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a34cac4 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.6579097035607058 3.3415005211621343 0.000833268600765 0.6925880537071551 0.3930250233608476 34 Q8NB78,Q32P28,P41229,P30519,Q8N543,O60427,O60568 7
Magnesium ion binding 0.4314445623480312 2.613051951252934 0.0089737660314532 0.9999971127209064 0.4385594406645747 75 Q969T7,P48735,Q9H773,P14618,O75874 5
Organic acid binding 0.5676737256002397 2.610427320284984 0.0090429185125355 0.9999973841886376 0.4385594406645747 33 P00374,Q05682,P13674,Q32P28,P48506,P41440,P05165,Q8N543,P11498,O60568 10
L ascorbic acid binding 0.8772465070258122 2.59645335535997 0.00941916936813 0.9999984716037176 0.4385594406645747 7 Q8N543,Q32P28,O60568 3
2 oxoglutarate dependent dioxygenase activity 0.6700638554772528 2.5661411578879907 0.010283696889823 0.9999995557015436 0.4385594406645747 19 Q8N543,Q32P28,O60568,P41229 4
Dioxygenase activity 0.6372497882325266 2.557039386670302 0.0105567263757351 0.9999996993064288 0.4385594406645747 22 Q32P28,P41229,Q6PCB5,Q8N543,O60568 5
Threonine type endopeptidase activity 0.7771519275823044 2.2751441344571464 0.0228972848523698 0.9999999999999942 0.4656411881055455 8 P49721,P28072,P28070 3
Iron ion binding 0.5609365001114618 2.202179468646116 0.0276526337475131 1.0 0.4656411881055455 26 Q8N543,Q32P28,O60568 3
Isocitrate dehydrogenase activity 0.940978521000142 2.186521392315003 0.0287774813459757 1.0 0.4656411881055455 4 P48735 1
Peptidyl proline dioxygenase activity 0.8542086908803248 2.09833505032777 0.0358755583464927 1.0 0.5076391506028717 5 Q8N543,Q32P28 2
Carboxylic acid binding 0.4825959198292273 2.0734652518694467 0.0381290017211162 1.0 0.5289464454448966 38 P00374,Q05682,Q8N543,P13674,Q32P28,P48506,P41440,P05165,P06737,P11498,O60568 11
Organic cation transmembrane transporter activity 0.8343544799959597 2.017608532531922 0.0436320475367515 1.0 0.5612667933136676 5 O43772 1
Nucleotidase activity 0.785277943726688 1.942856336134248 0.0520335188598581 1.0 0.6282251902925577 6 Q969T7 1
Threonine type peptidase activity 0.6680502897300805 1.9399225991303728 0.0523890971410048 1.0 0.6282251902925577 10 P49721,P28072,P28070 3
Vitamin binding 0.4541310298063554 1.886233246237722 0.059263530235194 1.0 0.6569540114740325 47 P00374,Q9Y697,P34897,Q96EY8,P13674,Q99707,Q32P28,P06737,P50747,P41440,P05165,Q8N543,P11498,O60568 14
Poly pyrimidine tract binding 0.5915052447233673 1.831840685234488 0.0669751597342818 1.0 0.6854674275579705 14 P11940,Q07666,O43347,P31943,P07910 5
Cytokine activity 0.788741545775862 1.8297052491224908 0.067294025570511 1.0 0.6854674275579705 5 P09429,P43490 2
Lipopolysaccharide binding 0.7041000092828382 1.823062878329444 0.0682938680969051 1.0 0.6854674275579705 7 P09429,Q8WTV0,P28070 3
Peptide alpha n acetyltransferase activity 0.7511444607036172 1.795966390692514 0.0724998624168726 1.0 0.6854674275579705 6 Q86UY6 1
Dystroglycan binding 0.7755332801588326 1.7746919375224046 0.0759487673014589 1.0 0.6854674275579705 5 Q15149,O75122 2
Fad binding 0.6349308097772269 1.7713518991252877 0.0765022020544252 1.0 0.6854674275579705 10 Q15392,Q8NB78 2
Fk506 binding 0.6917248518552632 1.7653227905968438 0.0775095313297447 1.0 0.6854674275579705 7 Q96AY3,P26885,Q9Y680,Q02790 4
Macrolide binding 0.6917248518552632 1.7653227905968438 0.0775095313297447 1.0 0.6854674275579705 7 Q96AY3,P26885,Q9Y680,Q02790 4
Growth factor activity 0.741695008332184 1.754956592618653 0.0792667328402227 1.0 0.6854674275579705 6 Q9UMX5,P55145,Q9Y3E1 3
Pentosyltransferase activity 0.5634718456668224 1.7545276594716532 0.0793401347365729 1.0 0.6854674275579705 15 P43490,Q13126,P00491 3
Dynein light intermediate chain binding 0.6877538873005657 1.7467325674469638 0.0806837383736871 1.0 0.6854674275579705 7 Q96ED9,Q8TD16 2
Procollagen proline dioxygenase activity 0.8244885767418338 1.729944279723327 0.0836402309840183 1.0 0.6854674275579705 4 Q32P28 1
N6 methyladenosine containing rna binding 0.7618522259537343 1.717444662434135 0.0858979571631948 1.0 0.6854674275579705 5 P07910,Q96MU7,Q7Z739 3
Carbohydrate binding 0.4310873889051984 1.7103711092694485 0.0871972699367029 1.0 0.6854674275579705 50 P13674,Q32P28,Q13438,P06737,P17858,O60762,P10253,Q8N4A0,Q8N543,P35613,O60568 11
Rna strand annealing activity 0.7584502849090433 1.7031693548570024 0.0885363798290179 1.0 0.6893771327453517 5 Q15056,P23588 2
Glycosyltransferase activity 0.4269922672972749 1.6856639264510094 0.0918605487302095 1.0 0.6950945264879493 51 P43490,P00491,Q6ZXV5,Q96L58,Q9NYU2,P15291,O60762,Q8N4A0,Q13126,O60568 10
Protein demethylase activity 0.6247833683250377 1.655850200426619 0.097752158697673 1.0 0.7137242025143464 9 Q8NB78 1
Collagen binding 0.6395947715294678 1.621289570364288 0.1049555507579182 1.0 0.7315867208002679 8 Q32P28 1
Nad binding 0.4724963673339002 1.6095698215663377 0.1074918008744374 1.0 0.7419556011577023 27 P48735 1
Chromo shadow domain binding 0.7316201961571953 1.5900638302073344 0.11182041790329 1.0 0.7425138254061278 5 Q6KC79,Q14739 2
Folic acid binding 0.7887724475685922 1.5865491984927305 0.1126147810042561 1.0 0.7425138254061278 4 P41440 1
Structural constituent of postsynapse 0.7884159772383552 1.5851116699890893 0.1129409645660222 1.0 0.7425138254061278 4 P07196 1
Tetrapyrrole binding 0.5164241261300183 1.5812337279192794 0.1138246062021606 1.0 0.7425138254061278 18 O00264,Q96EY8,O15173,Q7KZN9,P30519,Q8WUJ1 6
Protein transporter activity 0.5222600935779936 1.5787458822587068 0.114394356140308 1.0 0.7425138254061278 17 Q9NS69,Q9Y5J6,O60830 3
Structural constituent of cytoskeleton 0.422387116894993 1.5600548683698383 0.1187469155481664 1.0 0.7588070628900659 38 Q9UGJ1,P08670,Q01082,O15020,Q9Y5K6,Q15149,P26038,Q16352,Q16204,P07196 10
Mhc protein complex binding 0.6222028471550162 1.5358534843768277 0.1245743187056263 1.0 0.7692574949248353 8 P07900,Q9NUQ9,P05026,P14618 4
Monosaccharide binding 0.4560440884630772 1.5224197219601292 0.1279039462727174 1.0 0.7696006823022137 28 P13674,Q32P28,P17858,O60762,Q8N543,P35613,O60568 7
Glucosyltransferase activity 0.5733489275231678 1.5138731145851614 0.1300580241885822 1.0 0.7696006823022137 11 Q7Z4H8,Q9NYU2,O60568 3
Ionotropic glutamate receptor binding 0.6843600490980775 1.5033213319685437 0.1327562018077754 1.0 0.769877153926239 6 P41440,P27824 2
Supercoiled dna binding 0.7035237012021881 1.4707539054781915 0.1413576822669879 1.0 0.789156897251316 5 P09429 1
Single stranded dna exodeoxyribonuclease activity 0.7026992514480619 1.46724171890273 0.1423103117470947 1.0 0.789156897251316 5 Q9UQ84 1
Proline rich region binding 0.6278355724399297 1.4629526248654854 0.1434803426897182 1.0 0.789156897251316 7 P46934,Q6Y7W6,Q9UQB8,O00213,Q9UI14 5
Dolichyl phosphate mannose protein mannosyltransferase activity 0.9407449209932248 1.461814497922051 0.1437920501206635 1.0 0.789156897251316 2 Q6ZXV5 1
7sk snrna binding 0.7001844130744677 1.4565249636141424 0.1452475538138684 1.0 0.7902922816273878 5 Q7L2J0 1
Misfolded protein binding 0.5257086093689965 1.4535421883008213 0.1460732749981057 1.0 0.7902922816273878 14 Q9GZP9,P46379,P48723,Q13217,Q9UBS4 5
Phosphoserine residue binding 0.6992679772005252 1.4526183908847794 0.1463297369515022 1.0 0.7902922816273878 5 P46934 1
Exodeoxyribonuclease activity 0.5804639286944648 1.4297580091050506 0.1527864846805178 1.0 0.804347373089905 9 Q9UQ84 1
Minor groove of adenine thymine rich dna binding 0.7477812170616249 1.4206011173763782 0.1554327534762896 1.0 0.804347373089905 4 P17096 1
Histone h3 methyl lysine 4 demethylase activity 0.6808300982391382 1.3738951226652931 0.1694742440358931 1.0 0.8296279509661016 5 Q8NB78 1
14 3 3 protein binding 0.7359365522456284 1.3724645232047956 0.1699188756689067 1.0 0.8296279509661016 4 Q9UBF8 1
Biotin binding 0.6798678375888256 1.3697808678822416 0.1707553160607073 1.0 0.8302500221363545 5 P05165,P11498,P50747 3
Transferase activity transferring alkyl or aryl other than methyl groups 0.4426408877519584 1.3605880405321595 0.1736439131146228 1.0 0.8302500221363545 26 O15217 1
Nadph binding 0.6501688703505492 1.3514648849492314 0.1765465611140895 1.0 0.8303130067081286 6 P00374,Q9UBQ7,Q14739 3
Intermediate filament binding 0.7263525658481126 1.3334804041438155 0.1823742019923926 1.0 0.8313169010714722 4 P08670,P58107 2
Dna directed dna polymerase activity 0.58064584221035 1.3300111083909167 0.1835146113412824 1.0 0.8313169010714722 8 Q07864,Q9NR33 2
Hexosyltransferase activity 0.3958060363369661 1.329993408883792 0.1835204429472963 1.0 0.8313169010714722 38 Q6ZXV5,Q9NYU2,Q96L58,O60762,Q8N4A0,Q13126,O60568 7
Nadp binding 0.4708349250686815 1.329602666882506 0.1836492189832885 1.0 0.8313169010714722 19 O75874,P00374 2
Phosphatase regulator activity 0.4513497165425789 1.3273497509847867 0.1843930135680596 1.0 0.8313169010714722 22 P30154,Q6IN85,O95248,Q96QC0,Q9UQ13,Q01105 6
Endopeptidase activity 0.3397295138793489 1.3219515300579907 0.1861842915925957 1.0 0.8313169010714722 72 P28074,Q5JRX3,Q96K76,P28070,P60900,P49721,P20618,Q14790,P53634,Q9NZ08,P51784,Q96E52,Q9H300,P40818,Q4J6C6,Q9P0U3,Q92542,Q13867,Q9BYT8,Q16740,Q6P179,P28072 22
Mhc class ii protein complex binding 0.5960553202854925 1.310517035732243 0.1900209849808241 1.0 0.8313169010714722 7 P07900,P05026,P14618 3
Annealing activity 0.5463136226852007 1.309541446880227 0.1903510077365067 1.0 0.8313169010714722 10 Q15056,P23588,P28370 3
Folic acid transmembrane transporter activity 0.9001128668171487 1.3017351906590413 0.1930069253675523 1.0 0.835182872767849 2 P41440 1
Kinesin binding 0.5741240245469236 1.2975530576043095 0.194440961790475 1.0 0.8360514061748807 8 Q9NUL3,O60271,Q86UP2 3
Nuclear localization sequence binding 0.480953995732186 1.2905806490766538 0.196849129627548 1.0 0.837973501204996 16 Q7Z569 1
Single stranded rna binding 0.3889641492211463 1.2680759698875874 0.2047708220453357 1.0 0.8527999707853284 42 O60306,Q9Y606,P11940,Q07666,P51114,O14979,O43347,Q15056,P31943,P23588,Q96KR1,P52597,P07910 13
Galactosyltransferase activity 0.6285730686119976 1.2551613475417045 0.2094201938921505 1.0 0.8545337027648193 6 Q96L58,O60568 2
Demethylase activity 0.5139877763256149 1.2538110625664671 0.2099106872873792 1.0 0.8545337027648193 12 Q8NB78 1
Ubiquitin binding 0.4004539122813718 1.24293987180223 0.2138899915068031 1.0 0.8545337027648193 32 P46934,Q9UNZ2,Q9Y3I1,Q8TAF3,Q9H1I8,Q5TDH0,Q9H0E2,Q9UK41,O14964,P37198,P04792,O95071,Q96CS3,Q6ZVM7,Q13501 15
Phosphatase activity 0.371245168205224 1.2358905622038714 0.2164992456200178 1.0 0.8545337027648193 57 Q969T7,Q9BRF8,Q9NPH0,Q9H857 4
Dna polymerase activity 0.531932094975609 1.233695913828886 0.2173162371285899 1.0 0.8545337027648193 10 Q07864,Q9NR33 2
Udp glucosyltransferase activity 0.5788224942802194 1.2275669271707297 0.2196095834660614 1.0 0.8545337027648193 7 Q7Z4H8,Q9NYU2 2
Protein kinase a regulatory subunit binding 0.5306625391999237 1.2269975525107506 0.2198235108172397 1.0 0.8545337027648193 10 Q9ULX6,P15311,Q99996,O43823,Q96M27 5
Protein phosphatase regulator activity 0.4466412681380212 1.2100953376451562 0.2262423120073098 1.0 0.865223977000928 20 P30154,Q6IN85,Q9UQ13,Q96QC0,Q01105 5
Cytoskeletal anchor activity 0.57473393948499 1.2078747466285686 0.2270954446094544 1.0 0.8661456984430674 7 Q8TD16 1
Structural constituent of synapse 0.5715041242479362 1.192318031575346 0.2331365668524485 1.0 0.8737024559069172 7 Q8IUD2,P07196,O15020,Q16352 4
High density lipoprotein particle binding 0.869624602353082 1.19156537521254 0.2334317083550832 1.0 0.8737024559069172 3 Q9BQE5 1
S100 protein binding 0.5526298445432776 1.1904525005574107 0.2338685886574256 1.0 0.8737024559069172 8 Q09666,P15311,Q9HB71,P31949,P46940 5
Sequence specific mrna binding 0.5700973758168872 1.1855424118810376 0.2358030561376205 1.0 0.8737024559069172 7 P00374 1
Microtubule minus end binding 0.5699299767047192 1.1847361433510086 0.2361217872869823 1.0 0.8737024559069172 7 Q9UGJ1,Q9UPN3 2
Volume sensitive anion channel activity 0.6892913381367627 1.182690729911992 0.2369317394484205 1.0 0.8737024559069172 4 Q8IWT6,P51790 2
Tropomyosin binding 0.8670618120237104 1.182257092023759 0.2371037053485909 1.0 0.8737024559069172 3 Q9NYL9,Q05682 2
Phosphatidylinositol kinase activity 0.6327997730171606 1.1682541179222528 0.2427042767937577 1.0 0.8740807246444168 5 Q13315,Q9UBF8 2
C2h2 zinc finger domain binding 0.685343525936881 1.166648623064733 0.243352298793235 1.0 0.8740807246444168 4 Q96KQ7,Q9UQ35 2
Phosphatidylinositol 3 4 5 trisphosphate binding 0.5181255220786807 1.1608546524326986 0.2457010130095458 1.0 0.8744768188190047 10 Q13576,P46940 2
5 3 exonuclease activity 0.5278321115375327 1.1583791197723148 0.246709356285574 1.0 0.8744768188190047 9 Q9UQ84 1
Vascular endothelial growth factor receptor binding 0.861738148984198 1.1514637731941026 0.249541490657501 1.0 0.8744768188190047 2 Q9Y5K6 1
Udp glycosyltransferase activity 0.4245445118025939 1.1429669151600963 0.2530523278569223 1.0 0.8744768188190047 22 Q9NYU2,Q96L58,O60568,Q8N4A0 4
Dna secondary structure binding 0.5038990168571289 1.1401741640758023 0.2542137488612486 1.0 0.8744768188190047 11 O15347,P09429,Q14103,P17096 4
Signal sequence binding 0.3965220007930077 1.1383190862335733 0.2549872670551252 1.0 0.8744768188190047 30 Q7Z569,P24390 2
Gtp dependent protein binding 0.5137947649070044 1.1380171554378402 0.2551133188824996 1.0 0.8744768188190047 10 O00429,Q15075,Q9BZG1 3
Guanylate kinase activity 0.6771783261809001 1.1334973826879464 0.2570054396951233 1.0 0.8744768188190047 4 Q9UDY2 1
Nucleoside monophosphate kinase activity 0.5213415375416905 1.1248738327932497 0.2606425018370748 1.0 0.8754437975432805 9 P23919,Q14168,P30085,P00568,Q9UDY2 5
Phosphoric ester hydrolase activity 0.3261634673433369 1.1181980627935304 0.2634824114875211 1.0 0.8754437975432805 71 Q969T7 1
Monooxygenase activity 0.5357522963186818 1.1063676585908298 0.2685674179192117 1.0 0.8817236574377831 8 Q9BU89,P30519 2
Glutamate receptor binding 0.5317762309024825 1.0865808881499623 0.2772220751593064 1.0 0.8876274104826525 8 P41440,P27824 2
General transcription initiation factor activity 0.5293068058068701 1.0742985934295848 0.2826888752583416 1.0 0.8897321705291313 8 P29083,P17480 2
Thioredoxin disulfide reductase activity 0.8417042889390445 1.0737077343050463 0.2829536938078509 1.0 0.8897321705291313 2 Q16881 1
Protease binding 0.3618738549472148 1.053366965037393 0.29217283853691 1.0 0.8973951768892041 35 P41440,Q9GZP9,Q13438 3
Ligase activity forming carbon carbon bonds 0.5426051537526508 1.053278788985253 0.2922132373139907 1.0 0.8973951768892041 7 P05165,P11498 2
Histone h3 tri di monomethyl lysine 4 demethylase activity 0.8323927765236898 1.0377955523685545 0.2993652479153099 1.0 0.9070161162584373 2 P41229 1
Rna polymerase ii ctd heptapeptide repeat kinase activity 0.5384373216168309 1.0332790484599566 0.3014733291821647 1.0 0.9070161162584373 7 O60885,Q9NYV4,Q00534 3
Calmodulin binding 0.3589776829319943 1.017721583552253 0.3088102870766143 1.0 0.9137900451930476 48 Q05682,Q13425,Q15075,Q01082,P35579,Q86VI3,Q7Z406,Q9UII2,Q15051,Q13576,O43815,Q01844,P35580,P46940 14
Rna polymerase ii c terminal domain binding 0.6481814922475014 1.0162504811168345 0.3095101228585077 1.0 0.9137900451930476 4 O60885,Q92541 2
Atp dependent peptidase activity 0.5966669330475464 1.0140693535697003 0.3105496602424562 1.0 0.9137900451930476 5 P36776,Q16740,Q96TA2 3
Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters 0.8222347629796786 0.9988152331655163 0.3178842052891273 1.0 0.9229828011894178 2 Q96QE5 1
Atp dependent chromatin remodeler activity 0.6397803060261147 0.9824832362410296 0.3258618376630704 1.0 0.9253973519016894 4 P28370,Q9HCK8 2
Death receptor binding 0.810974120967677 0.9802706872581302 0.3269525200093266 1.0 0.9253973519016894 3 Q13546 1
Notch binding 0.636390729750329 0.9688928917898908 0.33259863239206 1.0 0.9253973519016894 4 Q2M2I8 1
Phosphatidylinositol 3 kinase activity 0.813205417607224 0.96435991295639 0.3348655127458546 1.0 0.9253973519016894 2 Q13315 1
1 phosphatidylinositol 3 kinase activity 0.813205417607224 0.96435991295639 0.3348655127458546 1.0 0.9253973519016894 2 Q13315 1
Vitamin transmembrane transporter activity 0.523487643854007 0.9617432856947072 0.3361785731762901 1.0 0.9253973519016894 7 P41440,P33527 2
Rrna adenine methyltransferase activity 0.8057272491289682 0.9616090728535952 0.3362460122795498 1.0 0.9253973519016894 3 Q86W50 1
Mrna methyltransferase activity 0.5624302763387119 0.960865819746718 0.3366196387564588 1.0 0.9253973519016894 6 Q86W50 1
Signaling receptor regulator activity 0.4127965873463906 0.955302128209302 0.3394249315729314 1.0 0.9253973519016894 19 P43490,Q9UMX5,Q86XI2,P09429,Q9Y3E1 5
Snap receptor activity 0.4247364323294857 0.947437182419839 0.3434160517438762 1.0 0.9253973519016894 16 O95721,Q86Y82,O43752 3
Mhc class ib protein binding 0.808126410835208 0.9450670049090776 0.3446246690232812 1.0 0.9253973519016894 2 Q9NUQ9 1
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.4571270887281408 0.941275471798644 0.3465637090920581 1.0 0.9267582819732912 12 Q8N4Q0 1
Myosin binding 0.4660534215171893 0.9372170366480564 0.3486469280468833 1.0 0.9290685559064782 11 Q05682,Q86VI3 2
Anaphase promoting complex binding 0.6253759634233462 0.92488189100134 0.355027347298865 1.0 0.9372457022908468 4 Q16763 1
Apolipoprotein binding 0.6243144219089758 0.9206537483835292 0.3572312309750396 1.0 0.9387146811557048 4 Q8WTV0 1
Peptide receptor activity 0.801354401805865 0.9194500434972128 0.3578602241319135 1.0 0.9387146811557048 2 Q99720 1
Small ribosomal subunit rrna binding 0.6216723359375551 0.9101413085621942 0.3627479918189094 1.0 0.9438645344098489 4 Q14011 1
Aminopeptidase activity 0.4209152930370512 0.90205612106526 0.3670270562841864 1.0 0.949116320783779 15 Q9NQW7,Q13867,Q9NZ08,P50579 4
Protein lipid complex binding 0.5699084501954039 0.901028881556937 0.3675729638088416 1.0 0.949116320783779 5 Q9BQE5 1
Acid amino acid ligase activity 0.5461047033410833 0.8890825359257272 0.3739587239312993 1.0 0.958617754807324 6 P48506,P48507,Q14166 3
Phosphatase activator activity 0.6117619542147258 0.8708600345417233 0.3838305807574853 1.0 0.9635378896404464 4 Q13362,Q6IN85 2
Protein phosphatase activator activity 0.6117619542147258 0.8708600345417233 0.3838305807574853 1.0 0.9635378896404464 4 Q13362,Q6IN85 2
Histone deacetylase binding 0.3404424876192871 0.8685039785575176 0.3851184952306379 1.0 0.9635378896404464 36 P07900,Q4G0X4,Q14103,Q9ULX6,P09874,Q6KC79,Q14839,Q9UHI6,P23246,Q9BTC8,Q12834,O43823 12
Translation repressor activity 0.4711885906657328 0.8678671212256623 0.3854670799264734 1.0 0.9635378896404464 9 P00374,Q14011 2
Ubiquitin like modifier activating enzyme activity 0.4872682604061176 0.8667188012755896 0.3860961013612247 1.0 0.9635378896404464 8 O95352 1
Gtpase inhibitor activity 0.55901203590224 0.8554562015832856 0.3922986415313112 1.0 0.9704590520398696 5 Q13576,P46940 2
Cobalamin binding 0.7715061229505094 0.8413502846964459 0.4001517280328146 1.0 0.9725021438363 3 Q96EY8 1
Metalloaminopeptidase activity 0.438471139894989 0.8403991441173988 0.4006846288738961 1.0 0.9725021438363 12 Q9NQW7,P50579,Q9NZ08 3
Signaling receptor complex adaptor activity 0.5310521215386415 0.8235000137810276 0.4102237093465235 1.0 0.9916351349804924 6 P46108,O60271,Q9UN86 3
Ubiquitin like protein transferase activity 0.2935435148792564 0.8227149735192285 0.4106700983028752 1.0 0.9916351349804924 78 P46934,Q16763,Q9Y3I1,O75928,Q7Z569,Q15386,O95155,P19474,Q9UII4,Q14527,O95071,P98170,Q93034 13
Flavin adenine dinucleotide binding 0.3498810291989346 0.8128197863573088 0.4163213894785893 1.0 0.9994079072434616 31 Q15392,Q8NB78,Q16881 3
Carbohydrate derivative transmembrane transporter activity 0.4271174319477903 0.7798021018291881 0.4355073690156146 1.0 1.0 12 P41440 1
Rna methyltransferase activity 0.3662912750511307 0.7770621529343287 0.4371221018322 1.0 1.0 24 Q08J23,Q96RS0,Q13395,Q86W50,Q8IY81,Q7L2J0,Q9UNQ2 7
1 phosphatidylinositol binding 0.5181492937401638 0.7678773566259752 0.4425600510655059 1.0 1.0 6 Q15075 1
Protein kinase a binding 0.3786172290186965 0.7678627749768226 0.4425687149247124 1.0 1.0 20 P49840,Q9ULX6,P23396,P15311,Q99996,O43823,P35241,Q96M27 8
Map kinase scaffold activity 0.5841759446780821 0.7630388344289151 0.4454402360947616 1.0 1.0 4 P46940 1
Ligase activity forming carbon nitrogen bonds 0.3658171854073226 0.759481733189936 0.4475644371767808 1.0 1.0 23 Q05682,P17812,P48507,P48637,P48506,Q9NRF8,P50747,Q14166,O15067,O75879 10
Translation initiation factor activity 0.3274000723350413 0.7559597117996094 0.4496733512631479 1.0 1.0 37 P56537,O60573,P05198,P55010,Q15056,P23588,P06730,Q04637,O15372,Q92905,O75822,P41214,Q14152 13
Oxidoreductase activity acting on ch oh group of donors 0.3236791470464786 0.7557572119978114 0.4497947750196347 1.0 1.0 56 Q8N4Q0,P48735 2
Cardiolipin binding 0.7570541760722345 0.7555652032505514 0.4499099252522047 1.0 1.0 2 Q9UJZ1 1
Intramembrane lipid transporter activity 0.534431570668217 0.7540226743532779 0.4508356066840078 1.0 1.0 5 Q9NV96 1
Atpase coupled intramembrane lipid transporter activity 0.534431570668217 0.7540226743532779 0.4508356066840078 1.0 1.0 5 Q9NV96 1
Solute proton antiporter activity 0.7525395033860045 0.7392944725271068 0.4597282050160063 1.0 1.0 2 O95202 1
L aspartate transmembrane transporter activity 0.577730103047169 0.7382348967206954 0.4603717203918682 1.0 1.0 4 Q9H936,Q15758 2
Acidic amino acid transmembrane transporter activity 0.577730103047169 0.7382348967206954 0.4603717203918682 1.0 1.0 4 Q9H936,Q15758 2
Dna polymerase binding 0.434510587488899 0.7266762787079277 0.4674242882109372 1.0 1.0 10 P07900,P36776,P09429,P08238 4
Peptidyl proline 4 dioxygenase activity 0.7358171041490227 0.7194613464359798 0.4718567102201279 1.0 1.0 3 O15460,P13674 2
Procollagen proline 4 dioxygenase activity 0.7358171041490227 0.7194613464359798 0.4718567102201279 1.0 1.0 3 O15460,P13674 2
1 4 alpha oligoglucan phosphorylase activity 0.7335369880956081 0.7118275440209398 0.4765715741116667 1.0 1.0 3 Q13126 1
Deoxyribonuclease activity 0.369340693313291 0.7097818899605092 0.4778394011740117 1.0 1.0 20 Q96QE5,Q9UQ84,Q07864 3
Hsp70 protein binding 0.3802178482037895 0.703927069174901 0.4814781929354026 1.0 1.0 17 Q9NZJ4,P25685,Q8IXB1,P46379,P23396,Q96EY1,Q99543,Q53FT3,Q9NUL3 9
Manganese ion binding 0.3565264072060788 0.686659504273369 0.4922973215227397 1.0 1.0 22 P15291,Q8N4A0 2
Cullin family protein binding 0.4641977420610175 0.6841943357951891 0.4938524585078299 1.0 1.0 7 Q4G0X4 1
Dna binding bending 0.4975116961299698 0.6803688951629137 0.4962709110219723 1.0 1.0 6 P09429 1
3 5 dna helicase activity 0.4334552021249605 0.6799759697462388 0.4965196766472788 1.0 1.0 9 P49736,P19447 2
Rna stem loop binding 0.4316630828827931 0.6712531115952702 0.5020592992388329 1.0 1.0 9 Q86W50 1
Histone methyltransferase activity h3 k36 specific 0.5562819153775325 0.657023792932231 0.5111656178079718 1.0 1.0 4 Q86TU7 1
Chemokine binding 0.7168915920521923 0.6567529088645003 0.5113398081163498 1.0 1.0 3 P09429 1
Ankyrin binding 0.7162917197384393 0.6547907773671502 0.5126024693474367 1.0 1.0 3 Q01082 1
Nuclear import signal receptor activity 0.3852355580493693 0.6464491324352937 0.5179885299352267 1.0 1.0 14 Q9Y5L0,Q53FT3 2
Solute cation antiporter activity 0.7136856163600587 0.6462857412940999 0.5180943203777986 1.0 1.0 3 O95202 1
Microtubule motor activity 0.3494394418715709 0.641458306596839 0.5212249611253603 1.0 1.0 22 Q8NCM8,Q96Q89,P52732,Q15058,Q2M1P5,Q9NQT8 6
Keratin filament binding 0.7109886028736417 0.6375175909239101 0.5237877554500834 1.0 1.0 3 P08670 1
Calcium ion binding 0.2987186503313459 0.6310521999866848 0.5280063938513211 1.0 1.0 93 Q9Y680,P19022,O43149,O43852,Q14126,Q9UBC2,O60245,O95302,Q9NWM8,P46940,Q14257,P27824,Q03001,Q9H4M9,P41208,Q96AY3,P80303,Q9UPN3,O75071,P14314,Q14574,P42566,P12429 23
Phosphotransferase activity phosphate group as acceptor 0.3980068323843431 0.6284122007890072 0.5297339465177306 1.0 1.0 12 Q14168,Q9UDY2 2
Amide transmembrane transporter activity 0.4500387672741724 0.6203760750932819 0.5350102200295781 1.0 1.0 7 P41440,P33527 2
O methyltransferase activity 0.4355816147660841 0.6201974991785179 0.5351277677756969 1.0 1.0 8 Q7L2J0 1
Rna polymerase ii general transcription initiation factor activity 0.4497364015267542 0.6190278361743831 0.5358980212429354 1.0 1.0 7 P29083 1
5s rrna binding 0.4816008314658708 0.6144353708770486 0.5389276683582089 1.0 1.0 6 P62913,Q15050,P46777 3
Histone methyltransferase activity h3 k9 specific 0.7155756207674946 0.6099338236202726 0.5419056456276872 1.0 1.0 2 Q96KQ7 1
H4 histone acetyltransferase activity 0.5406511099847275 0.5993400159516437 0.5489461684119321 1.0 1.0 4 Q86UY6 1
Amino acid binding 0.3839701917589166 0.5965247295638982 0.5508247384450182 1.0 1.0 13 P48506,Q05682 2
Sh3 domain binding 0.3397341116829497 0.5908294017955978 0.5546347327407595 1.0 1.0 23 Q07666,P50570,Q9Y5K6,P46108,Q16204,P40818,Q96PU8,P42566 8
Cytokine receptor binding 0.3357849618891984 0.5902886147632527 0.5549971710266852 1.0 1.0 25 Q9NZ08,Q9H2J4,Q9Y5K6,P30046,P48681,Q13546 6
Microtubule binding 0.2989240432958199 0.5873051828460344 0.5569987608951288 1.0 1.0 96 Q9BSJ2,P50570,P78559,Q9UBK9,P49454,Q13586,Q9Y3E1,Q96ED9,Q9UGJ1,Q96Q89,Q9C0F1,Q14203,Q66K74,Q03001,P52732,P41208,Q2M1P5,Q9UPN3,O00429,Q86VS8,Q8NBT2,O75122,Q6NUK4,P23396,P15311,Q9NQT8 26
Catalytic activity acting on dna 0.2902166537012904 0.5837982476581733 0.559356057356581 1.0 1.0 90 Q96QE5,Q9UNY4,Q9UQ84,P09884,Q86WJ1,Q92900,Q14527,Q66K74,Q9HCK8,Q14839,P41440,P19447,P49736,Q07864,Q9Y620,P28370,P23396,P33991,Q9NR33 19
Four way junction dna binding 0.4729285559304862 0.5791738075425437 0.5624719022988889 1.0 1.0 6 O15347,P43246,P09429 3
Minus end directed microtubule motor activity 0.7056997742663549 0.5767066114371524 0.5641376654399453 1.0 1.0 2 Q8NCM8 1
Modified amino acid transmembrane transporter activity 0.5342073707431587 0.5759858962850194 0.5646247146262866 1.0 1.0 4 P41440,P33527 2
Cytoskeletal motor activity 0.3061614489315075 0.5743180975781748 0.5657525647523842 1.0 1.0 34 Q8NCM8,Q96Q89,P52732,P35579,Q15058,Q7Z406,Q2M1P5,P35580,Q9NQT8,O60333 10
Protein phosphatase 1 binding 0.532176875608694 0.5686823318398516 0.5695717401561051 1.0 1.0 4 Q9UQ13 1
Pseudouridine synthase activity 0.4875497387010669 0.5682969514243943 0.569833348717316 1.0 1.0 5 Q96PZ0 1
Phospholipid transporter activity 0.4090930307845317 0.5635336919963123 0.5730715244209266 1.0 1.0 9 Q9NV96 1
Microtubule plus end binding 0.3927982553215783 0.5614011172072052 0.5745241225962638 1.0 1.0 11 Q03001,Q14203,O75122 3
N acyltransferase activity 0.3292508989290373 0.5366289262997948 0.5915239591207588 1.0 1.0 24 Q86UY6,Q969G3,Q8N5B7,O60551,Q6N069 5
Nadplus kinase activity 0.6775047450638652 0.5318031009207406 0.5948623748520327 1.0 1.0 3 Q4G0N4 1
Ribosome binding 0.3021979195423535 0.5291058589977381 0.5967320172710049 1.0 1.0 44 P56537,P46379,O95202,Q99543,Q96A33,Q8WWC4,Q9NUL3,Q07021,Q7Z739,Q6N069 10
Rna polymerase i transcription regulatory region sequence specific dna binding 0.6910270880360987 0.5285486220509189 0.5971186093433936 1.0 1.0 2 P17480 1
Mannosyltransferase activity 0.4748593688113863 0.5204348678971054 0.6027605129583338 1.0 1.0 5 Q6ZXV5 1
Rna 7 methylguanosine cap binding 0.4134184125596768 0.5199877284338671 0.6030721282190561 1.0 1.0 8 P52298,P06730 2
Ubiquitin specific protease binding 0.3907708674315117 0.5142600414742041 0.6070701947101815 1.0 1.0 10 Q9GZP9 1
Nucleoside diphosphate kinase activity 0.4700836060499066 0.5027526198254427 0.6151382090734394 1.0 1.0 5 Q13232,P23919,P00568 3
R smad binding 0.513451055410575 0.5026909297942467 0.6151815876809341 1.0 1.0 4 P09874 1
Ribosomal large subunit binding 0.3840956942760207 0.4835271228267809 0.6287215062919511 1.0 1.0 10 O60524,Q9H6R0 2
Rage receptor binding 0.6597606216685826 0.4784664520487033 0.6323182464073442 1.0 1.0 3 P09429 1
Hydroxymethyl formyl and related transferase activity 0.5001566132654927 0.4574886679400725 0.6473198455778941 1.0 1.0 4 P34897,P31939 2
Modified amino acid binding 0.3141106896610457 0.455992704491953 0.6483952244003839 1.0 1.0 25 P41440,P00374,Q08431,Q8WTV0 4
Cytokine binding 0.4560901610060467 0.4520865885887289 0.6512066049106542 1.0 1.0 5 P09429,P06756 2
Oxidoreductase activity acting on the ch ch group of donors 0.3005145036236617 0.4447050417643536 0.6565329253113728 1.0 1.0 30 Q15392,Q8N4Q0 2
Ubiquitin like protein binding 0.2865463411589082 0.4407451309825437 0.6593975199883775 1.0 1.0 38 P46934,Q9UNZ2,Q9Y3I1,Q8TAF3,Q9H1I8,Q5TDH0,Q9H0E2,Q99816,Q9UK41,O14964,P37198,P04792,O95071,Q96CS3,Q6ZVM7,Q13501 16
Eukaryotic initiation factor 4e binding 0.6443691786621499 0.4339424766262124 0.6643302133966973 1.0 1.0 3 Q04637,Q6PKG0 2
Protein phosphorylated amino acid binding 0.3339292706084542 0.4211325674766206 0.6736582813760614 1.0 1.0 15 P46934,Q92541 2
Ubiquitin like protein ligase activity 0.2852617407743616 0.4206142608002174 0.6740367785208061 1.0 1.0 56 P46934,Q15386,O75928,Q7Z569,O95155,P19474,Q14527,O95071,P98170 9
Organic anion transmembrane transporter activity 0.2872534308092807 0.4191411674212362 0.6751129657535067 1.0 1.0 33 Q9H2D1,Q96NB2,Q9Y619,P33527,Q8IWT6,P41440,P53985 7
Cyclin dependent protein kinase activity 0.3871746818232493 0.4078371805714187 0.6833932149739903 1.0 1.0 8 Q9NYV4,Q00534,P21127 3
Mrna 5 utr binding 0.3139936647208529 0.407525502645597 0.6836220673092637 1.0 1.0 21 P34897,P46777,O60506,P19338,P35580,Q9Y6M1 6
Poly a binding 0.3496603465349766 0.3970540080597354 0.6913276343378778 1.0 1.0 12 P11940,Q07666,O14979 3
Nucleobase containing compound kinase activity 0.3213143140658624 0.3955387901921184 0.6924453001166158 1.0 1.0 18 Q13232,P23919,Q00013,Q14168,Q5KU26,P30085,O94992,P00568,Q9BZX2,Q9UDY2 10
Lipid transporter activity 0.2975497462666826 0.3953861460241606 0.6925579317799215 1.0 1.0 28 Q9Y255,Q96AA3,Q9NV96,P33527,P17900 5
Deaminase activity 0.3820166239601719 0.3868017038054286 0.6989030157685558 1.0 1.0 8 P32321,Q9NRW3 2
Molecular function inhibitor activity 0.3543401902297287 0.384679349989292 0.7004749964015471 1.0 1.0 11 Q9UII2 1
Rna cap binding 0.3543229784138024 0.3846051776526277 0.7005299574690516 1.0 1.0 11 P52298,P06730 2
Signaling adaptor activity 0.3214521175131725 0.3828419473185428 0.7018369571551979 1.0 1.0 17 Q07666,P46108,Q6SZW1,O60271,Q9UN86,P46940 6
Cytoskeleton nuclear membrane anchor activity 0.476947104674492 0.3823720317127584 0.702185432576885 1.0 1.0 4 Q9UH99 1
Mrna 3 utr binding 0.2822482088423328 0.3779161915603707 0.7054928537910465 1.0 1.0 47 P35637,P11940,Q01085,Q92804,Q14103,Q14011,P51114,O75150,Q13310,Q5VTR2,P22626,P07910,Q9Y6M1 13
Plus end directed microtubule motor activity 0.379611703769643 0.3771203173432887 0.7060841929720554 1.0 1.0 8 Q15058,Q96Q89,P52732 3
Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.2986723398688009 0.3674267096883639 0.7133007513038292 1.0 1.0 25 Q07864,Q9HBH5,Q9UQ84,Q9H0D6 4
Ubiquitin ubiquitin ligase activity 0.3890474938845778 0.3654015139580678 0.7148117112904626 1.0 1.0 7 O95155 1
Growth factor receptor binding 0.3193449673505626 0.3611496408950806 0.717987585790393 1.0 1.0 16 Q92600,Q9NZ08,Q92542,Q9H2J4,Q9Y5K6,O60749,P62993 7
Neutral amino acid transmembrane transporter activity 0.4274857009442957 0.3546051867869339 0.7228853898796417 1.0 1.0 5 Q96NB2 1
Atp dependent activity acting on dna 0.2746330872590786 0.3504636389341717 0.7259907738224158 1.0 1.0 58 Q9UNY4,O60264,Q92878,O14981,P52701,Q86WJ1,P49959,Q14527,Q92900,Q9HCK8,Q14839,P46063,P13984,P43246,P41440,P19447,P51532,P51530,P49736,P33993,Q9UQE7,Q9Y620,Q13283,P28370,O00571,P33991 26
Cis trans isomerase activity 0.2848906471051465 0.3504432357322409 0.7260060836000815 1.0 1.0 30 Q8WUA2,Q9Y680,O95302,Q9NWM8,Q96AY3,P26885,P45877 7
Ankyrin repeat binding 0.6286681715575477 0.3433447431022268 0.7313391241565754 1.0 1.0 2 Q9C0C2 1
Atpase activator activity 0.3306012371004541 0.3416705673917584 0.7325988243215187 1.0 1.0 13 P25685,Q96DA6,Q96KC8,Q8IXB1,P05026,Q99543,Q8NFQ8 7
Protein membrane adaptor activity 0.3506519005244963 0.3388968020085348 0.734687473669565 1.0 1.0 10 P35579,Q9UH99,P12270,Q8NF91 4
Cyclin binding 0.3234098146353815 0.3387340630623695 0.7348100774743789 1.0 1.0 14 Q9NYV4,Q9UII4,O14976,Q00534 4
Metallopeptidase activity 0.2749298669377676 0.3347938771867036 0.7377805795477927 1.0 1.0 44 Q9NXS2,Q9NZ08,Q96E52,P50579,Q9BYT8,O15372,Q9HD42 7
Exonuclease activity 0.2678509517300294 0.3324163024117952 0.739574930241673 1.0 1.0 36 Q9BQ61,Q9UQ84 2
Glucosidase activity 0.4203605867373573 0.3317685360717659 0.7400640444364153 1.0 1.0 5 P10253 1
Cyclin dependent protein serine threonine kinase activator activity 0.6202031602708722 0.3210415637544135 0.7481788933475724 1.0 1.0 2 P14635 1
Protein macromolecule adaptor activity 0.2769186464011367 0.3144868555610485 0.7531512981713653 1.0 1.0 100 O14653,O15498,P78559,Q9BXS5,Q9UH99,P45973,P35579,P53680,P46108,O43752,P07196,P63010,P62993,Q9UDY2,Q93034,Q9Y3I1,Q02790,O00161,Q6SZW1,O60271,P46940,O95721,Q07666,Q86Y82,Q8TD16,Q9UNK0,Q9UQB8,Q8NF91,P05026,P12270,Q9UN86,Q13428,Q92542,Q13617,P37198,Q9UHI6,Q96CW1 37
Translation repressor activity mrna regulatory element binding 0.4009665502602959 0.3127304161905447 0.7544854850386591 1.0 1.0 6 P00374 1
Phosphatase inhibitor activity 0.3745376358637254 0.3112919884076294 0.7555786572706231 1.0 1.0 7 Q96QC0 1
Ligase activity forming carbon sulfur bonds 0.3038489643041969 0.3105513113932334 0.7561417459583524 1.0 1.0 18 O95352 1
Glucocorticoid receptor binding 0.6142776523701924 0.305881922758213 0.7596945502519628 1.0 1.0 2 Q02790 1
Poly purine tract binding 0.3037172833268554 0.2899071394708044 0.7718872795696168 1.0 1.0 16 P11940,Q07666,O14979 3
Carbon nitrogen ligase activity with glutamine as amido n donor 0.3562464833291596 0.2876505261884222 0.7736142643518447 1.0 1.0 8 O75879 1
Sodium channel regulator activity 0.4050761404782379 0.2849624269142606 0.7756729279345806 1.0 1.0 5 P46934 1
Serine transmembrane transporter activity 0.4431796538950358 0.2832281447854793 0.7770019548548717 1.0 1.0 4 Q96NB2 1
Phosphatidylethanolamine binding 0.4037497973638162 0.2810479486001094 0.7786736236272838 1.0 1.0 5 A0FGR8,Q08431,P50995 3
Organophosphate ester transmembrane transporter activity 0.3024937258363824 0.2768827281980541 0.7818701552132512 1.0 1.0 15 Q8IWT6,P41440 2
Nucleotide transmembrane transporter activity 0.3024937258363824 0.2768827281980541 0.7818701552132512 1.0 1.0 15 Q8IWT6,P41440 2
Microfilament motor activity 0.3343786855368337 0.2753215572549685 0.7830692039237725 1.0 1.0 10 Q7Z406,P35580 2
Clathrin binding 0.2836468564794585 0.2699342093288763 0.7872108684827175 1.0 1.0 22 Q07954,Q9BXS5,P09496,Q9H3U1,P53680,Q5VW38,O00443,Q6ZVM7,Q96CW1,O14976 10
Proteoglycan binding 0.4369904683962284 0.2665302859641643 0.789830837853402 1.0 1.0 4 O94813 1
Retinoid x receptor binding 0.5765303295512794 0.2609281117322241 0.7941479455508784 1.0 1.0 3 P17096 1
Cyclin dependent protein serine threonine kinase regulator activity 0.3461380378992335 0.2517876546862699 0.8012052001018672 1.0 1.0 8 O95067,P49736,O94992 3
Adp binding 0.2778913618810487 0.247817397587033 0.8042756934046429 1.0 1.0 23 P35580,P48506,Q8NI60 3
Rna polymerase iii transcription regulatory region sequence specific dna binding 0.570317279225815 0.2472413468267205 0.8047214482031388 1.0 1.0 3 P30044 1
Opsonin binding 0.4294636777193824 0.2468885260126691 0.8049944964260314 1.0 1.0 4 Q07021 1
Beta tubulin binding 0.286656517231053 0.2447844623611645 0.8066233252279729 1.0 1.0 19 Q66K74,O75347,Q9UBK9 3
Mirna binding 0.2937494624795912 0.2411108092996524 0.8094692352766868 1.0 1.0 15 Q5TAX3,P98175 2
Protein serine threonine kinase inhibitor activity 0.342529135663421 0.2394389755804784 0.8107652106363099 1.0 1.0 8 P13861,Q8N122,P04792,O75367,O94992 5
Actin filament binding 0.2439535300163098 0.2389693183767243 0.8111293739392955 1.0 1.0 82 Q13045,Q01082,Q9UBK9,Q9UBT7,P35579,O15020,P15311,Q86VI3,Q13576,Q66K74,Q9UPN3,P28289,Q7Z406,P35580,P46940 15
Protein disulfide reductase nad p activity 0.3769898887444965 0.2379684873024161 0.8119055356645648 1.0 1.0 6 Q16881 1
Trna methyltransferase activity 0.323772586811525 0.2367193737850001 0.8128745039749745 1.0 1.0 10 Q08J23,Q13395 2
Nucleocytoplasmic carrier activity 0.2763535753236866 0.2362347961668547 0.813250480065872 1.0 1.0 22 Q9UI26,Q9Y5L0,Q53FT3 3
Tumor necrosis factor receptor superfamily binding 0.3740448926310367 0.2293872881664388 0.8185679153593168 1.0 1.0 6 Q13546,Q14790 2
U3 snorna binding 0.3202061171166974 0.2242780160238954 0.8225409811884112 1.0 1.0 10 Q2NL82 1
Protein self association 0.3063802902131605 0.2240372537961903 0.8227283155709326 1.0 1.0 12 Q15149,P53634 2
Dynein complex binding 0.3458324836256212 0.2141764852152379 0.8304094326934699 1.0 1.0 7 Q8TD16 1
Regulatory rna binding 0.2814625850340184 0.2139322805739695 0.8305998666735184 1.0 1.0 18 P43243,P98175,Q9UPY3,P67809,Q15717,Q9NR30,P22626,Q8TCS8,Q9UGR2,Q9NY93,Q5TAX3,P09651,Q14671,Q8IWR0,Q08211,Q06787,P51608 17
G quadruplex rna binding 0.5719525959367842 0.2091365690504436 0.8343416278802609 1.0 1.0 2 Q06787 1
Ribosomal small subunit binding 0.3086429435403472 0.208000891590927 0.8352282711903922 1.0 1.0 11 P23588 1
Acetylcholine receptor binding 0.571106094808114 0.2074169710211839 0.8356842298271581 1.0 1.0 2 O15258 1
Polyubiquitin modification dependent protein binding 0.282514939950652 0.1983259672887329 0.8427900362275154 1.0 1.0 15 P42566,P46379,Q13501 3
Hydrolase activity hydrolyzing n glycosyl compounds 0.3273296431129734 0.1902202782409679 0.8491365214836564 1.0 1.0 8 P23396,O43598 2
Integrin binding 0.2699756062053765 0.1864642516307321 0.8520807102624797 1.0 1.0 20 Q9Y2I1,Q08431,P12814,P35579,P46939,P06756,P20073,P09429,Q03001 9
Lysine acetylated histone binding 0.2940553977543622 0.1826426471529352 0.8550784195510208 1.0 1.0 12 O60885,O95619,O43149,Q8WWQ0 4
Double stranded methylated dna binding 0.5581264108352009 0.1821422746285534 0.8554710732310831 1.0 1.0 2 O75367 1
O acetyltransferase activity 0.5555869074491971 0.1774383869522521 0.8591640572396801 1.0 1.0 2 O15228 1
Double stranded rna binding 0.2444294883969782 0.1748037166978598 0.8612338678037856 1.0 1.0 41 P08670,P08238,P12814,Q15056,P23588,Q96KR1,Q9NX74,P26038,Q86UE4,Q9H6R0,Q9NUL3,O95793 12
7s rna binding 0.3317321277196915 0.1719369166848772 0.8634871234212933 1.0 1.0 7 P09132,O76094,Q9UHB9,P49458,Q13868,P37108 6
Molecular function activator activity 0.2743118148281369 0.1694702411398945 0.8654267779052276 1.0 1.0 15 P25685,Q96DA6,Q96KC8,Q8IXB1,P05026,Q99543,Q8NFQ8 7
Cadherin binding involved in cell cell adhesion 0.2961929770868381 0.1679487676180578 0.8666235839664462 1.0 1.0 11 O96013,Q9NYL9,O00151,Q9UQB8,P31949 5
Nuclear receptor coactivator activity 0.2546018428860347 0.1643055125617717 0.8694906422749582 1.0 1.0 26 O75528,Q96PK6,Q9Y2W1,Q9UHV7,Q9NVC6,P17096 6
Nucleobase containing compound transmembrane transporter activity 0.2699509432601434 0.1642288206717678 0.8695510135107141 1.0 1.0 17 Q8IWT6,P41440 2
Telomeric dna binding 0.2633521850297803 0.1615131860489298 0.8716892267370966 1.0 1.0 20 Q14103,P19338,Q92900,P22626,Q96Q15 5
Alpha catenin binding 0.3917248745216047 0.1601263401358481 0.8727815524586762 1.0 1.0 4 P19022 1
Lipase activator activity 0.5244143381315076 0.1587771444534469 0.8738444564412651 1.0 1.0 3 Q12846,P42574 2
Lipase inhibitor activity 0.3557456775499495 0.1569722141203229 0.8752667465174244 1.0 1.0 5 P12429 1
Oxidoreductase activity acting on a heme group of donors 0.3255025763534541 0.154520954739267 0.877198990145555 1.0 1.0 7 Q7KZN9,P00403 2
Sh2 domain binding 0.2796324743650184 0.1528549788174496 0.8785126402867676 1.0 1.0 13 Q8NEM2,Q07666,Q13017,P46108,Q13501 5
Protein c terminus binding 0.2430437463172704 0.1501394597156715 0.8806545884600452 1.0 1.0 60 P11940,Q6KC79,Q03001,O95619,P19338,P15311,Q9Y5K6,Q9UI14,P49454,P07196,Q12834,P19447 12
Cargo adaptor activity 0.2989754910570534 0.137476226522157 0.8906543827998494 1.0 1.0 9 Q9BXS5,Q96CW1,P53680 3
Mhc protein binding 0.2970969173382835 0.1322785113818421 0.8947640034407367 1.0 1.0 9 Q9NUQ9 1
Isopeptidase activity 0.282838158742334 0.1293445625690805 0.8970850117308233 1.0 1.0 11 Q92905,O15372,Q9P0U3 3
Protein folding chaperone 0.2458868226821879 0.1269996642045559 0.898940664323721 1.0 1.0 25 P07900,P25685,Q9H2J4,P04792,P48723,P54652,Q96A33 7
C4 dicarboxylate transmembrane transporter activity 0.3327683615819378 0.1244890802097608 0.9009280458545516 1.0 1.0 6 Q9H936,Q9UJS0,Q9UBX3,Q15758,O75746 5
Calcium dependent protein binding 0.2501399703001806 0.1234610809833331 0.9017419913356384 1.0 1.0 21 P04083,Q99584,Q9H9H4,Q99816,P50995,P20073,P31949,O94979,Q9NW64,P12429 10
Sphingosine n acyltransferase activity 0.5011040427309522 0.1226786937473924 0.9023615363298132 1.0 1.0 3 Q8N5B7 1
Peptide binding 0.2284865125670087 0.1226285356002797 0.902401256838613 1.0 1.0 82 Q7Z569,Q15392,Q8WTV0,Q9BYT8,P24390,Q9BVL2 6
Histone h3 methyl lysine 9 demethylase activity 0.4967541631385651 0.1166046531920011 0.9071733501690152 1.0 1.0 3 O60341,Q7LBC6 2
Peptidase activity 0.2891398535179389 0.1133456624563804 0.9097565170626468 1.0 1.0 131 P81605,Q9NZ08,P28070,P61009,P49721,P50579,Q9NUQ7,Q9BYT8,P20618,Q4J6C6,Q9HD42,P28072,Q9P0U3 13
Metalloendopeptidase activity 0.2562123507965558 0.1133135818332083 0.9097819498467388 1.0 1.0 15 Q9BYT8 1
Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides 0.3339741362821429 0.1129121252434538 0.9101002232554756 1.0 1.0 5 Q05682 1
Zinc ion binding 0.3227415615247825 0.1118617525824732 0.9109330232288672 1.0 1.0 160 Q9Y5J9,Q8IYH5,Q9NXS2,Q99584,O95159,O95486,P19474,Q9UNY4,O43149,Q5JRX3,Q8N4Q0,Q5F1R6,Q9HD42,P09884,Q13501,Q99707,P09874,Q8NB78,Q96KR1,P49588,Q92900,Q9Y6X9,Q14527,P38398,Q14839,Q6NZY4,Q15637,Q96T88,Q9BTC8,O43823,Q7Z569,Q9UPT9,Q9NZ08,Q969S3,Q9GZZ9,P41229,Q9UPN9,Q07864,Q9NRW3,Q5TAX3,P32321,O75928,Q05682,Q9Y5L4,P53992,Q15075,Q5VUA4,P34897,P46939,Q86WB0,Q7Z6E9,Q9NUD5,O95071,Q9BQG2,Q6P179,Q13263,Q96KQ7,Q92974 58
Protein arginine n methyltransferase activity 0.3258528639405281 0.1098706656340625 0.9125119471001946 1.0 1.0 6 Q6P2P2 1
Adenyl nucleotide exchange factor activity 0.2980649493811934 0.1091780283883462 0.9130612869276172 1.0 1.0 8 O95429 1
Atpase regulator activity 0.2980649493811934 0.1091780283883462 0.9130612869276172 1.0 1.0 8 O95429 1
Transcription coactivator activity 0.2434142759429757 0.1089722360234419 0.9132245116108676 1.0 1.0 95 Q05086,Q96PK6,P19474,O43149,Q86TU7,O60885,Q9NVC6,P17096,Q13573,Q9Y6J9,P38398,Q13503,Q9Y2W1,Q9BTC8,P35637,Q9UPT9,Q86UE4,Q9UHV7,P09429,Q969G3,O75528,O00151,Q5VTR2,Q969T9,Q13263,Q92905 26
Dopamine receptor binding 0.3284662592055859 0.1030275991009917 0.9179410665895612 1.0 1.0 5 P50570 1
Estrogen receptor binding 0.2569287186304664 0.1022897384981063 0.9185267000768268 1.0 1.0 14 Q8TDD1,Q969T9,O43815 3
Phosphatidylinositol 3 kinase binding 0.4845557077613379 0.1006675083896842 0.919814404860319 1.0 1.0 3 P50570 1
Amp binding 0.3032713427232741 0.098903112914796 0.9212151972783764 1.0 1.0 7 P17858 1
Translation regulator activity 0.221478490576807 0.0947215033391186 0.9245360375755888 1.0 1.0 80 Q14011,Q15056,Q04637,P05198,P55884,O15372,P43897,P11940,P56537,P23588,P06730,O75822,Q14152,Q9Y6M1,P00374,O60573,P34897,P51114,P55010,Q92905,P41214,O00178 22
Mrna binding 0.3307594041321108 0.0942056732239955 0.9249457782379036 1.0 1.0 170 P38159,Q92804,P52298,Q14011,Q9BX40,Q96PK6,Q96MU7,P19338,Q9Y2R9,O60508,Q04637,O75153,Q9BYD1,Q14103,P05198,P46777,Q99729,Q08170,P14618,Q15637,Q9H6R0,Q96T37,Q96PU8,P07910,Q96AE4,P52272,P56537,P35637,Q01085,Q07666,P11940,O60306,Q9UQ35,P12270,O00267,P22626,Q07021,Q7Z739,Q9UN86,Q9Y6M1,Q14152,P35580,P00374,P52756,P34897,O43390,P51114,O75150,Q8IY67,O60506,P46782,P23396,Q13310,Q5VTR2,P52758,Q9UKA9 56
Thyroid hormone receptor binding 0.2536199594624544 0.0938978051301034 0.9251903373882288 1.0 1.0 14 Q9NVC6,Q9UHV7 2
Large ribosomal subunit rrna binding 0.3518498364368456 0.0909858881065352 0.9275038042024166 1.0 1.0 4 P62829 1
Heat shock protein binding 0.2325259143588885 0.0906147935907967 0.9277986767085372 1.0 1.0 54 Q9NZJ4,P08238,P25685,P51617,Q9H3U1,Q8IXB1,P46379,Q96EY1,Q02790,P23396,P49815,O95433,P48723,P12270,P54652,Q53FT3,Q99543,Q9NUL3 18
Histone h3 di monomethyl lysine 9 demethylase activity 0.4966139954853145 0.0902916194811132 0.9280554796353544 1.0 1.0 2 Q7LBC6 1
Tubulin binding 0.2778869715893681 0.0900953595694184 0.9282114367516356 1.0 1.0 125 Q9BSJ2,P50570,P78559,Q9UBK9,Q9P265,P49454,Q13586,Q9Y3E1,Q96ED9,Q9UGJ1,Q96Q89,Q9C0F1,Q14203,Q66K74,O75347,Q03001,P50402,P52732,P41208,Q2M1P5,Q9UPN3,Q15814,O00429,Q86VS8,Q8NBT2,O75122,Q6NUK4,P23396,P15311,Q9NQT8 30
Metal dependent deubiquitinase activity 0.2990949077721049 0.0896213919433174 0.9285880844992564 1.0 1.0 7 Q92905,O15372 2
3 5 exonuclease activity 0.2339768309725007 0.0855918564214573 0.9317908723372156 1.0 1.0 24 Q07864,Q9BQ61,Q9HBH5,Q9H0D6 4
Protein adp ribosylase activity 0.4710230350636171 0.0848440529224384 0.9323853706130552 1.0 1.0 3 Q9UGN5 1
Pre mrna 3 splice site binding 0.4892776523701839 0.0823105615283458 0.9343997560357332 1.0 1.0 2 Q01081 1
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.4665800109885731 0.080064619688884 0.9361858617780854 1.0 1.0 3 Q16850 1
Translation activator activity 0.3403793181836446 0.0754165600021143 0.9398832837550304 1.0 1.0 4 P11940,Q6PKG0 2
Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor 0.2825862468344698 0.0740849395535994 0.940942798822088 1.0 1.0 8 Q16881 1
Wd40 repeat domain binding 0.3379955847251705 0.0724160583034172 0.9422708056678748 1.0 1.0 4 Q96K76 1
Phospholipase c activity 0.3376623376623469 0.0720029411266337 0.9425995672481692 1.0 1.0 4 Q01970,P19174,P16885 3
Chromatin binding 0.3379318112303324 0.0692348332607935 0.9448026966872862 1.0 1.0 181 P38159,Q9Y619,Q9UBK9,Q9H2P0,Q9Y5B9,Q9UQ84,O75419,Q15424,Q9HCD5,Q7Z4L5,O75717,O60885,P49454,Q9BQ67,P09884,Q01105,P17096,Q9H0U9,Q99549,O60264,Q15233,O14802,Q14103,P17480,Q8NB78,Q6KC79,Q92900,Q9Y6X9,Q9HCK8,Q14839,P82979,P07910,Q9BTC8,P19447,P35637,Q9Y483,Q07864,O95347,Q9UGN5,P12270,O00267,O00213,P23246,Q9UKL0,O60216,Q04837,P34897,Q969G3,Q9NTJ3,P28370,O96028,Q5VTR2,Q15022,P37198,Q96L91,Q99543,Q969T9,Q13263,Q96KQ7 59
Epidermal growth factor receptor binding 0.2884995761514617 0.0677510377976095 0.9459838203266592 1.0 1.0 7 Q92600,P18085,O00291,O95219,O60749,P62993 6
Centromeric dna binding 0.4518769404459289 0.065663789087477 0.9476455022882156 1.0 1.0 3 Q99661,P43246 2
Catalytic activity acting on a rrna 0.2686772059477726 0.0641154656519048 0.9488782873739474 1.0 1.0 9 Q86W50,Q9UNQ2 2
Single stranded telomeric dna binding 0.2980225988700645 0.0598882325135879 0.952244652166674 1.0 1.0 6 Q92878,P15927,P27694,P22626,P09651 5
G rich strand telomeric dna binding 0.2979384354701975 0.0573709156204536 0.9542497308030014 1.0 1.0 5 P09651,P15927,P27694,P22626 4
Potassium ion transmembrane transporter activity 0.3233483959341222 0.0556997406836549 0.95558100608799 1.0 1.0 4 P05026 1
Mhc class i protein binding 0.2716223855285491 0.0525459914956391 0.9580936500130162 1.0 1.0 8 P68371,P51572,Q03518,P06576,Q9BUN8,P07437,P55072 7
Aspartic type endopeptidase inhibitor activity 0.4537246049661281 0.0516252588846218 0.9588272924929762 1.0 1.0 2 Q13464 1
Clathrin light chain binding 0.4486455981941184 0.0482331703436834 0.9615304148309636 1.0 1.0 2 O00291 1
Nadplus adp ribosyltransferase activity 0.2847430179720319 0.042234484871232 0.966311772124414 1.0 1.0 5 Q9UGN5 1
Polynucleotide adenylyltransferase activity 0.4294582392776386 0.0373679867342126 0.970191597719934 1.0 1.0 2 P51003 1
Promoter specific chromatin binding 0.2138847344529036 0.0360974741023298 0.9712046363912964 1.0 1.0 24 Q6KC79 1
Insulin receptor binding 0.261358922889301 0.0348445730801371 0.9722036780162356 1.0 1.0 8 O60749,Q8WWQ0 2
G quadruplex dna binding 0.2983746493673697 0.033596150237256 0.9731991922025762 1.0 1.0 4 P36776 1
Transferase activity transferring one carbon groups 0.2099266239703986 0.0302601596273549 0.97585957002258 1.0 1.0 70 Q05682,Q9UNQ2,Q96RS0,P34897,Q99707,O60725,Q13395,O96028,Q86TU7,Q86W50,Q6P2P2,Q9BV86,Q7L2J0,Q5HYK3 14
Double stranded rna adenosine deaminase activity 0.4116817155756155 0.0297439672412876 0.9762712466315996 1.0 1.0 2 Q9NZI8 1
Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines 0.2460739798517362 0.0239441338657557 0.9808971706281022 1.0 1.0 9 P13995,P32321,Q9NRW3,P31939 4
Retinoic acid receptor binding 0.2536704329237289 0.0231046273119299 0.9815668146114844 1.0 1.0 8 P17096,Q13573 2
G protein coupled receptor activity 0.3823882357218843 0.0230820198059166 0.9815848479822364 1.0 1.0 3 Q99720 1
Neurotrophin binding 0.3896726862302409 0.0229756411276862 0.981669703383615 1.0 1.0 2 Q99523 1
Dna helicase activity 0.1965968836744505 0.0185704038938506 0.9851838130349118 1.0 1.0 41 P49736,Q86WJ1,P33991,Q92900,Q9HCK8,Q14839,Q9Y620,P19447 8
Myosin v binding 0.2639751552795099 0.0143490811176799 0.988551482583413 1.0 1.0 4 P61106,P20337,P61006 3
Oxidized dna binding 0.2606089710999469 0.0141161026637564 0.988737353667781 1.0 1.0 6 P43246,P18887,P23396 3
L glutamine transmembrane transporter activity 0.3058690744921024 0.0133284226614675 0.989365772195672 1.0 1.0 2 Q15758 1
Phosphatidylglycerol binding 0.3448509246477618 0.0130652834318287 0.9895757086419972 1.0 1.0 3 Q9UJZ1 1
Nedd8 specific protease activity 0.3427371180914959 0.0126834526302772 0.989880340294248 1.0 1.0 3 Q92905 1
Molecular adaptor activity 0.2618630941530158 0.0124046733540915 0.9901027564741958 1.0 1.0 125 O14653,P78559,Q9BXS5,P35579,Q9UH99,Q9Y2Q5,P46108,Q7KZN9,Q04637,O43752,P07196,Q9UDY2,Q93034,Q9Y3I1,P55884,Q02790,Q6SZW1,O60271,P46940,O95721,Q07666,Q86Y82,Q8TD16,Q9UNK0,P05026,Q9NX63,P12270,Q9UN86,Q13428,Q92542,Q13617,Q99996,Q9UHI6,Q96CW1 34
Cyclohydrolase activity 0.324003575206178 0.0099452920621058 0.9920649358191772 1.0 1.0 3 P13995 1
Kinase inhibitor activity 0.201908974116628 0.0085562639230213 0.9931731724160472 1.0 1.0 20 P13861,Q9NX74,Q86XI2,P04792,O94992,Q9UHD1,O75367,Q13217 8
L serine transmembrane transporter activity 0.3059554050239906 0.0082027502902419 0.9934552255816906 1.0 1.0 3 Q15758,Q9H9B4 2
Type i transforming growth factor beta receptor binding 0.2825289302850685 0.0068559450905011 0.9945297901162192 1.0 1.0 3 P62942,Q9UNH7 2
Transmembrane transporter binding 0.1818343016278453 0.0028315536045835 0.997740750114814 1.0 1.0 31 P08238,P12814,P14314,Q9HD47,Q9HD26,Q99996,Q96CW1 7