.4762547421245938 24.87493460436243 6.400131520234074 1.444416727789915 0.3613418136098282 0.0021460166218789 2.6509371136892093e-06 8.177862758087905e-08 1.1205621984976277e-18 +Cellular response to starvation 52 93 4.648033179506698 3.35115018978982e-06 41.6747572815534 88.34466019417475 -1.0303047421198284 0.3510932752390905 14.200404878998892 2.6553930524825846 2.028552953689577 0.3779284314527495 0.0289561601212906 8.278278561026824e-08 1.3181843397443454e-10 1.3566701161341907e-26 +Selenoamino acid metabolism 54 91 4.427860287923617 9.517251326585097e-06 45.359223300970875 88.94660194174757 -1.2269036973447986 0.3270935993226454 16.116146621354947 1.9650003351851577 2.2110932203759184 0.3833177831487697 0.0145949948181238 6.869934310483315e-08 8.082936800373577e-11 2.6168327684206713e-31 +Translation 73 218 4.291854280785363 1.7718721839532492e-05 77.70388349514563 217.4393203883495 -0.6292433087136844 0.5403058846506507 26.784191186963714 8.704909201038353 1.1001288839819463 0.3388062297179274 0.1612976563336116 0.000443797967744 5.476436123129359e-07 1.6180219383337261e-19 +Nonsense mediated decay nmd 52 87 3.897570716716376 9.716245454471915e-05 42.101941747572816 85.76941747572816 -1.1457400111181046 0.3421409039593034 15.03730946151162 2.536670214507658 2.1258465434199816 0.3829653082446096 0.0157117827609153 8.95450424800528e-08 1.3016031182363144e-10 1.6439874878982466e-29 +Cell cycle mitotic 83 262 3.81471983402881 0.0001363375222469 60.0873786407767 253.3398058252427 0.0612322611824096 0.8007165834866438 20.05579924659543 21.48619037105753 0.7351894504134832 0.305954015772947 0.0023530303459675 0.0210565860408059 0.0001914962654309 2.000527758260565e-08 +Srp dependent cotranslational protein targeting to membrane 49 93 3.8080234428966913 0.0001400819958989 36.76699029126213 90.33495145631068 -0.5167678337360311 0.4521019696915908 17.22196829379636 2.057296214960333 1.7319679229133378 0.3837080047653741 0.0149620345130709 7.51137443801525e-08 1.040650971565404e-11 4.289698104683873e-31 +Cell cycle 94 313 3.786525980819029 0.0001527681297419 69.92718446601941 298.80825242718447 -0.0681965595099257 0.757465080888165 23.36081564515137 27.011227975636626 0.766581491084473 0.3242843844652294 0.0022789660219912 0.0056632980039912 3.341579431061779e-05 2.3601890840505e-08 +Adaptive immune system 79 197 3.352683643280172 0.0008003212756624 46.463592233009706 186.4004854368932 0.1339433536175087 0.6962113214501324 20.006579857169463 16.487632898609263 1.0633527271457623 0.3569087738025599 0.222420088937715 0.2103609766591697 0.0383995985073363 0.0047746755413085 +Response of eif2ak4 gcn2 to amino acid deficiency 49 78 3.303012063666321 0.0009565227278423 39.550970873786405 76.03155339805825 -1.127048342201767 0.3185079045659907 13.761485019110056 1.5173669435319213 2.220942857496925 0.3803423215749384 0.0102936075696032 1.304754005243591e-09 7.698572160998068e-13 4.125390091074451e-33 +Eukaryotic translation elongation 53 78 3.193905112048932 0.0014036224481852 40.33980582524272 76.70873786407768 -1.170264854227122 0.3173586097479524 13.865899638243102 1.3501604935966776 2.213815111182405 0.3781772268307828 0.0088678833523326 1.1460992419244872e-08 3.1199912026085623e-12 4.0608899505615516e-33 +Dna repair 24 112 3.13132896238561 0.0017401711621469 34.28155339805825 109.91747572815534 -0.6396411249432735 0.4979590079265828 14.119921529340075 13.97285806698438 1.0437894098277785 0.3431329094235284 0.4099454941258983 0.5334796552648665 0.0116793066922601 0.0041807305355632 +Cell cycle checkpoints 54 147 2.935127842418344 0.0033341029060762 35.737864077669904 139.23300970873785 0.0395895335097635 0.683101356311267 14.89377348564558 13.286392691301824 0.9326100500655764 0.3317969957493373 0.0002070435540468 0.011773710169674 0.0001764282733553 0.0001352439817749 +Class i mhc mediated antigen processing presentation 49 117 2.887723225481316 0.0038804115465953 28.725728155339805 112.89320388349516 0.3223458068895866 0.6041405327539132 13.331837148395683 9.797624658989111 1.204887601525433 0.3771461993229535 0.0526273697980756 0.0233241225024621 0.0130403339440663 0.0049803096999295 +Separation of sister chromatids 40 108 2.7529743786314897 0.0059056517891913 27.25728155339806 104.59466019417476 0.1913519656937572 0.6759734454858931 10.904342253831215 7.99139528936842 0.9289444053822858 0.343574417926859 0.0105250285677211 0.0935981394072189 0.0120710526634541 0.0004445049735576 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 3 5 2.728949297466923 0.0063536471991461 1.924757281553398 5.359223300970874 0.336977121900856 0.5615787693388659 1.3244044968153963 1.0273386196659136 0.8252392613858638 0.3024273388948905 1.0 1.0 1.0 0.1659016353191164 +Flt3 signaling 2 5 2.671759494366906 0.0075454706931465 1.6966019417475728 4.674757281553398 0.1447448421401304 0.5151478334177053 1.1502165717541968 0.9558423770819222 0.9684926451060778 0.307151973986046 1.0 1.0 1.0 0.1423023069394473 +Insulin receptor signalling cascade 3 6 2.461870302230132 0.0138214637528406 2.145631067961165 5.944174757281553 0.1642968987021586 0.5898877371353451 1.5290568638920414 1.07680309318776 0.8198409216159995 0.2938567267019904 1.0 1.0 1.0 0.1905468417868487 +Metabolism of cofactors 0 5 2.450941317529544 0.0142483180088741 1.4004854368932038 5.589805825242719 0.8083917792774582 0.3609852370032988 1.1730384400465106 1.1078681360867626 1.0031936318469477 0.2887992775559558 0.0697581245313758 0.1349531130589082 0.3090006421698555 0.5276895149825147 +Metabolism of rna 114 472 2.44267560062706 0.0145788352325735 151.2597087378641 457.9538834951457 -1.0055551942090837 0.4350500122971218 47.911457858114936 22.758873431475507 1.2609348121138049 0.3457084215001203 0.0032836928653888 0.0001285362081583 1.149745604199971e-09 8.648058953198941e-23 +Fanconi anemia pathway 1 7 2.3443302169329545 0.0190612867726582 3.0606796116504853 6.766990291262136 -0.3782646002144036 0.4750285801239167 1.8730867323912268 1.719132110542402 0.9936526690495168 0.306110518181632 0.0128452267182733 0.0466281418945222 0.2179356607727124 0.5296970804404293 +Rho gtpase effectors 46 125 2.3015124012361965 0.021362685235831 31.6626213592233 114.50728155339806 -0.353257919880707 0.6313527865681305 13.414969935530763 11.72386353149821 0.7952262440246322 0.3244120789511128 0.1140816659961382 0.4225797932093376 0.5555357999723154 0.0043667772194004 +E2f enabled inhibition of pre replication complex formation 2 6 2.298379826923094 0.0215401806454431 1.3786407766990292 4.898058252427185 0.6103648495110074 0.4756502950255128 1.328306497955957 1.1821061163842537 0.8213823715403002 0.3012352436645789 0.0470522829573702 0.0921025797166938 0.0015031185668187 0.010684483318579 +Synthesis of pips at the early endosome membrane 3 6 2.288860728187416 0.022087445673772 1.7432098765432098 4.392592592592592 0.09275746576789 0.5623195883949448 1.3026978910929463 1.486214661212972 0.9436562313631665 0.3190248365483706 1.0 0.0100519320580488 0.0565188023636715 0.1818418904091173 +Diseases of signal transduction by growth factor receptors and second messengers 38 144 2.2616845816168323 0.0237168980111159 38.23543689320388 143.25485436893203 0.0760803095091799 0.6705657643193705 15.041864122024071 11.50835917079556 0.9951358349988204 0.3506422537450402 0.214696013821651 0.2163793399957447 0.2924338686779559 0.0017259573854256 +Maturation of sars cov 2 nucleoprotein 3 6 2.200558322293934 0.0277673068351904 2.412621359223301 4.985436893203883 0.0067238540290333 0.5371553195215879 1.444653995706506 0.9577388182984884 0.9451900366181616 0.3092790872936227 0.0607401038440192 0.1180585699575878 0.0385233102424958 0.1297945989547683 +Condensation of prometaphase chromosomes 8 11 2.1192890339619144 0.0340660478382257 4.740291262135922 9.682038834951456 -0.0253462500307974 0.547816752092043 2.6102910436658395 0.7810670560615536 0.9134052717438896 0.3114594049057282 1.0 1.0 9.854683287521486e-05 1.7452248386246545e-07 +Flt3 signaling in disease 2 6 2.114194951486486 0.0344986198981014 2.2354368932038833 6.092233009708738 -0.0477509828878908 0.6026489521188945 1.4532877201276568 1.2192779432877594 0.7593116607184317 0.2753414958221807 1.0 1.0 1.0 0.0892170338783466 +Transcriptional regulation by tp53 33 138 2.1040538748973816 0.0353737477329823 30.0995145631068 120.27912621359224 -0.2599212774798687 0.6794110221604227 12.49824452750087 14.325354371786895 0.5857864408569994 0.2753846693392611 0.0751636281055282 0.2163793399957447 0.0160471623493422 0.0064835321982433 +Activation of nima kinases nek9 nek6 nek7 2 5 2.0868290866985637 0.0369035868628357 1.9611650485436891 4.473300970873787 0.1472952164091358 0.5895977571949309 1.2991582793851182 0.6167293758276526 0.8032394649255438 0.2959385330608741 1.0 1.0 0.1583736196074974 0.0034775277607499 +Cyclin d associated events in g1 4 9 2.0615110113161825 0.0392543140591299 4.366504854368932 10.116504854368932 0.1222182547646903 0.5717022199186504 2.5273541207987025 1.6637247419470345 0.9055693104495058 0.3101665598109623 1.0 0.3530974878629287 0.2994428025832826 0.0664883963333954 +Egr2 and sox10 mediated initiation of schwann cell myelination 2 6 2.060267238143074 0.0393730001106553 1.5631067961165048 6.456310679611651 0.9405466898133904 0.3504222949879002 1.1919625891097876 1.444955732376159 0.8981851290078471 0.2877478182828594 1.0 1.0 1.0 0.6322714034398937 +Synthesis of pc 4 6 2.0432619168819484 0.0410265173690425 1.4975728155339805 5.177184466019417 0.9792901538510108 0.3349579960493364 1.1180313541111304 1.1575685242362048 0.9033750611806022 0.284045310792182 1.0 1.0 0.0990342687178565 0.0892170338783466 +Mismatch repair 5 12 2.01442349728174 0.0439650894314338 3.342233009708738 11.381067961165048 0.0625185193929023 0.487617128731856 2.731844368635289 1.3892551700174145 1.035220015060314 0.3024526770428278 0.0786913117950012 0.1515272625734178 0.0075105395483816 0.0001016217979366 +Negative regulation of fgfr1 signaling 2 6 1.965580419753366 0.0493470977164864 2.325242718446602 5.429611650485437 -0.070870283807868 0.5471783256995307 1.5124222484453904 1.0203734537447475 0.9049986192676228 0.3061293683898332 1.0 1.0 1.0 0.0470360579614364 +Negative regulation of fgfr3 signaling 2 6 1.965580419753366 0.0493470977164864 2.325242718446602 5.429611650485437 -0.070870283807868 0.5471783256995307 1.5124222484453904 1.0203734537447475 0.9049986192676228 0.3061293683898332 1.0 1.0 1.0 0.0470360579614364 +Negative regulation of fgfr4 signaling 2 6 1.965580419753366 0.0493470977164864 2.325242718446602 5.429611650485437 -0.070870283807868 0.5471783256995307 1.5124222484453904 1.0203734537447475 0.9049986192676228 0.3061293683898332 1.0 1.0 1.0 0.0470360579614364 +Negative regulation of fgfr2 signaling 2 6 1.965580419753366 0.0493470977164864 2.325242718446602 5.429611650485437 -0.070870283807868 0.5471783256995307 1.5124222484453904 1.0203734537447475 0.9049986192676228 0.3061293683898332 1.0 1.0 1.0 0.0470360579614364 +Spry regulation of fgf signaling 2 6 1.965580419753366 0.0493470977164864 2.325242718446602 5.429611650485437 -0.070870283807868 0.5471783256995307 1.5124222484453904 1.0203734537447475 0.9049986192676228 0.3061293683898332 1.0 1.0 1.0 0.0280386150660574 +Antigen processing ubiquitination proteasome degradation 40 91 1.963987836955125 0.0495315024522549 25.228155339805824 89.88592233009709 0.3040503636743611 0.5349081840989588 12.844717984151089 7.994482069951932 1.4235342488403817 0.383588489924638 0.031591823301381 0.0331776056462107 0.0080951492479709 0.010556073709219 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..35e927c391568048ca726b9c049aee3a871a2070 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 1390, + "title": "Average number of proteins per term", + "value": 20.223021582733814 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f120a490bd29c5d7d7296296e2ade8aaae5747fe --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cfb75f05fd2963671f30a90535a4fffe40c43706 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,629 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nervous system development 0.4937033633609645 7.437938409287702 1.0226871829280517e-13 1.4215490841690243e-10 1.4215490842699915e-10 222 P46782,P62847,Q14185,O75116,P46776,P51532,P62424,P62861,Q00535,P49721,P42766,Q14997,P32969,P46777,P62917,Q00169,P84098,P62854,P61313,P62753,O43242,P50914,P62910,P28066,O75832,Q13464,Q04637,P62277,P60953,P39023,P49720,P62899,Q9BPU6,P49207,P18621,P36507,P49841,P08708,P68400,Q15369,P17612,P25787,P20618,P35241,P61927,P46778,P27635,P36578,O94973,Q15418,P19784,Q13200,Q14155,P35580,P62266,Q9Y3U8,O00401,P28072,Q16850,P62701,P15880,Q9BUF5,P62081,P62269,P62841,P83731,Q13885,Q02878,P62280,P61586,P62244,P67870,P47914,P62750,P04350,P61247,Q96P70,P26373,P28482,P61513,Q7Z460,P04035,Q15334,Q07020,P61353,P40429,Q15008,P62241,Q02543,P46779,Q06124,P50570,P60866,P62851,P62906,Q00610,Q16512,P18124,P35579,P61254,P61289,Q9HAU5 102 +Developmental biology 0.4378254729134732 6.960312608525588 3.395184999139675e-12 4.719308527676223e-09 2.359654269402074e-09 270 Q15648,P46782,P62847,Q14185,O75116,P46776,P51532,P62424,P62861,Q00535,P49721,Q9ULK4,P42766,Q14997,P32969,P40763,P46777,P62917,Q92908,Q00169,P84098,P62854,P61313,P62753,O43242,O60271,P50914,P62910,P28066,O75832,Q13464,Q04637,Q96EK7,P62277,P60953,P39023,P49720,P62899,P49207,Q9BPU6,P18621,P36507,P49841,P08708,P68400,Q15369,Q92600,P17612,P25787,P20618,P35241,P61927,P46778,P27635,P36578,O94973,Q15418,P19784,O60244,P11802,Q13200,Q14155,P62266,Q9Y3U8,Q9Y2X0,P62701,P15880,P62081,P62269,P62841,P83731,Q02878,P62280,P67870,P47914,P62750,P04350,P61247,Q96P70,P26373,P28482,P61513,Q7Z460,P04035,Q15334,Q07020,P61353,P31751,P40429,Q15008,P62241,Q02543,P46779,Q06124,P50570,P60866,P62851,P62906,Q00610,Q16512,P18124,P35579,P61254,P61289,Q9HAU5 105 +Regulation of expression of slits and robos 0.5962203575814035 6.8448412273517505 7.656073657233752e-12 1.0641943716970172e-08 3.547314591184972e-09 123 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,Q15008,Q15369,P62241,Q02543,P49721,P15880,P25787,P62081,P62269,P62841,P42766,P83731,Q02878,Q14997,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P62851,P60866,P61313,P62906,P62753,O43242,P50914,P62910,P28066,O75832,P26373,P18124,Q04637,P62266,P62277,P61513,P39023,P49720,P62899,P61254,P61289,Q9Y3U8,Q9HAU5 61 +Signaling by robo receptors 0.5667788821403498 6.685907406722213 2.2949810546091818e-11 3.19002375406211e-08 7.975059512266908e-09 137 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,Q15008,Q15369,P62241,Q02543,P49721,P15880,P17612,P25787,P20618,P62081,P62269,P42766,P62841,P83731,Q14997,Q02878,P32969,P46779,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P62851,P60866,P61313,P62906,P62753,O43242,P50914,P62910,P28066,O75832,Q16512,P26373,P18124,Q04637,P62266,P62277,P60953,P61513,P39023,P49720,P62899,P61254,P61289,Q7Z460,Q9Y3U8,P49207,Q9HAU5 67 +Eukaryotic translation initiation 0.6290679383231014 6.428063842866322 1.2923946437200627e-10 1.7964284074292012e-07 3.592857137341774e-08 102 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,Q13144,P62701,P62241,Q02543,O15371,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P61927,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,Q14240,P50914,P62910,P26373,P18124,Q04637,P62266,P62277,P61513,P39023,P61254,P62899,O60841,Q14152,Q9Y3U8,P49207 57 +Influenza infection 0.491525823498535 5.374549408687588 7.677442947396764e-08 0.0001067107670677 1.4465088824670929e-05 127 P18621,P08708,P46782,P62847,Q07020,P09874,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,O14980,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,Q00610,P62906,P62753,O00629,Q5SRE5,P50914,P62910,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9Y3U8 52 +Rrna processing 0.4503161390769033 5.359934111732878 8.325230978127874e-08 0.0001157140200306 1.4465088824670929e-05 165 P18621,Q2NL82,P08708,P46782,P62847,Q07020,Q8IY37,P61353,P46776,O15091,P62424,P62861,P40429,P62701,P62241,Q02543,P15880,O43709,P62081,P62269,P62841,O75818,P42766,P83731,Q02878,P46779,Q9Y2L1,P32969,P46777,P62280,P46778,P27635,P62917,P78316,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,Q8IY81,P62753,P50914,P62910,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9H9L3,Q9Y3U8 57 +Cellular responses to stimuli 0.3336873933052441 5.07005844926651 3.976935484963763e-07 0.0005526413798008 6.1421559156817e-05 341 Q15648,P46782,P62847,P46776,P35244,P62424,P62861,Q13535,P49721,Q9Y5K8,P42766,P08243,Q14997,P20248,P32969,P40763,P46777,Q00534,O95070,P62917,Q0VDF9,P84098,P62854,P61313,P62753,P47755,O43242,Q92616,P50914,P62910,P28066,O75832,P62277,P39023,P49720,P62899,P49207,P18621,O75880,P08708,P49841,P68400,P42771,Q15369,Q14203,P25787,P20618,Q96L91,P61927,Q9Y2L1,Q14204,P46778,P27635,Q9NZ32,Q9GZT9,Q9HCE1,Q9UJX5,Q16881,P36578,Q53FT3,Q15418,P16402,Q15185,P19784,O43237,Q13315,P11802,Q9P0V3,P31689,Q13200,P63167,P62266,Q9Y3U8,P62701,P15880,Q14999,P62081,P62269,P62841,P83731,Q02878,Q13309,P62280,Q9UBS4,P67870,P47914,P62750,P04350,P17096,P61247,O75182,P26373,P28482,P61513,Q13616,Q07020,P61353,P40429,Q15008,P62241,Q02543,O14980,P46779,Q06210,P42345,P60866,P62851,P62906,Q5SRE5,Q13555,P18124,P61254,P61289 113 +Infectious disease 0.3307813978152292 4.791726731968498 1.6535201787792886e-06 0.0022957556614848 0.0002298393048504 359 P46782,P62847,Q14185,O75116,P46776,P62424,P62861,O75909,Q12873,Q9H3P2,P49721,P78362,Q14241,P42766,Q14997,P32969,P46777,Q08945,P62917,Q99873,Q8WUW1,O60942,P84098,P62854,P61313,P62753,O43242,P50914,P62910,P28066,O75832,Q13464,P62277,P60953,P39023,P49720,P62899,P49207,P18621,P36507,P08708,P49841,Q15369,P13639,P17612,P18615,P25787,P20618,P61927,Q14204,P46778,P27635,Q9BXS5,Q16881,P36578,O94973,Q15185,O43237,O00629,Q13200,Q96SB4,P63167,P62266,Q9Y3U8,Q9Y5B9,O00401,Q13618,O00410,P28072,P31146,P62701,Q9Y2A7,Q7L576,Q92759,P15880,Q9BUF5,P62081,P62269,P62841,P83731,Q14839,Q02878,Q13885,O94776,P62280,P62244,P62888,P47914,P18074,P62750,P04350,P17096,P61247,Q8WUX9,Q9NZQ3,Q9UQB8,P62942,P26373,P28482,P61513,P61803,Q99816,Q07020,P09874,P61353,P30419,P40429,Q15008,P62241,Q9UER7,Q02543,O14980,P46779,P18858,Q96F07,P49917,P60866,P62851,P62906,Q00610,Q5SRE5,P18124,P22681,P35579,P61254,P61289,Q99570 127 +Metabolism of amino acids and derivatives 0.3893087282647016 4.724331256162909 2.3087382607922535e-06 0.0032040060694472 0.0002917405620456 192 P18621,P08708,P61457,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,Q15008,Q13126,Q9P2J5,P62241,Q02543,P49721,P15880,P07814,P25787,P12277,P20618,P62269,P42766,P62841,P08243,Q14997,P83731,P32969,Q02878,P46777,P62280,P41252,P46778,P46779,P27635,P62917,P47914,P62750,Q14353,P61247,P84098,P62854,P36578,P62851,P60866,P61313,P62906,P62081,P62753,O43242,P50914,P62910,P28066,O75832,P47897,P26373,P18124,P62266,P62277,Q99707,P39023,P61513,P49720,P62899,P61254,P61289,Q9Y3U8,P49207 70 +Cellular response to starvation 0.6471503646574546 4.648033179506698 3.35115018978982e-06 0.0046472744160517 0.0003881748969841 93 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,Q9Y5K8,P62081,P62269,P62841,P83731,P42766,Q02878,P08243,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P42345,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,Q92616,P50914,P62910,Q9P0V3,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9Y3U8 52 +Selenoamino acid metabolism 0.6573557927444719 4.427860287923617 9.517251326585097e-06 0.0131419231070313 0.0009449270959967 91 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,Q9P2J5,P62241,Q02543,P15880,P07814,P62081,P62269,P62841,P83731,P42766,Q02878,P41252,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,P47897,P26373,P18124,P62266,P62277,P61513,P39023,P61254,P62899,Q9Y3U8,P49207 54 +Translation 0.3525365551780879 4.291854280785363 1.7718721839532492e-05 0.0243284165449543 0.0016419348904634 218 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,O43776,P62701,Q13144,Q9P2J5,P62241,Q02543,O15371,P15880,P13639,P07814,P62081,P62269,O76094,P62841,P42766,P83731,P61927,Q02878,P41252,P32969,P49770,P46777,P62280,P46779,P46778,P27635,P62917,P26640,P47914,P62750,P26639,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,Q14240,P50914,P62910,Q9HD33,P26641,P47897,Q05639,P26373,P18124,Q04637,P62266,P62277,P61513,P39023,P61254,P62899,P82675,O60841,Q14152,Q9NP92,Q9Y3U8,P60059,P49207 73 +Nonsense mediated decay nmd 0.6605220135753896 3.897570716716376 9.716245454471915e-05 0.1263385832613214 0.0079444595186565 87 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P63151,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,P26373,P18124,Q04637,P62266,P62277,P61513,P39023,P61254,P62899,Q9Y3U8,Q9HAU5 52 +Cell cycle mitotic 0.3150302546715045 3.81471983402881 0.0001363375222469 0.1726455477344508 0.010248103910505 262 P00374,P35244,Q6P1K2,Q9UBD5,P42695,P49721,P50748,P20248,Q14997,Q00534,Q07864,O43242,P28066,O75832,Q15003,Q14674,P49720,Q99996,P35251,P04818,P49841,P68400,Q92973,P42771,Q9BSJ2,P28340,Q6IBW4,P33992,Q14203,Q15021,P17612,P25787,P20618,Q14204,Q92674,Q9UJX5,Q8IXJ6,P19784,P14635,O43237,P11802,Q9BPX3,Q13200,P33993,P49005,P63167,O43913,Q9NTI5,Q96GX5,Q9H900,Q7Z5K2,Q14738,Q9UPP1,P28072,Q2NKX8,Q99661,Q9BUF5,Q13309,P67870,P63151,P04350,P30307,Q29RF7,Q8WUX9,Q9NTJ3,O95067,P28482,Q99986,Q7Z460,P53350,Q13616,P04183,P31751,Q15008,Q9P258,O14965,O14980,P18858,Q96CW5,Q5SRE5,Q9BT25,Q14008,P61289 83 +Srp dependent cotranslational protein targeting to membrane 0.5692831794698143 3.8080234428966913 0.0001400819958989 0.1769411823920936 0.010248103910505 93 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,P62081,P62269,O76094,P62841,P42766,P83731,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9Y3U8,P60059 49 +Cell cycle 0.2998482341796734 3.786525980819029 0.0001527681297419 0.1913296489002888 0.0106173850170666 313 P00374,P35244,Q6P1K2,Q13535,Q9UBD5,P42695,P49721,P50748,Q14997,P20248,Q9UH99,Q00534,O15084,Q07864,O43242,P28066,O75832,Q15003,Q14674,P49720,Q99996,P35251,P04818,P49841,P68400,Q92547,Q92973,P42771,Q9BSJ2,P28340,Q6IBW4,P33992,Q14203,Q15021,P17612,P25787,P20618,Q14204,Q92674,Q9UJX5,Q8IXJ6,P19784,P14635,O43237,Q13315,P11802,Q9BPX3,Q13200,P33993,P49005,O96017,P63167,O43913,Q9NTI5,Q96GX5,Q9H900,Q7Z5K2,Q14738,O00743,Q9UPP1,P28072,P54132,Q2NKX8,Q99661,Q9BUF5,Q15554,Q13309,P67870,P63151,P04350,P30307,Q29RF7,Q8WUX9,Q9NTJ3,O60921,O95067,P28482,Q99986,Q7Z460,P53350,Q13616,P04183,P31751,Q15008,Q9P258,Q9UER7,O14965,O14980,P18858,Q96CW5,Q5SRE5,Q9BT25,Q14008,P61289 94 +Adaptive immune system 0.3255546424716079 3.352683643280172 0.0008003212756624 0.6713927361435454 0.0444978629268311 197 Q9UII4,Q15386,P49721,Q14997,O94822,Q9Y6B6,Q9Y3I1,P47755,O43242,P28066,O75832,P60953,P49720,Q15436,Q92990,Q15369,Q14203,P17612,P25787,P20618,Q03518,Q9Y496,Q14204,Q9BXS5,Q9NZ32,Q5T4S7,Q7Z6Z7,Q9UJX5,O94973,O43237,O95486,Q9ULT8,Q9UDY8,Q13200,P63167,P52888,Q14738,Q13618,P28072,Q08209,P61081,Q99661,Q9BUF5,P49427,Q14999,Q13885,Q13309,Q10567,P04350,P62942,P25789,O15111,P09429,P53992,P60059,Q9UIQ6,Q13616,O95352,P31751,P19174,Q15008,O95782,O00487,O00221,O00139,P22314,P60900,P55735,Q8TBC4,Q06124,P42345,Q13404,P50570,Q05086,Q00610,Q16512,P29144,P61289,Q5T447 79 +Response of eif2ak4 gcn2 to amino acid deficiency 0.7001569770621365 3.303012063666321 0.0009565227278423 0.7355763898259924 0.0448198401246033 78 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P08243,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,Q92616,P50914,P62910,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9Y3U8 49 +Eukaryotic translation elongation 0.6871061726559302 3.193905112048932 0.0014036224481852 0.858067792026378 0.0460215646033456 78 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,P13639,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,P26641,Q05639,P26373,P18124,P62266,P62277,P61513,P39023,P61254,P62899,Q9Y3U8,P49207 53 +Activation of smo 0.938353548467826 3.1591345221259783 0.0015823843233415 0.889335954675995 0.0465161137573903 3 P49407 1 +Dna repair 0.3621522418390231 3.13132896238561 0.0017401711621469 0.9111623698805792 0.0465161137573903 112 P09874,Q99504,Q92547,P35244,P20585,Q13535,P28340,P52701,P18858,Q8N3C0,P18074,P78527,P49917,Q07864,Q13315,P49005,O96017,O75925,O60921,P27695,P29372,P35251,Q86WJ1,Q6P6C2 24 +Runx3 regulates p14 arf 0.9122649955237212 3.064137406638755 0.0021829862019293 0.9520534112293938 0.0523163934600312 2 P42771 1 +Signaling by mapk mutants 0.8937630558042342 2.9823707776834145 0.0028602536585733 0.9813414217921004 0.0614307937406695 2 Q99956 1 +Displacement of dna glycosylase by apex1 0.8934646374216602 2.9810452935552396 0.00287266301665 0.98166141326964 0.0614307937406695 2 P27695 1 +Cell cycle checkpoints 0.3384724124776488 2.935127842418344 0.0033341029060762 0.99036300598546 0.0642762916908291 147 P28072,Q92547,P35244,P42771,Q6P1K2,P54132,Q15008,Q13535,Q2NKX8,Q9UBD5,O00487,Q9P258,O00139,Q99661,P33992,P49721,O14980,P50748,P25787,P20618,P60900,P55735,P20248,Q14997,Q14204,Q92674,Q99741,P30307,Q14676,Q9UJX5,P25786,P14635,O43237,Q13315,O43242,Q13200,P33993,P28066,O75832,O96017,P25789,P63167,O60921,O43913,P43034,O95067,Q14008,P49720,P61289,Q9H900,Q7Z460,P53350,Q14738,Q99640 54 +Caspase activation via dependence receptors in the absence of ligand 0.8767532079976086 2.906477014119626 0.0036552375312011 0.993842525612012 0.0642762916908291 2 P42574 1 +Class i mhc mediated antigen processing presentation 0.3477839027907532 2.8877232254813157 0.0038804115465953 0.9955026377866396 0.0642762916908291 117 P28072,Q9UIQ6,Q15436,Q13616,O95352,Q92990,P61081,Q15008,Q15369,O00487,Q9UII4,Q15386,P22314,P49721,Q14999,P49427,P60900,P25787,P20618,P55735,Q03518,Q14997,Q13309,Q8TBC4,O94822,Q9Y6B6,Q9Y3I1,Q5T4S7,Q7Z6Z7,Q13404,Q9UJX5,Q05086,O95486,O43242,Q9ULT8,Q13200,P28066,O75832,P25789,O15111,P09429,P53992,P29144,P49720,P61289,P52888,Q5T447,P60059,Q13618 49 +Cd28 dependent pi3k akt signaling 0.8645180543121438 2.851454029733259 0.0043519778571652 0.9976713128758112 0.0642762916908291 2 P31751 1 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.8676102220922194 2.845051320027786 0.004440426822037 0.997941829033725 0.0642762916908291 3 Q9HCE1 1 +Regulation of runx1 expression and activity 0.8668656716417942 2.841682053357565 0.0044876221703626 0.9980730816561608 0.0642762916908291 3 Q9HCE1,Q00534 2 +Diseases of mismatch repair mmr 0.8660876235859175 2.838159759719949 0.0045374465582064 0.9982025802246396 0.0642762916908291 3 P20585 1 +Downregulation of erbb2 erbb3 signaling 0.8543718293046827 2.805547877909676 0.0050231118316337 0.9990878630275566 0.0664964328187703 2 P31751 1 +Separation of sister chromatids 0.3407729192991851 2.7529743786314897 0.0059056517891913 0.999734312875953 0.0747715341037854 108 P28072,Q6P1K2,Q15008,Q2NKX8,O00487,Q9P258,O00139,Q99661,P49721,O14980,Q9BUF5,P50748,P25787,P20618,Q13885,P60900,Q14997,Q14204,Q92674,P04350,Q9UJX5,Q29RF7,O43237,O43242,Q13200,P28066,O75832,P25789,P43034,P63167,Q14008,Q9NTI5,Q14674,P49720,P61289,Q9H900,Q7Z460,Q7Z5K2,P53350,Q14738 40 +Irs mediated signalling 0.8497671876680661 2.744005328498176 0.0060694552720144 0.9997887037767932 0.0747715341037854 4 Q06124,P31751 2 +Ngf stimulated transcription 0.842388059701494 2.7301595386454416 0.0063303682304876 0.999853308829986 0.0747715341037854 3 P50570,Q14839 2 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.8506336383899887 2.728949297466923 0.0063536471991461 0.9998580087830596 0.0747715341037854 5 Q06124,P31751,O14654 3 +Synthesis of pips at the late endosome membrane 0.8438339802926071 2.716741383805947 0.0065928100685495 0.99989838787632 0.0747715341037854 4 Q08AM6,Q99570,O00443 3 +Interleukin 7 signaling 0.832587287376902 2.706126696681161 0.0068073069261558 0.999924736061089 0.0747715341037854 2 P51532 1 +Signaling by leptin 0.8325872873768998 2.7061266966811495 0.006807306926156 0.999924736061089 0.0747715341037854 2 Q06124 1 +Transcriptional regulation of pluripotent stem cells 0.8284094300208895 2.6869248556925354 0.0072113173971377 0.9999572460100932 0.0748039640449365 2 P40763 1 +Flt3 signaling 0.8382573749738329 2.671759494366906 0.0075454706931465 0.999973223171731 0.0772310161770777 5 Q06124,P31751 2 +Regulation of bach1 activity 0.8158810430653067 2.607720616607708 0.0091147313856976 0.9999970318429904 0.0881125590068789 3 Q13309 1 +Mapk1 erk2 activation 0.809253731343285 2.576834455611341 0.0099709691219822 0.9999991074710692 0.0925726224638515 3 Q06124,P28482 2 +Wnt mediated activation of dvl 0.8080597014925408 2.5712580615387624 0.0101329788671389 0.999999289066598 0.0925726224638515 3 P67870,P19784 2 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.8092125711227492 2.555915536106382 0.0105908823155762 0.9999996263092154 0.0949762994751677 4 P28482,P31751 2 +Synthesis of diphthamide eef2 0.7985074626865681 2.5265181701394575 0.011519942913845 0.999999898749479 0.1019918512754435 3 Q9BQC3,Q9H2P9 2 +Prolactin receptor signaling 0.7918110721537184 2.495017616200799 0.0125950877064422 0.9999999776928524 0.1066490758717881 3 Q13616 1 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.783049835869877 2.475624796702391 0.0133003269962863 0.9999999917371828 0.110044372171655 2 Q00534 1 +Insulin receptor signalling cascade 0.7975928445818347 2.4618703022301314 0.0138214637528406 0.999999996035312 0.1116967128863285 6 Q06124,P28482,P31751 3 +Metabolism of rna 0.2452828991944108 2.44267560062706 0.0145788352325735 0.9999999986372342 0.115797605561584 472 Q2VPK5,P67809,P62847,P46782,O43592,P46776,O15091,P62424,P62861,Q8IYB3,P49721,Q9UET6,O75818,P42766,Q14997,P32969,P46777,P62917,Q92499,O60942,P84098,P62854,P61313,Q8IY81,O75691,P62753,O43242,P50914,P62910,P09012,P28066,O75832,Q04637,P62277,P39023,P49720,P62899,Q9Y3Y2,P49207,P18621,P08708,P62314,Q96FX7,Q8IZH2,O60294,Q9UBP6,Q5TAX3,P25787,Q9Y2L1,Q7L014,Q9UBB9,P46778,P27635,O43290,Q86TB9,P36578,Q99575,Q9UJA5,Q7Z4G4,Q15477,O60231,P62266,Q9Y3U8,Q96C86,Q2NL82,Q8IY37,A5YKK6,P62701,Q96BP3,P15880,P62081,P62269,P62841,P83731,Q02878,P62280,P78316,P47914,P63151,P18074,P62750,P57678,P61247,Q14240,P26373,P61513,Q9H9L3,Q9UIV1,Q07020,P61353,P40429,Q15008,P62241,Q02543,P57081,O14980,O43709,P07814,P26196,P46779,Q6PGP7,Q8TEA1,Q8WUA2,Q96F86,P60866,P62851,P62906,Q5SRE5,Q92917,P18124,P51003,P61254,P61289,Q9HAU5 114 +Nostrin mediated enos trafficking 0.7726051924798505 2.4262335924689475 0.0152564468987481 0.9999999994761906 0.1184718502193293 2 P50570 1 +Phosphorylation of emi1 0.7753895643317794 2.4172918029919463 0.0156364762865193 0.9999999996936894 0.1194214397706695 3 P14635 1 +Calcineurin activates nfat 0.7675320799761179 2.402143828011264 0.0162992984772072 0.9999999998798998 0.1238034146629402 2 P62942 1 +Aryl hydrocarbon receptor signalling 0.7667923250620539 2.376329236239904 0.01748585291536 0.9999999999775638 0.1292611698727144 3 O00170 1 +Interleukin 6 family signaling 0.7685871654487602 2.3633932144822585 0.0181084445384478 0.999999999990704 0.13011702501348 4 Q06124,P22681 2 +Interleukin 6 signaling 0.7685871654487602 2.3633932144822585 0.0181084445384478 0.999999999990704 0.13011702501348 4 Q06124,P22681 2 +Erbb2 regulates cell motility 0.7555953446732344 2.3452049622322337 0.0190166224950429 0.9999999999974314 0.1338140839090657 2 O60610 1 +Fanconi anemia pathway 0.7765962878694752 2.3443302169329545 0.0190612867726582 0.9999999999975888 0.1338140839090657 7 P35244 1 +Rho gtpase effectors 0.3147678375579134 2.3015124012361965 0.021362685235831 0.999999999999908 0.14207718888902 125 O75116,Q13526,Q6P1K2,P07737,Q9Y2A7,Q2NKX8,Q7L576,Q9P258,O00139,Q99661,P60660,O14980,Q15058,Q9BUF5,P61160,P50748,Q13885,O60610,Q14204,P61586,Q92674,Q96F07,Q8WUW1,P04350,P30307,Q9NZQ3,Q16513,O43237,Q9UQB8,P43034,Q16512,P63167,Q14008,P35580,Q13464,P28482,P35579,P60953,Q15334,P46940,Q9H900,Q7Z460,Q99570,P53350,Q14738,O00401 46 +E2f enabled inhibition of pre replication complex formation 0.7635192892194353 2.298379826923094 0.0215401806454431 0.9999999999999284 0.1425754814150761 6 Q9UBD5,P14635 2 +Synthesis of pips at the early endosome membrane 0.7615534529361344 2.288860728187416 0.022087445673772 0.9999999999999672 0.1445011976733917 6 Q08AM6,Q99570,O00443 3 +Myoclonic epilepsy of lafora 0.7436586093703399 2.2879061123370144 0.0221429892837643 0.9999999999999696 0.1445011976733917 2 P46976 1 +Diseases of signal transduction by growth factor receptors and second messengers 0.306274369314748 2.2616845816168323 0.0237168980111159 0.9999999999999968 0.1519193006241991 144 P36507,P49841,Q9H6R7,Q13616,O95352,P31751,P21359,Q15008,Q14203,P49721,P25787,Q99956,Q14997,P40763,Q06124,P42345,O00203,P49407,Q92614,Q00610,P62753,O43242,Q13501,P62942,P26641,Q9NR09,P28066,O75832,O15111,Q13555,P28482,P22681,P31939,P35579,P49720,P61289,Q99996,P46940 38 +Fasl cd95l signaling 0.7353028946583011 2.2475836165559886 0.0246027532364627 0.9999999999999992 0.1554446681758329 2 P49327 1 +Interleukin 20 family signaling 0.7386003013296732 2.240706550205669 0.0250450895401179 0.9999999999999996 0.1567840649666751 3 Q06124 1 +Dcc mediated attractive signaling 0.7397696700278387 2.22433966218763 0.0261256001064564 1.0 0.1597654576691586 4 Q14185,P60953 2 +Maturation of sars cov 2 nucleoprotein 0.7434088815116837 2.200558322293934 0.0277673068351904 1.0 0.165650457085471 6 P78362,Q96SB4,Q99873 3 +Interleukin 2 family signaling 0.7316355656954693 2.1847206170745803 0.0289093375690587 1.0 0.1702710983940326 4 O15357 1 +Synthesis of ip3 and ip4 in the cytosol 0.7285756942370912 2.1697751772893867 0.0300238817084204 1.0 0.1703606422448805 4 Q01968,Q13572,O15357 3 +Downstream signaling of activated fgfr4 0.7239160852439643 2.169284272646716 0.030061108509809 1.0 0.1703606422448805 3 Q06124 1 +Downstream signaling of activated fgfr3 0.7239160852439643 2.169284272646716 0.030061108509809 1.0 0.1703606422448805 3 Q06124 1 +Downstream signaling of activated fgfr2 0.7239160852439643 2.169284272646716 0.030061108509809 1.0 0.1703606422448805 3 Q06124 1 +Downstream signaling of activated fgfr1 0.7239160852439643 2.169284272646716 0.030061108509809 1.0 0.1703606422448805 3 Q06124 1 +Signaling by erythropoietin 0.7227611404904624 2.1636443184594807 0.0304916574468898 1.0 0.1703606422448805 3 P46109 1 +Vitamin b2 riboflavin metabolism 0.7159056997911029 2.1533062654363535 0.0312946167109977 1.0 0.1703606422448805 2 Q969G6 1 +Condensation of prometaphase chromosomes 0.743401153996639 2.1192890339619144 0.0340660478382257 1.0 0.1800448916164783 11 Q15003,O95067,Q15021,P19784,P14635,Q9NTJ3,P67870,Q9BPX3 8 +Flt3 signaling in disease 0.7258171217494063 2.114194951486486 0.0344986198981014 1.0 0.1816404608271249 6 Q06124,Q92614 2 +Nuclear receptor transcription pathway 0.7153017627963099 2.1046798664220363 0.0353191842105431 1.0 0.1838483355869525 4 P10589 1 +Transcriptional regulation by tp53 0.3009307371007894 2.1040538748973816 0.0353737477329823 1.0 0.1838483355869525 138 O75880,Q9UIV1,Q92547,A5YKK6,P35244,P31751,P42771,P49327,Q00535,O75909,Q12873,Q13535,Q9H3P2,Q15369,Q9UER7,Q9NVI1,O14965,Q14241,Q14839,P20248,Q9NYV4,Q08945,P67870,P18074,Q9HCE1,P30307,P55212,P42345,P19784,P14635,Q13315,O96017,O60921 33 +Interleukin 37 signaling 0.7147785674254399 2.102105495295456 0.0355440356170642 1.0 0.1838483355869525 4 Q06124,Q12923 2 +Activation of nima kinases nek9 nek6 nek7 0.7160616439350423 2.0868290866985633 0.0369035868628357 1.0 0.1858550207947165 5 O95067,P14635 2 +Cyclin d associated events in g1 0.7257029067582408 2.0615110113161825 0.0392543140591299 1.0 0.1933868203314875 9 Q00534,P63151,Q13309,P42771 4 +Synthesis of pips at the er membrane 0.7063916377795635 2.060749547718262 0.0393269399933953 1.0 0.1933868203314875 4 P42356,O95248 2 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.7149064768850433 2.060267238143074 0.0393730001106553 1.0 0.1933868203314875 6 P04035,P51532 2 +Synthesis of pc 0.7114773950950346 2.0432619168819484 0.0410265173690425 1.0 0.1993946123880037 6 P67870,P19784,Q9NQZ5,P35790 4 +Assembly of the hiv virion 0.6881527902118639 2.0168155242006227 0.0437147682697329 1.0 0.2095294065342373 2 Q99816 1 +Mismatch repair 0.7253211932774429 2.0144234972817396 0.0439650894314338 1.0 0.2100050663563335 12 P52701,P35244,P20585,P28340,P49005 5 +Metabolism of ingested semet sec mesec into h2se 0.6800954938824221 1.9768456221428712 0.0480590829931535 1.0 0.220361809182864 2 P32929 1 +Tight junction interactions 0.6830460396157437 1.9677602708711237 0.0490956274015712 1.0 0.2207375382820588 3 Q8NI35 1 +Negative regulation of fgfr1 signaling 0.6958803875562919 1.965580419753366 0.0493470977164864 1.0 0.2207375382820588 6 Q06124,P28482 2 +Negative regulation of fgfr3 signaling 0.6958803875562919 1.965580419753366 0.0493470977164864 1.0 0.2207375382820588 6 Q06124,P28482 2 +Negative regulation of fgfr4 signaling 0.6958803875562919 1.965580419753366 0.0493470977164864 1.0 0.2207375382820588 6 Q06124,P28482 2 +Negative regulation of fgfr2 signaling 0.6958803875562919 1.965580419753366 0.0493470977164864 1.0 0.2207375382820588 6 Q06124,P28482 2 +Spry regulation of fgf signaling 0.6958803875562919 1.965580419753366 0.0493470977164864 1.0 0.2207375382820588 6 Q06124,P28482 2 +Antigen processing ubiquitination proteasome degradation 0.434276776881039 1.9639878369551251 0.0495315024522549 1.0 0.2207375382820588 91 P28072,Q9UIQ6,Q13616,O95352,Q92990,P61081,Q15008,Q15369,O00487,Q9UII4,Q15386,P22314,P49721,Q14999,P49427,P60900,P25787,P20618,Q14997,Q13309,Q8TBC4,O94822,Q9Y3I1,Q5T4S7,Q7Z6Z7,Q13404,Q9UJX5,Q05086,O43242,Q9ULT8,Q13200,P28066,O75832,P25789,P29144,P49720,P61289,P52888,Q5T447,Q13618 40 +Polb dependent long patch base excision repair 0.6938719227427897 1.9555381301576291 0.0505195873701886 1.0 0.2236376638361856 6 P27695,P09874 2 +Smad2 smad3 smad4 heterotrimer regulates transcription 0.6888468256548961 1.951667653003322 0.0509776753908699 1.0 0.2249491072803467 5 O75909 1 +Pexophagy 0.6741525179259542 1.9233937601566675 0.0544306173863617 1.0 0.2370960407838679 3 Q13315 1 +Synthesis of udp n acetyl glucosamine 0.6782551158373504 1.9208245218874016 0.0547538338788644 1.0 0.2370960407838679 4 Q06210,Q9UJ70 2 +Cdc6 association with the orc origin complex 0.6817901567314097 1.916351324216948 0.0553203921108222 1.0 0.2378866253142998 5 Q9UBD5 1 +Cd163 mediating an anti inflammatory response 0.666965085049227 1.911389526354483 0.0559545416563822 1.0 0.2393132704688348 2 P35579 1 +Dna replication initiation 0.6799103005557638 1.906925167059237 0.0565302786479913 1.0 0.2402969031214309 5 P49642,P09884,Q07864 3 +Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.6686567164179149 1.8958894794177452 0.0579746603853226 1.0 0.2427252347457784 3 Q06124,Q6SZW1 2 +Dna damage reversal 0.6673496806636675 1.843752127007723 0.0652192724241818 1.0 0.2674182556625743 5 Q6P6C2 1 +Clec7a inflammasome pathway 0.6563183494611733 1.8339039112843056 0.0666682588891469 1.0 0.2711881939911592 3 Q9UDY8 1 +S phase 0.3940399009612517 1.8257943161799848 0.0678812497968448 1.0 0.272424589217291 94 P49841,Q13616,P35244,P31751,Q15008,P28340,Q9UBD5,P33992,P49721,P25787,P20618,Q14997,P20248,Q13309,P18858,Q07864,Q9UJX5,Q29RF7,O43242,P11802,Q13200,P28066,O75832,P49005,O43913,Q9NTI5,P49720,P61289,P35251,Q7Z5K2 30 +Rna polymerase iii transcription initiation from type 3 promoter 0.667463105237604 1.822703398685956 0.0683483252789636 1.0 0.272424589217291 6 Q9NW08,O14802 2 +Rna polymerase iii chain elongation 0.667463105237604 1.822703398685956 0.0683483252789636 1.0 0.272424589217291 6 Q9NW08,O14802 2 +Signaling by pdgf 0.6671692734516896 1.821217475665616 0.0685738050311353 1.0 0.272424589217291 6 Q06124,P46109,P40763 3 +Downstream signal transduction 0.6671692734516896 1.821217475665616 0.0685738050311353 1.0 0.272424589217291 6 Q06124,P46109,P40763 3 +Signaling by ntrk2 trkb 0.6616730593413819 1.8150961024918977 0.0695091420548554 1.0 0.2744821234552531 5 Q06124,Q00535 2 +Bmal1 clock npas2 activates circadian gene expression 0.6516406818219649 1.8103209474869617 0.0702460304393879 1.0 0.275058135130695 3 Q15648 1 +Synthesis of ip2 ip and ins in the cytosol 0.6489552238806039 1.7967618241339247 0.0723734393598456 1.0 0.2810750650250477 3 Q01968,Q96PE3 2 +Polo like kinase mediated events 0.6643379892845981 1.7876453545000244 0.073833243216697 1.0 0.2810750650250477 7 O95067,P30307,P14635 3 +Uptake and function of diphtheria toxin 0.6516430121538245 1.7868967800314834 0.0739541730459596 1.0 0.2810750650250477 4 P13639 1 +Nr1h2 and nr1h3 mediated signaling 0.6558216513297211 1.785491357139779 0.0741816520011204 1.0 0.2810750650250477 5 P49327,Q9HCE1 2 +Smac xiap regulated apoptotic response 0.6465563967783913 1.7846377232585593 0.0743200984221146 1.0 0.2810750650250477 3 P42574 1 +Activation of caspases through apoptosome mediated cleavage 0.6465563967783913 1.7846377232585593 0.0743200984221146 1.0 0.2810750650250477 3 P42574 1 +Interleukin 3 interleukin 5 and gm csf signaling 0.6668261760302119 1.7818352632160357 0.0747760999054141 1.0 0.2816769075027794 8 Q06124,O15357,P17612,P22681 4 +G2 m dna replication checkpoint 0.6464711445086266 1.7607034140781714 0.078288614608291 1.0 0.2901897981480655 4 P14635 1 +Purine salvage 0.6564208569675365 1.7473771827512872 0.0805719327315221 1.0 0.2962830330603593 7 P00492,Q9P2T1,Q01433 3 +Ret signaling 0.6469032275733179 1.7402443146254165 0.0818161273470376 1.0 0.2992747816115326 5 Q06124,P19174,P17612 3 +Rna polymerase iii transcription initiation from type 1 promoter 0.662009070446837 1.7062752131910848 0.0879568507894716 1.0 0.3131922863590756 11 Q9NW08,Q9BUI4,Q12789,O14802 4 +Constitutive signaling by akt1 e17k in cancer 0.6431079976435248 1.6989917951912152 0.0893207295597728 1.0 0.3141534997096643 6 O15111,P49841,P31751,P42345 4 +Pyrimidine salvage 0.629552238805976 1.6983786338098468 0.0894363220642617 1.0 0.3141534997096643 3 Q08623,P04183 2 +Mitotic g2 g2 m phases 0.3935843542002192 1.6973536563815614 0.0896298186517481 1.0 0.3141534997096643 93 P28072,Q13616,Q9Y570,Q9BSJ2,Q15008,O00487,Q14203,P49721,O14965,O14980,Q9BUF5,P17612,P60900,P25787,P20618,Q13885,Q14997,P20248,Q14204,P63151,P04350,P30307,P07437,Q96CW5,P14635,O43242,Q9BT25,Q13200,P28066,O75832,P25789,P43034,P63167,O95067,Q14008,P49720,P61289,Q99996,Q7Z4H7,Q7Z460,P53350,Q99640 42 +Epha mediated growth cone collapse 0.6501792107213222 1.6968455968375051 0.0897258556724724 1.0 0.3141534997096643 8 P35580,Q13464,P35579,O75116,P61586 5 +Deubiquitination 0.3545624348602642 1.6914721224065663 0.090746667768863 1.0 0.3169293170822103 97 Q70CQ2,Q9UPT9,Q93008,Q15008,Q9Y4A5,P49721,Q86UV5,P25787,P20248,Q14997,Q13309,Q8NB78,Q6GQQ9,P49407,Q96RU2,O43242,Q96FW1,P28066,Q14258,P40818,P49720,P61289,P85037 23 +Tgf beta receptor signaling activates smads 0.6502974315569511 1.679502094895795 0.0930542309285247 1.0 0.3213222506393232 9 O14980,P22681,P62136,P61081,P62942 5 +Trif mediated programmed cell death 0.6207102357505171 1.6778761358273997 0.0933712821653576 1.0 0.3213222506393232 2 Q14790 1 +Tlr3 mediated ticam1 dependent programmed cell death 0.6207102357505171 1.6778761358273997 0.0933712821653576 1.0 0.3213222506393232 2 Q14790 1 +Signaling by csf3 g csf 0.6427520493229792 1.6775986744833686 0.0934254717581735 1.0 0.3213222506393232 7 Q06124,Q15369 2 +Cytochrome c mediated apoptotic response 0.6341679119963402 1.6753856197236374 0.0938585962261076 1.0 0.3213222506393232 5 P42574 1 +Synthesis of pips at the golgi membrane 0.6474402814934151 1.6648252588147816 0.0959476230582065 1.0 0.3252858440266028 9 P42356,Q01968,Q08AM6,O00443 4 +Vxpx cargo targeting to cilium 0.6435259272159631 1.662750248526767 0.0963624392499575 1.0 0.3258973006263772 8 Q8TAG9,Q96KP1,Q92538 3 +Regulation of pten localization 0.616830796777076 1.658103676757355 0.0972965419147202 1.0 0.3282577506346144 2 P98170 1 +Synthesis of pyrophosphates in the cytosol 0.6150402864816417 1.648969210939398 0.0991539425502465 1.0 0.3321059762526331 2 Q13572 1 +Oncogene induced senescence 0.6352301106246431 1.639071540173562 0.1011983613702571 1.0 0.3357177143309247 7 Q9HCE1,Q00534,P42771 3 +Akt phosphorylates targets in the cytosol 0.6243650111396075 1.6252786699031898 0.1041031942557753 1.0 0.3428991469562267 5 O15111,P49841,P31751 3 +Tp53 regulates transcription of caspase activators and caspases 0.6147595443892064 1.6229187572503054 0.1046067732537443 1.0 0.3437432974532025 3 P55212 1 +Raf independent mapk1 3 activation 0.6283395681725885 1.6037055732675862 0.1087789668383178 1.0 0.3541048335017842 7 Q06124,P28482,Q99956 3 +Cyclin a b1 b2 associated events during g2 m transition 0.6438696949559213 1.596827764241881 0.1103041052442055 1.0 0.3573955857562836 12 P30307,O95067,O14980,P20248,P14635,P53350,P63151,Q99640 8 +Regulation of mecp2 expression and activity 0.6331890055191369 1.5914452081546644 0.1115094170700441 1.0 0.3604606737845612 9 Q9HCE1,Q13555,P42858 3 +Rna polymerase iii transcription termination 0.6234731370726312 1.5786895287334044 0.1144072878013675 1.0 0.3647388303759195 7 Q9NW08,O14802 2 +M phase 0.2518853973114583 1.5631719026468285 0.1180121670043998 1.0 0.3733499793656391 199 Q9UPP1,P68400,P28072,Q92973,Q6P1K2,Q9BSJ2,Q15008,Q2NKX8,Q9P258,Q6IBW4,Q99661,P42695,Q14203,P49721,O14980,Q15021,P17612,P50748,P25787,P20618,Q9BUF5,Q14997,Q14204,Q92674,P67870,P63151,P04350,Q9UJX5,Q29RF7,Q8WUX9,Q8IXJ6,Q96CW5,P19784,P14635,O43237,Q9NTJ3,Q5SRE5,O43242,Q9BT25,Q9BPX3,Q13200,P28066,O75832,P63167,Q15003,O95067,P28482,Q14008,Q9NTI5,Q14674,P49720,Q96GX5,Q99996,Q99986,Q9H900,Q7Z460,P61289,Q7Z5K2,P53350,Q14738 60 +Apoptotic factor mediated response 0.6203165670465909 1.562446978692402 0.1181827272812094 1.0 0.3733499793656391 7 P42574,P42771 2 +Formation of apoptosome 0.6019081884896132 1.5570833094247614 0.1194507071992239 1.0 0.3750846838166935 3 P28482 1 +Mitotic prometaphase 0.3542656194327714 1.5517722409696202 0.1207167301959122 1.0 0.3758553209662106 96 P68400,Q6P1K2,Q9BSJ2,Q2NKX8,Q9P258,Q99661,Q14203,O14980,Q15021,P17612,P50748,Q9BUF5,Q14204,Q92674,P67870,P04350,Q29RF7,Q96CW5,P19784,P14635,O43237,Q9NTJ3,Q9BT25,Q9BPX3,P63167,Q15003,O95067,Q14008,Q9NTI5,Q99996,Q9H900,Q7Z460,Q7Z5K2,P53350,Q14738 35 +Gpvi mediated activation cascade 0.6099103767365363 1.551138144817926 0.1208685816344576 1.0 0.3758553209662106 5 Q06124,P60953 2 +Rrna processing in the mitochondrion 0.6070849408017064 1.536614067856482 0.1243878455207718 1.0 0.3842202339419397 5 Q8WVM0,O15091 2 +Traf6 mediated induction of tak1 complex within tlr4 complex 0.5917636526409958 1.5297641374889304 0.1260751214674562 1.0 0.3882864131862314 2 Q6SZW1 1 +Rna polymerase iii transcription 0.6308220074839485 1.5290061473488328 0.12626291997135 1.0 0.3882864131862314 12 Q9NW08,Q9BUI4,Q12789,O14802 4 +Signaling by scf kit 0.6120296286582152 1.5197500701214166 0.1285738022650029 1.0 0.3936510686087093 7 Q06124,P22681 2 +Wnt ligand biogenesis and trafficking 0.6010042734585638 1.5053252533815755 0.1322404757026065 1.0 0.3997240533925743 5 Q96QK1,O60493,O75436 3 +Pcna dependent long patch base excision repair 0.641508513525265 1.50516064580358 0.1322827802594131 1.0 0.3997240533925743 18 P27695,Q07864,P35244,P35251,P28340 5 +Traf3 dependent irf activation pathway 0.589313048880076 1.492346136329321 0.1356084277606224 1.0 0.4062491882017116 3 Q14258 1 +Met receptor recycling 0.5891347647409042 1.491428449811224 0.135849043373172 1.0 0.4062491882017116 3 P46109 1 +Met activates ras signaling 0.5931199615910253 1.4878939125263089 0.1367788733408759 1.0 0.4062491882017116 4 Q96S59,Q96P70 2 +Nucleotide salvage 0.616357487215343 1.4867813536445662 0.1370725678176998 1.0 0.4062491882017116 10 P00492,P07741,P04183,Q9P2T1,Q01433 5 +Hdms demethylate histones 0.6107602163197812 1.4754727728349102 0.1400854830345017 1.0 0.4134157567260242 9 P29375,Q8NB78,Q7LBC6,Q9UPP1 4 +Met activates rap1 and rac1 0.5947363692995749 1.473032367658922 0.1407423082693704 1.0 0.414285155651164 5 Q96N67 1 +Mitotic g1 phase and g1 s transition 0.5061357658611466 1.4721655727712215 0.1409761716712234 1.0 0.414285155651164 76 P00374,P28072,Q13616,P04183,P35244,P31751,P42771,Q15008,Q9UBD5,O00487,P33992,P49721,P60900,P25787,P20618,Q13309,P20248,Q00534,P63151,Q99741,Q07864,P25786,P14635,P33991,P09884,O43242,P11802,Q13200,P33993,P25789,P28066,O75832,O43913,P49720,P61289,P04818 36 +Coenzyme a biosynthesis 0.5835820895522457 1.462830501200173 0.1435137647766531 1.0 0.416028424574463 3 Q13057,Q9NVE7 2 +Synthesis of pips at the plasma membrane 0.6207064381330581 1.4609132614923432 0.1440392467580353 1.0 0.416028424574463 13 Q96T51,O15357,O00443,Q13614,Q01968,Q8TBX8,Q12923,Q8NCE2 8 +Processive synthesis on the lagging strand 0.6176862907750048 1.4605728840763854 0.1441326922730552 1.0 0.416028424574463 12 P35244,P28340,P49005 3 +Hdr through homologous recombination hrr 0.6439459430978226 1.4597859691923576 0.14434890586868 1.0 0.416028424574463 25 Q07864,Q92547,P35244,P35251,Q13535,P28340,Q13315,P49005 8 +Irf3 mediated activation of type 1 ifn 0.5771411518949487 1.4545107558500023 0.1458047536480671 1.0 0.41787341767178 2 Q9UHD2 1 +Downregulation of tgf beta receptor signaling 0.5944441118904346 1.4490838680601372 0.1473141625337621 1.0 0.4204654741723396 6 O14980,P62136 2 +Inactivation of csf3 g csf signaling 0.5893299290828244 1.4451488970149888 0.148416066943577 1.0 0.4226747688612145 5 P40763,Q15369 2 +Inositol phosphate metabolism 0.6002989536621894 1.4398398787292137 0.1499127057903444 1.0 0.4226747688612145 8 Q96PE3,O15357,Q9BW91,Q13572,Q01968,P19174,Q9NPH2 7 +Dscam interactions 0.5808841964053881 1.4248138140391238 0.1542110280807778 1.0 0.4304283715507653 4 Q16512,Q13153 2 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.6312773072986366 1.420690971536223 0.1554066183834177 1.0 0.4328961914888791 21 P27695,Q07864,P09874,P35244,P35251,P28340,P49005 7 +Recognition of dna damage by pcna containing replication complex 0.6243140920977193 1.4140180555222177 0.1573566011961698 1.0 0.4360686012810313 18 P35251,P35244,Q07864,P28340 4 +Processive synthesis on the c strand of the telomere 0.6069688044871767 1.4046605574328035 0.160122239782555 1.0 0.4391653762600968 12 P35244,P18858,P54132,P28340,P49005 5 +Signaling by fgfr4 0.5896133597265975 1.4039361271827322 0.1603378704854057 1.0 0.4391653762600968 7 Q06124,P28482 2 +Signaling by fgfr3 0.5896133597265975 1.4039361271827322 0.1603378704854057 1.0 0.4391653762600968 7 Q06124,P28482 2 +Signaling by fgfr1 0.5896133597265975 1.4039361271827322 0.1603378704854057 1.0 0.4391653762600968 7 Q06124,P28482 2 +Regulation of tp53 expression and degradation 0.6064097593070108 1.401742828000667 0.1609920564800278 1.0 0.4396443192676594 12 O96017,P42345,P31751,P42771,Q13315,Q9UER7 6 +Interleukin 1 processing 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.4413428052901297 2 Q00653 1 +Cytosolic iron sulfur cluster assembly 0.5909776407419564 1.3915546659871594 0.1640572949079248 1.0 0.4453899217226866 8 P18074,P28340,O76071 3 +Activation of rac1 downstream of nmdars 0.5674626865671715 1.379659802522902 0.167691415056975 1.0 0.4494735040495171 3 Q14012,Q14155 2 +Sema4d mediated inhibition of cell attachment and migration 0.5674626865671712 1.3796598025229008 0.1676914150569755 1.0 0.4494735040495171 3 Q9NWH9,P61586 2 +Carboxyterminal post translational modifications of tubulin 0.5827150964930564 1.3682334288841198 0.1712390209716106 1.0 0.4539598080306799 7 P04350,Q13885,Q9BUF5 3 +Resolution of abasic sites ap sites 0.6258134034745443 1.3675287256539492 0.1714596397238179 1.0 0.4539598080306799 24 P27695,Q07864,P29372,P09874,P35244,P35251,P28340,P49005 8 +Formation of incision complex in gg ner 0.6073715559501631 1.3622030262470324 0.1731338210484831 1.0 0.4557879001086962 15 O75925,Q86WJ1,P18074,P35244 4 +Gap junction assembly 0.5769391006226542 1.3586243952230608 0.1742656407591181 1.0 0.4570363031229701 6 P04350,Q9BUF5 2 +Transport of connexons to the plasma membrane 0.5769391006226542 1.3586243952230608 0.1742656407591181 1.0 0.4570363031229701 6 P04350,Q9BUF5 2 +Post chaperonin tubulin folding pathway 0.5941712481465369 1.3543171924170505 0.1756352034456045 1.0 0.4597607020515825 11 P04350,Q99426,Q9BTW9,Q9BUF5 4 +Netrin 1 signaling 0.5960399400031187 1.3476111012744407 0.1777834981562169 1.0 0.4643480123628411 12 Q06124,Q16512,Q00169,Q14185,P60953,Q13153,P19174,O00401 8 +Formation of xylulose 5 phosphate 0.5608955223880672 1.345729366758361 0.1783898119437101 1.0 0.4643480123628411 3 P14550,Q00796 2 +Mitotic metaphase and anaphase 0.2619029053911055 1.337254817176997 0.1811394740365175 1.0 0.4689367874022788 141 P28072,Q92973,Q6P1K2,Q15008,Q2NKX8,Q9P258,Q99661,P49721,O14980,Q9BUF5,P50748,P25787,P20618,Q14997,Q14204,Q92674,P63151,P04350,Q9UJX5,Q29RF7,Q8WUX9,Q8IXJ6,P14635,O43237,Q5SRE5,O43242,Q13200,P28066,O75832,P63167,O95067,Q14008,Q9NTI5,Q14674,P49720,P61289,Q99986,Q9H900,Q7Z460,Q7Z5K2,P53350,Q14738 42 +Translesion synthesis by polk 0.5875694854772221 1.33717724513443 0.1811647876510962 1.0 0.4689367874022788 10 P35244 1 +Dap12 signaling 0.5581897282322542 1.3317446680429346 0.1829441057653005 1.0 0.4717853562407564 3 P19174 1 +Hdr through single strand annealing ssa 0.6005991159862641 1.3003363149777305 0.1934857267193384 1.0 0.4906570360231232 17 Q92547,Q13535,P35244,Q13315 4 +Homologous dna pairing and strand exchange 0.6005991159862641 1.3003363149777305 0.1934857267193384 1.0 0.4906570360231232 17 Q92547,Q13535,P35244,Q13315 4 +Caspase activation via extrinsic apoptotic signalling pathway 0.5648568246031209 1.2961298106886796 0.1949307661048578 1.0 0.4906570360231232 6 P42574,P49327 2 +Diseases of immune system 0.5597925731370419 1.2925216553818508 0.1961765514227265 1.0 0.4906570360231232 5 P09429,O15111 2 +Constitutive signaling by aberrant pi3k in cancer 0.5641214709049619 1.2923262114284375 0.1962441983878127 1.0 0.4906570360231232 6 Q06124,Q9NWH9,O43815,P84095 4 +Gap filling dna repair synthesis and ligation in gg ner 0.6013349286958545 1.2921818664650662 0.1962941699661757 1.0 0.4906570360231232 18 Q07864,P35244,P35251,P28340,P49005 5 +Negative feedback regulation of mapk pathway 0.5551378121471433 1.2917904938131564 0.1964297083244059 1.0 0.4906570360231232 4 P28482 1 +Regulation of signaling by cbl 0.5550339275013745 1.291253453805931 0.1966158050826472 1.0 0.4906570360231232 4 P22681 1 +The phototransduction cascade 0.5536158004808003 1.283922410340213 0.1991691050832771 1.0 0.4943661715459914 4 P50579 1 +Map3k8 tpl2 dependent mapk1 3 activation 0.5605494840789523 1.2738515637271626 0.2027160269455585 1.0 0.500488947521006 6 O15111 1 +Visual phototransduction 0.5639438415098108 1.2710418667691763 0.2037137546938683 1.0 0.50206049472425 7 P29375,P50579 2 +Membrane trafficking 0.2303164547783637 1.2561133144560228 0.2090748894751986 1.0 0.5107453363278138 240 Q9UM54,O14579,Q9UIQ6,Q9UNS2,Q15436,Q99816,P84085,Q92905,P31751,Q01968,P18085,P53618,O95782,Q13190,O60343,O00139,Q99661,Q14203,Q9UBF2,Q14746,P20645,Q9BUF5,P24386,P61160,Q13885,Q9Y496,Q14204,Q9Y296,Q10567,Q9Y678,Q9Y6B6,Q9BXS5,Q9NZ32,P04350,Q96KP1,Q8TC07,O15084,P53621,Q9UBC2,O00203,P50570,Q9NRW7,O94973,O00443,P49407,Q8WUX9,Q00610,Q96Q89,O95248,O43237,P47755,O14976,O95486,O60333,P43034,P63167,P53992,Q7Z392,Q9BW19,P22681,Q5VZE5,Q96JB2,P35579,Q8NC96,O15027,Q15042,Q15102,Q8TAG9,Q5VIR6,Q92538,Q86X10,Q9UID3,Q9Y5X3,O00401,O00743 75 +E2f mediated regulation of dna replication 0.5748938423792299 1.253913924430368 0.2098732932960358 1.0 0.5117962766341928 11 Q9UBD5,P14635 2 +Termination of translesion dna synthesis 0.5925579292246417 1.2457134662015457 0.2128696080551662 1.0 0.5181939670694938 18 P35251,P35244,Q07864,P28340 4 +Vitamin b5 pantothenate metabolism 0.5530302031723021 1.2349745671642418 0.2168399696332483 1.0 0.5250028153769847 6 P49327,Q9NRN7,Q13057,Q9NVE7 4 +Map2k and mapk activation 0.5708849213404331 1.2330553254890275 0.2175551234943475 1.0 0.5250028153769847 11 P46940,P49407,P28482 3 +Purine ribonucleoside monophosphate biosynthesis 0.5645013158654049 1.2172876859543065 0.2234947778204041 1.0 0.5362029256127251 10 P31939,Q06203,P49915,P12268,P22102,P20839,O15067 7 +Signaling by receptor tyrosine kinases 0.2579525734200961 1.216644903492518 0.2237393502556695 1.0 0.5362029256127251 118 P36507,Q14185,O75116,P46109,P31751,Q00535,Q9Y2A7,Q7L576,Q9Y5K8,P17612,P51452,O60610,O75348,Q14839,P40763,Q96F07,Q8WUW1,O14654,Q06124,Q9UBC2,P42345,Q96P70,P50570,O94973,Q15418,Q00610,Q96N67,Q9UQB8,Q14155,Q16512,Q13464,P28482,P22681,P60953,P40818,Q15334,Q99570,Q14738 38 +Dual incision in gg ner 0.5971483307850568 1.2124641030754442 0.2253347756222905 1.0 0.5387610864197326 24 Q07864,P35244,P35251,P28340,Q86WJ1,P18074,P49005 7 +Activation of the pre replicative complex 0.5885277581619718 1.2021028209084368 0.2293236935801841 1.0 0.5458218049254382 20 O43913,Q07864,P25205,P35244,P09884,P33991,Q9UBD5,P33993,P49642,Q99741,P33992 11 +Signaling by interleukins 0.2559543730964084 1.1884018764370965 0.2346751175135595 1.0 0.5538173401423561 114 P28072,Q13616,O15357,O00170,P51532,Q15008,Q12923,Q13126,P49721,P17612,P25787,P20618,P14174,P51452,Q14997,P40763,Q06124,Q00169,P42574,Q15418,O43242,Q13501,Q13200,P28066,O75832,O15111,P09429,P28482,P22681,P60953,P49720,P61289,Q14738 33 +Regulation of ifng signaling 0.5340418669870165 1.182803085558691 0.2368871974387696 1.0 0.5580901770167623 4 O75925 1 +Intraflagellar transport 0.5696923163620347 1.178997636527468 0.2383991169593904 1.0 0.5607018148452668 14 P04350,P63167,Q9BUF5,Q13885,Q8NCM8,Q92973,Q9Y496,Q96EX3,Q9BW83,Q96FJ2 10 +Sema4d induced cell migration and growth cone collapse 0.5497274679025792 1.177842210615015 0.2388595172100072 1.0 0.5608356907464697 8 P35580,Q13464,P35579,O75116,P61586 5 +Pi3k akt signaling in cancer 0.5619595587144112 1.1699557511508658 0.2420187762383738 1.0 0.5653884016325037 12 Q06124,O15111,P31751,P42345 4 +Signal transduction by l1 0.5566091635453594 1.1589022847895607 0.246496017499386 1.0 0.5748816515505814 11 Q16512,P36507,P28482,P19784,P67870 5 +Receptor mediated mitophagy 0.5269704185818055 1.146338820071273 0.2516549863037349 1.0 0.5849505534484809 4 P67870,P19784 2 +Diseases of dna repair 0.5429160378589709 1.1055313241222822 0.2689294291118398 1.0 0.6009837724525038 10 Q13315,P20585 2 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.5390029294025879 1.1035519182290503 0.269787558260915 1.0 0.6019337174681731 9 Q93008,O75909,P28482 3 +Signaling by wnt 0.3458208499006069 1.0998895385234608 0.2713802533630631 1.0 0.6038651452663152 93 Q70CQ2,P49841,P68400,P28072,Q13616,Q08209,P31751,P51532,Q15008,P07737,O95782,O00487,Q9Y4A5,P49721,O14980,P98170,P25787,P20618,Q14997,O75436,P61586,P67870,Q9HCE1,Q96QK1,O94973,Q00610,P19784,O43242,Q13200,P28066,Q9HCK8,O75832,P25789,P40818,P49720,P61289,Q14738,Q13618 38 +Trna modification in the nucleus and cytosol 0.5655072914578468 1.0802815880963552 0.2800168060945194 1.0 0.6168357535204151 20 P57081,Q2VPK5,Q96FX7,P07814,Q8TEA1,Q9UJA5,O60294,Q7Z4G4,Q9UBP6 9 +Pecam1 interactions 0.5087427531645555 1.0765953826088643 0.2816610679478053 1.0 0.6175218997593839 3 Q06124 1 +Nuclear events kinase and transcription factor activation 0.5453755193364191 1.0679314514461753 0.285551434032655 1.0 0.6250653437880166 13 P28482,P50570,P51452,Q15418,Q14839,Q00535 6 +Rna polymerase ii transcription 0.2084924789628897 1.0653519018366775 0.2867167138748883 1.0 0.6266292960473188 334 Q15648,P35244,P10589,P51532,O75909,Q00535,Q13535,Q8IYB3,Q12873,Q9H3P2,Q9NVI1,P49721,Q9ULK4,Q14241,P42858,Q68E01,Q14997,P20248,Q9NYV4,Q00534,Q08945,Q99873,O60942,Q96P16,O43242,P28066,O75832,P49720,Q9Y3Y2,O75880,P49841,P68400,Q92547,P42771,Q15369,Q92600,P17612,P18615,P25787,P20618,P46087,Q92620,Q9HCE1,P55212,Q9UJX5,Q16881,P19784,P14635,O60244,Q13315,P11802,O14744,Q13200,O96017,Q9NV88,Q9Y2X0,Q9Y5B9,P28072,Q93008,A5YKK6,Q13526,P54132,Q8TBX8,Q9HCL2,Q92759,P25440,Q14839,Q13309,P67870,P18074,P30307,Q6P9B9,O60921,O75182,P28482,Q9UIV1,Q13616,P09874,P31751,P49327,Q15008,Q9UER7,O14965,Q14353,Q06124,P42345,Q13555,P51003,P61289,Q8IWI9 90 +Dex h box helicases activate type i ifn and inflammatory cytokines production 0.5098263453413066 1.058220385993424 0.2899549792946221 1.0 0.6327118072520012 4 Q00653 1 +Biosynthesis of specialized proresolving mediators spms 0.4950760966875429 1.03114869998952 0.3024710931719161 1.0 0.6488191659088941 2 Q14914 1 +Synthesis of leukotrienes lt and eoxins ex 0.4950760966875429 1.03114869998952 0.3024710931719161 1.0 0.6488191659088941 2 Q14914 1 +Rsk activation 0.5022110449530377 1.0192607647084513 0.3080791855390425 1.0 0.6538547823559513 4 P28482 1 +Ctla4 inhibitory signaling 0.5101640638660365 1.014519058906507 0.3103351398421043 1.0 0.6565690173219559 6 Q06124,P31751 2 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5128589623996507 1.0079888576576168 0.3134598113664026 1.0 0.6611671286787553 7 O15111,P09429,Q00653 3 +Mrna decay by 5 to 3 exoribonuclease 0.5164818529041931 1.0069127643053537 0.313976697484293 1.0 0.6612539537926777 8 Q8IZH2,P26196,Q86TB9 3 +Activation of atr in response to replication stress 0.5551811256272923 1.005757875279054 0.3145320553990487 1.0 0.6614214175562446 22 P30307,O43913,P35244,Q13535,Q9UBD5 5 +Cytosolic trna aminoacylation 0.5541369175841239 0.9911288994457726 0.3216226431004756 1.0 0.6742918158516759 23 P47897,P49589,P26639,P07814,P41252,O43776,P23381,P54136,Q9NSD9,Q9P2J5,P26640 11 +Gastrin creb signalling pathway via pkc and mapk 0.5004031802718951 0.9870658297673192 0.3236103677661068 1.0 0.6758114189880847 5 P28482 1 +Irak1 recruits ikk complex 0.4911608580425158 0.9866667267424218 0.3238060467957298 1.0 0.6758114189880847 3 O15111 1 +P75ntr negatively regulates cell cycle via sc1 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.6760758500199886 2 Q13547 1 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.4931568289401922 0.973134871684364 0.3304862746398425 1.0 0.6856357041035538 4 P17612 1 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.5467929092243048 0.9717145100747904 0.331192596146622 1.0 0.6860770620623019 21 P35251,Q07864,P35244,P28340 4 +Heme signaling 0.4999246893012409 0.9624332821921135 0.3358320019924894 1.0 0.6946525041213695 6 O14980 1 +Sema4d in semaphorin signaling 0.5145644703208024 0.9601997551616726 0.336954690061146 1.0 0.6959391072585333 10 P35580,Q13464,P35579,O75116,P61586 5 +Pi metabolism 0.5480389045060517 0.959122032017148 0.3374972724937708 1.0 0.6960255322942751 23 Q9NZC3,O15357,O00443,Q13614,P42356,Q01968,Q08AM6,O95248,Q12923,Q99570,Q8NCE2 11 +Telomere c strand synthesis initiation 0.4911973779946625 0.94036881223632 0.347028413967156 1.0 0.71176929747322 5 P09884,P49642,Q15554 3 +Chrebp activates metabolic gene expression 0.4886858481850423 0.927680151588184 0.3535735072855053 1.0 0.7221497027247695 5 P49327,P53396 2 +Parasite infection 0.5435808055280793 0.9272410359422738 0.3538014011191137 1.0 0.7221497027247695 24 P28482,Q14185,P35579,P60953,Q9NZQ3,Q9Y2A7,Q96F07,Q9UQB8,O00401,Q8WUW1 10 +Cd28 co stimulation 0.5028927587743826 0.9191353894896978 0.3580247606835187 1.0 0.7277768185265647 9 Q16512,P31751,P42345 3 +G2 m checkpoints 0.367278960514509 0.9169359862190464 0.3591761852584341 1.0 0.7277768185265647 88 P28072,Q92547,P35244,P54132,Q15008,Q13535,Q9UBD5,O00487,P33992,P49721,P60900,P25787,P20618,Q14997,Q99741,P30307,Q14676,P25786,P14635,Q13315,O43242,Q13200,P33993,P28066,O75832,O96017,P25789,O60921,O95067,O43913,P49720,P61289,Q99640 33 +Erks are inactivated 0.4937746523436752 0.9112391589833804 0.3621693754560664 1.0 0.7327735544162043 7 P51452,P28482 2 +Mastl facilitates mitotic progression 0.4851238980525999 0.9097261983739392 0.3629669242015607 1.0 0.7332012656402891 5 P14635 1 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.4878322465129864 0.9013849741408544 0.3673836677104694 1.0 0.7390206919212047 6 O15111,Q14258 2 +Dna replication 0.3656215671000193 0.8996992273515463 0.3682803346877801 1.0 0.7394700445351422 88 P28072,Q13616,P25205,P35244,Q15008,P49643,P28340,Q9UBD5,O00487,P33992,P49721,P60900,P25787,P20618,P20248,Q14997,Q13309,P18858,Q99741,P62195,Q07864,P55036,Q9UJX5,P25786,P09884,P33991,O43242,Q13200,P33993,P49642,P28066,O75832,P49005,P25789,O43913,P49720,P61289,P35251 38 +Rho gtpases activate wasps and waves 0.5284671846638614 0.8989655014090022 0.3686710365919809 1.0 0.7394700445351422 19 P28482,Q9UQB8,P60953,Q9NZQ3,Q9Y2A7,Q96F07,Q7L576,O00401,Q8WUW1 9 +Pyroptosis 0.4816119757580723 0.8920751514651633 0.3723526526496699 1.0 0.7457783676989065 5 P42574,Q8WUX9 2 +Translesion synthesis by polh 0.509227530930531 0.8831736499166056 0.3771424561347354 1.0 0.7523391134166585 13 P35244 1 +Synthesis of dna 0.4030002360990441 0.8810861889874583 0.3782711718719618 1.0 0.7532907290859985 82 P28072,Q13616,P25205,P35244,Q15008,P49643,P28340,Q9UBD5,O00487,P33992,P49721,P60900,P25787,P20618,P20248,Q14997,Q13309,P18858,Q99741,P62195,Q07864,P55036,Q9UJX5,P25786,P09884,P33991,O43242,Q13200,P33993,P49642,P28066,O75832,P49005,P25789,O43913,P49720,P61289,P35251 38 +Ephb mediated forward signaling 0.516782724081451 0.8774567746988289 0.3802385871422014 1.0 0.7545661081010352 16 Q16512,Q13464,P61160,P60953,O75116,P61586,O00401 7 +Negative regulation of the pi3k akt network 0.5072208734031871 0.8730745037430506 0.3826224698867539 1.0 0.7565366047547482 13 Q06124,Q14738,P28482,P31751 4 +Ikba variant leads to eda id 0.4715619622648452 0.8642594182317473 0.3874453979453593 1.0 0.7638994370837583 4 O15111 1 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.4934858936449894 0.85397471858745 0.3931189974170794 1.0 0.7728930783730417 10 Q93008,P49427 2 +Regulation of tnfr1 signaling 0.4927459837406522 0.8502839744485241 0.3951672240910466 1.0 0.7739343659057834 10 Q96EP0,P98170,Q6GQQ9,Q96BN8,Q14790,O15111 6 +Translation of replicase and assembly of the replication transcription complex 0.4640711831532479 0.8500109603384263 0.3953189926569109 1.0 0.7739343659057834 3 Q8WUX9 1 +Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.4680628916672903 0.8468058669156813 0.3971033375626318 1.0 0.7754034288879524 4 Q8TEW0 1 +Constitutive signaling by egfrviii 0.4721226188146458 0.8446599008539466 0.398300754119423 1.0 0.7754034288879524 5 P22681 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.4721226188146458 0.8446599008539466 0.398300754119423 1.0 0.7754034288879524 5 P22681 1 +Signaling by egfr in cancer 0.4721226188146458 0.8446599008539466 0.398300754119423 1.0 0.7754034288879524 5 P22681 1 +Microrna mirna biogenesis 0.4902517204241217 0.8207380254220267 0.4117955063349026 1.0 0.792791902777721 11 Q9HAV4 1 +Tp53 regulates transcription of cell death genes 0.4737476676292325 0.8113618729447537 0.4171578876901149 1.0 0.8008970495708008 7 Q13315,P55212 2 +Base excision repair 0.5259592595372498 0.8075184771937707 0.4193678335614093 1.0 0.8040293636556675 28 P27695,Q07864,P29372,P09874,P35244,P35251,P28340,P49005 8 +Innate immune system 0.2073568515445379 0.7992753168871816 0.4241307880148093 1.0 0.8120410404140288 292 Q14185,Q9UII4,P49721,Q9Y5K8,P53396,Q14997,P31949,Q96RD7,Q8WUW1,O14802,P47755,O43242,P11216,P28066,O75832,Q13464,P60953,Q9NW08,P49720,P46940,O75165,P13639,P17612,P25787,P20618,Q14204,P35573,P78527,Q9BXS5,Q9NZ32,Q5T4S7,Q7Z6Z7,O94973,Q15418,Q9UDY8,Q13200,P63167,Q14738,O00401,P07741,P28072,Q08209,Q13526,P61081,P53618,Q9Y2A7,Q7L576,P49427,O60610,O75348,P61586,P63172,P67870,O00764,Q9UNP9,Q9NZQ3,P46976,Q9UQB8,P06744,P17858,P18669,P25789,O15111,P09429,P28482,Q00653,Q14790,Q13616,Q9UQ80,O95352,P19174,Q15008,Q9BUI4,O00487,P20839,Q86VP6,P06737,P61160,P14174,P51452,P60900,Q8TBC4,Q96F07,Q14004,Q06124,Q13404,P50570,P07437,P09972,Q14258,Q16512,P22392,P35579,P42785,P61289,Q99570,Q5T9A4 97 +Recycling of eif2 gdp 0.4708318446781718 0.7969987359787974 0.4254517654296021 1.0 0.8134497303261995 7 Q13144 1 +Crmps in sema3a signaling 0.4704429111434349 0.795086743297369 0.4265630454881692 1.0 0.8144541665227407 7 Q00535,Q9BPU6 2 +Triglyceride metabolism 0.4679529001712798 0.7828680809411804 0.4337045830988879 1.0 0.8248664363245716 7 Q9HCL2,P17612 2 +Dna damage bypass 0.5143438478082089 0.77696802756405 0.4371776338661197 1.0 0.8290271638116049 24 P35251,Q07864,P35244,P28340 4 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4767012469017111 0.7710272553233094 0.4406907766436543 1.0 0.8328817771211012 10 O14965,P30307,P14635 3 +Assembly of the orc complex at the origin of replication 0.4730005402496058 0.7704923267062223 0.4410079050080076 1.0 0.8328817771211012 9 Q9UBD5 1 +Cell death signalling via nrage nrif and nade 0.4816413500283295 0.7619908916554834 0.4460654403644926 1.0 0.8369416971082912 12 Q9H8V3,P42574,Q92974,Q13501,Q9Y5V3 5 +Lagging strand synthesis 0.4988427158668053 0.7618884403640077 0.4461265897675637 1.0 0.8369416971082912 18 P35251,P35244,P28340,P49005 4 +Ikk complex recruitment mediated by rip1 0.4551596484445019 0.761103437977847 0.4465952871692975 1.0 0.8369416971082912 5 Q6SZW1,O15111,Q13404 3 +Platelet sensitization by ldl 0.4551130782652533 0.7608764782159746 0.4467308490919377 1.0 0.8369416971082912 5 Q06124,Q14738 2 +Nrage signals death through jnk 0.4670854132354411 0.7598028612973042 0.4473724323391801 1.0 0.8369416971082912 8 Q9H8V3,Q92974,Q9Y5V3 3 +Retrograde transport at the trans golgi network 0.4895769315211907 0.7557869612730143 0.4497769354733807 1.0 0.8391811279302003 15 Q5VZE5,Q96JB2,Q14746,Q9UID3 4 +Traf6 mediated nf kb activation 0.4620171210135759 0.7352160008772929 0.4622079556680138 1.0 0.8555945989084528 8 P09429,O15111 2 +Condensation of prophase chromosomes 0.4753113031329504 0.7312115866355294 0.4646499240250983 1.0 0.8577560029236881 12 P14635,Q9UPP1,Q9NTJ3,P42695 4 +Tnf signaling 0.4710833516356956 0.7269014396537765 0.4672863352057805 1.0 0.8599158453145078 11 Q96EP0,P98170,Q6GQQ9,Q96BN8,Q14790,O15111 6 +Vesicle mediated transport 0.2085929464479021 0.7262341554125001 0.4676952367322071 1.0 0.8599158453145078 247 Q9UM54,O14579,Q9UIQ6,Q9UNS2,Q15436,Q99816,P84085,Q92905,P31751,Q01968,P18085,P53618,O95782,Q13190,O60343,O00139,Q99661,Q14203,Q9UBF2,Q14746,P20645,Q9BUF5,P24386,P61160,Q13885,Q9Y496,Q14204,Q9Y296,Q10567,Q9Y678,Q9Y6B6,Q9BXS5,Q9NZ32,P04350,Q96KP1,Q8TC07,O15084,P53621,Q9UBC2,O00203,P50570,Q9NRW7,O94973,O00443,P49407,Q8WUX9,Q00610,Q96Q89,O95248,O43237,P47755,O14976,O95486,O60333,P43034,P63167,P53992,Q7Z392,Q9BW19,P22681,Q5VZE5,Q96JB2,P35579,Q8NC96,O15027,Q15042,Q15102,Q8TAG9,Q5VIR6,Q92538,Q86X10,Q9UID3,Q9Y5X3,O00401,O00743 75 +Cargo trafficking to the periciliary membrane 0.4899288873392849 0.7182128563861687 0.4726260520375613 1.0 0.8666889344752114 18 Q96KP1,Q3SYG4,P49368,P18085,Q8TAG9,Q92538,O43924 7 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.4715747882461841 0.7131864045607632 0.4757304179701669 1.0 0.8672355235015378 12 O96017,P14635 2 +Mapk family signaling cascades 0.3536033401040187 0.7131107581690133 0.475777222872126 1.0 0.8672355235015378 87 P36507,P21359,Q15008,P49721,O14980,P17612,P25787,P20618,Q99956,Q14997,Q06124,Q9HCE1,Q96P70,P49407,O43924,O43242,Q13200,P28066,O75832,Q16512,Q13555,P28482,P60953,P49720,Q15334,P61289,P46940,Q14738,Q13618 29 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.4990550516151697 0.7126801986270584 0.4760436722530023 1.0 0.8672355235015378 52 P08708,P46782,P62847,P62861,P62701,P62241,P15880,P62081,P62269,P62841,P62280,P61247,P62854,P60866,P62851,P62753,Q14240,Q04637,P62266,Q14152 20 +Establishment of sister chromatid cohesion 0.4557706756726708 0.7051760151762901 0.4807007055241961 1.0 0.8712788525284816 8 Q7Z5K2,Q9NTI5 2 +Rhobtb3 atpase cycle 0.4325015160626697 0.6954979691367477 0.4867432834695104 1.0 0.8712788525284816 3 Q13618 1 +Costimulation by the cd28 family 0.4741631696279544 0.6953978329802385 0.4868060182232745 1.0 0.8712788525284816 14 Q06124,Q16512,P42345,P60953,P31751 5 +Intracellular signaling by second messengers 0.3319832078331668 0.6950266341468886 0.4870386103702375 1.0 0.8712788525284816 90 P49841,P68400,P28072,Q13330,P31751,P19174,Q8TBX8,Q12873,Q15008,O00487,P49721,P98170,P17612,P60900,P25787,P20618,Q14839,O94776,Q14997,P67870,Q96B36,Q06124,Q9HCE1,P42345,P19784,O43242,Q13200,P28066,O75832,P25789,O15111,Q15382,Q13555,P28482,P49720,P61289,Q14738 37 +Signaling by moderate kinase activity braf mutants 0.4689159019953253 0.6850760630617921 0.4932959242442214 1.0 0.8813384764774649 13 P46940,P49407,Q13555,P28482 4 +Meiotic recombination 0.4610921356081045 0.6632387209473114 0.5071776760664521 1.0 0.9026593722565536 12 P35244 1 +Insulin processing 0.44595815019302 0.6586291309119164 0.5101339517029151 1.0 0.9067598374258976 8 Q8TAG9 1 +Phenylalanine and tyrosine metabolism 0.43219696751232 0.65116102470578 0.5149425469150724 1.0 0.9108233845965646 5 P61457 1 +Ticam1 rip1 mediated ikk complex recruitment 0.4267037666147993 0.6462738972531573 0.5181019894428567 1.0 0.9150721287491368 4 O15111,Q13404 2 +Rho gtpases activate rocks 0.4599366096623971 0.6426603859599331 0.5204444908550347 1.0 0.9180429470666222 13 Q16512,P60660,P35580,Q13464,P35579,O75116,P61586 7 +Nuclear events stimulated by alk signaling in cancer 0.4558699386273878 0.6387269064529335 0.5230006057793655 1.0 0.9213825627798709 12 P28482,P62753,Q13616,Q00610 4 +Transcriptional regulation of white adipocyte differentiation 0.4575389204736699 0.6314646730401577 0.5277367408600231 1.0 0.9253549043907862 13 Q15648,Q9ULK4,Q96EK7,O60244,Q9Y2X0 5 +Negative regulators of ddx58 ifih1 signaling 0.4427083009675583 0.6260466008712704 0.5312843757243058 1.0 0.927745329468323 9 Q9UII4,Q14258 2 +Neddylation 0.4123390611702263 0.6117365606802408 0.5407120684313578 1.0 0.9394872188994842 74 P28072,Q9UNS2,Q13616,Q92905,P61081,Q15008,Q15369,O00487,Q86VP6,P49721,Q14999,P60900,P25787,P20618,Q13309,Q14997,Q5TAQ9,Q8TBC4,Q13564,Q9BW61,Q9Y3I1,P62195,P61962,P25786,O43242,Q13200,P25789,P28066,O75832,O60826,Q7L5N1,P49720,P61289,Q15370,Q13620,Q13618 36 +Transcriptional regulation by mecp2 0.4535670800005721 0.5987467629271414 0.5493417682301476 1.0 0.9509153895889229 14 Q9HCE1,Q13555,P42858,Q14353 4 +Growth hormone receptor signaling 0.4184633192061478 0.5876264301100633 0.5567830666814657 1.0 0.96020901077821 5 P28482 1 +Sumoylation of transcription factors 0.4213290113170548 0.5810363423861797 0.5612159601822022 1.0 0.9645685404449754 6 P42771 1 +Prolonged erk activation events 0.4245660415557666 0.5776883116784646 0.5634745718282879 1.0 0.9645685404449754 7 P36507,P28482 2 +Intra golgi and retrograde golgi to er traffic 0.3065583337465045 0.5749053307413671 0.5653553244952894 1.0 0.9665976642662388 92 O14579,P84085,P18085,P53618,Q13190,Q99661,Q14203,Q9UBF2,Q14746,P20645,Q9BUF5,Q13885,Q9Y496,Q14204,Q9Y678,Q9NZ32,P04350,P53621,Q9NRW7,Q96Q89,O43237,P47755,O60333,P43034,P63167,Q9BW19,Q5VZE5,Q96JB2,Q15042,Q15102,Q5VIR6,Q92538,Q9UID3 33 +Rho gtpases activate nadph oxidases 0.4229563141941073 0.5704200428889385 0.5683928386910833 1.0 0.9681054993904936 7 Q99570,P28482 2 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.4146449794943031 0.570310249804487 0.5684672901973529 1.0 0.9681054993904936 5 P09884,P49642 2 +Negative regulation of mapk pathway 0.4374241688798469 0.5694907292057484 0.5690231604331175 1.0 0.9681054993904936 11 P36507,P28482,Q99956 3 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.3998806326469688 0.5653017913937095 0.5718685104529164 1.0 0.9686682119591375 2 P49916 1 +Rho gtpases activate iqgaps 0.4383809543646045 0.5586874414112618 0.576375051711498 1.0 0.9734645466330284 12 P04350,P60953,Q9BUF5,P46940 4 +Fceri mediated mapk activation 0.4264751672563877 0.5522114113862657 0.5808035169579802 1.0 0.9784650284460576 9 Q16512,P19174,P28482 3 +Signaling by tgf beta receptor complex 0.4614844034386377 0.5512715128296053 0.5814475636665062 1.0 0.9784650284460576 21 O14980,P28482,P22681,P09874,Q93008,P62136,Q8TEW0,P61081,O75909,P62942 10 +Tcf dependent signaling in response to wnt 0.4389920002976121 0.5364813076204732 0.5916259512257018 1.0 0.9875481033592344 64 Q70CQ2,P49841,P68400,P31751,P51532,Q15008,Q9Y4A5,P49721,O14980,P25787,P20618,Q14997,P67870,P19784,O43242,Q13200,P28066,Q9HCK8,O75832,P40818,P49720,P61289,Q14738,Q13618 24 +Metabolism of nitric oxide nos3 activation and regulation 0.4152866136480342 0.536202804099036 0.5918183957541312 1.0 0.9875481033592344 7 P50570,Q9Y314 2 +Tp53 regulates transcription of dna repair genes 0.4750020521459225 0.5268104612212495 0.5983252175240961 1.0 0.9942841970547974 35 Q9H3P2,Q08945,Q14676,P18615,P30876,Q14241,Q9Y5B9,Q8IXH7,O75909,Q13535,Q9NYV4,Q13315,Q15369,Q15370,Q14004,Q92759,P18074,Q9NVI1 18 +Cd28 dependent vav1 pathway 0.4088276424365758 0.5252478159941644 0.5994109287609541 1.0 0.9942841970547974 6 Q16512,P60953 2 +Mapk targets nuclear events mediated by map kinases 0.4237403522309568 0.524189015638844 0.6001470800927877 1.0 0.9942841970547974 10 P28482,P51452,Q15418,Q14738,Q16539 5 +Erk mapk targets 0.4237403522309568 0.524189015638844 0.6001470800927877 1.0 0.9942841970547974 10 P28482,P51452,Q15418,Q14738,Q16539 5 +Cd209 dc sign signaling 0.402629258891663 0.5169255176844663 0.605208153696998 1.0 0.9969232296923604 5 Q16512,P17612 2 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.3974760762378642 0.5136772212995846 0.6074776802513879 1.0 0.9969232296923604 4 Q9Y478 1 +Orc1 removal from chromatin 0.4637307531821546 0.5092227912013197 0.6105960695282275 1.0 0.9992619473567826 51 P28072,Q13616,P25205,Q15008,Q9UBD5,O00487,P33992,P49721,P60900,P25787,P20618,Q13309,Q14997,P20248,Q99741,P62195,P55036,P25786,P33991,O43242,Q13200,P33993,P28066,P25789,O75832,O43913,P49720,P61289 28 +Oas antiviral response 0.3911666374126441 0.505930943209517 0.6129051289867933 1.0 0.9992619473567826 3 P61221 1 +Unblocking of nmda receptors glutamate binding and activation 0.3954092150286474 0.5046803010020257 0.6137833990868018 1.0 0.9992619473567826 4 Q15334 1 +Ras activation upon ca2 influx through nmda receptor 0.3954092150286474 0.5046803010020257 0.6137833990868018 1.0 0.9992619473567826 4 Q15334 1 +Long term potentiation 0.3954092150286474 0.5046803010020257 0.6137833990868018 1.0 0.9992619473567826 4 Q15334 1 +Polymerase switching 0.4288213857997024 0.5023525945667149 0.6154195189352336 1.0 0.9992619473567826 13 P35251,P28340 2 +Molybdenum cofactor biosynthesis 0.3947446999104201 0.5017996395013967 0.6158084667437169 1.0 0.9992619473567826 4 Q9NQX3,O96007,Q9NZB8 3 +Cytokine signaling in immune system 0.206180803605277 0.5003756265733628 0.6168106121094385 1.0 0.9992619473567826 185 P28072,Q13616,O15357,O00170,P46109,Q13526,P31751,P51532,Q15008,Q12923,Q13126,Q15369,Q9Y3Z3,Q9UII4,P49721,P17612,P25787,P20618,P14174,P51452,Q14997,P40763,Q06124,Q00169,P42574,Q15418,O43432,Q5SRE5,O00629,Q14240,O43242,Q13501,Q13200,P28066,O75832,O15111,O75925,P09429,Q14258,Q13555,P28482,Q04637,P29372,P22681,P60953,P49720,P61289,Q14738 48 +Thrombin signalling through proteinase activated receptors pars 0.4055872480838077 0.493977294948425 0.6213222146433688 1.0 1.0 7 P49407 1 +Tnfr1 induced nfkappab signaling pathway 0.4111530613148069 0.4854060587572556 0.6273883354211054 1.0 1.0 9 Q96EP0,P98170,Q6GQQ9,O15111 4 +Deactivation of the beta catenin transactivating complex 0.4179248536677202 0.4840236396218584 0.6283690922853435 1.0 1.0 11 P31751,Q9HCK8 2 +Signaling by tgfb family members 0.4469759801071385 0.4689095336274878 0.6391343015017548 1.0 1.0 23 O14980,P28482,Q7Z3T8,P09874,Q93008,Q8TEW0,O75909,P62942 8 +Ub specific processing proteases 0.3824657809758154 0.4672412906886641 0.6403272550449253 1.0 1.0 76 Q70CQ2,Q9UPT9,P28072,Q93008,Q15008,O00487,Q9Y4A5,Q9NZL9,P49721,P60900,P25787,P20618,Q86UV5,Q13309,Q14997,P20248,P49407,P14735,P25786,Q96RU2,O43242,Q96FW1,O60493,Q13200,O94966,P25789,P28066,O75832,P40818,P49720,P61289 31 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4028116313402787 0.4658972186325138 0.6412890721245108 1.0 1.0 8 Q15334,Q15418,Q13555,P28482 4 +Nef mediated downregulation of mhc class i complex cell surface expression 0.3906081715332583 0.4653742512608816 0.6416634701215433 1.0 1.0 5 Q10567,Q9BXS5 2 +Regulation of pten stability and activity 0.4615689997158202 0.4608541335561699 0.6449032605184362 1.0 1.0 42 P28072,P68400,P31751,Q15008,O00487,P49721,P98170,P60900,P25787,P20618,Q14997,P67870,P19784,O43242,Q13200,P28066,P25789,O75832,P49720,P61289 20 +Cytosolic sulfonation of small molecules 0.3850566909044191 0.4604900492429785 0.6451645123268905 1.0 1.0 4 Q96IU4 1 +Zbp1 dai mediated induction of type i ifns 0.4010082038286133 0.4583577013437748 0.6466954754384242 1.0 1.0 8 Q00653,Q9NZI8,Q13546,Q9UHD2,O15111 5 +Rhou gtpase cycle 0.43284261686389 0.4578736668912374 0.6470432066277212 1.0 1.0 18 Q9UM54,Q16512,P60953,Q93008,Q00610,O43396,P46940 7 +Regulation of tp53 activity through methylation 0.3884522387636138 0.45634322503853 0.648143185520017 1.0 1.0 5 Q13315 1 +Programmed cell death 0.2312431770237128 0.4538970035940666 0.6499029603386599 1.0 1.0 101 P30419,P31751,P42771,P49327,Q15008,Q9Y5V3,P49721,P25787,P20618,Q14997,P40763,P55212,P42574,Q8WUX9,P16402,O00429,O43242,Q13200,P28066,O75832,P09429,Q13464,P28482,P49720,P61289 25 +Diseases of mitotic cell cycle 0.4138180387061752 0.4526123248376177 0.6508279223505973 1.0 1.0 12 Q9UJX5,Q9UER7,Q00534,Q13309 4 +Fcgamma receptor fcgr dependent phagocytosis 0.4569125348838017 0.4509115884751067 0.6520532710185354 1.0 1.0 33 Q16512,P28482,Q14185,Q9UQB8,P35579,P60953,P19174,Q9NZQ3,Q9Y2A7,Q96F07,Q7L576,O00401,Q8WUW1 13 +Interleukin 1 family signaling 0.4469089555699411 0.4398411322253567 0.6600521744681374 1.0 1.0 53 P28072,Q13616,Q15008,Q12923,O00487,P49721,P60900,P25787,P20618,Q14997,P40763,P62195,Q06124,Q13404,P55036,P25786,O43242,Q9UHD2,Q13501,Q13200,P25789,P28066,O75832,O15111,P09429,Q00653,P49720,P61289 28 +Signaling by mras complex mutants 0.3746268656716449 0.4358614559886806 0.6629372518002796 1.0 1.0 3 P62140,Q9UQ13 2 +Downregulation of erbb2 signaling 0.3900660883554614 0.4291243429486175 0.6678327378034798 1.0 1.0 7 P31751 1 +Homology directed repair 0.4540159445591842 0.4265139807327232 0.6697333628226327 1.0 1.0 42 O60921,Q07864,Q92547,P35244,P35251,Q13535,P28340,Q13315,P49005 9 +Darpp 32 events 0.3965117920984849 0.4246282392324046 0.6711077036990976 1.0 1.0 9 Q00535,Q14738,Q08209,P17612 4 +Signaling by alk 0.3801746360036343 0.4223195738444215 0.6727917728758206 1.0 1.0 5 P40763 1 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4027469931165072 0.4211641679213886 0.6736352075969607 1.0 1.0 11 Q9BQC3,Q9HA64,Q9H2P9,P63241 4 +Dna replication pre initiation 0.4254260112499669 0.4139440360835195 0.6789150927847754 1.0 1.0 61 P28072,P25205,P35244,Q15008,P49643,Q9UBD5,O00487,P33992,P49721,P60900,P25787,P20618,Q14997,Q99741,P62195,Q07864,P25786,P09884,P33991,O43242,Q13200,P33993,P49642,P25789,P28066,O75832,O43913,P49720,P61289 29 +Rhov gtpase cycle 0.4204122771763651 0.4070258670617537 0.6839889898985108 1.0 1.0 18 Q16512,P60953,Q93008,Q96KM6,Q00610,O43396,P46940,Q14155 8 +Lipophagy 0.3763440860214941 0.406939419445572 0.6840524829102415 1.0 1.0 5 P11142,Q9Y478,O60664,P54646 4 +Hiv elongation arrest and recovery 0.4289226770968548 0.4027865586751388 0.6871052501335733 1.0 1.0 22 Q9H3P2,Q08945,P18615,Q14241,Q9Y5B9,Q8IXH7,O75909,Q15370,Q15369 9 +Dectin 1 mediated noncanonical nf kb signaling 0.4470903983139074 0.3971420801642231 0.6912626906166932 1.0 1.0 43 P28072,Q13616,P61081,Q15008,O00487,P49721,P60900,P25787,P20618,Q14997,Q8TBC4,O43242,Q13200,O15111,P28066,P25789,O75832,Q00653,P49720,P61289 20 +Sulfur amino acid metabolism 0.3957247299623324 0.3933113411530834 0.6940895428085554 1.0 1.0 11 Q13126 1 +Global genome nucleotide excision repair gg ner 0.4462992936320395 0.3925777189975339 0.6946313986810397 1.0 1.0 39 O75925,Q07864,P09874,P35244,P35251,P28340,Q86WJ1,P18074,P49005 9 +Golgi cisternae pericentriolar stack reorganization 0.3952451184878683 0.3914392328155349 0.6954725974895946 1.0 1.0 11 O95067,P28482,P14635 3 +Rip mediated nfkb activation via zbp1 0.379719454183105 0.3879654752242034 0.6980415831747655 1.0 1.0 7 Q13546,Q00653,O15111,Q9NZI8 4 +Clec7a dectin 1 signaling 0.4360568228993568 0.3879294886694744 0.698068214879461 1.0 1.0 53 P28072,Q13616,Q08209,P61081,Q15008,O00487,P49721,P49427,P60900,P25787,P20618,Q14997,Q8TBC4,Q13404,O43242,Q9UDY8,Q13200,P28066,P25789,O75832,O15111,Q00653,P49720,P61289,Q14790 25 +Cohesin loading onto chromatin 0.3893278106731268 0.3820192020820581 0.7024471216894634 1.0 1.0 10 Q7Z5K2,Q9NTI5 2 +Ephrin signaling 0.3724887971831654 0.3752382392387363 0.7074832936216728 1.0 1.0 6 Q16512,Q14155 2 +C type lectin receptors clrs 0.4264850920318725 0.3751991932305245 0.7075123301534414 1.0 1.0 57 P28072,Q13616,Q08209,P61081,Q15008,O00487,P49721,P17612,P60900,P25787,P20618,P49427,Q14997,Q8TBC4,Q13404,O43242,Q9UDY8,Q13200,P25789,P28066,O75832,O15111,Q16512,Q00653,P49720,P61289,Q14790 27 +Downregulation of smad2 3 smad4 transcriptional activity 0.3675098636370719 0.3724026108509318 0.7095931103185893 1.0 1.0 5 Q93008 1 +Cdt1 association with the cdc6 orc origin complex 0.4415790943120478 0.3721756674327716 0.7097620614941458 1.0 1.0 41 P49721,O43913,P28072,P60900,P25787,P20618,P28066,P49720,P61289,Q14997,P25789,Q15008,O43242,Q9UBD5,O00487,Q13200,Q99741,O75832 18 +Regulation of tp53 activity through phosphorylation 0.4406421223802175 0.3716112819841584 0.7101822879284325 1.0 1.0 37 O60921,O96017,O14965,P68400,Q92547,Q9Y5B9,P35244,Q13526,P20248,Q00535,P19784,Q13535,Q13315,Q08945,P67870 15 +Nucleotide biosynthesis 0.3965757136749451 0.3709888604679083 0.71064582868071 1.0 1.0 13 P31939,P27708,P11172,P49915,P12268,P20839,O15067 7 +Transport and synthesis of paps 0.3533273649656836 0.3692676650895942 0.7119282245640663 1.0 1.0 2 O43252 1 +Fceri mediated nf kb activation 0.4392031261728184 0.3690720637491188 0.7120740111864701 1.0 1.0 46 P28072,Q13616,Q15008,O00487,P49721,P49427,P60900,P25787,P20618,Q14997,Q13404,O43242,Q9UDY8,Q13200,O15111,P28066,P25789,O75832,P49720,P61289 20 +Hdr through mmej alt nhej 0.3780323978173392 0.3667867793540756 0.7137780699405614 1.0 1.0 8 P39748,Q9UGN5,P09874 3 +Caspase mediated cleavage of cytoskeletal proteins 0.3794997929294247 0.3583296679663572 0.7200966183389901 1.0 1.0 9 P55212 1 +Mtorc1 mediated signalling 0.3865125441464606 0.3580566202338125 0.7203009417537187 1.0 1.0 11 Q15382,Q04637,P42345,P62753,P62942,Q96B36 6 +Hedgehog on state 0.4375531207633709 0.3558485929409422 0.7219539559015149 1.0 1.0 42 P49721,P28072,P60900,P25787,P20618,P28066,P49407,P61289,Q14997,P49720,Q9Y496,Q15008,O43242,O00487,Q13200,Q13618,P25789,O75832 18 +Activation of ampk downstream of nmdars 0.3822801696206803 0.3552702101334234 0.7223871705535558 1.0 1.0 10 P04350,Q13885,Q9BUF5 3 +Mitotic telophase cytokinesis 0.3921125601058783 0.3541760621817093 0.7232069419898293 1.0 1.0 13 Q29RF7,Q7Z5K2,Q9NTI5 3 +Regulation of ras by gaps 0.4365311317534496 0.3534362040319107 0.7237614480389372 1.0 1.0 38 P28072,P21359,Q15008,O00487,P49721,P60900,P25787,P20618,Q14997,P62195,P55036,P25786,O43242,Q13200,P28066,O75832,P25789,P49720,P61289,Q13618 20 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.3847872521084186 0.3516233944404649 0.7251207180512671 1.0 1.0 11 Q8IZH2 1 +Unwinding of dna 0.376922620301406 0.348729521104191 0.7272923792954162 1.0 1.0 9 P33993,P33991,P33992 3 +Triglyceride catabolism 0.3649164927055057 0.3466813456531705 0.728830726094085 1.0 1.0 6 P17612,P62136 2 +Interleukin 1 signaling 0.431141200956414 0.3446163245305864 0.730382831580525 1.0 1.0 49 P28072,Q13616,Q15008,O00487,P49721,P60900,P25787,P20618,Q14997,Q13404,O43242,Q13501,Q13200,O15111,P28066,P25789,O75832,P09429,Q00653,P49720,P61289 21 +Met promotes cell motility 0.3633715998278234 0.3409841176233619 0.7331155383084125 1.0 1.0 6 Q96N67 1 +G1 s dna damage checkpoints 0.4339368439620812 0.3409525448270005 0.7331393071327699 1.0 1.0 41 P28072,P42771,Q15008,O00487,P49721,P60900,P25787,P20618,Q14997,P20248,Q13315,O43242,Q13200,P28066,P25789,O96017,O75832,P49720,P61289 19 +Regulation of runx2 expression and activity 0.4332264647535735 0.3382953404139194 0.7351406347591036 1.0 1.0 42 P49721,P49841,P28072,Q13616,P60900,P25787,P20618,P28066,P49720,P61289,Q13309,Q14997,Q15008,O43242,O00487,Q13200,P25789,O75832 18 +Dna double strand break repair 0.416532022913651 0.338075423471073 0.7353063504992652 1.0 1.0 58 O60921,O96017,Q07864,P09874,Q99504,Q92547,P35244,P35251,Q13535,P28340,Q13315,P78527,P49005 13 +Downstream signaling events of b cell receptor bcr 0.4294228192089506 0.3337833232854434 0.7385430685248315 1.0 1.0 48 P28072,Q13616,Q08209,Q15008,O00487,O00221,P49721,P60900,P25787,P20618,Q14997,O43242,Q9UDY8,Q13200,P62942,O15111,P28066,P25789,O75832,P49720,P61289 21 +Cell cell junction organization 0.3726847850637426 0.3332119498881843 0.7389742983694123 1.0 1.0 9 Q8NI35,Q8TEW0 2 +Nephrin family interactions 0.3686911419737232 0.3321646946422565 0.7397649012669847 1.0 1.0 8 P46940,Q9Y5K6 2 +Signaling by alk in cancer 0.4280565460802416 0.3296354972439884 0.7416753974533938 1.0 1.0 34 Q9H6R7,Q13616,P28482,P31939,P35579,Q00610,P40763,P62753,Q13501,P26641,Q9NR09 11 +Tnfr2 non canonical nf kb pathway 0.4306160189485277 0.3284943281209522 0.7425379320869856 1.0 1.0 43 P28072,Q13616,P61081,Q15008,O00487,P49721,P60900,P25787,P20618,Q14997,Q8TBC4,O43242,Q13200,O15111,P28066,P25789,O75832,Q00653,P49720,P61289 20 +Degradation of gli1 by the proteasome 0.4300610284593349 0.3259912849260548 0.7444309489051779 1.0 1.0 40 P28072,Q13616,Q15008,O00487,P49721,P17612,P60900,P25787,P20618,Q14997,P62195,P55036,P25786,O43242,Q13200,P28066,O75832,P25789,P49720,P61289 20 +Regulation of tp53 activity 0.4114644835889051 0.3243252359047469 0.7456918158863455 1.0 1.0 59 P68400,Q92547,P35244,P31751,P54132,P42771,Q13526,Q8TBX8,Q12873,Q13535,Q00535,Q9UER7,O14965,Q14839,P20248,Q08945,P67870,P42345,P19784,Q13315,O14744,O60921,O96017,Q9Y5B9 24 +Dual incision in tc ner 0.4244542298304984 0.3195008677682244 0.7493467334613975 1.0 1.0 33 Q07864,P35244,P35251,P28340,P49005 5 +Pp2a mediated dephosphorylation of key metabolic factors 0.3444776119403036 0.3194771793685043 0.7493646936487464 1.0 1.0 3 P30154,Q14738 2 +Transcriptional regulation by runx2 0.4229339528893197 0.3188049418066568 0.7498744306530489 1.0 1.0 51 P49841,P28072,Q13616,P31751,Q15008,O00487,P49721,P60900,P25787,P20618,Q13309,Q14997,P14635,O43242,P11802,Q13200,P28066,P25789,O75832,P28482,P49720,P61289 22 +Scf skp2 mediated degradation of p27 p21 0.4277740945372203 0.3171699850651781 0.7511146234884865 1.0 1.0 40 P28072,Q13616,Q15008,O00487,P49721,P60900,P25787,P20618,Q13309,P20248,P62195,P55036,P25786,O43242,P11802,Q13200,P28066,O75832,P25789,P49720,P61289 21 +G alpha 12 13 signalling events 0.3785328694926058 0.3167487833094098 0.7514342294810246 1.0 1.0 12 Q9H8V3,Q13464,O75116,Q92974,Q14155 5 +Telomere c strand lagging strand synthesis 0.4059512250756187 0.3158187900296272 0.7521400551351385 1.0 1.0 22 P35251,P35244,P28340 3 +Assembly and cell surface presentation of nmda receptors 0.3739952440171249 0.3126571541007167 0.7545411506869075 1.0 1.0 11 P04350,Q13555,Q9BUF5,Q13885,Q15334 5 +Signaling by ptk6 0.3732565211439888 0.3100725634229921 0.7565057759250196 1.0 1.0 11 Q14185,P40763,P22681,P11802 4 +Stabilization of p53 0.4257285264395811 0.3093860977526334 0.757027844379266 1.0 1.0 40 O96017,P49721,P28072,P60900,P25787,P20618,P28066,P49720,P61289,P42771,Q14997,Q15008,Q13315,O43242,O00487,Q13200,P25789,O75832 18 +Degradation of dvl 0.4244162428278674 0.3083617088841416 0.7578071151332899 1.0 1.0 37 P28072,Q15008,O00487,P49721,P60900,P25787,P20618,Q14997,P62195,P55036,P25786,O43242,Q13200,P28066,O75832,P25789,P49720,P61289,Q13618 19 +Switching of origins to a post replicative state 0.4067588315435839 0.3035333061208146 0.7614834693177768 1.0 1.0 59 P28072,Q13616,P25205,Q15008,Q9UBD5,O00487,P33992,P49721,P60900,P25787,P20618,Q13309,Q14997,P20248,Q99741,P62195,P55036,Q9UJX5,Q9H1A4,P25786,P33991,O43242,Q13200,P33993,P28066,P25789,O75832,O43913,P49720,P61289 30 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.3523481377379789 0.301660258401949 0.7629110668851258 1.0 1.0 6 P49841 1 +Signaling by ctnnb1 phospho site mutants 0.3523481377379789 0.301660258401949 0.7629110668851258 1.0 1.0 6 P49841 1 +Beta catenin phosphorylation cascade 0.3523481377379789 0.301660258401949 0.7629110668851258 1.0 1.0 6 P49841 1 +Metabolism of polyamines 0.4224875104744798 0.2995072908418344 0.7645530099232125 1.0 1.0 38 P28072,Q15008,O00487,P49721,P60900,P25787,P20618,P19623,Q14997,P62195,P55036,P25786,O43242,Q13200,P28066,O75832,P25789,P49720,P61289 19 +Hedgehog off state 0.4168299741447012 0.2985765713033282 0.765263143835095 1.0 1.0 52 P49841,P28072,Q13616,Q15008,O00487,P49721,Q9BUF5,P17612,P60900,P25787,Q13885,P20618,Q14997,Q9Y496,P04350,O43242,Q13200,P28066,P25789,O75832,P49720,P61289 22 +Fc epsilon receptor fceri signaling 0.4073976414355443 0.2978661117260576 0.7658053534643408 1.0 1.0 58 P28072,Q13616,Q08209,Q13153,P19174,Q15008,O00487,P49721,P49427,P60900,P25787,P20618,Q14997,P62195,Q13404,P25786,O43242,Q9UDY8,Q13200,P25789,P28066,O75832,O15111,Q16512,P28482,P49720,P61289 27 +Tcr signaling 0.4164686342304218 0.297120652692074 0.7663743974028105 1.0 1.0 52 P28072,Q13616,Q13153,P19174,Q15008,O00487,P49721,P49427,P60900,P25787,P20618,Q14997,P62195,Q13404,P55036,P25786,O43242,Q9UDY8,Q13200,P25789,P28066,O75832,O15111,Q16512,P49720,P61289 26 +Signaling by notch1 0.3659619014272072 0.2969039216984448 0.7665398620268644 1.0 1.0 10 P49407 1 +Glycogen breakdown glycogenolysis 0.3618234195244798 0.2950268321883562 0.7679733823815658 1.0 1.0 9 P06737,Q93100,P46976,P35573,P11216 5 +Dna strand elongation 0.4074991200019285 0.2872728468034972 0.7739034119213677 1.0 1.0 27 P49005,P25205,P35244,P18858,P35251,P09884,P33991,P28340,P33993,P49642,P33992 11 +Cross presentation of soluble exogenous antigens endosomes 0.4176395310414837 0.2859052121080954 0.7749507216237441 1.0 1.0 36 P49721,P28072,P60900,P25787,P20618,P55036,P28066,P49720,O75832,Q14997,P61289,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 18 +Degradation of axin 0.4176395310414837 0.2859052121080954 0.7749507216237441 1.0 1.0 36 P49721,P28072,P60900,P25787,P20618,P55036,P28066,P49720,O75832,Q14997,P61289,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 18 +The role of gtse1 in g2 m progression after g2 checkpoint 0.4135326616273325 0.2773470900297959 0.7815136045435496 1.0 1.0 50 P28072,Q15008,O00487,P49721,Q9BUF5,P60900,P25787,Q13885,P20618,Q14997,P04350,P14635,O43242,Q13200,P28066,P25789,O75832,O95067,P49720,P61289,P53350 21 +Regulation of hmox1 expression and activity 0.4148242578975492 0.2705058544442834 0.7867711135620965 1.0 1.0 45 P28072,P68400,Q13616,Q15008,O00487,P49721,P60900,P25787,P20618,Q13309,Q14997,P67870,P19784,O43242,Q13200,P28066,P25789,O75832,P49720,P61289,Q13618 21 +Copi independent golgi to er retrograde traffic 0.4052257193665963 0.2689498077745429 0.7879683074852293 1.0 1.0 29 Q14203,P04350,P63167,Q9BUF5,Q13885,Q15042,Q14204,O43237,P47755,P43034,Q9NZ32 11 +Cyclin a cdk2 associated events at s phase entry 0.4145292197469747 0.2677220591311048 0.7889132687173879 1.0 1.0 42 P28072,Q13616,P31751,Q15008,O00487,P49721,P60900,P25787,P20618,Q13309,P20248,O43242,P11802,Q13200,P28066,P25789,O75832,P49720,P61289 19 +G2 m dna damage checkpoint 0.4133570771933973 0.2669659995794394 0.789495339671944 1.0 1.0 38 O96017,P30307,Q92547,P35244,P14635,Q13535,Q13315 7 +Asymmetric localization of pcp proteins 0.4115598352231387 0.262606451139665 0.7928539272487203 1.0 1.0 37 P49721,P28072,P60900,P25787,P20618,P55036,P28066,P49720,O75832,Q14997,P61289,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 18 +Signaling by erbb2 0.3622438170049088 0.261969381080418 0.7933450483742035 1.0 1.0 12 P40818,O60610,P31751,P61586 4 +Regulation of runx3 expression and activity 0.4107010856463173 0.2618680827959321 0.7934231473866482 1.0 1.0 36 P49721,P28072,P60900,P25787,P20618,P55036,P28066,P49720,O75832,P42771,P61289,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 18 +Cytosolic sensors of pathogen associated dna 0.3915035355212934 0.2594893873361228 0.7952576693505577 1.0 1.0 23 Q9NW08,O14802,P78527,O15111 4 +Egfr downregulation 0.3461299253625813 0.2556020920379324 0.7982581028414102 1.0 1.0 8 P60953,Q9UBC2,P22681 3 +Negative regulation of nmda receptor mediated neuronal transmission 0.3381984921958643 0.2547919401603483 0.798883800697485 1.0 1.0 6 Q14012,Q15334,Q92796,Q13555 4 +Rhob gtpase cycle 0.3852333979409515 0.2538382302094451 0.7996205370673983 1.0 1.0 21 Q9H2G2,Q16512,Q9H8V3,P63167,Q13464,O75116,Q92974,Q16513 8 +Heme biosynthesis 0.3378695217337327 0.2537528165706177 0.7996865274066611 1.0 1.0 6 P50336,Q7KZN9 2 +Hiv transcription elongation 0.393356956952008 0.2524338253319256 0.8007057576676122 1.0 1.0 25 Q9H3P2,Q08945,P18615,Q14241,Q9Y5B9,Q8IXH7,Q15370,Q15369,Q92759,P18074 10 +Caspase activation via death receptors in the presence of ligand 0.3282672310940746 0.2500570958098391 0.8025431946907673 1.0 1.0 4 P49327 1 +Regulation by c flip 0.3282672310940746 0.2500570958098391 0.8025431946907673 1.0 1.0 4 P49327 1 +Trna aminoacylation 0.4070792739478318 0.2476158085556865 0.8044316781185636 1.0 1.0 37 P47897,P49589,P26639,P07814,Q9H2U2,P41252,O43776,P23381,P54136,Q9NSD9,Q9P2J5,P26640 12 +Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.3394516112479411 0.2465461050125326 0.8052595189717211 1.0 1.0 7 Q13315 1 +Resolution of d loop structures 0.3394516112479411 0.2465461050125326 0.8052595189717211 1.0 1.0 7 Q13315 1 +Repression of wnt target genes 0.326664676022694 0.2450450370872236 0.8064215596126125 1.0 1.0 4 Q13363,Q04727,Q13547 3 +Cellular response to hypoxia 0.4078153025733112 0.2449413319147461 0.8065018580218042 1.0 1.0 41 P28072,Q15008,Q15369,O00487,P49721,P60900,P25787,P20618,Q14997,P62195,Q9GZT9,P55036,P25786,O43242,Q13200,P28066,O75832,P25789,P49720,P61289,Q15370 21 +Signaling by braf and raf1 fusions 0.3907064241962942 0.2440930729834975 0.8071587372777285 1.0 1.0 25 Q13555,P28482,O00203,O95352,P49407,Q99996,P46940 7 +Circadian clock 0.3529068286419201 0.2432990135785801 0.8077737684896513 1.0 1.0 11 P43490,Q15648,Q13616 3 +Apc c mediated degradation of cell cycle proteins 0.3980187200794033 0.2411103302821987 0.8094696065277405 1.0 1.0 55 P28072,Q13616,Q15008,O00487,P49721,O14965,P60900,P25787,P20618,Q13309,Q14997,P20248,P62195,P55036,Q9UJX5,Q9H1A4,P14635,P25786,O43242,Q13200,P25789,P28066,O75832,P28074,P49720,P61289,P53350,O43684 28 +Uptake and actions of bacterial toxins 0.3477319684718118 0.2381100849211971 0.8117957130290234 1.0 1.0 10 P36507,P13639 2 +Signaling by the b cell receptor bcr 0.4013152786383774 0.236044278776132 0.8133983112811458 1.0 1.0 51 P28072,Q13616,Q08209,Q15008,O00487,O00221,P49721,P60900,P25787,P20618,Q14997,O43242,Q9UDY8,Q13200,P62942,O15111,P28066,P25789,O75832,P49720,P61289 21 +Kinesins 0.3816269139403916 0.2355232931121423 0.8138026019775866 1.0 1.0 22 P04350,Q9BUF5,Q9BW19,Q13885,Q9Y496,Q96Q89,O00139,Q99661,O60333 9 +Myd88 independent tlr4 cascade 0.390792900417284 0.2280070728783582 0.8196407419777614 1.0 1.0 28 Q06124,P09429,Q14738,Q13616,P28482,Q13404,P51452,Q00653,Q15418,Q14790,Q9UHD2,Q6SZW1,Q16539,O15111 14 +Tp53 regulates transcription of cell cycle genes 0.3687662063212158 0.2266972274614939 0.820659183161738 1.0 1.0 18 O14965,P30307,Q9UIV1,A5YKK6,P20248,P14635,Q99873 7 +Cilium assembly 0.3871313956446848 0.2249331915382684 0.8220312477331457 1.0 1.0 59 Q3SYG4,P49368,Q92973,Q9UIS9,P18085,Q14203,P36405,Q9BUF5,P17612,P06493,Q13885,Q9Y496,Q14204,P17987,P04350,Q96KP1,Q8NCM8,P07437,O43924,Q9BT25,P43034,P63167,Q14008,Q15019,Q99996,Q7Z4H7,Q8TAG9,Q92538,Q7Z460,P53350,Q9BW83,Q96FJ2 32 +Mtor signalling 0.3639617206882705 0.2206765336471739 0.8253443044618711 1.0 1.0 17 Q15382,Q9Y478,Q04637,P42345,P31751,P62753,P62942,Q96B36 8 +Oncogenic mapk signaling 0.3895284999368069 0.2151834864336577 0.8296242652792538 1.0 1.0 30 Q13555,P28482,O00203,O95352,P49407,Q99956,P21359,Q99996,P46940 9 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.3556883126856644 0.2135954640086636 0.8308625369678113 1.0 1.0 15 Q13404,Q00653,Q96RD7,Q14790,O15111 5 +Negative regulation of notch4 signaling 0.3966708143068722 0.2114240303000096 0.8325564070630462 1.0 1.0 39 P49721,P28072,Q13616,P60900,P25787,P20618,P55036,P28066,P49720,O75832,P61289,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 18 +Tnfr1 induced proapoptotic signaling 0.3152272479743669 0.2109470305173053 0.83292860470528 1.0 1.0 4 Q6GQQ9 1 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3448225364707836 0.2096830115152139 0.8339150856286517 1.0 1.0 12 Q8IZH2 1 +Synthesis of bile acids and bile salts 0.3290127255428202 0.2047805333532786 0.8377435968393288 1.0 1.0 8 Q9BZF3 1 +Bile acid and bile salt metabolism 0.3290127255428202 0.2047805333532786 0.8377435968393288 1.0 1.0 8 Q9BZF3 1 +Advanced glycosylation endproduct receptor signaling 0.3278029935962967 0.2014395110939357 0.8403549229657405 1.0 1.0 8 P09429,P28482 2 +Sumoylation of immune response proteins 0.3074626865671681 0.201252714007517 0.8405009747792473 1.0 1.0 3 Q00653,Q04206 2 +Degradation of beta catenin by the destruction complex 0.3926318901965345 0.2001565967762315 0.8413581109896564 1.0 1.0 48 P49841,P28072,Q13616,Q15008,O00487,P49721,P60900,P25787,P20618,Q14997,P62195,Q04727,P55036,P25786,O43242,Q13200,P28066,O75832,P25789,P49720,P61289,Q14738 22 +Death receptor signalling 0.3813519334673634 0.1919962629177454 0.8477451327299128 1.0 1.0 30 O15111,Q96EP0,P98170,Q6GQQ9,Q9H8V3,P42574,Q14155,Q92974,P49327,Q96BN8,P61586,Q14790,Q13501,Q9Y5V3 14 +Glycogen metabolism 0.3378583552047308 0.1906988315021916 0.8487615542180067 1.0 1.0 12 P06737,Q93100,P46976,P35573,P11216,P13807 6 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.307554493878766 0.1897586058072941 0.8494982942387475 1.0 1.0 4 O43318,Q13404,P45985 3 +Interferon gamma signaling 0.340340340376239 0.1886491487184232 0.8503678092604046 1.0 1.0 13 Q06124,O75925,P29372,Q14258 4 +Signaling by hedgehog 0.3781208849413935 0.1879389274833703 0.850924526701903 1.0 1.0 58 P49841,P28072,Q13616,Q15008,O00487,P49721,Q9BUF5,P17612,P25787,Q13885,P20618,Q14997,Q9Y496,P04350,P49407,O43242,Q13200,P28066,P25789,O75832,P49720,P61289,Q13618 23 +Polymerase switching on the c strand of the telomere 0.3483827008742999 0.1856838252589505 0.8526927133024609 1.0 1.0 16 P35251,P28340 2 +Protein methylation 0.3181258213453249 0.1855593660180484 0.8527903212810912 1.0 1.0 7 P15880,P13639 2 +Ca dependent events 0.3139931832770657 0.1848108424744292 0.8533774032915009 1.0 1.0 6 Q13555,P28482 2 +Processing of dna double strand break ends 0.3753045940840591 0.1798633482145899 0.8572598497732751 1.0 1.0 29 Q92547,Q13535,P35244,Q13315 4 +Signaling by met 0.3451910893658401 0.1775002402715623 0.8591154765202298 1.0 1.0 16 Q06124,P22681,Q96P70,P40818,Q96N67 5 +Sumo is transferred from e1 to e2 ube2i ubc9 0.2982089552238832 0.176543129422207 0.8598672683674478 1.0 1.0 3 Q9UBT2,Q9UBE0 2 +Processing and activation of sumo 0.2982089552238832 0.176543129422207 0.8598672683674478 1.0 1.0 3 Q9UBT2,Q9UBE0 2 +Sumo is conjugated to e1 uba2 sae1 0.2982089552238832 0.176543129422207 0.8598672683674478 1.0 1.0 3 Q9UBT2,Q9UBE0 2 +Pten regulation 0.3521469093919108 0.1727544890907022 0.8628444115209704 1.0 1.0 68 P28072,P68400,Q13330,P31751,Q12873,Q15008,O00487,P49721,P98170,P25787,P20618,Q14839,O94776,Q14997,P67870,Q9HCE1,P42345,P19784,O43242,Q13200,P25789,P28066,O75832,Q15382,P28482,P49720,P61289 27 +Signaling by egfr 0.3298077296705216 0.1701549578598169 0.8648882735016354 1.0 1.0 12 Q06124,Q9UBC2,P22681,P60953,Q14155 5 +Mrna capping 0.3354858464364534 0.1609959914853228 0.8720965577893203 1.0 1.0 15 O60942 1 +Asparagine n linked glycosylation 0.1862268936039756 0.1604711903618169 0.8725099142704122 1.0 1.0 123 O14579,Q15436,P84085,P53618,Q13190,Q14203,Q9NR45,Q9UBF2,Q14746,O95394,Q9BUF5,Q14204,Q9Y296,Q96IJ6,Q9Y678,Q9Y6B6,Q06210,Q9NZ32,P04350,O15084,P53621,Q9UJ70,O43237,P47755,O95486,Q9BV10,P63167,Q96JB2,P61803,Q92538,Q9Y223,O00743 32 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3787415251107798 0.1590972180213015 0.8735922800020024 1.0 1.0 47 P28072,Q15008,O00487,P49721,O14965,P60900,P25787,P20618,Q13309,Q14997,P62195,P55036,Q9UJX5,Q9H1A4,P25786,O43242,Q13200,P28066,P25789,O75832,P49720,P61289,P53350 23 +Regulation of plk1 activity at g2 m transition 0.376204531804675 0.1584211653573594 0.8741249368298254 1.0 1.0 37 Q14203,P04350,O14965,P63167,O95067,Q13616,P17612,Q14008,Q99996,Q14204,P14635,Q7Z460,P53350,Q9BT25,P43034 15 +Hiv infection 0.1868773888703195 0.1534624450382928 0.8780336039726271 1.0 1.0 138 P28072,P30419,O75909,Q15008,Q9H3P2,Q15369,P49721,O14980,P18615,P25787,P20618,Q14241,Q14997,P18858,Q08945,Q9BXS5,P18074,P17096,P49917,O60942,O94973,Q8WUX9,Q5SRE5,O43242,Q13200,P28066,O75832,P49720,P61289,Q9Y5B9,Q99816 31 +Mrna decay by 3 to 5 exoribonuclease 0.3316674160382098 0.1521276407243965 0.8790862637810644 1.0 1.0 15 Q9Y2L1,Q6PGP7,Q9Y450,Q96C86,Q15477 5 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3694086182511899 0.1514431343836944 0.8796261655071635 1.0 1.0 33 Q14203,P04350,P63167,Q9BUF5,Q15185,Q14204,O43237,P47755,P31689,Q9NZ32 10 +Resolution of sister chromatid cohesion 0.3498806570886608 0.1491560033376645 0.8814305358094661 1.0 1.0 66 Q6P1K2,Q2NKX8,Q9P258,Q99661,O14980,Q9BUF5,P50748,Q14204,Q92674,P04350,Q29RF7,P14635,O43237,P63167,O95067,Q14008,Q9NTI5,Q9H900,Q7Z460,Q7Z5K2,P53350,Q14738 22 +Transcription of the hiv genome 0.3667327766447718 0.1481047978082542 0.8822600631025568 1.0 1.0 32 O60942,Q9H3P2,Q08945,P18615,Q14241,Q9Y5B9,O75909,Q15369,P18074 9 +P75 ntr receptor mediated signalling 0.3374414513782853 0.1457844271673375 0.884091569873604 1.0 1.0 18 Q9H8V3,Q9Y5V3,P42574,Q92974,Q13501,Q14155 6 +Generation of second messenger molecules 0.2918750292240135 0.14148455643545 0.8874871594942053 1.0 1.0 5 Q16512,P19174 2 +Semaphorin interactions 0.3517396301337274 0.1363700384645721 0.8915287582207831 1.0 1.0 26 Q16512,P60660,P49841,P35580,Q13464,P35579,O75116,Q13153,Q00535,P61586,Q9BPU6 11 +Intrinsic pathway for apoptosis 0.342962111448188 0.1358542284266247 0.8919365203281717 1.0 1.0 22 P63167,P28482,P42574,P30419,P31751,P42771,P40763,Q14790 8 +Nod1 2 signaling pathway 0.3038245743386689 0.1345210326411948 0.8929905806007863 1.0 1.0 9 Q14790,O15111,Q13404 3 +G protein beta gamma signalling 0.3001027122085139 0.1343098800217351 0.8931575409033676 1.0 1.0 8 Q16512,P60953,P61586,P31751 4 +Signaling by wnt in cancer 0.2998505231689167 0.1337819184451605 0.8935750256438242 1.0 1.0 8 P49841,P30154,Q13363,P56545,P30153,Q14738,P48729 7 +Hats acetylate histones 0.3521784696293255 0.1332913318889021 0.8939629825826945 1.0 1.0 27 Q96L91,Q9UPT9,Q9Y4A5 3 +Interconversion of nucleotide di and triphosphates 0.3275670142799518 0.1306547193409853 0.8960484539193696 1.0 1.0 17 P22392,P23921,Q9Y3D8,Q16881,P15531,P17812,P33316,P04818 8 +Signaling by insulin receptor 0.3266492704973128 0.1287867759960461 0.8975263696104305 1.0 1.0 17 Q06124,Q99570,P28482,P31751 4 +Intra golgi traffic 0.3139674589064122 0.1275209260683445 0.8985281117793409 1.0 1.0 13 Q96JB2,Q14746 2 +Ovarian tumor domain proteases 0.3035038206999838 0.1266365128785664 0.8992280964792321 1.0 1.0 10 Q96FW1,Q6GQQ9 2 +Recruitment of mitotic centrosome proteins and complexes 0.3567598900401191 0.1262464577773638 0.8995368375388408 1.0 1.0 32 Q14203,P04350,P63167,Q14008,P17612,Q99996,Q96CW5,Q14204,Q9BSJ2,Q7Z460,P53350,Q9BT25,P43034 13 +Signaling by ntrks 0.3574979371519684 0.1250991690560905 0.9004450411269505 1.0 1.0 33 Q06124,P36507,P28482,P51452,P46109,P50570,Q14839,O94973,Q15418,Q00610,P19174,Q00535,P40763,P61586,Q14738 15 +Extension of telomeres 0.3559791885429373 0.1246404024562515 0.900808241251872 1.0 1.0 32 P35251,O15084,P35244,P28340 4 +Loss of function of mecp2 in rett syndrome 0.2770976410868864 0.1194753682742767 0.904898753512098 1.0 1.0 4 P51608,Q13547,P17612 3 +Recruitment of numa to mitotic centrosomes 0.3578917147971098 0.1191892128140674 0.9051254526549471 1.0 1.0 36 Q14203,P04350,P63167,Q14008,Q9BUF5,P17612,Q13885,Q99996,Q96CW5,Q9BSJ2,Q14204,Q7Z460,P53350,Q9BT25,P43034 15 +Rho gtpases activate ktn1 0.2924678587652066 0.1189891205647642 0.9052839750754552 1.0 1.0 8 P84095,P60953,P63000,P61586,Q86UP2 5 +Signaling by vegf 0.3508129523580635 0.1171281551758722 0.9067584986885368 1.0 1.0 31 Q16512,Q13464,P42345,Q14185,O75116,P60953,P31751,Q9Y2A7,Q96F07,Q9UQB8,Q8WUW1 11 +Regulation of cholesterol biosynthesis by srebp srebf 0.3431202915749393 0.1151342844652468 0.9083386855140854 1.0 1.0 27 Q15648,Q13907,Q15436,Q13085,P49327,Q16850,O95486,P04035,Q9HCL2,Q9Y6B6 10 +Nucleotide excision repair 0.3573264494805827 0.1136737583620722 0.9094964154488924 1.0 1.0 52 O75925,Q07864,P09874,P35244,P35251,P28340,Q86WJ1,P18074,P49005 9 +Formation of tubulin folding intermediates by cct tric 0.3093836629824373 0.1126730867571394 0.9102897390043512 1.0 1.0 14 P04350,Q13509,Q9BUF5,P48643,Q13885,Q9BVA1,P49368,P68371,P17987 9 +Meiosis 0.3410432495891915 0.1112471710372037 0.9114203466710038 1.0 1.0 27 Q9UH99,Q13535,P35244 3 +Reproduction 0.3410432495891915 0.1112471710372037 0.9114203466710038 1.0 1.0 27 Q9UH99,Q13535,P35244 3 +Oxidative stress induced senescence 0.3229218157461823 0.1111443701376544 0.911501864397587 1.0 1.0 19 Q9HCE1,Q00534,P42771 3 +Mapk6 mapk4 signaling 0.3572836131436927 0.1102014468299428 0.9122496148598906 1.0 1.0 49 P28072,Q13153,Q15008,O00487,P49721,O14980,P17612,P60900,P25787,P20618,Q14997,P62195,Q9HCE1,P55036,P25786,O43242,Q13200,P28066,P25789,O75832,Q16512,P60953,P49720,P61289 24 +Interleukin 17 signaling 0.3237199830991416 0.1079171102577231 0.914061444365202 1.0 1.0 20 P28482,Q13616,P51452,Q15418,O15111 5 +Sealing of the nuclear envelope ne by escrt iii 0.296456237403006 0.1069393831624994 0.9148370690745642 1.0 1.0 11 P04350,Q8WUX9,Q9BUF5 3 +Glycogen synthesis 0.2775619958171428 0.1053484317482754 0.9160993337758 1.0 1.0 6 P36871,Q6PCE3,Q16851,P46976,P13807 5 +Senescence associated secretory phenotype sasp 0.3217110002021219 0.1001238043109117 0.9202460371814098 1.0 1.0 21 P28482,Q9UJX5,Q15418,P20248,P42771,P40763,Q00534 7 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.3506418032358878 0.0994882927022949 0.9207505828531416 1.0 1.0 40 P49721,P28072,P60900,P25787,P20618,P55036,P28066,P49720,O75832,Q14997,P61289,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 18 +Pentose phosphate pathway 0.2776449491930617 0.0990576222949943 0.9210925190500724 1.0 1.0 7 P37837,P52209,P29401,P11413,O95336,P11908 6 +Budding and maturation of hiv virion 0.2808018651607022 0.0981957580109321 0.921776850803648 1.0 1.0 8 Q8WUX9 1 +Apoptosis induced dna fragmentation 0.2867859544036405 0.0963814891321054 0.9232175932066092 1.0 1.0 10 P42574 1 +Apoptosis 0.2473472346839027 0.0954380163341385 0.9239669212057096 1.0 1.0 90 P30419,P31751,P42771,P49327,Q15008,Q9Y5V3,P49721,P25787,P20618,Q14997,P40763,P55212,P42574,P16402,O00429,O43242,Q13200,P28066,O75832,P63167,P09429,Q13464,P28482,P49720,P61289 25 +Regulation of lipid metabolism by pparalpha 0.3198136518674893 0.0930901135999582 0.9258319715348624 1.0 1.0 22 O75182,Q15648,Q9ULK4,Q96EK7,Q16881,Q9Y2X0,P04035 7 +Hedgehog ligand biogenesis 0.3454366468586741 0.0916286410718956 0.92699309488306 1.0 1.0 39 P49721,P28072,P60900,P25787,P20618,P28066,P49720,P61289,Q14997,Q15008,O43242,O00487,Q13200,P25789,O75832 15 +Toll like receptor tlr1 tlr2 cascade 0.3233723533154832 0.0915032711343728 0.9270927071532152 1.0 1.0 24 P09429,Q13616,P28482,P51452,Q00653,Q15418,Q14738,O15111 8 +Uch proteinases 0.3468034807060313 0.0894822640322214 0.9286986482865855 1.0 1.0 46 P49721,P28072,P60900,P25787,P20618,P28066,P49720,P61289,Q14997,P85037,Q15008,Q8NB78,O43242,O00487,Q13200,P25789,O75832 17 +Er to golgi anterograde transport 0.2867561784422062 0.0890756913456617 0.9290217560809796 1.0 1.0 80 O14579,Q15436,P84085,P18085,P53618,Q13190,Q14203,Q9UBF2,Q14746,Q9BUF5,Q13885,P55735,Q14204,Q9Y296,Q9Y678,Q9Y6B6,Q9NZ32,P04350,O15084,P53621,O43237,P47755,O95486,P63167,P53992,Q96JB2,O15027,Q92538,O00743 29 +Deadenylation dependent mrna decay 0.3440381733207986 0.0881997087235614 0.929717948821237 1.0 1.0 40 Q9UIV1,Q5TAX3,Q86TB9,Q8IZH2,A5YKK6,P26196,Q9Y2L1,Q6PGP7,Q14240,Q96C86,Q15477 11 +Endosomal sorting complex required for transport escrt 0.2743379145614902 0.0880038354223878 0.9298736277460892 1.0 1.0 8 Q8WUX9 1 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.3105595448651773 0.0864854968061453 0.931080484743749 1.0 1.0 20 P09429,Q00653,Q13526,Q9UII4,O15111,Q14258 6 +Transport to the golgi and subsequent modification 0.277730753750294 0.0847938013130116 0.9324253216287832 1.0 1.0 82 O14579,Q15436,P84085,P18085,P53618,Q13190,Q14203,Q9UBF2,Q14746,Q9BUF5,Q13885,P55735,Q14204,Q9Y296,Q9Y678,Q9Y6B6,Q9NZ32,P04350,O15084,P53621,O43237,P47755,O95486,P63167,P53992,Q96JB2,O15027,Q92538,O00743 29 +Deadenylation of mrna 0.3003791793007984 0.0834787512368786 0.9334708724675024 1.0 1.0 17 Q9UIV1,Q5TAX3,Q04637,A5YKK6,Q14240 5 +Anchoring of the basal body to the plasma membrane 0.3308722066864726 0.0830412473364214 0.9338187422240004 1.0 1.0 31 Q14203,P04350,P63167,Q14008,P17612,Q15019,Q99996,Q14204,Q7Z460,P53350,Q9BT25,P43034 12 +Defective cftr causes cystic fibrosis 0.3397474150470009 0.0814431169711315 0.9350895605926316 1.0 1.0 40 P49721,P28072,P60900,P25787,P20618,P28066,P49720,P61289,Q14997,Q15008,O43242,O00487,Q13200,P25789,O75832 15 +Abc transporter disorders 0.3397474150470009 0.0814431169711315 0.9350895605926316 1.0 1.0 40 P49721,P28072,P60900,P25787,P20618,P28066,P49720,P61289,Q14997,Q15008,O43242,O00487,Q13200,P25789,O75832 15 +Diseases associated with n glycosylation of proteins 0.2644949193066277 0.0791055400099919 0.9369486770341642 1.0 1.0 7 Q13724,Q2TAA5,Q9BT22,O75352,Q9BV10,O75340 6 +Rab regulation of trafficking 0.3296069527919393 0.0790318150377115 0.937007317458742 1.0 1.0 32 O95248,Q8TC07,Q15042,Q9Y296 4 +Golgi associated vesicle biogenesis 0.3260849305251281 0.0784438196270843 0.9374750178746116 1.0 1.0 30 O00203,P50570,Q8NC96,O00443,P49407,Q00610,Q01968,O14976,Q9Y5X3,Q9BXS5 10 +Telomere extension by telomerase 0.2789282390489443 0.0750876206427928 0.9401449973141612 1.0 1.0 12 O00743,O15084,P20248 3 +Glutathione synthesis and recycling 0.2574843816869217 0.0747118596981065 0.9404439713735562 1.0 1.0 6 Q96KP4,Q8WUX2,P48507 3 +Nef mediated cd8 down regulation 0.2563489692261656 0.0732416713877177 0.941613806442033 1.0 1.0 6 P63010,O94973,Q9UI12,O95782,Q96CW1 5 +Nef mediated cd4 down regulation 0.2563489692261656 0.0732416713877177 0.941613806442033 1.0 1.0 6 P63010,O94973,Q9UI12,O95782,Q96CW1 5 +Transcription coupled nucleotide excision repair tc ner 0.3350353476124053 0.0717093525911975 0.9428332130353696 1.0 1.0 44 Q07864,P35244,P35251,P28340,P18074,P49005 6 +Neurexins and neuroligins 0.2656169403835974 0.0711360057937645 0.9432895122646804 1.0 1.0 9 Q9HCM4 1 +Protein folding 0.3311990616874852 0.0703012499085038 0.9439538876874448 1.0 1.0 39 Q9H0D6,P04350,Q9BUF5,P68400,Q99426,P40763,P19784,P67870,Q9BTW9,Q9Y6D5,Q15477 11 +Rho gtpases activate cit 0.2741080418085489 0.0690421590136119 0.9449560615037428 1.0 1.0 12 Q15058,P35580,P35579,P61586,Q15334 5 +Rho gtpases activate formins 0.3188150122847857 0.0682451668833554 0.9455904727828376 1.0 1.0 64 Q6P1K2,P07737,Q2NKX8,Q9P258,O00139,Q99661,O14980,Q9BUF5,P50748,Q13885,O60610,Q14204,P61586,Q92674,P04350,O43237,P43034,P63167,Q14008,P60953,Q9H900,Q7Z460,P53350,Q14738 24 +Phospholipid metabolism 0.3313005600356435 0.0680943740896318 0.945710508789712 1.0 1.0 53 O96017,Q9NZC3,Q96T51,O15357,P35790,O00443,Q13614,P42356,Q01968,Q08AM6,P19784,Q12923,O95248,Q99570,P67870,Q9HCL2,Q8NCE2 17 +Aurka activation by tpx2 0.3208872431886915 0.067447366096113 0.94622556231803 1.0 1.0 32 Q14203,P04350,O14965,P63167,Q14008,P17612,Q99996,Q14204,Q7Z460,P53350,Q9BT25,P43034 12 +Auf1 hnrnp d0 binds and destabilizes mrna 0.3286320525311916 0.0650956047461996 0.9480978799166412 1.0 1.0 41 P49721,P28072,Q04637,P60900,P25787,P20618,P28066,P49720,P61289,Q14997,Q15008,O43242,O00487,Q13200,P25789,O75832 16 +Formation of rna pol ii elongation complex 0.3183289211232021 0.0643534363359446 0.9486888055503104 1.0 1.0 32 Q9H3P2,Q08945,Q7KZ85,P18615,Q14241,Q9Y5B9,Q8IXH7,O75909,Q15370,Q15369,Q92759,P18074,Q9GZS3 13 +Regulation of tp53 activity through acetylation 0.2792664747473069 0.0640414546408893 0.9489372185056142 1.0 1.0 15 Q14839,Q13526,P31751,Q8TBX8,Q12873 5 +Association of tric cct with target proteins during biosynthesis 0.2890608027575359 0.0622205588217374 0.950387190636352 1.0 1.0 19 Q9Y6D5 1 +Regulated necrosis 0.2879501645108065 0.0610141638486252 0.951347928952056 1.0 1.0 19 P42574,P09429,Q8WUX9 3 +Post translational protein modification 0.1729369275420941 0.0606010304048605 0.9516769528898916 1.0 1.0 405 Q70CQ2,Q9UPT9,Q13616,P09874,Q93008,P42771,P53618,Q15008,Q12873,Q13190,P26358,Q15369,Q9Y4A5,Q9HA64,Q9UER7,Q9H2P9,Q9UBF2,P49721,Q14746,P15880,Q86VP6,Q14999,P49427,O14965,P25787,Q9NR45,Q86UV5,Q14997,Q13309,Q96BN8,Q14204,Q5TAQ9,Q8NB78,P20248,Q9Y296,Q96IJ6,Q13564,Q9Y678,Q9Y6B6,P78527,Q9Y3I1,Q9NZ32,P04350,Q06210,Q6GQQ9,O15084,P53621,O43505,P49407,Q9UJ70,Q96RU2,O43237,Q5SRE5,P47755,O43242,Q9BV10,Q96FW1,P28066,Q14258,O75925,O60826,Q96JB2,P40818,P61803,P49720,P61289,P63241,P85037,Q92538,Q14527 70 +Recycling pathway of l1 0.2939900010398083 0.0567910189348592 0.954711668244714 1.0 1.0 23 P04350,Q9BUF5,P28482,Q13885,P35241,P50570,O94973,Q15418,Q00610 9 +Toll like receptor 9 tlr9 cascade 0.3000704167598729 0.0561992083766332 0.9551831117918516 1.0 1.0 26 P09429,Q13616,P28482,P51452,Q00653,Q15418,Q99570,Q14738,O15111 9 +Signaling by notch4 0.3210523895318407 0.0554680344938566 0.9557655955078646 1.0 1.0 42 P49721,P28072,Q13616,P60900,P25787,P20618,P55036,P28066,P49720,O75832,P61289,P25786,Q15008,O43242,O00487,Q13200,P25789,P62195 18 +Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.2580698595582801 0.0552694665823316 0.9559237871086615 1.0 1.0 11 Q10567,O94973,O95782,Q9BXS5 4 +Eph ephrin signaling 0.3095338055997806 0.0547167298611794 0.9563641408275176 1.0 1.0 32 Q16512,P60660,P35580,Q13464,P35579,O75116,P60953,O94973,Q00610,O95782,P61586,O00401,Q14155 13 +Rho gtpases activate paks 0.263422098125324 0.0541229060315125 0.9568372426177774 1.0 1.0 13 Q16512,P60660,P35580,P35579,P60953 5 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.273681055155879 0.0523655748244187 0.9582374037760985 1.0 1.0 17 P61758,P04350,P50991,Q99471,Q13509,Q9UHV9,P48643,Q9BUF5,Q13885,Q9BVA1,P49368,P17987,P78371,P68371,P40227,Q99832 16 +Phosphorylation of the apc c 0.2526080827936451 0.0502695994116374 0.959907549284252 1.0 1.0 11 P14635 1 +Vegfr2 mediated vascular permeability 0.2521590296225267 0.0498815667743727 0.9602167665984278 1.0 1.0 11 P31751,P42345 2 +Transcriptional regulation by runx3 0.3144758300764064 0.0494036368628059 0.9605976299056752 1.0 1.0 41 P49721,P28072,P25440,P25787,P20618,P60900,P28066,P49720,P61289,P42771,Q15008,O43242,O00487,Q13200,P25789,O75832 16 +Signalling to erks 0.2476556723672826 0.0489393852704571 0.9609676015441062 1.0 1.0 10 P36507,P28482 2 +L1cam interactions 0.31554514056564 0.0482924727685627 0.9614831534168112 1.0 1.0 45 O95239,P36507,P68400,O95782,Q9BUF5,Q13885,P35241,P67870,Q92796,P04350,Q96P70,P50570,O94973,Q15418,Q00610,P19784,Q16512,P28482,Q96S59,Q15334 20 +Myogenesis 0.2348409019894113 0.0471457505351686 0.9623970642004228 1.0 1.0 7 O60271 1 +Copi mediated anterograde transport 0.3089839046391324 0.0442148303573394 0.9647331606986764 1.0 1.0 57 O14579,Q9UBF2,Q14746,Q14203,P04350,Q9BUF5,P53621,P63167,P84085,Q96JB2,P53618,Q14204,O43237,Q13190,P47755,Q92538,Q9Y678,Q9NZ32 18 +Signaling by notch 0.3082363728091634 0.0434702760589741 0.9653266583885654 1.0 1.0 57 P49721,Q9HCE1,Q15398,Q13616,P67809,P25787,P20618,P49407,P61289,P49720,Q15008,O43242,Q13200,P28066,O75832 15 +Mhc class ii antigen presentation 0.308937628491141 0.0434550771673828 0.9653387739009742 1.0 1.0 56 Q15436,O95782,O00139,Q99661,Q14203,Q9BUF5,Q13885,Q9Y496,Q14204,Q10567,Q9Y6B6,Q9BXS5,Q9NZ32,P04350,P50570,O94973,Q00610,O43237,P47755,O95486,P63167,P53992 22 +Rab gefs exchange gtp for gdp on rabs 0.2849354077980043 0.0413508939612983 0.9670161602256298 1.0 1.0 27 O95248,Q15042,Q9Y296 3 +Activation of gene expression by srebf srebp 0.2655144248621518 0.0394610126711454 0.9685228366716914 1.0 1.0 20 Q15648,Q13907,Q13085,P49327,P04035,Q9HCL2 6 +Formation of the early elongation complex 0.2567239784005192 0.039207205578392 0.9687251888345014 1.0 1.0 17 P18615,Q8IXH7,Q9H3P2,Q92759,P18074 5 +Translation of sars cov 2 structural proteins 0.257822040221639 0.0380736192301586 0.9696289848592736 1.0 1.0 18 Q96SB4,P78362,P61803,Q99873 4 +Pcp ce pathway 0.3035468600169479 0.037112281704812 0.9703954793910664 1.0 1.0 49 P28072,Q15008,P07737,O95782,O00487,P49721,P60900,P25787,P20618,Q14997,P61586,O94973,Q00610,O43242,Q13200,P25789,P28066,O75832,P49720,P61289 20 +Transcriptional regulation by runx1 0.2856386132880924 0.0369366093965842 0.9705355495756988 1.0 1.0 69 P68400,P51532,Q15008,Q9HCL2,P49721,P25787,Q14997,Q00534,P67870,Q99873,Q06124,Q9HCE1,P19784,O43242,P28066,O75832,O75182,P49720,P61289 19 +Cell cell communication 0.2775215445112455 0.0363974146187445 0.9709654756505292 1.0 1.0 27 Q06124,Q8NI35,Q8TEW0,P46940,Q9Y5K6 5 +Golgi to er retrograde transport 0.2762298496139829 0.0358964104893385 0.9713649580391353 1.0 1.0 73 O14579,P84085,P18085,P53618,Q99661,Q9UBF2,Q14203,Q9BUF5,Q13885,Q9Y496,Q14204,Q9Y678,Q9NZ32,P04350,P53621,Q96Q89,O43237,P47755,O60333,P43034,P63167,Q9BW19,Q15042,Q92538,Q15102 25 +Trafficking of ampa receptors 0.2301459062148757 0.0347326117598755 0.9722929561844036 1.0 1.0 11 Q9UM54,Q15334,O94973,Q13555 4 +Defects in vitamin and cofactor metabolism 0.2296409705216993 0.0344659625888334 0.9725055841328096 1.0 1.0 11 Q99707 1 +Sensory perception 0.2678507959205646 0.0333918517554315 0.9733621073980504 1.0 1.0 25 P35579,P30419,P50579,P47755,P29375 5 +Sema3a pak dependent axon repulsion 0.2158445440956716 0.0328164153171905 0.9738209877328892 1.0 1.0 8 Q16512,Q9UIW2,P63000,Q13153,P08238,P23528,P07900 7 +G0 and early g1 0.2101341660965272 0.0318546273287001 0.9745879824058687 1.0 1.0 7 P20248 1 +Amino acids regulate mtorc1 0.23721877999914 0.0317567589770777 0.9746660305657612 1.0 1.0 15 Q15382,Q9Y5K8,P42345,O75348,Q9P0V3 5 +Factors involved in megakaryocyte development and platelet production 0.2957996145115782 0.0317343163806561 0.9746839281462728 1.0 1.0 49 Q92908,P04350,Q9H4M9,Q9BUF5,P17612,Q9BW19,Q14185,Q13885,Q9NRW7,P60953,Q13572,Q96N67,Q9Y496,Q00535,Q96Q89,P47755,Q99661,O60333 18 +Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.2312580030658841 0.0305047400301375 0.9756645131444346 1.0 1.0 14 P19784 1 +Trna processing 0.2814594851695476 0.0302484020942288 0.9758689468843308 1.0 1.0 67 P57081,Q2VPK5,Q9UET6,Q96FX7,P07814,O43592,O75818,Q99575,O15091,Q5SRE5,Q8TEA1,Q9UJA5,O60294,Q7Z4G4,Q9UBP6 15 +Trans golgi network vesicle budding 0.2798464490769132 0.0289157284077198 0.9769318014117644 1.0 1.0 36 P20645,O00203,P50570,Q8NC96,O00443,P49407,Q00610,Q01968,Q92538,O14976,Q9Y5X3,Q9BXS5 12 +Sars cov 2 infection 0.2533355885957563 0.0288097520564542 0.9770163230931548 1.0 1.0 23 P78362,P61803,Q8WUX9,Q99570,Q96SB4,Q99873 6 +Protein ubiquitination 0.259674378701352 0.0283901502535945 0.9773509799953836 1.0 1.0 26 Q93008,Q14527,P78527,P49427 4 +Synthesis of substrates in n glycan biosythesis 0.231607215447137 0.0280928258248983 0.9775881159792036 1.0 1.0 16 Q9NR45,Q9UJ70,Q9Y223,Q96IJ6,Q06210 5 +Nonhomologous end joining nhej 0.239767788135604 0.0267216884428253 0.9786817144318514 1.0 1.0 20 P78527,Q13315 2 +Energy dependent regulation of mtor by lkb1 ampk 0.203084281859453 0.0264484305671388 0.9788996656375069 1.0 1.0 9 Q15382,P42345 2 +Toll like receptor cascades 0.268712358060035 0.0262024628749202 0.9790958514680612 1.0 1.0 33 Q06124,P09429,Q14738,Q13616,P28482,Q13404,P51452,P50570,Q00653,Q15418,Q99570,Q14790,Q9UHD2,Q6SZW1,Q16539,O15111 16 +The role of nef in hiv 1 replication and disease pathogenesis 0.2161676646706596 0.026146203620514 0.9791407244847594 1.0 1.0 13 P63010,P56377,P04439,P63000,O94973,Q9UI12,O43747,Q96CW1,O95782,Q10567,Q9BXS5,P53680 12 +Telomere maintenance 0.2780192027679221 0.0252750890456719 0.9798355436440958 1.0 1.0 41 O15084,P35244,P35251,P28340,Q9UER7,P49005 6 +Cell junction organization 0.2251237633756098 0.0249155668929664 0.9801223105038744 1.0 1.0 17 Q8NI35 1 +Metabolism of water soluble vitamins and cofactors 0.2780624914062288 0.0248593557104274 0.9801671466509756 1.0 1.0 42 P00374 1 +Autophagy 0.2801437379977275 0.0234206914659327 0.9813147001291038 1.0 1.0 56 P04350,Q9NT62,P42345,Q9Y4P1,O95352,Q8WUX9,Q14204,P19784,O43237,Q13315,P67870,Q13501,Q8NCE2,Q99816 14 +Metabolism of nucleotides 0.2773458753938962 0.0225381770056672 0.9820186588800006 1.0 1.0 49 P00492,P07741,O15067,P23921,P04183,P11172,Q96DE0,Q9Y3Z3,P20839,P15531,P17812,P27708,Q9P2T1,P33316,Q9Y3D8,Q16881,P22392,P31939,Q08623,Q01433,P04818,Q9UKK9 22 +Activation of nmda receptors and postsynaptic events 0.2438550200986455 0.02234559107551 0.982172281530078 1.0 1.0 27 P04350,Q13555,Q9BUF5,P17612,P28482,Q13885,Q15418,Q15334,Q92796,Q14155 10 +Rhoc gtpase cycle 0.2506261770435729 0.022263210878813 0.982237995069294 1.0 1.0 30 Q9H2G2,Q16512,P63167,Q13464,O75116,O60610,Q16513,P46940,Q13190 9 +Sensory processing of sound by outer hair cells of the cochlea 0.1940119760479073 0.021147529626707 0.983127970200365 1.0 1.0 13 P35579,P35241,Q01082,Q00013,Q13813,Q6IBS0,O00159,Q14651,P26038,P15311,Q12792,Q9Y2J2 12 +Cytoprotection by hmox1 0.2666435065036454 0.0204932207799184 0.9836499199761564 1.0 1.0 66 O75880,Q15648,P68400,Q13616,Q15008,P49721,P25787,P20618,Q13309,Q14997,P40763,P67870,P19784,O43242,Q13200,P28066,O75832,O75182,P49720,P61289,Q13618 21 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.220287095539659 0.0203397276098349 0.9837723642845964 1.0 1.0 22 Q9NR45,Q9UJ70,Q9Y223,Q96IJ6,Q9BV10,Q06210 6 +Mitotic spindle checkpoint 0.2710952791246072 0.0198486265954161 0.9841641270976736 1.0 1.0 57 P63167,O14980,Q14008,Q14738,P50748,Q9UJX5,Q6P1K2,Q9H900,Q14204,Q7Z460,Q2NKX8,O43237,P53350,Q92674,Q9P258,O00139,Q99661,P43034 18 +Abortive elongation of hiv 1 transcript in the absence of tat 0.1814914645103277 0.019207630374241 0.9846754705681796 1.0 1.0 14 Q8WX92,P18615,O00267,P13984,Q8IXH7,Q09161,P62487,P35269,Q9H3P2,P24928,P19387,P62875,P30876 13 +Abc family proteins mediated transport 0.2677356495642692 0.0191905152005485 0.9846891239844376 1.0 1.0 50 Q8NE71,P49721,P28072,P60900,P25787,P20618,P28066,P49720,P61289,Q14997,P25786,Q15008,O43242,O00487,Q13200,P25789,O75832 17 +Metabolism of vitamins and cofactors 0.2680475605660239 0.0191322372920513 0.9847356144923844 1.0 1.0 51 P00374,O00764,Q99707,P49327,P29375 5 +Beta catenin independent wnt signaling 0.2667163022854179 0.0184450973874977 0.9852837760396618 1.0 1.0 58 P28072,Q08209,Q15008,O95782,P07737,O00487,P49721,P25787,P20618,Q14997,P61586,Q9HCE1,O94973,Q00610,O43242,Q13200,P25789,P28066,O75832,P49720,P61289 21 +Mitochondrial trna aminoacylation 0.1836926814977778 0.0180182621429448 0.985624284692468 1.0 1.0 18 P47897,P26640 2 +Ripk1 mediated regulated necrosis 0.1476489967055984 0.0177033535185031 0.9858755053469834 1.0 1.0 14 O00560,O75955,O15294,P98170,Q8WUM4,Q14254,P49327,Q16543,Q12933,Q9UNE7,Q14790,Q13546,P07900 13 +Leishmania infection 0.2528241689209551 0.0174030523811753 0.986115074076954 1.0 1.0 43 P28482,P17612,Q14185,Q9UQB8,P35579,P60953,Q00653,P19174,Q9NZQ3,Q9Y2A7,Q96F07,Q7L576,O00401,Q8WUW1 14 +Signaling by fgfr2 0.181927349144396 0.016886912792103 0.986526833358868 1.0 1.0 22 Q01085,P19174,P19387,P30153,P62875,P26599,P62993,P62487,P52272,P31943,Q06124,P13984,Q09161,P52597,P35269,P24928,P09651,P28482,P22681,P30876,P27361 21 +Signaling by fgfr 0.181927349144396 0.016886912792103 0.986526833358868 1.0 1.0 22 Q01085,P19174,P19387,P30153,P62875,P26599,P62993,P62487,P52272,P31943,Q06124,P13984,Q09161,P52597,P35269,P24928,P09651,P28482,P22681,P30876,P27361 21 +Rac1 gtpase cycle 0.2522309988875736 0.0163293433883564 0.9869716480211056 1.0 1.0 47 Q16512,Q9H8V3,P63167,Q14185,P60953,Q96N67,Q16513,P46940,Q9Y2A7,Q96F07,Q9UQB8,O00401,Q8WUW1,Q14155 14 +Phase ii conjugation of compounds 0.2100868106165484 0.0162922181637299 0.9870012657246175 1.0 1.0 30 Q8WUX2,Q96KP4,O60701,Q9UI30,P21266,O95861,P14550,Q9NZL9,P31153,P48506,P10768,P23526,P51580,P48507,Q96IU4,Q9HBK9,P78417,Q99707,P28161,O43252 20 +Formation of tc ner pre incision complex 0.1820913461538473 0.0162378561796673 0.9870446345753652 1.0 1.0 25 Q93009,Q9UNS2,Q92905,Q13619,P19387,O60306,P62875,Q92759,Q9BT78,Q9UMS4,P62487,P18074,Q9HCS7,Q99627,Q9UNP9,P24928,P19447,P23193,Q7L5N1,Q13098,P61201,Q16531,Q13620,P30876 24 +Translocation of slc2a4 glut4 to the plasma membrane 0.2388535936018901 0.0161450278345674 0.9871186911706205 1.0 1.0 40 P04350,Q96KP1,Q9BUF5,Q9UIQ6,P35579,Q13885,P31751,Q9Y496,Q8TAG9,Q86X10,O60343 11 +Regulation of mrna stability by proteins that bind au rich elements 0.2565585607885342 0.0158779370704858 0.9873317714517932 1.0 1.0 62 P49721,O14980,Q04637,P25787,P20618,Q8IZH2,P49720,Q92973,Q14997,Q9Y2L1,P61289,Q15008,O43242,Q13200,P28066,O75832 16 +Antigen processing cross presentation 0.2546388125630039 0.015727658594272 0.9874516613567796 1.0 1.0 53 P28072,Q9UIQ6,Q15008,O00487,P49721,P25787,P20618,Q03518,Q14997,O43242,Q13200,O15111,P28066,P25789,O75832,P09429,P49720,P61289,P60059 19 +Cdc42 gtpase cycle 0.2076825930901198 0.0152241977987548 0.9878533168462516 1.0 1.0 34 Q16512,Q9H8V3,P63167,P60953,Q96N67,Q6XZF7,P46940,Q9UQB8,Q14155 9 +Copii mediated vesicle transport 0.1677294954694946 0.0146190664493031 0.9883360880511431 1.0 1.0 33 Q9UPN7,O15084,P53992,Q15436,P55735,O15027,Q5H9R7,Q13190,O95486,Q9Y296,Q9Y6B6,O00743 12 +Copi dependent golgi to er retrograde traffic 0.2367499213859339 0.0138023597425029 0.9889876599111416 1.0 1.0 50 O14579,Q9UBF2,P04350,Q9BUF5,P53621,Q9BW19,P84085,Q9Y496,P53618,Q96Q89,Q92538,Q9Y678,Q99661,O60333 14 +Cellular senescence 0.224037752817631 0.0136099624495532 0.9891411563219829 1.0 1.0 46 P17096,Q9HCE1,P28482,Q9UJX5,Q96L91,Q15418,P16402,P20248,P42771,P40763,Q13315,Q00534 12 +Chromosome maintenance 0.2136279283026743 0.0128142933091997 0.989775953020258 1.0 1.0 48 P35251,O15084,P35244,P28340 4 +Cellular response to chemical stress 0.2265962927431996 0.0118231187143074 0.9905667358910836 1.0 1.0 76 O75880,Q15648,P68400,Q13616,Q15008,P49721,P25787,P20618,Q13309,Q14997,P40763,P67870,Q16881,P19784,O43242,Q13200,P28066,O75832,O75182,P49720,P61289,Q13618 22 +Chromatin modifying enzymes 0.2201986247748001 0.0108383370215898 0.9913524275304336 1.0 1.0 77 Q9UPT9,Q9UPP1,P51532,Q12873,Q9Y4A5,P15880,O95163,Q96L91,Q14839,Q86TU7,Q8NB78,P29375,Q99873,Q9H9T3,O14929,O60678,P11802,O14744,Q9Y6J9,Q8IUF8,Q7LBC6 21 +Hiv life cycle 0.1931351464564588 0.0081304887035182 0.9935128800634374 1.0 1.0 82 P17096,P49917,O60942,Q9H3P2,O14980,Q14241,Q8WUX9,P30419,P18858,O75909,Q5SRE5,Q15369,P18074,Q99816 14 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c19ef47b15e0de5295e6e2169434c5233fb8d047 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the phototransduction cascade", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Olfactory signaling pathway", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pou5f1 oct4 sox2 nanog repress genes related to differentiation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory perception of taste", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 dependent activation of irf3 irf7", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trail signaling", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns"], "available_proteins": ["AAAS", "AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD28", "ANLN", "ANO10", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC8", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATR", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCL10", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRK1", "BSG", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CENPF", "CENPI", "CENPK", "CERS1", "CERS2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG7", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1A", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EGLN1", "EHD1", "EHHADH", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FIP1L1", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FOXK1", "FOXK2", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS1", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKG", "ILF2", "ILK", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCA2", "ISCU", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMD1", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LRRC8A", "LRRC8C", "LRRFIP1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MALT1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "MFN1", "MFN2", "MGA", "MGAT1", "MGAT5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLXNA1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RELA", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX2", "RIPK1", "RNASET2", "RNF2", "RNF20", "RNF31", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SBF1", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHD", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC3A2", "SLC5A6", "SLC7A11", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOD2", "SORD", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX4", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCP1", "TDP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126B", "TMF1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBR1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASL", "WBP11", "WDCP", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZFYVE16", "ZNF512B", "ZNF638", "ZNF703", "ZW10", "ZWILCH", "ZZZ3"], "leading_proteins": ["AASDHPPT", "ABCE1", "ABCF1", "ABHD14B", "ACACA", "ACLY", "ACTR10", "ACTR2", "AGL", "AHCY", "AIP", "AK6", "AKAP9", "AKR1A1", "AKT1S1", "AKT2", "ALDOC", "ALG1", "ALG11", "ALG12", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC4", "ANKRD28", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "APEX1", "APRT", "AQR", "ARF4", "ARF5", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARL3", "ARRB1", "AS3MT", "ASCC3", "ASNS", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATR", "AURKA", "B4GAT1", "BAIAP2", "BBS9", "BIRC6", "BLM", "BPNT1", "BRD2", "BRK1", "BUB3", "BUD23", "CAD", "CAMK1", "CAMK2G", "CAND1", "CAPZA2", "CARS", "CASP3", "CASP6", "CASP8", "CBL", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CD2AP", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC6", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDKN2A", "CENPI", "CFL1", "CHAC2", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHKA", "CHM", "CHMP7", "CHTOP", "CHUK", "CIAO1", "CKAP5", "CKB", "CLASP1", "CLTC", "CNDP2", "CNOT1", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COPA", "COPB1", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "CORO1A", "COX15", "CRKL", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTPS1", "CTU2", "CUL1", "CUL3", "CUL4A", "CUL4B", "CUL7", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAXX", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DDA1", "DDB1", "DDX1", "DDX46", "DDX6", "DHFR", "DHX16", "DHX37", "DHX38", "DIAPH1", "DIS3", "DLG3", "DLGAP5", "DNAJA1", "DNAJB11", "DNAJC13", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DOCK7", "DPH2", "DPH5", "DPYSL5", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "ECT2", "EDC3", "EEF1A2", "EEF1G", "EEF2", "EGLN1", "EHD1", "EIF2B2", "EIF2B5", "EIF3A", "EIF3D", "EIF4A2", "EIF4G1", "EIF4G3", "EIF5A", "EIF5B", "ELOA", "ELOB", "ELOC", "ELP1", "ELP3", "EP400", "EPB41L3", "EPB41L5", "EPRS", "EPS15L1", "ERCC2", "ERCC3", "ERCC6L", "ESD", "ESPL1", "EXOC2", "EXOC6", "EYA3", "EZR", "FAM120B", "FANCI", "FARSB", "FASN", "FAU", "FBXO7", "FEN1", "FKBP1A", "FLOT1", "FLOT2", "FN3KRP", "FOXK1", "FTSJ1", "FTSJ3", "G6PD", "GAK", "GAMT", "GART", "GATA6", "GBF1", "GCLC", "GCLM", "GCN1", "GDE1", "GEMIN4", "GFPT1", "GLMN", "GMPPA", "GMPR2", "GMPS", "GNE", "GPAM", "GPHN", "GPI", "GPKOW", "GPS1", "GRB2", "GSK3B", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2F2", 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a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..778d069f19cbf4c1874a831caa9e6ec0e928153d --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..187fc1553d6f772ea0887087c59f4da1e9a54296 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,304 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytoplasmic ribosomal proteins 0.684144382128732 3.0062763418454033 0.002644685304646 0.7931315623143071 0.0665405133021407 76 P18621,P08708,Q07020,P62847,P46782,P61353,P46776,P40429,P62424,P62861,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P36578,P60866,P62851,P62906,P61313,P62854,P62753,P50914,P62910,P26373,P18124,P62266,P61513,P39023,P61254,P62899,Q9Y3U8 47 +Atr signaling 0.8943794308005675 2.9462586205245196 0.0032164334895627 0.8529323084684952 0.0712011545805305 4 Q92547,Q13535 2 +Pilocytic astrocytoma 0.8637904645202374 2.827751705174016 0.0046876148376429 0.9389271897062768 0.0747397396755443 3 P21359 1 +Erk pathway in huntingtons disease 0.8616308600940381 2.7982617678900703 0.005137845505148 0.9533414142297034 0.0764254518890774 4 P42574,P42858 2 +Hostpathogen interaction of human coronaviruses autophagy 0.8521946849805909 2.7551351047813193 0.0058667904155105 0.969833409586347 0.0827216392498078 4 Q9NT62,O95352,P42345 3 +Leptininsulin signaling overlap 0.8325872873768976 2.706126696681139 0.0068073069261562 0.9828232144742254 0.0838240705480756 2 O14654 1 +Type ii diabetes mellitus 0.831464199689258 2.679912641908114 0.0073641375860782 0.9876965441270906 0.0876332372743309 3 P28482 1 +Estrogen receptor pathway 0.8110370292241778 2.5851562150791807 0.009733488623381 0.9970317875010226 0.1113735717483027 3 Q9HCL2 1 +Kallmann syndrome 0.8079222053934656 2.529986235351979 0.0114067001472717 0.9989148011614924 0.1211961890647622 5 Q06124,Q9P2D1,P28482 3 +Relationship between inflammation cox2 and egfr 0.7874672446591617 2.474523501048099 0.0133414042905717 0.999661695517417 0.1345446703879692 3 P28482 1 +15q112 copy number variation syndrome 0.7641086891609374 2.341918063760475 0.0191849261928283 0.9999901294037096 0.1678681041872476 4 Q96CW5,Q9BSJ2,Q06787 3 +Hedgehog signaling pathway wp4249 0.7660947178905712 2.3307647357230064 0.0197657685554806 0.9999930614372255 0.1680090327215853 5 Q9Y496,P49407,P17612 3 +Insulin signaling in adipocytes diabetic condition 0.7503716304509228 2.2757359091384566 0.0228618207487789 0.9999989436456024 0.1741261023337525 4 P62753,P31751 2 +Insulin signaling in adipocytes normal condition 0.7503716304509228 2.2757359091384566 0.0228618207487789 0.9999989436456024 0.1741261023337525 4 P62753,P31751 2 +Interactions between immune cells and micrornas in tumor microenvironment 0.7394807520143188 2.267766761402135 0.0233434263021141 0.999999212197864 0.1741261023337525 2 P40763 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.7420895522388086 2.257599601297716 0.023970633540308 0.9999994624530004 0.1741261023337525 3 P49841,P42345 2 +Nad metabolism 0.7463901756043478 2.2564669767941243 0.0240414011935032 0.9999994851509424 0.1741261023337525 4 Q8IXJ6,P09874 2 +Nonhomologous end joining 0.7413410863910715 2.231974997237574 0.0256166154686083 0.9999998030878864 0.1772312349281626 4 P78527 1 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.7297645145714935 2.197793873748111 0.0279637982160483 0.9999999531130848 0.183936445355635 3 P28482 1 +Immune response to tuberculosis 0.7212462195302343 2.1338836672289827 0.0328523047673898 0.9999999976653772 0.1999605725049632 4 O75925,Q03518 2 +Interleukin1 induced activation of nfkb 0.7117278424350819 2.1328786456272484 0.0329346825302292 0.999999997780752 0.1999605725049632 2 Q13501 1 +Phosphodiesterases in neuronal function 0.7033721277230646 2.0918955238453805 0.0364478625987421 0.9999999997454604 0.211048993261795 2 O43924 1 +Base excision repair 0.7354179271214568 2.0277312497269206 0.0425876844362771 0.9999999999943258 0.2324740572438981 15 P09429,P27695,Q07864,P29372,P09874,P28340,P49005 7 +Airway smooth muscle cell contraction 0.693526095268014 1.9750258815152213 0.0482652109772803 0.9999999999998352 0.2564089333168017 5 O75116,Q13464 2 +Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.6827343683226406 1.9432192007766829 0.051989679122284 0.999999999999984 0.266481241525752 4 O15111 1 +Supression of hmgb1 mediated inflammation by thbd 0.679867962452124 1.928893250345376 0.0537441159379668 0.9999999999999948 0.266481241525752 4 O15111 1 +Angiogenesis 0.667164179104483 1.8884085490969644 0.0589711245278756 0.9999999999999998 0.2758089751636879 3 P19174,P28482 2 +Osteoclast signaling 0.660698299015216 1.8800128058668195 0.060106332668544 1.0 0.2772346351766178 2 O75348 1 +Cancer immunotherapy by pd1 blockade 0.6592166107148232 1.84849313742441 0.0645310362357367 1.0 0.2930989813760562 3 Q06124 1 +Mirna regulation of p53 pathway in prostate cancer 0.671511334770581 1.843158240716411 0.065305909950188 1.0 0.294371336517893 6 O96017,Q13315,P42574 3 +Photodynamic therapyinduced nfkb survival signaling 0.6516041382544381 1.8101365333271904 0.0702746167713681 1.0 0.3074755769513732 3 O15111 1 +Angiotensin ii receptor type 1 pathway 0.6512134426890619 1.7847231499623204 0.0743062340102433 1.0 0.3203783277977885 4 Q06124,P28482 2 +Nad biosynthetic pathways 0.6500437333857636 1.7561942938495112 0.0790552386975624 1.0 0.3289361330423054 5 P43490,Q8IXJ6,P09874 3 +Methionine metabolism leading to sulfur amino acids and related disorders 0.6482531959612982 1.7471027311449228 0.0806195197435872 1.0 0.3331153767182946 5 Q9NZL9,Q99707,P32929 3 +Il2 signaling pathway 0.6658590667826316 1.7260894962460738 0.0843313132098484 1.0 0.3428377116901118 11 Q06124,P36507,P28482,P22681,P40763,P62753 6 +Disorders of folate metabolism and transport 0.655495267795078 1.724037455335916 0.0847010817116746 1.0 0.3428377116901118 8 P00374 1 +Mbdnf and probdnf regulation of gaba neurotransmission 0.6485601053559414 1.7072865802759989 0.0877687991772595 1.0 0.3461353665894096 7 Q13464,O94973,P19174,P40763,P61586 5 +Bdnftrkb signaling 0.6499662713557923 1.695755445957141 0.0899322033289014 1.0 0.3461353665894096 8 Q15382,P28482,P42345,Q15418,Q15334 5 +Transsulfuration pathway 0.6498263504946059 1.6950390764998935 0.0900680081595615 1.0 0.3461353665894096 8 P26358 1 +Phosphoinositides metabolism 0.6532201992433205 1.694503130444726 0.090169717346821 1.0 0.3461353665894096 9 O00443,Q13614,Q01968,Q99570,O95248,Q8TBX8,Q9Y217 7 +Tp53 network 0.6271617182430149 1.6862093677506182 0.0917554802140458 1.0 0.3476507767205719 3 P42771 1 +Follicle stimulating hormone fsh signaling pathway 0.6442722684066535 1.6853745415854895 0.091916332258084 1.0 0.3476507767205719 7 P62753,P28482,P17612,P42345 4 +Ddx1 as a regulatory component of the drosha microprocessor 0.6353873438295162 1.6816079336269034 0.0926448911685045 1.0 0.3476507767205719 5 Q13315 1 +Map3k1 role in promoting and blocking gonadal determination 0.6345409397460975 1.6772893038113 0.0934859231517504 1.0 0.3476507767205719 5 Q13464,P49841,P28482 3 +Homologous recombination 0.6480366791454981 1.6678898915487177 0.0953375866909367 1.0 0.3523345595099836 9 P28340,Q13315,P49005 3 +Interleukin11 signaling pathway 0.6641416585938457 1.6599286591660607 0.0969288052140935 1.0 0.3551163739393719 15 Q06124,P36507,O75925,P28482,Q15257,P40763,P62753,O15111 8 +Osteopontin signaling 0.6307957159900741 1.6581659201532912 0.0972839814321304 1.0 0.3551163739393719 5 O15111 1 +Nanoparticle triggered regulated necrosis 0.6208955223880658 1.654263631583362 0.0980739589875669 1.0 0.3558171073024533 3 Q14790,P09874 2 +Il5 signaling pathway 0.646130713981367 1.608561531526487 0.1077122514855997 1.0 0.3819752848467359 12 Q06124,P36507,P49841,P28482,P40763,P62753 6 +Hijack of ubiquitination by sarscov2 0.6209763992483035 1.607923907166241 0.107851845133196 1.0 0.3819752848467359 5 Q8TBC4,Q13564,Q15369 3 +Ras and bradykinin pathways in covid19 0.6142831480054812 1.5966171282641712 0.1103510785173975 1.0 0.3865193732519778 4 Q13464,P28482 2 +Gpr143 in melanocytes and retinal pigment epithelium cells 0.6095470351480068 1.5962449894932782 0.1104341066434222 1.0 0.3865193732519778 3 P49407 1 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.6075798302806581 1.58616774120129 0.1127012634068083 1.0 0.3921476709184266 3 P28482 1 +Complement system in neuronal development and plasticity 0.6434009495405572 1.5793337701926358 0.1142595198169038 1.0 0.3925265955486386 13 Q8NI35,Q15398,P42574,Q8TEW0,P49327,Q7KZI7,Q8NB49,Q14790 8 +Il7 signaling pathway 0.6167380934512694 1.5440190222731531 0.1225837244248215 1.0 0.4120752318235527 7 P36507,P40763,P28482 3 +Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.6086390142095087 1.5222751078401071 0.1279401624815517 1.0 0.4252759590867221 6 Q13315,P26358,P51532 3 +Regucalcin in proximal tubule epithelial kidney cells 0.6084219688786284 1.5011394047201654 0.1333195087561665 1.0 0.4358522401643904 7 P42574,P28482 2 +Sulfation biotransformation reaction 0.5890039171590562 1.4907549128812794 0.1360258531233267 1.0 0.442269850319013 3 O43252 1 +Il4 signaling pathway 0.6189854839410737 1.4835116190838895 0.1379385317230381 1.0 0.4460512303000418 11 Q06124,O15111,P28482,P22681 4 +Kisspeptinkisspeptin receptor system in the ovary 0.6043583220190692 1.48016162849647 0.1388301179303659 1.0 0.4465076765868526 7 P49407,P28482,P31751 3 +Aryl hydrocarbon receptor pathway wp2586 0.6068891725914127 1.4739459414776348 0.1404961467938903 1.0 0.4494365986148642 8 P28482,P21359 2 +Intraflagellar transport proteins binding to dynein 0.6115432551045316 1.4617914269093355 0.1437983741190591 1.0 0.4551065563874479 10 P63167,Q8NCM8,Q14204,O43237,P63172,Q9BW83,Q96FJ2 7 +Vegfavegfr2 signaling pathway 0.2500886596967632 1.45058393436497 0.1468957515478102 1.0 0.4624495882060692 184 Q9UM54,O75569,P17655,P49841,P36507,O00299,O75116,P61353,Q13085,Q08209,P40429,Q01968,P49327,Q4G0J3,Q15369,Q02543,O15371,P07814,Q14241,P20248,Q13045,Q8N3C0,P40763,P46777,Q9BY44,Q01844,P62280,Q9Y520,Q9Y678,Q06124,Q9HCE1,P42345,Q9H299,P55196,Q9NZB2,P62906,Q7Z478,Q00610,P62753,Q9Y613,P31689,Q96SB4,Q9UG63,Q16512,P09429,Q13464,Q04637,P28482,P18124,P60953,P22681,P35579,P61254,P46940,Q9NSD9 55 +G13 signaling pathway 0.6233330222994479 1.432945388402102 0.1518734447914917 1.0 0.4731136107378932 16 Q16512,Q13464,O75116,P60953,O60610,P46940,P61586,Q7L576,O00401 9 +Cell migration and invasion through p75ntr 0.5924434880569698 1.3991506419997752 0.161767814159113 1.0 0.4925417458318804 8 Q16512,P31751,Q8TEW0,P40763,P61586 5 +Apoe and mir146 in inflammation and atherosclerosis 0.5660996717397704 1.3975473253174784 0.1622490456857959 1.0 0.4925417458318804 2 Q00653 1 +Nocgmppkg mediated neuroprotection 0.5826559420566229 1.3679271956681975 0.1713348661088853 1.0 0.5108488213385717 7 Q15334,Q13555,Q99996 3 +15q133 copy number variation syndrome 0.5649572814954511 1.366717439084279 0.1717138895255703 1.0 0.5108488213385717 3 Q9BXW9 1 +Alpha 6 beta 4 signaling pathway 0.5847824447567687 1.3594434564782478 0.174006108517787 1.0 0.5133975075561331 8 Q06124,P28482,P42345 3 +Il3 signaling pathway 0.592715852430875 1.346734506449637 0.1780657546686281 1.0 0.5162011879096265 11 Q06124,P28482,P17612,P22681,P40763 5 +Wnt signaling 0.6063152007317937 1.3432341356813418 0.1791961716165031 1.0 0.5162011879096265 16 P49841,Q13555,P68400,O75116,Q08209,P19784,P67870,Q9HCK8 8 +Aryl hydrocarbon receptor pathway wp2873 0.5643400262460903 1.3393599388994806 0.180453524512945 1.0 0.5162011879096265 4 O00170 1 +G1 to s cell cycle control 0.6196012020245623 1.3272665439172902 0.1844205268117784 1.0 0.5207247471041435 25 Q07864,P35244,P42771,P14635,Q13315,Q00534,Q9UBD5 7 +Epo receptor signaling 0.5746931765984049 1.3266986453302554 0.1846083892743806 1.0 0.5207247471041435 7 P40763,P28482 2 +T cell receptor and costimulatory signaling 0.5654042675511233 1.3215375824007038 0.1863221798807064 1.0 0.5229325331557563 5 P49841,Q08209 2 +Glucocorticoid receptor pathway 0.570195751183372 1.3034104317579038 0.192434676981718 1.0 0.5316781550192896 7 Q15185,Q13616 2 +Nitric oxide metabolism in cystic fibrosis 0.5603480602863831 1.2953938315066074 0.1951844048895299 1.0 0.5316781550192896 5 Q99873,O60678 2 +Serotonin receptor 2 and elksrfgata4 signaling 0.5551378121471433 1.2917904938131564 0.1964297083244059 1.0 0.5316781550192896 4 P28482 1 +Serotonin receptor 467 and nr3c signaling 0.5551378121471433 1.2917904938131564 0.1964297083244059 1.0 0.5316781550192896 4 P28482 1 +Nucleotide metabolism 0.5882853091393162 1.2913368992288234 0.1965868808474684 1.0 0.5316781550192896 13 P00374,P22392,P00492,P23921,P19623,P28340,P20839,P11908 8 +Synaptic signaling pathways associated with autism spectrum disorder 0.5877761479902889 1.2886745600916911 0.1975112503095197 1.0 0.5317610585256302 13 Q15382,P49841,Q9Y478,P28482,P42345,P31751,P21359,Q15334 8 +Dna mismatch repair 0.6017550591288305 1.2830911083522825 0.1994601585536384 1.0 0.5345891636910579 19 P52701,Q07864,P35244,P35251,P28340,P49005 6 +Neovascularisation processes 0.5523454628393236 1.2773555472182307 0.2014767510988426 1.0 0.5353283391903039 4 P28482 1 +Nipbl role in dna damage cornelia de lange syndrome 0.5605809093844637 1.2740140855969413 0.2026584242823361 1.0 0.535918944213289 6 Q13535 1 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.5849076531468411 1.2585700200264067 0.2081856813748825 1.0 0.5414050350864482 14 P41567 1 +Hypertrophy model 0.5439535190985865 1.2581507274939678 0.208337250543749 1.0 0.5414050350864482 3 P20248 1 +Genes related to primary cilium development based on crispr 0.5806350308988883 1.2513498413370394 0.2108068686777757 1.0 0.5438004909164913 13 P36405,P63167,Q7Z392,Q3SYG4,Q8NCM8,Q9Y496,P63172,Q9BW83,Q6UVJ0 9 +Autophagy 0.5705208667253185 1.248546591550468 0.2118309571707635 1.0 0.5438004909164913 10 Q9NT62,P42345,O95352,Q99570,Q96B36 5 +Target of rapamycin tor signaling 0.5764692255114073 1.2454933883705923 0.2129504443420882 1.0 0.5438004909164913 12 Q15382,Q13907,P42345,P60953,P04035,P62942,Q96B36 7 +Il6 signaling pathway 0.5737137900405853 1.2152108954140464 0.2242856659561654 1.0 0.5607463031872462 13 Q06124,P36507,P40763,P28482 4 +Hepatocyte growth factor receptor signaling 0.5706782390466187 1.1993758088113016 0.2303818496885914 1.0 0.5735447722372883 13 Q06124,P36507,Q16512,P28482,Q14185,P40763 6 +Ethanol effects on histone modifications 0.5636276825455238 1.195330416348902 0.2319579604591242 1.0 0.5745485716020556 11 P00374 1 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.5563889000808557 1.193390912843927 0.2327163121951183 1.0 0.5745485716020556 9 P49841,Q9Y478,P42345,P49770,O00401,Q96B36,Q13418 7 +Onecarbon metabolism 0.5741930610715444 1.188016436594129 0.2348269341239057 1.0 0.5773637429905948 15 P00374,P26358 2 +Breast cancer pathway 0.5911360815602934 1.172885439763563 0.2408417491808145 1.0 0.587459037858402 25 P36507,P49841,P68400,P28482,P09874,P42345,P31751,P19784,Q13535,Q13315,Q00534,P67870 12 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.527043336375388 1.170807709725398 0.2416760781450166 1.0 0.587459037858402 3 P31751 1 +Osteoblast differentiation and related diseases 0.5505277238900046 1.1448645682593763 0.2522652633014535 1.0 0.605416092011844 10 O00443,P28482,P78527 3 +Egfr tyrosine kinase inhibitor resistance 0.5683814941929025 1.1437820824210594 0.2527140223499642 1.0 0.605416092011844 16 P36507,P49841,P28482,P42345,P31751,P21359,P19174,P40763,P62753,O60573 10 +Integrated cancer pathway 0.567576890881375 1.1395710410929625 0.2544650557871355 1.0 0.605416092011844 16 O96017,P52701,P42574,Q13535,Q13315 5 +Melanoma 0.5648856480384855 1.13935626169145 0.2545545909476834 1.0 0.605416092011844 15 Q16512,P36507,P28482,P31751,P42771,P21359,Q00534 7 +Heart development 0.5272561441481318 1.1245623360181936 0.2607745414861091 1.0 0.6112502828711315 5 Q06124,P28482 2 +Resistin as a regulator of inflammation 0.5389733829346472 1.1223267687935448 0.2617235285217214 1.0 0.6112502828711315 8 P28482,O15111 2 +Tgfbeta receptor signaling in skeletal dysplasias 0.526711624731142 1.1217602136113125 0.2619644069447706 1.0 0.6112502828711315 5 P62942 1 +Tgfbeta receptor signaling 0.526711624731142 1.1217602136113125 0.2619644069447706 1.0 0.6112502828711315 5 P62942 1 +Il17 signaling pathway 0.5317706579141672 1.104895257714289 0.2692049775452108 1.0 0.6208409365868233 7 P40763,P28482 2 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.5439806701216431 1.0935471154314789 0.2741536542648224 1.0 0.6258058276057048 11 P67870,P19784,P49841,Q9HCK8 4 +Lncrna in canonical wnt signaling and colorectal cancer 0.555938540193051 1.0927282223953234 0.274513144546368 1.0 0.6258058276057048 15 P49841,P19784,Q00534,P67870,Q9HCK8 5 +Reninangiotensinaldosterone system raas 0.5088270857272778 1.077028357366117 0.2814675972292171 1.0 0.6347832294135822 3 Q13555 1 +Metastatic brain tumor 0.5082824380678517 1.0742322953812988 0.2827185811673938 1.0 0.6347832294135822 3 Q00534 1 +Embryonic stem cell pluripotency pathways 0.5436745634557796 1.0591420229450317 0.289535104277177 1.0 0.6476443121989485 13 Q06124,P36507,P28482,P42345,P31751,P40763 6 +Nanomaterial induced apoptosis 0.5161077775356397 1.0448886776171786 0.2960744233400056 1.0 0.6548858062725033 6 P42574,P55212 2 +Acute viral myocarditis 0.5523925806349096 1.03455096560105 0.300878663640737 1.0 0.6630474254305131 18 P49841,P28482,Q04637,P09874,P42574,P55212,Q00653,P40763,Q13418 9 +Omega9 fatty acid synthesis 0.512684461612259 1.027386152430351 0.3042386693821086 1.0 0.667977890340792 6 O95864 1 +Physicochemical features and toxicityassociated pathways 0.5461503625239016 1.0020919759561575 0.3162991729383888 1.0 0.6919044408027256 18 Q16512,P49841,P28482,P61160,P22681,O75116,Q13153,P19174,P07737,P61586 10 +Thymic stromal lymphopoietin tslp signaling pathway 0.5345432503736851 0.9967269914916772 0.3188970444703956 1.0 0.6950320199995801 14 Q06124,P28482,P42345,P40763,P62753 5 +Tolllike receptor signaling related to myd88 0.5059535941703548 0.9930628182711406 0.3206793422652862 1.0 0.6963657249921363 6 Q00653,P28482,O15111 3 +Dna damage response 0.5588491056634334 0.986447732106286 0.3239134519638076 1.0 0.6983141651209973 27 O96017,P30307,O95067,P42574,P35251,P14635,Q13535,Q13315,Q00534,P78527 10 +Transsulfuration and onecarbon metabolism 0.5444452573932412 0.9813229573329596 0.3264335051425693 1.0 0.6983141651209973 19 P00374,P26358 2 +Rett syndrome causing genes 0.5311430401505455 0.9792736358630422 0.327444793392871 1.0 0.6983141651209973 14 P27695,Q14839,P42858,P51532,Q9Y4A5 5 +Fibrin complement receptor 3 signaling pathway 0.492269839235111 0.9686292194667256 0.3327302192023111 1.0 0.7070517158049112 4 O15111 1 +Glioblastoma signaling pathways 0.5466946071205132 0.9613099219080296 0.3363963606010156 1.0 0.7118629040527846 22 P36507,P52701,P28482,P22681,O00443,P31751,P42771,P21359,Q13315,Q00534 10 +Head and neck squamous cell carcinoma 0.5354353715664687 0.9593407275903952 0.3373871242737567 1.0 0.7118629040527846 17 Q15382,Q13618,P42345,Q00653,P31751,P42771,P62753,Q00534,P11802,P62942 10 +Mthfr deficiency 0.5019048599609732 0.952299355002414 0.340945184849148 1.0 0.7134904753663905 7 P35790,P26358 2 +Pdgf pathway 0.533963329492172 0.9517715746271748 0.3412128409964654 1.0 0.7134904753663905 17 Q06124,Q16512,P28482,P60953,P19174,P40763,P61586,O00401,O15111 9 +Nucleotide excision repair 0.5464294782804295 0.9507014695797842 0.3417559419822207 1.0 0.7134904753663905 23 Q07864,P35244,P35251,P28340,P18074,P49005 6 +Neuroinflammation 0.4967436361951812 0.9463207557527036 0.3439850100404966 1.0 0.7156331502590751 6 O15111 1 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.4946115244218638 0.9355415692677008 0.3495092709334644 1.0 0.7245923909596214 6 P19174,P28482 2 +Cohesin complex cornelia de lange syndrome 0.5266930236589353 0.9278394010143464 0.3534908823731832 1.0 0.7303023437918196 16 Q9NTI5,Q15257,Q29RF7,Q14674,Q7Z5K2 5 +Oncostatin m signaling pathway 0.5287713486176504 0.925148354239918 0.3548887436447414 1.0 0.7306532957391736 17 Q06124,P28482,P42345,P42574,P20248,P40763,P62753 7 +Alzheimers disease and mirna effects 0.3597543463224629 0.9121104906391588 0.36171055644121 1.0 0.7395800037199998 89 P36507,P17655,P49841,P68400,P28072,Q08209,P31751,P49327,Q00535,Q15008,O00487,P49721,Q9BUF5,P60900,P25787,P20618,Q13885,P67870,Q96IX5,Q13564,O14654,P04350,P42345,P42574,P07437,P14735,P19784,O43242,Q13200,P28066,P25789,O15111,P28482,P49720,Q99570,Q14790 36 +Oxidative damage response 0.4931250075864701 0.9079696083281305 0.3638942788825261 1.0 0.7400999364268339 7 P42574,P60953 2 +Bladder cancer 0.4876874968459485 0.9006577229606376 0.3677703335391247 1.0 0.7400999364268339 6 P36507,P28482,P42771 3 +Retinoblastoma gene in cancer 0.5386622900822218 0.8955139623569497 0.3705124054064561 1.0 0.7400999364268339 47 P00374,P52701,P09429,Q07864,P23921,P35244,Q13309,P14635,Q14527,P26358,Q00534,P78527 12 +Ciliopathies 0.5252778567977516 0.8946565703060423 0.3709707013348038 1.0 0.7400999364268339 18 P36405,P57076,Q8TD19,Q3SYG4,Q13432,Q93008,Q8NCM8,Q01968,Q99570,O43924,Q15555,Q86Y56,Q9BW83 13 +Alzheimers disease 0.3717808306182071 0.8921755379163095 0.3722988516482171 1.0 0.7400999364268339 87 P36507,P17655,P49841,P68400,P28072,Q08209,P31751,P49327,Q00535,Q15008,O00487,P49721,Q9BUF5,P60900,P25787,P20618,Q13885,P67870,Q13564,O14654,P04350,P42345,P42574,P07437,P14735,P19784,O43242,Q13200,P28066,P25789,O15111,P28482,P49720,Q99570,Q14790 35 +Mirna regulation of dna damage response 0.5412628348241912 0.8873444095970769 0.3748935028246201 1.0 0.7400999364268339 28 O96017,P30307,O95067,P42574,P35251,P14635,Q13535,Q13315,Q00534,P78527 10 +Apoptosis modulation by hsp70 0.4887800378812055 0.8861489379981393 0.3755372749576948 1.0 0.7400999364268339 7 P42574,P55212 2 +Methionine de novo and salvage pathway 0.4963106604998741 0.8860106134378679 0.3756118080167407 1.0 0.7400999364268339 9 Q13126 1 +Glycogen synthesis and degradation 0.5234045832492801 0.885112386830319 0.3760960193441232 1.0 0.7400999364268339 18 P49841,P06737,Q15257,P46976,P63151,P35573,Q14738,P11216,P13807 9 +Mirnas involved in dna damage response 0.4747971561887646 0.8804485814531049 0.3786163484112617 1.0 0.7400999364268339 4 Q00534 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.479111378658241 0.8795396141246482 0.379108763966643 1.0 0.7400999364268339 5 P42574,Q14790 2 +Microtubule cytoskeleton regulation 0.521511767408341 0.8754873356312294 0.3813087980542322 1.0 0.7400999364268339 18 Q16512,P49841,Q13464,P17612,P60953,Q7KZI7,P40763,Q7Z460,P46821,Q99661 10 +Endochondral ossification with skeletal dysplasias 0.4820046862108958 0.872179327426894 0.3831105553268317 1.0 0.7400999364268339 6 Q9Y496 1 +Endochondral ossification 0.4820046862108958 0.872179327426894 0.3831105553268317 1.0 0.7400999364268339 6 Q9Y496 1 +Dna repair pathways full network 0.5270470459693429 0.8677116846967132 0.3855521875740659 1.0 0.7424063158788649 51 P52701,P09429,P27695,Q07864,P29372,P09874,P35244,P20585,P18858,P35251,Q13535,P28340,Q13315,P18074,P78527,P49005 16 +Kit receptor signaling pathway 0.513175142223577 0.8592398902537212 0.3902081796739713 1.0 0.7465524275752216 16 Q06124,P36507,P28482,P22681,P46109,Q15418,P40763,P62753 8 +Dna replication 0.5367296322644143 0.858180689827501 0.3907926970693225 1.0 0.7465524275752216 29 Q07864,P35244,P35251,P28340,Q9UBD5,P49005 6 +Male infertility 0.5274365377858645 0.8523158514704438 0.3940388103965573 1.0 0.7483457724026249 23 P49917,P17096,P09874,Q99707,P49327,P35251,O75909,Q13315,P18074 9 +Camkk2 pathway 0.4997995242971318 0.8359085478063731 0.4032063533017493 1.0 0.757844374577696 13 Q13501,P28482,O00429,P42345 4 +Joubert syndrome 0.5157365845744843 0.8342631828998095 0.4041326938023228 1.0 0.757844374577696 19 Q9UM54,Q15382,Q3SYG4,P09874,Q13432,P42345,O43924,P61586,Q13315 9 +Nucleotide excision repair in xeroderma pigmentosum 0.532867687380288 0.8256616775577517 0.4089960369798906 1.0 0.7580687296225853 32 Q07864,P09874,P35244,P35251,P28340,Q86WJ1,P18074,P49005 8 +Serotonin and anxiety 0.4587321769696242 0.8234555940471332 0.4102489595604579 1.0 0.7580687296225853 3 Q06787 1 +Tcell activation sarscov2 0.5072411307964052 0.8161832959115962 0.4143953090969949 1.0 0.7633597799155171 17 P36507,Q15382,P49841,P28482,P42345,P42771,Q9UDY8,Q9H1B7,O15111 9 +Netrinunc5b signaling pathway 0.4894190550881508 0.7694059620116482 0.4416523503703544 1.0 0.8021601923054306 14 Q06124,P36507,P28482,P42574,Q15257,Q8TCG1,P62136 7 +Canonical nfkb pathway 0.4521945389825036 0.768484775663465 0.4421992320608088 1.0 0.8021601923054306 4 O15111 1 +Vitamin a and carotenoid metabolism 0.4500566332751096 0.758049406113232 0.448421406175028 1.0 0.8109748835080294 4 P29375 1 +Ovarian infertility 0.4444445324922772 0.7531874022775056 0.4513373084587457 1.0 0.8137748440392537 3 Q13315 1 +Integrinmediated cell adhesion 0.5102222767134265 0.7480787200754816 0.4544126767426877 1.0 0.8147926135629258 25 Q16512,P36507,P17655,Q13464,P28482,Q14185,O75116,P60953,P31751,Q14155 10 +Transcription cofactors ski and skil protein partners 0.4513492536711361 0.7425823377030997 0.4577345850679484 1.0 0.8147926135629258 5 P21359 1 +Nonsmall cell lung cancer 0.4923186081213039 0.7423430932478017 0.4578794887208857 1.0 0.8147926135629258 17 P36507,P28482,P42574,P31751,P42771,P11802,P40763,Q00534,Q14790 9 +Purine metabolism and related disorders 0.486531275686307 0.7409087290873706 0.4587487824261851 1.0 0.8147926135629258 15 P30566,P00492,P31153,P07741,P31939,P51580,Q06203,Q9BY32,P22102,P20839,O15067 11 +Regulation of actin cytoskeleton 0.5169235683053442 0.7347352325627049 0.4625007585263014 1.0 0.8190117598903255 39 P36507,Q14185,O75116,Q8TBX8,Q9Y2A7,P35241,O60610,Q96F07,Q8WUW1,O00443,Q9UQB8,Q14155,Q16512,P35580,Q13464,P28482,P60953,P46940,Q99570 19 +Wnt signaling pathway 0.4776688495101012 0.7271058434836368 0.4671611193499894 1.0 0.8248096914339575 13 Q00534,P49841,P28482,P42345 4 +Il9 signaling pathway 0.4576161349544724 0.7140196232734916 0.4752150453515043 1.0 0.8358292311856325 8 P40763,P28482 2 +Srebf and mir33 in cholesterol and lipid homeostasis 0.4507317665820408 0.6995239334364948 0.484224661292739 1.0 0.8369816120118612 7 P49327,P04035 2 +Thyroid hormones production and peripheral downstream signaling effects 0.4821843096468124 0.6931696974898285 0.4882030623962574 1.0 0.8369816120118612 17 Q15382,P49841,P28482,P17612,P42345,P62753,O60343,Q7LBC6,Q9UNY4 9 +Translation inhibitors in chronically activated pdgfra cells 0.4916965827165568 0.6931500021927715 0.4882154210093674 1.0 0.8369816120118612 21 P36507,P68400,P17612,P42345,P28482,Q04637,Q15418,P31751,P62753,Q14240 10 +Purine metabolism 0.4568625342204718 0.6925905501246508 0.4885665423577947 1.0 0.8369816120118612 9 P00492,P07741,P31939 3 +Fluoropyrimidine activity 0.4704249149681913 0.6922759870194524 0.4887640271219737 1.0 0.8369816120118612 13 P00374,P18074,P23921 3 +Leptin signaling pathway 0.5058817479569824 0.6861883465067926 0.4925943454618453 1.0 0.8374103872851371 32 Q06124,P36507,P49841,Q13464,P28482,P42345,O75116,P60953,Q13085,Q15418,P40763,P62753,O00629,O15111 14 +Mesodermal commitment pathway 0.4957092316122387 0.6686685657418046 0.5037069237139682 1.0 0.8538621641305159 26 Q92908,Q9HCM4,P00492,O75925,Q9H6R7,Q9UPN3,P17612,Q13085,O75717,P42858,O95071,Q8N3C0,Q86XI2,Q13620,Q9Y2X9,Q8IWS0 16 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.4329310726437607 0.6546084087529861 0.5127199087948224 1.0 0.8642162768637942 5 P11802,Q15648 2 +Praderwilli and angelman syndrome 0.4518463452042739 0.6518489647623297 0.5144986106682192 1.0 0.8647646139762442 10 P42771,Q00534,P11802,Q7L576,Q99741 5 +Dna damage response only atm dependent 0.4742979078770701 0.6316582816719356 0.5276101940276485 1.0 0.8736465025700817 19 P09429,P49841,P28482,P60953,Q00653,O00443,P31751,P42771,Q99570,P61586,Q13315 11 +Gastrin signaling pathway 0.4918290019042277 0.6305131602113686 0.5283588952563512 1.0 0.8736465025700817 29 Q06124,Q16512,P49841,Q13464,P28482,P42345,P42574,P60953,P49407,P42771,P40763,P62753,O15111 13 +Ebsteinbarr virus lmp1 signaling 0.4384146349985998 0.6234364030779753 0.5329977822402348 1.0 0.8736465025700817 8 O15111 1 +P53 transcriptional gene network 0.4383788863070711 0.6060763452813477 0.5444640578876094 1.0 0.8899893253932076 9 P49327,Q9UPY5,Q9Y478 3 +Cytosolic dnasensing pathway 0.4594970421276588 0.586579135852825 0.5574863986503897 1.0 0.90382672260758 17 Q9NW08,Q9BUI4,O14802,O15111 4 +Glycerolipids and glycerophospholipids 0.4252471519080774 0.5807724020180407 0.561393857568036 1.0 0.9043393819820662 7 O96017 1 +Prolactin signaling pathway 0.4732379736937223 0.5775060961866104 0.5635976216575505 1.0 0.9043393819820662 24 Q06124,P36507,Q16512,P28482,P22681,P42345,P42574,P40763,P62753 9 +Micrornas in cardiomyocyte hypertrophy 0.4728749358118486 0.5758258761204479 0.5647328814487296 1.0 0.9043393819820662 24 P36507,P49841,Q13464,P28482,P42345,O75116,Q08209,P31751,Q13144,P40763,O15111 11 +Nrp1triggered signaling pathways in pancreatic cancer 0.4406145957711216 0.5687199934194666 0.5695461773449111 1.0 0.9043393819820662 12 P36507,P28482,O14646,P31751 4 +Neural crest cell migration during development 0.430098696652809 0.5684383147496498 0.5697373801115542 1.0 0.9043393819820662 9 Q16512,P31751,P40763,Q99570,P61586 5 +Biomarkers for pyrimidine metabolism disorders 0.4211707732880784 0.5623923718663913 0.5738487151608251 1.0 0.9043393819820662 7 P12277,P11172,P04818,P23921 4 +Sars coronavirus and innate immunity 0.4017910447761261 0.5528794851551507 0.5803459359214143 1.0 0.9110971817235924 3 Q7Z434,Q9UHD2 2 +Ranklrank signaling pathway 0.4536744919956566 0.5370888232963902 0.5912062607352913 1.0 0.9177632372712234 19 P28482,P22681,P42345,P60953,Q00653,P31751,Q13501,O15111 8 +Type i interferon induction and signaling during sarscov2 infection 0.4019110182143889 0.5331671591772099 0.5939178727311369 1.0 0.9177632372712234 4 P19525,Q7Z434,Q9UHD2 3 +Cell cycle 0.4589286193880575 0.5309587669445248 0.5954473526535027 1.0 0.9177632372712234 56 P49841,Q13616,P42771,Q13535,Q9UBD5,P33992,Q13309,P20248,Q00534,P78527,P30307,Q9UJX5,P14635,Q13315,P11802,O96017,O95067,O43913,Q14674,P53350 20 +Ketogenesis and ketolysis 0.4083798393999914 0.5232845273771944 0.6007762666755851 1.0 0.9177632372712234 6 O43772 1 +Mirnas involvement in the immune response in sepsis 0.407837442887221 0.5209099219512852 0.6024295232226371 1.0 0.9177632372712234 6 O43318,Q00653,Q16539,O15111 4 +Estrogen signaling pathway 0.4115851994518409 0.5199455077402293 0.6031015559210897 1.0 0.9177632372712234 7 P28482,O15111 2 +Small cell lung cancer 0.4239368373418983 0.4953136927244908 0.6203787069156845 1.0 0.9392502051267998 12 P42574,O15111,Q00534 3 +Interferon type i signaling pathways 0.4402147011230757 0.4891738473973638 0.6247186231342687 1.0 0.942280777195655 18 Q06124,O75925,P06730,P22681,P42345,P46109,Q53EL6,P40763,P62753,P63244,Q99873 11 +Agerage pathway 0.4432174951149727 0.4808168547002941 0.6306466701183355 1.0 0.9475625472737618 20 Q13464,P28482,P42574,P60953,O60610,P40763,P61586,O15111 8 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.4372715547122598 0.4765806665343658 0.6336607532048513 1.0 0.94842340159476 18 Q16512,P36507,P49841,Q9UHD1,P22681,Q13153,P19174,P11802,Q9UDY8,O15111 10 +Tcell receptor tcr signaling pathway 0.4444912022701041 0.4671139417689184 0.6404183599734625 1.0 0.9512612143959408 22 Q06124,P36507,Q16512,P28482,P22681,P60953,P49327,Q9UDY8,O15111 9 +Disruption of postsynaptic signaling by cnv 0.4028739111275743 0.4661584390543909 0.6411020957525584 1.0 0.9512612143959408 8 P28482,Q06787,Q13555 3 +B cell receptor signaling pathway 0.4466271106581465 0.4591215698597718 0.6461468679237075 1.0 0.9539885518972852 24 Q06124,P36507,P49841,P28482,P22681,P60953,Q15418,Q9UDY8,O15111 9 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.4256833971699718 0.4392255458048968 0.6604981166021573 1.0 0.9679713777790236 17 P49841,P28482,P42574,Q00653,P31751,O15111 6 +Cardiac hypertrophic response 0.4212058047301019 0.4209699915809402 0.673776994694701 1.0 0.9825914505964388 17 P36507,P49841,P28482,P42345,P31751,O15111 6 +Pi3kaktmtor vitd3 signaling 0.3832128541647684 0.4173900497078174 0.6763931317569676 1.0 0.9839948982772512 6 P42345 1 +Measles virus infection 0.440215558045228 0.4045337615551106 0.6858202562822737 1.0 0.9887530374422346 28 P68400,P42574,Q00653,P49327,P40763,P19784,Q00534,P11802,P67870,O15111 10 +Pathways of nucleic acid metabolism and innate immune sensing 0.3774743117910694 0.3945931546466554 0.6931431662448133 1.0 0.9924805789064212 6 Q5TBB1 1 +Folate metabolism 0.4153945046844823 0.3872340593683196 0.6985829375072858 1.0 0.994394372767548 18 P00374 1 +Pancreatic adenocarcinoma pathway 0.4266197570371182 0.3774608665122101 0.7058311412089346 1.0 0.9992273426922338 24 Q16512,P36507,P28482,P42345,P60953,P31751,P42771,P40763,Q00534,P11802,O15111 11 +Chromosomal and microsatellite instability in colorectal cancer 0.4097667532322118 0.3758662647204563 0.7070163214679503 1.0 0.9992273426922338 17 P52701,P49841,P28482,P42574,P31751,P20585,P61586 7 +Translation factors 0.4404878109500799 0.3694375492138549 0.7118016141767374 1.0 1.0 38 P41567,Q05639,O15371,P13639,Q04637,O75153,P63241,P49770,Q13144,O60841,Q14152,Q14240,P26641 13 +Neural crest cell migration in cancer 0.3851265399148855 0.3659663823499177 0.7143901610224686 1.0 1.0 10 Q16512,P40763,Q99570,P31751 4 +Nongenomic actions of 125 dihydroxyvitamin d3 0.3753025106206401 0.3427573791734025 0.731780992171218 1.0 1.0 9 Q13555,P28482 2 +Apoptosis modulation and signaling 0.3963087223491964 0.3258376353729763 0.7445472023769448 1.0 1.0 17 P55212,P42574,P42771,P49327,Q9UER7 5 +Nad metabolism sirtuins and aging 0.3458642099564148 0.3087088696324566 0.7575429961872762 1.0 1.0 4 P09874 1 +Glucuronidation 0.3517810495184389 0.2997021077774708 0.7644043907003033 1.0 1.0 6 O60701 1 +Brainderived neurotrophic factor bdnf signaling pathway 0.4215238383714454 0.299230467703509 0.7647642038074018 1.0 1.0 47 Q06124,P36507,P49841,P68400,P67809,P13639,P42345,P42574,Q96P70,P28482,P60953,Q00535,P40763,P62753,Q13501,O15111 16 +Adipogenesis 0.3818846814796447 0.2955318760460387 0.7675876055824562 1.0 1.0 15 P17096,P14174,P10589,P49327,O14654 5 +Parkinsons disease pathway 0.3590921133446895 0.2857965816630494 0.7750339264195958 1.0 1.0 9 P42574,P55212 2 +Dna irdamage and cellular response via atr 0.4161542925016767 0.276717323247989 0.7819971690751315 1.0 1.0 38 O60921,O96017,P30307,P09874,Q92547,P46063,Q13535,Q13315,P53350,P78527 10 +Pyrimidine metabolism 0.4164839849652645 0.2764897508312123 0.7821719306106092 1.0 1.0 39 Q07864,P23921,P15531,P17812,P04183,P27708,Q9NW08,P28340,O14802,Q9BUI4,P49005 11 +Chemokine signaling pathway 0.4073412747829922 0.276051118750475 0.7825088039257406 1.0 1.0 29 Q16512,P49841,Q13464,P28482,O75116,P60953,P49407,P31751,Q8TEW0,P40763,O00401,O15111 12 +Neurodegeneration with brain iron accumulation nbia subtypes pathway 0.3725461512033984 0.2745137118563199 0.7836898676745925 1.0 1.0 14 Q9NT62,Q15382,P42345,O95352,Q13085,Q99570,Q96B36 7 +Met in type 1 papillary renal cell carcinoma 0.3938799500674608 0.2743607670093654 0.7838073899773463 1.0 1.0 22 Q06124,Q16512,P28482,P22681,P60953,Q14241,P31751,P40763 8 +Dna irdouble strand breaks and cellular response via atm 0.4064632671651382 0.2730914870371097 0.7847828904617618 1.0 1.0 29 O96017,P30307,P42574,P42771,Q13535,Q13315,P78527 7 +Tnfalpha signaling pathway 0.4045652918751755 0.2667539417767752 0.789658618675404 1.0 1.0 29 O15111,P68400,P06737,Q13616,P42574,P28482,Q00653,Q969G6,P53350,Q14790,Q13200,Q6GQQ9 12 +Nanoparticlemediated activation of receptor signaling 0.345824703174577 0.2667420510903392 0.7896677744688443 1.0 1.0 7 P36507,Q9Y490,P28482 3 +Transcriptional activation by nrf2 in response to phytochemicals 0.3375982670365928 0.266239725636452 0.7900545900964067 1.0 1.0 5 Q9UPY5,Q13155,P48507 3 +Mirna regulation of prostate cancer signaling pathways 0.3554798186911893 0.2622321129610865 0.7931424968507657 1.0 1.0 10 P36507,P49841,P28482,P42345 4 +Erbb signaling pathway 0.3811657874089252 0.2565678304538489 0.7975124114248371 1.0 1.0 19 Q16512,P36507,P49841,Q13555,P28482,P22681,P42345,P31751 8 +Network map of sarscov2 signaling pathway 0.4059677625162773 0.2547971746140549 0.7988797576004183 1.0 1.0 33 Q9H269,O75925,O95067,P42574,Q6PKG0,P14635,P62753,Q14240 8 +Endoderm differentiation 0.4022145546703805 0.2543787216343878 0.7992029880897642 1.0 1.0 30 Q86VP6,Q9HCM4,P00492,Q92908,O14981,Q12830,O75925,P15531,Q13085,O95071,Q8N3C0,Q86XI2,Q13620,Q9Y2X9,Q8IWS0 15 +Ampactivated protein kinase ampk signaling 0.3745494705264602 0.2441151163495792 0.8071416654954477 1.0 1.0 18 P13639,P42345,Q13085,P31751,P20248,P49327,P14635,P04035,P13807 9 +Spinal cord injury 0.3817726966022101 0.2430383613154637 0.8079756801613955 1.0 1.0 21 P27695,P28482,P14174,O75116,P42574,P60953,Q08209,P11802,P62942 9 +Focal adhesion 0.402990607263335 0.2365492890447103 0.8130064651206037 1.0 1.0 36 Q16512,P17655,P49841,Q13464,P28482,Q14185,O75116,P46109,P60953,O60610,P31751,P62136,Q13418 13 +Copper homeostasis 0.3297039715756919 0.2173862093085898 0.8279073776179839 1.0 1.0 7 O75880 1 +Endometrial cancer 0.3420241615349932 0.2112720968113703 0.8326749550100485 1.0 1.0 11 P36507,P49841,P28482,P31751 4 +Apoptosis 0.3656790062336985 0.2101837492972406 0.8335242624613426 1.0 1.0 19 P55212,P42574,P42771,P49327,O15111 5 +Vitamin d in inflammatory diseases 0.3279878742792946 0.201947929953861 0.83995743124966 1.0 1.0 8 O60244,O15111 2 +Initiation of transcription and translation elongation at the hiv1 ltr 0.336128577547916 0.1950432464624226 0.8453590919215903 1.0 1.0 11 Q08209,Q9H3P2,P18615 3 +Pyrimidine metabolism and related diseases 0.3215280233682626 0.1945896158161341 0.8457142330412599 1.0 1.0 7 P04818,P27708,P23921 3 +Energy metabolism 0.3485825342748576 0.1862041390292166 0.8522846782481364 1.0 1.0 16 Q15648,P49841,Q13555,Q8WVM0,Q08209,Q99873,Q9BQG0 7 +Il1 signaling pathway 0.3509861240394262 0.1850232290926712 0.8532108159450398 1.0 1.0 17 Q06124,P36507,P28482,P19174,Q13501,O15111 6 +Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.3162858550750733 0.1807884296867735 0.856533645232743 1.0 1.0 7 P28482 1 +Atm signaling pathway 0.3482435180451296 0.1779886518127595 0.8587318879807786 1.0 1.0 17 O96017,P14635,Q13315 3 +Hostpathogen interaction of human coronaviruses interferon induction 0.3187406457234517 0.1684045688939717 0.8662650139807302 1.0 1.0 9 Q13546,Q9UHD2,Q16539,O15111 4 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.3104299197925593 0.1661344848631747 0.8680511162458349 1.0 1.0 7 O15111 1 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.3176920886469015 0.1574170948585498 0.8749161416688076 1.0 1.0 10 P28482,P42345 2 +Aerobic glycolysis 0.319876170244523 0.1544882587599913 0.8772247682359842 1.0 1.0 11 P04075,P14618,P04406,P00338,P08237,P06744 6 +Cardiac progenitor differentiation 0.2888266974152892 0.1535821297030551 0.8779392281814529 1.0 1.0 3 P49841 1 +Egfegfr signaling pathway 0.371329136356869 0.1398892601581197 0.8887474870008909 1.0 1.0 43 Q06124,P36507,O14965,Q16512,Q13464,Q9UBC2,O15357,P42345,P22681,P46109,P28482,Q15418,P60953,P40818,P19174,P46940,P40763,Q6DN90 18 +Mecp2 and associated rett syndrome 0.34204491003982 0.1339217692111261 0.8934644360069897 1.0 1.0 22 Q14353,P62753,P67809,P21359 4 +Pathogenic escherichia coli infection 0.3465129110451269 0.1339151038634626 0.8934697067096635 1.0 1.0 24 P04350,Q13464,Q9BUF5,O75116,Q13885,P60953,Q92974,O00401 8 +Il10 antiinflammatory signaling pathway 0.2882051318643938 0.1336067097784087 0.8937135781287431 1.0 1.0 5 P40763,P30043 2 +Cori cycle 0.3127806046094003 0.1317135911961575 0.895210834961448 1.0 1.0 12 P37837,P04075,P06744,P00558,P11413,P04406,P11166,Q01813,P00338,P19367,P18669 11 +Mapk cascade 0.2998610013072046 0.1263993677928157 0.8994158025677255 1.0 1.0 9 P28482 1 +Thyroid stimulating hormone tsh signaling pathway 0.3328731613892953 0.1202605081509285 0.9042767869395194 1.0 1.0 21 P27695,P28482,P42345,Q15418,P40763,P62753,Q9UNY4 7 +Atm signaling in development and disease 0.3424669295964995 0.1175346928339105 0.9064363536503022 1.0 1.0 26 O96017,P42345,Q15257,Q13535,Q13315,P78527 6 +Photodynamic therapyinduced ap1 survival signaling 0.3003769553659469 0.11401137056346 0.9092287798146992 1.0 1.0 11 P49327,P42771 2 +Physiological and pathological hypertrophy of the heart 0.2906734766011143 0.1089835995180582 0.9132154985336696 1.0 1.0 9 P40763,Q08209,P28482 3 +Onecarbon metabolism and related pathways 0.3062470778581349 0.1070471977871731 0.9147515364241768 1.0 1.0 14 P35790 1 +Insulin signaling 0.353882250499107 0.1027883938225317 0.9181309168590392 1.0 1.0 48 P36507,P49841,O15357,P31751,Q9Y496,O14654,Q06124,Q9H4M9,P42345,Q15418,O00443,P46976,P17858,P13807,Q15382,P28482,P22681,Q99570,P08237 19 +Mevalonate pathway 0.2758517848667081 0.1023860589833549 0.9184502488374652 1.0 1.0 6 P53602,P04035 2 +Regulatory circuits of the stat3 signaling pathway 0.2859950436443532 0.1008625442760418 0.9196595767672048 1.0 1.0 9 P28482,P42345 2 +Hepatitis c and hepatocellular carcinoma 0.2955423016084325 0.0996782004627676 0.9205998078443792 1.0 1.0 12 Q06124,P42574 2 +Amyotrophic lateral sclerosis als 0.2929688309810302 0.09547553021014 0.923937125522009 1.0 1.0 12 P42574,P36507,Q9UER7 3 +Lipid metabolism pathway 0.2958748423848206 0.0949404479693998 0.9243621287699172 1.0 1.0 13 P17612,P53396,Q13085,P31751,P49327 5 +Hostpathogen interaction of human coronaviruses mapk signaling 0.2848177246555895 0.0879893787432516 0.9298851179343632 1.0 1.0 11 P36507,P06730,Q15418,P28482 4 +Common pathways underlying drug addiction 0.2778146807304729 0.0878468735673418 0.9299983820240972 1.0 1.0 9 P36507,P28482,P17612 3 +Tolllike receptor signaling pathway 0.3024898665969635 0.0824978937345786 0.9342507931833206 1.0 1.0 18 P36507,P28482,P31751,Q14790,Q9UHD2,O15111 6 +Proteoglycan biosynthesis 0.2589605734766973 0.0821354889094566 0.9345389723840876 1.0 1.0 5 Q8TB61,Q8NCH0,Q8WVQ1,Q96L58 4 +Angiopoietinlike protein 8 regulatory pathway 0.334829285420688 0.0809109133421524 0.935512800831782 1.0 1.0 35 P36507,P49841,P28482,P22681,P42345,Q15418,O00443,P31751,P49327,Q99570,P13807,O14654 12 +Hepatitis b infection 0.3275693284003929 0.0805494307073904 0.9358002839000248 1.0 1.0 30 P28482,P42574,P31751,P49327,P40763,O15111 6 +Gaba receptor signaling 0.2565022421524751 0.0645419967938252 0.9485386681947664 1.0 1.0 8 P63010,O94973,P80404,Q96CW1,O95782,Q9NQX3,P49189 7 +Endoplasmic reticulum stress response in coronavirus infection 0.2424584911375451 0.0573723060075739 0.954248623258827 1.0 1.0 6 P62136 1 +Rac1pak1p38mmp2 pathway 0.2763229003730291 0.0521891650068289 0.9583779662412296 1.0 1.0 18 Q06124,Q16512,P28482,O15111 4 +Sterol regulatory elementbinding proteins srebp signaling 0.3009591249538453 0.0441890725070682 0.964753692422357 1.0 1.0 34 P53992,Q13907,P17612,Q15436,P42345,P55735,Q13085,P53396,P49327,Q16850,O95486,P04035,Q9HCL2,Q9Y6B6 14 +Modulators of tcr signaling and t cell activation 0.2545063244990366 0.0439670072758444 0.9649307028035314 1.0 1.0 14 Q9UDY8 1 +Sting pathway in kawasakilike disease and covid19 0.2254269640069599 0.0428020368593204 0.9658593403003076 1.0 1.0 6 O00221,O15111 2 +Interleukin1 il1 structural pathway 0.2461682844990984 0.0403408232793781 0.9678214079822928 1.0 1.0 13 P28482,O15111 2 +Pdgfrbeta pathway 0.2320574162679426 0.0399261811842693 0.9681519781742688 1.0 1.0 9 P19525,Q02750,P45985,P62993,P19174,P40763,P42224,P27361 8 +Circadian rhythm genes 0.3028669167339674 0.0374824650675088 0.9701003211708256 1.0 1.0 45 Q9NRV9,P49841,Q9Y5V3,Q13616,P43490,O75116,P62136,P11802,P49327,Q9BQG0,P29375,O14744,P78527,P04818,Q06210 15 +Clear cell renal cell carcinoma pathways 0.2913232947092005 0.0336809808075543 0.973131545484027 1.0 1.0 38 Q14012,P04075,P06744,P14618,Q15382,P42345,P04406,Q13085,P53396,Q01813,P49327,P09972,P40763,P48163,P08237,Q13501,P17858,Q96B36 18 +Glycosylation and related congenital defects 0.2203947368421041 0.0332903430718762 0.9734430546052836 1.0 1.0 9 Q9H553,Q13724,P34949,Q2TAA5,Q9BT22,O75352,Q9BV10,O75340 8 +Ras signaling 0.2833966161721209 0.0331901603128255 0.9735229447338876 1.0 1.0 33 Q06124,P36507,Q96KP1,Q16512,P28482,P17612,P60953,P55196,Q13153,P31751,P21359,P19174,P61586,O15111 14 +Exerciseinduced circadian regulation 0.2390734851162367 0.0326428214436932 0.9739594214373436 1.0 1.0 15 P31689,Q13907,Q9Y2A7,P25789 4 +Pi3kakt signaling pathway 0.2916252549934723 0.0319649220535469 0.974500024739952 1.0 1.0 41 Q16512,P36507,P49841,P28482,P42345,P13807,P31751,Q16513,P62753,Q00534,P11802,O60573,Q14738,P63151,O15111 15 +Fragile x syndrome 0.2941401865220024 0.03134062783597 0.9749978899818588 1.0 1.0 46 P36507,Q08209,P62136,P21359,P19174,P42771,O95782,Q7L576,P17612,P51452,P53985,Q96F07,Q06124,P42345,P50570,Q00610,Q15382,Q06787,P28482,Q04637,P46821,Q15334 22 +Ectoderm differentiation 0.2627070959537997 0.030789764895436 0.9754372029818068 1.0 1.0 25 Q9UPP1,P42356,Q5JSH3,Q12923,Q6W2J9 5 +Gastric cancer network 1 0.2141013263139501 0.0277286269053723 0.9778785915090376 1.0 1.0 11 Q96Q89,O14965 2 +Photodynamic therapyinduced hif1 survival signaling 0.2107751318451931 0.0266177703297382 0.9787645996075374 1.0 1.0 11 P17858,P53985 2 +Mapk signaling pathway 0.2784565026371894 0.023640223517717 0.9811395873798724 1.0 1.0 46 Q16512,P36507,P28482,P17612,P42574,P51452,P46109,P60953,Q99956,P31751,P21359,P49327,P49407,Q9UER7,O15111 15 +Sarscov2 innate immunity evasion and cellspecific immune response 0.2050594472856994 0.0232046470325548 0.9814870318107868 1.0 1.0 13 Q14790,Q6PKG0,O43747,Q14258 4 +Eukaryotic transcription initiation 0.2187286161076372 0.022490232332053 0.9820569035007214 1.0 1.0 18 Q9NW08 1 +Selenium micronutrient network 0.2038908939980531 0.0209619694953044 0.9832759929510368 1.0 1.0 16 Q16881,Q99707,Q00653,P32929,Q969G6,Q8NFF5 6 +Corticotropinreleasing hormone signaling pathway 0.2246636523948928 0.0205659516370849 0.9835919013758034 1.0 1.0 23 P42574,P28482,P49407 3 +Nucleotidebinding oligomerization domain nod pathway 0.1891869779114208 0.0204677078321304 0.9836702720945067 1.0 1.0 13 P98170,Q7L5N1,Q9Y2Z0,P63000,Q04206,Q9P0J0,Q14790,O15111 8 +Tgfbeta signaling pathway 0.2530595906724831 0.0202761941391392 0.9838230462079236 1.0 1.0 35 P36507,O75925,O95067,Q13616,Q7Z3T8,Q13464,P28482,P60953 8 +Nrf2 pathway 0.2167979204237394 0.0184742465595709 0.9852605223276044 1.0 1.0 25 P30043,P11413,Q16881,P28161,Q9BYN0,P48163,P48507,P21266,Q9UPY5,Q13501,P52209 11 +Wnt signaling pathway and pluripotency 0.1742265935022587 0.0180730052543158 0.9855806131203916 1.0 1.0 16 Q15257,P49841,P61586,P63151 4 +Focal adhesion pi3kaktmtorsignaling pathway 0.2409178374806678 0.0158799175350772 0.987330191468874 1.0 1.0 42 P36507,P49841,P28482,P42345,Q13085,O00443,P31751,Q99570,P62753,O60573,Q14738,P13807,O14654 13 +Epithelial to mesenchymal transition in colorectal cancer 0.1480248659535691 0.0156517935468406 0.9875121854568234 1.0 1.0 26 Q16512,P36507,P28482,P31751 4 +Proteasome degradation 0.2344617127105616 0.0154200109942343 0.9876970988595076 1.0 1.0 41 P22314,P49721,P28072,P60900,P25787,P20618,P28066,P49720,P61289,Q15008,O43242,Q13200,P25789,O75832 14 +Thermogenesis 0.180030597536988 0.0152435298462693 0.987837893893722 1.0 1.0 30 P17612,P42345,O43772,P51532,P62753,Q7LBC6 6 +Parkinubiquitin proteasomal system pathway 0.2130691588404128 0.0146255946549214 0.9883308798534892 1.0 1.0 38 P22314,P04350,Q9BUF5,Q13616,Q13885,P07437,O75832,Q15008,O43242,Q14790,O00487,Q0VDF9,Q13200,P62195 14 +Nuclear receptors metapathway 0.2103096044847647 0.011912811448256 0.9904951764831722 1.0 1.0 53 Q13616,O00170,Q16881,Q15257,P49327,Q9BYN0,P40763,Q15185,Q9UPY5,Q13501,Q9HCL2 11 +Malignant pleural mesothelioma 0.2018496616127562 0.0087959736192872 0.9929819189492212 1.0 1.0 76 Q16512,P36507,P09429,P49841,P68400,Q13616,P42345,P28482,Q04637,Q15418,P31751,P42771,P19784,P62753,Q13315,P11802,P67870,Q9HCK8 18 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..84e60494609710901afd7e43107253384d5b02ba --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD5", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSF2", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APMAP", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG7", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AURKA", "B3GALT6", "B3GAT3", "BAG2", "BAG3", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BBS9", "BCAS3", "BCAT2", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BLVRB", "BPTF", "BRCA1", "BRD4", "BRIX1", "BRK1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "C1QBP", "C21orf59", "CA8", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBR1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CEP170", "CERS1", "CERS2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLK3", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "CORO1A", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGLN1", "EHD1", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERI1", "ESD", "ESPL1", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GABPA", "GALNT1", "GAMT", "GAPDH", "GART", "GATA6", "GBA", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPRIN1", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H4", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKG", "ILF2", "ILK", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "ITPR2", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "MACF1", "MAD2L1", "MAGED1", "MALT1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MEPCE", "MFN2", "MGA", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MKLN1", "MMAB", "MOCS1", "MOCS2", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPST", "MRE11", "MRPL19", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NARS2", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NONO", "NOP2", "NPC1", "NPC2", "NR2F1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC5", "OSBPL3", "OTUD7B", "OXCT1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATJ", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PIAS1", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLXNA1", "PMPCA", "PMVK", "PNP", "PNPO", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPM1L", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP4", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SASS6", "SBF1", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SEC13", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SELENOF", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFN", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A25", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC3A2", "SLC5A6", "SLC7A11", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD5", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SPEN", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STX4", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAF6", "TALDO1", "TAP1", "TARBP2", "TARDBP", "TBC1D4", "TBCA", "TBK1", "TBL2", "TCF20", "TCP1", "TDP1", "TDP2", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMEM70", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPMT", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT2A", "TRRAP", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2J2", "UBE2L3", "UBE2V1", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UPF1", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WASL", "WDCP", "WDHD1", "WDR1", "WDR26", "WDR34", "WDR44", "WDR45", "WDR5", "WDR73", "WDR74", "WFS1", "WIPI2", "WNK1", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", 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"results/proteins/hek293t_core/opencell_localization/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..67df2e35e35608656be9cffc17e5177ff7bd901b --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +cytoplasmic 0.3396667600190629 5.371522445241423 7.807464789025192e-08 1.3272681851431186e-06 1.3272690141512824e-06 422 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180 +nucleoplasm 0.3057040360349478 4.053042690009763 5.0555772624027995e-05 0.0008591006219432 0.0004297240673042 380 Q9UPT9,O43592,O60701,Q13614,P51532,Q00535,Q9H7E9,P49721,P78362,Q9NR45,Q9HAV4,Q9Y5K8,Q7Z4Q2,Q5VYK3,Q7L5D6,P53396,Q14997,Q9NYV4,Q08945,Q0VDF9,Q969U7,Q96EK5,Q9H4L7,Q7KZI7,O14802,Q7Z2T5,O43242,P26641,P28066,O75832,P57076,Q15003,Q9NW08,P60953,Q8NC96,P49720,Q9BQC3,O95373,P49841,P68400,Q92973,P42771,P42356,Q9Y4A5,Q96D46,P61970,P25787,P20618,P12277,P55060,Q9Y5L0,Q01844,P78527,Q9H2G2,Q9H8V3,P55212,P42574,Q9UJX5,Q15418,Q9NZB2,Q15185,P19784,O43237,O00629,Q13315,O60244,P11802,P31689,Q13200,O96017,P63167,Q9Y4P1,P49761,Q7Z5K2,Q9NV88,O00401,O00410,Q2NL82,P28072,Q9Y237,Q8IY37,P84085,P54132,P50579,P61081,Q8TBX8,Q9UI26,Q96HR8,Q99661,P52701,Q9Y3I0,Q15554,P25440,O60610,O75348,P67870,P17096,Q96P70,Q13501,O15111,O60333,O60921,P28482,P53350,Q99816,Q13907,P09874,O15397,P31751,P49327,Q15008,Q4G0J3,Q9BUI4,O14980,P14174,P18858,Q96F86,Q16513,Q13555,P61289,Q8TEX9 121 +focal_adhesions 0.4559771443731525 0.7246797490409432 0.4686485215295755 0.999978546794811 1.0 7 Q16512,Q14155,Q13418 3 +nucleolus_gc 0.3729615671010612 0.6671511075259708 0.5046756177473051 0.9999934968314272 1.0 83 Q2NL82,Q9Y237,P09874,Q8IY37,O75607,P61353,P42696,P62861,P50579,Q9BYG3,Q4G0J3,Q96D46,Q9H7E9,P78362,O14980,O43709,P42766,P46087,P46777,Q5C9Z4,P62280,Q08945,P17096,P84098,P36578,P62906,Q7KZI7,Q7Z2T5,P26373 29 +big_aggregates 0.4853336662607908 0.572243162861578 0.5671572494705694 0.9999993429286698 1.0 38 Q9NT62,Q96EK5,P68400,P26196,Q9Y5L0,Q92973,Q14997,P19784,O00629,Q9Y6D5,O60333 11 +nucleolus_fc_dfc 0.2970916991057299 0.0684183662399354 0.945452601941829 1.0 1.0 20 Q8IXT5,Q01844 2 +centrosome 0.3205079547112048 0.0669801370530683 0.9465975160193584 1.0 1.0 32 Q14008,P17612,Q99661,Q14204,Q7Z460,O43237,P53350,Q5SW79,O60333 9 +nuclear_punctae 0.2547931750241673 0.04035862501712 0.967807215808438 1.0 1.0 82 O60921,P52701,P25440,P67870,Q9NW08,Q6P9B9,P19784,Q9NYV4,O14802,Q01844,Q13315,P53350,Q8IXT5,Q13501,Q4G0J3,Q96HR8 16 +cytoskeleton 0.2471024459463928 0.0186341890585752 0.985132928641696 1.0 1.0 36 P63167,Q8WWK9,Q14008,P35580,Q9BW19,Q9UJX5,Q15019,P60953,P35579,Q99661,Q7Z460,P14635,O00139,Q5SW79 14 +cell_contact 0.2125045944193519 0.0180024822881745 0.9856368731531138 1.0 1.0 25 P50570,Q96N67,P22059,Q9Y2A7,Q9UQB8 5 +membrane 0.1617260306359022 0.0077067375585788 0.9938509739569183 1.0 1.0 78 Q9UM54,O43795,P31751,P42356,Q9Y2A7,P22059,P53985,P67870,Q9H2G2,P50570,Q00610,Q96N67,Q7KZI7,Q16513,Q9UQB8,Q13464,P35579,P60953,Q8NC96,O00401 20 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5e22ee9dd95bd26ce91892370acaaf4efbc9a324 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1S1", "AKT2", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC4", "ANKRD17", "ANKRD28", "ANKRD46", "ANXA11", "AP2B1", "AP2S1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG7", "ATL2", "ATM", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1", "BUB1B", "BUD23", "BYSL", "C12orf57", 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"PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB3GAP2", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBBP4", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "RER1", "RHEB", "RHOA", "RHOC", "RHOG", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAR1A", "SAR1B", "SARS", "SBDS", "SC5D", "SCAMP2", "SCD", "SCFD1", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC2A1", "SLC35F2", "SLC5A6", "SLC9A3R1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX9", "SPTLC1", "SPTLC2", "SQSTM1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STIP1", "STK4", "STT3A", "STT3B", "STX12", "STX18", "STX5", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TARDBP", "TCF25", "TCOF1", "TDP1", "TERF2", "TFRC", "TJP1", "TJP2", "TMA16", "TMED10", "TMED2", "TMPO", "TMPO", "TNPO1", "TNPO3", "TOMM20", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM24", "TRIM28", "TRIM33", "TRMT1L", "TRRAP", "TSG101", "TSR1", "TTK", "TUBB4B", "TWISTNB", "U2AF2", 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"DDX6", "DHX37", "DIAPH1", "DNAJA1", "DNAJA2", "DNAJC13", "DNAJC2", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1LI2", "DYNLL1", "ECT2", "EDC3", "EEF1G", "EIF3G", "EWSR1", "FAM120A", "FASN", "FAU", "GAK", "GBF1", "GET4", "GSK3B", "GYG1", "GYS1", "HEATR3", "HMGA1", "HSPA14", "HUS1", "IDI1", "ILK", "INPPL1", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "KIAA0368", "KIF1B", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KPNA3", "KPNA4", "LARP7", "LIG1", "MAP2K2", "MAPK1", "MARK2", "MED14", "METAP2", "MIF", "MSH6", "MTMR2", "MTOR", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO6", "NAF1", "NANS", "NCAPH", "NCKAP1", "NECAP1", "NEK9", "NEMF", "NFKB2", "NIFK", "NMD3", "NOM1", "NOP2", "NPM3", "NUTF2", "OCRL", "OSBP", "OSBPL11", "PAK1", "PARP1", "PFN1", "PI4KA", "PIK3C2A", "PIN4", "PIP4K2C", "PKM", "PKN1", "PKN2", "PLK1", "POLR2B", "POLR3A", "POLR3B", "POLR3C", "PPP6R1", "PRKACA", "PRKDC", "PSMA1", "PSMA2", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", 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b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e9deb5a81ebba79a59d7c6ecb95fe9589cd7926aacf3ed2d084778913a9ffc0 +size 146117 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..133e75384132090ef582bf50efda7e495bba10e4 --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7151d134046f3d440c13e020560689f730684be8b7dd3a9cc39188be4862743e +size 87257 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2d10345934e2b704d807235287b657f0893d5f9a --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +ribosomal protein 50 117 4.898031301419731 9.680161723668024e-07 52.657766990291265 120.1504854368932 -1.1188580775071333 0.366830351444047 16.3572632501004 6.355310810063214 1.8172532741960228 0.3740231821116406 0.0445972448182811 3.858469044544781e-06 9.7034564627241e-08 3.1926097971386962e-21 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9e57892f232c202d7606945c20c98fd35fe03cfe --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 160, + "title": "Average number of proteins per term", + "value": 14.3 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7b09e7e5f0d976db048243f6b2d834d02ca0c353 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bd14b98e064c7d907aa9424faf42ecaa6a016df3 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,54 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +ribosomal protein 0.4678426109801181 4.898031301419731 9.680161723668024e-07 0.0001548706688429 0.0001548825875788 117 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,Q9HD33,P26373,P18124,P62266,P62277,P39023,P61254,P62899,P82675,Q9NP92,Q9Y3U8 50 +replication origin binding protein 0.8042859351375189 2.5327878416592715 0.0113159419806463 0.8381155877225328 0.0952921429949165 4 Q9UBD5 1 +primase 0.6887496269770224 2.0197702127280475 0.0434072282473301 0.9991752255739986 0.1984330434163662 2 P49642 1 +RNA helicase 0.7093206203581256 1.9195081438899413 0.0549200566313268 0.9998811586830184 0.225313052846469 13 O60231,Q14147,Q8IY37,Q7Z478,Q8IX18,Q92620,Q6P158,Q9H6S0 8 +kinase activator 0.6748873863914289 1.8411204462644497 0.0656039100233583 0.9999807264377216 0.2499196572318411 7 O75909,O95067,P14635 3 +DNA ligase 0.635631154879125 1.7536702666088684 0.0794870231718256 0.999998242940582 0.2705941214360022 2 P18858 1 +Rel homology transcription factor 0.6381482385221318 1.742052605203346 0.0814992397300926 0.999998761992661 0.2716641324336422 3 Q8IWI9 1 +carbohydrate kinase 0.6394897706697802 1.7025228750379746 0.088657394068075 0.9999996459473144 0.2781408441351374 5 P08237,P17858,Q01813 3 +pyrophosphatase 0.6268143251692575 1.6844400827100687 0.0920966499062925 0.999999806652314 0.2817104259762755 3 Q9UKK9 1 +deaminase 0.6208040493163816 1.6299959862486744 0.1031023452879384 0.9999999725297798 0.2952418018759736 4 Q01433 1 +RNA methyltransferase 0.6217068778517534 1.4661416855274767 0.1426096913161982 0.9999999999796496 0.3740582067310118 13 Q9UET6,Q96FX7,Q8WVM0,Q8IY81,Q7Z2T5,Q08J23,Q7Z4G4 7 +decarboxylase 0.5853728085490297 1.4247255508912071 0.1542365502381966 0.99999999999771 0.3968619159927018 5 P30046 1 +guanyl-nucleotide exchange factor 0.6094766083239733 1.41774790180356 0.1562643794221263 0.9999999999984404 0.3968619159927018 12 Q7Z3U7,Q9H8V3,Q14185,Q96N67,Q92538,Q9Y6D5,Q14155 7 +non-receptor serine/threonine protein kinase 0.558101734175743 1.394447248455071 0.1631825886616755 0.9999999999995822 0.4079564716541889 65 P36507,P49841,Q13523,O75116,P31751,Q00535,Q13535,Q9Y4A5,O14965,P78362,P17612,Q9NYV4,Q00534,P78527,P42345,Q7KZI7,Q16513,Q13315,P11802,Q96SB4,O15111,Q13418,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,P53350 30 +C2H2 zinc finger transcription factor 0.5753881223246375 1.3731494091857488 0.169705903487241 0.9999999999998804 0.4177376085839779 5 Q9Y2X9,Q96JP5 2 +DNA helicase 0.5937416951853891 1.352079204131477 0.17634997915007 0.999999999999967 0.4223492415578035 11 Q9H4L7,P18074,P46063,P51532 4 +protein phosphatase 0.5952923404850623 1.2380761049670956 0.2156878430241735 1.0 0.4930007840552538 20 Q06124,P30307,Q08209,Q99956,Q9ULE6,Q12923,Q9UNI6,Q14738,P63151,O00743 10 +translation factor 0.5555106656716301 1.227402799587758 0.2196712346956046 1.0 0.4950337683281232 7 Q05639,Q06787,Q9Y450 3 +tubulin 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.4960615715292565 7 P04350,Q13885,Q9BUF5 3 +phosphodiesterase 0.5406948988907376 1.1712740422427927 0.2414886418138913 1.0 0.5292901738386658 6 Q9BQ52,O43924,Q9NZC3 3 +cysteine protease 0.554286584855575 0.9513438896746068 0.3414298338500545 1.0 0.6432282543484107 29 Q70CQ2,Q9UPT9,Q9Y4P1,P40818,Q93008,Q96FW1,Q14674,Q01804,Q96RU2,Q9UDY8,Q6GQQ9 11 +GTPase-activating protein 0.5225662909505944 0.9507820821857372 0.3417150101225932 1.0 0.6432282543484107 13 P46940,Q8TC07,Q15042 3 +kinase 0.5299243334872685 0.8844494799792946 0.376453622717789 1.0 0.6844611322141618 21 P22392,O00764,P35790,P15531,Q8WVC6,Q9BRR6,Q13572,Q9NVE7,O00443,P42356,Q8TBX8,Q16822,Q9HA64 13 +methyltransferase 0.504643981440699 0.8032211924820084 0.4218468985104839 1.0 0.7484984128958588 17 O43709,Q9H2P9,Q86W50,Q86TU7,Q9BV86,Q6UXN9,Q14353 7 +ubiquitin-protein ligase 0.4581972469632159 0.7015225187302149 0.4829769863860429 1.0 0.8220884874656049 66 Q96EP0,Q9UBT2,Q13616,Q9Y263,O95352,O15344,Q92990,O95071,P61081,Q9UII4,Q15386,Q86VP6,P22314,Q5TAQ9,Q86UK7,Q8TBC4,O94822,Q13564,Q9NT62,Q5T4S7,Q7Z6Z7,Q13404,Q9ULT8,O75592,Q5T447,Q13620,Q13618,O75155,Q99816 29 +translation release factor 0.423416158358533 0.6523679248549263 0.5141638509831687 1.0 0.855796477189669 3 P62495 1 +DNA metabolism protein 0.5005936740085875 0.6487322929497156 0.5165114275375626 1.0 0.855796477189669 38 O60921,P49917,P52701,Q07864,P09874,Q92547,O43670,P20585,P35251,P38935,P28340,Q15477,Q8IWS0,P54277 14 +exoribonuclease 0.4437946951942598 0.583103805621188 0.5598234220039693 1.0 0.8957174752063508 12 Q9Y2L1,Q8IZH2,Q9GZR2 3 +non-motor microtubule binding protein 0.4640251720785219 0.5627976747134846 0.5735726638876526 1.0 0.9086299625943012 21 P78559,Q14008,Q8WWK9,Q3KQU3,Q96CW5,Q9BSJ2,Q9UH99,Q7Z460,P46821,Q66K74 10 +aldolase 0.4020931766417116 0.5542347047809628 0.579418230107895 1.0 0.9088913413457176 3 P09972 1 +actin binding motor protein 0.3496917612315495 0.292544078688098 0.7698706631610972 1.0 1.0 6 Q9UM54,O94832 2 +zinc finger transcription factor 0.3619713021139801 0.2834341894281237 0.776844023065373 1.0 1.0 10 Q9H1B7,Q9UPT8 2 +G-protein 0.3378554213802064 0.2670753341748149 0.7894111584826407 1.0 1.0 5 P84085,P18085 2 +aminoacyl-tRNA synthetase 0.4060453086230768 0.2550517921763129 0.7986830972635575 1.0 1.0 33 P47897,P49589,P26639,P07814,P41252,O43776,P23381,P54136,Q9NSD9,Q9P2J5,P26640 11 +kinase modulator 0.3240276821652462 0.2122024780684516 0.8319490735455535 1.0 1.0 6 P67870 1 +translation initiation factor 0.3964565215522458 0.2106367548619283 0.8331707294689763 1.0 1.0 47 Q9ULC4,P41567,O15371,P41214,Q04637,O75153,P42696,Q92905,P63241,P49770,Q13144,Q9BY44,O60841,Q14152,Q9UJA5 15 +cytoskeletal protein 0.3059456229459141 0.1645479725540272 0.8692997847352182 1.0 1.0 6 Q15019,Q9UHD8,Q16181,Q14141,Q9P0V9 5 +homeodomain transcription factor 0.2954618461071038 0.1591898612789978 0.8735192915313634 1.0 1.0 4 Q13330,O94776 2 +phosphatase modulator 0.3065078476531293 0.1567731757517434 0.8754236140547009 1.0 1.0 7 Q9UPN7,Q8TF05,Q96QC0 3 +translation elongation factor 0.2949526814732761 0.0934777176487366 0.925524050914882 1.0 1.0 13 Q8NE71,O00178,Q9NUQ8,Q9UG63 4 +microtubule or microtubule-binding cytoskeletal protein 0.2877314343118157 0.0873743621295886 0.9303739474833068 1.0 1.0 12 P63167,Q96EX3,O43237,P63172,O43264,Q96FJ2 6 +microtubule binding motor protein 0.3068549911864414 0.0776480780079528 0.9381079970796338 1.0 1.0 21 Q15058,Q9BW19,Q9Y496,Q14204,Q96Q89,O00139,Q99661,O60333 8 +protease 0.337141033847698 0.0752132917646482 0.940045009011901 1.0 1.0 43 P28072,Q9UNS2,Q9UQ80,P50579,Q9NQW7,P49721,P60900,P25787,P20618,P62195,P55212,P42574,P55036,P25786,O43242,Q13200,P28066,P25789,P49720,Q9H4L4,Q14790 21 +nucleotide kinase 0.2785378238828094 0.070496271303971 0.9437986682368458 1.0 1.0 13 P04183,Q14558,Q13126 3 +histone modifying enzyme 0.2640036434396947 0.0517492817898309 0.9587284686276238 1.0 1.0 14 P29375,O14929,Q9H9T3,Q7LBC6 4 +RNA processing factor 0.3099407003250171 0.0509206334790485 0.9593887636983256 1.0 1.0 35 P57081,Q86TB9,Q6P1R4,Q8IYB3,O60294,Q6P6C2,Q9UBP6 7 +general transcription factor 0.3034165440006842 0.0488799060822984 0.961015002341111 1.0 1.0 32 Q15648,Q9ULK4,Q9Y6J9,O95163,Q12789,O60244,Q15369 7 +DNA-directed RNA polymerase 0.2672849786365835 0.0446231752453211 0.964407669882244 1.0 1.0 18 O14802 1 +mRNA polyadenylation factor 0.2378938674785403 0.0392497333817016 0.9686912826555264 1.0 1.0 11 A5YKK6,Q9UIV1 2 +reductase 0.2741348008708795 0.0284861935840607 0.9772743794856796 1.0 1.0 33 P00374,Q9P2T1,O95881,P23921 4 +nucleotide phosphatase 0.178368688377647 0.0231606534001058 0.9815221242196724 1.0 1.0 6 Q8WVQ1,P49902,Q5TFE4,Q9H857,Q9BY32 5 +scaffold/adaptor protein 0.1995215056028119 0.0115676241479775 0.9907705771190198 1.0 1.0 88 Q9Y5V3,O15084,Q15398,Q96F07,Q5VYK3,P46109,Q8NHU6,Q9UBB6,P49407,Q08AM6,Q9Y5X3,Q8N3C0,Q9NZQ3,Q9UNF1,O60271,Q9UQB8,Q92616,Q5SW79 18 +transporter 0.2168536984031853 0.0109669445696696 0.991249819652045 1.0 1.0 61 O14980,O14617,Q9HAV4,Q00169,Q96P70,Q8TEX9,O15397,O43772,Q92973,Q9Y5L0,P53985,Q9UIA9,Q9UI26,O00629,Q9UPY5,Q99805,O95373 17 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..671dc47ccd32c2724458356efd6f5f839bfe21ce --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligand-gated ion channel", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD28", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOL2", "APRT", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGDIA", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD2B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BDH2", "BLM", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX4", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP170", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENOPH1", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAHD1", "FAHD2A", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXC1", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HUS1", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "ISCU", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MBNL1", "MCCC1", "MCCC2", "MCEE", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NENF", "NF1", "NFKB2", "NFKBIE", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPN1", "PACSIN2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM34", "RBM4", "RBM47", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNF31", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A11", "S100A13", "SACM1L", "SAE1", "SAMHD1", "SAP18", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", 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0000000000000000000000000000000000000000..c37f0462cb3a85e893a0dcb6fd453e475d25313b --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Ribosomal protein 44 102 4.913062533362075 8.966466293448634e-07 44.13834951456311 104.5509708737864 -0.839027584662447 0.4092064110759666 15.168720536445749 4.970282954685487 1.664286665300548 0.3711973750179467 0.0042479052183326 7.683561152661267e-08 3.6767482225918744e-08 8.727219181131377e-22 +Kinase 50 119 4.878047991177286 1.0714086000618297e-06 29.444174757281555 103.84466019417476 -0.2192751790196224 0.62201990995362 12.072165290634954 17.79740751359367 0.9191239718594064 0.3288870087456925 0.3656241892717851 0.2610760015746404 0.0799208204266812 0.0114887824884256 +Atypical group 3 5 2.7459873771451457 0.0060329084772601 2.128640776699029 5.014563106796117 0.0814264921313593 0.5488402806206053 1.4732089989046924 1.745947194287626 0.8980631823569926 0.2901692172933006 0.0786913117950012 0.1515272625734178 0.0075105395483816 0.0079931710216612 +Eraser 2 7 2.4625775946788377 0.0137942321111548 1.8398058252427183 6.466019417475728 0.2411394874142441 0.537437853747302 1.7813946650272157 0.955977961932508 0.9018127180572736 0.3034784444914997 1.0 1.0 0.4465871194719102 0.1093101132411038 +RNA binding protein 69 265 2.3994425568262203 0.0164200559128928 87.39805825242719 263.81067961165047 -0.7141181185949859 0.5274837744320973 28.928381537264386 11.410822767756809 1.087336744382709 0.3484948637163224 0.032578273190247 0.000228654000574 4.10289764561375e-06 8.926358682865732e-14 +Nucleic acid binding 74 352 2.35979370979324 0.0182850999145018 113.94417475728156 345.7718446601942 -0.9848012837682238 0.468469235111674 35.78691372865069 18.45162616811088 1.4009825801667193 0.3527437669119357 0.0083980537661916 0.0007336551499258 1.4189544094399104e-05 3.5942272498178055e-11 +RNA helicase 7 11 2.105808103146437 0.0352210246833448 5.072815533980583 10.135922330097088 -0.3017149304938925 0.5736443511135565 2.764992465614387 1.3780423971476052 0.7787590829020186 0.2946511376460325 1.0 0.0013262573806951 0.0021013452038761 0.0043704316922178 +Protein kinase 36 82 2.0443033194108806 0.0409235915253352 20.09223300970874 68.12135922330097 -0.1885407530168121 0.6382294404073665 8.905449289760881 14.39153709303092 0.8281308874650661 0.3147542738878373 0.2363084452452126 0.2464649134105994 0.233075463775791 0.1323904313449431 +Kinase activator 4 8 1.978113302755952 0.0479159261906003 1.9150485436893203 4.968446601941747 0.0842687586319997 0.5728672617674504 1.3564183088971749 1.411284106646468 0.8989426298905858 0.3105795599392044 0.1594721229818057 0.2941077913158182 0.2179356607727124 0.2554523730097116 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3c4f5622a3bc6548518e315d6ed51b3af0e6236d --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 2110, + "title": "Average number of proteins per term", + "value": 3.1516587677725116 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b63e95185f22245f5dfbb5268aa5760b44273edc --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0d0c7cdbe4da3435782392338213b697d02c65b2 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,84 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosomal protein 0.5118562862439007 4.913062533362075 8.966466293448634e-07 0.0018901366736845 0.0011303360730662 102 P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q8IXT5,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P78316,P47914,P62750,P84098,P62854,P60866,P62906,P61313,P62753,P50914,P62910,Q9HD33,P26373,P18124,P62266,P39023,P61254,P62899,P82675,Q9Y3U8 44 +Kinase 0.4654483163645739 4.878047991177286 1.0714086000618297e-06 0.0022581199596662 0.0011303360730662 119 O75569,P36507,P49841,P68400,Q13523,O75116,P04183,P31751,P42356,Q00535,Q13535,Q9HA64,P78362,O14965,P17612,P12277,P15531,Q9NYV4,Q00534,P67870,P78527,Q9H2G2,O00764,P42345,O00443,Q15418,Q9UJ70,Q7KZI7,P19784,Q16513,O14976,Q13315,P11802,P17858,Q96SB4,O15111,Q13418,O96017,Q16512,P22392,Q13555,Q13464,P35790,P28482,Q99986,P49761,Q99570,P53350,P08237,P11908 50 +SRPK family 0.9346463742166484 3.161974242300565 0.001567034246769 0.9634485939543644 0.0121859265259458 2 P78362 1 +Replication origin binding protein 0.9242041875392908 3.097257529439936 0.0019532010979945 0.9838411014062686 0.0127989264495917 3 Q9UBD5 1 +Lysine demethylase 0.8674234055431386 2.844206057836486 0.0044522244623066 0.9999185212594832 0.0169876918905371 3 Q7LBC6 1 +PKN family 0.8570575947478358 2.8177240904489955 0.0048365351369787 0.9999639227338528 0.0175368412395579 2 Q16513 1 +PIKK family 0.865034338608532 2.813763533198207 0.0048965232594 0.9999682316983552 0.0176379765537556 4 Q13535,P78527,Q13315 3 +Atypical group 0.8543365793934428 2.7459873771451457 0.0060329084772601 0.9999971494248768 0.0199520954341988 5 Q13535,P78527,Q13315 3 +ROCK subfamily 0.8173679498657005 2.6359669751594077 0.0083897896469236 0.99999998096781 0.0241506905252507 2 O75116 1 +CK2 family 0.8080597014925408 2.5712580615387624 0.0101329788671389 0.9999999995353084 0.0270999729965058 3 P67870,P19784 2 +CDK4 subfamily 0.783049835869877 2.475624796702391 0.0133003269962863 0.9999999999994624 0.0321094850825677 2 Q00534 1 +Eraser 0.8012393600428761 2.4625775946788377 0.0137942321111548 0.9999999999998131 0.0328137877728711 7 Q8IXJ6,Q7LBC6 2 +RNA binding protein 0.264831096825499 2.3994425568262203 0.0164200559128928 0.9999999999999992 0.036857785081068 265 P08708,P62314,P46782,P62847,O43592,Q07020,P61353,P46776,O75153,P40429,P62424,P62701,Q8IYB3,Q4G0J3,P62241,Q8IXT5,P57081,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,Q9UBB9,Q01844,P46778,P62280,P27635,P62917,P47914,P78316,P62750,Q86TB9,Q9BTE6,P84098,P62854,P60866,P62906,P61313,P62753,Q9UJA5,Q15020,P50914,P09012,P62910,Q9HD33,Q8IY67,Q06787,P26373,Q04637,P62266,P62277,P18124,P39023,Q6PKG0,P51003,P62899,P61254,P63241,P82675,Q14152,Q9Y3U8,Q9Y3Y2,Q9Y2V2,Q6P2Q9 69 +DMPK family 0.7701573427439177 2.3923843757027496 0.0167393014400443 0.9999999999999996 0.0373755831095169 3 O75116 1 +Nucleic acid binding 0.2530770075787462 2.35979370979324 0.0182850999145018 1.0 0.0394898268368464 352 P08708,P62314,Q07020,P62847,P46782,P61353,O43592,P46776,O43670,O75153,P20585,P40429,P62701,Q8IYB3,Q4G0J3,Q9UBD5,Q8IXT5,P62241,P42695,P57081,P52701,P15880,Q15021,Q8IWR0,P62081,P62269,P62841,P42766,P83731,Q02878,P46779,P62280,Q9UBB9,Q01844,P46778,P27635,P62917,P78316,P47914,Q8IWS0,P62750,P17096,Q86TB9,P84098,P62854,Q29RF7,P60866,P62906,P61313,P62753,Q92917,Q9UJA5,Q15020,P50914,P62910,Q9HD33,P09429,O43913,P26373,P62266,Q9NTI5,P18124,P39023,Q6PKG0,P61254,P62899,P51003,P63241,P82675,Q14152,Q9Y3U8,Q8IY67,Q9Y2V2,P54277 74 +Intracellular chloride channel (clic) family 0.7472396299612067 2.30513348003829 0.0211590989371492 1.0 0.0439426168871899 2 O00299 1 +SLC12 family of cation-coupled chloride transporters 0.7232794341488548 2.16617571011806 0.0302977625119433 1.0 0.0564897695109129 3 Q9Y666 1 +RNA helicase 0.7407010555408736 2.105808103146437 0.0352210246833448 1.0 0.062979967865981 11 Q14562,Q14147,Q8IY37,Q7Z478,Q8IX18,Q92620,Q6P158 7 +Protein kinase 0.5231419489424957 2.0443033194108806 0.0409235915253352 1.0 0.0701452299906233 82 P36507,P49841,P68400,Q13523,O75116,P31751,Q00535,Q13535,P78362,O14965,P17612,Q9NYV4,Q00534,P67870,P78527,Q9H2G2,P42345,Q15418,Q7KZI7,P19784,Q16513,O14976,Q13315,P11802,Q96SB4,O15111,Q13418,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q99570,P53350 36 +Protein arginine methyltransferase 0.6975433993432151 2.016940726316571 0.0437016993179739 1.0 0.0735918480135076 4 Q99873,O60678 2 +Kinase activator 0.705668718960708 1.978113302755952 0.0479159261906003 1.0 0.0788631858519241 8 O75909,O95067,O95163,P14635 4 +IKK family 0.6684571769620861 1.9188473445709633 0.055003656109724 1.0 0.0870106044354697 2 O15111 1 +BUB family 0.6627872276932245 1.8904813242438077 0.0586936160004678 1.0 0.0916537064758102 2 O43683 1 +Other small molecule kinase 0.6541324829744078 1.7769328898286163 0.0755792821977356 1.0 0.1108216021106478 5 O00764,P35790,Q16822 3 +DNA ligase 0.635631154879125 1.7536702666088684 0.0794870231718256 1.0 0.115111612143138 2 P18858 1 +Rel homology transcription factor 0.6381482385221318 1.742052605203346 0.0814992397300926 1.0 0.1169819019255071 3 Q8IWI9 1 +Pyrophosphatase 0.6268143251692575 1.6844400827100687 0.0920966499062925 1.0 0.1281820127323728 3 Q9UKK9 1 +C2H2 zinc finger transcription factor 0.6279975659215522 1.6667414981338091 0.0955658174335303 1.0 0.132312253795767 4 Q9Y2X9,Q96JP5 2 +Deaminase 0.6258045167824986 1.6555478978189793 0.0978134089219511 1.0 0.1348230276614452 4 Q01433 1 +AGC group 0.6489744308849925 1.6390266755651164 0.1012077042722683 1.0 0.1382189359317062 11 Q16512,Q13464,P17612,O75116,Q15418,P31751,Q16513 7 +CMGC group 0.6604181133280156 1.5854226676014225 0.1128703343607311 1.0 0.1504061071529357 20 P78362,P49841,P68400,Q13523,P28482,P49761,Q00535,P19784,Q9NYV4,Q00534,P67870,Q96SB4 12 +MLK family 0.591763652640993 1.5297641374889162 0.1260751214674598 1.0 0.162702450334153 2 Q13418 1 +Kinase modulator 0.6459584645708197 1.528724519626442 0.1263327511163183 1.0 0.162935271916523 18 Q96P16,O95067,O95163,P20248,O75909,P14635,Q92616,Q5VZL5 8 +TKL group 0.5919402985074691 1.5058653909585218 0.1321017326188038 1.0 0.1683180288802392 3 Q13546,Q13418 2 +Helicase 0.6405716094174349 1.4475385576352315 0.1477461455025457 1.0 0.1831635528850596 24 Q14562,Q14147,Q8IY37,P46063,Q7Z478,A3KN83,Q9H4L7,Q8IX18,Q92620,Q6P158,P33993 11 +Lipid kinase 0.5925213160751307 1.4391563732378727 0.1501062229001157 1.0 0.1854356734890189 6 O00443 1 +CDK family 0.5820298838497641 1.3451734434454736 0.1785692301222814 1.0 0.2116747615494459 8 Q00535,Q9NYV4,Q00534 3 +Tubulin 0.5536906486697772 1.2179901728783482 0.2232277071881654 1.0 0.2500055531672128 7 P04350,Q13885,Q9BUF5 3 +Cellular structure 0.2559350399904672 1.197196524305585 0.2312299642805197 1.0 0.2566518803955269 111 Q9UM54,O43795,P31146,Q9BSJ2,P57737,Q99661,Q15058,Q9UPN3,Q9BUF5,Q13885,P35241,Q9Y496,Q9UH99,Q9NZ32,P04350,O94832,P55196,Q96CW5,Q96Q89,O43237,P47755,O60333,P78559,P63167,Q14008,Q9BW19,Q7Z460,P46821,Q9BTW9,O00401,Q66K74 31 +Dehydratase 0.5232507119632828 1.151247716264498 0.2496303398581985 1.0 0.2716338406574706 3 P21399 1 +Other group 0.5628294932110096 1.128626314412127 0.2590555051920957 1.0 0.2784549750154468 15 Q8TD19,O14965,Q99640,Q99570,P53350,O14976,Q9UHD2,O43683,O15111 9 +Protein phosphatase 0.5379766249731934 1.045817304624295 0.2956453901115567 1.0 0.3106632336331598 12 Q14738,P30307,Q8TF05,P63151 4 +HDAC class I 0.4861235452103712 0.985417308985854 0.3244191309088722 1.0 0.3405593861779703 2 Q13547 1 +Methyltransferase 0.5325609627601194 0.9718729425756968 0.3311137620371238 1.0 0.3474142406257242 15 Q96FX7,O43709,P31939,Q9H2P9,Q9BV86,Q6UXN9,Q9UBP6 7 +Enzyme modulator 0.2428167747423276 0.9395561155037314 0.3474452954404616 1.0 0.3643685752382575 120 Q9UNS2,Q15436,Q9Y263,O15397,P21359,O75909,Q15369,Q9UI26,Q7L576,P98170,P55060,O95163,O60518,P20248,Q5TAQ9,Q5T3I0,P61586,Q96F07,Q5VZL5,Q9H4M9,Q96P16,Q9UBC2,Q96P70,Q15257,P50570,P49407,O00429,Q96N67,P14635,O43242,O60271,Q92616,Q13200,Q15382,O95067,Q15019,P60953,Q93100,Q9H223,P46940,Q96CX2,O95373,O00410 43 +Chloride channel family 0.4765741569680598 0.936892202781896 0.3488140104023292 1.0 0.3656222364376127 2 P51790 1 +SLC27 family of fatty acid transporters 0.472993136377194 0.9187749788035168 0.3582132824566346 1.0 0.3752879970126609 2 O14975 1 +DNA helicase 0.5073452016971998 0.8896378587864949 0.3736603708743597 1.0 0.3908891336365389 12 P49736,P25205,P46063,P13010,Q9H4L7,P33991,Q96RR1,P33993 8 +Reductase 0.5211288684413447 0.8861861254627755 0.3755172388920358 1.0 0.3926369544411276 17 P00374,O95881 2 +KRAB box transcription factor 0.466707736922146 0.8631775110321628 0.3880398764331776 1.0 0.4053287818188142 3 Q9Y2X9 1 +Ubiquitin-protein ligase 0.5062985138118914 0.798880522080945 0.4243596941515608 1.0 0.4430474788024707 18 O94822,Q7Z6Z7,Q99816 3 +Non-motor microtubule binding protein 0.5040249516541162 0.7756217560380414 0.43797235077023 1.0 0.4570334619808038 19 P78559,Q96CW5,Q9UH99,P46821,Q9BTW9,Q66K74 6 +Kinase inhibitor 0.4606381250806747 0.7665987481475566 0.4433201200088921 1.0 0.4623852957087307 6 Q5VZL5 1 +Writer 0.4613946958112314 0.7142672588020643 0.4750619338779778 1.0 0.4937835864445976 9 Q99873,O60678,P26358 3 +DNA-directed RNA polymerase 0.4351738394332548 0.516351282455894 0.6056090850155944 1.0 0.627312307011735 14 Q9NW08,O14802 2 +Non-protein kinase 0.4446304512155909 0.4973118745078421 0.6189691393150709 1.0 0.6402082764484311 19 O00764,P35790,O00443,P42356,P17858 5 +Phosphodiesterase 0.3829880557200147 0.4707939028237826 0.6377879190443845 1.0 0.659026694017459 3 O43924 1 +Cysteine protease 0.4517035784289083 0.4245735845872966 0.6711475528018145 1.0 0.6924798711060287 46 Q70CQ2,Q9UPT9,Q8TC07,Q9UDY8,P55212,P42574,P61247,P17812,Q9Y4P1,P27708,Q14674,Q01804,Q96RU2,Q96FW1,Q06210,Q6GQQ9 16 +Unclassified protein 0.4241588113085293 0.4220850377886734 0.6729629485877164 1.0 0.694013598005905 18 P22392,O75569,Q9Y3D8,P15531,P12277,Q9BRR6,Q9NVE7,Q9UJ70,Q01813,P08237,Q9HA64,P11908 12 +CAMK group 0.3845883477902782 0.3776377896997102 0.7056996877889634 1.0 0.7263543127974208 9 O96017,Q7KZI7,Q9Y478,Q13555 4 +SLC35 family of nucleotide sugar transporters 0.3533273649656813 0.3692676650895853 0.711928224564073 1.0 0.7320509521589639 2 Q8IXU6 1 +Microtubule binding motor protein 0.3919547353461159 0.3308753351371318 0.740738653306777 1.0 0.7598242870575107 15 Q15058,Q9BW19,Q96Q89,Q9Y496,O00139,Q99661,O60333 7 +Microtubule family cytoskeletal protein 0.4221315631123205 0.3154897519148331 0.7523898308634276 1.0 0.7714006526345152 51 Q9BSJ2,O00139,Q99661,Q15058,Q9BUF5,Q13885,Q9Y496,Q9UH99,P63172,Q15555,P04350,Q96CW5,Q96Q89,O43237,O60333,P78559,P63167,Q14008,Q9BW19,Q3KQU3,P46821,Q9BTW9,Q66K74 23 +Actin binding motor protein 0.3496917612315494 0.292544078688098 0.7698706631610972 1.0 0.7874101305234683 6 Q9UM54,O94832 2 +Cell adhesion 0.3272004876506892 0.2213463630933096 0.8248227525977074 1.0 0.8419816197296385 6 Q9Y5V3 1 +CAMKL family 0.3057647752964391 0.1742168272688079 0.8616950615146453 1.0 0.877922056878755 5 Q7KZI7 1 +Nucleotidyltransferase 0.3754629989666221 0.1693006167999481 0.8655601908493682 1.0 0.8814343642336713 32 Q9NW08,O60942,Q5TAX3,O14802 4 +Polymerase 0.3507775142848996 0.1479580752800974 0.882375855074162 1.0 0.898124965849726 23 Q9NW08,O14802,P49005 3 +Translation initiation factor 0.3426979608465446 0.1352956399207343 0.8923781322227857 1.0 0.906556504087664 22 O15371,Q86TB9,Q04637,O75153,P63241,Q14152,Q9UJA5 7 +Aminoacyl-tRNA synthetase 0.3286706294464414 0.127265333599311 0.8987303969419758 1.0 0.9125703260575404 18 P23381,Q9NSD9,P41252,O43776 4 +Receptor 0.3453311984532216 0.119384503841298 0.9049707376321932 1.0 0.918023200194196 27 Q9ULC4,O14980,P20645,P41214,Q9HAV4,Q6NTF9,Q08AM6,Q9UQB8 8 +Epigenetic regulator 0.3439221179053026 0.1132207075946904 0.9098555789393716 1.0 0.9220918691460492 28 P25440,Q9ULI0,P51532,Q8IXJ6,Q8NB78,O60678,P26358,O14744,Q7LBC6,Q99873 10 +Protein methyltransferase 0.2689106722592836 0.0801559794298431 0.9361132007825868 1.0 0.9468834389507468 8 Q99873,O60678 2 +Small GTPase 0.307750800294049 0.0645170366018466 0.9485585421253702 1.0 0.9585529328948904 26 Q15382,Q96P70,P50570,P60953,P55060,O15397,O00429,P61586,Q9UI26,O95373 10 +V-type ATPase 0.2571770334928207 0.0613610929832344 0.9510716372454748 1.0 0.9606324339817864 9 Q9Y5K8,Q9Y487,P21281,Q9UI12,O75348,P21283,Q93050,P61421 8 +Transcription cofactor 0.2594469119451631 0.0505126693983175 0.9597138535738504 1.0 0.9688977182013516 13 Q96T76,O00625,O60244,Q15370,Q9Y5B9 5 +mRNA polyadenylation factor 0.220495966537192 0.0394729400882391 0.968513327378665 1.0 0.976379895255128 6 Q12996,P51003,Q10570,Q16531,Q96GM8 5 +Ligase 0.2632223005615955 0.0327268488619262 0.9738924130597052 1.0 0.9809556984361864 77 Q9UBT2,Q13616,O95352,O43776,P22314,P07814,P41252,P18858,P23381,Q86UK7,Q8TBC4,O94822,Q13564,Q9NT62,Q7Z6Z7,P26639,P50747,P47897,P49589,P22681,Q9NSD9,Q13620,Q99816 23 +Phosphatase 0.2839781442032423 0.0326144083684017 0.9739820797269244 1.0 0.9809556984361864 34 P30307,Q08623,Q5TFE4,Q8TF05,P62136,Q13614,Q01968,O95248,Q9H0R4,Q70Z53,P33316,Q14738,P63151 13 +Translation factor 0.2321462577769281 0.0193701873707256 0.9845457929768732 1.0 0.9906493195904637 28 O15371,Q86TB9,Q04637,O75153,P63241,Q14152,Q9UJA5 7 +G-protein 0.1874411756725254 0.014305863189392 0.9885859619620572 1.0 0.9938272291091584 36 Q15382,Q96P70,P50570,P60953,P55060,O15397,O00429,Q5TAQ9,P61586,Q9UI26,O95373 11 +Nuclease 0.2131145797269002 0.014230434417066 0.988646139289158 1.0 0.9938272291091584 40 P48634,Q8NHU6,Q9Y2L1,Q9BY44,Q9UHB6,Q9Y520,Q9HAU5 7 +DNA binding protein 0.2296916745349075 0.0118369147275095 0.9905557290353768 1.0 0.9952726610784024 60 P17096,P52701,O43913,Q9NTI5,Q29RF7,P20585,Q9UBD5,Q8IWS0,P54277 9 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5adc45c640682f5270838c8853ace563300da437 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein sigma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit beta-1", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 2B", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "ATR subfamily", "AUR family", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 2, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Alpha-tocopherol transfer protein-like", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arsenite methyltransferase", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-arrestin-1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional coenzyme A synthase", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CASP8-associated protein 2", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CRK7 subfamily", "CSK family", "CTP synthase 1", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-3", "Caspase-6", "Caspase-7", "Caspase-8", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 2 tau variant", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1A", "Coronin-1B", "Coronin-1C", "Coronin-7", "Coup transcription factor 1", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cystine/glutamate transporter", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication complex GINS protein PSF1", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 4", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity mitogen-activated protein kinase kinase 3", "Dual specificity mitogen-activated protein kinase kinase 4", "Dual specificity mitogen-activated protein kinase kinase 6", "Dual specificity protein kinase clk3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dynein light chain Tctex-type 1", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZFP91", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enolase-phosphatase E1", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Esterase", "Esterase OVCA2", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Follistatin-related protein 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GA-binding protein alpha chain", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock factor protein 1", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol 1,4,5-trisphosphate receptor type 2", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Katanin p60 ATPase-containing subunit A1", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LIM domain-containing protein 1", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MAST family", "MAX gene-associated protein", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA epimerase, mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 5", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "Na+/K+-ATPases", "Nardilysin", "Neural Wiskott-Aldrich syndrome protein", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nf-kappa-b essential modulator", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor NF-kappa-B p100 subunit", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoplasmin-3", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Opioid growth factor receptor", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylase b kinase regulatory subunit beta", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable asparagine--tRNA ligase, mitochondrial", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Protein AATF", "Protein BUD31 homolog", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRA10AC1", "Protein FRG1", "Protein LSM14 homolog B", "Protein NDRG1", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein VAC14 homolog", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase c beta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase 1L", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab proteins geranylgeranyltransferase component A 2", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor expression-enhancing protein 6", "Receptor-interacting serine/threonine-protein kinase 1", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoC", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Riboflavin kinase", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC35 family of nucleotide sugar transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC61 Molybdate transporter family", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-10", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine-protein kinase atm", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase atr", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tbk1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-dependent multivitamin transporter", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 7", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptosomal-associated protein 23", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 6", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 4", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "Tyrosyl-DNA phosphodiesterase 1", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 J2", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit G 1", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuole membrane protein 1", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "ZZ-type zinc finger-containing protein 3", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger HIT domain-containing protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "AMPD2", "ANAPC1", "ANGEL1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOL2", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "B3GAT3", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CBL", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CEP170", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHM", "CHML", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTSA", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCPS", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENOPH1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXC1", "FOXRED1", "FRA10AC1", "FRG1", "FSCN1", "FSTL1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS1", "GIPC1", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKG", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS2", "MASTL", "MAT2A", "MBNL1", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "MED21", "METAP1", "METTL1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGA", "MGAT5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL19", "MRPL20", "MRPL21", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NARS2", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCEH1", "NCL", "NCOA5", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEK9", "NF1", "NFKB2", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPM3", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OGFR", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OVCA2", "OXA1L", "OXCT1", "OXSR1", "P3H1", "PACSIN2", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNGTT", "RNH1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A11", "S100A13", "SAE1", "SAP18", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SNAP23", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOD2", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDP1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE4", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM38B", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2L3", "UBE4A", "UBIAD1", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WASF2", "WASL", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR4", "WDR74", "WDR82", "WNK1", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFP91", "ZFR", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF598", "ZNF644", "ZNHIT2", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AARSD1", "ACO1", "ACTR10", "ADPGK", "AFDN", "AK6", "AKT2", "AMPD2", "ARRB1", "ATAD2B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATR", "AURKA", "BAIAP2", "BRD2", "BUB1", "BUD23", "CAD", "CAMK2G", "CAPZA2", "CARHSP1", "CARS", "CASP3", "CASP6", "CBL", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CDC25C", "CDC42", "CDK12", "CDK4", "CDK5", "CDK6", "CHEK2", "CHKA", "CHTOP", "CHUK", "CKAP5", "CKB", "CLASP1", "CLCN3", "CLIC1", "CLK3", "CLUH", "COPS3", "CORO1A", "CORO7", "CPSF1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF3", "CTPS1", "CUL1", "CUL4B", "CYFIP1", "CYFIP2", "DCAF8", "DDB1", "DHFR", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DIS3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPH5", "DUT", "DYNC1LI2", "DYNLL1", "DYNLT1", "EHD1", "EHD4", "EIF2A", "EIF2D", "EIF3A", "EIF3D", "EIF4G1", "EIF5A", "ELOB", "ELOC", "ELP1", "EPRS", "EPS15L1", "ESPL1", "EWSR1", "FARSB", "FMR1", "FN3KRP", "FRA10AC1", "GAK", "GCN1", "GFPT1", "GPATCH4", "GPKOW", "GSK3B", "HDAC1", "HDHD2", "HLCS", "HMGA1", "HMGB1", "HUWE1", "IARS", "ILK", "IPO11", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "KCTD12", "KDM1B", "KDM3B", "KIF14", "KIF1B", "KIF20B", "KIF2A", "KIF2C", "KIF3A", "KIFC1", "LARP1", "LARP7", "LIG1", "LIMA1", "LTN1", "M6PR", "MACF1", "MAGED1", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K2", "MAP7D1", "MAPK1", "MAPRE2", "MARK2", "MCM2", "MCM3", "MCM4", "MCM7", "MCTS1", "MED14", "METTL1", "MGA", "MMS19", "MRPL47", "MRPS5", "MSH3", "MSH6", "MTMR2", "MTOR", "MYO1B", "MYO1D", "MYO6", "NAE1", "NAGK", "NARS", "NCAPD2", "NCAPD3", "NEK9", "NF1", "NME1", "NME2", "NOP14", "NT5DC1", "NTMT1", "NUDT5", "OCRL", "ORC3", "ORC5", "OTUB1", "OTUD4", "OTUD7B", "PANK4", "PAPOLA", "PATL1", "PCK2", "PDE6D", "PDS5A", "PDS5B", "PDXK", "PFKL", "PFKM", "PFKP", "PHF6", "PHKB", "PI4KA", "PIK3C2A", "PIK3R4", "PIR", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLK1", "PMS1", "POLD2", "POLR3A", "POLR3B", "PPP1CA", "PPP2R2A", "PPP2R5D", "PPP4R1", "PRKAB1", "PRKACA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF4B", "PRPF8", "PRPS2", "PRRC2A", "PRRC2C", "PSMD2", "PSMD3", "PTPA", "PUDP", "QARS", "RANBP6", "RAVER1", "RBM12B", "RDX", "RECQL", "RHBDD2", "RHEB", "RHOA", "RIPK1", "RNGTT", "ROCK1", "ROCK2", "RPL10", "RPL10A", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL31", "RPL32", "RPL35", "RPL36", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPRD1A", "RPS11", "RPS13", "RPS15", "RPS17", "RPS18", "RPS2", "RPS20", "RPS23", "RPS24", "RPS26", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS7", "RPS8", "SART3", "SBF1", "SBNO1", "SEC23A", "SEPT2", "SIRT2", "SLC12A7", "SLC27A2", "SLC35F2", "SLK", "SMARCA4", "SMARCAD1", "SNRPA", "SNRPD1", "SPAG9", "SRPK1", "SRPK2", "SRRM1", "SUN2", "SUPT16H", "TARS", "TBC1D15", "TBCD", "TBK1", "TDRD7", "TFIP11", "TK1", "TOE1", "TRMT6", "TRMT61A", "TSG101", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TWNK", "TXNDC12", "UBA1", "UBA2", "UBA3", "UPF2", "USP22", "USP28", "USP34", "VAC14", "VRK1", "WARS", "WASL", "WDR4", "WDR82", "XIAP", "XPO1", "XPO5", "XPOT", "XRCC5", "ZC3H7A", "ZCCHC11", "ZFP91", "ZMYM4", "ZNF207", "ZNF281", "ZNF598"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5ebda3d70a1ac6744a80e742d2e3d1f2faaad420 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tchem", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7a25df5d0d28963b41be5a5958087c8757c56eb8 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15493b4d8a8eb0d2dbf910f3633f02e1f59ceaf5fcbbe4204be5a70480501da6 +size 131932 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e13f49ecf132a6550bfaa67dbe4a8b16ec242df6 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f4293e15b61e2e180117028917ff64716086a6a5317162599420df6ee7313bd4 +size 138955 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3379dd96a881cb63a6e89e73adf4ded92873356e --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8805c390a7e87f17301f9fe948e9562ac6210aabf8b7f22648306616fb342370 +size 73846 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd1ebfd47b9e5d959f2adf722e930f502d75b412 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..06e316659efc042092fa94575fde7e2cba7f55af --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 838.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..dfe5665eb9be78c0beac3a7ecb7260fdf102deb7 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9832fc23ecc6d25abef5d9c2db86fcb693356f5b --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tchem 0.2186809872411883 1.2989675822372226 0.1939550546286865 0.577878924854669 0.7758202185147463 342 O15357,P51532,Q00535,Q13535,Q12923,Q13126,P78362,P53396,P42858,P08243,P20248,P40763,Q9NYV4,P53985,Q13564,Q99873,O00443,Q7KZI7,O14976,P47897,Q05639,P27695,P35790,Q00796,P60953,Q9UIF9,Q86TI2,Q01433,P17655,P68400,Q13523,Q9Y263,P42356,Q9H4A4,Q9NQW7,Q9P2J5,Q9UPY5,P13639,P17612,P50336,P29375,P26640,P78527,Q9GZT9,Q9H2G2,P55212,P42574,Q15418,Q8IXJ6,P19784,P14635,O60678,Q13315,Q9UDY8,O14744,P31689,Q96SB4,Q13418,O96017,Q12830,Q9BW19,P49761,P00492,Q9UPP1,P43490,Q13085,Q08209,Q13526,P62136,P54132,P50579,Q8TBX8,Q16850,P25440,P63151,P30307,Q15257,O15111,P28482,P29372,P53350,P46821,Q9UIV1,Q13907,P04183,P30419,P31751,P49327,O14965,P06737,P07814,P14174,P51452,P27708,P41252,P18858,Q06210,Q06124,P26639,P50570,P50747,Q16513,Q16512,Q13555,P31939,P29144,P42785 107 +Tclin 0.2372421826208515 0.0557780097970191 0.95551865330564 0.9999960851808056 0.95551865330564 89 P00374,P49721,P04350,Q07864,P23921,O75116,P62942,P28340,P26358,Q00534,P04035,O00217 12 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..671114ce81c5d24c83b16bea694475415e2c416a --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANKRD46", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf174", "C1orf198", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "C5orf24", "C8orf33", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NEMP1", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", 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at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5c3b0443e3d78b86597cbebfa8f8afcb4072e2ba --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..133d53655481976f8cad7a9b3fa4ae1014ad53f5 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,59 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ubl conjugation pathway 0.4863335526470289 5.643056069538666 1.6705791124536905e-08 2.9068034553623313e-06 2.9068076558434214e-06 148 Q70CQ2,Q9UPT9,Q96EP0,Q13616,Q93008,O95352,O95071,Q15369,Q9UII4,Q9Y314,Q15386,Q9Y5V3,Q86VP6,Q96JP5,P49427,Q14999,Q01804,Q13309,Q96BN8,Q5TAQ9,O95260,O94822,Q6GQQ9,Q9Y3I1,Q9NT62,Q5T4S7,Q7Z6Z7,Q96RU2,Q9ULT8,Q9UDY8,Q96FW1,Q9NR09,Q14258,O75925,O60826,O75592,P22681,Q9Y4P1,P40818,Q14527,O75155 41 +DNA damage 0.3787817183096324 3.5731835238955596 0.0003526674080778 0.0595294577605615 0.0122728258011082 135 P09874,Q99504,Q92547,P35244,P20585,O95071,Q13535,P28340,Q96FZ2,Q9NVI1,Q9ULC4,P57081,P52701,Q68E01,Q14997,P18858,Q8N3C0,Q08945,P78527,P18074,P49917,Q96QE3,Q07864,Q7Z6Z7,Q9Y620,Q9H4L7,Q96RU2,Q13315,Q96FW1,P49005,O96017,O60921,P09429,P27695,P29372,Q7Z7L1,Q86WJ1,P54277 38 +DNA repair 0.3616190970626508 3.134867653450415 0.0017193165959632 0.2587509121059674 0.0222216327840419 117 P09874,Q99504,Q92547,P35244,P20585,O95071,Q13535,P28340,Q9NVI1,P52701,Q68E01,Q14997,P18858,Q8N3C0,Q08945,P78527,P18074,P49917,Q07864,Q7Z6Z7,Q9H4L7,Q96RU2,Q96FW1,P49005,O96017,P09429,P27695,P29372,Q86WJ1,P54277 30 +mRNA capping 0.9183100514342696 3.052785502224761 0.0022672793910296 0.3262893207783179 0.0222216327840419 4 O60942 1 +Mitosis 0.3532950074470415 3.0219680796890245 0.0025113702920793 0.3543695892806296 0.0222216327840419 125 O43670,Q93008,Q6P1K2,O75909,Q2NKX8,Q9P258,Q6NUK4,Q9Y5K6,Q99661,P42695,Q14203,Q9NRZ9,Q69YH5,O14965,Q15021,P50748,P20248,Q14204,P63172,Q08J23,Q99741,P30307,Q9UJX5,Q29RF7,Q00610,Q8IXJ6,Q96Q89,P14635,Q9NTJ3,Q9BT25,Q9BPX3,Q9NR09,P43034,O96017,Q14008,Q15003,O95067,Q9BW19,Q9NTI5,Q15019,Q96GX5,Q92974,Q9H6H4,Q9BTE3,Q99986,Q9H900,Q7Z460,Q7Z5K2,P53350,O00401,Q13618 51 +Cell cycle 0.2910173455880107 2.9156742918162153 0.0035492080606926 0.4613346274277126 0.0268505305461099 238 Q9UPT9,Q15398,O43670,Q6P1K2,O75909,Q00535,P42695,Q9ULC4,Q9NVI1,Q9NRZ9,P50748,P20248,Q00534,Q13564,O14976,Q9NR09,Q15003,Q92974,Q8TCY9,P68400,Q6NUK4,P33992,Q14203,Q69YH5,Q15021,Q14204,Q9H8V3,Q9UJX5,Q15418,Q8TEW0,Q8IXJ6,P19784,P14635,Q13315,P11802,Q9BPX3,P33993,O96017,Q9BW19,Q9NTI5,Q96GX5,Q99459,Q9H900,Q7Z5K2,O00401,Q13618,O00743,Q9UPP1,Q93008,Q13526,P62136,Q2NKX8,Q99661,P49427,Q15554,P61586,P63172,Q08J23,Q99741,Q8WWK9,P30307,Q29RF7,Q96Q89,Q9NTJ3,P43034,O95067,P28482,Q15019,Q9BTE3,Q99986,Q7Z4H7,Q8TAE8,Q7Z460,P53350,Q13620,Q99816,Q9P258,Q9Y5K6,O14965,P18858,P49917,Q00610,Q16513,Q9BT25,Q14008,P40818,P61289,Q9H6H4 88 +Cell division 0.308004211510409 2.50981987966019 0.0120792757487717 0.8793173870972174 0.0602782082958032 165 O43670,Q93008,P62136,Q6P1K2,O75909,Q00535,Q2NKX8,Q9P258,Q6NUK4,Q9Y5K6,Q99661,P42695,Q14203,Q9NRZ9,Q69YH5,O14965,Q15021,P50748,P20248,P18858,Q14204,P61586,Q00534,P63172,Q08J23,P49917,Q9H8V3,P30307,Q9UJX5,Q29RF7,Q00610,Q8TEW0,Q8IXJ6,Q96Q89,Q16513,P14635,Q9NTJ3,P11802,Q9BT25,Q9BPX3,Q9NR09,O96017,Q14008,Q15003,O95067,Q9BW19,Q9NTI5,Q96GX5,Q92974,Q9H6H4,Q9BTE3,Q99986,Q9H900,Q7Z460,Q7Z5K2,P53350,O00401,Q13618,Q99816 59 +Hearing 0.7579826917338053 2.3566215740675194 0.0184420298270833 0.960791884531059 0.0764026949979165 2 Q9UM54 1 +Glycogen biosynthesis 0.7441027172290197 2.2453787910336915 0.0247438257761647 0.9872163382358128 0.100126178722155 4 P46976,P31751,P35573 3 +Phagocytosis 0.7369650087906483 2.2106971249888128 0.0270568177638677 0.99154290180422 0.1069974157025677 4 Q14185 1 +Transcription termination 0.7166753788301559 2.1338720230325214 0.0328532581864129 0.997009988112314 0.1150360811157827 3 Q9UNY4 1 +DNA excision 0.7148137358963363 2.124746697639165 0.0336077546342399 0.997389654884962 0.1150360811157827 3 P28340 1 +Pyrimidine biosynthesis 0.7002107152088677 2.030166043960835 0.0423396641258122 0.9994619767399464 0.1315553849623452 4 P17812,P27708 2 +DNA condensation 0.6992410048693818 1.945845247102324 0.0516733316018922 0.9999021218631716 0.1467718137289513 8 Q15003,Q15021,Q9NTJ3,Q9BPX3,P42695 5 +GMP biosynthesis 0.677611940298511 1.9406725941942709 0.0522980025930746 0.9999127244696052 0.1467718137289513 3 P49915,P20839 2 +Purine salvage 0.6754713941062316 1.8846374309631708 0.0594788051186001 0.9999767654574606 0.1568077589490367 5 P00492,Q13126 2 +Protein biosynthesis 0.3733423739085447 1.8142835126448915 0.069634088555472 0.999996486342945 0.1706525550514385 96 P41567,O43776,Q13144,Q9P2J5,Q8TEQ6,Q9ULC4,O15371,P13639,P07814,P41252,P49770,Q9BY44,P23381,P54136,P26640,P26639,Q9BTE6,Q7Z478,O43432,Q14240,O60573,P26641,P47897,Q05639,O75821,P41214,Q04637,Q6PKG0,P63241,O60841,Q14152,Q9NSD9,Q9Y450 33 +Oogenesis 0.6432339319323571 1.7215861645065391 0.0851445112478161 0.9999998114898871 0.1975352660949335 5 Q9H6S0,Q15645,Q96RD7 3 +Transcription 0.2353711676300905 1.6828287674709117 0.0924082443400344 0.9999999529072184 0.2088186300670909 379 Q15648,Q9UPT9,P67809,P10589,P51532,Q6P1K2,O75909,P38935,Q12873,P26358,Q9H3P2,Q9BWH6,Q9ULC4,Q9NRZ9,Q9ULK4,Q14241,O95163,P40763,Q08945,Q9BQ70,Q92499,Q92908,Q9H9T3,P49407,O14802,P20290,Q9HCK8,P27695,Q96EK7,Q9NW08,Q96KM6,P35251,Q9UIF9,P85037,Q9Y3Y2,Q8IUF8,Q14527,P61457,P68400,Q99504,Q12789,Q15369,Q9Y4A5,Q92600,O00625,P18615,Q13045,Q01844,P29375,Q8IWS0,Q9HCE1,Q8IXJ6,P19784,O60244,O14744,Q15047,O96017,O75925,Q12830,P63167,P51858,O14646,Q9Y6J9,Q8WVM0,Q99459,Q9BUJ2,Q9H582,Q9Y2X0,Q9Y5B9,Q14684,Q7LBC6,O75155,Q9UPP1,A5YKK6,Q9P2D1,P25440,Q14839,Q8N3C0,P18074,P17096,O75182,P28482,Q6W2J9,Q9UIV1,P09874,Q3B7T1,Q4G0J3,Q9BUI4,Q9UER7,O43709,Q8NB78,Q16513,Q9UNY4,Q16512,P22392,Q8IWI9,Q8WUA4,Q9Y2X9 98 +Transcription regulation 0.2302562761181452 1.671767965108541 0.094570086101716 0.9999999689013208 0.2109640382269049 349 Q15648,Q9UPT9,P67809,P10589,P51532,Q6P1K2,O75909,P38935,Q12873,P26358,Q9H3P2,Q9ULC4,Q9NRZ9,Q9ULK4,Q14241,O95163,P40763,Q08945,Q9BQ70,Q92499,Q92908,Q9H9T3,P49407,P20290,Q9HCK8,P27695,Q96EK7,Q96KM6,P35251,Q9UIF9,P85037,Q9Y3Y2,Q8IUF8,P61457,P68400,Q99504,Q15369,Q9Y4A5,Q92600,O00625,P18615,Q13045,Q01844,P29375,Q8IWS0,Q9HCE1,Q8IXJ6,P19784,O60244,O14744,Q15047,O96017,O75925,Q12830,P63167,P51858,O14646,Q9Y6J9,Q8WVM0,Q99459,Q9BUJ2,Q9H582,Q9Y2X0,Q9Y5B9,Q14684,Q7LBC6,Q9UPP1,A5YKK6,Q9P2D1,P25440,Q14839,Q8N3C0,P18074,P17096,O75182,P28482,Q6W2J9,Q9UIV1,P09874,Q3B7T1,Q4G0J3,Q9UER7,O43709,Q8NB78,Q16513,Q9UNY4,Q16512,P22392,Q8IWI9,Q9Y2X9 90 +Glycogen metabolism 0.617532683550323 1.5105433284447642 0.1309048421483472 0.9999999999750128 0.2751294468857313 9 P49841,P06737,Q93100,P31751,P62136,P11216 6 +Virus entry into host cell 0.586167236447102 1.4761486778464177 0.1399039835938462 0.9999999999959152 0.2798079671876925 3 P63172 1 +Coenzyme A biosynthesis 0.5835820895522457 1.462830501200173 0.1435137647766531 0.999999999998035 0.2837658530811096 3 Q13057,Q9NVE7 2 +Viral penetration into host nucleus 0.5493882423157169 1.3111885728487325 0.1897940620581732 1.0 0.3513209233842782 2 O00505 1 +Cell shape 0.5610994920824554 1.2766960712472006 0.2017095690299211 1.0 0.3694470001179607 6 Q96AC1,P35580,P35579,Q7L576,P15311 5 +Purine biosynthesis 0.5645013158654049 1.2172876859543065 0.2234947778204041 1.0 0.4009081581520651 10 P31939,Q06203,P49915,P12268,P22102,P20839,O15067 7 +Cilium biogenesis/degradation 0.5916269026146025 1.2085384814634432 0.2268402032080985 1.0 0.40275709549193 21 Q9H4M9,O14965,Q3SYG4,Q9Y5K8,Q9P1Y5,Q01968,Q9Y496,Q16513,Q9Y5Y2,Q86Y56,Q13618 11 +Differentiation 0.3393521570909216 1.1209556190190728 0.2623067541371457 1.0 0.4564137521986336 94 P49841,A1X283,Q4G0J3,P78362,P15531,Q14997,Q96RD7,Q00534,Q96EK5,Q7Z6Z7,P61247,Q8NHU6,Q8TEW0,Q8IXJ6,Q7KZI7,Q96N67,Q13501,Q96SB4,Q13555,Q96EK7,P60953,Q92974,P85037,Q9Y2X9,Q6P6C2,Q9H6S0 26 +Protein transport 0.2179939409115584 0.9573930795982338 0.3383688901249806 1.0 0.5502447372125854 246 Q7Z3U7,Q3SYG4,Q9Y3E0,O95352,O15397,O43933,P53618,Q9UI26,O75165,Q9NVU7,Q9Y6D5,Q96D46,Q9UBF2,Q14746,O14980,Q9HAV4,P61970,Q9Y5L0,Q9UIA9,O95070,Q9Y678,Q9Y6B6,Q9H269,Q9NT62,O94832,P53621,Q96P70,O00203,Q8WUX9,P49407,Q5JVF3,Q5SRE5,O00629,O60826,O14617,Q9Y4P1,Q96JB2,P63241,Q8TAG9,Q92538,P60059,Q9UID3,Q8TEX9,Q2M389,Q99816 45 +Nucleotide metabolism 0.5135032680243627 0.9207432740437 0.3571844773841603 1.0 0.5751068746336658 12 Q96DE0,Q01433 2 +tRNA processing 0.5501532283366838 0.9148543466933236 0.3602680996268366 1.0 0.5751068746336658 38 Q2VPK5,Q96FX7,O15091,O60294,Q9UBP6,P57081,Q9Y3I0,Q9UET6,O75818,O95163,Q6P1R4,Q08J23,Q9BQ52,Q92499,Q9H974,Q9H9T3,Q99575,P78346,O95707,Q7Z2T5,Q9UJA5,Q7Z4G4 22 +Nucleotide biosynthesis 0.4803983259737813 0.8859876255592276 0.3756241954001649 1.0 0.5941691818148063 5 P04818,Q14558,P11908 3 +Antiviral defense 0.4978844338267963 0.6600883970553018 0.5091971041666814 1.0 0.7704373576087179 29 Q9NW08,Q9NUQ8,Q13309,Q7Z7L1,O14802,Q9BUI4,Q9UII4,Q92499,Q14258 9 +Glycolysis 0.4652909325432999 0.6259828424894619 0.5313261951970474 1.0 0.790177418498173 16 P04075,P06744,P14618,P04406,Q9BRR6,Q01813,P09972,P08237,P17858,P18669 10 +Gluconeogenesis 0.4087820382179072 0.5638377989827797 0.5728645247085964 1.0 0.837633842851225 4 P06744 1 +Calcium transport 0.4135581230525769 0.4956874015688337 0.6201149770745835 1.0 0.8917355868675829 9 Q96RD7 1 +Chromosome partition 0.4357373606190535 0.421873180141981 0.6731175870719395 1.0 0.9220522284257048 23 Q93008,Q14674,Q6P1K2,O76071,Q96SB4 5 +Immunity 0.3240113552452687 0.4075685669649553 0.6835904452121604 1.0 0.9220522284257048 86 O15357,Q9BUI4,Q9Y3Z3,Q9UII4,P14174,P17812,Q01804,Q13309,Q96BN8,P78527,Q92499,Q6GQQ9,Q8IXJ6,O14802,Q9UDY8,Q13501,Q96FW1,Q14258,P09429,Q9NW08,Q92974,Q7Z7L1 22 +Exocytosis 0.4056734618427798 0.3821641621602659 0.7023396024286752 1.0 0.9310041741231904 15 Q8TAG9,O00443 2 +Wnt signaling pathway 0.4225315184048333 0.3299703234771866 0.7414223858492821 1.0 0.9485845230718756 29 Q70CQ2,P49841,Q9UPN3,Q9UGU5,Q96BN8,Q7KZI7,P19784,P67870,Q9HCK8 9 +RNA-mediated gene silencing 0.4074588856235225 0.321210664184889 0.7480507511639038 1.0 0.9500790562227684 22 O75569,Q9HCE1,Q9UIV1,Q5TAX3,Q06787,Q9HAV4,A5YKK6 7 +Biological rhythms 0.3888406064393715 0.1923323729287079 0.8474818618140747 1.0 1.0 50 P49841,P68400,P43490,O75116,Q93008,O95352,Q13330,Q00535,Q9Y5V3,P29375,P78527,Q06210,Q7Z6Z7,P42345,Q05086,O00429,O14744,O75592,Q00653,Q9BQG0 20 +DNA replication 0.3815722327699429 0.1815285227056727 0.8559527471595572 1.0 1.0 54 P23921,P25205,P35244,P54132,P49643,P28340,Q9UBD5,Q9Y3Z3,Q7Z6E9,P33992,Q7L590,Q9UFC0,P18858,P39748,Q08945,Q99741,P49917,Q07864,P49916,P09884,P33991,P33993,P49642,P49005,P31350,O43913,Q9BTE3,P35251,Q9Y5B9 29 +DNA recombination 0.3639437761250805 0.1643282034553499 0.8694727803328095 1.0 1.0 26 P09429,P27695,P35244,P18858,P78527 5 +Endocytosis 0.3678815017549923 0.145199970802035 0.8845529889864772 1.0 1.0 34 Q9UM54,Q9UBC2,Q96T51,Q13432,P15531,P50570,O94973,O00443,Q8NC96,O00429,Q9Y5X3,Q9P2R3,Q9P0V3,Q9Y217 14 +Symport 0.2916223077076026 0.1245639213740146 0.9008687924475628 1.0 1.0 7 Q9Y666 1 +Spermatogenesis 0.3333236415238806 0.1082198302884772 0.9138213150398358 1.0 1.0 24 Q15019,P46379,Q8NHU6,Q14141,Q14997,Q15645,Q96SI9,Q4G0J3,Q08J23,Q6P6C2,Q9H6S0 11 +Autophagy 0.3406748184467105 0.0961702838702286 0.9233853314330208 1.0 1.0 32 O14681,Q9H269,Q9NT62,P09429,Q9Y4P1,O95352,Q8IXJ6,Q13501 8 +Translation regulation 0.3415775798542084 0.0813184277922182 0.9351887192635446 1.0 1.0 49 P06730,Q9UIV1,Q9UQ80,A5YKK6,P31751,P40429,Q8TEQ6,Q92600,P07814,Q9BY44,P27635,O43432,P61221,Q92616,O60573,P63244,Q06787,Q04637,Q6PKG0,Q9H2U1,Q9Y450 21 +Meiosis 0.2895228389864398 0.0765903042026141 0.9389494724219818 1.0 1.0 15 Q9UH99 1 +Innate immunity 0.294271513621782 0.0402979342597056 0.96785560066491 1.0 1.0 66 P09429,P14174,Q9NW08,Q92974,Q01804,Q13309,Q96BN8,Q8IXJ6,O14802,Q9BUI4,Q9UII4,P78527,Q92499,Q14258 14 +Growth regulation 0.2408308915161855 0.0335205801262838 0.9732594544852068 1.0 1.0 15 Q9ULC4 1 +Carbohydrate metabolism 0.2687343937022424 0.0326454581847407 0.973957318743027 1.0 1.0 26 P49841,O95394,P06737,P46020,O60701,Q93100,P31751,P62136,Q96C23,Q8NCH0,P11216 11 +Angiogenesis 0.1894642322657911 0.0210435905193767 0.9832108831582052 1.0 1.0 12 Q9BUP3,Q9H2J4,Q9H6U6,Q96BN8,Q969H8,Q12904,P23381,Q9BXJ9,Q13685,P35613,O75340 11 +Neurogenesis 0.2651278424528048 0.0190688529311792 0.9847861786707854 1.0 1.0 47 P49841,Q9Y263,P51532,Q99426,Q00535,Q7L576,P15531,P63172,Q96EK5,Q9H8V3,Q9H9T3,Q96N67,Q8IXJ6,Q14155,Q06787,Q13555,P60953,Q92974,Q9P265 19 +ER-Golgi transport 0.2574669797820419 0.0167145650659834 0.9866643275422028 1.0 1.0 50 O14579,Q9UBF2,P53992,Q7Z392,P53621,Q15436,P84085,O15027,P18085,P53618,O95486,Q9Y296,O95070,Q9Y678,Q13618,Q9Y6B6 16 +Apoptosis 0.150932956825603 0.0129429179013249 0.9896733339546068 1.0 1.0 130 O14681,Q14185,P31751,Q00535,Q9UER7,P42858,Q96F07,Q13564,P55212,P42574,Q16513,P19784,Q13501,Q9NR09,O60333,O96017,O75832,P28482,P61803,P61289,Q66K74 21 +Ribosome biogenesis 0.1595655558536758 0.0098159072289105 0.9921681649408548 1.0 1.0 64 Q2NL82,P78316,Q9NUL7,Q9H9L3,Q9NVU7,P78527,Q96HR8 7 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..facc7b9bb38e26e5089b5c5747d9415cbb43fdfa --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "Cytoplasmic inwards viral transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Microtubular inwards viral transport", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine metabolism", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFTPH", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOL2", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARRB1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATR", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG3", "BAG6", "BAHD1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP3", "CASP6", "CASP7", "CASP8", "CBL", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPV", "CERS1", "CERS2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAO1", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COG7", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS1L", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENOPH1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FRYL", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGPS1", "GHITM", "GINS1", "GINS3", "GINS4", "GLRX", "GMPR2", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXIM1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INPPL1", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KATNA1", "KCTD5", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MALT1", "MANF", "MAP1S", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METTL1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MKI67", "MKRN2", "MLEC", "MMGT1", "MMS19", "MOB4", "MOCS1", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MRE11", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCEH1", "NCKAP1", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFKB2", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUBP1", "NUBP2", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGFR", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OXSM", "PA2G4", "PAAF1", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMS1", "PMVK", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKAG1", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTK7", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RELA", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN3", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPP40", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCCAG3", "SDHA", "SDHB", "SDHD", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SON", "SPAG5", "SPATA5", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TADA3", "TAF6", "TAF6L", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBCB", "TBK1", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TERF2", "TERF2IP", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLE4", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM14C", "TMEM214", "TMEM38B", "TMF1", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TTPAL", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WDR12", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WRAP53", "WTAP", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZNF703", "ZPR1", "ZW10", "ZWILCH", "ZYX", "ZZZ3"], "leading_proteins": ["AAMP", "AARSD1", "ABCE1", "ABCF3", "ADPGK", "AGL", "AIMP1", "AKT2", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC4", "ANKFY1", "AP2A2", "AP3B1", "AP3D1", "APEX1", "ARF4", "ARF5", "ARFGEF2", "ARHGEF2", "ARHGEF7", "ARRB1", "ASCC3", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP6V1D", "ATR", "AURKA", "BAG6", "BAZ2A", "BBS9", "BCAS3", "BCOR", "BIRC6", "BLM", "BPTF", "BRD2", "BSG", "BTF3", "BUD23", "CAD", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CASP3", "CASP6", "CBL", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CDC25C", "CDC34", "CDC42", "CDC5L", "CDC6", "CDCA2", "CDK4", "CDK5", "CDK6", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP7", "CHST14", "CHTOP", "CIAO1", "CKAP2", "CKAP5", "CLASP1", "CLTC", "CNOT1", "CNOT7", "CNOT9", "COASY", "COG2", "COG3", "COPA", "COPB1", "COPE", "COPG1", "COPG2", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTPS1", "CTU2", "CUL1", "CUL3", "CUL4B", "CUL7", "CYFIP1", "CYFIP2", "DAD1", "DAXX", "DCAF8", "DCTN1", "DDX1", "DDX28", "DHX29", "DHX36", "DIP2B", "DLGAP5", "DNAAF5", "DNAJC13", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DUS1L", "DYNC1H1", "DYNLL1", "DYNLT1", "ECT2", "EDRF1", "EEF1A2", "EEF1G", "EEF2", "EHD1", "EI24", "EIF1", "EIF2A", "EIF2B2", "EIF2B5", "EIF2D", "EIF3A", "EIF3D", "EIF3G", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G3", "EIF5A", "EIF5B", "ELAC2", "ELOA", "ELOC", "ELP1", "ELP3", "EPRS", "EPS15L1", "ERCC2", "ERCC6L", "ESPL1", "EWSR1", "EXOC6", "EYA3", "EZR", "FAM120B", "FANCI", "FARSB", "FBXO7", "FEN1", "FERMT2", "FLII", "FMR1", "FOXK1", "FTSJ1", "GADD45GIP1", "GAK", "GALM", "GAPDH", "GART", "GATA6", "GBF1", "GCN1", "GEMIN5", "GFPT1", "GMPS", "GOLT1B", "GPI", "GSK3B", "GTF3C1", "GTF3C2", "GYG1", "HAUS6", "HAUS8", "HBS1L", "HDGF", "HECTD1", "HELLS", "HERC5", "HLTF", "HMCES", "HMGA1", "HMGB1", "HMGXB4", "HNRNPUL1", "HPRT1", "HTATIP2", "HTT", "HUS1", "HUWE1", "IARS", "IGHMBP2", "IMPDH1", "IMPDH2", "INPPL1", "INTS3", "IPO11", "IPO4", "IPO8", "IPO9", "ISG20L2", "KDM1B", "KDM3B", "KDM5A", "KIAA0391", "KIF1B", "KIF20B", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KNTC1", "KPNA3", "KPNA4", "LARP1", "LARP7", "LARS", "LCMT2", "LIG1", "LIG3", "LIG4", "LRWD1", "LTN1", "MACF1", "MAGED1", "MALT1", "MAP1S", "MAPK1", "MARK2", "MASTL", "MCM10", "MCM3", "MCM4", "MCM5", "MCM7", "MCMBP", "MCTS1", "MED1", "MED14", "MED16", "MED23", "METTL1", "MGA", "MIF", "MON2", "MOV10", "MPG", "MSH3", "MSH6", "MTA1", "MTAP", "MTMR6", "MTOR", "MYBBP1A", "MYCBP2", "MYDGF", "MYH10", "MYH9", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NARS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NECAP1", "NELFA", "NELFE", "NFKB2", "NMD3", "NME1", "NME2", "NOP14", "NOSIP", "NR2F1", "NSUN2", "NUBP2", "NUDT16", "NUP188", "NUTF2", "OCRL", "ORC3", "ORC5", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "PA2G4", "PAFAH1B1", "PANK4", "PANX1", "PARD3", "PARP1", "PCBD1", "PCID2", "PDCD6", "PDCL3", "PDS5A", "PDS5B", "PEX1", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGM3", "PHF6", "PHF8", "PHKA1", "PHKB", "PIAS1", "PIK3C2A", "PIN1", "PIR", "PKM", "PKN1", "PKN2", "PLAA", "PLK1", "PMF1", "PMS1", "POLA1", "POLD1", "POLD2", "POLE", "POLR3A", "POLR3B", "POLR3C", "POP1", "POP4", "PPAT", "PPP1CA", "PPP6C", "PRIM1", "PRIM2", "PRKDC", "PRKRA", "PRMT5", "PRPS2", "PRPSAP1", "PSMD10", "PSME3", "PSME4", "PYGB", "PYGL", "QARS", "QTRT2", "RACK1", "RAD54B", "RARS", "RBBP6", "RCC2", "REEP3", "REEP4", "RFC1", "RHOA", "RIOX2", "RNF31", "RNGTT", "ROCK2", "RPA3", "RPAP1", "RPL10", "RPL13A", "RPP30", "RPP40", "RPS3A", "RPS6KA1", "RRM1", "RRM2", "RRP1B", "RTCB", "RUFY1", "SAMHD1", "SAR1B", "SDAD1", "SEC16A", "SEC23A", "SEC24A", "SEC24C", "SEC61G", "SEPT2", "SEPT6", "SETDB1", "SH3BP4", "SH3PXD2B", "SIN3B", "SIRT2", "SKP2", "SLC12A7", "SLFN11", 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pval_50 pval_100 pval_250 pval_500 +Mental retardation 47 175 2.4239273770856857 0.015353675522185 43.33980582524272 163.2864077669903 -0.4366319307788321 0.6218636243821624 15.144324066085185 17.684684551282963 0.6291688220584918 0.2964583409243676 0.154423116545592 0.2385239021158064 0.1081750432230533 0.0041454634764224 +Obesity 0 5 1.9677581290057864 0.0490958739609603 2.2111650485436893 5.480582524271845 -0.2999198574912856 0.5232375343159741 1.4636606594962631 1.8373449741051235 0.8908763213650007 0.2908658327046029 0.1635258499471353 0.3009165941166509 0.5985687060361295 0.843131157648165 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..400c42eb1383371d4924c73b816459f042e7e68c --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 117, + "title": "Average number of proteins per term", + "value": 22.70940170940171 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..91309fed8a712a149c3b06d6ef112997c2d691d9 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4b3882242e9ccfaf3901ae61d2caace4dbd58fb0 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Hereditary nonpolyposis colorectal cancer 0.8732827014493507 2.870676382056086 0.0040959461532348 0.3813464335659327 0.0367439407851336 3 P54277 1 +Hermansky-Pudlak syndrome 0.8642196359295664 2.8501074485405424 0.0043704461984455 0.4009815430524978 0.0367439407851336 2 O14617 1 +Albinism 0.8642196359295664 2.8501074485405424 0.0043704461984455 0.4009815430524978 0.0367439407851336 2 O14617 1 +Kartagener syndrome 0.8182632050134276 2.6401100805185527 0.0082879102078088 0.6223268608885796 0.0510360786480859 2 Q86Y56 1 +Primary ciliary dyskinesia 0.8144667502296417 2.6011386221458515 0.0092914900552387 0.664517756533082 0.0517668731649017 3 Q86Y56 1 +Mental retardation 0.2969924131431057 2.4239273770856857 0.015353675522185 0.8363971372722413 0.0645505659021111 175 P36507,Q3SYG4,P68400,Q9UPP1,Q9Y263,Q8IY37,Q93008,A5YKK6,P51532,O75909,Q12873,Q13535,Q4G0J3,Q9Y4A5,Q9H1B7,Q9NR45,P57081,Q9UET6,Q9ULK4,P26196,Q14839,P42858,P08243,P41252,Q14204,Q96IJ6,P27635,P26640,P67870,Q96F86,Q8IWS0,Q9Y4X0,Q7Z6Z7,P42345,Q00610,Q05639,O60826,Q06787,O14646,Q13555,P60953,Q9C0E8,Q92974,Q9UID3,Q96C86,Q7LBC6,Q2M389 47 +Alport syndrome 0.7752256921436587 2.416512750738561 0.0156699773968662 0.8424328830764705 0.0645505659021111 3 Q9Y4X0 1 +Autism 0.7729954253354865 2.384482931329467 0.017103141392867 0.8671291223149551 0.0645505659021111 4 Q9HCK8 1 +Kallmann syndrome 0.7244776119403034 2.1720252053927194 0.0298537617891818 0.971162814552306 0.097024725814841 3 Q9P2D1,Q9BZH6 2 +Diamond-Blackfan anemia 0.6991473743398433 1.818968559180614 0.0689162269493448 0.9997646660063276 0.1914888959451306 17 P08708,Q07020,P62847,P62081,P61353,P62854,P42766,P61254,P61313 9 +Joubert syndrome 0.6466726350343113 1.8094813118664343 0.0703762609029112 0.9998041412239864 0.1914888959451306 2 O43924 1 +Aicardi-Goutieres syndrome 0.6165892382636686 1.6084286464183084 0.1077413319124054 0.9999983877931607 0.2449288159517574 4 Q5TBB1 1 +Primary microcephaly 0.6295163375203533 1.538227329885306 0.1239930408628655 0.9999998123346532 0.2737204864331183 11 P47897,Q2VPK5,Q15021,Q00534,P42695 5 +Cancer-related genes 0.2307432843697718 1.528631044643895 0.1263559353995269 0.99999986318299 0.2737711933656417 394 P00374,Q15648,Q9H6R7,P67809,O15357,P51532,Q13535,Q12923,Q9ULK4,P53396,P20248,P40763,P46777,Q9NYV4,Q00534,Q07864,Q9NZJ4,Q9Y620,Q9NR09,Q9HCK8,P27695,Q04637,Q99996,Q6P2Q9,O95373,P04818,P21399,P36507,O95071,P28340,Q9Y4A5,P33992,Q14203,P13639,P17612,P15531,P12277,P55060,Q9Y2L1,Q01844,P29375,P27635,O43290,P78527,Q8IWS0,Q7Z6Z7,P55212,P42574,Q8IXJ6,P19784,P14635,Q13315,Q9UDY8,O96017,O14681,P21359,Q9P2D1,P52701,P15880,P49427,P62841,Q14839,Q13309,P67870,P18074,O14654,P17096,P30307,Q14240,O95067,P28482,P61803,Q9UGU5,P53350,Q6W2J9,Q99816,Q13616,P09874,P61353,P04183,P31751,P49327,Q9UER7,Q9Y5V3,O14965,O14980,P14174,P26196,P27708,Q06124,P49917,P42345,P50570,P55196,Q00610,Q14258,P22392,P22681,P31939,P35579,P40818,P63241,Q8IWI9 103 +Fanconi anemia 0.5807665401756248 1.4483181128732248 0.1475281043119873 0.9999999922452428 0.306805985790784 3 Q9NVI1 1 +Cone-rod dystrophy 0.5559534467323094 1.3451291489944417 0.1785835314453161 0.9999999998990936 0.3482378863183665 2 Q13432 1 +Leber congenital amaurosis 0.5449119665771311 1.2880424301137556 0.1977311936316943 0.9999999999936112 0.3788317532923879 2 P20839 1 +FDA approved drug targets 0.2606508273909328 1.270276015064462 0.2039863286959011 0.9999999999974432 0.3788317532923879 130 P00374,P36507,P23921,P09874,O75116,Q969G6,P49327,P26358,Q9UPY5,P49721,O14980,P20645,P13639,P20618,P53396,Q00534,Q14353,O00764,Q07864,P42345,P42574,P62942,P78559,Q13464,P28482,P31939,Q99707,P39023,O95864,P04035,P04818 31 +Cushing syndrome 0.5387910902281214 1.2073184808430126 0.2273095161100427 0.9999999999999212 0.402957778558712 4 O00170,P40818 2 +Systemic lupus erythematosus 0.5234994332680762 1.1525300040994126 0.2491033476152679 0.9999999999999972 0.4350013682236769 3 P05455 1 +Hypotrichosis 0.5174780806165239 1.0519025538962392 0.2928442600846708 1.0 0.4894682632843783 6 P46778 1 +Microphthalmia 0.5001609242254962 0.963631242260964 0.3352308375447819 1.0 0.5447501110102705 6 O60493,Q6W2J9,Q5SRE5,A6NHR9 4 +Ciliopathy 0.5180008421714013 0.927554038666407 0.3536389483278133 1.0 0.561936740880779 13 P57076,Q3SYG4,Q01968,O43924,Q86Y56 5 +Congenital myasthenic syndrome 0.4829717723833322 0.9215582965908754 0.356759019894334 1.0 0.561936740880779 4 Q06210 1 +Lissencephaly 0.4965479226982059 0.9058434155856904 0.3650187376661471 1.0 0.561936740880779 8 O43505,Q9UPN3,Q00535,Q9BSJ2,P43034 5 +SCID 0.4654392625490652 0.8337593860232252 0.4044165859479229 1.0 0.6066248789218844 4 P78527 1 +Autism spectrum disorder 0.4732495550645829 0.7058056513179971 0.480309007153594 1.0 0.669001831392506 13 P27635,Q9Y4A5,Q9HCK8 3 +Glycogen storage disease 0.4364445219363002 0.5808045604103076 0.5613721811602843 1.0 0.7463698317699234 10 P04075,P06737,Q93100,P46976,P35573,P08237 6 +Ectodermal dysplasia 0.4138969869903985 0.5132509384317369 0.6077757981663605 1.0 0.7729322650593933 8 Q9H4L7,P36507,Q14692 3 +Parkinsonism 0.3961592884155447 0.4087740092220152 0.6827055152584003 1.0 0.8389704974667093 10 O75569,Q9Y3I1 2 +Dystonia 0.3830562989623479 0.4010462821563428 0.6883860492034537 1.0 0.8389704974667093 7 O75569 1 +Diabetes mellitus 0.3824807435462425 0.3431090588695455 0.7315164163540309 1.0 0.8816322626505353 11 P49841,O15357,P31751,P40763,P13807 5 +Oncogene 0.3528902887523348 0.3338917950426625 0.7384612114508757 1.0 0.8816322626505353 4 Q96Q89 1 +Premature ovarian failure 0.3434378446429638 0.3157606598522666 0.7521841803773677 1.0 0.8873204269537494 3 Q06787 1 +Glaucoma 0.336615935541628 0.3075910552593895 0.7583935273108968 1.0 0.8873204269537494 2 Q9UHD2 1 +Parkinson disease 0.333292065943321 0.2168684157846468 0.8283108923760418 1.0 0.9501213177254596 8 Q9Y3I1 1 +Disease variant 0.1770596661348608 0.2022508011675896 0.8397206600565563 1.0 0.9538574488021077 862 P00374,Q9UM54,Q3SYG4,O15357,O60701,P10589,Q13614,P51532,O75909,P38935,Q13535,Q12873,P26358,Q13190,Q86Y56,Q9Y6D5,Q9H1B7,P42695,Q9NVI1,Q9NR45,Q9NRZ9,Q9ULK4,Q9UPN3,P42766,P42858,O95163,P08243,Q6XZF7,P40763,Q5TAQ9,P46777,Q96RD7,Q00534,Q9Y6B6,Q9Y3I1,Q9H269,Q9Y4X0,Q07864,Q9NZJ4,P62854,O00443,Q08AM6,O95248,O14802,Q9HCK8,O60826,Q9NW08,Q99707,Q9BTW9,Q8NCE2,Q01433,O75569,O75880,Q9Y263,O43772,P42356,A1X283,P28340,O75165,Q9Y4A5,Q14746,Q15021,O76094,Q9Y5L0,Q14204,P46778,P35573,P27635,P26640,O00217,P78527,Q8IWS0,Q9BUK6,Q7Z6Z7,Q8NHU6,Q99575,Q8TEW0,Q13315,Q9UDY8,Q15477,O96017,O60231,O14646,P62266,Q9C0E8,Q9HC07,Q9UID3,Q96C86,Q7LBC6,O14681,Q9UPP1,Q8IY37,Q93008,A5YKK6,O43933,P21359,Q01968,Q9P2D1,Q8IUX1,P52701,Q14999,Q14839,Q9UBS4,P67870,P18074,O14654,P04350,O00764,P53621,P57678,Q96C23,Q13501,O60333,P26373,P50851,P46821,P08237,Q6W2J9,Q2M389,Q07020,P31751,Q7KZN9,Q13144,Q4G0J3,P57081,P06737,P07814,P26196,P27708,P41252,Q96BN8,Q96IJ6,Q96F07,Q96F86,Q06210,Q14353,Q06124,P49917,O43505,O94903,P26639,P42345,O00203,P50570,Q00610,P50747,Q5SRE5,Q9BV10,P22681,P31939,P35579,P40818 152 +Williams-Beuren syndrome 0.3213803990342871 0.1842691836488726 0.8538022878298035 1.0 0.9605275738085288 8 Q96P11 1 +Ehlers-Danlos syndrome 0.2970149253731372 0.1735033725336796 0.8622557771868713 1.0 0.9607992945796564 3 Q8NCH0,Q96L58 2 +Non-syndromic deafness 0.328277732827248 0.1445425155670831 0.8850720863527519 1.0 0.967789103768897 15 Q9UM54,P35579,P35241,Q9Y4A5 4 +Leukodystrophy 0.3129462891896514 0.0900875861795599 0.9282176139001224 1.0 0.9883622947378332 20 P04350,P07814,Q9NW08,Q53FT3,P49770,Q13144,O14802 7 +Congenital disorder of glycosylation 0.3022477638856554 0.0821545862681304 0.9345237862196358 1.0 0.9883622947378332 18 Q14746,P27708,Q9HC07 3 +Tumor suppressor 0.3264586857425504 0.0813828652930052 0.93513747542141 1.0 0.9883622947378332 29 Q9ULC4,O96017,Q8IZH2,Q9NZB2,Q13315,P54277 6 +Charcot-Marie-Tooth disease 0.2860442369763143 0.0437565981994929 0.9650984235436526 1.0 0.9883622947378332 26 O00764,P50570,Q14204,O95248,P38935,O60333 6 +Neuropathy 0.2982292839037181 0.0332210383485306 0.9734983212047714 1.0 0.9883622947378332 51 O60231,O00764,Q00796,P50570,O95163,Q13614,P35251,Q14204,P38935,Q5TAQ9,O95248,P26358,O60333 13 +Cataract 0.2655754176739376 0.0280852352056585 0.9775941700283276 1.0 0.9883622947378332 29 Q8NHU6,O00443,Q01968,Q6XZF7,Q5SRE5,P18074 6 +Deafness 0.25914597582425 0.017062785902079 0.9863865271356989 1.0 0.9883622947378332 50 Q06124,Q9Y4X0,P62266,P35579,O43933,P26358,Q9Y4A5,P18074 8 +Dwarfism 0.2454534661438789 0.0145862177362844 0.9883622947378332 1.0 0.9883622947378332 51 Q08209,P54132,P48651,Q13535,Q4G0J3,Q6DN90,P33992,Q9NR45,Q14999,P40763,P18074,Q99741,Q9NUQ7,O00443,Q99575,P49589,P26373,P62266,Q7LBC6 19 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cafb9c3aca6230cc4302ecb6fba5bff692d274d0 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Atrial septal defect", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital erythrocytosis", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABHD12", "ABHD5", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "AMMECR1", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APRT", "ARCN1", "ARFGEF2", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARSA", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATR", "ATXN10", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS9", "BCAP31", "BCAS3", "BCAT2", "BCKDHB", "BCL10", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "CA8", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT5", "CD320", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC42", "CDC6", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDKAL1", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHM", "CHMP2B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COG2", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "CORO1A", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCAF8", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "ECT2", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGLN1", "EHHADH", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "EPB41", "EPB41L3", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC2", "ERCC3", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC6B", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP1A", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FUBP1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATA6", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GCLM", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GINS1", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNB1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GPT2", "GRB2", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GUF1", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD11", "HPRT1", "HSD17B10", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2R", "IGHMBP2", "IKBKG", "ILF3", "ILK", "IMPDH1", "IMPDH2", "INF2", "INPPL1", "INTS1", "INTS8", "IPO7", "IQSEC1", "IRF2BPL", "IRS4", "ISCA2", "ITGB1", "ITPA", "ITPR2", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LIG4", "LIMD1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MALT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MASTL", "MATR3", "MBD1", "MBNL1", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED23", "MESD", "MFN2", "MGA", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYH10", 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0000000000000000000000000000000000000000..e1c68a33b4572a3ad1fa8a55f3ba2e7cee356c0b --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 98, + "title": "Average number of proteins per term", + "value": 40.90816326530612 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..59bc6c7754d7fa712ecf5f8c45d62fd950aed52f --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fe435b4572310fae91874e169babb9ad28828421 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transferase 0.3462722561003585 5.453539272305119 4.937703470205469e-08 4.838937812668504e-06 4.83894940089936e-06 405 O75116,Q00535,Q13535,P26358,Q13126,Q9UII4,Q9GZZ1,Q15386,Q9BWH6,Q9H2P9,Q9H1B7,Q9NR45,P78362,Q9UET6,Q96JP5,P53396,Q9NYV4,O95260,Q00534,O94822,Q96P11,Q99873,O60942,Q07864,Q8N1G2,Q9H9T3,O00443,Q9UJ70,Q7KZI7,Q8IY81,O14802,O14976,Q7Z2T5,P11216,Q7L2J0,Q9NR09,P35790,Q13464,Q9NW08,Q99707,Q9BQC3,Q9Y223,Q14527,P04818,P11908,P36507,P49841,Q96FX7,P68400,Q13523,Q86W50,P42356,O95071,Q969G6,P28340,O60294,Q9Y314,Q9UBP6,Q5TAX3,P17612,P15531,P12277,P46087,P35573,P78527,Q9NT62,Q9H2G2,Q5T4S7,Q7Z6Z7,Q15418,Q8IXJ6,O14929,P19784,O60678,Q13315,Q9ULT8,P11802,O14744,Q96SB4,Q7Z4G4,Q15047,Q13418,O96017,O75925,O75592,Q8WVM0,Q96GX5,P49761,P00492,P07741,P43490,P48651,P61081,Q8TBX8,Q9HCL2,Q9HA64,Q9BV86,P49427,O00764,P17858,O15111,P28482,P49903,Q99986,P53350,P08237,Q96EP0,P09874,P04183,P30419,P31751,P49327,O14965,O43709,P06737,P27708,Q86TU7,Q8TEA1,Q06210,Q14353,O43505,P42345,Q16513,Q9BV10,Q14258,Q16512,P22392,Q13555,P22681,P31939,P51003,Q99570,Q5T447,Q9UKK9 134 +Ribosomal protein 0.4783034959164266 5.050968995446279 4.395744235862453e-07 4.3077375122840574e-05 2.1539146755775014e-05 116 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,Q9HD33,P26373,P18124,P62266,P62277,P61513,P39023,P61254,P62899,P82675,Q9NP92,Q9Y3U8 51 +Kinase 0.4623255437461133 4.838100303038492 1.3108598893030177e-06 0.0001284561021594 4.282142305059791e-05 120 P36507,P49841,P68400,Q13523,O75116,P04183,P31751,Q969G6,P42356,Q00535,Q8TBX8,Q13535,Q9HA64,P78362,O14965,P17612,P12277,P15531,Q9NYV4,Q00534,P78527,Q9H2G2,O00764,P42345,O00443,Q15418,Q9UJ70,Q7KZI7,P19784,Q16513,O14976,Q13315,P11802,P17858,Q96SB4,O15111,Q13418,O96017,Q16512,P22392,Q13555,Q13464,P35790,P28482,P49903,Q96GX5,Q99986,P49761,Q99570,Q9Y223,P53350,P08237,P11908 53 +Ribonucleoprotein 0.3211401165959016 3.1221429603010287 0.0017953973197388 0.161471807520997 0.0293248228890683 182 P18621,P08708,P62314,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P38935,P62701,P62241,Q96HR8,Q02543,P15880,P62081,P62269,O76094,P62841,P42766,P83731,Q02878,P46779,P32969,P46777,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P09012,P62910,Q9HD33,Q06787,P26373,P62266,P18124,P62277,P61513,P39023,P61254,P62899,P82675,Q9NP92,Q9Y3U8,P49207 58 +Activator 0.3403296850449876 2.7461892438619295 0.0060291974236967 0.4471395993716217 0.0552342589466985 113 Q8NE71,Q9UPT9,P27695,P67809,Q96EK7,Q99504,P10589,Q6P1K2,P35251,P85037,P38935,P26358,Q9Y2X0,Q92616,Q9Y4A5,Q14527,P29375,Q9HCK8 18 +Cyclin 0.8339802926246531 2.6712706509691264 0.0075564691448093 0.5244798695276698 0.0552342589466985 4 O75909,O95067,P14635 3 +Helicase 0.5154753877477533 2.6605087279472746 0.0078022705065172 0.5358841180721061 0.0552342589466985 89 Q9H6S0,P42694,Q8IY37,P46063,P51532,P54132,Q12873,P38935,Q9P2D1,Q9GZR7,P33992,Q9NRZ9,O14981,P26196,Q96L91,Q14839,Q9NUL7,Q8N3C0,Q7L014,Q92620,Q6P158,P18074,Q92499,Q9HCE1,Q7Z478,Q9Y620,Q9H4L7,Q8IX18,Q14240,P33993,Q15477,Q9HCK8,Q14562,Q9UNY4,O60231,O14646,Q14147,Q7Z7L1,Q86WJ1,Q14527 40 +DNA-binding 0.2789002112188677 2.633369838903335 0.0084542233081681 0.5648375937826957 0.0552342589466985 244 Q15648,P67809,Q9Y237,P09874,O43670,Q92547,Q8IZH2,P46063,P10589,P20585,P38935,Q12873,Q13535,Q8IYB3,P26358,Q9UBD5,Q12789,Q96FZ2,P28340,Q9P2D1,Q9BUI4,Q9BWH6,Q9NVI1,P52701,O14981,Q96L91,Q14839,P40763,Q08945,P78527,Q92499,Q9BQ70,Q8IWS0,P18074,P17096,Q07864,Q7Z6Z7,Q9H4L7,Q13315,Q9UNY4,Q9HCK8,O75925,P09429,P22392,P27695,O14646,P28482,Q9UGU5,P35251,P85037,Q66K74,Q8IWI9,Q9Y2X9,Q14527,P54277 55 +DNA-directed DNA polymerase 0.8191961760419051 2.60259732957661 0.0092520549396422 0.597846676696823 0.0566688365053085 4 Q07864 1 +Hydrolase 0.2552858253704388 2.3999602108054727 0.0163968540549299 0.8021431489288169 0.0710631711406593 401 Q70CQ2,Q9UPT9,O15357,P46063,Q13614,O15091,P51532,P38935,Q12873,Q12923,Q96DE0,Q96FZ2,Q9GZR7,Q9NRZ9,O75818,Q01804,Q6P158,O60942,Q07864,Q7Z478,Q9H4L7,Q8IX18,Q9HCK8,P27695,Q14147,Q14674,Q7Z7L1,Q86WJ1,Q8NCE2,Q14527,Q01433,Q99504,Q8IZH2,Q2TAA2,P28340,Q96L91,Q99956,Q9Y2L1,Q7L014,P35573,Q9HCE1,P55212,P42574,Q99575,Q9UDY8,Q15477,O60231,O14646,Q9Y4P1,P52888,O60841,Q9NY33,Q96C86,Q9NZC3,Q8IY37,Q93008,Q01968,P50579,Q9UNI6,Q9P2D1,Q14839,Q9NUL7,Q8N3C0,P18074,P30307,Q96RU2,Q9GZR2,Q14240,O00154,P29372,Q9H9L3,Q9UIV1,P49327,O14981,P51452,P26196,P27708,Q96BN8,Q6GQQ9,Q06124,P50570,Q96FW1,Q9UNY4,P31939,P40818,P29144,P42785,Q9H6S0,Q9UKK9 89 +Cytokine 0.696511217162921 2.0118184833885 0.0442390748086425 0.9881360702425313 0.1548367618302488 4 P43490,P14174 2 +Signal transduction inhibitor 0.6702218320817794 1.8805519618642657 0.0600328916433605 0.9976823898990318 0.1897813993886882 4 P49407 1 +Myosin 0.6726430833356382 1.793834651275845 0.072839564389084 0.9993958019713935 0.2230711659415698 9 Q9UM54,O43795,O94832,P35580,P35579,Q92614 6 +tRNA-binding 0.6857426386707277 1.7288173440003187 0.0838417910104973 0.9998124544435772 0.2489847126978407 19 P26639,Q9HAV4,O43592,P38935,Q7Z7L1,Q7Z2T5,Q7Z4G4,Q9UBP6 8 +Serine/threonine-protein kinase 0.556829885802964 1.68789375930043 0.0914316248346867 0.9999170060606616 0.2560085495371227 72 P36507,P49841,P68400,Q13523,O75116,P31751,Q00535,Q13535,O14965,P78362,P17612,Q9NYV4,Q00534,P78527,Q9H2G2,P42345,Q15418,Q7KZI7,P19784,Q16513,Q13315,O14976,P11802,Q96SB4,O15111,Q13418,O96017,Q16512,Q13555,Q13464,P28482,Q99986,P49761,Q99570,P53350 35 +Threonine protease 0.5637181712044194 1.3603153754146438 0.173730144877751 0.9999999924499984 0.3959431208841769 3 P28072 1 +Tumor antigen 0.555026841234828 1.2912168208046366 0.1966285039660218 0.999999999519372 0.4379453042879577 4 Q9Y5V3 1 +Thiol protease 0.6014700949530001 1.199753315588212 0.2302351599695571 0.999999999992704 0.4905009929786216 34 Q70CQ2,Q9UPT9,P55212,P42574,Q9Y4P1,Q93008,P40818,Q14674,Q01804,Q96BN8,Q96RU2,Q96FW1,Q6GQQ9 13 +Protein phosphatase 0.5785525690812899 1.1294350398160702 0.2587143583683355 0.9999999999998186 0.5203798199105032 22 Q06124,P30307,O60942,Q99504,P51452,Q08209,Q99956,Q12923,Q9UNI6,O00743 10 +Methyltransferase 0.5729753214181665 1.125942378487139 0.2601899099552516 0.9999999999998508 0.5203798199105032 49 Q96FX7,Q86W50,P26358,O60294,Q9BV86,Q9H2P9,Q9UBP6,Q9UET6,O43709,P46087,Q86TU7,Q8TEA1,Q08J23,Q99873,Q96P11,Q14353,Q8N1G2,Q8IY81,O60678,Q7Z2T5,O14744,Q7L2J0,Q7Z4G4,Q15047,Q99707,Q8WVM0,P04818 27 +Nucleotidyltransferase 0.5355103518175357 0.8772357815464789 0.3803585847871564 1.0 0.6924249850630225 25 O60942,Q07864,Q9NW08,O14802,P28340,Q9BWH6 6 +Allosteric enzyme 0.5294227539234847 0.8625108278800374 0.3884064772307505 1.0 0.6924249850630225 23 Q14012,P14618,P23921,P06737,O60701,Q13085,P27708,Q13153,Q01813,P14735,P17858,Q9Y223,P08237,Q9Y3Z3,P11216,P13807 16 +Motor protein 0.54022649842733 0.8621484024361541 0.3886058589639412 1.0 0.6924249850630225 33 Q9UM54,O43795,P63167,Q15058,O94832,P35580,Q9BW19,P35579,P50570,Q92614,Q9Y496,Q14204,Q96Q89,O43237,P63172,O00139,O60333 17 +Guanine-nucleotide releasing factor 0.5055821989871572 0.7513360576347698 0.4524504340866664 1.0 0.7534016356675404 22 O75592,Q14185,Q96N67,Q6XZF7,Q9NPQ8,O95248,Q92538,Q9Y6D5 8 +Chromatin regulator 0.2921948114281008 0.7324909338223506 0.4638689743598523 1.0 0.7576526581210921 96 Q9UPT9,Q9UPP1,Q99504,P51532,P26358,Q9P2D1,Q9UER7,Q9Y4A5,O43709,P25440,Q96L91,Q14839,Q8NB78,P29375,Q9H4L7,Q9HCK8,Q16512,O14646,Q6W2J9,Q7LBC6,Q14527 21 +Serine protease inhibitor 0.4258430319307618 0.6862266856112377 0.4925701724052549 1.0 0.7913422441920488 2 P30086 1 +Decarboxylase 0.4297303021253146 0.6011985228805024 0.547707768198326 1.0 0.8257747889759377 7 P06132,P11172,Q16822,Q6P996 4 +rRNA-binding 0.4622811362633997 0.5651182341902115 0.5719933468206642 1.0 0.8493234543700772 20 P62269,Q9NUL7,P62701,P62280,P62917 5 +Exonuclease 0.4617586157219628 0.5428505491174005 0.5872327060215867 1.0 0.8589373908972463 22 P27695,Q8IZH2,Q9Y2L1,Q9GZR2,Q9H9L3,P28340 6 +Initiation factor 0.4721266369939118 0.5088045072139065 0.6108892598005897 1.0 0.8803992273596735 38 Q9ULC4,P41567,O15371,P41214,Q04637,Q7Z478,P49770,Q13144,Q9BY44,O60841,Q14152,Q14240 12 +Multifunctional enzyme 0.452209892867047 0.4435937209350454 0.6573363462569684 1.0 0.9080821688177092 30 O60942,P07814,P31939,P27708,P50747,P49327,P35573,Q14527 8 +Actin capping 0.3934162893289338 0.442819544812256 0.6578962651638505 1.0 0.9080821688177092 7 P47756,P35241,O15020,P47755 4 +Aminopeptidase 0.4014393351933033 0.4025004348406367 0.6873157684065054 1.0 0.9355131292199655 12 Q9UIQ6,P29144,P50579,Q9H4A4,Q9NQW7,Q9NY33,Q86TI2 7 +Aminoacyl-tRNA synthetase 0.4382541269624957 0.3766190613661259 0.7064567202110859 1.0 0.9483939531600878 32 P47897,P49589,P26639,P07814,P41252,O43776,P23381,P54136,Q9NSD9,Q9P2J5,P26640 11 +Voltage-gated channel 0.3601321212382697 0.3608330849428359 0.718224228458054 1.0 0.9511618160660716 4 O00299 1 +Growth factor 0.3541613156353527 0.3228637174501366 0.7467984552335181 1.0 0.975816648171797 5 P06744,P51858 2 +Nuclease 0.3935405248116028 0.205431484999477 0.8372350233350654 1.0 1.0 37 P27695,Q8IZH2,O15091,Q9Y2L1,Q9GZR2,Q9H9L3,P28340 7 +Protease 0.2745089687508654 0.1910227899464673 0.8485077381234079 1.0 1.0 89 Q70CQ2,Q9UPT9,P17655,Q93008,Q92905,P50579,Q9H4A4,Q96FZ2,Q86UV5,Q01804,Q96BN8,Q6GQQ9,P55212,P42574,Q96RU2,Q9UDY8,Q96FW1,Q9Y4P1,P40818,P29144,P42785,Q14674,P52888,Q9NY33,Q86TI2 25 +RNA-binding 0.1793034055841715 0.1447425315076226 0.8849141574448178 1.0 1.0 382 P00374,O75569,Q9UIV1,P67809,O43592,Q8IZH2,Q86W50,O75153,P42696,P38935,P62701,Q8IYB3,Q4G0J3,Q8IXT5,Q96DE0,Q96HR8,Q9UBP6,O14980,Q9HAV4,P07814,Q8IWR0,P62269,O75818,P26196,Q9NUL7,Q9Y2L1,Q7L014,P62280,Q01844,Q8TEA1,Q8WUA2,Q96F86,P62917,Q96P11,P62750,Q9HCE1,Q86TB9,P26639,Q8NHU6,Q9NZB2,Q99575,Q8IWZ3,Q14240,Q7Z2T5,Q15020,Q92917,Q7Z4G4,Q15477,P27695,P18124,Q14147,Q6PKG0,P51003,P63241,Q14152,Q7Z7L1,Q8IY67,Q9Y2V2,Q9H6S0,Q9HAU5,Q9UKK9 61 +Tyrosine-protein kinase 0.3001443748290163 0.1135820170100289 0.9095691434322082 1.0 1.0 11 P36507,P49761 2 +Endonuclease 0.3062767567292265 0.0923087250212994 0.92645275640497 1.0 1.0 17 P27695 1 +Developmental protein 0.2553181417762103 0.0787733860323838 0.9372128731189246 1.0 1.0 87 P49841,Q9Y263,Q99504,A5YKK6,P31751,Q99426,Q69YN4,Q9Y314,Q9NRZ9,Q14997,Q8NB78,P29375,P27635,Q96EK5,O94967,Q96N67,Q7KZI7,Q13555,Q9C0E8,Q92974,P85037 21 +Dioxygenase 0.2822006775232094 0.0502730399930811 0.9599048075640728 1.0 1.0 21 O00625,Q9UPP1,Q8IUF8,P29375,Q7LBC6,Q6P6C2 6 +Rotamase 0.271387066856637 0.0382822832707828 0.9694626163330764 1.0 1.0 23 Q15257,P62942,Q96BP3,Q9Y237 4 +GTPase activation 0.2648835010779535 0.0318513551384352 0.974590591911806 1.0 1.0 25 Q9BTW9,Q8TC07,Q15042 3 +Ligase 0.2538361000785722 0.0229331419750181 0.9817036038690448 1.0 1.0 76 Q9Y285,Q13085,O43776,Q9P2J5,P22314,Q9Y3I0,P07814,P17812,P27708,P41252,P08243,P18858,P23381,P54136,Q8TBC4,P26640,P49917,P26639,P50747,Q14258,P47897,P49589,Q9NSD9,O15067 24 +Calmodulin-binding 0.234385305896434 0.0177134252499903 0.9858674705278356 1.0 1.0 33 Q9UM54,O43795,Q5T4S7,O94832,P35580,Q13555,P35579,P46940,Q01844 9 +Glycosyltransferase 0.2247956076229353 0.0153100846366187 0.9877847970503192 1.0 1.0 38 P00492,P07741,O43505,P06737,P09874,P43490,Q9Y673,Q13126,Q9BV10,P35573,P11216,P13807 12 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ed9fdbd93c586045000c79da984a47c085c0529f --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligand-gated ion channel", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APEH", "APEX1", "APRT", "AQR", "ARFGAP1", "ARFGEF2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATE1", "ATG3", "ATG4B", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BANF1", "BAZ1B", "BAZ2A", "BCAT2", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BPHL", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CAD", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CERS1", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHM", "CHML", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CROT", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CSTF2T", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTSA", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGLN1", "EHHADH", "EHMT2", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "F11R", "FADS2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRG1", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "INTS11", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "IVD", "KARS", "KAT7", "KATNA1", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KRR1", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD3", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MALT1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MATR3", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NARS2", "NAT10", "NAXE", "NCEH1", "NCL", "NCOA5", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NF1", "NFKB2", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NR2F1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM7", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMS1", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", 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"RANBP1", "RANBP2", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RFK", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPP40", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSBN1L", "RSF1", "RTCA", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBF1", "SC5D", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD5", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SOD2", "SON", "SORD", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SRXN1", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", 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overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500 +Ribosomal proteins 48 122 4.8445906594054975 1.2687297663571684e-06 54.21601941747573 126.59708737864078 -1.1013645810576873 0.3672949560938939 17.688909247563995 6.332440078033074 1.7905145664594482 0.3696976543931279 0.048700724445905 5.311989985680514e-06 1.677932154178973e-07 1.9911566206278604e-21 +Enzymes 263 989 2.6816994729597807 0.0073249230349843 180.46601941747576 916.0339805825242 -0.3890709639022823 0.4315149002113257 67.0110577071333 90.66568168613344 1.858068218066602 0.4271937700203886 0.0660422114095735 0.0592736451015216 0.0003670578424743 1.2680782572487884e-07 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fb955a47db5a25cbedf2a8dbd2769a092b65e0a0 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3353, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 509.9047619047619 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7b56246b483d72ab54d2608a916f618120cd58f5 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C101/C101_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e823949c8cd0292999956df0f607bf38b68da84c --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosomal proteins 0.4615164862943445 4.8445906594054975 1.2687297663571684e-06 2.664298706444149e-05 1.3321662546760768e-05 122 P18621,P08708,P46782,P62847,Q07020,P61353,P46776,P40429,P62424,P62701,P62241,Q02543,P15880,P62081,P62269,P62841,P83731,P42766,Q02878,P46779,P32969,P62280,P46778,P27635,P62917,P47914,P62750,P61247,P84098,P62854,P36578,P60866,P62851,P61313,P62906,P62753,P50914,P62910,Q9HD33,P26373,P18124,P62266,P61513,P39023,P61254,P62899,P82675,Q9Y3U8 48 +Enzymes 0.2230356114389679 2.6816994729597807 0.0073249230349843 0.1430618405016006 0.0307646767469342 989 P00374,Q70CQ2,Q9UPT9,Q8WUX2,O15357,O75116,O60701,P46063,Q13614,O15091,Q9BYN0,Q00535,P38935,Q13535,Q12873,P26358,Q13126,Q12923,Q96DE0,Q9GZR7,Q9GZZ1,Q15386,Q9H1B7,Q9H2P9,P49721,P78362,Q9NR45,Q9UET6,Q96JP5,Q86UV5,O75818,P53396,Q01804,P08243,Q9NYV4,O95260,Q00534,O94822,Q6P158,Q99873,Q92499,O60942,Q07864,Q8N1G2,O00443,Q9UJ70,Q7Z478,Q9H4L7,Q8IX18,Q7KZI7,O14802,O14976,P11216,Q9NR09,Q9HCK8,P28066,P47897,P35790,Q14147,Q13464,Q00796,Q9NW08,Q99707,P60953,Q14674,P49720,Q9BQC3,Q86WJ1,Q9Y223,Q86TI2,Q14527,Q01433,P04818,P11908,P21399,P36507,P17655,P49841,Q96FX7,P61457,P68400,Q99504,Q13523,Q86W50,Q92905,P42356,O95071,O43776,Q969G6,P28340,Q9H4A4,Q9NQW7,Q9P2J5,O60294,Q9Y314,Q9UBP6,P33992,O00625,Q5TAX3,O95394,P17612,P25787,P15531,P20618,P12277,Q99956,P50336,Q7L014,Q8NB49,P35573,P29375,Q92620,P26640,O00217,P78527,Q9GZT9,Q9H2G2,Q9HCE1,Q5T4S7,Q9NZB8,Q7Z6Z7,P55212,P42574,Q16881,Q15418,Q99575,O00429,Q8IXJ6,Q15185,P19784,O14929,Q13315,Q9ULT8,O95707,Q9UDY8,P11802,O14744,Q96SB4,P33993,Q15047,Q13418,O96017,Q14562,O75592,O60231,O14646,Q9Y4P1,Q96GX5,O95864,P52888,P49761,O60841,Q9NSD9,Q9Y5B9,Q9NY33,Q96C86,Q7LBC6,Q6P6C2,O95881,O15067,O00743,P00492,P07741,Q9UPP1,Q9NZC3,P23921,Q9Y237,P16930,Q8IY37,Q93008,P28072,P43490,Q13085,Q08209,Q13526,Q01968,P50579,P62136,P54132,P48651,Q9UNI6,Q96BP3,P61081,Q8TBX8,Q9P2D1,Q16850,Q9HCL2,Q9HA64,Q9BV86,P49427,Q14839,Q9NUL7,Q6NTF9,Q8N3C0,Q9P2T1,P18074,P30307,O00764,Q15257,Q96C23,Q96RU2,Q14240,P17858,P62942,O00154,O15111,P28482,P29372,P30046,P49903,Q99986,P53350,P08237,P04035,Q2NKX8,Q96EP0,Q9UIV1,Q13907,P09874,P04183,P30419,P31751,P49327,O14965,P06737,P07814,P14174,P51452,P17812,P26196,P27708,P41252,P18858,Q96BN8,Q86TU7,Q8NB78,Q8WUA2,Q06210,Q6GQQ9,Q14353,Q06124,P49917,P26639,P42345,P50570,P50747,Q16513,Q9BV10,Q96FW1,Q14258,Q16512,P22392,Q13555,P22681,P31939,P40818,P29144,P42785,P51003,Q99570,Q5T447,Q9H6S0,Q9UKK9 263 +Cancer-related genes 0.2307432843697718 1.528631044643895 0.1263559353995269 0.9413827897550684 0.2653474643390066 394 P00374,Q15648,Q9H6R7,P67809,O15357,P51532,Q13535,Q12923,Q9ULK4,P53396,P20248,P40763,P46777,Q9NYV4,Q00534,Q07864,Q9NZJ4,Q9Y620,Q9NR09,Q9HCK8,P27695,Q04637,Q99996,Q6P2Q9,O95373,P04818,P21399,P36507,O95071,P28340,Q9Y4A5,P33992,Q14203,P13639,P17612,P15531,P12277,P55060,Q9Y2L1,Q01844,P29375,P27635,O43290,P78527,Q8IWS0,Q7Z6Z7,P55212,P42574,Q8IXJ6,P19784,P14635,Q13315,Q9UDY8,O96017,O14681,P21359,Q9P2D1,P52701,P15880,P49427,P62841,Q14839,Q13309,P67870,P18074,O14654,P17096,P30307,Q14240,O95067,P28482,P61803,Q9UGU5,P53350,Q6W2J9,Q99816,Q13616,P09874,P61353,P04183,P31751,P49327,Q9UER7,Q9Y5V3,O14965,O14980,P14174,P26196,P27708,Q06124,P49917,P42345,P50570,P55196,Q00610,Q14258,P22392,P22681,P31939,P35579,P40818,P63241,Q8IWI9 103 +FDA approved drug targets 0.2606508273909328 1.270276015064462 0.2039863286959011 0.9916951640052306 0.356976075217827 130 P00374,P36507,P23921,P09874,O75116,Q969G6,P49327,P26358,Q9UPY5,P49721,O14980,P20645,P13639,P20618,P53396,Q00534,Q14353,O00764,Q07864,P42345,P42574,P62942,P78559,Q13464,P28482,P31939,Q99707,P39023,O95864,P04035,P04818 31 +Plasma proteins 0.1801819599553839 0.6166614812533207 0.5374580328398597 0.9999999070661338 0.6782188764874104 1310 P41567,P67809,P62847,Q14185,O75116,Q8IYB3,P26358,Q13126,P42695,P49721,P50748,Q14241,P42858,Q9UH99,Q00534,P62917,Q9Y6B6,O60942,Q07864,Q9NZJ4,P84098,P48634,P61313,Q7Z478,O14802,Q92616,Q9Y613,P50914,P62910,Q9NR09,Q9HCK8,Q8NE71,P78559,O14617,P27695,Q5VZE5,P39023,P49720,P62899,P35251,P46940,Q9BZF3,Q9BPU6,P18621,P62314,Q9Y263,P42356,O43776,P28340,Q15369,O60294,Q9Y666,Q9Y4A5,Q9UBP6,Q9UBF2,Q14746,Q15021,P61970,P25787,P15531,O76094,Q96L91,Q9Y2L1,Q14204,Q7L014,Q9UBB9,Q01844,P35573,P27635,P26640,O43290,P78527,Q9HCE1,P42574,P36578,Q9P1Y5,Q9NZB2,Q99575,Q8TEW0,P14635,Q13315,Q15477,P49005,O96017,P52888,O60841,Q92538,Q9NY33,Q7LBC6,O95881,O15067,P23921,Q9Y237,A5YKK6,O43933,P20585,P21359,P50579,P53618,P62701,Q9UI26,Q9P2R3,Q9P2D1,Q9HA64,P52701,P15880,P62269,P83731,Q14839,P62280,Q9P2T1,Q9Y296,P67870,P78316,P62750,P04350,O00764,P53621,P57678,P61247,Q15257,Q92614,Q9NTJ3,Q14240,Q15020,Q9UQB8,P17858,P62942,O60333,P09429,O95067,P26373,P28482,P30046,P49903,P50851,Q6PKG0,Q9H223,Q99986,Q8TAG9,Q5JSH3,P46821,P04035,Q99816,Q13616,Q07020,P09874,O00170,P04183,P40429,P49327,Q13144,Q15008,P62241,Q02543,Q86VP6,O14965,O14980,O14981,P06737,P07814,P14174,P51452,P26196,P27708,P41252,P18858,Q9BPW8,Q9Y678,Q14353,Q06124,O43505,O60524,O94832,P26639,P42345,O00203,P50570,P55196,P60866,P62906,Q00610,Q16513,Q96FW1,Q9HD33,Q9UNY4,Q14258,Q14008,Q13555,P18124,P31939,P35579,P29144,P42785,P51003,P63241,O43396,Q86X10,Q9HAU5,Q9UKK9,Q9UM54,Q9Y383,Q15648,Q15398,P46782,O43670,O60701,P46063,P51532,P62424,Q00535,Q12873,Q9H3P2,Q86Y56,Q9GZR7,Q9H1B7,Q7Z4Q2,Q86UV5,P53396,O95163,P32969,P40763,P46777,P31949,Q08945,Q13564,Q99873,Q92499,Q96T51,Q9UKJ3,Q9H299,Q9Y295,Q9Y620,P47755,O60271,P09012,P11216,P20290,P26641,P28066,P47897,Q05639,Q13464,Q04637,Q00796,P62277,P60953,Q9BTX7,Q92974,Q96KM6,Q99996,Q9UIF9,Q9Y3Y2,Q6P2Q9,O95373,P04818,P21399,P17655,Q13523,Q15436,Q5T8P6,Q9BY42,Q92973,Q9BSJ2,Q9H4A4,Q9P2J5,Q9UPY5,Q9Y3Z3,P33992,Q14203,O00625,O15371,P13639,P20618,P12277,P55060,P46087,Q03518,Q13045,Q9BY44,Q8NB49,Q92620,Q96IU4,Q9BXS5,Q9UHB9,Q9GZT9,Q9H2G2,Q9H4M9,Q9UBC2,Q16881,O94973,Q15418,O00429,Q15185,O43432,P11802,O14744,Q13200,P33993,Q13418,Q14562,Q12830,P63167,P51858,P35580,Q9BW19,Q92522,Q99459,Q9BUJ2,Q9UNF1,Q9Y5B9,Q14684,O00401,P42694,O00410,P00492,P07741,P16930,P28072,P31146,O00299,P43490,P84085,P46109,Q08209,P62136 326 +RNA polymerase related proteins 0.373309855807957 0.2770214455635262 0.7817636391354996 0.9999999999999868 0.8640545485181838 14 Q9NW08,O14802 2 +RAS pathway related proteins 0.2595778791620041 0.0236425260482381 0.9811377507396531 1.0 0.9824626051937516 32 Q06124,P36507,Q96KP1,P28482,P17612,P60953,P55196,Q13153,P31751,P21359,P19174,P61586,O15111 13 +Transcription factors 0.2640426708628993 0.021981634940089 0.9824626051937516 1.0 0.9824626051937516 70 Q96JP5,P67809,P10589,P85037,P26358,Q9UPT8,Q9BQ70 7 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..72815ce071d977c82b659856ebca1769b82f3b07 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD28", "ANKRD46", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS9", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf174", "C1orf198", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C2orf69", "C5orf24", "C8orf33", "CA8", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPK", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX20", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EI24", "EIF1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRA10AC1", "FRG1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNB1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMP1", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGA", "MGAT1", "MGAT5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS11", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NEMP1", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGK", "PIGS", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOC", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSPRY1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF2L1", "SDHA", "SDHB", "SDHD", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", 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"UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", 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352 +Nuclear bodies 0.2560707259746481 1.2266090191511083 0.2199695776876551 0.9997247794506584 0.7258996063692619 142 Q9UIV1,Q92547,O75153,P20585,P61081,P38935,Q69YN4,Q9H3P2,Q9P2J5,Q96BP3,Q9UER7,Q8TEQ6,O00178,P18615,Q6XZF7,P35573,Q92674,P29375,Q969U7,O60524,P57678,Q9H299,P36578,Q53FT3,Q9Y295,Q16513,Q96RU2,O95248,Q7Z4G4,Q15477,Q14258,Q14562,P63167,P41214,P35579,P29144,Q9Y450,Q86V59,Q9H6S0,O75155,P54277 41 +Golgi apparatus 0.2383167596218424 1.0805870156456614 0.2798808608618484 0.999980305558472 0.8396425825855451 175 O14681,O15357,Q969G6,P53618,Q13535,Q13190,Q9H4A4,Q9HAD4,Q9Y4A5,Q9Y6D5,Q9H2P9,Q86VP6,Q9NRZ9,Q14746,P52701,Q14CX7,P18858,Q6XZF7,Q96GQ5,P22059,Q8N3C0,Q6NTF9,Q8TEA1,O95070,O43290,Q9Y678,Q96P16,P53621,O00203,P50570,Q69YN2,O14976,P26641,Q9NR09,O96017,O95067,Q96JB2,Q9BTX7,P50851,Q9HC07,P40818,Q99996,Q92538,Q5JSH3,Q9UID3,Q6P6C2 46 +Cytoplasmic bodies 0.4594931943010572 0.5524865435588001 0.5806150513464008 0.9999999999996484 1.0 20 P49917,Q86TB9,P26196,Q8NHU6,Q92973,Q96F86,Q9H6S0,Q9HAU5 8 +Mitotic spindle 0.4659724241554595 0.5361560897165734 0.5918506779717514 0.9999999999998564 1.0 25 Q14203,P04350,O14965,Q9BUF5,Q13885,Q00610,Q99741,Q9NR09,Q15477,Q6GQQ9 10 +Cytokinetic bridge 0.4174382507292675 0.3113294575748435 0.7555501753406166 1.0 1.0 29 Q14203,P04350,Q16512,Q96QE3,Q9BUF5,P17612,Q15019,Q13885,P60953,Q02878,Q99741,Q96Q89,O94915,Q6IBW4,Q6GQQ9 15 +Midbody ring 0.3268976691993847 0.2204637635650167 0.8255099905903986 1.0 1.0 6 P22392,Q15058 2 +Centriolar satellite 0.3428344513737639 0.1182421252137984 0.905875812959547 1.0 1.0 26 Q8NI35,Q15398,Q96QE3,Q03518,Q01968,Q12873,O60271,Q9Y5K6 8 +Cell Junctions 0.3063120982414789 0.0392644198794653 0.9686795735517412 1.0 1.0 50 Q8NI35,Q9UPN3,Q13555,P55196,Q8TEW0,Q9BTE3,P46940,Q00535,P53985,Q15369,Q9UJA5,Q7L2J0,Q66K74 13 +Microtubules 0.2692506904293987 0.0192125284601539 0.9846715631820844 1.0 1.0 57 Q14203,P04350,O75925,Q8WWK9,Q9BUF5,Q9BZH6,Q13885,Q9NRW7,P60953,Q02878,Q01968,Q99570,P31689,Q13564,Q6P158,Q9BY89,Q6GQQ9,O60333 18 +Nucleoli fibrillar center 0.2162912862411987 0.0110758341546762 0.99116294361 1.0 1.0 60 Q7Z3U7,O14646,P51532,P85037,A1X283,Q7L014,P46778,Q9UDY8,Q06210,P62750,O60333 11 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e37822aec4f0382556e3b4e1f514fd7f181df742 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAMDC", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD5", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AFTPH", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMMECR1", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD46", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFGEF2", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARRB1", "ARSA", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BDH2", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRK1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf174", "C1orf198", "C1orf35", "C2CD5", "C2orf49", "C5orf24", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP6", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD320", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPV", "CEP170", "CERS1", "CERS2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHM", "CHML", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAO1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD10", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "CORO1A", "CORO1B", "COTL1", "COX15", "COX20", "COX4I1", "COX5B", "COX6B1", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF2T", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS1L", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENOPH1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC2", "ERH", "ERI1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC9", "EYA3", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FRYL", "FSCN1", "FSTL1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATA6", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGPS1", "GHITM", "GIGYF2", "GINS1", "GINS3", "GINS4", "GIPC1", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPRIN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXIM1", "HGH1", "HIBCH", "HIKESHI", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXA10", "HOXD11", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITPR2", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0368", "KIAA0391", "KIAA1671", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "L2HGDH", "LAMTOR1", "LAMTOR5", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LIG1", "LIG3", "LIG4", "LIMA1", "LIMD1", "LIN28B", "LLPH", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYPLAL1", "LYSMD3", "LZIC", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCEE", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED21", "MED23", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGA", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL37", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NEMP1", "NES", "NF1", "NFATC2IP", "NFKB2", "NFKBIE", "NFS1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPM3", "NPTN", "NR2C2AP", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NSUN6", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD7B", "OTULIN", "OVCA2", "OXA1L", "OXCT1", "OXNAD1", "OXSM", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATJ", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PLXNA1", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPM1L", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC1L", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REEP6", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASEH2B", "RNF169", "RNF2", "RNF20", "RNF219", "RNF31", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SELENOF", "SENP3", "SEPHS1", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFN", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHTN1", "SIN3A", "SIN3B", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC5A6", "SLC7A11", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMG9", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRBD1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D23", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE4", "TLN1", "TM9SF3", "TMA16", "TMED10", "TMED2", "TMEM126A", "TMEM126B", "TMEM165", "TMEM167A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TRNT1", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTI2", "TTK", "TTLL12", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2V1", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR44", "WDR46", "WDR47", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR77", "WDR82", "WDR89", "WIPI2", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFP91", "ZFR", "ZFYVE16", "ZMYM3", "ZMYM4", "ZNF207", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AAMDC", "AAR2", "AARSD1", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD14B", "ACACA", "ACLY", "ACO1", "ACOT7", "ACSF2", "ACTR2", "AFDN", "AGL", "AHCY", "AHSA1", "AIP", "AK6", "AKAP17A", "AKAP9", "AKT1S1", "AKT2", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "AMMECR1", "AMPD2", "AP1B1", "AP1G1", "AP2A2", "AP3B1", "AP3D1", "APEX1", "APRT", "ARFGEF2", "ARRB1", "ASCC3", "ASNS", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP6V1D", "ATP6V1G1", "ATR", "AURKA", "BAG6", "BAIAP2", "BCOR", "BIRC6", "BLM", "BMS1", "BPTF", "BRAT1", "BTAF1", "BTF3", "BUB1", "BUD23", "C16orf58", "C8orf33", "CAD", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAPN2", "CAPZA2", "CARS", "CASP3", "CASP6", "CASP8", "CBL", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT3", "CD2AP", "CDC123", "CDC34", "CDC42", "CDC5L", "CDC6", "CDCA2", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CENPI", "CEP170", "CHAC2", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHEK2", "CHM", "CHMP7", "CHORDC1", "CHUK", "CIAO1", "CIP2A", "CKAP2", "CKAP5", "CKB", "CLIC1", "CLK3", "CLTC", "CLUH", "CMTR1", "CNOT1", "CNOT7", "COG2", "COG3", "COPA", "COPB1", "COPG1", "COPS3", "COPS5", "CORO1A", "COX15", "CRKL", "CSE1L", "CSNK2A1", "CTPS1", "CUL1", "CWF19L1", "CYFIP2", "DAD1", "DAXX", "DCAF7", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DDA1", "DDX1", "DDX20", "DDX24", "DDX28", "DDX46", "DDX55", "DDX6", "DHX16", "DHX29", "DHX34", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DIAPH1", "DICER1", "DIS3", "DLGAP5", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJC13", "DNAJC2", "DNAJC21", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL5", "DRG1", "DRG2", "DUS2", "DUSP12", "DUSP3", "DYNC1H1", "DYNC1LI2", "DYNLL1", "ECT2", "EDC3", "EDRF1", "EEF1A2", "EEF1G", "EEF2", "EI24", "EIF2A", "EIF2B2", "EIF2B5", "EIF2D", "EIF3A", "EIF3D", "EIF3G", "EIF4A2", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G3", "EIF5A", "EIF5B", "ELOA", "ELOC", "ELP1", "ELP3", "EML4", "EP400", "EPRS", "ERCC2", "ERCC6L", "ESPL1", "ESYT2", "EWSR1", "EXOC6", "EYA3", "FAH", "FAM120A", "FAM120B", "FAM208B", "FANCD2", "FANCI", "FARSA", "FARSB", "FASN", "FBXO7", "FHOD1", "FLAD1", "FLII", "FLYWCH2", "FMR1", "FN3KRP", "FOXK1", "FRYL", "FTSJ1", "FTSJ3", "GAK", "GALK1", "GALM", "GAPVD1", "GATA6", "GBF1", "GCN1", "GDE1", "GEMIN4", "GEMIN5", "GET4", "GFPT1", "GLMN", "GLOD4", "GLRX", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNE", "GOLT1B", "GPI", "GPKOW", "GSK3B", "GSTCD", "GSTM3", "GTF3C1", "GTF3C2", "GTPBP1", "GYS1", "H1FX", "HAT1", "HAUS6", "HBS1L", "HDGF", "HDGFL2", "HEATR3", "HECTD1", "HELLS", "HELZ", "HIKESHI", "HLCS", "HLTF", "HMCES", "HMGA1", "HMGB1", "HMGXB4", "HNRNPLL", "HNRNPUL1", "HPRT1", "HS1BP3", "HTT", "HUWE1", "IAH1", "IARS", "IGBP1", "IGHMBP2", "ILK", "IMPDH1", "IMPDH2", "INPPL1", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQSEC1", "IRF2BPL", "ISG20L2", "KDM1B", "KDM3B", "KDM5A", "KIAA0368", "KIAA0391", "KIAA1671", "KIF14", "KIF1B", "KIF20B", "KIF3A", "KNTC1", "KPNA3", "KPNA4", "LARP1", "LARP7", "LARS", "LCMT2", "LIG1", "LIG4", "LIMA1", "LLPH", "LNPK", "LRBA", "LTN1", "LUC7L2", "LZIC", "MACF1", "MAGED1", "MAGED2", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K2", "MAPK1", "MARK2", "MASTL", "MCM5", "MCM7", "MCMBP", "MCTS1", "MCUB", "MED1", "MED14", "MED16", "MED23", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL16", "MGA", "MID1", "MIF", "MKLN1", "MOCS1", "MON2", "MOV10", "MPG", "MSH3", "MSH6", "MSTO1", "MTA1", "MTAP", "MTOR", "MTR", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAF1", "NAGK", "NANS", "NARS", "NCAPD2", "NCAPD3", "NCAPH", "NCAPH2", "NCDN", "NCKAP1", "NECAP1", "NELFA", "NELFCD", "NELFE", "NEMF", "NEMP1", "NFKB2", "NFKBIE", "NIFK", "NMD3", "NME1", "NME2", "NMT1", "NOC3L", "NOL9", "NOM1", "NOP14", "NOP2", "NOP9", "NOSIP", "NPLOC4", "NPM3", "NR2F1", "NSUN5", "NSUN6", "NT5DC1", "NTMT1", "NTPCR", "NUBP2", "NUDT16", "NUDT16L1", "NUDT5", "NUP188", "OCRL", "ODR4", "OGFOD1", "OLA1", "ORC3", "ORC5", "OSBP", "OTUB1", "OTUD4", "OTUD7B", "PA2G4", "PAK1", "PANK4", "PAPOLA", "PARD3", "PARP1", "PATJ", "PATL1", "PCBD1", "PCID2", "PDS5A", "PDS5B", "PDXK", "PFKL", "PFKP", "PFN1", "PGM3", "PHF6", "PHF8", "PHKA1", "PI4KA", "PIAS1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PITPNA", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLPBP", "PMF1", "PMS1", "PNMA8A", "POLA1", "POLD1", "POLD2", "POLE", "POLR3A", "POLR3C", "POP1", "POP4", "PPIL4", "PPOX", "PPP1CA", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R1", "PPP6R1", "PPP6R3", "PPWD1", "PREP", "PRKAB1", "PRKACA", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSMA4", "PSMA5", "PSMB1", "PSMB2", "PSMB6", "PSMC5", "PSMD10", "PSMD3", "PSMD4", "PSME3", "PSME4", "PSMG1", "PSMG2", "PTDSS1", "PTGES3", "PTPA", "PTPN11", "PTPN13", "PUDP", "PYGB", "PYGL", "QARS", "QTRT2", "RAB13", "RAB3GAP1", "RACK1", "RANBP9", "RARS", "RAVER1", "RBM12B", "RBM34", "RBM42", "RDX", "RECQL", "REXO4", "RFC1", "RFK", "RHBDD2", "RHOA", "RIC8A", "RIOX2", "RNASEH2B", "RNF31", "RNGTT", "RNPEP", "ROCK2", "RPAP1", "RPL10", "RPL10A", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPP30", "RPP40", "RPRD1A", "RPS11", "RPS14", "RPS15", "RPS17", "RPS18", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS7", "RPS8", "RRM1", "RRP12", "RRP1B", "RTCB", "RTFDC1", "RUFY1", "S100A11", "SAMHD1", "SART1", "SART3", "SBF1", "SBNO1", "SDAD1", "SEC23A", "SEC31A", "SEPHS1", "SEPT2", "SETDB1", "SH3BGRL3", "SH3PXD2B", "SIN3B", "SIRT2", "SKIV2L", "SKP2", "SLC12A7", "SLC16A1", "SLC25A20", "SLFN11", "SLK", "SMAP1", "SMARCA4", "SMARCAD1", "SMC4", "SNRPA", "SNX17", "SNX5", "SORD", "SPAG9", "SPATA5L1", "SQSTM1", "SRM", "SRP19", "SRP68", "SRPK1", "SRPK2", "SSRP1", "STAT3", "STRAP", "STRIP1", "STX5", "SUPT16H", "SUPT6H", "TAF6L", "TAP1", "TARS", "TBC1D15", "TBC1D4", "TBCB", "TDRD7", "TFCP2", "TFIP11", "THOP1", "THUMPD3", "THYN1", "TIMMDC1", "TLN1", "TMEM165", "TNPO1", "TOMM34", "TOPBP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM25", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TROVE2", "TRRAP", "TSG101", "TSR1", "TTC1", "TTC37", "TTC38", "TTF2", "TTLL12", "TTPAL", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TXNL1", "TXNRD1", "UBA3", "UBE2M", "UBE3A", "UBE3C", "UBL7", "UBR4", "UBR5", "UBXN1", "UFSP2", "UGDH", "UMPS", "UPF2", "URGCP", "USP28", "USP34", "USP48", "USP8", "UTP20", "VAC14", "VARS1", "VIRMA", "VPS13D", "VPS29", "VPS45", "VPS51", "VPS53", "VRK1", "WAPL", "WARS", "WASHC4", "WASL", "WDCP", "WDR11", "WDR26", "WDR4", "WDR41", "WDR44", "WDR47", "WDR61", "XIAP", "XPNPEP1", "XPO1", "XPO5", "XPOT", "XRN1", "XRN2", "YBX1", "YIF1A", "YTHDC2", "ZC3H4", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZFP91", "ZFYVE16", "ZMYM4", "ZNF207", "ZNF281", "ZNF512B"]} \ No newline at end of file