diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..777a41c78de2c91cf5017d11559c7632b59b9cc9 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b208806d1b0f0b2a4acdb9220a935c63962df2da407b10f132b5059cb8bc189a +size 87134 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..09db1cb3679d3c71b8aee50fa0531d340a7cc178 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 57, + "title": "Average number of proteins per term", + "value": 3.0 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2682b51f2118413b4717c40469db914a1854fb40 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fe2570c1fde67af11e693749b9214b8f0d40788c --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.8384993938542339 1.2093613217912274 0.2265240613921706 0.9999995620060972 0.3397860920882559 3 Q9HB40 1 +Histidine acid phosphatase active site [IPR033379] 0.6029737165813339 0.3653379103803714 0.7148591828533533 1.0 0.8149394684528227 3 Q9NPH0 1 +Tyrosine-protein kinase, active site [IPR008266] 0.3896726862302464 0.1734054973475071 0.8623327043070854 1.0 0.945249310490459 5 P41240,P07947,Q15375,Q13308 4 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5e6f248a0220ccc8a4080789a6f61fcfd3cea12c --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "NCEH1", "NEK9", "NME1", "NME3", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PPIP5K2", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ACP6", "CSK", "EPHA7", "PTK7", "SCPEP1", "YES1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..829f88c12f40caae313f077d3dbfaccee9ee202d --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:527fecc1544136e3a1d2defefbadbad0f79c1ddc9dd1be76c992fdefb63e5bbe +size 191798 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5090a3de2d5b872606b4d7d51fbf2ba7b5743525 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:638d251725af56e05b49c315844ed29998ff59db4b3da1165b4b6126a8cafc30 +size 141051 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c3df6b8c03cd0a0a8cb04284ee9324ea4a8fcec7 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe7e4306d02f6472ea4de99c3cd7b3948112a93b7c4e4aa3fda77475aae240ad +size 82367 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bc64ba61b00345fdc1244a8dec37153ca813e1c6 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EF-Hand 1, calcium-binding site [IPR018247] 15 40 2.708759035031681 0.0067535369699753 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 1.988230874796369e-05 0.3121781622201707 0.0009512079801521 0.000626517772181 2.3299992346197743e-05 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ce2b16be0b186c29405ec5f34206d6a339a207e5 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 5.258064516129032 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d2fe1b9522b4a5a433bf0f71864651b6b9b0180d --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2646809ce0154f7d3e99d453bfc312e523eb0a96 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.5031837158386864 2.708759035031681 0.0067535369699753 0.1894723343344707 0.0448925295078333 40 Q96D71,Q6NUK1,O75746,P80303,Q9BRK5,P41208,Q9Y680,Q14257,O43852,Q02818,O95202,Q96AY3,Q9NWM8,Q9BPX6,O95302 15 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d500614bb2dcb8e632bda0d1017f81dba89632b1 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "AURKA", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "CHEK1", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "LETM1", "LRP2", "MACF1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "LETM1", "MICU1", "NUCB1", "NUCB2", "RCN2", "REPS1", "SDF4", "SLC25A12", "SLC25A24"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c0659230848f71daf39611a1b9a028809791cf86 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "ABC transporter-like, conserved site [IPR017871]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2d8d745692e396fbb61193fb5035e9955d53426e --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cda9de0e43c4aa508781715ee00361b72133fa8a9f11070cc259050e325d379 +size 183774 diff --git a/interpro_conserved_site/advanced/plot_1.png b/interpro_conserved_site/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c5f11d289dbb4cf0583874ed97bb8410c998e488 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c9174022ba64188dc4cef20696d39bcb9c9d9783638c7962d5644c3322cf749 +size 186417 diff --git a/interpro_conserved_site/advanced/plot_2.png b/interpro_conserved_site/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..1d32d31cb0908fbbbbe2d91d49f03b9df6bb477e --- /dev/null +++ b/interpro_conserved_site/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74fef37740dc70527e3e151f94ae2f93bb409041b97eb8acece072344e67640e +size 192853 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f9310b63145bf16e9cb8cb517fd4fc210797134b --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "ABC transporter-like, conserved site [IPR017871]", "3": "DnaJ domain, conserved site [IPR018253]", "4": "14-3-3 protein, conserved site [IPR023409]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..adccb1f69ab35d31a98574cf0b381993cce10bb5 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1fdc650e64fef0af85f57737d9c86d99898aa99a0dd01cdc880fa1fe7a75dc68 +size 143707 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c1555fb5b5bd88dda6ddda482d15bf7f7ab75e72 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9fe857cf0c4dd775ec5223dec4fbf27851249daf4d70321e9e73f5d5e0658a3 +size 146059 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..886ae87130ae22fef7f5972d7241ad194310e175 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00d8430e5a995b3f640416b6ae9e97b663d36065f3d804de16a8f85c57cb9c14 +size 143631 diff --git a/interpro_conserved_site/basic/plot_3.png b/interpro_conserved_site/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..73517bcbec2e1ef8ee24bd98194b368e2388cfa6 --- /dev/null +++ b/interpro_conserved_site/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62d39cc4eac75671503801929ec9a9417551bc129bc2ef2f7538078335ab7379 +size 150296 diff --git a/interpro_conserved_site/basic/plot_4.png b/interpro_conserved_site/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..c4ecd257c003da65178fc6e528f8ed4be8b2fb44 --- /dev/null +++ b/interpro_conserved_site/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3fa1aa03638e37c9c1dfb310c6a91d3f19f1f7a3e891b04fcb15349df29116c +size 142334 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0f9dc92f91f356c28b4b905c89bc43bd31580d8d --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3da5d1ed646488eb933c9b12f24eba655272df3e4ae56a9810594d3210a4860f +size 108954 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fd024dc9648fd3a8515c65a041f611e0ae5e6fa0 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Syntaxin/epimorphin, conserved site [IPR006012] 6 7 2.573979789974844 0.0100536145608001 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 0.0026425445039808 1.0 0.1180585699575878 0.003355333516566 0.0027834726260547 +Intermediate filament protein, conserved site [IPR018039] 6 8 2.555819086681196 0.0105938181701352 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0093478027703867 1.0 1.0 0.0693365470158766 0.0098193480789534 +ABC transporter-like, conserved site [IPR017871] 9 16 2.359372818459103 0.0183058544910226 2.7694174757281553 10.218446601941748 0.3896442308636141 0.4819689640161482 2.0043003889175366 2.2319066503087304 0.948959154182388 0.2971074262916467 0.0859119874297797 1.0 1.0 0.0983610682747182 0.0888008652079453 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..31d9f215f0f2b61be72959b81e1d7eb80cb92ef1 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 289, + "title": "Average number of proteins per term", + "value": 2.7993079584775087 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..672d71ca505bbda27b8b61cb0573808b39e065b5 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6a4e1dabd0a646cc2e3da96e030a11c7ca06f3a8 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,30 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Syntaxin/epimorphin, conserved site [IPR006012] 0.8286278938452676 2.5739797899748433 0.0100536145608001 0.9460770231221468 0.0926909743196627 7 O43752,O60499,Q9P2W9,O15400,Q86Y82,Q13190 6 +Intermediate filament protein, conserved site [IPR018039] 0.7804381929293371 2.5558190866811956 0.0105938181701352 0.953946245607325 0.0926909743196627 8 P07196,Q03252,Q16352,P07197,P20700,P08670 6 +ABC transporter-like, conserved site [IPR017871] 0.6025378164796328 2.359372818459103 0.0183058544910226 0.9952013166407336 0.1125615308065008 16 P33897,Q99758,O75027,Q03518,O14678,P08183,Q9NP58,P33527,O15439 9 +Haem oxygenase conserved site [IPR018207] 0.9935156470256552 1.8774856190009963 0.0604515665384903 0.999999985084393 0.2060872373106376 2 P09601 1 +Tetraspanin, conserved site [IPR018503] 0.9788494077834176 1.7574881333214545 0.078834642762549 0.9999999999506184 0.2449807715954481 3 Q9H1Z9,O43657 2 +Thioredoxin, conserved site [IPR017937] 0.6111390278723082 1.737529194237108 0.0822938055402942 0.999999999983352 0.2504594925708507 10 Q9H1E5,P07237,Q9H3N1,Q96JJ7 4 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.8892021426557666 1.4439608310736685 0.1487499935869372 1.0 0.3520049291271034 2 P11279 1 +Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.3949992283021674 2 P05067 1 +Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.3949992283021674 2 P05067 1 +Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.3949992283021674 2 P05067 1 +Glycoside hydrolase, family 35, conserved site [IPR019801] 0.8446574570059082 1.2583041951851133 0.2082817645546937 1.0 0.4180099302521284 2 P16278 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.824591088550473 1.1551173010750473 0.2480423942330052 1.0 0.4595144354701186 3 P04439,P55899 2 +Clathrin adaptor complex, small chain [IPR000804] 0.6231273892747867 0.9192961366646288 0.3579406980106432 1.0 0.5715185730667176 4 P61923 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.7504933746828105 0.8737712783333675 0.3822428248023439 1.0 0.5939149267090184 2 Q9BTY2 1 +Ubiquitin interacting motif [IPR003903] 0.5569186440986885 0.8124184669906437 0.4165515532852926 1.0 0.6136772807542781 5 Q92783,Q8IZ07,O14964 3 +Proteasome beta-type subunit, conserved site [IPR016050] 0.4475059122335207 0.7582256344683315 0.4483159175610014 1.0 0.635114216544752 8 P28072 1 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.6962655751612685 0.6711124900743058 0.5021488707670168 1.0 0.694358964840516 3 Q9BXS5 1 +EGF-like calcium-binding, conserved site [IPR018097] 0.5611245371303992 0.6623273826173357 0.5077614315207377 1.0 0.6987764462356819 4 P98164 1 +Guanylate kinase, conserved site [IPR020590] 0.4753207561976715 0.6007904355791382 0.5479795752882182 1.0 0.7297976832179496 6 Q14168,Q8N3R9,Q5T2T1 3 +Heat shock protein Hsp90, conserved site [IPR019805] 0.6720248166948631 0.5861559809715717 0.557770699625139 1.0 0.735786994052171 3 P14625,P07900 2 +Dynamin, GTPase region, conserved site [IPR019762] 0.6699097506311338 0.5788964777619654 0.5626590269800147 1.0 0.735786994052171 3 O00429 1 +DnaJ domain, conserved site [IPR018253] 0.387383019013346 0.5392827468372139 0.5896917717974426 1.0 0.7441961661548511 11 O60884,Q96KC8,Q9UBS4,Q96EY1,Q9NVH1 5 +Ras GTPase-activating protein, conserved site [IPR023152] 0.6384658770445556 0.474353503243369 0.6352478441113565 1.0 0.7779094362211103 3 Q86VI3,Q13576 2 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.6113519633954624 0.3900989726082025 0.6964633625141556 1.0 0.8148903310388299 3 P98164 1 +14-3-3 protein, conserved site [IPR023409] 0.416596104995761 0.3504330631815777 0.7260137167315803 1.0 0.82900573478588 6 P63104,P61981,Q04917,P31946,P62258 5 +Oxysterol-binding protein, conserved site [IPR018494] 0.4157185741287966 0.3469789720779783 0.728607116386206 1.0 0.82900573478588 6 Q9H1P3,Q9BXB4,Q9BZF1,Q96SU4 4 +Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.3249031711118448 0.2218928788175288 0.8243972742384691 1.0 0.9128383611299524 11 Q6YN16,Q06136,Q53GQ0 3 +Vinculin, conserved site [IPR000633] 0.5511700028192931 0.2153782453569471 0.8294724296995133 1.0 0.914952412912822 2 P18206 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.491257755217158 0.1076432392086626 0.9142786963136892 1.0 0.9678627957313414 3 P26583,P09429 2 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bd56f256b8f1846d4b1379ed87c18c0ee2595812 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATAD2B", "ATM", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CDX2", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160B2", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGAV", "IVD", "KDM2A", "KDM5C", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NMT2", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN3", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ANKRD13A", "AP1M1", "APP", "COPZ1", "DNAJA2", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC11", "DNM1L", "FCGRT", "FUCA2", "GLB1", "HGS", "HLA-A", "HMGB1", "HMGB2", "HMOX1", "HSD17B12", "HSDL2", "HSP90AA1", "HSP90B1", "INA", "IQGAP2", "IQGAP3", "KDSR", "LAMP1", "LMNB1", "LMNB2", "LRP2", "MPP2", "MPP5", "MPP7", "NEFL", "NEFM", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PSMB6", "STAM", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "TAP1", "TMX1", "TMX3", "TMX4", "TSPAN10", "TSPAN6", "VCL", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d7c934fb92727b3e92ee23660ae8a1bf849bd1d1 --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "EF-hand domain [IPR002048]", "2": "ABC transporter type 1, transmembrane domain [IPR011527]", "3": "Immunoglobulin-like domain [IPR007110]", "4": "Intermediate filament, rod domain [IPR039008]", "5": "ABC transporter-like, ATP-binding domain [IPR003439]", "6": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "7": "Dynamin, N-terminal [IPR045063]", "8": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "9": "Phospholipid/glycerol acyltransferase [IPR002123]"} \ No newline at end of file diff --git a/interpro_domain/advanced/plot_0.png b/interpro_domain/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1dd36fdbe273ab3cefef994ce99e7a61a8e081e6 --- /dev/null +++ b/interpro_domain/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f909d0470c5f0badb7c7d13fd748ecba88b77a53e98f581ed73df864cc7d978d +size 191247 diff --git a/interpro_domain/advanced/plot_1.png b/interpro_domain/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..38054fa974e327914d5610a205a4f1dc1cd73746 --- /dev/null +++ b/interpro_domain/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8b7dd003890d3800f18939ba7cb0a19db2933f1ab7c927d9ecbdab60973a21b9 +size 202649 diff --git a/interpro_domain/advanced/plot_2.png b/interpro_domain/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..732c3bdf34d269b9eba92b1a1a02447f497e5481 --- /dev/null +++ b/interpro_domain/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f26fecc68189738a31ba62ab6022f4c7615ca76c283f2740a169a1232ed33b67 +size 189507 diff --git a/interpro_domain/advanced/plot_3.png b/interpro_domain/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..beaac92368b07ef1d7f68675e189b45b007482c2 --- /dev/null +++ b/interpro_domain/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:575e88ae3c47df3782669ae47a668843a3f31320a50f53f92ca75e4d1578d6c0 +size 190437 diff --git a/interpro_domain/advanced/plot_4.png b/interpro_domain/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..23306f37cc19bfdaba6280efe56d130b4e351599 --- /dev/null +++ b/interpro_domain/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d585a531c4a53d416ac4a4dbfae0e77cdbd07ac50a57c2959e39b0a373d987e +size 181844 diff --git a/interpro_domain/advanced/plot_5.png b/interpro_domain/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..cce4451d48f95d10b6659b69e1f196d1e2491a46 --- /dev/null +++ b/interpro_domain/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c523703023e78f4f19810d1f504b2ebec344491ccc017809b325db67e97c8909 +size 191196 diff --git a/interpro_domain/advanced/plot_6.png b/interpro_domain/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..0e1398b109281936a3435b07e8e70b5c76a56176 --- /dev/null +++ b/interpro_domain/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a6c599e302b52995e23ea87d0e27c908593d0b1b9e207d1aeabf4d5070e62ee +size 189356 diff --git a/interpro_domain/advanced/plot_7.png b/interpro_domain/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..436bda42b2ea4c887277adacf5f4927080ff77f8 --- /dev/null +++ b/interpro_domain/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a691ff4be81b1bddc5558a021ef9a0130eadff450cde4cce6bc404993c8e185 +size 181832 diff --git a/interpro_domain/advanced/plot_8.png b/interpro_domain/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..33306c5c500349528f329dc57521f351695ec319 --- /dev/null +++ b/interpro_domain/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f67b24570132b264b5d0dccdbc5d9076bb00cc5315feeb5aa43bb73640949467 +size 188690 diff --git a/interpro_domain/advanced/plot_9.png b/interpro_domain/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c79a2b73a409b64fc76f42441f5b6870ec317e14 --- /dev/null +++ b/interpro_domain/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cd3feb9a3146ab0afd5f24411a89eac065d5ba850c2d6903b42cb877f3897124 +size 190803 diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8395313f0a65e0766fc43add33c6adb9c4cb6a29 --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "EF-hand domain [IPR002048]", "2": "ABC transporter type 1, transmembrane domain [IPR011527]", "3": "Immunoglobulin-like domain [IPR007110]", "4": "Intermediate filament, rod domain [IPR039008]", "5": "ABC transporter-like, ATP-binding domain [IPR003439]", "6": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "7": "Dynamin, N-terminal [IPR045063]", "8": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "9": "Phospholipid/glycerol acyltransferase [IPR002123]", "10": "Target SNARE coiled-coil homology domain [IPR000727]", "11": "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "12": "Band 7 domain [IPR001107]", "13": "Importin-beta, N-terminal domain [IPR001494]", "14": "CBS domain [IPR000644]", "15": "Guanylate kinase-like domain [IPR008144]", "16": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "17": "Thioredoxin domain [IPR013766]", "18": "RecF/RecN/SMC, N-terminal [IPR003395]", "19": "Proteasome component (PCI) domain [IPR000717]", "20": "14-3-3 domain [IPR023410]", "21": "Histidine kinase/HSP90-like ATPase [IPR003594]", "22": "DnaJ domain [IPR001623]", "23": "K Homology domain, type 1 [IPR004088]", "24": "FERM, N-terminal [IPR018979]", "25": "FERM, C-terminal PH-like domain [IPR018980]", "26": "PDZ domain [IPR001478]", "27": "K Homology domain [IPR004087]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b77d51c985ca5795305cd435b226741b65acc84a --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba675c20e4270db14cdf57a93efa2fee7dc7aa3be7a8c3be81611ec3419b9761 +size 144502 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f1244b47a4ce496f238aa02254b422c1e1a1a38b --- /dev/null +++ b/interpro_domain/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24042951a77a8ceb9bd470e175aeee6ed4e1662ebca5e924d66a5729ae892f38 +size 136276 diff --git a/interpro_domain/basic/plot_10.png b/interpro_domain/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..b2b018fd91144f5eca1dc6c2242dcc762bfd4849 --- /dev/null +++ b/interpro_domain/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aacfabd0d7958ecf2c1737b7d511f6c65f5a8e53ce8cbf5a1d1c949058848f2a +size 141533 diff --git a/interpro_domain/basic/plot_11.png b/interpro_domain/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..4954b5649ca1c5568ea3ba2a5a37c36b048f6c1a --- /dev/null +++ b/interpro_domain/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e9ece2ce9dcb52963de8bdcae4121fdb0cc8aae21e278631ba37da4436b0ae6 +size 143894 diff --git a/interpro_domain/basic/plot_12.png b/interpro_domain/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..24e849c2a14e39f78f87c70b6d6b4fadf9ddd434 --- /dev/null +++ b/interpro_domain/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a2be55843d677f4725408244a5b7a26eb340acdfcfbdd1fcfa4ad5ab9ee2f93 +size 127185 diff --git a/interpro_domain/basic/plot_13.png b/interpro_domain/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..bd1a36f7cb09b6204f0c9ad0d05bdc28412f443d --- /dev/null +++ b/interpro_domain/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb801f4e246958e05665915bfa9e03d4bc40b0a26c5adb2ee9ead0f60717a98f +size 143388 diff --git a/interpro_domain/basic/plot_14.png b/interpro_domain/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..d43d96d658cf5cd0af8b6027a389820ad8ac7451 --- /dev/null +++ b/interpro_domain/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ed6164ad5e724babadaedad13e886e4204c082497bdc79aa468b25b852f6393 +size 129134 diff --git a/interpro_domain/basic/plot_15.png b/interpro_domain/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..ef5359c1370f01fdb7b67d144c74f221e3f42ace --- /dev/null +++ b/interpro_domain/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7cc206632473de00b671b2d7cb5229ea338220d564e65a5e526857a7b3533cf4 +size 139696 diff --git a/interpro_domain/basic/plot_16.png b/interpro_domain/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..e4f609e71be548634cfb607c1a66d665d94060d0 --- /dev/null +++ b/interpro_domain/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe1843e064f5508edbda8dd6fec3bb5df86c8a3d75202492615064f5a768cffa +size 143302 diff --git a/interpro_domain/basic/plot_17.png b/interpro_domain/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..8f99e6a7c7bdde323bfc8635ea75481f3e1e3efe --- /dev/null +++ b/interpro_domain/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c94cfd89b55bd2a6ed2c1d5649bfa6929676e346d6f692feb9e7f36a8984cc00 +size 144943 diff --git a/interpro_domain/basic/plot_18.png b/interpro_domain/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..5f16d8610e0cb2977b21de0fbb95d58fff0c5bc0 --- /dev/null +++ b/interpro_domain/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3cfdaab7ee856a0380546fceac0bc0290484a8f7a7de0a4ef1699cf833125e26 +size 126204 diff --git a/interpro_domain/basic/plot_19.png b/interpro_domain/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..0be4fba26ea3d33c1f410372a29c7002d6dcef52 --- /dev/null +++ b/interpro_domain/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:07efb0bd154e701968ce6dfafdcfc30df6f99ad85c4b3018725a1fff768c29cf +size 157311 diff --git a/interpro_domain/basic/plot_2.png b/interpro_domain/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ae24240e7ec8b4b491765a8a8719b6d08b3744eb --- /dev/null +++ b/interpro_domain/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab97b8615f8ede9873c1d454a69daf754f017a912744d496e435b990fca1fa8b +size 130036 diff --git a/interpro_domain/basic/plot_20.png b/interpro_domain/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..b6588f62b994bdd6ee794c69c1c8d88d0eea78d9 --- /dev/null +++ b/interpro_domain/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7aaeaa9fca5d70f8ef951ef5c52c0232563530350f7731c61924594163cbafb8 +size 134986 diff --git a/interpro_domain/basic/plot_21.png b/interpro_domain/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..c8d529d9dd0e77cc6a4cfc5be30d31a6350c44e8 --- /dev/null +++ b/interpro_domain/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0556565a3c57324698df6a524b768bc4bf8f17e48c906783768ae1ea1201222e +size 151945 diff --git a/interpro_domain/basic/plot_22.png b/interpro_domain/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..afc404e6f0569a0912a540e70f6e048ba213d7a7 --- /dev/null +++ b/interpro_domain/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5efdbb00af05b3cad02cd94e619ea61dd3dc2d48df2c7fd3ec990ae43a530583 +size 147423 diff --git a/interpro_domain/basic/plot_23.png b/interpro_domain/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..217093f49f5fadd3259ed91d6b1034fe827fafcc --- /dev/null +++ b/interpro_domain/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:658141bea5e44fd2a5f7ac4769f5a705c1a399ad664fbff7b0d356580b655bdf +size 152823 diff --git a/interpro_domain/basic/plot_24.png b/interpro_domain/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..8f74ee62cd43f9dd45d307644dea2f7b92027f77 --- /dev/null +++ b/interpro_domain/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:837282fce07a70ea4501154abc7181a74be7c0dd801c8f07cb2988e8991a8e06 +size 133691 diff --git a/interpro_domain/basic/plot_25.png b/interpro_domain/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..aa15a958b28706969f869e34e4460a36ad872845 --- /dev/null +++ b/interpro_domain/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:925c76cd485595b9ca81b0147dca1e488e119f75c1f5cf9a88db8f1e853926ca +size 139278 diff --git a/interpro_domain/basic/plot_26.png b/interpro_domain/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..7538b68ef1e0a49c8c1eb38f6528a1ba0a93b493 --- /dev/null +++ b/interpro_domain/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8495f1e62fc4adface3ebfee6572892d2816c8666663ebb84f43831a41eb3e1c +size 163933 diff --git a/interpro_domain/basic/plot_27.png b/interpro_domain/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..7620d7c147ad98906b0a00b9cd1b7fd34940ff00 --- /dev/null +++ b/interpro_domain/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d319a1c548c9475f783da7140f0d67a60f0d06ee005ff68d16dfc203f0e55e9 +size 144934 diff --git a/interpro_domain/basic/plot_3.png b/interpro_domain/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f0b088bc3330770a7af94241b2235a37bad211ad --- /dev/null +++ b/interpro_domain/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62ce832c6f07b3ef3549116b22b98affe1d862b23ddab140d6ad9cb8b5264485 +size 138991 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..82106c1a7d5bfba20e450d976abbcf70397cb894 --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b912666ac8f3118e319c9aefa9d76bfc2167ae6def0daa08510bd6a114d8fa7f +size 142949 diff --git a/interpro_domain/basic/plot_5.png b/interpro_domain/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..2a7eb7adf664bed09c289dc4ec02936aa9ce40a4 --- /dev/null +++ b/interpro_domain/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:439fd5cd961491872f70858262b9ecbb2b8badb50c5230138373c1b1098c55b1 +size 143813 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..a2a051e4150e1fe75f01414bf333eae04543b8de --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d7b202faf2208af018fc1df1472cc15c9baf3f724257bb63640aebe3a675ddc +size 143572 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..cdc4d8f54bbcdc0c3fa42e8f0b4e045ca82e290b --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6815921b78783d025933f616140d8ff4b6b5618d77987c9aa7337f3acceecf79 +size 130875 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..30c5d4e278a8196d637f6ad08a2add8d45fa4fb3 --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e7206f9e4ec5d63adc80d5f08142cbdffa93e24e75d0b6a10366b278371be85 +size 139746 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..e1f4e9ce4f25f675ffc7b04bb79340acf89e5a9c --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fbd506e701261770299b83b95973e101f51e580858f8438379e244301ed72817 +size 142822 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..54c7457863e2770e79f2e2102cb1d77570f27888 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:619f682f1b1b9cf8d5a06cb225191a10dfa6e606bdb4f17139fddb699d7695c2 +size 300608 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..daabbf49fdddd781e638b031e0187a217df998ec --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,14 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 7 12 2.797255922115953 0.0051538691541024 3.1262135922330097 10.111650485436892 0.9686720267359892 0.3700536707457866 1.7316562118191232 1.203619216216406 0.9607394322697528 0.3108814801432357 7.461844281524028e-07 1.0 5.369271916582234e-06 8.796898694645245e-06 8.216606581665977e-07 +EF-hand domain [IPR002048] 18 48 2.639619508557125 0.0082999153805549 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 4.697710250772576e-06 0.3776146865859943 0.0027125023591425 0.000693686312984 5.679966031036118e-06 +ABC transporter type 1, transmembrane domain [IPR011527] 8 11 2.6355715794228343 0.0083995707862485 2.3689320388349513 6.349514563106796 0.6640264147492347 0.3307390797434538 1.7803691733569 2.1393617497725477 1.1694677427725269 0.279101120079799 0.0324301480805536 1.0 1.0 0.0498779046475234 0.0336357980244025 +Immunoglobulin-like domain [IPR007110] 7 14 2.563421821228955 0.0103646039892386 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.4593652761695944 0.4150254222087767 0.6662735487440652 0.5186743225277523 0.4731336176853572 +Intermediate filament, rod domain [IPR039008] 6 8 2.555819086681196 0.0105938181701352 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0192115706028201 1.0 1.0 0.0983610682747182 0.0201372619620155 +ABC transporter-like, ATP-binding domain [IPR003439] 9 16 2.359372818459103 0.0183058544910226 2.7694174757281553 10.218446601941748 0.3896442308636141 0.4819689640161482 2.0043003889175366 2.2319066503087304 0.948959154182388 0.2971074262916467 0.1053751065738953 1.0 1.0 0.1139407547181512 0.1088149775417643 +Zinc finger, RanBP2-type [IPR001876] 4 9 2.3313809804091536 0.0197332795257649 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0026687375683324 1.0 1.0 1.0 0.0028394369313259 +TRAM/LAG1/CLN8 homology domain [IPR006634] 4 5 2.284200000763631 0.0223597795323668 1.691747572815534 3.3592233009708736 1.3447142040916915 0.1822595206051251 1.014281444620711 0.9789470163478144 1.2723870690026748 0.2262567589818981 5.1265180635653765e-05 1.0 0.0921025797166938 0.001485709034831 5.489393781591606e-05 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 5 8 2.231514973742304 0.0256470367803576 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0192115706028201 1.0 1.0 0.4172977923286156 0.0201372619620155 +Dynamin, N-terminal [IPR045063] 6 8 2.112841540954964 0.0346143328103059 3.0970873786407767 6.975728155339806 0.7379849963606689 0.4199536592827374 1.7349327124234004 0.8151438040285356 0.9001171760244049 0.3234417573977254 0.0948139233898727 1.0 1.0 0.2365379696877526 0.0140894483762481 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 6 8 2.112841540954964 0.0346143328103059 3.0970873786407767 6.975728155339806 0.7379849963606689 0.4199536592827374 1.7349327124234004 0.8151438040285356 0.9001171760244049 0.3234417573977254 0.0948139233898727 1.0 1.0 0.2365379696877526 0.0140894483762481 +Phospholipid/glycerol acyltransferase [IPR002123] 5 8 2.085171506913574 0.0370537352823809 2.4611650485436893 6.109223300970874 0.4541526786138767 0.3733328307275969 1.647577392422315 1.6678607828333205 1.200305691546449 0.3080828121567173 0.1772895401336459 1.0 1.0 0.3247468214281712 0.1812716861639223 +Target SNARE coiled-coil homology domain [IPR000727] 6 10 1.994974264897586 0.0460456867560423 3.5024271844660193 8.266990291262136 0.5942034778060385 0.4012381903331891 1.9023475359698396 2.183694577914796 1.0582363712887182 0.3038263160802639 0.0296850028190536 1.0 1.0 0.1219531221716571 0.031065887399213 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..399b8ad4706fe51a882586ac2a0f68e1ab5f506f --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 2796, + "title": "Average number of proteins per term", + "value": 2.270743919885551 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..592a7d7008544078742b08b4ad9846198e1da091 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b42d704ff834c0e0da120f179505eb315d612929 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,263 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.7449814081763355 2.797255922115953 0.0051538691541024 0.9999994684563036 0.155289029367607 12 Q9Y680,P26885,Q02790,Q96AY3,Q9NWM8,O95302,P62942 7 +EF-hand domain [IPR002048] 0.5034412575715447 2.639619508557125 0.0082999153805549 0.9999999999242366 0.155289029367607 48 Q96D71,Q6NUK1,O75746,Q8IYU8,P80303,Q8NF37,Q9BRK5,P41208,Q9Y680,Q14257,O43852,Q02818,O95202,Q96AY3,Q9NWM8,O75071,Q9BPX6,O95302 18 +ABC transporter type 1, transmembrane domain [IPR011527] 0.7473100797535308 2.6355715794228343 0.0083995707862485 0.9999999999427956 0.155289029367607 11 P33897,Q9NP58,O75027,Q03518,O14678,P08183,P33527,O15439 8 +Immunoglobulin-like domain [IPR007110] 0.6554526804628584 2.563421821228955 0.0103646039892386 0.9999999999997768 0.155289029367607 14 Q08722,P55899,P01889,P10321,P04439,Q92859,P35613 7 +Intermediate filament, rod domain [IPR039008] 0.7804381929293371 2.5558190866811956 0.0105938181701352 0.9999999999998832 0.155289029367607 8 P07196,Q03252,Q16352,P07197,P20700,P08670 6 +ABC transporter-like, ATP-binding domain [IPR003439] 0.6025378164796328 2.359372818459103 0.0183058544910226 1.0 0.165381530853357 16 P33897,Q99758,O75027,Q03518,O14678,P08183,Q9NP58,P33527,O15439 9 +Zinc finger, RanBP2-type [IPR001876] 0.7235286585269693 2.3313809804091536 0.0197332795257649 1.0 0.1682141754696307 9 P52756,Q92804,P98175,P35637 4 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8871331828442376 2.284200000763631 0.0223597795323668 1.0 0.1785172631576373 5 P27544,Q96CP7,Q96G23,Q15629 4 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7167406340345546 2.231514973742304 0.0256470367803576 1.0 0.1884021094760411 8 Q9HD20,P16615,P20020,P23634,P05023 5 +Dynamin, N-terminal [IPR045063] 0.6940030944010296 2.112841540954964 0.0346143328103059 1.0 0.2108533214327131 8 P50570,O00429,Q9H223,O60313,Q8IWA4,Q9H4M9 6 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.6940030944010296 2.112841540954964 0.0346143328103059 1.0 0.2108533214327131 8 P50570,O00429,Q9H223,O60313,Q8IWA4,Q9H4M9 6 +Phospholipid/glycerol acyltransferase [IPR002123] 0.6887430264886693 2.085171506913574 0.0370537352823809 1.0 0.2174003834920244 8 O15228,Q92604,Q9HCL2,Q8NF37,Q9NUQ2 5 +Tim10-like [IPR004217] 0.8775740479548734 2.005204583530777 0.0449411802821715 1.0 0.2380417372308049 4 Q9Y5J9,O60220,Q9Y5J6 3 +Target SNARE coiled-coil homology domain [IPR000727] 0.6573177153643665 1.994974264897586 0.0460456867560423 1.0 0.241535363011474 10 O43752,O60499,O15400,O95721,Q86Y82,Q13190 6 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.6459821832942673 1.8572882539773217 0.0632701546406961 1.0 0.2750832296584558 8 O43169,O15173,O00264,Q8WUJ1,O60427 5 +Band 7 domain [IPR001107] 0.6764539808017911 1.8282032864623696 0.0675190479772724 1.0 0.2838845987134644 7 Q99623,Q9UJZ1,P27105,P35232,O94905,O75955 6 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8276445698166601 1.7964033736008438 0.0724303877151302 1.0 0.2950197119899648 4 P07196,P08670,P07197 3 +Immunoglobulin C1-set [IPR003597] 0.824823695345563 1.7844991457240968 0.0743425934968593 1.0 0.2965219563726373 4 P10321,P04439,P55899 3 +MHC class I-like antigen recognition-like [IPR011161] 0.7714446952595758 1.7823253316483445 0.0746961940915 1.0 0.2967080702216521 5 P01889,P10321,P04439,P55899 4 +Reticulon [IPR003388] 0.9577107414716626 1.7293792623015551 0.0837412390443037 1.0 0.3134411035714501 2 O95197 1 +Peptidase M48 [IPR001915] 0.956019171130532 1.7223580936596783 0.0850046700517821 1.0 0.3139656722851695 2 O75844 1 +LEM domain [IPR003887] 0.709241221085716 1.721898836087479 0.0850878458694053 1.0 0.3139656722851695 6 Q86XL3,P42167,P50402 3 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7543862611470937 1.7063404272474514 0.0879447152233123 1.0 0.3164651528499117 5 P20020,P23634,P16615 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7543862611470937 1.7063404272474514 0.0879447152233123 1.0 0.3164651528499117 5 P20020,P23634,P16615 3 +Syntaxin 6, N-terminal [IPR015260] 0.9509444601071324 1.7012833668009637 0.0888897897975709 1.0 0.3182277237823409 2 O43752 1 +GOLD domain [IPR009038] 0.7042353064751103 1.698127522376588 0.0894836960707281 1.0 0.3191280793542805 6 Q15363,P49755 2 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.9461516774739218 1.6813647420539932 0.0926920895687217 1.0 0.3272405932818654 2 Q15418 1 +Peptidase M28 [IPR007484] 0.7957686882933814 1.6612805877603285 0.0966571068857615 1.0 0.3361359090206335 4 P02786,Q9NXS2,Q7Z2K6 3 +Prenylcysteine lyase [IPR010795] 0.9362841838173062 1.6403148395409195 0.1009397217195806 1.0 0.3423759714130024 2 Q9UHG3 1 +BRICHOS domain [IPR007084] 0.9286721172822124 1.608614546143743 0.1077006515611977 1.0 0.3509685568357914 2 Q9NQX7 1 +START domain [IPR002913] 0.922469692698057 1.5827665267331792 0.1134746887672366 1.0 0.3617733521017202 2 Q9NQZ5 1 +MENTAL domain [IPR019498] 0.9224696926980512 1.582766526733156 0.1134746887672419 1.0 0.3617733521017202 2 O95772 1 +Homeobox domain [IPR001356] 0.7745273852048522 1.570565576771566 0.1162835910452475 1.0 0.3667054556624499 4 Q96G23 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6249978473881809 1.563066292613165 0.1180370029338742 1.0 0.3680679279949171 7 P13674,Q32P28 2 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6249978473881809 1.563066292613165 0.1180370029338742 1.0 0.3680679279949171 7 P13674,Q32P28 2 +RNA recognition motif domain, eukaryote [IPR003954] 0.4923216410929026 1.4964177387520317 0.1345448298146654 1.0 0.3858331734992867 14 P38159,Q14011,Q14498,Q9UHX1 4 +CNNM, transmembrane domain [IPR002550] 0.8996334930927572 1.4875013121728606 0.1368824569127253 1.0 0.388183806896696 2 Q8NE01 1 +Ion transporter-like, CBS domain [IPR044751] 0.8996334930927572 1.4875013121728606 0.1368824569127253 1.0 0.388183806896696 2 Q8NE01 1 +MRH domain [IPR044865] 0.7493018965952618 1.46226531993283 0.1436685180361012 1.0 0.4004956893608565 4 P11717,Q13438 2 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8858190019735017 1.429839981862313 0.1527629509901427 1.0 0.411635403281424 2 Q9NVI7 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.8784888638285878 1.3992493374304498 0.1617382262147773 1.0 0.4274291876148556 2 P23634 1 +Glycosyltransferase 2-like [IPR001173] 0.6854995626046921 1.395486776464861 0.162869099665543 1.0 0.4288789695871827 5 Q8N4A0 1 +Major facilitator superfamily domain [IPR020846] 0.7301021641330396 1.3795215332170505 0.1677340117540913 1.0 0.4340499957956615 4 Q7L0J3,Q9H2V7 2 +Fatty acid hydroxylase [IPR006694] 0.8720045108542316 1.372197353526095 0.1700020090654641 1.0 0.435559020839747 2 Q15800 1 +Marvel domain [IPR008253] 0.8700310121229229 1.3639664891507792 0.1725781127886194 1.0 0.4374690873590027 2 Q16625 1 +Sterol-sensing domain [IPR000731] 0.8697490837327355 1.3627907555685703 0.1729484654238393 1.0 0.4380107874321149 2 O15118 1 +Dynamin, GTPase domain [IPR001401] 0.7224855369764899 1.3466445161569944 0.1780947496898339 1.0 0.444665042560572 4 O00429,O60313 2 +Diacylglycerol kinase, catalytic domain [IPR001206] 0.8593177332957441 1.319310829660725 0.1870652187756258 1.0 0.4520608052693604 2 Q53H12 1 +Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.4521317229264536 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.4521317229264536 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.4521317229264536 2 P05067 1 +Amyloidogenic glycoprotein, extracellular [IPR008154] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.4521317229264536 2 P05067 1 +Beta-amyloid precursor protein C-terminal [IPR019543] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.4521317229264536 2 P05067 1 +Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.4521317229264536 2 P05067 1 +Potentiating neddylation domain [IPR005176] 0.8562165210036535 1.3063943565627254 0.1914184840124517 1.0 0.453608300094523 2 Q9BTE7 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.8553707358331031 1.302872617325644 0.1926182538202587 1.0 0.4544768918274794 2 P51114 1 +ERAP1-like C-terminal domain [IPR024571] 0.7096684128090796 1.2912790633912905 0.196606927839241 1.0 0.4582579896451685 4 Q9NZ08 1 +Phospholipase D/Transphosphatidylase [IPR001736] 0.8522695235410129 1.2899632639777237 0.197063413313749 1.0 0.4582579896451685 2 Q8IV08 1 +Importin-beta, N-terminal domain [IPR001494] 0.4613663245753343 1.2831295819759094 0.1994466814061239 1.0 0.4595051389269641 14 P55060,Q8TEX9,Q92973,O15397,O95373,Q96P70 6 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.8556119571348 1.2762649407244702 0.2018618790869979 1.0 0.4595051389269641 3 P51114,Q06787 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.8556119571348 1.2762649407244702 0.2018618790869979 1.0 0.4595051389269641 3 P51114,Q06787 2 +Agenet-like domain [IPR008395] 0.8556119571348 1.2762649407244702 0.2018618790869979 1.0 0.4595051389269641 3 P51114,Q06787 2 +Fxr1, tudor domain [IPR041560] 0.8556119571348 1.2762649407244702 0.2018618790869979 1.0 0.4595051389269641 3 P51114,Q06787 2 +CBS domain [IPR000644] 0.5394743228754851 1.2702919262306247 0.203980663060213 1.0 0.4614319853692197 8 P54619,Q6P4Q7,P51790,P51797,Q8NE01 5 +EH domain [IPR000261] 0.6560383747178261 1.26122040263655 0.2072294497805122 1.0 0.4635308332690498 5 Q96D71,Q9H4M9,P42566,Q9H223 4 +Glycoside hydrolase 35, catalytic domain [IPR031330] 0.8446574570059082 1.2583041951851133 0.2082817645546937 1.0 0.4655122411630085 2 P16278 1 +Tim44-like domain [IPR007379] 0.8421201014942261 1.247760957930529 0.212118610285183 1.0 0.4707012971090253 2 O43615 1 +OCRE domain [IPR041591] 0.8391276773190062 1.2118149261948266 0.2255832333638578 1.0 0.4879717822078074 3 P52756 1 +Guanylate kinase-like domain [IPR008144] 0.528698133720428 1.2099071922837528 0.2263145070931518 1.0 0.4886296230366428 8 Q5T2T1,Q07157,Q9UDY2,Q8N3R9,Q14168 5 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.528698133720428 1.2099071922837528 0.2263145070931518 1.0 0.4886296230366428 8 Q5T2T1,Q07157,Q9UDY2,Q8N3R9,Q14168 5 +Choline/carnitine acyltransferase domain [IPR039551] 0.8328164646179725 1.2091514554343217 0.2266046638444174 1.0 0.4888785803310118 2 P23786 1 +Mu homology domain [IPR028565] 0.6890381354825914 1.2021394899841675 0.2293094885692093 1.0 0.4925604853896346 4 Q9BXS5 1 +GRIP domain [IPR000237] 0.8293759134252419 1.1737619933217724 0.2404903713116808 1.0 0.5036787102527788 3 Q15643 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.8237947561319465 1.171797717977708 0.241278279119169 1.0 0.5049506500128716 2 P13674 1 +Syntaxin, N-terminal domain [IPR006011] 0.8276931754089091 1.1672028188175474 0.2431284728296365 1.0 0.5057940550830832 3 Q86Y82,O15400 2 +Extracellular Endonuclease, subunit A [IPR020821] 0.8267265437401745 1.1634360141409037 0.244652644756754 1.0 0.508208614219825 3 O94919 1 +DNA/RNA non-specific endonuclease [IPR001604] 0.8267265437401745 1.1634360141409037 0.244652644756754 1.0 0.508208614219825 3 O94919 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8245910885504737 1.1551173010750495 0.2480423942330043 1.0 0.5098146101600581 3 P10321,P04439 2 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8245910885504737 1.1551173010750495 0.2480423942330043 1.0 0.5098146101600581 3 P10321,P04439 2 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8240270727580358 1.1529208272263127 0.2489428826226483 1.0 0.5098146101600581 3 P13674,Q32P28 2 +Legume-like lectin [IPR005052] 0.8184381167183534 1.1496656755521857 0.2502815968045699 1.0 0.5113819525188356 2 P49257 1 +Protein kinase, C-terminal [IPR017892] 0.5163775687221743 1.1408208604265535 0.253944477881981 1.0 0.5160092733706533 8 Q15418 1 +Post-SET domain [IPR003616] 0.6275588671447503 1.1312651476553228 0.2579435088389776 1.0 0.5196112648054361 5 O96028,Q9BZ95 2 +AP complex, mu/sigma subunit [IPR022775] 0.5427380270072975 1.1303720770119805 0.2583194749372866 1.0 0.5196112648054361 7 P61923,Q9Y2T2 2 +Ricin B, lectin domain [IPR000772] 0.6720801489903128 1.12895276522215 0.2589177600729218 1.0 0.5196112648054361 4 Q8N4A0 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.8127995489145801 1.1264112825543426 0.2599914733414896 1.0 0.5196112648054361 2 O00754 1 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.8127995489145801 1.1264112825543426 0.2599914733414896 1.0 0.5196112648054361 2 O00754 1 +Glycoside hydrolase family 38, central domain [IPR015341] 0.8127995489145801 1.1264112825543426 0.2599914733414896 1.0 0.5196112648054361 2 O00754 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8169768753524989 1.1254899302400354 0.2603814819338002 1.0 0.5196478397479696 3 Q96RQ1,Q9Y282 2 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8169768753524989 1.1254899302400354 0.2603814819338002 1.0 0.5196478397479696 3 Q96RQ1,Q9Y282 2 +Lamin tail domain [IPR001322] 0.8158488437676236 1.1211055514638122 0.2622429359199665 1.0 0.5207608301365244 3 Q03252,P20700 2 +EXPERA domain [IPR033118] 0.8085706230617422 1.1090016971255012 0.2674294498539871 1.0 0.5253461119477206 2 Q15125 1 +Complement Clr-like EGF domain [IPR026823] 0.8068790527206076 1.102045843323786 0.2704417419139528 1.0 0.5265704111360809 2 P98164 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.8093311798641973 1.0958001318031882 0.2731662508095243 1.0 0.5292951055186624 3 Q8N4A0 1 +PA domain [IPR003137] 0.8018043416971946 1.081207290726692 0.279604915638223 1.0 0.5354625644688161 2 Q8TCT8 1 +L27 domain [IPR004172] 0.6158307917253536 1.0778324848913194 0.2811085196850822 1.0 0.5366206962653439 5 Q14168,Q8N3R9,Q5T2T1 3 +L27 domain, C-terminal [IPR014775] 0.6158307917253536 1.0778324848913194 0.2811085196850822 1.0 0.5366206962653439 5 Q14168,Q8N3R9,Q5T2T1 3 +Immunoglobulin subtype 2 [IPR003598] 0.5028938954634739 1.06524757914083 0.2867639078301931 1.0 0.540014519680364 8 Q92859,P35613 2 +Fibronectin type II domain [IPR000562] 0.7972934874541677 1.0627228507154265 0.287907655060809 1.0 0.5406080939227202 2 Q9UBV2 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7919368480406004 1.040823559350293 0.2979574437754748 1.0 0.5468585112958689 2 O60506 1 +Zinc finger, CHHC-type [IPR012996] 0.7893401015228387 1.0185239064470055 0.3084290456557015 1.0 0.5542774919492992 3 P55795,P31943 2 +Peptidase S54, rhomboid domain [IPR022764] 0.7860163518466271 1.01668853324581 0.3093016223589229 1.0 0.5542774919492992 2 Q9H300 1 +Heat shock chaperonin-binding [IPR006636] 0.6456981664315935 1.015540492584911 0.3098482546197263 1.0 0.5542774919492992 4 P54727,Q9NRR5,P31948 3 +SUN coiled coil domain 2 [IPR040994] 0.7851705666760656 1.0132469681722651 0.3109422111984903 1.0 0.5555235926587725 2 Q9UH99 1 +WW domain [IPR001202] 0.4088015623060109 0.992730526983016 0.3208412940562257 1.0 0.5631338720534885 16 P46934 1 +Pleckstrin homology domain, spectrin-type [IPR001605] 0.7789681420919132 0.9880598070735516 0.3231233586402571 1.0 0.5649643185116119 2 O15020 1 +Pleckstrin homology domain 9 [IPR041681] 0.7789681420919132 0.9880598070735516 0.3231233586402571 1.0 0.5649643185116119 2 O15020 1 +BSD domain [IPR005607] 0.7807560900107292 0.98553284793605 0.3243624047314881 1.0 0.5661156576961553 3 Q9NW68 1 +PWWP domain [IPR000313] 0.4795101144101059 0.9799478971032278 0.3271118382908193 1.0 0.5698471650225114 10 Q7Z4V5,Q9BZ95 2 +LEM-like domain [IPR013146] 0.7747392162390687 0.9709408003104864 0.3315777592003557 1.0 0.575743820222347 2 P42167 1 +Fatty acid desaturase domain [IPR005804] 0.7654355793628418 0.9334467727779932 0.3505893403936475 1.0 0.5937297369719191 2 O60427 1 +EF-hand, Ca insensitive [IPR014837] 0.7667794698251584 0.9321174252024071 0.3512758436522443 1.0 0.5945322390143312 3 Q13813,O43707 2 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.7603608683394367 0.913100413827556 0.3611897327200246 1.0 0.6054475375810485 2 Q14011 1 +ABC1 atypical kinase-like domain [IPR004147] 0.7592331547786659 0.908589693440655 0.363566748956091 1.0 0.6079740610533675 2 Q96D53 1 +ADCK3-like domain [IPR034646] 0.7592331547786659 0.908589693440655 0.363566748956091 1.0 0.6079740610533675 2 Q96D53 1 +EGF-like domain [IPR000742] 0.5403618889733831 0.9058875530507148 0.3649953730796531 1.0 0.6096338489430766 6 P98164,Q08431 2 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.7566957992669907 0.8984552781454445 0.3689428774636658 1.0 0.6133717018130922 2 Q15067 1 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.7564138708767767 0.8973305080388047 0.3695425817979147 1.0 0.6133717018130922 2 Q9HCL2 1 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.7564138708767767 0.8973305080388047 0.3695425817979147 1.0 0.6133717018130922 2 Q9HCL2 1 +NOPS [IPR012975] 0.7549351381838647 0.8871912602531333 0.3749759369992196 1.0 0.6160004229434888 3 Q8WXF1,P23246 2 +Stromalin conservative domain [IPR020839] 0.753030730194534 0.8838536478300356 0.3767752217888438 1.0 0.6175049942096175 2 Q8WVM7 1 +STAG [IPR013721] 0.753030730194534 0.8838536478300356 0.3767752217888438 1.0 0.6175049942096175 2 Q8WVM7 1 +Exportin-2, central domain [IPR013713] 0.752890185425035 0.8794700764587864 0.3791464508767248 1.0 0.6195753808599197 3 O15397 1 +Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.7510572314631934 0.8760098949815115 0.381024654554146 1.0 0.6199251381365161 2 P06865 1 +Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.7510572314631934 0.8760098949815115 0.381024654554146 1.0 0.6199251381365161 2 P06865 1 +Band 3 cytoplasmic domain [IPR013769] 0.7507753030730009 0.8748904490938127 0.3816335163051145 1.0 0.6199251381365161 2 Q9Y6M7 1 +Bicarbonate transporter, C-terminal [IPR011531] 0.7507753030730009 0.8748904490938127 0.3816335163051145 1.0 0.6199251381365161 2 Q9Y6M7 1 +Immunoglobulin subtype [IPR003599] 0.4619203328849114 0.8738437174707866 0.3822033688230959 1.0 0.6199251381365161 9 Q92859,P35613 2 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.7504933746828105 0.8737712783333675 0.3822428248023439 1.0 0.6199251381365161 2 Q9BTY2 1 +IPT domain [IPR002909] 0.7493656611220609 0.8692973637858542 0.3846845044277056 1.0 0.6206450515752261 2 O15031 1 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.7493656611220607 0.869297363785853 0.3846845044277063 1.0 0.6206450515752261 2 Q9UID3 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.6064880112835016 0.8490538237278874 0.3958513431660586 1.0 0.627497815283132 4 P14625,P07900,P08238 3 +EH domain-containing protein, N-terminal [IPR031692] 0.7434451649281084 0.8458839671130971 0.3976174774185625 1.0 0.6285235791914274 2 Q9H4M9 1 +Domain of unknown function DUF5600 [IPR040990] 0.7434451649281084 0.8458839671130971 0.3976174774185625 1.0 0.6285235791914274 2 Q9H4M9 1 +Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.7423174513673348 0.8414389188631826 0.4001020901840997 1.0 0.6316687996356537 2 Q8NF37 1 +HDGF-related, PWWP domain [IPR035496] 0.5976581836810103 0.8120961708775827 0.4167364501901209 1.0 0.6469040729906904 4 Q7Z4V5 1 +Fzo/mitofusin HR2 domain [IPR006884] 0.7273752466873363 0.7830203456417851 0.4336151645373547 1.0 0.6617838428201113 2 Q8IWA4 1 +FCP1 homology domain [IPR004274] 0.7262475331265922 0.7786496831453745 0.4361861037267034 1.0 0.6639204698829306 2 Q05D32 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.7244782853919792 0.7734679986328922 0.4392454606527738 1.0 0.6660142668032297 3 Q9UL46,P61289 2 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.7244782853919792 0.7734679986328922 0.4392454606527738 1.0 0.6660142668032297 3 Q9UL46,P61289 2 +Thioredoxin domain [IPR013766] 0.3316594968448463 0.7653713686944199 0.4440504370306226 1.0 0.670018064522244 26 Q9H1E5,P07237,Q9P2K2,Q9H3N1,O43819,Q96JJ7,Q6ZRP7,Q9Y320,Q96J42,O95881 10 +CARG-binding factor, N-terminal [IPR012956] 0.7225824640541365 0.7644846451703389 0.4445784835801603 1.0 0.670018064522244 2 Q99729 1 +Peptidase M41 [IPR000642] 0.7217366788835622 0.7612245542072826 0.4465229546369689 1.0 0.670018064522244 2 Q96TA2 1 +Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.7154540327129106 0.740372995039935 0.4590737001706859 1.0 0.6734180035103458 3 O14874,Q15118 2 +Histidine kinase domain [IPR005467] 0.7154540327129106 0.740372995039935 0.4590737001706859 1.0 0.6734180035103458 3 O14874,Q15118 2 +Calcium uniporter protein, C-terminal [IPR006769] 0.7158161826895906 0.7384990896549078 0.4602112201602999 1.0 0.6734180035103458 2 Q9NWR8 1 +HECT domain [IPR000569] 0.412767748366135 0.6841453398130106 0.4938833939574185 1.0 0.6972165056593763 11 P46934 1 +Acyltransferase, C-terminal domain [IPR032098] 0.6976484757837856 0.6760491372971762 0.4990094480425551 1.0 0.7007686673666419 3 Q92604 1 +COP9 signalosome complex subunit 7, helix I [IPR041481] 0.699182407668457 0.6756111368958294 0.499287568767718 1.0 0.7008072501378212 2 Q9H9Q2 1 +Hook, C-terminal [IPR008636] 0.696363123766545 0.6651036704999588 0.5059841871490462 1.0 0.7035486021752884 2 Q96ED9 1 +HOOK, N-terminal [IPR043936] 0.696363123766545 0.6651036704999588 0.5059841871490462 1.0 0.7035486021752884 2 Q96ED9 1 +Chromo domain subgroup [IPR017984] 0.6944019299319669 0.664474070551926 0.5063869392068852 1.0 0.7035486021752884 3 P45973 1 +Chromo shadow domain [IPR008251] 0.6944019299319669 0.664474070551926 0.5063869392068852 1.0 0.7035486021752884 3 P45973 1 +EGF-like calcium-binding domain [IPR001881] 0.5611245371303992 0.6623273826173357 0.5077614315207377 1.0 0.7035486021752884 4 P98164 1 +F-BAR domain [IPR031160] 0.6907245559627875 0.6442304579916998 0.5194260029513149 1.0 0.709913942505926 2 Q96RU3 1 +FCH domain [IPR001060] 0.6907245559627875 0.6442304579916998 0.5194260029513149 1.0 0.709913942505926 2 Q96RU3 1 +Citron homology (CNH) domain [IPR001180] 0.6834191734176518 0.6257025876378578 0.5315100356847329 1.0 0.71503324854051 3 O95819 1 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.6805510571730112 0.6156805936363423 0.5381053479069717 1.0 0.7216031428047448 3 P16435 1 +Immunoglobulin I-set [IPR013098] 0.5458443471167163 0.6016209587713656 0.5474264744468818 1.0 0.7254244313013866 4 Q92859 1 +NSD, Cys-His rich domain [IPR041306] 0.6750284828688469 0.5965101549741076 0.5508344719271208 1.0 0.7278512209396171 3 Q9BZ95 1 +AWS domain [IPR006560] 0.6750284828688469 0.5965101549741076 0.5508344719271208 1.0 0.7278512209396171 3 Q9BZ95 1 +Fatty acyl-CoA reductase, C-terminal [IPR033640] 0.6740907809416463 0.5838362327309847 0.5593304985835688 1.0 0.7311304693967547 2 Q96K12 1 +Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120] 0.6740907809416463 0.5838362327309847 0.5593304985835688 1.0 0.7311304693967547 2 Q96K12 1 +Dynamin stalk domain [IPR000375] 0.6699097506311338 0.5788964777619654 0.5626590269800147 1.0 0.7320589294723691 3 O00429 1 +Dynamin GTPase effector [IPR003130] 0.6699097506311338 0.5788964777619654 0.5626590269800147 1.0 0.7320589294723691 3 O00429 1 +GTPase effector domain [IPR020850] 0.6699097506311338 0.5788964777619654 0.5626590269800147 1.0 0.7320589294723691 3 O00429 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.6640298836046461 0.5588560009649377 0.5762599996367266 1.0 0.738754222367853 3 Q9UGJ1 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.6640298836046461 0.5588560009649377 0.5762599996367266 1.0 0.738754222367853 3 Q9UGJ1 1 +Glycosyl transferase, family 1 [IPR001296] 0.6627185561195672 0.5544155361235762 0.5792944959637738 1.0 0.7402389061469558 3 Q2TAA5,Q9BT22 2 +GAR domain [IPR003108] 0.6656329292359782 0.5538626621726316 0.5796728398775026 1.0 0.7402389061469558 2 Q03001 1 +Glutathione S-transferase, N-terminal [IPR004045] 0.4083671569624084 0.5501314750648549 0.5822291997061255 1.0 0.7409707976232712 8 O15217,Q9H7Z7 2 +EB1, C-terminal [IPR004953] 0.6597124330420129 0.533200445309304 0.5938948333028762 1.0 0.7483235484068688 2 Q15691 1 +SLC12A transporter, C-terminal [IPR018491] 0.6563292923597488 0.5215167804666128 0.6020068190271772 1.0 0.7544766441180887 2 P55011 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.6563292923597488 0.5215167804666128 0.6020068190271772 1.0 0.7544766441180887 2 P55011 1 +Longin domain [IPR010908] 0.6528482797518471 0.5213466205048579 0.6021253295887112 1.0 0.7544766441180887 3 P51809,O15498 2 +v-SNARE, coiled-coil homology domain [IPR042855] 0.6528482797518471 0.5213466205048579 0.6021253295887112 1.0 0.7544766441180887 3 P51809,O15498 2 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.5246138326361653 0.5197470925276005 0.6032398594046442 1.0 0.7549949180373255 4 Q16134 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.6487046236943669 0.5076575606978838 0.6116935158608277 1.0 0.7631109666535846 3 Q9UEY8 1 +RecF/RecN/SMC, N-terminal [IPR003395] 0.4482077335591202 0.4810096428163331 0.6305096453621999 1.0 0.776030818253174 6 Q8IY18,Q9UQE7,Q9NTJ3,O95347,Q14683 5 +RasGAP protein, C-terminal [IPR000593] 0.6384658770445556 0.474353503243369 0.6352478441113565 1.0 0.7788562658197619 3 Q86VI3,Q13576 2 +NAD-dependent epimerase/dehydratase [IPR001509] 0.6363123766563368 0.4543549648246986 0.649573360942199 1.0 0.7841843054304142 2 Q9NRG7 1 +Ras GTPase-activating domain [IPR001936] 0.5042837298941185 0.444594527577017 0.6566128029411924 1.0 0.7867394744074467 4 Q86VI3,Q13576 2 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.6248305317926371 0.4312299830229236 0.6663011548736442 1.0 0.7914258674978597 3 Q5BKZ1 1 +Proteasome component (PCI) domain [IPR000717] 0.3177470937629169 0.4290769395282302 0.6678672336647373 1.0 0.7914258674978597 20 O00231,P60228,Q9UNS2,Q99627,Q9Y262,Q9BT78 6 +Cyclic nucleotide-binding domain [IPR000595] 0.4594452681250583 0.4060279431941459 0.6847220689472757 1.0 0.796042787848891 5 Q6P4Q7 1 +SWIRM domain [IPR007526] 0.4906229453712626 0.3961979596294789 0.6919589963994002 1.0 0.8011251983158273 4 Q8NB78 1 +Clp ATPase, C-terminal [IPR019489] 0.6171412461234936 0.3934941171476523 0.6939545681397727 1.0 0.8024387810251467 2 O76031 1 +LRRC8, pannexin-like TM region [IPR021040] 0.6162954609529248 0.3908936547025751 0.6958758443913018 1.0 0.803778016854396 2 Q8TDW0 1 +FF domain [IPR002713] 0.6094449256379582 0.3844069782949287 0.7006768291908796 1.0 0.8055478677704356 3 O75400 1 +14-3-3 domain [IPR023410] 0.416596104995761 0.3504330631815777 0.7260137167315803 1.0 0.8202057361328292 6 P63104,P61981,Q04917,P31946,P62258 5 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.4149036227012683 0.3437803484518116 0.7310114801409149 1.0 0.8210687480845452 6 P43243,Q12874,P09234 3 +PB1 domain [IPR000270] 0.5982520439808301 0.3372418735714546 0.7359345736935334 1.0 0.8233952724543492 2 Q92734 1 +SET domain [IPR001214] 0.3601884646986374 0.3350758995236463 0.7375678324275448 1.0 0.8235376099724978 9 Q03164,O96028,Q9BZ95 3 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.4120304095329343 0.3325744157755925 0.7394555582816549 1.0 0.8243691152135195 6 Q9NZ08 1 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.4120304095329343 0.3325744157755925 0.7394555582816549 1.0 0.8243691152135195 6 Q9NZ08 1 +AGC-kinase, C-terminal [IPR000961] 0.3242036766052152 0.3151257456793922 0.7526661814088602 1.0 0.8358604264087758 13 Q15418 1 +Histidine kinase/HSP90-like ATPase [IPR003594] 0.3507862293767777 0.2918571277501828 0.7703958640882775 1.0 0.8510576199094524 9 O14874,P07900,Q15118,Q15120,P14625 5 +Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.5816182689596963 0.2910530953310977 0.7710107121433123 1.0 0.8510690619993719 2 O75694 1 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.4561885794398802 0.2831698680626204 0.7770466252310846 1.0 0.8561755528724806 4 Q9UNH7,O60749 2 +Vps16, C-terminal [IPR006925] 0.5697772765717588 0.2602155494172899 0.7946975106057603 1.0 0.8706795609928315 2 Q9H9C1 1 +Rad60/SUMO-like domain [IPR022617] 0.5652664223287369 0.2489328142648039 0.8034127519769421 1.0 0.8790658603978497 2 Q8NCF5 1 +SUN domain [IPR012919] 0.5576361426040642 0.2434236994340013 0.8076771863640206 1.0 0.882824633727053 3 Q9UH99 1 +DnaJ domain [IPR001623] 0.2889023039855891 0.2328348767770189 0.8158896293382505 1.0 0.8894150868364806 20 Q96DA6,Q9UGP8,O60884,O75937,Q96KC8,Q9UBS4,Q96EY1,Q13217,Q9NVH1,Q8IXB1 10 +ERM family, FERM domain C-lobe [IPR041789] 0.5528951992478712 0.2319593668539759 0.8165695736442224 1.0 0.8894150868364806 3 P35241 1 +High mobility group box domain [IPR009071] 0.3038845928670374 0.1764399760917302 0.859948300886147 1.0 0.9237093543133568 12 O96028 1 +CTP synthase GATase domain [IPR033828] 0.5308711587256997 0.1717297031791277 0.8636500329475174 1.0 0.9259070138501758 2 Q9NRF8 1 +CTP synthase, N-terminal [IPR017456] 0.5308711587256997 0.1717297031791277 0.8636500329475174 1.0 0.9259070138501758 2 Q9NRF8 1 +Ribosomal protein S7 domain [IPR023798] 0.5303073019453223 0.1705974500064399 0.8645403031323053 1.0 0.9265062045066792 2 Q9Y2R9 1 +K Homology domain, type 1 [IPR004088] 0.2680193493958649 0.1635194664810811 0.8701094473918591 1.0 0.9299753334475716 23 P51116,P51114,P61978,Q96AE4,Q9Y6M1,Q06787,Q9Y2W6,Q96PU8 8 +Cobalamin (vitamin B12)-binding domain [IPR006158] 0.5257964477022941 0.1616968603849712 0.8715445770554067 1.0 0.930446215138189 2 Q99707 1 +STAMBP/STALP-like, MPN domain [IPR044098] 0.5238229489709785 0.157890983243942 0.874542703270403 1.0 0.9323930104765644 2 O95630 1 +FERM, N-terminal [IPR018979] 0.3345567476002317 0.1477307136153183 0.8825552916216064 1.0 0.9375473386679376 7 Q9HCM4,P15311,O43491,Q9Y2J2,P26038,P35241 6 +FERM, C-terminal PH-like domain [IPR018980] 0.3345567476002317 0.1477307136153183 0.8825552916216064 1.0 0.9375473386679376 7 Q9HCM4,P15311,O43491,Q9Y2J2,P26038,P35241 6 +Sec23, C-terminal [IPR037550] 0.5145193120947413 0.1406727063758688 0.888128507806172 1.0 0.9431094978450654 2 Q15436 1 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.310288591001791 0.1275050201804277 0.8985407000844639 1.0 0.9499637148075496 9 Q92905,O15372,O00303,P51665 4 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.3895627644569702 0.1102491495009305 0.9122117841489708 1.0 0.9592793805566072 4 P41240,P07947,Q15375 3 +Jumonji, helical domain [IPR041070] 0.4863264730758447 0.0957433871294193 0.9237243812135688 1.0 0.9680409932058242 2 Q9UPP1 1 +PDZ domain [IPR001478] 0.2496994534173328 0.0949614072481201 0.9243454809003442 1.0 0.9683289488937288 25 P57105,O00560,Q96L92,Q07157,Q13425,Q9UDY2,Q8N3R9,Q14168 8 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.4826830332942347 0.0941106488025136 0.92502126140614 1.0 0.9683343158373802 3 Q9BYT8 1 +Ubiquitin system component CUE [IPR003892] 0.3808180535966017 0.092703826317817 0.9261388571424948 1.0 0.969118355003898 4 Q9H4L7,Q9H0E2,Q9H1I8 3 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.2994726864195053 0.0905834979243975 0.9278235447667922 1.0 0.970155060272233 9 Q9BTU6 1 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.4796954314720881 0.0896121191264199 0.9285954534864342 1.0 0.9702365052122832 3 P23193,Q96QC0 2 +BRK domain [IPR006576] 0.4812517620524492 0.0887926505751003 0.9292466986123652 1.0 0.9705542657154178 2 P51532 1 +Fibronectin type III [IPR003961] 0.3126607333054748 0.0799183882785561 0.9363021648758648 1.0 0.975736434212791 7 Q92859,P10586 2 +K Homology domain [IPR004087] 0.2549534744338596 0.0656548406304208 0.9476526267500835 1.0 0.9849950722651426 22 P51116,P51114,P61978,Q96AE4,Q9Y6M1,Q06787,Q9Y2W6,Q96PU8 8 +ELMO domain [IPR006816] 0.4527769946433638 0.0558815891257654 0.9554361376579688 1.0 0.991839313018553 2 Q8IZ81 1 +Ubiquitin conjugation factor E4, core [IPR019474] 0.4524950662531811 0.0556051850966356 0.9556563337882624 1.0 0.991839313018553 2 O95155 1 +MPN domain [IPR037518] 0.2727460410916987 0.0546244348815724 0.956437671597558 1.0 0.9922819034459266 12 Q92905,O15372,P51665,Q15018 4 +Myosin tail [IPR002928] 0.3565585331452703 0.0505805269399809 0.9596597802107768 1.0 0.9938816214359988 4 P35579,P35580,Q7Z406 3 +RuvB-like, AAA-lid domain [IPR041048] 0.4465745700592136 0.05001253906127 0.9601123961010848 1.0 0.9938816214359988 2 Q9Y230 1 +TIP49, P-loop domain [IPR010339] 0.4465745700592136 0.05001253906127 0.9601123961010848 1.0 0.9938816214359988 2 Q9Y230 1 +SPRY-associated [IPR006574] 0.3321106094808017 0.0412194359660268 0.9671209591792408 1.0 0.9981802147896484 5 Q14258,P14373,Q12899,O15344 4 +Exportin-1/Importin-beta-like [IPR013598] 0.3495063469675575 0.0401208164133409 0.9679968060636196 1.0 0.998715523894421 4 O14980,Q9Y5L0,O43592 3 +Arf GTPase activating protein [IPR001164] 0.4283699943598436 0.029087641901383 0.9767946919628958 1.0 1.0 3 Q8N6T3,Q8N6H7 2 +Immunoglobulin V-set domain [IPR013106] 0.3410437235542969 0.0286021147585187 0.9771819254423664 1.0 1.0 4 Q9Y624,P15151,Q9BX67 3 +Dilute domain [IPR002710] 0.4121793064561607 0.0248761239801618 0.980153771643665 1.0 1.0 2 Q9Y4I1 1 +EYA domain [IPR006545] 0.4048491683112556 0.0209602969020949 0.9832773271941904 1.0 1.0 2 O95677 1 +EYA domain, metazoan [IPR042577] 0.4048491683112556 0.0209602969020949 0.9832773271941904 1.0 1.0 2 O95677 1 +SMARCC, C-terminal [IPR032451] 0.3972371017761548 0.0173559229787867 0.9861526722208518 1.0 1.0 2 Q8TAQ2 1 +SMARCC, N-terminal [IPR032450] 0.3972371017761548 0.0173559229787867 0.9861526722208518 1.0 1.0 2 Q8TAQ2 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.3972371017761548 0.0173559229787867 0.9861526722208518 1.0 1.0 2 Q8TAQ2 1 +Dynein heavy chain AAA lid domain [IPR041658] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, coiled coil stalk [IPR024743] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, AAA module D4 [IPR024317] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, ATP-binding dynein motor region [IPR035706] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain region D6 P-loop domain [IPR004273] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, C-terminal domain [IPR041228] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, tail [IPR013594] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, linker [IPR013602] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.4004512126339571 0.0081827252549791 0.993471202711947 1.0 1.0 3 Q9UBF8,O00443 2 +Sorting nexin, N-terminal [IPR005329] 0.3693261911474483 0.0075971714862931 0.9939383924750194 1.0 1.0 2 O60749 1 +Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.3679165491965024 0.007228318356367 0.9942326866052592 1.0 1.0 2 Q92538 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.3631237665632956 0.0060505132679867 0.9951724183338152 1.0 1.0 2 O15027 1 +p21 activated kinase binding domain [IPR033923] 0.3628418381731063 0.0059847893505776 0.9952248574833068 1.0 1.0 2 Q13177 1 +VHS domain [IPR002014] 0.3206770874519029 0.0053052047371557 0.9957670789044012 1.0 1.0 4 O14964 1 +BAG domain [IPR003103] 0.3942470389170985 0.004515456002035 0.996397199614118 1.0 1.0 3 Q9UL15,O95429 2 +PABP, RNA recognition motif 2 [IPR045305] 0.3439526360304491 0.0023803405559073 0.9981007648145066 1.0 1.0 2 P11940 1 +CD80-like, immunoglobulin C2-set [IPR013162] 0.3408514237383699 0.0019221102698273 0.9984663788358734 1.0 1.0 2 P15151 1 +Zinc finger, B-box, chordata [IPR020457] 0.3318297152523267 0.0007678705161032 0.9993873280307132 1.0 1.0 2 P14373 1 +Tudor domain [IPR002999] 0.2681842657510246 0.0006332227991336 0.9994947613387872 1.0 1.0 8 Q14739 1 +Ribosomal protein S4/S9, N-terminal [IPR001912] 0.3244995771074147 3.874622098458308e-06 0.9999969084988488 1.0 1.0 2 Q9NV31 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eb7e20d256162a3e7d1981e04bfc4411215c6b63 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, SH3 domain [IPR035723]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-activated protein kinase, glycogen-binding domain [IPR032640]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARIP4, DEXH-box helicase domain [IPR044573]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATF7-interacting protein , protein binding domain [IPR031870]", "ATM, catalytic domain [IPR044107]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin repeat and SOCS box protein 6, SOCS box domain [IPR037327]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Association with the SNF1 complex (ASC) domain [IPR006828]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related protein 13, N-terminal [IPR018731]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BTB/POZ domain-containing protein KCTD11/21, C-terminal domain [IPR045763]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CCZ1/INTU, second Longin domain [IPR043988]", "CCZ1/INTU/HPS4, third Longin domain [IPR043989]", "CCZ1/INTU/HSP4, first Longin domain [IPR043987]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, N-terminal [IPR013164]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Caudal-like activation domain [IPR006820]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centromere protein H, C-terminal [IPR008426]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Cortactin-binding protein-2, N-terminal [IPR019131]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-glucuronyl C5-epimerase, C-terminal [IPR010598]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIRP domain [IPR033471]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DTX3L, RING-HC finger [IPR042843]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Death effector domain [IPR001875]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deltex, C-terminal [IPR039396]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Deubiquitinating protein VCPIP1, N-terminal [IPR045827]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4706 [IPR031600]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephexin-1, SH3 domain [IPR035635]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin receptor-binding domain [IPR001799]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Ephrin-B ectodomain [IPR034255]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAK1/PYK2, FERM domain C-lobe [IPR041784]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHF complex subunit HOOK interacting protein, C-terminal [IPR045669]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focadhesin/RST, DUF3730 [IPR022542]", "Focal adhesion kinase, N-terminal [IPR041390]", "Focal adhesion kinase, targeting (FAT) domain [IPR005189]", "Folliculin, DENN domain [IPR032035]", "Folliculin/SMCR8, longin domain [IPR037520]", "Folliculin/SMCR8, tripartite DENN domain [IPR037521]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formin-binding protein 1, F-BAR domain [IPR037449]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HEPN domain [IPR007842]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock factor (HSF)-type, DNA-binding [IPR000232]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Interleukin-1 receptor-associated kinase 1, death domain [IPR035533]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intimal thickness related receptor, IRP [IPR019336]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Knl1, C-terminal RWD domain [IPR040850]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIN-9, C-terminal [IPR045831]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "LysM domain [IPR018392]", "Lysine-specific demethylase 4, Tudor domain [IPR040477]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M28 Zn-Peptidase Glutaminyl Cyclase [IPR037457]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MID domain of medPIWI [IPR041285]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTF2, PHD domain 1 [IPR042014]", "MTF2, PHD domain 2 [IPR042015]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex subunit Med13, C-terminal [IPR009401]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial ABC-transporter, N-terminal five TM domain [IPR032410]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "Mitogen-activated protein kinase kinase kinase, N-terminal [IPR045801]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFRKB winged helix-like domain [IPR025220]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neogenin, C-terminal [IPR010560]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Opioid growth factor receptor (OGFr) conserved domain [IPR006757]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain [IPR019601]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHLDB1/2/3, PH domain [IPR037810]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIGA, GPI anchor biosynthesis [IPR013234]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-beta, PH domain [IPR037862]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phosphoinositide-specific phospholipase C, EF-hand-like domain [IPR015359]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase C-beta, C-terminal domain [IPR014815]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polycomb-like MTF2 factor 2, C-terminal domain [IPR025894]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain [IPR039558]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Protocadherin [IPR013585]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Putative zinc-finger domain [IPR019607]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Rapamycin-insensitive companion of mTOR, N-terminal domain [IPR028267]", "Rapamycin-insensitive companion of mTOR, domain 4 [IPR029453]", "Rapamycin-insensitive companion of mTOR, domain 5 [IPR029452]", "Rapamycin-insensitive companion of mTOR, middle domain [IPR029451]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Riboflavin kinase domain, bacterial/eukaryotic [IPR015865]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SBF1/SBF2 domain [IPR022096]", "SCAN domain [IPR003309]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMG1, PIKK catalytic domain [IPR039414]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SOCS box domain [IPR001496]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-protein kinase SMG1, N-terminal [IPR035175]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Somatomedin B domain [IPR001212]", "Somatomedin B, chordata [IPR020436]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAFII55 protein, conserved region [IPR006751]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomere-length maintenance and DNA damage repair [IPR021668]", "Teneurin intracellular, N-terminal [IPR009471]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor Elf, N-terminal [IPR022084]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone C, N-terminal [IPR031925]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Unconventional myosin-Ie/If, SH3 domain [IPR035507]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP1, N-terminal [IPR040557]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate heat shock transcription factor, C-terminal domain [IPR010542]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZEF1, zinc finger, ZZ-type [IPR041986]", "ZZZ3, zinc finger, ZZ-type [IPR041981]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "APLP2", "APMAP", "APOBEC3C", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG2B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCKDHB", "BCKDK", "BCOR", "BCR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPHL", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf198", "C1orf35", "C2CD2", "C2CD5", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CBL", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDKAL1", "CDKN2AIP", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CENPH", "CEP170", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHTF18", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNPY2", "COA3", "COASY", "COIL", "COLEC12", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC27", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCTD", "DCTN1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDHD2", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM129B", "FAM160B2", "FAM208A", "FAM208B", "FAM49B", "FAM8A1", "FANCA", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO7", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR180", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPB11", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "IVD", "IWS1", "JAM3", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD3", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED25", "MEPCE", "METAP2", "METTL13", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MGME1", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCOS", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL24", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD6B", "OXA1L", "OXNAD1", "OXSM", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDXK", "PDZD8", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QPCTL", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMND1", "RNASEH2A", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RSL24D1", "RTCA", "RTF1", "RTFDC1", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBF1", "SC5D", "SCAF11", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STRN3", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEDC1", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOP1", "TOP2A", "TOP2B", "TP53", "TP53BP1", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TST", "TTC4", "TTC7B", "TTF2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UHRF1BP1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URB2", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VCPIP1", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS28", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YES1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF106", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ABRAXAS2", "ACOX1", "ACTN4", "ADD3", "AGK", "AGPAT5", "ALG1", "ALG11", "ANKLE2", "AP1M1", "AP3M1", "APP", "ARFGAP1", "ARFGAP2", "ASCC2", "ATAD3A", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "BAG4", "BAG5", "BCKDK", "BSDC1", "BSG", "CALU", "CBX5", "CD47", "CERS1", "CERS2", "CETN2", "CIRBP", "CLCN3", "CLCN6", "CLPX", "CNNM3", "CNNM4", "COPS3", "COPS4", "COPS5", "COPS7B", "COPS8", "COPZ1", "COQ8B", "CPT2", "CSE1L", "CSK", "CTDSPL2", "CTPS2", "CYB5B", "CYB5D2", "DCUN1D5", "DNAJA2", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC19", "DNAJC3", "DNAJC8", "DNM1L", "DNM2", "DST", "DYNC2H1", "EBP", "EFCAB14", "EHD1", "EHD4", "EIF3E", "EIF3F", "EIF3H", "EIF3L", "ELMOD2", "EMD", "ENDOD1", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPS15", "ERAP1", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ETFDH", "EYA4", "EZR", "F11R", "FADS1", "FAR2", "FCGRT", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP9", "FLOT1", "FMR1", "FNBP1", "FUBP1", "FUCA2", "FUS", "FXR1", "FXR2", "GALNT4", "GBF1", "GLB1", "GNPAT", "GPAM", "GSTA4", "HDGFL2", "HEXA", "HGS", "HLA-A", "HLA-B", "HLA-C", "HNRNPAB", "HNRNPH1", "HNRNPH2", "HNRNPK", "HOOK2", "HSP90AA1", "HSP90AB1", "HSP90B1", "IGF2BP2", "IGF2R", "IMP3", "INA", "IPO4", "IPO7", "IPO8", "IPO9", "IQGAP2", "IQGAP3", "ITM2C", "JAM3", "KDM1B", "KMT2A", "LBR", "LETM1", "LMAN1", "LMNB1", "LMNB2", "LPCAT1", "LPGAT1", "LRP2", "LRRC8C", "MAN2B1", "MAP4K4", "MAPRE1", "MATR3", "MCUB", "MFGE8", "MFN1", "MICU1", "MICU2", "MID1", "MPP2", "MPP5", "MPP7", "MRPS7", "MSMO1", "MSN", "MTR", "MYH10", "MYH14", "MYH9", "MYO5A", "NEDD4", "NEFL", "NEFM", "NEO1", "NFATC2IP", "NLN", "NPC1", "NSD2", "NSD3", "NUCB1", "NUCB2", "NUP155", "OCLN", "OPA1", "OS9", "P3H1", "P4HA1", "P4HB", "PABPC1", "PAK2", "PARL", "PCYOX1", "PDK1", "PDK3", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PHF8", "PI4K2A", "PI4KB", "PIK3C2A", "PLD3", "PLXNB2", "POR", "PPP1R10", "PRKAG1", "PRPF40A", "PSMD11", "PSMD7", "PSME2", "PSME3", "PSPC1", "PTGES2", "PTPRF", "PUF60", "PVR", "QKI", "QPCTL", "QSOX2", "RAD23B", "RBM10", "RBM39", "RBM5", "RBMX", "RCN2", "RDX", "REPS1", "RPS6KA1", "RTN3", "RUVBL2", "SCO2", "SDCBP", "SDF4", "SDR39U1", "SEC16A", "SEC23A", "SEC63", "SEL1L", "SF3A3", "SFPQ", "SLC12A2", "SLC25A12", "SLC25A24", "SLC4A7", "SMARCA4", "SMARCAD1", "SMARCC2", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SNAP29", "SNRPC", "SNTB2", "SNX2", "SNX27", "SNX6", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN2", "STAG1", "STAMBP", "STARD3NL", "STARD7", "STIP1", "STOM", "STOML2", "STX10", "STX12", "STX5", "STX6", "STX7", "SUN2", "SV2A", "SYNCRIP", "SYNJ2BP", "TAF15", "TAP1", "TCEA1", "TDRKH", "TFG", "TFRC", "TIMM10B", "TIMM44", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TLCD1", "TMED10", "TMED2", "TMPO", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOLLIP", "TRAM1", "TRIM25", "TRIM26", "TRIM27", "TRIP11", "TUBGCP4", "TXNDC12", "TXNDC15", "TXNDC16", "UBE4B", "UBQLN4", "VAMP7", "VIM", "VIPAS39", "VPS51", "XPO1", "XPOT", "YES1", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZMPSTE24", "ZNF326"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f85b20835c42b2ba8fcce3ae4af73125749ade51 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]", "2": "P-type ATPase [IPR001757]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1b4779d6076f860fab585a63348a2152a3a459ee --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bfb347db92aa97eaab9f915a713e12f367bc7a3a80e84dfcb9ef34af2bc8c3e1 +size 183785 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e156a8d21e18c9c7ed5dd91ef80e03185c00a175 --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f812adb56571ce4a828d7ce2b95a7ff4d9ed26eb86d5689ec4d7afeee42890df +size 177234 diff --git a/interpro_family/advanced/plot_2.png b/interpro_family/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..2b8687da5e9f0b61a4206a3455677ad0768470d8 --- /dev/null +++ b/interpro_family/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eac2f68fed00f2d1a90450db26cbbb9ee239292f4b53dfb222ba660b66a20bcc +size 181731 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bedfb0128f0e71b76ed2c2c5b3a06778c52efeae --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]", "2": "P-type ATPase [IPR001757]", "3": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "4": "14-3-3 protein [IPR000308]", "5": "Ezrin/radixin/moesin-like [IPR000798]", "6": "Small GTPase [IPR001806]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d8c5817e0eacc0df674e36a18906a52642b7e3fd --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d352731aca23549170ad8765f62cd2d1dfcd76e28bc2810a558c172d108dffa +size 136865 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8c912f4368141580d65409efd0cdba7233ac8897 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d3ce36daef576095592ffed8cd9ba558a3ac26b82f2544d6b4487558ad6fdf0 +size 133150 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..61058d3b27bcfa0123581cbdde9429590ec72363 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d081999b152f90e32a9142fdd952d992a913c069fddbd830bd1dc8d1df197002 +size 132169 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..8b2eed723db164eafecfc8ce761b6c5d374d7106 --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a82c4ab5b708354cd7bb0811472a15cdc1275bcca9ec0f199a4af9b54e368da2 +size 146436 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..5648422fc336687b973eed55d39fc86efea4c1d9 --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ecb9d3fe9ce8be6c6dec6ad70d3937c900fdce72c9c80237b4b3474871502d7 +size 134544 diff --git a/interpro_family/basic/plot_5.png b/interpro_family/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..1c3d9ec0261c34ecf413681b3d334ebee75010a1 --- /dev/null +++ b/interpro_family/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa4a03f45dbf760aa1faebff1897fae5fc0a824086a95bb92f33bd703772ce87 +size 138597 diff --git a/interpro_family/basic/plot_6.png b/interpro_family/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..8f9ce72e2b1c3c4456de0e1de9d6d424c775f397 --- /dev/null +++ b/interpro_family/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:472c664db800d4a9cb8cbeb34e34e6f93655a48431be0f48ef0ae1d488caa9a6 +size 150384 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d819ab7f80bd04464dd954fb2b7bf8580f9b8051 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:464b4c7e7b1a6fd72852f6d75dc7b88154d329d7ff025bf832eff2db273bae13 +size 438891 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b38a3495cdbfbcca5a46c0b3eeaf9a0f08f363f1 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 7 11 2.556738035282518 0.0105658753860697 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 2.511668512538341e-05 1.0 1.0 0.0834574734746242 2.7537597807274675e-05 +Syntaxin [IPR045242] 5 7 2.354354851576045 0.0185548886283983 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 0.0268788760081442 1.0 1.0 0.0439142352380576 0.0278921605814954 +P-type ATPase [IPR001757] 5 8 2.231514973742304 0.0256470367803576 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0192115706028201 1.0 1.0 0.4172977923286156 0.0201372619620155 +Type 1 protein exporter [IPR039421] 4 6 1.999553816629936 0.0455484651409383 1.4660194174757282 4.152912621359223 0.6118345866928353 0.3423864070958426 1.2012577064447347 1.3414295599134654 1.163285659538929 0.2820720534042253 0.3251899972986247 1.0 1.0 1.0 0.3290745839784397 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..de7609724167710a149301fcd80bd4da48d69268 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 2686, + "title": "Average number of proteins per term", + "value": 1.3019359642591213 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8d0ec4fd10c4429a8fe6623595cd2ffffd2eb27f --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b5e57d4c6aeae4da17436acb7bbaa8dcd21958ca --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,144 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier protein [IPR002067] 0.7327093773599362 2.556738035282518 0.0105658753860697 0.9999999999995934 0.0845537452503979 11 Q6NUK1,O75746,Q9HC21,P12236,Q9BQT8,P05141,P12235 7 +Syntaxin [IPR045242] 0.7825074453873208 2.354354851576045 0.0185548886283983 1.0 0.094673487323541 7 O43752,O60499,O15400,Q86Y82,Q13190 5 +P-type ATPase [IPR001757] 0.7167406340345546 2.231514973742304 0.0256470367803576 1.0 0.1082626560525543 8 Q9HD20,P16615,P20020,P23634,P05023 5 +Nucleosome assembly protein (NAP) [IPR002164] 0.8801502761841606 2.015875503490915 0.0438129957534625 1.0 0.1429911380240587 4 Q99733,Q01105 2 +Type 1 protein exporter [IPR039421] 0.7684930398786536 1.9995538166299356 0.0455484651409383 1.0 0.1468705610666991 6 Q9NP58,O75027,Q03518,P08183 4 +Eukaryotic porin/Tom40 [IPR027246] 0.8614935573254678 1.9383644582925104 0.0525787734026899 1.0 0.1592182473051015 4 P45880,P21796 2 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9954891457569772 1.885617484994496 0.0593465194570033 1.0 0.1719576604762792 2 O60830 1 +Palmitoyl protein thioesterase [IPR002472] 0.9949252889766 1.883294460099416 0.059660473782225 1.0 0.1724458140399703 2 P50897 1 +Haem oxygenase [IPR002051] 0.9935156470256552 1.8774856190009963 0.0604515665384903 1.0 0.1727841225073757 2 P09601 1 +Haem oxygenase-like [IPR016053] 0.9935156470256552 1.8774856190009963 0.0604515665384903 1.0 0.1727841225073757 2 P09601 1 +Tetraspanin, animals [IPR000301] 0.9785734423456428 1.8158035468507536 0.0694005130290955 1.0 0.1882927050466168 2 O43657 1 +Mitochondrial carrier UCP-like [IPR002030] 0.976318015224132 1.806476567476773 0.0708439311088624 1.0 0.1903953741610615 2 Q9H2D1 1 +ER lumen protein retaining receptor [IPR000133] 0.9760360868339416 1.805310404253048 0.0710261224532329 1.0 0.1903953741610615 2 P24390 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.8239774330042448 1.7809257637448948 0.0749245791040391 1.0 0.1974950142035811 4 Q6NUK4,Q9H6H4,Q9BRK0 3 +Tetraspanin/Peripherin [IPR018499] 0.9788494077834176 1.7574881333214545 0.078834642762549 1.0 0.202995139600042 3 Q9H1Z9,O43657 2 +Major facilitator superfamily [IPR011701] 0.7617081690501473 1.7390108418583563 0.0820328558817458 1.0 0.2076441305434117 5 Q7L0J3,Q96ES6,Q9H2V7 3 +Cleft lip and palate transmembrane 1 [IPR008429] 0.9596842402029886 1.7375681791458313 0.082286930857224 1.0 0.2076441305434117 2 Q96KA5 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.9596842402029886 1.7375681791458313 0.082286930857224 1.0 0.2076441305434117 2 Q96KA5 1 +AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752] 0.9568649563010964 1.7258689173389323 0.0843709977631594 1.0 0.2105728063895228 2 Q96ES6 1 +CD36 family [IPR002159] 0.9495348181561898 1.6954263891842931 0.0899945633681555 1.0 0.2193515401151233 2 Q14108 1 +Ribosomal protein S6 kinase II [IPR016239] 0.9461516774739218 1.6813647420539932 0.0926920895687217 1.0 0.2228438168345867 2 Q15418 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.7466805056672722 1.6718699315573038 0.0945499731660084 1.0 0.2257013563099004 5 Q15363,P49755 2 +Sulfotransferase [IPR005331] 0.9430504651818424 1.6684690455289937 0.0952226518132919 1.0 0.2267447187681756 2 Q7LGA3 1 +Cytochrome P450 [IPR001128] 0.9365661122074932 1.6414884018255609 0.1006960726940184 1.0 0.2356007415123115 2 Q6UW02 1 +Prenylcysteine oxidase [IPR017046] 0.9362841838173062 1.6403148395409195 0.1009397217195806 1.0 0.2357494800977451 2 Q9UHG3 1 +Derlin [IPR007599] 0.9360022554271228 1.639141238076515 0.1011838483818483 1.0 0.2359199798208721 2 Q9BUN8 1 +Porin, eukaryotic type [IPR001925] 0.9472645234066528 1.634795515860591 0.1020919211141566 1.0 0.2369763295734101 3 P45880,P21796 2 +Integral membrane protein 2 [IPR040145] 0.9286721172822124 1.608614546143743 0.1077006515611977 1.0 0.2437101517214635 2 Q9NQX7 1 +Nucleobindin [IPR040250] 0.9221877643078574 1.581591272879301 0.1137429075892679 1.0 0.2514513989998138 2 P80303 1 +Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708] 0.9207781223569202 1.5757145878165923 0.1150915940076733 1.0 0.2535980488142826 2 Q15070 1 +MICOS complex subunit MIC26/MIC27 [IPR019166] 0.9145756977727671 1.5498496089129403 0.121177616779619 1.0 0.2620636704267767 2 Q9BUR5 1 +MICOS complex subunit MIC26/MIC27, animal [IPR033182] 0.9145756977727671 1.5498496089129403 0.121177616779619 1.0 0.2620636704267767 2 Q9BUR5 1 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.4613296920523621 1.5090589483721886 0.1312837191166862 1.0 0.2757599961089752 19 Q06136,Q53GQ0,Q3SXM5,Q6YN16,Q9BY49,Q96LJ7,Q6UX07 7 +Ancient conserved domain protein family [IPR045095] 0.8996334930927572 1.4875013121728606 0.1368824569127253 1.0 0.2830570785301949 2 Q8NE01 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.8892021426557666 1.4439608310736685 0.1487499935869372 1.0 0.2990587445917015 2 P11279 1 +Mpv17/PMP22 [IPR007248] 0.8962490644234788 1.435430125592058 0.1511645665121488 1.0 0.3024170623655511 3 Q9NR77 1 +Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439] 0.886382858753868 1.432193395149428 0.1520884814444394 1.0 0.3034990053192899 2 Q96G23 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8858190019735017 1.429839981862313 0.1527629509901427 1.0 0.3043926456673021 2 Q9NVI7 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.8841274316323682 1.422779935696264 0.1547999595448148 1.0 0.3064058152817779 2 Q8IYU8 1 +Cytochrome c oxidase subunit VIIa, metazoa [IPR003177] 0.8810262193402769 1.4098374642543074 0.1585876814751103 1.0 0.3104712189811563 2 P14406 1 +Cytochrome c oxidase subunit VII [IPR039297] 0.8810262193402769 1.4098374642543074 0.1585876814751103 1.0 0.3104712189811563 2 P14406 1 +Zinc/iron permease [IPR003689] 0.8790527206089631 1.401602149634966 0.1610340847276898 1.0 0.3132060474862961 2 Q8N1S5 1 +P-type ATPase, subfamily IIB [IPR006408] 0.8784888638285878 1.3992493374304498 0.1617382262147773 1.0 0.3137774554933846 2 P23634 1 +Proteasome B-type subunit [IPR023333] 0.5898327010304312 1.3789785529454517 0.1679013665867532 1.0 0.3205742440417679 7 P49721,P28070,P28072 3 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.8773265651438182 1.361301546425903 0.1734184145040931 1.0 0.326649271639547 3 Q9Y5J9,O60220 2 +TAF15/EWS/TLS family [IPR034870] 0.8756345177665008 1.35467267330419 0.1755218680104042 1.0 0.328766902005541 3 Q92804,P35637 2 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.8674936566112226 1.353385894541712 0.1759323813174669 1.0 0.3288478609733584 2 Q93050 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.8674936566112226 1.353385894541712 0.1759323813174669 1.0 0.3288478609733584 2 Q93050 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.8750705019740528 1.3524630931262915 0.1762272176489787 1.0 0.3289411442704356 3 P12236,P12235 2 +Dynamin [IPR022812] 0.7224855369764899 1.3466445161569944 0.1780947496898339 1.0 0.3312759679133615 4 O00429,O60313 2 +Amyloidogenic glycoprotein [IPR008155] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.3426100736967962 2 P05067 1 +Defective-in-cullin neddylation protein [IPR014764] 0.8562165210036535 1.3063943565627254 0.1914184840124517 1.0 0.3444070504949634 2 Q9BTE7 1 +Aminopeptidase N-type [IPR034016] 0.7096684128090796 1.2912790633912905 0.196606927839241 1.0 0.3502539178573439 4 Q9NZ08 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.8556119571348 1.2762649407244702 0.2018618790869979 1.0 0.3566825664072013 3 P51114,Q06787 2 +Glycoside hydrolase, family 35 [IPR001944] 0.8446574570059082 1.2583041951851133 0.2082817645546937 1.0 0.3646967533206697 2 P16278 1 +Beta-galactosidase 1-like [IPR026283] 0.8446574570059082 1.2583041951851133 0.2082817645546937 1.0 0.3646967533206697 2 P16278 1 +Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591] 0.8412743163236583 1.2442477363988116 0.2134083996820193 1.0 0.3693397619697217 2 Q5H8A4 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.8384993938542339 1.2093613217912274 0.2265240613921706 1.0 0.382805111374909 3 Q9HB40 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.8328164646179725 1.2091514554343217 0.2266046638444174 1.0 0.382805111374909 2 P23786 1 +Stomatin/HflK/HflC family [IPR001972] 0.8314068226670304 1.2033089497802567 0.2288567870063778 1.0 0.384915046899894 2 P27105 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.8350253807106607 1.1957990237134213 0.2317749970114608 1.0 0.3883640935575695 3 Q5VW38,Q9NPR9 2 +Prolyl 4-hydroxylase [IPR045054] 0.8237947561319465 1.171797717977708 0.241278279119169 1.0 0.3985691621857859 2 P13674 1 +Nonaspanin (TM9SF) [IPR004240] 0.8262831359278006 1.1617083882025083 0.2453539372733346 1.0 0.402604990497565 3 Q99805,Q9HD45 2 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8169768753524989 1.1254899302400354 0.2603814819338002 1.0 0.4171402724417606 3 Q96RQ1,Q9Y282 2 +Peptidase C13, legumain [IPR001096] 0.8088525514519327 1.1101614589074842 0.2669294574412277 1.0 0.4244952769017986 2 Q99538 1 +HnRNP R/Q splicing factor [IPR006535] 0.7919368480406004 1.040823559350293 0.2979574437754748 1.0 0.4542075448245887 2 O60506 1 +Purine 5'-nucleotidase [IPR016695] 0.7893994925289005 1.0304707147734575 0.3027890926700625 1.0 0.4602668380938245 2 P49902 1 +Protein Yip1/4-like [IPR045231] 0.788835635748519 1.0281719448170197 0.3038689529245812 1.0 0.4615091535107711 2 Q9BSR8 1 +SUN domain-containing protein 1-5 [IPR045119] 0.7851705666760656 1.0132469681722651 0.3109422111984903 1.0 0.4676320152738774 2 Q9UH99 1 +Peptidase A22B, signal peptide peptidase [IPR007369] 0.7837609247251025 1.0075146554559042 0.3136875185822467 1.0 0.4699189486402202 2 Q8TCT8 1 +Presenilin/signal peptide peptidase [IPR006639] 0.7837609247251025 1.0075146554559042 0.3136875185822467 1.0 0.4699189486402202 2 Q8TCT8 1 +Spectrin, beta subunit [IPR016343] 0.7789681420919132 0.9880598070735516 0.3231233586402571 1.0 0.47766061712038 2 O15020 1 +Snf7 family [IPR005024] 0.5911147860013959 0.96567964709921 0.3342045069270898 1.0 0.4868973941341104 5 Q9HD42,Q9Y3E7,Q8WUX9 3 +Chloride channel, voltage gated [IPR001807] 0.7752397067117844 0.9644030270768122 0.3348439051826675 1.0 0.4869074307325492 3 P51797,P51790 2 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.7730476458979479 0.9641061215834952 0.3349927239276611 1.0 0.4869074307325492 2 O75880 1 +Copper chaperone SCO1/SenC [IPR003782] 0.7730476458979479 0.9641061215834952 0.3349927239276611 1.0 0.4869074307325492 2 O75880 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.7710741471666183 0.9561419773801916 0.3390005094041488 1.0 0.4911301878422566 2 Q9UM00 1 +Fatty acid desaturase [IPR012171] 0.7654355793628418 0.9334467727779932 0.3505893403936475 1.0 0.5019632027171308 2 O60427 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.7566957992669907 0.8984552781454445 0.3689428774636658 1.0 0.5210202780585733 2 Q15067 1 +Acyl-CoA oxidase [IPR012258] 0.7566957992669907 0.8984552781454445 0.3689428774636658 1.0 0.5210202780585733 2 Q15067 1 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.7564138708767767 0.8973305080388047 0.3695425817979147 1.0 0.5213189993220584 2 Q9HCL2 1 +Cohesin subunit Scc3/SA [IPR039662] 0.753030730194534 0.8838536478300356 0.3767752217888438 1.0 0.5270928363150179 2 Q8WVM7 1 +Beta-hexosaminidase [IPR025705] 0.7510572314631934 0.8760098949815115 0.381024654554146 1.0 0.5308708518195945 2 P06865 1 +Bicarbonate transporter, eukaryotic [IPR003020] 0.7507753030730009 0.8748904490938127 0.3816335163051145 1.0 0.5308708518195945 2 Q9Y6M7 1 +Glycoside hydrolase, family 29 [IPR000933] 0.7504933746828105 0.8737712783333675 0.3822428248023439 1.0 0.5308708518195945 2 Q9BTY2 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.7504933746828105 0.8737712783333675 0.3822428248023439 1.0 0.5308708518195945 2 Q9BTY2 1 +Sec1-like protein [IPR001619] 0.6112993808278903 0.8692901095762976 0.3846884712080762 1.0 0.5326150688994293 4 Q8WVM8 1 +Heat shock protein Hsp90 family [IPR001404] 0.6064880112835016 0.8490538237278874 0.3958513431660586 1.0 0.5400287763366005 4 P14625,P07900,P08238 3 +Mitofusin family [IPR027094] 0.7273752466873363 0.7830203456417851 0.4336151645373547 1.0 0.5745882249370176 2 Q8IWA4 1 +Proteasome activator PA28 [IPR009077] 0.7244782853919792 0.7734679986328922 0.4392454606527738 1.0 0.5790648925565938 3 Q9UL46,P61289 2 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.5865879814587867 0.7661322309127073 0.443597626847485 1.0 0.581221085713339 4 Q9NPH0 1 +Peptidase, FtsH [IPR005936] 0.7217366788835622 0.7612245542072826 0.4465229546369689 1.0 0.5830630316747197 2 Q96TA2 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.7205301748449062 0.7589510010028967 0.4478818684823475 1.0 0.5837024253971789 3 Q9UI14,O75915 2 +Importin beta family [IPR040122] 0.506694221873712 0.7456516773698288 0.4558778569582635 1.0 0.5903991917984069 6 Q8TEX9,Q92973 2 +PDK/BCKDK protein kinase [IPR039028] 0.7154540327129106 0.740372995039935 0.4590737001706859 1.0 0.5933936278433409 3 O14874,Q15118 2 +MCU family [IPR039055] 0.7158161826895906 0.7384990896549078 0.4602112201602999 1.0 0.5940064091064707 2 Q9NWR8 1 +Tricarboxylate/iron carrier [IPR004686] 0.7115059221658183 0.7259938180584393 0.4678425603227407 1.0 0.6000036707010807 3 Q6P4A7,Q9H9B4 2 +Tight junction protein ZO [IPR005417] 0.7042571186918539 0.6946390465126313 0.4872815357415581 1.0 0.6142859873919736 2 Q07157 1 +Clathrin adaptor, mu subunit [IPR001392] 0.6962655751612685 0.6711124900743058 0.5021488707670168 1.0 0.62558991970325 3 Q9BXS5 1 +Sorting nexin-5/6/32 [IPR014637] 0.691288412743165 0.6463090828468481 0.5180792067985618 1.0 0.6380379410641618 2 Q9UNH7 1 +THRAP3/BCLAF1 family [IPR029199] 0.6862137017197665 0.6276730428118746 0.5302181482082022 1.0 0.6441275197138088 2 Q9Y2W1 1 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.6839582745982573 0.6194430380553481 0.5356245361154941 1.0 0.6477656479091477 2 P05026 1 +Prohibitin [IPR000163] 0.6780377784042799 0.5979992012831623 0.5498404660237663 1.0 0.6581423759981445 2 Q99623 1 +Flotillin family [IPR027705] 0.6755004228925905 0.5888819541608886 0.5559404640758376 1.0 0.6616110263658396 2 O75955 1 +Fatty acyl-CoA reductase [IPR026055] 0.6740907809416463 0.5838362327309847 0.5593304985835688 1.0 0.6638805652653406 2 Q96K12 1 +Gamma-tubulin complex component protein [IPR007259] 0.6640298836046461 0.5588560009649377 0.5762599996367266 1.0 0.6735571623256081 3 Q9UGJ1 1 +Microtubule-associated protein RP/EB [IPR027328] 0.6597124330420129 0.533200445309304 0.5938948333028762 1.0 0.6825851614255565 2 Q15691 1 +SLC12A transporter family [IPR004842] 0.6563292923597488 0.5215167804666128 0.6020068190271772 1.0 0.6889605095470805 2 P55011 1 +Synaptobrevin [IPR001388] 0.6526642232872909 0.5089638708195073 0.6107775487640099 1.0 0.6951476677881909 2 P51809 1 +Prefoldin beta-like [IPR002777] 0.6472030674586596 0.50272635090215 0.615156680439803 1.0 0.6980611929283105 3 O15212 1 +YTH domain containing protein [IPR045168] 0.6405413025091603 0.4682514249797809 0.6396048009734985 1.0 0.7104956556719673 2 Q7Z739 1 +KH domain-containing BBP-like [IPR045071] 0.6339537507050184 0.4599227494206949 0.6455716704516274 1.0 0.7148955551167138 3 Q15637,Q96PU8 2 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.6248305317926371 0.4312299830229236 0.6663011548736442 1.0 0.7275731410493058 3 Q5BKZ1 1 +RNA-binding protein 26/27 [IPR045137] 0.6157316041725469 0.3891641395475907 0.6971547291084397 1.0 0.7410596254697415 2 Q9P2N5 1 +14-3-3 protein [IPR000308] 0.416596104995761 0.3504330631815777 0.7260137167315803 1.0 0.7587887767163353 6 P63104,P61981,Q04917,P31946,P62258 5 +Oxysterol-binding protein [IPR000648] 0.4157185741287966 0.3469789720779783 0.728607116386206 1.0 0.760901522011411 6 Q9H1P3,Q9BXB4,Q9BZF1,Q96SU4 4 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.4120304095329343 0.3325744157755925 0.7394555582816549 1.0 0.7689421717168118 6 Q9NZ08 1 +ClpA/B family [IPR001270] 0.5895122638849848 0.3125659816253124 0.7546104266988054 1.0 0.7831853192090383 2 Q9H078 1 +Structural maintenance of chromosomes protein [IPR024704] 0.4575458392101406 0.2873547441922827 0.7738407094322344 1.0 0.8015951197589594 4 Q9UQE7,Q9NTJ3,O95347 3 +Tropomodulin [IPR004934] 0.5799266986185496 0.2865412958018245 0.7744635692751638 1.0 0.8019310513003431 2 Q9NYL9 1 +Ezrin/radixin/moesin [IPR011174] 0.5528951992478712 0.2319593668539759 0.8165695736442224 1.0 0.841960028717229 3 P35241 1 +Glutathione Transferase family [IPR040079] 0.3330071117601277 0.2122460035530433 0.8319151185596871 1.0 0.8571246676069504 10 O15217,Q13505 2 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.3263524732717136 0.1850487892737297 0.8531907680292417 1.0 0.8756860538504178 10 Q9NR31,Q8N8L6 2 +H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504] 0.5334085142373974 0.1768788596528466 0.8596035443395575 1.0 0.8815941657487788 2 Q9NY12 1 +CTP synthase [IPR004468] 0.5308711587256997 0.1717297031791277 0.8636500329475174 1.0 0.8854061024797831 2 Q9NRF8 1 +Ribosomal protein S5/S7 [IPR000235] 0.5303073019453223 0.1705974500064399 0.8645403031323053 1.0 0.8859806387689325 2 Q9Y2R9 1 +Tropomyosin [IPR000533] 0.516873125715816 0.1535885554815673 0.8779341612661482 1.0 0.8969688692129609 3 P09493 1 +Phosphatidylinositol transfer protein [IPR001666] 0.519312094727955 0.1493935614940033 0.881243091904522 1.0 0.9000072033671278 2 Q00169 1 +Ezrin/radixin/moesin-like [IPR000798] 0.3345567476002317 0.1477307136153183 0.8825552916216064 1.0 0.9010047560986828 7 Q9HCM4,P15311,O43491,Q9Y2J2,P26038,P35241 6 +Protein transport protein Sec23 [IPR037364] 0.5145193120947413 0.1406727063758688 0.888128507806172 1.0 0.9063499893493078 2 Q15436 1 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.504715180898474 0.1307499814449841 0.8959730922202422 1.0 0.9136612474197306 3 P49902 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.5057795319988803 0.125584850900601 0.9000605552349166 1.0 0.9164376995303206 2 P84085 1 +Desmosomal cadherin [IPR009122] 0.5049337468283175 0.1241804424328527 0.901172407045931 1.0 0.917222086140724 2 Q14574 1 +Peptidase M3A/M3B [IPR045090] 0.4826830332942347 0.0941106488025136 0.92502126140614 1.0 0.938672534528793 3 Q9BYT8 1 +Ubiquitin conjugation factor E4 [IPR045132] 0.4524950662531811 0.0556051850966356 0.9556563337882624 1.0 0.9664506447873767 2 O95155 1 +RuvB-like [IPR027238] 0.4465745700592136 0.05001253906127 0.9601123961010848 1.0 0.9702264469253248 2 Q9Y230 1 +Eyes absent family [IPR028472] 0.4048491683112556 0.0209602969020949 0.9832773271941904 1.0 0.9891696257841182 2 O95677 1 +Exocyst complex component EXOC6/Sec15 [IPR007225] 0.3986467437270996 0.0179894778961282 0.9856472474767242 1.0 0.991182518428484 2 Q8TAG9 1 +Small GTPase [IPR001806] 0.2375635517003265 0.0093319249685774 0.9925543092129364 1.0 0.9962634060336124 34 Q9BZG1,P61026,Q9H0U4,P62820,P11233,Q13637,Q969Q5,P61019 8 +Phosphatidylinositol kinase [IPR015433] 0.4004512126339571 0.0081827252549791 0.993471202711947 1.0 0.9968112254330554 3 Q9UBF8,O00443 2 +Molecular chaperone regulator BAG [IPR039773] 0.3942470389170985 0.004515456002035 0.996397199614118 1.0 0.998627939613254 3 Q9UL15,O95429 2 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.3439526360304491 0.0023803405559073 0.9981007648145066 1.0 0.9999621985422472 2 P11940 1 +Ribosomal protein S4/S9 [IPR022801] 0.3244995771074147 3.874622098458308e-06 0.9999969084988488 1.0 1.0 2 Q9NV31 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6548ec5adb6a949a2fdb147a0758f954faab21e9 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [IPR028381]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit beta [IPR039160]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter A [IPR026082]", "ABC transporter Tap-like [IPR013305]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase subunit s, mitochondrial [IPR026063]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette sub-family D member 1 [IPR031237]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase ARIP4-like [IPR044574]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abr/Bcr [IPR037769]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin filament-associated protein 1 [IPR029907]", "Actin-filament associated protein [IPR030113]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating transcription factor 7-interacting protein [IPR026085]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Ankyrin repeat domain-containing protein 13 [IPR021832]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arv1 protein [IPR007290]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Atypical kinase COQ8B [IPR034638]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 13 [IPR040182]", "Autophagy-related protein 2 [IPR026849]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-ketoacyl synthase [IPR000794]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biogenesis of lysosome-related organelles complex 1 subunit 1 [IPR009395]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Caspase-8 [IPR033170]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein H [IPR040034]", "Centromere protein I [IPR012485]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-6 [IPR002248]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 1 [IPR033370]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein COX14 [IPR029208]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "D-glucuronyl C5-epimerase [IPR039721]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XPF [IPR006167]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deltex family [IPR039398]", "DeoC/FbaB/LacD aldolase [IPR002915]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyribose-phosphate aldolase [IPR011343]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Deubiquitinating protein VCPIP1 [IPR039087]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1 [IPR027741]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 SUMO-protein ligase PIAS2 [IPR027228]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase Praja-2 [IPR030639]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase synoviolin/Hrd1 [IPR032832]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [IPR029890]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin [IPR031328]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 3 [IPR028479]", "Eyes absent homologue 4 [IPR028478]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FHF complex subunit HOOK interacting protein [IPR019384]", "FUN14 [IPR007014]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Focadhesin [IPR021392]", "Focadhesin/RST1 [IPR045163]", "Folliculin [IPR021713]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1 [IPR028532]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutaminyl-peptide cyclotransferase-like [IPR040234]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 4 [IPR000715]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Heat shock transcription factor family [IPR027725]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Histidine acid phosphatase, VIP1 family [IPR037446]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hyccin [IPR018619]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Interleukin-1 receptor-associated kinase 1 [IPR035536]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 25 [IPR033558]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "Junctional adhesion molecule C [IPR042974]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF15/KIN-12E [IPR044986]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore scaffold 1 [IPR037388]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICAL-like protein [IPR028563]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med20 [IPR013921]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit TOM6 homologue [IPR029182]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor sulfurase [IPR028886]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 5 [IPR030574]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [IPR033197]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "NURS complex subunit red1 [IPR039278]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Neogenin [IPR033024]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor related to kappa-B-binding protein [IPR024867]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "OPI10 family [IPR031318]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Opioid growth factor receptor [IPR039574]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Osteopetrosis-associated transmembrane protein 1 precursor [IPR019172]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, Tysnd1 [IPR017345]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisomal/glyoxysomal leader peptide-processing protease [IPR039245]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol N-acetylglucosaminyltransferase subunit PIG-A/GPI3 [IPR039507]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta [IPR016280]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pianissimo family [IPR028268]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM8A1 [IPR039871]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LIN-9/Protein ALWAYS EARLY [IPR010561]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein Nucling [IPR030227]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4559 [IPR027897]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein zyg-11 homologue B [IPR040367]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Purine-rich element-binding protein beta [IPR030499]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cap guanine-N2 methyltransferase [IPR019012]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II subunit A [IPR006811]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 33 [IPR039878]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Rab29/Rab38/Rab32 [IPR030697]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Refilin family [IPR028215]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Riboflavin kinase [IPR023468]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease H2, subunit C [IPR013924]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose 5-phosphate isomerase, type A [IPR004788]", "Ribose-5-phosphate isomerase, type A, subgroup [IPR020672]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNARE associated Golgi protein [IPR032816]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase ATM/Tel1 [IPR015519]", "Serine/threonine-protein kinase Atg1-like [IPR045269]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase SMG1 [IPR031559]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase TOUSLED-like 2 [IPR027086]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Spindle assembly checkpoint component Mad1 [IPR008672]", "Spindlin-1 [IPR029565]", "Spindlin/spermiogenesis-specific protein [IPR003671]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA-Box binding protein-like [IPR015445]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TATA-box binding protein [IPR000814]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex subunit 7/Mft1 [IPR008501]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TMEM9/TMEM9B [IPR008853]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "Target of Myb1-like 2 [IPR027429]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription initiation factor TFIID subunit 7 [IPR037817]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 41A/B [IPR045014]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone C [IPR027684]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase [IPR033895]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1-binding protein 1-like [IPR026728]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiE/COQ5 methyltransferase [IPR004033]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0489 [IPR024131]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family UPF0729 [IPR026776]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar (H+)-ATPase G subunit [IPR005124]", "Vacuolar fusion protein Ccz1 [IPR013176]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR48/Bun107 [IPR021772]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "ZZ-type zinc finger-containing protein 3 [IPR037830]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger ZZ-type and EF-hand domain-containing protein 1 [IPR040099]", "Zinc finger protein 106 [IPR042622]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc finger protein-like 1 [IPR039043]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-specific 2-thiouridylase [IPR004506]", "von Willebrand factor A domain-containing protein 8 [IPR039891]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANKRD13A", "ANKS1A", "ANO10", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEX1", "API5", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC6", "ARMC8", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATF7IP", "ATG13", "ATG2B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN2L", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCLAF1", "BCR", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRI3BP", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf35", "C2CD2", "C2CD5", "C5orf22", "C5orf51", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CENPF", "CENPH", "CENPI", "CENPK", "CEP170", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG1", "COG3", "COG5", "COG7", "COIL", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD2", "EFNB1", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM160B2", "FAM162A", "FAM177A1", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNTB", "FOCAD", "FOXC1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMFB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "IPO4", "IPO5", "IQCB1", "IRAK1", "IRGQ", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "JAGN1", "JAM3", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KNL1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LRRFIP1", "LSG1", "LSM12", "LSM2", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL16", "METTL3", "METTL9", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST2", "MGST3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NEO1", "NES", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDE2", "NRM", "NSA2", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAK2", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM33", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO4", "RFC1", "RFK", "RFLNB", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOX1", "RIOX2", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBF1", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLK", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPIN1", "SPNS1", "SPPL2A", "SPR", "SPRYD7", "SPTBN1", "SPTBN2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "SYVN1", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL2", "TBPL1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEDC1", "TEFM", "TENM3", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TLE3", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM41A", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBR4", "UBR7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UHRF1BP1", "ULK3", "UMPS", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VTA1", "VWA8", "WAPL", "WARS", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR12", "WDR18", "WDR4", "WDR41", "WDR46", "WDR48", "WDR73", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H7A", "ZC3H7B", "ZCCHC3", "ZFC3H1", "ZFPL1", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF106", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCB6", "ABCB7", "ACOX1", "ACP6", "AP1M1", "APOO", "APP", "ARF5", "ARL10", "ARL6IP5", "ATAD3A", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP6V0A1", "BAG4", "BAG5", "BCKDK", "CERS2", "CHMP1A", "CHMP3", "CHMP7", "CLCN3", "CLCN6", "CLPB", "CLPTM1L", "CNNM3", "COX7A2", "CPT2", "CTPS2", "CYP20A1", "DCUN1D5", "DERL1", "DHRS1", "DHRS13", "DNM1L", "DSC3", "EPB41L2", "EPB41L3", "EPB41L5", "ERAP1", "ERGIC2", "ERGIC3", "EXOC6", "EYA4", "EZR", "FADS1", "FAR2", "FLOT1", "FMR1", "FUCA2", "FUS", "FXR1", "GAR1", "GLB1", "GPAM", "GPR107", "GPR108", "GSTA4", "HEXA", "HMOX1", "HS2ST1", "HSD17B12", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "IMP3", "IPO4", "ITM2C", "KDELR1", "KDSR", "LAMP1", "LGMN", "MAPRE1", "MCUB", "MFN1", "MFSD3", "MICU2", "MRPS7", "MSN", "MTX1", "NAP1L4", "NLN", "NT5C2", "NUCB2", "OPA1", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OXA1L", "P4HA1", "PABPC1", "PCYOX1", "PDK1", "PECR", "PFDN6", "PHB2", "PI4KB", "PIGG", "PIK3C2A", "PITPNA", "PPT1", "PSMB2", "PSMB4", "PSMB6", "PSME2", "PSME3", "PXMP2", "QKI", "RAB10", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB32", "RAB34", "RABAC1", "RALA", "RBM27", "RDX", "REEP2", "REEP3", "REEP4", "RPS6KA1", "RUVBL2", "SAR1A", "SCARB2", "SCFD1", "SCO1", "SCPEP1", "SEC23A", "SET", "SF1", "SFXN1", "SFXN4", "SLC12A2", "SLC25A12", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC39A11", "SLC4A7", "SMC2", "SMC3", "SMC4", "SNX6", "SPNS1", "SPPL2A", "SPTBN2", "STAG1", "STOM", "STX10", "STX12", "STX5", "STX6", "STX7", "SUN2", "SV2A", "SYNCRIP", "TAF15", "TAP1", "THRAP3", "TIMM17B", "TIMM8A", "TIMM8B", "TJP1", "TM9SF2", "TM9SF3", "TMCO1", "TMED10", "TMED2", "TMOD3", "TNPO1", "TPM1", "TSPAN10", "TSPAN6", "TUBGCP4", "UBE4B", "VAMP7", "VDAC1", "VDAC2", "YIPF4", "YME1L1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZNF326"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..59485a8e3e5164e5d61c514fd44db6aabea69bd6 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Glycoside hydrolase superfamily [IPR017853]", "2": "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "3": "SNARE [IPR010989]", "4": "Immunoglobulin-like domain superfamily [IPR036179]", "5": "EF-hand domain pair [IPR011992]", "6": "P-type ATPase, transmembrane domain superfamily [IPR023298]", "7": "P-type ATPase, A domain superfamily [IPR008250]", "8": "P-type ATPase, cytoplasmic domain N [IPR023299]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/plot_0.png b/interpro_homologous_superfamily/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e46a6ae4ab5278dde5705cec098b57e2c0121dfe --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dcdef51841c5c6d2b71a235853e6a55fde4ca4c97048efc2cf08dec43fa9c351 +size 193895 diff --git a/interpro_homologous_superfamily/advanced/plot_1.png b/interpro_homologous_superfamily/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a1aac398d73906e2fc8f8c47b30f99aad4807d30 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:77b3a75d949f2c39feeb73bdc971c831b098c77df1330e7fdfe44e4b9086e7b6 +size 194556 diff --git a/interpro_homologous_superfamily/advanced/plot_2.png b/interpro_homologous_superfamily/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..90f3854db765a71ea5bd3678fc9ec5deb66736f4 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d72bfc8b7db8cc0149e639469f88826139e0122b47d404fc7af8f65e7ed8cd6 +size 193093 diff --git a/interpro_homologous_superfamily/advanced/plot_3.png b/interpro_homologous_superfamily/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..219923dcb2841c94a65c1da197e7dc05cca2d855 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fc0aa49a6a24a294861b1fdad74c9e3d005d0e3ffd2805b24ad4a96e0a6d80a +size 178867 diff --git a/interpro_homologous_superfamily/advanced/plot_4.png b/interpro_homologous_superfamily/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..d1b9157b6cc14fa4e9be8371dc49de024a957afe --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e71b5c5fe7cfd5a8922a7326da1e661976def797cdac2becc90f5dcaaafae129 +size 194000 diff --git a/interpro_homologous_superfamily/advanced/plot_5.png b/interpro_homologous_superfamily/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..abee40c7fe764a6c2862bcb704ea6fce79044cb6 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:026804b66c8650cee01e56eacfc1ce91d057eec5542ab75315bd96f10a341862 +size 207789 diff --git a/interpro_homologous_superfamily/advanced/plot_6.png b/interpro_homologous_superfamily/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..e508556fd717c326bec110bed43f232cf995ca48 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2058c8ed02f7b17b74634416f60d0dcbc50ab5fa049b9ddabe60fee899db2dc6 +size 189839 diff --git a/interpro_homologous_superfamily/advanced/plot_7.png b/interpro_homologous_superfamily/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..7504003bd4aaf06773dc07f0f4c663df52a6d4de --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cfa1135c9f6f350acbcda314f761260da1ff7fe69c61502c12269393cdbe7596 +size 187774 diff --git a/interpro_homologous_superfamily/advanced/plot_8.png b/interpro_homologous_superfamily/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..414a4b15d997d13cf768f8b7053534e2c512154e --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2aa5f43ce608c439998ab7b2cae375c0d3fcc5300826816af0a8876ebfe71c1c +size 188851 diff --git a/interpro_homologous_superfamily/basic/idx2term.json b/interpro_homologous_superfamily/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a2e93c6d4cac3a861d410291cead06de488077a9 --- /dev/null +++ b/interpro_homologous_superfamily/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Glycoside hydrolase superfamily [IPR017853]", "2": "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "3": "SNARE [IPR010989]", "4": "Immunoglobulin-like domain superfamily [IPR036179]", "5": "EF-hand domain pair [IPR011992]", "6": "P-type ATPase, transmembrane domain superfamily [IPR023298]", "7": "P-type ATPase, A domain superfamily [IPR008250]", "8": "P-type ATPase, cytoplasmic domain N [IPR023299]", "9": "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "10": "Band 7/SPFH domain superfamily [IPR036013]", "11": "MFS transporter superfamily [IPR036259]", "12": "Immunoglobulin-like fold [IPR013783]", "13": "Alpha/Beta hydrolase fold [IPR029058]", "14": "Longin-like domain superfamily [IPR011012]", "15": "HAD-like superfamily [IPR036412]", "16": "HAD superfamily [IPR023214]", "17": "Nucleotide-diphospho-sugar transferases [IPR029044]", "18": "SH3-like domain superfamily [IPR036028]", "19": "14-3-3 domain superfamily [IPR036815]", "20": "Chaperone J-domain superfamily [IPR036869]", "21": "PDZ superfamily [IPR036034]", "22": "Thioredoxin-like superfamily [IPR036249]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/basic/plot_0.png b/interpro_homologous_superfamily/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c546bb0a8b51c3a7f1e97929bf723b87ae61e91c --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5801314c2ed85b2a3fb3ea0ada9a731042f98b63ef20a993b18263b1be8b9cca +size 147548 diff --git a/interpro_homologous_superfamily/basic/plot_1.png b/interpro_homologous_superfamily/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f03f0d09bccd1ee3206bc88bf184450df0b9c4ff --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6e702513b877b94f57d8f006beef5ddf3ae4818055100478fe61bceae1e0ede4 +size 134550 diff --git a/interpro_homologous_superfamily/basic/plot_10.png b/interpro_homologous_superfamily/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..bd18879592ac2a4e790c25adeb613a768913db25 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c866805638e003908c49acaaba849456c72d1157947b813e89aec07d117d00ec +size 134815 diff --git a/interpro_homologous_superfamily/basic/plot_11.png b/interpro_homologous_superfamily/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..225b4df08e0024f740dd3d39a3acdc88b79ee639 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2183555c27e09f4bed6ad70e499f3a8ce5daddd6fc30038ebd7cfdd5c2480d38 +size 136788 diff --git a/interpro_homologous_superfamily/basic/plot_12.png b/interpro_homologous_superfamily/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..ea5ab4063f3bcdcddfb2d02a42f0e582d4732674 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f0be527b15b2c396ab791dfe4b97c80f15ef6016db40873b2e43be03a1f886f +size 142829 diff --git a/interpro_homologous_superfamily/basic/plot_13.png b/interpro_homologous_superfamily/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..12fbfe1891a0118a3f0bf13c3802a1444e0cfa66 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9798713edf01fc3d036d4febbb10cd59fa3fa3ddedeeae3c0b5b1fe2f68a531a +size 142398 diff --git a/interpro_homologous_superfamily/basic/plot_14.png b/interpro_homologous_superfamily/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..af549f468e459df51313073de3f046109b7a1806 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:317f5a210321dd758a06c66654fb56cbd35fca7e84a0c18b5261b6c15930be3e +size 138867 diff --git a/interpro_homologous_superfamily/basic/plot_15.png b/interpro_homologous_superfamily/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..227357e34fef7523acd2e50d9774b186ac4fba3e --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0409e9251bca1b52bfafea3705e5ec2f0c82d0fc110c87c1d57886bc27e6afe5 +size 138757 diff --git a/interpro_homologous_superfamily/basic/plot_16.png b/interpro_homologous_superfamily/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..0e8a2f2150621f2706f525817619dde3ac1eb3ec --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1500c0f0e62c990c04b5b89546339f2a93e8c57b3bf0efef2f17bb1e7133bb50 +size 137315 diff --git a/interpro_homologous_superfamily/basic/plot_17.png b/interpro_homologous_superfamily/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..ad476e81a23d64c183f226580a41d2b83c0b675f --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:443ef04a70ea3338582fdcd71bf83632fd541b0bb82c331a2d2e8d26dc3b0448 +size 158451 diff --git a/interpro_homologous_superfamily/basic/plot_18.png b/interpro_homologous_superfamily/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..4c1d3a519618c8e27c11db181f59dcb9185a37c1 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2fbaa623aee15cec09329d2d56bca25268f660ef10114b8a066df4ee99dc15c1 +size 150741 diff --git a/interpro_homologous_superfamily/basic/plot_19.png b/interpro_homologous_superfamily/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..bc67c02cb010b15d59792ade4d1b7f62301e4f08 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bc93f1f552153cb331e9d80f9fa96045f612b283ac643d27adccefdc84230503 +size 140322 diff --git a/interpro_homologous_superfamily/basic/plot_2.png b/interpro_homologous_superfamily/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ae24240e7ec8b4b491765a8a8719b6d08b3744eb --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab97b8615f8ede9873c1d454a69daf754f017a912744d496e435b990fca1fa8b +size 130036 diff --git a/interpro_homologous_superfamily/basic/plot_20.png b/interpro_homologous_superfamily/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..6335e05f8040d0eb4ff514996a0cf138d1c118f9 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:734a02491f65c556cbdfd48a2a7a556d2700dab13b7bdb4158f3836149731847 +size 156207 diff --git a/interpro_homologous_superfamily/basic/plot_21.png b/interpro_homologous_superfamily/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..763bd3e4d2be5a4c139e89c4805441a1c63a2caf --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d66fd5e34e6eb5c6231683369b4c64a1f5544e8ecc03adc7bfa7e9923b0c904a +size 166315 diff --git a/interpro_homologous_superfamily/basic/plot_22.png b/interpro_homologous_superfamily/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..2f02c073825104f258d0c742dd10e2d3e4effeda --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:092cc6d540065c574b8b80dbd355fa8bac3af434a3d0d9022b1bedbd04435475 +size 150326 diff --git a/interpro_homologous_superfamily/basic/plot_3.png b/interpro_homologous_superfamily/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..ee4ac28ef39b86afd3c247ce769c644cf92eeab8 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:127fe7f4a505d88700e2461d559495d358ad718cc5028b31b6cd6492e637ed5a +size 131207 diff --git a/interpro_homologous_superfamily/basic/plot_4.png b/interpro_homologous_superfamily/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..53a8dfc224dcba26c951892a500a454ae0496105 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dde52128a414d7b164527bfc3cd3361bacda513ac7a6c9cd8dfdbecd8f7d0caf +size 144631 diff --git a/interpro_homologous_superfamily/basic/plot_5.png b/interpro_homologous_superfamily/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..5fb59ce1910ba71d127d5fdbc33fae02d9014fc5 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bed66a7ac22bd7d75b62d66f7d4b94ac61a454e3f58646ec33a0f4481ea94563 +size 134334 diff --git a/interpro_homologous_superfamily/basic/plot_6.png b/interpro_homologous_superfamily/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..ef215cde19c872f3559da3ac2b14c71d88418e26 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7646ee54a8ae46ea7725d53a2b2b4628b3d467e8644304673ac24c446423eeaf +size 143222 diff --git a/interpro_homologous_superfamily/basic/plot_7.png b/interpro_homologous_superfamily/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..21f9783230f9fe9789c8668f0a83d9ec28680bfc --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bdc0b6f7a7d139c9ab117eca2eac48bbe58811b45a2dbc8edde0901141b958c2 +size 141302 diff --git a/interpro_homologous_superfamily/basic/plot_8.png b/interpro_homologous_superfamily/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..4685152bb579a16a257511c1351f7ccb70e6ddcf --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7684847a31c8ad9feb89f5011e9ddc3279d777ee777fdc44c0bb5d367a826ca1 +size 141147 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..4954b5649ca1c5568ea3ba2a5a37c36b048f6c1a --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e9ece2ce9dcb52963de8bdcae4121fdb0cc8aae21e278631ba37da4436b0ae6 +size 143894 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..72cc232ce6b63b68941629ca6fa1eb324ec43d6c --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d968dbb8f0a07f5d6535eb3034de56f6b7c1f9fe319c96c1d997731d1238d8cc +size 165527 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..697053e66184b1a570bd5d2e71fee257ba483549 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,12 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 14 21 3.777538800238275 0.0001583858356473 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.0903515335443376e-08 0.1644315705571846 0.0513963234576887 2.9874917190946567e-05 1.2929972163241432e-08 +Glycoside hydrolase superfamily [IPR017853] 8 16 2.831653646509355 0.0046307979293682 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 1.919735629626428e-05 1.0 0.2223047329091382 0.000347389598862 2.128341707780042e-05 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 8 11 2.6355715794228343 0.0083995707862485 2.3689320388349513 6.349514563106796 0.6640264147492347 0.3307390797434538 1.7803691733569 2.1393617497725477 1.1694677427725269 0.279101120079799 0.0324301480805536 1.0 1.0 0.0498779046475234 0.0336357980244025 +SNARE [IPR010989] 6 7 2.573979789974912 0.0100536145607981 2.4854368932038833 5.364077669902913 0.7966086592831925 0.3585374753437345 1.5079985943563208 1.7302199405020957 1.098385457365192 0.3157194502762394 0.0059987647490075 1.0 1.0 0.0561137872346343 0.00630824692371 +Immunoglobulin-like domain superfamily [IPR036179] 7 14 2.563421821228955 0.0103646039892386 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.4763452627046071 0.4205819691215787 0.6727295364723632 0.530532682082201 0.4902330534772647 +EF-hand domain pair [IPR011992] 19 56 2.332640725493064 0.0196670095926507 13.3252427184466 49.37378640776699 0.9065364020670126 0.4404331516970506 4.9772339658485505 4.730718887980642 1.169914018421813 0.3730081256676846 3.330882899308418e-05 0.4528520674656749 0.0074800485008838 0.0010137918168685 4.016096444642775e-05 +Zinc finger, RanBP2-type superfamily [IPR036443] 4 9 2.3313809804091536 0.0197332795257649 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0026687375683324 1.0 1.0 1.0 0.0028394369313259 +P-type ATPase, transmembrane domain superfamily [IPR023298] 5 8 2.231514973742304 0.0256470367803576 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.022397770973718 1.0 1.0 0.4314443861210575 0.0234644839392777 +P-type ATPase, A domain superfamily [IPR008250] 5 8 2.231514973742304 0.0256470367803576 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0192115706028201 1.0 1.0 0.4172977923286156 0.0201372619620155 +P-type ATPase, cytoplasmic domain N [IPR023299] 5 8 2.231514973742304 0.0256470367803576 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0192115706028201 1.0 1.0 0.4172977923286156 0.0201372619620155 +Glycosyl hydrolase, all-beta [IPR013780] 4 8 2.0979062206545027 0.035913430396794 3.628640776699029 7.919902912621359 0.108448733903935 0.2677010542317815 1.6191976609214136 0.9906808437954988 1.5895506376095985 0.2857304479214345 0.0026425445039808 1.0 0.1180585699575878 0.0382400085743442 0.0027834726260547 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..64660a9e21502bede03a7c2050be3dcec1728044 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 1016, + "title": "Average number of proteins per term", + "value": 5.091535433070866 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9e67acba75206afaf878f48e064f930d097ae3fe --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..155cd4777261cdf078e39b029bf0bd74d3c66e55 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,133 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.7577332926540346 3.777538800238275 0.0001583858356473 0.1486506810567525 0.1181437786356038 21 Q6NUK1,Q9Y619,O75746,Q9BSK2,Q9HC21,Q9NZJ7,P12236,Q9H2D1,Q70HW3,Q9UBX3,Q9Y6C9,Q9BQT8,P05141,P12235 14 +Glycoside hydrolase superfamily [IPR017853] 0.6753979374556189 2.831653646509355 0.0046307979293682 0.9910474613917624 0.1181437786356038 16 P08236,P10253,P04062,P54802,Q9BTY2,P06865,P06280,P16278 8 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.7473100797535308 2.6355715794228343 0.0083995707862485 0.9998102886225962 0.1181437786356038 11 P33897,Q9NP58,O75027,Q03518,O14678,P08183,P33527,O15439 8 +SNARE [IPR010989] 0.8286278938452823 2.573979789974912 0.0100536145607981 0.9999652094700848 0.1181437786356038 7 O43752,O14653,O60499,O15400,Q86Y82,Q13190 6 +Immunoglobulin-like domain superfamily [IPR036179] 0.6554526804628584 2.563421821228955 0.0103646039892386 0.9999747172849244 0.1183195241917582 14 Q08722,P55899,P01889,P10321,P04439,Q92859,P35613 7 +EF-hand domain pair [IPR011992] 0.4785948141836751 2.332640725493064 0.0196670095926507 0.9999999982797334 0.1544019066113012 56 Q96D71,P80303,Q02818,Q9BPX6,Q8IYU8,Q8NF37,Q14257,O95202,O75746,P41208,Q9Y680,Q9NWM8,O95302,Q6NUK1,Q9BRK5,Q99584,Q96AY3,O75071,O43852 19 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.7235286585269693 2.3313809804091536 0.0197332795257649 0.9999999983939208 0.1544019066113012 9 P52756,Q92804,P98175,P35637 4 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7167406340345546 2.231514973742304 0.0256470367803576 0.9999999999965662 0.1725654925088963 8 Q9HD20,P16615,P20020,P23634,P05023 5 +P-type ATPase, A domain superfamily [IPR008250] 0.7167406340345546 2.231514973742304 0.0256470367803576 0.9999999999965662 0.1725654925088963 8 Q9HD20,P16615,P20020,P23634,P05023 5 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7167406340345546 2.231514973742304 0.0256470367803576 0.9999999999965662 0.1725654925088963 8 Q9HD20,P16615,P20020,P23634,P05023 5 +Glycosyl hydrolase, all-beta [IPR013780] 0.6911619855749127 2.0979062206545027 0.035913430396794 1.0 0.2109135565499582 8 O00754,P06280,P10253,Q9BTY2 4 +NAP-like superfamily [IPR037231] 0.8801502761841606 2.015875503490915 0.0438129957534625 1.0 0.2355238290239044 4 Q99733,Q01105 2 +Tim10-like domain superfamily [IPR035427] 0.8775740479548734 2.005204583530777 0.0449411802821715 1.0 0.2390588438046402 4 Q9Y5J9,O60220,Q9Y5J6 3 +Porin domain superfamily [IPR023614] 0.8614935573254678 1.9383644582925104 0.0525787734026899 1.0 0.2581468140451789 4 P45880,P21796 2 +START-like domain superfamily [IPR023393] 0.8036014207576815 1.9242622416247352 0.0543217208861999 1.0 0.2640711407673641 5 Q9NQZ5 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.9935156470256552 1.8774856190009963 0.0604515665384903 1.0 0.2752155113423613 2 P09601 1 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.6459821832942673 1.8572882539773217 0.0632701546406961 1.0 0.279916273290949 8 O43169,O15173,O00264,Q8WUJ1,O60427 5 +Band 7/SPFH domain superfamily [IPR036013] 0.6764539808017911 1.8282032864623696 0.0675190479772724 1.0 0.2915055841316649 7 Q99623,Q9UJZ1,P27105,P35232,O94905,O75955 6 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.486534201820608 1.8253092622099525 0.0679543732510219 1.0 0.2915055841316649 21 Q9UHG3,Q96CU9,Q16134,Q8NBM8 4 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.7714446952595758 1.7823253316483445 0.0746961940915 1.0 0.3011560841149368 5 P01889,P10321,P04439,P55899 4 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.7714446952595758 1.7823253316483445 0.0746961940915 1.0 0.3011560841149368 5 P01889,P10321,P04439,P55899 4 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9788494077834176 1.7574881333214545 0.078834642762549 1.0 0.3116575760573923 3 Q9H1Z9,O43657 2 +LEM/LEM-like domain superfamily [IPR011015] 0.709241221085716 1.721898836087479 0.0850878458694053 1.0 0.3258444457546198 6 Q86XL3,P42167,P50402 3 +Rhomboid-like superfamily [IPR035952] 0.7515047594827311 1.693460792892015 0.0903677916849947 1.0 0.3303034404061724 5 Q9GZP9,Q9BUN8,Q9H300 3 +Cytochrome P450 superfamily [IPR036396] 0.9365661122074932 1.6414884018255609 0.1006960726940184 1.0 0.3547467129300826 2 Q6UW02 1 +Galactose mutarotase-like domain superfamily [IPR011013] 0.7100420485695327 1.5068637530004387 0.1318455840645618 1.0 0.4162115003843275 5 O00754,P10253 2 +WW domain superfamily [IPR036020] 0.5058249297302869 1.4725307254303628 0.1408776161922302 1.0 0.4239845978894976 13 P46934 1 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.7493018965952618 1.46226531993283 0.1436685180361012 1.0 0.4280563469931931 4 P11717,Q13438 2 +MFS transporter superfamily [IPR036259] 0.5579226191486701 1.4339931587237105 0.1515742151535239 1.0 0.4425270189539665 10 Q7L0J3,Q16625,O00400,Q96ES6,Q9H2V7 5 +Cytochrome c oxidase, subunit VIIa superfamily [IPR036539] 0.8810262193402769 1.4098374642543074 0.1585876814751103 1.0 0.4525985516255959 2 P14406 1 +Immunoglobulin-like fold [IPR013783] 0.3832229768194061 1.3922316377216786 0.1638522651943041 1.0 0.4611465413778755 34 Q08722,P08236,O15031,P55899,P01889,P10321,P04439,Q8IZA0,Q92859,P10586,P35613 11 +E2 domain superfamily [IPR036176] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.472816101528339 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.472816101528339 2 P05067 1 +Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.472816101528339 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880] 0.8579080913448018 1.313439055616042 0.1890350443852018 1.0 0.472816101528339 2 P05067 1 +DCN1-like, PONY binding domain [IPR042460] 0.8562165210036535 1.3063943565627254 0.1914184840124517 1.0 0.472816101528339 2 Q9BTE7 1 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.8415115623237417 1.2211267762462912 0.2220380229864944 1.0 0.5032596275482726 3 P15586,Q5H8A4 2 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.8328164646179725 1.2091514554343217 0.2266046638444174 1.0 0.5071152829645994 2 P23786 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.6890381354825914 1.2021394899841675 0.2293094885692093 1.0 0.5120405283215751 4 Q9BXS5 1 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.8329895972872854 1.1878552869597814 0.2348904281726658 1.0 0.514763980608912 3 Q53H12 1 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.8329895972872854 1.1878552869597814 0.2348904281726658 1.0 0.514763980608912 3 Q53H12 1 +Peptidase S1, PA clan [IPR009003] 0.8226670425711708 1.1671352600640803 0.2431557503928816 1.0 0.5185867930805544 2 Q7KZN9 1 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.549544900313417 1.1663564109938802 0.2434703743104571 1.0 0.5185867930805544 7 O60476 1 +His-Me finger superfamily [IPR044925] 0.8267265437401745 1.1634360141409037 0.244652644756754 1.0 0.5189292005696495 3 O94919 1 +DNA/RNA non-specific endonuclease superfamily [IPR044929] 0.8267265437401745 1.1634360141409037 0.244652644756754 1.0 0.5189292005696495 3 O94919 1 +Alpha/Beta hydrolase fold [IPR029058] 0.3693904959914878 1.127800601010016 0.2594041395174447 1.0 0.5366826420298865 27 P42785,Q8NCC3,Q9HB40,P50897,Q9UMR5,Q9H6V9,P10619 7 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.8127995489145801 1.1264112825543426 0.2599914733414896 1.0 0.5366826420298865 2 O00754 1 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.8127995489145801 1.1264112825543426 0.2599914733414896 1.0 0.5366826420298865 2 O00754 1 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.8127995489145801 1.1264112825543426 0.2599914733414896 1.0 0.5366826420298865 2 O00754 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.8127995489145801 1.1264112825543426 0.2599914733414896 1.0 0.5366826420298865 2 O00754 1 +Lamin tail domain superfamily [IPR036415] 0.8158488437676236 1.1211055514638122 0.2622429359199665 1.0 0.5393498439163683 3 Q03252,P20700 2 +Ricin B-like lectins [IPR035992] 0.8093311798641973 1.0958001318031882 0.2731662508095243 1.0 0.5452591568221545 3 Q8N4A0 1 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 0.6625652012401702 1.0879679207698314 0.2766092695420106 1.0 0.5488965192474273 4 P98164,Q07954 2 +GOLD domain superfamily [IPR036598] 0.660445070305149 1.0788464409382017 0.280656188106136 1.0 0.5535004961241153 4 Q15363 1 +L27 domain superfamily [IPR036892] 0.6158307917253536 1.0778324848913194 0.2811085196850822 1.0 0.5535004961241153 5 Q14168,Q8N3R9,Q5T2T1 3 +Kringle-like fold [IPR013806] 0.7972934874541677 1.0627228507154265 0.287907655060809 1.0 0.5572221975009922 2 Q9UBV2 1 +Fibronectin type II domain superfamily [IPR036943] 0.7972934874541677 1.0627228507154265 0.287907655060809 1.0 0.5572221975009922 2 Q9UBV2 1 +Longin-like domain superfamily [IPR011012] 0.4552214633639953 1.046871923540449 0.2951586526473844 1.0 0.5632062507892595 12 Q9BXS5,Q9Y2T2,P51809,P53680,O15498,P61923 6 +Prefoldin [IPR009053] 0.5686437562084845 1.0426212204165737 0.2971237571513196 1.0 0.5642574528331604 6 Q9UBK9,Q9UHV9,O15212 3 +BSD domain superfamily [IPR035925] 0.7807560900107292 0.98553284793605 0.3243624047314881 1.0 0.5905998801061659 3 Q9NW68 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.7771662949970565 0.9717758725030968 0.3311620614991986 1.0 0.5976947136850774 3 P54802 1 +Chloride channel, core [IPR014743] 0.7752397067117844 0.9644030270768122 0.3348439051826675 1.0 0.5992219770914726 3 P51797,P51790 2 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.6134025125972667 0.8781557980530098 0.3798591758361014 1.0 0.647117812944273 4 P42892,Q9BYT8 2 +Phosphotransferase/anion transporter [IPR016152] 0.7507753030730009 0.8748904490938127 0.3816335163051145 1.0 0.647117812944273 2 Q9Y6M7 1 +Sec1-like superfamily [IPR036045] 0.6112993808278903 0.8692901095762976 0.3846884712080762 1.0 0.647117812944273 4 Q8WVM8 1 +Sec1-like, domain 2 [IPR027482] 0.6112993808278903 0.8692901095762976 0.3846884712080762 1.0 0.647117812944273 4 Q8WVM8 1 +Sec1-like, domain 3a [IPR043127] 0.6112993808278903 0.8692901095762976 0.3846884712080762 1.0 0.647117812944273 4 Q8WVM8 1 +Sec1-like, domain 1 [IPR043154] 0.6112993808278903 0.8692901095762976 0.3846884712080762 1.0 0.647117812944273 4 Q8WVM8 1 +HSP90, C-terminal domain [IPR037196] 0.6064880112835016 0.8490538237278874 0.3958513431660586 1.0 0.6497954870320143 4 P14625,P07900,P08238 3 +LDL receptor-like superfamily [IPR036055] 0.605724789582991 0.845849870380087 0.3976365007234159 1.0 0.6514342574273482 4 P98164,Q07954 2 +Homeobox-like domain superfamily [IPR009057] 0.3653764939325103 0.8347981593442415 0.4038313624070637 1.0 0.6554195913827104 21 Q96KC8,Q8N5B7,Q96G23 3 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.5161917778876547 0.790461245018582 0.4292584468305382 1.0 0.6791079413584032 6 Q13423 1 +Histidine phosphatase superfamily [IPR029033] 0.4747592599755149 0.7742571307605131 0.4387787493965678 1.0 0.6835021200839261 7 Q9NQ88,Q9NPH0 2 +Proteasome activator superfamily [IPR036252] 0.7244782853919792 0.7734679986328922 0.4392454606527738 1.0 0.6835021200839261 3 Q9UL46,P61289 2 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.7244782853919792 0.7734679986328922 0.4392454606527738 1.0 0.6835021200839261 3 Q9UL46,P61289 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.7244782853919792 0.7734679986328922 0.4392454606527738 1.0 0.6835021200839261 3 Q9UL46,P61289 2 +Peptidase M41-like [IPR037219] 0.7217366788835622 0.7612245542072826 0.4465229546369689 1.0 0.6835021200839261 2 Q96TA2 1 +Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784] 0.7154540327129106 0.740372995039935 0.4590737001706859 1.0 0.6888244327184483 3 O14874,Q15118 2 +HAD-like superfamily [IPR036412] 0.3446908675437157 0.7109681040358156 0.4771040013236811 1.0 0.7045605600942733 22 Q9HD20,P16615,P49902,Q04656,Q05D32,Q969T7,P20020,P23634,P05023 9 +HAD superfamily [IPR023214] 0.3446908675437157 0.7109681040358156 0.4771040013236811 1.0 0.7045605600942733 22 Q9HD20,P16615,P49902,Q04656,Q05D32,Q969T7,P20020,P23634,P05023 9 +HECT, E3 ligase catalytic domain [IPR035983] 0.412767748366135 0.6841453398130106 0.4938833939574185 1.0 0.7155107447426984 11 P46934 1 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.6957992669861796 0.6630077636173822 0.5073255818396496 1.0 0.7239365044228708 2 O75976 1 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.6839582745982573 0.6194430380553481 0.5356245361154941 1.0 0.748548182521791 2 P05026 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.3334429616228905 0.5792612046390768 0.5624129384662908 1.0 0.7683406739551267 21 P15291,Q10472,Q10471,Q9NYU2,Q16739,O60762,Q8NBJ5,P26572,Q8N4A0 9 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.6640298836046461 0.5588560009649377 0.5762599996367266 1.0 0.7773100203305943 3 Q9UGJ1 1 +GAR domain superfamily [IPR036534] 0.6656329292359782 0.5538626621726316 0.5796728398775026 1.0 0.7773100203305943 2 Q03001 1 +Chloramphenicol acetyltransferase-like domain superfamily [IPR023213] 0.4926021305150265 0.5368108541982309 0.5913982733420762 1.0 0.7773100203305943 5 P23786 1 +EB1, C-terminal domain superfamily [IPR036133] 0.6597124330420129 0.533200445309304 0.5938948333028762 1.0 0.7785769685622222 2 Q15691 1 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.6487046236943669 0.5076575606978838 0.6116935158608277 1.0 0.7952034501094355 3 Q9UEY8 1 +RmlC-like jelly roll fold [IPR014710] 0.376992668315 0.4161421647753777 0.677305977529767 1.0 0.8320953726363279 9 P38435 1 +Cyclic nucleotide-binding-like [IPR018490] 0.4594452681250583 0.4060279431941459 0.6847220689472757 1.0 0.8331468527550085 5 Q6P4Q7 1 +Galactose-binding-like domain superfamily [IPR008979] 0.3387423231974846 0.3960500178813176 0.6920681297071816 1.0 0.8380705837693642 13 Q8IW92,P08236,P16278,Q08431 4 +FF domain superfamily [IPR036517] 0.6094449256379582 0.3844069782949287 0.7006768291908796 1.0 0.8424706017253654 3 O75400 1 +SH3-like domain superfamily [IPR036028] 0.2805307227046703 0.3706928318327317 0.7108663299315745 1.0 0.8462458838102035 35 Q9Y371,P46108,Q96PC5,Q5JRA6,Q9UQB8,Q9UNF0,Q96RU3,Q14185,Q8N3R9,Q92783,Q07157,Q9UDY2,Q8N5V2,Q14155,Q13813,Q14168 16 +Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035] 0.4785270355049836 0.3549408016890407 0.7226339406541336 1.0 0.8538993367197488 4 Q9NP80 1 +14-3-3 domain superfamily [IPR036815] 0.416596104995761 0.3504330631815777 0.7260137167315803 1.0 0.8567130501733863 6 P63104,P61981,Q04917,P31946,P62258 5 +Oxysterol-binding protein superfamily [IPR037239] 0.4157185741287966 0.3469789720779783 0.728607116386206 1.0 0.8587759051605397 6 Q9H1P3,Q9BXB4,Q9BZF1,Q96SU4 4 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.4120304095329343 0.3325744157755925 0.7394555582816549 1.0 0.8625566558141922 6 Q9NZ08 1 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.4120304095329343 0.3325744157755925 0.7394555582816549 1.0 0.8625566558141922 6 Q9NZ08 1 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.3522099279319445 0.2810304417133087 0.7786870512162403 1.0 0.8939503322437289 8 P98164,Q15165 2 +Vps16, C-terminal domain superfamily [IPR038132] 0.5697772765717588 0.2602155494172899 0.7946975106057603 1.0 0.9069324525094492 2 Q9H9C1 1 +Chaperone J-domain superfamily [IPR036869] 0.2889023039855891 0.2328348767770189 0.8158896293382505 1.0 0.9259315701144308 20 Q96DA6,Q9UGP8,O60884,O75937,Q96KC8,Q9UBS4,Q96EY1,Q13217,Q9NVH1,Q8IXB1 10 +Moesin tail domain superfamily [IPR008954] 0.5528951992478712 0.2319593668539759 0.8165695736442224 1.0 0.9259315701144308 3 P35241 1 +H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664] 0.5334085142373974 0.1768788596528466 0.8596035443395575 1.0 0.95487155595664 2 Q9NY12 1 +High mobility group box domain superfamily [IPR036910] 0.3038845928670374 0.1764399760917302 0.859948300886147 1.0 0.95487155595664 12 O96028 1 +Ribosomal protein S7 domain superfamily [IPR036823] 0.5303073019453223 0.1705974500064399 0.8645403031323053 1.0 0.957876715357058 2 Q9Y2R9 1 +Cobalamin-binding domain superfamily [IPR036724] 0.5257964477022941 0.1616968603849712 0.8715445770554067 1.0 0.9594560873590016 2 Q99707 1 +NUDIX hydrolase-like domain superfamily [IPR015797] 0.3334841421796929 0.1441486872430364 0.8853830592941605 1.0 0.9672571916589968 7 Q9BW91,Q9BQG2 2 +HORMA domain superfamily [IPR036570] 0.5038060332675687 0.1223231435047659 0.9026431037643968 1.0 0.9726079895070218 2 Q13257 1 +KA1 domain/Ssp2, C-terminal [IPR028375] 0.488299971807168 0.0985385009086191 0.9215047014001398 1.0 0.9835061608673876 2 P54646 1 +Helix hairpin bin domain superfamily [IPR029012] 0.4851987595150937 0.0941693999627226 0.9249745920214228 1.0 0.9841063890980504 2 Q9H9H4 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.4826830332942347 0.0941106488025136 0.92502126140614 1.0 0.9841063890980504 3 Q9BYT8 1 +BRK domain superfamily [IPR037259] 0.4812517620524492 0.0887926505751003 0.9292466986123652 1.0 0.9875676211194176 2 P51532 1 +Fibronectin type III superfamily [IPR036116] 0.3126607333054748 0.0799183882785561 0.9363021648758648 1.0 0.9911495447712416 7 Q92859,P10586 2 +Isoprenoid synthase domain superfamily [IPR008949] 0.3738636432544485 0.0796454389776676 0.9365192549019604 1.0 0.9911495447712416 4 Q86YH6,P37268 2 +NTF2-like domain superfamily [IPR032710] 0.3063549103656078 0.062532582419038 0.95013871568468 1.0 1.0 7 O43615 1 +RuvBL1/2, DNA/RNA binding domain [IPR042487] 0.4465745700592136 0.05001253906127 0.9601123961010848 1.0 1.0 2 Q9Y230 1 +PDZ superfamily [IPR036034] 0.2396260673662038 0.0294002510430399 0.9765453725890254 1.0 1.0 26 P57105,O00560,Q5T2T1,Q96L92,Q07157,Q13425,Q9UDY2,Q8N3R9,Q14168 9 +ArfGAP domain superfamily [IPR038508] 0.4283699943598436 0.029087641901383 0.9767946919628958 1.0 1.0 3 Q8N6T3,Q8N6H7 2 +ARFGAP/RecO-like zinc finger [IPR037278] 0.4283699943598436 0.029087641901383 0.9767946919628958 1.0 1.0 3 Q8N6T3,Q8N6H7 2 +EYA domain superfamily [IPR038102] 0.4048491683112556 0.0209602969020949 0.9832773271941904 1.0 1.0 2 O95677 1 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.4003383140682336 0.0187697771408372 0.9850247639220392 1.0 1.0 2 O00443 1 +Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045] 0.3986467437270996 0.0179894778961282 0.9856472474767242 1.0 1.0 2 Q8TAG9 1 +Dynein heavy chain, domain 2, N-terminal [IPR042222] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain AAA lid domain superfamily [IPR042219] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, AAA1 domain, small subdomain [IPR043157] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, C-terminal domain, barrel region [IPR043160] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Dynein heavy chain, linker, subdomain 3 [IPR042228] 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044] 0.3987591652566277 0.0071498184421739 0.9942953188562792 1.0 1.0 3 Q6NUQ1,Q8TAG9 2 +CRIB domain superfamily [IPR036936] 0.3628418381731063 0.0059847893505776 0.9952248574833068 1.0 1.0 2 Q13177 1 +Thioredoxin-like superfamily [IPR036249] 0.2517614856638479 0.0058790576417532 0.9953092176970912 1.0 1.0 51 Q9H1E5,P07237,O75880,Q9P2K2,Q9H3N1,Q9H2J4,Q9H7Z7,O15217,Q96JJ7,Q9Y320,Q96CS3,Q96J42,O95881 13 +BAG domain superfamily [IPR036533] 0.3942470389170985 0.004515456002035 0.996397199614118 1.0 1.0 3 Q9UL15,O95429 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..455554f60a955ef08d248bbedf3e72d37ea41c99 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ASC domain superfamily [IPR037256]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deltex, C-terminal domain superfamily [IPR039399]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Focal adhesion kinase, targeting (FAT) domain superfamily [IPR036137]", "Folliculin, DENN domain, C-terminal superfamily [IPR044886]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MAP kinase activated protein kinase, C-terminal [IPR027442]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NFRKB winged helix-like domain superfamily [IPR038106]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phospholipase C-beta, C-terminal domain superfamily [IPR042531]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin kinase domain superfamily [IPR023465]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCAN domain superfamily [IPR038269]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOCS box-like domain superfamily [IPR036036]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Somatomedin B-like domain superfamily [IPR036024]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spindlin/spermiogenesis-specific domain superfamily [IPR042567]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBCC, N-terminal domain superfamily [IPR038397]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP5S", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATRX", "ATXN10", "AURKA", "B4GALT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHB", "BCKDK", "BCL2L12", "BCOR", "BCR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD2", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDKAL1", "CDX2", "CEBPZ", "CELF1", "CENPE", "CEP170", "CERS2", "CERS5", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ5", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC27", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCTD", "DCTN1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDHD2", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENND4C", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FOXRED2", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOPC", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGFL2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS14", "INTS4", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAM3", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD3", "KCTD5", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLHDC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED21", "MED25", "MEPCE", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL9", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOB4", "MOCOS", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEK9", "NELFE", "NENF", "NEO1", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NRBP1", "NRDC", "NRDE2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD6B", "OXNAD1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKAB1", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBF1", "SCAF11", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIL1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMS", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNJ2BP", "SYVN1", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL2", "TBL3", "TBPL1", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "TGS1", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFC3H1", "ZFPL1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF106", "ZNF24", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYG11B", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ACP6", "ADD3", "AGK", "ANKLE2", "AP1M1", "AP2S1", "AP3M1", "APP", "ARFGAP1", "ARFGAP2", "ARHGEF7", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP7A", "B4GALT1", "BAG4", "BAG5", "BAIAP2", "BCKDK", "BSDC1", "BSG", "CALU", "CD47", "CERS2", "CERS5", "CETN2", "CLCN3", "CLCN6", "CNNM4", "COLGALT1", "COPZ1", "COX15", "COX7A2", "CPD", "CPT2", "CRK", "CTDSPL2", "CTSA", "CYB5B", "CYB5D2", "CYP20A1", "DCUN1D5", "DERL1", "DERL2", "DNAJA2", "DNAJA3", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC19", "DNAJC3", "DNAJC8", "DOCK1", "DPM1", "DST", "DYNC2H1", "ECE1", "EFCAB14", "EMD", "ENDOD1", "ERAP1", "ERLIN2", "ETFDH", "EXOC6", "EYA4", "FADS1", "FAF2", "FCGRT", "FDFT1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FLOT1", "FNBP1", "FOXRED1", "FUCA2", "FUS", "GAA", "GALNT1", "GALNT2", "GALNT4", "GAR1", "GBA", "GGCX", "GLA", "GLB1", "GLB1L2", "GNS", "GOSR2", "GSTA4", "GUSB", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HSP90AA1", "HSP90AB1", "HSP90B1", "IGF2R", "KIAA0319L", "LDAH", "LETM1", "LMNB1", "LMNB2", "LPCAT1", "LRP1", "LRP2", "MAD2L1", "MAN1A2", "MAN2B1", "MAPRE1", "MFGE8", "MFSD3", "MGAT1", "MIA2", "MIA3", "MICU1", "MICU2", "MPP2", "MPP5", "MPP7", "MRPS7", "MTCH1", "MTCH2", "MTR", "NAGLU", "NAP1L4", "NEDD4", "NEO1", "NGEF", "NLN", "NNT", "NSD2", "NT5C2", "NT5C3B", "NUCB1", "NUCB2", "NUDT12", "NUDT9", "OCLN", "OS9", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PACSIN2", "PAK2", "PARL", "PCYOX1", "PCYOX1L", "PDCL3", "PDK1", "PDSS2", "PFDN2", "PFDN6", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PIGG", "PIK3C2A", "PLA2G15", "PLXNB2", "PNPLA8", "PON2", "PPT1", "PPT2", "PRCP", "PRKAA2", "PRPF40A", "PSME2", "PSME3", "PTGES2", "PTPRF", "RBM10", "RBM5", "RCN2", "RDX", "REPS1", "RINT1", "RUVBL2", "S100A13", "SCFD1", "SCO1", "SCPEP1", "SDCBP", "SDF4", "SEC63", "SEL1L", "SET", "SH3GLB1", "SLC25A10", "SLC25A12", "SLC25A15", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC33A1", "SLC4A7", "SMARCA4", "SNTB2", "SNX27", "SPNS1", "SPTAN1", "STAM", "STARD7", "STOM", "STOML2", "STX10", "STX12", "STX5", "STX6", "STX7", "SV2A", "SYNJ2BP", "TAF15", "TAP1", "TIGAR", "TIMM10B", "TIMM44", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TMED2", "TMPO", "TMX1", "TMX2", "TMX3", "TMX4", "TSPAN10", "TSPAN6", "TUBGCP4", "TXNDC12", "TXNDC15", "TXNDC16", "UGCG", "UGGT1", "UXT", "VAMP7", "VDAC1", "VDAC2", "VIPAS39", "VPS37B", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b2b1d3e31851c6905a093a9239a9bf9fdb4ccf5 --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/advanced/plot_0.png b/interpro_ptm/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..de602e97f21856198c0ffbb1bc4ac8d6c6b776bf --- /dev/null +++ b/interpro_ptm/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35d6ebc24702215dd95adac204d4207e77b528b2d436f733fba6ceaf6429e325 +size 169724 diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b2b1d3e31851c6905a093a9239a9bf9fdb4ccf5 --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/basic/plot_0.png b/interpro_ptm/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f3ff53fc1fc2a7cee6277fc5fe71870c7edc1d57 --- /dev/null +++ b/interpro_ptm/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:436a16002f8d387dbfb4e55ea30721ea3f68b94c90c7829786ca09fa4491f28b +size 141061 diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3a7c19146bb2188a42f1d71499a5a08dddd4cd88 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6aebd6667e8e5ae4d085fc6751b9714f78dd70a05545e6220e6c54e7331ac4e1 +size 79121 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5b2ce99d53ba0a1cd18840c2ccd5130d9f007e66 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +P-type ATPase, phosphorylation site [IPR018303] 5 8 2.231514973742304 0.0256470367803576 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0192115706028201 1.0 1.0 0.4172977923286156 0.0201372619620155 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..38f5b74a2214b0d3d4f9784ecc8615a3d0e4f9bc --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 5, + "title": "Average number of proteins per term", + "value": 3.0 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d00bada08cbb4149ca41d7f7579311b940bf8613 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9ab3926f1ce8a09c9c7f6a4e75d58f3e61924394 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7167406340345546 2.231514973742304 0.0256470367803576 0.1218240253729725 0.064117591950894 8 Q9HD20,P16615,P20020,P23634,P05023 5 +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.5611245371303992 0.6623273826173357 0.5077614315207377 0.971101307400322 0.5077614315207377 4 P98164 1 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ce9e099b26f2f624091b43a010bc311b6d93a91a --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Rapamycin-insensitive companion of mTOR, phosphorylation-site [IPR029259]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "EIF5A", "FASN", "LDLR", "LRP1", "LRP2", "RICTOR", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "LRP2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4ff6b929fe49c2394a95f27c8a5316cbb84b4f24 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4e1d4f3352fbca06b7175971c87ad5cd6eef5c6bb0ad40a41ce8e7c94a79068 +size 187009 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d65a0a8f7ab32d49f1f208eea20d6fe356dff1ef --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Spectrin repeat [IPR002017]", "2": "Spectrin/alpha-actinin [IPR018159]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e3ecd195387e875ab88e757db53856d88d909a6a --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8c88baee067ff7254407ef71a82a3d2dbd68124289d2c7ef0175b46f2f32ff08 +size 147912 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..df63b4eb4b52fccf762a306e38a1c1a684476ec2 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf425f006887feef59da5c70e8f80531f113313762f85385569f31d4ba0c0db2 +size 132756 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..8244d37084c1e1216f4257c9f60515284f308752 --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:128e2b0328e3a71e3bfddc5ae4573c09d485595f62bad9811e1f3801d41b48d8 +size 140094 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0404a10e393be76381845fc4d780dfb756ed26a6 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:970ea183aadd889409b56a57818965a92a81902ea8576aaab7dc425ad940fb8c +size 87625 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c3bdc9066b4fdbe98da3d32c57bb56d331a05a06 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 14 21 3.777538800238275 0.0001583858356473 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.0903515335443376e-08 0.1644315705571846 0.0513963234576887 2.9874917190946567e-05 1.2929972163241432e-08 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d0967dd26705ee021948dc78ffafb260d8c394fa --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 84, + "title": "Average number of proteins per term", + "value": 5.595238095238095 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e4514469b43221225a0445f71fdeabe3cec51874 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..30385372181151c1d71a3daa1ea6dff47a89add4 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7577332926540346 3.777538800238275 0.0001583858356473 0.0132173375228223 0.0133044101943743 21 Q6NUK1,Q9Y619,O75746,Q9BSK2,Q9HC21,Q9NZJ7,P12236,Q9H2D1,Q70HW3,Q9UBX3,Q9Y6C9,Q9BQT8,P05141,P12235 14 +Spectrin repeat [IPR002017] 0.6454145619766969 1.9292063776581208 0.0537052467472713 0.990312308506606 0.2050563966713998 10 Q8WXH0,O43707,Q03001,O15020,Q13813,Q01082,P46939,P12814 8 +HEAT repeat [IPR000357] 0.5681296193753669 1.4303243120178746 0.1526239601548478 0.9999990913448176 0.4006378954064755 8 Q8TEX9,P30153,P30154,Q6PJG6 4 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.605724789582991 0.845849870380087 0.3976365007234159 1.0 0.681662572668713 4 P98164,Q07954 2 +Spectrin/alpha-actinin [IPR018159] 0.417065168384526 0.8058465889878058 0.4203313111055444 1.0 0.7061566026573147 12 Q8WXH0,O43707,O15020,Q13813,Q01082,P12814 6 +LDLR class B repeat [IPR000033] 0.6113519633954624 0.3900989726082025 0.6964633625141556 1.0 0.8357560350169867 3 P98164 1 +HEAT, type 2 [IPR021133] 0.3325004674670167 0.3607471676755147 0.7182884609196216 1.0 0.8498060664401157 13 P30154 1 +Tetratricopeptide repeat 2 [IPR013105] 0.357384300464444 0.0917984540920564 0.926858172333197 1.0 1.0 5 Q02790,Q6N069 2 +Protein prenyltransferase, alpha subunit [IPR002088] 0.3752466873414137 0.0092642700649769 0.992608287682577 1.0 1.0 2 P49354 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0ede44484cec931c9f9f170a648478f933bbacae --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "KNL1 MELT repeat [IPR043651]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "Opioid growth factor receptor repeat [IPR006770]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "YD repeat [IPR006530]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACBD6", "ACTN1", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD13A", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASB6", "ASPH", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DTL", "DYNC1I2", "EDC4", "EED", "EHMT1", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HERC5", "HTT", "HUWE1", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGAV", "JUP", "KAT7", "KCTD3", "KDELC1", "KDELC2", "KDM2A", "KIAA1468", "KLC1", "KLHDC4", "KNL1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NAA16", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGFR", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF39", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABEPK", "RABGGTA", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RPTOR", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SIN3B", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STRN3", "STUB1", "SUGT1", "SYNE1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TENM3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC4", "TTC7B", "UACA", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "XAB2", "XIAP", "XPO1", "YTHDC2", "ZC3H7B", "ZFC3H1", "ZNF106", "ZYG11B"], "leading_proteins": ["ACTN1", "ACTN4", "BRAT1", "DST", "FKBP4", "FNTA", "IPO4", "LRP1", "LRP2", "MTCH1", "MTCH2", "NAA16", "PPP2R1A", "PPP2R1B", "SLC25A10", "SLC25A12", "SLC25A15", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SPTAN1", "SPTBN1", "SPTBN2", "SYNE2", "UTRN"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..821a1f179578f6298d8da5190e3fc010d30b52c1 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Mitochondrion organization", "2": "Endomembrane system organization", "3": "Ion transport", "4": "Ion transmembrane transport", "5": "Membrane organization", "6": "Cation transport", "7": "Sphingolipid metabolic process", "8": "Membrane lipid metabolic process", "9": "Organophosphate ester transport"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..75dae10478b1908b73baece77a2a593332a8eea9 --- /dev/null +++ b/msigdb_gobp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5987c50e2d94f3c1e1af0061f173253e58c887fa46a811c620c5598cc87b185 +size 219469 diff --git a/msigdb_gobp/advanced/plot_1.png b/msigdb_gobp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..17312d559280fdc4ffb18a5e8d3be9fa7beeac78 --- /dev/null +++ b/msigdb_gobp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be85cb28deec2289886ef0907eac7fdadc219921c8dada6659781b26857c1038 +size 221526 diff --git a/msigdb_gobp/advanced/plot_2.png b/msigdb_gobp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..613a9f62269e42ccb1e455ab1b85b550ed8bddc2 --- /dev/null +++ b/msigdb_gobp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b3c26156d9df632b35f70edfe7c4856e5be69d1d51a3941b96e6b0341ccb223 +size 224052 diff --git a/msigdb_gobp/advanced/plot_3.png b/msigdb_gobp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..ca827428f28132d6823b9c1dbd368a7846fcffb8 --- /dev/null +++ b/msigdb_gobp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:447c13f8b9826153fad7d4558a869c9e43957ae0bc7b06d4ff655447a4b7a9a1 +size 220765 diff --git a/msigdb_gobp/advanced/plot_4.png b/msigdb_gobp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..25c99fced95f0e7f15caac10009ef3e00cacef47 --- /dev/null +++ b/msigdb_gobp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e08619442eb1b83ee810154d4bebf291f812bc31d34bfbfda9d771e19726966 +size 221014 diff --git a/msigdb_gobp/advanced/plot_5.png b/msigdb_gobp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..7959f9d01a291db710a3e6ef37d1d24f36062ad6 --- /dev/null +++ b/msigdb_gobp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50de23c1022297a0d4d053eb739f4b5c52b42790650b68db1ce85b6f81c2b8f0 +size 223266 diff --git a/msigdb_gobp/advanced/plot_6.png b/msigdb_gobp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..1c423fe97d34e06b6eceeb057f8f3bbef3f40778 --- /dev/null +++ b/msigdb_gobp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6764494b62f52cd68d17417524140d077be71e5507bad6af8644d5212b2da83 +size 218575 diff --git a/msigdb_gobp/advanced/plot_7.png b/msigdb_gobp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..3873dc06f9c7182a54bad2ea0a942c65848a8f0d --- /dev/null +++ b/msigdb_gobp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88fa164722aa99276cc083e94035e8f2ea70c26e3d67a5271e8b9abe160760a5 +size 200894 diff --git a/msigdb_gobp/advanced/plot_8.png b/msigdb_gobp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..19ccb0828a7c9726fd336a94997f1f276b1c2200 --- /dev/null +++ b/msigdb_gobp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29922e1be289317da6d24e1ff82586dbb41f9170d867f28a5f344435be556cbe +size 203409 diff --git a/msigdb_gobp/advanced/plot_9.png b/msigdb_gobp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..a120c1985aeb962d8baf2df111249d100d24a95b --- /dev/null +++ b/msigdb_gobp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:196c57000464e8a966a09029b0ff3345ad2a65b28694c4cff3bb7b6218ffa7ed +size 207525 diff --git a/msigdb_gobp/basic/idx2term.json b/msigdb_gobp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..180ba5a4a22ad0d67bec1d7c40c99a4b1bf957aa --- /dev/null +++ b/msigdb_gobp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Mitochondrion organization", "2": "Endomembrane system organization", "3": "Ion transport", "4": "Ion transmembrane transport", "5": "Membrane organization", "6": "Cation transport", "7": "Sphingolipid metabolic process", "8": "Membrane lipid metabolic process", "9": "Organophosphate ester transport", "10": "Inner mitochondrial membrane organization", "11": "Chemical homeostasis", "12": "Membrane lipid biosynthetic process", "13": "Anion transmembrane transport", "14": "Endoplasmic reticulum organization", "15": "Ceramide metabolic process", "16": "Organic anion transport", "17": "Establishment of protein localization to organelle", "18": "Protein insertion into membrane", "19": "Mitochondrial membrane organization", "20": "Carboxylic acid transport", "21": "Localization within membrane", "22": "Lytic vacuole organization", "23": "Sphingolipid biosynthetic process", "24": "Carbohydrate derivative transport", "25": "Mitochondrial transmembrane transport", "26": "Organic acid transmembrane transport", "27": "Cation transmembrane transport", "28": "Mitochondrial respiratory chain complex assembly", "29": "Nucleotide transport", "30": "Inorganic ion transmembrane transport", "31": "Organic acid transport", "32": "Protein transmembrane transport", "33": "Anion transport", "34": "Nitrogen compound transport", "35": "Proton transmembrane transport", "36": "Establishment of protein localization to mitochondrial membrane", "37": "Process utilizing autophagic mechanism", "38": "Liposaccharide metabolic process", "39": "Purine nucleotide transport", "40": "Ceramide biosynthetic process", "41": "Mitochondrial transport", "42": "Sterol metabolic process", "43": "Protein exit from endoplasmic reticulum", "44": "Transition metal ion transport", "45": "Protein localization to endoplasmic reticulum", "46": "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "47": "Protein localization to mitochondrion", "48": "Protein targeting to mitochondrion", "49": "Vacuole organization"} \ No newline at end of file diff --git a/msigdb_gobp/basic/plot_0.png b/msigdb_gobp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8a9f6f9a749d0db129a1ce1c40b65f940967acd7 --- /dev/null +++ b/msigdb_gobp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3aab05070bc51224dd0d3cacb9e6343e5d8f3a72b6a11d092b0b58287df61edf +size 139857 diff --git a/msigdb_gobp/basic/plot_1.png b/msigdb_gobp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ba5d87d5b5b3bc1ad358779529b4b0e02e98c8c4 --- /dev/null +++ b/msigdb_gobp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:671e7ae370e262cf8191645f4750381c80ef29f9aac02751553c585dfa188a29 +size 150105 diff --git a/msigdb_gobp/basic/plot_10.png b/msigdb_gobp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..406f217e4e3ef63cdec8410ee6f745db168e787d --- /dev/null +++ b/msigdb_gobp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:327aec95140fc33ada9b12eb338b4bc022cc38c32e50061d9d8bbcc487679b92 +size 145982 diff --git a/msigdb_gobp/basic/plot_11.png b/msigdb_gobp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..aa54b14aab1d0ecd5e2cf796afb3228704dde0b2 --- /dev/null +++ b/msigdb_gobp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3fd6ad7e2ba58c7c83d8726a9d44360d8fd87a4d7c392af55d00c453f25b2da +size 149775 diff --git a/msigdb_gobp/basic/plot_12.png b/msigdb_gobp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..c02fb98a6e23e4d2d77e563c718a58ae95ec381a --- /dev/null +++ b/msigdb_gobp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b80dab19bc9bea59b51b5df25950443c3162b02da776514474e019f4beccd892 +size 146601 diff --git a/msigdb_gobp/basic/plot_13.png b/msigdb_gobp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..3209ef3c342bbc20bdd585b17a47e0bfe4fadf29 --- /dev/null +++ b/msigdb_gobp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e966d36f5b12961a49409d1c4f636783dec1c73d4991a72d05be196a5145f9ef +size 144693 diff --git a/msigdb_gobp/basic/plot_14.png b/msigdb_gobp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..70248e1c38ac34be2d9e9e036c412e4c242c004a --- /dev/null +++ b/msigdb_gobp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac6ecf4d59cd55a195d08ff536961c9a4c1adddf297fd1426c07b5551e87c389 +size 149240 diff --git a/msigdb_gobp/basic/plot_15.png b/msigdb_gobp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..727eec9d018c6533311f022676dc709b0e99e8bb --- /dev/null +++ b/msigdb_gobp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ad1934b234d3fdd9d0655a21018e5c9ac9d28bdf308839ea18f0d04f46755fe +size 146583 diff --git a/msigdb_gobp/basic/plot_16.png b/msigdb_gobp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..488483eff75eeacb260f1b571000299510e2d0d6 --- /dev/null +++ b/msigdb_gobp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aa7f17c51aa0ac13b3cb0f7886ee14afa9ed6e37bcb31c7aa8a999c6c726e7ac +size 142666 diff --git a/msigdb_gobp/basic/plot_17.png b/msigdb_gobp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..80e809a61466043391955d15ec514cb7eb1e17e4 --- /dev/null +++ b/msigdb_gobp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ea7ed3e82ecff3ed5cb8a66250d69cf543660e91eed0f7e16c27ffd41f39ed5a +size 153846 diff --git a/msigdb_gobp/basic/plot_18.png b/msigdb_gobp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..b811e33210a603d64369c8bd094c5e0bac6b034f --- /dev/null +++ b/msigdb_gobp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:19788b4b19160803abf7bdb3a73e093b6ea1eeaecceb39ea71aae471f1ed01ed +size 144759 diff --git a/msigdb_gobp/basic/plot_19.png b/msigdb_gobp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..6a2e8084bee8382e264aec1cec62403a10737266 --- /dev/null +++ b/msigdb_gobp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ecd4f32d035774fb84ff789f706cff23682b35f2fdcaee001de58d142ace017 +size 149103 diff --git a/msigdb_gobp/basic/plot_2.png b/msigdb_gobp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6fa2ff3fe5f1b65270a89e360294ef6d324cbfc7 --- /dev/null +++ b/msigdb_gobp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:11e13bebef046cf6ea1c67c52c16f5f1f2ad613353ba53efd125216f14feb85e +size 153055 diff --git a/msigdb_gobp/basic/plot_20.png b/msigdb_gobp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..2b67105450c4c44bf8e4e7461f612b6ccd2bcef7 --- /dev/null +++ b/msigdb_gobp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63ca6a8fad7a19c0fcd048b7ed265867e45044930ac0f655df1e18b0641b270b +size 145570 diff --git a/msigdb_gobp/basic/plot_21.png b/msigdb_gobp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..6c8001f5a591e1a27b78baece067b0809052805b --- /dev/null +++ b/msigdb_gobp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b3e3291f18586832f546da46a0a2f1cfcd22622b23daee1b0a41241f8309493 +size 148601 diff --git a/msigdb_gobp/basic/plot_22.png b/msigdb_gobp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..e077ee1a3caf07b58a36c0676e5f6b502cc1a0de --- /dev/null +++ b/msigdb_gobp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6b50d0a87efaa4b59cc1cfe30d6e1e23e8b16ee8f2f93b3610b21cf48d69e28 +size 144403 diff --git a/msigdb_gobp/basic/plot_23.png b/msigdb_gobp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..b65570f8b2464505e2a00c943796c81405e092ab --- /dev/null +++ b/msigdb_gobp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:853572b0ba83faab4b538c7985f2c86179633d723709178aff3d8d54eb2bd4d6 +size 147903 diff --git a/msigdb_gobp/basic/plot_24.png b/msigdb_gobp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..a6f6c129860e289555dfe13f039c09a24255c548 --- /dev/null +++ b/msigdb_gobp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:48df6a3c4ca3e497fd2cd58bfde1718d8c742dbe9f3a29230c311a76bd754fc3 +size 145120 diff --git a/msigdb_gobp/basic/plot_25.png b/msigdb_gobp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..3018fb9c416d3105334e6fcf5f577dde9628c048 --- /dev/null +++ b/msigdb_gobp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b223d771b79b3b28fa8c8464196f321bcf64187d196c3def358fd32f5653fee4 +size 149397 diff --git a/msigdb_gobp/basic/plot_26.png b/msigdb_gobp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..e3525ff7820d39493b004904237d4972e258c01e --- /dev/null +++ b/msigdb_gobp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:560d4197264b24446b5d146165342486546934a4f25a506cd9352bf068cbdd04 +size 148738 diff --git a/msigdb_gobp/basic/plot_27.png b/msigdb_gobp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..22977200e1e74e2e7d87d9cc545ed2d1182c91ba --- /dev/null +++ b/msigdb_gobp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eea3f78a2e1cb4f90bbb4e95e2476233c18a86eecbbde4c3d95b3dd2a0e71c2d +size 144387 diff --git a/msigdb_gobp/basic/plot_28.png b/msigdb_gobp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..fb3ae4b0feae1245b4f5c5d053f069864cb0b162 --- /dev/null +++ b/msigdb_gobp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:34164ef535a2a78e8b5a3dbb022b2bc6d7953d1bcbaced80823e5f1e7b595601 +size 149672 diff --git a/msigdb_gobp/basic/plot_29.png b/msigdb_gobp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..236fc016cc68136ec2be4e6867ac1d9451aa14f7 --- /dev/null +++ b/msigdb_gobp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:161572d205243094249e5cc67a4a70850edeb7d99ef7d4ff64d5c5df9711ce6f +size 142493 diff --git a/msigdb_gobp/basic/plot_3.png b/msigdb_gobp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..027a92b694b4570c64f2fcc5258fd772fddd2e65 --- /dev/null +++ b/msigdb_gobp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c384c815b01b1eccf8e8824e6fec52f1e0fd2fd1852873d91343344ff673706f +size 136708 diff --git a/msigdb_gobp/basic/plot_30.png b/msigdb_gobp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..8e701c7cf90bc823370a8ef82e2b89d6a8ee54d2 --- /dev/null +++ b/msigdb_gobp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f472b514c26b4abf0c5225cb183c0acad274ea66bd232a3e337c05abce737956 +size 147000 diff --git a/msigdb_gobp/basic/plot_31.png b/msigdb_gobp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..99c6cf67c3cabe9914db77d97a0cf83e03fa46df --- /dev/null +++ b/msigdb_gobp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:55a5765ad637514a50815874b92b34f272654ee9cbeee0b7a1da50f855dcb1ee +size 145858 diff --git a/msigdb_gobp/basic/plot_32.png b/msigdb_gobp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..c153cd1cd272b735b395fb0ecbb7f861a22f6f73 --- /dev/null +++ b/msigdb_gobp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2998416c819c0885b57f935ceaf314dcb487e56b9cca407cffbdff4594798f15 +size 146406 diff --git a/msigdb_gobp/basic/plot_33.png b/msigdb_gobp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..a4111d97c3457ae15c2453e0590355c966f11607 --- /dev/null +++ b/msigdb_gobp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f24ec8c2d06959a4c4debf0ff0430bc744dfc7a9b204a846d64ae482cf10f3ee +size 137157 diff --git a/msigdb_gobp/basic/plot_34.png b/msigdb_gobp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..4e4fa42b88ff252872478586ce80a8969097207a --- /dev/null +++ b/msigdb_gobp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:879c29faafa4077d40de919e2cdb2cd9f5e7910281803c801a40d4f25a30b191 +size 145979 diff --git a/msigdb_gobp/basic/plot_35.png b/msigdb_gobp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..a4de1efa35cc8feb85a10403cf20e1ff105cca07 --- /dev/null +++ b/msigdb_gobp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ddc54b594061bf928f8e6ad420bc9b28050f98e65d0df69847e22ad8eb00a72 +size 145717 diff --git a/msigdb_gobp/basic/plot_36.png b/msigdb_gobp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..aaa37999312a3c40b6b49fc20df526f4874da66a --- /dev/null +++ b/msigdb_gobp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2781fafbb5059e1ab44749fb4c63f12f3da6835fac0b88fee0c1c9ced1bab260 +size 147452 diff --git a/msigdb_gobp/basic/plot_37.png b/msigdb_gobp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..87aa009e2def6f6c2c0ac651aa536631e4ae1d57 --- /dev/null +++ b/msigdb_gobp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:723c72bc982254b9e2842972e7bc799225df643739620d210793af67c6c2d66d +size 152967 diff --git a/msigdb_gobp/basic/plot_38.png b/msigdb_gobp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..b32ac4a77ff1911f56385f32f71a4af0f5d4ad5f --- /dev/null +++ b/msigdb_gobp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2542c027007e2fa0901ff0ee958a8615f0b88f5c20ba0b314e8c496f079520e +size 144695 diff --git a/msigdb_gobp/basic/plot_39.png b/msigdb_gobp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..e1c1afda866e83080b8662bf302f0967c1eb429a --- /dev/null +++ b/msigdb_gobp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:edfacc594f6cffa8771253266c264f4db7ec57f2bd9d73adda877a1c47813ebe +size 141147 diff --git a/msigdb_gobp/basic/plot_4.png b/msigdb_gobp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..88084f2a5ccb92cf8570e7513346bc6912414576 --- /dev/null +++ b/msigdb_gobp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9cd24af26be62e6f65259f2dcc64675cd3491c721efb53680992368afcb38306 +size 144377 diff --git a/msigdb_gobp/basic/plot_40.png b/msigdb_gobp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..bb3059c47b28814cd927b85833af767effee3f8b --- /dev/null +++ b/msigdb_gobp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:44202dffab762dd40e791c5e65517d9c670dda21deb7ebed40ada5cba7db2324 +size 148241 diff --git a/msigdb_gobp/basic/plot_41.png b/msigdb_gobp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..850159ef1019c94300468e43df204a200ed5dcb9 --- /dev/null +++ b/msigdb_gobp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:65baf920f610ec658822df6e0688827dd93050015b087628507305edb5c31826 +size 141482 diff --git a/msigdb_gobp/basic/plot_42.png b/msigdb_gobp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..547ea6cb8435e7525d5a102994bebf801c6b31f5 --- /dev/null +++ b/msigdb_gobp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:891ca1c9d341ffa24679168d7a2ac659fdb31999332168089da412b0203007dd +size 143670 diff --git a/msigdb_gobp/basic/plot_43.png b/msigdb_gobp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..d51aac0aff788def8c09e05c7b77f6c9716ff42f --- /dev/null +++ b/msigdb_gobp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eaeb027263f1854ac9704bb9fcb2015146a52672c6659aed6b68a4623cab2885 +size 147879 diff --git a/msigdb_gobp/basic/plot_44.png b/msigdb_gobp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..36f3482086b82695d420ce6ef46c2f4d18ba6321 --- /dev/null +++ b/msigdb_gobp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:893291a9a39644e1cdaf8aba4d7bae5c2884288f9d985615f772c5ee9ba6b238 +size 141863 diff --git a/msigdb_gobp/basic/plot_45.png b/msigdb_gobp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..9ac020357050c31f38a119053fd7ebd841baed4d --- /dev/null +++ b/msigdb_gobp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:460fd8870cc9f31d92e3d16a50fa0cd5dadb2438d3ef54ac75a644a97e901e7c +size 146469 diff --git a/msigdb_gobp/basic/plot_46.png b/msigdb_gobp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..645db6266478897b3aeb4762619af35e04d591e4 --- /dev/null +++ b/msigdb_gobp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e7242b93a83df0240c874cb84b8ed9c4c99fb7796125c7eb00e7f7d740b8660 +size 152260 diff --git a/msigdb_gobp/basic/plot_47.png b/msigdb_gobp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..48557899f7f5995699efa6608a1d936bf45c9003 --- /dev/null +++ b/msigdb_gobp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d1266f943e4d7cbee1f36b710649cc0ad07cc3b99832eb2c80577c365d0125d +size 144547 diff --git a/msigdb_gobp/basic/plot_48.png b/msigdb_gobp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..a35313c422b7d491a353e93c4b1e586278219f3f --- /dev/null +++ b/msigdb_gobp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e0632c25043f506f838fd594d99f7f02f11d01bfb8184ed0c414ffa5b709bbc +size 145080 diff --git a/msigdb_gobp/basic/plot_49.png b/msigdb_gobp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..f93cc8749c73bc9bd116a5f7251df770adf581ac --- /dev/null +++ b/msigdb_gobp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:54be7d7ac5392d230bb87a0388705fadbc3011dab355cb79bc1ad6e791993215 +size 143255 diff --git a/msigdb_gobp/basic/plot_5.png b/msigdb_gobp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..d595ed9b6a19a75deb6230e5cce3395f489d2289 --- /dev/null +++ b/msigdb_gobp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d7e39e90c47f48d52e70f54b7362a47d9b54feae80ec599e9f8b64b113fd04f +size 149185 diff --git a/msigdb_gobp/basic/plot_6.png b/msigdb_gobp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..cd252314202add32e57cfe9b27bd7308648a06e1 --- /dev/null +++ b/msigdb_gobp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fa4c657de2b574f30ce90f7603d1dafb81620f28da4c25c13018ceddfb5e11c +size 146500 diff --git a/msigdb_gobp/basic/plot_7.png b/msigdb_gobp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..3495592a1b3160d4858b997b758b847d0df3b8fb --- /dev/null +++ b/msigdb_gobp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2409d88b783623c761c3c32edb30110d803a29d9d3b63d3579e85f26fde07790 +size 149543 diff --git a/msigdb_gobp/basic/plot_8.png b/msigdb_gobp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..df32cf4bfb1289a47802e3ad4cb55aa3ec6125cb --- /dev/null +++ b/msigdb_gobp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6482fa997b3efa7c985a3c2d6ceafd1367c1888c90dad7c421db1a4a729a969c +size 148262 diff --git a/msigdb_gobp/basic/plot_9.png b/msigdb_gobp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..eab7937aea1ebf1d06014b9376e24a5b5e79e14b --- /dev/null +++ b/msigdb_gobp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f312024a6c430b60d2be8bbd38479e2fc18ce0a510c9c6ba9c57479ca3d7523b +size 146245 diff --git a/msigdb_gobp/consensus.joblib b/msigdb_gobp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..325b7a93f2bad43ab219886f06d2c2b37f73bc22 --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89d9a4ee58b5119e8a3627e58f10d7d292c9185f730c2dae27789f98820d1355 +size 505069 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4517f80b5c4c46b3e2ba434afddd5361ea681cf1 --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,238 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transmembrane transport 99 245 6.505996789516746 7.717987434600111e-11 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 3.896334305172117e-17 0.0001606735243173 1.4457377806045573e-07 4.474904470691338e-13 2.82843831301584e-17 +Mitochondrion organization 89 211 6.162477854113121 7.161534925632761e-10 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 2.177214661721297e-17 4.062710340017348e-06 7.088869679689821e-07 1.2026105314719203e-09 1.1509243156441836e-17 +Endomembrane system organization 86 198 6.109533892148429 9.992253536608982e-10 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 1.3546772152706543e-06 0.8445989557484985 0.3151963186303143 0.0260617116291466 2.938478979733076e-07 +Ion transport 104 230 6.06226858572246 1.342148386654309e-09 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 2.320249725663649e-11 0.0275105950473259 2.8064449418348413e-05 5.458895096583705e-08 5.924539995409215e-12 +Ion transmembrane transport 85 176 5.791395132318482 6.980413795932994e-09 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 1.8390826273397864e-12 0.0051922940908961 6.49370644714716e-06 2.965323017086803e-10 1.0412628122199377e-12 +Membrane organization 114 254 5.669818065097187 1.4294923690683751e-08 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 3.865801654568525e-13 0.457339210262795 0.3992570105371746 1.1612117065482576e-05 7.547735171968882e-14 +Cation transport 74 171 4.905424140064735 9.322566676650868e-07 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 1.781469107592254e-07 0.0829547176038009 0.0009019434466977 2.619702344182993e-05 4.485664286603521e-08 +Sphingolipid metabolic process 23 32 4.788881812759471 1.677132148270033e-06 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 5.6549336433376227e-11 0.0097273770857752 0.0126614085231583 1.580618245878458e-05 7.524357422977594e-11 +Membrane lipid metabolic process 27 43 4.6671077065006 3.054692222059785e-06 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 3.4047851723515575e-10 0.0187223954820901 0.028278569718715 0.0001527751802754 4.590189558502003e-10 +Organophosphate ester transport 19 35 4.249828621112497 2.139341344142842e-05 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 8.036215737416288e-07 0.3121781622201707 0.5351022899588459 1.926020230279072e-05 9.705083787751065e-07 +Inner mitochondrial membrane organization 19 25 4.242408649603828 2.21133562348097e-05 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 1.8678720998952881e-13 0.1604648724397155 0.3009165941166509 2.226230744371199e-06 2.3558034057000873e-13 +Chemical homeostasis 87 200 4.218795436804168 2.456109847570609e-05 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 1.233434635300356e-05 0.1202947186762103 0.1674308857789419 0.016514891501609 8.598694382579696e-06 +Membrane lipid biosynthetic process 17 29 4.164022713362213 3.126889881510664e-05 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 6.733449319743734e-06 0.3219228357858488 0.5484830827387088 0.0485304500002844 7.994337080352117e-06 +Anion transmembrane transport 36 48 4.156807078642431 3.227262916949414e-05 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 5.651359713709531e-06 0.4122276163296383 0.0226460809255619 8.188374825428545e-05 1.6621397007675213e-06 +Endoplasmic reticulum organization 26 47 4.092832107387505 4.2613627329712855e-05 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 1.2535039733779195e-05 0.3022964060814402 0.1656331484196294 8.595459012009641e-05 2.983488332755011e-06 +Ceramide metabolic process 16 22 4.07917431886848 4.519593831631141e-05 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 5.7438364098684764e-09 0.0293895252151177 0.1039407380726692 0.000423196822916 7.0390588785564245e-09 +Organic anion transport 30 51 4.045840652130757 5.213568961059956e-05 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 1.6694713806506185e-05 0.4955746593898518 0.1608702453512187 0.0007395073544363 2.0511925354909628e-05 +Establishment of protein localization to organelle 59 199 4.039701500380365 5.351927137176027e-05 40.4247572815534 180.123786407767 0.6176411706537287 0.628535284461401 14.116769229706104 14.40373863390995 1.0281809729691214 0.3983757503188239 1.909166606439212e-08 0.0062635869187616 0.0022114565007734 5.412427097934532e-05 2.8962053340753148e-08 +Protein insertion into membrane 18 32 3.9574192667764407 7.576388181451676e-05 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 9.299351917813194e-10 0.0238997911322505 0.08610744549237 2.7324998355580223e-08 1.1442219875090924e-09 +Mitochondrial membrane organization 29 52 3.913452087005118 9.098596056489328e-05 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 1.801584751314145e-12 0.0748672511654648 0.2355439310831054 4.88351502042282e-07 2.4692422526057762e-12 +Carboxylic acid transport 25 37 3.912545361661947 9.13283759216288e-05 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0117324235017863 0.3922727602504912 0.0801526286479979 0.0137128382989162 0.0129452724374584 +Localization within membrane 76 212 3.87514503099924 0.000106561213595 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 5.479843895157955e-06 0.3976090918073597 0.1809163962518047 0.00026524502022 3.529174382396464e-06 +Lytic vacuole organization 21 29 3.8004228786909366 0.0001444493698734 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 2.204912663428549e-05 0.002776216406037 0.0002661164710619 1.2492792585708468e-05 2.538972545725035e-05 +Sphingolipid biosynthetic process 13 20 3.797073189664278 0.0001464145706282 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 3.227311732020842e-06 0.2436179272361805 0.4353012614103685 0.0138556470380734 3.774726798150127e-06 +Carbohydrate derivative transport 14 21 3.795604695512067 0.000147284022705 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 1.6486603488182724e-08 1.0 0.3593428278464597 0.0001074284133796 1.97441963311593e-08 +Mitochondrial transmembrane transport 27 55 3.7820614440481815 0.0001555349562558 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 7.342862110976441e-13 4.620057885845172e-05 1.6342529313586228e-05 1.1325122383507624e-07 9.984270486523811e-13 +Organic acid transmembrane transport 23 35 3.7361106949048426 0.0001868884235709 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0047317790236896 0.3154415256826839 0.1793408912067547 0.0006818386753638 0.0052250568684152 +Cation transmembrane transport 54 134 3.7167896449820224 0.0002017702994754 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 3.021363068812741e-09 0.0304263611237756 0.0008935089252406 1.2191438481898363e-06 1.572365229863144e-09 +Mitochondrial respiratory chain complex assembly 24 41 3.713298208372838 0.0002045755925805 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 5.695915996062012e-06 0.0089029299634258 0.0002332117630992 1.8108119815621985e-06 6.824407224381136e-06 +Nucleotide transport 12 17 3.5527309915212 0.0003812541271532 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 1.1086412222983005e-08 0.1155957163384056 0.2223047329091382 1.995989947939695e-06 1.2856393626457652e-08 +Inorganic ion transmembrane transport 51 128 3.537704233220071 0.0004036219020948 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 5.227000517645532e-09 0.021688978598281 2.217138360697473e-05 2.179561250656097e-07 2.590356805290882e-09 +Organic acid transport 31 50 3.4563075744402547 0.0005476300522431 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0315964594688928 0.4783938870567416 0.3803883597337516 0.0182037584987757 0.0346910214551516 +Protein transmembrane transport 10 27 3.432469063456782 0.0005981121147651 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 3.365510981724816e-05 0.0001068921937335 0.0001474440444245 0.0002678672315905 3.835317077580539e-05 +Anion transport 46 79 3.4107332749074435 0.0006478843623856 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 2.2573666699234145e-08 0.2424540817316537 0.012510098203701 2.757011435594295e-05 8.233039429643547e-09 +Nitrogen compound transport 227 648 3.4038576059867864 0.0006644137960813 134.15533980582524 569.4538834951456 0.9072063241864304 0.6401677607980054 37.1767641393764 58.81145048559368 1.470232145086419 0.4303798393104362 4.1524242779607115e-13 0.1102795128273353 0.0220644843436969 2.7644079801071243e-08 9.973419689398593e-14 +Proton transmembrane transport 24 48 3.288873153377157 0.0010058934624905 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 8.785392160223536e-06 0.0097273770857752 0.0002783591093982 2.5701466073143648e-06 2.358117139783515e-06 +Establishment of protein localization to mitochondrial membrane 12 19 3.265638934850177 0.0010921741283949 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 1.790635184575399e-08 0.0070670490819082 0.0274603336438859 2.6393235185604498e-06 2.075161383728372e-08 +Process utilizing autophagic mechanism 54 184 3.245924896160819 0.0011706971964848 37.22330097087379 158.8252427184466 0.4533218180510577 0.6759877406594806 11.85403297791327 20.589929287102564 0.8897283418769861 0.36588075882003 0.0005986843543008 0.3430476491220843 0.0607797714808847 0.0686419159945174 0.0003968383751509 +Liposaccharide metabolic process 11 20 3.2417987358703626 0.0011877787340142 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0003839504721476 0.2400196775334175 0.4297892617739207 0.0515621560092188 0.0004297622117065 +Purine nucleotide transport 9 14 3.2111619426285074 0.0013219941233888 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 1.9982918453667788e-06 1.0 1.0 9.22092773458021e-05 2.2237850571674797e-06 +Ceramide biosynthetic process 9 14 3.1988491257453555 0.0013797735633043 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 2.879026660008784e-05 0.1524760813950871 0.2872333566147377 0.0097601039903573 3.22142282967417e-05 +Mitochondrial transport 40 93 3.1830515624148727 0.0014573165975602 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 5.988148145770734e-13 1.2610802803762405e-05 3.3947960014797515e-05 1.318890738327389e-07 8.984444465246599e-13 +Sterol metabolic process 16 40 3.1677556092241868 0.0015362059920429 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 2.24580912781759e-06 0.3315322885250054 0.1967082241040804 0.0010205325993841 2.701437551586633e-06 +Protein exit from endoplasmic reticulum 14 27 3.1655931414319056 0.0015476710325756 7.002427184466019 21.233009708737864 0.6943602976218084 0.4745028866201709 3.210645812910548 2.182026685495945 1.0430444956616387 0.3507892727806736 0.0001632705518591 1.0 0.3404254693467198 0.0036383017284534 0.0001817739981452 +Transition metal ion transport 13 18 3.1571948424407483 0.0015929486836565 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.0067984937592421 0.2436179272361805 0.1100932826860655 0.0029289523616429 0.0073872398636599 +Protein localization to endoplasmic reticulum 16 38 3.153585314650297 0.0016127807962562 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0003317016257743 0.236404668572991 0.1039407380726692 0.000423196822916 0.0003715114570429 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 18 30 3.10273911468681 0.0019173858313432 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.0003326111401273 0.1993158438338612 0.0102837000876808 0.0265672828357611 0.0003693854345286 +Protein localization to mitochondrion 38 66 3.099993586767574 0.001935248328593 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 6.184518516059104e-09 0.0001448081705944 0.0005873272870129 5.861217240468368e-05 1.461908661695546e-09 +Protein targeting to mitochondrion 30 54 3.055963931617504 0.0022433824096268 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 4.147052007643123e-09 5.459959051029623e-05 0.0001940435749139 4.9861626098174725e-05 5.290606006816307e-09 +Vacuole organization 25 62 2.999632687286679 0.0027030536061931 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0012029985105951 0.0362209672326423 0.016676938082001 0.0130564574399452 0.0014032813321253 +Membrane lipid catabolic process 6 12 2.986536660441089 0.0028215700544933 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 2.511668512538341e-05 0.0001055314719321 0.0008717411361388 9.22092773458021e-05 2.7537597807274675e-05 +Cellular monovalent inorganic cation homeostasis 19 30 2.979662175207276 0.0028856643378882 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.0001304358112227 0.0029102285656399 0.0207328276809773 0.0034676048515423 3.0236033691112305e-05 +Tetrapyrrole metabolic process 11 22 2.965725626871329 0.0030196975470613 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.004578910583524 0.0181053013145446 0.0085749794431607 0.0006205149914719 0.0049481295197396 +Cytochrome complex assembly 11 13 2.95712770534325 0.0031051948132607 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.000158928930674 0.0110614955842043 0.0420348553288257 0.000144725329193 0.0001753252601336 +Retrograde transport endosome to golgi 23 37 2.9421231307190543 0.0032597028688774 8.844660194174757 34.00485436893204 0.6408100896550543 0.5235396612667444 4.365036019054001 3.8497226893137166 0.9745365654790862 0.3516062635557995 0.0449791504351954 1.0 1.0 0.1418336443700749 0.0482032035846316 +Protein insertion into mitochondrial inner membrane 6 8 2.9340927912309644 0.0033452418373305 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 3.5921643232053493e-07 0.0550816697898294 0.1094892401774078 0.000142755965642 3.957975029002194e-07 +Mitochondrial fusion 14 18 2.9238630564427366 0.003457168044312 5.730582524271845 14.140776699029129 0.9082040747396848 0.3521825448687026 2.97444400458197 2.016819417247653 1.0465735301082626 0.3054031781597867 0.0003471406336639 1.0 1.0 0.1552222190730896 0.000378511976274 +Establishment of protein localization 200 589 2.875952534068272 0.0040281028011748 118.26941747572816 516.7257281553398 0.6520395559374618 0.679532677582667 31.472560658738065 53.21298128179791 1.2523101724416292 0.4083128036600569 1.2740181039073292e-10 0.1255890381171911 0.0272611310885358 2.626015812311603e-06 2.9728535029883436e-11 +Monovalent inorganic cation homeostasis 19 34 2.8402670404578765 0.0045075782726498 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0006606002580902 0.0048349140039534 0.033011066423499 0.0083652800039346 0.0001875770683042 +Vascular transport 10 15 2.835349816514898 0.0045775531880039 4.774271844660194 13.094660194174756 0.7274519419599351 0.3186647470404632 2.3913310677559982 2.1617303908189505 1.2183781465172474 0.2807075669512824 0.4325395475422806 1.0 1.0 0.7074631838133625 0.4417527010218077 +Intracellular protein transport 120 365 2.8345864971686563 0.0045885034466546 72.23543689320388 320.84466019417476 0.4871189760263694 0.7214714639205947 20.45645165050656 29.914524602040487 1.0524664106682724 0.3751399671828122 8.67840745314168e-10 0.040111026294826 0.00572888099978 3.2336035473742337e-06 6.514157294493488e-10 +Nucleotide transmembrane transport 7 11 2.821832087100148 0.0047750171221516 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 6.260528599689891e-05 0.0727733471903131 0.1432798584585485 0.0004862334359502 6.779426412213311e-05 +Organelle fusion 28 57 2.819333315379072 0.0048123517646241 14.74514563106796 45.383495145631066 0.6448767361523368 0.5292766623385164 6.293825046556003 6.576179389035289 1.1045479661060835 0.3741954647136961 0.0004149252018717 1.0 1.0 0.1505102744264545 0.0004818613288652 +Sulfur compound transport 5 12 2.8192995371354104 0.0048128582565019 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0008045081858876 1.0 0.2732850813359189 0.0001216265378748 0.0008750939624126 +Calcium ion import 8 16 2.8180984890720047 0.0048308988938245 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.0016424600727882 1.0 0.048990890514732 0.2256009180273313 0.0017822844690718 +Regulation of ph 13 25 2.806991405977177 0.00500065757872 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0001506806965379 0.0018407641855875 0.0135419734012732 0.0082403851981354 3.176403402652151e-05 +Regulation of cellular ph 13 25 2.806991405977177 0.00500065757872 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 8.907390723787997e-05 0.001549818040453 0.0115248505447769 0.006410021202963 1.7491284227584308e-05 +Protein targeting 55 130 2.806082277847345 0.0050147885707674 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 8.100067120723551e-10 0.0001566733401048 0.0001428671553367 7.227554503110613e-07 3.240795817395088e-10 +Nadh dehydrogenase complex assembly 15 28 2.7944185229008816 0.0051993140807231 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 0.001435349653862 0.236404668572991 0.0021465314893355 0.000423196822916 0.001584251501391 +Glycosphingolipid metabolic process 7 10 2.7768582212022044 0.0054887115228583 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.000126786672537 0.1444128696349771 0.2732850813359189 0.007920049564759 0.0001399534495659 +Amino acid transport 17 20 2.768643113756444 0.0056290257562816 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.4235591888336107 1.0 1.0 0.2338841850044661 0.434304903746751 +Vitamin transport 7 9 2.7543361753897377 0.0058811324854224 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0007580426681942 0.1071891284628969 0.2070995190727305 0.0024379570615939 0.0008169542553505 +Cristae formation 8 10 2.747893844956347 0.0059979424907921 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 1.4308226186777996e-06 1.0 1.0 0.0439142352380576 1.5745699404944486e-06 +Golgi vesicle transport 47 149 2.7344547264115504 0.006248368739897 32.30825242718446 130.0995145631068 0.5186556770214802 0.6391424830765352 11.558195085956042 14.851278907933963 1.0581936514451007 0.3745819971007444 8.707802637310292e-06 0.7155846398970147 0.2465206288516762 0.0116878222785546 1.1498838774692085e-05 +Protein transmembrane import into intracellular organelle 5 14 2.725888777111882 0.0064128603754001 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0026192487907078 0.0086801325315587 0.0028960612595367 0.0352396407582777 0.0028128505043211 +Porphyrin containing compound metabolic process 10 19 2.687486253625376 0.0071992065456929 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0011654785980253 0.0116969452261847 0.0045096021611559 0.0001711644149485 0.0012662122150735 +Inorganic anion transport 20 33 2.684014011698967 0.007274405748781 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 1.9855310763674043e-05 0.2786952299090933 0.0043038530101662 0.0013505003452077 4.530035964786033e-06 +Dicarboxylic acid transport 10 17 2.683084842596801 0.0072946481779354 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.1405882590135279 0.1801156574188796 0.0614247268920475 0.0808776862517318 0.1458719137718038 +Protein import into mitochondrial matrix 4 10 2.679613485328433 0.0073707213772544 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0005000280862091 0.0021914548918381 0.0003602808960722 0.0051503840765812 0.0005338561483377 +Endoplasmic reticulum to golgi vesicle mediated transport 27 73 2.6758434344406816 0.007454145810203 17.32766990291262 65.39077669902913 0.808881464821498 0.4942452999677598 7.539018980743236 6.620812461410292 1.284359804176963 0.3933269611423161 3.164601280831886e-05 0.4205819691215787 0.0246695053344801 0.0067562470764985 3.788616181424059e-05 +Aminoglycan metabolic process 8 18 2.6745356629115844 0.0074832816600727 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0026190390449421 1.0 1.0 0.0037630129831157 0.0028819396603958 +Glycoprotein biosynthetic process 26 63 2.664072241350891 0.0077200981619693 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.0044559748826556 0.5954641326339 0.275702193658781 0.0172419469934396 0.0051580809413311 +Glycolipid biosynthetic process 7 12 2.646636367155373 0.0081296719795427 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 0.0274491625860484 1.0 1.0 0.5870305126491255 0.0289613396123399 +Neuromuscular process 6 28 2.635001662663932 0.008413687101711 6.682038834951456 25.487864077669904 0.5107907507501308 0.3958015985368521 2.5973040014911133 3.0533044809467955 1.2106508695866462 0.3144907539964949 0.0131702034083795 0.2683427616475903 0.0036673828223822 0.0216033331890521 0.0142520132559401 +Metal ion transport 49 111 2.633038806154821 0.0084624677848328 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.0013168510842208 0.4913390105790043 0.0499768395118841 0.0221596235254605 0.0008098062794879 +Regulation of lysosomal lumen ph 6 8 2.615688087771581 0.0089047861615321 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0005000280862091 4.282287459858128e-05 0.0003602808960722 0.000371706641515 0.0005338561483377 +Cellular homeostasis 70 157 2.6034592248390025 0.0092288244766332 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.0005676236894756 0.1369706360393974 0.2212619291054315 0.0281722634676529 0.0003698743846522 +Intracellular protein transmembrane transport 6 23 2.590090474292692 0.009595071055543 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0052037962080083 0.018891152845815 0.0091243340822671 0.0230341265569123 0.0056200963406339 +Establishment of protein localization to membrane 43 100 2.5787326740406984 0.009916349319609 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 1.4848797751727678e-06 0.0708539020687588 0.1330886303833328 2.163056328212412e-06 5.961004585904112e-07 +Sodium ion transport 14 25 2.5703907873685945 0.010158385108528 7.286407766990291 24.194174757281555 0.366064924510469 0.599746317765829 3.595508215659048 3.4684661348618055 0.8333080580344709 0.3307550501478689 0.0892770590720244 0.3656394840654732 0.2355439310831054 0.0833708244117331 0.0949960943179792 +Mitochondrial calcium ion homeostasis 7 13 2.5637454923653755 0.0103549443521577 4.62621359223301 10.509708737864075 0.2790428491871666 0.3774917598770124 2.1634860921400008 1.7383182679254283 1.294226020505384 0.3175561312397286 0.0003455086863903 1.0 1.0 1.0 0.0003730251283681 +Organelle membrane fusion 17 37 2.548829471636901 0.0108085137293028 9.026699029126211 29.49271844660194 0.2503440438263548 0.5991935201964022 4.297974887399588 5.110663265938685 0.9179616425810708 0.3357137012753883 0.0202391625142957 1.0 1.0 0.339549447449659 0.0219681008445407 +Golgi organization 29 68 2.542452097938156 0.0110077688619876 16.643203883495147 56.43689320388349 0.631232933893225 0.5683910993217528 6.594450257690171 8.413373430660274 1.0599635722797485 0.3790700076783576 0.0008461127029585 1.0 0.335158199257754 0.5818026208924209 0.0009775903507347 +Amino acid transmembrane transport 14 16 2.53812335748966 0.011144869319581 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.1872542329078324 1.0 1.0 0.1048323445251165 0.193832289989472 +Endoplasmic reticulum tubular network organization 6 12 2.5359285469039 0.0112149614430079 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 0.0009513571658216 0.0771453392642774 0.1515272625734178 0.0074273483269255 0.0010145405611514 +Homologous chromosome segregation 6 12 2.5347662212683733 0.0112522390914358 2.9441747572815533 9.983009708737864 0.8658101820521615 0.3886675393312038 1.6544409340956687 1.448870557748215 0.8756753907408087 0.3062582021532934 0.160353317011437 1.0 1.0 0.5094216597603356 0.1652047572335966 +Sodium ion transmembrane transport 13 21 2.534408296778756 0.0112637404415625 6.230582524271845 19.861650485436893 0.3704792335969762 0.5741696766418313 3.3118992073574036 3.0326356242212613 0.8979196459015502 0.333569210239074 0.0214238557943388 0.2889042268874887 0.152127800544383 0.0301335348401812 0.0231032125645871 +Regulation of membrane lipid distribution 7 10 2.528519159159948 0.0114544834489973 2.2475728155339807 5.5 0.9490281853542848 0.2470521989607894 1.5110816970578842 2.070950253254846 1.235309366119274 0.2447223644308076 0.0014751485015756 1.0 0.2297987482657219 0.0267619345648551 0.0015869747860804 +Antigen processing and presentation 12 26 2.513704753199583 0.0119470404727635 6.201456310679611 22.17718446601942 0.8231471183465873 0.4220086818460768 2.970845032857872 3.056135613532617 0.9682333159777928 0.3245513416930483 0.0543699534322455 1.0 1.0 0.4035011436345253 0.0575078377952935 +Glycoprotein metabolic process 36 72 2.5130058653227385 0.0119707344673853 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.0028044170956631 0.6598712392014866 0.3705363311771966 0.0216689429972678 0.0033144537056698 +Lipid metabolic process 116 308 2.5085573621314565 0.0121225283889747 70.49514563106796 273.7014563106796 0.4234492243219149 0.5257500979287635 24.98470358696109 28.74867152381156 1.6795947056521872 0.4126649977131845 9.641646663012606e-11 0.306402955621857 0.071075020063763 0.000283983985194 1.956610021430847e-10 +Ceramide catabolic process 4 7 2.5051816400549067 0.0122388522652798 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 0.0001486934237484 0.0013899505248691 0.0056684159955205 0.00262770885776 0.0001590313802548 +Plasma membrane organization 17 31 2.504071178286482 0.0122773332189463 7.099514563106796 28.24514563106796 0.6737258386983643 0.4958528160030953 3.5234718862626195 4.368421626063976 0.8695791931528731 0.3271220115282837 0.1921843066681736 1.0 0.5440657264544094 0.3128952059925546 0.2007835125015833 +Divalent inorganic cation homeostasis 23 60 2.5032808820189447 0.0123047846925534 15.361650485436892 54.019417475728154 0.5485088157809707 0.5170537035394376 6.04857242197355 6.215359275440269 1.1779017300469032 0.3778837346959196 0.0004818299341659 0.5816210605726648 0.528007824876168 0.2835849253067675 0.0005769704282847 +Ion homeostasis 58 124 2.480502164920524 0.013119746708017 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 3.5824527939644785e-06 0.0193432518921315 0.0404982889750165 0.0151404330672233 1.901015263500258e-06 +Secondary alcohol metabolic process 15 43 2.47972337643931 0.0131484344115562 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 3.09359698370832e-06 0.3378643758427397 0.2037147080402499 0.0011888751694869 3.716307933629515e-06 +Cellular lipid metabolic process 88 232 2.476742463260104 0.0132587534278973 55.06310679611651 205.83495145631068 0.2402431693065998 0.4937242414097398 20.280338607556292 23.717838556123585 1.6370289909336062 0.4061780961812439 2.210900831347729e-08 0.3045879820690314 0.0581448277155018 0.0011424314729494 3.735018802314397e-08 +Respiratory chain complex iv assembly 7 8 2.4742391209407457 0.0133520296014975 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 0.0059488175873696 0.1114021565620111 0.2147385524083838 0.0217985290060267 0.0063149437065281 +Diol biosynthetic process 4 9 2.472305069939807 0.0134244902809395 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0026425445039808 0.0016377422378922 0.0066572828402184 0.003355333516566 0.0027834726260547 +Diol metabolic process 4 9 2.472305069939807 0.0134244902809395 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0059987647490075 0.0024970154667983 0.0100519320580488 0.0062267265321947 0.00630824692371 +Regulation of dna templated transcription in response to stress 3 15 2.466212494843678 0.0136550300024429 2.8470873786407767 11.885922330097088 0.1387380176828835 0.4895467516437726 1.976418321285878 2.194232482701444 1.0022724956514792 0.2960877477393434 0.0920062303064251 0.0123481232007499 0.0466281418945222 0.0107757845080475 0.0957448321565225 +Homologous chromosome pairing at meiosis 5 9 2.463920972512335 0.0137426408137024 2.4975728155339807 8.245145631067961 0.965829654578573 0.3348869860078453 1.4047402178514554 0.97323438747629 0.9242483632276672 0.2995534430572119 0.0681744237474234 1.0 1.0 0.3879443652654283 0.0705348016344186 +Protein catabolic process in the vacuole 6 9 2.4627265871762005 0.0137885017592518 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.0021155878345267 0.0901405579438761 0.0155240337321844 0.0011993766429203 0.002252196025852 +Lysosomal protein catabolic process 6 9 2.4627265871762005 0.0137885017592518 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.0012658498659003 0.0814971443263516 0.0126574737404708 0.0007869115437374 0.0013491401517078 +Vesicle mediated transport 124 412 2.461752265953059 0.0138260129158456 80.64805825242719 354.7718446601942 0.3002670711784583 0.7468304035232791 23.646053491950397 43.46537941024834 1.061791523718338 0.3560152131667141 0.0117973335544427 0.338498612367634 0.3781321450030376 0.099412966208792 0.0032748912291471 +Vitamin transmembrane transport 5 7 2.460737714412266 0.0138651686694819 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0005000280862091 0.0683810764565047 0.1349531130589082 0.0051503840765812 0.0005338561483377 +Lipoprotein metabolic process 9 26 2.4600637248065187 0.0138912348206241 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.2226051880804218 0.0605318649589048 0.1967082241040804 0.339549447449659 0.2321175547305154 +Endoplasmic reticulum membrane organization 6 9 2.460044240973954 0.0138919889893742 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.0026425445039808 1.0 0.1180585699575878 0.0382400085743442 0.0027834726260547 +Positive regulation of macroautophagy 7 22 2.453806131664708 0.0141353165564181 5.058252427184466 20.34223300970874 0.7197293510270528 0.4154159089925248 2.5734840677494253 3.836065802213299 1.0387053871978371 0.3265560923975395 0.0075248679624052 0.2471994937249445 0.1132051672598368 0.1774767594454888 0.0081716861037673 +Protein insertion into er membrane 7 14 2.4482589223172395 0.0143548457235567 4.451456310679611 12.691747572815531 0.9645901040516046 0.3077872373135509 2.16101217194965 1.431147904526304 1.1733171268605926 0.305304417896891 0.0033195371374447 1.0 1.0 0.0017432511761074 0.0035298468720628 +Intracellular transport 182 619 2.445749745452608 0.0144551295957902 120.90291262135922 544.3956310679612 0.5500812282996078 0.6924011803517542 31.43517433849213 53.582766758854405 1.193070641867047 0.396756529943003 1.829571839935736e-11 0.0646169249599543 0.0074806282710218 3.2853488190859216e-06 2.1098861710295057e-11 +Regulation of mitochondrion organization 23 54 2.436978438423129 0.014810562445553 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0008241192963923 0.0959451239548942 0.091109134162985 0.018133097015229 0.0002974668071688 +Phosphatidylglycerol metabolic process 8 14 2.435666801039889 0.0148643696082548 3.7572815533980584 10.78640776699029 0.7074456860764219 0.3298030384317407 2.521619218643941 1.658461595229837 1.2128783939533223 0.2875854965146425 0.0296850028190536 1.0 1.0 0.1219531221716571 0.031065887399213 +Calcium ion transmembrane transport 15 44 2.4111542273122075 0.015902122379469 10.5 40.51456310679612 0.3400819096715784 0.5565528717247777 4.784430655681941 4.7513188310580725 0.9547513033794968 0.3464854172738558 0.0106643485758407 0.4657724234841013 0.1338452366906126 0.3977591424779263 0.0119101390989942 +Glycosylation 21 54 2.410520514542912 0.0159297754319731 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.0109902620007152 0.537249604550818 0.2041228743310066 0.0169952178401221 0.0123993048317629 +Plasma lipoprotein particle clearance 6 13 2.4081769110184257 0.0160324099314721 2.8033980582524274 11.597087378640778 0.2841472336869506 0.2922439265613805 1.7215617505529983 1.5431625772865891 1.3638326625090953 0.2354738993646769 0.2487525021118799 0.0901405579438761 0.1758008751515455 0.0834574734746242 0.2539261987860491 +Regulation of vacuole organization 5 12 2.405150995865463 0.0161657847885132 2.8567961165048543 11.82766990291262 0.1258946546155446 0.4588976974701806 2.33512175670257 2.002889031763913 1.0406614763927915 0.2804453828965037 0.1680095247635161 1.0 1.0 0.6691111110298131 0.1740747384317906 +Regulation of protein exit from endoplasmic reticulum 6 10 2.402362000166505 0.0162895794689776 2.487864077669903 6.131067961165049 0.614536574202818 0.458469843561175 1.597129798474628 1.7824129563144424 0.9381550143256092 0.3206976005104832 0.0137214676098665 1.0 1.0 0.0834574734746242 0.01439805670462 +Bone morphogenesis 4 9 2.393043309053471 0.0167092686027514 2.3737864077669903 7.519417475728155 0.7918915806069479 0.3290665752918499 1.3241931901591228 1.4011478132752644 1.0549507058478411 0.2731796281548322 0.0628856072356096 1.0 0.3530974878629287 0.2978006616879862 0.0660317196551079 +Neuromuscular process controlling balance 4 13 2.392189700617299 0.0167481833974274 3.8810679611650487 11.723300970873789 0.1269749302219408 0.3318237886495486 1.6788029789058698 1.2889149409291965 1.4027465363164735 0.2954189115293261 0.0059488175873696 0.1114021565620111 0.0016986126979642 0.0217985290060267 0.0063149437065281 +Cellular ion homeostasis 53 101 2.384682612281296 0.0170938618525637 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 4.703038941517671e-05 0.0389686958996075 0.1223228606683068 0.0338306149356432 2.383355120642992e-05 +Sterol biosynthetic process 10 24 2.382725316996397 0.0171850118015752 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 6.118264090575949e-05 1.0 0.3655284832956332 0.0053616069246772 6.895819454254321e-05 +Modified amino acid transport 4 7 2.379514309900743 0.017335469921778 2.029126213592233 5.587378640776699 1.6181581718562612 0.1578136127091599 1.2124460606928238 1.444653995706506 0.7704353439327314 0.2037484924456972 0.2487525021118799 0.0901405579438761 0.1758008751515455 0.0834574734746242 0.2539261987860491 +Negative regulation of transmembrane transport 8 23 2.361681806846881 0.0181922492266695 4.915048543689321 20.038834951456312 0.539232326403696 0.5077941070021844 2.6236539308948164 2.892649976298608 0.8428552268580063 0.3052620790205636 0.1919877891471458 0.2613604367755145 0.0235138787886837 0.0691718370159023 0.1996805126630332 +Purine containing compound transmembrane transport 5 10 2.36091480979459 0.0182299178270879 3.6432038834951457 8.228155339805825 0.8480777288434221 0.3004167480224937 2.0847056152178514 1.431742605530374 1.2278207398320582 0.2967021731271802 0.00356078515082 1.0 1.0 0.0439142352380576 0.0037486095651754 +Atp synthesis coupled electron transport 11 41 2.3593863905892767 0.0183051849139317 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 0.0003121321872988 0.0058176934433743 0.0008977570976206 0.0027518908513611 0.000355309503172 +Cartilage development 7 19 2.358997908774618 0.0183243590297708 3.932038834951456 14.283980582524272 0.7074320636322524 0.4287139668901396 2.125947582774665 2.5119975572795252 0.8798730191625526 0.3016172221818579 0.0700194356379938 1.0 0.5863803216648996 0.3793726701067281 0.0747071460891875 +Phospholipid transport 7 18 2.3581911840157668 0.0183642323405355 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0962196654305933 1.0 1.0 0.1257511849434855 0.1007202116491234 +Protein o linked glycosylation 4 16 2.352162487683235 0.0186646196394364 4.002427184466019 14.800970873786408 0.6110837568553249 0.4900688525596084 2.2082136900690967 2.0631296400791257 0.818007769485416 0.3069438623146977 0.1368116694516355 1.0 0.4242240140575919 0.048897845662748 0.1427791401704325 +Amide transport 19 37 2.3454215681157207 0.0190055767974133 9.512135922330096 37.99757281553398 0.8625203235532012 0.4243895840783888 3.9342099663331425 4.541875701235624 0.963016155404646 0.3369249994514658 0.2113384627929299 0.4783938870567416 0.3803883597337516 0.1154859850799389 0.2229968407150887 +Atp transport 5 6 2.343429735927691 0.0191073608831668 3.4805825242718447 6.233009708737864 0.5838786306840471 0.3211615036091749 1.83337760624298 0.8807971179633459 1.3636108978108328 0.3170401972517012 2.6683987719570872e-05 1.0 1.0 0.0188064524051028 2.858966188275996e-05 +Membrane fusion 21 48 2.341834797548989 0.0191892066459899 11.592233009708735 41.140776699029125 0.24764888033976 0.6429045305046197 5.404397514006145 5.499742922380336 0.8586283816511532 0.3399356769366213 0.0422704961666863 1.0 0.6629984443692342 0.2876446172469952 0.0201706348246818 +Endoplasmic reticulum calcium ion homeostasis 6 8 2.336582631451772 0.0194608964374036 3.412621359223301 8.468446601941748 0.7163576234395546 0.3718536853795897 2.0059706805420334 1.5568434939403433 1.1166052913833018 0.3156746531372333 0.0033195371374447 1.0 1.0 0.4172977923286156 0.0035298468720628 +Erad pathway 17 43 2.32591474703266 0.0200230991599561 9.883495145631068 38.19174757281554 0.3304224870610107 0.6151102195901742 4.326035362628732 4.084618299759124 0.8776780132973124 0.3415212956260079 0.0403781767245565 0.3656394840654732 0.6060556355956216 0.0288939483426972 0.0180158647957279 +Regulation of leukocyte mediated cytotoxicity 5 8 2.325125468494298 0.0200652521728252 2.5825242718446604 7.334951456310679 0.4511695306521209 0.4227043221453989 1.4499700153890709 1.2995300672557608 1.082342679990832 0.3098039206468536 0.1053751065738953 0.1071891284628969 0.2070995190727305 0.4452488918515388 0.1088149775417643 +Negative regulation of neuron apoptotic process 6 27 2.324322716018445 0.0201082042122171 5.757281553398058 26.135922330097088 0.5817179538337637 0.4854643114827585 2.727835727399863 2.4377633537168184 0.9011837787919588 0.3153742372034477 0.1076439852368788 0.0592812765226785 0.1932167773678115 0.1462824662633921 0.11375295949697 +Metal ion homeostasis 43 92 2.318154219161766 0.0204409411025874 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.0001521895818196 0.0346905972569956 0.1089652119169875 0.0551845763489856 0.0001919700123909 +Mitochondrial electron transport cytochrome c to oxygen 5 7 2.3109988966880803 0.0208329158359428 2.6189320388349513 6.021844660194175 0.7576771538928655 0.3133819177040797 1.4641113893518565 0.9306060741204804 1.2097595052740109 0.2966582872605096 0.0019008813135546 1.0 0.1094892401774078 0.00262770885776 0.0020033682110678 +Iron ion transport 8 12 2.296420346987653 0.0216518586900478 2.8762135922330097 9.3252427184466 0.6984692822717036 0.3339124009240178 1.7603279794274296 1.4434464182805606 1.1549328537786283 0.2828654848729625 0.2092417220825769 1.0 0.2732850813359189 0.1899587232036964 0.2151867556135544 +Mannosylation 3 7 2.2963757962860334 0.0216544036489434 2.6262135922330097 6.966019417475728 0.6104715271961744 0.3620085753936749 1.5520397580890246 1.435949900284761 1.1183031747274563 0.2897179829421447 0.0382192701106142 1.0 0.2297987482657219 0.1383652025719425 0.0399552443236748 +Regulation of glycoprotein metabolic process 5 12 2.293601306564169 0.0218134102815126 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.0429593131307029 1.0 1.0 0.4972078859355511 0.0448872219881859 +Cerebellar purkinje cell layer development 6 10 2.291904647939545 0.0219111460044734 2.191747572815534 6.961165048543689 0.8392766864609098 0.2843914142715297 1.2383946131318218 1.2878998490964535 1.1730456034866912 0.2696789702944095 0.0093478027703867 0.0814971443263516 0.1596960736798767 0.0007869115437374 0.0098193480789534 +Export across plasma membrane 6 8 2.279597057014301 0.0226315976715012 3.342233009708738 8.672330097087379 0.659462409318522 0.3364871063656119 2.046038764373277 1.5847916183398325 1.1961171404298503 0.3001696886640556 0.4253564839389538 1.0 1.0 0.5213399099817488 0.4325786085596129 +Regulated exocytosis 14 41 2.278170401655826 0.0227164270180424 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.1312617712337785 0.4396258949303272 0.6943670866160305 0.5707162676561247 0.1395736955123197 +L amino acid transport 11 12 2.276098089148943 0.0228401394315727 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.2219477285215065 1.0 1.0 0.1988041978590851 0.228153712059568 +Mitochondrial electron transport ubiquinol to cytochrome c 1 5 2.274629442004945 0.022928168390208 1.5048543689320388 4.206310679611651 0.8658650693935839 0.2665349265497743 0.9514810775456936 0.7935779738409815 1.3072925004771625 0.2886561243868636 0.0660756735344618 0.0007650215967213 0.0031504918831051 0.0188064524051028 0.0677640175569944 +Lipid localization 40 90 2.2669634771736464 0.0233924569258057 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 6.942453937484916e-06 0.2792677388815299 0.1632643902509063 0.0075338259116371 9.008924178648873e-06 +Low density lipoprotein particle clearance 5 12 2.2666572097109987 0.0234111743128078 2.628640776699029 10.633495145631068 0.2652848599989675 0.2775304047094778 1.52978680445189 1.394909057645927 1.3932465899654711 0.2286950604253255 0.1772895401336459 0.0727733471903131 0.1432798584585485 0.0561137872346343 0.1812716861639223 +Ensheathment of neurons 17 30 2.265782426422956 0.023464707877371 7.109223300970874 25.317961165048544 0.4295341143396002 0.5630321678871352 3.545161118750975 3.535996271146197 0.857834731365342 0.3150461050621543 0.0598046404363514 1.0 1.0 0.1646032801604304 0.0639136560040006 +Metal ion export 6 8 2.264772862298412 0.0235266215709752 3.779126213592233 8.553398058252426 0.5059205316086877 0.4155863674545267 2.112664358767855 1.499049247815051 1.150738830143596 0.3315496346975708 0.0768164760449794 1.0 1.0 1.0 0.0794376465838621 +Mitochondrial cytochrome c oxidase assembly 6 7 2.26452450596457 0.0235418742684594 2.344660194174758 5.764563106796117 0.9954600272926416 0.2681565835601643 1.449018962088891 1.4364892997002987 1.2150903662861117 0.2820677765861404 0.0192115706028201 0.0987043131013681 0.191600110602388 0.0983610682747182 0.0201372619620155 +Mitochondrial calcium ion transmembrane transport 6 10 2.259452594770225 0.0238552459433118 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.0006988566317415 1.0 0.1432798584585485 0.3247468214281712 0.000745702459351 +Oxidative phosphorylation 19 66 2.250851536743748 0.0243949421075204 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 8.268598908684947e-07 0.0002282660183357 1.7822031869587478e-05 5.76372147463742e-06 1.0330398719432656e-06 +Ubiquitin dependent erad pathway 15 38 2.244427814120728 0.0248048885959175 8.635922330097088 33.189320388349515 0.3115013568224312 0.6374197165259132 3.8558329126504 3.468034686486237 0.8005779700625321 0.3301326985720395 0.0306686052841368 1.0 1.0 0.0386631533679294 0.0120798089995662 +Regulation of cell killing 5 9 2.239847259076424 0.0251008405902881 2.844660194174758 8.366504854368932 0.4041102541319114 0.4507662844932221 1.5842506516490529 1.3031494402288128 1.0522249449787806 0.3118972087461248 0.1722386963203812 0.1321770275159086 0.2518545844225215 0.5213399099817488 0.1773693871336699 +Regulation of release of cytochrome c from mitochondria 7 12 2.238969603243755 0.0251578940228498 3.6310679611650487 10.805825242718448 0.7924389389582319 0.4006886058463786 1.815469081442188 1.3603843861930187 0.9712392086725492 0.3199873643457663 0.0031187173192781 0.1362745587685063 0.2590666885683055 0.0383377547470353 0.0005860509424053 +Autophagy of mitochondrion 15 41 2.233509764667475 0.0255153471204743 8.643203883495145 32.55582524271845 0.5912176019297528 0.507260115546458 3.9310041488944902 4.499114265424183 1.01585008111736 0.3556742421157408 0.0009341352892438 1.0 0.5213291194813008 0.1123101919918835 0.0002772159414699 +Mucopolysaccharide metabolic process 4 11 2.230513465138068 0.0257133745449236 3.400485436893204 8.912621359223301 0.5894446998893683 0.2689339883290864 1.6227448151896249 1.7256308603927724 1.433353391777711 0.275728271795533 0.0628856072356096 1.0 1.0 0.0230341265569123 0.0660317196551079 +Amyloid precursor protein metabolic process 7 20 2.217007421800479 0.0266225843678149 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0044098840567157 0.2291240669446297 0.0978881295505725 0.0104048104957299 0.0048031771903066 +Endochondral bone morphogenesis 3 8 2.216496267336748 0.0266575332380036 1.6480582524271843 5.594660194174757 0.7038217123315962 0.3729755664973352 1.1864612949328115 1.0785960989759678 0.9833570305213049 0.2787707264141815 0.0480149363567744 1.0 0.2445730022705269 0.1552222190730896 0.0501437556032915 +Calcium ion transport 20 61 2.211178506595259 0.0270234781602418 14.359223300970871 56.12135922330097 0.5117941214501432 0.5203785154770082 6.100858397237751 6.232924643281249 1.067298802513521 0.3756526252141436 0.010402492987284 0.5673144818966444 0.0892949185260018 0.4235513457781087 0.0053338056052486 +Inorganic anion transmembrane transport 7 10 2.2057980251273603 0.0273981446447197 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.160353317011437 1.0 0.031373049189738 0.1552222190730896 0.0501437556032915 +Nuclear envelope organization 15 32 2.2028792556529813 0.0276032600944455 8.555825242718447 29.70873786407767 0.3742592988081523 0.5658154731413123 3.620906131367995 3.382223856109787 0.8839532199066901 0.3277754788938732 0.0962196654305933 1.0 0.3896854720293997 0.3513790442708272 0.1007202116491234 +Transition metal ion homeostasis 14 29 2.192481783544108 0.0283447370288685 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.0140444177310871 0.0062418878726007 0.0415809882988902 0.0444212272681039 0.0152888106516868 +Sphingoid metabolic process 4 6 2.1817231443698466 0.0291299717296711 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0008708072207696 0.0461123069087121 0.0921025797166938 0.0231366382468947 0.000918782674844 +Respiratory electron transport chain 15 54 2.180699985913772 0.029205614094895 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 1.1601614339081588e-05 0.0103010078837755 0.0003120858048586 0.0001051927101865 1.3854465326814324e-05 +Protein localization to vacuole 8 25 2.177296610774435 0.0294584439038281 5.20873786407767 20.24757281553398 0.5437651170857908 0.3970016112497027 2.9079938968471533 3.678442701839641 1.178287503307516 0.309681546976434 0.0543699534322455 0.236404668572991 0.4242240140575919 0.048897845662748 0.0575078377952935 +Pigmentation 13 22 2.176356684091841 0.0295286000581416 4.621359223300971 15.95388349514563 -0.0588929193094965 0.6733797186312787 2.688943578803346 2.737781233684313 0.6910396485478176 0.2765638482400957 0.968329278828511 1.0 1.0 1.0 0.969894286058864 +Maintenance of protein location in cell 9 25 2.1714592559676964 0.0298964738466989 4.963592233009709 20.74757281553398 0.5138976626555444 0.4828559702191822 2.90064182866346 2.9061984196552437 0.947299732036647 0.3164077327541715 0.0083585032956262 0.2068720246493716 0.0803922289273931 0.0304079267330467 0.0090060858517451 +Xenobiotic transport 4 6 2.1712315714733905 0.0299136719495134 1.693827160493827 4.08641975308642 0.9732407293076591 0.2870054952103567 1.1547374966527622 1.4159369001791104 1.1259148135419206 0.2680466782257013 0.2487525021118799 1.0 1.0 0.3879443652654283 0.2539261987860491 +Alcohol biosynthetic process 14 38 2.1615974227583727 0.0306492202937795 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 0.0002682918795274 0.0643379769398232 0.0526082110144703 0.0012809712291409 0.0003079783514064 +Cellular transition metal ion homeostasis 12 24 2.160667047182625 0.0307210681561453 5.893203883495145 20.42233009708738 0.9608801516152976 0.3243056832171095 2.800529150274697 2.6932649561537056 1.130076157725316 0.3011842711337114 0.0353348681692099 0.037406554204333 0.1290920553826253 0.0723728978816966 0.0377265240835835 +Lysosomal lumen acidification 5 6 2.155254183913245 0.0311419489271114 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.0013168186836578 0.0011617774889038 0.0047533286028597 0.0020064706347618 0.00138858926748 +Intracellular lipid transport 6 17 2.1552504236055228 0.0311422430237673 3.2475728155339807 12.529126213592232 1.0333463606041455 0.2805251274605093 1.854375285913986 2.478377603832177 1.0146678848168829 0.2521579143644115 0.0713523815072877 1.0 1.0 0.0449350347407693 0.0743636419116672 +Negative regulation of ion transmembrane transporter activity 3 11 2.1531373219543246 0.0313078878388635 3.817961165048544 11.861650485436892 0.3764600221454999 0.5118077234396127 2.3889648646862596 1.939068236399221 0.964288359393085 0.3191649145735881 0.0779463222258674 0.1484538203623246 0.0420348553288257 0.0484311287755044 0.0811948723624906 +Membrane docking 11 32 2.1354857480388127 0.0327213531140397 7.973300970873787 28.83252427184466 0.3013065671948621 0.638505559524285 3.967313754164099 3.197937811998676 0.8147042438070861 0.3288047187933706 0.1067287302582427 1.0 1.0 0.4934040207883591 0.1122344780520613 +Negative regulation of cellular response to growth factor stimulus 6 14 2.133988210247612 0.0328437459159645 3.587378640776699 10.54368932038835 0.1463800751641292 0.5765787384277418 2.347201581543042 1.7447658146978844 0.8277871796053454 0.2976593853511285 0.6993287512285102 0.2106238865638343 0.3837329617110586 0.7074631838133625 0.7068783404938086 +Protein retention in er lumen 4 5 2.131395012889911 0.0330566133892518 1.203883495145631 3.203883495145631 1.1364527439994954 0.2609157960586762 1.0226486010276945 1.0226486010276945 1.138989616014889 0.2624735143617788 7.258321234335445e-05 0.0279227766388577 0.0013376518177504 0.0002661275452166 7.675515939222757e-05 +Maintenance of protein localization in endoplasmic reticulum 4 5 2.131395012889911 0.0330566133892518 1.203883495145631 3.203883495145631 1.1364527439994954 0.2609157960586762 1.0226486010276945 1.0226486010276945 1.138989616014889 0.2624735143617788 0.0003135208860554 0.0370595951599339 0.002465796513642 0.0007187465088185 0.0003311660608568 +Negative regulation of leukocyte mediated immunity 4 7 2.130883716513247 0.0330987231940056 1.4684466019417477 5.152912621359223 1.0166590601943912 0.2872549002772236 1.1850502896064032 1.2860024091145663 0.9722873313503664 0.2687277537722931 0.0768164760449794 0.0944323477659319 0.1837383274168749 0.4028006685093745 0.0794376465838621 +Reactive nitrogen species metabolic process 5 17 2.1301286206843444 0.0331609960187753 3.9805825242718447 16.550970873786408 0.5187061899010498 0.4616229774504417 2.0608725766457097 1.6501909360329357 0.9419567550357958 0.306935586730602 0.0177131525310705 0.1878492321971458 0.3467918934582977 0.2887846572413305 0.018870184963526 +Negative regulation of autophagy 8 26 2.1212317821537434 0.0339023019209667 5.063106796116505 24.313106796116504 0.449887145270975 0.5377284095479077 2.9855473971181983 2.929018368027943 0.8516059018543028 0.3205218740462018 0.0407196130241837 0.2718096468929847 0.1355867800667393 0.2210522410556178 0.0434273695437325 +Mitophagy 7 18 2.1195223713626694 0.0340463451739885 4.174757281553398 14.737864077669904 0.7026339988268726 0.4220360300693995 2.5842209186951752 2.0501535109396865 0.9566781806577936 0.318538155650451 0.0031187173192781 1.0 0.2590666885683055 0.1724444479617574 0.0033472823991884 +Glycolipid catabolic process 3 7 2.1181449804448853 0.0341627911219653 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 0.0019008813135546 0.0550816697898294 0.1094892401774078 0.0328731354880699 0.0020033682110678 +Maintenance of protein localization in organelle 7 18 2.1160814916713617 0.0343378773259219 3.866504854368932 15.29368932038835 0.5637691386290394 0.4400793840085654 2.3676920099244176 1.9777055894707407 0.9564449590017818 0.2977236914910925 0.004326259109494 0.1444128696349771 0.0398064357050217 0.0449350347407693 0.0046379242911556 +Protein localization to golgi apparatus 5 11 2.114958456251216 0.0344334882368664 3.2888349514563107 9.216019417475728 0.6251969398118403 0.4536668430035578 1.8319101394901296 1.828691420197124 0.8916256553809645 0.3040795237699089 0.0296850028190536 1.0 1.0 0.1219531221716571 0.031065887399213 +Phosphatidic acid metabolic process 5 8 2.107738566350657 0.0350536093929148 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.1263793020712777 1.0 1.0 0.4718643991127431 0.1303826157459173 +Amyloid precursor protein biosynthetic process 2 5 2.1072659246120424 0.0350945353086886 1.529126213592233 4.050970873786408 0.5724883308647799 0.4003128139433519 1.0007891127244537 1.1319816926742772 1.117383900072293 0.3129811194531851 0.007414327658262 1.0 1.0 0.1981219124770219 0.00771353919978 +Vesicle docking 8 18 2.106559238388348 0.0351558031540317 5.046116504854369 16.300970873786408 0.2955335573812314 0.5566344803804099 2.726231700974349 2.3037957343391864 0.8857805503827542 0.3078464388536641 0.1680095247635161 1.0 1.0 0.2978006616879862 0.1740747384317906 +Positive regulation of mitochondrion organization 10 26 2.105224601086234 0.0352717617694233 6.235436893203883 22.393203883495147 0.6669540243221574 0.4355223453199826 2.7589935116766484 2.962672702300372 1.01251720769805 0.3295170825531805 0.0127346112580639 0.2217755071466549 0.0919415891551245 0.0390247080582918 0.0038055285280442 +Negative regulation of ion transmembrane transport 4 16 2.10038666098137 0.0356948414512414 3.851941747572816 15.769417475728156 0.5591127282390159 0.4901790245134628 2.193308693671018 2.0873490063373943 0.8555485550788116 0.3017041398323139 0.0628856072356096 0.1916891885455893 0.0091243340822671 0.0230341265569123 0.0660317196551079 +Regulation of mitophagy 4 8 2.096267845775894 0.0360584374112467 2.033980582524272 6.730582524271845 0.7938894190377023 0.2859156513857533 1.5052692819802862 1.0417203147023346 1.2011910390869405 0.2760404746280959 0.0019008813135546 1.0 0.1094892401774078 0.0328731354880699 0.0020033682110678 +Membrane protein proteolysis 6 12 2.095561162234785 0.0361211375005257 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 0.0410408850871989 1.0 1.0 0.2526409373615763 0.0432084674189714 +Calcium import into the mitochondrion 4 7 2.0955150873369037 0.0361252286947697 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 0.0019008813135546 1.0 0.1094892401774078 0.2550529546148332 0.0020033682110678 +Cytosolic calcium ion transport 9 25 2.093142509475081 0.0363364349633312 6.567961165048544 23.944174757281555 0.4634706877593821 0.4616211122842976 3.323605294530572 2.8902732844456565 1.0331628024603872 0.3216839736311487 0.0202391625142957 1.0 0.1967082241040804 0.6143274539738884 0.0219681008445407 +Release of cytochrome c from mitochondria 7 16 2.092469667591394 0.0363965223777256 4.684466019417476 15.262135922330096 0.4193082596791256 0.5083980701856582 2.17386315704194 1.8032396146210607 0.903472393069956 0.3097282682815904 0.0022588883215701 0.1683799151698467 0.3143397790261298 0.0678108138951911 0.000479523089417 +Proton transporting two sector atpase complex assembly 4 6 2.0923927229011623 0.0364033992322063 1.7432098765432098 4.6839506172839505 1.079697689782964 0.2705190312822739 1.1688274457451555 1.1775111637565157 1.0292886485906785 0.2668917829180481 0.00356078515082 0.0639684350193291 0.1265462710440741 0.0439142352380576 0.0037486095651754 +Apoptotic mitochondrial changes 13 34 2.0837989643073924 0.0371784575962197 8.33495145631068 31.9126213592233 0.3104951463965997 0.5709370276570955 3.5539451273925566 2.6332703138780773 0.8593316992754738 0.3196919958634499 0.0026653697092723 0.2956314809635333 0.5119234098565739 0.0333870553509734 0.0008357361148287 +Negative regulation of mitochondrion organization 9 19 2.080450293500108 0.0374842503180186 4.148058252427185 15.354368932038836 0.2912247280514271 0.5498435069117807 2.316031321892106 1.7545102322731794 0.8222100433915656 0.2937386563478433 0.0013880477544212 1.0 1.0 0.2166326226637888 0.0015071148532441 +Positive regulation of cell killing 4 7 2.0711658960402795 0.0383432954722227 2.344660194174758 6.594660194174757 0.4156629456801037 0.4127481983530973 1.3626949423444794 0.9467730739010484 1.1172564974004802 0.3098028662961327 0.0768164760449794 0.0944323477659319 0.1837383274168749 0.4028006685093745 0.0794376465838621 +O glycan processing 2 5 2.0643257514893216 0.0389868410038336 1.8762135922330097 5.029126213592233 0.779006640385936 0.3319918611732407 1.1540209287066336 1.1758600296433448 1.0243123329907684 0.2736840802111854 0.1053751065738953 1.0 1.0 0.0195244436529747 0.1088149775417643 +Cartilage development involved in endochondral bone morphogenesis 2 5 2.0624243734644523 0.0391673507898284 1.1796116504854368 4.143203883495145 0.7350810718669425 0.3586352265306819 0.9959977407956764 0.3502806464066411 1.0070814564726387 0.2818242420799869 0.0324301480805536 1.0 0.1349531130589082 0.307957256786686 0.0336357980244025 +Golgi ribbon formation 3 8 2.062390061701384 0.0391706147300547 1.7839805825242718 5.368932038834951 0.46476608528316 0.5256549988553783 1.2441847955381082 1.636894355572042 0.8281537892225903 0.307775974030476 0.1102882610537575 1.0 1.0 0.2550529546148332 0.1129571724371578 +Sensory perception of light stimulus 4 19 2.0579671642364725 0.0395932855313143 5.009708737864078 15.96359223300971 0.918103407248628 0.3572194322029593 2.4583724414330383 3.147064390877318 0.9947617981182544 0.3055434177582076 0.2090275779542802 0.2683427616475903 0.4724360815693985 0.2146915796551673 0.2171967394237606 +Endoplasmic reticulum to cytosol transport 9 16 2.051296129233622 0.0402381172095385 3.941747572815534 12.330097087378642 0.2271948370905603 0.5066515511983778 2.014873060727058 1.3266378374443757 0.996451663109182 0.3144730092656803 0.0083546496185296 1.0 1.0 0.0038040834633598 0.0088588626715525 +Synaptonemal complex organization 3 7 2.0472939764839477 0.0406292289727812 1.470873786407767 6.174757281553398 0.723394588880887 0.4361908449153728 1.1810092004903878 0.7330900746788283 0.8281604841906476 0.2971095774097388 0.0800399185240521 1.0 1.0 0.2175647207167039 0.0820486275159116 +Regulation of blood pressure 8 23 2.0383523028451926 0.0415147127059334 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0202624952873958 0.2400196775334175 0.107004894081217 0.0515621560092188 0.0217195139585283 +Lysosomal transport 18 52 2.0336480079481283 0.0419870977430099 10.274271844660197 41.317961165048544 0.2711798693300527 0.4597127484771267 4.560810075793522 6.516846556965687 1.3243780303643906 0.3539546843782676 0.0109599402860589 0.3893684484717567 0.2640710535308501 0.4634409820203541 0.0121001929279061 +Chloride transmembrane transport 4 7 2.0212704117338234 0.0432517803174983 1.9271844660194175 5.497572815533981 1.0121969151812915 0.2503571453769561 1.6864793094247907 1.5080669592016671 1.1003731395705292 0.2453144412674818 0.1949057699825326 1.0 0.1515272625734178 0.3411306657380243 0.0468003866103798 +Respiratory chain complex iii assembly 2 5 2.011424604032233 0.0442806266862558 1.8470873786407769 5.160194174757281 1.360931378136811 0.1995688008303064 1.0650749835200868 1.2360161344522411 1.0120439004969468 0.2366879233397748 0.0051238819070113 0.0370595951599339 0.0743799864466655 0.0007187465088185 0.0053334351931861 +Fatty acid transmembrane transport 3 8 2.006159056555803 0.0448392806467521 2.3519417475728157 6.720873786407767 1.487456141723218 0.1763040127694548 1.5547987465385102 1.1092073674791965 0.7935702169981724 0.2103298472796338 0.1102882610537575 1.0 1.0 0.0328731354880699 0.1129571724371578 +Antigen processing and presentation of endogenous antigen 4 7 2.0000156211193465 0.0454985771240448 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 0.0046737877195888 1.0 1.0 0.307957256786686 0.0049176108076387 +Antigen processing and presentation of endogenous peptide antigen 4 7 2.0000156211193465 0.0454985771240448 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 0.00356078515082 1.0 1.0 0.290751966651369 0.0037486095651754 +Oligosaccharide metabolic process 3 6 1.999988554187172 0.045501499851499 3.0606796116504853 6.179611650485437 -0.0148577354153068 0.2267163537664357 1.4017006052191363 1.1242135739548185 1.7186048285621385 0.2671195008920222 0.095439119896664 0.1029565435856987 0.0202898922491691 0.1060727287920157 0.0986013223955862 +Lipid biosynthetic process 63 163 1.9946114411355989 0.0460852747786328 38.012135922330096 141.7257281553398 0.5620793375816577 0.4367444072022249 15.729119254593195 17.314902336322657 1.553306672697969 0.3832082090559359 1.584776448700999e-07 0.8710728288690597 0.7816800065592221 0.015151225604853 2.4039114387805057e-07 +Positive regulation of chemokine production 1 7 1.992430514190992 0.0463238421051452 1.703883495145631 7.002427184466019 1.1308330497685224 0.261365768238967 1.2206493839204828 0.948936007151574 0.9251734036107908 0.2478284645013121 0.3029931084616707 0.1029565435856987 0.1993869387044997 0.4314443861210575 0.3089323218960526 +Chemokine production 1 7 1.992430514190992 0.0463238421051452 1.8810679611650485 8.337378640776699 0.9152793985046536 0.327029475914965 1.2820382835273771 1.4780796128991345 0.9350060766690576 0.2657366976150246 0.4583279921498481 0.1403531442218371 0.266209970857853 0.544318157098314 0.465786591734874 +Negative regulation of macroautophagy 5 13 1.9922816893061408 0.0463401595957757 2.657766990291262 11.342233009708735 0.5734063046472396 0.4235310399182105 1.9797182461289764 1.5349845399675808 0.9579244223739132 0.2955499758703153 0.0590668767933114 0.1362745587685063 0.2590666885683055 0.5329697587184232 0.0616223233666864 +Endothelial cell proliferation 3 17 1.991110820567036 0.0464687051173613 3.737864077669903 17.388349514563107 0.8369436650143091 0.4126693113525184 2.24564806763238 2.518795403681403 0.8441326938580735 0.2996825893791121 0.4666090710583638 0.2922756805728106 0.1554832015057707 0.1005919349614823 0.4777080304114748 +Ph reduction 7 15 1.990692589458863 0.0465146939243039 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0018025827173796 0.0075879492488378 0.0293903981750984 0.0294507732567689 0.0002995500484788 +Mitochondrial atp synthesis coupled proton transport 5 11 1.9901560910567315 0.0465737435225783 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 0.0012658498659003 0.0031646532309382 0.0126574737404708 0.0087554356838108 0.0013491401517078 +Chondrocyte differentiation 5 13 1.9785268997544776 0.0478692970573504 2.6650485436893203 9.92233009708738 0.2607944337218785 0.5422880967404352 1.6748979819889611 1.9850867305810889 0.8369685556388278 0.2884880468615965 0.0543699534322455 1.0 1.0 0.7538310034115123 0.0575078377952935 +Protein localization to organelle 114 360 1.974906914783426 0.0482787125530381 67.3495145631068 323.95873786407765 0.2673038377247629 0.817015428896562 19.766210620364816 30.728939371736654 0.7017218037327799 0.31039729979455 6.8112181327499785e-06 0.0540877748662387 0.0228026708891479 0.0008084296926597 5.397537338872593e-06 +L alpha amino acid transmembrane transport 9 10 1.9727780663515395 0.0485208531594443 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.2092417220825769 1.0 1.0 0.1899587232036964 0.2151867556135544 +Protein hydroxylation 7 18 1.9714501150928545 0.0486724135999769 5.04126213592233 14.87621359223301 0.7765678108992397 0.4273021352291809 2.482119818897232 1.8660787070180411 0.9906439819977368 0.3285418073460514 0.0049505599365773 1.0 1.0 0.4452488918515388 0.0052582215982291 +Neuron apoptotic process 12 56 1.9678664314997432 0.0490834080942563 11.191747572815531 49.65533980582524 0.9007291731588002 0.4299023129629146 4.0102574614548505 4.518854312987721 0.9862249081516458 0.3541854094791909 0.0254217483832197 0.0322247907180468 0.1702274141564555 0.0274278527807438 0.0281196880783471 +Lipid translocation 4 7 1.964802184188007 0.0494371373147699 1.720873786407767 4.390776699029126 0.721199302569061 0.3015554657161993 1.2968412758505727 1.7626690867431634 1.2167340583298332 0.2614747358309583 0.0859119874297797 1.0 1.0 0.4172977923286156 0.0888008652079453 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..97d0232a22ee733a0792878234113a9120953206 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 6577, + "title": "Average number of proteins per term", + "value": 20.8823171658811 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8c3e9e352248914d2567dbd67728c1529aa459bd --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7560d18da2fdf8c6c7f3d1c566286bc55b23bc10 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1832 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.5464197318266925 6.505996789516746 7.717987434600111e-11 5.076119113352682e-07 5.076120401506492e-07 245 Q9UDW1,P06756,O43707,P36543,O60830,P52789,Q9NS69,Q99595,O75027,O14678,P00846,Q9C0H2,Q9HC07,P46934,O75964,Q9Y584,O43808,Q9H2D1,O14925,Q9HD47,P22413,Q96ES6,P62942,Q7L0J3,Q99623,Q8WWC4,Q13423,P50416,P13073,Q9UBX3,P21796,Q9UHG3,Q9H2V7,O75844,P45880,Q9BSK2,Q70HW3,Q7KZN9,P33527,P24539,P23786,P33897,Q9H2J7,Q8N4V1,Q15629,Q8TAD4,O00400,Q8TB61,P04062,P00403,Q8WTV0,P27105,Q9Y277,Q9HD20,O75746,Q8N1S5,Q96PU5,Q07820,P12235,Q9Y619,Q13586,P51797,Q8NE01,Q15388,L0R6Q1,Q9Y6M7,P05067,P38435,Q8IYU8,P12236,Q03518,O43615,O95202,Q9NW15,Q9BQT8,Q16625,Q6P4Q7,P30825,Q9NV96,O75381,P23634,Q9BPX6,P56385,O14548,Q15043,P20020,Q06787,Q96RD7,P06576,P05141,P16615,Q9HC21,P49755,Q6NUK1,Q9NWR8,P51790,Q99758,Q9NRA0,Q06481 99 +Mitochondrion organization 0.5186052309991981 6.162477854113121 7.161534925632761e-10 4.710130436153063e-06 2.190635052534909e-06 211 Q9Y2R0,O75880,O60830,Q8N4H5,P52789,Q9NS69,Q8N2A8,Q9UDX5,P11233,Q99595,Q9NUQ9,O43676,Q96TA2,Q9Y6C9,Q96A26,Q69YU5,Q9Y584,O14925,Q96CU9,Q99623,P03886,Q7L592,Q8WWC4,Q9UG56,P21796,Q9UJZ1,P14406,P49257,Q9H061,Q9NVH1,Q9UII2,Q9Y512,O14737,P45880,Q9BSK2,Q9P0J0,Q9NQ88,Q86Y39,Q9H4A6,Q04837,P02545,Q13637,Q15070,Q16706,P51572,Q5XKP0,Q96E52,Q9BWH2,Q13505,P04062,Q9Y5J9,Q6DKK2,Q96RL7,O60313,O60220,P12235,Q9BUR5,Q15388,Q16891,Q9Y255,Q8N8Q8,Q9NVI7,Q9Y5J6,O95139,Q6UXV4,O43615,O95202,Q9H3K2,P27544,Q9NX63,O75153,Q9BUB7,Q9H300,O96000,Q9Y3D6,P30536,Q8NAN2,Q5T9A4,O14548,Q53H12,Q9Y5L4,P05141,Q9Y371,P53365,Q96I36,Q8IWA4,Q16543,Q10713,O00429 89 +Endomembrane system organization 0.5123570824373628 6.109533892148429 9.992253536608982e-10 6.571883565966718e-06 2.190635052534909e-06 198 Q8NHH9,Q8N1F7,Q5JTV8,O95197,Q15006,Q9P2W9,Q53FT3,Q96CP7,P49257,Q9Y3A6,O75844,Q8WTW3,Q12846,Q5JRA6,O43752,Q86XL3,P20700,P40616,Q00765,Q14108,Q12768,P33897,P61026,Q12907,Q9H4A6,Q8N4V1,P02545,Q15629,Q9BRG1,Q9NQC3,P61019,Q9H2C2,Q9HD42,Q6NUK4,Q96A33,P62820,O75955,P53350,O95295,Q9BTV4,P48729,O43681,Q8N5M9,Q14203,P61020,A0FGR8,Q96JH7,Q9NPA0,Q969M3,P78537,Q9Y3E7,O14964,O94901,Q9H267,P50570,Q14789,Q01082,Q15363,Q14155,O15260,Q9BRK0,Q9P0I2,Q7Z3D4,Q9UID3,P50402,Q12981,Q7RTS9,Q9BSR8,Q96ED9,Q9H6H4,Q9UH99,O95721,Q8TBA6,Q16739,P46379,Q9Y371,P16615,Q15643,P49755,O43760,Q9BTU6,Q9UP83,Q9P0T7,Q13190,O00429,P51790 86 +Ion transport 0.5167353486147949 6.06226858572246 1.3421483866543092e-09 8.827270990940322e-06 2.206827486400598e-06 230 Q9UDW1,P06756,O43707,P36543,O75027,P00846,Q9C0H2,Q9HC07,P46934,O75964,O43808,Q9H2D1,Q9HD47,P22413,Q96ES6,P07602,P62942,Q7L0J3,O15173,Q99623,Q8WWC4,Q13423,P13073,Q9UBX3,P21796,Q9UJZ1,Q9UHG3,O75844,P45880,Q70HW3,P08183,Q7KZN9,P33527,P24539,Q9H2J7,Q8N4V1,P53985,Q9NP58,Q8TAD4,O00400,O15439,P05023,Q8TB61,P98164,P00403,Q9H9B4,P27105,Q96QD8,Q9Y277,P02786,Q9HD20,O75746,Q8N1S5,Q96PU5,O43681,P12235,Q08722,Q9Y619,Q04656,P20674,O95563,Q13586,P51797,Q8NE01,P62258,P50570,Q9NZJ7,Q9UJS0,Q9NUT2,Q9Y6M7,P04083,O76024,P05067,Q9UM00,Q86WC4,P55011,Q8IYU8,P12236,O95202,Q9NW15,Q9BQT8,Q6P4Q7,P30825,P30536,Q02790,P23634,Q9BPX6,P56385,O14548,Q15043,P20020,Q06787,Q96RD7,P06576,P05141,P16615,Q9HC21,Q9NP80,Q6NUK1,Q9NWR8,O00429,P51790,Q9NRA0,Q96S66 104 +Ion transmembrane transport 0.5416947840591223 5.791395132318482 6.980413795932994e-09 4.5909127846399995e-05 9.18203630848566e-06 176 Q9UDW1,P06756,O43707,P36543,O75027,P00846,Q9C0H2,Q9HC07,P46934,O75964,O43808,Q9H2D1,Q9HD47,Q96ES6,P62942,Q99623,Q8WWC4,Q13423,P13073,Q9UBX3,P21796,Q9UJZ1,Q9UHG3,O75844,P45880,Q70HW3,P08183,Q7KZN9,P33527,P24539,Q9H2J7,Q8N4V1,P53985,Q9NP58,Q8TAD4,O00400,O15439,P05023,Q8TB61,P98164,P00403,Q9H9B4,P27105,Q9Y277,Q9HD20,O75746,Q8N1S5,Q96PU5,P12235,Q9Y619,Q04656,P20674,O95563,Q13586,P51797,P62258,P50570,Q9UJS0,Q9NUT2,Q9Y6M7,P05067,Q9UM00,P55011,Q8IYU8,P12236,O95202,Q9NW15,Q9BQT8,Q6P4Q7,P30825,P23634,Q9BPX6,P56385,O14548,Q15043,P20020,Q06787,Q96RD7,P06576,P05141,P16615,Q9HC21,Q9NWR8,P51790,Q9NRA0 85 +Membrane organization 0.4985071352308986 5.669818065097187 1.4294923690683751e-08 9.40132942654444e-05 1.566961885336734e-05 254 P52789,Q9NS69,Q8NHH9,Q8N1F7,P50897,O15258,Q5JTV8,Q9Y584,Q15006,Q9P2W9,O15400,Q86Y82,Q96CP7,Q8WWC4,O15498,Q9UII2,Q9NVH1,Q9Y512,O75844,O14737,P45880,Q12846,Q5JRA6,O43752,Q86XL3,P20700,Q9P0J0,Q00765,P08183,P33527,Q9BZG1,P33897,Q9H4A6,Q8N4V1,P02545,Q15629,Q15070,Q9NQC3,Q5XKP0,Q15392,Q96E52,Q08431,Q9H2C2,Q9HD42,Q13505,Q6NUK4,Q96A33,P62820,O60499,Q9Y5J9,O75955,P53350,O95295,O95249,Q9BTV4,O43681,O60313,Q14203,O60220,P12235,Q96JH7,Q9NPA0,Q969M3,Q9Y3E7,O14964,Q9BUR5,O94901,Q9H267,Q16891,P61916,P50570,Q9NZJ7,Q9Y255,Q01082,Q15363,P04083,Q14849,Q8N8Q8,Q9Y5J6,P07900,Q9BRK0,Q9P0I2,Q6UXV4,P57088,O15118,O95202,Q9H3K2,P50402,Q9NX63,Q12981,P30536,Q9BSR8,Q9NV96,Q9H6H4,Q96AA3,Q9UH99,O14653,O95721,Q53H12,Q16739,P46379,Q9Y5L4,P05141,Q9Y371,P16615,P49755,O43760,Q9NR31,Q8IWA4,Q13190,O00429,P51790,Q99758,Q06481 114 +Cation transport 0.5063586214850109 4.905424140064735 9.322566676650868e-07 0.0061126959509051 0.0006812724559155 171 Q9UDW1,P06756,O43707,P36543,Q9H2J7,P50570,Q8N4V1,Q9NUT2,Q9Y6M7,Q9NP58,O75027,P62258,P00846,Q02790,O76024,Q8TAD4,P05067,O00400,Q9UM00,P23634,Q9HC07,P05023,Q9BPX6,P46934,P56385,O14548,Q8IYU8,O75964,P98164,O43808,P00403,Q15043,P20020,Q9HD47,P27105,Q9H9B4,Q06787,Q96RD7,Q96QD8,Q96ES6,O95202,P06576,P05141,P62942,P02786,O15173,Q9HD20,Q99623,P16615,Q8N1S5,Q96PU5,Q9HC21,Q9NW15,Q8WWC4,Q13423,P13073,P21796,Q9UJZ1,P12235,O75844,Q9Y619,Q6P4Q7,Q04656,P20674,Q13586,P30825,Q9NWR8,P30536,O00429,Q70HW3,P51790,Q9NRA0,Q7KZN9,P24539 74 +Sphingolipid metabolic process 0.7892750470962158 4.788881812759471 1.677132148270033e-06 0.0109698944110359 0.0011030498139178 32 Q06136,Q96G23,Q9NZJ7,Q16880,P50897,Q8N5B7,P06280,P16278,Q9H2C2,Q9P035,P17900,Q53H12,O95470,P04062,Q13510,Q16739,P06865,P07602,P27544,P30153,Q99805,Q8NCC3,O15269 23 +Membrane lipid metabolic process 0.7296906466018425 4.6671077065006 3.054692222059785e-06 0.0198902672872099 0.0018264282494994 43 Q06136,Q96G23,Q9NZJ7,Q16880,P50897,Q8N5B7,P06280,Q9H490,P16278,Q9H2C2,Q9P035,P17900,Q53H12,O95470,P04062,Q13510,Q16739,O43292,P06865,P07602,P27544,P30153,Q99805,Q8NCC3,Q5H8A4,Q9NRA0,O15269 27 +Organophosphate ester transport 0.6959973067266648 4.249828621112497 2.139341344142842e-05 0.1312553021363625 0.0111876572274115 35 P33897,Q9Y255,O00400,Q8TB61,P12236,Q9H2D1,O43808,Q8WTV0,P05141,Q9HC21,P12235,Q6NUK1,Q08722,Q9BSK2,Q99758,Q9NV96,Q14108,P08183,P33527 19 +Inner mitochondrial membrane organization 0.7548137506054886 4.242408649603828 2.21133562348097e-05 0.1353592290934823 0.0111876572274115 25 Q16891,Q5XKP0,Q96E52,Q9Y5J6,Q13505,Q53H12,Q9Y584,Q9Y5J9,Q6UXV4,Q9Y5L4,O95202,Q9H3K2,Q9NX63,Q8WWC4,O60313,Q9NVH1,O60220,Q9P0J0,Q9BUR5 19 +Chemical homeostasis 0.4065186591966476 4.218795436804168 2.456109847570609e-05 0.1491677820024032 0.0111930264448927 200 P06756,O75880,P52789,P09601,O75787,O75027,P50897,P30519,Q9Y6C9,Q9HC07,Q8N511,Q9HD47,P22413,Q86YV9,P62942,Q7L0J3,Q96CP7,Q8WWC4,Q9UJZ1,Q12846,Q92544,Q15067,P33897,Q9Y6N1,P53985,Q9NP58,Q9NQC3,Q8TAD4,P51572,P05023,Q9BWH2,Q5BJF2,Q96A33,P04062,Q8WTV0,O75503,P02786,O95295,Q9HD20,Q16822,Q96PU5,Q9HCL2,Q8N5M9,Q96RR1,Q04656,O95563,Q13586,Q15904,Q8NE01,P62258,P42785,Q16891,P61916,Q9Y6M7,O76024,Q9UM00,P05067,P55011,O15260,O43819,Q8IYU8,Q8NF37,P05026,Q9H4M9,O15118,O95202,Q05086,Q6P4Q7,Q9Y3D6,P30536,Q93050,P23634,Q92859,Q9BPX6,Q9P035,Q16739,Q15043,P20020,P06576,P16615,Q9Y487,Q9NP80,Q9P0T7,Q9NWR8,P51790,Q99758,Q06481 87 +Membrane lipid biosynthetic process 0.7221824250778605 4.164022713362213 3.126889881510664e-05 0.1858891662783569 0.0124857107086923 29 Q9P035,P27544,Q99805,Q06136,Q96G23,O95470,Q53H12,P04062,Q13510,Q16739,Q5H8A4,O43292,Q16880,Q8N5B7,Q9NRA0,O15269,Q9H490 17 +Anion transmembrane transport 0.6696875899694198 4.156807078642431 3.227262916949414e-05 0.1912460160888874 0.0124857107086923 48 Q96NB2,Q9UJS0,Q9H936,P53985,Q9Y6M7,O15439,P55011,P51798,Q8TB61,Q00325,P98164,Q02978,P12236,Q9H2D1,O43808,Q9H9B4,Q9Y277,P05141,O75746,O75915,Q9HC21,Q9UBX3,P21796,Q9UHG3,Q9BQT8,P12235,Q9Y619,O60831,P45880,P51797,O95563,P30825,P51790,P04920,P08183,P33527 36 +Endoplasmic reticulum organization 0.6616834102809509 4.092832107387505 4.2613627329712855e-05 0.24442467403201 0.0155705459415293 47 P61026,Q12907,Q8N4V1,Q8NHH9,Q15629,Q15363,Q9NQC3,O95197,Q6NUK4,Q96A33,Q9BRK0,Q9P0I2,Q15006,P46379,Q9P2W9,O43681,Q12981,Q8N5M9,P49257,A0FGR8,Q5JRA6,Q96JH7,O00429,Q9NPA0,Q00765,Q9H6H4 26 +Ceramide metabolic process 0.787493791396401 4.07917431886848 4.519593831631141e-05 0.2571494539602191 0.0156449308582308 22 P27544,Q99805,P30153,Q96G23,Q8NCC3,P17900,Q53H12,O95470,P04062,Q13510,Q16739,Q16880,Q8N5B7,P06865,P06280,O15269 16 +Organic anion transport 0.6578583294795087 4.045840652130757 5.213568961059955e-05 0.2902946318084345 0.0159998294460033 51 Q9H2J7,Q9NZJ7,Q9UJS0,P53985,Q9Y6M7,P04083,O00400,O15439,Q8TB61,P98164,P12236,Q9H2D1,O43808,Q9H9B4,Q96QD8,P07602,P05141,Q7L0J3,O75746,Q9HC21,Q9UBX3,Q9NP80,Q9BQT8,P12235,Q6NUK1,Q9Y619,Q08722,O95563,P30825,P33527 30 +Establishment of protein localization to organelle 0.396936424691476 4.039701500380365 5.351927137176027e-05 0.2967238638099195 0.0159998294460033 199 Q9UHB9,Q15388,P61026,O60830,Q8N4H5,P49458,P52789,O75381,Q9NS69,P13473,Q8N1F7,P02545,P11233,Q99595,Q15629,Q15070,Q9BRG1,O15397,P51572,Q8N8Q8,Q7Z4Q2,Q9Y5J6,P52292,P46934,Q7Z3B4,Q53H12,Q9Y584,Q15005,P46379,Q9Y5J9,O14925,Q9HD47,Q9Y5L4,Q9H1Z9,O43615,Q53FT3,O95373,Q8NFH5,Q9Y371,O75312,Q99623,Q8WWC4,Q96RL7,P11279,Q9H300,P49257,Q9UII2,O60220,Q9Y512,O14737,Q10713,Q9Y3D6,P30536,Q9Y5M8,Q9P0J0,Q14108,Q92973,P40855,Q06481 59 +Protein insertion into membrane 0.6775277310003429 3.9574192667764407 7.576388181451676e-05 0.3924482536285843 0.0207624604455868 32 O14737,Q53H12,Q9NS69,Q96A33,Q8N4V1,Q9Y584,Q15006,Q15629,P46379,Q15070,Q9Y5J9,Q8WWC4,Q9NPA0,Q9Y5L4,Q9P0J0,Q8N8Q8,O60220,Q9Y5J6 18 +Mitochondrial membrane organization 0.6429660206275424 3.913452087005118 9.098596056489328e-05 0.4503325873596015 0.0231025664783292 52 Q16891,P52789,Q9NS69,Q15070,Q8N8Q8,Q5XKP0,Q96E52,Q9Y5J6,Q13505,Q53H12,Q9Y584,Q9Y5J9,Q6UXV4,Q9Y5L4,O95202,P05141,Q9H3K2,Q9NX63,Q8WWC4,O60313,Q8IWA4,Q9UII2,Q9NVH1,O60220,P12235,O14737,P45880,Q9P0J0,Q9BUR5 29 +Carboxylic acid transport 0.6409655055518559 3.912545361661947 9.13283759216288e-05 0.4515691942844737 0.0231025664783292 37 Q9H2J7,Q9NZJ7,Q9UJS0,Q9H936,P53985,P04083,O15439,P55011,Q02978,P98164,Q9H2D1,Q9H9B4,Q96QD8,P07602,Q7L0J3,O75746,O75915,Q9UBX3,Q9NP80,Q9BQT8,Q9Y619,O60831,O95563,P30825,P33527 25 +Localization within membrane 0.391844865493868 3.875145030999239 0.000106561213595 0.5038566819665569 0.0259575222894415 212 Q9UHB9,Q9BZG1,P61026,Q8N1B4,P43307,P49458,Q9H4A6,Q9NS69,O00264,Q8N4V1,P50570,Q9NZJ7,Q15629,P11233,Q13637,Q15070,O15258,Q01082,Q15363,Q9BTX1,Q9Y5L4,P23634,Q8N8Q8,Q9Y5J6,P07900,Q7Z3B4,Q9UPT5,Q53H12,Q96A33,Q9Y584,Q9BRK0,Q9P0I2,Q15006,Q07954,Q9Y5J9,P46379,O60725,Q9HD47,Q96A65,P27105,O15400,Q8N2H4,Q86YV9,P05026,O75955,P07602,O95429,Q9H4M9,Q99442,O15118,Q9UID3,Q9HD20,Q9Y371,P57105,Q9Y276,O43681,Q15643,Q8WWC4,O60220,Q9Y512,Q9H173,Q99805,O14737,Q12846,Q9Y3D6,O43752,Q92544,Q9NPA0,O00560,Q9HD45,Q9P0J0,Q15904,Q96L92,O14964,P40855,P35613 76 +Lytic vacuole organization 0.6734960288085864 3.8004228786909366 0.0001444493698734 0.6133023389440788 0.0322895672443662 29 Q9BZG1,O75787,P50897,Q6IAA8,Q9HC07,Q8N511,P04062,P54802,O75503,O14773,O95295,P10253,P11117,Q9P0T7,P42345,Q9Y3E7,P07686,Q14108,Q96ED9,Q12768,Q9P253 21 +Sphingolipid biosynthetic process 0.7766276561191618 3.797073189664278 0.0001464145706282 0.6182690104246175 0.0322895672443662 20 Q9P035,P27544,Q99805,Q06136,Q96G23,O95470,Q53H12,P04062,Q13510,Q16739,Q16880,Q8N5B7,O15269 13 +Carbohydrate derivative transport 0.7605263737024685 3.795604695512067 0.000147284022705 0.6204459850522448 0.0322895672443662 21 Q6NUK1,Q08722,P33897,L0R6Q1,Q96AA3,Q8TB61,Q9HC21,Q9NZJ7,P12236,Q8WTV0,O00400,P07602,P05141,P12235 14 +Mitochondrial transmembrane transport 0.6290549647798231 3.7820614440481815 0.0001555349562558 0.6404970758978944 0.0329984970095106 55 P23786,Q15388,O60830,Q99595,O75027,P00846,Q9BPX6,P56385,Q8IYU8,O75964,P12236,Q9H2D1,O14925,O43615,P06576,O95202,P05141,O75746,Q8WWC4,P50416,P21796,Q9BQT8,P12235,Q9Y619,Q9BSK2,Q9NWR8,P24539 27 +Organic acid transmembrane transport 0.6322700511604556 3.7361106949048426 0.0001868884235709 0.7074969059765824 0.0372474291462472 35 P23786,P33897,Q9H2J7,Q9UJS0,Q9H936,P53985,O14678,Q02978,P98164,Q9H2D1,Q9H9B4,Q96QD8,O75746,O75915,P50416,Q9UBX3,Q9BQT8,Q9Y619,O60831,O95563,P30825,P08183,P33527 23 +Cation transmembrane transport 0.5396127178634847 3.7167896449820224 0.0002017702994754 0.7347751060852983 0.0378720390952866 134 Q9UDW1,P06756,O43707,P36543,Q9H2J7,Q8N4V1,Q9Y6M7,O75027,P00846,Q8TAD4,P05067,O00400,P23634,Q9BPX6,Q9HC07,P46934,P56385,O14548,Q8IYU8,O75964,P00403,Q15043,P20020,Q9HD47,P27105,Q06787,Q96RD7,Q96ES6,O95202,P06576,P05141,P62942,Q9HD20,Q99623,P16615,Q8N1S5,Q96PU5,Q9HC21,Q9NW15,Q8WWC4,Q13423,P13073,P21796,P12235,Q9Y619,Q6P4Q7,Q13586,P30825,Q9NWR8,Q70HW3,P51790,Q9NRA0,Q7KZN9,P24539 54 +Mitochondrial respiratory chain complex assembly 0.6136698722403222 3.713298208372838 0.0002045755925805 0.739624723834984 0.0378720390952866 41 Q9Y2R0,O75880,Q86Y39,Q15070,O43676,Q8N8Q8,Q96E52,O95139,O43819,O95168,Q69YU5,Q96CU9,Q8N183,Q6DKK2,Q96I36,P03886,Q7L592,Q9Y6M9,P51970,Q9H061,O96000,Q9Y512,Q9BSK2,Q9P0J0 24 +Nucleotide transport 0.7785704266344892 3.5527309915211993 0.0003812541271532 0.918567963513947 0.0659870630075569 17 Q6NUK1,Q08722,P33897,Q9BSK2,Q8TB61,Q9HC21,P12236,Q9H2D1,O43808,O00400,P05141,P12235 12 +Inorganic ion transmembrane transport 0.5383318961922998 3.537704233220071 0.0004036219020948 0.9297122062364532 0.0680672115404596 128 Q9UDW1,P06756,O43707,P36543,Q9H2J7,Q8N4V1,Q9Y6M7,O75027,P00846,Q8TAD4,P23634,O00400,Q9BPX6,Q9HC07,P46934,P56385,O14548,Q8IYU8,O75964,P00403,Q15043,P20020,Q9HD47,P27105,Q06787,Q96RD7,Q96ES6,O95202,P06576,P05141,P62942,Q9HD20,Q99623,P16615,Q8N1S5,Q96PU5,Q8WWC4,Q13423,P13073,Q9UBX3,P21796,Q9UHG3,P12235,Q6P4Q7,Q13586,Q9NWR8,P51790,Q9NRA0,Q7KZN9,P51797,P24539 51 +Organic acid transport 0.5909064259409547 3.4563075744402547 0.0005476300522431 0.9727512990507244 0.0857562584191191 50 P23786,P33897,Q9H2J7,Q9UJS0,Q9H936,P53985,P04083,O14678,O15439,P55011,Q02978,P98164,O43808,Q9H2D1,Q9H9B4,Q96QD8,Q7L0J3,O75746,O75915,P50416,Q9UBX3,Q9NP80,Q9BQT8,Q9Y619,O60831,Q9Y3D6,Q6P4A7,P30825,O95563,P08183,P33527 31 +Protein transmembrane transport 0.6348583332630235 3.432469063456782 0.0005981121147651 0.9804535241036636 0.0914833343909358 27 Q15388,O75381,O60830,Q9NS69,Q9Y584,Q15629,Q99595,O14925,Q07820,O43615 10 +Anion transport 0.5876451120739472 3.4107332749074435 0.0006478843623856 0.9859131904087236 0.0946918989202257 79 Q9H2J7,Q9NZJ7,Q9UJS0,P53985,Q9Y6M7,P04083,Q9C0H2,O00400,O15439,Q86WC4,P55011,Q8TB61,P98164,O43808,Q9H2D1,P12236,Q15043,P22413,Q9H9B4,Q96QD8,P07602,Q9Y277,P05141,Q7L0J3,O75746,Q9HC21,O43681,Q9NW15,Q9UBX3,P21796,Q9NP80,Q9UHG3,Q9BQT8,P12235,Q08722,Q9Y619,Q6NUK1,P45880,P51797,O95563,P30825,P30536,P51790,P08183,P33527,Q96S66 46 +Nitrogen compound transport 0.3954730448285954 3.4038576059867864 0.0006644137960813 0.9873652190407683 0.0949967290614643 648 Q15154,O60830,Q8N4H5,P43307,P24390,O43707,Q9NS69,P49458,Q8N1F7,Q99595,P50897,O75027,O14678,Q96PU8,Q9BXS5,P46934,Q9Y584,Q15005,O43808,Q9H2D1,O14925,O60725,Q9HD47,Q9P2W9,O15400,Q86YV9,P07602,Q86Y82,Q53FT3,Q8NFH5,O15173,Q7L0J3,P57105,Q99623,Q8WWC4,P41208,O15498,P50416,Q14012,O43731,P49257,Q9UII2,Q9Y3A6,P10619,Q9Y512,Q8WTW3,O14737,Q9BSK2,Q12846,Q5JRA6,O43752,Q13438,Q92544,Q9Y5M8,O95070,Q9P0J0,P40616,Q14108,P08183,Q9UBV2,O15127,P33527,Q12768,Q8NFH4,Q96PC5,P33897,Q9BZG1,Q12907,Q9H2J7,P61026,Q9H4A6,Q05D32,P53985,Q15629,P02545,Q15070,Q9NP58,Q13637,Q9BRG1,Q96CS3,P61019,O00400,P51572,O15439,P52292,Q6I9Y2,Q8TB36,Q9HD42,Q5T9L3,Q9H0U4,Q8TB61,P98164,P62820,Q9BUN8,O60499,Q9Y5J9,Q07954,P82979,Q96A65,P27105,Q8N2H4,Q9H9B4,Q9C0E2,Q96QD8,O75955,Q9Y277,P02786,O95295,Q9HD20,Q16822,Q9Y2T2,O75746,O95249,O43681,Q96RL7,Q8N5M9,Q969Q5,P61020,Q07820,O60220,P12235,Q08722,Q9Y619,Q16850,Q9H173,Q9GZP9,Q86UP2,Q9Y282,O95563,Q99584,Q969M3,Q15904,Q96KC8,Q9Y3E7,Q92973,P40855,O14964,P62258,Q8TCT9,Q15388,Q9H267,Q8N1B4,L0R6Q1,Q8TEM1,P50570,Q9NZJ7,Q32P28,Q9UJS0,Q01082,Q15363,P04083,O15504,O15397,Q9Y3E0,Q8N8Q8,Q7Z4Q2,Q9Y5J6,P55011,P60604,O15260,P07900,Q9UPT5,A6NIH7,Q9BRK0,P12236,Q03518,P12270,P05026,Q86TM6,O95429,Q9H4M9,O43615,Q99442,Q9UID3,O96008,O75312,P50402,Q8N183,Q9Y276,Q9GZY8,Q8TBQ9,P49321,P61923,Q9H300,Q5JRX3,P35580,P22626,Q9Y3D6,P30825,P30536,Q96L92,Q9NV96,Q96ED9,Q9UHB9,O75381,Q8TD16,O14653,P13473,Q8WVM8,Q9Y3C0,Q9BTX1,O95721,Q96FV9,Q7Z3B4,Q53H12,P46379,Q9Y5L4,Q06787,P05141,O95373,Q9Y371,Q16836,P53365,Q9HC21,P49755,P04035,Q9NR31,Q9UP83,Q9P0T7,Q16543,Q13190,Q6NUK1,Q10713,O00429,O00560,P27824,Q06481 227 +Proton transmembrane transport 0.5714666678446968 3.288873153377157 0.0010058934624905 0.998665356296254 0.1350155367918482 48 Q9UDW1,O43707,P36543,P00846,Q8TAD4,O00400,P05023,P56385,O14548,O75964,P00403,Q96ES6,P06576,P05141,Q99623,Q13423,P13073,Q9UJZ1,P12235,Q04656,P51790,Q9NRA0,Q7KZN9,P24539 24 +Establishment of protein localization to mitochondrial membrane 0.7076237329112692 3.265638934850177 0.0010921741283949 0.999243762266958 0.1436645848490662 19 O14737,Q53H12,Q9NS69,Q9Y584,Q8WWC4,Q9Y5J9,Q15070,Q9P0J0,Q9Y5L4,Q8N8Q8,O60220,Q9Y5J6 12 +Process utilizing autophagic mechanism 0.3607725690777522 3.245924896160819 0.0011706971964848 0.999549064379127 0.1473966176153108 184 P36543,Q93050,P52789,P09601,P13473,Q9NZJ7,Q8WVM8,Q9BRG1,O95721,Q9BWH2,P46934,Q9NZ45,Q9HD42,Q9H0U4,Q9UPT5,P04062,P62820,Q96A65,Q86UE4,Q96KQ7,O15118,P07602,Q86Y82,P05141,Q9UID3,Q9Y371,O95295,P27544,P53365,Q99623,P16615,Q96RL7,O14681,Q969Q5,P21796,Q9H300,Q07820,Q9Y487,Q9UII2,P42345,Q16543,P10619,O75844,Q9Y6I9,P12235,Q96HY6,Q9Y3D6,Q8TBX8,P30536,O00429,Q9Y3E7,O14964,O15269,Q9NQ88 54 +Liposaccharide metabolic process 0.6910444874929018 3.2417987358703626 0.0011877787340142 0.9995970362243236 0.1473966176153108 20 Q99805,P17900,P04062,Q16739,Q5H8A4,O43292,Q16880,P06865,P06280,Q9H490,P16278 11 +Purine nucleotide transport 0.7641025021693911 3.2111619426285074 0.0013219941233888 0.9998334987310876 0.1552634883844367 14 Q6NUK1,Q08722,P33897,Q8TB61,P12236,O43808,O00400,P05141,P12235 9 +Ceramide biosynthetic process 0.7619592699264889 3.1988491257453555 0.0013797735633043 0.9998861964742723 0.1592065039623249 14 P27544,Q96G23,Q53H12,P04062,Q16739,Q13510,Q16880,Q8N5B7,O15269 9 +Mitochondrial transport 0.5569573023043873 3.1830515624148727 0.0014573165975602 0.9999317110149866 0.1624537502059916 93 P23786,Q15388,O60830,Q8N4H5,P52789,Q9NS69,Q99595,Q15070,P00846,Q14849,Q8N8Q8,Q9Y5J6,P56385,Q53H12,O75964,Q9Y584,Q9Y5J9,O14925,Q9Y5L4,O43615,P06576,P05141,Q9Y371,Q8WWC4,P50416,Q9UBX3,Q9UJZ1,Q9H300,P49257,Q9UII2,O60220,P12235,Q6NUK1,O14737,P45880,Q10713,Q9Y3D6,P30536,Q9P0J0,P24539 40 +Sterol metabolic process 0.551869058903155 3.1677556092241868 0.0015362059920429 0.9999593859053528 0.1641779416330699 40 Q9H2C2,Q16850,P16435,Q9BQE5,O75845,P04062,Q14534,P04035,Q15125,Q14849,Q8WTV0,Q14739,P05067,O15118,Q15800,Q15392 16 +Protein exit from endoplasmic reticulum 0.6008883667415429 3.1655931414319056 0.0015476710325756 0.9999623402026092 0.1641779416330699 27 Q8TCT9,O15260,Q9GZP9,Q13438,Q92544,Q9BUN8,Q9NR31,Q9NV96,Q9HD47,Q96CS3,Q86TM6,P49257,Q9UBV2,P51572 14 +Transition metal ion transport 0.7027834159136225 3.1571948424407483 0.0015929486836565 0.9999720523344916 0.1657384265152726 18 P02786,Q9HD20,O15173,Q04656,Q8N1S5,Q8N4V1,Q15043,Q9NP58,O75027,Q02790,Q9H9B4,Q8TAD4,Q9HC07 13 +Protein localization to endoplasmic reticulum 0.548335772737077 3.1535853146502975 0.0016127807962562 0.9999754751114502 0.1657384265152726 38 Q9UHB9,P61026,Q96HY6,P49458,P24390,Q5JRA6,Q13438,Q15005,Q9Y5M8,Q15629,P46379,O43292,O15258,O43731,Q9NQC3,P51572 16 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.5811482145159336 3.10273911468681 0.0019173858313432 0.999996703838098 0.1871783567228889 30 Q6NUQ1,Q96JB2,Q12907,Q8TD16,Q9Y282,Q9H4A6,P24390,Q96RQ1,Q969X5,Q8WVM8,P49755,Q12981,P61923,Q92538,O15258,Q9P2W9,O43731,P35606 18 +Protein localization to mitochondrion 0.5583421034497922 3.099993586767574 0.001935248328593 0.9999970698595896 0.1871783567228889 66 Q15388,O60830,Q8N4H5,P52789,Q9NS69,P11233,Q99595,Q15070,Q9Y6C9,Q8N8Q8,P51572,Q9Y5J6,Q8TB36,P07900,Q53H12,Q9Y584,Q9Y5J9,O14925,Q9Y5L4,O95429,O43615,O96008,Q9Y371,Q9Y276,Q9GZY8,Q8WWC4,Q9H300,Q5JRX3,P49257,Q9UII2,O60220,Q9Y512,O14737,Q10713,Q9Y3D6,P30536,O00429,Q9P0J0 38 +Protein targeting to mitochondrion 0.5501899802602335 3.0559639316175033 0.0022433824096268 0.999999615491964 0.2021430743421924 54 Q15388,O60830,Q8N4H5,Q9NS69,Q99595,P51572,Q9Y5J6,Q8TB36,P07900,Q53H12,Q9Y584,Q9Y5J9,O14925,Q9Y5L4,O95429,O43615,O96008,Q9Y371,Q9GZY8,Q9H300,Q5JRX3,P49257,Q9UII2,O60220,Q9Y512,O14737,Q10713,Q9Y3D6,P30536,Q9P0J0 30 +Vacuole organization 0.5474290600501596 2.999632687286679 0.0027030536061931 0.9999999814362368 0.2285814534149955 62 Q9BZG1,Q8WVM8,O75787,P50897,Q16706,Q9HC07,Q8N511,Q9H0U4,P62820,P54802,P04062,O14773,Q96KQ7,O75503,Q86Y82,Q9Y371,P53365,P16615,P10253,Q9P0T7,P42345,Q8TBX8,Q14108,Q96ED9,Q12768 25 +Membrane lipid catabolic process 0.7795401083071636 2.986536660441089 0.0028215700544933 0.9999999915042194 0.2285814534149955 12 O95470,P17900,P04062,Q13510,P50897,P06280 6 +Cellular monovalent inorganic cation homeostasis 0.5664393277800017 2.979662175207276 0.0028856643378882 0.9999999944332292 0.2285814534149955 30 Q93050,Q9Y6M7,O75787,P50897,Q9HC07,P55011,P05023,Q8N511,P05026,O75503,P06576,O95295,Q05086,Q96PU5,Q9Y487,Q9P0T7,Q92544,P51790,Q15904 19 +Tetrapyrrole metabolic process 0.6248517573195886 2.965725626871329 0.0030196975470613 0.999999997700554 0.2285814534149955 22 P22830,P09601,O00264,P30536,O75027,O14678,Q9P0S9,Q7KZN9,P30519,P33527,Q9UII2 11 +Cytochrome complex assembly 0.7476921841064932 2.95712770534325 0.0031051948132607 0.9999999986918352 0.2285814534149955 13 Q9Y2R0,O75880,Q9BSK2,O43819,Q6DKK2,Q69YU5,Q96I36,Q15070,Q7KZN9,P53701,Q8N8Q8 11 +Retrograde transport endosome to golgi 0.5306427191124777 2.9421231307190543 0.0032597028688774 0.99999999952802 0.2285814534149955 37 Q8N1B4,O75436,O15260,O60499,O75503,Q8IUD2,Q4J6C6,Q9UID3,O60271,O95249,Q9Y5X3,O60749,Q8NBN3,O15498,P51151,P14373,Q14203,P49257,Q13190,O43752,Q9UNH7,Q92538,P40616 23 +Protein insertion into mitochondrial inner membrane 0.8578611066340203 2.9340927912309644 0.0033452418373305 0.9999999997315988 0.2285814534149955 8 Q53H12,Q9Y584,Q9Y5J9,Q9P0J0,O60220,Q9Y5J6 6 +Mitochondrial fusion 0.6668235800417851 2.9238630564427366 0.003457168044312 0.9999999998717692 0.2285814534149955 18 P02786,Q8TB36,Q8NAN2,Q9Y3D6,O95140,Q9NX63,Q9GZY8,Q8N2A8,O60313,Q8IWA4,Q9UJZ1,Q9Y6C9,Q96E52,Q9H300 14 +Establishment of protein localization 0.3793292735828956 2.875952534068272 0.0040281028011748 0.9999999999970416 0.2285814534149955 589 Q15154,O60830,Q8N4H5,P43307,P24390,O43707,Q9NS69,P49458,P52789,Q8N1F7,P11233,Q99595,P50897,Q9BXS5,P46934,Q9Y584,Q15005,Q15006,O14925,O60725,Q9HD47,Q9P2W9,O15400,Q9H1Z9,Q86YV9,Q86Y82,Q53FT3,Q8NFH5,P57105,Q99623,Q8WWC4,P41208,O15498,P50416,Q14012,O43731,P49257,Q9UII2,Q9Y3A6,P10619,Q9Y512,Q8WTW3,O14737,Q12846,Q5JRA6,O43752,Q13438,Q92544,Q9Y5M8,O95070,Q9P0J0,P40616,Q14108,Q9UBV2,O15127,Q12768,Q8NFH4,Q96PC5,Q9BZG1,P61026,Q12907,Q9H4A6,Q05D32,Q8N4V1,P53985,Q15629,P02545,Q15070,Q13637,Q9BRG1,Q96CS3,P61019,P51572,P52292,Q8TB36,Q9HD42,Q5T9L3,Q9H0U4,Q96A33,P98164,P62820,Q15058,Q9BUN8,O60499,Q9Y5J9,Q07954,Q96A65,P27105,Q8N2H4,Q9C0E2,P53350,P02786,O95295,Q9HD20,Q16822,Q9Y2T2,O95249,O43681,Q96RL7,Q8N5M9,Q969Q5,P61020,Q07820,O60220,Q9H173,Q16850,Q9GZP9,Q86UP2,Q9Y282,O95563,Q9NPA0,Q99584,Q969M3,Q15904,Q96KC8,Q9Y3E7,Q92973,P40855,O14964,P62258,Q8TCT9,Q15388,Q9H267,Q8N1B4,Q8TEM1,P50570,Q32P28,Q01082,Q15363,P04083,O15504,O15397,Q9Y3E0,Q8N8Q8,Q7Z4Q2,Q9Y5J6,P55011,P60604,O15260,P07900,Q9UPT5,A6NIH7,Q9BRK0,Q9P0I2,Q03518,P12270,P05026,Q86TM6,O95429,O15118,O43615,Q9H4M9,Q99442,P78371,Q9UID3,O96008,O75312,P50402,Q8N183,Q9Y276,Q9GZY8,Q8TBQ9,P49321,P11279,Q9H300,Q9Y3D6,P30536,Q96L92,Q9NV96,Q96ED9,O96028,Q9UHB9,O75381,Q8TD16,O14653,P13473,Q8WVM8,Q9Y3C0,Q9BTX1,O95721,Q7Z3B4,Q53H12,P46379,Q9Y5L4,O95373,Q9Y371,Q16836,P53365,P49755,P04035,Q9NR31,Q9UP83,Q9P0T7,Q16543,Q13190,Q10713,O00429,O00560,P27824,Q06481 200 +Monovalent inorganic cation homeostasis 0.5335723526089468 2.8402670404578765 0.0045075782726498 0.9999999999998752 0.2285814534149955 34 Q93050,Q9Y6M7,O75787,P50897,Q9HC07,P55011,P05023,Q8N511,P05026,O75503,P06576,O95295,Q05086,Q96PU5,Q9Y487,Q9P0T7,Q92544,P51790,Q15904 19 +Vascular transport 0.6882991801715572 2.835349816514898 0.0045775531880039 0.9999999999999216 0.2285814534149955 15 P02786,P30825,P98164,P23634,P53985,Q07954,Q96QD8,P08183,P33527,O15439 10 +Intracellular protein transport 0.3701382254012472 2.8345864971686563 0.0045885034466546 0.999999999999927 0.2285814534149955 365 Q15154,O60830,Q8N4H5,P43307,P49458,Q9NS69,Q8N1F7,Q99595,Q9BXS5,P46934,Q9Y584,Q15005,O14925,O60725,Q9HD47,Q9P2W9,O15400,Q86Y82,Q53FT3,Q8NFH5,P57105,Q99623,Q8WWC4,Q14012,P49257,Q9UII2,Q9Y3A6,P10619,Q9Y512,O14737,Q12846,O43752,Q13438,Q92544,Q9Y5M8,Q9P0J0,P40616,Q14108,Q9UBV2,Q05D32,Q15629,P02545,Q15070,Q13637,Q9BRG1,Q96CS3,P51572,P52292,Q8TB36,Q5T9L3,Q9H0U4,P62820,Q9BUN8,O60499,Q9Y5J9,P27105,Q9C0E2,O95295,Q9Y2T2,O43681,Q96RL7,Q969Q5,P61020,O60220,Q9H173,Q9GZP9,Q9Y282,Q15904,Q92973,P40855,O14964,P62258,Q8TCT9,Q15388,Q9H267,Q15363,O15504,O15397,Q8N8Q8,Q7Z4Q2,Q9Y5J6,P60604,O15260,P07900,Q9BRK0,P12270,P05026,Q86TM6,O95429,Q9H4M9,O43615,Q99442,O96008,O75312,P50402,Q9Y276,Q9GZY8,Q9H300,Q9Y3D6,P30536,Q96L92,Q9NV96,Q9UHB9,O75381,P13473,Q8WVM8,Q7Z3B4,Q53H12,P46379,Q9Y5L4,O95373,Q9Y371,P53365,P49755,Q9NR31,Q16543,Q13190,Q10713,O00560,Q06481 120 +Nucleotide transmembrane transport 0.782346072558616 2.821832087100148 0.0047750171221516 0.9999999999999788 0.2285814534149955 11 Q9BSK2,Q8TB61,O43808,P12236,Q9H2D1,P05141,P12235 7 +Organelle fusion 0.5273262318114101 2.819333315379072 0.0048123517646241 0.9999999999999832 0.2285814534149955 57 Q9BZG1,O14653,Q8N2A8,O95721,Q9Y6C9,Q96E52,Q8TB36,O60499,O15400,Q86Y82,P02786,O95295,O95249,Q9NX63,Q12981,O60313,Q8IWA4,Q9UJZ1,Q9H300,Q13190,Q12846,Q9Y3D6,O43752,Q96JH7,Q969M3,Q9BSR8,Q9Y3E7,Q8NAN2 28 +Sulfur compound transport 0.7489665185192431 2.8192995371354104 0.0048128582565019 0.9999999999999836 0.2285814534149955 12 P33897,Q70HW3,Q9UBX3,P33527,O00400 5 +Calcium ion import 0.6732518262506784 2.8180984890720047 0.0048308988938245 0.9999999999999852 0.2285814534149955 16 O75844,P16615,Q9NWR8,Q8IYU8,Q9NRA0,P21796,P23634,Q9BPX6 8 +Regulation of ph 0.5631260620234873 2.806991405977177 0.00500065757872 0.9999999999999952 0.2297701140981408 25 Q8N511,Q93050,Q92544,Q9Y6M7,P51790,O75787,P50897,Q9P0T7,Q15904,Q9Y487,O75503,P06576,Q9HC07 13 +Regulation of cellular ph 0.5631260620234873 2.806991405977177 0.00500065757872 0.9999999999999952 0.2297701140981408 25 Q8N511,Q93050,Q92544,Q9Y6M7,P51790,O75787,P50897,Q9P0T7,Q15904,Q9Y487,O75503,P06576,Q9HC07 13 +Protein targeting 0.4771910971372964 2.806082277847345 0.0050147885707674 0.9999999999999956 0.2297701140981408 130 Q9UHB9,Q15388,O75381,O60830,Q8N4H5,P43307,P49458,Q9NS69,P13473,Q15629,Q99595,P51572,Q9Y5J6,Q8TB36,P46934,P07900,Q7Z3B4,Q53H12,Q9Y584,Q15005,P46379,Q9Y5J9,O14925,O60725,P27105,O95429,Q9Y5L4,Q99442,O43615,O96008,Q9Y371,Q9Y2T2,P57105,O43681,Q9GZY8,Q96RL7,Q9H300,P49257,Q9UII2,O60220,Q9Y512,Q9H173,Q16543,O14737,Q10713,Q9Y3D6,Q13438,P30536,Q9Y5M8,O00560,Q9P0J0,Q14108,O14964,P40855,P62258 55 +Nadh dehydrogenase complex assembly 0.5518726754212478 2.7944185229008816 0.0051993140807231 0.9999999999999988 0.2304345453596582 28 O95139,Q96CU9,O95168,Q86Y39,Q8N183,Q9Y276,P03886,Q7L592,Q15070,Q9P0J0,Q9Y6M9,O43676,P51970,Q9H061,O96000 15 +Glycosphingolipid metabolic process 0.8054877208341329 2.7768582212022044 0.0054887115228583 0.9999999999999998 0.2304345453596582 10 Q99805,P17900,P04062,Q16880,P06865,P06280,P16278 7 +Amino acid transport 0.6222336862315263 2.768643113756444 0.0056290257562816 1.0 0.2304345453596582 20 Q96NB2,Q7L0J3,Q15758,Q9Y619,O75746,Q9H2J7,O60831,Q6P4A7,O75915,P30825,Q9UJS0,Q9H936,P05556,Q9H9B4,P08195,Q96QD8,P55011 17 +Vitamin transport 0.8061606608443685 2.7543361753897377 0.0058811324854224 1.0 0.2304345453596582 9 Q9HC21,P04062,Q9H2D1,Q8WTV0,O14678,P33527,P38435 7 +Cristae formation 0.7997590199241378 2.747893844956347 0.0059979424907921 1.0 0.2304345453596582 10 Q16891,Q9NX63,Q6UXV4,Q96E52,Q9BUR5,Q5XKP0,O95202,Q9NVH1 8 +Golgi vesicle transport 0.4334976127497018 2.7344547264115504 0.006248368739897 1.0 0.2304345453596582 149 Q96PC5,Q9BZG1,P61026,Q12907,Q8N1B4,Q8TD16,P24390,Q9H4A6,Q96RQ1,Q969X5,Q8NHH9,O14653,Q8WVM8,O15258,Q15363,P61019,P51572,O15260,Q9H0U4,P62820,Q8TBA6,O60499,Q9HD47,Q9P2W9,Q8N2H4,Q9UID3,O95249,Q15643,Q96RL7,Q12981,P49755,O15498,Q9NR31,P11279,O43731,Q9UP83,P49257,Q9Y3A6,Q13190,Q8WTW3,Q5JRA6,O43752,Q9Y282,O95070,P40616,Q9BSR8,O15127 47 +Protein transmembrane import into intracellular organelle 0.6819393188738088 2.725888777111882 0.0064128603754001 1.0 0.2304345453596582 14 Q15388,O60830,Q99595,O14925,O43615 5 +Porphyrin containing compound metabolic process 0.6214560434325822 2.687486253625376 0.0071992065456929 1.0 0.2304345453596582 19 P22830,P09601,O00264,P30536,O75027,Q9P0S9,Q7KZN9,P30519,P33527,Q9UII2 10 +Inorganic anion transport 0.5204359443548809 2.684014011698967 0.007274405748781 1.0 0.2304345453596582 33 Q9Y6M7,Q9C0H2,O15439,Q86WC4,P55011,Q15043,P22413,Q9Y277,O43681,Q9NW15,Q9UBX3,P21796,Q9UHG3,P45880,P51797,P30536,P51790,P08183,P33527,Q96S66 20 +Dicarboxylic acid transport 0.6398228815272073 2.6830848425968012 0.0072946481779354 1.0 0.2304345453596582 17 O75746,Q02978,O75915,Q9H936,Q9UJS0,P98164,Q9H2D1,Q9UBX3,Q9BQT8,P55011 10 +Protein import into mitochondrial matrix 0.7863315483225661 2.6796134853284332 0.0073707213772544 1.0 0.2304345453596582 10 Q99595,Q15388,O14925,O60830 4 +Endoplasmic reticulum to golgi vesicle mediated transport 0.5168329452860483 2.6758434344406816 0.007454145810203 1.0 0.2304345453596582 73 Q96PC5,Q12907,P24390,O14653,Q96RQ1,Q969X5,Q8NHH9,Q8WVM8,Q15363,P61019,P51572,Q9H0U4,Q9HD47,Q9P2W9,O95249,Q15643,P49755,O15498,Q9NR31,O43731,P49257,Q9Y3A6,Q13190,Q9Y282,Q5JRA6,O95070,Q9BSR8 27 +Aminoglycan metabolic process 0.6294407572191466 2.6745356629115844 0.0074832816600727 1.0 0.2304345453596582 18 Q9NX62,Q8NCH0,P54802,O43505,P06865,Q7LGA3,P15586,P16278 8 +Glycoprotein biosynthetic process 0.5141612265417775 2.664072241350891 0.0077200981619693 1.0 0.2304345453596582 63 Q9H4A6,P46977,Q16706,Q9HC07,Q9H9S5,Q6ZXV5,Q9NQX7,O15118,Q8N4A0,Q86YN1,P15291,Q8NCH0,Q15643,O60476,Q9BT22,O43505,P26572,Q92542,Q99805,Q04656,Q10472,P04844,Q7LGA3,O94923,Q9Y287,Q96AA3 26 +Glycolipid biosynthetic process 0.7180254817361339 2.646636367155373 0.0081296719795427 1.0 0.2304585072621129 12 Q99805,Q8NBX0,Q16739,Q5H8A4,O43292,Q16880,Q9H490 7 +Neuromuscular process 0.5330402980470434 2.6350016626639317 0.008413687101711 1.0 0.2334886922698473 28 O75844,P17900,P10253,P04062,P05067,O14773 6 +Metal ion transport 0.4911180509137234 2.633038806154821 0.0084624677848328 1.0 0.2338556748775025 111 P06756,O43707,Q9H2J7,P50570,Q8N4V1,Q9NUT2,Q9Y6M7,Q9NP58,O75027,Q02790,O76024,Q8TAD4,Q9UM00,P23634,Q9BPX6,Q9HC07,P05023,P55011,P46934,Q8IYU8,P98164,Q15043,P20020,Q9HD47,Q9H9B4,P27105,Q06787,Q96RD7,Q96QD8,O95202,P62942,P02786,O15173,Q9HD20,P16615,Q8N1S5,Q96PU5,Q8WWC4,Q9UJZ1,P21796,O75844,Q6P4Q7,Q04656,Q13586,Q9NWR8,P30536,O00429,Q9NRA0,P62258 49 +Regulation of lysosomal lumen ph 0.7924607681268753 2.615688087771581 0.0089047861615321 1.0 0.2380763357089299 8 Q8N511,O75787,P50897,Q9P0T7,O75503,Q9HC07 6 +Cellular homeostasis 0.4061182933038618 2.6034592248390025 0.0092288244766332 1.0 0.2418246158677951 157 P06756,O75880,Q16891,Q93050,P52789,P09601,P13473,Q9NUT2,Q9Y6M7,O75787,O75027,P50897,Q9NP58,Q9NQC3,Q8TAD4,O76024,P51572,P05067,Q9UM00,Q9HC07,P05023,P55011,Q8N511,Q9BWH2,P23634,Q9BPX6,O43819,Q8IYU8,Q96A33,Q15043,P20020,P22413,P05026,O75503,O95202,P06576,P62942,P02786,O95295,Q7L0J3,Q9HD20,Q16822,Q05086,P16615,Q8N183,P10253,Q96PU5,Q8WWC4,Q8N5M9,Q96RR1,Q14203,Q9UJZ1,Q9Y487,Q07820,Q9P0T7,P14625,Q12846,Q04656,Q9Y3D6,O95563,Q13586,Q92544,Q9NWR8,P51790,Q9BS26,Q15904,P07686,P04920,P51797,P62258 70 +Intracellular protein transmembrane transport 0.5622707470101183 2.590090474292692 0.009595071055543 1.0 0.2425115951907727 23 Q15388,O60830,Q15629,Q99595,O14925,O43615 6 +Establishment of protein localization to membrane 0.4971477602435769 2.5787326740406984 0.009916349319609 1.0 0.2441493777716316 100 Q9UHB9,Q9BZG1,P61026,P43307,P49458,Q9H4A6,Q9NS69,Q8N4V1,Q15629,Q15070,Q01082,Q8N8Q8,Q9Y5J6,P07900,Q53H12,Q96A33,Q9Y584,Q9BRK0,Q9P0I2,Q15006,P46379,Q9Y5J9,O60725,P05026,P27105,Q8N2H4,Q9Y5L4,O15118,Q99442,Q9HD20,Q9Y276,O43681,Q8WWC4,O60220,Q9Y512,Q9H173,O14737,Q9Y3D6,Q9NPA0,O00560,Q9P0J0,Q15904,P40855 43 +Sodium ion transport 0.5343188030356424 2.5703907873685945 0.010158385108528 1.0 0.2465376341652735 25 P46934,O43707,Q9H2J7,Q6P4Q7,P50570,Q96PU5,Q9Y6M7,P55011,Q96QD8,P05026,Q9HD47,P27105,P23634,P05023 14 +Mitochondrial calcium ion homeostasis 0.6798112231285547 2.5637454923653755 0.0103549443521577 1.0 0.2503840772211093 13 Q16891,Q9Y3D6,Q8IYU8,Q9NWR8,Q8WWC4,Q9BPX6,O95202 7 +Organelle membrane fusion 0.4890316538082253 2.5488294716369015 0.0108085137293028 1.0 0.2544923551035352 37 O95295,Q9BZG1,Q12846,O95249,O43752,O14653,Q96JH7,Q12981,O60499,Q969M3,Q9BSR8,Q9Y3E7,Q8IWA4,O15400,O95721,Q86Y82,Q13190 17 +Golgi organization 0.503595461115386 2.542452097938156 0.0110077688619876 1.0 0.2544923551035352 68 Q12907,Q9H4A6,P50570,Q8NHH9,Q14789,Q15363,P61019,O15260,P62820,Q8TBA6,Q7Z3D4,Q9P2W9,Q53FT3,Q9UID3,P48729,Q15643,P49755,Q9BTU6,Q9UP83,P49257,Q9Y3A6,Q7RTS9,Q13190,Q8WTW3,O43752,Q96JH7,Q969M3,P40616,Q9BSR8 29 +Amino acid transmembrane transport 0.6296603500031378 2.5381233574896593 0.011144869319581 1.0 0.2544923551035352 16 Q9Y619,O60831,Q96NB2,Q15758,O75746,Q9H2J7,P30825,O75915,Q9UJS0,Q9H936,P05556,Q9H9B4,P08195,Q96QD8 14 +Endoplasmic reticulum tubular network organization 0.6985107885236768 2.5359285469038997 0.0112149614430079 1.0 0.2544923551035352 12 O95197,Q6NUK4,Q9BRK0,Q8NHH9,Q9NQC3,Q9H6H4 6 +Homologous chromosome segregation 0.6983072175315129 2.5347662212683733 0.0112522390914358 1.0 0.2544923551035352 12 Q92791,P46379,Q9BTX1,Q96KQ7,O94901,P53350 6 +Sodium ion transmembrane transport 0.5785061848737348 2.534408296778756 0.0112637404415625 1.0 0.2544923551035352 21 P46934,O43707,Q9H2J7,Q6P4Q7,P50570,Q96PU5,P05023,Q9Y6M7,P05026,Q9HD47,P27105,P23634,P55011 13 +Regulation of membrane lipid distribution 0.7569977763956152 2.528519159159948 0.0114544834489973 1.0 0.2544923551035352 10 Q9H2C2,Q96CP7,Q9Y255,Q99758,Q9NV96,P33527,Q96AA3 7 +Antigen processing and presentation 0.5248008252898685 2.513704753199583 0.0119470404727635 1.0 0.2544923551035352 26 Q9BZG1,P61026,P04062,Q13637,P10321,Q03518,P04439,Q9NZ08,P01889,P61020,Q9UIQ6,Q99538 12 +Glycoprotein metabolic process 0.5013074934986269 2.5130058653227385 0.0119707344673853 1.0 0.2544923551035352 72 Q9H3H5,Q9H4A6,Q10471,P04843,P46977,Q16706,Q9HC07,Q9H9S5,Q9H0U4,P62820,Q86TM6,Q6ZXV5,Q9NQX7,O15118,Q8N4A0,Q86YN1,P15291,Q9NX62,O00754,Q8NCH0,Q15643,O60476,Q9BT22,O43505,P26572,P14314,Q92542,Q99805,Q04656,Q10472,P04844,Q9BS26,Q7LGA3,O94923,Q9Y287,Q96AA3 36 +Lipid metabolic process 0.346601955175477 2.5085573621314565 0.0121225283889747 1.0 0.2544923551035352 308 Q9BQE5,Q8N2A8,P50897,O14678,Q8NBN7,Q9H490,Q96PU8,P37268,P51648,P17900,Q8NBX0,Q13510,O43808,Q9HB40,P21953,Q16134,O14773,Q8NBJ4,P07602,Q86YN1,Q99538,P15291,Q99623,Q92604,P50416,Q9UG56,Q9UJZ1,Q15800,O75844,P46108,O14735,Q15067,Q8NHP8,Q2T9J0,Q9UBV2,Q9NUQ2,Q9H6K4,A1L0T0,P23786,P33897,P54619,Q96G23,P53985,Q16880,Q9NZ01,Q9HBU6,Q15392,Q96E52,P16278,P05023,Q9H2C2,O95470,Q92643,P98164,P04062,P49327,Q07954,P07099,Q8WTV0,Q9UKU0,Q16822,Q9NX62,Q9NTJ5,P21964,Q9HCL2,Q16850,Q8NCC3,Q14739,Q06136,Q9NZJ7,Q9NZC3,Q14849,P05067,P06280,P38435,Q9NPH0,Q8NF37,Q14534,Q15118,O43292,P06865,O15118,P27544,P30153,Q15125,Q9BT22,Q9H6V9,Q96N66,Q99805,P16435,P30536,Q5H8A4,Q8NCG7,O15269,Q96AA3,Q9H7Z7,Q8N5B7,Q9P035,Q53H12,Q16739,Q6UX07,P06576,Q16836,O75845,Q8N4Q0,P04035,Q9BTU6,Q9NP80,P42345,Q10713,Q53GQ0,Q8TBX8,Q9BY49,Q99758,Q9NRA0,Q06481 116 +Ceramide catabolic process 0.8140537445907278 2.5051816400549067 0.0122388522652798 1.0 0.2544923551035352 7 P06280,P04062,Q13510,P17900 4 +Plasma membrane organization 0.5079526304901407 2.504071178286482 0.0122773332189463 1.0 0.2544923551035352 31 Q9H2C2,Q9Y371,P33897,Q9HD42,Q96CP7,P16615,Q12846,Q8WUX9,P50570,Q9UNF0,Q9UQB8,Q16739,Q9UQN3,Q01082,Q9Y3E7,O75955,Q8N3R9 17 +Divalent inorganic cation homeostasis 0.4972847826109521 2.5032808820189447 0.0123047846925534 1.0 0.2544923551035352 60 Q16891,P06756,O76024,P05067,P23634,Q8TAD4,Q9BPX6,Q9HC07,Q8IYU8,Q96A33,Q15043,P20020,O95202,P62942,Q9HD20,Q7L0J3,P16615,Q8WWC4,Q6P4Q7,Q9Y3D6,Q9NWR8,Q13586,Q8NE01 23 +Ion homeostasis 0.4621514686999606 2.480502164920524 0.013119746708017 1.0 0.260202025073193 124 P06756,O75880,P33897,Q16891,Q9Y6N1,Q93050,P09601,Q9Y6M7,O75787,O75027,P50897,Q9NP58,O76024,P30519,Q8TAD4,P51572,P05067,Q9UM00,Q9HC07,P05023,P55011,Q8N511,P23634,Q92859,Q9BPX6,O43819,Q8IYU8,Q96A33,Q15043,P20020,Q9HD47,P22413,P05026,O75503,O95202,P06576,P62942,P02786,O95295,Q7L0J3,Q9HD20,P16615,Q96PU5,Q8WWC4,Q9UJZ1,Q9Y487,Q9P0T7,Q6P4Q7,Q04656,Q9Y3D6,Q13586,Q9NWR8,Q92544,P30536,P51790,Q15904,Q8NE01,P62258 58 +Secondary alcohol metabolic process 0.4828295410018718 2.47972337643931 0.0131484344115562 1.0 0.260202025073193 43 Q9H2C2,Q16850,P16435,Q9BQE5,O75845,P04062,Q14534,Q15125,Q14849,Q8WTV0,Q14739,P05067,O15118,Q15800,Q15392 15 +Cellular lipid metabolic process 0.3291772535234007 2.476742463260104 0.0132587534278973 1.0 0.2603252698366574 232 P50897,O14678,Q8NBN7,Q9H490,Q96PU8,P37268,P51648,Q8NBX0,P17900,O43808,Q13510,Q9HB40,Q16134,P07602,Q86YN1,Q99623,Q92604,P50416,Q9UG56,Q9UJZ1,Q15800,O75844,O14735,Q15067,Q8NHP8,Q2T9J0,Q9UBV2,Q9NUQ2,A1L0T0,P23786,P54619,P33897,Q96G23,Q9NZ01,Q16880,Q9HBU6,P16278,Q9H2C2,Q92643,O95470,P98164,P04062,P49327,Q07954,P07099,Q8WTV0,Q9UKU0,Q16822,Q9NX62,Q9HCL2,Q8NCC3,Q06136,Q9NZJ7,Q9NZC3,P06280,Q9NPH0,Q8NF37,Q15118,O43292,P06865,P27544,P30153,Q9BT22,Q96N66,Q99805,P16435,Q5H8A4,Q8NCG7,O15269,Q96AA3,Q9H7Z7,Q8N5B7,Q9P035,Q53H12,Q16739,Q6UX07,Q16836,Q8N4Q0,P04035,Q9BTU6,Q9NP80,Q10713,Q53GQ0,Q8TBX8,Q9BY49,Q99758,Q9NRA0,Q06481 88 +Respiratory chain complex iv assembly 0.7641909065235755 2.4742391209407457 0.0133520296014975 1.0 0.2603252698366574 8 Q9Y2R0,O75880,O43819,Q96I36,Q15070,Q7KZN9,Q8N8Q8 7 +Diol biosynthetic process 0.7506110342547531 2.472305069939807 0.0134244902809395 1.0 0.2603252698366574 9 P00374,O15269,P04062,Q13510 4 +Diol metabolic process 0.7506110342547531 2.472305069939807 0.0134244902809395 1.0 0.2603252698366574 9 P00374,O15269,P04062,Q13510 4 +Regulation of dna templated transcription in response to stress 0.6295241660432743 2.466212494843678 0.0136550300024429 1.0 0.2625506079974557 15 P09601,P46934,Q15418 3 +Homologous chromosome pairing at meiosis 0.7489875486668786 2.463920972512335 0.0137426408137024 1.0 0.2625506079974557 9 Q92791,P46379,Q9BTX1,Q96KQ7,O94901 5 +Protein catabolic process in the vacuole 0.7487563972230755 2.4627265871762005 0.0137885017592518 1.0 0.2625506079974557 9 Q8N511,P98164,P13473,P04062,Q96RL7,O14773 6 +Lysosomal protein catabolic process 0.7487563972230755 2.4627265871762005 0.0137885017592518 1.0 0.2625506079974557 9 Q8N511,P98164,P13473,P04062,Q96RL7,O14773 6 +Vesicle mediated transport 0.3586054986774669 2.461752265953059 0.0138260129158456 1.0 0.2625506079974557 412 Q96D71,P06756,P24390,P09601,Q8NHH9,P11233,P50897,O15258,Q9BXS5,O95197,P46934,O15020,P55899,Q9HD47,Q9P2W9,P22413,O15400,Q86Y82,Q7L0J3,P57105,Q5VW38,Q8NBN3,O15498,O43731,P49257,Q9Y3A6,Q8WTW3,Q12846,Q5JRA6,O43752,Q92544,Q9BRK5,O95070,P40616,Q14108,O15127,O95772,Q96PC5,Q9BZG1,P61026,Q12907,Q9H4A6,Q969X5,Q13637,Q9BRG1,P61019,P51572,O15439,Q08431,Q9HD42,Q9H0U4,P98164,P62820,Q07954,O60499,Q96A65,Q8WTV0,Q8N2H4,O75503,O75955,P02786,O95295,Q9NX40,Q9Y2T2,O95249,Q96PU5,Q96RL7,Q92905,Q8N5M9,P11717,Q14203,P61020,A0FGR8,Q08722,Q9Y282,Q99584,Q969M3,P78537,Q15904,Q9Y3E7,O14964,Q9H267,Q8N1B4,Q5KU26,Q96RQ1,P50570,Q01082,Q15363,Q14849,P04083,P05067,O15260,Q9UPT5,O15118,Q9UID3,Q12981,P11279,Q7Z6M1,Q9BSR8,Q96L92,O95159,Q96ED9,Q08380,Q8TD16,O14653,Q8WVM8,Q9Y3C0,O95721,Q8TBA6,Q06787,Q8IZ07,P16615,Q15643,P49755,O43760,Q9NR31,Q9UP83,Q13190,O00429,O00560,P27824,P51790,Q9NRA0,Q06481 124 +Vitamin transmembrane transport 0.8047008691920711 2.460737714412266 0.0138651686694819 1.0 0.2625506079974557 7 Q9HC21,P04062,Q9H2D1,Q8WTV0,P38435 5 +Lipoprotein metabolic process 0.5184760189261403 2.4600637248065187 0.0138912348206241 1.0 0.2625506079974557 26 P06756,Q9BQE5,Q92643,P04062,Q16739,Q5H8A4,O43292,P50897,Q9H490 9 +Endoplasmic reticulum membrane organization 0.7482373941558927 2.460044240973954 0.0138919889893742 1.0 0.2625506079974557 9 Q8NHH9,Q12981,Q15363,Q00765,Q9P2W9,Q9NQC3 6 +Positive regulation of macroautophagy 0.5565626948457577 2.4538061316647077 0.0141353165564181 1.0 0.2656227914044643 22 Q9Y371,P27544,P09601,P21796,O15269,P05141,P12235 7 +Protein insertion into er membrane 0.6369726247180544 2.4482589223172395 0.0143548457235567 1.0 0.2668348630564565 14 Q96A33,O43681,Q8N4V1,Q9NPA0,Q15006,P46379,Q15629 7 +Intracellular transport 0.3601765305007124 2.4457497454526074 0.0144551295957902 1.0 0.2668348630564565 619 Q96D71,Q15154,O60830,Q8N4H5,P43307,P24390,O43707,Q9NS69,P49458,P52789,Q8NHH9,Q8N1F7,Q99595,P00846,O14678,Q9BXS5,P46934,Q5SNT2,O75964,Q9Y584,Q15005,O14925,O60725,Q9HD47,Q9P2W9,O15400,P07602,Q86Y82,Q53FT3,Q8NFH5,P57105,Q99623,Q8NBN3,Q8WWC4,P23246,O15498,P50416,Q14012,Q9UBX3,O43731,Q9UJZ1,P49257,Q9UII2,Q9Y3A6,P10619,O75844,Q9Y512,O14737,P45880,Q12846,Q5JRA6,O43752,Q13438,Q92544,Q9Y5M8,O95070,Q9P0J0,P40616,Q00765,Q14108,Q9UBV2,P24539,Q8WXH0,P23786,Q96PC5,P33897,P54619,P61026,Q12907,Q05D32,Q969X5,Q15629,P02545,Q15070,Q13637,Q9BRG1,Q96CS3,P61019,P51572,P52292,Q9H2C2,Q6I9Y2,Q8TB36,Q9HD42,Q5T9L3,Q9H0U4,P62820,Q9BUN8,O60499,Q9Y5J9,Q07954,P82979,P27105,Q8N2H4,Q9C0E2,O75503,O95295,Q9Y2T2,O95249,O43681,Q96RL7,O60313,P11717,Q14203,Q969Q5,P61020,O60220,P12235,Q9H173,Q9Y366,Q9GZP9,Q9Y282,Q969M3,P78537,Q15904,Q9Y3E7,Q92973,P40855,O14964,Q9UBK9,O94901,P62258,Q8TCT9,Q15388,Q9H267,Q8N1B4,P61916,Q96RQ1,Q9NZJ7,Q15363,Q14849,O15397,P05067,Q8N8Q8,Q7Z4Q2,Q9Y5J6,P07196,O15260,Q9BRK0,Q03518,Q86TM6,O15118,O43615,Q9UID3,O75312,P50402,P11279,Q9H300,Q9Y3D6,P30536,Q9BSR8,Q96L92,Q9NV96,Q96ED9,Q9UHB9,O75381,Q8TD16,Q9UH99,O14653,P13473,Q8WVM8,Q96FV9,Q7Z3B4,P56385,Q53H12,P46379,Q9Y5L4,P06576,P05141,O95373,Q9Y371,P53365,P16615,Q15643,P49755,Q9NR31,Q16543,Q13190,Q6NUK1,Q10713,O00560,Q06481 182 +Regulation of mitochondrion organization 0.4875258619595872 2.4369784384231292 0.014810562445553 1.0 0.2683445432628158 54 Q9H4A6,Q8N2A8,P02545,P11233,Q9Y255,Q9NUQ9,Q9Y6C9,Q96E52,Q96A26,P05141,Q9H3K2,P27544,O60313,Q9UG56,P21796,Q9H300,Q9UII2,P12235,O14737,Q9Y3D6,P30536,O00429,Q9NQ88 23 +Phosphatidylglycerol metabolic process 0.6349664549142365 2.435666801039889 0.0148643696082548 1.0 0.2685795574546493 14 Q8NCC3,Q99623,Q92604,Q9HCL2,Q8NF37,Q99758,Q9UJZ1,Q9NP80 8 +Calcium ion transmembrane transport 0.4769250552786899 2.4111542273122075 0.015902122379469 1.0 0.2731061891249497 44 P06756,P16615,Q8IYU8,Q9NWR8,Q13586,Q8WWC4,P20020,Q06787,Q96RD7,O95202,P23634,P21796,Q9BPX6,Q9HC07,P62942 15 +Glycosylation 0.4849293684382147 2.410520514542912 0.0159297754319731 1.0 0.2731061891249497 54 P46977,Q16706,Q9HC07,Q9H9S5,P04062,Q6ZXV5,O15118,O75503,Q8N4A0,Q86YN1,P15291,Q15643,O60476,Q9BT22,O43505,Q9UP83,P26572,Q8WTW3,Q10472,P04844,Q96AA3 21 +Plasma lipoprotein particle clearance 0.653803901720809 2.4081769110184257 0.0160324099314721 1.0 0.2731061891249497 13 P61978,P09601,Q6PIU2,Q8WTV0,Q9Y2B0,Q9H4M9 6 +Regulation of vacuole organization 0.675774140043172 2.405150995865463 0.0161657847885132 1.0 0.2731061891249497 12 Q9Y371,Q9H0U4,Q8TBX8,Q8WVM8,Q14108 5 +Regulation of protein exit from endoplasmic reticulum 0.7328947257282603 2.402362000166505 0.0162895794689776 1.0 0.2731061891249497 10 Q9GZP9,Q13438,Q92544,Q9NR31,Q9NV96,P51572 6 +Bone morphogenesis 0.7353252195757523 2.393043309053471 0.0167092686027514 1.0 0.2731061891249497 9 O75844,P16435,Q9NX62,Q92896 4 +Neuromuscular process controlling balance 0.6511569093225114 2.392189700617299 0.0167481833974274 1.0 0.2731061891249497 13 P10253,P05067,O14773,P17900 4 +Cellular ion homeostasis 0.4798201273819071 2.384682612281296 0.0170938618525637 1.0 0.2731061891249497 101 P06756,O75880,Q16891,Q93050,P09601,Q9Y6M7,O75787,O75027,P50897,Q9NP58,O76024,Q8TAD4,P05067,P51572,Q9UM00,P23634,Q9HC07,P05023,P55011,Q8N511,Q9BPX6,O43819,Q8IYU8,Q96A33,Q15043,P20020,P22413,P05026,O75503,O95202,P06576,P62942,P02786,O95295,Q7L0J3,Q9HD20,Q05086,P16615,Q96PU5,Q8WWC4,Q9UJZ1,Q9Y487,Q9P0T7,Q04656,Q9Y3D6,Q13586,Q9NWR8,Q92544,P51790,Q15904,P07686,P04920,P62258 53 +Sterol biosynthetic process 0.5242251041387929 2.382725316996397 0.0171850118015752 1.0 0.2731061891249497 24 Q9H2C2,Q16850,P16435,O75845,Q14534,P04035,Q15125,Q14739,Q15800,Q15392 10 +Modified amino acid transport 0.7877317641303931 2.379514309900743 0.017335469921778 1.0 0.2731061891249497 7 P33527,P98164,O15439,Q9H2D1 4 +Negative regulation of transmembrane transport 0.5333928656701051 2.361681806846881 0.0181922492266695 1.0 0.2737401131250168 23 P46934,Q04656,Q96PU5,P22413,Q06787,P21796,Q06481,P62942 8 +Purine containing compound transmembrane transport 0.7250511502830086 2.36091480979459 0.0182299178270879 1.0 0.2737401131250168 10 Q8TB61,O43808,P12236,P05141,P12235 5 +Atp synthesis coupled electron transport 0.4687070815361738 2.3593863905892767 0.0183051849139317 1.0 0.2738810796002316 41 O95139,Q9H3K2,Q9UDW1,O75208,P03886,O14949,P00403,P13073,Q7KZN9,O43676,O96000 11 +Cartilage development 0.5749189238992694 2.358997908774618 0.0183243590297708 1.0 0.2738810796002316 19 O75844,P16435,Q92896,Q9NX62,Q96HY6,Q15043,Q8N5W9 7 +Phospholipid transport 0.5834826065752445 2.3581911840157668 0.0183642323405355 1.0 0.2738810796002316 18 Q9Y255,Q99758,Q9NV96,Q8WTV0,P08183,Q14108,P33527 7 +Protein o linked glycosylation 0.601454892079206 2.352162487683235 0.0186646196394364 1.0 0.2756760615993766 16 Q10472,O43505,Q8N4A0,Q6ZXV5 4 +Amide transport 0.4681560862741494 2.3454215681157207 0.0190055767974133 1.0 0.2762274296071136 37 P33897,Q9NZJ7,P53985,P04083,O00400,O15439,P98164,P62820,Q9H2D1,Q03518,P07602,Q16822,Q16836,Q8N5M9,P50416,Q12846,O95563,P08183,P33527 19 +Atp transport 0.8441998306519902 2.343429735927691 0.0191073608831668 1.0 0.2762274296071136 6 Q6NUK1,Q08722,P12236,P05141,P12235 5 +Membrane fusion 0.4736744864035625 2.341834797548989 0.0191892066459899 1.0 0.2762274296071136 48 Q9BZG1,Q9H267,O14653,O95721,O60499,Q9P2W9,O15400,Q86Y82,O95295,O95249,Q12981,O15498,Q8IWA4,Q13190,Q12846,O43752,Q96JH7,O00429,Q969M3,Q9BSR8,Q9Y3E7 21 +Endoplasmic reticulum calcium ion homeostasis 0.737120414542397 2.3365826314517717 0.0194608964374036 1.0 0.2762274296071136 8 P16615,Q9Y3D6,Q96A33,O76024,P05067,P51572 6 +Erad pathway 0.4674509198118255 2.3259147470326593 0.0200230991599561 1.0 0.2762274296071136 43 Q8TCT9,P60604,Q5VYK3,Q9GZP9,Q13438,Q96A33,Q9BUN8,P46379,P27824,Q9UBV2,Q96CS3,Q86TM6,O76024,Q6NTF9,P51572,Q4ZIN3,Q9UBU6 17 +Regulation of leukocyte mediated cytotoxicity 0.734886421680123 2.325125468494298 0.0200652521728252 1.0 0.2762274296071136 8 P46108,P04439,P11279,Q9NUQ9,O15400 5 +Negative regulation of neuron apoptotic process 0.49999858756432 2.3243227160184454 0.0201082042122171 1.0 0.2762274296071136 27 P07196,Q01105,P09601,P04062,P50897,O76024 6 +Metal ion homeostasis 0.479592675209007 2.318154219161766 0.0204409411025874 1.0 0.2762274296071136 92 P06756,O75880,Q16891,Q9Y6N1,P09601,Q9NP58,O75027,O76024,Q8TAD4,P30519,P51572,P05067,Q9UM00,Q9HC07,P05023,P55011,Q8N511,P23634,Q92859,Q9BPX6,O43819,Q8IYU8,Q96A33,Q15043,P20020,O95202,P62942,P02786,Q7L0J3,Q9HD20,P16615,Q96PU5,Q8WWC4,Q9UJZ1,Q9Y487,Q6P4Q7,Q04656,Q9Y3D6,Q13586,Q9NWR8,Q15904,Q8NE01,P62258 43 +Mitochondrial electron transport cytochrome c to oxygen 0.7735395831700446 2.3109988966880803 0.0208329158359428 1.0 0.2781384002467085 7 O14548,P15954,P00403,P13073,Q7KZN9 5 +Iron ion transport 0.6571226358472474 2.296420346987653 0.0216518586900478 1.0 0.2830647109036748 12 P02786,O15173,Q04656,Q8N4V1,Q15043,Q9NP58,O75027,Q9H9B4 8 +Mannosylation 0.7705247793383148 2.2963757962860334 0.0216544036489434 1.0 0.2830647109036748 7 Q9BT22,O43505,Q6ZXV5 3 +Regulation of glycoprotein metabolic process 0.6566420303482242 2.293601306564169 0.0218134102815126 1.0 0.284092672121799 12 Q92542,Q99805,Q9H0U4,Q9NQX7,Q9Y287 5 +Cerebellar purkinje cell layer development 0.7120719805206805 2.291904647939545 0.0219111460044734 1.0 0.2848015953980665 10 O15020,P04062,P54802,O14949,Q15058,Q96D53 6 +Export across plasma membrane 0.7260373774942075 2.279597057014301 0.0226315976715012 1.0 0.2877770058265396 8 P20020,P08183,P33527,O15439,P05023,P62258 6 +Regulated exocytosis 0.4606268844024802 2.278170401655826 0.0227164270180424 1.0 0.2877770058265396 41 Q7L0J3,P61026,Q12846,P16615,P09601,P49755,O43760,Q9BRK5,Q99584,P11279,Q9NRA0,Q06787,O95721,O15439 14 +L amino acid transport 0.653661294882691 2.276098089148943 0.0228401394315727 1.0 0.2877770058265396 12 Q9Y619,O60831,Q15758,O75746,O75915,P30825,Q9UJS0,Q9H936,Q9H9B4,P08195,Q96QD8 11 +Mitochondrial electron transport ubiquinol to cytochrome c 0.8848716235970226 2.2746294420049455 0.022928168390208 1.0 0.288333773427148 5 Q9UDW1 1 +Lipid localization 0.4759862917232443 2.2669634771736464 0.0233924569258057 1.0 0.2904970113764685 90 P23786,P06756,Q9BQE5,P33897,Q9NZJ7,Q9Y255,O14678,Q14849,O15439,Q9H2C2,O15260,P17900,P04062,O43808,Q07954,Q14534,Q16739,P22413,Q8WTV0,O15118,P07602,Q86Y82,Q9UID3,Q9C0B1,P50416,Q9UJZ1,Q9H6V9,Q9NP80,O95674,Q9H2V7,Q9Y3D6,Q99720,P30536,Q99758,Q9NV96,Q14108,P08183,Q9BUR5,P33527,Q96AA3 40 +Low density lipoprotein particle clearance 0.6520559049344321 2.2666572097109987 0.0234111743128078 1.0 0.2904970113764685 12 P61978,P09601,Q8WTV0,Q9Y2B0,Q9H4M9 5 +Ensheathment of neurons 0.4847995498646649 2.2657824264229554 0.023464707877371 1.0 0.2904970113764685 30 Q92542,O15228,P33897,O75312,O75746,P17028,P53634,Q9Y4W6,Q15058,Q9BX67,Q9NR77,Q16880,P07686,P49770,P42345,Q96PU8,Q8N3R9 17 +Metal ion export 0.7231658078275669 2.264772862298412 0.0235266215709752 1.0 0.2904970113764685 8 Q04656,P20020,P23634,O95202,P05023,P62258 6 +Mitochondrial cytochrome c oxidase assembly 0.7639751552794802 2.26452450596457 0.0235418742684594 1.0 0.2904970113764685 7 Q9Y2R0,O75880,O43819,Q96I36,Q15070,Q8N8Q8 6 +Mitochondrial calcium ion transmembrane transport 0.706002739970996 2.259452594770225 0.0238552459433118 1.0 0.2921712338345668 10 Q8IYU8,Q9NWR8,Q8WWC4,P21796,Q9BPX6,O95202 6 +Oxidative phosphorylation 0.4754086800383915 2.2508515367437476 0.0243949421075204 1.0 0.2960249709246533 66 Q9UDW1,P33897,O14949,P00846,O43676,O95139,P56385,O14548,O75964,P00403,Q9H3K2,O75208,P03886,P13073,P14406,O96000,Q9BSK2,Q7KZN9,P24539 19 +Ubiquitin dependent erad pathway 0.4538944180814203 2.2444278141207277 0.0248048885959175 1.0 0.2977039275462588 38 P60604,Q5VYK3,Q9GZP9,Q13438,Q96A33,Q9BUN8,P46379,P27824,Q9UBV2,Q96CS3,Q86TM6,O76024,Q6NTF9,P51572,Q9UBU6 15 +Regulation of cell killing 0.7061672428329723 2.239847259076424 0.0251008405902881 1.0 0.3001604155678641 9 P46108,P04439,P11279,Q9NUQ9,O15400 5 +Regulation of release of cytochrome c from mitochondria 0.6473571867132424 2.238969603243755 0.0251578940228498 1.0 0.300296676929734 12 Q9H3K2,O14737,Q96A26,O00429,O60313,Q9Y255,Q9H300 7 +Autophagy of mitochondrion 0.4562101770991572 2.233509764667475 0.0255153471204743 1.0 0.3029141480349451 41 Q9BWH2,P27544,P53365,Q16543,Q99623,Q9Y3D6,P52789,P04062,P30536,O00429,P21796,Q9UII2,P05141,Q9H300,P12235 15 +Mucopolysaccharide metabolic process 0.6736629782154177 2.230513465138068 0.0257133745449236 1.0 0.3044767773627796 11 P16278,Q8NCH0,Q9NX62,O43505 4 +Amyloid precursor protein metabolic process 0.5464127012175457 2.217007421800479 0.0266225843678149 1.0 0.3099941152410826 20 Q92542,O95197,Q9NQC3,Q9NQX7,Q15392,Q9Y287,P62942 7 +Endochondral bone morphogenesis 0.7138468501293016 2.2164962673367476 0.0266575332380036 1.0 0.3099941152410826 8 O75844,P16435,Q9NX62 3 +Calcium ion transport 0.4696630799035946 2.211178506595259 0.0270234781602418 1.0 0.3129109434153358 61 P06756,O76024,P23634,Q9BPX6,Q9HC07,Q8IYU8,P20020,Q06787,Q96RD7,O95202,P62942,P16615,Q8WWC4,P21796,O75844,Q9NWR8,Q13586,P30536,O00429,Q9NRA0 20 +Inorganic anion transmembrane transport 0.6960152925267934 2.2057980251273603 0.0273981446447197 1.0 0.3150457561789516 10 P51797,Q02978,P51790,Q9UBX3,Q9UHG3,P55011,P51798 7 +Nuclear envelope organization 0.4716855741562093 2.2028792556529813 0.0276032600944455 1.0 0.3162833478069139 32 O75844,Q9HD42,P50402,Q9UH99,Q6NUK4,Q9BTV4,Q86XL3,Q8N1F7,P02545,P20700,Q9Y3E7,Q14203,Q5JTV8,Q9H6H4,P53350 15 +Transition metal ion homeostasis 0.4796290408509829 2.1924817835441077 0.0283447370288685 1.0 0.318064302711886 29 Q8N511,P02786,O75880,Q04656,P09601,Q15043,Q9NP58,O75027,Q15904,Q9Y487,P05067,P30519,Q92859,Q8TAD4 14 +Sphingoid metabolic process 0.8082514288021652 2.1817231443698466 0.0291299717296711 1.0 0.3193130401100784 6 Q13510,O15269,P04062,Q06136 4 +Respiratory electron transport chain 0.4626383990645898 2.1806999859137717 0.029205614094895 1.0 0.319464105717577 54 O95139,Q9H3K2,Q9UDW1,O75746,O75208,O14548,P04062,O14949,P00403,P03886,P13073,Q7KZN9,Q16134,O43676,O96000 15 +Protein localization to vacuole 0.4880089007235038 2.177296610774435 0.0294584439038281 1.0 0.319464105717577 25 Q9Y371,P46934,Q9Y2T2,P13473,Q96RL7,Q9BRG1,Q14108,Q9NQC3 8 +Pigmentation 0.521078760600401 2.176356684091841 0.0295286000581416 1.0 0.319464105717577 22 Q9BXS5,O95295,Q9H267,Q13561,Q04656,Q8TAA9,P62820,P78537,Q13637,Q9NP58,O75787,P22413,Q86YV9 13 +Maintenance of protein location in cell 0.4873349404590887 2.1714592559676964 0.0298964738466989 1.0 0.3213757558016231 25 P52789,P24390,Q9UH99,Q13438,P30536,Q96RL7,O43292,O15258,O43731 9 +Xenobiotic transport 0.8059409364383909 2.1712315714733905 0.0299136719495134 1.0 0.3213757558016231 6 Q99758,Q9NV96,P08183,P33527 4 +Alcohol biosynthetic process 0.4457090282806532 2.1615974227583727 0.0306492202937795 1.0 0.3235632774834484 38 Q9H2C2,Q16850,P16435,O75845,Q15800,P04062,Q13510,P04035,Q15125,Q14739,Q9NRA0,O15269,P00374,Q15392 14 +Cellular transition metal ion homeostasis 0.4975318335829032 2.1606670471826255 0.0307210681561453 1.0 0.3238020276650132 24 Q8N511,P02786,O75880,Q04656,P09601,Q15043,Q9NP58,O75027,Q15904,Q9Y487,P05067,Q8TAD4 12 +Lysosomal lumen acidification 0.8024273214789912 2.155254183913245 0.0311419489271114 1.0 0.3260253155247103 6 Q8N511,O75787,P50897,Q9P0T7,O75503 5 +Intracellular lipid transport 0.5620415411930506 2.1552504236055228 0.0311422430237673 1.0 0.3260253155247103 17 Q9H2C2,P23786,P33897,P50416,O14678,O15118 6 +Negative regulation of ion transmembrane transporter activity 0.659966825171286 2.1531373219543246 0.0313078878388635 1.0 0.3268444100257227 11 Q96PU5,P46934,P62942 3 +Tetrapyrrole catabolic process 0.9112615056153298 2.1439017987523425 0.0320407560511699 1.0 0.3303121746160142 4 P30519,P09601 2 +Membrane docking 0.4645006062315952 2.1354857480388127 0.0327213531140397 1.0 0.3336563402031622 32 P61026,Q12846,P16615,O43752,O60499,O15498,O15400,O95721,Q7Z6M1,Q86Y82,Q13190 11 +Negative regulation of cellular response to growth factor stimulus 0.5877200314359255 2.133988210247612 0.0328437459159645 1.0 0.3343859394571185 14 P46934,P98164,Q05D32,O14964,P23634,Q8N0X7 6 +Protein retention in er lumen 0.8512979683972788 2.131395012889911 0.0330566133892518 1.0 0.3349081576107309 5 P24390,Q13438,O43731,O43292 4 +Maintenance of protein localization in endoplasmic reticulum 0.8512979683972788 2.131395012889911 0.0330566133892518 1.0 0.3349081576107309 5 P24390,Q13438,O43731,O43292 4 +Negative regulation of leukocyte mediated immunity 0.7367437361972499 2.130883716513247 0.0330987231940056 1.0 0.3349081576107309 7 P46108,P04439,Q96FV9,P09601 4 +Reactive nitrogen species metabolic process 0.5584477403260566 2.1301286206843444 0.0331609960187753 1.0 0.3350228430345395 17 Q08722,O43169,P16435,P30536,P06280 5 +Negative regulation of autophagy 0.4793123119750347 2.1212317821537434 0.0339023019209667 1.0 0.341986870757973 26 O15118,P09601,P30536,Q8WVM8,Q07820,Q9NQ88,P42345,P10619 8 +Mitophagy 0.5498259561928042 2.1195223713626694 0.0340463451739885 1.0 0.3424850820291887 18 P27544,P53365,Q99623,P21796,P05141,Q16543,P12235 7 +Glycolipid catabolic process 0.7341685361381574 2.1181449804448853 0.0341627911219653 1.0 0.3424850820291887 7 P06280,P04062,P17900 3 +Maintenance of protein localization in organelle 0.5493467302453515 2.1160814916713617 0.0343378773259219 1.0 0.3426398009568834 18 P52789,Q13438,Q9UH99,P30536,P24390,O43292,O43731 7 +Protein localization to golgi apparatus 0.653250171854535 2.1149584562512156 0.0344334882368664 1.0 0.3426398009568834 11 Q8TD16,Q96RL7,P49755,P40616,Q8N2H4 5 +Phosphatidic acid metabolic process 0.6930318632417308 2.107738566350657 0.0350536093929148 1.0 0.3471767527688693 8 O15228,Q9NPH0,Q9HCL2,Q8NF37,Q9NUQ2 5 +Amyloid precursor protein biosynthetic process 0.8456912794922904 2.1072659246120424 0.0350945353086886 1.0 0.3471767527688693 5 Q9NQX7,Q9Y287 2 +Vesicle docking 0.5480213839311947 2.1065592383883476 0.0351558031540317 1.0 0.3471767527688693 18 Q12846,O43752,O60499,O15498,O15400,Q7Z6M1,Q86Y82,Q13190 8 +Positive regulation of mitochondrion organization 0.4774942644892396 2.105224601086234 0.0352717617694233 1.0 0.3477996659032946 26 P27544,O14737,Q96A26,Q9Y3D6,O00429,Q8N2A8,P11233,P21796,P05141,P12235 10 +Negative regulation of ion transmembrane transport 0.5641564504100508 2.10038666098137 0.0356948414512414 1.0 0.3493019766976282 16 Q96PU5,P46934,P62942,P21796 4 +Regulation of mitophagy 0.6908505944008918 2.096267845775894 0.0360584374112467 1.0 0.3493019766976282 8 P27544,P12235,P05141,P21796 4 +Membrane protein proteolysis 0.623240759470457 2.095561162234785 0.0361211375005257 1.0 0.3493019766976282 12 Q92542,Q16740,Q9NZ08,Q8TCT8,Q9H300,P38159 6 +Calcium import into the mitochondrion 0.7296023787283495 2.0955150873369033 0.0361252286947697 1.0 0.3493019766976282 7 Q8IYU8,Q9NWR8,Q9BPX6,P21796 4 +Cytosolic calcium ion transport 0.4783294159764123 2.0931425094750815 0.0363364349633312 1.0 0.3493019766976282 25 P16615,Q8IYU8,Q9NWR8,P20020,O95202,P21796,P23634,Q9BPX6,P62942 9 +Release of cytochrome c from mitochondria 0.5629993339908443 2.092469667591394 0.0363965223777256 1.0 0.3493019766976282 16 Q9H3K2,O14737,Q9Y3D6,Q96A26,O60313,Q9Y255,Q9H300 7 +Proton transporting two sector atpase complex assembly 0.7886609605851138 2.0923927229011623 0.0364033992322063 1.0 0.3493019766976282 6 Q8N511,Q15070,Q9P0T7,Q9BUB7 4 +Apoptotic mitochondrial changes 0.4525821569686933 2.0837989643073924 0.0371784575962197 1.0 0.3519157496680592 34 Q9H3K2,O14737,P45880,Q96A26,Q9Y3D6,P52789,O00429,O60313,Q9Y255,Q9H300,Q9UII2,P05141,P12235 13 +Negative regulation of mitochondrion organization 0.5367063822305446 2.0804502935001077 0.0374842503180186 1.0 0.3530213640755493 19 Q9H3K2,P30536,P02545,O60313,Q9Y255,Q96E52,Q9H300,Q9NQ88,P05141 9 +Positive regulation of cell killing 0.7247014698506963 2.0711658960402795 0.0383432954722227 1.0 0.3556175385516336 7 P04439,P11279,Q9NUQ9,O15400 4 +O glycan processing 0.8357474151279218 2.0643257514893216 0.0389868410038336 1.0 0.3569565161005172 5 O43505,Q8N4A0 2 +Cartilage development involved in endochondral bone morphogenesis 0.8353080923320768 2.0624243734644523 0.0391673507898284 1.0 0.3569565161005172 5 O75844,P16435 2 +Golgi ribbon formation 0.6844237387340432 2.062390061701384 0.0391706147300547 1.0 0.3569565161005172 8 O43752,Q15643,Q9Y3A6 3 +Sensory perception of light stimulus 0.5336684698786573 2.0579671642364725 0.0395932855313143 1.0 0.3585029718018505 19 Q9H6K4,P50897,O60313,O76024 4 +Endoplasmic reticulum to cytosol transport 0.5569963594650238 2.051296129233622 0.0402381172095385 1.0 0.3610451526427487 16 Q8TCT9,P60604,Q9GZP9,Q13438,Q9BUN8,Q86TM6,Q96CS3,Q9UBV2,P51572 9 +Synaptonemal complex organization 0.7199087194881963 2.0472939764839473 0.0406292289727812 1.0 0.3635625019782068 7 Q96KQ7,Q92791,P46379 3 +Regulation of blood pressure 0.4936506862347712 2.0383523028451926 0.0415147127059334 1.0 0.3689112999946082 23 P09601,P20020,Q9HB40,Q9NZ08,P09493,P42892,Q9UIQ6,P42785 8 +Lysosomal transport 0.4471025958685066 2.0336480079481283 0.0419870977430099 1.0 0.3721686547921511 52 O95295,P46934,Q8N1B4,Q9HD42,Q9Y2T2,P13473,Q9NZJ7,Q07954,P11717,Q96L92,Q9Y3E7,P11279,O14964,Q14108,Q96ED9,O15118,P07602,Q9UID3 18 +Regulation of protein folding 0.8835746653948324 2.0300433506152795 0.0423521329844285 1.0 0.3739130732173871 4 O14737 1 +Chloride transmembrane transport 0.7146974542123452 2.0212704117338234 0.0432517803174983 1.0 0.3792892788642486 7 Q9UHG3,P51797,P55011,P51790 4 +Respiratory chain complex iii assembly 0.8235550574905279 2.011424604032233 0.0442806266862558 1.0 0.3852297377189218 5 Q69YU5,Q9BSK2 2 +Fatty acid transmembrane transport 0.6738060331483386 2.006159056555803 0.0448392806467521 1.0 0.389060618487716 8 P23786,P33897,O14678 3 +Glutamate receptor signaling pathway 0.8772919605077598 2.004035523322456 0.0450662552755227 1.0 0.3900633306907197 4 Q92542,P05067,Q8NCG7 3 +Antigen processing and presentation of endogenous antigen 0.7104514359412526 2.0000156211193465 0.0454985771240448 1.0 0.3908771756080363 7 P10321,Q03518,P04439,Q9NZ08 4 +Antigen processing and presentation of endogenous peptide antigen 0.7104514359412526 2.0000156211193465 0.0454985771240448 1.0 0.3908771756080363 7 P10321,Q03518,P04439,Q9NZ08 4 +Oligosaccharide metabolic process 0.768587038812168 1.999988554187172 0.045501499851499 1.0 0.3908771756080363 6 P10253,P06280,P17900 3 +Positive regulation of mitophagy 0.8753173483780057 1.9958486079331648 0.0459504040686447 1.0 0.3914712533153837 4 P27544,P12235,P21796 3 +Lipid biosynthetic process 0.3558884167904744 1.9946114411355989 0.0460852747786328 1.0 0.3921123573338532 163 P54619,P33897,Q96G23,Q06136,Q9H7Z7,Q9NZ01,Q16880,Q14849,Q8N5B7,Q9HBU6,Q9H490,Q15392,Q96PU8,P05023,P37268,Q9H2C2,Q9P035,Q9NPH0,Q8NBX0,Q92643,O95470,Q53H12,P04062,P49327,Q13510,Q8NF37,Q14534,Q16739,O43292,Q8WTV0,Q86YN1,Q9UKU0,P27544,Q16822,Q9NX62,O75845,Q92604,Q9HCL2,P04035,Q15125,Q9BTU6,Q9UG56,Q9NP80,Q15800,P42345,Q96N66,Q16850,Q99805,O14735,Q8NCC3,P16435,Q10713,Q53GQ0,Q8TBX8,P30536,Q5H8A4,O15269,Q9BY49,Q99758,Q14739,Q8NCG7,Q9NRA0,Q9NUQ2 63 +Positive regulation of chemokine production 0.7089383948990707 1.992430514190992 0.0463238421051452 1.0 0.3922093612650422 7 P09601 1 +Chemokine production 0.7089383948990707 1.992430514190992 0.0463238421051452 1.0 0.3922093612650422 7 P09601 1 +Negative regulation of macroautophagy 0.586407084383014 1.9922816893061412 0.0463401595957757 1.0 0.3922093612650422 13 P09601,Q8WVM8,O15118,Q9NQ88,P42345 5 +Endothelial cell proliferation 0.5387230123706636 1.9911108205670356 0.0464687051173613 1.0 0.3922093612650422 17 P09601,Q9H2J4,P57105 3 +Ph reduction 0.5572496233877948 1.990692589458863 0.0465146939243039 1.0 0.3922093612650422 15 Q8N511,Q93050,P51790,Q9P0T7,P50897,Q9Y487,O75503 7 +Mitochondrial atp synthesis coupled proton transport 0.6314776350524359 1.9901560910567313 0.0465737435225783 1.0 0.3922093612650422 11 P56385,O75964,P00846,P06576,P24539 5 +Chondrocyte differentiation 0.5842271778436583 1.9785268997544776 0.0478692970573504 1.0 0.3998278684183055 13 P16435,Q9NX62,Q92896,Q15043,Q8N5W9 5 +Protein localization to organelle 0.3312281057305494 1.974906914783426 0.0482787125530381 1.0 0.4004149967986533 360 Q15154,O60830,Q8N4H5,P49458,P24390,P52789,Q9NS69,Q8N1F7,P11233,Q99595,O15258,Q5JTV8,Q9Y6C9,P46934,Q9Y584,Q15005,Q15006,O14925,Q9HD47,Q9H1Z9,O14773,Q9Y6X3,Q53FT3,Q8NFH5,Q99623,Q8WWC4,O43731,P49257,Q9UII2,Q9Y512,O14737,Q5JRA6,Q13438,Q9Y5M8,Q9P0J0,P40616,Q14108,P61026,Q9H4A6,Q8N4V1,Q15629,P02545,Q15070,Q9BRG1,Q9NQC3,P51572,P52292,Q8TB36,Q96A33,Q9Y5J9,Q96A65,Q8N2H4,P53350,P02786,Q9Y2T2,O43681,Q96RL7,O60220,Q96HY6,Q96JH7,Q9NPA0,Q92973,P40855,O14964,O94901,P62258,Q15388,Q14789,O15397,Q8N8Q8,Q7Z4Q2,Q9Y5J6,P07900,Q9UPT5,Q7Z5K2,Q9P0I2,O43292,P12270,O95429,Q9H4M9,O43615,Q99442,P78371,O96008,O75312,Q9Y276,Q9GZY8,P11279,Q9H300,Q5JRX3,A0AVF1,Q9Y5K8,Q13561,Q9Y3D6,P30536,Q9NV96,Q9UHB9,O75381,Q8TD16,Q9UH99,P13473,Q7Z3B4,Q53H12,Q8NEY8,P46379,Q9Y5L4,O95373,Q9Y371,Q8IZ07,Q15643,P49755,Q10713,O00429,Q06481 114 +L alpha amino acid transmembrane transport 0.6532918903645131 1.9727780663515395 0.0485208531594443 1.0 0.4019164373169588 10 Q9Y619,O60831,O75746,O75915,P30825,Q9UJS0,Q9H936,P08195,Q15758 9 +Protein hydroxylation 0.5293490139919346 1.9714501150928545 0.0486724135999769 1.0 0.4026647349019479 18 P07237,Q9H267,Q92791,Q32P28,O15460,Q96AY3,P13674 7 +Neuron apoptotic process 0.4438081925748648 1.9678664314997432 0.0490834080942563 1.0 0.4035269687949052 56 P07196,Q9NR28,O75312,Q96A26,Q01105,P09601,P04062,Q99720,P50897,O76024,P05067,Q07820 12 +Lipid translocation 0.7034369816182297 1.964802184188007 0.0494371373147699 1.0 0.4052902468607376 7 Q99758,Q9NV96,P33527,Q96AA3 4 +Smad protein signal transduction 0.650542174487525 1.9575896526459944 0.0502781824992153 1.0 0.4097640722395778 10 Q8N1F7,Q07954,Q96PK6,Q01082,O00400,P08670,Q9UIQ6 7 +Fatty acid transport 0.5271221796454698 1.9552199147007303 0.050557118990627 1.0 0.4110187535245418 18 P23786,P33897,Q9Y3D6,O43808,O14678,Q9NP80 6 +Skeletal system morphogenesis 0.5017609879199436 1.9461038453777333 0.0516422667820171 1.0 0.4119840513562351 21 O75844,P16435,Q92896,Q9NX62,O95470,Q8N5W9 6 +Early endosome to golgi transport 0.698715014583181 1.9410274578953028 0.0522549469620161 1.0 0.4140732363484099 7 O15260,Q13190,O60499 3 +Vacuolar localization 0.4912113138145675 1.936760790832523 0.052774590868448 1.0 0.4164441893890727 22 O95295,Q9BZG1,Q9H267,O60271,P09601,Q99584,P78537,Q9NRA0,Q6IAA8,P33176,Q86YV9 11 +Connective tissue development 0.4489714630048466 1.935608625303065 0.0529156531783863 1.0 0.4167979053344273 30 O75844,O15173,Q92896,Q9NX62,Q9C0B1,P16435,Q96HY6,Q15643,Q15043,P43490,Q8N5W9,Q8N0X7 12 +Glycoside catabolic process 0.7513406717471232 1.919912211332126 0.0548689892030409 1.0 0.4235602605497656 6 P08236,Q9NUJ1,P04062,Q9BTY2,P06280 5 +Peptidyl proline hydroxylation 0.6569447657693502 1.9162012650458995 0.055339482421675 1.0 0.4261652608846711 8 P07237,Q32P28,O15460,O75718,P13674 5 +C4 dicarboxylate transport 0.6456889739150145 1.9137874039819336 0.0556473255993796 1.0 0.4261652608846711 9 O75746,Q9UJS0,Q9H936,Q9UBX3,P55011 5 +Atp synthesis coupled proton transport 0.5929778786930456 1.9125766106504825 0.0558022763274355 1.0 0.4261652608846711 12 P56385,O75964,P00846,P06576,P24539 5 +Negative regulation of transporter activity 0.5730672623209316 1.9078227557310503 0.0564141285926396 1.0 0.4269686119146038 13 Q96PU5,P46934,P62942 3 +Prostate gland development 0.7477577290074373 1.903198181628645 0.0570146903493948 1.0 0.4277345468508601 6 P04083,Q02790,Q9NZJ7,P07602 4 +Proteoglycan metabolic process 0.6432117868397415 1.9001992228541045 0.0574069802398871 1.0 0.4295400557880973 9 Q8NCH0,Q9NX62,Q7LGA3 3 +Mitochondrial fission 0.5349655790513923 1.8987589366133155 0.0575961785333352 1.0 0.4304659843338019 16 Q9Y3D6,O00429,Q9UDX5,P11233,O60313,Q9NUQ9 6 +Sphingosine biosynthetic process 0.7969600013955145 1.895093110335202 0.0580800672581756 1.0 0.4316793939937263 5 O15269,P04062,Q13510 3 +Tetrapyrrole biosynthetic process 0.542956930495633 1.8938695586426977 0.0582423259909645 1.0 0.43192450330948 15 P22830,O00264,P30536,O75027,Q9P0S9,Q7KZN9,Q9UII2 7 +Peroxisome organization 0.5510568540844543 1.89319811094094 0.0583315285416574 1.0 0.4320343054262174 14 P33897,O75381,P28288,Q9Y3D6,Q9GZY8,O00429,O14678,P40855,P56589,P22307,O14734 11 +Negative regulation of cytokine production 0.4504683067491737 1.883267902362794 0.0596640709821603 1.0 0.4376187311275683 27 P33897,P09601,P04062,P30536,P20020,Q07021,Q06481 7 +Glycosylceramide metabolic process 0.7941270556828995 1.882627310418743 0.0597508925881946 1.0 0.4376187311275683 5 P06280,Q16880,P04062 3 +Negative regulation of ion transport 0.5168963716331572 1.8803757354523771 0.0600568880982634 1.0 0.4388823922469765 18 Q96PU5,P46934,P62942,P21796 4 +Positive regulation of autophagy 0.431716799353281 1.8796453755877744 0.0601564247800241 1.0 0.4389928916779589 34 Q9Y371,P27544,P09601,P21796,Q86UE4,O15269,P05141,P12235 8 +Endosome organization 0.421728193733755 1.8783221355792517 0.060337110183217 1.0 0.439465308610209 37 Q9H267,Q9UQN3,Q92783,Q9BRG1,Q6IAA8,Q9HD42,Q86VS8,Q9BTU6,P61020,Q9P0T7,Q8WUX9,O43752,P51790,Q9Y3E7,Q14108,O14964,Q96ED9,Q12768,Q9P253 19 +Glycosaminoglycan catabolic process 0.789939306062719 1.8641745129747096 0.0622972012998142 1.0 0.4459716621615976 5 P54802,P15586,P16278 3 +Aminoglycan catabolic process 0.789939306062719 1.8641745129747096 0.0622972012998142 1.0 0.4459716621615976 5 P54802,P15586,P16278 3 +Adp transport 0.8437235543018388 1.864045358401452 0.0623153348831546 1.0 0.4459716621615976 4 P05141,P12236,P12235 3 +Regulation of sodium ion transport 0.5206365341762814 1.8619889384737904 0.0626046494277148 1.0 0.4468820014422782 17 P46934,O43707,P50570,Q96PU5,Q9HD47,P27105,P05026,P23634,P05023 9 +Vacuolar transport 0.4380487481999953 1.8615387311083125 0.0626681363964907 1.0 0.4468820014422782 63 Q8N1B4,P13473,Q9NZJ7,Q9BRG1,Q9HD42,P46934,Q07954,O15118,P07602,Q9UID3,O95295,Q9Y2T2,Q96RL7,P11717,P11279,Q96L92,Q9Y3E7,Q14108,O14964,Q96ED9 20 +Maternal process involved in female pregnancy 0.6467103180829468 1.8612114595625828 0.0627143207132769 1.0 0.4468820014422782 8 P35613,Q9BQE5 2 +Entry into host 0.4295048765196294 1.8577902663556864 0.0631988039232598 1.0 0.4469284401106984 34 P07237,Q9UPT5,Q9BTY2,Q8WTV0,P11279,Q14108,O15118,P35613 8 +Iron ion transmembrane transport 0.7380442584437298 1.8577533736527976 0.0632040451959974 1.0 0.4469284401106984 6 Q9NP58,O75027,Q8N4V1,Q15043 4 +Regulation of er to golgi vesicle mediated transport 0.6789116718916424 1.840718483656821 0.0656628238313126 1.0 0.4584547689368822 7 Q9NR31,Q9P2W9,Q8WVM8,Q969M3 4 +Regulation of oxidoreductase activity 0.5037492572120331 1.8339665822190896 0.0666589548633935 1.0 0.4640979100762343 19 P16435,P06280,Q99623,Q04656,Q9P0J1,Q15070,Q8WTV0,Q9NRA0,P23634,P00374 10 +Negative regulation of calcium ion transport 0.6416295411727879 1.833806234891605 0.0666827619008729 1.0 0.4640979100762343 8 P62942,P21796 2 +Organelle localization 0.2925053436094582 1.8327336535635577 0.0668421899781865 1.0 0.4647157330724452 202 Q8WXH0,Q15154,Q9BZG1,Q9H267,P61026,O43707,O75381,Q8TD16,Q9UH99,P09601,P02545,Q15363,Q14849,O95721,P07196,Q9HD42,Q5SNT2,P62820,Q15058,O60499,O15400,Q86YV9,Q86Y82,P53350,O95295,Q9Y2T2,P16615,Q96A57,Q15643,Q92905,P49755,O60313,O15498,Q9NR31,O75153,Q14203,P11279,Q8IWA4,Q7Z6M1,P42345,A0FGR8,Q13190,Q12846,O43752,Q9Y6D9,Q96DB5,O00429,O00560,Q99584,P78537,Q9Y3E7,Q9NRA0,O14964,Q6PJG6,Q9UBK9,Q9BZD4,O94901,O95772 58 +Cerebellar purkinje cell layer morphogenesis 0.7325305441898308 1.8318723366259384 0.0669704428823172 1.0 0.4651157368922919 6 O15020,P04062,Q15058,Q96D53 4 +Manganese ion transmembrane transport 0.8357606734308907 1.8305923536100168 0.0671614107047893 1.0 0.4654590075926231 4 Q9HD20,Q9HC07 2 +Manganese ion transport 0.8357606734308907 1.8305923536100168 0.0671614107047893 1.0 0.4654590075926231 4 Q9HD20,Q9HC07 2 +Signal peptide processing 0.7320108330957232 1.8294297139841 0.0673352596561038 1.0 0.4661726344823107 6 O75503,Q15005,P67812,Q9H300 4 +Negative regulation of calcium ion transmembrane transport 0.6762538705600284 1.8271836402254311 0.0676721627931233 1.0 0.4678217553035574 7 P62942,P21796 2 +Sensory perception 0.4162407731603763 1.8209285178182344 0.0686177235488227 1.0 0.4692006804463435 41 Q6P4Q7,Q9BRK0,O60313,Q9Y5J9,P50897,Q14108,O76024,P23634,Q9H6K4 9 +Neutral lipid biosynthetic process 0.639100370289876 1.8201382782591873 0.0687379496227393 1.0 0.4694594960215544 8 Q92604,Q8WTV0,Q9HCL2,Q8NCC3 4 +Sulfur compound catabolic process 0.60146733541779 1.8155964510276643 0.0694322984272886 1.0 0.4698109328768282 11 Q9UJ14,P33897,P16278 3 +Oligosaccharide lipid intermediate biosynthetic process 0.7287443772915143 1.814065250748343 0.0696676806249056 1.0 0.4702315641658352 6 Q9BT22,Q86YN1 2 +Long chain fatty acid transport 0.5302249644226017 1.8068853988574576 0.070780149596433 1.0 0.4721378732931947 15 P23786,P33897,P50416,O14678,Q9NP80 5 +Regulation of stem cell population maintenance 0.8291648786700547 1.802814625477151 0.0714173324718752 1.0 0.4754167972343352 4 Q9Y6J9 1 +Regulation of leukocyte degranulation 0.6254163790654951 1.802072110331897 0.0715340609945749 1.0 0.4755605658412147 9 P09601,Q9NRA0,P11279 3 +Bone remodeling 0.6357040979141763 1.8017576548535756 0.0715835426764182 1.0 0.4755605658412147 8 O14773 1 +Tail anchored membrane protein insertion into er membrane 0.5988202865189259 1.8000638287162234 0.0718505602303085 1.0 0.476372111526955 11 O43681,Q8N4V1,Q9NPA0,Q15006,P46379,Q9P0I2,Q5J8M3 7 +Phosphatidylethanolamine metabolic process 0.7741976092926145 1.7945444917135032 0.0727263038530101 1.0 0.4792794593599677 5 Q9NP80,Q9HBU6,Q8NCC3 3 +Organic cation transport 0.7242788932915236 1.7930269957635168 0.0729686075939464 1.0 0.480394927072458 6 Q9HC21,O43808,Q70HW3 3 +Necrotic cell death 0.5197954713407709 1.7924580819864722 0.0730596180735456 1.0 0.4803970687268343 16 P30536,O00429,Q13510,P00403,P12235 5 +Regulation of sodium ion transmembrane transport 0.5280058921334022 1.7916561744133417 0.0731880588207827 1.0 0.4803970687268343 15 P46934,O43707,P50570,Q96PU5,Q9HD47,P05026,P27105,P23634 8 +Negative regulation of lymphocyte mediated immunity 0.8248236953455566 1.7844991457240722 0.0743425934968633 1.0 0.4852563148054218 4 P46108,Q96FV9,P04439 3 +Cellular hormone metabolic process 0.5033560306748105 1.7804997439850931 0.074994211188001 1.0 0.485469416322326 18 Q53GQ0,O95470,P30536,Q9HB40,Q14849,Q6UX07,P42892 7 +Establishment of protein localization to vacuole 0.4717167163190552 1.7775203658415293 0.0754826630584202 1.0 0.4876713899167286 22 P46934,Q9Y2T2,P13473,Q96RL7,Q9BRG1,Q14108 6 +Neuron recognition 0.7205141039548311 1.7752598497440375 0.0758549915947492 1.0 0.4882953361255062 6 P35613,Q9NQC3 2 +Regulation of necrotic cell death 0.5705898301455538 1.7751312991567716 0.0758762100532564 1.0 0.4882953361255062 12 P12235,Q13510,P00403 3 +Leukocyte mediated cytotoxicity 0.516445636277327 1.7688515827418252 0.076918645918603 1.0 0.4905992603278563 16 P46108,P15151,Q9BZM4,P01889,P04439,P11279,Q9NUQ9,O15400,P33176 9 +Intermembrane lipid transfer 0.5932025414935991 1.7670294073331585 0.0772233035086003 1.0 0.4905992603278563 11 P61916,P30536,Q9Y255,Q99758,Q14849 5 +Positive regulation of t cell mediated cytotoxicity 0.7674189185509577 1.764434332327678 0.0776588821784507 1.0 0.4905992603278563 5 P04439,Q9NUQ9,O15400 3 +Regulation of t cell mediated cytotoxicity 0.7674189185509577 1.764434332327678 0.0776588821784507 1.0 0.4905992603278563 5 P04439,Q9NUQ9,O15400 3 +Ceramide transport 0.767019965403208 1.762659924636956 0.0779578636602944 1.0 0.4905992603278563 5 Q9NZJ7,P07602 2 +Cellular response to biotic stimulus 0.4069716011977086 1.761012939698451 0.0782362129223916 1.0 0.4905992603278563 38 O75844,Q96A33,Q8WTV0,Q9NUQ9,O76024,Q86UE4,P08670 7 +Hormone metabolic process 0.4303503743905145 1.760095711993973 0.078391579712596 1.0 0.4905992603278563 30 O75844,P16435,Q53GQ0,Q6UX07,O95470,P30536,Q9HB40,O75787,Q14849,Q8TAD4,P42892 11 +Protein mannosylation 0.8189768755104526 1.759790998436453 0.0784432498772189 1.0 0.4905992603278563 4 O43505,Q6ZXV5 2 +Protein o linked mannosylation 0.8189768755104526 1.759790998436453 0.0784432498772189 1.0 0.4905992603278563 4 O43505,Q6ZXV5 2 +Aminoglycan biosynthetic process 0.61450975269763 1.7565242827971543 0.0789989288831252 1.0 0.4905992603278563 10 Q7LGA3,Q8NCH0,O43505 3 +Locomotory behavior 0.4248333023806138 1.7558447442599276 0.0791149219720102 1.0 0.4905992603278563 32 O75844,P10253,P54802,Q96RL7,P50897,P05067,O15118,P42345 8 +Regulation of triglyceride metabolic process 0.8180276870041143 1.7557755055858195 0.079126748363858 1.0 0.4905992603278563 4 Q96N66,Q8WTV0 2 +Cellular copper ion homeostasis 0.7163420829805267 1.7555391491991 0.0791671303220478 1.0 0.4905992603278563 6 O75880,O43819,Q04656,Q9NP58,P05067 5 +Peroxisomal transport 0.6269012229936328 1.7539760498545611 0.0794346110800483 1.0 0.4905992603278563 8 P33897,O75381,P40855 3 +Copper ion homeostasis 0.6615873062656858 1.7521960904560487 0.0797400956804741 1.0 0.4905992603278563 7 O75880,O43819,Q04656,Q9NP58,P05067 5 +Gpi anchor metabolic process 0.6264346680225171 1.7514380373920209 0.0798704857604337 1.0 0.4909422288283858 8 O43292,Q9H490,Q5H8A4 3 +Acidic amino acid transport 0.6131675614580503 1.7489642667489598 0.0802971963378653 1.0 0.4931042579963963 10 O60831,O75746,O75915,Q9H936,Q9UJS0,Q8IWT6,P05556,Q8TDW0,P55011 9 +Nuclear pore organization 0.5478087323868903 1.7460794499186736 0.0807971471527817 1.0 0.4948648001363527 13 Q9BTX1,Q7Z3B4,Q8N1F7,Q9NQC3 4 +Steroid biosynthetic process 0.4149746932912117 1.740237457299678 0.0818173309349328 1.0 0.4986048195857319 47 Q9H2C2,Q16850,P16435,Q53GQ0,O75845,P30536,Q13510,Q14534,P04035,Q15125,Q14849,Q14739,Q15800,Q15392 14 +Vacuolar acidification 0.5886056747417211 1.739928449646483 0.0818715824194897 1.0 0.4986048195857319 11 Q8N511,Q93050,Q9P0T7,P50897,Q9Y487,O75503 6 +Regulation of lipoprotein metabolic process 0.7618863349076476 1.7398047876060054 0.081893301541867 1.0 0.4986048195857319 5 P04062 1 +Associative learning 0.5461386411624825 1.7353045578568105 0.0826868748810329 1.0 0.4993862039417391 13 P05067,O00264,P50897,P04035 4 +Regulation of gtp binding 0.7117627682799953 1.7338554003550202 0.0829437429504387 1.0 0.5004779792523261 6 O75503,P48729,Q9Y2S7,Q14155 4 +Regulation of translational initiation by eif2 alpha phosphorylation 0.8125893859548798 1.7327462848438218 0.0831407739322629 1.0 0.5005677982377795 4 Q15363 1 +Regulation of retrograde protein transport er to cytosol 0.7601959279552166 1.7322699765947904 0.0832255049448942 1.0 0.5005677982377795 5 Q13438,P51572,Q9GZP9 3 +Cobalt ion transport 0.9574288130814776 1.7282092007962504 0.0839507247713382 1.0 0.5010723027085181 2 Q8N4V1 1 +Negative regulation of glycoprotein metabolic process 0.8114462794379373 1.7279007720398876 0.0840060159024669 1.0 0.5010723027085181 4 Q9NQX7 1 +Transepithelial transport 0.7098658517561388 1.7248617758067748 0.0845523855798031 1.0 0.5021863828406384 6 P33527,Q86WC4,P08183,P55011 4 +Glycerolipid biosynthetic process 0.4188801604173763 1.7246248735221708 0.0845950978671556 1.0 0.5021863828406384 53 Q9HBU6,Q9H490,Q9NPH0,Q92643,Q8NF37,O43292,Q8WTV0,Q16822,Q9NX62,Q9NTJ5,Q92604,Q9HCL2,Q9BTU6,Q9UG56,Q96N66,Q10713,Q8NCC3,O14735,Q8TBX8,Q5H8A4,Q9NUQ2 21 +Microtubule anchoring 0.5624249459870877 1.7245906822266257 0.0846012638265816 1.0 0.5021863828406384 12 Q15154,O75381,Q9P287,Q8TD16,O95684 5 +Chromosome organization involved in meiotic cell cycle 0.4819285074557273 1.7224643466869454 0.0849854360095514 1.0 0.5033008661534134 20 P30153,Q92791,Q9BXW9,P46379,Q9BTX1,Q96KQ7,O94901 7 +Positive regulation of jnk cascade 0.6208988303150592 1.7212816165560894 0.085199733714891 1.0 0.5034442152938388 8 P05067,Q969S3 2 +Antigen processing and presentation of peptide antigen 0.5253216456045311 1.7208808748672604 0.0852724427303233 1.0 0.5034442152938388 14 P01889,P10321,Q03518,P04439,Q9NZ08,Q9UIQ6,Q99538 7 +Negative regulation of intrinsic apoptotic signaling pathway 0.4151820696263829 1.7153318351710067 0.0862844050261846 1.0 0.5042461090991645 34 P45880,Q8N2F6,O60313,Q9P0J0,Q86TM6,Q9H300,Q07820,O76024 8 +Vitamin d metabolic process 0.8084626234132746 1.7152455029439142 0.0863002254855387 1.0 0.5042461090991645 4 P04062,Q99538,P38435 3 +Macromolecule depalmitoylation 0.756376302798056 1.715228136409879 0.0863034082017812 1.0 0.5042461090991645 5 P50897 1 +Iron ion homeostasis 0.4808044223444738 1.713651299361399 0.0865927860671433 1.0 0.5042461090991645 20 Q8N511,P09601,Q15043,Q9NP58,O75027,Q15904,Q9Y487,P30519,Q92859 9 +Cellular response to increased oxygen levels 0.6194171156438256 1.7131969787905053 0.08667630727417 1.0 0.5042461090991645 8 Q8N511,Q15904,Q9Y487 3 +Icosanoid transport 0.7552080289678741 1.7100112460070485 0.0872637934759279 1.0 0.505276285782639 5 Q9NP80,P33527,O15439 3 +Amino acid import 0.6527385657820449 1.7067169079037068 0.0878746830132382 1.0 0.5061254658101411 7 Q96NB2,O75915,P30825,P08195,Q9H9B4,Q15758 6 +Membrane protein ectodomain proteolysis 0.6080848784620906 1.7056680767429238 0.0880698965397865 1.0 0.5061254658101411 9 Q92542,P38159,Q9NZ08,Q8TCT8 4 +Cobalamin metabolic process 0.8059059088829346 1.7043921872872114 0.0883078425328147 1.0 0.5061254658101411 4 P33527 1 +Positive regulation of nitric oxide synthase activity 0.9495348181561832 1.6954263891842671 0.0899945633681604 1.0 0.5093121978165902 2 P00374 1 +Positive regulation of i kappab kinase nf kappab signaling 0.4065066761671142 1.6943334934558936 0.0902019294654206 1.0 0.5093121978165902 43 O43657,Q5T9L3,P09601,Q8TB61,Q99584,Q86UE4,P62942 7 +Positive regulation of erad pathway 0.802927821055151 1.6917398942845672 0.0906955782878131 1.0 0.5107061801360849 4 Q4ZIN3,P46379 2 +Neural retina development 0.6495835588950706 1.690459663426634 0.0909400489331544 1.0 0.5113243907535984 7 P20020,P23634,P54802 3 +Positive regulation of protein exit from endoplasmic reticulum 0.7504247176781527 1.688630065523244 0.0912903452718558 1.0 0.5113266740951132 5 Q9NR31,Q92544,Q9NV96 3 +Multicellular organismal movement 0.6049808100216317 1.688319137064506 0.0913499835885294 1.0 0.5113266740951132 9 P10253 1 +Response to increased oxygen levels 0.5797747377334623 1.6876942343688508 0.0914699391487381 1.0 0.5115627464126281 11 Q8N511,Q15904,P00846,Q9Y487 4 +Regulation of lymphocyte apoptotic process 0.6485634384368448 1.685198545527013 0.0919502716004263 1.0 0.5129405736352876 7 Q9HCL2 1 +Leukocyte degranulation 0.5108057548083663 1.6729533695455516 0.0943364761283747 1.0 0.5213873978960676 15 P09601,Q9NRA0,Q99584,P11279 4 +Negative regulation of sodium ion transmembrane transport 0.9433323935720276 1.6696416058382677 0.0949902934509794 1.0 0.5223671906581034 2 P46934 1 +Lipoprotein localization 0.6980091518731134 1.6684990084574984 0.0952167085992337 1.0 0.523174847499716 6 A6NIH7,O15260,Q5JRA6 3 +Monocarboxylic acid transport 0.6106560833352657 1.665284760320361 0.0958559574933797 1.0 0.5251323725789726 8 O95563,O15439,P53985,Q9NP80 4 +Chloride transport 0.5012575653820811 1.66124499446497 0.0966642522865572 1.0 0.5262920424575226 16 P51797,Q96S66,P30536,Q9NW15,P51790,P08183,Q9C0H2,Q9UHG3,Q86WC4,P55011 10 +Peptidyl proline modification 0.3986993841399311 1.6606719238144207 0.0967793551482898 1.0 0.5264828939704733 39 P07237,Q32P28,Q9Y680,P26885,Q02790,Q00688,Q96AY3,Q9NWM8,P13674,O95302,P62942 11 +Cellular pigmentation 0.5344672485366122 1.6597416760501984 0.0969664314127811 1.0 0.5266294132137587 13 O95295,Q9BXS5,Q9H267,P62820,P78537,Q13637,Q9NP58 7 +Import across plasma membrane 0.4737216561407755 1.6579849640543456 0.0973205012846902 1.0 0.5275848496795855 20 P54709,Q15758,Q9BXP2,O75915,P98164,P30825,P31751,Q15043,P55011,P05026,P05556,P08195,P23634,P05023 14 +Regulation of atp metabolic process 0.4147759221004151 1.6576753959956665 0.0973830025104176 1.0 0.5275848496795855 32 P33897,O75746,Q9BSK2,O14548,Q9Y3D6,Q9NQ88,P30536,O00429,P00403,Q9NRA0,P05067,P14406,Q9UII2 13 +Regulation of autophagy of mitochondrion 0.4865418729506414 1.6553171262185338 0.0978601867218398 1.0 0.5288540990584398 18 P27544,P30536,O00429,P21796,P05141,Q9H300,P12235 7 +Peripheral nervous system development 0.5337457237921929 1.65505568660425 0.0979132025741298 1.0 0.5288540990584398 13 Q16880,P51648 2 +Adult locomotory behavior 0.5080023779918215 1.6534998946622466 0.098229167527583 1.0 0.5295518318269784 15 O75844,P05067,P50897,O15118 4 +T cell mediated cytotoxicity 0.6417584295460144 1.6500462238454137 0.0989334822716929 1.0 0.532009176390482 7 P04439,Q9NUQ9,O15400 3 +Peptide catabolic process 0.5503843594745396 1.649679282243656 0.0990085497798312 1.0 0.532009176390482 12 Q9UJ14,P42892,Q9NZ08,O14773 4 +Positive regulation of vasculature development 0.4470563204297209 1.6466124476367852 0.0996377302678444 1.0 0.5340809714520071 23 P09601,Q9H2J4,Q9NZ08,Q86UE4 4 +Regulation of ire1 mediated unfolded protein response 0.7409169951828778 1.6460312282831646 0.0997573298209477 1.0 0.5342866109384148 5 P57088,Q92905,Q96HY6 3 +Phosphatidylcholine catabolic process 0.792057049072366 1.6454652320990577 0.099873906866297 1.0 0.5344757408133732 4 Q8WTV0,Q8NCC3 2 +Response to manganese ion 0.6924419263637054 1.6419488439725094 0.1006006061500854 1.0 0.5347425358012023 6 P02786,P05067,P30536 3 +Cell adhesion molecule production 0.7904958092288422 1.6388080406927743 0.1012532440730549 1.0 0.5347425358012023 4 Q9H4A6,Q5KU26 2 +Protein targeting to vacuole 0.484261198601179 1.63824428179799 0.1013707456022239 1.0 0.5347425358012023 18 P46934,Q9Y2T2,P13473,Q96RL7,Q14108 5 +Diacylglycerol biosynthetic process 0.9357203270369336 1.637967597642217 0.1014284532519103 1.0 0.5347425358012023 2 Q9HCL2 1 +Regulation of macroautophagy 0.4158170516893156 1.6365548695579255 0.1017235120166997 1.0 0.5347425358012023 60 Q9Y371,P27544,P46934,Q9UPT5,Q93050,P09601,Q8TBX8,P04062,Q8WVM8,P21796,Q9Y487,O15118,O15269,P42345,P05141,P12235 16 +Late endosome to vacuole transport 0.5700727575370398 1.6300583151133834 0.103089172686444 1.0 0.5347425358012023 11 Q9HD42,Q8WUX9,Q92783,Q9Y3E7,Q9BRG1 5 +Amyloid precursor protein catabolic process 0.4964591883023734 1.6270614175474116 0.1037240542925412 1.0 0.5347425358012023 16 Q92542,O95197,Q9NQC3,Q15392,P62942 5 +Reactive oxygen species biosynthetic process 0.5289905017243993 1.6241313096311392 0.1043477870473721 1.0 0.5347425358012023 13 P33897,Q9BSK2,P00403,P51790,O75027,Q9NRA0 6 +Camera type eye morphogenesis 0.6365398511155258 1.623023765654526 0.1045843245880582 1.0 0.5347425358012023 7 O95140,P54802,Q8NBN7,Q9P273,Q16706 5 +Protein n linked glycosylation 0.4440182697643463 1.6206422915756309 0.1050943766394625 1.0 0.5348776526499502 23 Q9H3H5,Q2TAA5,P15291,Q9NYU2,P04844,P04843,Q86YN1,Q9BT22,P46977,P26572,Q9HC07,Q96AA3 12 +Regulation of translation in response to endoplasmic reticulum stress 0.7858172657704855 1.618842175509055 0.1054812250213672 1.0 0.5358332797048303 4 Q15363 1 +Regulation of response to osmotic stress 0.7849723341911492 1.6152338268290392 0.1062600677152687 1.0 0.5361954181558326 4 Q9BPX6,O95202 2 +Calcium ion export 0.7844851904090413 1.613153087922453 0.1067112525240996 1.0 0.5361954181558326 4 P20020,P23634,O95202 3 +Protein targeting to lysosome 0.5270547394587525 1.6115224009684053 0.1070659087607031 1.0 0.5375362457398047 13 Q14108,P13473,P46934,Q9Y2T2 4 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.6336226206970366 1.6078940479104442 0.1078583856610648 1.0 0.540277686590117 7 Q8N4V1,Q9P0I2,Q9NPA0,Q15006,Q5J8M3 5 +Glycolipid transport 0.7828973772057084 1.6063692826477678 0.1081927958857646 1.0 0.5410935093484203 4 Q9NZJ7,P07602 2 +Sodium ion homeostasis 0.5997298471408613 1.605278150781079 0.1084326053400057 1.0 0.5410935093484203 8 Q9Y5X3,Q96PU5,P55011,Q93063,P05026,P05023 6 +Regulation of plasma lipoprotein particle levels 0.4931386283488826 1.6033558786237538 0.1088561061930863 1.0 0.5411779927212822 16 P61978,P09601,Q6PIU2,Q8WTV0,Q9Y2B0,Q9H4M9 6 +Negative regulation of protein exit from endoplasmic reticulum 0.7817621057803716 1.6015172763890904 0.109262396636848 1.0 0.5419447833186646 4 Q13438 1 +Golgi vesicle budding 0.6315813950091296 1.5972975870188122 0.1101993884382943 1.0 0.5437075580730825 7 Q9H4A6,Q15363,P49755,Q8N6H7 4 +Positive regulation of long term synaptic potentiation 0.7805179952499475 1.596198543075242 0.1104444727969649 1.0 0.5437075580730825 4 P05067 1 +Interferon gamma production 0.5963246004628466 1.5865217253270587 0.112621007856803 1.0 0.5491248458513278 8 Q08722,P04439,Q9NUQ9 3 +Mitochondrial genome maintenance 0.5622318264366462 1.5832972352124175 0.1133537328009826 1.0 0.5491248458513278 11 Q9BSK2,O60313 2 +Mitochondrial protein processing 0.6286716271277577 1.5821783513992365 0.1136088609940291 1.0 0.5491248458513278 7 Q10713,Q9UJZ1,Q96TA2,Q9Y4W6,Q96E52 5 +Positive regulation of fatty acid metabolic process 0.7265015031909463 1.5812038052913076 0.1138314455831985 1.0 0.5491248458513278 5 Q92604,P33897,P50416 3 +Positive regulation of protein localization to cell surface 0.7261357034301276 1.5795552197705058 0.1142087612140354 1.0 0.5491248458513278 5 Q9HD47,Q12846 2 +Regulation of electron transfer activity 0.7764202208510186 1.57866868463377 0.1144120712688749 1.0 0.5491248458513278 4 Q9NRA0,Q99623 2 +Glycerophospholipid catabolic process 0.5854499900751641 1.5786182144024306 0.1144236542254997 1.0 0.5491248458513278 9 Q9NZC3,Q8WTV0,Q8NCC3 3 +Negative regulation of blood pressure 0.7763611137016284 1.5784157050001577 0.1144701395690441 1.0 0.5491248458513278 4 Q9HB40 1 +Protein o linked glycosylation via serine 0.7258690010760966 1.5783531392370709 0.1144845043316806 1.0 0.5491248458513278 5 Q8N4A0 1 +Microglia differentiation 0.9213419791373012 1.5780653440501642 0.1145505988304731 1.0 0.5491248458513278 2 P04062 1 +Antigen processing and presentation of exogenous peptide antigen 0.6783565287733639 1.5745451033262934 0.1153614828126263 1.0 0.5522070396351118 6 Q03518,P04439,Q9UIQ6,Q99538 4 +Signaling receptor ligand precursor processing 0.7246150333357856 1.5727000541096794 0.1157882873192279 1.0 0.5530425313715049 5 Q8TAD4,O75787,P42892 3 +Regulation of mast cell activation involved in immune response 0.7244078684424865 1.5717659318565094 0.1160048451720809 1.0 0.5532732898453783 5 P09601 1 +Regulation of mast cell activation 0.7244078684424865 1.5717659318565094 0.1160048451720809 1.0 0.5532732898453783 5 P09601 1 +Maintenance of location in cell 0.3980629924372418 1.5697628080613977 0.1164703030842144 1.0 0.554745020833632 46 P52789,P24390,Q9UH99,P10253,Q13438,Q96RL7,P30536,O43292,O43731,O95202,P62942 11 +Negative regulation of release of cytochrome c from mitochondria 0.6254672980375383 1.5655099188215644 0.1174633935007807 1.0 0.5574737026235534 7 Q9H3K2,Q9Y255,Q9H300,O60313 4 +Keratan sulfate metabolic process 0.9292160180485054 1.564393497574408 0.1177251868191981 1.0 0.5574737026235534 3 O43505,P16278 2 +Regulation of translation in response to stress 0.5358895028052495 1.5589374900329145 0.1190111759546499 1.0 0.5574737026235534 12 P51812,Q15363,Q15418 3 +Phosphatidylinositol biosynthetic process 0.4133440791840985 1.5585320809773804 0.119107169232097 1.0 0.5574737026235534 28 Q96N66,Q9NX62,Q10713,O14735,Q92643,Q8TBX8,Q5H8A4,Q9BTU6,O43292,Q9H490 10 +Linoleic acid metabolic process 0.7214589355377258 1.5584631942450793 0.1191234863510519 1.0 0.5574737026235534 5 Q9NP80,P33897,O60427 3 +Maintenance of protein location 0.399345210108268 1.5560404639932797 0.1196984706605843 1.0 0.5574737026235534 34 P52789,P24390,Q9UH99,Q13438,P30536,Q96RL7,O43292,O43731 8 +Atp biosynthetic process 0.444659383716561 1.5531312124160688 0.1203917907069356 1.0 0.5574737026235534 22 P56385,O75746,O75964,P00403,P00846,Q9NRA0,P06576,P24539 8 +Positive regulation of necrotic cell death 0.7195602061662782 1.5498923309851969 0.1211673606623215 1.0 0.5580531801692536 5 P00403 1 +Peripheral nervous system axon regeneration 0.7695435824015133 1.5492134453596025 0.1213304183851078 1.0 0.5580531801692536 4 P07196,Q96G23 2 +Positive regulation of mitochondrial calcium ion concentration 0.6730763833116489 1.5491970674997144 0.1213343542104352 1.0 0.5580531801692536 6 Q8IYU8,Q9BPX6,Q9Y3D6 3 +Regulation of reactive oxygen species biosynthetic process 0.5564224080987911 1.5485529707883567 0.1214892187268166 1.0 0.5583749766361097 11 P33897,Q9BSK2,P00403,P51790,Q9NRA0 5 +Cellular iron ion homeostasis 0.4852760722246807 1.5470693144607786 0.1218465323600153 1.0 0.5588456369120088 16 Q8N511,P09601,Q15043,Q9NP58,O75027,Q15904,Q9Y487 7 +Protein localization to lysosome 0.4851040707468214 1.5458356283588548 0.1221442700637456 1.0 0.5594309639340216 16 P46934,Q9Y2T2,P13473,Q14108,Q9NQC3 5 +Phosphatidylinositol metabolic process 0.4032679440499682 1.544507110044096 0.1224655301460893 1.0 0.5597944926460163 32 Q96N66,Q9NX62,Q10713,O14735,Q92643,Q8TBX8,Q92604,Q5H8A4,Q9BTU6,O43292,Q9H490 11 +Steroid metabolic process 0.4132298887308639 1.5444655937360183 0.1224755801790848 1.0 0.5597944926460163 72 Q9BQE5,Q14849,P05067,Q15392,P37268,Q9H2C2,P38435,O95470,P04062,Q13510,Q14534,Q8WTV0,O15118,O75845,P04035,Q15125,Q15800,Q16850,P16435,Q53GQ0,P30536,Q14739 22 +Regulation of steroid metabolic process 0.4923607127399044 1.5444515350735892 0.1224789835666135 1.0 0.5597944926460163 15 Q9H2C2,P16435,P30536,Q13510,O94905,Q6IAA8,P49748,P05023 8 +Positive regulation of oxidoreductase activity 0.5761334132776713 1.538568684909173 0.123909628419371 1.0 0.5641757268067493 10 Q8WTV0,P00374,Q9P0J1 3 +Antigen processing and presentation of peptide antigen via mhc class i 0.5319017710170093 1.53387367509866 0.1250607334091467 1.0 0.5668331819087373 12 P10321,Q03518,P04439,Q9NZ08,Q9UIQ6 5 +Retrograde transport vesicle recycling within golgi 0.7141647855530355 1.525514060412261 0.1271309292675817 1.0 0.5727119758857048 5 Q8WTW3,Q96JB2,Q8TBA6,Q9UP83 4 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.908655201578802 1.5251506040070033 0.1272215378241621 1.0 0.5727119758857048 2 P42892 1 +Negative regulation of interleukin 6 production 0.7635867853024578 1.523662151793436 0.12759312869641 1.0 0.5727119758857048 4 P04062 1 +Regulation of membrane depolarization 0.5728299146125703 1.5196467536857234 0.1285997806146761 1.0 0.5749835194444085 10 Q96PU5,P33897,Q9HD47 3 +Regulation of leukocyte mediated immunity 0.3954938537458739 1.5170472942268731 0.1292547437645108 1.0 0.5768281358050261 34 P46108,Q12846,P09601,P01889,P04439,P11279,Q9NUQ9,Q9NRA0,O15400,O96028,Q96FV9 11 +Copi coated vesicle budding 0.7122745129264404 1.5169652584235318 0.1292754557057334 1.0 0.5768281358050261 5 Q15363,P49755,Q8N6H7 3 +Response to muscle activity 0.7121819521813658 1.516546547162322 0.1293812097425963 1.0 0.5769086213403771 5 Q9UDX5 1 +Proteoglycan biosynthetic process 0.5834868471570398 1.5155904431661833 0.1296229450956907 1.0 0.5774474278081424 8 Q8NCH0,Q7LGA3 2 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.7118145886533114 1.5148846335463082 0.1298016224726597 1.0 0.5774474278081424 5 P46934,O14964 2 +Regulation of natural killer cell mediated immunity 0.665900184267976 1.5146808831826868 0.1298532379091139 1.0 0.5774474278081424 6 P46108,P04439,P11279 3 +Ire1 mediated unfolded protein response 0.6643437183973095 1.5071849538310609 0.1317632558380395 1.0 0.5837308434526127 6 P57088,Q92905,Q96HY6 3 +Vascular process in circulatory system 0.3842476061620089 1.5065898701994336 0.131915815505702 1.0 0.5837308434526127 39 P33527,Q16625,P30825,P98164,P53985,Q07954,P20020,Q9HB40,Q96QD8,P42892,P08183,P23634,O15439 13 +Homeostatic process 0.3060108172338043 1.5064695278544404 0.1319466839158942 1.0 0.5837308434526127 328 P06756,O75880,P52789,P09601,O75787,P50897,O75027,P30519,Q9Y6C9,Q9HC07,Q14157,Q8N511,Q9HD47,P22413,Q86YV9,O14773,P62942,Q7L0J3,Q96CP7,P10253,Q8WWC4,Q9UJZ1,Q9UII2,Q12846,Q92544,Q15067,Q9P0S9,P23786,P33897,Q9Y6N1,P53985,Q9NP58,Q9NQC3,Q8TAD4,P51572,Q96E52,P05023,Q9BWH2,Q5BJF2,Q96A33,P04062,P49327,Q8WTV0,Q9H9B4,O75503,Q15051,P02786,O95295,Q9HD20,Q9NX40,Q16822,Q9C0B1,Q96PU5,Q9HCL2,Q8N5M9,Q96RR1,Q07820,Q13586,Q15904,P51797,Q8NE01,P42785,Q16891,Q9Y6M7,O76024,P05067,O15260,Q8IYU8,Q8NF37,O15118,O95202,Q9UIQ6,Q92542,Q16625,Q6P4Q7,Q9Y3D6,P30536,Q93050,P13473,P23634,Q92859,Q9BPX6,Q9P035,Q16739,Q15043,P20020,P06576,P05141,Q16836,P16615,Q9Y487,Q9NP80,Q9P0T7,Q9NWR8,P51790,Q99758,Q06481 97 +Attachment of gpi anchor to protein 0.7097443237832339 1.5055161875700018 0.1321914182711694 1.0 0.5842896222913181 5 O43292,Q9H490 2 +Positive regulation of pattern recognition receptor signaling pathway 0.5701302426476239 1.5041667845721214 0.1325384278360371 1.0 0.5850370737433663 10 O75955,Q9NQC3 2 +Triglyceride biosynthetic process 0.6126165809793752 1.4984755287405207 0.1340097459340143 1.0 0.5890361403790577 7 Q16822,Q8WTV0,Q9HCL2,Q92604 4 +Neuron projection guidance 0.4291041275784483 1.4925044873231277 0.1355669417597511 1.0 0.5901215413308457 23 O15031,O00264,P42892,P05067,P35613 5 +Phosphatidylcholine acyl chain remodeling 0.9007612066535112 1.4922080649556682 0.135644608753692 1.0 0.5901215413308457 2 Q8NF37 1 +Adult behavior 0.4527332406653001 1.4917528400587745 0.1357639512403146 1.0 0.5901215413308457 20 O75844,Q92542,P51790,P50897,P05067,O15118 6 +Neutral amino acid transport 0.6601749929438308 1.4870921983471903 0.1369904617759967 1.0 0.5926396873847476 6 Q96NB2,Q9H2J7,P08195,Q9H9B4,Q96QD8 5 +Ornithine transport 0.8985057795320024 1.4827944443175591 0.1381290325952067 1.0 0.5939086433945456 2 Q9Y619 1 +Positive regulation of toll like receptor signaling pathway 0.6589079022592659 1.4809804102210131 0.1386117937677706 1.0 0.5939086433945456 6 Q9NQC3 1 +Neuron projection maintenance 0.7535545889682073 1.480560346550868 0.1387237686404159 1.0 0.5940014494453225 4 P05067,P33897 2 +Mast cell activation involved in immune response 0.5676045560705238 1.4776384933064326 0.1395045654035636 1.0 0.5954065714855533 9 P09601,Q99584 2 +Mast cell activation 0.5676045560705238 1.4776384933064326 0.1395045654035636 1.0 0.5954065714855533 9 P09601,Q99584 2 +L glutamate transmembrane transport 0.658118053724644 1.477169538342676 0.1396301970372566 1.0 0.5954693944179695 6 Q9UJS0,O75915,Q9H936,O75746 4 +Regulation of calcium ion import 0.6579067318085412 1.4761498136400493 0.1399036787537788 1.0 0.5958313508461242 6 P21796 1 +Vesicle targeting 0.4090174559652627 1.4720097606608318 0.1410182418210963 1.0 0.5979864451691493 25 Q15643,P49755,Q9NR31,Q15363,Q14849,O95721,O95772 7 +Positive regulation of endothelial cell proliferation 0.5425561427028618 1.465311437038043 0.1428359675542072 1.0 0.6032958332926702 11 P09601 1 +Regulation of entry of bacterium into host cell 0.749788434414695 1.464359073197719 0.1430958643662103 1.0 0.6032958332926702 4 Q9BTY2,P06756,Q9UPT5 3 +Neuron projection regeneration 0.5624113350863486 1.4598277411119114 0.14433742232584 1.0 0.6059348083411596 10 P07196,P00374,Q96G23 3 +Cellular respiration 0.3991894764474949 1.459756872854833 0.1443569051736133 1.0 0.6059348083411596 110 Q9UDW1,P33897,O14949,Q15070,Q9Y255,P00846,O43676,O95139,Q9NZ45,P56385,O14548,O75964,P04062,P00403,P21912,Q16134,Q9H3K2,O75746,O75208,P03886,Q13423,P13073,P14406,O96000,Q9BSK2,Q7KZN9,P24539 27 +Peroxisome fission 0.6994443452343254 1.4588392655919429 0.1446093525307628 1.0 0.6059348083411596 5 O00429,Q9Y3D6,P40855 3 +Endoplasmic reticulum unfolded protein response 0.4333949788867444 1.4587167026076493 0.144643097019252 1.0 0.6059348083411596 22 Q9Y4P3,Q9GZP9,Q96HY6,Q13438,Q92905,Q9BUN8,P57088,Q15363,O76024,Q6NTF9,Q7Z2K6 11 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7480492719231332 1.4568740329583192 0.1451511551312942 1.0 0.6068804045884012 4 Q03518,Q9UIQ6 2 +Protein deneddylation 0.5637484583673197 1.4557357506516082 0.1454656829089657 1.0 0.6074462199950907 9 Q99627,Q9UNS2,Q92905,Q9BT78 4 +Regulation of t cell apoptotic process 0.6984658958179397 1.454399685323164 0.1458355271511453 1.0 0.6086042272037328 5 Q9HCL2 1 +Eye photoreceptor cell development 0.7473661519166098 1.45393342469716 0.145964764836826 1.0 0.6087572976105295 4 P54802 1 +Chondrocyte development 0.9008017115636262 1.4532588631102523 0.1461518943147637 1.0 0.6090491736527778 3 Q9NX62 1 +Protein import 0.4069192892590993 1.453013682236596 0.1462199551767882 1.0 0.6090491736527778 90 Q15388,O75381,O60830,Q9NS69,P13473,Q8N1F7,Q99595,O15397,Q7Z4Q2,P52292,Q7Z3B4,O14925,Q9HD47,O43615,Q53FT3,O95373,Q8NFH5,O75312,Q99623,O14737,Q92973,P40855,Q06481 23 +Retina morphogenesis in camera type eye 0.7466328374791104 1.4507763863320755 0.1468421370889632 1.0 0.6104808695537997 4 P54802,Q8NBN7 2 +Positive regulation of vacuole organization 0.6518336487415004 1.446820579077382 0.1479471815081163 1.0 0.6122220255103238 6 Q9Y371 1 +Glial cell proliferation 0.6967010916094614 1.4463898584916084 0.1480678847411325 1.0 0.6122220255103238 5 P04062,Q96G23 2 +Maternal placenta development 0.7454991703261391 1.4458950429574673 0.1482066425039656 1.0 0.6122833465757426 4 P35613 1 +Export from cell 0.3567591603628936 1.4455393680882704 0.1483064433398329 1.0 0.6123110344294294 146 Q96PC5,P61026,Q9H4A6,P09601,Q32P28,P53985,P11233,Q9Y3C0,P50897,P04083,O95721,O15439,P05023,P55011,Q5T9L3,Q9UPT5,P62820,P20020,Q96A65,P05026,Q06787,Q86YV9,O95295,Q7L0J3,Q16822,Q16836,P16615,Q8N183,Q92905,Q8TBQ9,P49755,Q8N5M9,O15498,P50416,P04035,P11279,O43760,Q7Z6M1,P35580,Q16850,Q12846,Q5JRA6,O95563,Q96TA1,O00429,Q9BRK5,Q99584,O00560,P27824,Q96KC8,Q9Y3E7,P08183,O14964,Q9UBV2,Q9NRA0,P33527,Q96KP1,P62258 58 +Vesicle fusion with golgi apparatus 0.6962530320743827 1.4443558160695955 0.1486389125717293 1.0 0.6132987001155984 5 Q9BSR8,Q13190 2 +Regulation of autophagy 0.401455705649837 1.4427353752149985 0.1490950300236084 1.0 0.6144097822464115 104 Q93050,P09601,Q9NZJ7,Q8WVM8,P46934,Q9NZ45,Q9UPT5,P04062,O15118,Q86UE4,P07602,P05141,Q9Y371,P27544,P21796,Q9H300,Q07820,Q9Y487,P42345,P12235,O75844,P10619,Q8TBX8,P30536,O00429,O15269 26 +Autophagosome organization 0.3950037822117653 1.4407868959293233 0.1496448966359413 1.0 0.6160683742787626 31 Q9Y371,P53365,Q9H0U4,P16615,Q8TBX8,P04062,P62820,Q8WVM8,Q86Y82 9 +Epithelial cell differentiation involved in prostate gland development 0.8973433710247558 1.4397159279094476 0.1499477851640751 1.0 0.6164077121019547 3 P07602 1 +Regulation of morphogenesis of a branching structure 0.7437909952486139 1.4385383663470364 0.1502813597022865 1.0 0.6164077121019547 4 Q9NQC3 1 +Lipoprotein biosynthetic process 0.4576445156622971 1.4375464817311818 0.1505627752713532 1.0 0.6164077121019547 18 P04062,Q5H8A4,Q16739,O43292,Q9H490 5 +Multicellular organismal signaling 0.4037037770320425 1.4365302810178269 0.1508515061964992 1.0 0.6170089280188902 26 O75844,P16615,P04062,Q6PI78,P20020,Q9HD47,Q06787,P23634,P42345,P05023,P62258 11 +Regulation of programmed necrotic cell death 0.5593690212531599 1.4308282328981636 0.1524794494343693 1.0 0.6213784639905743 9 Q13510 1 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6482466838744527 1.4294769966650769 0.1528671819296598 1.0 0.6225433161308811 6 P46934,O14964 2 +Anterior posterior axis specification 0.5570695969855631 1.4290796813435664 0.1529813327540798 1.0 0.6226226643091481 10 Q15363,Q5T9L3,Q8N2A8 3 +Cerebellar cortex development 0.4612511391386177 1.4281678196429215 0.1532435606894118 1.0 0.623304204486247 17 P04062,P54802,O14949,Q96D53 4 +Negative regulation of production of molecular mediator of immune response 0.8844093600225417 1.423956588002997 0.1544590392333016 1.0 0.6270846302700153 2 P09601 1 +Cellular sodium ion homeostasis 0.6905968362373542 1.418663264768955 0.1559972119189174 1.0 0.6298303638985391 5 Q96PU5,P05023,P55011 3 +Regulation of cholesterol metabolic process 0.5971079142081162 1.4172156376581355 0.1564198911665464 1.0 0.6307624918469502 7 Q9H2C2,P16435,O94905,Q9UBM7,P49748 5 +Response to interleukin 12 0.8824358612912322 1.4157202343664077 0.1568574316539051 1.0 0.6317521910518884 2 Q08722 1 +Regulation of potassium ion transmembrane transporter activity 0.5341179295196516 1.4144623061098365 0.157226207305094 1.0 0.6322837653540082 11 P50570,Q96PU5,P46934,P62258 4 +Protein demannosylation 0.7380569729308373 1.4138299634043023 0.1574118336067016 1.0 0.6324359374656546 4 O60476 1 +T cell apoptotic process 0.533701321158813 1.4119484045514954 0.1579651537530426 1.0 0.6337863092278869 11 P24390,Q9HCL2 2 +Neuronal action potential 0.6890541347239544 1.4116510270341545 0.1580527398141982 1.0 0.6337863092278869 5 P04062,Q06787 2 +Mitochondrial respirasome assembly 0.8810262193402769 1.4098374642543074 0.1585876814751103 1.0 0.6340615082442559 2 P14406 1 +Secretion 0.3294422965123149 1.408369803468653 0.1590215958927869 1.0 0.6346254278734538 160 Q96PC5,P61026,P52789,P09601,Q9H4A6,Q32P28,P53985,Q9H7Z7,P11233,Q92783,P50897,P04083,Q9Y3C0,O95721,O15439,P55011,P55327,Q5T9L3,Q13505,Q9UPT5,P62820,Q9UNS2,P00403,Q96A65,Q06787,Q86YV9,O95295,Q7L0J3,Q16822,Q16836,P16615,Q8N183,Q92905,Q8TBQ9,P49755,Q8N5M9,O15498,P50416,P04035,P11279,O43760,Q9NP80,Q7Z6M1,P35580,Q16850,Q12846,Q04656,Q5JRA6,O95563,Q96TA1,O00429,Q9BRK5,Q99584,O00560,P27824,Q96KC8,Q9Y3E7,O14964,Q9NRA0,Q9UBV2,Q96KP1,Q9P253 62 +Negative regulation of nitric oxide metabolic process 0.6882832708454262 1.4081463997645984 0.159087723986564 1.0 0.6346254278734538 5 P06280,P30536 2 +Negative regulation of amyloid precursor protein biosynthetic process 0.8889485638046584 1.4068335336325273 0.1594767563855237 1.0 0.6346254278734538 3 Q9NQX7 1 +Positive regulation of mitochondrial translation 0.5549096933833927 1.4054332158012075 0.1598924954047078 1.0 0.6346254278734538 9 Q9Y2R0,Q9NWS8,Q567V2 3 +Regulation of phospholipase a2 activity 0.7355603024758337 1.4030655835880252 0.1605972829157869 1.0 0.6346254278734538 4 P50897,Q07954 2 +Glycosylceramide biosynthetic process 0.8793346489991454 1.402778579220228 0.1606828765489873 1.0 0.6346254278734538 2 Q16880 1 +Detection of biotic stimulus 0.6869419354318653 1.4020470818084998 0.1609011877292689 1.0 0.6346254278734538 5 Q8WTV0,P30536,P04439 3 +Natural killer cell mediated immunity 0.5109638696028154 1.4016597938775197 0.1610168622679686 1.0 0.6346254278734538 12 P46108,Q9BZM4,P01889,P04439,P11279,P33176 6 +Negative regulation of cell killing 0.734949900161827 1.400433321442638 0.1613835975803463 1.0 0.6346254278734538 4 P46108,P04439 2 +Response to corticosterone 0.878488863828591 1.399249337430463 0.1617382262147733 1.0 0.6346254278734538 2 P07196 1 +Chaperone mediated protein folding 0.3729423611322209 1.3986441630430966 0.1619197159899563 1.0 0.6346254278734538 38 O14737,P48723,Q9H2J4,Q32P28,P26885,P40855,P62942 7 +Regulation of long term synaptic potentiation 0.6410354757564205 1.3945664871262229 0.1631466069402911 1.0 0.6363226063654722 6 Q92542,P05067 2 +Respiratory gaseous exchange by respiratory system 0.5306630127669354 1.3936055884350045 0.1634367400238479 1.0 0.6363226063654722 11 P10253,O60476,Q16706,Q7KZN9 4 +Regulation of transmission of nerve impulse 0.8767972934874466 1.3921913010279154 0.1638644762754433 1.0 0.6363226063654722 2 P04062 1 +Regulation of neuronal action potential 0.8767972934874466 1.3921913010279154 0.1638644762754433 1.0 0.6363226063654722 2 P04062 1 +Carbohydrate derivative catabolic process 0.3752389256170721 1.3920700552828544 0.1639011849896912 1.0 0.6363226063654722 37 Q9BW91,P08236,P33897,P17900,P04062,Q13126,P54802,Q9BTY2,P06865,P06280,P15586,P16278 12 +Positive regulation of interleukin 1 alpha production 0.876515365097266 1.3910150235824268 0.1642208710537764 1.0 0.6363226063654722 2 Q99584 1 +Interleukin 1 alpha production 0.876515365097266 1.3910150235824268 0.1642208710537764 1.0 0.6363226063654722 2 Q99584 1 +Regulation of mitochondrial fusion 0.6402920991948486 1.390964614678393 0.1642361572488115 1.0 0.6363226063654722 6 Q9Y6C9,Q8N2A8,Q96E52 3 +Embryonic pattern specification 0.591492827828645 1.3877097809953765 0.1652254364425653 1.0 0.6384933710019969 7 Q15363,Q8N2A8 2 +Regulation of cellular respiration 0.4395098265665497 1.3861817840351571 0.165691402324041 1.0 0.6399015578891472 20 P33897,Q9NZ45,Q9BSK2,Q9Y255,P14406 5 +Phosphatidylcholine metabolic process 0.4697439306414439 1.3854497497529297 0.1659149877018058 1.0 0.6400956031782399 15 Q96N66,Q8NCC3,Q8NF37,Q8WTV0,Q9NP80 5 +Ubiquinone metabolic process 0.5594743314952124 1.3820968919069077 0.1669419526957976 1.0 0.6432069529854807 8 Q96D53,O75208 2 +Protein quality control for misfolded or incompletely synthesized proteins 0.4920408025314067 1.3816817436791502 0.1670694423531304 1.0 0.6432069529854807 13 Q16740,Q96E52,Q9BUN8,P46379 4 +Cellular macromolecule localization 0.3198449529189056 1.3814714331152425 0.1671340554435436 1.0 0.6432069529854807 616 Q15154,O60830,Q8N4H5,P43307,P24390,P49458,Q9NS69,P52789,Q8N1F7,P11233,Q99595,O15258,Q5JTV8,Q9Y6C9,Q9H490,Q9BXS5,P46934,Q9Y584,Q15005,Q15006,O14925,O60725,Q9HD47,Q9P2W9,O15400,Q9H1Z9,Q86YV9,O14773,Q86Y82,Q9Y6X3,Q53FT3,Q8NFH5,P57105,Q99623,Q8WWC4,Q14012,O43731,P49257,Q9UII2,Q9Y3A6,P10619,Q9Y512,O14737,Q12846,Q5JRA6,O43752,Q13438,Q92544,Q9Y5M8,Q9P0V9,Q9P0J0,P40616,Q14108,Q9UBV2,P35613,Q9BZG1,P61026,Q9H4A6,O00264,Q05D32,Q8N4V1,Q15629,P02545,Q15070,Q16880,Q13637,Q9BRG1,Q96CS3,Q9NQC3,Q99729,P51572,P52292,Q8TB36,Q5T9L3,Q9H0U4,Q92643,Q96A33,P62820,Q9BUN8,O60499,Q9Y5J9,Q07954,Q96A65,P27105,Q8N2H4,Q9C0E2,O75955,P53350,P02786,O95295,Q9HD20,Q96PU5,Q96RL7,Q969Q5,O60220,Q9GZP9,Q96HY6,Q9Y282,Q9NPA0,Q9HD45,Q15904,Q92973,P40855,Q15388,Q15363,O15397,Q8N8Q8,Q7Z4Q2,Q9Y5J6,O15260,Q9UPT5,Q9BRK0,O43292,Q86TM6,O15118,O43615,O75312,P50402,P11279,Q9H300,Q99805,Q16625,Q9Y3D6,P30536,Q96L92,Q9NV96,Q9UHB9,O75381,Q8TD16,Q9UH99,P13473,Q8WVM8,P23634,Q7Z3B4,Q53H12,Q8NEY8,P46379,Q9Y5L4,O95373,Q9Y371,Q8IZ07,P53365,Q15643,P49755,Q9NR31,Q16543,Q13190,Q10713,O00429,O00560,Q06481 151 +Collagen biosynthetic process 0.7295171031109424 1.3769969834231446 0.1685131804844233 1.0 0.6460119194996874 4 Q92791 1 +Neutrophil differentiation 0.7294781382228812 1.3768288436874108 0.1685651709036859 1.0 0.6460119194996874 4 Q8N5M9,P49327,Q14739 3 +Regulation of nitric oxide metabolic process 0.506701553454185 1.374635018759483 0.1692446262356994 1.0 0.6460119194996874 12 Q08722,P50570,P23634,P30536,P06280 5 +Autophagosome membrane docking 0.8722864392444327 1.3733732911490226 0.1696363285611881 1.0 0.6460119194996874 2 O95721 1 +Calcium ion import into sarcoplasmic reticulum 0.8722864392444207 1.373373291148973 0.1696363285612034 1.0 0.6460119194996874 2 O75844 1 +Very long chain fatty acid catabolic process 0.636406153130551 1.372127363564549 0.1700237924108285 1.0 0.6460119194996874 6 P33897,O14678 2 +Growth plate cartilage development 0.8799703868588447 1.37165943068185 0.1701694833876539 1.0 0.6460119194996874 3 O75844 1 +Bone growth 0.8799703868588447 1.37165943068185 0.1701694833876539 1.0 0.6460119194996874 3 O75844 1 +Glycosphingolipid biosynthetic process 0.8795826283135956 1.3701402680151695 0.1706431198727129 1.0 0.6464975803011712 3 Q16880,Q99805 2 +Zinc ion transport 0.8793006204173657 1.3690354181049131 0.1709882039324877 1.0 0.6470595036041263 3 Q8TAD4,Q8N1S5 2 +Azole transmembrane transport 0.8711587256836785 1.3686696875609636 0.1711025496924225 1.0 0.6471198788539754 2 P30825 1 +Folic acid metabolic process 0.55691551868625 1.3678185308284878 0.171368885777392 1.0 0.6476975631951992 8 P00374 1 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.678887430728899 1.3653937574128188 0.172129324889483 1.0 0.648606299558669 5 P13674,P07237 2 +Selective autophagy 0.3804761865090926 1.3641846426726574 0.1725094603524744 1.0 0.649081648019579 34 P27544,P53365,Q99623,Q96HY6,P21796,O15269,Q9NQ88,P05141,Q16543,P12235 10 +Embryonic axis specification 0.6345223375891731 1.3629904515893234 0.1728855199054852 1.0 0.6496596242773319 6 Q15363,Q8N2A8 2 +Negative regulation of regulated secretory pathway 0.6343030195026257 1.36192650578662 0.17322108027057 1.0 0.650271144371883 6 P09601 1 +Entry of bacterium into host cell 0.6778182176613915 1.3605248106830494 0.1736639070348673 1.0 0.6511901462761246 5 Q9BTY2,Q9UPT5 2 +Cell recognition 0.396782758546012 1.3595776975237606 0.1739635997151831 1.0 0.6512915872931732 25 P15291,P45880,Q5KU26,Q8WTV0,Q9NQC3,P05067,P35613,Q14157 8 +Glycerophospholipid biosynthetic process 0.3794635755034553 1.3569593873450203 0.1747941152138583 1.0 0.6538028516107146 47 Q96N66,Q9NX62,Q9NPH0,Q9NTJ5,Q92643,Q10713,O14735,Q8TBX8,Q8NF37,Q9HCL2,Q5H8A4,Q9BTU6,O43292,Q9UG56,Q9HBU6,Q9NUQ2,Q9H490 17 +Regulation of phospholipid transport 0.7242223764204528 1.3541435306905438 0.1756905906178367 1.0 0.6541769459369587 4 Q9Y255,Q9NV96 2 +Mitochondrial adp transmembrane transport 0.8750705019740528 1.3524630931262915 0.1762272176489787 1.0 0.6548387136621123 3 P12236,P12235 2 +Nucleobase transport 0.8750705019740492 1.3524630931262784 0.1762272176489829 1.0 0.6548387136621123 3 Q9Y277,P12235 2 +Protein targeting to membrane 0.373349889168742 1.3502994622922613 0.1769199447727134 1.0 0.6559096450177683 42 Q9UHB9,Q9Y3D6,P43307,O00560,Q15629,P46379,O60725,P27105,P40855 9 +Pigment granule organization 0.5537151419577935 1.349948149418117 0.1770326153946078 1.0 0.6559096450177683 8 Q13637,O95295,Q9NP58,Q9BXS5 4 +Cell death in response to oxidative stress 0.3948266043182279 1.3415491897340013 0.17974221029759 1.0 0.6600583568549693 25 Q9NR28,Q969S3,P04062,Q99720,Q15118,Q07820 6 +Protein maturation by protein folding 0.6293034295656234 1.3376616920723057 0.1810067440196099 1.0 0.6623314958953784 6 P62942 1 +Excretion 0.6725564625717514 1.3365540186802505 0.1813682566683254 1.0 0.6623314958953784 5 P09601 1 +Receptor catabolic process 0.5408105961876574 1.3352126706770495 0.1818067510112286 1.0 0.662897665629776 10 Q9Y371,P46934 2 +Intermediate filament bundle assembly 0.8695410484566097 1.33080272344724 0.1832539315970887 1.0 0.6653697600444834 3 P07197 1 +Membrane biogenesis 0.3934518819432422 1.328871914690805 0.1838902310930124 1.0 0.6658698765194168 25 Q9HD42,Q96CP7,Q12846,Q6NUK4,Q86XL3,Q16739,Q9Y3E7,Q9H6H4,O75955 9 +Intracellular distribution of mitochondria 0.8615731604172574 1.328707790131364 0.1839443938244787 1.0 0.6658698765194168 2 O75153 1 +Response to mitochondrial depolarisation 0.5498827274876673 1.3285321879842724 0.1840023573544384 1.0 0.6658698765194168 8 P52789,P04062,Q16543 3 +Cdp diacylglycerol metabolic process 0.5413942937931779 1.3282858216105586 0.1840837018493155 1.0 0.6658698765194168 9 O14735,Q9HCL2,Q86UL3,Q9NUQ2,O95674 5 +Triglyceride metabolic process 0.4677257958553561 1.327102702047161 0.1844747116370451 1.0 0.6662768689933255 14 Q96N66,Q92604,Q9HCL2,P50416,Q8NCG7,Q8WTV0,Q9UBV2 7 +Endosomal lumen acidification 0.8607273752466873 1.3251836337549507 0.1851102522499867 1.0 0.667838798161362 2 Q9P0T7 1 +Chemical homeostasis within a tissue 0.8601635184663143 1.3228343916745535 0.1858904574201569 1.0 0.6695517735226574 2 Q8NF37 1 +Positive regulation of peptidase activity 0.3752477559880146 1.3224131020831411 0.1860306283110966 1.0 0.6696898973191475 46 Q92542,Q9NR28,O14737,Q96A26,Q9Y3D6,Q96HY6,Q9NZJ7,Q9UL46,Q9Y255,Q9P0J0,P61289,P05067,P51572,Q99538 14 +Vesicle targeting to from or within golgi 0.4667316454486039 1.320232691100698 0.1867573403896996 1.0 0.6707895695711279 14 Q8N6H7,O15027,Q92734,P49755,Q92538,Q9NR31,Q15363,O00743 8 +Lipid phosphorylation 0.8593177332957441 1.319310829660725 0.1870652187756258 1.0 0.6707895695711279 2 Q53H12 1 +Negative regulation of secretion 0.4310498756888 1.3183752906542008 0.1873780481795006 1.0 0.6707895695711279 20 Q16850,Q16836,P09601,Q8N5M9,Q06787 5 +Nad biosynthesis via nicotinamide riboside salvage pathway 0.859035804905555 1.318136390862691 0.1874579943548324 1.0 0.6707895695711279 2 P43490 1 +Diet induced thermogenesis 0.8579080913447876 1.313439055615982 0.189035044385222 1.0 0.6753305197835986 2 Q96E52 1 +Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation 0.8573442345644237 1.3110906455450464 0.1898271407893932 1.0 0.6759572847708929 2 Q15363 1 +Regulation of translation initiation in response to endoplasmic reticulum stress 0.8573442345644237 1.3110906455450464 0.1898271407893932 1.0 0.6759572847708929 2 Q15363 1 +Negative regulation of nervous system development 0.4353755822328093 1.306967593132485 0.1912237178708062 1.0 0.6787679288710221 19 Q15154,Q96G23,P30536,Q9NQC3,Q06481,Q8N0X7 6 +Positive regulation of protein neddylation 0.8562165210036535 1.3063943565627254 0.1914184840124517 1.0 0.6787679288710221 2 Q9BTE7 1 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4647275864304405 1.306378930565126 0.1914237272536585 1.0 0.6787679288710221 14 Q9NR28,Q96A26 2 +Cell proliferation in forebrain 0.6657412986588532 1.3054849617352218 0.1917277645732074 1.0 0.6787679288710221 5 Q15154,Q15058 2 +Regulation of endothelial cell migration 0.3831659413681623 1.3053762446073418 0.1917647632988426 1.0 0.6787679288710221 30 P57105,P09601,Q8WTV0,P23634,P06576,P42785 6 +Myelin assembly 0.5753539858844041 1.302700771468898 0.1926769385736886 1.0 0.6800395438753157 7 Q16880 1 +Negative regulation of low density lipoprotein receptor activity 0.8550888074429128 1.3016987973670082 0.1930193708730558 1.0 0.6806908322960259 2 P05067 1 +Protein peptidyl prolyl isomerization 0.3826785605510496 1.300622937044846 0.1933875519226517 1.0 0.6812586657714412 30 Q9Y680,P26885,Q96AY3,Q9NWM8,O95302,P62942 6 +Neuron maturation 0.5745194147619422 1.2982978894512256 0.1941849913733158 1.0 0.6822407522768685 7 O75503,Q9NZJ7 2 +Positive regulation of lipid catabolic process 0.664064525257104 1.2978377599227582 0.1943430912000239 1.0 0.6824316662159943 5 P33897,Q8NCG7 2 +Phospholipid homeostasis 0.8604060913705522 1.295030095003988 0.1953098478739341 1.0 0.6829095531455953 3 Q9HCL2,Q96CP7 2 +Protein localization to membrane raft 0.6628967554493724 1.2925113317062769 0.1961801242207941 1.0 0.6834092568856796 5 Q9BRK0,P05026,O75955 3 +Nerve development 0.5727902172496475 1.2891735033618883 0.1973377744456195 1.0 0.6850612225027645 7 Q9H061 1 +Positive regulation of blood circulation 0.6620024567604103 1.2884319370246704 0.1975956474049187 1.0 0.6850612225027645 5 P09493,P16615 2 +Odontogenesis of dentin containing tooth 0.5341840571663401 1.2870371485429504 0.1980813403534678 1.0 0.6860352688282032 9 Q13586,P35613 2 +Maintenance of blood brain barrier 0.5421726896361132 1.2854001595933555 0.1986524854770954 1.0 0.6870671074705444 8 Q16625,Q07157,Q9UDY2,Q9BX67,P55011 5 +Lipid homeostasis 0.3771251956488285 1.2846872590935496 0.1989015923101591 1.0 0.6870671074705444 32 Q9BWH2,O15260,P33897,Q96CP7,O15118,Q9HCL2,Q15067,Q86YV9,Q99758,Q8WTV0,Q9NQC3,Q9NP80,Q9Y6C9 13 +Cobalamin transport 0.8502960248096854 1.2817514232379217 0.199929859599705 1.0 0.6891712193853562 2 P33527 1 +Antigen processing and presentation of exogenous antigen 0.5328873738026548 1.2796135627276586 0.2006810775264154 1.0 0.6906747498122627 9 P50570,Q03518,P04439,Q9UIQ6,Q99538 5 +Biomineralization 0.4406731969800017 1.2751597478307948 0.2022527052439522 1.0 0.6925272830219305 17 O75844,Q6P4Q7,Q13586,P20020,Q8N5W9 5 +Regulation of endoplasmic reticulum unfolded protein response 0.5700118179941618 1.27450808709722 0.2024834084308411 1.0 0.6927631163358071 7 P57088,Q92905,Q96HY6,O76024 4 +Collateral sprouting 0.7048748370354119 1.270565416883186 0.2038832966206092 1.0 0.6947877937169673 4 P05067,Q8N0X7 2 +Intermediate filament organization 0.6152148295837956 1.2691889506528042 0.2043736809631173 1.0 0.6950184589940139 6 P08670,P07197 2 +Potassium ion homeostasis 0.6568848758464932 1.2650831712489194 0.2058415148476462 1.0 0.6978393682072177 5 P54709,P05023,P05026,P55011 4 +Positive regulation of glycoprotein metabolic process 0.5680626976486043 1.264216702934848 0.2061522573104304 1.0 0.6978393682072177 7 Q92542,Q9H0U4 2 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4583742674763052 1.2624213560565871 0.2067972085855216 1.0 0.6978393682072177 14 Q07021,O43657,Q86UT6,Q99623 4 +Negative regulation of neuron death 0.3674240565947693 1.2609837180883532 0.2073147133843875 1.0 0.6978393682072177 44 P07196,Q01105,P09601,P04062,P50897,O76024,Q4ZIN3 7 +Cell volume homeostasis 0.5669135281244131 1.25814793466624 0.2083382603852439 1.0 0.6994592846114086 7 P51797,Q9NUT2,P51790 3 +Outer mitochondrial membrane organization 0.6548365725244334 1.255736068228552 0.2092116776189758 1.0 0.7020332671938797 5 Q9NS69 1 +Organelle transport along microtubule 0.3716783685560627 1.2512741441250372 0.2108344753951467 1.0 0.7028172045990271 33 Q8WXH0,P07196,O95295,O75381,Q5SNT2,Q8TD16,Q9Y2T2,P62820,O60313,P78537,P11279,Q9UBK9 12 +Protein processing 0.3755173846832776 1.25055660096048 0.211096292747001 1.0 0.7033334941221002 53 P67812,O75787,Q96TA2,Q8TAD4,Q15392,Q96E52,Q9H9S5,O75976,Q92896,Q15005,O75503,Q99538,Q9UG56,Q9UJZ1,Q9H300,P42892,Q92542,Q9Y366,O75844,Q10713,Q969M3,Q2T9J0 22 +Suckling behavior 0.848783922217808 1.249553144037497 0.2114628285917379 1.0 0.7037011816281681 3 Q9GZP9 1 +Negative regulation of immune effector process 0.4863989679096508 1.2455410947117838 0.2129329195533844 1.0 0.7044155138313198 12 Q08722,P46108,P09601,P01889,P04439,Q96FV9 6 +Cardiac ventricle development 0.4275037864943443 1.2453591941593607 0.2129997457881502 1.0 0.7044155138313198 19 O75844,Q15643,Q6PI78,P09493,O96028,P62942 6 +Amino acid import across plasma membrane 0.6523702031602524 1.244480205452497 0.213322880139589 1.0 0.7044155138313198 5 O75915,Q15758,P08195,P30825 4 +Positive regulation of t cell proliferation 0.506010997559223 1.2443013561430576 0.2133886721260758 1.0 0.7044155138313198 11 P02786,P30825,P04439,Q9HCL2 4 +Regulation of nervous system process 0.4861951334903001 1.2442427098294986 0.2134102491042193 1.0 0.7044155138313198 12 P05067,P04062,O75746 3 +Positive regulation of release of cytochrome c from mitochondria 0.6090457743596729 1.2391737256466986 0.2152811685973208 1.0 0.7063867019025881 6 O14737,Q96A26 2 +Positive regulation of nucleotide metabolic process 0.6089765363650341 1.2388367739388009 0.2154059522258231 1.0 0.7063867019025881 6 O75746,P00403 2 +Polyol biosynthetic process 0.4485166244901608 1.2351885665026023 0.2167603334675003 1.0 0.7081928684701772 15 P00374,O15269,P04062,Q13510 4 +Nucleus localization 0.4543954578788304 1.2348683104309093 0.2168795190657781 1.0 0.7081928684701772 14 Q8WXH0,Q15154,Q5SNT2,Q9UH99,Q14203,P42345 6 +Developmental pigmentation 0.5234048454991145 1.2343805782323187 0.2170611226812806 1.0 0.7081928684701772 10 Q9BXS5,P22413,O75787,Q86YV9 4 +Regulation of bone mineralization 0.5622833746183608 1.233688592458272 0.2173189663269155 1.0 0.7081928684701772 7 O75844,Q8N5W9,P20020 3 +Regulation of reactive oxygen species metabolic process 0.3628477411917616 1.2326079512377195 0.2177220689628165 1.0 0.7081928684701772 36 P33897,Q9BSK2,P52789,P30536,P00403,P51790,Q9NRA0,Q9H300,P00374,P42785 10 +Insulin secretion involved in cellular response to glucose stimulus 0.5614194482655946 1.2291236349329444 0.2190254549062014 1.0 0.7081928684701772 7 O95563,Q12846,Q8N5M9 3 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.5614194482655946 1.2291236349329444 0.2190254549062014 1.0 0.7081928684701772 7 O95563,Q12846,Q8N5M9 3 +Xenobiotic transmembrane transport 0.8430453839292718 1.2271198865007702 0.2197775344722672 1.0 0.7081928684701772 3 Q9NV96 1 +Disaccharide metabolic process 0.8370453904708044 1.226691114244156 0.2199387087105899 1.0 0.7081928684701772 2 P10253 1 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5609323915439692 1.2265499035913334 0.2199918079433116 1.0 0.7081928684701772 7 P52789,P04062,Q16543 3 +Positive regulation of cysteine type endopeptidase activity 0.3712884446936698 1.226301829469497 0.2200851131605723 1.0 0.7081928684701772 32 Q9NR28,O14737,Q96A26,Q9Y3D6,Q9NZJ7,Q9P0J0,P51572,Q99538 8 +Determination of adult lifespan 0.5235760635220361 1.2262675641425096 0.2200980032085169 1.0 0.7081928684701772 9 O75844 1 +Regulation of blood circulation 0.3794853610896786 1.2232552658151288 0.2212332975237663 1.0 0.7103100039780679 27 O75844,P16615,P10253,P20020,Q9HD47,P23634,P09493,P42892 8 +Regulation of steroid biosynthetic process 0.523024308919525 1.223104757383687 0.2212901319980327 1.0 0.7103100039780679 9 P16435,P30536,Q13510,O94905,P05023 5 +Isotype switching to iga isotypes 0.8411462152699866 1.2196994515421062 0.2225788295922486 1.0 0.7127073818053646 3 O96028 1 +Regulation of protein secretion 0.3600768836720543 1.2191296424544518 0.2227949907231579 1.0 0.7130523863679851 41 Q16822,Q16836,Q5T9L3,Q16850,Q12846,Q8N183,Q9H4A6,O95563,Q32P28,P53985,P49755,P04035,Q8N5M9,O00429,P50416,Q96KC8,P55011 17 +Phosphatidylglycerol acyl chain remodeling 0.8350718917395005 1.2185037320890089 0.2230326073994284 1.0 0.713465690109942 2 Q8NF37 1 +Heart process 0.3703838201260141 1.2172449740405926 0.22351102335179 1.0 0.7146485175424032 32 O75844,P16615,P10253,Q96PU5,O00429,P20020,Q9HD47,P23634,P09493,P42345 10 +Positive regulation of leukocyte degranulation 0.6044246681432214 1.2166819649196057 0.2237252435478107 1.0 0.71498587308744 6 Q9NRA0,P11279 2 +Positive regulation of interleukin 1 production 0.51996294652771 1.2144151791703153 0.2245892219073546 1.0 0.7173984033436968 10 P05067,Q99584,Q96RD7 3 +Amine transport 0.6031611628563354 1.210531453250795 0.226075029046918 1.0 0.717960147774785 6 Q15042,Q7L0J3,O75915,P05556,P55011 5 +Establishment of protein localization to endoplasmic reticulum 0.3883495198021195 1.2062369585426969 0.2277261372627683 1.0 0.7213499913698987 24 Q9UHB9,P61026,P49458,Q15005,O43681,Q9Y5M8,Q15629,P46379 8 +Learning 0.417073905490316 1.206044048713465 0.2278005066254036 1.0 0.7213499913698987 20 P05067,O00264,P50897,P04035 4 +Electron transport chain 0.3836291025968519 1.205298591616064 0.2280880531223057 1.0 0.7219129573558252 72 O95139,Q9H3K2,Q9UDW1,P16435,O75746,O75208,O14548,P04062,O14949,P00403,P03886,Q9P0J0,P13073,Q7KZN9,Q16134,O43676,O96000 17 +Mitochondrial protein catabolic process 0.8316887510572322 1.2044772828802028 0.2284051572748084 1.0 0.7225688885985644 2 Q96TA2 1 +Ether biosynthetic process 0.6427765237020246 1.2006930556809898 0.2298702888639527 1.0 0.7258074363217559 5 O15228,Q6IAN0,P49327,Q8WVX9 4 +Apoptotic cell clearance 0.4983062713381366 1.197522668558998 0.2311028974177627 1.0 0.727063599045035 11 P06756,Q07954,P04083,Q8WTV0,Q08431 5 +Fat soluble vitamin metabolic process 0.6004088796461511 1.197133084287741 0.2312546864829008 1.0 0.727063599045035 6 Q8N0U8,P04062,P38435,Q99538 4 +Blood vessel endothelial cell migration 0.3949923678172645 1.196353262056254 0.2315587320349348 1.0 0.727063599045035 23 P09601,Q8WTV0,P23634,P06576,P42785 5 +Collateral sprouting in absence of injury 0.8294333239357192 1.195133025589121 0.232035060555527 1.0 0.727063599045035 2 P05067 1 +Regulation of lipase activity 0.4637420228165798 1.194179695264229 0.2324076839387903 1.0 0.727063599045035 13 P16435,Q99623,Q07954,P40616,P50897 5 +Regulation of cellular response to osmotic stress 0.8338738791742618 1.1913054423929688 0.2335336981433484 1.0 0.727063599045035 3 O95202 1 +Cellular response to insulin like growth factor stimulus 0.6865266268841989 1.191292476893996 0.2335387862406324 1.0 0.727063599045035 4 P46108,Q9BSK2 2 +Bone development 0.3730437881097375 1.1902780238171895 0.2339371353638184 1.0 0.727063599045035 29 O75844,Q92896,Q9NX62,P16435,Q32P28,Q15125,Q15904,O96028,Q8N5W9,Q7RTS9 10 +Negative regulation of cellular amine metabolic process 0.8280236819847802 1.1892957237197936 0.2343233175030243 1.0 0.7276413877324794 2 P23634 1 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5168407980863646 1.1876506126895474 0.2349710887464418 1.0 0.7286208631236905 9 Q07021,O43657,Q86UT6 3 +Pyridine nucleotide biosynthetic process 0.832471662205708 1.1858347497100394 0.2356875654354953 1.0 0.7300844090353166 3 P43490 1 +Neurofilament cytoskeleton organization 0.8271778968142082 1.1857944302184709 0.2357034916353111 1.0 0.7300844090353166 2 P07196 1 +Positive regulation of nervous system process 0.6847710589229199 1.183711584147592 0.2365272517932117 1.0 0.7308876242739849 4 P04062 1 +Regulation of regulated secretory pathway 0.3935242855187131 1.1835503272019747 0.2365911132855882 1.0 0.7308876242739849 23 Q12846,P16615,P09601,P11279,Q9NRA0,Q06787 6 +Cellular potassium ion homeostasis 0.6843441466854836 1.1818682663311284 0.2372579752559291 1.0 0.7322598325942028 4 P05026,P05023,P55011 3 +Vacuolar proton transporting v type atpase complex assembly 0.8260501832534353 1.181127336083525 0.237552141957078 1.0 0.7328238450523934 2 Q8N511 1 +Action potential 0.4131700481334811 1.174624520495316 0.2401449688092263 1.0 0.7365598788212021 20 P16615,Q96PU5,P04062,Q9HD47,Q06787,P42345,P05023,P62258 8 +Detection of other organism 0.8243586129123252 1.1741295409449288 0.2403431426036775 1.0 0.7365598788212021 2 P04439 1 +Protection from natural killer cell mediated cytotoxicity 0.8243586129123252 1.1741295409449288 0.2403431426036775 1.0 0.7365598788212021 2 P04439 1 +Regulation of lymphocyte mediated immunity 0.4063718790597032 1.1721473339864887 0.2411379087697422 1.0 0.7365598788212021 21 P46108,P01889,P04439,P11279,Q9NUQ9,O96028,O15400,Q96FV9 8 +Hormone biosynthetic process 0.5141344039817071 1.1721297511989426 0.2411449668613823 1.0 0.7365598788212021 9 P16435,Q53GQ0,P30536,Q14849,P05023 5 +Neuron cellular homeostasis 0.5505533683119325 1.171687917999381 0.2413223755287381 1.0 0.7365598788212021 7 P20020,P23634,P51790 3 +Regulation of pattern recognition receptor signaling pathway 0.3920862480510412 1.1710077207400118 0.2415956737654214 1.0 0.7365598788212021 23 O43657,Q9NPR9,Q86UT6,Q9NQC3,Q07021,Q06481,O75955 7 +Xenobiotic export 0.8229489709613783 1.168300724735403 0.2426854831386955 1.0 0.7375889198721834 2 Q99758 1 +Xenobiotic transport across blood brain barrier 0.8229489709613598 1.168300724735326 0.2426854831387266 1.0 0.7375889198721834 2 P33527 1 +Sphingolipid translocation 0.8229489709613598 1.168300724735326 0.2426854831387266 1.0 0.7375889198721834 2 P33527 1 +Acylglycerol homeostasis 0.6354463333772356 1.1672419201819242 0.2431126862217518 1.0 0.7383217392178193 5 Q9BWH2,Q8WTV0 2 +Pigment granule localization 0.6351739332202138 1.1659990611901905 0.2436148250486847 1.0 0.7387914640044981 5 P62820,Q9H267,Q13561 3 +Proton transporting v type atpase complex assembly 0.8262831359277968 1.1617083882024937 0.2453539372733406 1.0 0.7415117908798214 3 Q8N511,Q9P0T7 2 +Reactive oxygen species metabolic process 0.3644172147099799 1.158968316074635 0.2464691001300591 1.0 0.7425686081334857 50 P33897,Q9BSK2,P52789,P30536,P00403,Q15067,Q13423,P51790,Q9P0J0,O75027,Q9NRA0,Q9H300,Q9UII2,P00374,P42785 15 +Negative regulation of cell development 0.3748636516080965 1.1570189210421995 0.2472646300469096 1.0 0.7435619083274702 25 Q15154,O43707,Q96G23,P30536,Q9NQC3,Q06481,Q8N5W9,Q8N0X7 8 +Regulation of mitochondrial gene expression 0.4725067603273257 1.1570017219983662 0.2472716568088691 1.0 0.7435619083274702 12 Q9Y2R0,Q9NWS8,Q567V2 3 +Neurotransmitter transport 0.369453018955705 1.1555545502359947 0.2478634075700503 1.0 0.7435619083274702 29 Q7L0J3,Q12846,Q9H2J7,P16615,P50897,Q06787,O95721,Q96QD8,O75955 9 +Negative regulation of natural killer cell mediated immunity 0.8245910885504819 1.1551173010750817 0.2480423942329912 1.0 0.7435619083274702 3 P46108,P04439 2 +Detection of external biotic stimulus 0.824591088550478 1.155117301075068 0.2480423942329968 1.0 0.7435619083274702 3 P04439,Q8WTV0 2 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8245910885504737 1.1551173010750495 0.2480423942330043 1.0 0.7435619083274702 3 P10321,P04439 2 +Regulation of nitric oxide synthase activity 0.5916210162007596 1.1543521627093825 0.2483558189495402 1.0 0.7439232346914121 6 P06280,P00374,Q8WTV0 3 +Transmission of nerve impulse 0.518456154684444 1.1524767665356976 0.2491252116022422 1.0 0.7444610481938604 8 P04062,Q06787 2 +Regulation of phospholipase activity 0.5089429744728099 1.150468552395734 0.2499509394011219 1.0 0.7446373192941744 10 P40616,P50897,Q07954,Q99623 4 +Aspartate transmembrane transport 0.6317682931237756 1.1504624168990605 0.2499534650910493 1.0 0.7446373192941744 5 Q9UJS0,O75746 2 +Negative regulation of growth 0.3594500459418513 1.148577265581582 0.2507303359512201 1.0 0.7446373192941744 34 P30153,Q9P0J0,P50897,O14681,P22413,Q9NRA0,Q9NQC3,Q8N0X7,Q99538 9 +Regulation of anion transmembrane transport 0.590201644878974 1.1474432202484786 0.2511984871720905 1.0 0.7446373192941744 6 O75915,P05556,P08183 3 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.5459414785820539 1.1473062891996524 0.2512550556407755 1.0 0.7446373192941744 7 P14635,Q9Y6D9,Q9Y6G9,P12270 4 +Negative regulation of exocytosis 0.5097304745605441 1.1468725417495524 0.2514343025145602 1.0 0.7446373192941744 9 P09601 1 +Aerobic respiration 0.3815097939865903 1.1468296030682514 0.2514520518493386 1.0 0.7446373192941744 92 Q9UDW1,P33897,O14949,Q15070,P00846,O43676,O95139,P56385,O14548,O75964,P00403,P21912,Q9H3K2,O75208,P03886,Q13423,P13073,P14406,O96000,Q9BSK2,Q7KZN9,P24539 22 +Cell migration involved in sprouting angiogenesis 0.5458485711880323 1.146815132972149 0.2514580334730669 1.0 0.7446373192941744 7 P09601,Q5JRA6 2 +Positive regulation of response to endoplasmic reticulum stress 0.5456924239757474 1.1459896612397282 0.2517994299353845 1.0 0.7450118492869099 7 P51572,Q4ZIN3,P46379 3 +Response to ph 0.5897620205456099 1.1453033921993074 0.2520835012769864 1.0 0.7454825485156203 6 P04062,P51798,Q99538 3 +Cerebral cortex radially oriented cell migration 0.5454506643928831 1.1447116069055618 0.2523286417620163 1.0 0.7455146919118714 7 Q8WXH0,Q96N66,Q9NQC3 3 +Telencephalon glial cell migration 0.5454506643928831 1.1447116069055618 0.2523286417620163 1.0 0.7455146919118714 7 Q8WXH0,Q96N66,Q9NQC3 3 +Regulation of lipid metabolic process 0.3727265940898489 1.1416026354796964 0.2536192280595133 1.0 0.7461405029391893 62 P33897,Q96G23,Q9NZJ7,Q9H2C2,Q8NF37,Q13510,Q15118,Q8WTV0,Q8NBJ4,P07602,Q99623,Q92604,P50416,Q9UJZ1,P42345,O75844,Q96N66,P16435,Q8TBX8,P30536,Q99758,Q8NCG7,Q9NRA0,Q2T9J0,Q06481,Q9H6K4 26 +Zinc ion homeostasis 0.6749674361267175 1.1414029020471297 0.2537022975923975 1.0 0.7461405029391893 4 Q8TAD4 1 +Toll like receptor 3 signaling pathway 0.6748562073501354 1.140923178418319 0.2539018929834771 1.0 0.7461405029391893 4 Q5KU26 1 +Positive regulation of potassium ion transmembrane transporter activity 0.6747531734837756 1.1404788058342945 0.2540868775942972 1.0 0.7461405029391893 4 P50570,P54709,P05026 3 +Regulation of protein catabolic process in the vacuole 0.6293819637474156 1.139578491542708 0.2544619503089067 1.0 0.7461405029391893 5 P98164,P04062 2 +Regulation of lysosomal protein catabolic process 0.6293819637474156 1.139578491542708 0.2544619503089067 1.0 0.7461405029391893 5 P98164,P04062 2 +Collagen fibril organization 0.488596653274289 1.138548395134127 0.2548915627806956 1.0 0.7461405029391893 11 Q04656,Q92791,O75718,Q96AY3,P13674 5 +Negative regulation of muscle adaptation 0.8156188328164702 1.1380327678434043 0.2551067998624376 1.0 0.7461405029391893 2 P23634 1 +Regulation of cardiac muscle adaptation 0.8156188328164702 1.1380327678434043 0.2551067998624376 1.0 0.7461405029391893 2 P23634 1 +Negative regulation of cardiac muscle adaptation 0.8156188328164702 1.1380327678434043 0.2551067998624376 1.0 0.7461405029391893 2 P23634 1 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5879311082996539 1.136392149946629 0.2557924796989073 1.0 0.7470457988364624 6 Q07021,O43657 2 +Melanosome assembly 0.8150549760360855 1.1357075392780496 0.2560789842261579 1.0 0.7473557433070219 2 Q13637 1 +Regulation of cation transmembrane transport 0.3632634516036212 1.1355955556412904 0.2561258697603812 1.0 0.7473557433070219 51 P46934,O43707,Q13586,Q96PU5,Q9HD47,P27105,Q06787,P21796,P05067,P23634,Q9NRA0,Q8TAD4,P62942 13 +Response to retinoic acid 0.4690221913620004 1.1347881965283289 0.2564640729691461 1.0 0.7480107352186579 12 P02786,Q9P0J0,Q8TB36,Q99623 4 +Protein localization to endoplasmic reticulum exit site 0.6730606488011341 1.133180118340119 0.2571386215624995 1.0 0.7487976460704808 4 P51572,Q5JRA6,Q92538 3 +Phagosome maturation 0.6278067746604943 1.132395515079624 0.257468189568832 1.0 0.7487976460704808 5 Q13637,Q9BZG1,P61106 3 +Neural precursor cell proliferation 0.3669737496039527 1.1315729749743628 0.2578140072597867 1.0 0.7487976460704808 29 Q15154,P61026,O15031,P55209,P98164,Q8NCG7,Q06481 7 +Actin filament based movement 0.3684292496876638 1.1314446319237954 0.2578679951260705 1.0 0.7487976460704808 28 Q8WXH0,O43707,P16615,Q9UH99,Q96PU5,Q9HD47,Q9UM22,P09493 8 +Midbrain development 0.4173192911419787 1.1299864921928593 0.2584819163230754 1.0 0.7487976460704808 18 O14949,P24539 2 +Pirna metabolic process 0.8136453340851451 1.1298964957645412 0.2585198407244906 1.0 0.7487976460704808 2 Q8N2A8 1 +Aminophospholipid transport 0.818088522562954 1.1298119079270734 0.2585554894672437 1.0 0.7487976460704808 3 Q14108 1 +Cellular response to nutrient 0.6266510082769029 1.127125910111875 0.2596892499573053 1.0 0.7493616102111933 5 P20020,P09601 2 +Ether metabolic process 0.5062639315992266 1.126992661037166 0.2597455839116438 1.0 0.7493616102111933 9 O15228,Q6IAN0,Q8WVX9,Q6PIU2,P49327,P07099,P34913 7 +Negative regulation of gliogenesis 0.6265870309949012 1.1268342320454936 0.2598125742349375 1.0 0.7493616102111933 5 Q96G23 1 +Magnesium ion transport 0.8172758338833026 1.126652128486862 0.259889589918159 1.0 0.7493616102111933 3 Q8N4V1 1 +Negative regulation of receptor binding 0.8122356921342024 1.1240884051537814 0.2609755236838618 1.0 0.750623268376919 2 P16615 1 +Leukotriene transport 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.750623268376919 2 P33527 1 +Tripeptide transport 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.750623268376919 2 P33527 1 +Tripeptide transmembrane transport 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.750623268376919 2 P33527 1 +Oligopeptide transport 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.750623268376919 2 P33527 1 +Muscle hypertrophy in response to stress 0.8158488437676195 1.1211055514637955 0.2622429359199736 1.0 0.7511633395425852 3 P23634,P16615 2 +Regulation of water loss via skin 0.6702128639495085 1.1209039575178774 0.2623287461579897 1.0 0.7511633395425852 4 P04062 1 +Regulation of steroid hormone biosynthetic process 0.8113899069636334 1.1206049974764736 0.2624560368357702 1.0 0.7511633395425852 2 P16435 1 +Regulation of hormone biosynthetic process 0.8113899069636334 1.1206049974764736 0.2624560368357702 1.0 0.7511633395425852 2 P16435 1 +Iron coordination entity transport 0.81528482797518 1.118913862066037 0.2631768885938506 1.0 0.752173026049038 3 O75027,O15173 2 +Heme transport 0.81528482797518 1.118913862066037 0.2631768885938506 1.0 0.752173026049038 3 O75027,O15173 2 +Mitochondrial proton transporting atp synthase complex assembly 0.8152604330367992 1.1188190742251305 0.2632173326100284 1.0 0.752173026049038 3 Q15070 1 +Fatty acid elongation 0.8150028200789615 1.1178181439587416 0.263644670715089 1.0 0.752173026049038 3 Q9P035,P33897 2 +N glycan processing 0.624515021626124 1.1173889719511 0.2638280483456605 1.0 0.752173026049038 5 O60476,Q16706,P14314 3 +Meiotic chromosome segregation 0.3705523000637116 1.1170979142206343 0.2639524622352409 1.0 0.752173026049038 25 P30153,Q92791,Q9BXW9,P46379,Q9BTX1,Q9BZD4,Q96KQ7,O94901,P53350 9 +Dna methylation involved in gamete generation 0.8138747884940754 1.11343612616024 0.265521166688381 1.0 0.7543553837189987 3 Q8NB78,Q8N2A8 2 +Regulation of metal ion transport 0.3658603632361951 1.1058892640102855 0.2687744522103701 1.0 0.7582056076039262 57 P46934,Q13586,Q96PU5,P30536,P20020,Q9HD47,P27105,Q06787,O76024,P21796,P23634,Q9NRA0,P62942 13 +Very long chain fatty acid metabolic process 0.4504314965522258 1.1058013333018908 0.268812517804573 1.0 0.7582056076039262 13 Q9P035,P33897,Q15067,O14678,Q9UKU0 5 +Motor neuron apoptotic process 0.8074429095009854 1.104363939855449 0.2694352966641817 1.0 0.7582056076039262 2 O75312 1 +Regulation of calcium ion transport 0.3571949300721502 1.1043585478631757 0.2694376347129212 1.0 0.7582056076039262 33 Q13586,P30536,P20020,Q06787,P21796,O76024,P62942 7 +Vesicle cargo loading 0.435395686599905 1.103184498107736 0.2699470518751437 1.0 0.7582056076039262 14 Q96PC5,Q5JRA6,P49755,Q9NR31,Q15363 5 +Intermediate filament based process 0.4826430690438414 1.1023946461268672 0.2702901380981852 1.0 0.7582056076039262 11 P08670,P07196,P07197,Q16352 4 +Negative regulation of cation channel activity 0.5809387282022398 1.1023706674244602 0.2703005583470879 1.0 0.7582056076039262 6 P62942 1 +Response to estrogen 0.449862836918006 1.102026600642675 0.2704501072584477 1.0 0.7582056076039262 13 P09601 1 +Positive regulation of autophagy of mitochondrion 0.5372643291031605 1.1014437489363949 0.2707035736517738 1.0 0.7585928435908462 7 P27544,P12235,P21796 3 +Diacylglycerol metabolic process 0.8103940834096134 1.0999236636598904 0.2713653833649552 1.0 0.7593681089761588 3 Q9HCL2 1 +Protein o linked glycosylation via threonine 0.8093311798641973 1.0958001318031882 0.2731662508095243 1.0 0.7616000133845872 3 Q8N4A0 1 +Regulation of nucleotide biosynthetic process 0.5002695417899335 1.092625371010816 0.2745583185795144 1.0 0.7620572387439386 9 Q15118,O75746,P00403 3 +Steroid catabolic process 0.6625608465654893 1.0879491811344502 0.2766175427518393 1.0 0.7637756417627403 4 Q8WTV0 1 +Negative regulation of collateral sprouting 0.8026501268677767 1.0846772669586904 0.2780646198184426 1.0 0.7638084864799611 2 Q8N0X7 1 +Branching morphogenesis of a nerve 0.8026501268677585 1.0846772669586155 0.2780646198184757 1.0 0.7638084864799611 2 Q9NQC3 1 +Negative regulation of synapse organization 0.8026501268677579 1.0846772669586136 0.2780646198184766 1.0 0.7638084864799611 2 O00264 1 +Regulation of heart contraction 0.3668605420152661 1.0829164062805268 0.2788455290080469 1.0 0.7638084864799611 25 O75844,P16615,P10253,Q6PI78,P20020,Q9HD47,P23634,P09493,P05023,P62258 10 +Negative regulation of glucose import 0.661362041767699 1.0827910075285034 0.2789011978860949 1.0 0.7638084864799611 4 Q06481 1 +Negative regulation of cell growth 0.3569440290858394 1.082553380271013 0.2790067096453696 1.0 0.7638084864799611 32 P30153,Q9P0J0,O14681,P50897,P22413,Q9NRA0,Q9NQC3,Q8N0X7 8 +L aspartate transmembrane transport 0.6612630951651175 1.082365325735101 0.2790902292614645 1.0 0.7638084864799611 4 Q9UJS0,O75746 2 +Bone mineralization 0.4968511813789998 1.0803214116464244 0.2799990781633203 1.0 0.7638084864799611 10 O75844,Q8N5W9,P20020 3 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.4789643125013083 1.0800645510970124 0.280113436124322 1.0 0.7638084864799611 11 P35613 1 +Positive regulation of granulocyte chemotaxis 0.616078116256165 1.0789582483951266 0.2806063404353898 1.0 0.7644964278979411 5 Q07021,O00429 2 +Positive regulation of neutrophil migration 0.616078116256165 1.0789582483951266 0.2806063404353898 1.0 0.7644964278979411 5 Q07021,O00429 2 +Positive regulation of cell growth 0.3432244760617093 1.0769487061566425 0.2815031818562521 1.0 0.7644964278979411 38 P51812,Q9GZP9,Q9BSK2,Q96PU5,O95684,Q15418 6 +Serine transport 0.6598025387870273 1.0760829426851763 0.2818901634907484 1.0 0.7644964278979411 4 Q96QD8,Q9H9B4,Q96NB2 3 +Regulation of t cell mediated immunity 0.5038716356068982 1.070723901761486 0.2842935923352931 1.0 0.7644964278979411 8 P04439,Q9NUQ9,O15400 3 +Regulation of t cell proliferation 0.4050949667150842 1.0696986598589375 0.2847549697648075 1.0 0.7644964278979411 19 P02786,P30825,Q9Y6D9,Q9HCL2,P04083,P04439 6 +Late endosome to lysosome transport 0.5033771104932587 1.067953966552586 0.2855412772237113 1.0 0.7644964278979411 8 O95295,Q9HD42,Q9Y3E7,Q8WUX9 4 +Ganglioside metabolic process 0.8020094315430819 1.0674332453511235 0.2857762427031654 1.0 0.7644964278979411 3 P17900 1 +Ganglioside catabolic process 0.8020094315430819 1.0674332453511235 0.2857762427031654 1.0 0.7644964278979411 3 P17900 1 +Regulation of amyloid precursor protein catabolic process 0.4294991130883656 1.0623346752938767 0.2880837780083809 1.0 0.7661978579254907 14 O95197,P62942 2 +Regulation of erad pathway 0.5297955623493054 1.061996757260807 0.2882371573184139 1.0 0.7661978579254907 7 Q4ZIN3,P46379 2 +Regulation of amino acid transport 0.612302483069966 1.0617783736167046 0.2883363098510596 1.0 0.7661978579254907 5 O75915,Q7L0J3,P05556,P55011 4 +Prostate gland growth 0.8004820094071475 1.061524319351532 0.2884516868183056 1.0 0.7661978579254907 3 P07602 1 +Cellular response to osmotic stress 0.4759005558046946 1.0614758765787156 0.2884736902973164 1.0 0.7661978579254907 11 P30536,O95202 2 +Regulation of receptor signaling pathway via stat 0.5295388117617209 1.0606414170112304 0.2888528927414193 1.0 0.7661978579254907 7 Q9H490,P30153,Q9NX40 3 +Water homeostasis 0.4934186006124051 1.0604243978892745 0.288951567491913 1.0 0.7661978579254907 10 Q96PU5,P04062,O76024 3 +Long chain fatty acyl coa biosynthetic process 0.5293392963364014 1.05958824915534 0.2893319618338841 1.0 0.7661978579254907 7 Q53GQ0,Q9UKU0 2 +Negative regulation of cytokine production involved in inflammatory response 0.7998123275211524 1.0589346255899312 0.289629553664251 1.0 0.7665417125384233 3 P33897 1 +Motor behavior 0.7961657738934137 1.0581077470849327 0.2900063228925651 1.0 0.7666284508297431 2 P04062 1 +Positive regulation of leukocyte migration 0.4075613078369594 1.0553847123866935 0.2912494118076802 1.0 0.7680623021087062 18 Q08722,Q07021,O00429,P05067,Q99538 5 +Inorganic ion import across plasma membrane 0.4934066247441197 1.053305904840339 0.2922008135029235 1.0 0.7686061607591329 9 P23634,Q15043,P05023,P55011 4 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.7982620487636631 1.0529420341345743 0.2923675595870458 1.0 0.7686061607591329 3 Q9HD47 1 +Actin mediated cell contraction 0.4168718126309219 1.0513423135754725 0.293101399809381 1.0 0.7686061607591329 16 P16615,Q96PU5,Q9HD47,Q9UM22,P09493 5 +Mitochondrion localization 0.4069753467261942 1.0509078235409064 0.2933009268366806 1.0 0.7686061607591329 18 P07196,O60313,O75153,Q8IWA4,Q9UBK9 5 +Isoprenoid metabolic process 0.3633855076091781 1.0507522353442935 0.2933723983906313 1.0 0.7686061607591329 25 Q9H3H5,P51648,P61916,P98164,Q07954,P04035,Q9HB40,Q9BY49,Q9Y394,Q8NBN7,Q6UX07,P37268 12 +Programmed necrotic cell death 0.4277518805696615 1.0502372312253931 0.2936090558921562 1.0 0.7686061607591329 14 O00429,Q13510,P12235 3 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.4167164060832827 1.0502126158044365 0.2936203705107112 1.0 0.7686061607591329 16 P07237,Q9NR28,Q969S3,Q15118,Q07820 5 +Pigment cell differentiation 0.5001417390347668 1.049837354570084 0.293792897696284 1.0 0.7686061607591329 8 Q13637,Q9BXS5,P22413,Q86YV9 4 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.6531214882509239 1.0473744407138892 0.2949269152125287 1.0 0.7697583410129977 4 Q9BRG1 1 +Interleukin 1 production 0.473509799924812 1.0469771069211324 0.295110136897426 1.0 0.7698017895879635 11 P05067,Q99584,Q96RD7 3 +Nuclear pore complex assembly 0.4920697023786189 1.0456511878362966 0.2957221068313223 1.0 0.7698017895879635 9 Q9BTX1,Q8N1F7,Q9NQC3 3 +Folate transmembrane transport 0.7961193855700237 1.0446652694829044 0.2961777018668305 1.0 0.7698017895879635 3 Q9H2D1 1 +Folic acid transport 0.7961193855700237 1.0446652694829044 0.2961777018668305 1.0 0.7698017895879635 3 Q9H2D1 1 +Nuclear membrane organization 0.3774814142216314 1.0436269018429445 0.2966580414455335 1.0 0.7698017895879635 23 Q9HD42,P50402,Q6NUK4,Q9BTV4,Q8WUX9,Q86XL3,Q9ULX6,Q9UQN3,Q9Y3E7,Q14203,Q5JTV8,Q9H6H4,P53350 13 +Embryonic heart tube morphogenesis 0.7925007048209655 1.043126022126576 0.2968899301217802 1.0 0.7699704536320775 2 Q15363 1 +Positive regulation of extrinsic apoptotic signaling pathway 0.4913303993581872 1.041419032579336 0.2976811130844199 1.0 0.7703458097028546 9 Q9NQX7,P30154 2 +Response to endoplasmic reticulum stress 0.372918940639514 1.0413288082873906 0.2977229708580349 1.0 0.7703458097028546 86 Q8TCT9,Q15363,Q96CS3,O76024,Q9UM00,P51572,Q4ZIN3,O95881,P60604,Q9Y4P3,P07237,Q9H3N1,Q96A33,Q9BUN8,P46379,P57088,Q86TM6,Q6ZXV5,O94905,O75955,Q5VYK3,P16615,Q92905,O60313,O94874,Q7Z2K6,Q9GZP9,Q96HY6,Q13438,P27824,Q9BS26,Q9UBV2,Q6NTF9,Q13217,Q9UBU6 35 +Negative regulation of sodium ion transport 0.7951972917051425 1.0411054492199348 0.2978266107939569 1.0 0.7703458097028546 3 P46934 1 +Sensory perception of mechanical stimulus 0.4010886629809574 1.038314456053341 0.2991236806803827 1.0 0.7718071588210582 19 P98164,Q9Y5J9,Q14108,Q9Y5L4,O76024,P23634 6 +Walking behavior 0.7938971156394685 1.0360881875740948 0.3001610025103498 1.0 0.7741799660825768 3 O75844 1 +Carbohydrate derivative biosynthetic process 0.2630054344902577 1.0342357533422788 0.3010259634584364 1.0 0.7748689985712262 182 Q96AA3,Q7LG56,P50897,Q9UMR5,P00846,P46977,Q16880,Q9H490,Q9HC07,Q9H9S5,P56385,Q8NBX0,Q8TB61,O75964,P00403,Q16739,Q15118,O43292,P06865,Q6ZXV5,Q9NQX7,O15118,Q8N4A0,Q86YN1,Q9UKU0,P06576,O75746,Q8NCH0,Q15643,O60476,Q9BT22,O43505,Q8WVC6,Q92542,Q99805,Q53GQ0,Q10472,Q5H8A4,Q9NRA0,Q7LGA3,Q9Y287,P24539 42 +Regulation of tetrapyrrole metabolic process 0.7924004161670664 1.0303157745953686 0.3028617963951707 1.0 0.7780945448793117 3 O75027 1 +Regulation of action potential 0.4891628823959487 1.0290146653352292 0.303472783513272 1.0 0.7781444433398791 9 P04062,Q9HD47,Q06787 3 +Regulation of mitochondrial fission 0.452109623407823 1.027074962798424 0.304385167094557 1.0 0.7789125493026654 12 O00429,Q9NUQ9,Q9Y3D6 3 +Regulation of neutrophil migration 0.4887875665046851 1.0268673721182686 0.304482919911381 1.0 0.7789125493026654 9 Q07021,Q8NE86,O00429 3 +Copper ion transport 0.7913141567963858 1.026128529229502 0.304831004292819 1.0 0.778966173658176 3 Q02790,Q8N4V1 2 +Macroautophagy 0.3588050250681007 1.025817461599915 0.3049776337493999 1.0 0.778966173658176 121 P36543,Q93050,P09601,P13473,Q8WVM8,Q9BRG1,O95721,P46934,Q9HD42,Q9H0U4,Q9UPT5,P04062,P62820,Q96A65,O15118,Q96KQ7,Q86Y82,P05141,Q9Y371,O95295,P27544,P53365,Q99623,P16615,O14681,P21796,Q9Y487,P42345,Q16543,P12235,Q9Y6I9,Q96HY6,Q8TBX8,Q9Y3E7,O14964,O15269,Q9NQ88 37 +Positive regulation of t cell mediated immunity 0.5224941817366368 1.0234785263903448 0.3060816478169217 1.0 0.7808762597718751 7 P04439,Q9NUQ9,O15400 3 +Terpenoid metabolic process 0.4032074631424717 1.022132879228456 0.3067180134134903 1.0 0.7816892067275176 18 P51648,P98164,Q9BY49,Q9HB40,Q8NBN7,Q6UX07,P37268 7 +Astrocyte development 0.5644044048394987 1.0220508031170377 0.3067568560990912 1.0 0.7816892067275176 6 P05067,P08670 2 +Golgi to vacuole transport 0.4950478074316593 1.0213360391286257 0.3070952573509165 1.0 0.7820674380120306 8 Q8N1B4 1 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.7868621370171979 1.020131708776197 0.3076660002229143 1.0 0.7820674380120306 2 Q07954 1 +Negative regulation of receptor signaling pathway via jak stat 0.786862137017192 1.0201317087761728 0.3076660002229259 1.0 0.7820674380120306 2 P30153 1 +Negative regulation of receptor signaling pathway via stat 0.786862137017192 1.0201317087761728 0.3076660002229259 1.0 0.7820674380120306 2 P30153 1 +Cardiac muscle contraction 0.3987369757062196 1.0199038328588654 0.3077740715861523 1.0 0.7820674380120306 19 P16615,P10253,Q96PU5,Q9HD47,P42345 5 +Response to oxidative stress 0.3676258375264193 1.019729935379603 0.3078565602878436 1.0 0.7820674380120306 106 O43169,P33897,Q969S3,P09601,Q7LG56,P05067,P30519,P00374,Q15392,P07237,P04062,Q15118,Q9UJ14,Q16134,Q15165,P16615,Q9NP80,Q07820,Q7Z2K6,Q6NUK1,Q9NR28,Q8N0U8,Q99720,P33527 24 +Regulation of mammary gland epithelial cell proliferation 0.6459523954036395 1.0166294758903665 0.3093297265855677 1.0 0.7834008372119183 4 Q99623,Q9NQC3 2 +Positive regulation of muscle tissue development 0.6458648492584302 1.0162544636941009 0.309508226845494 1.0 0.7834008372119183 4 O75955 1 +Positive regulation of skeletal muscle tissue development 0.6458648492584302 1.0162544636941009 0.309508226845494 1.0 0.7834008372119183 4 O75955 1 +Regulation of neutrophil chemotaxis 0.4941148227879031 1.0161193252603826 0.3095725674188498 1.0 0.7834008372119183 8 Q07021,Q8NE86,O00429 3 +Regulation of anion transport 0.4682462159129547 1.0150815720566837 0.3100669451125453 1.0 0.7837472321311338 11 Q7L0J3,Q13546,O75915,P05556,P08183,P55011 6 +Positive regulation of triglyceride metabolic process 0.7883452032036643 1.014693691613734 0.3102518621633183 1.0 0.7839133682090452 3 Q8WTV0 1 +Cell motility involved in cerebral cortex radial glia guided migration 0.7851705666760659 1.0132469681722676 0.3109422111984892 1.0 0.7847532321766963 2 Q8WXH0 1 +Chromosome attachment to the nuclear envelope 0.7851705666760654 1.0132469681722651 0.3109422111984903 1.0 0.7847532321766963 2 P02545 1 +Regulation of cardiac conduction 0.5622013098637604 1.0113689358440443 0.3118398832743305 1.0 0.7849448593537708 6 P20020,P23634,P16615 3 +Regulation of heart rate by chemical signal 0.7840428531153141 1.0086607518767965 0.3131373607142609 1.0 0.7869715022612556 2 P09493 1 +Calcium ion export across plasma membrane 0.7840428531153134 1.008660751876793 0.3131373607142627 1.0 0.7869715022612556 2 P20020 1 +Neuron development 0.2566811384003628 1.0078212549737782 0.3135402800871989 1.0 0.7870201832419133 202 Q96G23,O00264,Q9NZJ7,O14949,Q32P28,Q9Y6M7,P50897,Q16880,Q02790,Q9NQC3,P05067,Q92859,P00374,P07196,P46934,P04062,P54802,Q16739,Q9NR77,Q06787,Q9NQX7,O75503,Q8N5V2,O75312,O15031,Q96PU5,P42892,P08670,P30536,Q9NV96,Q14108,P35613 32 +Positive regulation of cell adhesion molecule production 0.7857454130478854 1.0046927345941936 0.3150448276846402 1.0 0.7874907407567657 3 Q5KU26 1 +Long term synaptic potentiation 0.4837577939913645 1.004495213618659 0.3151399771433492 1.0 0.7874907407567657 10 Q92542,P05067,Q99538 3 +Energy derivation by oxidation of organic compounds 0.3457883071840702 1.0036488238738548 0.3155479123207909 1.0 0.787784142718569 133 Q9UDW1,P33897,O14949,Q15070,Q9Y255,P00846,O43676,O95139,Q9NZ45,P56385,O14548,O75964,P04062,P00403,P21912,Q16134,Q9H3K2,O75746,O75208,P10253,P03886,Q13423,P13073,P14406,O96000,Q9BSK2,Q7KZN9,P46020,P24539 29 +Locomotor rhythm 0.6428934920647951 1.0035330635817947 0.3156037323561464 1.0 0.787784142718569 4 P54802 1 +Pigment metabolic process 0.3488599438460228 1.0015433618128065 0.3165641874765681 1.0 0.7889513683339857 32 P22830,P09601,Q7KZN9,P30519,P33527 5 +Positive regulation of cold induced thermogenesis 0.4098970243379227 1.0006791181323498 0.316981966047114 1.0 0.7894853435904057 16 P23786,Q16836,Q96E52 3 +Response to iron ion 0.559698009201032 0.9992389667507108 0.3176789435389011 1.0 0.790830587303313 6 P02786,P09601 2 +Neuroblast proliferation 0.4654227969149455 0.9979900257279508 0.3182841952848989 1.0 0.7917330068814652 11 Q8NCG7,O15031 2 +Membrane protein intracellular domain proteolysis 0.783981951494632 0.9979156359789552 0.3183202692663869 1.0 0.7917330068814652 3 Q92542,Q8TCT8 2 +Regulation of membrane tubulation 0.7812235692134255 0.9972081712987776 0.3186634754818311 1.0 0.7917330068814652 2 Q9Y371 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class ii 0.7812235692134235 0.9972081712987704 0.3186634754818347 1.0 0.7917330068814652 2 Q99538 1 +Natural killer cell activation 0.4834337484910809 0.9962578876393192 0.3191248595473261 1.0 0.7917330068814652 9 Q96L92,P11279 2 +Embryo implantation 0.483332587014922 0.9956799334489216 0.3194056830091099 1.0 0.7921309114445383 9 Q07021,Q02790,P35613 3 +Protein localization to ciliary membrane 0.5969549340406249 0.9921055598188188 0.3211460346711021 1.0 0.7940273138613283 5 Q15643,Q9UPT5 2 +Positive regulation of calcium ion transport 0.3951543446522997 0.9918782755931216 0.3212569077368092 1.0 0.7940273138613283 19 P20020,Q13586,P30536,O76024 4 +Pyramidal neuron differentiation 0.5959180824253775 0.9874099549868576 0.3234417060682935 1.0 0.797334538647593 5 O14949 1 +Hepatocyte differentiation 0.7784042853115315 0.9857746660579514 0.3242437001540275 1.0 0.7978117530539904 2 Q16822 1 +Positive regulation of unsaturated fatty acid biosynthetic process 0.7784042853115102 0.9857746660578656 0.3242437001540696 1.0 0.7978117530539904 2 P33897 1 +Response to axon injury 0.4077284124795107 0.9849465297246136 0.3246503362560231 1.0 0.7981235935227375 16 P07196,P00374,Q96G23 3 +Heart morphogenesis 0.3502711547882506 0.9837561955697126 0.3252354019814483 1.0 0.7981235935227375 30 O75844,P10253,Q15363,Q9NQC3,O96028,P42345,P62942 7 +Nuclear membrane reassembly 0.4451957685528093 0.9831478818762052 0.3255346612698213 1.0 0.7981235935227375 12 Q9HD42,Q8WUX9,Q86XL3,Q6NUK4,Q9UQN3,Q9Y3E7,Q9H6H4 7 +Positive regulation of mononuclear cell migration 0.4798085060570534 0.9816712457663586 0.3262618356050817 1.0 0.7981235935227375 10 Q08722,P05067,Q07021 3 +Negative regulation of autophagy of mitochondrion 0.6376738715455574 0.981219475607845 0.326484522048946 1.0 0.7981235935227375 4 P30536 1 +Amyloid fibril formation 0.4796442001783105 0.980722283132995 0.3267297121759913 1.0 0.7981235935227375 10 P62942 1 +Plasma membrane repair 0.4877339112618488 0.98047570739904 0.3268513551894316 1.0 0.7981235935227375 8 Q9HD42,Q9Y3E7,Q8WUX9 3 +Cellular response to molecule of bacterial origin 0.3499217730825775 0.9803433641835284 0.326916656093696 1.0 0.7981235935227375 30 P08670,Q86UE4,Q8WTV0,Q9NUQ9 4 +Positive regulation of fatty acid biosynthetic process 0.7786238014664412 0.9773584254534554 0.3283917377011813 1.0 0.7984851879599516 3 Q92604,P33897 2 +Regulation of response to oxidative stress 0.369713678555272 0.9759910698068928 0.3290688897441167 1.0 0.7992193825136839 23 P07237,P33897,Q9UJ14,Q9NP80,Q07820,P00374 6 +Cardiac conduction 0.3967931905860964 0.97321370052557 0.3304471029813829 1.0 0.8019743897817548 18 O75844,P16615,Q6PI78,P20020,Q9HD47,P23634,P05023,P62258 8 +Phagocytosis recognition 0.5921752352116978 0.9704738625774816 0.3318103470961269 1.0 0.8030179257991941 5 Q5KU26,Q8WTV0 2 +Regulation of membrane permeability 0.3876524538212302 0.9694068779804894 0.3323422219895706 1.0 0.8030179257991941 20 P45880,P52789,P42345,P05141,P12235 5 +Regulation of response to endoplasmic reticulum stress 0.3754142673556322 0.9680914828703042 0.3329986831425886 1.0 0.8032542407323658 22 Q96HY6,Q92905,P46379,O60313,P57088,Q86TM6,O76024,P51572,Q4ZIN3,O95881 10 +Angiogenesis involved in wound healing 0.7755217146080099 0.9654817800031807 0.3343035575600264 1.0 0.8056850487622915 3 P15291,P42785 2 +Vasculogenesis 0.4768729519094711 0.9647246429090458 0.3346827488801964 1.0 0.8057131915757877 10 P06756,O95470 2 +Transepithelial chloride transport 0.7752397067118002 0.964403027076872 0.3348439051826375 1.0 0.8058062072397391 3 Q86WC4,P55011 2 +Lysine metabolic process 0.6334292000692251 0.9631079238655104 0.3354933656740209 1.0 0.8060862217701763 4 Q9BQT8 1 +Negative regulation of defense response to virus 0.4845479092142561 0.9627049130823356 0.3356956304437453 1.0 0.8060862217701763 8 Q07021,O43657 2 +Vesicle tethering 0.5903478596480015 0.9622136442286844 0.3359422967056149 1.0 0.8060969058422955 5 Q14849,O95772 2 +Regulation of cation channel activity 0.3867115787332907 0.9618625140627926 0.3361186707534842 1.0 0.8060969058422955 20 P05067,Q13586,P27105,P62942 4 +Pyrimidine containing compound transmembrane transport 0.774258292604455 0.9606501133235328 0.3367281223601335 1.0 0.8060969058422955 3 Q9BSK2 1 +Regulation of hormone metabolic process 0.5898755779022793 0.9600797583358378 0.337015075002717 1.0 0.8063107123655401 5 O75844,P16435 2 +Estrogen biosynthetic process 0.7719199323371928 0.9595538948762063 0.3372797826694631 1.0 0.8066505929516578 2 Q53GQ0 1 +Regulation of mitochondrial membrane permeability 0.4094902649400311 0.9584663978827755 0.3378276276755128 1.0 0.8076671418472728 15 P52789,P45880,P05141,P12235 4 +Positive regulation of phagocytosis 0.4757343526203985 0.9581563959022692 0.3379839010644341 1.0 0.8077471356470869 10 Q08722,Q06481,Q12907,Q08431 4 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.5889632134998055 0.9559586044586316 0.3390931487979198 1.0 0.8083420223428485 5 P09493,P42892 2 +Cellular response to oxygen levels 0.335662276091903 0.9534283640250756 0.3403730759073529 1.0 0.8094664188423376 41 Q8N511,P07237,Q9Y4P3,Q96A26,Q99623,P09601,P49327,P02545,Q15118,Q15904,Q9Y487,Q9NQ88,P42345 13 +Cardiac chamber development 0.3733726616835188 0.9508398786816586 0.3416856653026912 1.0 0.8098258092597477 22 O75844,Q15643,Q6PI78,P09493,O96028,P62942 6 +Sequestering of triglyceride 0.6301833568406185 0.9492807412602066 0.3424778458689679 1.0 0.8105595083052208 4 Q9BZF1,P22413,O60664 3 +Protein transport within lipid bilayer 0.7691006484352853 0.948188468202252 0.343033516731666 1.0 0.8105595083052208 2 Q9BRK0 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.7707404122968864 0.947214066405632 0.3435297090241613 1.0 0.810690669627524 3 O75844 1 +Negative regulation of cellular response to insulin stimulus 0.4735674471072796 0.9456640437172704 0.3443199674726185 1.0 0.8109039443822665 10 Q06481,Q8TBX8 2 +Negative regulation of steroid metabolic process 0.7682548632647328 0.9447831415327874 0.3447696003473344 1.0 0.8111090684458642 2 P05023 1 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.5863253645247386 0.94405209575469 0.3451430272989613 1.0 0.8115858743458235 5 Q9Y6D9,P12270 2 +Regulation of oxidative phosphorylation 0.4731156980463356 0.9430610410474628 0.3456496815806558 1.0 0.8116964913934955 10 P14406,P33897,Q9BSK2 3 +Positive regulation of cholesterol storage 0.767691006484333 0.9425140457704712 0.3459295234350765 1.0 0.8116964913934955 2 Q8WTV0 1 +Regulation of multicellular organism growth 0.4018040121769822 0.9420297972650143 0.3461773845763654 1.0 0.8116964913934955 16 O75844,Q9HCL2,O95470 3 +Regulation of cysteine type endopeptidase activity 0.3455374114365173 0.9401418751206292 0.3471447917382599 1.0 0.8128057298905431 51 P51812,Q9NR28,P16435,O14737,Q96A26,Q9NZJ7,Q9P0J0,Q15418,Q15392 9 +Positive regulation of atp metabolic process 0.5064842004480943 0.9392695977963612 0.3475923436853434 1.0 0.8133152310085324 7 O75746,P00403 2 +Glycosylceramide catabolic process 0.7682948281799175 0.9378889671745264 0.3483014736021577 1.0 0.8146439515936669 3 P04062 1 +Skeletal muscle cell differentiation 0.4800391679266951 0.9375913909113004 0.3484544373367253 1.0 0.8147119923084403 8 Q92841,Q9BYT8,P50402 3 +Photoreceptor cell development 0.5847195384355175 0.93681039681088 0.3488560963417586 1.0 0.8153612457852688 5 P54802 1 +Membrane raft assembly 0.584327311237122 0.9350423714791694 0.3497664636048578 1.0 0.8160390319720292 5 Q14254,Q9UNF0,O75955 3 +Membrane depolarization 0.4244233649862288 0.9336104338101632 0.3505048812227875 1.0 0.8168464235101002 13 Q96PU5,P33897,Q9HD47 3 +Response to cell cycle checkpoint signaling 0.7670550780628778 0.9331667535509406 0.3507338774844988 1.0 0.816847277696724 3 O75844 1 +Protein containing complex remodeling 0.7651536509726327 0.932314401365024 0.3511740672662897 1.0 0.8169028624787532 2 Q8WTV0 1 +Positive regulation of transport 0.2523405215622986 0.9321585983235996 0.3512545682058559 1.0 0.8169028624787532 198 Q15154,O43707,Q12907,Q9H4A6,P50570,Q03164,Q05D32,Q9Y255,P50897,P04083,O76024,P51572,P55011,Q08431,P46934,Q5T9L3,Q07954,P20020,P12270,P05026,Q9P2W9,P27105,Q06787,Q9C0E2,Q9H4M9,O75955,Q9Y371,O95295,Q16822,P61978,O75312,P50402,Q96PU5,P49755,Q9NR31,Q14012,P11279,Q9UII2,Q08722,O14737,Q16625,Q12846,Q9Y3D6,Q9Y282,O95563,Q13586,Q92544,P30536,O00429,O00560,Q99758,Q9NV96,Q9NRA0,P08183,O14964,Q06481,P62258 57 +Phospholipid biosynthetic process 0.3540155279361053 0.9311090771978908 0.3517971436296738 1.0 0.8170980057664378 62 Q9HBU6,Q9H490,Q9NPH0,Q92643,Q8NF37,O43292,Q86YN1,Q9NX62,Q9NTJ5,Q92604,Q9HCL2,Q9BTU6,Q9UG56,O95674,Q96N66,Q10713,O14735,Q8TBX8,Q5H8A4,Q9NRA0,Q9NUQ2,O15269 22 +Negative regulation of dendritic spine morphogenesis 0.7645897941922646 0.9300503589508698 0.3523450111956197 1.0 0.8171754189877081 2 Q8N5V2 1 +Positive regulation of ubiquitin protein ligase activity 0.583115627109346 0.9295824907143062 0.3525872965216068 1.0 0.8174010043082862 5 Q16763,P63208,P53350 3 +Glycosyl compound catabolic process 0.4366994299058201 0.9293119364077392 0.3527274510274618 1.0 0.8174377890794985 12 P08236,P04062,Q13126,Q9NUJ1,Q9BTY2,P06280 6 +Nervous system process 0.3577669074680955 0.9289867263054096 0.3528959653672781 1.0 0.817540248052338 112 O00264,P50897,O76024,P05067,P23634,P07196,P17900,P04062,Q9BRK0,Q9Y5J9,Q9Y5L4,Q06787,O14773,O75746,P10253,O60313,P04035,O75844,Q92542,Q6P4Q7,Q14108,Q9H6K4 22 +Positive regulation of dna dependent dna replication 0.5450850207177333 0.9286246108236296 0.35308366290644 1.0 0.8176870601886111 6 Q9UJZ1 1 +Response to amino acid starvation 0.4050580356348324 0.9271915323334968 0.3538270985031966 1.0 0.8187536401847249 15 Q9Y371,Q96QD8,P42345,P49327 4 +Neurotransmitter secretion 0.3766365027444775 0.9269444139430216 0.353955395603319 1.0 0.8187536401847249 21 Q7L0J3,Q12846,P16615,P50897,Q06787,O95721 6 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.7637440090216889 0.9266560581663592 0.3541051391828453 1.0 0.8187536401847249 2 Q8N5M9 1 +Regulation of biological process involved in symbiotic interaction 0.4532782918550502 0.9246606132769012 0.3551424731971115 1.0 0.8195691390236501 11 Q9BTY2,P07237,Q9UPT5 3 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4527668430258614 0.921580528395126 0.3567474189390838 1.0 0.8221619226660477 11 Q07820,P30154 2 +Quaternary ammonium group transport 0.7638721463279352 0.9210588086234988 0.357019724354624 1.0 0.8224583982768344 3 Q9HC21 1 +Response to activity 0.3985565592951522 0.9185517717704456 0.3583300677545746 1.0 0.8242039437419093 16 Q15388,Q9UDX5 2 +Inner ear receptor cell development 0.502504408648742 0.9184104419921236 0.3584040260151833 1.0 0.8242039437419093 7 P54802,Q9Y6M7 2 +Positive regulation of monooxygenase activity 0.580387880039599 0.917302441985082 0.3589841781026339 1.0 0.8248631205871075 5 P00374,Q8WTV0 2 +Detection of stimulus 0.3926328811824221 0.9169432424222644 0.3591723826919151 1.0 0.8248631205871075 17 Q13586,Q8WTV0,P30536,P04439 4 +Positive regulation of glial cell proliferation 0.7606427967296236 0.9142287128559076 0.360596679783266 1.0 0.8248631205871075 2 P30536 1 +Negative regulation of ire1 mediated unfolded protein response 0.7606427967296114 0.9142287128558588 0.3605966797832916 1.0 0.8248631205871075 2 Q96HY6 1 +Myeloid cell activation involved in immune response 0.4031389026830509 0.9136701094414512 0.3608902147144548 1.0 0.8248631205871075 15 P09601,Q9NRA0,Q99584 3 +Calcium ion regulated exocytosis 0.4679452759173736 0.9133051729765423 0.3610820624629376 1.0 0.8248631205871075 10 Q9BRK5 1 +Cellular response to amyloid beta 0.4756102900340132 0.9129685377328328 0.3612590889152609 1.0 0.8248631205871075 8 P05067,P33527,Q99538 3 +Response to amyloid beta 0.4756102900340132 0.9129685377328328 0.3612590889152609 1.0 0.8248631205871075 8 P05067,P33527,Q99538 3 +Negative regulation of response to endoplasmic reticulum stress 0.421144116483229 0.9120097616755656 0.3617635788796827 1.0 0.8255791319540849 13 O76024,Q96HY6,O60313 3 +Regulation of amyloid beta clearance 0.5405808117560236 0.9069403527408904 0.3644383404727702 1.0 0.8293809568475466 6 Q16850,Q07954,P04035 3 +Fatty acid alpha oxidation 0.6198819353709581 0.9055411302438632 0.3651787803913082 1.0 0.829849579868798 4 A1L0T0 1 +Myeloid leukocyte mediated immunity 0.3796523428144597 0.9053591859548922 0.3652751305641128 1.0 0.829849579868798 20 Q8N5M9,P09601,Q9NRA0,Q99584 4 +Cytosolic transport 0.3579692092755993 0.9046911152135424 0.3656290493436769 1.0 0.8300801717408917 73 Q8N1B4,O75436,Q9UNK0,O15260,O60499,Q86VS8,Q8N2H4,P33176,O75503,Q8IUD2,Q4J6C6,Q9UID3,P61106,P42566,O60271,O95249,Q9Y5X3,O60749,Q8NBN3,Q96RL7,O15498,P51151,P14373,P11279,Q14203,P49257,Q13190,O43752,P61160,Q9UNH7,Q92538,P40616,Q9Y3E7,P35241,Q96ED9 35 +Regulation of lipoprotein particle clearance 0.4997254189009146 0.9038666950576476 0.3660660911123181 1.0 0.8301879721576821 7 P61978,Q9Y2B0 2 +Centriole centriole cohesion 0.5773137697516798 0.9034826869814194 0.3662697727666211 1.0 0.8301879721576821 5 P35222,Q14203,Q9BV73,Q9C0F1 4 +Extrinsic apoptotic signaling pathway 0.3343890261611209 0.9004225577937174 0.3678954206623011 1.0 0.8323523156848828 44 Q9NR28,P06756,P30153,Q12846,P09601,P02545,Q9P0J0,P30154,P61289,Q9NQX7,Q07820 11 +Collagen metabolic process 0.4656109553407832 0.8998949228505202 0.3681761722967676 1.0 0.8325787077081849 10 Q92791,P08670 2 +Intraciliary transport involved in cilium assembly 0.756977727657181 0.8995803056597546 0.3683436418213124 1.0 0.8325787077081849 2 Q15154 1 +Negative regulation of developmental growth 0.4650673455353177 0.8967742823433379 0.3698393737169527 1.0 0.8329844466457639 10 Q99538,Q8N0X7,Q9NQC3 3 +Antiviral innate immune response 0.5757698195579217 0.8965500315629525 0.3699590717423304 1.0 0.8329844466457639 5 Q9NVI7 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4983238787511082 0.8965390586095745 0.3699649293779712 1.0 0.8329844466457639 7 O76024,O60313 2 +Fatty acid homeostasis 0.5379188000066772 0.8941463324783497 0.3712436022040393 1.0 0.8341883060116045 6 P33897 1 +Positive regulation of anion transport 0.537245263980761 0.8909119047817665 0.372976433134913 1.0 0.8354848003911646 6 P05556,P08183,P55011 3 +Cotranslational protein targeting to membrane 0.3999022349147396 0.8908975513148775 0.3729841340913844 1.0 0.8354848003911646 15 Q9UHB9,P43307,P49458,Q15629,Q9H173 5 +Receptor metabolic process 0.3273102183035404 0.890251435127044 0.373330891881388 1.0 0.8354848003911646 39 P02786,Q9Y371,Q8IZ07,P46934,P50570,O00560,Q07954,Q6IAA8,Q06787,O75955,P42892,Q99538 12 +Negative regulation of glucose transmembrane transport 0.5738992961961613 0.8881586712988777 0.3744554063893317 1.0 0.835715706384241 5 Q06481 1 +Regulation of transporter activity 0.3406495963588549 0.8864040642313291 0.3753998299238474 1.0 0.835715706384241 51 P46934,O43707,Q99623,Q04656,Q13586,P50570,Q03164,Q96PU5,P62258,Q9HD47,P27105,Q06787,Q9NRA0,P05067,P08183,P62942 16 +Positive regulation of fatty acid beta oxidation 0.7545149284279944 0.8856037688861832 0.3758310799428928 1.0 0.835715706384241 3 P33897 1 +Positive regulation of fatty acid oxidation 0.7545149284279944 0.8856037688861832 0.3758310799428928 1.0 0.835715706384241 3 P33897 1 +Receptor internalization 0.3453796167731577 0.884603211608933 0.376370673910616 1.0 0.835715706384241 25 P02786,Q8IZ07,P46934,O00560,Q07954,Q06787,O75955 7 +Multi multicellular organism process 0.3435809225011354 0.8842006437879383 0.3765879108931493 1.0 0.8359158589079457 27 P15291,Q9BQE5,Q7Z739,Q02790,Q15363,Q9NRA0,Q07021,Q96QD8,P35613,Q9UIQ6 10 +Regulation of glial cell proliferation 0.6147407195726995 0.8838030546491883 0.3768025371485739 1.0 0.8361100832746865 4 Q96G23 1 +Negative regulation of microtubule polymerization 0.5351612182285914 0.880911133158036 0.3783659211548034 1.0 0.8365379862892929 6 Q02790,Q14155,Q15691 3 +Negative regulation of neuron projection development 0.3520341354699343 0.8807288117274451 0.3784646184919309 1.0 0.8365379862892929 24 Q96G23,Q15375,Q9NR77,Q02790,Q9NQC3,Q9NQX7,P08670,Q8N5V2,Q8N0X7 9 +Peptidyl glutamic acid modification 0.5721389722748403 0.880269613792105 0.3787132695554513 1.0 0.8365379862892929 5 Q8N0U8 1 +Cellular response to lipoprotein particle stimulus 0.6128535393829188 0.8758404793957493 0.3811167606348538 1.0 0.8387290329616466 4 O15118 1 +Regulation of leukocyte migration 0.3377567435303489 0.8754290476045842 0.3813405004362977 1.0 0.8387290329616466 31 Q08722,P46108,P09601,Q07021,O00429,P05067,Q99538 7 +Enamel mineralization 0.7513047972808304 0.873491715153495 0.3823951200359978 1.0 0.8387290329616466 3 Q13586 1 +Amelogenesis 0.7513047972808304 0.873491715153495 0.3823951200359978 1.0 0.8387290329616466 3 Q13586 1 +Vesicle targeting rough er to cis golgi 0.4446551292893936 0.8728389065304448 0.3827508898123448 1.0 0.8387290329616466 11 Q15363,P49755 2 +Response to atp 0.7496475895122614 0.8704154254227767 0.3840734198683129 1.0 0.8396137079924384 2 Q96RD7 1 +Cellular response to unfolded protein 0.3339172805059788 0.8685363119706361 0.3851008026357629 1.0 0.8396137079924384 33 Q9Y4P3,P48723,Q9GZP9,Q96HY6,Q13438,Q92905,Q9BUN8,P57088,Q15363,O76024,Q6NTF9,Q7Z2K6 12 +Positive regulation of immune effector process 0.3252115142393764 0.8675522869408336 0.3856394760722237 1.0 0.8396137079924384 39 Q12846,Q99623,P09601,P01889,P04439,P11279,Q9NUQ9,Q9NRA0,O15400,Q06481,O96028 11 +Cellular response to starvation 0.3279510922339971 0.8646592734225267 0.3872258290353885 1.0 0.8396137079924384 36 Q9Y371,Q9Y4P3,P54619,P21964,P13473,P04062,P49327,Q9P2J5,Q96QD8,Q96KQ7,P42345 11 +Alcohol metabolic process 0.3583313368590263 0.8643528875487351 0.387394065177078 1.0 0.8396137079924384 88 Q9BQE5,Q9NZC3,Q14849,Q8NBN7,P05067,P00374,Q15392,Q9H2C2,P51648,P04062,Q13510,Q14534,Q8WTV0,Q6UX07,O15118,Q9BW91,Q9NX62,O75845,P04035,Q15125,Q15800,Q16850,P16435,Q10713,Q9BY49,Q14739,Q9NRA0,O15269 28 +Positive regulation of small molecule metabolic process 0.3909461189068176 0.8636940865074748 0.3877559630049523 1.0 0.8396137079924384 16 P16435,P33897,O75746,Q92604,P00403,P05067 6 +Synaptic vesicle membrane organization 0.5314092453631606 0.8629349777257734 0.3881732180860626 1.0 0.8396137079924384 6 O95721,Q12846,O43760 3 +Er overload response 0.5675843805301704 0.8598953510242274 0.3898467314339577 1.0 0.8396137079924384 5 Q96A33 1 +Phosphatidylinositol 3 kinase signaling 0.4423546916275142 0.8590577390694683 0.390308661545566 1.0 0.8396137079924384 11 P46934,Q10713 2 +Heparan sulfate proteoglycan biosynthetic process 0.4910485128031064 0.8585878936530706 0.3905679196400484 1.0 0.8396137079924384 7 Q99805,Q7LGA3 2 +Heparan sulfate proteoglycan metabolic process 0.4910485128031064 0.8585878936530706 0.3905679196400484 1.0 0.8396137079924384 7 Q99805,Q7LGA3 2 +Nuclear migration 0.4127890081829485 0.8571528859479793 0.3913603965102272 1.0 0.8396137079924384 13 Q8WXH0,Q15154,Q5SNT2,Q9UH99,Q14203 5 +Positive regulation of interferon gamma production 0.5667920704684808 0.8563568496420222 0.3918004247842062 1.0 0.8396137079924384 5 Q9NUQ9 1 +Regulation of myelination 0.4575263409395236 0.8535832563930537 0.3933359390426176 1.0 0.8396137079924384 10 P42345,O75312,O75746 3 +Protein targeting to peroxisome 0.5660790195335622 0.853173840384652 0.3935629079296598 1.0 0.8396137079924384 5 P40855 1 +Regulation of chondrocyte differentiation 0.5290210272293223 0.8515129832960073 0.3944844542449717 1.0 0.8396137079924384 6 P16435,Q8N5W9 2 +Peptidyl lysine hydroxylation 0.4643438141697327 0.850581052698107 0.3950021182899828 1.0 0.8396137079924384 8 Q92791,Q96AY3 2 +Regulation of generation of precursor metabolites and energy 0.3285386930417898 0.849686012268817 0.3954996772271348 1.0 0.8396137079924384 43 Q9H3K2,P33897,Q9NZ45,O75746,Q99623,O14548,Q9BSK2,Q9Y255,P22413,Q9NRA0,P05067,P14406,Q9NQ88 13 +Circulatory system process 0.3564029286693412 0.8494623506184548 0.395624071348384 1.0 0.8396137079924384 83 P09601,P53985,Q6PI78,O75787,Q9NZ08,P23634,O15439,P05023,P98164,Q07954,Q9HB40,P20020,Q9HD47,Q96QD8,Q9UIQ6,P16615,P10253,Q96PU5,P42892,P42345,O75844,Q16625,P30825,O00429,P08183,P33527,P09493,P42785 28 +Regulation of receptor binding 0.744802400321546 0.849044278677209 0.3958566542145314 1.0 0.8396137079924384 3 P16615 1 +Phagolysosome assembly 0.6062443942327368 0.848030949478211 0.3964207347416648 1.0 0.8396137079924384 4 Q9BZG1,P61106 2 +Negative regulation of endoplasmic reticulum unfolded protein response 0.5645704110133285 0.846444336581303 0.3973049137810336 1.0 0.8396137079924384 5 Q96HY6 1 +Lung alveolus development 0.5644683404594636 0.8459892663725183 0.3975587321477176 1.0 0.8396137079924384 5 O60476,Q16706 2 +Generation of precursor metabolites and energy 0.2471781277374574 0.8442082323826923 0.3985530550738432 1.0 0.8396137079924384 193 Q9UDW1,P54619,P33897,P52789,O14949,Q15070,Q9Y255,P00846,O43676,P05067,O95139,Q9NZ45,P56385,O14548,O75964,P04062,P00403,P21912,P22413,Q16134,P06576,P22830,Q9H3K2,O75746,Q99623,O75208,P10253,P03886,Q13423,P13073,Q9UJZ1,P14406,Q9UII2,P42345,O96000,P12235,P16435,Q9BSK2,Q15067,Q9P0J0,O15460,Q9BRR6,Q9NRA0,Q7KZN9,Q9NQ88,P46020,P24539 47 +Regulation of monooxygenase activity 0.4557374394619132 0.8433668467191917 0.3990233077057814 1.0 0.8396137079924384 10 P00374,P06280,P16435,Q8WTV0 4 +Amine catabolic process 0.604609074915232 0.8411692851820062 0.4002531048038769 1.0 0.8396137079924384 4 P21964 1 +Negative regulation of lipid storage 0.7420355229771652 0.8403284084754555 0.4007242773527988 1.0 0.8396137079924384 2 P06756 1 +Sterol homeostasis 0.392401480761691 0.8383015884976208 0.4018613439830227 1.0 0.8396137079924384 15 P33897,P61916,Q5BJF2,Q8WTV0,Q9H4M9,O15118 6 +Negative regulation of amyloid beta clearance 0.7416807670614691 0.8373509417700081 0.4023953327108207 1.0 0.8396137079924384 3 Q16850,P04035 2 +Melanocyte differentiation 0.7413987591652446 0.8362960011243192 0.4029884022486505 1.0 0.8396137079924384 3 Q86YV9,P22413 2 +Regulation of hormone levels 0.3454451734326673 0.8351216404465185 0.4036492233719553 1.0 0.8396137079924384 62 P53985,O75787,P04083,Q14849,Q8NBN7,Q8TAD4,P05023,O95470,Q8NBQ5,P62820,Q15043,Q9HB40,Q6UX07,Q16822,Q16836,Q8N183,Q8N5M9,P50416,Q9Y394,P42892,O75844,P16435,Q53GQ0,Q12846,O95563,P30536,Q969M3 27 +Rhythmic behavior 0.5620191124184328 0.8350789743841456 0.4036732440776966 1.0 0.8396137079924384 5 P54802 1 +Cellular response to extracellular stimulus 0.3338473342400948 0.8342449992472103 0.4041429383095813 1.0 0.8396137079924384 49 Q9Y371,Q8TB36,P54619,Q9Y4P3,P21964,P09601,P13473,P04062,P49327,P20020,Q9P2J5,Q96QD8,Q96KQ7,P42345 14 +Embryonic digit morphogenesis 0.4863027072346438 0.8339189282987127 0.4043266701445656 1.0 0.8396137079924384 7 Q9NX62 1 +Positive regulation of amine transport 0.6028208744710786 0.8336753689605275 0.4044639416018711 1.0 0.8396137079924384 4 Q15042,P05556,P55011 3 +Lipid storage 0.3706046156717694 0.8332777480476494 0.4046881029574041 1.0 0.8396137079924384 20 P06756,Q9C0B1,P17900,P04062,Q14534,P50416,Q8WTV0,P22413,P07686,Q9H6V9,Q9H4M9,O95674 12 +Regulation of lipid transport 0.3531308677585764 0.8323687653675418 0.4052008268035174 1.0 0.8396137079924384 23 Q9H2C2,O15260,Q9Y3D6,P30536,Q9Y255,Q99758,Q9NV96 7 +Response to arsenic containing substance 0.3914240983795239 0.8314688913446836 0.4057087950544211 1.0 0.8396137079924384 15 P09601 1 +Mammary gland development 0.3587261192652981 0.827630853218093 0.4078795896902805 1.0 0.8396137079924384 22 Q13505,Q99623,Q04656,P52789,Q9UNS2,P49327,P00403,Q9NQC3 8 +Feeding behavior 0.4601355968308462 0.8273877486816454 0.4080173223237098 1.0 0.8396137079924384 8 P05067,Q9GZP9 2 +Cellular response to topologically incorrect protein 0.3200923243310759 0.8264227133637506 0.4085643433298103 1.0 0.8396137079924384 38 P48723,Q9GZP9,Q96HY6,Q13438,Q9BUN8,P46379,Q15363,O76024,Q7Z2K6 9 +Plasma membrane to endosome transport 0.6008271976027979 0.8253320174850582 0.4091831191932911 1.0 0.8396137079924384 4 P61020,Q99523 2 +Regulation of intrinsic apoptotic signaling pathway 0.3347443110737531 0.8216758433579553 0.4112614111601851 1.0 0.8396137079924384 51 P07237,P45880,Q9Y3D6,Q8N2F6,Q7LG56,O00429,P23246,O60313,Q9P0J0,Q86TM6,O76024,Q07820,P51572,O95881,Q9H300 15 +Glial cell migration 0.4194994162335405 0.8210617813006663 0.4116110781601279 1.0 0.8396137079924384 12 Q8WXH0,Q96N66,Q96G23,P30536,Q9NQC3,O94901 6 +Cellular response to leucine starvation 0.599783545608354 0.820969452234489 0.4116636685987258 1.0 0.8396137079924384 4 P42345 1 +Positive regulation of regulated secretory pathway 0.4836687651288931 0.8202606460199326 0.4120675358661745 1.0 0.8396137079924384 7 Q9NRA0,P11279 2 +Regulation of systemic arterial blood pressure 0.4358462055326925 0.8201839125826725 0.4121112715317685 1.0 0.8396137079924384 11 P09493,P42892,P42785 3 +Maintenance of protein location in mitochondrion 0.7370316007191828 0.8199904578608539 0.4122215469060966 1.0 0.8396137079924384 3 P30536 1 +Lymphocyte apoptotic process 0.3897400192260158 0.8197082835606206 0.4123824266440894 1.0 0.8396137079924384 15 P24390,Q9HCL2 2 +Striated muscle adaptation 0.5992866159473552 0.8188934719597358 0.4128471947555034 1.0 0.8396137079924384 4 P23634,P16615 2 +Alpha ketoglutarate transport 0.7361150267831824 0.8170789687815799 0.413883300877349 1.0 0.8401148934296766 2 Q9BQT8 1 +Phosphate ion transmembrane transport 0.736040609137039 0.8162987501405088 0.4143292890717847 1.0 0.840284839415704 3 Q02978,Q9UBX3 2 +Phosphate ion transport 0.736040609137039 0.8162987501405088 0.4143292890717847 1.0 0.840284839415704 3 Q02978,Q9UBX3 2 +Acute inflammatory response 0.5576218060232323 0.8155374961176773 0.4147647105820233 1.0 0.8406494611704061 5 P15291,Q9BQE5,P42785 3 +Intracellular sterol transport 0.4349586089087823 0.8148969554750004 0.4151312960347186 1.0 0.840658760121835 11 Q9H2C2,Q9P260,P61916,P22307,O15118 5 +Ketone biosynthetic process 0.4507289844520105 0.8148313656305627 0.4151688443203214 1.0 0.840658760121835 10 Q14849,Q96D53,O75208 3 +Organelle disassembly 0.3428692417785157 0.8146362217285382 0.4152805704174915 1.0 0.840658760121835 61 Q9BWH2,P27544,P12235,P53365,Q16543,Q99623,Q9Y3D6,P52789,Q96HY6,P04062,P30536,O00429,P21796,Q9UII2,P05141,Q9H300,Q13190 17 +Negative regulation of bmp signaling pathway 0.52068216641579 0.8117673039444476 0.4169251665757914 1.0 0.8416269705138804 6 Q05D32,Q8N0X7 2 +T cell mediated immunity 0.434271246979153 0.8108052424290938 0.4174775234339329 1.0 0.8416269705138804 11 P04439,Q9NUQ9,O15400 3 +Chorion development 0.7344234564420427 0.8104619631963014 0.4176747177132927 1.0 0.8416269705138804 2 Q15363 1 +Extraembryonic membrane development 0.7344234564420427 0.8104619631963014 0.4176747177132927 1.0 0.8416269705138804 2 Q15363 1 +Osteoclast differentiation 0.4497398518171939 0.8092083829793574 0.4183952938132913 1.0 0.8418470636710729 10 Q15904,P42345,Q86WC4 3 +Bicarbonate transport 0.7340079974512538 0.8087366326592657 0.418666652156674 1.0 0.8418470636710729 3 Q9Y6M7 1 +Phosphatidylinositol acyl chain remodeling 0.7340000932920534 0.8087072523389689 0.4186835556132096 1.0 0.8418470636710729 3 Q96N66 1 +Regulation of immune effector process 0.33143878883519 0.8079786250442262 0.419102887136539 1.0 0.8424326676946873 49 Q08722,P46108,Q12846,Q99623,P09601,P04439,P11279,Q9NUQ9,Q9NRA0,O15400,Q07021,Q06481,O96028,Q96FV9 14 +Arf protein signal transduction 0.5962382066799071 0.8061761896455819 0.42014126565449 1.0 0.8437044362564671 4 O95819,Q92538 2 +Plasma membrane tubulation 0.554773560684187 0.8029137496454104 0.4220245882756104 1.0 0.8457208156882052 5 Q9Y371,P50570 2 +Cytoplasm organization 0.7320924985899535 0.8016226233485698 0.422771286944829 1.0 0.8467012040913947 3 Q8N2A8,Q9Y2W6 2 +Negative regulation of amyloid precursor protein catabolic process 0.4551331084306929 0.7999079435203239 0.4237641350998131 1.0 0.8475356875263688 8 O95197,Q9NQC3 2 +Protein localization to extracellular region 0.3421576647229366 0.7984464625801259 0.4246114497025302 1.0 0.847547649375885 62 Q96PC5,P61026,Q9H4A6,Q32P28,P53985,P04083,P55011,Q5T9L3,Q86YV9,Q16822,Q16836,Q8N183,P49755,Q8TBQ9,P04035,Q8N5M9,P50416,Q16850,Q12846,Q5JRA6,O95563,O00429,P27824,Q96KC8,Q9UBV2 25 +Fatty acyl coa metabolic process 0.3762323002449352 0.7959781195298002 0.4260447532199785 1.0 0.8478355043654459 17 Q9UMR5,P50897,P33897 3 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.4785452392194116 0.7937666495821528 0.4273312912942946 1.0 0.8496245171833662 7 Q92783,Q9BRG1 2 +Negative regulation of protein polymerization 0.3317336377366968 0.7920956819728454 0.4283048876822937 1.0 0.8508534236008767 29 P35611,Q9UEY8,P45880,Q13045,O15020,Q15691,Q01082,Q02790,P16949,Q9NUQ9,P35241,Q14155,Q13813 13 +T cell proliferation 0.335071411844486 0.7902555914277849 0.4293785160718504 1.0 0.8508654715892017 25 Q92542,P02786,P30825,Q9Y6D9,Q9HCL2,P04083,P04439 7 +Male sex determination 0.7285029602480961 0.787396633435723 0.4310497168901062 1.0 0.8510999663723292 2 Q9Y6R4 1 +Sex determination 0.7285029602480961 0.787396633435723 0.4310497168901062 1.0 0.8510999663723292 2 Q9Y6R4 1 +Regulation of amyloid fibril formation 0.477202308463078 0.7868394994657337 0.4313758276078872 1.0 0.8514882407494219 7 P05067,Q9UHV9,O15212 3 +Xenobiotic metabolic process 0.388933404919255 0.7836537753059706 0.4332432927519378 1.0 0.853606701622674 14 O43169 1 +Regulation of myeloid leukocyte mediated immunity 0.4133121545916882 0.7824508465544687 0.4339496616727538 1.0 0.8537502018611134 12 P09601,Q9NRA0 2 +Negative regulation of membrane potential 0.7270933182971308 0.7819271501869854 0.4342573880163898 1.0 0.8541001318731446 2 Q9Y255 1 +Protein localization to cilium 0.3791489001053503 0.7792492979606315 0.4358328752954992 1.0 0.8558802114887851 16 Q10713,Q9UPT5,Q15643,Q96A65,Q9H4M9,A0AVF1 6 +Viral protein processing 0.4443841602405433 0.7788410124420341 0.4360733752012953 1.0 0.8558802114887851 10 Q10472,P48729,Q16706,P27824 4 +Middle ear morphogenesis 0.7253344962143595 0.7766237731329315 0.4373807714940305 1.0 0.8570073984727775 3 P54802 1 +Phosphatidylglycerol biosynthetic process 0.7253243090806506 0.7765862104335061 0.4374029397756676 1.0 0.8570073984727775 3 O95674,Q9HCL2 2 +Amyloid beta formation 0.4284558292602007 0.7762817812215552 0.4375826278375418 1.0 0.8570073984727775 11 Q92542,O95197,Q9NQC3 3 +Regeneration 0.3247162499127998 0.7760604291610409 0.4377133066268666 1.0 0.8570073984727775 33 P07196,Q96G23,P09601,Q7Z4V5,P00374 5 +Positive regulation of heart rate 0.7251325013022799 0.7758790332507969 0.4378204133903804 1.0 0.8570073984727775 3 P16615 1 +Golgi to endosome transport 0.4434459626202992 0.7735357088640826 0.439205404055643 1.0 0.8581859603309459 10 Q8N2H4 1 +Positive regulation of lymphocyte mediated immunity 0.373023602852401 0.7724995107953704 0.4398186365317964 1.0 0.8585926127187681 17 P01889,P04439,P11279,Q9NUQ9,O15400,O96028 6 +Microtubule anchoring at microtubule organizing center 0.5122966683806194 0.7720402229601794 0.44009060479378 1.0 0.8586193631234911 6 Q15154,Q8TD16 2 +Phosphatidylethanolamine biosynthetic process 0.7236553802453616 0.7704374835931859 0.4410404257200886 1.0 0.8592319638805624 3 Q9HBU6 1 +Sulfate transport 0.7236322617033075 0.7703523805136462 0.4410908926209949 1.0 0.8592319638805624 3 Q02978,Q9UBX3 2 +Synaptic vesicle cytoskeletal transport 0.5114336385829126 0.767966753794206 0.4425069368017833 1.0 0.8602291777682772 6 O95295,Q9Y2T2 2 +Negative regulation of protein secretion 0.4426813073698959 0.7656481838685464 0.4438856661215453 1.0 0.8611905681656057 9 Q8N5M9,Q16850,Q16836 3 +Retina homeostasis 0.5857375936983542 0.7626201419898205 0.4456899687196451 1.0 0.8641812866359393 4 P51790 1 +Neutrophil migration 0.3766727974188639 0.7616394041755883 0.4462752502003522 1.0 0.8647913791798766 16 Q8N5M9,P35613,O00429 3 +Positive regulation of smoothened signaling pathway 0.4415486987489366 0.759331009595709 0.4476545720631779 1.0 0.8653741751542426 9 P16435,Q96J42 2 +Cellular response to chemical stress 0.3494924954620081 0.7585347970379762 0.4481308898461726 1.0 0.8654481931890426 88 P33897,Q969S3,P09601,P00374,Q9BPX6,P07237,P04062,Q15118,O95202,P16615,Q9NP80,Q07820,Q7Z2K6,Q6NUK1,Q9NR28,Q8N0U8,Q99720,P30536,P33527 19 +Thrombin activated receptor signaling pathway 0.720890893712997 0.7579678071296329 0.4484702553226465 1.0 0.8654481931890426 2 P16949 1 +Central nervous system development 0.2458081828532786 0.7558317604983799 0.4497500717823066 1.0 0.8666281181786777 202 Q8WXH0,Q15154,Q5KU26,O14949,O75787,P50897,Q9NP58,Q16880,P62258,Q9NQC3,P05067,P23634,P07196,Q5T9L3,P51648,O15020,P98164,P04062,P54802,Q15058,Q07954,P46379,P20020,Q9H6E4,Q96QD8,O14773,O75503,Q15375,Q9UID3,P51812,O75312,O15031,Q15022,Q96D53,O75569,Q14203,P42345,P08670,Q92542,P46108,Q96N66,Q16352,Q04656,Q86XL3,Q9BSJ2,Q9BRK5,Q9Y320,Q9NRA0,Q06481,O94901,P24539 51 +Regulation of cartilage development 0.4711589214350418 0.7557623885626404 0.44979167079526 1.0 0.8666281181786777 7 P16435,Q8N5W9 2 +Regulation of tube size 0.3846067327242209 0.7543879917068274 0.4506162800188078 1.0 0.8675946351533076 14 Q9HB40,P42892 2 +Lipopolysaccharide mediated signaling pathway 0.4397650366790898 0.7527653231174524 0.4515909481755384 1.0 0.8677602436946057 10 Q86UE4 1 +Nls bearing protein import into nucleus 0.4403554066844833 0.7526826910019883 0.4516406136664395 1.0 0.8677602436946057 9 Q7Z3B4,P52292 2 +Regulation of deacetylase activity 0.7194812517620487 0.7525474006939118 0.4517219356876256 1.0 0.8677602436946057 2 Q9NRA0 1 +Eye photoreceptor cell differentiation 0.5431354501590271 0.7516372122297174 0.4522692585636405 1.0 0.8679652215970821 5 P54802 1 +Arachidonic acid secretion 0.7181382262694627 0.7501843772733863 0.4531436666345716 1.0 0.8684146326144893 3 Q9NP80 1 +Ribonucleoside triphosphate biosynthetic process 0.3249023537007335 0.749599053541058 0.453496221032762 1.0 0.8684146326144893 31 P56385,O75746,O75964,P00403,P00846,Q9NRA0,P06576,P24539 8 +Guanine nucleotide transmembrane transport 0.5825680706568244 0.7495552442043601 0.4535226146618221 1.0 0.8684146326144893 4 O15439,Q8TDW0 2 +Guanine nucleotide transport 0.5825680706568244 0.7495552442043601 0.4535226146618221 1.0 0.8684146326144893 4 O15439,Q8TDW0 2 +Semaphorin plexin signaling pathway 0.5425996307815268 0.7492891645973698 0.4536829371542321 1.0 0.8684146326144893 5 P42892 1 +Fucose metabolic process 0.7176669566383196 0.7484597370547408 0.4541829020654389 1.0 0.8688658949634646 3 Q9BTY2 1 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.7162111846888616 0.7431377098364935 0.4573983109906125 1.0 0.8710994749777031 3 Q99538 1 +Regulation of nucleotide metabolic process 0.3630505020555987 0.7431271877565863 0.457404680749558 1.0 0.8710994749777031 19 O75746,P00403,Q15118,Q9NRA0,P05067,Q9NQ88 6 +Regulation of sulfur metabolic process 0.7154540327129061 0.7403729950399204 0.4590737001706948 1.0 0.8713201466900204 3 O75027,Q15118 2 +Negative regulation of glial cell proliferation 0.7151465447189705 0.7392508611155716 0.4597546817254581 1.0 0.8713201466900204 3 Q96G23 1 +Multicellular organism aging 0.3945263264279468 0.7384621074873471 0.4602336853657707 1.0 0.8713201466900204 13 O75844 1 +Vasoconstriction 0.5399838918881259 0.7378438553138563 0.4606093399830127 1.0 0.8713201466900204 5 P42892 1 +Hypoxia inducible factor 1alpha signaling pathway 0.7152523259091974 0.7363436509907043 0.4615215877224532 1.0 0.8713201466900204 2 Q15118 1 +Regulation of acyl coa biosynthetic process 0.7152523259091974 0.7363436509907043 0.4615215877224532 1.0 0.8713201466900204 2 Q15118 1 +Potassium ion transport 0.3476680333583049 0.7355623771249302 0.4619970658894383 1.0 0.8713201466900204 22 P46934,P50570,Q96PU5,Q9NUT2,P55011,P05023,P62258 7 +Regulation of extrinsic apoptotic signaling pathway 0.319088279127998 0.7355551921375959 0.4620014398943328 1.0 0.8713201466900204 34 P30153,P06756,Q12846,P09601,P30154,P61289,Q9NQX7,Q07820 8 +Cholesterol storage 0.714104777619603 0.7354518812831541 0.4620643350011972 1.0 0.8713201466900204 3 Q8WTV0 1 +Anatomical structure maturation 0.3155449600640428 0.7350746542195407 0.4622940294414632 1.0 0.8713201466900204 36 P30153,Q9NZJ7,P04062,Q8N2A8,Q15125,O75787,Q9Y2W6,P05067,O75503,Q8N5W9,Q12768 11 +Regulation of nik nf kappab signaling 0.3678729840391244 0.7349749201001549 0.4623547684275766 1.0 0.8713201466900204 17 P05067,O43657,O43707 3 +Regulation of epithelial cell apoptotic process 0.4368233040637408 0.7330497079588243 0.4635281123227959 1.0 0.8726085707093441 9 P09601 1 +Endothelial cell migration 0.3133768744970467 0.7324959468698219 0.4638659156924394 1.0 0.8726088620242112 37 P42785,P57105,P09601,Q8WTV0,P23634,P06576,Q99538 7 +Positive regulation of protein localization to membrane 0.3152619517249717 0.7321365032175002 0.4640852555842281 1.0 0.8726088620242112 36 O14737,Q12846,Q9Y3D6,O00264,Q07954,Q01082,O15258,Q9HD47,P27105,P23634 10 +Epithelial cell proliferation 0.3197937744941272 0.729751819380198 0.4655418999431968 1.0 0.8727651555454258 45 Q92542,Q9Y366,P15291,P57105,Q99623,Q04656,P09601,Q9H2J4,Q8WTV0,Q9NQC3,Q9UII2,Q15418 12 +Regulation of atp biosynthetic process 0.4659538188178365 0.7291325629370657 0.4659205775334922 1.0 0.8730369340278572 7 O75746,P00403 2 +Regulation of protein neddylation 0.5774299108056564 0.728463319779707 0.4663300144645608 1.0 0.8731308404094458 4 Q9BTE7 1 +Glucosylceramide metabolic process 0.7120570844684126 0.7279973718886289 0.466615195083718 1.0 0.8731308404094458 3 P04062 1 +Cellular hyperosmotic response 0.5376862629778238 0.7278147478038237 0.4667269954558701 1.0 0.8731308404094458 5 O95202 1 +Endocytic recycling 0.3249402729720843 0.7275322288761571 0.4668999795833999 1.0 0.8731308404094458 29 O43752,Q15904,Q8N1B4,Q9UID3 4 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3717675861095698 0.7268930571050636 0.4672914706731368 1.0 0.873614554467658 16 Q92896,P98164,Q05D32,Q07954,Q8N0X7,P62942 6 +Negative regulation of receptor internalization 0.5364651832910315 0.7224942751659944 0.4699906438093149 1.0 0.8759219224522141 5 Q8IZ07,O00560 2 +Reticulophagy 0.4645016640719825 0.7217275498268552 0.4704620005366826 1.0 0.8763971425131653 7 O94874,Q96HY6,Q9Y6I9 3 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.3755928431134696 0.7216460247367991 0.4705121347444103 1.0 0.8763971425131653 15 P46934,Q9HD42,Q8WUX9,Q92783,Q9Y3E7,Q9BRG1 6 +Regulation of monocyte chemotaxis 0.575592893753835 0.7209499407386741 0.4709403147100763 1.0 0.8768311830629432 4 Q99538,P09429 2 +Regulation of biomineralization 0.4340796431179509 0.7208337720939011 0.4710117940947815 1.0 0.8768311830629432 10 O75844,Q8N5W9,P20020 3 +Glycerol ether metabolic process 0.463521159619347 0.7167339226981415 0.4735382902892169 1.0 0.8781714632022143 7 O15228,Q6IAN0,Q8WVX9,Q6PIU2,P49327 5 +Blastoderm segmentation 0.7088914161542317 0.7165068765401651 0.4736784229545803 1.0 0.8781714632022143 3 Q8N2A8 1 +Tripartite regional subdivision 0.7088914161542317 0.7165068765401651 0.4736784229545803 1.0 0.8781714632022143 3 Q8N2A8 1 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.7093318297152412 0.713808606287407 0.4753455371786819 1.0 0.878384123692331 2 Q15043 1 +Cerebellar purkinje cell layer formation 0.7081218274111551 0.7137198312977975 0.4754004410536854 1.0 0.878384123692331 3 P04062,Q04656 2 +Hindbrain development 0.3134165430164778 0.7132047642210921 0.4757190586273503 1.0 0.878384123692331 41 Q5T9L3,Q5KU26,P04062,P54802,O14949,Q96D53,Q9BRK5 7 +Fatty acid derivative biosynthetic process 0.3696626109675238 0.7120439071117953 0.4764375874332334 1.0 0.8791411046730349 16 Q9UJ14,P50897,Q9UMR5 3 +Vesicle organization 0.3410496781711355 0.7086524420825392 0.4785401841978702 1.0 0.8801401967643449 112 Q9BZG1,Q9H267,Q9H4A6,O14653,Q13637,Q9NP58,Q15363,Q9BRG1,O95721,Q9BXS5,Q9HD42,P62820,O60499,O15400,Q86Y82,O95295,O95249,P49755,Q9BTU6,Q9NR31,P61020,Q9P0T7,Q13190,Q12846,Q5JRA6,O43752,O00560,Q969M3,P78537,P51790,Q9BSR8,Q9Y3E7,Q14108,O14964,Q96ED9,Q12768 36 +Forebrain regionalization 0.7079221877643092 0.7084698885954528 0.4786535049592921 1.0 0.8801401967643449 2 P62995 1 +Skeletal system development 0.3291175692846313 0.7084353387670326 0.4786749535443491 1.0 0.8801401967643449 56 P51812,O75844,Q92896,Q9NX62,P16435,Q96HY6,O95470,Q32P28,Q15043,Q15125,Q15904,O96028,Q8N5W9,Q7RTS9 14 +Regulation of skeletal muscle cell differentiation 0.7061477721376195 0.7065824085826016 0.479826024117258 1.0 0.8801401967643449 3 Q92841,Q9BYT8 2 +Retinal metabolic process 0.7060557538347282 0.7062501155073784 0.4800326095435752 1.0 0.8801401967643449 3 Q6UX07 1 +Lysosomal membrane organization 0.7070764025937463 0.7052717245969408 0.4806411532177175 1.0 0.8801401967643449 2 Q9Y3E7 1 +Protein localization to nuclear envelope 0.4373463500529738 0.7031771841433427 0.4819453360853263 1.0 0.8801401967643449 8 Q7Z3B4,Q5JTV8,P53350 3 +Chaperone mediated autophagy 0.4373372831205537 0.7031283263458076 0.4819757807491971 1.0 0.8801401967643449 8 P10619 1 +Dolichol metabolic process 0.7062306174231759 0.7020773963903657 0.4826308978219411 1.0 0.8801401967643449 2 Q9H3H5 1 +Polyprenol metabolic process 0.7062306174231759 0.7020773963903657 0.4826308978219411 1.0 0.8801401967643449 2 Q9H3H5 1 +Positive regulation of atp biosynthetic process 0.5707707155484305 0.7012996307699525 0.4831160441094544 1.0 0.8801401967643449 4 P00403 1 +Positive regulation of nucleotide biosynthetic process 0.5707707155484305 0.7012996307699525 0.4831160441094544 1.0 0.8801401967643449 4 P00403 1 +Regulation of blood brain barrier permeability 0.7044557247603005 0.7004780504530632 0.4836288081353721 1.0 0.8801401967643449 3 Q16625,Q07157 2 +Positive regulation of blood brain barrier permeability 0.7044557247603005 0.7004780504530632 0.4836288081353721 1.0 0.8801401967643449 3 Q16625,Q07157 2 +Positive regulation of vascular permeability 0.7044557247603005 0.7004780504530632 0.4836288081353721 1.0 0.8801401967643449 3 Q16625,Q07157 2 +Magnesium ion homeostasis 0.7041410662986155 0.6993442491718942 0.4843369199723719 1.0 0.8804543733162771 3 Q8NE01 1 +Neuron death 0.3433471662182619 0.6961630107670075 0.4863267494061394 1.0 0.8825609524748675 83 P07196,Q9NR28,O75312,Q96A26,Q01105,P09601,P04062,Q99720,Q15392,P50897,O76024,P05067,Q07820,Q4ZIN3 14 +Insulin processing 0.7030456852791725 0.695400708126736 0.4868042168988185 1.0 0.8828719656194174 3 Q8TAD4,Q969M3 2 +Protein folding in endoplasmic reticulum 0.4296635990084439 0.6934801767230284 0.4880082619020127 1.0 0.8838208159516493 9 P07237,P27824,P14625,Q13217,Q8IXB1 5 +Regulation of phospholipid metabolic process 0.3984085097745022 0.6904273928468879 0.4899254553013343 1.0 0.884449612192967 12 Q99758,Q8WTV0,Q8NF37,Q99623 4 +Regulation of neurotransmitter uptake 0.5674523997189939 0.6878409017074611 0.4915529758961261 1.0 0.8864666636876396 4 O75955,P05556 2 +Negative regulation of epithelial cell apoptotic process 0.457540936876795 0.6863923566291102 0.4924657230547997 1.0 0.8867127416199645 7 P09601 1 +Transforming growth factor beta production 0.5663660247049945 0.6834463245923108 0.4943248563270472 1.0 0.888604019411086 4 P06756 1 +Cop9 signalosome assembly 0.6993795826283147 0.6822414241873473 0.4950863051219794 1.0 0.8891114067196231 3 Q99627,Q9H9Q2 2 +Protein deglycosylation 0.4334387314210629 0.6821693684339588 0.495131861321489 1.0 0.8891114067196231 8 O00754,O60476,Q86TM6 3 +Regulation of alternative mrna splicing via spliceosome 0.3190461597690729 0.6816961663535972 0.4954310920733804 1.0 0.8891114067196231 30 P52756,P51116,P51114,Q9UHX1,P98175,Q06787 6 +Regulation of transport 0.2747825104372349 0.6816763358904628 0.4954436340340016 1.0 0.8891114067196231 350 Q15154,P06756,O43707,P52789,P09601,Q03164,P11233,P50897,P46934,Q9HD47,Q9P2W9,P22413,P62942,Q7L0J3,P57105,Q99623,P50416,Q14012,P21796,P49257,Q9UII2,O75844,O14737,Q12846,Q13438,Q92544,Q00765,P08183,P61026,Q12907,Q9H4A6,Q05D32,P53985,Q8TAD4,P51572,P05023,Q08431,Q9H2C2,Q5T9L3,Q07954,Q8WTV0,P27105,Q9C0E2,O75955,O95295,Q16822,Q96PU5,Q8N5M9,P61020,Q08722,Q16850,Q9GZP9,Q04656,Q9Y282,Q13586,O95563,Q969M3,Q96KC8,Q9Y3E7,O14964,P62258,P50570,Q32P28,Q9Y255,P04083,O76024,P05067,P55011,P60604,O15260,Q9BRK0,P12270,P05026,O95429,Q9H4M9,P61978,O75312,P50402,Q8N183,P11279,Q9H300,Q16625,Q9Y3D6,P30536,Q9NV96,Q8WVM8,P23634,Q7Z3B4,P20020,Q06787,P05141,Q9Y371,Q8IZ07,Q16836,P16615,P49755,P04035,Q9NR31,O00429,O00560,Q99758,Q9NRA0,Q06481 103 +Response to calcium ion 0.3228937743772943 0.680084339983371 0.496451059557391 1.0 0.8904168581153423 25 Q6NUK1,Q92542,P46934,O75746,Q13586,Q86YQ8 6 +Amyloid beta metabolic process 0.385046573109372 0.6777476918324477 0.4979316819497272 1.0 0.8912318235285348 13 Q92542,O95197,Q9NQC3 3 +Peptide transport 0.3205687167715876 0.6776507971506277 0.4979931301868965 1.0 0.8912318235285348 28 Q16822,Q16836,Q12846,O95563,P62820,P53985,Q8N5M9,Q03518,P04083,P50416,P33527,O15439 12 +Multivesicular body sorting pathway 0.3846652504671419 0.6753212064226681 0.4994717135884889 1.0 0.8916243680714088 13 Q9HD42,Q8WUX9,Q92783,Q9Y3E7,Q9BRG1 5 +Endosome transport via multivesicular body sorting pathway 0.3846652504671419 0.6753212064226681 0.4994717135884889 1.0 0.8916243680714088 13 Q9HD42,Q8WUX9,Q92783,Q9Y3E7,Q9BRG1 5 +Er associated misfolded protein catabolic process 0.4915695234778926 0.6751331819350522 0.4995911536863184 1.0 0.8916243680714088 6 Q9BUN8 1 +Regulation of smad protein signal transduction 0.5642424854290552 0.6748732492359572 0.49975629750509 1.0 0.8916243680714088 4 Q07954,Q8N1F7 2 +Positive regulation of smooth muscle cell migration 0.5638515210041215 0.6732973500276667 0.5007581383278952 1.0 0.8921850375186601 4 P46108 1 +Complement activation 0.6967873212859516 0.6729739473716392 0.5009638655247699 1.0 0.8921850375186601 3 Q07021 1 +Regulation of humoral immune response 0.6967873212859516 0.6729739473716392 0.5009638655247699 1.0 0.8921850375186601 3 Q07021 1 +Regulation of complement activation 0.6967873212859516 0.6729739473716392 0.5009638655247699 1.0 0.8921850375186601 3 Q07021 1 +Mitotic nuclear membrane organization 0.4909789160000102 0.6724033286104673 0.5013269643184199 1.0 0.8925899957558873 6 Q6NUK4,Q9H6H4 2 +Positive regulation of neural precursor cell proliferation 0.4905718688015523 0.6705230397504056 0.5025244242343483 1.0 0.8938665551385196 6 P55209 1 +Ventricular cardiac muscle tissue development 0.4253468298031877 0.6697843905825883 0.5029952455750708 1.0 0.8939310387610649 9 O75844,P09493,P62942 3 +Heparin metabolic process 0.6974908373273245 0.6693010979434799 0.5033034265671619 1.0 0.8939310387610649 2 O94923 1 +Heparin biosynthetic process 0.6974908373273245 0.6693010979434799 0.5033034265671619 1.0 0.8939310387610649 2 O94923 1 +Regulation of phosphatidylinositol 3 kinase signaling 0.4246663147930798 0.6660608234933274 0.5053722240355145 1.0 0.896088174288197 9 P46934 1 +Pancreas development 0.424590317200706 0.6656451962913593 0.5056379105873314 1.0 0.8961413467887036 9 Q5T9L3 1 +Mrna 3 splice site recognition 0.522872948845968 0.6637531424313392 0.5068483204221086 1.0 0.8965426424994191 5 Q15459,Q12874,Q15637 3 +Maintenance of location 0.3373125698621168 0.6634821104268602 0.5070218332235525 1.0 0.8965426424994191 74 P06756,P52789,P24390,Q9UH99,O15258,P17900,P04062,Q14534,O43292,P22413,Q8WTV0,O95202,P62942,P10253,Q96RL7,O43731,Q9H6V9,Q13438,P30536 19 +Postsynaptic cytoskeleton organization 0.5611479395918275 0.6624213594732757 0.5077012185805807 1.0 0.8965426424994191 4 P07196 1 +Calcium mediated signaling 0.3488389274188616 0.6623590666945227 0.5077411304499777 1.0 0.8965426424994191 20 O75844,Q9Y3D6,P16615,P23634,P42345 5 +Cellular hyperosmotic salinity response 0.5611201401297048 0.662309725981126 0.5077727449156662 1.0 0.8965426424994191 4 O95202 1 +Hyperosmotic salinity response 0.5611201401297048 0.662309725981126 0.5077727449156662 1.0 0.8965426424994191 4 O95202 1 +Cellular response to salt stress 0.5611201401297048 0.662309725981126 0.5077727449156662 1.0 0.8965426424994191 4 O95202 1 +Hydrogen peroxide biosynthetic process 0.6932945727836692 0.6605375167069284 0.508908951227204 1.0 0.8973441313707631 3 P00403 1 +Regulation of collateral sprouting 0.6931754089114384 0.6601142551089237 0.5091805114495589 1.0 0.8973441313707631 3 Q15375,Q8N0X7 2 +Signal transduction in absence of ligand 0.3622540113128736 0.6601123418751338 0.5091817391326878 1.0 0.8973441313707631 16 Q07820,P30153,P06756,P30154 4 +Regulation of golgi organization 0.4290117560516633 0.6584932561296662 0.5102212290518651 1.0 0.8981346165843073 8 Q9P2W9,Q13190 2 +Behavior 0.3395096028891277 0.6579252202070621 0.510586183884556 1.0 0.8981346165843073 81 Q15154,O00264,P53985,P50897,O76024,P05067,P17900,O15020,P04062,P54802,O15118,Q96KQ7,Q99538,P10253,Q96RL7,P04035,P50416,Q14203,P42345,O75844,Q92542,Q9GZP9,P30536,P51790 24 +Negative regulation of autophagosome assembly 0.6922919532633525 0.6569784491039864 0.5111947737135925 1.0 0.8981594656308322 3 Q8WVM8 1 +Sperm motility 0.5212678588047757 0.656879384756512 0.5112584747262443 1.0 0.8981594656308322 5 Q96RL7 1 +Cardiolipin metabolic process 0.4284313831738844 0.6553996041171789 0.512210506315681 1.0 0.8981594656308322 8 Q9NP80,Q99623 2 +Unsaturated fatty acid biosynthetic process 0.3925653894330529 0.6548088860305198 0.5125908087233815 1.0 0.8981594656308322 12 P33897,Q9H7Z7,P04083,Q8NCG7,Q9NP80,O60427 6 +Establishment of pigment granule localization 0.6912013536378973 0.6531126863867822 0.5136836341409707 1.0 0.8981594656308322 3 P62820,Q13561 2 +Odontogenesis 0.407374481929895 0.6528742279894548 0.513837364980636 1.0 0.8981594656308322 11 Q13586,P35613 2 +Extrinsic apoptotic signaling pathway via death domain receptors 0.3611756036306613 0.6525997806929726 0.5140143269932267 1.0 0.8981594656308322 16 P09601 1 +Glycoside metabolic process 0.4219619216625943 0.6512968647142809 0.5148548719092143 1.0 0.899112762708088 9 Q9BTY2,P06280,P04062 3 +Response to dietary excess 0.6902779616442423 0.6498442253820491 0.5157928484975207 1.0 0.8993556639894469 3 Q96E52 1 +T cell differentiation in thymus 0.4210531188721507 0.6484636310914753 0.5166851262991741 1.0 0.8997188444981911 10 O96005 1 +Protein polyufmylation 0.5570757291524903 0.646112859360063 0.5182062679636243 1.0 0.900936458999936 4 O94874,Q96HY6 2 +Mitochondrial depolarization 0.4487884439955142 0.6423751886785052 0.5206296054838084 1.0 0.9030012962202024 7 P30536,P33897 2 +Regulation of aerobic respiration 0.3677903890817459 0.6420808175807259 0.5208207101846811 1.0 0.903094598176812 14 P14406,Q9BSK2 2 +Positive regulation of epithelial cell proliferation 0.3307019099341995 0.6414985439582545 0.5211988265983327 1.0 0.9032739611428812 23 P09601,Q9H2J4 2 +Mitochondrion morphogenesis 0.4194643062582504 0.6397222102639823 0.5223532133592497 1.0 0.9040146246485168 10 Q04837,Q9GZY8,O00429,Q9Y3D6 4 +Leukocyte mediated immunity 0.321820555467012 0.6390966679548453 0.5227600474205172 1.0 0.9040146246485168 55 P46108,Q12846,P09601,Q99584,Q8N5M9,P04439,P11279,Q9NUQ9,Q9NRA0,O15400,Q07021,O96028,Q96FV9 13 +Second messenger mediated signaling 0.3170671439451945 0.638308671394506 0.523272768404691 1.0 0.9040146246485168 27 O75844,P30153,Q9Y3D6,P16615,P23634 5 +Tooth mineralization 0.5549332971458225 0.6375693228072022 0.5237540704678447 1.0 0.9043661122255224 4 Q13586 1 +Neutral lipid metabolic process 0.3517956207351036 0.6359371501673006 0.5248173874752498 1.0 0.9045601108489648 18 Q96N66,Q8NCC3,Q92604,Q9HCL2,P50416,Q8NCG7,Q8WTV0,Q9UBV2,Q9NUQ2 9 +Sterol transport 0.3151452471961524 0.6354345181687154 0.5251450613044315 1.0 0.9045601108489648 29 Q9H2C2,P61916,P30536,Q07954,Q99758,Q9BZF1,Q14849,Q6IAA8,Q8WTV0,O15118,Q86Y82 11 +Apoptotic process involved in development 0.4473691721618407 0.6352851306041079 0.5252424696243643 1.0 0.9045601108489648 7 P30154 1 +Negative regulation of adaptive immune response 0.68790527206088 0.6338670193533232 0.5261676108109168 1.0 0.904845203962318 2 Q96FV9 1 +Biological process involved in intraspecies interaction between organisms 0.4824646386859492 0.6332734192044561 0.526555108145327 1.0 0.904845203962318 6 Q96RL7 1 +Alanine transport 0.6876233436707161 0.6328334246181669 0.5268424270451137 1.0 0.9049471513908888 2 Q96QD8 1 +Folic acid containing compound metabolic process 0.3625083985182689 0.6324480916702863 0.5270941173139065 1.0 0.9051430834395726 15 P00374 1 +Regulation of phosphatidylcholine metabolic process 0.482015803304645 0.6312228223942524 0.527894841462027 1.0 0.9060449823318768 6 Q8WTV0,Q8NF37 2 +Interleukin 12 production 0.4461815985605138 0.6293633607963999 0.5291111991020565 1.0 0.9065436716426792 7 Q08722,Q07021 2 +Sodium ion export across plasma membrane 0.6841511562323658 0.6282673768641401 0.5298287989078498 1.0 0.9072335356461672 3 P05026,P05023 2 +Hematopoietic stem cell homeostasis 0.551687606623712 0.6246759292876832 0.5321837743528375 1.0 0.9075225993921028 4 Q9NX40 1 +Response to mineralocorticoid 0.4798036105857086 0.6211346944484835 0.5345110033884688 1.0 0.9098030200015422 6 P07196 1 +Negative regulation of mrna processing 0.3433946312284055 0.6203858114165379 0.535003811460923 1.0 0.9104062271613172 20 P61978,P26368,P98175,Q07021,P38159,O75150 6 +Granulocyte differentiation 0.4441589230689982 0.6193006508662381 0.5357183157706782 1.0 0.9106437442207322 7 Q8N5M9 1 +Membrane repolarization 0.4155975835729782 0.6167767584259485 0.5373819839184555 1.0 0.9110004538229364 9 O75844,Q96PU5,P05023,P62258 4 +Insulin metabolic process 0.5495947979014099 0.6163949382851635 0.5376338932560887 1.0 0.9110418257817164 4 Q8TAD4,Q969M3 2 +Bile acid and bile salt transport 0.6828305610375014 0.6153404773723521 0.5383298914281778 1.0 0.911350243480856 2 O15439 1 +Paranodal junction assembly 0.6796390298928155 0.6125030426393157 0.5402049855483653 1.0 0.91168998933961 3 O15228,Q16880 2 +Negative regulation of mitochondrial fusion 0.5478039292932229 0.6093295199665909 0.542306044030981 1.0 0.9127039728768044 4 Q96E52 1 +Intracellular mrna localization 0.6808570623061775 0.6081812467890869 0.5430672709985125 1.0 0.9132583588231186 2 Q99729 1 +Establishment of mitochondrion localization 0.3993955148641831 0.6070647718854811 0.5438079277889092 1.0 0.914036478678164 11 Q9UBK9,O60313 2 +Regulation of the force of heart contraction 0.5090116678443484 0.6048848099474418 0.5452555367680652 1.0 0.9151022049995152 5 P10253,P23634,P16615 3 +Endosomal transport 0.3362441419123426 0.6037146464870657 0.5460333747539521 1.0 0.9151022049995152 87 Q96D71,P61026,Q8N1B4,Q9H223,Q9UQN3,Q92783,Q9BRG1,Q6IAA8,O15260,Q9HD42,Q9C005,O60499,Q9H4M9,O75503,Q8IUD2,Q4J6C6,Q9UID3,P61106,P42566,O60271,O95249,Q9Y5X3,O60749,Q8NBN3,O15498,P51151,Q14203,P49257,Q13190,Q8WUX9,O43752,Q9UNH7,P78537,Q92538,P40616,Q15904,Q9Y3E7,Q96L92,O14964,O60826 40 +Protein import into peroxisome membrane 0.676818950930616 0.6027067363650558 0.5467037994131378 1.0 0.9151022049995152 3 P56589,P40855 2 +Photoreceptor cell maintenance 0.6767444991119842 0.6024487078725416 0.5468754959683577 1.0 0.9151022049995152 3 P51790 1 +Metencephalon development 0.3041053818683197 0.600670398819436 0.5480595386183809 1.0 0.9151022049995152 35 Q5KU26,P04062,P54802,O14949,Q96D53,Q9BRK5 6 +Regulation of phospholipase c activity 0.6780377784042799 0.5979992012831623 0.5498404660237663 1.0 0.916232973839594 2 Q99623 1 +Activation of phospholipase c activity 0.6780377784042799 0.5979992012831623 0.5498404660237663 1.0 0.916232973839594 2 Q99623 1 +Activation of protein kinase c activity 0.6780377784042799 0.5979992012831623 0.5498404660237663 1.0 0.916232973839594 2 Q99623 1 +Cellular response to virus 0.3196716335431436 0.5972183155840409 0.5503616323860121 1.0 0.916232973839594 24 O43657,Q9NUD5,Q99623,Q86UT6,Q06787,Q07021 6 +Mitochondrial ribosome assembly 0.5070848779423791 0.596795206133696 0.5506441189532163 1.0 0.916232973839594 5 Q567V2 1 +Glycolytic fermentation 0.674850907715644 0.5958965805884214 0.5512443176954955 1.0 0.916232973839594 3 O75746 1 +Fermentation 0.674850907715644 0.5958965805884214 0.5512443176954955 1.0 0.916232973839594 3 O75746 1 +Glycoprotein catabolic process 0.6771919932337225 0.5949551667222261 0.5518734398840095 1.0 0.9165286902218356 2 O60502 1 +Positive regulation of stress activated protein kinase signaling cascade 0.3606025278592939 0.5949403189992271 0.551883365052066 1.0 0.9165286902218356 14 P05067,Q969S3 2 +Positive regulation of endothelial cell migration 0.3352833554420577 0.5936467745361546 0.5527483893249407 1.0 0.9166480475517236 21 P09601,P06576,Q8WTV0 3 +Apical protein localization 0.5062076749435518 0.5931203433360845 0.5531006168218131 1.0 0.9170009470221993 5 Q9HD26,Q9BX67,P35241,P54920 4 +Centromere complex assembly 0.3822529794719315 0.5927223264792196 0.5533669971643587 1.0 0.917086849483013 12 Q9BS16,P49321 2 +Icosanoid biosynthetic process 0.37121833354843 0.5906684672057786 0.554742579842872 1.0 0.9174889207045728 13 Q99735,Q9H7Z7,Q9UJ14,Q8NCG7,Q9NP80,O60427 6 +Pteridine containing compound metabolic process 0.3428222567334716 0.590660569875492 0.5547478723449919 1.0 0.9174889207045728 19 P00374 1 +Regulation of membrane potential 0.3224353751201291 0.589765405441967 0.5553479387752629 1.0 0.9174889207045728 61 O75844,P33897,P46934,Q9BSK2,P16615,Q96PU5,P04062,P30536,Q9Y255,Q9HD47,Q8IWA4,Q06787,Q9UJZ1,P05067,Q9UII2,P42345 16 +Negative regulation of translational initiation 0.4378512356359023 0.5881175867921681 0.5564533693432594 1.0 0.9179751410778249 7 P60228,Q06787 2 +Negative regulation of mrna splicing via spliceosome 0.359420427356537 0.5872463353647754 0.5570382771171665 1.0 0.9179751410778249 14 P61978,P26368,P98175,Q07021,P38159 5 +Cerebral cortex cell migration 0.4094414576994138 0.5850705952189605 0.5585002496126963 1.0 0.9179751410778249 10 Q8WXH0,Q96N66,Q9NQC3 3 +Vesicle fusion to plasma membrane 0.5411808993457399 0.5833732675830656 0.559642049620114 1.0 0.9179751410778249 4 O95721,Q12846 2 +Regulation of spontaneous synaptic transmission 0.6711800446664774 0.5832533297703586 0.5597227751455647 1.0 0.9179751410778249 3 P05067 1 +Spontaneous synaptic transmission 0.6711800446664774 0.5832533297703586 0.5597227751455647 1.0 0.9179751410778249 3 P05067 1 +Regulation of alcohol biosynthetic process 0.6711787930062042 0.5832490321472729 0.5597256678150595 1.0 0.9179751410778249 3 P16435,O94905 2 +Regulation of cholesterol biosynthetic process 0.6711787930062042 0.5832490321472729 0.5597256678150595 1.0 0.9179751410778249 3 P16435,O94905 2 +Mitochondrial electron transport nadh to ubiquinone 0.3118801298016476 0.5821835420640303 0.5604430578143886 1.0 0.9183428482201 25 O95139,P03886,O75208,O43676 4 +Intracellular transport of virus 0.4709994603944412 0.5813106517248638 0.5610311029570263 1.0 0.9183428482201 6 P52292 1 +Cellular modified amino acid catabolic process 0.408633799887321 0.5807063024756752 0.5614384133251216 1.0 0.9187649845811208 10 Q9UHG3,Q9UJ14 2 +Negative regulation of oxidoreductase activity 0.5403080610911475 0.579973541123967 0.5619324607387053 1.0 0.9187720563632182 4 Q15070,P06280 2 +Regulation of guanyl nucleotide exchange factor activity 0.6700742160110513 0.57946002323796 0.5622788134756238 1.0 0.9190128618859784 3 Q9Y2S7 1 +Steroid hormone biosynthetic process 0.4360005415094373 0.5790279972975644 0.562570282128914 1.0 0.9192608063507746 7 P30536,Q14849 2 +Pyridine containing compound catabolic process 0.5398973742353185 0.5783756443498933 0.5630105337735665 1.0 0.9192950051213372 4 Q9BQG2 1 +Positive regulation of tau protein kinase activity 0.6718353538201364 0.575792394287209 0.5647555150043617 1.0 0.9200024172336472 2 P07900 1 +Regulation of transforming growth factor beta activation 0.6718353538201183 0.5757923942871449 0.564755515004405 1.0 0.9200024172336472 2 P06756 1 +Transforming growth factor beta activation 0.6718353538201183 0.5757923942871449 0.564755515004405 1.0 0.9200024172336472 2 P06756 1 +Cd4 positive alpha beta t cell activation 0.4351896379641133 0.5750541807087284 0.5652546546146398 1.0 0.9200024172336472 7 P42345,Q04656,Q9UJZ1 3 +Positive regulation of interleukin 1 beta production 0.469205864074705 0.5732649963296939 0.5664652820940752 1.0 0.9201388393017368 6 P05067 1 +Polyol metabolic process 0.3088701847921438 0.570099536136426 0.5686101897600317 1.0 0.9224837735697408 28 Q9BW91,Q9NX62,Q10713,P04062,Q13510,O15269,P00374 7 +Protein refolding 0.378274234920423 0.569067496631062 0.5693103352470223 1.0 0.92316421965475 12 P62942 1 +Bone maturation 0.666571299921765 0.5674921696526686 0.5703798450859194 1.0 0.9240900708284752 3 Q8N5W9 1 +Animal organ maturation 0.666571299921765 0.5674921696526686 0.5703798450859194 1.0 0.9240900708284752 3 Q8N5W9 1 +Transport of virus 0.4334366588941427 0.5664826542980225 0.5710657211204127 1.0 0.9240900708284752 7 P52292 1 +Negative regulation of map kinase activity 0.4333186352209622 0.5659064959349049 0.5714573454543044 1.0 0.9240900708284752 7 P04062 1 +Mechanoreceptor differentiation 0.4060558105013709 0.5656768502002925 0.571613475045373 1.0 0.9240900708284752 9 P54802,Q9Y6M7 2 +Negative regulation of lipase activity 0.665636147197699 0.564309742167003 0.5725433524412327 1.0 0.9240900708284752 3 P16435 1 +Astrocyte activation 0.6655898586683674 0.5641523563160872 0.572650448989471 1.0 0.9240900708284752 3 P05067 1 +Regulation of mononuclear cell migration 0.3418649700402589 0.5640808803953496 0.5726990894393968 1.0 0.9240900708284752 18 Q08722,P46108,P05067,Q07021,Q99538 5 +Epoxide metabolic process 0.6684522131378667 0.5637955279762974 0.5728932956373018 1.0 0.9240900708284752 2 P07099 1 +Striated muscle contraction 0.3312665431331267 0.5623195665670738 0.5738983094294197 1.0 0.9247573506643366 21 P16615,P10253,Q96PU5,Q9HD47,P42345 5 +Intra golgi vesicle mediated transport 0.3411203806663954 0.5587499975784433 0.5763323520850645 1.0 0.9263289050985996 18 Q8WTW3,Q96JB2,O95249,O14653,Q8TBA6,P61923,Q9UP83,P35606 8 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.6667606427967325 0.557828679393919 0.5769613768224817 1.0 0.9266605556438248 2 P49327 1 +Positive regulation of lipid transport 0.4042886910060181 0.5573367327867512 0.5772973830156789 1.0 0.9267351801031024 10 Q9Y255,Q9NV96,Q99758 3 +Negative regulation of vascular associated smooth muscle cell proliferation 0.4975519709907844 0.5571417912901419 0.5774305561901343 1.0 0.9267351801031024 5 P09601 1 +Response to oxygen levels 0.3242922217222622 0.555427444617117 0.5786023249104557 1.0 0.9268924916645626 68 O43707,P52789,P09601,Q8WVM8,P02545,P00846,P30519,Q8N511,P07237,Q9Y4P3,Q96A26,P49327,Q15118,P02786,Q99623,Q9Y487,P42345,Q92544,Q15904,Q9NQ88 20 +Negative regulation of apoptotic signaling pathway 0.3242727094110863 0.5552138606472627 0.5787483893935441 1.0 0.9268924916645626 68 Q9H3K2,P45880,Q8N2F6,P09601,Q7LG56,O60313,Q9Y255,Q9P0J0,P61289,Q86TM6,O76024,Q07820,P05141,Q9H300 14 +Mononuclear cell migration 0.3087608750785547 0.5548410555386009 0.5790033825455552 1.0 0.926936152055284 25 Q08722,P46108,Q5JRA6,Q07021,P04062,P04083,P05067,Q99538 8 +Regulation of rig i signaling pathway 0.4309863379998399 0.5545457098068594 0.579205432085093 1.0 0.926936152055284 7 Q07021,Q86UT6 2 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.6620374308135445 0.5521133384887954 0.5808707038424443 1.0 0.9277106123889816 3 Q9Y3D6 1 +Sarcoplasmic reticulum calcium ion transport 0.4304467058681415 0.5519239509467829 0.5810004580249681 1.0 0.9277106123889816 7 O75844 1 +Regulation of membrane repolarization 0.4641991640461701 0.5509350326003967 0.5816782111797938 1.0 0.9279901931520498 6 O75844 1 +Positive regulation of leukocyte mediated immunity 0.3141332413076069 0.5501269937869038 0.5822322731411076 1.0 0.9279901931520498 24 Q12846,P01889,P04439,P11279,Q9NUQ9,O15400,O96028 7 +Positive regulation of low density lipoprotein receptor activity 0.6611476415925108 0.5491102723446659 0.5829297760983643 1.0 0.9284751670603868 3 Q9Y2B0 1 +Embryonic heart tube development 0.4291365539309248 0.5455695673190868 0.5853618483068423 1.0 0.9301582209021748 7 P42892 1 +Myeloid leukocyte differentiation 0.2998887703975348 0.5443622944261128 0.5861921872305351 1.0 0.9302166098129656 34 P04062,Q8N5M9,Q15904,Q14739,P05067 5 +Regulation of osteoclast differentiation 0.6596991822333627 0.5442324546817152 0.5862815210189027 1.0 0.9302166098129656 3 P42345 1 +Nadh oxidation 0.6628136453340885 0.5439897936743243 0.586448496273599 1.0 0.9302166098129656 2 Q16822 1 +L serine transport 0.6596164692611216 0.5439543167846398 0.5864729097999799 1.0 0.9302166098129656 3 Q96QD8,Q9H9B4 2 +Ventricular cardiac muscle cell development 0.6622497885537066 0.542022530841502 0.5878029847016399 1.0 0.9302166098129656 2 P02545 1 +Ventricular cardiac muscle cell differentiation 0.6622497885537066 0.542022530841502 0.5878029847016399 1.0 0.9302166098129656 2 P02545 1 +Positive regulation of mitochondrial fission 0.4010029989936015 0.539793533588274 0.5893394270390684 1.0 0.9309045514548904 10 P11233,Q9GZY8,O00429,Q9Y3D6 4 +T helper 1 cell differentiation 0.6583506547589925 0.5397032822769762 0.5894016760472196 1.0 0.9309045514548904 3 P42345 1 +T helper 1 type immune response 0.6583506547589925 0.5397032822769762 0.5894016760472196 1.0 0.9309045514548904 3 P42345 1 +Negative regulation of response to wounding 0.4009916092540332 0.5389123395336937 0.5899473424206629 1.0 0.9310038784216176 9 P46108,Q96G23 2 +Positive regulation of protein export from nucleus 0.3731010809731216 0.5385905349933028 0.5901694199234346 1.0 0.9310038784216176 12 P50402,Q05D32,Q14012,Q9C0E2,P62258 5 +Er nucleus signaling pathway 0.3622374345281121 0.5352780947631637 0.5924575713177038 1.0 0.9314010539872613 13 P16615,Q96A33,P57088,Q15363,O76024,Q9UM00 6 +Positive regulation of cell cell adhesion mediated by cadherin 0.5286833362657535 0.5351926468277571 0.592516650430698 1.0 0.9314010539872613 4 O75955 1 +Regulation of cell cell adhesion mediated by cadherin 0.5286833362657535 0.5351926468277571 0.592516650430698 1.0 0.9314010539872613 4 O75955 1 +Cardiac muscle cell action potential 0.3621431898831546 0.5347024006308791 0.5928556612157427 1.0 0.9317112745079904 13 P16615,Q96PU5,Q9HD47,P05023,P62258 5 +Protein localization to microtubule end 0.6597124330420129 0.533200445309304 0.5938948333028762 1.0 0.9326758162925064 2 Q15691 1 +Glutamine transport 0.6594305046518201 0.5322233296820074 0.5945713266651476 1.0 0.9329746453452564 2 Q96QD8 1 +Negative regulation of g protein coupled receptor signaling pathway 0.4599423895440995 0.5321060699670369 0.5946525335696085 1.0 0.9329746453452564 6 P50570,P23634 2 +Membrane raft organization 0.4046899185265084 0.5312412111405515 0.5952516383343396 1.0 0.9331325059209808 8 P50897 1 +Regulation of calcium ion transmembrane transport 0.327193315162044 0.5308309974995238 0.5955358976969234 1.0 0.9331325059209808 21 Q13586,P21796,P62942 3 +Plasma membrane raft organization 0.6545685426392518 0.5270640327837945 0.5981491225816191 1.0 0.9335611720976054 3 O75955 1 +Plasma membrane raft assembly 0.6545685426392518 0.5270640327837945 0.5981491225816191 1.0 0.9335611720976054 3 O75955 1 +Nonribosomal peptide biosynthetic process 0.4586311781517707 0.5263364031603113 0.5986544942984264 1.0 0.9336852285987076 6 Q9UJ14 1 +Neuromuscular junction development 0.3850122654071588 0.526095453580873 0.5988218873654594 1.0 0.9337198734650004 11 P46934,O15258,Q14203,P05067,Q9Y4W6 5 +Negative regulation of organic acid transport 0.6539763113367125 0.525093467619681 0.5995182169709432 1.0 0.9337198734650004 3 O75915,Q9Y3D6 2 +Developmental maturation 0.3061191687047347 0.5250677010120572 0.5995361282962737 1.0 0.9337198734650004 50 P07196,Q9BXS5,P30153,Q9NZJ7,P04062,Q8N2A8,Q15058,P51790,Q13637,O75787,Q15125,Q9Y2W6,P05067,O75503,Q8N5W9,Q12768 16 +Long chain fatty acyl coa metabolic process 0.3980045643666738 0.5238858752762109 0.6003579195470774 1.0 0.9337878930281336 10 Q9NZ01,Q53GQ0,Q9UKU0 3 +Aorta morphogenesis 0.5253709686028832 0.5226112432515192 0.6012448147953267 1.0 0.9337878930281336 4 Q96AY3 1 +Purine ribonucleoside metabolic process 0.4029029138137507 0.5221121633503861 0.6015922381125232 1.0 0.9337878930281336 8 O60725,Q13126 2 +Regulation of synapse structure or activity 0.2930890901400114 0.5221120024133815 0.6015923501598279 1.0 0.9337878930281336 37 P05067,P46934,O00264,P50897 4 +Autophagosome maturation 0.3331458179356963 0.51968049582198 0.6032862832179073 1.0 0.9337878930281336 19 O95295,Q9HD42,Q9H267,P16615,Q8WUX9,P13473,Q9UQN3,Q9Y3E7,O95721 9 +Intraciliary transport 0.4570996822050309 0.5196159551289057 0.603331275341058 1.0 0.9337878930281336 6 Q15154,Q9Y366,A0AVF1 3 +Nik nf kappab signaling 0.3256745968257897 0.5191674118732108 0.6036440021213398 1.0 0.9337878930281336 21 P05067,O43657,Q99627,O43707 4 +Positive regulation of synaptic transmission 0.3355009225175082 0.518803531188447 0.6038977552115083 1.0 0.9337878930281336 18 Q92542,Q12846,Q06787,P05067,O75955,Q14168,Q99538 7 +Regulation of cardiac muscle cell action potential 0.4568545093481866 0.5185419739781186 0.6040801823715438 1.0 0.9337878930281336 6 Q9HD47 1 +Eosinophil activation 0.6552015787989769 0.5176426597336667 0.6047076118756198 1.0 0.9337878930281336 2 Q12846 1 +Eosinophil mediated immunity 0.6552015787989769 0.5176426597336667 0.6047076118756198 1.0 0.9337878930281336 2 Q12846 1 +Regulation of low density lipoprotein particle clearance 0.4559466712013832 0.5145697402279026 0.606853714882764 1.0 0.934101285422588 6 Q9Y2B0 1 +Leukocyte migration 0.308061580054103 0.5129486312139497 0.6079872541216753 1.0 0.934101285422588 53 Q08722,P46108,P15291,Q5JRA6,P09601,Q07021,P04062,O00429,Q8N5M9,P05067,P35613,Q99538 12 +Response to light intensity 0.6537919368480265 0.5128145789240177 0.6080810306715669 1.0 0.934101285422588 2 Q8NBN7 1 +Rig i signaling pathway 0.3686006310260173 0.512353437393981 0.6084036723847945 1.0 0.934101285422588 12 Q07021,Q86UT6,Q99623 3 +Exocytic process 0.3290460460246763 0.5118593381467467 0.6087494578589911 1.0 0.934101285422588 20 Q7L0J3,P61026,Q12846,O15498,O95721,Q7Z6M1 6 +Exocytosis 0.3275765165571814 0.5114344329917934 0.6090468891825775 1.0 0.934101285422588 84 P61026,P09601,P11233,Q9Y3C0,O95721,O15439,Q9UPT5,Q96A65,Q06787,O95295,Q7L0J3,P16615,Q92905,O43760,P49755,Q8N5M9,O15498,P11279,Q7Z6M1,Q12846,Q5JRA6,Q9BRK5,Q99584,O00560,Q9Y3E7,Q9NRA0,O14964 27 +Regulation of neurotransmitter levels 0.2997977074488124 0.5100024819312293 0.6100497229954336 1.0 0.934101285422588 31 Q7L0J3,Q12846,P16615,P21964,P50897,Q8NCG7,Q06787,O95721,O75955 9 +Positive regulation of insulin secretion involved in cellular response to glucose stimulus 0.5215553523626588 0.508222508380998 0.6112973075031063 1.0 0.934101285422588 4 Q12846 1 +Regulation of potassium ion transport 0.3469659832321737 0.5073334671069716 0.6119208600522092 1.0 0.934101285422588 14 P46934,P50570,Q96PU5,P05026,P62258 5 +Negative regulation of cysteine type endopeptidase activity 0.3312831457368438 0.5061988163214364 0.6127170858816418 1.0 0.934101285422588 19 P51812,Q15418,Q15392 3 +Regulation of amino acid transmembrane transport 0.6518184381167247 0.5060827519032676 0.6127985583186051 1.0 0.934101285422588 2 O75915 1 +L glutamate import across plasma membrane 0.6518184381167247 0.5060827519032676 0.6127985583186051 1.0 0.934101285422588 2 O75915 1 +Regulation of l glutamate import across plasma membrane 0.6518184381167247 0.5060827519032676 0.6127985583186051 1.0 0.934101285422588 2 O75915 1 +Lymphocyte mediated immunity 0.2945830931505179 0.5060240710936068 0.6128397516494553 1.0 0.934101285422588 35 P46108,P01889,P04439,P11279,Q9NUQ9,O96028,O15400,Q07021,Q96FV9 9 +Regulation of mitochondrial membrane potential 0.3192150474924236 0.5054223610203699 0.6132622165526052 1.0 0.93429538334119 22 P33897,Q9BSK2,P30536,Q9Y255,Q8IWA4,Q9UJZ1,Q9UII2 7 +C21 steroid hormone biosynthetic process 0.6473369206071069 0.5031652909472507 0.6148480655389206 1.0 0.9345633757914216 3 Q14849 1 +Regulation of protein complex stability 0.48419864559817 0.5027343341972925 0.6151510668466791 1.0 0.9347046247850416 5 Q7Z392,Q9BQ95,Q969V3,Q13501 4 +Positive regulation of carbohydrate metabolic process 0.4200190298012319 0.5017971964255818 0.6158101854393436 1.0 0.9353772724329243 7 O75746 1 +Regulation of proton transport 0.3938338061004873 0.5015527910314602 0.6159821344604137 1.0 0.9354224193826232 9 Q8TAD4,Q9NRA0,O43707,Q99623 4 +Neutrophil homeostasis 0.6466441060349752 0.5008947337149745 0.6164452090022037 1.0 0.9356935471053528 3 P04083,Q9BX67 2 +Regulation of microtubule nucleation 0.4196602037879949 0.5000913300532062 0.6170107706303098 1.0 0.9361199165941286 7 Q14203,Q9HD47 2 +Regulation of cytosolic calcium ion concentration 0.3079041462779596 0.4978876803129584 0.6185632111024852 1.0 0.9367620353688731 24 P06756,Q9Y3D6,P20020,P23634,P51572,O95202,P62942 7 +Meiosis i cell cycle process 0.3078781120464212 0.4976711145716075 0.6187158707073719 1.0 0.9367620353688731 24 Q92791,P46379,Q9BTX1,Q96KQ7,O94901,P53350 6 +Meiotic spindle organization 0.3929095857871965 0.4967716125506761 0.6193501157484587 1.0 0.9370458753250964 9 P30153 1 +Positive regulation of protein binding 0.3017071739898914 0.4965970485248498 0.6194732348963843 1.0 0.9370458753250964 26 Q07954,Q9BUN8,P05067,O75955,Q9Y2S7,Q15691,P62942 7 +Positive regulation of blood vessel endothelial cell migration 0.3796244944718341 0.496383861085297 0.6196236094245708 1.0 0.9370578246000004 11 P09601 1 +Response to salt stress 0.4514995162103701 0.4952172215233685 0.6204467954777 1.0 0.9371199309556012 6 O95202 1 +Estrogen metabolic process 0.4822571881102531 0.4949446989784661 0.6206391571693743 1.0 0.9371199309556012 5 Q53GQ0,O95470 2 +Organic hydroxy compound biosynthetic process 0.3110584106545683 0.4949382127379571 0.6206437358377741 1.0 0.9371199309556012 58 Q9H2C2,Q16850,P16435,O75845,Q15800,P04062,Q13510,Q14534,P04035,Q15125,Q14739,Q9NRA0,O15269,P00374,Q15392 15 +Glycerolipid metabolic process 0.3240529891145596 0.4948831406032137 0.6206826121150146 1.0 0.9371199309556012 78 Q9NZC3,Q9HBU6,Q9H490,Q9NPH0,Q92643,Q53H12,Q8NF37,O43292,Q8WTV0,Q16822,Q9NX62,Q99623,Q9NTJ5,Q92604,Q9HCL2,Q9BTU6,P50416,Q9UG56,Q9UJZ1,Q9NP80,Q96N66,O14735,Q8NCC3,Q10713,Q8TBX8,Q5H8A4,Q99758,Q8NCG7,Q9UBV2,Q9NUQ2 30 +Urogenital system development 0.2998839509263618 0.4945771885646419 0.6208986077133738 1.0 0.9371199309556012 47 O75844,O95470,Q9NZJ7,Q7LG56,Q02790,O76024,P07602 7 +Positive regulation of mitochondrial membrane potential 0.5176807367087399 0.4937293638929631 0.6214973245466013 1.0 0.9373051831100658 4 Q8IWA4 1 +Nucleoside triphosphate biosynthetic process 0.2884983756262178 0.4927353988502783 0.6221995619742735 1.0 0.9373924862939638 38 P56385,O75746,O75964,P00403,P00846,P06576,P24539 7 +Eye morphogenesis 0.3786695511636868 0.491156713331555 0.6233156119657575 1.0 0.9380502852955248 11 O95140,P54802,Q8NBN7,Q9P273,Q16706 5 +Negative regulation of endothelial cell proliferation 0.4809422873661801 0.4896873999192854 0.6243551193245147 1.0 0.9380502852955248 5 P57105 1 +Quinone metabolic process 0.3544817390108839 0.4883275773597841 0.6253178309628955 1.0 0.9380502852955248 13 Q8N0U8,Q96D53,O75208 3 +Neutrophil clearance 0.6464617987031371 0.4879755932944007 0.6255671288621882 1.0 0.9380502852955248 2 P04083 1 +Negative regulation of interferon gamma production 0.6464617987031172 0.4879755932943339 0.6255671288622355 1.0 0.9380502852955248 2 Q07021 1 +Mitochondrial fragmentation involved in apoptotic process 0.4492577215201998 0.4855303691734235 0.6273001756501717 1.0 0.9380976023763482 6 O00429,Q9Y3D6 2 +Relaxation of cardiac muscle 0.6417902004568448 0.4850832436658656 0.6276172976716292 1.0 0.9381452197241602 3 P05023 1 +Membrane invagination 0.3432856122118062 0.4841649222021524 0.6282688292575607 1.0 0.9387716480690071 14 Q08431,Q06481,O14964,P51790 4 +Myeloid leukocyte migration 0.2997968787729851 0.4837170716332121 0.6285866758402547 1.0 0.9387716480690071 27 Q08722,O00429,Q8N5M9,Q07021,P35613 5 +Neutrophil chemotaxis 0.3536735444874435 0.4834869061422258 0.6287500546972749 1.0 0.9387716480690071 13 P35613,O00429 2 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3901626738890213 0.4826219221662935 0.6293642106077473 1.0 0.9388918746096908 9 O76024,O60313 2 +Regulation of actin filament based movement 0.4154871595358345 0.4803517605376824 0.6309772895257861 1.0 0.9399632238303728 7 Q9HD47 1 +Pattern recognition receptor signaling pathway 0.2872523358156716 0.4799821981458521 0.631240051362961 1.0 0.9401417159905332 38 P51812,O43657,Q9NPR9,Q99623,Q5KU26,Q9NQC3,Q07021,Q06481 8 +I kappab kinase nf kappab signaling 0.3120680416607525 0.4786144364564297 0.6322129462321109 1.0 0.9404670589976062 61 O43657,Q5T9L3,Q96HY6,P09601,Q8TB61,Q99584,Q86UE4,P62942 8 +Axoneme assembly 0.6395939086294442 0.4779852050088506 0.6326607353602882 1.0 0.9407663704419208 3 Q15555,A0AVF1 2 +External encapsulating structure organization 0.2962479026048522 0.4771304530844265 0.6332692306452532 1.0 0.9409966809277376 31 P15291,Q53GQ0,Q92791,Q07954,Q96AY3,P05067,P13674,O75955 8 +Negative regulation of mrna catabolic process 0.2990385691945728 0.4734899958600043 0.6358636366746833 1.0 0.9409966809277376 26 P07910,O60506,P35637,Q92804,Q14011,Q9Y2W1,Q13151,P98175,Q06787,Q99729,Q14103 11 +Regulation of toll like receptor 3 signaling pathway 0.6381624312660941 0.4733781823307224 0.6359433926205531 1.0 0.9409966809277376 3 O75955 1 +Cohesin loading 0.511924239039648 0.4724258166447607 0.6366228806062895 1.0 0.9409966809277376 4 Q9Y6X3 1 +Cognition 0.2864743540453429 0.4720413637414378 0.6368972643508215 1.0 0.9409966809277376 38 Q92542,P17900,O00264,P04035,P50897,P05067 6 +Regulation of gliogenesis 0.3615488189746594 0.4718082605678868 0.6370636541613868 1.0 0.9409966809277376 12 P98164,P30536,P42345,Q96G23 4 +Protein localization to perinuclear region of cytoplasm 0.6370840523176629 0.4699177108698349 0.6384138102245387 1.0 0.9409966809277376 3 Q96ED9 1 +Ribonucleoside triphosphate metabolic process 0.2888332911818722 0.4690014853174147 0.6390685743346887 1.0 0.9409966809277376 40 P56385,O75746,O75964,P00403,O60313,P00846,Q8IWA4,P06576,P24539 9 +Phospholipid catabolic process 0.3376169721387675 0.4686010524028289 0.6393548249131302 1.0 0.9409966809277376 15 Q8NHP8,Q9NZC3,Q8WTV0,Q8NCC3 4 +Artery morphogenesis 0.4119812580255265 0.463913940420761 0.6427094047082058 1.0 0.9426647725352456 7 P98164,Q96AY3 2 +Response to zinc ion 0.4438118710045181 0.4621993969104955 0.6439383357039636 1.0 0.9426647725352456 6 Q8TAD4,P30536 2 +Cytokine production involved in immune response 0.3498809072202467 0.4609106202423096 0.6448627319413878 1.0 0.9426647725352456 13 P09601,P04439 2 +Post embryonic development 0.3328209703844803 0.4606444052762906 0.6450537474864004 1.0 0.9426647725352456 16 Q96A33,O95470 2 +Response to cold 0.3394790525162655 0.4604417784863195 0.6451991527100032 1.0 0.9426647725352456 14 P20020,Q06481,Q14011,P00403 4 +Synaptic vesicle priming 0.5085790949949724 0.4601767535342251 0.6453893554042338 1.0 0.9426647725352456 4 O95721 1 +Regulation of vasoconstriction 0.6339889573767294 0.4600347455030263 0.6454912810526172 1.0 0.9426647725352456 3 P42892 1 +Positive regulation of lipid metabolic process 0.3131093699831984 0.4578892722613365 0.6470319945000595 1.0 0.9433016946510476 22 P33897,P16435,Q92604,P50416,Q8WTV0,Q8NCG7,Q9NRA0,P42345 8 +Mitochondrial outer membrane permeabilization 0.3851635914609857 0.4569660764653723 0.6476954288624839 1.0 0.9434978594969116 10 P45880,P05141 2 +Tor signaling 0.2972155786765217 0.4554788429719789 0.6487647850636964 1.0 0.9446371466380188 25 O75844,Q9H4A6,P04062,Q96A49,P42345 5 +T cell activation 0.3106500730618101 0.4550826203742794 0.6490498008412526 1.0 0.9447843521657708 62 Q92542,Q08722,P24390,P30825,P04062,Q9HCL2,O96005,Q9Y255,P04439,Q9NUQ9,P62942 11 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.5070939872019438 0.4547703910086717 0.6492744337706866 1.0 0.9447843521657708 4 P30154 1 +Photoreceptor cell differentiation 0.4418599397093224 0.4539086921097274 0.6498945471416804 1.0 0.9451217834596832 6 P54802 1 +Ribonucleoside metabolic process 0.3843911244072828 0.4532005949391282 0.6504043040971956 1.0 0.9451217834596832 9 O60725,Q13126 2 +Cellular response to exogenous dsrna 0.4087202740080813 0.4487495726214619 0.6536123196263861 1.0 0.945344070689468 7 Q5KU26,O75955 2 +Post golgi vesicle mediated transport 0.29982914815849 0.4486245870696453 0.6537024941319931 1.0 0.945344070689468 51 Q9BZG1,P61026,Q8N1B4,Q9H4A6,P50570,O15027,Q8WVM8,Q01082,Q9UPN3,O14828,Q96A65,Q8N2H4,Q4J6C6,P98194,P61106,P42566,Q9Y4I1,Q96RL7,P11279,Q92538,O60826,O15127,Q96KP1 23 +Regulation of presynaptic cytosolic calcium ion concentration 0.6302483199506221 0.4481893441140413 0.6540165524301071 1.0 0.945344070689468 3 P23634 1 +Regulation of sequestering of triglyceride 0.6300056401579257 0.4474246506020684 0.6545684807541186 1.0 0.945344070689468 3 Q9BZF1,O60664 2 +Cardiac muscle cell contraction 0.3698822330095462 0.4436503008272355 0.6572954326758993 1.0 0.9457689214132388 11 Q96PU5,Q9HD47,P16615 3 +Response to sterol depletion 0.503915303345342 0.4432658275004693 0.6575734700462537 1.0 0.9457689214132388 4 Q15363 1 +Cellular response to sterol depletion 0.503915303345342 0.4432658275004693 0.6575734700462537 1.0 0.9457689214132388 4 Q15363 1 +Positive regulation of protein kinase b signaling 0.3262479648032411 0.4430921108495013 0.6576991112651513 1.0 0.9457689214132388 17 P07900,P98164,O95429,Q9NQC3,Q07021,Q86UE4 6 +Glycerophospholipid metabolic process 0.314478058636877 0.4422666006466418 0.6582962967388877 1.0 0.9457689214132388 69 Q9NZC3,Q9HBU6,Q9H490,Q9NPH0,Q92643,Q8NF37,O43292,Q8WTV0,Q9NX62,Q99623,Q9NTJ5,Q92604,Q9HCL2,Q9BTU6,Q9UG56,Q9UJZ1,Q9NP80,Q96N66,Q10713,Q8NCC3,O14735,Q8TBX8,Q5H8A4,Q99758,Q9NUQ2 25 +Fibroblast proliferation 0.3364585209186641 0.4418010384555643 0.6586331870461621 1.0 0.9457689214132388 14 O75844 1 +Activation induced cell death of t cells 0.5034474040906053 0.4415801972661292 0.6587930164768081 1.0 0.9457689214132388 4 Q9HCL2 1 +Regulation of platelet derived growth factor receptor beta signaling pathway 0.6323653791936787 0.4415338736118964 0.6588265442806724 1.0 0.9457689214132388 2 Q07954 1 +Regulation of receptor internalization 0.3461446622173511 0.4389051195754802 0.6607302869910903 1.0 0.9473298592321538 13 Q8IZ07,O75955,O00560,Q06787 4 +Negative regulation of immune response 0.293752383461429 0.4352480581283516 0.6633823827130545 1.0 0.9489725688017012 28 P46108,P09601,Q7Z739,P28070,P01889,P04439,Q86UT6,Q96FV9 8 +Positive regulation of sequestering of triglyceride 0.6298280236819921 0.4333693871978694 0.6647464366061493 1.0 0.9489725688017012 2 O60664 1 +Ventral spinal cord development 0.6252027340625494 0.4323874921351487 0.6654598072944964 1.0 0.9489725688017012 3 Q14203 1 +Brain morphogenesis 0.4364168572801573 0.4309988369072505 0.6664692161871626 1.0 0.9489725688017012 6 P04062 1 +Cellular response to gamma radiation 0.3541131691820856 0.4298805722746334 0.6672825183973874 1.0 0.9489725688017012 12 O75844 1 +Intraciliary retrograde transport 0.6287003101212372 0.429760535474629 0.6673698431672321 1.0 0.9489725688017012 2 Q7Z4L5 1 +Positive regulation of double strand break repair via homologous recombination 0.3280045879221394 0.4293669232779408 0.6676562210753101 1.0 0.9489725688017012 16 Q7Z4V5,P35637 2 +Necroptotic signaling pathway 0.6281364533408433 0.4279607198361049 0.6686797186152516 1.0 0.9489725688017012 2 P49327 1 +Regulation of protein localization to cell surface 0.3664659874352734 0.4254885439498011 0.6704805711295294 1.0 0.9489725688017012 11 Q96PU5,Q9HD47,Q12846 3 +Negative regulation of interleukin 2 production 0.627290668170293 0.4252667883223436 0.6706422014192006 1.0 0.9489725688017012 2 P14373 1 +Regulation of organic acid transport 0.3787629095358237 0.4244180198794345 0.6712609812330537 1.0 0.9489725688017012 10 Q7L0J3,Q9Y3D6,O75915,P31751,P55011 5 +Negative regulation of axonogenesis 0.4347410725948778 0.4240095121362403 0.6715588761662965 1.0 0.9489725688017012 6 Q8N0X7,Q9NQC3 2 +Regulation of dna ligation 0.6223914269599559 0.423672841973237 0.6718044239773713 1.0 0.9489725688017012 3 Q9UBB9,P09429 2 +Negative regulation of calcineurin mediated signaling 0.4982564854671208 0.4230177993481369 0.672282274663905 1.0 0.9489725688017012 4 P23634 1 +Negative regulation of calcium mediated signaling 0.4982564854671208 0.4230177993481369 0.672282274663905 1.0 0.9489725688017012 4 P23634 1 +Response to nitric oxide 0.3825113046039343 0.4206000702338373 0.6740471424440633 1.0 0.9489725688017012 8 P46108,Q14103,P50570 3 +Cellular response to reactive nitrogen species 0.3825113046039343 0.4206000702338373 0.6740471424440633 1.0 0.9489725688017012 8 P46108,Q14103,P50570 3 +Cell maturation 0.2920050005051439 0.4200418461172343 0.6744548843159031 1.0 0.9489725688017012 28 P30153,P04062,Q9NZJ7,Q8N2A8,Q9Y2W6,P05067,O75503,Q12768 8 +Regulation of platelet derived growth factor receptor signaling pathway 0.496856659636238 0.4180563383526628 0.6759059266123069 1.0 0.9489725688017012 4 Q07954 1 +Protein retention in golgi apparatus 0.6205341978808508 0.4179516932169582 0.6759824364962703 1.0 0.9489725688017012 3 Q96RL7 1 +Positive regulation of growth 0.295747562635643 0.417750191871729 0.6761297709205958 1.0 0.948976846637806 50 P51812,O75312,Q9GZP9,Q9BSK2,Q96PU5,Q9HCL2,O95684,Q15418,O76024 9 +Cellular response to retinoic acid 0.3769279785939659 0.4158215774649811 0.6775405683588784 1.0 0.949950507383212 9 Q9P0J0 1 +Negative regulation of rig i signaling pathway 0.496060620030078 0.415243448869121 0.6779636949183216 1.0 0.949950507383212 4 Q07021 1 +Regulation of ion transmembrane transport 0.3075347508371278 0.4140533739502053 0.6788350185639 1.0 0.9501378840380444 63 O75844,P46934,O43707,Q99623,Q13586,Q96PU5,Q9HD47,P27105,Q06787,P21796,P05067,P23634,Q9NRA0,Q8TAD4,P62942 15 +Golgi to plasma membrane protein transport 0.3201466175228259 0.4126273426415681 0.679879665249683 1.0 0.9507906779390104 18 Q9BZG1,Q9UPN3,P61026,Q9H4A6,O15027,Q01082,Q8N2H4,Q4J6C6 8 +Regulation of protein localization 0.2408769130932128 0.4104481377582645 0.6814772403303717 1.0 0.9513230363446898 242 Q15154,Q10713,Q9H4A6,O00264,Q05D32,Q32P28,P53985,Q8WVM8,P02545,Q01082,O15258,Q9NQC3,P23634,P51572,P55011,P60604,Q5T9L3,P07900,Q7Z3B4,Q7Z5K2,Q07954,O60499,P12270,Q9HD47,P27105,O95429,O15400,Q9C0E2,P78371,P62942,P53350,P02786,Q16822,Q9Y371,O75312,Q8IZ07,Q16836,P50402,Q8N183,Q96PU5,Q9GZY8,P49755,P04035,Q8N5M9,Q9NR31,P50416,Q14012,O94874,Q9H300,P49257,Q9UII2,Q16850,O14737,Q9GZP9,Q12846,Q96HY6,Q9Y282,O43752,Q13438,Q92544,O95563,Q96JH7,Q9Y3D6,O00429,Q96KC8,Q9NV96,O96028,P62258 68 +Positive regulation of dna ligation 0.6222159571468909 0.4092510299168078 0.6823554488432217 1.0 0.9518331272389404 2 P09429 1 +Cilium movement 0.3997112487252978 0.4075227328335438 0.6836241011991531 1.0 0.9519826448263288 7 Q96RL7 1 +Retinol metabolic process 0.3995896127893503 0.4069731362386233 0.6840277187374131 1.0 0.9519826448263288 7 Q6UX07,Q9Y394,Q8NBN7 3 +Positive regulation of anion transmembrane transport 0.6164367273204711 0.4054326734010271 0.6851594981323785 1.0 0.9519826448263288 3 P08183 1 +Modulation by host of viral genome replication 0.3740072135790729 0.4014117837617665 0.6881169750659253 1.0 0.9519826448263288 9 P27105 1 +Anaphase promoting complex dependent catabolic process 0.3486862828309485 0.3998677370925218 0.689253936315031 1.0 0.9519826448263288 12 Q16763,Q9UJX5,Q9UJX4,Q9H1A4,Q13042,P53350 6 +Transcytosis 0.3731694042937527 0.3973021770593138 0.6911446421632033 1.0 0.9519826448263288 9 P98164,Q07954,P55899 3 +Regulation of adherens junction organization 0.613530087893916 0.3966396166716391 0.6916332339702109 1.0 0.952244458828151 3 P35611 1 +Positive regulation of monocyte chemotaxis 0.6131899453187867 0.3956154524844643 0.6923887358202474 1.0 0.9530851225386704 3 Q99538 1 +Positive regulation of amino acid transport 0.6119571347997833 0.3919120207510493 0.6951232207965479 1.0 0.9558035228848936 3 P05556,P55011 2 +Taurine transport 0.6162954609529248 0.3908936547025751 0.6958758443913018 1.0 0.9558035228848936 2 Q8TDW0 1 +Positive regulation of protein catabolic process in the vacuole 0.6113519633954624 0.3900989726082025 0.6964633625141556 1.0 0.9560925767596749 3 P98164 1 +Negative regulation of blood circulation 0.6104313397136227 0.387347100394574 0.6984992606479907 1.0 0.95624763072194 3 P16615 1 +Cellular response to estrogen stimulus 0.48744710860366 0.3852143988381631 0.7000785762497606 1.0 0.9562480933913828 4 Q9H7N4,Q9H6U6,Q969T9 3 +Potassium ion import across plasma membrane 0.4251090604575721 0.3844553978568328 0.7006409477971105 1.0 0.9562480933913828 6 P54709,P05026,P05023,P55011 4 +Response to testosterone 0.3457584285326954 0.3838970374070966 0.7010547622426975 1.0 0.9562480933913828 12 P30536,P04062,P49321 3 +Leukotriene biosynthetic process 0.4866797245155768 0.3825762566047502 0.7020339777801934 1.0 0.9562480933913828 4 Q9UJ14 1 +Calcium ion transport into cytosol 0.3237849173020286 0.3821119539447419 0.7023783254297915 1.0 0.9562480933913828 15 O95202,P62942 2 +Response to progesterone 0.452864910662129 0.3813653919725586 0.7029321373034392 1.0 0.956549032042653 5 P30536 1 +T cell differentiation involved in immune response 0.4523824346957175 0.3795760839014352 0.704260116697919 1.0 0.9570080139508704 5 P42345,Q04656 2 +Cellular response to mineralocorticoid stimulus 0.6074361642803744 0.3784467205702088 0.7050987664072617 1.0 0.9570571170655846 3 P20020 1 +Inositol lipid mediated signaling 0.3199836955082124 0.3783592325882302 0.705163748756046 1.0 0.9570571170655846 16 P46934,Q10713 2 +Ventricular septum development 0.3567508882513531 0.374877171638384 0.7077518174620219 1.0 0.957785095914249 11 O96028,Q15643 2 +Regulation of dna helicase activity 0.6061640779373165 0.3746912171945705 0.7078901248653131 1.0 0.957785095914249 3 Q04837 1 +Inositol phosphate metabolic process 0.3680822240133614 0.3725844604349769 0.709457740177398 1.0 0.9591018964146883 9 Q9BW91,Q9NX62 2 +Positive regulation of intracellular lipid transport 0.6100930363687721 0.3720528651409528 0.7098534893144448 1.0 0.9591018964146883 2 P22307 1 +Positive regulation of leukocyte cell cell adhesion 0.2867736782646269 0.3719319489701553 0.7099435169759845 1.0 0.9591018964146883 27 Q08722,P30825,Q9HCL2,Q9NUQ9 4 +Regulation of plasma membrane organization 0.4834728455446569 0.3716194296397568 0.7101762207728648 1.0 0.9591018964146883 4 Q9Y371 1 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.3718044835097019 0.3695559871778927 0.7117133500261761 1.0 0.9591018964146883 8 Q99442,O43681,P46379 3 +Regulation of tor signaling 0.3116834241526457 0.3686999004305361 0.7123514229726071 1.0 0.9591018964146883 19 O75844 1 +Head morphogenesis 0.421117619656647 0.3683893043270273 0.7125829714940664 1.0 0.9591018964146883 6 O95470 1 +Positive regulation of mammary gland epithelial cell proliferation 0.6036854866763463 0.3674164737372795 0.7133083853306972 1.0 0.9591018964146883 3 Q9NQC3 1 +Spinal cord development 0.3335961972584856 0.3668859699895693 0.713704077140376 1.0 0.9591018964146883 13 P07196,Q14203,O75312 3 +Regulation of defense response to virus 0.3112550285080262 0.3657958912264773 0.71451738604844 1.0 0.9591018964146883 19 O43657 1 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.354864548043443 0.3652397466090031 0.7149324511428858 1.0 0.9591018964146883 11 P45880,P05141 2 +Regulation of morphogenesis of an epithelium 0.6029328821206935 0.365218805588727 0.7149480816152143 1.0 0.9591018964146883 3 Q9Y5V3,Q99623 2 +Cilium or flagellum dependent cell motility 0.4198539033571309 0.3633442587991095 0.7163477354161893 1.0 0.959476715143104 6 Q96RL7 1 +Regulation of leukocyte apoptotic process 0.3538523951734562 0.3600953499658246 0.7187758300610265 1.0 0.9600047218982742 11 Q9HCL2 1 +Negative regulation of protein targeting to mitochondrion 0.5997337381955137 0.3559362102791812 0.7218883373896126 1.0 0.9600047218982742 3 P49257 1 +T cell differentiation 0.2837182560792434 0.3530210474026338 0.7240726615722994 1.0 0.9600047218982742 29 P24390,P04062,O96005 3 +Phospholipid metabolic process 0.314206606693087 0.3530110241386425 0.7240801758678286 1.0 0.9600047218982742 87 Q9NZC3,Q9HBU6,Q9H490,P37268,Q9NPH0,Q92643,Q8NF37,O43292,Q8WTV0,Q86YN1,Q9NX62,Q99623,Q9NTJ5,Q92604,Q9HCL2,Q9BTU6,Q9UG56,Q9UJZ1,Q9NP80,Q96N66,O14735,Q8NCC3,Q10713,Q8TBX8,Q5H8A4,O15269,Q8NHP8,Q99758,Q9NRA0,Q9NUQ2 30 +Regulation of dendrite morphogenesis 0.3108076706777644 0.3506006129569025 0.725887996620852 1.0 0.9614557043995964 18 P46934 1 +Positive regulation of morphogenesis of an epithelium 0.6027628982238592 0.3503199447802685 0.7260985987156447 1.0 0.9614557043995964 2 Q9Y5V3 1 +Positive regulation of neurotransmitter uptake 0.6024809698336726 0.3494958759827228 0.7267170663543505 1.0 0.96188733053181 2 P05556 1 +Interleukin 6 production 0.311689591286845 0.3482585463564514 0.727646022699346 1.0 0.962491862156367 17 Q08722,P04062,Q9NRA0,Q86UT6,P05067 5 +Regulation of systemic arterial blood pressure by hormone 0.5969584792454085 0.3479620975765686 0.7278686485806716 1.0 0.962491862156367 3 P42892 1 +Pigment accumulation 0.4755349057777768 0.3449833057298705 0.7301069212827613 1.0 0.9632971082330232 4 Q9BXS5 1 +Pigment granule maturation 0.4755349057777768 0.3449833057298705 0.7301069212827613 1.0 0.9632971082330232 4 Q9BXS5 1 +Negative regulation of rna splicing 0.3145021241208123 0.3443542821838806 0.7305798662503213 1.0 0.9633658040862224 16 P61978,P26368,P98175,Q07021,P38159,P22626 6 +Cytokine production involved in inflammatory response 0.3619937312024104 0.3435593431531177 0.7311777048997286 1.0 0.9635254989231646 9 P33897,Q8IV08 2 +Response to misfolded protein 0.3656035622128087 0.3408152706621681 0.7332426536778887 1.0 0.9636265185926036 8 Q9BUN8 1 +Positive regulation of rna splicing 0.2882749160889548 0.3396616684876172 0.7341113313530294 1.0 0.9636265185926036 24 O75312,P62995,P26368,Q14011,P38159,P98179,Q96QD8 7 +Golgi to plasma membrane transport 0.2828333290621458 0.339155557859135 0.7344925468458987 1.0 0.9636265185926036 27 Q9BZG1,Q9UPN3,P61026,Q9H4A6,P50570,O15027,Q01082,O60826,Q96A65,Q8N2H4,Q96KP1,Q4J6C6 12 +Positive regulation of cell cycle checkpoint 0.4137171269409966 0.3391393211362093 0.7345047778454836 1.0 0.9636265185926036 6 Q9Y6D9,P12270 2 +Receptor localization to synapse 0.3613110948273521 0.3388706618900202 0.7347071665820262 1.0 0.9636265185926036 10 P57105,Q14168,O15400 3 +Zymogen activation 0.3609488174440575 0.3386419889018986 0.7348794470376669 1.0 0.9636265185926036 9 Q15392 1 +Endocytosis 0.2988959631998116 0.337084369091059 0.7360533002573453 1.0 0.9637711638050088 134 Q96D71,Q9BZG1,P06756,Q08380,Q5KU26,P50897,P05067,Q08431,O15260,P46934,P98164,P62820,Q07954,P22413,Q8WTV0,Q06787,O15118,O75955,P02786,Q8IZ07,Q9NX40,Q9Y2T2,P57105,Q5VW38,Q96PU5,P11717,P61020,Q7Z6M1,Q5JRA6,O00429,O00560,P27824,P51790,Q14108,Q96ED9,Q06481 36 +Positive regulation of cell activation 0.2830476985773896 0.3360246881626255 0.7368522493751395 1.0 0.96426695476632 46 Q08722,P12956,P30825,Q9HCL2,P04439,P11279,Q9NUQ9,O96028,Q15418 9 +Tissue remodeling 0.3085588895458734 0.3359987850275577 0.7368717826753115 1.0 0.96426695476632 18 O14773 1 +Positive regulation of protein localization to cell periphery 0.2923001292878429 0.3343955071743352 0.7380811292354308 1.0 0.965273332070278 23 Q12846,O00264,Q07954,O15258,Q9HD47,P23634 6 +Phospholipid dephosphorylation 0.4716039984874556 0.3320580173023628 0.7398454504876311 1.0 0.9664045211729247 4 Q10713 1 +Notch signaling pathway 0.2963229196575309 0.3320276058850304 0.7398684138623 1.0 0.9664045211729247 22 P05067,P57105,Q9UBV2 3 +Appendage morphogenesis 0.3271428898692744 0.3311086976933303 0.7405623820452396 1.0 0.9664045211729247 13 Q9NX62 1 +Positive regulation of chemotaxis 0.3145563701113507 0.326743332310642 0.7438620230322353 1.0 0.967638553299646 15 Q07021,O00429,Q99538 3 +Regulation of toll like receptor signaling pathway 0.3347542797168535 0.3253830906915599 0.7448911515188466 1.0 0.9685941288136524 12 Q06481,Q9NPR9,Q9NQC3 3 +Cerebellar cortex morphogenesis 0.3576522880905073 0.3215961118667104 0.7477586897675768 1.0 0.969447842026681 10 O15020,P04062,Q15058,Q96D53 4 +Adherens junction assembly 0.4359480812640929 0.3202787863383011 0.748757002917698 1.0 0.9697862954292438 5 P35222,P18206,Q13177,Q9BX67 4 +Lactation 0.3328485847179373 0.3155085498641991 0.7523755604760438 1.0 0.9712823241930728 12 Q9UNS2,Q13505,P00403 3 +Regulation of tolerance induction 0.5852877389821498 0.315252062840397 0.7525702788639044 1.0 0.9712823241930728 3 P01889 1 +Tolerance induction 0.5852877389821498 0.315252062840397 0.7525702788639044 1.0 0.9712823241930728 3 P01889 1 +Phosphorylation of rna polymerase ii c terminal domain 0.4339729119638763 0.313378999507362 0.7539927372401793 1.0 0.9715534196891624 5 Q8WUA2,Q9NYV4,P32780,O60885 4 +Transport along microtubule 0.2924636270765727 0.31326261889062 0.7540811476464495 1.0 0.9715534196891624 57 Q8WXH0,Q15154,P07196,O95295,O75381,Q5SNT2,Q8TD16,Q9Y2T2,Q9Y366,Q9UBK9,P62820,P23246,O60313,P78537,P11279,Q14203,P05067 17 +Microtubule based transport 0.2924636270765727 0.31326261889062 0.7540811476464495 1.0 0.9715534196891624 57 Q8WXH0,Q15154,P07196,O95295,O75381,Q5SNT2,Q8TD16,Q9Y2T2,Q9Y366,Q9UBK9,P62820,P23246,O60313,P78537,P11279,Q14203,P05067 17 +Receptor mediated endocytosis 0.3000258178174757 0.3130514287596559 0.7542415898551367 1.0 0.9715534196891624 66 Q96D71,P02786,Q8IZ07,P06756,P46934,Q5VW38,P98164,O00560,Q07954,P27824,P50897,Q7Z6M1,Q14108,Q06787,P05067,O75955 16 +Negative regulation of mrna metabolic process 0.2794871203462257 0.3129460311242867 0.7543216649392153 1.0 0.9715534196891624 45 P61978,P07910,O60506,P35637,Q92804,Q14011,P26368,P98175,Q06787,Q99729,Q07021,P38159,O75150 13 +Srp dependent cotranslational protein targeting to membrane 0.3439945063790873 0.3110189399646024 0.7557862231975903 1.0 0.9723798884918918 11 Q9UHB9,Q15629 2 +Phagosome lysosome fusion 0.5829232004342124 0.308791498250028 0.7574801367305155 1.0 0.9737972750736124 3 Q9BZG1 1 +Hormone catabolic process 0.5827345748025352 0.3082785943302922 0.7578703526543249 1.0 0.9740555046479242 3 P42892 1 +Positive regulation of apoptotic signaling pathway 0.2777494823303186 0.3067357786034392 0.759044494296921 1.0 0.9744750417706128 30 P30153,Q9Y3D6,P49327,O00429,P23246,P30154,Q9NQX7,Q07820,P51572 9 +Response to leucine 0.5814385425018764 0.3047644087672301 0.7605455904202185 1.0 0.975089517935074 3 P42345 1 +Cellular response to leucine 0.5814385425018764 0.3047644087672301 0.7605455904202185 1.0 0.975089517935074 3 P42345 1 +Negative regulation of cell death 0.233076914430577 0.3035430424307584 0.7614760506230733 1.0 0.9753897392350708 230 P06756,Q9H4A6,P09601,Q7LG56,P02545,Q9Y255,P50897,O76024,Q96TA2,Q9UEE9,Q15392,Q4ZIN3,O95881,Q9NVI7,P07196,Q9HD42,Q01105,P98164,P04062,P49327,Q15058,P46379,Q86TM6,Q86UE4,O15118,Q15418,P05141,Q99538,P53350,P51812,P02786,Q9H3K2,O75312,Q99623,Q9HCL2,Q12981,O60313,P61289,P21796,Q9H300,Q07820,P12235,P16435,P45880,Q96HY6,Q86XL3,Q8N2F6,Q9P0J0,Q13217,Q9NQ88 50 +Regulation of production of molecular mediator of immune response 0.2780606888710785 0.3022502991825482 0.7624612629477294 1.0 0.9761938342237136 28 Q12846,Q99623,P09601,P04439,Q9NRA0,O96028,Q96FV9 7 +Macrophage differentiation 0.3534052566318842 0.3018591964171706 0.76275940213795 1.0 0.9761954831409412 10 P04062 1 +Establishment of protein localization to plasma membrane 0.2782386872599027 0.3003287258862299 0.763926423894846 1.0 0.9765283994186824 25 Q9BZG1,Q9UPN3,P61026,Q9H4A6,O15027,P51149,Q01082,Q15904,Q9H8Y8,Q8N2H4,Q4J6C6 11 +Regulation of lipid biosynthetic process 0.2768855785792229 0.2994427484447812 0.7646022490383138 1.0 0.9767743250691132 30 P33897,P16435,Q92604,P30536,Q8NF37,Q13510,Q99758,Q8WTV0,Q9NRA0,P42345 10 +Establishment of endothelial intestinal barrier 0.3524089444298649 0.2991967063589742 0.7647899622066208 1.0 0.9767743250691132 9 P62820,P49327,Q9H0U4,Q07157 4 +Lipid droplet organization 0.352448472963638 0.2974609470241009 0.7661146190810637 1.0 0.9775255484223077 10 Q8N0X7,Q96CS3,Q14534 3 +Embryonic appendage morphogenesis 0.3411825299621188 0.2973796123331838 0.7661767070270633 1.0 0.9775255484223077 11 Q9NX62 1 +Positive regulation of ubiquitin protein transferase activity 0.3286591504458215 0.294087953267334 0.7686906959732178 1.0 0.978773859483648 12 Q9BTE7,Q92564 2 +Memory 0.3515384078013464 0.2932942276845651 0.7692972653938694 1.0 0.9792274268425546 10 O00264,Q99538 2 +Positive regulation of viral life cycle 0.3506310633654791 0.2911580036102821 0.7709304800289405 1.0 0.980926633226996 9 P07237,P52292 2 +Signal release 0.2861836002875552 0.2904751075926212 0.771452791500894 1.0 0.9814013558416594 53 P53985,P50897,P04083,O95721,O15439,Q5T9L3,P62820,Q06787,O95295,Q16822,Q7L0J3,Q16836,P16615,Q8N183,Q8N5M9,P50416,Q12846,O95563,Q96TA1 19 +Regulation of ossification 0.3194600391205409 0.2897673609056264 0.7719942192909772 1.0 0.9816895785610747 13 O75844,Q8N5W9,P20020 3 +Cholesterol efflux 0.3506500393636513 0.2892427610903668 0.7723956109923562 1.0 0.9816895785610747 10 P61916,Q07954,Q99758,Q8WTV0,O15118,Q86Y82 6 +Pointed end actin filament capping 0.5799266986185496 0.2865412958018245 0.7744635692751638 1.0 0.982381271961958 2 Q9NYL9 1 +Regulation of stress granule assembly 0.5742796905088199 0.2856698840152716 0.7751309729373894 1.0 0.982697576051143 3 Q9UN86 1 +Pore complex assembly 0.3269042813258698 0.2852362142295943 0.7754631772903524 1.0 0.982697576051143 12 Q9BTX1,Q9NQC3 2 +Positive regulation of leukocyte proliferation 0.3015009733046311 0.2850982325018746 0.7755688841451849 1.0 0.982697576051143 17 P02786,P30825,P04439,Q9HCL2 4 +Response to molecule of bacterial origin 0.2726283046916602 0.2829580408248887 0.7772090016267978 1.0 0.982697576051143 42 P51812,Q86UE4,Q8WTV0,Q9NUQ9 4 +Negative regulation of fibroblast apoptotic process 0.5731521411804963 0.2827119823123392 0.7773976302615617 1.0 0.982697576051143 3 Q9UEE9 1 +Response to ether 0.4560292078378347 0.2826800343919896 0.7774221225232616 1.0 0.982697576051143 4 Q9H4A6,Q14103 2 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.3484994557252839 0.2816019590552226 0.7782487378687373 1.0 0.982697576051143 9 P07602 1 +Regulation of epithelial cell migration 0.2785020621667622 0.2803767166481863 0.7791884983846016 1.0 0.9830871258978306 47 P57105,P09601,Q8WTV0,Q9NQC3,P23634,P06576,P42785 7 +Mammary gland epithelial cell proliferation 0.3978001591705947 0.2787959443826601 0.7804014270217681 1.0 0.9839244619258396 6 Q99623,Q9NQC3 2 +Regulation of apoptotic signaling pathway 0.3086115159281544 0.2745691648573998 0.7836472589949008 1.0 0.9860432413257056 99 P06756,P09601,Q7LG56,P02545,Q9Y255,O76024,P51572,O95881,P07237,P30154,Q86TM6,Q9NQX7,P05141,Q9H3K2,P30153,P23246,O60313,P61289,Q9H300,Q07820,P45880,Q12846,Q9Y3D6,Q8N2F6,O00429,Q9P0J0 26 +Hyperosmotic response 0.3683751305549197 0.2730960796585767 0.7847793602088073 1.0 0.9863355345104768 7 Q9BPX6,O95202 2 +Cardiac chamber morphogenesis 0.3161017246018381 0.272155151547805 0.7855027245247892 1.0 0.986654997707984 13 P09493,O96028,P62942 3 +Oocyte maturation 0.4212346371894913 0.2701427403964573 0.7870504419188213 1.0 0.98745006113694 5 P30153 1 +Granulocyte migration 0.2943804336152039 0.2680980170711874 0.7886238721296588 1.0 0.9875817225812578 20 Q8N5M9,P35613,O00429 3 +Cyclic gmp amp transmembrane import across plasma membrane 0.5662718556119648 0.2649614103391835 0.7910391897044142 1.0 0.9890101962121552 3 Q8IWT6,Q8TDW0 2 +Gdp metabolic process 0.4498384360274698 0.2639101233491692 0.7918491748141832 1.0 0.9895481707681708 4 Q9UDY2,Q14168 2 +Adaptive thermogenesis 0.2725640092563113 0.2634243393288437 0.7922235328132261 1.0 0.9897435611027592 30 P23786,P12235,Q16836,Q96E52,Q9UIQ6,P05141 6 +Regulation of gene silencing by rna 0.2966286571178669 0.260974071748174 0.7941125023049427 1.0 0.9907857794657426 18 O75844,P51114 2 +Specification of symmetry 0.3652118984375108 0.2604196381282299 0.7945400963695757 1.0 0.9907857794657426 7 Q15363 1 +Transcription coupled nucleotide excision repair 0.4485190409026667 0.2599756808892085 0.794882532608955 1.0 0.9907857794657426 4 P19447,P18074,Q9HCS7 3 +Non lytic viral release 0.347190043467148 0.2594995493533215 0.7952498296791326 1.0 0.9907857794657426 8 Q9HD42,Q9Y3E7,Q8WUX9 3 +Negative regulation of establishment of protein localization 0.2725650469308272 0.2564810506977943 0.7975794105540204 1.0 0.9927004926637142 27 P60604,Q16850,Q16836,Q9GZP9,Q13438,P04035,Q8N5M9,O95429,P49257 9 +Adaptive immune response 0.2721986450178866 0.2549127779701772 0.7987904668319985 1.0 0.993638152194319 44 P02786,P01889,P10321,Q03518,P04083,P04439,Q9NZ08,Q9NUQ9,O15400,Q07021,O96028,Q96FV9,P42345 13 +Platelet derived growth factor receptor beta signaling pathway 0.5620495697730008 0.2543263302411442 0.7992434598061897 1.0 0.993638152194319 3 Q07954 1 +Actin filament based transport 0.3420578747286658 0.2532861631513292 0.8000470877794466 1.0 0.993638152194319 9 Q9UH99,O43707 2 +Regulation of ion transport 0.3039759625550796 0.2527071586289773 0.8004945156167269 1.0 0.993638152194319 84 O43707,P50570,O76024,P05067,Q8TAD4,P23634,P05023,P55011,P46934,P20020,Q9HD47,P27105,Q06787,P62942,Q7L0J3,Q99623,Q96PU5,P21796,O75844,Q04656,Q13586,P30536,Q9NRA0,P08183,P62258 25 +Negative regulation of epithelial cell proliferation 0.301563074649724 0.2525413843933861 0.8006226303186115 1.0 0.993638152194319 15 Q9UII2,P57105,Q99623 3 +Citrulline biosynthetic process 0.4458484656865733 0.2520841236680387 0.8009760412598981 1.0 0.993638152194319 4 P23634 1 +Leukocyte apoptotic process 0.2919075309039927 0.2520479250854052 0.8010040204205677 1.0 0.993638152194319 20 P24390,Q9HCL2 2 +Negative regulation of transport 0.3040327277070377 0.2497485332025905 0.8027818231310093 1.0 0.993638152194319 85 P06756,P09601,P05067,P46934,P22413,Q06787,P62942,Q8IZ07,Q16836,Q96PU5,P04035,Q8N5M9,P21796,Q08722,Q16850,Q9GZP9,Q9Y3D6,Q13438,O00560,Q06481 20 +Negative regulation of ossification 0.4448613307425551 0.2491917824692219 0.8032124356159447 1.0 0.993638152194319 4 Q8N5W9 1 +C21 steroid hormone metabolic process 0.4445397835737567 0.2482525293074896 0.8039390255804679 1.0 0.993638152194319 4 Q14849 1 +Lipid droplet formation 0.4444293182076988 0.2479301839268145 0.8041884254634826 1.0 0.993638152194319 4 Q14534 1 +Lymphocyte migration 0.330431975821065 0.2468349940745562 0.8050359269015148 1.0 0.993638152194319 11 P05067,P46108,P04062,Q5JRA6 4 +Long chain fatty acid biosynthetic process 0.4440231911463891 0.246746524980268 0.8051043978182222 1.0 0.993638152194319 4 Q96PU8 1 +Response to ischemia 0.3303585589900345 0.2464989462584527 0.8052960200435657 1.0 0.993638152194319 11 P52789,Q15018,Q96RD7 3 +Membrane fission 0.5582387689734468 0.2448993758719629 0.8065343449606608 1.0 0.993638152194319 3 Q9Y371 1 +Regulation of mitotic spindle assembly 0.3106656416924949 0.244276062933604 0.8070170210264118 1.0 0.993638152194319 13 Q9HD42,Q8WUX9,P12270,Q9Y3E7,P53350 5 +Microtubule anchoring at centrosome 0.4131757368544086 0.2439768690268755 0.8072487345180919 1.0 0.993638152194319 5 Q15154,Q14203 2 +Atp metabolic process 0.3006956423358422 0.2403221884210082 0.8100804950949185 1.0 0.9952105820053128 120 Q9UDW1,P54619,P33897,P52789,O14949,P00846,O43676,P05067,O95139,P56385,O14548,P15954,O75964,P00403,P22413,P06576,Q9H3K2,O75746,O75208,P03886,P13073,Q9Y6M9,Q9UJZ1,P14406,Q9UII2,P51970,O96000,Q9BSK2,Q04656,Q9Y3D6,P30536,O00429,Q9BRR6,Q9NRA0,Q7KZN9,Q9NQ88,P24539 37 +Cardiac muscle cell membrane repolarization 0.3595974070816701 0.2383731607701894 0.811591682119627 1.0 0.9962371208101506 7 O75844,P05023,P62258 3 +Leukotriene metabolic process 0.3860902205601463 0.2368619491111366 0.812763890247191 1.0 0.9968803704698144 6 P33527 1 +Forebrain cell migration 0.3282097817104594 0.2367205860486359 0.8128735634528834 1.0 0.9968803704698144 11 Q8WXH0,Q96N66,Q9NQC3 3 +Regulation of hydrolase activity 0.2184478014901364 0.2348062746188467 0.8143590974429573 1.0 0.9976706201983088 187 Q9NZJ7,Q9Y255,P50897,Q15363,P04083,P05067,P51572,Q15392,Q14155,Q96A26,P49327,Q07954,Q15043,Q9UL46,O95819,Q15418,P07602,Q15375,Q8N5V2,P62942,Q99538,P51812,O15031,Q99623,P49755,Q9P2J5,P61289,Q9UII2,P42345,Q92542,P46108,Q9NR28,O14737,P16435,Q96HY6,Q9Y3D6,Q9P0J0,P40616,P78318,Q14108,Q9NRA0,Q86VI3,Q06481 43 +Regulation of cellular response to growth factor stimulus 0.2683261116435907 0.2304448580343909 0.8177461072857861 1.0 0.9990890063193322 43 Q92896,P46934,Q05D32,P98164,O00560,O14964,P23634,Q92859,Q8N0X7,P62942 10 +Relaxation of muscle 0.4379970979248016 0.229453689919287 0.8185163105319757 1.0 0.9990890063193322 4 P05023 1 +Positive regulation of adaptive immune response 0.2918483762367327 0.2281282329761038 0.8195465519783556 1.0 0.9990890063193322 17 P01889,P04439,Q9NUQ9,O15400,O96028 5 +Negative regulation of bone mineralization 0.5512558905958667 0.2280555890311872 0.8196030251522914 1.0 0.9990890063193322 3 Q8N5W9 1 +Positive regulation of amyloid beta clearance 0.5508323501259624 0.2270520633759561 0.8203832584458874 1.0 0.9995666340864396 3 Q07954 1 +Copii coated vesicle budding 0.2811958396140681 0.2262381711436062 0.8210161838569208 1.0 1.0 22 Q9NR31,Q15363,P49755,Q5JRA6 4 +Phosphatidylinositol dephosphorylation 0.5502248311086163 0.2256162721732078 0.8214998837843779 1.0 1.0 3 Q10713 1 +Kinetochore organization 0.3256608683675156 0.225266752532507 0.8217717626068581 1.0 1.0 11 Q9H3R5,Q9BS16 2 +Negative regulation of mrna 3 end processing 0.3827265029635903 0.225232087605193 0.8217987283808585 1.0 1.0 6 Q5VTR2,Q6PD62,Q6PJT7,O00267,O75150 5 +Regulation of t cell activation 0.265043984806128 0.2239925288309206 0.8227631166768106 1.0 1.0 41 Q08722,P30825,Q9HCL2,O96005,Q9Y255,Q9NUQ9 6 +Cytoskeleton dependent intracellular transport 0.2922748724685985 0.2211881178917738 0.8249459606968856 1.0 1.0 68 Q8WXH0,Q15154,O75381,O43707,Q8TD16,Q9UH99,P05067,P07196,Q5SNT2,P62820,O95295,Q9Y2T2,P23246,O60313,P11279,Q14203,Q9UBK9,Q9Y366,P78537,Q96ED9 20 +Synaptic vesicle exocytosis 0.2887786893217732 0.2210731745786119 0.8250354570917198 1.0 1.0 19 O95295,Q7L0J3,Q12846,P16615,Q06787,O95721,Q9P253 7 +Muscle contraction 0.2708062804463249 0.2189892554650361 0.8266584175379372 1.0 1.0 46 P16615,P50402,P10253,Q96PU5,P20020,Q9HD47,P23634,P42345 8 +Regulation of animal organ morphogenesis 0.3345831372288079 0.2188417491600101 0.8267733239017196 1.0 1.0 10 Q8TAA9 1 +Response to corticosteroid 0.2666412153348425 0.2154073658480206 0.8294497276841302 1.0 1.0 30 P07196,P16435,P04062,P20020,Q99758,P16278 6 +Cellular response to carbohydrate stimulus 0.2670164514446406 0.214880263841275 0.8298606726476339 1.0 1.0 25 Q16822,Q12846,Q8N183,O95563,Q5KU26,Q15043,Q8N5M9,Q96RR1 8 +Negative chemotaxis 0.4326471309096535 0.2145333303580697 0.830131178087564 1.0 1.0 4 P06756 1 +Cellular response to vitamin d 0.431923748048748 0.2125476790478448 0.8316797848957218 1.0 1.0 4 P20020 1 +Cellular response to vitamin 0.431923748048748 0.2125476790478448 0.8316797848957218 1.0 1.0 4 P20020 1 +Regulation of adaptive immune response 0.27510668553698 0.210885969291909 0.8329762528082745 1.0 1.0 23 P02786,P01889,P04439,O96028,Q9NUQ9,O15400,Q96FV9 7 +Negative regulation of cell projection organization 0.2642832005111317 0.2092266355711025 0.83427132036531 1.0 1.0 33 Q96G23,Q9NR77,Q9NQC3,Q9NQX7,P08670,Q8N5V2 6 +Regulation of phagocytosis 0.286544688845573 0.2076117117276264 0.8355321589805949 1.0 1.0 19 Q08722,P06756,Q12907,Q8WTV0,Q06481,Q08431 6 +Positive regulation of neuron projection development 0.2655848642911999 0.2070183849779788 0.8359955003712172 1.0 1.0 30 Q14108,Q32P28,O15031 3 +Galactose metabolic process 0.4294822438865036 0.2059024194042354 0.8368671355325621 1.0 1.0 4 P16278 1 +Regulation of establishment of protein localization to mitochondrion 0.2859898853877077 0.2042974421928329 0.8381210686578977 1.0 1.0 19 Q9Y371,O14737,O95429,Q9H300,P49257,Q9UII2 6 +Regulation of protein targeting 0.2648602113668298 0.201295582348207 0.840467456646107 1.0 1.0 30 Q9Y371,O14737,Q9Y3D6,P27105,Q9H300,P49257 6 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.320114732578047 0.2009065079895713 0.8407716788306856 1.0 1.0 11 P45880,P05141 2 +Regulation of response to wounding 0.2772923274103716 0.2003559697490508 0.8412021922983057 1.0 1.0 22 P46108,Q16625,Q96G23,Q04656,P04083,P10586,P42345 7 +Visual behavior 0.3494553894709425 0.2000923746450244 0.8414083369291612 1.0 1.0 7 P05067 1 +Regulation of dna damage response signal transduction by p53 class mediator 0.3198579567056046 0.1997977708638472 0.8416387447716271 1.0 1.0 11 O75844 1 +Purine nucleoside metabolic process 0.3291913998394383 0.1994245397961241 0.8419306660138495 1.0 1.0 9 O60725,Q13126 2 +Negative regulation of signaling 0.2269732617034631 0.1992392630471665 0.8420755875824835 1.0 1.0 225 P06756,Q9NPR9,P09601,Q05D32,Q7LG56,P02545,Q9Y255,Q9BRG1,Q9NUQ9,O76024,P23634,Q96FV9,O95881,O43657,P46934,Q92896,P98164,P04062,Q07954,P22413,Q86TM6,Q06787,Q07021,P05141,P62942,Q99538,Q9H3K2,P30153,Q16836,P57105,Q99623,P50402,P48729,Q7Z739,O60313,Q8N5M9,P04035,P61289,Q86UT6,Q9H300,Q07820,P42345,Q8N0X7,Q08722,P45880,Q10713,Q96HY6,Q8TBX8,Q8N2F6,Q9P0J0,P78318,Q96C57 52 +Regulation of mitotic recombination 0.5386350817822998 0.1990587838530773 0.8422167616968457 1.0 1.0 3 Q92878,P18074 2 +Positive regulation of smooth muscle cell apoptotic process 0.5386207535088967 0.1990269420956485 0.8422416694262151 1.0 1.0 3 P98175 1 +Negative regulation of single stranded viral rna replication via double stranded dna intermediate 0.3984198645598162 0.1986309291503324 0.8425514576977773 1.0 1.0 5 Q9Y6X9,Q13263,Q9UK61,Q9NRW3 4 +Regulation of neurotransmitter transport 0.289172888357794 0.1980688178980765 0.84299122119962 1.0 1.0 16 O95295,P16615,Q06787,O75955,Q9P253 5 +Anterior posterior pattern specification 0.2768870017018296 0.1977049397923427 0.8432759246093662 1.0 1.0 22 Q5T9L3,Q8N2A8,O75787,Q15363,Q12849 5 +T cell homeostasis 0.3740802497571064 0.1962353711134409 0.8444259440898869 1.0 1.0 6 Q9HCL2 1 +Axo dendritic protein transport 0.4253878702397587 0.1949561708172618 0.8454272597977168 1.0 1.0 4 P33176,P78559,Q14168 3 +Protein localization to presynapse 0.4253878702397587 0.1949561708172618 0.8454272597977168 1.0 1.0 4 P33176,P78559,Q14168 3 +Regulation of pinocytosis 0.3965695630779153 0.1931894465431032 0.8468106034901288 1.0 1.0 5 P50897 1 +Positive regulation of pinocytosis 0.3965695630779153 0.1931894465431032 0.8468106034901288 1.0 1.0 5 P50897 1 +Regulation of insulin secretion 0.2837393551246099 0.1909732783796422 0.8485465286027307 1.0 1.0 19 Q16822,Q16836,Q12846,O95563,P53985,Q8N5M9,P50416 7 +Multicellular organism growth 0.2630959213633033 0.1903974496645037 0.8489976959942203 1.0 1.0 31 O75844,O95470,O15020,Q9HCL2,Q15363,P05067,P42345 7 +Anoikis 0.3268843870434588 0.1901703616440356 0.8491756352728141 1.0 1.0 9 Q07820 1 +Aorta development 0.3262948932362305 0.1878261993887322 0.8510128971304465 1.0 1.0 9 P98164,Q96AY3 2 +Regulation of dna methylation 0.31699730729355 0.1875627456307147 0.85121943254531 1.0 1.0 11 O75844,Q8NB78,Q03164,Q96KQ7 4 +Protein transport along microtubule 0.3944695259593699 0.1870816270851081 0.8515966332932385 1.0 1.0 5 P33176,P78559,P04792,Q14168 4 +Positive regulation of nik nf kappab signaling 0.3059841272428724 0.1857574358508463 0.8526349847728965 1.0 1.0 12 P05067,O43707 2 +Protein ufmylation 0.3937492871577728 0.1850036538023662 0.8532261697255765 1.0 1.0 5 O94874,Q96HY6 2 +Positive regulation of rna binding 0.3935873679730453 0.1845376841830257 0.8535916670562738 1.0 1.0 5 Q06787 1 +Positive regulation of protein k63 linked ubiquitination 0.5370735833098546 0.1844722549922983 0.8536429909344578 1.0 1.0 2 P61088 1 +Secretory granule organization 0.3701768213639187 0.1835816168175581 0.8543416856588273 1.0 1.0 6 P78537 1 +Response to topologically incorrect protein 0.2767620709440992 0.1814603343280601 0.8560062648717142 1.0 1.0 55 Q9Y4P3,P48723,P07900,Q9GZP9,Q96HY6,Q13438,Q92905,Q9BUN8,Q15629,P46379,P57088,Q15363,O94874,Q96CS3,O76024,Q6NTF9,Q13217,Q7Z2K6 18 +Hindbrain morphogenesis 0.2975476999831521 0.1804614383258708 0.8567903251141726 1.0 1.0 13 Q04656,O15020,P04062,Q15058,Q96D53 5 +Inflammasome complex assembly 0.4188998589562693 0.1781264269531548 0.858623688199851 1.0 1.0 4 Q9H6R0,O00571,P19525 3 +Pinocytosis 0.324074865179828 0.1759892842340648 0.86030236099749 1.0 1.0 10 P50570,Q9BZG1,P50897,Q06481 4 +Positive regulation of receptor mediated endocytosis 0.3035403468238188 0.1749246532318328 0.8611388384529028 1.0 1.0 12 P50570,P50897,Q06787 3 +Cell activation involved in immune response 0.2634615114547285 0.1745195853305078 0.8614571400786568 1.0 1.0 44 P02786,Q12846,Q04656,P09601,Q07954,Q99584,O96028,P11279,Q9NRA0,P05067,Q96FV9,P42345 12 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.2604235876910962 0.1728859312936633 0.862741090332815 1.0 1.0 32 P02786,P01889,P04439,O96028,Q9NUQ9,O15400,Q07021,Q96FV9,P42345 9 +Calcineurin mediated signaling 0.3414686682465168 0.1714273129209933 0.8638877800419074 1.0 1.0 7 P23634 1 +Inositol phosphate mediated signaling 0.3414686682465168 0.1714273129209933 0.8638877800419074 1.0 1.0 7 P23634 1 +Regulation of calcineurin mediated signaling 0.3414686682465168 0.1714273129209933 0.8638877800419074 1.0 1.0 7 P23634 1 +Synaptic vesicle transport 0.2954281658365575 0.1706410769787669 0.8645059968405251 1.0 1.0 13 O95295,Q9Y2T2,P50570,Q96A57,P78537 5 +Regulation of jnk cascade 0.2838830851159486 0.1701305084234528 0.864907501001436 1.0 1.0 16 Q92905,P05067,Q969S3,O00560 4 +Microtubule nucleation 0.280063262139465 0.1696337138724681 0.8652982069525437 1.0 1.0 19 Q9BSJ2,Q14203,Q9HD47,Q9UGJ1 4 +Cellular component assembly involved in morphogenesis 0.2606765384183296 0.1691508212327425 0.8656780112520297 1.0 1.0 25 Q13045,Q16880 2 +Regulation of mitochondrial dna replication 0.5238333583748122 0.167496340447981 0.8669795267549831 1.0 1.0 3 Q9UJZ1 1 +Regulation of heart rate 0.301672067230461 0.1667623504585628 0.8675570437708149 1.0 1.0 12 Q9HD47,P16615 2 +Regulation of neuronal synaptic plasticity 0.3237185052243938 0.1659961266550913 0.8681599983666437 1.0 1.0 8 P05067 1 +Protection from non homologous end joining at telomere 0.4138222849083091 0.1654046232307552 0.8686255149862097 1.0 1.0 4 Q9UBB9,Q9NYB0,P18887 3 +Adipose tissue development 0.3116169355794984 0.1651456392846969 0.8688293511975105 1.0 1.0 11 O15173,P43490,Q8N0X7 3 +Cellular modified amino acid metabolic process 0.2779344723135304 0.1649516500680845 0.8689820382917139 1.0 1.0 58 P23786,Q8NBM8,Q9H2D1,O15217,Q9UJ14,O60725,Q9UHG3,P00374 8 +Regulation of mrna binding 0.3642010288249914 0.1647550991710624 0.8691367466436266 1.0 1.0 6 Q06787 1 +Animal organ morphogenesis 0.2985613434086191 0.1646809941884759 0.8691950771604526 1.0 1.0 103 Q15363,Q8NBN7,Q9NQC3,Q16706,Q92896,O95470,P98164,P04062,P54802,Q96A65,Q15418,P62942,Q9UID3,Q9NX62,Q99623,P10253,Q15643,O75569,P53701,P42345,O75844,P16435,Q6P4Q7,Q8TAA9,Q13586,O96028,P09493,Q8N5W9,P35613 29 +Positive regulation of cell size 0.5216149018612976 0.162998020515968 0.8705199932281744 1.0 1.0 3 Q04656 1 +Positive regulation of dendritic spine development 0.3108795178129046 0.1621350983320222 0.8711994673792725 1.0 1.0 11 Q14444,Q9UQB8,P61160,Q14012,Q06787 5 +Cellular response to copper ion 0.4123170016937562 0.161710017587955 0.8715342154829138 1.0 1.0 4 P05067 1 +Extracellular matrix assembly 0.3629875014534085 0.1610140521238711 0.8720823330558485 1.0 1.0 6 Q96AY3 1 +Mitochondrion distribution 0.4118822197428157 0.160649465418709 0.8723694930731765 1.0 1.0 4 O75153 1 +Regulation of hormone secretion 0.2634415969465588 0.1589098163963685 0.8737399266089259 1.0 1.0 24 Q16822,Q16836,Q12846,Q8N183,O95563,Q9UNH7,P53985,Q8N5M9,P50416,P04083 10 +Response to camp 0.3099733788805846 0.1584565171758929 0.8740970819812084 1.0 1.0 11 P05067,P35613 2 +Mammary gland epithelium development 0.3211666718779001 0.1566004799313764 0.8755597242814539 1.0 1.0 8 Q99623,Q9NQC3 2 +Negative regulation of epithelial cell migration 0.2991368297421746 0.1558545807665847 0.8761476470112477 1.0 1.0 12 P57105 1 +Axis specification 0.2916574803813712 0.1535268156133789 0.8779828451744236 1.0 1.0 13 Q15363,Q5T9L3,Q8N2A8 3 +Mannose metabolic process 0.4088038091349348 0.1532252314172158 0.8782206608202461 1.0 1.0 4 O00754 1 +Alternative mrna splicing via spliceosome 0.2555112386602619 0.150321595503167 0.8805108958257402 1.0 1.0 40 P52756,P51116,P51114,Q9UHX1,P23246,P98175,Q06787 7 +Cellular response to external stimulus 0.2743587639445212 0.1502788775461239 0.8805445970086598 1.0 1.0 56 Q9Y371,Q8TB36,P54619,Q9Y4P3,P21964,P09601,P13473,P04062,P49327,P20020,Q9P2J5,Q96QD8,Q96KQ7,P42345 14 +Myeloid leukocyte activation 0.2584009168763146 0.1501861453045214 0.8806177563602962 1.0 1.0 29 P05067,P09601,Q9NRA0,Q99584 4 +Granulocyte chemotaxis 0.2776260398798746 0.1500403507889975 0.8807327802513756 1.0 1.0 17 O00429,Q92538,Q8NE86,P04083,Q07021,P35613 6 +Protein k29 linked ubiquitination 0.5149464184997328 0.149845480444002 0.8808865262139709 1.0 1.0 3 Q15386,Q16763 2 +Cd4 positive alpha beta t cell differentiation 0.3591062401983096 0.1492384405709879 0.8813654884288351 1.0 1.0 6 P42345,Q04656 2 +Positive regulation of epithelial cell migration 0.2568969784372441 0.1491398781392255 0.8814432595459325 1.0 1.0 33 P09601,Q8WTV0,Q9NQC3,P42345,P06576 5 +Negative regulation of response to biotic stimulus 0.2656514620932715 0.1482156643113728 0.8821725700209635 1.0 1.0 23 O43657,P46108,P01889,P04439,Q86UT6,Q07021 6 +Regulation of calcium ion transmembrane transporter activity 0.2768474073279316 0.1459853441958613 0.8839329581104409 1.0 1.0 17 Q13586,P62942 2 +Nucleobase containing compound transport 0.2941914714248421 0.1437478676166136 0.8856995708031392 1.0 1.0 116 Q15388,P33897,L0R6Q1,Q8TD16,Q8N1F7,Q9BTX1,O00400,Q96FV9,O15439,Q96PU8,Q6I9Y2,Q7Z3B4,Q8TB61,O43808,Q9H2D1,P12236,P82979,Q06787,P05141,Q8NFH5,Q9HC21,P41208,P12235,Q08722,Q6NUK1,Q9BSK2,Q8NFH4 27 +Neuronal stem cell population maintenance 0.3572239460405345 0.1436326910863446 0.8857905245586206 1.0 1.0 6 Q15154,Q9BXW9 2 +Lamellipodium assembly 0.2680308869965569 0.1415950306672557 0.8873998923368451 1.0 1.0 22 P53365,Q16625,Q04656,Q9H4A6,P50570,P42345 6 +Cardiac ventricle morphogenesis 0.316884651288934 0.1411970876131804 0.8877142467749088 1.0 1.0 8 P09493,P62942 2 +Regulation of myotube differentiation 0.3563262188054883 0.140983531868209 0.8878829520582279 1.0 1.0 6 P42345,Q9BYT8 2 +Negative regulation of lipid transport 0.4031238233688576 0.1399200919979293 0.8887231263319233 1.0 1.0 4 Q9Y3D6 1 +Positive regulation of vesicle fusion 0.4031029619181777 0.1398721716886538 0.8887609888854926 1.0 1.0 4 P07355,P04083,P31751 3 +Leukocyte tethering or rolling 0.4028208744710693 0.1392248790619643 0.889272449309197 1.0 1.0 4 Q9H4A6,P35612,P05556 3 +Positive regulation of endocytosis 0.2638689311299911 0.1368755886378468 0.8911291346509522 1.0 1.0 23 P50570,Q96PU5,Q07954,P50897,Q06787,Q06481,O75955 7 +Multivesicular body organization 0.2771964380111383 0.1362872160486583 0.8915942297021022 1.0 1.0 16 Q9HD42,Q8WUX9,Q9UQN3,Q92783,Q9Y3E7,Q9BRG1,O14964 7 +Convergent extension 0.5111361714124794 0.1347075412643449 0.8928431104750993 1.0 1.0 2 Q13263 1 +Lung associated mesenchyme development 0.5111361714124703 0.1347075412643289 0.892843110475112 1.0 1.0 2 P35222 1 +Regulation of rrna processing 0.3148828014684981 0.1341545429958445 0.8932803703303076 1.0 1.0 8 Q8IWA0,Q15061,Q8TED0,Q9BVS4,Q9P275,O43709,Q9H583 7 +Genomic imprinting 0.5105723146321015 0.1337286767396887 0.8936171280727865 1.0 1.0 2 Q13263 1 +Regulation of genetic imprinting 0.5105723146321015 0.1337286767396887 0.8936171280727865 1.0 1.0 2 Q13263 1 +Response to cobalt ion 0.3991388408041756 0.1308929042388149 0.8958600279858968 1.0 1.0 4 Q9NQ88 1 +Cardiac septum morphogenesis 0.3289860846582463 0.1294119997346614 0.8970316531096385 1.0 1.0 7 O96028 1 +Neuron differentiation 0.227147760075307 0.1286999569584027 0.8975950694693153 1.0 1.0 239 Q96G23,O00264,Q9NZJ7,O14949,Q32P28,Q9Y6M7,P50897,Q16880,Q02790,Q9NQC3,P05067,P23634,Q92859,P00374,P07196,P46934,P04062,P54802,Q16739,Q9NR77,Q06787,Q9NQX7,O75503,Q8N5V2,O75312,O15031,Q96PU5,Q15643,P42892,P08670,P30536,Q9NV96,Q14108,P35613 34 +Ventricular cardiac muscle tissue morphogenesis 0.3285866343459445 0.1281257620068725 0.8980494489357456 1.0 1.0 7 P09493,P62942 2 +Muscle organ morphogenesis 0.3285866343459445 0.1281257620068725 0.8980494489357456 1.0 1.0 7 P09493,P62942 2 +Cardiac muscle tissue morphogenesis 0.3285866343459445 0.1281257620068725 0.8980494489357456 1.0 1.0 7 P09493,P62942 2 +Smooth muscle contraction 0.3022065866106745 0.1278856613389053 0.898239458460111 1.0 1.0 11 P23634 1 +Torc1 signaling 0.3130212413403935 0.1276975362679099 0.8983883399042683 1.0 1.0 8 P42345 1 +Apoptotic signaling pathway 0.2671622193211982 0.1272047566652228 0.8987783406927015 1.0 1.0 151 P06756,Q969S3,P09601,Q7LG56,P02545,Q9Y255,O76024,P51572,O95881,P07237,Q96A26,O95470,Q15118,P46379,P30154,Q86TM6,Q9NQX7,P05141,Q9H3K2,P30153,P23246,O60313,P61289,Q9H300,Q07820,Q9UII2,Q9NR28,O14737,P45880,Q12846,Q9Y3D6,Q8N2F6,O00429,Q9P0J0 34 +Trophoblast cell migration 0.5026710196707681 0.1270928363726368 0.8988669212316871 1.0 1.0 3 Q07021 1 +Response to vitamin d 0.3717857262933175 0.1258957594089013 0.8998144394699366 1.0 1.0 5 P20020 1 +Positive regulation of reactive oxygen species biosynthetic process 0.3713111400243136 0.1247121089104036 0.9007514707236124 1.0 1.0 5 P00403 1 +Regulation of dna binding 0.2546084384227427 0.1225869976614517 0.9024341511426536 1.0 1.0 28 O75844,P09601 2 +Digestive system development 0.2772977071407856 0.1220424111118637 0.9028654300828868 1.0 1.0 14 Q5T9L3 1 +Protein catabolic process 0.2417206572758143 0.1212771068921006 0.9034715522141497 1.0 1.0 305 Q9UBS8,Q9UBU6,Q16740,P13473,Q9UJX4,P28070,P50897,Q9BRG1,Q96CS3,O76024,Q96TA2,P51572,Q4ZIN3,Q96E52,Q8N511,P46934,Q9HD42,P98164,P04062,Q96A33,Q15058,Q07954,Q9BUN8,Q9UL46,Q8NF37,Q9UNS2,P46379,Q9UPT9,Q86TM6,Q06787,Q6ZXV5,O14773,O75503,Q9UIQ6,Q99538,P53350,P49721,Q5VYK3,P28072,P48729,Q96PU5,Q96RL7,P04035,P61289,Q9UG56,Q9UHG3,Q9P0T7,Q9UII2,P42345,P10619,O75844,Q13190,Q16850,Q8NBM8,Q9GZP9,O00231,Q96HY6,Q13438,Q9H2J4,Q9NUJ1,O00560,P27824,Q9P0J0,Q9Y3E7,O14964,Q9UBV2,Q6NTF9,P54727,Q13217,O15372,O75150 71 +Copii coated vesicle cargo loading 0.3094894926715819 0.1211501838002844 0.9035720809483984 1.0 1.0 10 Q9NR31,Q5JRA6 2 +Regulation of peptide transport 0.27012442138757 0.1208393174852585 0.9038183074235452 1.0 1.0 20 Q16822,Q16836,Q12846,O95563,P53985,Q8N5M9,P50416 7 +Regulation of cell activation 0.2880626144598241 0.1202830026063952 0.9042589683038936 1.0 1.0 78 Q08722,Q9BWH2,P09601,P30825,Q9HCL2,O96005,Q9Y255,O96028,P11279,Q9NUQ9,P04439,Q96FV9,Q15418 13 +Tyrosine metabolic process 0.5023963913166241 0.1200259922916851 0.9044625579261544 1.0 1.0 2 P16930 1 +Positive regulation of protein targeting to membrane 0.2901091651872202 0.1186392207381906 0.905561191118915 1.0 1.0 12 P27105 1 +Positive regulation of peptidyl threonine phosphorylation 0.3254268897027297 0.1180820229744809 0.9060026673777176 1.0 1.0 7 P05067 1 +Post translational protein modification 0.2898224308397979 0.1174998959466498 0.9064639264957082 1.0 1.0 12 O60725,Q32P28,P46977 3 +Regulation of homophilic cell adhesion 0.5007048209754914 0.1173052448914761 0.9066181689062028 1.0 1.0 2 Q9P273 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.2726683930830279 0.1143504463917858 0.9089599942868264 1.0 1.0 16 Q92896,P62942 2 +Carbohydrate transport 0.2634875368828836 0.1142320930535382 0.9090538118371096 1.0 1.0 22 Q16625,L0R6Q1,P52789,Q06481,Q96AA3 5 +Negative regulation of biomineralization 0.3669340189418977 0.1139867580282122 0.9092482905848802 1.0 1.0 5 Q8N5W9 1 +Negative regulation of extrinsic apoptotic signaling pathway 0.2525764429951486 0.1137551518670092 0.9094318913592871 1.0 1.0 25 P09601,P06756,Q07820,P61289 4 +Cytoplasmic pattern recognition receptor signaling pathway 0.2699338095252471 0.1137209209915117 0.9094590275559248 1.0 1.0 19 Q07021,O43657,Q86UT6,Q99623 4 +Peptidyl lysine dimethylation 0.3462130809496561 0.112247714931631 0.91062699714699 1.0 1.0 6 Q03164 1 +Attachment of mitotic spindle microtubules to kinetochore 0.3083250908946028 0.1118080986451464 0.9109755660011908 1.0 1.0 8 Q96DB5,Q9BZD4 2 +Small rna loading onto risc 0.3453120515790784 0.1097876506592822 0.912577785182914 1.0 1.0 6 Q5KU26 1 +Muscle cell cellular homeostasis 0.3440649814760123 0.1064101989438179 0.9152569014355154 1.0 1.0 6 P10253 1 +Ribonucleoprotein complex disassembly 0.3634146172600861 0.1056152761116885 0.9158876039588456 1.0 1.0 5 P33176,Q14562 2 +Positive regulation of membrane permeability 0.2804690606648935 0.1055493636920453 0.9159399021466128 1.0 1.0 13 P45880,P05141 2 +Amyloid beta clearance 0.2867547198549097 0.1054791804644173 0.9159955894055378 1.0 1.0 12 P98164,Q16850,P04035 3 +Neuroinflammatory response 0.3628668171557548 0.1043325777638394 0.916905425663674 1.0 1.0 5 Q13315,P53634,P05556,P16885 4 +Cellular response to fatty acid 0.3628668171557491 0.104332577763826 0.9169054256636846 1.0 1.0 5 P13010,P50416,P11802,Q15120 4 +Positive regulation of chemokine c x c motif ligand 2 production 0.4919650408796288 0.1038673572585189 0.9172746120893132 1.0 1.0 2 P09429 1 +Chemokine c x c motif ligand 2 production 0.4919650408796288 0.1038673572585189 0.9172746120893132 1.0 1.0 2 P09429 1 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.3043672449135781 0.1032530193167271 0.91776216140516 1.0 1.0 10 P62942 1 +Regulation of b cell differentiation 0.4911192557090612 0.1026216502066195 0.9182632591770648 1.0 1.0 2 Q5JVF3 1 +Regulation of nervous system development 0.2763869074958224 0.1019724518263834 0.918778541333536 1.0 1.0 64 Q15154,P07196,P55209,Q96G23,O75312,O75746,O15031,P98164,P30536,Q15058,Q06481,Q9NQC3,Q16706,P42345,Q8N0X7 15 +Peptidyl lysine monomethylation 0.490555398928684 0.1017965109518331 0.9189181951220762 1.0 1.0 2 Q9H9B1 1 +Extracellular vesicle biogenesis 0.3037665968186133 0.1012023855239982 0.9193898030686892 1.0 1.0 10 Q92905,O14964,Q9Y3E7,O00560 4 +Positive regulation of nf kappab transcription factor activity 0.2512244928215439 0.1000454737187756 0.920308223711016 1.0 1.0 31 Q86UE4,Q96HY6 2 +Body morphogenesis 0.303387610485236 0.0999137490769615 0.9204128007884044 1.0 1.0 10 O95470 1 +Pronephros development 0.4891457569777392 0.0997522884870795 0.9205409873118776 1.0 1.0 2 O15078 1 +Negative regulation of transcription by competitive promoter binding 0.4863264730758539 0.0957433871294324 0.9237243812135584 1.0 1.0 2 P35232 1 +Negative regulation of amyloid fibril formation 0.3392605136889589 0.0936976058902575 0.9253493721348924 1.0 1.0 6 Q99471,Q9NQP4,Q9UHV9,P01130,O15212 5 +Regulation of system process 0.2709174871994048 0.0936010115638246 0.9254261060321988 1.0 1.0 59 O75844,O75746,P16615,P10253,P04062,P20020,Q9HD47,Q06787,P05067,P23634,P09493,P42892 12 +Cellular response to heat 0.2504571534190908 0.0934413407727022 0.9255529489789178 1.0 1.0 30 P09601 1 +De novo protein folding 0.2662834076924061 0.0926620229468244 0.9261720684553676 1.0 1.0 18 P62942 1 +Positive regulation of wnt signaling pathway 0.249752122564702 0.092526953454862 0.9262793773110536 1.0 1.0 26 Q9P0T7,Q5T9L3,Q9H2V7 3 +Positive regulation of leukocyte chemotaxis 0.28328768160176 0.0922697433037839 0.9264837271407176 1.0 1.0 12 Q07021,O00429 2 +Appendage development 0.2678875833626044 0.0920866584940379 0.9266291883898758 1.0 1.0 16 Q9NX62 1 +Genitalia development 0.3385908719600116 0.091963712967642 0.926726870234284 1.0 1.0 6 Q15392 1 +Protein maturation 0.2865539150282745 0.0917457555030495 0.9269000430319598 1.0 1.0 81 P67812,O75787,O76024,Q8TAD4,Q96TA2,Q15392,Q96E52,O75976,Q9H9S5,Q92896,Q15005,Q9NRN7,O75503,P62942,Q99538,O95295,Q9UG56,Q9UJZ1,Q9H300,P42892,O75844,Q9Y366,Q92542,Q10713,Q969M3,Q2T9J0 26 +Positive regulation of biomineralization 0.4808906511129286 0.0913984233284186 0.9271760145089768 1.0 1.0 3 P20020 1 +Growth 0.2151057112684781 0.0913104642276126 0.9272459034742784 1.0 1.0 184 Q9NZJ7,Q9BTE7,P50897,Q15363,O76024,Q9NQC3,P05067,Q9NVI7,O95470,O95684,Q15418,P07602,P51812,P30153,O75312,Q96PU5,Q9HCL2,Q7Z4V5,O14681,O75844,P16435,Q9GZP9,Q9BSK2,Q8N2F6,Q9P0J0 25 +Primary amino compound metabolic process 0.4799566306167904 0.090000970186606 0.928286443861528 1.0 1.0 3 Q9NZC3 1 +Morphogenesis of embryonic epithelium 0.2494766878341108 0.0885912124090281 0.9294067921064312 1.0 1.0 27 O15031,P98164,O60313,P11233,Q15363,Q12849 6 +Intrinsic apoptotic signaling pathway 0.285683275435283 0.0881953641548217 0.9297214018292674 1.0 1.0 80 Q9NR28,P07237,P45880,Q969S3,Q9Y3D6,Q8N2F6,P09601,Q7LG56,O60313,Q15118,Q9P0J0,Q86TM6,O76024,Q07820,Q9H300 15 +Inositol phosphate catabolic process 0.3783361048184381 0.0879523917726615 0.9299145152955096 1.0 1.0 4 Q9NX62 1 +Regulation of neural precursor cell proliferation 0.2691827032159843 0.0869292063688381 0.930727784063082 1.0 1.0 14 Q06481,P98164,P55209 3 +Positive regulation of rrna processing 0.3147939017504315 0.0860213533294449 0.9314494426392634 1.0 1.0 7 Q8IWA0,Q15061,Q8TED0,Q9BVS4,O43709,Q9H583 6 +Muscle cell apoptotic process 0.2814563487886146 0.0854557085657583 0.9318991060566082 1.0 1.0 12 P09601 1 +Very low density lipoprotein particle assembly 0.4787144065407596 0.0854440212882053 0.931908397172556 1.0 1.0 2 O95573 1 +Prenylation 0.3754583921015492 0.0825698229004272 0.9341935971496044 1.0 1.0 4 P49356,P53611,P49354 3 +Response to l glutamate 0.3744996529301407 0.0808067286117186 0.9355956569137096 1.0 1.0 4 Q9UQB8,O94874 2 +Negative regulation of atp metabolic process 0.2801067857932058 0.0805072765305152 0.9358338091878476 1.0 1.0 12 O75746,Q9Y3D6 2 +Glial cell development 0.2575345224878234 0.0799450711146511 0.9362809429555964 1.0 1.0 22 P05067,P08670 2 +Cell cycle dna replication initiation 0.3324865932825301 0.0765902730795225 0.9389494971818876 1.0 1.0 6 P33993,P49736,Q9BRX5,P09884,P33991 5 +Suppression of viral release by host 0.3322043465989288 0.0758983781169903 0.9394999472145094 1.0 1.0 6 Q14258,Q13263,Q9Y3E7,P14373,Q12899 5 +Body fluid secretion 0.2654853875211108 0.07541655559517 0.939883287261278 1.0 1.0 15 Q9UNS2,Q13505,P00403 3 +Positive regulation of epithelial to mesenchymal transition 0.331653365083165 0.0745525538175876 0.9405707255756 1.0 1.0 6 P42345 1 +Negative regulation of establishment of protein localization to mitochondrion 0.3704705757711884 0.0735620171645852 0.9413588951289436 1.0 1.0 4 P49257 1 +Synaptic vesicle localization 0.2659090661081902 0.0734874628532322 0.9414182202934128 1.0 1.0 14 O95295,Q9Y2T2,P50570,Q96A57,P78537 5 +Regulation of transcription regulatory region dna binding 0.2717792245638538 0.0713339659902764 0.9431319631235322 1.0 1.0 13 O75844 1 +Negative regulation of lipid localization 0.3476480496824498 0.0709085970086204 0.9434705011776598 1.0 1.0 5 Q9Y3D6 1 +Response to cadmium ion 0.261435415935906 0.0708809093813826 0.9434925372609118 1.0 1.0 17 P09601 1 +Escrt complex disassembly 0.295206497889895 0.0705419120718176 0.9437623426078549 1.0 1.0 8 Q9UQN3,Q9HD42,Q8WUX9 3 +Phosphatidylinositol phosphate biosynthetic process 0.2651207146605973 0.0703139819031938 0.943943754102401 1.0 1.0 14 Q9BTU6,Q9NX62 2 +Peptidyl serine autophosphorylation 0.4654637722018679 0.0693001427948056 0.9447507120788268 1.0 1.0 2 Q13546 1 +Dendritic transport 0.329099633079309 0.0683986088112284 0.9454683292463686 1.0 1.0 6 Q14254,Q00577,P23246,P33176,Q00839 5 +Regulation of dna primase activity 0.463620981387498 0.0673046853932584 0.9463391469447155 1.0 1.0 3 P49643,Q9BRT9 2 +Cell cell adhesion mediated by cadherin 0.3283042581115529 0.0665101294596688 0.9469716934253536 1.0 1.0 6 O75955,Q07157 2 +Histone h2a acetylation 0.2847589066318447 0.0657978792613915 0.9475387446834472 1.0 1.0 11 Q9UBU8 1 +Protein dna covalent cross linking repair 0.4611155394366441 0.0641119233777537 0.9488811078968687 1.0 1.0 3 Q9Y6I9 1 +Regulation of immunoglobulin production 0.2627005865463564 0.0638069311859314 0.9491239592194898 1.0 1.0 15 O96028,Q96FV9,Q12846,Q99623 4 +Attachment of spindle microtubules to kinetochore 0.2545301854038575 0.0633453740333222 0.94949148503489 1.0 1.0 22 Q8NBT2,Q96DB5,Q9Y6D9,Q15005,Q15018,Q9BZD4 6 +Positive regulation of protein catabolic process 0.2793841289345328 0.0622171250432763 0.9503899250972448 1.0 1.0 74 Q9UBS8,P46934,Q96HY6,P98164,P04062,Q8NF37,Q96PU5,Q07954,P46379,Q13190,Q9P0J0,Q06787,Q6ZXV5,P51572,Q9UII2,Q4ZIN3,P53350 17 +Positive regulation of gliogenesis 0.2900795843855502 0.0611790399538117 0.9512166221529388 1.0 1.0 9 P98164,P30536,P42345 3 +Regulation of synaptic vesicle exocytosis 0.2746437956562381 0.0611170733147172 0.9512659720295644 1.0 1.0 12 O95295,Q9P253,Q06787,P16615 4 +Regulation of neuron projection regeneration 0.362847153722781 0.0605798994885983 0.9516937820018077 1.0 1.0 4 Q96G23 1 +Negative regulation of lipoprotein particle clearance 0.3627644569816557 0.0604442579560444 0.9518018103209072 1.0 1.0 4 P41240,Q92945,P30533 3 +Positive regulation of neuroblast proliferation 0.4570059204962035 0.060139746978667 0.9520443337250684 1.0 1.0 2 P35222 1 +Negative regulation of dendritic spine development 0.4577714834397001 0.0599678529142803 0.9521812382519784 1.0 1.0 3 Q8N5V2 1 +Negative regulation of peptidyl tyrosine phosphorylation 0.2895459192799627 0.0595845051391338 0.952486559548006 1.0 1.0 9 P30153,O95684 2 +Regulation of mitotic cytokinesis 0.4568527918781759 0.0588527267400534 0.9530694113397772 1.0 1.0 3 Q9Y2S7,P37198 2 +Aggrephagy 0.3613540197461115 0.0581478840401308 0.9536308329412776 1.0 1.0 4 Q13501,O95817,Q5T8D3 3 +Negative regulation of protein containing complex assembly 0.2484285503396835 0.0573861993628905 0.9542375561986024 1.0 1.0 43 P35611,Q9UEY8,P45880,Q13045,O15020,P04062,Q15058,Q15691,Q01082,Q02790,P16949,Q9NUQ9,P35241,Q9UBB9,Q14155,Q13813 16 +Positive regulation of cell cell adhesion 0.2438193910639812 0.0534271256869563 0.9573915928996533 1.0 1.0 34 Q08722,P30825,Q9HCL2,Q9NUQ9 4 +Response to nutrient 0.2444811225701081 0.0529123268381313 0.9578017627594164 1.0 1.0 29 Q8TB36,P16435,P09601,P30536,P53985,P20020,P21953,P42345 8 +Mating behavior 0.4515239148017183 0.0525810077323741 0.9580657496682156 1.0 1.0 3 P05067 1 +Reproductive behavior 0.4515239148017183 0.0525810077323741 0.9580657496682156 1.0 1.0 3 P05067 1 +Response to wounding 0.2841171883014468 0.0525805007928279 0.9580661535887 1.0 1.0 85 Q96G23,P09601,P04083,P00374,P10586,P55011,P38435,Q9BWH2,P07196,Q9HD42,Q8WTV0,Q86YV9,P15291,Q99623,P49257,P42345,P46108,Q16625,Q04656,Q5JRA6,P30536,Q9Y3E7,Q96AY3,P09493,P42785 25 +Regulation of retrograde transport endosome to golgi 0.4482661404003468 0.0515695116258826 0.9588717132002464 1.0 1.0 2 P53367 1 +Positive regulation of synaptic vesicle recycling 0.4479842120101566 0.0513077617020653 0.9590802833087504 1.0 1.0 2 Q9Y263 1 +Response to purine containing compound 0.256921911041037 0.0508442560915526 0.9594496251996524 1.0 1.0 17 P05067,P35613,Q96RD7 3 +Protein processing involved in protein targeting to mitochondrion 0.4494485964692523 0.0502284156859707 0.9599403676843314 1.0 1.0 3 Q10713 1 +Regulation of skeletal muscle tissue development 0.3362395442404942 0.048672029321588 0.961180666815714 1.0 1.0 5 O75955 1 +Midbody abscission 0.2854948653287482 0.0477503806607135 0.9619151819063644 1.0 1.0 9 Q9HD42,Q9Y3E7,Q8WUX9 3 +Regulation of transmembrane transport 0.2817518053100317 0.0475449653427931 0.9620788936738078 1.0 1.0 81 O75844,P05067,P46934,Q16625,O43707,P52789,Q13586,Q96PU5,Q06481,Q9HD47,P22413,P27105,P21796,Q8TAD4,P23634,Q06787,Q9NRA0,P62942 18 +Nucleoside triphosphate metabolic process 0.2581379638476865 0.0473880479686998 0.9622039546588744 1.0 1.0 52 P56385,O75746,O75964,Q7LG56,P00403,O60313,P00846,P22413,Q8IWA4,Q9NRA0,P06576,P24539 12 +Regulation of tau protein kinase activity 0.4459508185052502 0.046375941785131 0.9630106115507212 1.0 1.0 3 P07900 1 +Mitochondrial dna replication 0.2786444179617171 0.0463016251663652 0.9630698440048642 1.0 1.0 11 Q04837,Q7LG56,Q9UJZ1 3 +Establishment of sister chromatid cohesion 0.3343686781687886 0.0452561156276082 0.9639031662296786 1.0 1.0 5 Q9Y6X3 1 +Positive regulation of wound healing 0.2859091000337959 0.0441649908849291 0.9647728880365408 1.0 1.0 8 P42345,Q16625 2 +Cellular response to uv 0.242308789258544 0.0426283179372444 0.9659978215528288 1.0 1.0 27 P27544,P46934 2 +Import into nucleus 0.2743025865050246 0.0420449402253312 0.966462872652372 1.0 1.0 70 Q8NFH5,P54619,Q7Z3B4,O75312,Q99623,Q8N1F7,Q9HD47,Q92973,O15397,Q53FT3,Q06481,Q7Z4Q2,O95373,P52292 14 +Regulation of protein localization to chromatin 0.3504374162680092 0.0414565313636196 0.9669319459871202 1.0 1.0 4 Q96JH7 1 +Positive regulation of protein dephosphorylation 0.2575375365307225 0.0410707955636983 0.9672394567153408 1.0 1.0 14 P04062,P42345 2 +Maintenance of sister chromatid cohesion 0.2846653487715236 0.0408203761708077 0.9674390950610344 1.0 1.0 8 Q8IY18,Q96MF7,P41227,P06400,Q6KC79,P46100,Q9Y6X3 7 +Detection of visible light 0.3316150750520618 0.0403461774849975 0.96781713941946 1.0 1.0 5 Q15555,Q9BV73,P29992 3 +Positive regulation of torc1 signaling 0.3483779971791176 0.0385203936569278 0.969272771762633 1.0 1.0 4 Q8NFG4,Q9P2J5,Q96EE3 3 +Male meiosis i 0.432196222159587 0.038048031836711 0.9696493858633864 1.0 1.0 2 Q15645 1 +Positive regulation of protein secretion 0.2439328465411152 0.0380268205801005 0.969666297758672 1.0 1.0 24 Q16822,Q5T9L3,Q12846,Q9H4A6,O95563,O00429,P49755 7 +Negative regulation of actin filament polymerization 0.2497061084538671 0.0377185844102852 0.96991205832316 1.0 1.0 22 Q9NUQ9 1 +Calcium mediated signaling using intracellular calcium source 0.3464144005224576 0.0357829350843686 0.9714554401827292 1.0 1.0 4 Q9Y3D6 1 +Hippocampus development 0.2533955096416113 0.0345011284041474 0.972477542548994 1.0 1.0 20 P46108,P07196,O14949,Q15058,P23634 5 +Free ubiquitin chain polymerization 0.4265576543557986 0.0339475285025213 0.9729189927456728 1.0 1.0 2 Q16763 1 +Regulation of epidermal growth factor activated receptor activity 0.3277930016862701 0.0337625269719376 0.9730665180421992 1.0 1.0 5 P05067 1 +Aromatic amino acid family catabolic process 0.4262757259656102 0.0337508363116661 0.9730758405264732 1.0 1.0 2 P16930 1 +L phenylalanine metabolic process 0.4262757259656102 0.0337508363116661 0.9730758405264732 1.0 1.0 2 P16930 1 +Regulation of calcium mediated signaling 0.2804134558690495 0.0335851759468328 0.9732079434809012 1.0 1.0 9 P23634 1 +Vesicle docking involved in exocytosis 0.2818073634556689 0.0334035760531344 0.9733527579775874 1.0 1.0 10 O15498,Q7Z6M1,P61026 3 +Positive regulation of nuclear cell cycle dna replication 0.424020298844099 0.0322052777239657 0.9743083473487744 1.0 1.0 2 O95785 1 +Endosome to lysosome transport 0.2398217014690842 0.0305577352597872 0.9756222487720012 1.0 1.0 26 O95295,Q9H267,Q99523,Q9UNK0,P51149,Q9UQN3,Q96L92,Q9Y3E7,Q9H9C1,Q86VS8,Q96ED9,Q9P253 12 +Negative regulation of notch signaling pathway 0.4297800338409537 0.0303502526179265 0.9757877192180552 1.0 1.0 3 Q96TA1,Q9NWT6 2 +Import into cell 0.2409474952532056 0.0291349076466623 0.9767569953311837 1.0 1.0 30 P54709,Q15758,Q9BXP2,O75915,P98164,P30825,P31751,Q15043,P55011,Q99808,P05026,P05556,P08195,P23634,O75955,Q8TDW0,P05023 17 +Positive regulation of neuroinflammatory response 0.4186636594305061 0.0287297920247878 0.977080095570191 1.0 1.0 2 P53634 1 +Regulation of striated muscle contraction 0.2596655080044802 0.0283286376680666 0.9774000402052312 1.0 1.0 13 P05023,Q9HD47,P16615 3 +Negative regulation of sister chromatid cohesion 0.3407616361071858 0.0282372521499958 0.9774729261416846 1.0 1.0 4 Q7Z5K2,Q14674,P46100 3 +Regulation of histamine secretion by mast cell 0.4255499153976408 0.0266250932111707 0.978758758863538 1.0 1.0 3 P51809,Q9UNH7 2 +Negative regulation of intracellular protein transport 0.2640779162565956 0.0265893623459465 0.9787872578795956 1.0 1.0 12 P60604,P49257,Q9GZP9,Q13438 4 +Regulation of microtubule polymerization 0.2444863233970571 0.0244718347300429 0.980476249614154 1.0 1.0 23 Q16625,Q9HD47 2 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.411333521285596 0.0244009773872615 0.9805327687165972 1.0 1.0 2 Q13177 1 +Regulation of collagen fibril organization 0.411051592895407 0.0242439735283488 0.9806580026228892 1.0 1.0 2 Q8NBJ5 1 +Genitalia morphogenesis 0.4107696645052284 0.0240876558428576 0.9807826896774958 1.0 1.0 2 P35222 1 +Nucleus organization 0.2736325026101786 0.0239499247761287 0.9808925514747628 1.0 1.0 72 Q9UH99,Q8N1F7,P02545,Q9BTX1,Q5JTV8,Q9NQC3,Q9HD42,Q7Z3B4,Q6NUK4,Q8NBJ4,P53350,Q8NFH5,O75312,P50402,Q9BTV4,Q14203,O75844,Q86XL3,P20700,Q9Y3E7,Q9H6H4 21 +Development of secondary sexual characteristics 0.3372047084800088 0.0237407353704865 0.9810594130260406 1.0 1.0 4 P15291 1 +Regulation of cell death 0.2472453427398061 0.0235769953335847 0.981190022114518 1.0 1.0 359 P06756,O43707,P09601,Q9NS69,P50897,Q96TA2,Q9Y6C9,Q9UEE9,Q4ZIN3,Q96A26,Q13510,Q07021,Q86UE4,Q99538,P15291,Q99623,P23246,P21796,Q9NR28,O14737,P45880,Q12846,Q86XL3,Q9P0J0,Q9NQ88,Q969S3,Q9H4A6,P02545,Q9NQC3,P51572,Q15392,Q96E52,O95881,Q9HD42,Q01105,P98164,P04062,P49327,P00403,Q15058,Q07954,P30154,Q9NQX7,Q15418,Q15375,P53350,P51812,P02786,Q9HCL2,Q92905,O60313,O75569,Q07820,P12235,Q96HY6,Q99720,P52756,Q9NZJ7,Q9Y255,O76024,Q9NVI7,P07196,Q86TM6,O15118,Q9H3K2,P30153,O75312,Q12981,P98175,Q9H300,P16435,Q9Y3D6,Q8N2F6,P30536,O15269,Q7LG56,P07237,P46379,P05141,P61289,Q6NUK1,O00429,Q9NRA0,Q13217 84 +Regulation of endoplasmic reticulum tubular network organization 0.3362482369534444 0.0225643228174555 0.981997802844381 1.0 1.0 4 Q9H2M9,P57088,Q15042 3 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.2394317778519865 0.0222010468126541 0.9822875825616522 1.0 1.0 34 Q92896,P98164,Q05D32,O00560,Q8N1F7,Q07954,Q92859,Q8N0X7,P62942 9 +Positive regulation of nlrp3 inflammasome complex assembly 0.4187817258883244 0.0210490108439079 0.9832065593226678 1.0 1.0 3 Q9H6R0,O00571 2 +Histone dephosphorylation 0.4048491683112556 0.0209602969020949 0.9832773271941904 1.0 1.0 2 O95677 1 +Regulation of granulocyte chemotaxis 0.2699998132023705 0.0208070384874062 0.983399583054481 1.0 1.0 11 O00429 1 +Muscle adaptation 0.2505917687451229 0.0196984826925941 0.9842839011817904 1.0 1.0 16 P09601,P23634 2 +Cellular response to dsrna 0.2751083635177399 0.0196077826886144 0.984356255340018 1.0 1.0 9 Q5KU26,O75955 2 +Response to dexamethasone 0.2764371811853588 0.0189996019294761 0.9848414229673924 1.0 1.0 10 P04062 1 +Transferrin transport 0.3312693011674569 0.0166614813266154 0.9867066763409976 1.0 1.0 4 P02786 1 +Positive regulation of tor signaling 0.2752189884148115 0.015852856929311 0.9873517799908776 1.0 1.0 10 Q9H4A6,Q9Y4R8,Q9Y2Q5,Q96EE3,Q8NFG4,Q9P2J5,Q6IAA8,Q8N122,O15379 9 +Replication born double strand break repair via sister chromatid exchange 0.4108855047941409 0.0151191426258922 0.9879371291001828 1.0 1.0 3 P18887,O60216 2 +Gland morphogenesis 0.2727099773978917 0.0135615969320236 0.9891797428605024 1.0 1.0 9 Q15418 1 +Cellular response to xenobiotic stimulus 0.2379151739790675 0.0134046453799402 0.9893049606980971 1.0 1.0 28 O43169,O15217,P27544 3 +Endocrine process 0.314230199599475 0.0125436708797604 0.9899918611228335 1.0 1.0 5 P42892 1 +Heterotypic cell cell adhesion 0.2669386078555343 0.0123655084144602 0.990134003178285 1.0 1.0 11 Q08722,P06756 2 +Double strand break repair via break induced replication 0.2728042925727095 0.0111231606277056 0.991125184873844 1.0 1.0 8 P25205,O75419,P33993,P49736,Q14566,P33991,Q9BRT9 7 +Epithelial tube formation 0.2357339696262788 0.0109297330429006 0.9912795083753468 1.0 1.0 25 O15031,P98164,O60313,P11233,Q15363 5 +Positive regulation of endothelial cell development 0.3803213983648175 0.0108535940228708 0.9913402549206508 1.0 1.0 2 P35611 1 +Endoderm formation 0.2845849802371581 0.0101618763118759 0.9918921353235975 1.0 1.0 7 P35222,P06756,Q92541,Q6PD62,Q8N7H5,Q6P1J9 6 +Endodermal cell differentiation 0.2845849802371581 0.0101618763118759 0.9918921353235975 1.0 1.0 7 P35222,P06756,Q92541,Q6PD62,Q8N7H5,Q6P1J9 6 +Regulation of lymphocyte activation 0.2618888811352965 0.0101053208019094 0.9919372577749546 1.0 1.0 60 Q08722,P30825,Q9HCL2,O96005,Q9Y255,P04439,P11279,Q9NUQ9,O96028,Q96FV9 10 +Embryonic hemopoiesis 0.3250770436682159 0.0098278501705979 0.9921586363116932 1.0 1.0 4 Q03164 1 +Membrane to membrane docking 0.4027072758037292 0.0095990074969798 0.992341217733882 1.0 1.0 3 P26038,P15311 2 +Monocyte chemotaxis 0.2838291023178203 0.0085579327535082 0.9931718409307164 1.0 1.0 7 Q99538 1 +Hemidesmosome assembly 0.3681984775866956 0.0073012531419203 0.9941744946015568 1.0 1.0 2 Q03001 1 +Long term memory 0.3224259520451313 0.0070702412499479 0.9943588106644756 1.0 1.0 4 Q96KQ7,O43164,P01130 3 +Positive regulation of dna recombination 0.2348610113019538 0.0060954215562713 0.9951365873646898 1.0 1.0 25 Q7Z4V5,O96028,P35637 3 +Neural tube formation 0.2408973854574651 0.006020176688256 0.9951966229815732 1.0 1.0 23 O15031,P98164,O60313,P11233,Q15363 5 +Positive regulation of organic acid transport 0.3095372460496688 0.0059653517246854 0.9952403661880604 1.0 1.0 5 Q15042,P14174,P05556,P55011 4 +Gland development 0.2714586190465182 0.0056670144960371 0.9954784008296786 1.0 1.0 72 P52789,P09601,Q9NZJ7,Q02790,Q9NQC3,Q16706,Q5T9L3,Q13505,Q9UNS2,P49327,P00403,Q15418,P07602,Q16822,Q99623,P11717,P50416,O75844,Q04656,Q9Y6D9,P30536,Q86VI3 22 +Response to auditory stimulus 0.3611502678319719 0.0055984771576455 0.9955330848462998 1.0 1.0 2 Q8N2K0 1 +Negative regulation of peptide secretion 0.2984454283638476 0.0053588532211506 0.9957242742158006 1.0 1.0 6 Q8N5M9 1 +Negative regulation of hormone secretion 0.2984454283638476 0.0053588532211506 0.9957242742158006 1.0 1.0 6 Q8N5M9 1 +Microtubule polymerization 0.2365300495833071 0.0046660235745318 0.9962770653386936 1.0 1.0 35 Q16625,Q9BSJ2,Q9Y3E1,Q02790,Q9HD47,Q14203,Q96P70,Q14155,Q15691,Q9UGJ1 10 +Cellular response to oxygen glucose deprivation 0.3555117000281911 0.0044064851215409 0.9964841449320768 1.0 1.0 2 O95831 1 +Response to oxygen glucose deprivation 0.3555117000281911 0.0044064851215409 0.9964841449320768 1.0 1.0 2 O95831 1 +Dedifferentiation 0.3532562729066791 0.0039689353070626 0.996833256109666 1.0 1.0 2 Q14103 1 +Anion homeostasis 0.3080177185717227 0.0039176670013648 0.9968741619811996 1.0 1.0 5 Q9BXP2,P22413,P55011 3 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.3190409026798238 0.0036923664780033 0.9970539244886312 1.0 1.0 4 Q9P273,Q13740,P15151 3 +Modulation by host of symbiont catalytic activity 0.349591203834227 0.0033029024861807 0.9973646698919816 1.0 1.0 2 P51151 1 +Error free translesion synthesis 0.3464899915421487 0.0027807510048229 0.9977812845652128 1.0 1.0 2 Q9Y2S7 1 +Anterograde neuronal dense core vesicle transport 0.3453622779813903 0.0025998836726684 0.9979255952946482 1.0 1.0 2 P33176 1 +Dense core granule transport 0.3453622779813903 0.0025998836726684 0.9979255952946482 1.0 1.0 2 P33176 1 +Columnar cuboidal epithelial cell development 0.2688127508659058 0.0020248381638162 0.9983844139949424 1.0 1.0 8 Q9NQ88,P49327 2 +Vesicle mediated transport to the plasma membrane 0.2557161243886907 0.0018220246828216 0.9985462354405366 1.0 1.0 55 Q9BZG1,P61026,Q8N1B4,Q9H4A6,P50570,O43752,Q9H223,Q01082,Q15904,Q96A65,Q96L92,Q8N2H4,Q9H4M9,Q96KP1,Q4J6C6,Q9UID3 16 +Positive regulation of vascular associated smooth muscle cell apoptotic process 0.3391598533972338 0.0016860060183074 0.998654762465904 1.0 1.0 2 O95140 1 +Phototransduction visible light 0.3159379407616264 0.0007344855162471 0.9994139653991444 1.0 1.0 4 Q15555,O60551,P29992 3 +Programmed cell death 0.2589266324214865 0.0002327056705815 0.9998143277399074 1.0 1.0 449 P06756,O43707,P24390,P09601,Q9NS69,P52789,Q03164,Q9UHX1,Q9UDX5,P50897,Q96TA2,Q9Y6C9,Q9UEE9,O95197,Q96A26,Q13510,Q07021,Q86UE4,Q99538,P15291,Q99623,P23246,P21796,Q9UII2,O75844,Q9NR28,O14737,P45880,Q12846,Q86XL3,Q9H2J4,Q9H8M7,Q9P0J0,Q9NQ88,Q969S3,Q9H4A6,Q96KA5,P02545,Q9NQC3,P51572,Q15392,Q96E52,O95881,Q01105,O95470,P98164,P04062,P49327,Q15058,P30154,Q9NQX7,Q15418,Q15375,P53350,P51812,P02786,Q9HCL2,Q92905,O60313,O75569,O14681,Q07820,P12235,Q96HY6,Q99720,Q9UBK9,P52756,Q9NZJ7,Q9Y255,O76024,P05067,Q9NVI7,P07196,P12236,Q15118,Q86TM6,Q9H3K2,P51114,P30153,O75312,Q12981,P11279,P98175,Q9H300,Q92542,P16435,Q9Y3D6,Q8N2F6,P30536,O15269,Q7LG56,Q96FV9,P07237,P46379,Q6NUQ4,P05141,Q9Y371,P61289,P42345,O00429,Q9NRA0,Q13217 102 +Renal sodium excretion 0.3264730758387371 0.0001956090829703 0.9998439265337404 1.0 1.0 2 Q9Y5X3 1 +Positive regulation of renal sodium excretion 0.3264730758387371 0.0001956090829703 0.9998439265337404 1.0 1.0 2 Q9Y5X3 1 +Regulation of excretion 0.3264730758387371 0.0001956090829703 0.9998439265337404 1.0 1.0 2 Q9Y5X3 1 +Regulation of renal system process 0.3264730758387371 0.0001956090829703 0.9998439265337404 1.0 1.0 2 Q9Y5X3 1 +Renal tubular secretion 0.3264730758387371 0.0001956090829703 0.9998439265337404 1.0 1.0 2 Q9Y5X3 1 +G protein coupled acetylcholine receptor signaling pathway 0.3264730758387335 0.0001956090829698 0.9998439265337408 1.0 1.0 2 P29992 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5aaa0cbe0d8eb7be4688bf5651a92de196b7714e --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone mineralization involved in bone maturation", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chorionic trophoblast cell differentiation", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell migration", "Hematopoietic stem cell migration to bone marrow", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate biosynthetic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate biosynthetic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isg15 protein conjugation", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte migration involved in inflammatory response", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid catabolic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage activation involved in immune response", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell proliferation involved in kidney development", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of torc1 signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid efflux", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma cell differentiation", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet dense granule organization", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 23 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 2 signaling pathway", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone mineralization involved in bone maturation", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell proliferation involved in kidney development", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte development", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of somitogenesis", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to pheromone", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKS1A", "ANLN", "ANO10", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG2B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C17orf75", "C18orf32", "C19orf70", "C1QBP", "C2CD5", "C5orf51", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CENPH", "CENPI", "CENPK", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG1", "COG3", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM126A", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD3", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL9", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NGEF", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OTUD4", "OTUD6B", "OTULIN", "OXA1L", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "SYVN1", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFPL1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF106", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["AASDHPPT", "ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABHD10", "ABHD12", "ABRAXAS2", "ACADVL", "ACBD5", "ACOT8", "ACOX1", "ACP2", "ACP6", "ACSL3", "ACSL6", "ACTN4", "ACTR2", "ADD1", "ADD2", "ADD3", "ADPGK", "AFG3L2", "AGK", "AGPAT5", "AIFM1", "AKAP8L", "AKT2", "ALCAM", "ALDH3A2", "ALG1", "ALG11", "ANAPC1", "ANAPC4", "ANAPC5", "ANKLE2", "ANKRD13A", "ANO10", "ANXA1", "ANXA2", "AP1M1", "AP3M1", "APLP2", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGEF7", "ARL1", "ARL6IP5", "ARMC10", "ARV1", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP6V1E1", "ATP7A", "ATPIF1", "ATRX", "B4GALT1", "B4GAT1", "BAG3", "BAG4", "BAG6", "BAIAP2", "BCAP31", "BCAS3", "BCCIP", "BCKDHB", "BCS1L", "BICD2", "BLOC1S1", "BNIP1", "BRAT1", "BRD4", "BSG", "BUD23", "C12orf43", "C12orf73", "C19orf70", "C1QBP", "CAMK1", "CANX", "CAPRIN1", "CCDC134", "CCDC22", "CCDC47", "CCNB1", "CCT2", "CD47", "CDC16", "CDC37", "CDC45", "CDC73", "CDIPT", "CDK12", "CDK4", "CDS2", "CENPH", "CENPK", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFDP1", "CHCHD3", "CHMP1A", "CHMP2B", "CHMP3", "CHMP7", "CHST14", "CIRBP", "CISD1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLN5", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "CNNM3", "CNNM4", "CNPY2", "COA3", "COG1", "COG3", "COG5", "COLEC12", "COLGALT1", "COMT", "COPB2", "COPS3", "COPS4", "COPS5", "COPS7B", "COPS8", "COPZ1", "COQ8B", "COQ9", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE8", "CPT1A", "CPT2", "CRK", "CRTAP", "CSK", "CSNK1A1", "CTDSPL2", "CTNNB1", "CTR9", "CTSA", "CTSC", "CYB5B", "CYP51A1", "DAGLB", "DCAKD", "DCTN1", "DCTN2", "DCUN1D4", "DCUN1D5", "DDRGK1", "DDX17", "DDX3X", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX33", "DHX8", "DIABLO", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC3", "DNM1L", "DNM2", "DOLPP1", "DPAGT1", "DPY30", "DST", "DYM", "DYNC1LI1", "EBP", "ECE1", "ECSIT", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2AK2", "EIF2B2", "EIF3E", "EIF3H", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "ENPP1", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPS15", "ERAP1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ERP44", "ESPL1", "ESYT2", "ETFDH", "ETNK1", "EXOC2", "EXOC4", "EXOC7", "EXT2", "EYA4", "EZR", "FADS1", "FAF2", "FAH", "FAM129B", "FAM162A", "FAM208A", "FAM49B", "FAM8A1", "FANCD2", "FAR1", "FASN", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP7", "FKBP9", "FKRP", "FLCN", "FLII", "FLOT1", "FLOT2", "FMR1", "FNTA", "FNTB", "FOXRED1", "FTO", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP2", "GAA", "GALNT1", "GALNT2", "GALNT4", "GBA", "GBF1", "GDAP1", "GDE1", "GGCX", "GGT7", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLG1", "GM2A", "GNA11", "GNPAT", "GNS", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPAT4", "GPR107", "GPR108", "GRSF1", "GSTA4", "GTF2H1", "GUSB", "HACD3", "HADH", "HCCS", "HDAC3", "HDGFL2", "HDGFL3", "HEATR1", "HEATR3", "HEXA", "HEXB", "HGS", "HIF1AN", "HIKESHI", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMGB1", "HMGCR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPK", "HNRNPU", "HOOK2", "HOOK3", "HPS6", "HS2ST1", "HSD17B11", "HSD17B12", "HSP90AA1", "HSP90B1", "HSPA13", "HSPB1", "ICMT", "IFT52", "IGBP1", "IGF2R", "ILVBL", "IMMT", "IMPAD1", "INA", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP3", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "JAGN1", "JAM3", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KHSRP", "KIAA0368", "KIAA1468", "KIF14", "KIF5B", "KMT2A", "KPNA2", "KTN1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LBR", "LDAH", "LDLR", "LETM1", "LGALS3BP", "LGMN", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LRRC8A", "LRRC8C", "LYSMD3", "MACF1", "MAD1L1", "MAGED1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP3K4", "MAP4K4", "MAPRE1", "MAPRE2", "MAU2", "MBOAT7", "MCL1", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "MCU", "MCUB", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD3", "MGAT1", "MGEA5", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIF", "MIGA1", "MINDY3", "MMGT1", "MORC2", "MORF4L1", "MPC2", "MPP2", "MPP5", "MPV17L2", "MSMO1", "MSN", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "MYH10", "MYO5A", "NAA10", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NASP", "NCEH1", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEO1", "NGEF", "NIPBL", "NLN", "NLRX1", "NMT2", "NNT", "NPC1", "NPC2", "NSD2", "NSMCE2", "NUDT12", "NUDT9", "NUF2", "NUP210", "NUP35", "NUP37", "NUP54", "NUP62", "NUP93", "NUPL2", "OCIAD1", "OCLN", "OMA1", "OPA1", "OPA3", "OS9", "OSBPL8", "OSTM1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PACSIN2", "PAF1", "PAK2", "PANX1", "PARL", "PCID2", "PCK2", "PCM1", "PCYOX1", "PCYOX1L", "PDCD5", "PDCL3", "PDK1", "PDK3", "PDP1", "PECR", "PEX14", "PEX19", "PEX3", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PHKA1", "PI4K2A", "PIGG", "PIGK", "PIGU", "PIP4K2C", "PISD", "PITRM1", "PJA2", "PLA2G15", "PLAA", "PLBD2", "PLCG2", "PLD3", "PLD6", "PLIN3", "PLK1", "PLXNB2", "PMPCA", "PNPLA8", "POLA1", "POLDIP2", "PON2", "POR", "PPHLN1", "PPIL4", "PPP2R1A", "PPP2R1B", "PPP6C", "PPT1", "PPT2", "PRAF2", "PRCP", "PRELID1", "PREPL", "PRIM2", "PRKAG1", "PRKCSH", "PRKRA", "PSAP", "PSMB2", "PSMB4", "PSMB6", "PSMD11", "PSME2", "PSME3", "PTGES2", "PTPRF", "PUF60", "PURA", "PVR", "PXMP2", "QKI", "RAB10", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB3GAP1", "RAB3GAP2", "RAB5B", "RAB7A", "RAB9A", "RABEPK", "RABGGTB", "RAD21", "RAD23B", "RAD50", "RALA", "RANGRF", "RB1", "RBM10", "RBM14", "RBM3", "RBM5", "RBMX", "RDH13", "RDX", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RFLNB", "RFT1", "RHBDD2", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMND1", "RNF14", "RNF20", "RNF40", "RPN1", "RPN2", "RPS6KA1", "RPS6KA3", "RPTOR", "RRM2B", "RTF1", "RTN3", "RTN4", "S100A13", "SACM1L", "SAMM50", "SAR1A", "SARNP", "SC5D", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCO1", "SCO2", "SCP2", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC16A", "SEC62", "SEH1L", "SEL1L", "SEPT10", "SET", "SF1", "SF3A1", "SF3A3", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIL1", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SMC5", "SNAP29", "SNAPIN", "SNX2", "SNX27", "SNX5", "SNX6", "SORT1", "SPAG9", "SPART", "SPC24", "SPCS2", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRP68", "SRP9", "SRPRB", "SSBP1", "SSR1", "STAM", "STARD3", "STARD3NL", "STIM1", "STMN1", "STOM", "STOML2", "STT3A", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "SUN1", "SUN2", "SUPT5H", "SURF4", "SUZ12", "SV2A", "SYAP1", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "SYVN1", "TAF15", "TAF6L", "TAP1", "TBL2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2IP", "TEX264", "TFG", "TFIP11", "TFRC", "THOC1", "THOC7", "THRAP3", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TLCD1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOR1AIP1", "TPD52", "TPM1", "TPP1", "TPR", "TRA2B", "TRAM1", "TRAPPC11", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIP11", "TRIP13", "TSPAN10", "TSPAN6", "TSPO", "TTC19", "TTC21B", "TTC26", "TTYH3", "TUBGCP2", "TUBGCP4", "TWNK", "TXNDC12", "TXNDC15", "TYSND1", "U2AF2", "UBAP2L", "UBE2G2", "UBE2N", "UBE2S", "UBE3A", "UBE3C", "UFL1", "UGCG", "UGGT1", "UGT8", "ULBP3", "UNC119B", "UQCR10", "UQCRQ", "USP22", "USP36", "UTP15", "UXT", "VAMP7", "VANGL1", "VCL", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS33B", "VPS51", "VPS52", "WAPL", "WASHC3", "WASHC5", "WBP2", "WDR43", "WDR75", "WFS1", "WIZ", "WLS", "XAB2", "XPO4", "XRCC1", "XRCC5", "XRCC6", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YME1L1", "YTHDF3", "YWHAE", "ZADH2", "ZC3H14", "ZCCHC3", "ZFPL1", "ZMPSTE24", "ZNF24", "ZNF622", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_gocc/advanced/idx2term.json b/msigdb_gocc/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..35ff02dc21355883671c3d5a3437a0e6c4c3778d --- /dev/null +++ b/msigdb_gocc/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Organelle inner membrane", "1": "Nuclear outer membrane endoplasmic reticulum membrane network", "2": "Organelle subcompartment", "3": "Mitochondrial envelope", "4": "Endoplasmic reticulum", "5": "Intrinsic component of organelle membrane", "6": "Vacuole", "7": "Golgi apparatus", "8": "Envelope", "9": "Golgi membrane"} \ No newline at end of file diff --git a/msigdb_gocc/advanced/plot_0.png b/msigdb_gocc/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e31c6e05b383f0c00394c3dc6388bb55d425995e --- /dev/null +++ b/msigdb_gocc/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24273ebeba28141fa95a13e1de95aa87c8474da21a2d082a95a32f634ea60738 +size 218746 diff --git a/msigdb_gocc/advanced/plot_1.png b/msigdb_gocc/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..588c4be06bf687ed91e1dc69ba9f7d0a7e7fa1ff --- /dev/null +++ b/msigdb_gocc/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64a80325d4aacc1c4947a91b5f14a4c40e9a5d1b7090918036d0e741cb5d1b3c +size 227922 diff --git a/msigdb_gocc/advanced/plot_2.png b/msigdb_gocc/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..07e1f1d8bce5d8f093adc138b7d51231839912d2 --- /dev/null +++ b/msigdb_gocc/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7e16dd1fc06db4611ff555d02c88fa713ed4c94a68639df9595852b6d0007a4 +size 224615 diff --git a/msigdb_gocc/advanced/plot_3.png b/msigdb_gocc/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..2947cad27b99e4ee9ad79e336dfabd6c8decea97 --- /dev/null +++ b/msigdb_gocc/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f3d8b8b0fe444e16f688bc4e400efd1a3f6681ce911a7b37fe992aa609d8070 +size 221867 diff --git a/msigdb_gocc/advanced/plot_4.png b/msigdb_gocc/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..6d51381906c2b5187e821ae8b8c6d4d717e1c27e --- /dev/null +++ b/msigdb_gocc/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:daf5e52e854570e96f3dc7ba7d92b2cd42010e5ef066f60a37ca1a82d0267441 +size 222928 diff --git a/msigdb_gocc/advanced/plot_5.png b/msigdb_gocc/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..d1e43d0a3f1a32844411a2eb5752a9e627b1ccb0 --- /dev/null +++ b/msigdb_gocc/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:10cb6470cb8601f687a5118b6b8d3cccf70e87874f8becdaa4d7dea0cc21fb70 +size 212518 diff --git a/msigdb_gocc/advanced/plot_6.png b/msigdb_gocc/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..c1dacd483a71b4def01942f20be4295bde54b90b --- /dev/null +++ b/msigdb_gocc/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88f4f8f0a40eb0403a3d82093cf3bd34f51d50968c982896930f4e4a283a854f +size 212887 diff --git a/msigdb_gocc/advanced/plot_7.png b/msigdb_gocc/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..6e278ec4b15b05a95f4c17055cb02174c35f536f --- /dev/null +++ b/msigdb_gocc/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7eca025bdde35c0f96aa4aa44be1852239e216a2757f06c1491fdb2017986caf +size 221192 diff --git a/msigdb_gocc/advanced/plot_8.png b/msigdb_gocc/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..41031d779f86a276eeeecd9489c2bfcf66d52886 --- /dev/null +++ b/msigdb_gocc/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62968c58b5163bc22f959b8df93ae554e5085b84feffc119a0def4516b15def9 +size 221055 diff --git a/msigdb_gocc/advanced/plot_9.png b/msigdb_gocc/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..54b1444d2ed06687e2f8b69d005417c6f58f238f --- /dev/null +++ b/msigdb_gocc/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4823b9ef39114d0f7881b96246179dd4985bb0cf25b9e50db678d28a248b0dc6 +size 215910 diff --git a/msigdb_gocc/basic/idx2term.json b/msigdb_gocc/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fa4e1b0a0695d867a8f572b227dba139fb6c7114 --- /dev/null +++ b/msigdb_gocc/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Organelle inner membrane", "1": "Nuclear outer membrane endoplasmic reticulum membrane network", "2": "Organelle subcompartment", "3": "Mitochondrial envelope", "4": "Endoplasmic reticulum", "5": "Intrinsic component of organelle membrane", "6": "Vacuole", "7": "Golgi apparatus", "8": "Envelope", "9": "Golgi membrane", "10": "Membrane protein complex", "11": "Lysosomal lumen", "12": "Endoplasmic reticulum golgi intermediate compartment membrane", "13": "Intrinsic component of mitochondrial membrane", "14": "Intrinsic component of endoplasmic reticulum membrane", "15": "Intrinsic component of mitochondrial inner membrane", "16": "Azurophil granule membrane", "17": "Vesicle membrane", "18": "Mitochondrial protein containing complex", "19": "Vacuolar membrane", "20": "Trans golgi network membrane", "21": "Endosome", "22": "Intrinsic component of plasma membrane", "23": "Outer membrane", "24": "Inner mitochondrial membrane protein complex", "25": "Respirasome", "26": "Endoplasmic reticulum golgi intermediate compartment", "27": "Copii coated er to golgi transport vesicle", "28": "Vacuolar lumen", "29": "Secretory granule membrane", "30": "Outer mitochondrial membrane protein complex", "31": "Golgi cisterna", "32": "Endocytic vesicle membrane", "33": "Snare complex", "34": "Cytochrome complex", "35": "Endoplasmic reticulum tubular network", "36": "Proton transporting two sector atpase complex", "37": "Cis golgi network", "38": "Organelle membrane contact site", "39": "Nuclear envelope", "40": "Transport vesicle membrane", "41": "External side of plasma membrane", "42": "Exocytic vesicle", "43": "Nuclear inner membrane", "44": "Specific granule membrane", "45": "Apical plasma membrane", "46": "Phagocytic vesicle membrane", "47": "Basolateral plasma membrane", "48": "Organelle envelope lumen", "49": "Intrinsic component of mitochondrial outer membrane"} \ No newline at end of file diff --git a/msigdb_gocc/basic/plot_0.png b/msigdb_gocc/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ecc6816278b819031c9f3c841b292b84099df0b8 --- /dev/null +++ b/msigdb_gocc/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a5af152f4a256418ce7760d4741262eec8ab1beb17e382d08149272b025e756f +size 143889 diff --git a/msigdb_gocc/basic/plot_1.png b/msigdb_gocc/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..81473e7517d4989044d4498f4d299a02ac10406f --- /dev/null +++ b/msigdb_gocc/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29d8c30f5c11e20465e850f692f4e4dd044583c3810278656992f4d21510733f +size 149233 diff --git a/msigdb_gocc/basic/plot_10.png b/msigdb_gocc/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..35feeca18e8f6ea9056ac936bc55f3367ab5a8bc --- /dev/null +++ b/msigdb_gocc/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:032971206f73cc7f363060dace72fc7da625d02f5b12dbdb31b1d4bb8a7c9e56 +size 145880 diff --git a/msigdb_gocc/basic/plot_11.png b/msigdb_gocc/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..6d8b3afc6c5d7aec48abcc756fb263413406ba72 --- /dev/null +++ b/msigdb_gocc/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d74bdf57ee0c6a71e72bab28b5ca0901d24be1a3b376121b1047d5e4cfdad77 +size 140952 diff --git a/msigdb_gocc/basic/plot_12.png b/msigdb_gocc/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..e0fd3bd995fe5dcda446d8c43d234298aa7d0946 --- /dev/null +++ b/msigdb_gocc/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d117ddc8ee89163a0237a1ac9ded17c2da61056b27abbf9acfe203ba4bdfc779 +size 148078 diff --git a/msigdb_gocc/basic/plot_13.png b/msigdb_gocc/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..20d3d5f2b3d0e6c45a606a7ee7614de0cb2276d8 --- /dev/null +++ b/msigdb_gocc/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d366faafef41617b66ccdca8d8c9bbc154154d602bdbef607565ee6021f9992f +size 147945 diff --git a/msigdb_gocc/basic/plot_14.png b/msigdb_gocc/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..ae4eed3ffe449f75aec66ce8cd2492df8fbd9944 --- /dev/null +++ b/msigdb_gocc/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17736390d9de2f8d5f5704b292eec7fb6d90b71d981c254a5746071a97748ace +size 149971 diff --git a/msigdb_gocc/basic/plot_15.png b/msigdb_gocc/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..f44e9285c3d5288c380b3713f6cdc3e16dba591f --- /dev/null +++ b/msigdb_gocc/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:92afe2bdd817797b3a464aee6e367bbf093851780474d6ddc96529d95a8231c8 +size 147154 diff --git a/msigdb_gocc/basic/plot_16.png b/msigdb_gocc/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..359e7191afa5e30f886abe2d693d863a45bc6ff4 --- /dev/null +++ b/msigdb_gocc/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cac590cf56436d2c68a3af99eb01b15700bf69e801fba29287834ae128703231 +size 144508 diff --git a/msigdb_gocc/basic/plot_17.png b/msigdb_gocc/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..7cfb4bd404658b2698e24b7a34c8c0347e4d12b5 --- /dev/null +++ b/msigdb_gocc/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e8a0c36a3e94315bf80de323e5334efa96f8e4afa5bebfe04daddc21708601f +size 145370 diff --git a/msigdb_gocc/basic/plot_18.png b/msigdb_gocc/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..115fe2469537df4906a8aa4176cbe1d2754b7824 --- /dev/null +++ b/msigdb_gocc/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72ad9454809c6fcefb2fc3e38cabe5b4bfb7ae2c32e5ff27e77b541d28ed9a4b +size 153598 diff --git a/msigdb_gocc/basic/plot_19.png b/msigdb_gocc/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..a97bcff035ce0592e7298e89e9e4e75d5dcdffa7 --- /dev/null +++ b/msigdb_gocc/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:25178d4ae8129723e4ba1d843dc57d51bd2f9380282e93fc59476fd914c08436 +size 141155 diff --git a/msigdb_gocc/basic/plot_2.png b/msigdb_gocc/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..429ce878bab1f95d25ff809e34f0fe5e3f61bad3 --- /dev/null +++ b/msigdb_gocc/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9688e64f0c747adf766faf82fcec06558b794a40ea48d270be4c877e8a4faf04 +size 142677 diff --git a/msigdb_gocc/basic/plot_20.png b/msigdb_gocc/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..cf4bc3358d46b1329851dec30336590ea9288f06 --- /dev/null +++ b/msigdb_gocc/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:70510622b8545768d482abe6e8e171fcd36db7daff8d6635418d0981d814f1e9 +size 148267 diff --git a/msigdb_gocc/basic/plot_21.png b/msigdb_gocc/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..e0350b03e24fc68ac6696f0751f658f3e64e702c --- /dev/null +++ b/msigdb_gocc/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a0b337a91f19df58ca0dc32a79755975415a5e1979e48dc9e9fb846435e97c9 +size 140572 diff --git a/msigdb_gocc/basic/plot_22.png b/msigdb_gocc/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..134c36fff6e6f626cd461441afbb9ff621043c8d --- /dev/null +++ b/msigdb_gocc/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27ad71225eae46374397b8f5748647a84c2dd1b9df52995a6682ede98ec64265 +size 149995 diff --git a/msigdb_gocc/basic/plot_23.png b/msigdb_gocc/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..daefff1de7a54efe443185bb6cb18bf03d5d4505 --- /dev/null +++ b/msigdb_gocc/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:26628850419f6384d2094cfe5aeb3c12c22481757ece2e60dae16d3b0d7ca37e +size 141131 diff --git a/msigdb_gocc/basic/plot_24.png b/msigdb_gocc/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..9ff5300577d450ff319bc357c989b20ae9e5039c --- /dev/null +++ b/msigdb_gocc/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b5e5435d5d9d833e2c65cde2b33a68096b2336247586722da5e166626570047b +size 148785 diff --git a/msigdb_gocc/basic/plot_25.png b/msigdb_gocc/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..090b5b97f325e2032b602604ff3e7ea3beb773d7 --- /dev/null +++ b/msigdb_gocc/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dce41f15a8ad831592ca3e2213adea8beab8c7550c8e5d4b6d73c77c3616ad41 +size 139957 diff --git a/msigdb_gocc/basic/plot_26.png b/msigdb_gocc/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..e8df5044aed65a2bee57d293ef46250d487ab472 --- /dev/null +++ b/msigdb_gocc/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14f8d451d3ec6b048eb1fd6069dc6ad804ca9eba74ce6a4305596de849cc39a0 +size 150669 diff --git a/msigdb_gocc/basic/plot_27.png b/msigdb_gocc/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..ab7687416792f2dcc6ff06992e34eb2f0f128ca6 --- /dev/null +++ b/msigdb_gocc/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5b0a06d42ed00f0743c14af2c923ede548e0eec167a98bd74fa6641b0278d8a +size 148852 diff --git a/msigdb_gocc/basic/plot_28.png b/msigdb_gocc/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..03e772bd86f60cd67aa29be0ebe9eac4ca19611d --- /dev/null +++ b/msigdb_gocc/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c0df765bd922c55ab142bd06d1bd0cd90fde8c93d586597a0e158571f2487f3 +size 138407 diff --git a/msigdb_gocc/basic/plot_29.png b/msigdb_gocc/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..625b4fb7d59764fd3a4b4f10b68292ae98db44e1 --- /dev/null +++ b/msigdb_gocc/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72f280e19d0723fb9deae211953b1ad5e21a08f3eca9800494b5ca661ee38634 +size 145659 diff --git a/msigdb_gocc/basic/plot_3.png b/msigdb_gocc/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..b333f9d5d18e25fc933821fa85202b3b83408b9f --- /dev/null +++ b/msigdb_gocc/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a014538066963e6fcd259884f50f240dd92552189858529f7fe6cbaddc727e2 +size 139236 diff --git a/msigdb_gocc/basic/plot_30.png b/msigdb_gocc/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..1862865dd58ec842d40de0a4a8136c4153fba877 --- /dev/null +++ b/msigdb_gocc/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de56cf9ea1612e6280e4ddfd87541e011dd98a6254a08b1387508f7a15de2f65 +size 146112 diff --git a/msigdb_gocc/basic/plot_31.png b/msigdb_gocc/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..5af4e8000bfe138ec70a9ef7e2a4e4cbfe789a1d --- /dev/null +++ b/msigdb_gocc/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:93bb1cdf116118207faf9845b31e93d7654b2f70211fa901f96f6585e5d896d0 +size 140304 diff --git a/msigdb_gocc/basic/plot_32.png b/msigdb_gocc/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..6a321eb7a55aca61cf0dd0b8da1222da5fb5e880 --- /dev/null +++ b/msigdb_gocc/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f1abe58044c63a533ca0422a4add57d33e9a2993cb24012e2dc1524a217fd87d +size 143907 diff --git a/msigdb_gocc/basic/plot_33.png b/msigdb_gocc/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..fce97395e7daa6c926f86aad9ed685dc3b351379 --- /dev/null +++ b/msigdb_gocc/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6fe741208cddff4cd8b4fcd69bc4e8c018b642bbd29dd8b483a7f7ddac1a37c7 +size 136438 diff --git a/msigdb_gocc/basic/plot_34.png b/msigdb_gocc/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..98ade265fd4e7448bcb5c91f9c68d856737438e3 --- /dev/null +++ b/msigdb_gocc/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d657abdd7e169ac23b09b45b4fe48af747781bf3b20f4c73407f1516e04444e1 +size 141671 diff --git a/msigdb_gocc/basic/plot_35.png b/msigdb_gocc/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..e5b19981ba9a806b285184ef7933a771eab23381 --- /dev/null +++ b/msigdb_gocc/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4fd231651e85a0d65e178e10d0894ea12a03f7000ac53bb07dad50048017e77d +size 146046 diff --git a/msigdb_gocc/basic/plot_36.png b/msigdb_gocc/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..087e1a0f812f292c620205a344d88f3e3f6f1b6a --- /dev/null +++ b/msigdb_gocc/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2d3d64f17d98b7e5c8639926a18de0130f0a288e1e8b967b02d6bb94f2614554 +size 152313 diff --git a/msigdb_gocc/basic/plot_37.png b/msigdb_gocc/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..5f0566f95f8a187b259256e9589436208939866a --- /dev/null +++ b/msigdb_gocc/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:570c774f31930c83e6a76e80dfb210f8c91320670791c1682eb7e3cfe48361d6 +size 140882 diff --git a/msigdb_gocc/basic/plot_38.png b/msigdb_gocc/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..2ec452948fb72d4dd9a0d38895ac541c4e1d46bb --- /dev/null +++ b/msigdb_gocc/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:96c154cad242bf8771a0a245cddf7f8dbe610d0fd9cbeca1503c1bcf1ef782c4 +size 149268 diff --git a/msigdb_gocc/basic/plot_39.png b/msigdb_gocc/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..8da50ee20ed2027baa6a3ed75965429ba099995d --- /dev/null +++ b/msigdb_gocc/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6d0878d818726fd5f452b933356cd757506014e07fe051430f2f5b63171d031 +size 145626 diff --git a/msigdb_gocc/basic/plot_4.png b/msigdb_gocc/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..43534344789d8123a539ce5e162d81644060bc36 --- /dev/null +++ b/msigdb_gocc/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d5a3708321b78c56ec05fa2ca15cb274b13b2ca98d6c0156ad51ea2fa2283a4 +size 138570 diff --git a/msigdb_gocc/basic/plot_40.png b/msigdb_gocc/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..38cf813aff1585d3096d544e593257578c1c398c --- /dev/null +++ b/msigdb_gocc/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7370d9a1007ca8353d171e185aa4620f7e005a6392af5d0275894ef7a4f77af7 +size 146702 diff --git a/msigdb_gocc/basic/plot_41.png b/msigdb_gocc/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..ad0380981ce61e7369f265572b0d67226cac46fb --- /dev/null +++ b/msigdb_gocc/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5a498e9ad0aa600f2fc40c35269dc77e8b0d4c96bc6f37e3032b32e969282e6 +size 143281 diff --git a/msigdb_gocc/basic/plot_42.png b/msigdb_gocc/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..aa6a3d6697e8926e2bae41b67778f88e108a6f12 --- /dev/null +++ b/msigdb_gocc/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bbf36d9e1deaffd57694c60fa52b51d9f51a13ed54d7dfd727cb676c7a2d0c6b +size 138515 diff --git a/msigdb_gocc/basic/plot_43.png b/msigdb_gocc/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..78cbe76bc0115df7bb3d024dc703c5a762c00986 --- /dev/null +++ b/msigdb_gocc/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:382795b62d9ef541c3c6c5d5ab5c0a05d16d9a895395b59310302ac4b60c2074 +size 141697 diff --git a/msigdb_gocc/basic/plot_44.png b/msigdb_gocc/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..57281aa451958640bb4571304fdb01a447c4398a --- /dev/null +++ b/msigdb_gocc/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:37ab34d93c81c7e8cbb41b8b66d82fa6bfaa9551253fbc6bfddb3036ffe09a1a +size 144352 diff --git a/msigdb_gocc/basic/plot_45.png b/msigdb_gocc/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..7a3f78524b44af690c47a2d1e95ebabd2ac8f514 --- /dev/null +++ b/msigdb_gocc/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:75f201064be80118ce9f3727729c361221bece81fd7fb6e649f3a13c00eb524d +size 149037 diff --git a/msigdb_gocc/basic/plot_46.png b/msigdb_gocc/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..f537a93832fa0085f48b8b295b8d6c9091140d97 --- /dev/null +++ b/msigdb_gocc/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f2f76fbaf8941c269decdcccd4735f56f6c31273b68ed863a1acd0b856dbf53 +size 142838 diff --git a/msigdb_gocc/basic/plot_47.png b/msigdb_gocc/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..3853b157be1e73ad885f226ec0affec49ca614b2 --- /dev/null +++ b/msigdb_gocc/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f82a286d6c57bd9f3527e74e3cd8f8e6f669b5ebce641114b53902ac0d865b2 +size 141584 diff --git a/msigdb_gocc/basic/plot_48.png b/msigdb_gocc/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..265c28721f833eb65403c9df7793c0e42f92cfcd --- /dev/null +++ b/msigdb_gocc/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6eb1045c736923cf49b02b61ea576f368ac1eba15644091380a9b47df1c5414 +size 140638 diff --git a/msigdb_gocc/basic/plot_49.png b/msigdb_gocc/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..2e4301aadebcf10c79e71928c13486f6a3f1294c --- /dev/null +++ b/msigdb_gocc/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:254b312b86078c71adc6cb33d68d786f4de2f3fdbadfbe9a2c4a8f3370a44dbe +size 145220 diff --git a/msigdb_gocc/basic/plot_5.png b/msigdb_gocc/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..19ae3306c3269ddeb6e08349b62423626e91973a --- /dev/null +++ b/msigdb_gocc/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb4f18bbe6f919bb627b9adf795d8c74125fc7ab073bf253ba3c585699714ffa +size 148634 diff --git a/msigdb_gocc/basic/plot_6.png b/msigdb_gocc/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..632cec64cf0223cf32c47b17cfd049a3b1245224 --- /dev/null +++ b/msigdb_gocc/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6e5faf65828f5bf06e22b369551d5eff1b01f0a68d20bcd185a7666678fde3bb +size 140346 diff --git a/msigdb_gocc/basic/plot_7.png b/msigdb_gocc/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e78e03587a433ef3e7348941c96be3facd4043fb --- /dev/null +++ b/msigdb_gocc/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c01dc3160a218aa4ccb498c9e513a8cc04140661214da9de7abfa34b6cc0b7d4 +size 145625 diff --git a/msigdb_gocc/basic/plot_8.png b/msigdb_gocc/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..1c4d6efe61b4f8732ae78bd2d5d35ad32cce3ba3 --- /dev/null +++ b/msigdb_gocc/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c968f2e8db9ff179a0cb03b9743fb0f7438584fda3362d95218a9f01a4706b3d +size 139519 diff --git a/msigdb_gocc/basic/plot_9.png b/msigdb_gocc/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..2e5b057e1a44a1a9de4f38b75bb1668d3c5e1549 --- /dev/null +++ b/msigdb_gocc/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3284b46a9b2e2493641ccf419412e9f86a2eabf6ca71cb8c408ed25a1e56030 +size 138893 diff --git a/msigdb_gocc/consensus.joblib b/msigdb_gocc/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..46834e5c0858ce7ddb4626d6c520b0b4021f0061 --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fdb42df52d75d305b08bc3e678f5595059be07e2b6c17fc012a5570763e0e144 +size 186528 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e4b7e0821aff17f82ae6379767b6c27c78800a7c --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,94 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Organelle inner membrane 118 258 6.929060202448982 4.236455035489546e-12 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 2.0822439501487358e-32 7.18909174359896e-07 4.8858215753962013e-14 1.4398971438788332e-19 6.473585482190572e-32 +Nuclear outer membrane endoplasmic reticulum membrane network 166 338 6.91792543018562 4.583054098069741e-12 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 4.484909014427956e-30 0.0006101078222898 7.472656039321343e-06 1.1016325773664804e-21 2.1749779587957303e-31 +Organelle subcompartment 209 421 6.908521413554501 4.89731075715129e-12 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 2.9209263809296882e-33 0.001466371855613 3.664194850294712e-05 5.548478388449584e-22 2.165270194615533e-34 +Mitochondrial envelope 147 341 6.263519483214799 3.763841035893615e-10 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 1.4928853767170655e-38 2.2204547547940797e-11 1.954717383072584e-15 4.686393817639394e-25 1.2277367558904731e-38 +Endoplasmic reticulum 244 532 6.251619237517762 4.062187849805868e-10 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 1.2991957851867757e-33 0.0031895953463959 1.6781114718033577e-07 8.77810854405732e-25 1.4948595755522863e-34 +Intrinsic component of organelle membrane 104 151 6.1422665136750405 8.13522089619046e-10 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 6.151056758222924e-25 0.1681111786366242 0.0083073369666447 4.0207799494860434e-14 2.276972801106723e-25 +Vacuole 102 245 5.269425343369197 1.3685151632585612e-07 55.029126213592235 212.35679611650485 0.7895788564169173 0.4204713883128338 16.092847298969616 21.031446114270427 2.221429361906059 0.4148180554719883 3.003624179055553e-12 0.0483365109534619 0.0028840435520208 2.228993885000858e-06 6.560943287427509e-13 +Golgi apparatus 158 372 5.212848659385651 1.859626050798384e-07 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 1.0071679508494728e-13 0.1944846062788499 0.2642548670658012 6.44143565400506e-07 3.9431554022384894e-14 +Envelope 223 520 5.205827998136182 1.9313347790747322e-07 133.55825242718447 476.99271844660194 1.1125762168925015 0.4931727688685032 47.82674034566458 40.415168802184624 2.6300132137901633 0.4489464989697134 1.7293863970160733e-35 5.65377522753309e-09 1.9980416251633933e-15 3.802028082487609e-22 5.485473994071855e-36 +Golgi membrane 85 151 5.140842539184985 2.7350920002099697e-07 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 3.1475211201547097e-10 0.1386663086468896 0.2243679728517654 4.169767941653207e-07 1.7429168887891364e-10 +Membrane protein complex 127 319 4.844568604510507 1.2688706984090757e-06 80.6747572815534 286.40291262135923 0.8072324880333213 0.5482017098759524 27.14508025817277 25.65052264389531 1.8803092756171496 0.4277745875695662 9.419874071809857e-16 8.423078084060036e-06 1.0965487027245315e-06 8.905250232436827e-09 6.99169590651518e-16 +Lysosomal lumen 23 36 4.841203990339773 1.2905480768488076e-06 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 2.6484454708744384e-15 0.0002823024527817 2.509638720091066e-07 5.371265448406509e-11 3.643541562748924e-15 +Endoplasmic reticulum golgi intermediate compartment membrane 22 30 4.215331507600301 2.494115461804114e-05 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 2.0083092376581397e-07 0.0275080115441885 0.0978881295505725 0.0020419820824666 2.390856538257985e-07 +Intrinsic component of mitochondrial membrane 45 54 4.190796884382639 2.779764253557637e-05 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 1.284791561184506e-14 0.0060275441501108 0.0001066840361729 2.8492680031730624e-06 1.7816851189935175e-14 +Intrinsic component of endoplasmic reticulum membrane 41 60 4.109690508357496 3.9618974799315865e-05 21.439320388349515 53.03155339805825 1.5445183869163015 0.2945609219212759 9.936629672422429 6.151523176643304 2.1054078800196185 0.3580268322643601 5.177833074829124e-09 1.0 0.3421855883923391 2.0451748774925363e-06 1.356844418415236e-09 +Intrinsic component of mitochondrial inner membrane 31 35 4.102673231466476 4.084038602125695e-05 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 6.466713846569255e-11 0.0016433207319124 0.0001113664394611 2.3584197917317812e-05 8.084672558338859e-11 +Azurophil granule membrane 13 24 3.915831125866022 9.009329705955692e-05 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 1.6486603488182724e-08 1.0 0.0096938597365547 0.0048857385669874 1.97441963311593e-08 +Vesicle membrane 105 298 3.8696940220776974 0.0001089720300635 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 9.951996017923677e-08 0.2942047087187876 0.2031418080328079 0.0034053171171262 3.6211605565917486e-08 +Mitochondrial protein containing complex 55 161 3.827423959493621 0.0001294913688594 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 4.86299501463584e-18 2.2745072988397365e-07 2.223087163357044e-09 4.85193412739161e-10 8.886591614473377e-18 +Vacuolar membrane 65 145 3.6755469645413408 0.0002373403726809 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 1.0338841976946748e-08 0.4743293946875169 0.043321771829639 0.0005410123966426 5.115412256887092e-09 +Trans golgi network membrane 16 33 3.65428380785988 0.0002579008683611 7.097087378640777 25.808252427184467 0.4300178223009387 0.4839581535123586 3.4857952056404495 4.861642003007495 1.0577526504941306 0.3235584371830635 0.0001083252985717 0.2821140734917597 0.4925597827158772 0.0068401475593005 0.0001239395608574 +Endosome 88 256 3.641273028685161 0.0002712932392929 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 0.0001903067400685 0.6356511738983688 0.4917919823223609 0.0152060652941446 0.0001490277196838 +Intrinsic component of plasma membrane 59 96 3.639629399935276 0.0002730307079055 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.0056789279497567 0.8952079263444598 0.8330259814094686 0.1024361120998917 0.0012264104944042 +Outer membrane 51 99 3.553473900980481 0.0003801789186526 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 1.7558628917898993e-13 0.0001903287561044 0.0003409613770365 4.0144711489803103e-10 5.0466316312883584e-14 +Inner mitochondrial membrane protein complex 34 81 3.542439694145115 0.000396444058424 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 3.909353758079131e-18 1.5573892950981242e-07 3.334399208219031e-10 3.605725425690355e-10 6.213965328197463e-18 +Respirasome 16 45 3.295342429437099 0.0009830181462189 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 4.398572159324601e-07 0.0073818564025025 1.429145151632323e-06 1.1325122383507624e-07 5.37153859631512e-07 +Endoplasmic reticulum golgi intermediate compartment 26 55 3.2768882324190733 0.001049579078403 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 3.530021481893602e-06 0.0108939889612075 0.0681614338573012 0.0096006639064149 4.273780721365706e-06 +Copii coated er to golgi transport vesicle 16 37 3.2328370152630472 0.0012256746889725 10.810679611650484 32.4247572815534 0.9209697551014924 0.3949407296339237 5.01338814607213 3.9617918728777735 1.2509556054930144 0.3456813773327062 0.000309169259787 1.0 1.0 0.4855818636226243 0.0003492096622138 +Vacuolar lumen 27 67 3.2094579935443237 0.0013298547675257 22.262135922330096 63.33980582524272 0.6562244405592584 0.1887666227175413 6.920437110961116 4.902057024259538 2.8947011026985514 0.298290072492813 2.1430144482376048e-11 0.0020388417604097 1.3871254672632278e-05 1.5300130495723574e-08 4.702904303179454e-12 +Secretory granule membrane 38 81 3.1652846557241494 0.0015493129791719 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 1.2970266526119752e-07 0.577581418089764 0.0965212586027388 0.0045446840158695 1.7296558384545218e-07 +Outer mitochondrial membrane protein complex 11 16 3.153224259901236 0.001614777020316 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 7.040182931388264e-09 0.0039064712270754 0.0155240337321844 0.0011993766429203 8.073414733415837e-09 +Golgi cisterna 15 28 3.150206273072328 0.0016315522395569 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 0.0078837718793126 1.0 1.0 0.2599162900657007 0.008617935758856 +Endocytic vesicle membrane 23 47 3.1198517070167195 0.0018094210738428 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 0.007824389829402 1.0 0.6662735487440652 0.2930898711130077 0.0087148542276409 +Snare complex 11 19 3.088160187289742 0.0020139987833975 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 0.0008683313042841 1.0 0.3404254693467198 0.0198035379531722 0.0009526402681126 +Cytochrome complex 5 17 3.0822843657464603 0.0020541849901198 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0003471406336639 0.0081256981844374 0.0001585002786519 5.657491778833551e-05 0.000378511976274 +Endoplasmic reticulum tubular network 9 15 3.07647912898773 0.0020946096610088 4.456310679611651 11.402912621359222 0.7597390036291544 0.4204688348420043 2.5600618129260964 1.9933849978482647 1.110800197793671 0.3406591463359876 5.0814428209822654e-05 1.0 1.0 0.0017432511761074 5.564378317152988e-05 +Proton transporting two sector atpase complex 11 26 3.037828833469181 0.0023828926263667 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 2.7189135598155166e-06 0.0005288989187626 0.0041517217414646 0.0012549484261259 3.0899315726376227e-06 +Cis golgi network 13 19 3.013186468470938 0.0025852001751902 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 7.280030543057949e-05 0.1683799151698467 0.0538434207197609 0.0142235096743441 8.125377290359248e-05 +Organelle membrane contact site 12 19 2.989293363500143 0.0027962351315085 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 0.024572842909207 1.0 1.0 0.2076979954646016 0.0062617463102783 +Nuclear envelope 60 185 2.8986280994375693 0.0037479916935585 37.96116504854369 174.33252427184465 0.0181336977438782 0.7301070934005458 14.47490116343478 13.385385830159189 0.8830829676796945 0.3416784661439265 0.0069526769480772 0.8335602713867643 0.0268830935747168 0.1200803657516335 0.0046180216181192 +Transport vesicle membrane 20 49 2.828087470341057 0.004682700995789 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 0.0088693838417176 1.0 1.0 0.8241642951505768 0.0039580527577536 +External side of plasma membrane 17 28 2.7684806027606146 0.0056318337968663 6.856796116504855 22.03640776699029 0.7617836494895279 0.3205100812766187 3.0547396608098576 3.343757364022431 1.3549821177336052 0.303342613906597 0.5796404541732101 0.395163544863046 0.6426690076912178 0.4759621819475993 0.4122401222672924 +Exocytic vesicle 21 42 2.7616684562552374 0.005750684186081 12.106796116504857 38.40533980582524 0.7408080162244459 0.4227017753873355 4.952517495270036 4.6543925000719675 1.3317240485888555 0.365166844745196 0.0300788234677545 0.4758931785581557 0.7334832776882521 0.6444243223266553 0.00633413601384 +Nuclear inner membrane 12 22 2.7611445705117825 0.0057599173277897 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 0.0007371572108087 1.0 0.0075361578498098 0.0032788281256578 0.0008092232876479 +Specific granule membrane 7 18 2.7596082712086214 0.0057870707221077 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.0287482913537027 0.2068720246493716 0.0803922289273931 0.006410021202963 0.0305407497227627 +Apical plasma membrane 33 50 2.752829831837891 0.0059082597717041 13.313106796116504 44.91504854368932 0.8056122914935105 0.4638533528605782 6.08368206230376 5.803837594461636 1.1490032654706197 0.3657186109722784 0.2270637432307133 1.0 0.7851702278936415 0.7413556681522777 0.1472426911854084 +Phagocytic vesicle membrane 14 27 2.740607527310365 0.0061325712089217 7.512135922330097 23.83009708737864 0.5348434256443761 0.4468744105904624 3.681144332021715 3.0024693704800938 1.1652764437248655 0.3385441964418395 0.0260303627734288 1.0 1.0 1.0 0.0278547210480151 +Basolateral plasma membrane 24 46 2.695109380541979 0.0070365527946407 11.907766990291265 41.713592233009706 0.4173504135492652 0.5464661760255546 5.696723454799589 5.533263026209871 1.098008793343998 0.3512755123780914 0.1005014632475626 1.0 0.6727295364723632 0.530532682082201 0.1072650551749109 +Organelle envelope lumen 21 40 2.68762265696052 0.0071962667197591 11.436893203883496 36.55339805825243 0.6276066761486734 0.4428242266058088 4.702137301503097 3.7796803567009714 1.1382138566471218 0.3469405856623805 4.159674824076535e-06 1.0 0.5351022899588459 0.0121231126733016 4.9483484464243714e-06 +Intrinsic component of mitochondrial outer membrane 9 15 2.6774114988135955 0.0074193450498569 5.004854368932039 12.186893203883496 0.537559322132711 0.4142348023165385 2.5976045215999015 2.144426747635188 1.2224430201503769 0.3320793466689031 0.0040771188388817 1.0 0.1993869387044997 0.1060727287920157 0.0043329575683166 +Synaptic vesicle membrane 9 17 2.673383105083445 0.007509044123948 5.099514563106796 14.07766990291262 0.7734258277348643 0.4227625879426745 2.579286376297321 2.2325453295101236 1.0485572818049853 0.3297289695807819 0.1674258684290813 1.0 1.0 0.4371334046337463 0.0750518175373725 +Transport vesicle 45 105 2.669180595086722 0.00760365543587 26.046116504854368 92.34708737864078 0.9512017428916244 0.4458616213657612 9.46815354334768 9.09007867686459 1.424803887648301 0.3967491654773343 2.0336342580213305e-05 0.348957119320241 0.2423406323390604 0.2989758563376967 3.5516019535396127e-06 +Intrinsic component of synaptic vesicle membrane 6 12 2.636399842709174 0.0083790932280305 3.648058252427184 9.116504854368932 0.724313202500786 0.4129003553732678 2.1933086936710184 1.7154408466980504 1.018214829869002 0.3297596143558817 0.0382192701106142 1.0 1.0 0.1383652025719425 0.0399552443236748 +Microbody membrane 13 33 2.622253157788679 0.0087350518977986 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.001435349653862 0.236404668572991 0.4242240140575919 0.0120464435451714 0.001584251501391 +Tim23 mitochondrial import inner membrane translocase complex 3 7 2.618950230506808 0.0088200814699936 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0013168186836578 0.0011617774889038 0.0001343549216781 0.0020064706347618 0.00138858926748 +Golgi apparatus subcompartment 48 109 2.5855806087434363 0.0097215138136386 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 4.703038941517671e-05 0.7290395724580129 0.7428710491917419 0.0338306149356432 6.074474961443712e-05 +Golgi associated vesicle membrane 5 23 2.571902406616573 0.0101141398384503 4.201456310679611 19.589805825242717 0.79417597045559 0.3511132904952779 2.457541951272857 2.384047500904294 1.2111660039755976 0.3110721945776767 0.0113061233293034 0.0151070197534971 0.0065760397653667 0.0155108289838298 0.0120719478590556 +Intrinsic component of golgi membrane 9 11 2.526852848040758 0.0115089713434 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0142602893676462 1.0 1.0 0.0032788281256578 0.0152089373127818 +Integral component of synaptic vesicle membrane 5 7 2.5178536374251665 0.0118072374145077 2.2475728155339807 4.910194174757281 0.8567274645780141 0.3149754325120096 1.3818760752746044 1.4445051429216968 1.1133243513780926 0.2989777184888048 0.0075518132359909 1.0 1.0 0.062605312422627 0.0079370796506279 +Azurophil granule 30 72 2.514099847171304 0.0119336642336269 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 1.2957845655873336e-10 0.4205819691215787 0.0049403667773054 0.0004653137266356 2.944433176928635e-11 +Endoplasmic reticulum protein containing complex 35 67 2.510597832321768 0.0120526919966488 20.067961165048544 61.213592233009706 0.544324442160867 0.4875881372361492 7.672624563199495 5.300944201362535 1.5348103009085623 0.3893079894443684 3.316135569202917e-06 0.4009047789919011 0.2783549011870566 0.0012066818666679 4.048942520430883e-06 +Er ubiquitin ligase complex 5 8 2.486997946436801 0.012882614265725 2.0970873786407767 4.70873786407767 0.8764155338390741 0.2924583478733635 1.3110031963021629 1.3573322490080977 1.246637632205364 0.2924172085124771 5.1265180635653765e-05 1.0 1.0 6.292953854873037e-05 5.489393781591606e-05 +Endoplasmic reticulum lumen 46 69 2.475606728122068 0.0133010000342657 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 0.0030546256816524 1.0 0.0796420088853105 0.0217407735244723 0.0014398235587049 +Golgi stack 17 37 2.4608972759659378 0.0138590040461026 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 0.045124366656777 1.0 1.0 0.4251492251315837 0.0486153614380544 +Proton transporting two sector atpase complex proton transporting domain 6 12 2.4453409198864464 0.0144715274628892 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 4.07724887077838e-05 0.0021914548918381 0.0088504827764808 0.0051503840765812 4.417853810010275e-05 +Respiratory chain complex iii 1 8 2.3879780857826733 0.016941351932439 2.5145631067961167 7.186893203883495 0.8648567981956616 0.2640480169416735 1.5224155414895728 0.9433070612984726 1.3007640218760226 0.2795290338624424 0.1263621008341029 0.0016377422378922 0.0066572828402184 0.0382400085743442 0.129364196063302 +Golgi associated vesicle 9 36 2.381311629435215 0.0172511112164213 6.745145631067961 30.33009708737864 0.696501539533066 0.3869218626415568 3.3093865809086713 3.3403631844705557 1.2881306559419168 0.3350067162782171 0.0013936948333769 0.0406061543885706 0.0040840095186766 0.0242455864981032 0.0015503267588381 +Micos complex 4 5 2.372094990314918 0.0176875427540232 2.4927184466019416 4.725728155339806 0.7557668283408772 0.3464970141803932 1.2077602589329477 0.4877312285913208 1.1862461875397572 0.3249829583805667 1.2346577053130028e-05 1.0 1.0 0.1781979724676324 1.3236156489067347e-05 +Autophagosome membrane 8 14 2.35756847109278 0.018395062570323 4.174757281553398 13.37135922330097 -0.0098942360451326 0.445924723627937 2.326200220393679 3.0901432865083773 1.1383635180898088 0.3067757682348186 0.1586651765418901 1.0 1.0 1.0 0.1644709145443467 +Late endosome membrane 19 44 2.340210349994964 0.0192728815303206 8.400485436893204 35.220873786407765 -0.1907871949509251 0.3412955054288843 4.360825137615114 6.285848739997517 1.5677242851178623 0.3272837423268039 0.0055974107221302 0.4396258949303272 0.6943670866160305 0.1740979244634158 0.0023639052461662 +Mib complex 7 10 2.285220364610067 0.0222999096801912 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 1.5180285244009463e-05 1.0 1.0 0.0382400085743442 1.6468344784532795e-05 +Lumenal side of membrane 7 11 2.282081332076765 0.0224845389191368 3.686893203883495 9.509708737864075 0.6270696996832885 0.3351332813726532 1.8490414883089543 0.9791034697552432 1.2332692274886168 0.3003490996154719 0.0192115706028201 1.0 0.191600110602388 0.0983610682747182 0.0035298468720628 +Golgi lumen 3 6 2.266598006205363 0.0234147940052023 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.0650574840344539 1.0 1.0 0.0415700360883472 0.0678374957909117 +Respiratory chain complex iv 6 10 2.216212227618544 0.0266769708444558 3.754854368932039 9.74271844660194 0.8119042784517004 0.2590637228606872 2.032646352020888 1.0643473720992946 1.3870085883810457 0.2875864020654643 0.0093478027703867 1.0 0.0126574737404708 0.0087554356838108 0.0098193480789534 +Proton transporting atp synthase complex 5 13 2.202559246316639 0.0276258289929451 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 9.285534997667568e-05 0.0028214739728005 0.0113213926532688 0.0074273483269255 0.0001004910149917 +Late endosome 33 81 2.199813458649684 0.0278201326999483 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 0.0008300977206885 0.6236348561305805 0.5898982141989131 0.027505029729526 0.0004021171615841 +Secretory vesicle 87 284 2.1963295722146388 0.0280683625503026 56.25485436893204 257.47087378640776 0.1341228551105892 0.6386901443364594 16.601865631745117 19.12774191814033 1.3029114519128766 0.3900514633935764 1.760820491569901e-08 0.1319443674160473 0.1006875457402453 0.0032328177020604 1.8352909671855481e-09 +Golgi cisterna membrane 9 21 2.188408987180675 0.0286398242238736 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.0371575218425068 1.0 1.0 0.3601862036851755 0.039409055534926 +Pore complex 4 8 2.169056367258017 0.0300784047525943 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0009513571658216 1.0 0.1515272625734178 0.00062382482254 0.0010145405611514 +Er to golgi transport vesicle membrane 8 24 2.157111805124774 0.030996954015602 6.495145631067961 21.890776699029125 0.3958870084748403 0.5141628679854253 3.1618901389258056 2.1225127942575894 0.9657155478739712 0.3164691847513972 0.004578910583524 1.0 1.0 1.0 0.0049481295197396 +Lumenal side of endoplasmic reticulum membrane 6 8 2.136888556116196 0.0326070570149559 3.0776699029126213 7.361650485436893 0.5475818769285827 0.3637002691484017 1.5990854205757892 0.8689828861838115 1.1522443815379428 0.2937666584254462 0.0523318189589597 1.0 1.0 0.357118555081159 0.0098193480789534 +Copi coated vesicle membrane 3 13 2.130347453665622 0.0331429385315555 2.9611650485436893 12.451456310679612 0.9351146201256926 0.2894293018559171 1.7580457491925867 1.2208038158644114 1.2401568068418547 0.2855671555488221 0.0059987647490075 0.0024970154667983 0.000440337804097 0.0062267265321947 0.00630824692371 +Intrinsic component of nuclear inner membrane 4 7 2.105706934530941 0.0352298171023186 2.4344660194174756 6.461165048543689 0.7221555748366164 0.3746407047127702 1.5973511010756076 0.8763043548183138 1.0289148549650529 0.2984963891905157 0.0410608346473262 1.0 1.0 0.1577810442013011 0.042147958906207 +Hrd1p ubiquitin ligase erad l complex 3 6 2.0826265833163866 0.0372852741703635 1.5922330097087378 3.79126213592233 0.7277489081729471 0.3220832800800837 1.0445131090737272 0.9111612984907131 1.2162191074948896 0.2849748010669527 0.0001629337315557 1.0 1.0 0.0004573905935078 0.0001722011086768 +Copi coated vesicle 4 14 2.075920607459051 0.0379012944343968 3.366504854368932 13.565533980582524 0.927757948703832 0.3021632050419245 1.9356503178232003 1.3008870969982682 1.2180478421179144 0.2957691490409697 0.0021155878345267 0.0039064712270754 0.0008717411361388 0.01180448121602 0.002252196025852 +Basal part of cell 25 55 2.02855390816324 0.0425037472558742 12.87378640776699 49.39563106796116 0.4231791430151931 0.5418083225496748 6.317535484281435 5.887808725837185 1.1575518486276402 0.3620095959132046 0.1350141404350939 1.0 0.7437191583737877 0.6637742722087006 0.1440597205041469 +Presynaptic active zone 8 17 2.0225068910788644 0.0431240124136023 4.803398058252427 14.970873786407768 0.3940654670567658 0.5114928405011878 2.7795522630987173 1.9568466345271975 0.9528581059832693 0.3105803383532612 0.419627612916546 1.0 1.0 1.0 0.2142435661583282 +Proton transporting atp synthase complex coupling factor f o 3 8 2.0062607186555703 0.0448284386827706 2.388349514563106 6.79126213592233 0.5842994650422648 0.284211882186535 1.5103719705721683 0.8950355849210965 1.3255228108854136 0.2674401609228611 0.0008708072207696 0.0009534063593398 0.0039135152062846 0.001485709034831 0.000918782674844 +Pigment granule 26 64 2.004094979475453 0.0450598871255558 17.058252427184467 60.37135922330097 0.3452760243889364 0.5728855837677844 7.454164461546019 2.3255555964379067 1.200064167427868 0.3798846852248331 0.0107604554963987 1.0 0.5823300890010559 0.3727622753153998 0.0013210167473874 +Multivesicular body membrane 7 9 1.9944430920981089 0.0461036532247354 2.2597087378640777 5.703883495145631 -0.0909344370751552 0.5093211865371587 1.6289337487708992 2.277940746525038 1.0118959680768935 0.3083397222188037 0.6775027830598979 1.0 1.0 1.0 0.682815470497098 +Mitochondrion 189 667 1.9871827502456336 0.046902148704033 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 1.1558306465760753e-22 2.9052633723727192e-08 2.322652588033907e-09 1.5935953926768078e-12 1.7715684565926705e-22 +Lipid droplet 14 35 1.981702814716468 0.0475125120079973 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0131702034083795 1.0 0.4724360815693985 0.0216033331890521 0.0142520132559401 +Secretory granule 75 256 1.9638256456674128 0.0495503149276235 49.29854368932039 231.6504854368932 0.0742534337219474 0.6450440279734955 14.609170474630965 16.529443419678444 1.2643241567239918 0.3828342632667716 5.8506531968780594e-08 0.1884631060971134 0.0901689388506787 0.0030255707463636 1.3768800112240212e-08 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a6396b7826c07aa507e48f4fbf1e974e7534cf76 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 914, + "title": "Average number of proteins per term", + "value": 31.38621444201313 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..26c176ea10f92a975e4c032ad90ac15a5e40d28c --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..372cc5fdbc8e8a329701ada3300fa7e8f9c588cb --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,361 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organelle inner membrane 0.5747966164290567 6.929060202448982 4.236455035489546e-12 3.872120808948987e-09 1.4920476486787594e-09 258 Q9Y2R0,Q9UDW1,O75880,O60830,O14949,Q6PI78,Q9UDX5,Q99595,O75027,P00846,Q5JTV8,Q8NBN7,O43676,Q96TA2,Q9Y6C9,Q5SNT2,Q69YU5,O75964,Q9Y584,Q9H2D1,Q9BRJ2,O14925,Q16134,P22830,Q9H1E5,Q96CU9,Q99623,P03886,Q8WWC4,Q13423,Q8IXM6,P13073,Q9UBX3,Q9UG56,Q9UJZ1,P14406,Q9H061,Q9NVH1,Q9H2V7,Q9Y512,O75844,Q9BSK2,Q70HW3,P20700,Q9P0J0,Q7KZN9,P24539,P23786,Q96IX5,Q9Y6N1,Q86Y39,Q15070,Q5XKP0,Q96E52,Q9H2W6,Q13505,P15954,P00403,Q9Y5J9,Q9H9B4,O75746,Q6DKK2,Q96GC5,Q9BTV4,Q96D53,O60313,Q567V2,Q9Y6M9,P53701,P51970,O95674,O60220,P12235,Q9Y619,P20674,Q99720,Q14739,Q9BUR5,Q16891,Q8N8Q8,Q9NVI7,Q9Y5J6,O95139,Q8IYU8,Q7Z7H8,P12236,Q6UXV4,Q9NPL8,O43615,O95202,Q9H3K2,O75208,P50402,Q9NX63,Q9BUB7,Q9H300,Q9BQT8,O96000,P56378,Q5HYK3,Q9UH99,Q5T9A4,Q9BPX6,P56385,O14548,Q53H12,P21912,Q9Y5L4,Q6UX07,Q13084,P06576,P05141,Q9HC21,Q6NUK1,Q03252,Q10713,Q9NWR8,Q9NRA0 118 +Nuclear outer membrane endoplasmic reticulum membrane network 0.5831555121176661 6.91792543018562 4.583054098069741e-12 4.188912350871848e-09 1.4920476486787594e-09 338 Q9BQE5,P43307,P24390,P09601,P49458,Q8NHH9,P67812,O75787,O14678,P46977,P30519,Q9H490,Q4ZIN3,Q70UQ0,Q8N511,P37268,O95197,Q9Y4P3,P51648,Q9H3N1,Q15005,Q15006,O60725,Q9P2W9,Q86UE4,Q86YN1,P62942,Q92604,P26885,Q07065,O43731,P49257,Q15800,Q9Y3A6,O75844,O14735,Q5JRA6,Q86XL3,Q13438,Q8N0U8,Q9Y5M8,O95070,P01889,Q9BRR6,Q14108,Q9UBV2,Q9NUQ2,P35613,A1L0T0,O95772,Q8WXH0,Q99640,Q96PC5,P33897,P61026,Q96G23,Q12907,O00264,Q969X5,Q8N4V1,Q15629,Q9NP58,Q9NZ01,Q9NZ08,Q96CS3,Q9NQC3,P61019,O00400,P51572,Q15392,P52292,Q9H2C2,Q5T9L3,Q9H0U4,O95470,Q6NUK4,Q8TB61,Q96A33,Q92643,Q5BJF2,Q9BUN8,P07099,Q5VV42,Q9UKU0,Q8IV08,Q9HD20,Q9NTJ5,Q96RL7,Q8N5M9,O14681,Q8TCT8,Q969V3,O95674,A0FGR8,Q9Y6I9,Q16850,Q9GZP9,Q86UP2,Q96HY6,Q9Y282,Q13586,Q10472,Q99720,Q9NPA0,Q969M3,P04844,Q15904,Q96KC8,Q14739,Q9BUR5,Q6NTF9,O43852,O60427,Q8TCT9,Q99735,Q06136,Q96RQ1,Q15363,Q14849,O76024,P38435,O15260,Q9BRK0,Q8NF37,Q14534,O43292,Q03518,Q86TM6,P27544,P50402,P51571,Q12981,Q15125,Q9BT22,Q96N66,P16435,Q8N2F6,Q5H8A4,Q96JJ7,Q9H6H4,O15269,Q96AA3,Q8TD16,O14653,Q8WVM8,P04439,Q8N5B7,Q9P035,P10321,Q6NUQ4,Q96RD7,P16615,O75845,P49755,P04035,Q9NP80,P42345,Q7Z2K6,Q13190,Q53GQ0,O00429,O00560,P27824,Q9Y320,Q9UBU6,Q96S66 166 +Organelle subcompartment 0.5845017775610355 6.908521413554501 4.89731075715129e-12 4.4761429360293115e-09 1.4920476486787594e-09 421 Q9BQE5,P43307,P24390,P09601,P49458,Q8NHH9,P67812,O75787,O14678,P46977,P30519,Q9H490,Q4ZIN3,Q9HC07,Q70UQ0,Q8N511,P37268,O95197,Q9BXS5,Q9Y4P3,P51648,Q9H3N1,Q15005,Q15006,Q96CN9,O60725,Q9P2W9,Q86UE4,Q86YN1,P62942,P15291,Q5VYK3,Q92604,Q8NBN3,P26885,Q07065,O43731,P49257,Q15800,Q9Y3A6,O75844,O43493,Q8WTW3,O14735,Q12846,O00461,O43752,Q13438,Q8N0U8,Q5JRA6,Q9Y5M8,Q86XL3,O95070,P01889,P40616,Q9BRR6,Q14108,Q00765,Q9UBV2,O15127,Q9NUQ2,P35613,A1L0T0,O95772,Q8WXH0,Q99640,Q96PC5,P33897,Q9BZG1,Q96G23,P61026,Q12907,Q9H4A6,O00264,Q969X5,Q8N4V1,Q15629,Q13637,Q9NP58,Q9NZ01,Q9NZ08,Q96CS3,Q9NQC3,P61019,Q16706,O00400,P51572,Q15392,P52292,Q9H2C2,Q5T9L3,Q9H0U4,O95470,Q6NUK4,Q8TB61,Q96A33,P04062,Q92643,Q5BJF2,Q9BUN8,O60499,P07099,Q8N2H4,Q5VV42,Q9UKU0,Q8IV08,Q9HD20,Q9NX62,O95249,Q9NTJ5,Q96RL7,Q8N5M9,P11717,O14681,Q8TCT8,Q969V3,O95674,A0FGR8,Q9Y6I9,Q16850,Q9GZP9,Q86UP2,Q96HY6,Q9Y282,Q13586,Q10472,Q04656,Q99720,Q9NPA0,Q96JH7,Q969M3,P04844,Q15904,Q96KC8,Q14739,Q9BUR5,Q6NTF9,O43852,O60427,Q8TCT9,Q99735,Q8N1B4,Q06136,Q8TEM1,P50570,Q96RQ1,Q14789,P04843,Q15363,Q14849,O76024,P05067,P38435,O15260,Q9BRK0,Q8NF37,Q14534,O43292,Q03518,Q86TM6,Q9UID3,P27544,P50402,P51571,Q96A57,Q12981,Q15125,Q9BT22,Q7Z6M1,Q96N66,P16435,Q8N2F6,Q5H8A4,Q96JJ7,Q9BSR8,Q96ED9,Q9H6H4,O15269,Q96AA3,Q9NPR9,O14653,Q8WVM8,P04439,Q8N5B7,Q9Y3A3,Q9P035,Q8TBA6,P10321,Q6NUQ4,Q96RD7,P53365,P16615,O75845,P49755,P04035,Q9BTU6,Q9UP83,Q9NP80,P42345,Q7Z2K6,Q13190,Q10713,Q53GQ0,O00429,O00560,P27824,Q9Y320,Q9UBU6,Q96S66 209 +Mitochondrial envelope 0.5445770448123644 6.2635194832147985 3.763841035893615e-10 3.440150124862394e-07 7.425679407725129e-08 341 O43169,Q8WY22,Q9Y2R0,Q9UDW1,O75880,O60830,Q8N4H5,P52789,P09601,Q9NS69,O14949,Q8N2A8,Q9UDX5,Q6PI78,Q99595,O75027,P00846,O43676,Q8NBN7,Q96TA2,Q9Y6C9,Q9NZ45,Q96A26,Q69YU5,O75964,Q9Y584,Q9H2D1,Q9BRJ2,O14925,Q16134,P22830,Q96CU9,P57105,Q99623,P03886,Q8WWC4,Q13423,P50416,P13073,Q9UBX3,Q86UT6,P21796,Q9UG56,Q9UJZ1,P14406,Q9H061,Q9H2V7,Q9NVH1,Q8N0X7,Q9Y512,Q9NR28,P45880,Q9BSK2,Q70HW3,Q9P0J0,Q9P0S9,Q7KZN9,Q9NUQ2,Q9NQ88,P24539,P23786,P33897,Q96IX5,Q86Y39,Q9Y6N1,Q9H4A6,O00264,Q13637,Q15070,Q9NP58,Q5XKP0,Q96E52,Q9BWH2,Q9H2W6,Q96B49,Q8TB36,Q13505,P00403,Q9Y5J9,Q9NQZ5,Q9Y277,Q9UKU0,O75746,Q6DKK2,Q9HCL2,Q96RL7,Q96D53,O60313,Q567V2,Q07820,O60220,P12235,Q9Y619,O00584,Q9BUR5,Q15388,Q16891,Q9NZJ7,Q9Y255,Q8N8Q8,Q9NVI7,Q9Y5J6,O95139,Q8IYU8,Q7Z7H8,P12236,Q6UXV4,Q9NPL8,O43615,O95202,Q9H3K2,O75208,Q9NX63,Q12981,Q9BUB7,Q9H300,Q9BQT8,O96000,P56378,Q9Y3D6,P30536,Q5HYK3,Q96AY3,Q8NAN2,Q5T9A4,Q9BPX6,P56385,O14548,Q53H12,P21912,Q9Y5L4,Q6UX07,Q13084,P06576,P05141,Q9Y371,Q9HC21,Q96I36,Q8IWA4,Q9NP80,P42345,Q6NUK1,Q10713,Q9NWR8,O00429,Q9Y320,Q9NRA0 147 +Endoplasmic reticulum 0.5406715037927585 6.251619237517762 4.062187849805868e-10 3.712839015357829e-07 7.425679407725129e-08 532 Q9BQE5,P43307,P24390,P09601,P49458,P80303,P52789,P67812,Q8NHH9,O75787,O15258,O14678,P46977,P30519,Q9H490,Q4ZIN3,Q70UQ0,Q8N511,P37268,O95197,P55327,Q9Y4P3,P51648,Q9P2K2,Q9H3N1,Q15005,Q13510,Q15006,Q14257,O60725,Q9HD47,Q9P2W9,Q6ZXV5,Q86UE4,Q86YV9,Q8NBJ4,Q86YN1,P62942,O15173,Q7L0J3,Q5VYK3,O60506,Q92604,Q9Y680,P26885,O15498,Q07065,O43731,P49257,Q15800,Q9Y3A6,O95302,P10619,O75844,O43493,O14735,Q5JRA6,Q86XL3,Q13438,Q8N0U8,Q9H2J4,Q9Y5M8,Q9BRK5,O95070,P01889,O15460,Q9BRR6,Q14108,Q00765,Q9UBV2,Q9NUQ2,P35613,A1L0T0,O95772,Q12768,Q8WXH0,Q99640,Q96PC5,P33897,P61026,Q96G23,Q12907,O00264,Q92791,Q8N4V1,Q969X5,Q15629,Q13637,Q9NP58,Q16880,Q9NZ01,Q9NZ08,Q96CS3,Q96LJ7,Q9NQC3,P61019,O00400,P51572,Q15392,O95881,P05023,P52292,Q9H2C2,Q08431,Q5T9L3,Q9H0U4,Q01105,O95470,Q6NUK4,Q8TB61,Q96A33,P04062,Q92643,Q5BJF2,Q9BUN8,P98164,P62820,P07099,P27105,Q9H6E4,O75503,Q5VV42,Q9UKU0,Q8IV08,Q9HD20,Q9NTJ5,Q9BTV4,O43681,Q96RL7,Q8N5M9,O60476,O14681,Q9P2J5,Q8TCT8,Q969V3,Q9NWM8,O95674,A0FGR8,Q9H173,Q9Y6I9,Q16850,O43390,Q9GZP9,Q86UP2,Q96HY6,Q9Y282,Q13586,Q10472,O00584,Q99720,Q9NPA0,Q04656,Q96JH7,Q969M3,Q9BTY2,Q15904,Q8TCD1,Q96KC8,Q14739,P04844,Q9BUR5,Q6NTF9,O43852,O60427,Q8TCT9,Q99735,Q06136,Q8TEM1,P61916,Q96RQ1,Q8IY95,Q32P28,P04843,Q15363,Q14849,Q02818,Q9Y3E0,O76024,P05067,Q9Y2B0,P38435,O15260,P48723,Q9BRK0,Q8NF37,Q14534,O43292,Q03518,Q86TM6,O15118,P27544,P50402,P51571,Q96A57,Q12981,Q15125,Q9BT22,Q9H6V9,Q92542,Q96N66,P16435,Q9Y3D6,Q8N2F6,P30536,Q5H8A4,Q96JJ7,Q9BSR8,Q9NV96,Q96AY3,Q9H6H4,O15269,Q96AA3,Q9UHB9,O14653,Q8WVM8,P04439,Q8N5B7,Q9H9S5,Q9P035,P07237,P10321,Q6NUQ4,Q96RD7,P13674,P16615,O75845,P49755,P04035,Q9NR31,Q9NP80,P42345,Q7Z2K6,Q13190,Q53GQ0,Q8TBX8,O00429,O00560,P27824,Q9Y320,Q9NRA0,Q06481,Q13217,Q9UBU6,Q96S66 244 +Intrinsic component of organelle membrane 0.6845099510372169 6.1422665136750405 8.135220896190461e-10 7.435589146881924e-07 1.239265318043014e-07 151 Q9Y2R0,O75880,O60830,Q99595,O15258,Q9H490,Q9Y4P3,Q5SNT2,O43808,Q15006,O14925,Q16134,Q86Y82,Q86YN1,Q7L0J3,P57105,P50416,Q9UG56,Q9NVH1,Q9Y512,O75844,O43752,Q86XL3,O95070,P01889,P33897,Q9Y6N1,Q969X5,Q8N4V1,Q15629,Q9NP58,Q9NZ01,Q15070,Q9NQC3,P51572,Q5XKP0,Q9BWH2,Q8TB36,Q5T9L3,Q13505,Q92643,O95470,Q8TB61,Q96A33,Q9BUN8,O60499,Q9H9B4,Q8N2H4,Q9BTV4,O43505,Q8TCT8,P61020,P42892,A0FGR8,P12235,Q9GZP9,Q86UP2,Q9Y282,O95563,Q13586,Q9NPA0,Q14739,Q9BUR5,Q6NTF9,O94901,Q9Y287,Q8TCT9,Q15388,Q16891,L0R6Q1,O76024,Q9UM00,Q8N8Q8,O43819,Q9P0I2,Q6ZRP7,O43292,P57088,Q03518,Q6UXV4,Q86TM6,O15118,Q99442,O96008,Q9H3K2,Q9NX63,Q9GZY8,Q12981,Q15125,Q9BUB7,Q9Y3D6,Q5H8A4,Q9UH99,P13473,P04439,Q9BPX6,Q9P035,Q53H12,P20020,P10321,Q9HC21,Q8IWA4,Q9NWR8,P27824 104 +Vacuole 0.4740093601557649 5.269425343369197 1.3685151632585612e-07 0.0001250744720175 1.7868897988963786e-05 245 P36543,O75787,P50897,Q9UMR5,O14678,Q9HC07,Q8N511,Q9BXS5,P17900,Q8IW92,Q13510,P22413,O15400,Q86YV9,O14773,P07602,Q99538,P15291,P10253,Q07065,Q9UHG3,Q9H2V7,P10619,Q12846,Q8NHP8,Q14108,Q92820,O95772,P33897,Q9NP58,Q96CS3,P61019,P16278,Q9HD42,Q5BJF2,P98164,P04062,P54802,Q07954,Q8WTV0,P27105,Q9NQX7,O75503,O75955,Q8IV08,Q9NX40,Q9Y2T2,O43681,Q96RL7,Q9P2J5,Q8TCT8,Q969Q5,P42892,Q9Y6I9,Q8NCC3,O00584,P78537,Q9BTY2,P04844,Q9Y3E7,O14964,P51797,P15586,P42785,Q9H267,P61916,Q9NZJ7,Q14849,P06280,Q86WC4,P38435,O15260,Q8NF37,P06865,O15118,Q9UIQ6,Q96A57,P11279,Q9UM22,Q92542,Q16625,Q9NV96,Q8NCG7,Q93050,P13473,Q9H7Z7,O95721,Q15043,Q15165,Q9Y371,O00754,Q9BTU6,Q9Y487,Q9P0T7,P42345,P08236,Q8TBX8,O00560,P51790,Q99758,Q9NRA0,Q13217 102 +Golgi apparatus 0.4884705643570247 5.212848659385651 1.859626050798384e-07 0.0001699553927935 1.9613777645371613e-05 372 P24390,P80303,Q8N2A8,P50897,O15258,Q9NXS2,Q9HC07,Q9BXS5,O95197,P46934,Q96CN9,Q9P2W9,O14773,Q8NBJ4,Q86Y82,P15291,Q5VYK3,Q5VW38,Q8NBN3,O15498,O43731,P49257,Q9Y3A6,Q8WTW3,O43493,O14735,Q12846,O00461,O43752,Q92544,Q9BRK5,O95070,P01889,P40616,Q14108,Q7LGA3,O15127,Q96A49,P35613,Q99640,Q9BZG1,Q969S3,P61026,Q12907,Q9H4A6,Q96M27,Q969X5,Q8N4V1,Q13637,Q9NP58,Q8IZA0,Q8TAD4,P61019,O00400,Q16706,Q15392,P51572,P16278,P52292,Q9H2C2,P05023,Q5T9L3,Q9H0U4,Q8TB61,P98164,P04062,P62820,P49327,Q07954,O60499,Q8N2H4,Q9NQX7,O75503,Q8N4A0,Q8IV08,O95295,Q9NX40,Q9NX62,Q9Y2T2,O95249,Q9NTJ5,Q9BTV4,Q8N1S5,Q96PU5,Q8NCH0,Q96RL7,P11717,O60476,O14681,O43505,P26572,Q04656,Q9Y282,Q10472,Q96JH7,Q969M3,Q9BUR5,Q6NTF9,O94923,O43852,Q9Y287,Q9H267,Q8N1B4,L0R6Q1,P50570,Q96RQ1,Q8IY95,Q14789,Q15363,Q02818,Q9Y3E0,P05067,P06280,O15260,Q8NF37,Q7Z3D4,O15118,Q9UID3,Q96A57,Q7Z6M1,Q7RTS9,Q92542,Q99805,Q9BSR8,Q9NV96,O95159,Q96ED9,Q9NPR9,Q8TD16,Q93050,O14653,Q8WVM8,Q9H7Z7,P04439,Q9Y3A3,O95721,Q92859,Q9H9S5,Q92896,Q8NEY8,Q8TBA6,Q16739,P10321,Q6NUQ4,Q9Y371,P53365,Q15643,P49755,Q9BTU6,Q9NR31,Q9UP83,Q9UI14,P42345,Q13190,Q10713,O00429,P51790,Q96S66 158 +Envelope 0.4885948661011722 5.205827998136182 1.9313347790747322e-07 0.0001765084364073 1.9613777645371613e-05 520 O43169,Q8WY22,Q9Y2R0,Q9UDW1,Q15154,O60830,Q8N4H5,O75880,P52789,P09601,Q9NS69,P80303,O14949,Q8N2A8,Q8N1F7,Q9UDX5,Q6PI78,Q99595,O75027,P00846,Q5JTV8,O43676,Q8NBN7,Q96TA2,Q9Y6C9,Q9NZ45,Q5SNT2,Q96A26,Q69YU5,O75964,Q9Y584,Q9H2D1,Q9BRJ2,O14925,Q16134,Q86UE4,P22830,Q9H1E5,O15173,Q96CU9,Q8NFH5,P57105,Q99623,P03886,Q8WWC4,P41208,Q13423,Q8IXM6,P50416,P13073,Q9UBX3,Q9UG56,P21796,Q9UJZ1,Q86UT6,P14406,Q9H061,Q9H2V7,Q9NVH1,Q8N0X7,O75844,Q9Y512,Q9NR28,P45880,Q9BSK2,Q9H8M7,Q70HW3,P20700,Q9P0J0,Q9P0S9,Q7KZN9,Q9NUQ2,Q9NQ88,P24539,Q8NFH4,P23786,Q8WXH0,P33897,Q96IX5,Q86Y39,Q9Y6N1,Q9H4A6,O00264,P02545,Q13637,Q15070,Q9NP58,Q9NQC3,Q5XKP0,Q96E52,Q9BWH2,Q9H2W6,Q96B49,Q8TB36,Q13505,Q9HD42,Q5BJF2,P15954,P00403,Q9Y5J9,Q9H9B4,Q9C0E2,Q9NQZ5,Q9Y277,Q9UKU0,O75746,Q6DKK2,Q96GC5,Q9BTV4,Q9HCL2,Q96RL7,Q96D53,O60313,P11717,O14681,Q567V2,Q14203,Q9Y6M9,Q07820,P53701,P51970,O95674,O60220,P12235,Q9Y619,P20674,O95563,Q9Y6D9,O00584,Q99720,P78537,Q96KC8,Q14739,Q9Y3E7,Q96C57,Q9BUR5,O94901,Q99735,Q15388,Q16891,Q8TEM1,Q9NZJ7,Q9UJS0,Q9NUT2,Q9Y255,O15504,O15397,P05067,Q9HB71,Q8N8Q8,Q9NVI7,Q9Y5J6,O95139,P42166,O43819,O95168,Q8IYU8,Q7Z7H8,P12236,Q9BYT8,Q6UXV4,Q6ZRP7,P57088,P12270,Q9NPL8,Q96AG4,O15118,O43615,O95202,Q9H3K2,O96008,O75208,P50402,Q8N183,Q9NX63,Q9Y276,Q9GZY8,P42167,Q12981,Q15125,Q9BUB7,Q9H300,Q9BQT8,O96000,P56378,Q9Y3D6,P30536,Q5HYK3,Q96AY3,Q8NAN2,Q8TD16,Q9UH99,Q9BTX1,Q5T9A4,Q9BPX6,Q9P035,Q7Z3B4,P56385,O14548,Q53H12,P21912,Q9Y5L4,Q6UX07,Q13084,P06576,P05141,O95373,Q9Y371,Q9BW91,Q9HC21,Q96I36,Q8IWA4,Q9NP80,P42345,Q6NUK1,Q03252,Q10713,Q9NWR8,O00429,O00560,Q9Y320,Q9NRA0,Q96S66 223 +Golgi membrane 0.6021385022107287 5.140842539184985 2.7350920002099697e-07 0.0002499561987498 2.499874088201052e-05 151 P24390,O15258,Q9NXS2,Q9HC07,Q9BXS5,O95197,Q96CN9,Q9P2W9,Q86Y82,P15291,Q8NBN3,O15498,O43731,P49257,Q8WTW3,O00461,O43752,O95070,P01889,P40616,Q14108,Q7LGA3,P35613,Q99640,P61026,Q12907,Q9H4A6,Q969X5,Q8N4V1,Q9NP58,Q8IZA0,P61019,Q16706,O00400,P51572,Q15392,P52292,Q5T9L3,Q9H0U4,Q8TB61,P62820,O60499,Q8N2H4,Q8N4A0,Q8IV08,O95295,O95249,Q9NTJ5,Q8NCH0,P11717,O60476,O43505,P26572,Q9Y282,Q10472,Q9BUR5,Q6NTF9,O94923,Q9Y287,L0R6Q1,P50570,Q14789,Q15363,Q9Y3E0,O15260,Q8NF37,O14653,Q8WVM8,Q9H7Z7,P04439,O95721,Q9H9S5,Q92896,Q8TBA6,Q16739,P10321,Q9Y371,Q15643,P49755,Q9UP83,P42345,Q13190,Q10713,P51790,Q96S66 85 +Membrane protein complex 0.4632598871279725 4.844568604510507 1.2688706984090757e-06 0.0011590763056828 9.8296745186727e-05 319 Q9UDW1,P06756,O60830,Q8N4H5,P36543,P49458,Q9NS69,O14949,P67812,Q99595,O75787,P00846,O14678,P46977,O43676,Q9C0H2,Q9H490,Q8N511,O75964,Q9Y584,Q15005,Q15006,O14925,Q9P2W9,O15400,Q86Y82,P62942,Q96CU9,Q99623,P03886,O15498,P13073,P21796,P14406,Q9NVH1,Q9Y512,Q9NR28,P45880,Q12846,O43752,Q13438,Q9Y5M8,P01889,Q9P0J0,Q9UBV2,P24539,Q8WXH0,Q96IX5,Q86Y39,Q8N4V1,Q9NP58,Q9BRG1,Q96CS3,Q5XKP0,P05023,Q9HD42,Q13505,Q92643,P15954,P49327,P00403,Q9BUN8,O60499,Q07954,O75955,Q9Y277,P02786,Q9Y2T2,O95249,P11717,Q9Y6M9,P51970,P12235,Q9GZP9,P20674,Q9NPA0,P04844,Q15904,Q9Y3E7,Q9BUR5,Q6NTF9,O94901,Q8TCT9,Q15388,Q16891,Q9H267,Q9NUT2,Q86WC4,Q9Y5J6,O95139,Q8IYU8,P12236,Q6UXV4,O43292,Q03518,Q86TM6,P51571,Q9NX63,Q12981,O96000,P56378,Q92542,O15269,Q93050,Q9UH99,O14653,P04439,O95721,Q92859,Q9BPX6,P56385,O14548,Q53H12,P10321,P21912,P06576,P05141,P49755,Q9NR31,Q8IWA4,Q9Y487,Q13190,Q53GQ0,Q9NWR8,O00560,Q9UBU6,Q96S66 127 +Lysosomal lumen 0.7656880180911111 4.841203990339773 1.2905480768488076e-06 0.0011788662939283 9.8296745186727e-05 36 P13473,Q9NZJ7,P50897,Q9UMR5,P06280,P16278,P38435,P17900,P04062,P54802,Q13510,P06865,O14773,P07602,Q8IV08,P10253,O00754,Q9UM22,P10619,O00584,Q8NHP8,Q14108,P15586 23 +Endoplasmic reticulum golgi intermediate compartment membrane 0.72335756435705 4.215331507600301 2.494115461804114e-05 0.0225386226910107 0.0017535550246838 30 Q12907,P24390,O14653,Q96RQ1,Q969X5,Q15363,P61019,P51572,Q8N511,O15260,Q9H0U4,Q03518,Q15643,P49755,O15498,P49257,Q9Y3A6,Q13190,Q9Y282,Q10472,O95070,Q15904 22 +Intrinsic component of mitochondrial membrane 0.6755498018114695 4.190796884382639 2.7797642535576372e-05 0.0250873467542845 0.0018147889483941 54 Q15388,Q16891,O75880,O60830,Q9Y2R0,Q9Y6N1,Q9NP58,Q99595,Q15070,Q8N8Q8,Q5XKP0,Q9BPX6,Q9BWH2,Q8TB36,Q13505,O43819,Q53H12,Q00325,Q6UXV4,O14925,Q9H9B4,Q16134,O96008,Q9H9P8,Q9H3K2,P57105,O95140,Q9NX63,Q9GZY8,Q9HC21,P50416,Q8IWA4,Q9UG56,Q9BUB7,Q9Y4W6,Q9NVH1,P12235,Q9Y512,Q9Y3D6,Q9NWR8,Q6P4A7,O95563,Q8NE86,P17152,Q9BUR5 45 +Intrinsic component of endoplasmic reticulum membrane 0.6667607217116394 4.109690508357496 3.9618974799315865e-05 0.0355646325337534 0.0023330070514643 60 Q8TCT9,Q969X5,Q8N4V1,Q15629,Q9NZ01,P04439,O76024,Q9UM00,Q9NQC3,P51572,Q9H490,Q9P035,Q9Y4P3,O95470,Q92643,Q8TB61,Q96A33,Q9P0I2,Q9BUN8,Q15006,O43292,Q03518,P57088,P10321,Q86TM6,Q86YN1,Q12981,Q15125,Q8TCT8,A0FGR8,O75844,Q9GZP9,Q86UP2,Q9Y282,Q13586,Q86XL3,Q9NPA0,Q5H8A4,P27824,P01889,Q6NTF9 41 +Intrinsic component of mitochondrial inner membrane 0.6773906947786814 4.102673231466476 4.084038602125695e-05 0.0366407416187632 0.0023330070514643 35 Q9Y2R0,Q16891,O75880,O60830,Q9Y6N1,Q99595,Q15070,Q8N8Q8,Q5XKP0,Q13505,O43819,Q53H12,Q00325,Q6UXV4,O14925,Q9H9B4,Q16134,Q9H3K2,Q9H9P8,Q9NX63,Q9HC21,Q9UG56,Q9Y4W6,Q9NVH1,Q9Y512,Q9NWR8,Q6P4A7,O95563,Q8NE86,P17152,Q9BUR5 31 +Azurophil granule membrane 0.7269829059015243 3.915831125866022 9.009329705955692e-05 0.0790494935665209 0.0048438396183785 24 Q92542,O15260,P10253,P13473,Q9NZJ7,Q8NF37,Q07065,P11279,P27105,Q9NV96,Q9NQX7,P07602,P42785 13 +Vesicle membrane 0.4097230798687043 3.8696940220776983 0.0001089720300635 0.0948058815001815 0.0055333575265601 298 P06756,P24390,P11233,O75787,P30519,Q9HC07,Q8N511,Q9BXS5,P55899,O15400,Q86YV9,P07602,Q86Y82,Q7L0J3,P15291,P10253,O15498,Q07065,O43731,P49257,O43493,Q12846,O00461,O43752,P01889,Q14108,O15127,P35613,O95772,Q9BZG1,P61026,O00264,Q8N4V1,Q13637,Q9NP58,Q9BRG1,Q8TAD4,O15439,Q08431,Q9HD42,Q5T9L3,P98164,P62820,Q07954,O60499,Q8WTV0,P27105,Q9NQX7,Q8IV08,P02786,O95295,Q9Y2T2,Q96RL7,P11717,Q8TCT8,Q969Q5,P61020,P42892,Q08722,Q04656,Q15904,Q9Y3E7,P51797,Q9Y287,P42785,Q8N1B4,Q5KU26,Q9NZJ7,Q9NZC3,Q15363,Q14849,O76024,O15260,Q8NF37,Q03518,O15118,Q9UIQ6,P11279,Q7Z6M1,Q92542,Q99805,Q96JJ7,Q96L92,Q9NV96,Q93050,Q9UH99,O14653,P13473,P04439,Q5T9A4,O95721,Q15043,P20020,P10321,Q15643,P49755,O43760,Q9NR31,Q9Y487,Q9P0T7,Q13190,O00429,P51790,Q99758,Q06481 105 +Mitochondrial protein containing complex 0.4727364898761848 3.827423959493621 0.0001294913688594 0.1116262854303486 0.0062292163756586 161 Q15388,Q9UDW1,Q16891,O60830,Q8N4H5,Q86Y39,Q9NS69,O14949,Q99595,P00846,O43676,Q5XKP0,Q9BPX6,Q9Y5J6,O95139,Q13505,P56385,O14548,Q8IYU8,Q53H12,O75964,Q9Y584,Q7Z7H8,P00403,P12236,Q15118,Q9Y5J9,Q9BRJ2,O14925,Q6UXV4,P21912,P21953,Q9Y5L4,Q13084,P06576,P05141,Q96CU9,Q99623,Q9NX63,P03886,P13073,Q567V2,Q8IWA4,P21796,P14406,Q9NVH1,O60220,Q9Y512,P12235,O96000,P56378,Q9NWR8,Q9P0J0,Q9BUR5,P24539 55 +Vacuolar membrane 0.5091121301926433 3.6755469645413408 0.0002373403726809 0.1950336854520544 0.0108464550315204 145 P33897,Q9H267,P36543,Q93050,P13473,Q9NZJ7,O75787,Q9NP58,O14678,Q14849,P61019,O95721,Q9HC07,Q86WC4,Q8N511,Q9BXS5,O15260,Q9HD42,P98164,P04062,Q8NF37,Q07954,Q15043,P22413,Q8WTV0,P27105,O15400,Q9NQX7,Q86YV9,O75503,O75955,P07602,O15118,Q9UIQ6,Q8IV08,Q9Y371,P15291,Q9Y2T2,P10253,Q96RL7,Q9BTU6,Q07065,P11279,Q8TCT8,Q9Y487,Q9P0T7,P42892,Q9H2V7,P42345,P10619,Q9Y6I9,Q92542,Q16625,P78537,P04844,P51790,Q99758,Q9Y3E7,Q14108,Q9NV96,Q8NCG7,Q9NRA0,P51797,O95772,P42785 65 +Trans golgi network membrane 0.6337428245045551 3.6542838078598794 0.0002579008683611 0.2100232744509438 0.0108500029141585 33 Q8WTW3,Q9BXS5,Q8N1B4,P53365,Q9NX62,O43752,O60499,P11717,P40616,Q8N2H4,Q9UP83,P05067,Q7Z6M1,O15127,Q9HC07,Q9UID3 16 +Endosome 0.3902847494282676 3.641273028685161 0.0002712932392929 0.2196366715196428 0.0108500029141585 256 P36543,O75787,Q9HC07,Q13510,P55899,O15400,Q86YV9,O14773,P07602,Q86Y82,Q99538,Q5VYK3,Q5VW38,O15498,O43493,Q12846,O00461,O43752,Q92544,Q9BRK5,P01889,Q14108,O15127,P35613,Q12768,O95772,P61026,Q9H4A6,Q8N4V1,Q13637,Q9NP58,Q9BRG1,Q9HD42,Q5T9L3,P98164,P62820,Q07954,Q9BUN8,O75955,Q8IV08,P02786,Q9NX40,Q96PU5,Q96RL7,P11717,Q8TCT8,Q969Q5,P61020,P42892,Q9GZP9,Q04656,Q15904,Q9Y3E7,O14964,P51797,Q9Y287,Q9H267,Q8N1B4,P50570,Q8IY95,Q9NZJ7,Q14849,P05067,O15118,Q9UIQ6,Q9UID3,Q96A57,P11279,Q7Z6M1,Q92542,Q99805,Q96L92,Q9NV96,Q93050,Q9UH99,O14653,P13473,P04439,Q9UGJ1,Q15043,P10321,Q8IZ07,Q9BTU6,Q9Y487,Q9P0T7,P51790,Q99758,Q06481 88 +Intrinsic component of plasma membrane 0.5974537075032748 3.639629399935276 0.0002730307079055 0.2208752779843404 0.0108500029141585 96 P06756,Q12907,Q9H2J7,O00264,Q9UJS0,P53985,O96005,P04439,Q8TAD4,P05067,O00400,P10586,P51572,P23634,P05023,P55011,Q92859,O43657,Q9BRK0,Q07954,Q9BZM4,Q15043,P20020,P10321,P22413,Q8WTV0,P27105,P05026,Q9H1Z9,Q96QD8,Q8NBJ4,O15118,Q15375,Q9UIQ6,P05141,P02786,O15031,P16615,O60637,P11717,O15498,Q9BTU6,P11279,A0FGR8,P12235,Q08722,Q92542,Q9NR28,Q99805,Q86UP2,Q13586,P30825,O00560,P27824,P51790,P01889,P33527,P35613,Q8NAN2 59 +Outer membrane 0.5859423846254236 3.553473900980481 0.0003801789186526 0.2935830261758665 0.0144784804853534 99 O43169,Q8WY22,Q8WXH0,Q15388,Q16891,Q8N4H5,P52789,P09601,Q9NS69,O00264,Q9NZJ7,Q8N2A8,Q13637,Q9NP58,Q9Y6C9,Q5XKP0,Q9BWH2,Q96B49,Q9NZ45,Q13505,Q53H12,Q6UXV4,Q9NQZ5,Q9Y277,Q9UKU0,Q9Y371,P57105,Q99623,P50402,Q9NX63,Q9HCL2,Q96RL7,O60313,P50416,Q8IWA4,Q86UT6,P21796,Q07820,P42345,Q9NVH1,Q8N0X7,Q9Y512,P45880,Q9Y3D6,Q99720,P30536,O00429,Q9BUR5,Q9NUQ2,Q9NQ88,Q8NAN2 51 +Inner mitochondrial membrane protein complex 0.5999494275671338 3.542439694145115 0.000396444058424 0.3040112023550204 0.0144939947759849 81 Q9UDW1,Q16891,O60830,Q86Y39,O14949,Q99595,P00846,O43676,Q5XKP0,Q9BPX6,Q9Y5J6,O95139,Q13505,P56385,O14548,Q8IYU8,Q53H12,O75964,Q9Y584,P00403,P12236,Q6UXV4,O14925,P21912,Q96CU9,Q9NX63,P03886,P13073,P14406,O96000,P56378,Q9P0J0,Q9BUR5,P24539 34 +Respirasome 0.5700500488703837 3.295342429437099 0.0009830181462189 0.592991205490612 0.0332769846534852 45 O95139,Q9UDW1,Q96CU9,Q86Y39,O14548,Q6DKK2,P03886,O14949,P00403,Q13423,Q9P0J0,P13073,Q7KZN9,O43676,P14406,O96000 16 +Endoplasmic reticulum golgi intermediate compartment 0.5739295785402775 3.2768882324190733 0.001049579078403 0.6170378304980134 0.0342612599164435 55 Q12907,P24390,O14653,Q96RQ1,Q969X5,P80303,O15258,Q15363,Q02818,P61019,P51572,Q8N511,P07237,O15260,Q03518,Q5VYK3,Q15643,P49755,O15498,P49257,Q9Y3A6,Q13190,Q9Y282,Q10472,O95070,Q15904 26 +Copii coated er to golgi transport vesicle 0.5625169867995531 3.2328370152630472 0.0012256746889725 0.6740312524003877 0.0375854442953902 37 Q5VYK3,Q12907,Q9Y282,O14653,Q96RQ1,P49755,O95070,P01889,P10321,Q9NR31,Q15363,P04439,P05067,P49257,Q9Y3A6,Q13190 16 +Vacuolar lumen 0.5695730737148219 3.2094579935443233 0.0013298547675257 0.7036743277903759 0.0392092663715667 67 P13473,Q9NZJ7,Q9H7Z7,P50897,Q9UMR5,P06280,P16278,P38435,P17900,P04062,P54802,Q13510,P06865,O14773,P07602,Q8IV08,P10253,O00754,Q9UM22,P10619,P08236,O00584,O00560,Q9BTY2,Q8NHP8,Q14108,P15586 27 +Secretory granule membrane 0.5625055938379706 3.1652846557241494 0.0015493129791719 0.7576010040042498 0.0438599631457358 81 P06756,P61026,Q93050,O00264,Q9NZJ7,P13473,O75787,Q15363,Q5T9A4,P30519,Q8TAD4,O95721,O15439,Q08431,Q9BXS5,O15260,Q8NF37,P10321,P27105,Q9NQX7,P07602,P15291,P10253,Q15643,P49755,P11717,Q07065,P11279,Q969Q5,Q08722,Q92542,Q96JJ7,P01889,Q99758,Q9NV96,Q06481,P35613,P42785 38 +Outer mitochondrial membrane protein complex 0.7273108296819563 3.153224259901236 0.001614777020316 0.7717010011376287 0.0438599631457358 16 Q15388,Q16891,Q13505,Q8N4H5,Q9NS69,Q9NX63,Q6UXV4,Q8IWA4,Q9BUR5,Q5XKP0,Q9NVH1 11 +Golgi cisterna 0.5950840114449802 3.1502062730723277 0.0016315522395569 0.7751803129028588 0.0438599631457358 28 Q9BZG1,P15291,Q10713,O95249,O00461,Q9H4A6,Q10472,Q8NBN3,Q8TBA6,Q8WVM8,Q96CN9,P04439,Q15363,Q9Y3A3,Q16706 15 +Endocytic vesicle membrane 0.5526155387985561 3.1198517070167195 0.0018094210738428 0.8089669613977507 0.0472517388997819 47 Q9BZG1,P61026,Q93050,Q5KU26,P13473,Q13637,P04439,Q5T9L3,P98164,Q07954,P10321,Q03518,Q8WTV0,P02786,P11717,P11279,Q9Y487,O43493,Q12846,Q04656,P01889,Q14108,Q06481 23 +Snare complex 0.6805689897114351 3.088160187289742 0.0020139987833975 0.8416030508169534 0.0503808744779492 19 O95249,O43752,O14653,Q12981,O60499,O15498,Q9P2W9,O15400,O95721,Q86Y82,Q13190 11 +Cytochrome complex 0.7017842854357575 3.0822843657464603 0.0020541849901198 0.8473268806300658 0.0503808744779492 17 Q9UDW1,O14949,P13073,Q7KZN9,P14406 5 +Endoplasmic reticulum tubular network 0.7280669696753348 3.07647912898773 0.0020946096610088 0.8528762296765989 0.0503808744779492 15 Q9H2C2,P50402,Q13586,Q6NUK4,Q9BRK0,Q8NHH9,Q00765,Q9NQC3,Q9H6H4 9 +Proton transporting two sector atpase complex 0.5885383342801465 3.0378288334691814 0.0023828926263667 0.8870220844725695 0.0558452271922864 26 Q8N511,P56385,P36543,Q93050,O75964,Q15904,P00846,Q9Y487,P06576,P56378,P24539 11 +Cis golgi network 0.6693032496982061 3.013186468470938 0.0025852001751902 0.9061382650220992 0.0576310478078999 19 Q9NPR9,O95249,O00461,P24390,Q8TBA6,Q8WVM8,Q15643,P49755,Q14789,P30533,O43731,Q16706,Q9Y3A6 13 +Organelle membrane contact site 0.6657331208651053 2.989293363500143 0.0027962351315085 0.922644131601356 0.0608514026237803 19 Q96N66,Q15388,O95772,Q9NTJ5,P27824,Q13637,Q9Y320,Q14849,P51572,Q5XKP0,A0FGR8,Q96S66 12 +Nuclear envelope 0.3402715674995809 2.8986280994375693 0.0037479916935585 0.9676810060829574 0.0796666141375003 185 Q8WXH0,Q15154,Q99735,Q8TEM1,Q8TD16,Q9UH99,P80303,Q8N1F7,P02545,Q9BTX1,O15504,Q5JTV8,Q9NQC3,O15397,P05067,Q9HB71,P42166,Q9P035,Q9HD42,Q5SNT2,Q7Z3B4,Q5BJF2,Q6ZRP7,P57088,P12270,Q9C0E2,Q86UE4,O15118,O95373,Q8NFH5,Q9H1E5,O15173,Q9BW91,P50402,Q9BTV4,P42167,P41208,Q12981,P11717,Q15125,Q8IXM6,O14681,Q14203,P42345,Q9H2V7,O75844,Q03252,Q9Y6D9,Q99720,Q9H8M7,O00560,P20700,Q96KC8,Q14739,Q96C57,Q9Y3E7,Q9NUQ2,O94901,Q96S66,Q8NFH4 60 +Transport vesicle membrane 0.523473121951564 2.828087470341057 0.004682700995789 0.986295637381739 0.0931017305077865 49 O14653,Q15363,P04439,O76024,P62820,O60499,P20020,P10321,Q86Y82,O95295,Q7L0J3,P49755,O43760,Q9NR31,P49257,Q13190,O43752,O00429,P01889,Q9NV96 20 +External side of plasma membrane 0.5487867391605717 2.7684806027606146 0.0056318337968663 0.9942700338997804 0.0997996724529518 28 P02786,P07237,P06756,P15291,P98164,P49327,P55899,O96005,O75787,P51790,P04083,P11279,P42892,P08183,O75955,O15439,Q08431 17 +Exocytic vesicle 0.5106811420374509 2.7616684562552374 0.005750684186081 0.99486305480511 0.0997996724529518 42 P61026,P50897,Q9BT78,O76024,P05067,O60499,P20020,O15400,Q86Y82,O95295,Q7L0J3,Q96A57,Q92905,O43760,P11279,Q9UI14,Q92542,Q12846,O43752,O00429,P51790 21 +Nuclear inner membrane 0.5971020565525026 2.7611445705117825 0.0057599173277897 0.9949064723753348 0.0997996724529518 22 O75844,Q9H1E5,Q03252,Q5SNT2,P50402,Q9UH99,Q9BTV4,Q99720,P20700,Q8IXM6,Q14739,Q5JTV8 12 +Specific granule membrane 0.6420777955352364 2.7596082712086214 0.0057870707221077 0.99503204484251 0.0997996724529518 18 Q08722,P06756,O00264,Q9NV96,Q07065,P27105,P30519 7 +Apical plasma membrane 0.5164646218551192 2.752829831837891 0.0059082597717041 0.9955558439329262 0.1000027672469928 50 Q14254,Q9NP72,P36543,P53985,Q9Y6M7,O75787,P04083,Q8TAD4,P23634,O15439,P55011,P05023,O15020,P98164,Q15043,Q99808,P20020,P05026,Q86UE4,O75955,P08195,P54709,Q16625,Q04656,P30825,P51790,Q9P289,Q9NV96,P04920,P08183,P35241,P33527,Q99797 33 +Phagocytic vesicle membrane 0.5487906677635268 2.740607527310365 0.0061325712089217 0.9963841478654932 0.1019121833628086 27 Q9BZG1,P61026,Q12846,Q04656,Q93050,P13473,Q13637,P10321,Q03518,P04439,P11279,P01889,Q9Y487,Q06481 14 +Basolateral plasma membrane 0.5074521066670963 2.695109380541979 0.0070365527946407 0.9984260130804036 0.1108863664534769 46 P53985,Q9Y6M7,P04083,P23634,O15439,P05023,P55011,Q14168,Q07954,Q15043,P20020,P22413,P05026,O75955,P02786,P15291,P57105,Q6P4Q7,Q04656,Q12846,P30825,P04920,P33527,P35613 24 +Organelle envelope lumen 0.5009967425489418 2.68762265696052 0.0071962667197591 0.998641220292645 0.1114811488450824 40 Q16891,Q9H4A6,Q9Y255,P05067,Q9HB71,Q9BPX6,Q9Y5J6,Q53H12,Q8IYU8,Q9Y5J9,O14925,Q9Y5L4,O60313,P11717,Q9UJZ1,P51970,O60220,Q9NR28,O00584,P78537,Q96AY3 21 +Intrinsic component of mitochondrial outer membrane 0.6628482320703988 2.6774114988135955 0.0074193450498569 0.998893510440698 0.112092597877181 15 O96008,Q9BWH2,Q8TB36,Q15388,P57105,Q9Y3D6,Q9NP58,P50416,Q8IWA4 9 +Synaptic vesicle membrane 0.6383519399124709 2.673383105083445 0.007509044123948 0.9989812351754448 0.112092597877181 17 O95295,Q7L0J3,O43752,O00429,O43760,O60499,P20020,O76024,Q86Y82 9 +Transport vesicle 0.5004779726794742 2.669180595086722 0.00760365543587 0.9990662459549778 0.112092597877181 105 P61026,P24390,O14653,P50897,Q15363,P04439,O76024,P05067,Q9BT78,O15260,Q9H0U4,P62820,Q8TBA6,O60499,P20020,P10321,O15400,Q86Y82,O95295,Q7L0J3,O95249,Q96A57,Q15643,Q92905,P49755,O43760,P11717,O15498,Q9NR31,P11279,O43731,P61020,Q9UI14,P49257,Q7Z6M1,Q13190,Q92542,O43493,Q12846,O00461,O43752,O00429,P51790,P01889,Q9NV96 45 +Intrinsic component of synaptic vesicle membrane 0.716210587439297 2.636399842709174 0.0083790932280305 0.9995429680159248 0.1196639251628112 12 Q7L0J3,O43752,O60499,P20020,O76024,Q86Y82 6 +Microbody membrane 0.5136100933608 2.622253157788679 0.0087350518977986 0.9996708218452716 0.1221447645996096 33 P33897,O75381,P51648,Q9Y3D6,O43808,Q15067,P04035,Q9BY49,Q9NR77,O14678,P40855,Q9NP80,Q9UKU0 13 +Tim23 mitochondrial import inner membrane translocase complex 0.8382183656833263 2.618950230506808 0.0088200814699936 0.9996956452774328 0.1221447645996096 7 Q99595,O14925,O60830 3 +Golgi apparatus subcompartment 0.4893930423238103 2.5855806087434363 0.0097215138136386 0.9998675010287282 0.1269351946523671 109 Q9BZG1,Q9NPR9,P61026,Q8N1B4,Q9H4A6,P50570,Q8WVM8,Q13637,Q15363,P04439,Q9Y3A3,P05067,Q16706,P51572,Q9HC07,Q9BXS5,Q5T9L3,P04062,Q8TBA6,Q96CN9,O60499,Q8N2H4,Q9UID3,P15291,Q5VYK3,Q9NX62,O95249,P53365,Q8NBN3,Q96A57,P11717,Q9BTU6,Q9UP83,Q7Z6M1,Q8WTW3,O43493,Q96ED9,Q12846,Q04656,O00461,O43752,Q10472,Q96JH7,Q10713,Q969M3,P40616,Q9BSR8,O15127 48 +Golgi associated vesicle membrane 0.5599455181836814 2.571902406616573 0.0101141398384503 0.9999077852658186 0.1296521757523394 23 Q8N511,P24390,Q8TCT8,O43731,Q9Y287 5 +Intrinsic component of golgi membrane 0.7272090409783476 2.526852848040758 0.0115089713434 0.9999745857593074 0.1377020060617128 11 L0R6Q1,Q9Y282,Q8TB61,Q969X5,O95070,Q6ZRP7,O15258,O43505,Q8N2H4 9 +Integral component of synaptic vesicle membrane 0.8167293528932497 2.5178536374251665 0.0118072374145077 0.9999807120833768 0.1377020060617128 7 O43752,O60499,P20020,O76024,Q86Y82 5 +Azurophil granule 0.5014109661666483 2.5140998471713036 0.0119336642336269 0.9999828407643964 0.1377020060617128 72 P13473,Q9NZJ7,Q9H7Z7,O95721,P06280,P16278,O15260,P17900,Q8NF37,P06865,P27105,O15400,Q9NQX7,P07602,P15291,P10253,O00754,Q07065,P11279,P10619,Q92542,P08236,O00584,O00560,Q9BTY2,Q9NV96,Q92820,Q13217,P15586,P42785 30 +Endoplasmic reticulum protein containing complex 0.5003345864984444 2.510597832321768 0.0120526919966488 0.9999846298920668 0.1377020060617128 67 Q8TCT9,P49458,Q8N4V1,P67812,P04843,P04439,Q96CS3,P46977,Q9H490,P07237,Q92643,Q15005,Q9P0I2,Q9BUN8,Q15006,O43292,Q03518,Q86TM6,P13674,P62942,P51571,O43681,Q9UBS4,P14314,Q9GZP9,Q53GQ0,Q13438,Q9NPA0,Q9Y5M8,P04844,Q9UBV2,Q6NTF9,P14625,O15269,Q9UBU6 35 +Er ubiquitin ligase complex 0.766721752014329 2.4869979464368015 0.012882614265725 0.9999928700882564 0.1401751123675317 8 Q9GZP9,Q13438,Q9BUN8,Q86TM6,Q9UBV2 5 +Endoplasmic reticulum lumen 0.4973928720059928 2.475606728122068 0.0133010000342657 0.9999951604512692 0.1430248709566924 69 Q32P28,Q9NZ08,Q02818,P30533,O76024,P05067,Q8NBJ5,O95881,Q96HE7,Q08431,P07237,Q9P2K2,Q9NYU2,Q14257,P30040,P13674,Q8NBJ4,Q8TED1,Q9BTV4,O43681,Q9Y680,Q07065,Q9UBS4,Q9NWM8,Q15293,Q9H173,P14314,Q8IXB1,O43493,Q6P179,P53634,Q96AY3,Q86UP2,P14625,Q5JRA6,Q13438,O00584,Q96JH7,P27824,Q9BTY2,Q9BS26,O15460,O75718,Q06481,Q13217,O43852 46 +Golgi stack 0.4799552057144003 2.4608972759659378 0.0138590040461026 0.999997114251146 0.1472922057923 37 Q9BZG1,P15291,Q10713,O95249,O00461,Q9H4A6,Q10472,Q96JH7,Q8NBN3,Q8TBA6,Q8WVM8,Q96CN9,P04439,Q15363,Q9Y3A3,Q16706,P51572 17 +Proton transporting two sector atpase complex proton transporting domain 0.6827256918062179 2.4453409198864464 0.0144715274628892 0.9999983645897504 0.1514672358908038 12 P56385,Q93050,O75964,P00846,Q9Y487,P24539 6 +Respiratory chain complex iii 0.7471776055766215 2.3879780857826733 0.016941351932439 0.9999998349569412 0.168308648546188 8 Q9UDW1 1 +Golgi associated vesicle 0.4759137672449771 2.381311629435215 0.0172511112164213 0.9999998762625552 0.1684852207377807 36 Q8N511,O43493,P24390,Q8WVM8,Q15363,Q8TCT8,O43731,P05067,Q9Y287 9 +Micos complex 0.908013544018057 2.372094990314918 0.0176875427540232 0.9999999175517256 0.1692558063925729 5 Q6UXV4,Q16891,Q5XKP0,Q9BUR5 4 +Autophagosome membrane 0.6225863786024366 2.3575684710927796 0.018395062570323 0.9999999573248493 0.1733307957657247 14 Q9Y371,Q9HD42,P13473,P04844,O75787,P11279,O95721,Q9Y6I9 8 +Late endosome membrane 0.469862051158206 2.340210349994964 0.0192728815303206 0.999999981161754 0.1744100368189417 44 O14653,P13473,Q9NP58,Q14849,Q9HC07,Q9HD42,Q15043,O15118,Q8IV08,P11279,Q8TCT8,Q9P0T7,P51790,Q99758,Q9Y3E7,Q9NV96,O14964,Q14108,O95772 19 +Mib complex 0.7108200998022988 2.285220364610067 0.0222999096801912 0.9999999988832166 0.1938761186046325 10 Q16891,Q13505,Q9NX63,Q6UXV4,Q9BUR5,Q5XKP0,Q9NVH1 7 +Lumenal side of membrane 0.6828545474491502 2.2820813320767654 0.0224845389191368 0.999999999060271 0.1938761186046325 11 P27824,P01889,P10321,P04439,Q8TCT8,P51572,P10619 7 +Golgi lumen 0.8270397837467238 2.266598006205363 0.0234147940052023 0.9999999996063876 0.1981585344514342 6 Q9NX62,Q9BRK5,O00461 3 +Respiratory chain complex iv 0.6979492789280982 2.2162122276185436 0.0266769708444558 0.9999999999815116 0.2177031370699344 10 O14548,P20674,P15954,P00403,P13073,P14406 6 +Proton transporting atp synthase complex 0.6201118523664655 2.202559246316639 0.0276258289929451 0.9999999999924188 0.2230491341030944 13 P56385,O75964,P00846,P56378,P24539 5 +Late endosome 0.4722948609058029 2.1998134586496834 0.0278201326999483 0.9999999999936844 0.2230491341030944 81 Q9H267,O14653,P13473,Q9NZJ7,Q9NP58,Q14849,Q9HC07,Q9HD42,Q9BUN8,Q15043,O15400,O15118,P07602,Q8IV08,Q99538,Q8IZ07,Q5VYK3,Q96PU5,Q96A57,P11717,P11279,Q8TCT8,Q9P0T7,Q9GZP9,Q04656,Q9BRK5,P51790,Q99758,Q9Y3E7,Q14108,O14964,Q9NV96,O95772 33 +Secretory vesicle 0.327974479655052 2.1963295722146388 0.0280683625503026 0.9999999999949992 0.2230824640954489 284 P06756,O43707,O75787,P50897,Q9NUQ9,P30519,Q9BXS5,Q8NBX0,P17900,Q13510,O15400,P07602,Q86Y82,Q7L0J3,P15291,P10253,Q07065,P10619,P45880,Q12846,O43752,P01889,Q92820,P35613,P61026,O00264,Q96CS3,Q8TAD4,O15439,P16278,Q08431,O60499,P27105,Q9NQX7,O95295,O43681,Q92905,Q96RL7,P11717,Q969Q5,P61020,P42892,Q9Y6I9,Q08722,Q8NBM8,O00584,Q9BTY2,P15586,P42785,Q9NZJ7,Q15363,O76024,P05067,P06280,O15260,Q8NF37,Q6UXV4,P06865,Q96A57,P11279,Q92542,Q96JJ7,Q9NV96,Q08380,Q93050,P13473,Q9H7Z7,Q5T9A4,Q9BT78,O95721,P12956,P20020,P10321,O00754,Q15643,P49755,O43760,Q9Y487,Q9UI14,O00231,P08236,O00429,O00560,P51790,Q99758,Q06481,Q13217 87 +Golgi cisterna membrane 0.5328211013443468 2.188408987180675 0.0286398242238736 0.9999999999970788 0.2237333276976114 21 P15291,Q10713,O00461,Q9H4A6,Q10472,Q8NBN3,Q8WVM8,Q15363,Q9Y3A3 9 +Pore complex 0.7047373393865534 2.169056367258017 0.0300784047525943 0.9999999999992462 0.231022369276229 8 P12235,P45880,Q9Y277,P21796 4 +Er to golgi transport vesicle membrane 0.497109245110341 2.157111805124774 0.030996954015602 0.9999999999996828 0.234142280745953 24 O14653,P49755,P10321,Q9NR31,Q15363,P04439,P49257,Q13190 8 +Lumenal side of endoplasmic reticulum membrane 0.6985869761373236 2.1368885561161957 0.0326070570149559 0.9999999999999306 0.2442856566530304 8 P27824,P01889,P10321,P04439,Q8TCT8,P51572 6 +Copi coated vesicle membrane 0.6084549291435662 2.130347453665622 0.0331429385315555 0.9999999999999584 0.2442955307890468 13 Q8N511,P24390,O43731 3 +Intrinsic component of nuclear inner membrane 0.7316574883739871 2.105706934530941 0.0352298171023186 0.9999999999999942 0.2536130479661627 7 Q9UH99,Q5SNT2,Q14739,Q9BTV4 4 +Hrd1p ubiquitin ligase erad l complex 0.7865303524802304 2.0826265833163866 0.0372852741703635 0.9999999999999992 0.2621441583977867 6 Q9GZP9,Q9BUN8,Q9UBV2 3 +Cortical endoplasmic reticulum 0.8951917391231108 2.077967889658741 0.0377123167461399 0.9999999999999994 0.2624377508563537 4 Q9H2C2,Q13586 2 +Copi coated vesicle 0.5787980382331084 2.075920607459051 0.0379012944343968 0.9999999999999996 0.2624377508563537 14 Q8N511,P24390,Q15363,O43731 4 +Basal part of cell 0.4488396580630833 2.02855390816324 0.0425037472558742 1.0 0.2856184590292211 55 P53985,Q9Y6M7,P04083,P23634,O15439,P05023,P55011,Q14168,Q07954,Q15043,P20020,P22413,P05026,O75955,P02786,P15291,P57105,Q6P4Q7,Q04656,Q12846,P30825,P04920,P33527,P35613,P42785 25 +Presynaptic active zone 0.5431541460345366 2.0225068910788644 0.0431240124136023 1.0 0.2856184590292211 17 Q7L0J3,Q12846,Q99623,Q07021,P27824,P20020,P05067,P23634 8 +Proton transporting atp synthase complex coupling factor f o 0.6738251741852865 2.0062607186555703 0.0448284386827706 1.0 0.2900333579771694 8 O75964,P00846,P24539 3 +Mitochondrial intermembrane space protein transporter complex 0.8775740479548734 2.005204583530777 0.0449411802821715 1.0 0.2900333579771694 4 Q9Y5J9,O60220,Q9Y5J6 3 +Pigment granule 0.4516469401303065 2.0040949794754535 0.0450598871255558 1.0 0.2900333579771694 64 Q93050,Q13637,Q9NP58,P04843,P61019,P05023,P07237,P07900,P55209,P62820,P49327,P27105,O14773,O75955,P02786,P49755,P11279,P61020,Q92542,Q04656,O00560,P27824,O43852,Q92820,P35613,P62258 26 +Multivesicular body membrane 0.660460728924588 1.9944430920981089 0.0461036532247354 1.0 0.2906119934304012 9 Q9HD42,Q8WUX9,Q99758,Q9NP58,Q9Y3E7,O14964,Q9P0T7 7 +Mitochondrion 0.3388127234451483 1.9871827502456336 0.046902148704033 1.0 0.2934218646980376 667 O43169,Q8WY22,Q9Y2R0,Q9UDW1,O75880,O60830,Q8N4H5,P52789,P09601,Q9NS69,O14949,Q8N2A8,Q9UDX5,Q6PI78,Q99595,P11233,O75027,P00846,Q9NUQ9,O43676,Q8NBN7,Q9Y6C9,Q96TA2,P00374,Q9NZ45,Q96A26,Q8NBX0,Q69YU5,O75964,Q9Y584,Q9P0J1,Q9H2D1,Q9BRJ2,O14925,P21953,Q16134,Q07021,P22830,Q96CU9,P57105,Q99623,P03886,Q3SXM5,Q7L592,Q8WWC4,Q13423,O15498,P50416,P13073,Q9UBX3,Q86UT6,P21796,Q9UG56,Q9UJZ1,P14406,Q9UII2,Q9H061,Q9H2V7,Q9NVH1,Q8N0X7,Q9Y512,Q9NR28,O14874,P45880,Q9BSK2,Q70HW3,Q9P0J0,Q9P0S9,Q7KZN9,Q9NUQ2,Q9H6K4,P35613,Q9NQ88,P24539,Q8WXH0,P23786,P33897,Q96IX5,Q86Y39,Q9Y6N1,Q9H4A6,O00264,Q04837,P28070,Q13637,Q15070,Q9NP58,Q9Y2W6,P51572,Q5XKP0,Q96E52,Q9BWH2,Q9H2W6,Q96B49,Q13505,P00403,Q9Y5J9,Q9NR77,P27105,Q9NQZ5,Q9Y277,Q9UKU0,O75746,Q6DKK2,Q9HCL2,Q96RL7,Q96D53,O60313,Q567V2,Q07820,O60220,P12235,Q9Y619,O00584,Q9BUR5,Q15388,Q16891,Q16740,Q9NZJ7,Q6YN16,Q9Y255,Q14849,Q8N8Q8,Q9NVI7,Q9Y5J6,O95139,P48723,Q9NPH0,Q8IYU8,Q7Z7H8,P12236,Q15118,Q6UXV4,O43292,Q9NPL8,O43615,O95202,Q9H3K2,P30153,O75208,Q9NX63,Q12981,Q9BUB7,Q9H300,Q9BQT8,O96000,P56378,Q92542,P16435,Q9Y3D6,Q8N2F6,P30536,Q5HYK3,Q96AY3,Q8NAN2,Q7LG56,Q9H7Z7,Q02790,Q5T9A4,Q9BPX6,P56385,O14548,Q53H12,P21912,Q9Y5L4,Q6UX07,Q13084,P13674,P06576,P05141,Q15165,Q9Y371,Q9BW91,Q16836,Q9HC21,Q96I36,Q9BTU6,Q8IWA4,Q9NP80,Q9NWS8,P42345,Q6NUK1,Q10713,Q9NWR8,O00429,Q9BY49,Q9Y320,Q9NRA0,Q12849 189 +Lipid droplet 0.4388126893057303 1.9817028147164677 0.0475125120079973 1.0 0.2934218646980376 35 P60604,Q01105,Q8NBX0,Q8NBQ5,Q99720,Q8NF37,Q96RL7,O43760,Q8TCD1,Q07065,Q96CS3,Q9H6V9,P51572,Q8N0X7 14 +Secretory granule 0.3116526345696939 1.9638256456674132 0.0495503149276235 1.0 0.3019265856256526 256 P06756,P61026,O43707,Q08380,Q93050,O00264,Q9NZJ7,P13473,Q9H7Z7,O75787,Q15363,Q9NUQ9,Q96CS3,O76024,P30519,Q8TAD4,P05067,P06280,O15439,Q5T9A4,P16278,Q08431,O95721,Q9BXS5,O15260,P12956,Q8NBX0,P17900,Q8NF37,Q13510,Q6UXV4,P10321,P06865,P27105,O15400,Q9NQX7,P07602,O95295,P15291,P10253,O00754,O43681,Q15643,Q96RL7,P49755,P11717,Q07065,P11279,Q969Q5,Q9Y487,P61020,P42892,P10619,Q9Y6I9,Q08722,Q92542,Q8NBM8,P45880,Q12846,O00231,P08236,O00584,O00560,Q96JJ7,P01889,Q9BTY2,P51790,Q9NV96,Q99758,Q92820,Q06481,Q13217,P35613,P15586,P42785 75 +Nadh dehydrogenase complex 0.4618329219266532 1.94816911124704 0.0513947314918874 1.0 0.3095425088884549 25 O95139,Q96CU9,Q86Y39,P03886,Q9P0J0,O43676 6 +Multivesicular body 0.5395075191886015 1.9303878054158752 0.0535588047614554 1.0 0.3143148845301721 16 Q9HD42,Q5VYK3,Q8WUX9,Q96PU5,Q99758,Q9NP58,Q9Y3E7,P11279,O14964,Q9P0T7,P10644 11 +Proton transporting v type atpase complex 0.576508860626373 1.9296780462566812 0.0536467417797668 1.0 0.3143148845301721 13 Q8N511,P36543,Q93050,Q15904,Q9Y487 5 +Extrinsic component of organelle membrane 0.5368795443194816 1.9120985829316823 0.0558635505873066 1.0 0.3252183773044475 16 Q9Y5X3,Q15006,Q5HYK3,Q96BW9,Q96D53,Q8NI60,P04083,P49748,P62942 9 +Trans golgi network 0.4447500516357006 1.88879131524216 0.0589197969582784 1.0 0.3408398381004208 79 Q9NPR9,P61026,Q8N1B4,Q9H4A6,Q13637,P05067,Q9HC07,Q9BXS5,Q5T9L3,P04062,O60499,Q8N2H4,Q9UID3,Q5VYK3,Q9NX62,P53365,Q96A57,P11717,Q9BTU6,Q9UP83,Q7Z6M1,Q8WTW3,O43493,Q96ED9,Q12846,Q04656,O43752,Q969M3,P40616,Q9BSR8,O15127 31 +Endosome lumen 0.7423087778718586 1.8777287658609272 0.060418279439917 1.0 0.340941128397467 6 P98164,Q13637,P05067,Q9UIQ6,Q99538 5 +Apical part of cell 0.4396153335908355 1.8733785988448175 0.0610161231364287 1.0 0.3421394880165394 64 Q15154,P36543,P53985,Q9Y6M7,O75787,P04083,P05067,P23634,Q8TAD4,O15439,P55011,P05023,O15020,P98164,Q15043,P20020,Q86UE4,O75955,Q99538,P41208,Q16625,Q04656,P30825,P51790,Q9NV96,P08183,P33527 27 +Perinuclear region of cytoplasm 0.294023372204713 1.848905028249064 0.0644715275166829 1.0 0.3571331887893831 205 Q9BZG1,P33897,P61026,O43707,Q9H267,Q8N1B4,Q93050,P09601,P50570,Q9H7Z7,Q02790,Q9Y3A3,P05067,P51572,P16278,P55327,P46934,Q9H0U4,Q01105,Q9UNS2,Q9UBB4,O60499,Q9HD47,P27105,Q06787,O15400,Q9NQX7,Q86UE4,O75503,O95684,Q8N4A0,O15118,Q9UIQ6,Q99538,P02786,O95295,P51114,Q8IZ07,O75312,Q92905,O75569,P11717,Q07065,P11279,Q9Y487,P26572,P42892,Q12846,Q04656,O43752,Q10472,O75935,Q9H2J4,O00429,Q99584,Q6NTF9,Q99627,Q96A49 58 +Mitochondria associated endoplasmic reticulum membrane 0.6027571974172375 1.823157485727252 0.0682795420555595 1.0 0.3736976134058767 11 Q96N66,Q15388,P27824,Q13637,Q9Y320,P51572,Q96S66 7 +Intrinsic component of presynaptic membrane 0.7739313400922261 1.793363161676399 0.0729148739571456 1.0 0.3786601977092679 5 Q92542,P23634,P20020 3 +Plasma membrane region 0.2909168310949536 1.7724558183029293 0.076318923137407 1.0 0.3896955069697768 206 Q96D71,Q8WXH0,Q9BZG1,P06756,P36543,P09601,P50570,P53985,Q9Y6M7,P11233,O75787,Q01082,P04083,Q8TAD4,P05067,O95721,O43815,O15439,P23634,P05023,P52292,P55011,P46934,O15020,P98164,Q07954,Q15043,P20020,Q9HD47,P22413,Q8WTV0,P05026,Q06787,Q86UE4,Q9H4M9,O75955,Q15375,P02786,P15291,P57105,Q9BTU6,Q96J42,Q92542,Q16625,Q12846,Q04656,Q6P4Q7,Q13586,P30825,O75935,Q99720,O00429,Q06481,P27824,P51790,Q9NV96,Q8NCG7,P08183,P40855,Q96A49,P33527,P09493,P35613 63 +Caveola 0.5140147082887984 1.751691338116821 0.0798268971170479 1.0 0.3986982730326875 16 P09601,Q8WTV0,Q9HD47 3 +Platelet alpha granule 0.4915765166654574 1.7415495053244017 0.0815873035631897 1.0 0.4024696238412391 19 Q9H267,Q8NBM8,O43707,Q8NBX0,Q96JJ7,Q6UXV4,Q9NUQ9,P05067,Q06481,Q9Y6I9 10 +Phagocytic vesicle 0.4158930859600891 1.7397495261032672 0.0819030087904491 1.0 0.4024696238412391 48 Q9BZG1,P06756,P61026,Q93050,P13473,Q13637,P04439,P10321,Q03518,Q86Y82,P11279,Q9Y487,P42345,P08670,Q12846,Q04656,O43752,P51790,P01889,O14964,Q06481 21 +Postsynaptic specialization membrane 0.5638478738569174 1.733413936560503 0.0830221222685425 1.0 0.4029592200689113 12 Q99720,P57105,P52292 3 +Autophagosome 0.4246676404269318 1.729240057390174 0.0837661398392703 1.0 0.4029592200689113 31 Q9Y371,Q9HD42,Q8WUX9,Q8TBX8,P13473,Q96A57,Q9UQN3,O75787,P04844,Q9Y3E7,P11279,Q969Q5,O95721,Q9NRR5,Q9P253,Q9Y6I9 16 +Transporter complex 0.4254048415832075 1.702101458146069 0.0887363506330567 1.0 0.4113083232174194 67 Q9UDW1,O75381,Q86Y39,O14949,O43676,Q9C0H2,Q9BPX6,Q86WC4,Q9Y5J6,O95139,Q8IYU8,Q9Y5J9,Q9Y5L4,P62942,Q96CU9,P03886,O96000,O60220,Q9NWR8,Q9P0J0,Q9NV96,Q96S66 22 +Vacuolar proton transporting v type atpase v0 domain 0.8049368719295193 1.7002764719751855 0.0890789338684308 1.0 0.4113083232174194 4 Q9Y487,Q93050 2 +Proton transporting v type atpase v0 domain 0.8049368719295193 1.7002764719751855 0.0890789338684308 1.0 0.4113083232174194 4 Q9Y487,Q93050 2 +Nuclear pore nuclear basket 0.606915191997723 1.6991334656464836 0.0892940391221215 1.0 0.4113083232174194 9 Q8NFH5,Q9Y6D9,P41208 3 +Protein lipid complex 0.7522512385256723 1.696798572118305 0.0897347488059379 1.0 0.4113083232174194 5 Q9UHG3 1 +Golgi medial cisterna 0.8037862701596085 1.695388103141562 0.0900018212729583 1.0 0.4113083232174194 4 P04439,O95249 2 +Extrinsic component of mitochondrial inner membrane 0.7004136236833911 1.6799493398338885 0.092967172818742 1.0 0.4206534453283673 6 P49748,Q96D53,Q5HYK3,Q8NI60 4 +Clathrin coated endocytic vesicle membrane 0.5008962084408967 1.6586737194023582 0.0971815578779633 1.0 0.4297242202109433 16 P02786,O43493,P98164,Q14108 4 +Vesicle tethering complex 0.4277280138152591 1.6579742566023006 0.0973226625641852 1.0 0.4297242202109433 26 Q8WTW3,Q96JB2,Q9H267,Q8N1B4,Q6NUQ1,Q9UPT5,Q96A65,Q9UP83,Q96KP1,Q9P253,Q9UID3 11 +Atpase dependent transmembrane transport complex 0.6929684976392746 1.6444623404747063 0.1000807371394301 1.0 0.4327318262153843 6 Q9NP58,Q9NUT2,O14678,P05023 4 +Intrinsic component of peroxisomal membrane 0.6399664090892451 1.640773184905801 0.1008445065469112 1.0 0.4327318262153843 7 P33897,Q9Y3D6,Q96K12,O43808,P56589 5 +Rough endoplasmic reticulum 0.4015158724344847 1.6365340078140098 0.1017278742617495 1.0 0.4342144964232997 36 Q8TCT9,P61106,P49458,Q5BJF2,P51571,Q96A33,Q9UQB8,Q9Y5M8,P27824,P04844,P04843,Q07065,Q9HD47,P30533,P05067,Q99442,Q5VV42,Q9H9S5 18 +Recycling endosome 0.4051006963537404 1.6345654685753055 0.1021401714781284 1.0 0.4342144964232997 47 Q9H267,P61026,Q8N1B4,Q9UNK0,Q9H223,P04439,P05067,Q9UGJ1,Q9P260,O14828,P10321,O15400,Q9H4M9,O14773,Q86Y82,Q9UID3,P02786,P61106,Q9Y4I1,Q9UNF0,Q96A57,P51790,P01889,O15127 24 +Plasma membrane raft 0.4356406539410635 1.6274342837820517 0.1036448951247082 1.0 0.438571454370293 24 Q13586,P09601,Q8WTV0,Q9HD47 4 +Triglyceride rich plasma lipoprotein particle 0.9306456160135276 1.6168356483576132 0.1059137621925283 1.0 0.4440604524952794 2 Q9UHG3 1 +Presynaptic active zone membrane 0.7324410857169772 1.607948146344901 0.1078465358873959 1.0 0.4460749524625035 5 P20020,P23634,P27824 3 +Emc complex 0.6336226206970366 1.6078940479104442 0.1078583856610648 1.0 0.4460749524625035 7 Q8N4V1,Q9P0I2,Q9NPA0,Q15006,Q5J8M3 5 +Endosome membrane 0.353780367853017 1.5968341957951675 0.1103026712120929 1.0 0.4520925627257978 153 Q9H267,P61026,Q8N1B4,Q93050,Q9UH99,O14653,P13473,Q8N4V1,O75787,Q9NP58,P04439,Q9BRG1,Q14849,Q9HC07,Q9HD42,Q5T9L3,Q15043,P55899,P10321,O15400,Q86YV9,O15118,Q86Y82,Q8IV08,P02786,Q96RL7,P11717,P11279,Q8TCT8,Q9Y487,P61020,Q9P0T7,Q7Z6M1,P42892,Q92542,Q99805,Q04656,O00461,Q06481,P51790,P01889,Q15904,Q96L92,Q9Y3E7,Q14108,O14964,Q9NV96,Q9Y287,O15127,P51797,Q99758,O95772 52 +Glial cell projection 0.7746433174949556 1.5710619780677804 0.1161682532277912 1.0 0.4717998506093099 4 P05067 1 +Smooth endoplasmic reticulum 0.5598237309654903 1.568905084997833 0.1166700568529996 1.0 0.4717998506093099 11 P05067,O00264,Q86TM6,P27824 4 +Sarcoplasmic reticulum membrane 0.5821510031709397 1.560001081840402 0.1187596255351306 1.0 0.4760802532417079 9 Q13586,P16615,P62942 3 +Uniplex complex 0.7659348686898853 1.53373795304375 0.1250941327976442 1.0 0.4924078820875232 4 Q8IYU8,Q9BPX6 2 +Magnesium dependent protein serine threonine phosphatase complex 0.5848760720368815 1.5232822786369808 0.1276880988109412 1.0 0.4977538049839574 8 P30153,P30154 2 +Derlin 1 retrotranslocation complex 0.7128600224150818 1.5196136690350532 0.1286081004304051 1.0 0.4980839143787725 5 Q9BUN8,Q9UBV2 2 +Gpi anchor transamidase complex 0.7097443237832339 1.5055161875700018 0.1321914182711694 1.0 0.5034289845827036 5 O43292,Q9H490 2 +Coated vesicle membrane 0.4040180647483573 1.4992014989623628 0.1338213663056371 1.0 0.5075216962794702 61 Q8N511,P02786,O43493,P24390,O14653,P98164,P49755,P01889,P10321,Q9NR31,P04439,Q15363,Q14108,O43731,P49257,Q13190 16 +Cytoplasmic ubiquitin ligase complex 0.5450321416947924 1.4802055796138236 0.1388183918559624 1.0 0.5085939567231649 11 Q9GZP9,Q13438,Q9BUN8,Q86TM6,Q9UBV2 5 +Calcium channel complex 0.5679571176470241 1.47963967863615 0.1389694314902243 1.0 0.5085939567231649 9 Q8IYU8,Q9BPX6,P62942 3 +Ubiquinone biosynthesis complex 0.8970961375810553 1.4769107256952554 0.1396995694519551 1.0 0.5087067987214622 2 O75208 1 +Blood microparticle 0.4752109531221306 1.474717724640401 0.1402884487873974 1.0 0.5088239769511161 16 Q08380,P04062,O00560,P27105,P38435 5 +Platelet alpha granule membrane 0.7500808177640391 1.4656172253688855 0.1427525958534656 1.0 0.5150992019556967 4 Q96JJ7 1 +Coated vesicle 0.4031397831186603 1.4459764392768462 0.1481838102628878 1.0 0.5223342954530269 101 Q9H267,Q12907,P24390,O14653,Q96RQ1,Q969X5,Q15363,P04439,P05067,P51572,Q8N511,Q9BXS5,P98164,P10321,P02786,Q5VYK3,Q5VW38,P49755,P11717,Q9NR31,O43731,P49257,Q9Y3A6,P42892,Q13190,O43493,Q04656,Q9Y282,O43752,O95070,Q969M3,P01889,Q14108 33 +Intrinsic component of presynaptic active zone membrane 0.7437759830276347 1.4384737040598583 0.1502996933305755 1.0 0.5223342954530269 4 P20020,P23634 2 +Integral component of presynaptic active zone membrane 0.7437759830276347 1.4384737040598583 0.1502996933305755 1.0 0.5223342954530269 4 P20020,P23634 2 +Acrosomal membrane 0.7414293378804918 1.4283642126090463 0.1531870542658038 1.0 0.5244452397681787 4 Q15643,P35613 2 +Microtubule organizing center attachment site 0.7412844012355826 1.4277397036952069 0.1533667936740017 1.0 0.5244452397681787 4 Q8WXH0,Q9UH99 2 +Dendrite membrane 0.7396332863187761 1.4206244122391618 0.1554259775831385 1.0 0.5244452397681787 4 P20020,P23634,O75787 3 +Apicolateral plasma membrane 0.6423355466067165 1.400864366041362 0.1612546363750324 1.0 0.5334841476918097 6 P46934 1 +Postsynaptic density membrane 0.5625854834692386 1.3994451011048086 0.16167955023045 1.0 0.5334841476918097 8 P23634,Q99720,P57105 3 +Proteasome core complex beta subunit complex 0.5898327010304312 1.3789785529454517 0.1679013665867532 1.0 0.5443774238442597 7 P49721,P28070,P28072 3 +Tim22 mitochondrial import inner membrane insertion complex 0.8809926677946996 1.3756645409785806 0.1689255148105863 1.0 0.5452171153505935 3 Q9Y584,Q9Y5J6 2 +Mitochondrial crista 0.8805930257311382 1.3740988146697437 0.1694110073955892 1.0 0.5452171153505935 3 O60313 1 +Gamma secretase complex 0.870312940513112 1.3651422495040613 0.172208345184972 1.0 0.5503441520946311 2 Q92542 1 +Azurophil granule lumen 0.3766110085116355 1.3609233177466171 0.1735379237942682 1.0 0.5526608444179832 44 P08236,P17900,P61916,O00754,O00584,O43681,O00560,Q9H7Z7,P78371,Q9BTY2,P07686,Q96CS3,Q92820,P06280,Q13217,P15586,P16278,P10619 18 +Presynaptic membrane 0.4349628236578702 1.3497596683486963 0.177093085761117 1.0 0.5592998635863579 20 Q92542,Q12846,P27824,P20020,Q9BTU6,Q06787,P23634 7 +Side of membrane 0.3967729789493054 1.3326894152525843 0.1826337482395401 1.0 0.5677797479283664 80 Q8TCT9,P06756,O96005,O75787,P04083,P04439,P51572,O15439,Q08431,P07237,P17900,P98164,P49327,P55899,P20020,P10321,O75955,P62942,P02786,P15291,P11279,Q8TCT8,P42892,A0FGR8,P10619,Q9NR28,P27824,P51790,P01889,P08183,Q96A49 31 +Mitochondrial permeability transition pore complex 0.708662343637968 1.2869318755524906 0.1981180339025732 1.0 0.6096965757136429 4 P12235,P21796 2 +Escrt iii complex 0.707475317348375 1.2818026457685323 0.1999118858570667 1.0 0.6111058477715067 4 Q9Y3E7,Q9HD42,Q8WUX9 3 +Ficolin 1 rich granule membrane 0.4317048560679142 1.2782514459456684 0.2011607817663661 1.0 0.6111058477715067 19 Q93050,P10253,P13473,P11279,Q5T9A4,P42785 6 +Dendritic spine membrane 0.8513818386914799 1.259714142354201 0.2077725017666909 1.0 0.620600606597658 3 P20020,P23634 2 +Secondary lysosome 0.85091760014482 1.257898192799705 0.2084285773654595 1.0 0.620600606597658 3 P11279 1 +Autolysosome 0.85091760014482 1.257898192799705 0.2084285773654595 1.0 0.620600606597658 3 P11279 1 +Parallel fiber to purkinje cell synapse 0.8440936002255458 1.2559608009433516 0.2091301825296248 1.0 0.620600606597658 2 P23634 1 +Postsynaptic cytoskeleton 0.8440936002255444 1.2559608009433467 0.2091301825296265 1.0 0.620600606597658 2 P07196 1 +Cop9 signalosome 0.504552705621012 1.23544991063652 0.2166631072990612 1.0 0.6353350763829145 11 Q99627,Q9UNS2,Q92905,Q9BT78 4 +Sarcolemma 0.3915409893624711 1.2348781176887658 0.2168758685245835 1.0 0.6353350763829145 24 Q92542,P04083,P05026,Q96QD8,P11279,P23634,O75955,P35613,Q9H9S5,P05023 10 +Golgi trans cisterna 0.8370453904708198 1.2266911142442205 0.2199387087105657 1.0 0.638171364322086 2 Q96CN9 1 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.6468342797715962 1.2192134398494017 0.2227631921651018 1.0 0.6390952568895397 5 O75964,P24539 2 +Endocytic vesicle 0.3858938396490149 1.2042742525650716 0.2284835948789247 1.0 0.6485528127929728 94 Q9BZG1,P06756,P61026,Q93050,P50570,Q5KU26,P13473,P11233,Q13637,P04439,Q5T9L3,P07900,P98164,Q07954,P10321,Q03518,Q8WTV0,O15400,Q86Y82,P02786,Q5VYK3,P11717,P11279,Q969Q5,Q9Y487,P61020,P42345,P08670,O43493,Q16625,Q12846,Q04656,O00461,O43752,P51790,P01889,Q14108,O14964,Q06481 39 +Intrinsic component of vacuolar membrane 0.8346065411685217 1.1941644511198315 0.2324136457875796 1.0 0.649048855165215 3 O15118 1 +Platelet alpha granule lumen 0.4742809056038267 1.168311939701583 0.242680960986831 1.0 0.6641029890477951 12 Q8NBM8,O43707,Q8NBX0,Q6UXV4,Q9NUQ9,P05067,Q9Y6I9 7 +Neurofilament 0.8274111675126815 1.1661038003723965 0.2435724803193315 1.0 0.6641596455082277 3 P07196,P07197 2 +Mhc protein complex 0.8245910885504737 1.1551173010750495 0.2480423942330043 1.0 0.66746180468735 3 P10321,P04439 2 +Mhc class i protein complex 0.8245910885504737 1.1551173010750495 0.2480423942330043 1.0 0.66746180468735 3 P10321,P04439 2 +Chitosome 0.6776523511646937 1.152985031965436 0.2489165282173615 1.0 0.66746180468735 4 Q13637,Q9NP58 2 +Cell surface 0.3818916928854292 1.1490410144037275 0.2505390689231839 1.0 0.66746180468735 86 Q8TCT9,P06756,Q12907,P11233,O75787,O96005,O15258,P04083,P04439,P05067,Q92859,O15439,Q08431,P07237,P98164,P49327,P55899,P10321,P22413,Q8WTV0,Q07021,O75955,P06576,P02786,P15291,O15031,Q99623,P11717,P11279,Q9UII2,P42892,Q08722,Q12846,Q96JJ7,P01889,P51790,P08183 37 +Gap junction 0.6306674753638801 1.1454413496629752 0.252026377804049 1.0 0.66746180468735 5 Q07157,Q96RD7 2 +Haus complex 0.5892275366289244 1.142701908819491 0.2531623770146223 1.0 0.66746180468735 6 O94927,Q96CS2 2 +Intermediate filament 0.4142210455354922 1.141243982104326 0.2537684062436121 1.0 0.66746180468735 19 P07196,Q03252,Q16352,P07197,P02545,P20700,P08670 7 +Early endosome lumen 0.8153369044262756 1.1368700961765774 0.2555925947927489 1.0 0.66746180468735 2 Q9UIQ6 1 +Specific granule 0.3504072045865899 1.1273245621654922 0.2596052811740903 1.0 0.6721791132949534 40 Q08722,Q9BXS5,P06756,Q12846,O00264,P51790,Q07065,Q9NV96,P27105,P30519 10 +Platelet dense granule membrane 0.8119537637440153 1.1229271475707554 0.2614684366506385 1.0 0.6724523552569931 2 P13473 1 +External side of apical plasma membrane 0.8119537637440087 1.1229271475707292 0.2614684366506496 1.0 0.6724523552569931 2 P08183 1 +Platelet dense granule 0.8121827411167424 1.1068657140732348 0.2683519913973176 1.0 0.6756851794411798 3 P13473,Q08380 2 +Oxidoreductase complex 0.367715001713366 1.1009611474409784 0.2709135671323421 1.0 0.6757910570862297 60 O43169,O95139,P07237,Q9UDW1,Q96CU9,Q86Y39,P03886,O14949,Q15118,Q9P0J0,P21912,O43676,O96000 13 +Sperm midpiece 0.6645149617440813 1.0963601609655131 0.2729211911560951 1.0 0.6757910570862297 4 Q96RL7 1 +Growth cone membrane 0.8054694107696585 1.0962529208913967 0.272968106023906 1.0 0.6757910570862297 2 Q9UPT5 1 +Nuclear envelope lumen 0.6198446597376355 1.0961087953191886 0.273031166068387 1.0 0.6757910570862297 5 P11717,P05067 2 +Membrane microdomain 0.3737039395948344 1.0958978563184514 0.2731234773164517 1.0 0.6757910570862297 71 P09601,P13473,P50897,P05067,P23634,P05023,P49327,P20020,P30154,Q8WTV0,P27105,P05026,O94905,Q9HD47,O15118,O14773,O75955,Q86Y82,P05141,Q9BTU6,P21796,Q9UJZ1,P46108,Q04656,Q13586,O00560,P35613 27 +Zymogen granule membrane 0.803775458372138 1.0742691406023914 0.2827020718110782 1.0 0.6883782966002179 3 Q15363 1 +Endoplasmic reticulum plasma membrane contact site 0.79362841838173 1.0477329054002895 0.2947616825675603 1.0 0.7052674813265709 2 Q9NTJ5 1 +Borc complex 0.7885537073583306 1.0270228177666585 0.3044097198195215 1.0 0.7194347459102142 2 O95295 1 +Bloc 1 complex 0.7885537073583306 1.0270228177666585 0.3044097198195215 1.0 0.7194347459102142 2 O95295 1 +Zymogen granule 0.6482743320977962 1.0265796683587711 0.304618431802246 1.0 0.7194347459102142 4 Q15363 1 +Bloc complex 0.7887760857303975 1.0163523257587337 0.3094616393887759 1.0 0.7240161413741756 3 O95295,Q86YV9 2 +External encapsulating structure 0.3494930756566615 1.0078840399129405 0.3135101344445492 1.0 0.7240161413741756 32 Q92896,Q08380,Q53GQ0,Q5KU26,Q9NZJ7,Q32P28,P52272,P04083,P49257,P07602,Q08431 11 +Anchored component of synaptic vesicle membrane 0.6004013155182983 1.0077246869172032 0.3135866501232622 1.0 0.7240161413741756 5 P61020,P51149,P20339 3 +Integral component of cytoplasmic side of endoplasmic reticulum membrane 0.7837609247251025 1.0075146554559042 0.3136875185822467 1.0 0.7240161413741756 2 Q8TCT8 1 +Atp binding cassette abc transporter complex 0.7805978567399848 0.9849259450811554 0.3246604480684338 1.0 0.7318894918017075 3 Q9NP58,O14678 2 +Amphisome 0.5565364115247259 0.9839315223162396 0.3251491834071158 1.0 0.7318894918017075 6 Q9HD42,Q9Y3E7,Q8WUX9 3 +Exocyst 0.5148131462195933 0.9830263462664872 0.3255944720439645 1.0 0.7318894918017075 7 Q96A65,Q9UPT5 2 +Lamellar body 0.7788847610665273 0.9783583871795896 0.3278971017110819 1.0 0.7318894918017075 3 Q07065 1 +Ciliary transition zone 0.4777794876123387 0.9699561278084622 0.3320683609189858 1.0 0.7384683257419783 10 Q15154,Q15051,P41208,A6NIH7 4 +Amphisome membrane 0.5911147860013959 0.96567964709921 0.3342045069270898 1.0 0.7391379184669455 5 Q9HD42,Q9Y3E7,Q8WUX9 3 +Cell body membrane 0.7755217146079976 0.9654817800031332 0.3343035575600501 1.0 0.7391379184669455 3 P20020,P23634 2 +Tertiary granule membrane 0.4408663895707971 0.9556920890415824 0.339227820461228 1.0 0.7435353187087828 12 Q08722,P10253,P27105 3 +Platelet dense tubular network 0.7676910064843552 0.9425140457705614 0.3459295234350303 1.0 0.7528085343324232 2 P16615 1 +Platelet dense tubular network membrane 0.7676910064843552 0.9425140457705614 0.3459295234350303 1.0 0.7528085343324232 2 P16615 1 +Protein phosphatase type 2a complex 0.5461431642684895 0.9337249638576636 0.3504457843402835 1.0 0.7574663318482692 6 P30154 1 +Ciliary basal body 0.3576299518266509 0.9306585082550246 0.3520302389406984 1.0 0.7588576377165055 24 Q15154,Q9Y366,Q9UPT5,P48729,P28070,P41208,Q8IUD2,Q15691,A0AVF1 9 +Rough endoplasmic reticulum membrane 0.4044281287653772 0.9227520121427724 0.3561364539182265 1.0 0.7625362835803738 15 P51571,Q96A33,Q9Y5M8,P49458 4 +Endoplasmic reticulum quality control compartment 0.5414391442044798 0.911069124795412 0.3622589532303677 1.0 0.7625362835803738 6 Q86TM6,Q9BUN8 2 +Transcription factor tfiid complex 0.4745936485176342 0.9073234876428544 0.3642357570760199 1.0 0.7625362835803738 8 Q15545,P29083,Q9Y6J9,P18074 4 +Epsilon dna polymerase complex 0.6202360062412084 0.907040578495686 0.3643853390909957 1.0 0.7625362835803738 4 Q9NR33 1 +Endoplasmic reticulum exit site 0.3736450319966625 0.9024009083939848 0.3668439387356212 1.0 0.7625362835803738 21 Q96PC5,Q5JRA6,Q9NR31,P04439,Q9Y3A6 5 +Neuron projection membrane 0.4495081997770218 0.9019743426596514 0.3670704973897947 1.0 0.7625362835803738 11 Q12846,Q9HBM0,P20020,Q01082,O75787,P23634,Q14168 7 +Presynapse 0.3592885326505483 0.8828782034790401 0.3773020813739582 1.0 0.7719142431882685 98 P51116,P61026,P50897,O76024,P05067,Q9BT78,O95721,P23634,P07196,O15020,O60499,P20020,Q06787,O15400,Q07021,O75955,Q86Y82,O95295,Q7L0J3,P51114,Q99623,Q96A57,Q92905,O43760,Q9BTU6,P11279,P61020,Q9UI14,Q92542,Q12846,O43752,O00429,P27824,P51790,Q96A49,O75150 36 +Centriolar satellite 0.3521217801471107 0.8815095527001113 0.3780420859066484 1.0 0.7719142431882685 24 Q15154,Q9UPT5,Q13045,Q03518,Q14498,O75955 6 +Sarcoplasm 0.3845046200170068 0.8798520485057229 0.3789394642297272 1.0 0.7719142431882685 18 P16615,P52789,Q13586,O43852,P62942 5 +Glycoprotein complex 0.7519030166337735 0.8793698748304501 0.3792007606034273 1.0 0.7719142431882685 2 Q13425 1 +Dystrophin associated glycoprotein complex 0.7519030166337735 0.8793698748304501 0.3792007606034273 1.0 0.7719142431882685 2 Q13425 1 +Signal peptidase complex 0.7475924739164541 0.8595197004548477 0.3900538558187354 1.0 0.7864753988286247 3 P67812 1 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.6087187025313717 0.8584278217568654 0.3906562703153124 1.0 0.7864753988286247 4 P21953 1 +Postsynaptic density intracellular component 0.603102961918198 0.8348568792053114 0.4037982959901636 1.0 0.7985093157474831 4 Q9UQB8,P50570,O60716 3 +Postsynaptic specialization intracellular component 0.603102961918198 0.8348568792053114 0.4037982959901636 1.0 0.7985093157474831 4 Q9UQB8,P50570,O60716 3 +Spectrin 0.5577845764775886 0.816259733357319 0.4143515992866398 1.0 0.8095054005281778 5 Q01082,O15020 2 +Neuronal ribonucleoprotein granule 0.7359627381304688 0.8160087930648725 0.4144951066161786 1.0 0.8095054005281778 3 Q06787 1 +Ciliary rootlet 0.7318861009303426 0.8005586231700401 0.4233872126666551 1.0 0.8181308929753125 2 P05067 1 +Presynaptic cytoskeleton 0.7307583873695873 0.7961658343599709 0.425935652957246 1.0 0.8213189594998371 2 P07196 1 +Intraciliary transport particle 0.5915950504823668 0.7868670845758969 0.4313596776775517 1.0 0.8245352563298208 4 Q9Y366,A0AVF1 2 +Hops complex 0.5497943258893863 0.780913267919043 0.4348535079811491 1.0 0.8245352563298208 5 Q9H267,Q9P253 2 +Endoplasmic reticulum tubular network membrane 0.7252470952912624 0.7763015145684433 0.4375709790252435 1.0 0.8245352563298208 3 Q9NQC3 1 +Bleb 0.5128913366303036 0.774848762857302 0.4384290312650907 1.0 0.8245352563298208 6 Q9BRK5,Q96RD7 2 +Golgi transport complex 0.5458843221506996 0.7637016141207382 0.4450450786676427 1.0 0.8277008507623607 5 Q8WTW3,Q96JB2,Q9UP83 3 +Microbody 0.3395278145835346 0.7532915746641698 0.4512747206272198 1.0 0.8312262814896771 64 P33897,O75381,Q6YN16,O14678,P51648,O43808,Q9NR77,Q96CN7,Q9UKU0,Q8N4Q0,P04035,Q9NP80,P08670,Q9Y3D6,O00429,Q15067,Q9BY49,Q9BQG2,P40855,Q2T9J0 20 +Chromocenter 0.5422073732277692 0.7475709833304052 0.4547189723685323 1.0 0.8312262814896771 5 Q06787,P45973 2 +Cytoplasmic microtubule 0.342739094921875 0.7432880385084425 0.4573073118555077 1.0 0.8342891876964752 23 Q6NUK4,Q9BRK0,Q9Y5M8,Q6NUQ4,Q9H6H4 5 +Cell tip 0.7146884691288333 0.7341897932529315 0.4628330732866614 1.0 0.836661565696389 2 Q9BTU6 1 +Nucleotide activated protein kinase complex 0.5310171640892524 0.6988401442428892 0.4846519374529126 1.0 0.858444194679285 5 P54619 1 +Dendrite terminus 0.5673019444153641 0.6872319363855871 0.4919365822086206 1.0 0.8639479401688174 4 Q9Y366,P07900 2 +Anaphase promoting complex 0.3854638009049793 0.6804041402932226 0.4962486001718429 1.0 0.8639479401688174 13 Q12834,Q16763,Q14999,Q9UJX2,Q96DE5,Q9UJX4,Q9UJX5,P30260,Q9UJX3,Q9H1A4,O60566,Q13042 12 +Neuron spine 0.3102548568620549 0.6803226048851825 0.4963002144771244 1.0 0.8639479401688174 36 P51116,P46934,P51114,P27824,P20020,O75787,Q06787,P05067,P23634 9 +Early endosome 0.3338469084073991 0.6724985600661323 0.5012663565052629 1.0 0.8639479401688174 120 Q9H267,Q8N4V1,Q13637,Q9NP58,P04439,P05067,Q9HC07,Q9HD42,Q5T9L3,P62820,Q13510,Q07954,Q9BUN8,Q15043,P10321,O15400,Q86YV9,O75955,Q86Y82,Q9UIQ6,Q8IV08,P02786,Q5VYK3,Q5VW38,Q96A57,P11717,P61020,Q92542,Q9GZP9,Q04656,O43752,Q92544,P51790,P01889,Q96L92,Q9NV96,O14964,Q06481,Q12768 39 +Fhf complex 0.696363123766545 0.6651036704999588 0.5059841871490462 1.0 0.8662519437550092 2 Q96ED9 1 +Cohesin complex 0.5223519171207742 0.6615202900972018 0.5082787068881354 1.0 0.8683490431696368 5 Q8N3U4,Q8WVM7 2 +Escrt complex 0.4228225504407534 0.6582221050358097 0.51039542267118 1.0 0.8696138767311886 10 Q9HD42,Q8WUX9,Q92783,Q9Y3E7,Q9BRG1,O14964 6 +Cell pole 0.6878172588832581 0.6411551932048775 0.5214218576702132 1.0 0.8751348143713382 3 Q9BTU6,P35241 2 +Compact myelin 0.6858432036096838 0.6342069208939675 0.5259457914870476 1.0 0.8751348143713382 3 Q9NR77,Q8N3R9 2 +Postsynaptic recycling endosome 0.6870594868903263 0.6307677499754405 0.5281923930708805 1.0 0.8751348143713382 2 Q86Y82 1 +Cation transporting atpase complex 0.6841511562323658 0.6282673768641401 0.5298287989078498 1.0 0.8751348143713382 3 P05026,P05023 2 +Sodium potassium exchanging atpase complex 0.6841511562323658 0.6282673768641401 0.5298287989078498 1.0 0.8751348143713382 3 P05026,P05023 2 +Schmidt lanterman incisure 0.6856498449393886 0.6256124550553716 0.5315691673578617 1.0 0.8751348143713382 2 Q8N3R9 1 +Paranodal junction 0.6856498449393789 0.6256124550553347 0.531569167357886 1.0 0.8751348143713382 2 O15020 1 +Mitotic spindle microtubule 0.4137971060730321 0.6070717284149799 0.5438033113508174 1.0 0.8802171447301608 9 O94927,Q96CS2 2 +Messenger ribonucleoprotein complex 0.4764007482154232 0.6056793137676514 0.5447277231434176 1.0 0.8802171447301608 6 Q06787 1 +Transcription factor tfiih holo complex 0.5432086338872499 0.5912905252936744 0.5543257768247252 1.0 0.8841624562221715 4 Q96T76,P18074 2 +Cell trailing edge 0.473045441716035 0.5905171020395859 0.5548440235428584 1.0 0.8841624562221715 6 Q14254,P41440,P15311,P26038,O75955 5 +Potassium channel complex 0.674372709331837 0.5848442568902614 0.5586524429944015 1.0 0.8841624562221715 2 Q9NUT2 1 +Striated muscle thin filament 0.5040570461370257 0.5841324840752374 0.5591311812871063 1.0 0.8841624562221715 5 P09493,P67936 2 +Myofilament 0.5040570461370257 0.5841324840752374 0.5591311812871063 1.0 0.8841624562221715 5 P09493,P67936 2 +Alveolar lamellar body 0.6721172822103063 0.5767958836030227 0.5640773506471708 1.0 0.8870933280048616 2 Q99758 1 +Aryl hydrocarbon receptor complex 0.6718353538201332 0.5757923942871979 0.5647555150043693 1.0 0.8870933280048616 2 O00170 1 +Equatorial microtubule organizing center 0.6640298836046461 0.5588560009649377 0.5762599996367266 1.0 0.9003446831931079 3 Q9UGJ1 1 +Lateral plasma membrane 0.3199708166728187 0.5524905308017606 0.5806123202944629 1.0 0.9055966906981896 23 P30153,Q8TAA9,P53985,P55011,P04083,Q86VI3,P33527,P05023 8 +9plus0 non motile cilium 0.347236401887367 0.530835823023651 0.5955325534686753 1.0 0.9148180737317128 15 P41208 1 +Ragulator complex 0.6549196504088022 0.5166757441616704 0.6053825310764092 1.0 0.9221993890063966 2 Q6IAA8 1 +Mmxd complex 0.6474901297236338 0.5036678591634819 0.6144947979189621 1.0 0.9249952695455256 3 Q96T76,P05141 2 +Mhc class i peptide loading complex 0.5182402191318278 0.4958146174341166 0.6200252107872537 1.0 0.925985363822794 4 Q03518 1 +Acrosomal vesicle 0.3114957641792214 0.4836963934220321 0.628601353155066 1.0 0.9315901128888712 23 O95295,P45880,O60271,Q15643,P07686,Q9H0H5,Q9Y487,P35613,Q08431 9 +Paraspeckles 0.4465288076028134 0.4738030299747844 0.6356403737051914 1.0 0.9342984789347676 6 P52272,Q8WXF1,P23246 3 +Dendritic shaft 0.4448167144909761 0.4664823984189 0.6408702437223839 1.0 0.937380995337708 6 P05067,Q14168 2 +Early endosome membrane 0.3072970572061376 0.4648378568864645 0.6420475753244164 1.0 0.937380995337708 57 Q9H267,Q8N4V1,Q9NP58,P04083,P04439,Q9HC07,Q5T9L3,Q15043,P10321,O15400,Q86YV9,Q86Y82,Q8IV08,P61020,Q04656,P51790,P01889,Q96L92,Q9NV96,O14964,Q06481 21 +Postsynaptic membrane 0.2928399900230031 0.4645708461231425 0.6422388140553079 1.0 0.937380995337708 33 P57105,P50570,Q99720,P27824,P51790,O75787,Q8NCG7,Q06787,Q96A49,P23634,Q15375,P52292 12 +Postsynaptic endosome 0.6336717428088048 0.4590259985880039 0.6462154963308806 1.0 0.937380995337708 3 Q86Y82,P20338 2 +Wash complex 0.4686086233968138 0.4411375016246025 0.6591134556010223 1.0 0.9424347877340884 5 Q9Y3C0 1 +Carboxy terminal domain protein kinase complex 0.4340953993790413 0.421324814819837 0.673517912381628 1.0 0.94399001904798 6 P19447,P18074,Q96T76,Q9NYV4,P32780 5 +Neuromuscular junction 0.3183964746528454 0.4148146034486141 0.6782776282436278 1.0 0.94399001904798 19 P07196,Q7L0J3,P57105,O43760,P46939,P05067,Q15375,P10644 8 +Pam complex tim23 associated import motor 0.6239075274880248 0.4145612254653857 0.6784631380955277 1.0 0.94399001904798 2 Q96DA6 1 +Tight junction 0.2911762326914603 0.4128611895060183 0.6797083173130232 1.0 0.94399001904798 28 Q9NR77,Q86UE4 2 +Endoplasmic reticulum chaperone complex 0.4006675745491557 0.4118504945148945 0.6804490082321044 1.0 0.94399001904798 7 P14625,P07237,Q9UBS4,Q8IXB1 4 +Immunological synapse 0.3405235885327656 0.4062681145108467 0.6845456109234112 1.0 0.94399001904798 13 P20020,Q96L92,O15400,Q9UJZ1 4 +Site of polarized growth 0.2958767986811015 0.3974507523004406 0.6910350959911005 1.0 0.94399001904798 52 P07196,P51116,P51114,P07900,O75312,Q13561,Q9UPT5,P50570,Q99720,Q96A49,Q9BTU6,Q02790,Q96A65,Q06787,P05067,Q92859,Q8N5V2 17 +Ciliary membrane 0.3970069358872879 0.395349815449307 0.692584740049236 1.0 0.94399001904798 7 Q96J42 1 +Intraciliary transport particle b 0.6103286574811986 0.3870406377081112 0.698726123374412 1.0 0.94399001904798 3 Q9Y366 1 +Basement membrane 0.6102650874224542 0.3868509554347814 0.698866551465156 1.0 0.94399001904798 3 Q03001,O14936 2 +Lsm2 8 complex 0.4529142990591921 0.3815487024572253 0.7027961399725913 1.0 0.944640694021983 5 Q9Y4Y9 1 +Mitotic spindle pole 0.3131781533466223 0.3788699005293886 0.7047844767277383 1.0 0.9455121733512164 19 Q9P287,Q8WVM7,Q96DB5,Q9Y6D9,Q14155,P53350 6 +Clathrin coated vesicle 0.2950230109769202 0.3681270821900969 0.7127784779872024 1.0 0.9465306541656106 54 P02786,Q9BXS5,O43493,Q9H267,Q04656,O43752,Q5VW38,P98164,P49755,P11717,Q14108,P51572,P42892 13 +Dendrite cytoplasm 0.3552315549921331 0.3671097503272715 0.7135371546014024 1.0 0.9465306541656106 11 Q9UQB8,P27824,P23246,Q8N2K0,P33176 5 +Dna polymerase complex 0.3331447963800926 0.3643539152800473 0.7155937440136071 1.0 0.9465306541656106 13 Q9NR33,P54098,P49643,P56282,Q9NRF9,Q14181,P28340,P09884,Q07864,Q9Y2S7,P49642,P49005 12 +Myelin sheath adaxonal region 0.5988195176679749 0.3533012748786481 0.723862589866358 1.0 0.9492258352049516 3 Q12846 1 +Rna polymerase ii transcription repressor complex 0.601071327882728 0.3453888510214621 0.7298020576754387 1.0 0.9521726720510604 2 P35222 1 +Collagen containing extracellular matrix 0.2825448122814818 0.339384409000577 0.7343201621920596 1.0 0.9534231747188484 28 Q08380,Q9NZJ7,Q32P28,P52272,P04083,P49257,P07602,Q08431 8 +Prefoldin complex 0.4384759924936845 0.329182993217176 0.7420173767080973 1.0 0.9534231747188484 5 Q9UHV9,O15212 2 +Clathrin coated vesicle membrane 0.2816196342633171 0.3276571033147971 0.7431709409373768 1.0 0.9534231747188484 26 O43493 1 +Nuclear pore central transport channel 0.4695906242091335 0.3255079596073175 0.7447966594630828 1.0 0.9534231747188484 4 Q7Z3B4 1 +Synaptic membrane 0.2838229520244059 0.3207522202165331 0.7483981703827363 1.0 0.9551659924542796 48 Q92542,P57105,Q12846,P50570,Q99720,P27824,P51790,P20020,O75787,Q9BTU6,Q8NCG7,Q06787,Q96A49,P23634,Q15375,P52292 16 +Photoreceptor connecting cilium 0.3599252119540924 0.3150704694083424 0.7527081494733621 1.0 0.9559026207173906 8 Q15051,P41208 2 +Dynactin complex 0.4336730802228933 0.3123360672783292 0.75478513236652 1.0 0.9559026207173906 5 O75935,Q13561,Q9UJW0 3 +Myosin ii complex 0.4645980253878566 0.309475649112167 0.7569597328005047 1.0 0.9559026207173906 4 P35579,P35580,P60660 3 +Intrinsic component of postsynaptic density membrane 0.5818706367610651 0.3059340992043646 0.7596548225009452 1.0 0.956369845407526 3 P23634 1 +Intrinsic component of postsynaptic specialization membrane 0.4617562659679136 0.3004866093405426 0.7638060089811705 1.0 0.9589542475395464 4 P23634 1 +9plus2 motile cilium 0.2869213390357011 0.2945684403512945 0.7683235738907612 1.0 0.9633028073198296 23 Q15388,Q96RL7,P41208 3 +Meiotic cohesin complex 0.4575458392101404 0.2873547441922824 0.7738407094322346 1.0 0.967873470008553 4 Q9UQE7,Q8N3U4,O60216 3 +Nuclear membrane 0.3077419636887853 0.2810883012273796 0.7786426738591801 1.0 0.9682712978330484 110 Q8WXH0,Q15154,Q8TEM1,Q9UH99,Q8N1F7,P02545,Q9BTX1,O15504,Q5JTV8,Q9P035,Q5SNT2,Q7Z3B4,Q5BJF2,Q6ZRP7,Q86UE4,Q8NFH5,Q9H1E5,Q9BW91,P50402,Q9BTV4,Q8IXM6,O14681,Q9H2V7,O75844,Q03252,Q99720,Q9H8M7,O00560,P20700,Q96KC8,Q14739,O94901,Q96S66 33 +Photoreceptor outer segment 0.3480326449220869 0.2630783424396505 0.7924901963742363 1.0 0.974880268487284 8 P35613,Q15051 2 +Excitatory synapse 0.391872332812776 0.2572928904258837 0.7969526803788594 1.0 0.977737919283594 6 P23634 1 +Nuclear outer membrane 0.3316597830386494 0.2524739026118132 0.8006747835556385 1.0 0.980987603444844 11 Q99720,P50402 2 +Phosphatidylinositol 3 kinase complex 0.5641387087679866 0.2461529512136575 0.8055638346193674 1.0 0.9813754498156406 2 O00443 1 +Mcrd mediated mrna stability complex 0.4126653386995737 0.2423521017500428 0.808507345417043 1.0 0.9813754498156406 5 Q14103,O60506 2 +Recycling endosome membrane 0.2692629588974786 0.231545611049372 0.8168909554969099 1.0 0.9850109938313664 25 P02786,P61106,P61026,O14828,Q9UNF0,Q9H223,P01889,P10321,P04439,O15127,Q9H4M9,Q86Y82 12 +Myelin sheath 0.3072493652682404 0.2271717297534 0.8202902094285056 1.0 0.9858495698486132 13 Q9NR77,Q96A65,P07900,Q12846 4 +Filopodium tip 0.4071670428893701 0.2251008176833638 0.82190084488473 1.0 0.9858495698486132 5 Q9Y4I1,Q7L576,Q06787,P61086 4 +Saga complex 0.3792133632758467 0.2132921141538628 0.831099124036162 1.0 0.9955761459620605 6 Q9Y6J9 1 +Brush border membrane 0.331134968504582 0.2044869742729941 0.8379729699706653 1.0 1.0 10 P98164,P15291,P40855 3 +Axonal growth cone 0.3736882684008555 0.1949521881963858 0.8454303776524987 1.0 1.0 6 Q02790,Q92859 2 +Intermediate filament cytoskeleton 0.2584005408891022 0.1806974866870047 0.8566050316468516 1.0 1.0 36 Q8WXH0,P07196,Q03252,Q16352,Q3SXM5,P07197,P02545,P20700,P08670 9 +U6 snrnp 0.3670300649302557 0.1735846390490381 0.862191905003435 1.0 1.0 6 Q9Y4Y9 1 +Centriole 0.2606912978990615 0.1688951743316765 0.8658790949959057 1.0 1.0 30 Q15154,Q9P287,P41208,Q14203,O95684,Q15051,P53350 7 +Axolemma 0.5234035229380369 0.1666200028082084 0.8676690537514147 1.0 1.0 3 Q01082 1 +Tubular endosome 0.414018341198661 0.1658884286611502 0.8682447539127378 1.0 1.0 4 Q9Y5X3,Q9UNH7 2 +Postsynaptic cytosol 0.3342744212309577 0.1467853550194656 0.8833014444690974 1.0 1.0 7 Q9UQB8,P11142,Q01970,Q16643,P38919,P42858 6 +T tubule 0.3332236844667204 0.1432827928715343 0.8860668449077387 1.0 1.0 7 P23634,P05026,P05023 3 +Non motile cilium 0.2732107303357052 0.1382213104552533 0.890065513441207 1.0 1.0 20 Q15154,P35613,Q15051,P41208 4 +Prespliceosome 0.302777674196989 0.1300739784242138 0.8965078974002243 1.0 1.0 11 Q15459,P08621,P09234,P26368,O75400,Q86UA1 6 +Dendritic growth cone 0.5010269966479922 0.1241898349985414 0.9011649704280084 1.0 1.0 3 P07900 1 +Transcription factor tftc complex 0.3926657263751599 0.1167753094394681 0.9070381100774634 1.0 1.0 4 O75528,Q15545,P49848 3 +Clathrin coated endocytic vesicle 0.2635096656786413 0.1143629101072405 0.908950114493611 1.0 1.0 22 P02786,O43493,P98164,P11717,Q14108 5 +Spindle pole centrosome 0.3232573880133425 0.1113214136987118 0.9113614752660476 1.0 1.0 7 P50402 1 +Dihydrolipoyl dehydrogenase complex 0.3457889064088085 0.1110875334549199 0.9115469344144076 1.0 1.0 6 P21953 1 +Proton transporting v type atpase v1 domain 0.3078234535524664 0.1101450225866177 0.9122943624901731 1.0 1.0 8 Q15904 1 +Sperm annulus 0.488719684151174 0.1035413771013523 0.9175333117705496 1.0 1.0 3 Q14141,Q15019 2 +Mitotic cohesin complex 0.4908373273188777 0.1022085477814035 0.9185911431416304 1.0 1.0 2 Q9UQE7 1 +Ap type membrane coat adaptor complex 0.2855527283008156 0.100854058594783 0.9196663130121112 1.0 1.0 12 Q9Y2T2,P61966,Q96CW1,P63010,O43747,Q92572,P53680,O95782,O00203,Q9P253,O14617 11 +Distal axon 0.2728353682172661 0.0939773334626799 0.9251271623122206 1.0 1.0 61 P07196,P51116,P51114,P07900,O75312,Q13561,Q9UPT5,P50570,Q99720,Q96A49,P51790,Q02790,Q96A65,Q06787,P05067,Q92859,Q8N5V2,O75150 18 +Extrinsic component of endosome membrane 0.377715091678411 0.0867793332805541 0.9308469152947004 1.0 1.0 4 Q9Y5X3,P04083,A4D1P6 3 +U2af complex 0.4732359313942818 0.0802655532529281 0.9360260543123607 1.0 1.0 3 P26368 1 +Transcription preinitiation complex 0.3700987306064739 0.0729067941667302 0.941880287371305 1.0 1.0 4 P19447,P29083,P13984 3 +Dynein axonemal particle 0.3296641264465092 0.0697470349438049 0.94439500443706 1.0 1.0 6 Q86Y56,P31948,Q9Y265,P08238,Q9Y230 5 +Myosin filament 0.46446700507615 0.0683999125762831 0.9454672914229094 1.0 1.0 3 P35579,P35580 2 +Spectrin associated cytoskeleton 0.366996967264683 0.0675292452358735 0.946160380825873 1.0 1.0 4 O15020 1 +Lamin filament 0.4616528825144277 0.0647903089069661 0.9483409576106968 1.0 1.0 3 P20700 1 +Ciliary tip 0.2830028785598946 0.0600758145298379 0.9520952523726378 1.0 1.0 11 Q9Y366,Q2M1P5,Q7Z4L5,A0AVF1,Q15555,Q6PHR2 6 +Apical junction complex 0.2452204507502466 0.0587173783819734 0.9531772172723882 1.0 1.0 32 Q9NR77,Q86UE4 2 +Trans golgi network transport vesicle 0.2592361770067447 0.0542403724619452 0.956743655437048 1.0 1.0 16 P11717,O43493,P49755 3 +Clathrin adaptor complex 0.285310734463284 0.0472238639544608 0.9623348080515156 1.0 1.0 9 Q9Y2T2,P61966,Q96CW1,P63010,O43747,P53680,O95782,O00203 8 +Endolysosome membrane 0.2853107344632822 0.0472238639544557 0.9623348080515196 1.0 1.0 9 Q00610,P09496,Q96CW1,P63010,P53680,Q9NP58,P01130,O95782 8 +Cyclin cdk positive transcription elongation factor complex 0.433605864110524 0.0391236671222519 0.9687917917771028 1.0 1.0 2 Q9NYV4 1 +Filopodium 0.2418366854709419 0.0358133473205124 0.9714311902722448 1.0 1.0 29 P51116,P06756,P51114,P15291,Q06787,P05067 6 +Signal recognition particle 0.3127440263971085 0.0322750651046468 0.974252694006558 1.0 1.0 6 Q9UHB9 1 +Synaptonemal structure 0.2799103517692449 0.0322240017798338 0.9742934154637206 1.0 1.0 9 Q92791,P53350 2 +Anchored component of membrane 0.2808703023453056 0.0308277707499805 0.9754068930854378 1.0 1.0 10 Q15286,P36551,Q9NQX3,P20337,P51149,Q9ULX3,Q9BZM4,P20339,P61020 9 +Nucleoid 0.2389206076305214 0.0252208219036767 0.9798788287603994 1.0 1.0 36 P45880,Q04837,Q96RR1,Q9NVI7,P21796,Q12849,P06576,P05141 8 +Trapp complex 0.4204737732656566 0.0223994920817081 0.9821292855111844 1.0 1.0 3 Q7Z392,Q8IUR0 2 +Mpp7 dlg1 lin7 complex 0.3896250352410499 0.0141870567574557 0.988680746160502 1.0 1.0 2 Q5T2T1 1 +Neuron projection terminus 0.2477349943374763 0.0129637134022287 0.98965674293745 1.0 1.0 17 Q05682,Q14141,P61421,Q9UQB8,P11142,Q7L576,P05771,O75494,P27708,P51790,P20339,Q06787,P43378,Q15334,O75150,O14617 16 +Ripoptosome 0.384550324217655 0.0122988500128121 0.99018718484364 1.0 1.0 2 Q13546 1 +Dna replication preinitiation complex 0.2729584628426118 0.0101319957242519 0.9919159753558096 1.0 1.0 10 P25205,O75419,P33993,P49736,Q9UBD5,Q9BRX5,Q14566,P33991,Q9BRT9 9 +Clathrin complex 0.3402875669579922 0.0018423468679954 0.9985300207099606 1.0 1.0 2 P09496 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2372f3bd5832689c25f5afd00d7bf7f545fab7be --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atg1 ulk1 kinase complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Glycosylphosphatidylinositol n acetylglucosaminyltransferase gpi gnt complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner acrosomal membrane", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiia complex", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC10", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG2B", "ATG3", "ATG7", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLM", "BLOC1S1", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C18orf32", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CASP3", "CASP8", "CAST", "CBFB", "CBL", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC58", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CENPH", "CENPI", "CENPK", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG1", "COG3", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPAGT1", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM126A", "FAM129B", "FAM162A", "FAM208A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FOXRED2", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK2", "HOOK3", "HP1BP3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "IVD", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14A", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "METTL3", "METTL9", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MGAT1", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEO1", "NES", "NFRKB", "NFS1", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTULIN", "OXA1L", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF5A", "PHF6", "PHF8", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STT3A", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "SYVN1", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAMM41", "TAP1", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLK2", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIP11", "TRIP12", "TRIP13", "TRMT10C", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGT8", "UHRF1", "ULBP3", "ULK3", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WTAP", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZFC3H1", "ZFPL1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF106", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYG11B", "ZYX", "ZZZ3"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ABHD12", "ACADVL", "ACOX1", "ACP6", "ACSL6", "ACTN4", "ADPGK", "AFG3L2", "AGK", "AGPAT5", "AIP", "ALDH3A2", "ALG1", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANKLE2", "ANKRD13A", "ANXA1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APLP2", "APOL2", "APOO", "APOOL", "APP", "ARFIP2", "ARHGEF7", "ARL1", "ARMC10", "ARV1", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1E1", "ATP7A", "ATPIF1", "ATXN10", "B4GALT1", "B4GAT1", "BAIAP2", "BCAP31", "BCCIP", "BCKDHB", "BCKDK", "BCS1L", "BICD2", "BLOC1S1", "BNIP1", "BRI3BP", "BSG", "BUB1B", "C12orf43", "C12orf73", "C14orf2", "C18orf32", "C19orf70", "C1QBP", "CACYBP", "CAD", "CALD1", "CALU", "CANX", "CASK", "CBX5", "CCDC134", "CCDC47", "CCT2", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC45", "CDIPT", "CDK12", "CDKAL1", "CDS2", "CERS1", "CERS2", "CERS5", "CETN2", "CHCHD3", "CHMP1A", "CHMP2B", "CHMP3", "CHMP7", "CHST14", "CISD1", "CKAP4", "CLCC1", "CLCN3", "CLCN6", "CLN5", "CLPP", "CLPTM1", "CLTA", "CLTC", "CNNM4", "CNPY2", "COA3", "COG1", "COG3", "COG5", "COLEC12", "COLGALT1", "COPS3", "COPS4", "COPS5", "COPS8", "COQ5", "COQ8A", "COQ8B", "COQ9", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRTAP", "CSNK1A1", "CTNNB1", "CTNND1", "CTSA", "CTSC", "CUL7", "CYB5B", "CYFIP1", "CYP51A1", "DAGLB", "DBN1", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHFR", "DHRS1", "DHRS13", "DIABLO", "DNAAF5", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DOLPP1", "DST", "DYM", "EBP", "ECE1", "EHD1", "EHD4", "EI24", "EIF4A3", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "ENPP1", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESYT2", "ETFDH", "EXOC2", "EXOC4", "EXOC7", "EZR", "FADS1", "FAF2", "FAM162A", "FAM49B", "FAM8A1", "FAR2", "FASN", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP9", "FKRP", "FLII", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "GAA", "GALNT1", "GALNT4", "GBA", "GCC1", "GDAP1", "GDE1", "GGCX", "GGH", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLG1", "GM2A", "GNS", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPHN", "GPR107", "GPR108", "GPX8", "GRSF1", "GTF2E1", "GTF2F2", "GTF2H1", "GUSB", "HACD3", "HADH", "HAUS1", "HAUS5", "HCCS", "HEXA", "HEXB", "HGS", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMGCR", "HMOX1", "HMOX2", "HNRNPD", "HNRNPM", "HNRNPR", "HOOK2", "HPS6", "HS2ST1", "HSD17B11", "HSD17B12", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA8", "HTT", "ICMT", "IFT52", "IGF2R", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INA", "IPO7", "IPO8", "IQCB1", "IQGAP3", "ISOC1", "ITGAV", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KIAA0319L", "KIAA0368", "KIAA1468", "KIF5B", "KIF7", "KPNA2", "KTN1", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LARS", "LBR", "LDAH", "LDLR", "LETM1", "LGALS3BP", "LGMN", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LRRC59", "LSM5", "LYSMD3", "MAD1L1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MAPRE1", "MAPRE2", "MBOAT7", "MCL1", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "MCU", "MCUB", "MFF", "MFGE8", "MFN1", "MFN2", "MGAT1", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIGA1", "MINDY3", "MIPEP", "MMGT1", "MMS19", "MOB4", "MPC2", "MPP2", "MPP5", "MPP7", "MPV17L2", "MRPL10", "MRPL28", "MRPL45", "MRPL46", "MRPL48", "MSMO1", "MSN", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "MYH10", "MYH9", "MYL6", "MYO5A", "NAGLU", "NAP1L1", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEO1", "NGEF", "NLN", "NLRX1", "NNT", "NOB1", "NPC1", "NPC2", "NRM", "NUCB1", "NUCB2", "NUDT12", "NUDT9", "NUP210", "NUP35", "NUP37", "NUP54", "NUP93", "NUPL2", "OCIAD1", "OCLN", "OMA1", "OPA1", "OPA3", "ORC3", "OS9", "OSTM1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PACSIN2", "PANX1", "PARL", "PCM1", "PCYOX1", "PCYOX1L", "PDCL3", "PDK1", "PDP1", "PECR", "PEX14", "PEX19", "PEX3", "PFDN2", "PFDN6", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PIGG", "PIGK", "PIGU", "PIK3C2A", "PIP4K2C", "PISD", "PKMYT1", "PLA2G15", "PLBD2", "PLCB3", "PLD3", "PLD6", "PLK1", "PLXNB2", "PMPCA", "PNPLA8", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "PON2", "POR", "PPHLN1", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PRCP", "PRELID1", "PRIM1", "PRIM2", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKRA", "PRPF39", "PRPF40A", "PRRC1", "PSAP", "PSMB2", "PSMB4", "PSMB6", "PSMD11", "PSPC1", "PTGES2", "PTPN9", "PTPRF", "PXMP2", "QPCTL", "QSOX2", "RAB10", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RABAC1", "RABEPK", "RACGAP1", "RAD21", "RALA", "RANGRF", "RBM39", "RCN1", "RCN2", "RDH13", "RDX", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RFT1", "RHBDD2", "RINT1", "RIPK1", "RMDN1", "RMND1", "RNASET2", "RNF40", "RPN1", "RPN2", "RRM2B", "RTN3", "RTN4", "RUVBL1", "RUVBL2", "S100A13", "SACM1L", "SAMM50", "SAR1A", "SC5D", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCO1", "SCO2", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC62", "SEL1L", "SEPT2", "SEPT6", "SET", "SF3A1", "SFPQ", "SFXN1", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIL1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SMC3", "SNAP29", "SNAPIN", "SNRNP70", "SNRPC", "SNTB2", "SNX27", "SNX5", "SNX6", "SPAG9", "SPART", "SPCS2", "SPHK2", "SPNS1", "SPPL2A", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRP68", "SRP9", "SRPRB", "SRSF10", "SSBP1", "SSR1", "SSR4", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STIM1", "STIP1", "STK26", "STOM", "STOML2", "STRN", "STT3A", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "SUN1", "SUN2", "SURF4", "SV2A", "SYAP1", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "SYVN1", "TADA3", "TAF6", "TAF6L", "TAF7", "TAMM41", "TAP1", "TBL2", "TDRKH", "TECR", "TEX264", "TFRC", "TGOLN2", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TM9SF2", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMEM11", "TMEM126A", "TMEM14C", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOR1AIP1", "TPD52", "TPM1", "TPM4", "TPP1", "TPR", "TRAM1", "TRAPPC11", "TRAPPC5", "TRIP11", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TTC19", "TTC21B", "TTC26", "TTYH3", "TUBGCP4", "TWNK", "TXNDC12", "TXNDC15", "TXNDC16", "TYSND1", "U2AF2", "UBE2G2", "UBE2K", "UBE2S", "UBQLN4", "UGCG", "UGGT1", "UGT8", "ULBP3", "ULK3", "UNC119B", "UQCR10", "UQCRQ", "USMG5", "UTRN", "VANGL1", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VPS13A", "VPS18", "VPS25", "VPS33B", "VPS51", "VPS52", "WASHC3", "WASHC5", "WDR91", "WFS1", "WLS", "XPO4", "XRCC6", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YME1L1", "YWHAE", "ZADH2", "ZFPL1", "ZMPSTE24", "ZNF622", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_gomf/advanced/idx2term.json b/msigdb_gomf/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7a21443d912b7af4921fd0df5ac5c49028ead27c --- /dev/null +++ b/msigdb_gomf/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Proton transmembrane transporter activity", "2": "Organic anion transmembrane transporter activity", "3": "Ion transmembrane transporter activity", "4": "Active ion transmembrane transporter activity", "5": "Cation transmembrane transporter activity", "6": "Metal ion transmembrane transporter activity", "7": "Steroid binding", "8": "Molecular transducer activity", "9": "Secondary active transmembrane transporter activity"} \ No newline at end of file diff --git a/msigdb_gomf/advanced/plot_0.png b/msigdb_gomf/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ab3ed438c0d0314538972089088b6e3f3d1d6456 --- /dev/null +++ b/msigdb_gomf/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12152948e29634d9637846db8eede898ef3fb7b302f360cbd7c3c32ac8edfd1d +size 218067 diff --git a/msigdb_gomf/advanced/plot_1.png b/msigdb_gomf/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e54d525c17a5df862cf86be8aaf7a035a22ddcef --- /dev/null +++ b/msigdb_gomf/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b03556ad9e41cef7b2d037a1a78f4d22471fc23f04fbbd89453900ac90d992f8 +size 205041 diff --git a/msigdb_gomf/advanced/plot_2.png b/msigdb_gomf/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..f405d59614fcffb0b1d01a0e0bb79fe3898463b3 --- /dev/null +++ b/msigdb_gomf/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88999169c53ff9b485a63a0d9ba5f9641f9e3a50ee06c56d913ad6738df557af +size 204351 diff --git a/msigdb_gomf/advanced/plot_3.png b/msigdb_gomf/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..9161df222b14175e30a5517fe603bca637d88346 --- /dev/null +++ b/msigdb_gomf/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9748792d427ac16f37bb2f4c6e27b21466c1bedaf6454bf35f7fb391174a6b51 +size 214299 diff --git a/msigdb_gomf/advanced/plot_4.png b/msigdb_gomf/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..5e520a8006c645f2e0997888eebd625cda8a7bc2 --- /dev/null +++ b/msigdb_gomf/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a22c648b4951a9802a4962f5ffe0f6d026a821bcab2fc8af3ac43db0e9ecb71b +size 210585 diff --git a/msigdb_gomf/advanced/plot_5.png b/msigdb_gomf/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..2ce606c7855974094709dda1e646c949fc5ac892 --- /dev/null +++ b/msigdb_gomf/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d3e9b21a897315151258043c67927ff19855d2de960c6bd1b536713f1371bf3c +size 210718 diff --git a/msigdb_gomf/advanced/plot_6.png b/msigdb_gomf/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..0986fb856b1ed911d9d2634718dff4ec15392d48 --- /dev/null +++ b/msigdb_gomf/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8d7f5d1da73cabae701823a45d16affc16ee33a63f36ba9422390c80a45c62e3 +size 205515 diff --git a/msigdb_gomf/advanced/plot_7.png b/msigdb_gomf/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..a19ad22546197fa120135e80674faf8cefb3ed9e --- /dev/null +++ b/msigdb_gomf/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5bc35621bce060eb568b2cf92d8dc7fc73a114ebafb7be78f231b75a234c92df +size 203302 diff --git a/msigdb_gomf/advanced/plot_8.png b/msigdb_gomf/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..b38c32b4f61274902d9acf25faafe9bfc6f7deda --- /dev/null +++ b/msigdb_gomf/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:443ce34c1da572a3655641d06025f4843d8e2665819d42eec8f370ce48e714a1 +size 206992 diff --git a/msigdb_gomf/advanced/plot_9.png b/msigdb_gomf/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..660189404046f9a22f299c2ffa9d0eb1e2417356 --- /dev/null +++ b/msigdb_gomf/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f70f79ccd62e9019be4e44e5a8d17b8569cea180fe4b6f04ee8634bfe11f51ec +size 201647 diff --git a/msigdb_gomf/basic/idx2term.json b/msigdb_gomf/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..193cde330f9bcc0741ac19df22a33a091620d3a3 --- /dev/null +++ b/msigdb_gomf/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Proton transmembrane transporter activity", "2": "Organic anion transmembrane transporter activity", "3": "Ion transmembrane transporter activity", "4": "Active ion transmembrane transporter activity", "5": "Cation transmembrane transporter activity", "6": "Metal ion transmembrane transporter activity", "7": "Steroid binding", "8": "Molecular transducer activity", "9": "Secondary active transmembrane transporter activity", "10": "Atpase coupled transmembrane transporter activity", "11": "Protein transporter activity", "12": "Inorganic molecular entity transmembrane transporter activity", "13": "Nucleobase containing compound transmembrane transporter activity", "14": "Lipid transporter activity", "15": "Organic acid transmembrane transporter activity", "16": "Tetrapyrrole binding", "17": "Nucleotide transmembrane transporter activity", "18": "Organophosphate ester transmembrane transporter activity", "19": "Active transmembrane transporter activity", "20": "Anion transmembrane transporter activity", "21": "Macromolecule transmembrane transporter activity", "22": "Snap receptor activity", "23": "Protein transmembrane transporter activity", "24": "Carbohydrate derivative transmembrane transporter activity", "25": "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "26": "Sterol binding", "27": "Primary active transmembrane transporter activity", "28": "Passive transmembrane transporter activity", "29": "Cholesterol binding", "30": "Hexosyltransferase activity", "31": "Abc type transporter activity", "32": "Atpase binding", "33": "Monooxygenase activity", "34": "Signal sequence binding", "35": "Purine nucleotide transmembrane transporter activity", "36": "Hydrolase activity hydrolyzing o glycosyl compounds", "37": "Alcohol binding", "38": "Cargo receptor activity", "39": "Sulfur compound transmembrane transporter activity", "40": "Transition metal ion transmembrane transporter activity", "41": "Vitamin transmembrane transporter activity", "42": "Fk506 binding", "43": "Macrolide binding", "44": "Serine hydrolase activity", "45": "Hydrolase activity acting on glycosyl bonds", "46": "Antiporter activity", "47": "Symporter activity", "48": "Calcium ion transmembrane transporter activity", "49": "Oxidoreduction driven active transmembrane transporter activity"} \ No newline at end of file diff --git a/msigdb_gomf/basic/plot_0.png b/msigdb_gomf/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f7eab764443c257ac14f69af9f246521c5a555d1 --- /dev/null +++ b/msigdb_gomf/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71072edb6eace3a7a027db132ed1109ec854a4165a7db2cc405fe6d4f9983ea4 +size 141145 diff --git a/msigdb_gomf/basic/plot_1.png b/msigdb_gomf/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..500161cb1e8d35e284217edf976065e905d335d9 --- /dev/null +++ b/msigdb_gomf/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de16576cf3a1745cf63dbf0642e2a2aa5a3c5649906246c0b4990edf7a90b1a8 +size 147154 diff --git a/msigdb_gomf/basic/plot_10.png b/msigdb_gomf/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..c0c0af82dd699ccf2bb19ff1e02151e18fbe2d0a --- /dev/null +++ b/msigdb_gomf/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:440a06a50d753c88311e702581418444febc61223b7db9c5d523ebde9bad76f9 +size 150212 diff --git a/msigdb_gomf/basic/plot_11.png b/msigdb_gomf/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..07edb300d1e318a932724ac36ab907e140e7cf7d --- /dev/null +++ b/msigdb_gomf/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ff37bb5ef4bb057b721e73ae5a2b2e7e2c7db437fd2b2b8fbb7ef02e06cb458 +size 144081 diff --git a/msigdb_gomf/basic/plot_12.png b/msigdb_gomf/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..abaca503367716c7715c018e63264c448f36fc40 --- /dev/null +++ b/msigdb_gomf/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3498a5ab59e29f26f910d3c83a37c844af8ea5684093979b0c290cb84ae248e3 +size 150797 diff --git a/msigdb_gomf/basic/plot_13.png b/msigdb_gomf/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..9c48fd4a528d20dcd14bc9809095bd35fe8d5987 --- /dev/null +++ b/msigdb_gomf/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6d78da27d50ff1475f9c74270e28c49d2c98bff71289d9157412563ff17b352 +size 152630 diff --git a/msigdb_gomf/basic/plot_14.png b/msigdb_gomf/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..0f4ec1bf34df783df6d0ebfcddf08d92d0a79d3a --- /dev/null +++ b/msigdb_gomf/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6a6866f7b71f3726b53af249f5d934480e938fc3e5a0f059e7520be9b030947 +size 137762 diff --git a/msigdb_gomf/basic/plot_15.png b/msigdb_gomf/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..21db983cc3b7099cead8b7701cd59cbe67192988 --- /dev/null +++ b/msigdb_gomf/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38606e178a345edbb0b900ebe2ae332d6f594b805e351e5b8221ab2d316b667e +size 149326 diff --git a/msigdb_gomf/basic/plot_16.png b/msigdb_gomf/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..594a436a69e4e024f440a6b23c8849ef4e27de5d --- /dev/null +++ b/msigdb_gomf/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a42b07f4622dea2ffd08d46dd1e28a6339efbe40b5f5295a55efc0756592c479 +size 138662 diff --git a/msigdb_gomf/basic/plot_17.png b/msigdb_gomf/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..c594b8a04c476ee1b19886ab5d49f5cc1608399f --- /dev/null +++ b/msigdb_gomf/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b684b7f8b9624ac64fd1b9c61a60e3eaa99a62169e263147dd354d0241bd5752 +size 149603 diff --git a/msigdb_gomf/basic/plot_18.png b/msigdb_gomf/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..802e5f860cf4054c25ca60141242bf11b7318b71 --- /dev/null +++ b/msigdb_gomf/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c9b620115ae24f1db849fc9c074b161282dd315c3e9abfffefcade6face57ed4 +size 149377 diff --git a/msigdb_gomf/basic/plot_19.png b/msigdb_gomf/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..849a82cfd8a8625a257a6d298ab6a3d32ac07ec5 --- /dev/null +++ b/msigdb_gomf/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c5c61d2b8285d33d3c65b4a76462d6505b899a85f075930180bafdebf1236ae +size 149457 diff --git a/msigdb_gomf/basic/plot_2.png b/msigdb_gomf/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..aee39191c33866073a3f3d61837fd6209ea63665 --- /dev/null +++ b/msigdb_gomf/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ad6a3f57e4b290c6d74f145c2991e51ade99d745fb6c61ecd1c00b5a333cce0c +size 148288 diff --git a/msigdb_gomf/basic/plot_20.png b/msigdb_gomf/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..edb0a80521e020c3fe0602d5d92d2c93fa212ae6 --- /dev/null +++ b/msigdb_gomf/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:affb74f36a5418e781b8dd63ea3d74ccac11bea1e26a0fd54c9b161bc8451564 +size 148277 diff --git a/msigdb_gomf/basic/plot_21.png b/msigdb_gomf/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..ff825d012f909513aec5481e92691fbaf7507cff --- /dev/null +++ b/msigdb_gomf/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:658979f3cace6cb7ed9036e0775fe5d4c461b1020d0467c8751bc3a8d37d4090 +size 147193 diff --git a/msigdb_gomf/basic/plot_22.png b/msigdb_gomf/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..b256e0df313cc0fae02e49f6bcd460f6ab34f01b --- /dev/null +++ b/msigdb_gomf/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71c1c1ee0009d3f1d8491ab6d5e599bc0bde280211f2ea8a26eb6e8ae8d9d6e4 +size 142963 diff --git a/msigdb_gomf/basic/plot_23.png b/msigdb_gomf/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..063587467e2406ad431864dca5d5403903f2c279 --- /dev/null +++ b/msigdb_gomf/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5564a4b2a602366609ab0454171d6e15531e7cde61a51b7e751ab016b5b54efd +size 146366 diff --git a/msigdb_gomf/basic/plot_24.png b/msigdb_gomf/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..0c4f1cc7fbd381ffb716f52022c45caba377d48c --- /dev/null +++ b/msigdb_gomf/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ebd603cbed0d969585120612cd14057b49ab5dc5aa8e4174616dcf764d02322 +size 147654 diff --git a/msigdb_gomf/basic/plot_25.png b/msigdb_gomf/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..548ec4ed1da3687a2875bd2e57e00fd738a9d948 --- /dev/null +++ b/msigdb_gomf/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4db2573fff51d9f95e20f85e7dee2cb7fb87f7c4fe2944a607c36c28f7f2f59a +size 147892 diff --git a/msigdb_gomf/basic/plot_26.png b/msigdb_gomf/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..2b144563b9989ea4daf40fc1288b37d09caebc91 --- /dev/null +++ b/msigdb_gomf/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d5858d259a29d9beba0ee1a1d2d7faf37ec11db0341ed33f8dcf6275d720ac6 +size 138210 diff --git a/msigdb_gomf/basic/plot_27.png b/msigdb_gomf/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..cc8a269c3a1605fc82a801f574c55981462b37d4 --- /dev/null +++ b/msigdb_gomf/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7b3547bbc523715f0fe0d0495766e8778262026b536033a6800808eae26bff2b +size 146624 diff --git a/msigdb_gomf/basic/plot_28.png b/msigdb_gomf/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..d12177986f9d970d32a5878f70cf43067e4067de --- /dev/null +++ b/msigdb_gomf/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e526ebc4567f30b9259129046d56c5312538d7bdd874483c32f222765214af5b +size 145357 diff --git a/msigdb_gomf/basic/plot_29.png b/msigdb_gomf/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..f7fc359b6b9fd8e972f82e2e0477310269cd3063 --- /dev/null +++ b/msigdb_gomf/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f6792537eb3f827090789c6ea1d8a4c42246c0fe49376e7ba3096bf5ce725e5 +size 139105 diff --git a/msigdb_gomf/basic/plot_3.png b/msigdb_gomf/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..c0b32a49ce19e091f69926fba48143b1feabc689 --- /dev/null +++ b/msigdb_gomf/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e229e91fc527403a2e7ba12a2de1242967a2db154954564819a5322915014bcc +size 148844 diff --git a/msigdb_gomf/basic/plot_30.png b/msigdb_gomf/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..a6a798effc50ebd40c6dc4c83fb41668649a8ca2 --- /dev/null +++ b/msigdb_gomf/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:226d4b727145fa0864a535616a3148d52673242b56dafecf4004c9c63b18eb13 +size 146368 diff --git a/msigdb_gomf/basic/plot_31.png b/msigdb_gomf/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..09b47403932e8488f85be796c6f6091b15d2a0ae --- /dev/null +++ b/msigdb_gomf/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b67f43034e13ce94c81570adf38dc646ab076ff4f4e25994a82dcfac2264385d +size 142876 diff --git a/msigdb_gomf/basic/plot_32.png b/msigdb_gomf/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..6c2960977c1b3b407eb3c887b901238d4cac99d6 --- /dev/null +++ b/msigdb_gomf/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e3524d1cf9286638158354353f31d06e38eac85f220a2171486bb24f5580a5f +size 142723 diff --git a/msigdb_gomf/basic/plot_33.png b/msigdb_gomf/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..002726552d186749a38e7687dd0b39e6dec4bcb6 --- /dev/null +++ b/msigdb_gomf/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a21ace57e6655a22b9a41db033590982bb410e33858ed9c2a43819e57d4612fa +size 144780 diff --git a/msigdb_gomf/basic/plot_34.png b/msigdb_gomf/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..a243b7729d24f2e6f12858f1461026eae42292db --- /dev/null +++ b/msigdb_gomf/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d2bc6411e83d352747a551eece1bb81fc18d4b64c305fef30c3c17313ad005e +size 142524 diff --git a/msigdb_gomf/basic/plot_35.png b/msigdb_gomf/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..85edb9fac62cd965b07dfe8e9a1acd9367e07dde --- /dev/null +++ b/msigdb_gomf/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ec2f4b43bbe2ae074d68f5a2998675a4992a81ec23fb75a164adffc3200cdf4c +size 149459 diff --git a/msigdb_gomf/basic/plot_36.png b/msigdb_gomf/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..8d7a91bd59168547f3349dd483c51e54151ecbe4 --- /dev/null +++ b/msigdb_gomf/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c5ef01d7fbdd8e2e440682da0f6ac3b6c849bfd06f2bf5bdad53ad1272e932b +size 152099 diff --git a/msigdb_gomf/basic/plot_37.png b/msigdb_gomf/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..40657fb87992c37902ef0a78290ed47919b3f146 --- /dev/null +++ b/msigdb_gomf/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:730856f19d7dd6a8bb0e87503de22eaca35a0deec65a04261c429ac40ce9526b +size 137492 diff --git a/msigdb_gomf/basic/plot_38.png b/msigdb_gomf/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..46dec28e1608c2b80e9353bd46870599d49afc80 --- /dev/null +++ b/msigdb_gomf/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2961f9c6a77f3dc619d61a8377f7b8a932dc976de69b84b82fcc5328150e1b53 +size 143658 diff --git a/msigdb_gomf/basic/plot_39.png b/msigdb_gomf/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..d828aeba01e3168aea83b3283d65e99f20b42fab --- /dev/null +++ b/msigdb_gomf/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89ec67c2768a817b56521047348d66ce02d77939d3d4398ced3be140eeb56db3 +size 147124 diff --git a/msigdb_gomf/basic/plot_4.png b/msigdb_gomf/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..164eb4a79d0b4722f0c9904ec014d0c73c4d2b31 --- /dev/null +++ b/msigdb_gomf/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc22cf4105edae791be1924a83e70c6e0dd09f84cf49759e33e5e47f84330970 +size 150142 diff --git a/msigdb_gomf/basic/plot_40.png b/msigdb_gomf/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..0bd51825a051171044990e61c14e40ef931efefc --- /dev/null +++ b/msigdb_gomf/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5226984b9404a83781fb428303eacf23a80e8d358931977bccd13dfdec6afdd +size 145583 diff --git a/msigdb_gomf/basic/plot_41.png b/msigdb_gomf/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..4374e7429ff5d6190693d1c4a1b7a86109f2c96a --- /dev/null +++ b/msigdb_gomf/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ee754a1bfc4eb8e95d3f9150c553bb393896550cd23580caefab455b66a8e680 +size 145192 diff --git a/msigdb_gomf/basic/plot_42.png b/msigdb_gomf/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..24bf779dd2e19a9230cdf6178970538208a9db09 --- /dev/null +++ b/msigdb_gomf/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84cdbdf7f67c831a3b2f38c48d7167d371e95df31cc2067a54844d1bb2fed47c +size 137904 diff --git a/msigdb_gomf/basic/plot_43.png b/msigdb_gomf/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..9be46b282bbf8d7cbd4f69cb33f85771d26250dc --- /dev/null +++ b/msigdb_gomf/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:544f469707dafd7c80237fe3061c32255469e562bf5b1e9b16022a54dc4527a8 +size 139536 diff --git a/msigdb_gomf/basic/plot_44.png b/msigdb_gomf/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..89210ef56ef6f5a728b38d962c316d4673801f07 --- /dev/null +++ b/msigdb_gomf/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ec35270a52d2315c1dda3dcbb3d346f58aaf9026589114404ea3e656de3e9ef +size 143097 diff --git a/msigdb_gomf/basic/plot_45.png b/msigdb_gomf/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..46b574739573dffd91c7467e799a29729f7cd29e --- /dev/null +++ b/msigdb_gomf/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78fba4d22c34272b75f18af61bea9e1b3efa6bc91aa6c7cc4168f39bbd7d7e27 +size 153511 diff --git a/msigdb_gomf/basic/plot_46.png b/msigdb_gomf/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..3c935eb0c7b536924ea78a3c0bbb74097370fbf7 --- /dev/null +++ b/msigdb_gomf/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9e79cc8e5474454803e58a1c2ddf70f9d97ab7de63ec95a06f5a624421906cb +size 137397 diff --git a/msigdb_gomf/basic/plot_47.png b/msigdb_gomf/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..cbd6c198ac6b5a2ba4f66f3ef943ea21e536cb24 --- /dev/null +++ b/msigdb_gomf/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b6a4a55ee21ea0f29b0e0c7636fc5646805175bdd50c405d5a537afff550cbc +size 136261 diff --git a/msigdb_gomf/basic/plot_48.png b/msigdb_gomf/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..c6016bc722c4258d6a22e8c4972b2a0f859834a2 --- /dev/null +++ b/msigdb_gomf/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:467bd029c9c8ddc56e42d6f40c70abce279237ea36682f0203014d3064ab8824 +size 144169 diff --git a/msigdb_gomf/basic/plot_49.png b/msigdb_gomf/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..7580732c349ce4171fdc968b99c987b26d0f7baa --- /dev/null +++ b/msigdb_gomf/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1541ca5d1bd02e20ca443586807b9a342d2053ecc3538566df71e8ace692e98f +size 143846 diff --git a/msigdb_gomf/basic/plot_5.png b/msigdb_gomf/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..464e2bc900e1d39544a3a9dc387e8a490823ac4b --- /dev/null +++ b/msigdb_gomf/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8f5deae70eeb7b2e599da6f493cc3e8a432459a31ea5f48a985b1efc09f19bd +size 150127 diff --git a/msigdb_gomf/basic/plot_6.png b/msigdb_gomf/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..0fbf67b7741b3b2841ac9312948cc7edea75cadc --- /dev/null +++ b/msigdb_gomf/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17799f53b631b0313c0b4045291ac99f1c7434477289afa6880059419d65e0ec +size 149298 diff --git a/msigdb_gomf/basic/plot_7.png b/msigdb_gomf/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..6dbbfb85c9d24f61f73e088aa6dad22c43a2369b --- /dev/null +++ b/msigdb_gomf/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ca3d4cff5ba7c747188bfdc349821d6ce016852281eb4b979b8f4c2178d75e2 +size 138917 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..060d1daa18c24530cb0aaad00615fb1cb403deaf --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27598c0a08d27be1bb7ce47f9e887f759da755164f31b79dc83611318fb7de75 +size 145492 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..14cbf410a2f5ba0263e4492a96aa5f275e2817a5 --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be9bfcdf342908b2f808701f0f7a55b79e661e2a5e538da03a444181996a376f +size 148662 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..cc756f1c8a639b85838c7e47dba236d48232c76c --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:172a5878e2423ee8df89a4cc4b211ba02c5be0e15c9d04c114b3ee788fe2e2fe +size 208253 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..700dd80dfbd91b1b030b0d0e308e7f4119d07684 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,90 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter activity 113 202 7.615942664882279 2.6177387589570563e-14 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 2.389775209079317e-23 3.4547551545681746e-06 1.5056091902533215e-08 8.647037891744883e-15 1.4572162824821192e-23 +Proton transmembrane transporter activity 19 40 4.104588222984516 4.0503568182526095e-05 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 7.89296169362441e-09 0.0050226976439289 7.389910731518841e-05 1.466381635734091e-06 1.423773902401653e-09 +Organic anion transmembrane transporter activity 21 33 4.041109517596076 5.319890520349979e-05 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 1.0639185632756192e-05 0.3315322885250054 0.1967082241040804 0.0010205325993841 1.2606619012664512e-05 +Ion transmembrane transporter activity 67 117 4.019661283690597 5.828187229295345e-05 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 1.9700739759946137e-14 0.0031507382562496 0.0001824164248195 1.6404833043726783e-09 8.271245182162475e-15 +Active ion transmembrane transporter activity 35 51 3.95182245555798 7.755827510536051e-05 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 1.6123163409974106e-07 0.4288200159845614 0.1046331311972006 0.0005710631251204 4.397959849631766e-08 +Cation transmembrane transporter activity 39 81 3.931667594298448 8.435865554101696e-05 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 2.86542779915293e-10 0.0229384919777869 0.0067573778891409 3.2067790707302085e-06 1.0717632077681844e-10 +Metal ion transmembrane transporter activity 20 31 3.917127551469828 8.961034086918396e-05 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.0020734984745805 0.4396258949303272 0.6943670866160305 0.0758363007333116 0.0023639052461662 +Steroid binding 10 23 3.8179655187506114 0.0001345567261592 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 1.5309434521120686e-05 1.0 0.0803922289273931 0.000162079776431 1.7491284227584308e-05 +Molecular transducer activity 21 38 3.760473950646869 0.0001695917352382 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.5860712636128327 1.0 0.9198528304142816 0.4347491239309696 0.6060751745438748 +Secondary active transmembrane transporter activity 19 26 3.7589659143115295 0.0001706170775812 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.0031159361504447 1.0 0.2072288126229632 0.0621642703962852 0.0010815371106456 +Atpase coupled transmembrane transporter activity 22 32 3.665885243372118 0.0002464844455325 8.072815533980583 22.696601941747577 0.8561067713091313 0.3392846662603397 4.166386392056555 3.892074110340729 1.3163009809214623 0.3229730128136945 0.0003839504721476 1.0 1.0 0.1655021226103433 0.0004297622117065 +Protein transporter activity 9 17 3.616777572901632 0.0002982934174133 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 6.682539975232402e-09 5.086318889591563e-06 3.3768958612978955e-06 8.02228304527226e-08 7.754490474184296e-09 +Inorganic molecular entity transmembrane transporter activity 43 92 3.608664795993559 0.0003077769796893 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 4.779890546610277e-12 0.0054817326666829 0.0001094203271441 2.139236500254052e-08 1.764076165645557e-12 +Nucleobase containing compound transmembrane transporter activity 12 17 3.582438923038119 0.000340401219971 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 1.423668646793497e-07 0.1403531442218371 0.266209970857853 0.0001015515149626 1.644522092588519e-07 +Lipid transporter activity 13 28 3.5293352327008924 0.0004166050351641 6.546116504854369 19.805825242718445 0.7389006587243017 0.301332987440896 3.074370954053146 3.741159812966952 1.4134673193588587 0.2984913911167897 0.0035816812306788 0.3056056721424713 0.5259644699110895 0.1163456461629851 0.0039622831833118 +Organic acid transmembrane transporter activity 14 24 3.46428488886285 0.0005316431490867 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0156047854966435 0.2752604452820565 0.1388614812827933 0.0059425292278447 0.0168669379700177 +Tetrapyrrole binding 9 18 3.439865581607899 0.000582003165112 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0002091298381229 0.0001150461613963 0.0001612622666265 4.204252026569053e-05 0.0002346698535802 +Nucleotide transmembrane transporter activity 11 15 3.4151265037615004 0.000637523953193 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 1.2867458858644684e-08 0.0944323477659319 0.1837383274168749 7.604978655560818e-06 1.4746353247306191e-08 +Organophosphate ester transmembrane transporter activity 11 15 3.4151265037615004 0.000637523953193 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 2.2585121555431183e-08 0.0987043131013681 0.191600110602388 1.0246004736236846e-05 2.5866223242464448e-08 +Active transmembrane transporter activity 49 88 3.348065127794179 0.0008137788498279 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 2.8483969234508664e-08 0.2459530387672467 0.0130891925218009 0.0001149078722759 1.0496570227297994e-08 +Anion transmembrane transporter activity 33 52 3.3344148597265293 0.0008547906422846 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 1.162174009619723e-07 0.1184945425124205 0.033005107755267 5.2829178733530186e-05 3.2795365500612755e-08 +Macromolecule transmembrane transporter activity 6 13 3.2721584337024963 0.0010672974865328 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 1.9982918453667788e-06 1.9820323514244016e-06 1.0236679094826864e-06 5.543951850167897e-06 2.2237850571674797e-06 +Snap receptor activity 11 16 3.167786788913157 0.0015360412561356 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.000158928930674 1.0 0.2802926639431586 0.0088087297166582 0.0001753252601336 +Protein transmembrane transporter activity 6 12 3.142271258063852 0.0016764264536224 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 4.382901822134934e-07 9.8377873283803e-07 4.180168207037102e-07 1.8818469985730976e-06 4.886716881718799e-07 +Carbohydrate derivative transmembrane transporter activity 8 12 3.1299740572579218 0.0017482174157885 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 1.919735629626428e-05 1.0 1.0 0.0033024410276518 2.128341707780042e-05 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 14 34 3.1020271737713543 0.0019220031454172 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0047905750987067 0.0094477783308586 0.0122106671185157 0.0750173773780456 0.0053243369879504 +Sterol binding 6 18 3.06489447565646 0.0021774680980954 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0013880477544212 1.0 0.2941077913158182 0.0107757845080475 0.0015071148532441 +Primary active transmembrane transporter activity 35 64 3.04214307027612 0.0023490021696095 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 9.488367487637124e-07 0.109317488334835 0.028278569718715 0.0006520562274492 1.1846365187815352e-06 +Passive transmembrane transporter activity 15 39 3.0349906018197705 0.0024054318237216 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.0031223825509356 0.0163471034255926 0.0239832744272861 0.020682535454445 0.0012316476116813 +Cholesterol binding 6 15 3.0214087615302607 0.002516014527546 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0004343211420714 1.0 0.2518545844225215 0.0056128198685199 0.0004732841187851 +Hexosyltransferase activity 21 38 3.0008697876156107 0.0026920965802468 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.0964816534929714 1.0 0.6695171460893661 0.0584431730757671 0.1030303123093005 +Abc type transporter activity 10 13 2.996768132968178 0.0027285816239754 3.0194174757281553 7.652912621359223 0.9831250219385844 0.2361571806590424 1.9482657586917436 2.350049836723345 1.2743804993059251 0.258194993176919 0.0296850028190536 1.0 1.0 0.0217985290060267 0.031065887399213 +Atpase binding 11 29 2.98903562718579 0.0027985949707627 7.101941747572815 27.883495145631063 0.4324538219085727 0.5124445450748666 3.2760229435557595 2.201283698181438 0.9496598819558206 0.3233068270066163 0.0120630038630547 1.0 1.0 0.4697159455465771 0.0130614889048102 +Monooxygenase activity 5 8 2.988393572884794 0.0028044815448797 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0014751485015756 0.0002645755687248 0.0001188562693173 0.0004179970223822 0.0015869747860804 +Signal sequence binding 7 30 2.9535477720022816 0.0031414398212747 5.560679611650485 26.50242718446602 0.435828138514089 0.5798441286349703 3.257360227950366 2.1761045475756564 0.8353222176818301 0.3288364338889158 0.0005225221975125 0.0151070197534971 0.0065760397653667 0.0003658042695641 0.0005743066382168 +Purine nucleotide transmembrane transporter activity 8 12 2.9495133226569616 0.0031827485031685 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 4.384493228336404e-06 1.0 1.0 0.0004862334359502 4.818994730788961e-06 +Hydrolase activity hydrolyzing o glycosyl compounds 11 24 2.89247379595903 0.0038222106447158 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 1.240093013860134e-05 0.2031027035797352 0.0775813155228076 0.0001418153943193 1.4177363886845684e-05 +Alcohol binding 10 17 2.7985672271324744 0.005132988300093 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.009329062833678 1.0 0.3837329617110586 0.0324447271269302 0.0100459976774882 +Cargo receptor activity 9 11 2.779001980627622 0.0054526192635637 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 0.0097790119883011 1.0 1.0 0.1467432355955838 0.0103633783340074 +Sulfur compound transmembrane transporter activity 5 9 2.6795027734187618 0.0073731592459818 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0003471406336639 1.0 0.2445730022705269 5.657491778833551e-05 0.000378511976274 +Transition metal ion transmembrane transporter activity 5 8 2.662701102363105 0.0077516235091339 2.2597087378640777 4.444174757281553 1.267846808399692 0.205487024774009 1.5353529408674886 1.9618423203326616 1.2931295194130703 0.2516620757205828 0.0007580426681942 0.1071891284628969 0.2070995190727305 0.0002335266734922 0.0008169542553505 +Vitamin transmembrane transporter activity 5 7 2.66106675154045 0.0077893513104643 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.001650969453088 0.0858288536093336 0.1677870330809631 0.0102137155300364 0.0017585862412997 +Fk506 binding 5 7 2.629074121602924 0.0085617697182105 1.983009708737864 6.422330097087379 0.7710035079475605 0.4104541026784208 1.4588872837549367 0.7512361384385784 1.0178387667233504 0.3228401619923597 2.6683987719570872e-05 1.0 6.936272072908627e-05 0.0010588751859522 2.858966188275996e-05 +Macrolide binding 5 7 2.629074121602924 0.0085617697182105 1.983009708737864 6.422330097087379 0.7710035079475605 0.4104541026784208 1.4588872837549367 0.7512361384385784 1.0178387667233504 0.3228401619923597 5.1265180635653765e-05 1.0 9.839858993160587e-05 0.001485709034831 5.489393781591606e-05 +Serine hydrolase activity 13 21 2.6222512439495453 0.008735100954258 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0074643121616571 0.2031027035797352 0.0011293669878184 0.0284489140367958 0.0080473050001108 +Amide transmembrane transporter activity 4 7 2.6161505769372937 0.0088927331463173 1.9781553398058251 4.745145631067961 1.408683964326367 0.195466717632665 1.3391087077639925 1.811666809674734 1.0002201259794938 0.2223338014085611 0.0021155878345267 0.0901405579438761 0.1758008751515455 0.0011993766429203 0.002252196025852 +Hydrolase activity acting on glycosyl bonds 12 31 2.611167971393785 0.0090233561726671 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 0.000164259692121 0.2922756805728106 0.1554832015057707 0.0003656395100037 0.0001875770683042 +Antiporter activity 9 12 2.590144771981133 0.0095935576905357 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.0100042860913544 1.0 0.3143397790261298 0.2436114581565515 0.002448268499096 +Symporter activity 9 12 2.5300441290010136 0.0114048181606603 3.638349514563106 9.1747572815534 0.9770544165414302 0.3122690599192905 2.3735568316725377 2.065327188945721 1.1044541290009051 0.3081067804681572 0.0580802807538155 1.0 0.3467918934582977 0.0901467992310857 0.0610180463767549 +Calcium ion transmembrane transporter activity 6 16 2.5194593392399964 0.0117535214538611 4.682038834951456 13.276699029126211 0.2388683150344522 0.4966462427664995 2.540615268048159 1.6898155172183935 1.0404105676043174 0.3190267550516111 0.0239031738047001 0.1993158438338612 0.3655284832956332 0.6850187335780784 0.0254217837170298 +Oxidoreduction driven active transmembrane transporter activity 9 32 2.51734180475433 0.0118244055884886 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 0.0006663557070935 0.0343104139968933 0.0029226642017144 0.0007104622897235 0.0007440053524939 +Antigen binding 6 8 2.503190526948372 0.0123079266980523 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 0.0005922430121995 0.1029565435856987 0.1993869387044997 0.1060727287920157 0.0006386483653524 +Phosphatidylcholine binding 2 8 2.4503015063167424 0.0142736637124956 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0385296980798545 1.0 0.1432798584585485 0.0062267265321947 0.039942155971048 +Lipid binding 54 157 2.4479852130631765 0.0143657551176363 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0158773782963301 0.630971068815132 0.2627093960643603 0.0063235077949935 0.0067461008028442 +Oxidoreductase activity acting on a heme group of donors 4 7 2.3994185609169696 0.0164211321367782 3.111650485436894 6.483009708737864 0.8850005512180296 0.2757097651603665 1.538237610319269 1.0226572421183926 1.2777814224392188 0.2966482201944345 0.0005000280862091 1.0 0.1349531130589082 0.0051503840765812 0.0005338561483377 +Udp glycosyltransferase activity 12 22 2.3910111454709995 0.0168020428080024 5.111650485436893 16.645631067961165 0.3599735227181602 0.3819150449260511 2.50187506268716 3.5246228662547776 1.2344018614792536 0.2994506580113357 0.1499165482828329 1.0 1.0 0.1083386684032722 0.1570895071582956 +Cation channel activity 7 21 2.372883525633381 0.0176498286806041 6.628640776699029 20.20145631067961 0.2168681550185727 0.4203796109119975 3.66569707500714 2.3934980322982335 1.245793992642405 0.316602380113191 0.0636312299406509 0.0473022522201117 0.1588529428511447 0.2664860397703889 0.0676022626142099 +Ceramide binding 4 5 2.3543466690705075 0.018555297122951 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0002321391353102 1.0 0.0066572828402184 0.003355333516566 0.0002481332774246 +O acyltransferase activity 7 14 2.335745694932682 0.0195044994176807 4.711165048543689 12.395631067961164 0.9877600518928406 0.2684789023147002 2.6842893514436073 2.3496085895491885 1.2379749168209273 0.2720543739153138 0.0171326261044573 1.0 1.0 0.0415700360883472 0.0181161163925661 +Solute cation symporter activity 8 10 2.3125995294518167 0.0207446674313189 2.854368932038835 7.206310679611651 0.8639239563858236 0.3319920905256767 1.9640347167867271 2.0653542869596597 1.117186698589392 0.3146562336443082 0.0194194773536838 1.0 0.2732850813359189 0.0449350347407693 0.0205229364106292 +Protein carrier chaperone 5 12 2.312284553272175 0.0207620073552385 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 0.0012658498659003 1.0 1.0 0.0007869115437374 0.0013491401517078 +Sphingolipid binding 5 6 2.3119163165062666 0.0207822953755276 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0012658498659003 1.0 0.0126574737404708 0.0087554356838108 0.0013491401517078 +Sodium ion transmembrane transporter activity 6 8 2.2912021601201475 0.0219517240956648 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.3005729845571436 1.0 1.0 0.6257540014635683 0.3081896593873433 +Molecular carrier activity 22 38 2.2844041635724204 0.0223477891074075 8.985436893203884 32.922330097087375 0.4263347027610819 0.5995318029338973 4.267144921372851 3.1428430650945036 0.9199841946557948 0.3455794463799358 0.0055060029158712 1.0 0.4242240140575919 0.000423196822916 0.0059899182032361 +Inorganic anion transmembrane transporter activity 15 25 2.27922461647361 0.0226537164995348 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 0.0001506806965379 0.2180755491779121 0.0135419734012732 0.0015231541907095 3.176403402652151e-05 +Glycolipid binding 7 10 2.276572859314715 0.0228117451458944 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 9.285534997667568e-05 0.0771453392642774 0.0005309775927247 0.0074273483269255 0.0001004910149917 +Growth factor receptor binding 4 16 2.2748076068907124 0.0229174737156128 5.233009708737864 16.303398058252426 0.6012049824390195 0.4932334837741021 2.455245557470486 2.477606131434232 0.8745174126419827 0.327387299755004 0.2699756070459421 1.0 1.0 0.3863305945153184 0.1280001064666262 +Voltage gated anion channel activity 4 7 2.274158756781448 0.0229564429932156 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0008708072207696 1.0 0.0921025797166938 0.001485709034831 5.489393781591606e-05 +Lamin binding 6 9 2.2595125884678025 0.0238515181465697 3.174757281553398 8.133495145631068 0.8401140072225439 0.3634406451484216 1.8429987407927015 0.9675032512806204 0.9823145131994128 0.293984725882831 0.0324301480805536 1.0 1.0 0.307957256786686 0.0336357980244025 +Peptide antigen binding 5 6 2.258723536301678 0.0239005874659359 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.0005000280862091 0.0683810764565047 0.1349531130589082 0.0498779046475234 0.0005338561483377 +Exogenous protein binding 6 16 2.2494233437776665 0.0244855748013248 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.0628856072356096 1.0 1.0 0.0949405615621671 0.0660317196551079 +Sodium channel regulator activity 3 5 2.2077110505944524 0.0272644220153974 1.2742718446601942 3.6966019417475726 0.3480048328963068 0.4818068972424751 1.0072640073334362 1.4951988232878188 1.029255998785111 0.3156490188407561 0.0046737877195888 0.0683810764565047 0.0088504827764808 0.0051503840765812 0.0049176108076387 +Scavenger receptor activity 5 6 2.179628853505461 0.0292849842225646 2.128640776699029 4.245145631067961 0.8895147156183107 0.1752904943890176 1.2029313295363038 0.9324780265795692 1.5451274177295422 0.2106852326062687 0.0019008813135546 1.0 1.0 0.0328731354880699 0.0020033682110678 +Amino acid transmembrane transporter activity 9 11 2.1753301002016423 0.0296053884541716 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.1233990224640946 1.0 1.0 0.0720513532108381 0.1281606076495765 +Acylglycerol o acyltransferase activity 4 8 2.1696210888868817 0.0300355624344625 2.6601941747572817 6.820388349514563 0.8174935736497821 0.2734948556707107 1.708365471336677 1.514259678343348 1.2372108727630755 0.2654117957889352 0.0768164760449794 1.0 1.0 0.4028006685093745 0.0794376465838621 +Serine type exopeptidase activity 5 7 2.1322587819338046 0.0329855784953265 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 0.0005429904047299 1.0 6.936272072908627e-05 0.0010588751859522 0.0005732271800539 +Quaternary ammonium group binding 3 13 2.119571582697226 0.0340421910859125 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0192115706028201 1.0 0.191600110602388 0.0017432511761074 0.0201372619620155 +Dicarboxylic acid transmembrane transporter activity 5 8 2.1191927251237006 0.0340741828548845 2.842233009708738 7.20873786407767 1.0708946030323223 0.2426579907451208 1.9772646753006824 0.7975212565102757 1.0844681659651012 0.2564515003952125 0.0385296980798545 1.0 0.1432798584585485 0.0561137872346343 0.039942155971048 +Atp transmembrane transporter activity 4 5 2.099810168252143 0.0357455434202726 3.058252427184466 5.456310679611651 0.5680189081478334 0.3318090311699867 1.598392655736251 0.6936144116307477 1.3025695117924114 0.3140848719976767 0.0003135208860554 1.0 1.0 0.1781979724676324 0.0003311660608568 +P type transmembrane transporter activity 5 7 2.0738491641606407 0.0380933215295182 2.842233009708738 5.473300970873787 0.6050493013674468 0.3730987003611934 1.6045635356324264 1.3712604140019378 1.17652933932801 0.3174788438558891 0.0174422350800748 1.0 1.0 1.0 0.0181181417645757 +L amino acid transmembrane transporter activity 6 9 2.0514496183126227 0.040223181234503 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.160353317011437 1.0 1.0 0.1552222190730896 0.1652047572335966 +Quinone binding 2 5 2.044658578088026 0.040888530024671 2.0825242718446604 5.371359223300971 0.6144040024425256 0.3400691378536611 1.308295206174148 0.7946759106689059 1.1785397932704846 0.300626350021166 0.0218821422536325 1.0 0.1180585699575878 0.0382400085743442 0.0227185425065092 +Channel regulator activity 7 18 2.041629772416356 0.0411882697312622 4.783980582524272 15.990291262135925 0.0369609692667819 0.5929843198395084 2.4023523422516506 2.637464013028564 0.8201394905149542 0.2901418796271611 0.0202624952873958 0.2400196775334175 0.0181443698350236 0.0129296559640097 0.0217195139585283 +Fad binding 7 10 2.0382215279466807 0.0415277834883327 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.3565095703047432 1.0 1.0 0.4718643991127431 0.3630866560691931 +Iron ion binding 8 26 2.035883289039737 0.0417620762445907 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.0260303627734288 0.2507644527164699 0.0207328276809773 0.0600215848699845 0.0278547210480151 +Protease binding 14 35 2.035165593679774 0.0418342137451939 6.186893203883495 26.72087378640777 0.4143971461280679 0.5282949986204084 3.052378200340675 3.815814208193157 0.8315156489156551 0.2995827216567743 0.012996745876787 1.0 0.5351022899588459 0.0424479309650379 0.014156638351275 +Membrane insertase activity 4 9 2.021760894145499 0.0432010595556255 2.737864077669903 7.388349514563107 0.8099367695235317 0.306513025583228 1.5809003521008822 1.7333564146948666 1.2685525479217892 0.3048480656363501 0.00356078515082 1.0 1.0 0.0041946485896371 0.0037486095651754 +Metalloendopeptidase activity 10 15 1.999723517364845 0.0455301272813166 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.0713523815072877 1.0 0.2732850813359189 0.0449350347407693 0.0743636419116672 +Sterol transporter activity 3 11 1.9653777744701617 0.049370529929235 2.621359223300971 8.364077669902912 0.5454888897585024 0.2973249899153176 1.425267849835305 1.6080715320593837 1.318674977748992 0.2709274408896192 0.022397770973718 1.0 1.0 0.4314443861210575 0.0234644839392777 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e662946c7ff1bbe5a6c59ff351b64f91cfcf7f22 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 1415, + "title": "Average number of proteins per term", + "value": 17.903180212014135 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d24e96210708e6075d415896a8fbd3304413513f --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..624edcc2e0f9819f3e41e0df4b1d3ae3809f0bd0 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,425 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.6088140833985486 7.61594266488228 2.6177387589570563e-14 3.7042418438556765e-11 3.704241843924235e-11 202 Q9UDW1,P06756,O60830,P36543,Q9NS69,Q99595,O75027,O14678,P00846,O43676,Q9C0H2,Q9HC07,P17900,O75964,Q9Y584,O43808,Q9H2D1,O14925,Q96ES6,Q7L0J3,O15173,P03886,Q13423,P13073,Q9UBX3,P21796,Q9H2V7,P45880,Q9BSK2,Q70HW3,Q9P0J0,P08183,Q7KZN9,P33527,P24539,P33897,Q9H2J7,Q8N4V1,P53985,Q9NP58,Q8TAD4,O00400,O15439,P05023,Q9H2C2,Q8TB61,P98164,P04062,P00403,Q9Y5J9,Q8WTV0,Q9H9B4,Q96QD8,Q9Y277,Q9HD20,O75746,Q8N1S5,O43681,Q9Y6M9,Q07820,P51970,P12235,Q9Y619,Q04656,P20674,O95563,P51797,Q8NE01,Q15388,L0R6Q1,P61916,Q9UJS0,Q9NUT2,Q9Y6M7,Q9Y255,Q14849,Q9UM00,Q9Y5J6,P38435,O95139,P51798,P55011,O95168,P12236,Q03518,O15118,O95202,Q9NW15,Q9BQT8,O96000,Q6P4Q7,P30825,P30536,Q9NV96,Q96AA3,Q93050,P23634,P56385,O14548,Q15043,P20020,Q96RD7,P06576,P05141,P16615,Q9HC21,P49755,Q9Y487,Q6NUK1,Q9NWR8,P51790,Q99758,Q96S66 113 +Proton transmembrane transporter activity 0.6587610314236808 4.104588222984516 4.0503568182526095e-05 0.0557022124714126 0.0114625097956551 40 Q9UDW1,Q93050,P00846,O00400,P56385,O14548,O75964,P00403,Q96ES6,P06576,O95202,P05141,Q13423,P13073,Q9Y487,P12235,P51790,Q7KZN9,P24539 19 +Organic anion transmembrane transporter activity 0.6822871827315894 4.041109517596076 5.319890520349979e-05 0.072514810893483 0.0117812641849329 33 P53985,Q9Y6M7,O00400,O15439,Q8TB61,P12236,Q9H2D1,O43808,Q9H9B4,Q96QD8,P05141,O75746,Q9HC21,Q9UBX3,Q9BQT8,P12235,Q6NUK1,Q9Y619,O95563,P30825,P33527 21 +Ion transmembrane transporter activity 0.60146040383143 4.019661283690597 5.828187229295345e-05 0.0791620908347755 0.0117812641849329 117 Q9UDW1,P06756,P36543,Q9H2J7,Q93050,Q9UJS0,Q8N4V1,P53985,Q9Y6M7,P00846,Q8TAD4,Q9C0H2,O00400,Q9UM00,O15439,Q9HC07,P05023,P55011,P23634,P56385,O14548,Q8TB61,O75964,O43808,Q9H2D1,P00403,P12236,Q15043,P20020,Q9H9B4,Q96RD7,Q96QD8,Q96ES6,O95202,Q9Y277,P06576,P05141,Q9HD20,O75746,P16615,Q8N1S5,Q9HC21,O43681,Q9NW15,Q13423,P13073,Q9UBX3,P21796,Q9Y487,Q9BQT8,P12235,Q6NUK1,Q9Y619,P45880,P51797,Q04656,P20674,O95563,Q6P4Q7,P30825,Q9NWR8,Q70HW3,P51790,Q7KZN9,P33527,Q96S66,P24539 67 +Active ion transmembrane transporter activity 0.6469998576766254 3.95182245555798 7.755827510536051e-05 0.103941175043496 0.0126798632329896 51 Q9UDW1,Q9H2J7,P36543,Q9H936,Q9Y6M7,P23634,O00400,O15439,P55011,P05023,P51798,O14548,Q02978,P00403,Q15043,P12236,P20020,P05026,Q96QD8,Q96ES6,O95202,P05141,P06576,Q9HD20,P16615,P13073,P12235,Q9Y5K8,P51797,Q04656,P20674,P51790,P04920,Q7KZN9,P33527 35 +Cation transmembrane transporter activity 0.6399902995987684 3.931667594298448 8.435865554101696e-05 0.1125228750904284 0.0126798632329896 81 Q9UDW1,P06756,P36543,Q9H2J7,Q93050,Q8N4V1,Q9Y6M7,P00846,Q8TAD4,P23634,O00400,Q9HC07,P56385,O14548,O75964,P00403,Q15043,P20020,Q96RD7,Q96ES6,O95202,P06576,P05141,Q9HD20,P16615,Q8N1S5,Q9HC21,Q9NW15,Q13423,P13073,Q9Y487,P12235,Q9Y619,Q6P4Q7,P30825,Q70HW3,P51790,Q7KZN9,P24539 39 +Metal ion transmembrane transporter activity 0.6780395255193131 3.917127551469828 8.961034086918396e-05 0.1190939632044401 0.0126798632329896 31 P06756,Q9H2J7,Q8N4V1,Q9Y6M7,Q9UM00,Q8TAD4,P23634,Q9HC07,P55011,P05023,Q15043,P20020,Q96RD7,Q96QD8,O95202,Q9HD20,P16615,Q8N1S5,Q6P4Q7,Q04656 20 +Steroid binding 0.7305085731607798 3.8179655187506114 0.0001345567261592 0.1733803278515619 0.0173088879559402 23 O15173,P45880,O00264,P04062,Q14849,Q14108,P21796,O15118,O95772,P38435 10 +Molecular transducer activity 0.6165408785699926 3.760473950646869 0.0001695917352382 0.2133663621712003 0.0185710126751909 38 P06756,Q5KU26,Q15629,O75787,Q92859,P10586,P49327,Q9BUN8,Q07954,Q00688,Q8WTV0,O15118,Q15375,O15173,O15031,P11717,Q08722,Q99720,P30536,Q9NRA0,Q14108 21 +Secondary active transmembrane transporter activity 0.6824048309805681 3.7589659143115295 0.0001706170775812 0.2145070233529667 0.0185710126751909 26 Q9H2J7,Q9H936,P53985,Q9Y6M7,O00400,P55011,P51798,Q02978,P12236,Q15043,Q96QD8,Q96ES6,O95202,P05141,Q9UBX3,P12235,P51790,P04920,P51797 19 +Atpase coupled transmembrane transporter activity 0.6406057771522061 3.665885243372118 0.0002464844455325 0.294478816106513 0.0232516993619036 32 Q15388,P33897,P36543,Q9NUT2,Q9NP58,O75027,O14678,P23634,O15439,P05023,P51798,P20020,Q03518,P05026,P06576,Q9HD20,P16615,P51797,Q04656,Q99758,P08183,P33527 22 +Protein transporter activity 0.7893515596003229 3.616777572901632 0.0002982934174133 0.3443631009186911 0.025617907427081 17 Q9HD20,Q15388,O60830,Q9NS69,Q9Y584,Q9Y5J9,Q99595,O14925,Q07820 9 +Inorganic molecular entity transmembrane transporter activity 0.5984530118590502 3.6086647959935583 0.0003077769796893 0.3531051125606065 0.025617907427081 92 Q9UDW1,P06756,Q9H2J7,Q93050,Q8N4V1,Q9Y6M7,P00846,Q8TAD4,Q9C0H2,O00400,P23634,Q9HC07,P56385,O14548,O75964,P00403,Q15043,P20020,Q96RD7,Q96ES6,O95202,Q9Y277,P06576,P05141,Q9HD20,P16615,Q8N1S5,Q9NW15,Q13423,P13073,Q9UBX3,P21796,Q9Y487,P12235,P45880,P51797,Q6P4Q7,Q9NWR8,P51790,Q7KZN9,P33527,Q96S66,P24539 43 +Nucleobase containing compound transmembrane transporter activity 0.7835613166395721 3.582438923038119 0.000340401219971 0.3822983623073563 0.0263490278109465 17 Q6NUK1,P33897,Q9BSK2,L0R6Q1,Q8TB61,Q9HC21,P12236,Q9H2D1,O43808,O00400,P05141,P12235 12 +Lipid transporter activity 0.6430057044063021 3.5293352327008924 0.0004166050351641 0.4454614499350208 0.0280712440360615 28 Q9H2C2,P33527,P33897,P17900,P30536,Q9Y255,Q99758,Q9NV96,O14678,Q14849,P08183,O15118,Q96AA3 13 +Organic acid transmembrane transporter activity 0.6636695742388913 3.46428488886285 0.0005316431490867 0.528801154983542 0.0318411939523471 24 Q9Y619,P33527,O75746,Q9H2J7,O95563,P30825,P53985,Q9H2D1,Q9H9B4,Q9UBX3,P08183,Q96QD8,Q9BQT8,O15439 14 +Tetrapyrrole binding 0.747657990589296 3.439865581607899 0.000582003165112 0.5612274991354821 0.0318411939523471 18 O43169,Q16850,O15173,P09601,O00264,Q9H7Z7,Q7KZN9,P30519,Q6UW02 9 +Nucleotide transmembrane transporter activity 0.7858477526831521 3.4151265037615004 0.000637523953193 0.5943984763064227 0.0322177283488632 15 Q6NUK1,P33897,Q9BSK2,Q8TB61,Q9HC21,P12236,Q9H2D1,O43808,O00400,P05141,P12235 11 +Organophosphate ester transmembrane transporter activity 0.7858477526831521 3.4151265037615004 0.000637523953193 0.5943984763064227 0.0322177283488632 15 Q6NUK1,P33897,Q9BSK2,Q8TB61,Q9HC21,P12236,Q9H2D1,O43808,O00400,P05141,P12235 11 +Active transmembrane transporter activity 0.5763919060186443 3.348065127794179 0.0008137788498279 0.683985082373596 0.0375133089453347 88 Q15388,Q9UDW1,P33897,P36543,Q9H2J7,Q9NUT2,P53985,Q9Y6M7,Q9NP58,O75027,O14678,O43676,P23634,O00400,O15439,P05023,P55011,P51798,O95139,O95168,O14548,P00403,P12236,Q15043,P20020,Q03518,Q96QD8,Q96ES6,O95202,P06576,P05141,Q9HD20,P16615,P03886,P13073,Q9UBX3,Q9Y6M9,P51970,O96000,P12235,P51797,Q04656,P20674,P51790,Q9P0J0,Q99758,P08183,Q7KZN9,P33527 49 +Anion transmembrane transporter activity 0.5787069110782218 3.3344148597265293 0.0008547906422846 0.7018164374910048 0.037797773713525 52 Q9UJS0,P53985,Q9Y6M7,Q9C0H2,O00400,O15439,P55011,Q8TB61,P12236,Q15043,Q9H2D1,O43808,Q9H9B4,Q96QD8,Q9Y277,P05141,O75746,Q9HC21,O43681,Q9NW15,Q9UBX3,P21796,Q9BQT8,P12235,Q6NUK1,Q9Y619,P45880,P51797,O95563,P30825,P51790,P33527,Q96S66 33 +Macromolecule transmembrane transporter activity 0.8043634698850337 3.2721584337024963 0.0010672974865328 0.779317982301875 0.0457644225286073 13 O60830,Q9NS69,Q9Y584,Q99595,O14925,Q07820 6 +Snap receptor activity 0.7297079945108964 3.1677867889131575 0.0015360412561356 0.8864110876933544 0.0620999536409107 16 O95249,O43752,O14653,Q12981,O60499,O15498,Q9P2W9,O15400,O95721,Q86Y82,Q13190 11 +Protein transmembrane transporter activity 0.808561247346362 3.142271258063852 0.0016764264536224 0.9069049271129492 0.0658928731076592 12 O60830,Q9NS69,Q9Y584,Q99595,O14925,Q07820 6 +Carbohydrate derivative transmembrane transporter activity 0.8062500616980264 3.1299740572579218 0.0017482174157885 0.9159120894850862 0.0668575038740763 12 Q6NUK1,P33897,L0R6Q1,Q8TB61,P12236,O00400,P05141,P12235 8 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.563102084839376 3.1020271737713543 0.0019220031454172 0.9342733876856436 0.0715693276517209 34 P07237,Q9C0B1,Q16850,P16435,O75845,P09601,Q8NB78,Q32P28,Q14534,O15460,P30519,P13674,Q15800,Q6UW02 14 +Sterol binding 0.6884435172384149 3.0648944756564593 0.0021774680980954 0.9542460317683782 0.0770651865439593 18 P45880,Q14108,Q14849,P21796,O15118,O95772 6 +Primary active transmembrane transporter activity 0.5521867505203109 3.04214307027612 0.0023490021696095 0.9641261996665488 0.0772985597673836 64 Q15388,Q9UDW1,P33897,P36543,Q9NUT2,Q9NP58,O75027,O14678,O43676,P23634,O15439,P05023,P51798,O95139,O95168,O14548,P00403,P20020,Q03518,P06576,Q9HD20,P16615,P03886,P13073,Q9Y6M9,P51970,O96000,P33527,Q04656,P20674,Q9P0J0,Q99758,P08183,Q7KZN9,P51797 35 +Passive transmembrane transporter activity 0.5365454011623016 3.0349906018197705 0.0024054318237216 0.9668855744550536 0.0773565006946852 39 P45880,P56385,P51797,Q9NWR8,O75964,Q9NW15,P51790,P00846,P21796,Q96RD7,Q9C0H2,P06576,Q9Y277,Q96S66,P24539 15 +Cholesterol binding 0.7188857184074416 3.0214087615302607 0.002516014527546 0.9716930179963418 0.077707620204374 15 P45880,Q14108,Q14849,P21796,O15118,O95772 6 +Hexosyltransferase activity 0.5318471065028597 3.0008697876156107 0.0026920965802468 0.97795023657948 0.0793668277200977 38 Q2TAA5,Q10471,P04843,O60762,Q16880,P46977,Q8NBJ5,P04062,Q13126,Q9NYU2,Q16739,P06865,Q6ZXV5,Q8N4A0,P15291,Q9BT22,O43505,P26572,Q10472,P04844,P07686 21 +Abc type transporter activity 0.7547075002168047 2.996768132968178 0.0027285816239754 0.9790626377476528 0.0793668277200977 13 Q9HD20,P33897,Q99758,O75027,Q03518,O14678,P08183,Q9NP58,P33527,O15439 10 +Atpase binding 0.5715031992959985 2.98903562718579 0.0027985949707627 0.981042648457632 0.0793668277200977 29 Q92542,Q9Y487,P36543,Q93050,Q16740,Q9BUN8,P11233,Q86TM6,Q5JTV8,O76024,P40855 11 +Monooxygenase activity 0.8692667123587771 2.988393572884794 0.0028044815448797 0.9812003378837992 0.0793668277200977 8 Q16850,P09601,P30519,Q15800,Q6UW02 5 +Signal sequence binding 0.5633433548750436 2.9535477720022816 0.0031414398212747 0.9883463293328492 0.0866074833073756 30 Q15388,P24390,Q9Y584,Q92973,O43731,P40855,P52292 7 +Purine nucleotide transmembrane transporter activity 0.772719432103023 2.9495133226569616 0.0031827485031685 0.9890100193483736 0.0866074833073756 12 Q6NUK1,P33897,Q8TB61,P12236,O43808,O00400,P05141,P12235 8 +Hydrolase activity hydrolyzing o glycosyl compounds 0.5878974698879529 2.89247379595903 0.0038222106447158 0.995567495706757 0.099933695149134 24 P08236,P17900,P10253,O00754,P04062,P54802,Q9BTY2,O60476,P06865,P06280,P16278 11 +Alcohol binding 0.6574568920632049 2.7985672271324744 0.005132988300093 0.9993121112166709 0.1171480394295421 17 P45880,O14735,P61916,P30536,O94905,Q14108,Q14849,P21796,O15118,O95772 10 +Cargo receptor activity 0.7742215576021982 2.779001980627622 0.0054526192635637 0.9995634325882476 0.1224675596498847 11 O15260,Q08380,Q5JRA6,Q5KU26,P98164,Q07954,Q14108,P22413,Q8WTV0 9 +Sulfur compound transmembrane transporter activity 0.7912407676519488 2.6795027734187618 0.0073731592459818 0.9999716723614678 0.140771612919809 9 P33897,Q70HW3,Q9UBX3,P33527,O00400 5 +Transition metal ion transmembrane transporter activity 0.8019614263821383 2.662701102363105 0.0077516235091339 0.9999834856402312 0.141293129511808 8 Q9HD20,Q8N1S5,Q8N4V1,Q8TAD4,Q9HC07 5 +Vitamin transmembrane transporter activity 0.847246632242938 2.66106675154045 0.0077893513104643 0.999984350681375 0.141293129511808 7 Q9HC21,P04062,Q9H2D1,P33527,P38435 5 +Fk506 binding 0.8403844466662934 2.629074121602924 0.0085617697182105 0.9999948011057448 0.1425282841325638 7 Q9Y680,P26885,Q02790,Q96AY3,P62942 5 +Macrolide binding 0.8403844466662934 2.629074121602924 0.0085617697182105 0.9999948011057448 0.1425282841325638 7 Q9Y680,P26885,Q02790,Q96AY3,P62942 5 +Serine hydrolase activity 0.5903739422526031 2.6222512439495453 0.008735100954258 0.9999959405698436 0.1429911068413526 21 P42785,Q16740,Q6PIU2,P67812,Q9HB40,Q6NTF9,Q9H300,Q2T9J0,Q9H3G5,Q5JRX3,O14773,O75976,P10619 13 +Amide transmembrane transporter activity 0.8376198175547028 2.6161505769372937 0.0088927331463173 0.999996758586066 0.1429911068413526 7 P33527,O00400,P33897,Q9H2D1 4 +Hydrolase activity acting on glycosyl bonds 0.5199670366481679 2.611167971393785 0.0090233561726671 0.9999973100910224 0.1432012483257166 31 P08236,P17900,P10253,O00754,P04062,P54802,Q9BTY2,O60476,P06865,P06280,O75503,P16278 12 +Antiporter activity 0.7080364926195835 2.590144771981133 0.0095935576905357 0.9999988086451032 0.1475530883924787 12 P12236,P51790,P51798,P04920,Q9UBX3,P51797,O95202,P05141,P12235 9 +Symporter activity 0.6974804633247779 2.5300441290010136 0.0114048181606603 0.9999999106359944 0.1595801052359212 12 Q9H2J7,Q9H936,P53985,Q15043,Q9Y6M7,Q96QD8,O00400,Q96ES6,P55011 9 +Calcium ion transmembrane transporter activity 0.6268031933309584 2.5194593392399964 0.0117535214538611 0.999999945754364 0.1595801052359212 16 P16615,P20020,Q96RD7,P23634,O95202,Q9HC07 6 +Oxidoreduction driven active transmembrane transporter activity 0.505845569099546 2.51734180475433 0.0118244055884886 0.9999999509899712 0.1595801052359212 32 O95139,Q9UDW1,P03886,P00403,Q9P0J0,P13073,Q7KZN9,O43676,O96000 9 +Antigen binding 0.7699391253045149 2.5031905269483716 0.0123079266980523 0.9999999754800696 0.1621656404878417 8 P30153,P55899,P10321,Q03518,P04439,Q15392 6 +Phosphatidylcholine binding 0.759452714992008 2.4503015063167424 0.0142736637124956 0.9999999985369828 0.1722673177241989 8 P45880,P21796 2 +Lipid binding 0.3965760310057266 2.4479852130631765 0.0143657551176363 0.9999999987181576 0.1722673177241989 157 Q9BQE5,Q9H4A6,Q13045,O00264,P61916,Q9NZJ7,P28070,Q01082,P50897,Q14849,Q9H490,Q96E52,P05023,Q08431,P38435,Q9BWH2,Q92643,A6NIH7,O15020,P04062,O43292,Q8WTV0,Q9NQZ5,O14773,O15118,P07602,Q8NFH5,Q9Y371,O15173,P53365,Q99623,O75208,Q96D53,O60313,P11717,Q9UJZ1,P21796,Q9UM22,A0FGR8,O14735,P45880,Q8NCC3,P30536,O00429,O00560,Q15067,Q99584,Q96L92,Q9Y3E7,Q14108,O14964,Q86YQ8,Q06481,O95772 54 +Oxidoreductase activity acting on a heme group of donors 0.7918754945054947 2.3994185609169696 0.0164211321367782 0.9999999999331652 0.1821122025880623 7 Q7KZN9,P16435,P13073,P00403 4 +Udp glycosyltransferase activity 0.5484423707366146 2.3910111454709995 0.0168020428080024 0.999999999961366 0.1821122025880623 22 P15291,Q10472,Q10471,Q9NYU2,Q16739,Q16880,O43505,P06865,P07686,Q8NBJ5,P26572,Q8N4A0 12 +Cation channel activity 0.556973329138964 2.372883525633381 0.0176498286806041 0.9999999999886016 0.1863769222616036 21 P56385,O75964,Q9NW15,P00846,Q96RD7,P06576,P24539 7 +Ceramide binding 0.903781038374712 2.3543466690705075 0.018555297122951 0.9999999999969086 0.1930569516836447 5 Q9NZJ7,P45880,P07602,P21796 4 +O acyltransferase activity 0.6191460785569963 2.335745694932682 0.0195044994176807 0.999999999999214 0.1971347619715588 14 Q96N66,P23786,Q8NCC3,Q92604,Q9HCL2,Q8NF37,P50416 7 +Solute cation symporter activity 0.7159537404171569 2.3125995294518167 0.0207446674313189 0.9999999999998688 0.2014174517559702 10 Q9H2J7,Q9H936,Q15043,Q9Y6M7,Q96QD8,O00400,Q96ES6,P55011 8 +Protein carrier chaperone 0.6598300220456089 2.312284553272175 0.0207620073552385 0.999999999999872 0.2014174517559702 12 Q8N4V1,Q9NPA0,Q15070,P40855,Q8N8Q8 5 +Sphingolipid binding 0.8371436635619663 2.3119163165062666 0.0207822953755276 0.9999999999998758 0.2014174517559702 6 P45880,Q9NZJ7,P21796,Q9UM22,P07602 5 +Sodium ion transmembrane transporter activity 0.7282886968789407 2.2912021601201475 0.0219517240956648 0.9999999999999772 0.2017600424559014 8 Q6P4Q7,Q9H2J7,Q9Y6M7,P55011,Q96QD8,P05023 6 +Molecular carrier activity 0.4578680725841598 2.2844041635724204 0.0223477891074075 0.9999999999999872 0.2017600424559014 38 O75880,Q8N4V1,Q8TEX9,Q15070,O15504,Q8N8Q8,Q9Y5L0,P52292,P55060,O43819,Q9P0I2,Q15006,Q9C0E2,Q53FT3,Q96P70,Q8N766,O60518,Q5J8M3,Q04656,Q9NPA0,Q92973,P40855 22 +Inorganic anion transmembrane transporter activity 0.4998397814966374 2.27922461647361 0.0226537164995348 0.9999999999999916 0.2017600424559014 25 P33527,P45880,P51797,Q96S66,O43681,Q9NW15,Q15043,Q9Y6M7,P51790,Q9UBX3,P21796,Q9C0H2,O15439,Q9Y277,P55011 15 +Glycolipid binding 0.7092019012424853 2.276572859314715 0.0228117451458944 0.9999999999999934 0.2017600424559014 10 Q9NZJ7,O43292,P50897,Q9UM22,O14773,Q9H490,P07602 7 +Growth factor receptor binding 0.5898897523511306 2.2748076068907124 0.0229174737156128 0.9999999999999944 0.2017600424559014 16 Q92542,P05067,Q9H2J4,Q9NZ08 4 +Voltage gated anion channel activity 0.7659538021930647 2.274158756781448 0.0229564429932156 0.9999999999999948 0.2017600424559014 7 P51797,P45880,Q9Y277,P21796 4 +Lamin binding 0.7098823427750667 2.2595125884678025 0.0238515181465697 0.9999999999999986 0.2062154345384106 9 Q5SNT2,Q9UH99,P42167,Q14739,Q5JTV8,O94901 6 +Peptide antigen binding 0.8252893028506947 2.258723536301678 0.0239005874659359 0.9999999999999988 0.2062154345384106 6 P55899,P10321,Q03518,P04439,Q15392 5 +Exogenous protein binding 0.5861154192358315 2.2494233437776665 0.0244855748013248 0.9999999999999994 0.2087173996618955 16 P06756,Q8WTV0,Q14108,P11279,O15118,P35613 6 +Sodium channel regulator activity 0.8691231403538611 2.2077110505944524 0.0272644220153974 1.0 0.218968136101771 5 Q96PU5,P46934,Q9HD47 3 +Scavenger receptor activity 0.8077900084674101 2.179628853505461 0.0292849842225646 1.0 0.2206739871137601 6 Q08380,Q5KU26,Q8WTV0,Q14108,P22413 5 +Amino acid transmembrane transporter activity 0.6638835513074235 2.1753301002016423 0.0296053884541716 1.0 0.2206739871137601 11 Q9Y619,Q96NB2,O75746,Q9H2J7,P30825,Q9UJS0,Q9H936,Q9H9B4,Q96QD8 9 +Acylglycerol o acyltransferase activity 0.7048455025270198 2.1696210888868817 0.0300355624344625 1.0 0.2213558377331488 8 Q96N66,Q92604,Q8NF37,Q8NCC3 4 +Serine type exopeptidase activity 0.7370219221215318 2.1322587819338046 0.0329855784953265 1.0 0.2338166644517467 7 Q9HB40,P10619,O14773,O75976,P42785 5 +Quaternary ammonium group binding 0.6067229438480725 2.119571582697226 0.0340421910859125 1.0 0.2355534264377061 13 Q14108,P45880,P21796 3 +Dicarboxylic acid transmembrane transporter activity 0.6952126275258659 2.1191927251237006 0.0340741828548845 1.0 0.2355534264377061 8 O75746,Q9UJS0,Q9H936,Q9UBX3,Q9BQT8 5 +Atp transmembrane transporter activity 0.8439616252821611 2.099810168252143 0.0357455434202726 1.0 0.2428809396085896 5 Q6NUK1,P12235,P12236,P05141 4 +P type transmembrane transporter activity 0.7252409338663109 2.0738491641606407 0.0380933215295182 1.0 0.2516369610424796 7 P16615,Q04656,P20020,P23634,P05023 5 +L amino acid transmembrane transporter activity 0.6709734917887085 2.0514496183126227 0.040223181234503 1.0 0.2575375631077912 9 Q9Y619,O75746,P30825,Q9UJS0,Q9H9B4,Q96QD8 6 +Quinone binding 0.831207221121708 2.044658578088026 0.040888530024671 1.0 0.2606183332653584 5 Q8N0U8,Q16134 2 +Channel regulator activity 0.5390174415119018 2.041629772416356 0.0411882697312622 1.0 0.2608897067883424 18 P46934,Q13586,Q9NWR8,Q96PU5,Q9HD47,P23634,P62942 7 +Fad binding 0.6651873680928813 2.0382215279466807 0.0415277834883327 1.0 0.2608897067883424 10 O15254,Q8NB78,Q15067,Q14534,O95831,Q15392,Q96HE7 7 +Iron ion binding 0.4696502876645557 2.035883289039737 0.0417620762445907 1.0 0.2608897067883424 26 P22830,Q16850,O75845,Q32P28,O15460,P13674,Q15800,Q6UW02 8 +Protease binding 0.4442187717443152 2.035165593679774 0.0418342137451939 1.0 0.2608897067883424 35 P06756,Q9GZP9,Q13586,Q13438,Q9NZJ7,Q9BUN8,P46379,Q96RR1,Q9Y3E7,Q86TM6,Q2T9J0,Q96RD7,O75955,P07602 14 +Membrane insertase activity 0.665490872632531 2.021760894145499 0.0432010595556255 1.0 0.2634892209965957 9 Q15070,Q8N8Q8,Q8N4V1,Q9NPA0 4 +Metalloendopeptidase activity 0.5585894954554199 1.999723517364845 0.0455301272813166 1.0 0.2729878394197588 15 O75844,Q10713,Q96TA2,Q92905,Q9BYT8,P22695,P42892,Q5JRX3,Q9Y4W6,Q96E52 10 +Sterol transporter activity 0.6271872600168789 1.9653777744701617 0.049370529929235 1.0 0.2874868306578915 11 Q9H2C2,O15118,Q14849 3 +Mhc protein binding 0.6529838759422515 1.9536986821174749 0.0507368622579214 1.0 0.2924919601991856 9 Q03518,P06576,Q9NUQ9,Q9BUN8 4 +Anion channel activity 0.5600430590147663 1.9527418471908864 0.0508501923738513 1.0 0.2924919601991856 14 P45880,P51797,Q9NW15,P51790,P21796,Q9C0H2,Q9Y277 7 +Porin activity 0.8614935573254678 1.9383644582925104 0.0525787734026899 1.0 0.2955883192770253 4 P45880,P21796 2 +Serine type carboxypeptidase activity 0.8050225733634159 1.9304938360978596 0.0535456782196519 1.0 0.2955883192770253 5 Q9HB40,P42785,O75976,P10619 4 +Xenobiotic transmembrane transporter activity 0.8039402592052088 1.9257483353813416 0.0541358053372862 1.0 0.2955883192770253 5 Q99758,P08183,P33527 3 +Peptidyl proline dioxygenase activity 0.8038389946201799 1.9253042256733424 0.0541913093080288 1.0 0.2955883192770253 5 P13674,P07237,Q32P28 3 +Proton channel activity 0.6201288472070488 1.9244826315632737 0.0542941157336804 1.0 0.2955883192770253 11 O75964,P00846,P56385,P24539 4 +Proton transporting atp synthase activity rotational mechanism 0.6201288472070488 1.9244826315632737 0.0542941157336804 1.0 0.2955883192770253 11 O75964,P00846,P56385,P24539 4 +Wide pore channel activity 0.8035142850727967 1.923880044915363 0.0543696210633952 1.0 0.2955883192770253 5 P45880,Q9Y277,P21796 3 +Peptide binding 0.446755991399377 1.912024148318092 0.0558730967607257 1.0 0.300484914293758 82 Q9UHB9,Q15388,P24390,O00264,Q9H7Z7,P04439,Q9NZ08,Q15392,P52292,Q9Y584,P55899,Q03518,Q8WTV0,Q9NQX7,O14773,Q9UIQ6,O43731,P42892,Q92973,P40855,Q9Y287 21 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9935156470256552 1.8774856190009963 0.0604515665384903 1.0 0.3073273257769255 2 P09601 1 +Gated channel activity 0.5404767235203223 1.8769782732144904 0.0605210717392237 1.0 0.3073273257769255 15 P45880,Q9NW15,P51790,P21796,P51797,Q9Y277,Q9C0H2 7 +Hexosaminidase activity 0.792474270144337 1.875348131223356 0.0607448458584631 1.0 0.3073273257769255 5 P54802,P17900 2 +Atpase coupled cation transmembrane transporter activity 0.5224853503399733 1.87525839008428 0.0607571847573344 1.0 0.3073273257769255 17 Q9HD20,P16615,P36543,Q04656,P20020,P05026,P23634,P06576,P05023 9 +Mannose binding 0.7412412656691527 1.8727319048874311 0.0611054153122656 1.0 0.3077016465012665 6 O75503,P49257,P35613,Q12907 4 +Adp transmembrane transporter activity 0.8437235543018388 1.864045358401452 0.0623153348831546 1.0 0.3115766744157733 4 P05141,P12236,P12235 3 +Lysophospholipid acyltransferase activity 0.6790587251681812 1.8414668596603032 0.0655531727736713 1.0 0.3187551184699139 7 Q96N66,Q92604,Q8NF37,Q9NUQ2 4 +Lysophosphatidic acid binding 0.983930081759232 1.8379382027148732 0.0660715119412405 1.0 0.3192050950510067 2 P50897 1 +Manganese ion transmembrane transporter activity 0.8357606734308907 1.8305923536100168 0.0671614107047893 1.0 0.3232428440383567 4 Q9HD20,Q9HC07 2 +Calcium ion binding 0.4371136908758651 1.8247577434044704 0.0680375951873288 1.0 0.3263498209832893 93 Q96D71,O43707,P80303,Q9UJS0,Q9H223,P04083,Q02818,Q9BPX6,Q13813,P55327,Q8IYU8,P98164,Q96A33,Q8NF37,Q07954,Q14257,P22413,Q9H4M9,O95202,P12814,O75746,P16615,O43681,P41208,Q9Y680,O60476,Q9NWM8,Q9UM22,A0FGR8,O95302,P14314,Q6NUK1,O94923,Q13586,Q9BRK5,Q99584,P27824,Q96AY3,P14625,O75071,O43852 41 +Solute anion antiporter activity 0.7289939935617237 1.8152401165004663 0.0694870172008323 1.0 0.3277470977972594 6 P04920,P12235,P12236,P05141 4 +Er retention sequence binding 0.9760360868339416 1.805310404253048 0.0710261224532329 1.0 0.3316896477601471 2 P24390 1 +Syntaxin binding 0.4916485961116978 1.7984158330824225 0.0721111355558787 1.0 0.3356488710906858 20 Q8N1B4,O43752,P49755,Q8WVM8,O60499,O95721 6 +Tap binding 0.8248236953455649 1.7844991457241106 0.0743425934968571 1.0 0.3386097038755636 4 P10321,Q03518,P04439 3 +Procollagen proline dioxygenase activity 0.8242595204513469 1.7821169989733372 0.0747301542731833 1.0 0.3386097038755636 4 P13674,P07237,Q32P28 3 +Lipid transfer activity 0.5932025414935991 1.7670294073331585 0.0772233035086003 1.0 0.3446512150202994 11 P61916,P30536,Q9Y255,Q99758,Q14849 5 +Phospholipid transporter activity 0.6188508287663917 1.7656464337615074 0.0774551847183429 1.0 0.3446512150202994 9 Q9Y255,P08183,Q9NV96,Q99758 4 +Intramembrane lipid transporter activity 0.7634372563405725 1.7467139325672452 0.0806869723830931 1.0 0.3512986643756211 5 Q99758,Q9NV96,Q96AA3 3 +Atpase coupled intramembrane lipid transporter activity 0.7634372563405725 1.7467139325672452 0.0806869723830931 1.0 0.3512986643756211 5 Q99758,Q9NV96,Q96AA3 3 +Rna strand annealing activity 0.7623849528158715 1.7420264736885318 0.0815038119544602 1.0 0.3531001926675159 5 P51114,Q06787 2 +Modified amino acid transmembrane transporter activity 0.8146189289573906 1.7413451633774708 0.0816230941185822 1.0 0.3531001926675159 4 Q9H2D1 1 +Abc type xenobiotic transporter activity 0.8124118476727775 1.7319938280960634 0.0832746613398947 1.0 0.3531001926675159 4 P33527,P08183,Q99758 3 +Efflux transmembrane transporter activity 0.8124118476727734 1.7319938280960483 0.0832746613398973 1.0 0.3531001926675159 4 Q9NP58,P08183,P33527 3 +Palmitoyl protein hydrolase activity 0.756376302798056 1.715228136409879 0.0863034082017812 1.0 0.3618790884503013 5 P50897 1 +Transmembrane transporter binding 0.4218070663511197 1.701669465861478 0.0888173474071243 1.0 0.3696369017090615 31 P16615,Q96PU5,P30536,Q9HD47,Q06787,Q96RD7,P21796,P62942 8 +Aminoacyltransferase activity 0.9500986749365612 1.697769326996993 0.0895513072147302 1.0 0.3705119874527582 2 Q9NXS2 1 +Palmitoyltransferase activity 0.7518563337455528 1.6950329128019503 0.0900691773505522 1.0 0.3715681806152517 5 O15498,P23786,O15269 3 +P type calcium transporter activity 0.8030712822084141 1.6923496336151302 0.0905793295166814 1.0 0.3725864862386752 4 P20020,P23634 2 +Organic cation transmembrane transporter activity 0.750699799068896 1.6898605925921937 0.0910546283170132 1.0 0.3734559393291993 5 Q9HC21,Q70HW3 2 +Phospholipase d activity 0.946433605864105 1.6825368047019975 0.0924647942870144 1.0 0.3768780267731405 2 P09601 1 +Ribosomal protein s6 kinase activity 0.9461516774739218 1.6813647420539932 0.0926920895687217 1.0 0.3768780267731405 2 Q15418 1 +Protein lipid complex binding 0.7487559405036643 1.681162695313318 0.0927313172975461 1.0 0.3768780267731405 5 Q8WTV0,Q9BQE5 2 +Sodium channel inhibitor activity 0.9433323935720276 1.6696416058382677 0.0949902934509794 1.0 0.3806216167113223 2 P46934 1 +Sulfotransferase activity 0.9430504651818424 1.6684690455289937 0.0952226518132919 1.0 0.3806216167113223 2 Q7LGA3 1 +Oxidoreductase activity acting on nad p h 0.4196681628338238 1.6582973392234264 0.0972574658171052 1.0 0.3833239251264437 30 O95139,P03886,Q13423,Q9P0J0,Q7KZN9,O43676,O96000 7 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.7947413701253656 1.6569047654194633 0.0975387307749882 1.0 0.3833239251264437 4 Q7KZN9 1 +Amyloid beta binding 0.5157449038781301 1.6561173302008594 0.0976980604322343 1.0 0.3833239251264437 14 Q9NQX7,O00264,Q8WTV0 3 +Galactosyltransferase activity 0.6950311005550278 1.6543032707841885 0.0980659087602633 1.0 0.3833239251264437 6 Q16880,O43505 2 +C4 dicarboxylate transmembrane transporter activity 0.6922516499526129 1.6410404770612832 0.1007890131902449 1.0 0.3898036481331365 6 Q9UBX3,Q9UJS0,Q9H936,O75746 4 +Glucosidase activity 0.7340912876786838 1.6153703229307437 0.1062305230171425 1.0 0.399777101248023 5 P10253 1 +Pattern recognition receptor activity 0.9255709049901346 1.595692401578492 0.1105574859213072 1.0 0.4130478231368282 2 Q8WTV0 1 +Solute proton symporter activity 0.7790067123410469 1.5897354392525362 0.1118944518008842 1.0 0.4130478231368282 4 Q96ES6 1 +Volume sensitive anion channel activity 0.776143837592725 1.5774857292282822 0.1146838032089374 1.0 0.4164142174242016 4 Q9C0H2 1 +Galactoside binding 0.9210600507471112 1.5768899794759417 0.1148208426267445 1.0 0.4164142174242016 2 P16278 1 +Solute sodium symporter activity 0.7757404795486823 1.57575916790264 0.1150813158343546 1.0 0.4164142174242016 4 Q96QD8,Q9H2J7,Q9Y6M7 3 +Atpase coupled inorganic anion transmembrane transporter activity 0.7754583921015747 1.5745516046847985 0.1153599810814749 1.0 0.4164142174242016 4 P33527,O15439,P51797 3 +Vitamin d binding 0.9193684804059788 1.569837231632735 0.1164529833716527 1.0 0.4172071567957383 2 P04062 1 +Pdz domain binding 0.5201031317100089 1.5661490795828483 0.117313720388124 1.0 0.4183813345805444 13 Q15058,Q15067,P51790,P20020,Q96A65,P23634,Q8IUD2 7 +L ascorbic acid binding 0.6249978473881809 1.563066292613165 0.1180370029338742 1.0 0.4196257897228528 7 P13674,Q32P28 2 +Mannosyltransferase activity 0.7220366558526516 1.5610701542989365 0.1185071991408537 1.0 0.4196257897228528 5 Q6ZXV5 1 +Mhc class ib protein binding 0.9140118409923792 1.5474976928372066 0.1217432803809055 1.0 0.4243023195541412 2 Q9NUQ9 1 +Channel inhibitor activity 0.6715298154881629 1.5417646590197938 0.1231307930023233 1.0 0.4277843847209087 6 Q96PU5,P46934,P62942 3 +Glycosaminoglycan binding 0.4638126973571651 1.5282824494704843 0.1264424254970308 1.0 0.4308362772311582 19 O14737,Q53GQ0,Q07021,P05067,Q06481,P15586 6 +Carbohydrate binding 0.3980718611772673 1.5275526819033856 0.1266236376961516 1.0 0.4308362772311582 50 Q12907,P52789,Q5KU26,Q32P28,Q16706,P22413,P13674,O75503,Q8N4A0,P10253,O00754,P49257,P08236,O14735,Q13438,Q10472,Q9NPA0,P27824,O15460,P35613 20 +Signal recognition particle binding 0.6681514721633262 1.5255170969554686 0.1271301724783404 1.0 0.4308362772311582 6 Q9UHB9,Q9GZP9,Q9BUN8 3 +Calcium channel regulator activity 0.6675884965541894 1.5228079732024569 0.1278067546177972 1.0 0.4308362772311582 6 Q13586,Q9NWR8,P62942 3 +Nuclear import signal receptor activity 0.495700637219101 1.519560064559066 0.1286215812660693 1.0 0.4311074099683473 14 Q53FT3,P52292 2 +Intracellular calcium activated chloride channel activity 0.9066817028474672 1.5169159142884254 0.1292879150787476 1.0 0.4311074099683473 2 Q9C0H2 1 +Ion gated channel activity 0.9066817028474672 1.5169159142884254 0.1292879150787476 1.0 0.4311074099683473 2 Q9C0H2 1 +Phospholipid transfer activity 0.7115069742109772 1.5134929030433313 0.1301545025082453 1.0 0.4311074099683473 5 Q9Y255 1 +Proteoglycan binding 0.7607862703779313 1.5116386018329269 0.1306258258939294 1.0 0.4311074099683473 4 P10586,O00560 2 +Mhc class i protein binding 0.5825494271661905 1.5103980404796502 0.1309418883394966 1.0 0.4311074099683473 8 Q03518,P06576,Q9BUN8 3 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.9153976311336725 1.5103829882698885 0.130945726885703 1.0 0.4311074099683473 3 Q16850,Q15800 2 +Gtp dependent protein binding 0.5689380860893628 1.4973262843941628 0.1343083788364711 1.0 0.4347413918062525 10 Q9BZG1,P53365,O00429,Q13637,Q86YV9 5 +Snare binding 0.3934814777876638 1.4966365152282493 0.1344878633656385 1.0 0.4347413918062525 34 O95295,Q8N1B4,Q12846,O43752,O14653,Q8WVM8,P49755,O60499,O15400,O95721,Q86Y82,Q13190 12 +L ornithine transmembrane transporter activity 0.8985057795320024 1.4827944443175591 0.1381290325952067 1.0 0.4432031317964115 2 Q9Y619 1 +Ganglioside binding 0.9032712915961671 1.4629282152427077 0.1434870224943591 1.0 0.4506918665279078 3 Q9NZJ7,P07602 2 +Glycosphingolipid binding 0.9032712915961671 1.4629282152427077 0.1434870224943591 1.0 0.4506918665279078 3 Q9NZJ7,P07602 2 +Beta n acetylhexosaminidase activity 0.7467262976858381 1.45117876831084 0.1467300873889183 1.0 0.4562984894507024 4 P17900 1 +Misfolded protein binding 0.485563759528806 1.4500397729741257 0.1470474284024878 1.0 0.4562984894507024 14 P48723,Q9GZP9,Q9BUN8,P46379,Q6NTF9,Q13217 6 +Heparin binding 0.5011052520754038 1.441471340617056 0.1494515683059365 1.0 0.4603402683299555 13 P05067,Q06481,O14737,Q53GQ0 4 +Beta 2 microglobulin binding 0.8866647871440541 1.433370112457165 0.1517520949334541 1.0 0.4603402683299555 2 P55899 1 +Flippase activity 0.7414340388810574 1.4283844682552105 0.153181227188254 1.0 0.4603402683299555 4 Q99758,Q9NV96 2 +Cytoskeleton nuclear membrane anchor activity 0.7412844012355826 1.4277397036952069 0.1533667936740017 1.0 0.4603402683299555 4 Q8WXH0,Q9UH99 2 +Sterol transfer activity 0.692496704632068 1.4272962638057682 0.1534945170901527 1.0 0.4603402683299555 5 P30536,Q14849 2 +Molecular function inhibitor activity 0.5341045897705159 1.4143818160123829 0.1572498262213697 1.0 0.463425823140532 11 Q9NWR8,Q96PU5,P46934,P62942 4 +Protein homodimerization activity 0.2708706610214727 1.406606976320936 0.1595439632677113 1.0 0.463425823140532 191 Q8TCT9,P51116,P33897,Q8NAN2,O43707,P09601,Q03164,O00264,Q04837,Q8N2A8,O75150,Q9NZJ7,O15217,Q15070,O75027,Q8IY95,Q9BRG1,Q14849,Q16706,Q9HB71,P06280,P16278,P55327,Q9HD42,P07900,P51648,Q8TBA6,Q03518,P12270,P22413,P27105,Q06787,O95684,P07602,Q9UKU0,P22830,P02786,P51114,Q9Y371,Q99623,O75208,P23246,O75569,Q8TCT8,Q07820,Q9UII2,P42892,O00429,Q15067,Q99584,P09493,Q14108,Q06481,O94923,O95772 55 +Mitochondrial ribosome binding 0.7353363122688419 1.4020996847283684 0.1608854812174729 1.0 0.463425823140532 4 Q15070 1 +Lipase activity 0.4186258771732364 1.4019088113133922 0.1609424789309506 1.0 0.463425823140532 23 Q9H6V9,Q8NCC3,P09601,Q8NHP8,Q9NZC3,Q8NCG7,Q9NP80,Q8IV08 8 +Iron ion transmembrane transporter activity 0.8790527206089562 1.401602149634937 0.1610340847276985 1.0 0.463425823140532 2 Q8N4V1 1 +Mannosidase activity 0.7350097934714636 1.4006916104801252 0.1613063125486529 1.0 0.463425823140532 4 O00754,O60476 2 +Proline rich region binding 0.593827480834051 1.3999827750228204 0.1615184766340935 1.0 0.463425823140532 7 P46934 1 +Sphingosine n acyltransferase activity 0.8866328257191219 1.3977614272243013 0.1621847211029399 1.0 0.463425823140532 3 P27544,Q96G23 2 +Ubiquinone binding 0.8779250070481979 1.3968965901090182 0.1624446701609214 1.0 0.463425823140532 2 Q16134 1 +G protein alpha subunit binding 0.7331477024093527 1.3926604992054628 0.163722478847422 1.0 0.4642631414210466 4 P80303,Q02818 2 +Oxidative phosphorylation uncoupler activity 0.874823794756131 1.383957762025361 0.166371388351679 1.0 0.4689552082024421 2 P12235 1 +Nucleobase transmembrane transporter activity 0.874823794756131 1.383957762025361 0.166371388351679 1.0 0.4689552082024421 2 P12235 1 +Zinc ion transmembrane transporter activity 0.8793006204173657 1.3690354181049131 0.1709882039324877 1.0 0.4765947004227912 3 Q8TAD4,Q8N1S5 2 +Azole transmembrane transporter activity 0.8711587256836785 1.3686696875609636 0.1711025496924225 1.0 0.4765947004227912 2 P30825 1 +Phosphoric diester hydrolase activity 0.4884589189737215 1.358010615667455 0.1744603157143582 1.0 0.4821510678433925 13 P09601,Q9NZC3,Q8N2A8,Q8IV08 4 +Phospholipase a1 activity 0.8672117282210303 1.352210418385337 0.1763080117820046 1.0 0.4858018097834422 2 Q8NCC3 1 +Phosphatidylcholine transporter activity 0.7231608968467964 1.349560590356435 0.1771569726453141 1.0 0.4867516821225622 4 Q99758 1 +Mitochondrion targeting sequence binding 0.8709014530160215 1.3361314457884528 0.1815063133946592 1.0 0.492916821681149 3 Q9Y584 1 +Calcium channel inhibitor activity 0.8627008739779962 1.333407196333252 0.182398212092516 1.0 0.492916821681149 2 P62942 1 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.7193229901269435 1.3329872680711965 0.182535982021853 1.0 0.492916821681149 4 O95864,O60427,O75845 3 +Solute proton antiporter activity 0.8607273752466915 1.3251836337549674 0.1851102522499812 1.0 0.4953600299149023 2 O95202 1 +Electron transfer activity 0.3837048242175174 1.3221971142827944 0.1861025217620766 1.0 0.495496016106594 55 O95139,Q9UDW1,P16435,O14548,P03886,P00403,Q9P0J0,P13073,Q7KZN9,Q16134,O43676,P14406,O96000 13 +Lipid kinase activity 0.8593177332957441 1.319310829660725 0.1870652187756258 1.0 0.495496016106594 2 Q53H12 1 +Translation repressor activity 0.5384763587230466 1.3115993543861146 0.1896553509901442 1.0 0.4978908796713119 9 P00374,Q14011 2 +Cis trans isomerase activity 0.3826785605510496 1.300622937044846 0.1933875519226517 1.0 0.5003071916754919 30 Q9Y680,P26885,Q96AY3,Q9NWM8,O95302,P62942 6 +Lipoprotein particle receptor activity 0.7072680398189171 1.2809069713507597 0.200226343872194 1.0 0.5151277755984629 4 P98164,Q8WTV0 2 +Neutral amino acid transmembrane transporter activity 0.6599887133182741 1.2792451881196771 0.2008107276239767 1.0 0.5156936108673814 5 Q96NB2,Q96QD8,P08195,Q9H9B4 4 +Sequence specific mrna binding 0.5688169168887404 1.268199287816473 0.2047267913094403 1.0 0.5216228460217925 7 P00374 1 +Lysophospholipase activity 0.613173750810332 1.2592598504401389 0.2079364900331499 1.0 0.5234790352484754 6 Q9NZC3,Q8NCC3 2 +Beta galactosidase activity 0.8446574570059082 1.2583041951851133 0.2082817645546937 1.0 0.5234790352484754 2 P16278 1 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.6545445894587205 1.2544035847510835 0.2096953502576686 1.0 0.5242383756441715 5 Q15418 1 +Galactosidase activity 0.8448956570783925 1.2343511915613985 0.2170720680922619 1.0 0.5379281547295108 3 P06280,P16278 2 +Ferrous iron binding 0.6913884331047597 1.212291905091089 0.2254006614474537 1.0 0.5489534181551584 4 P22830 1 +Carnitine o acyltransferase activity 0.8328164646179725 1.2091514554343217 0.2266046638444174 1.0 0.5490506838011142 2 P23786 1 +O palmitoyltransferase activity 0.8328164646179725 1.2091514554343217 0.2266046638444174 1.0 0.5490506838011142 2 P23786 1 +Cardiolipin binding 0.8314068226670341 1.203308949780273 0.2288567870063715 1.0 0.5516735155264323 2 O60313 1 +Cullin family protein binding 0.5560302960610206 1.2006412721953927 0.2298903840264776 1.0 0.5522833504201458 7 O60826,Q4G0X4,Q9BTE7,Q92564 4 +2 acylglycerol 3 phosphate o acyltransferase activity 0.8353073886068749 1.1968996621936268 0.2313456658664843 1.0 0.5538986754671325 3 Q96N66,Q8NF37 2 +Nadplus kinase activity 0.8329895972872854 1.1878552869597814 0.2348904281726658 1.0 0.5576677111817485 3 Q53H12 1 +Glutamate receptor binding 0.5245225697279656 1.1864953518358878 0.2354267360177155 1.0 0.5580047428225586 8 P23634,P27824 2 +Low density lipoprotein particle binding 0.8257436943756064 1.1596068160819997 0.2462089246023588 1.0 0.5698617359423064 3 Q8WTV0 1 +Procollagen proline 4 dioxygenase activity 0.8240270727580311 1.1529208272262943 0.2489428826226558 1.0 0.5709143904555235 3 P13674,P07237 2 +Peptidyl proline 4 dioxygenase activity 0.8240270727580311 1.1529208272262943 0.2489428826226558 1.0 0.5709143904555235 3 P13674,P07237 2 +Oxidoreductase activity acting on the ch nh group of donors 0.5071601816905966 1.1401229377416753 0.2542350869360552 1.0 0.5789029110910522 10 P00374 1 +Oligosaccharyl transferase activity 0.6744729948895336 1.13927046301046 0.2545903639975158 1.0 0.5789029110910522 4 P04844,P46977 2 +Magnesium ion transmembrane transporter activity 0.8172758338833026 1.126652128486862 0.259889589918159 1.0 0.5835612584553818 3 Q8N4V1 1 +Tripeptide transmembrane transporter activity 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.5835612584553818 2 P33527 1 +Atpase coupled lipid transmembrane transporter activity 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.5835612584553818 2 P33527 1 +Oligopeptide transmembrane transporter activity 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.5835612584553818 2 P33527 1 +Abc type glutathione s conjugate transporter activity 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.5835612584553818 2 P33527 1 +Glutathione transmembrane transporter activity 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.5835612584553818 2 P33527 1 +Heme transmembrane transporter activity 0.81528482797518 1.118913862066037 0.2631768885938506 1.0 0.585927293444506 3 O75027,O15173 2 +Nucleocytoplasmic carrier activity 0.3929593249838119 1.1167449783913317 0.2641033804617398 1.0 0.5866660649189355 22 P55060,O60518,Q8TEX9,O15504,Q92973,Q9C0E2,Q96P70,Q9Y5L0,Q53FT3,P52292 10 +Glucosyltransferase activity 0.4847224821058105 1.1150204104480743 0.2648416754178677 1.0 0.5873839666399417 11 P04062 1 +Peptide transmembrane transporter activity 0.8121827411167443 1.106865714073241 0.2683519913973149 1.0 0.5879723619435754 3 P33527,Q03518 2 +Insulin like growth factor i binding 0.8080067662813677 1.106682559351504 0.2684311984562189 1.0 0.5879723619435754 2 P06756 1 +Acetylgalactosaminyltransferase activity 0.8093311798641973 1.0958001318031882 0.2731662508095243 1.0 0.5910418626495865 3 Q8N4A0 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.8093311798641973 1.0958001318031882 0.2731662508095243 1.0 0.5910418626495865 3 Q8N4A0 1 +Gpi anchor binding 0.8090806542583204 1.0948284126512275 0.2735918162794906 1.0 0.5910418626495865 3 O43292,Q9H490 2 +Long chain fatty acid transporter activity 0.6192095623888676 1.093216178358634 0.2742988953735699 1.0 0.5912448673530846 5 P33897 1 +Atp dependent peptidase activity 0.618792325056408 1.09131599136583 0.2751338635849354 1.0 0.5912448673530846 5 Q16740,Q96TA2,Q9Y4W6,P36776 4 +Organic acid sodium symporter activity 0.8037778404285134 1.0893058716367392 0.2760190243477889 1.0 0.5912448673530846 2 Q9H2J7 1 +Amino acid sodium symporter activity 0.8037778404285134 1.0893058716367392 0.2760190243477889 1.0 0.5912448673530846 2 Q9H2J7 1 +Voltage gated channel activity 0.4614026465219678 1.0862302815664997 0.2773771231755071 1.0 0.5913528506151637 12 P45880,P51790,P21796,P51797,Q9Y277 5 +Acidic amino acid transmembrane transporter activity 0.6612630951651175 1.082365325735101 0.2790902292614645 1.0 0.5913528506151637 4 Q9UJS0,O75746 2 +L aspartate transmembrane transporter activity 0.6612630951651175 1.082365325735101 0.2790902292614645 1.0 0.5913528506151637 4 Q9UJS0,O75746 2 +Serine transmembrane transporter activity 0.6598025387870273 1.0760829426851763 0.2818901634907484 1.0 0.5939672519890308 4 Q96QD8,Q9H9B4,Q96NB2 3 +Potassium ion transmembrane transporter activity 0.6593924314565027 1.0743193098932688 0.2826795933467436 1.0 0.5939672519890308 4 P05023,P55011 2 +Sulfuric ester hydrolase activity 0.7987031294051213 1.0684951604769055 0.2852972122538069 1.0 0.5939672519890308 2 P15586 1 +Transmembrane receptor protein kinase activity 0.7972934874541855 1.0627228507154982 0.2879076550607764 1.0 0.5939672519890308 2 Q15375 1 +Transmembrane receptor protein tyrosine kinase activity 0.7972934874541855 1.0627228507154982 0.2879076550607764 1.0 0.5939672519890308 2 Q15375 1 +Amide binding 0.3630319058228151 1.062376162121376 0.2880649511385318 1.0 0.5939672519890308 119 Q9UHB9,Q15388,P24390,O00264,Q9NZJ7,Q9H7Z7,Q02790,P04439,Q9NZ08,P00374,Q15392,P52292,Q9Y584,P55899,Q03518,Q8WTV0,Q9NQX7,O14773,P07602,Q9UIQ6,P62942,Q9Y680,P26885,O43731,P21796,Q9UM22,P42892,P45880,Q92973,P40855,Q96AY3,Q9Y287 32 +Protein phosphatase regulator activity 0.3990233845734565 1.0607582087221297 0.2887997990189435 1.0 0.5939672519890308 20 P30153,Q01105,Q86XL3,P30154,Q6IN85 5 +Thiolester hydrolase activity 0.4180993595334487 1.0602668403302833 0.2890232203524274 1.0 0.5939672519890308 16 P50897,Q9UMR5 2 +Histone methyltransferase activity h3 k36 specific 0.6509434566317778 1.0380267314528977 0.2992576101521018 1.0 0.6075315901940087 4 Q9BZ95 1 +Structural constituent of synapse 0.5245143380876514 1.0341302969916644 0.3010752543107147 1.0 0.6094727966375698 7 P07196,O15020,P12814,Q16352 4 +Modified amino acid binding 0.360820970258061 1.0270270197419185 0.3044077412516808 1.0 0.6135854043748267 25 P49327,Q9H7Z7,Q8WTV0,Q14108,Q06481,P00374,Q08431 7 +Copper ion binding 0.4868403102423682 1.0223274386399923 0.3066259507957909 1.0 0.6144042985397346 10 O75880,Q04656,Q9Y6N1,P00403,Q99584 5 +Protein disulfide isomerase activity 0.4857045944460474 1.015755729068908 0.3097457225675226 1.0 0.614752794117938 10 P07237,Q92643,Q96JJ7,Q9BS26,Q6ZRP7 5 +Nadh dehydrogenase activity 0.3740282341643585 1.0135415531128105 0.3108015587324275 1.0 0.614752794117938 23 O95139,Q9P0J0,P03886,O43676 4 +Phosphatidyl phospholipase b activity 0.7880351433872327 1.0135003425638025 0.3108212325866808 1.0 0.614752794117938 3 Q8NCC3 1 +Sulfatide binding 0.7875148904857435 1.011498371039861 0.3117779603802511 1.0 0.614752794117938 3 P50897 1 +Aspartic type peptidase activity 0.5621317570116398 1.0110318012175683 0.3120012093917768 1.0 0.614752794117938 6 Q92542,Q8TCT8 2 +Aspartic endopeptidase activity intramembrane cleaving 0.783981951494632 0.9979156359789552 0.3183202692663869 1.0 0.6210865259046829 3 Q92542,Q8TCT8 2 +Nitric oxide synthase binding 0.7812235692134222 0.9972081712987648 0.3186634754818374 1.0 0.6210865259046829 2 P23634 1 +Nadph binding 0.5585987374705071 0.9939150205164782 0.3202642410402243 1.0 0.6233478694249208 6 P00374,Q14739 2 +Catalytic activity acting on a glycoprotein 0.7799519085146505 0.982448899687701 0.325878745873724 1.0 0.6265765265705405 3 O43505 1 +Exopeptidase activity 0.3432486100717636 0.9820453543198931 0.3260775048378344 1.0 0.6265765265705405 34 Q9UIQ6,P02786,O75844,P42785,O14773,Q92820,Q9HB40,Q9NZ08,Q9H3G5,Q9NXS2,Q7Z2K6,O75976,P10619 13 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7789058093626623 0.9784390470650732 0.3278572239822981 1.0 0.6265765265705405 3 P04844,P46977 2 +High density lipoprotein particle binding 0.7782003817579053 0.9757362166108768 0.3291952000216014 1.0 0.6265765265705405 3 Q9BQE5 1 +Acetylglucosaminyltransferase activity 0.5129205730977647 0.9730726436658892 0.3305171991334059 1.0 0.6265765265705405 7 Q93063,O43505,P07686,P06865,P26572 5 +Chloride transmembrane transporter activity 0.7750211446292488 0.9720806434150828 0.3310104309804471 1.0 0.6265765265705405 2 P51797 1 +Phosphatidylglycerol binding 0.7770402470321471 0.971293276565115 0.3314022559166831 1.0 0.6265765265705405 3 O60313 1 +Voltage gated chloride channel activity 0.7752397067117844 0.9644030270768122 0.3348439051826675 1.0 0.6291224455851763 3 P51797,P51790 2 +Adrenergic receptor binding 0.63354974283588 0.9636218170215722 0.3352355646439737 1.0 0.6291224455851763 4 P46934 1 +Annealing activity 0.4761259396505453 0.9604150342873776 0.336846374487328 1.0 0.6304503203134614 10 P51114,Q06787 2 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.7719199323371928 0.9595538948762063 0.3372797826694631 1.0 0.6304503203134614 2 Q53GQ0 1 +Monocarboxylic acid transmembrane transporter activity 0.588012361045439 0.9516652189057984 0.3412667940360967 1.0 0.6309254798403894 5 O15439,P53985 2 +Mhc protein complex binding 0.4823658150048497 0.9505452612337152 0.3418352672667026 1.0 0.6309254798403894 8 P07900,Q9NUQ9,P62258 3 +Collagen binding 0.4819877813939368 0.9484397008928774 0.3429056564127517 1.0 0.6309254798403894 8 Q92791,Q32P28 2 +P type potassium transmembrane transporter activity 0.7691006484352995 0.9481884682023078 0.3430335167316376 1.0 0.6309254798403894 2 P05023 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.5463585665366886 0.9347634997631538 0.3499101939260547 1.0 0.6344258788432389 6 Q9UHG3,Q8NBM8 2 +Nedd8 specific protease activity 0.7673434856176007 0.934264994677922 0.3501672165205438 1.0 0.6344258788432389 3 Q92905,Q9BT78 2 +Structural constituent of nuclear pore 0.3873213886571457 0.9307264992611805 0.351995058515941 1.0 0.6352972038266028 19 Q12769,Q8NFH5,Q7Z3B4,P57740,Q8N1F7,Q9BTX1,Q92621,P12270,Q99567,P35658 10 +Phospholipase activity 0.3837254064234547 0.9027256556888548 0.3666715166023682 1.0 0.6525291321771749 19 Q8NCC3,P09601,Q8NHP8,Q9NZC3,Q9NP80,Q8IV08 6 +O acetyltransferase activity 0.7564138708767832 0.8973305080388305 0.369542581797901 1.0 0.6525291321771749 2 Q8NF37 1 +Glycosyltransferase activity 0.3401886796154348 0.8813433363338641 0.3781320169066222 1.0 0.6626780423062274 51 Q9H3H5,Q2TAA5,Q10471,Q16880,O60762,P04843,P46977,Q8NBJ5,P04062,Q13126,Q9NYU2,Q16739,P43490,P06865,Q6ZXV5,Q8N4A0,P15291,Q9BT22,O43505,P26572,Q10472,P04844,P07686 23 +Inorganic anion exchanger activity 0.7507753030730009 0.8748904490938127 0.3816335163051145 1.0 0.665038701443026 2 Q9Y6M7 1 +Threonine type peptidase activity 0.4605896790269772 0.8711052538849502 0.383696685698399 1.0 0.6662215682561742 10 Q9UJ14,P28072 2 +Fibronectin binding 0.7502446431474123 0.869497753468182 0.3845749363059876 1.0 0.6662215682561742 3 Q53GQ0 1 +Beta tubulin binding 0.37944185602167 0.8694462620655652 0.3846030887089982 1.0 0.6662215682561742 19 Q9UBK9,O14737,P50402 3 +Structural constituent of postsynapse 0.6104772634873086 0.8658277483829239 0.3865846298236488 1.0 0.6665906643615838 4 P07196,Q16352 2 +Ubiquitin conjugating enzyme binding 0.4602685113862255 0.8644972130757839 0.3873148106396213 1.0 0.6667280499453335 9 Q9UBS8,Q9BTE7,Q92564 3 +Coa hydrolase activity 0.4596183655812419 0.8608210401798395 0.3893366149911352 1.0 0.6677712851060077 9 P50897 1 +Acid phosphatase activity 0.5669517283127669 0.857069748603955 0.3914063386479758 1.0 0.6691597549493261 5 Q9NPH0 1 +Amino acid cation symporter activity 0.7447828539199014 0.8489709703070473 0.3958974458263224 1.0 0.6716965058084488 3 Q96QD8,Q9H2J7 2 +Lipase binding 0.7414716661967908 0.838108296036334 0.4019698840374037 1.0 0.6758183767478748 2 Q96CS3 1 +Solute cation antiporter activity 0.7415713634472931 0.8369416540490754 0.4026253650872498 1.0 0.6758183767478748 3 O95202 1 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.5250876604677664 0.8327378397860381 0.4049925986345535 1.0 0.6773812376689046 6 Q15418 1 +Insulin like growth factor binding 0.6012587453556845 0.8271369443356131 0.4081594463767011 1.0 0.6794654313212142 4 P98164,P06756 2 +Microtubule minus end binding 0.4845565521377812 0.8248614915548181 0.4094502310171979 1.0 0.6805456767060544 7 Q9BSJ2,Q9UGJ1 2 +Rna polymerase ii general transcription initiation factor activity 0.48077438217142 0.8052811758726048 0.4206574419615618 1.0 0.6912431392768627 7 P29083,Q9Y6J9 2 +Metallopeptidase activity 0.3241367097598485 0.7891887176655695 0.4300017151542583 1.0 0.698567654355081 44 Q9UIQ6,P02786,Q7Z2K6,Q9HD42,O75844,Q10713,O15372,P55786,Q92905,Q9BYT8,Q5JRX3,Q9NZ08,Q969V3,Q96TA2,Q9NXS2,P42892,Q96E52,O75976 18 +Ubiquitin specific protease binding 0.4450369079360945 0.7825347743674053 0.4339003570320965 1.0 0.7030276638066317 10 Q9GZP9,Q9BUN8,P46379,Q9Y3E7,Q86TM6 5 +Cytokine receptor binding 0.3326806300122129 0.7684990462711891 0.4421907570599308 1.0 0.7126422793164033 25 Q9H2J4,P62942 2 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.7211728221031922 0.7590530162564856 0.4478208431556534 1.0 0.7169345283994113 2 O95881 1 +Threonine type endopeptidase activity 0.4475059122335207 0.7582256344683315 0.4483159175610014 1.0 0.7169345283994113 8 P28072 1 +Fibroblast growth factor binding 0.5088417475285614 0.7557513809264507 0.449798271745695 1.0 0.7169522690773071 6 Q92896,Q99584 2 +Phospholipase binding 0.5828695112939292 0.7507960576651527 0.4527754023784658 1.0 0.7169522690773071 4 P07196 1 +Apolipoprotein binding 0.582177282586382 0.7479472035924121 0.4544920037896427 1.0 0.7169522690773071 4 Q8WTV0,P27824 2 +Phosphatase regulator activity 0.3487901740792806 0.7448558477880549 0.4563588689112006 1.0 0.7190955451106333 22 P30153,Q01105,Q86XL3,P30154,Q6IN85 5 +Pyruvate dehydrogenase acetyl transferring kinase activity 0.7154540327129106 0.740372995039935 0.4590737001706859 1.0 0.7207573538131047 3 O14874,Q15118 2 +Phospholipid binding 0.3460528932164322 0.7250041607973047 0.4684494778537051 1.0 0.7260197274512517 101 Q9H4A6,Q13045,Q9NZJ7,Q01082,P50897,Q9H490,Q08431,Q9BWH2,Q92643,O15020,O43292,Q8WTV0,O14773,P07602,Q8NFH5,P53365,O60313,Q9UJZ1,P21796,Q9UM22,A0FGR8,P45880,Q8NCC3,O00560,Q96L92,Q9Y3E7,Q14108,O14964,Q86YQ8,Q06481 30 +Dioxygenase activity 0.3457249974806498 0.719500438829061 0.4718326319406507 1.0 0.7296646712524817 22 P07237,P16435,Q32P28,O15460,P13674 5 +Translation initiation factor binding 0.3643781438789909 0.7096410279412521 0.4779267705029753 1.0 0.7334776358586876 17 O75312,Q06787,P55010 3 +Organic hydroxy compound transmembrane transporter activity 0.7058657642413853 0.7055641484079459 0.4804592262062874 1.0 0.7349727622506992 3 O15439,P53985 2 +Scaffold protein binding 0.3320665282501897 0.7044041433654074 0.4811811264244021 1.0 0.735113822282819 24 P46108,P12956,Q9NZJ7,Q96RD7,P23634,P07602,P08670,Q16543,P62258 9 +Floppase activity 0.704900000240505 0.7020796397441592 0.4826294988697801 1.0 0.735113822282819 3 Q96AA3 1 +Mannosyl oligosaccharide mannosidase activity 0.7034393381207588 0.6968173058019536 0.4859171343867929 1.0 0.7369482799113741 3 O60476 1 +Thiol oxidase activity 0.7030456852791891 0.695400708126796 0.4868042168987809 1.0 0.7375031765650697 3 Q6ZRP7,P07237 2 +O methyltransferase activity 0.4325193655174694 0.6772413366800812 0.4982528445501915 1.0 0.7497523127374853 8 O60725 1 +Structural constituent of muscle 0.4896360608415127 0.6662037507424169 0.5052808758620153 1.0 0.7550358428396777 6 P09493,P67936 2 +Transcription elongation regulator activity 0.6966450521567487 0.6661523273606951 0.5053137407556005 1.0 0.7550358428396777 2 Q15061 1 +Glycerophospholipid flippase activity 0.6934224787913026 0.66099190675354 0.5086175038098517 1.0 0.755187584355656 3 Q99758 1 +General transcription initiation factor activity 0.4245866632502502 0.6349686773234385 0.5254488438543445 1.0 0.7732682045910243 8 P29083,Q9Y6J9 2 +Gamma tubulin binding 0.4244130303700812 0.634048646397874 0.5260490752795466 1.0 0.7732682045910243 8 Q9BSJ2,Q14155,Q9UGJ1 3 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3233108230830992 0.6284518435736196 0.5297079839915242 1.0 0.7732682045910243 24 O95139,Q9P0J0,P03886,O43676 4 +Oxidoreductase activity 0.2500022473230264 0.6228732826294918 0.5333677963746064 1.0 0.7756582033608099 241 O43169,Q9UDW1,Q06136,P09601,Q32P28,Q7LG56,Q9H7Z7,Q6YN16,Q96LJ7,O43676,P30519,P00374,Q15392,Q6UW02,O95139,P07237,P51648,O14548,P00403,Q14534,P21912,Q16134,Q6UX07,P13674,Q96CU9,Q16836,O75845,Q8N4Q0,P03886,Q3SXM5,Q13423,P04035,P13073,Q9UHG3,P14406,Q15800,O96000,Q16850,Q8NBM8,P16435,Q53GQ0,Q8N0U8,Q96JJ7,Q9BY49,Q9P0J0,Q14739,Q7KZN9 47 +Cytochrome b5 reductase activity acting on nad p h 0.6805510571730112 0.6156805936363423 0.5381053479069717 1.0 0.7783615126779494 3 P16435 1 +Hormone binding 0.4196366762901702 0.6088346086472071 0.5426340713039308 1.0 0.7825256501659492 8 P30536,P42892,P05023 3 +G quadruplex rna binding 0.6808570623061582 0.6081812467890155 0.5430672709985598 1.0 0.7825256501659492 2 Q06787 1 +Atpase activator activity 0.3728660896680612 0.6009381502413145 0.5478811820433371 1.0 0.7854628901634468 13 P54709,Q96DA6,O60884,Q96KC8,P05026,Q5JTV8,Q8IXB1 7 +Dynein light intermediate chain binding 0.4389570080591423 0.5935617645105463 0.552805260853019 1.0 0.7909195592588694 7 Q96ED9 1 +2 iron 2 sulfur cluster binding 0.3818263514663757 0.5901774007117302 0.5550717216112 1.0 0.7925595217758304 12 Q9NZ45 1 +Dna directed dna polymerase activity 0.4155145616933003 0.5872281388288096 0.5570504964102807 1.0 0.7932115979593632 8 Q9NR33,P56282 2 +Phosphatidylinositol 4 phosphate binding 0.4153490012180389 0.5863634588768862 0.5576312946384556 1.0 0.7932115979593632 8 Q9H4A6,Q9BZF1,P53365 3 +Nitric oxide synthase regulator activity 0.672024816694865 0.5861559809715774 0.5577706996251353 1.0 0.7932115979593632 3 P23634,P07900 2 +Molecular function activator activity 0.3547633486310075 0.5805307142521091 0.561556780487044 1.0 0.7960549562412549 15 P54709,Q9BZ95,Q96DA6,O60884,Q96KC8,P05026,Q5JTV8,Q8IXB1 8 +Carboxypeptidase activity 0.3782478758178604 0.5689113879149018 0.5694162767218058 1.0 0.8009948719514547 12 Q9HB40,P10619 2 +Toxic substance binding 0.6684522131378676 0.5637955279763001 0.5728932956373001 1.0 0.8034817959967607 2 Q9H814 1 +G protein coupled receptor activity 0.6653957482715387 0.5634925039434555 0.5730995630558169 1.0 0.8034817959967607 3 Q99720 1 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.3770889853466183 0.5620560869349261 0.5740778061856715 1.0 0.8034817959967607 12 Q8N4Q0,Q9H7Z7,Q9BY49,Q9NZ01,Q14739,Q15392 6 +Phosphatidylethanolamine flippase activity 0.6673244995771047 0.5598152626103793 0.575605452032967 1.0 0.8048238286824587 2 P08183 1 +L serine transmembrane transporter activity 0.6596164692611216 0.5439543167846398 0.5864729097999799 1.0 0.8121620130423942 3 Q96QD8,Q9H9B4 2 +Monosaccharide binding 0.3058926383099087 0.5431229767558521 0.5870451337227873 1.0 0.8121620130423942 28 Q12907,P52789,Q5KU26,Q32P28,P13674,O15460,P49257,O75503,P35613 9 +Udp glucosyltransferase activity 0.427666497849628 0.5384582629284945 0.5902607121170313 1.0 0.8132608643092497 7 Q9NYU2,Q16739 2 +Anion cation symporter activity 0.6565143824027021 0.5335549734832564 0.5936494674015638 1.0 0.8166881150117641 3 Q15043,P55011 2 +L glutamine transmembrane transporter activity 0.6594305046518201 0.5322233296820074 0.5945713266651476 1.0 0.8166881150117641 2 Q96QD8 1 +Protein membrane adaptor activity 0.3992488060786221 0.5304748908270278 0.595782713592778 1.0 0.8168919958660668 10 Q8WXH0,O94901,Q9UH99 3 +Potassium chloride symporter activity 0.6563292923597488 0.5215167804666128 0.6020068190271772 1.0 0.8186553504978301 2 P55011 1 +Cation chloride symporter activity 0.6563292923597488 0.5215167804666128 0.6020068190271772 1.0 0.8186553504978301 2 P55011 1 +Ionotropic glutamate receptor binding 0.4565102964883031 0.5170350287024352 0.6051317065578492 1.0 0.8209600812841387 6 P27824 1 +Protein dimerization activity 0.2465942036347874 0.5121591463645265 0.6085396326368469 1.0 0.8232156598290041 247 P51116,P33897,Q8NAN2,O43707,P09601,Q03164,O00264,Q04837,Q8N2A8,Q9NZJ7,O15217,Q15070,O75027,Q9BRG1,Q14849,Q16706,P06280,Q9BPX6,P16278,P05023,P55327,P07237,Q9Y4Y9,P51648,Q8IYU8,Q8TBA6,Q03518,P22413,P27105,P06865,O95684,Q06787,P07602,Q9UKU0,P22830,Q9NR33,P51114,P30153,Q9Y371,Q99623,O75208,P23246,Q8TCT8,Q07820,Q9UII2,P42892,P62312,O00429,O00560,Q15067,Q99584,Q9Y6J9,Q14108,Q06481,P09493,O95772 56 +Hyaluronic acid binding 0.6529461516774626 0.5099255629757559 0.6101036121549916 1.0 0.8244724966094338 2 Q07021 1 +Camp dependent protein kinase regulator activity 0.6491071900221032 0.5089822940400298 0.6107646350002343 1.0 0.8244724966094338 3 P54619 1 +Chemokine binding 0.6466441060349786 0.5008947337149852 0.6164452090021961 1.0 0.8295879474638427 3 P06756,P05556 2 +Growth factor binding 0.3425673240556218 0.5004363562373315 0.6167678591745318 1.0 0.8295879474638427 15 P06756,Q92896,P98164,O00560,Q99584,Q15375 6 +Phosphatidylserine binding 0.3661468919654617 0.4981641478803434 0.618368349951929 1.0 0.8309508216353082 12 Q06481,Q8WTV0,Q14108 3 +Nuclear localization sequence binding 0.3377867882068794 0.4933538833247445 0.621762561528207 1.0 0.8331382808356183 16 P52292 1 +5 3 dna helicase activity 0.4470787468247007 0.4761605797255688 0.6339599811178667 1.0 0.8407248109482486 6 P18074,P38935,Q9Y230,Q96RR1,P51530 5 +Tropomyosin binding 0.6361010947784447 0.4667711016359055 0.6406636534208459 1.0 0.8430681770939282 3 Q05682 1 +G protein activity 0.3372570250091895 0.4663030691733851 0.6409985821873982 1.0 0.8430681770939282 15 P11233,P62820,P61026,Q9H0U4 4 +Signaling receptor binding 0.2308222590332813 0.4637297053559611 0.6428414118166392 1.0 0.8445873702140617 194 P06756,Q9BQE5,O43707,O75381,P11233,O15258,Q9NZ08,Q9NUQ9,P04439,P05067,P06280,P51572,P23634,Q08431,P07237,P46934,Q92896,P04062,Q9BRK0,Q07954,Q9BUN8,P46379,Q03518,P43490,P22413,Q96RD7,Q07021,O75955,P06576,P62942,O75312,Q9UJZ1,Q92542,P46108,P08236,Q9H2J4,O00560,Q99584,P27824,P01889,Q9BY49 41 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters 0.6385678037778467 0.4617461346019479 0.6442633828472051 1.0 0.8454900439385189 2 Q96QE5 1 +Endopeptidase activator activity 0.4725088518734051 0.4563363550071445 0.6481481249716525 1.0 0.8460605136853213 5 Q9UL46,P61289 2 +Dynein light chain binding 0.6365943050465255 0.4552763053039006 0.6489104705599447 1.0 0.8462749454767942 2 Q86VS8 1 +2 oxoglutarate dependent dioxygenase activity 0.3232978199775768 0.4491588464053263 0.6533170724088437 1.0 0.8500011235573491 19 P13674,P07237,Q32P28,O15460 4 +Endopeptidase activity 0.3163141384455821 0.4425126620807961 0.6581182696738608 1.0 0.8543461941179018 72 Q16740,P67812,P28070,Q9NZ08,Q96TA2,Q96E52,Q92643,O43292,O14773,Q99538,P49721,P28072,Q92905,Q8TCT8,Q9H300,P42892,Q92542,O75844,Q10713,Q2T9J0,Q6NTF9 21 +Opsonin binding 0.5031742525430425 0.440597094433563 0.659504706704874 1.0 0.854938944160224 4 P06756 1 +Serine type endopeptidase inhibitor activity 0.4349278847886956 0.4247871353475547 0.6709918566288327 1.0 0.8614603543145831 6 P05067 1 +Nucleotidase activity 0.4343439721810643 0.4223578280253232 0.6727638547397206 1.0 0.8622833826600584 6 Q9NX62,Q969T7,P49902 3 +Steroid dehydrogenase activity 0.3978733757793281 0.3992393245727595 0.6897168700630183 1.0 0.8737236984236088 7 Q3SXM5,Q53GQ0 2 +Low density lipoprotein particle receptor activity 0.6113519633954624 0.3900989726082025 0.6964633625141556 1.0 0.8791673046338419 3 P98164 1 +Retromer complex binding 0.4551967843953141 0.3900503339849678 0.6964993275579765 1.0 0.8791673046338419 5 P11717,P51149 2 +Long chain fatty acid binding 0.6151677473921693 0.3874379373878273 0.6984320226332899 1.0 0.8808211337131062 2 P52758 1 +Nadp binding 0.3122794476117823 0.3727482354153193 0.709335832750895 1.0 0.8898140100554224 19 P16435,P00374,Q14739,Q13423 4 +N6 methyladenosine containing rna binding 0.4493201039088057 0.3682812956509748 0.7126634978680622 1.0 0.8920197889826613 5 P07910,Q7Z739 2 +Protein n terminus binding 0.2856395096795851 0.3616381944306016 0.7176224187426354 1.0 0.8925526203765778 46 Q9UBU8,O75381,O43707,Q99623,P60228,Q969G3,Q8WVM8,Q9UJW0,O00560,Q15067,Q9BRG1,P40855,Q9Y6X3,Q13190 14 +Phospholipase a2 inhibitor activity 0.5970107163000689 0.3481115087049686 0.7277564415564528 1.0 0.8989702501816563 3 P07355,P04083 2 +Ubiquitin like protein specific isopeptidase activity 0.6005074711023506 0.3437522789248686 0.7310325913797646 1.0 0.8989702501816563 2 Q9P0U3 1 +Glycolipid mannosyltransferase activity 0.596560473639706 0.3323970110839276 0.7395894951808766 1.0 0.900990658697423 2 Q2TAA5 1 +Sterol esterase activity 0.5940231181279887 0.3251912992284748 0.7450362933511823 1.0 0.9018835920571556 2 Q6PIU2 1 +Chemoattractant activity 0.4668547249647317 0.3166849561133664 0.7514826649913549 1.0 0.9047907730566036 4 P26583,P14174,P09429 3 +Epidermal growth factor receptor binding 0.369847543760597 0.2790576975755626 0.7802005464408004 1.0 0.923835793484295 7 P62993,Q92600,O60749,O95219,O00291,P18085 6 +Guanylate kinase activity 0.4498384360274698 0.2639101233491692 0.7918491748141832 1.0 0.9321685377388264 4 Q9UDY2,Q14168 2 +Cytoskeletal anchor activity 0.3635236042287134 0.2537284364777893 0.7997053636608318 1.0 0.9362688830493188 7 Q8TD16 1 +Dynein complex binding 0.3623276778552544 0.2490205366907102 0.8033448957245082 1.0 0.9382955832793212 7 Q06787,Q8TD16 2 +Metalloexopeptidase activity 0.288107378596559 0.2485809054865979 0.8036849801657509 1.0 0.9382955832793212 21 P02786,O75844,O75976,Q9NZ08,Q9NXS2,Q7Z2K6,Q9UIQ6 7 +Single stranded dna endodeoxyribonuclease activity 0.4139390519187287 0.2464140642977703 0.8053617201033914 1.0 0.9385020879116188 5 Q92878,Q9Y2C4,P18887,P49959 4 +Isopeptidase activity 0.329638912622836 0.2432117393176091 0.8078413731988352 1.0 0.9385020879116188 11 P51665,O95630,Q92905,O00303,Q9P0U3,O15372 6 +Calmodulin dependent protein kinase activity 0.4394387057230035 0.2335441667455608 0.8153388774708352 1.0 0.9423291410482292 4 P46020 1 +Calcium independent phospholipase a2 activity 0.5524661476245445 0.2309346309147983 0.8173655862223341 1.0 0.9423291410482292 3 Q8NCC3 1 +Phospholipase a2 activity 0.5524661476245445 0.2309346309147983 0.8173655862223341 1.0 0.9423291410482292 3 Q8NCC3 1 +Metal dependent deubiquitinase activity 0.3575238227820847 0.2303816950170094 0.8177951838920321 1.0 0.9423291410482292 7 Q92905,O15372,P51665 3 +Gtpase inhibitor activity 0.4080135440180541 0.227726490574628 0.8198588769716137 1.0 0.9439384140885544 5 O94813,O00410,P46940,Q13576 4 +Phosphotransferase activity for other substituted phosphate groups 0.3562432159457672 0.2254879181352788 0.82159972330868 1.0 0.9451736654323434 7 Q9NRN7,O14735,Q5H8A4,Q9H9S5 4 +Hsp70 protein binding 0.2892754754756714 0.2134608647345149 0.8309675110551749 1.0 0.9512340433476312 17 Q53FT3,P46379 2 +Nadp retinol dehydrogenase activity 0.3777396316935721 0.2083473319404025 0.8349577768800012 1.0 0.9527945599074208 6 Q6UX07,Q8NBN7 2 +Cobalamin binding 0.5259447264523566 0.1718341530175662 0.8635679146325557 1.0 0.9705707698213392 3 Q99707,Q96EY8 2 +Phosphatidylinositol phosphate phosphatase activity 0.4114632803837812 0.1596303570786545 0.8731722641249129 1.0 0.9752314489663416 4 Q10713 1 +C2h2 zinc finger domain binding 0.4113306667652169 0.1593083353256051 0.8734259539871789 1.0 0.9752314489663416 4 P26368 1 +Phosphatidylinositol transfer activity 0.5194585448392692 0.1586842446983838 0.8739176517945733 1.0 0.9752314489663416 3 Q9H1P3,Q00169 2 +Long chain acyl coa dehydrogenase activity 0.4004057419500427 0.1337351691562573 0.8936119939892795 1.0 0.987138829176108 4 Q9NZ01 1 +Acyltransferase activity 0.2770060561269908 0.1230130923709408 0.9020967304969988 1.0 0.989788280688329 62 P23786,Q96G23,Q8N5B7,Q9NXS2,P49327,Q8NF37,Q9UJ14,Q9UPT9,P27544,Q92604,Q9HCL2,O15498,P50416,O75448,Q96N66,Q8NCC3,Q969G3,Q9NUQ2,O15269 19 +Chaperone binding 0.255738841588538 0.0964460849287435 0.9231662922099948 1.0 1.0 45 P02786,Q16543,Q04656,P98164,O43808,P55011,P01889,Q96KC8,Q14108,Q86TM6,O43615,Q13217,P05023 13 +Translation activator activity 0.3811001410437126 0.0932502489080215 0.9257047554064954 1.0 1.0 4 P11940,Q7Z478,Q9H074 3 +Phosphatidylinositol 3 kinase binding 0.4819988331815857 0.0930705809917637 0.9258474889345668 1.0 1.0 3 P50570 1 +Rna polymerase ii activity 0.4832252607837813 0.0914553882863851 0.927130752613732 1.0 1.0 2 P30876 1 +Protein prenyltransferase activity 0.3754583921015492 0.0825698229004272 0.9341935971496044 1.0 1.0 4 P49356,P53611,P49354 3 +N acyltransferase activity 0.2514672917131476 0.0821638838046219 0.9345163928540984 1.0 1.0 24 P27544,Q96G23,Q969G3,Q9UPT9,Q8N5B7,O75448 6 +Poly pyrimidine tract binding 0.2676998438241244 0.0807880466958917 0.9356105143503874 1.0 1.0 14 P26368,P07910,Q06787,P31943 4 +Poly g binding 0.3313186994064951 0.0737382299640306 0.9412186784646848 1.0 1.0 6 Q06787 1 +Nuclear export signal receptor activity 0.2956791866704182 0.0719472682566529 0.9426438728620724 1.0 1.0 8 O14980,P55060,P62826,Q9HAV4,O15504,Q9C0E2,P35658 7 +Phosphatidylinositol 3 kinase activity 0.4654637722018692 0.069300142794807 0.9447507120788255 1.0 1.0 2 O00443 1 +1 phosphatidylinositol 3 kinase activity 0.4654637722018692 0.069300142794807 0.9447507120788255 1.0 1.0 2 O00443 1 +Cyclic nucleotide binding 0.3417042889390574 0.0590215728277168 0.9529349254306854 1.0 1.0 5 P13861,P41440,P10644,P09543 4 +Calcium dependent protein binding 0.2555410261347306 0.0552911673779421 0.9559064988148434 1.0 1.0 21 Q99584,O76024 2 +Mirna binding 0.2603397875104798 0.0542183805172868 0.9567611766877332 1.0 1.0 15 P98175 1 +Peptidase activator activity 0.2800423179100635 0.050652714699154 0.9596022564486408 1.0 1.0 11 P05067,P61289 2 +Cargo adaptor activity 0.2853107344632806 0.0472238639544513 0.962334808051523 1.0 1.0 9 Q9BXS5,P61966,Q96CW1,P63010,O43747,P53680,O00291,O95782 8 +Cyclin dependent protein serine threonine kinase activator activity 0.4336058641105235 0.0391236671222517 0.968791791777103 1.0 1.0 2 P14635 1 +G quadruplex dna binding 0.3382228490832084 0.0250081829117106 0.9800484366312748 1.0 1.0 4 Q92878,P36776,Q9H2U1 3 +Prenyltransferase activity 0.2765617573635399 0.020099693337687 0.9839638447778204 1.0 1.0 8 P49354,Q86YH6,P37268 3 +Minus end directed microtubule motor activity 0.3958274598252107 0.0167373027460628 0.9866461880358224 1.0 1.0 2 Q8NCM8 1 +Neurotrophin trk receptor binding 0.3946997462644548 0.0162530071323926 0.9870325474591894 1.0 1.0 2 P62993 1 +Neurotrophin receptor binding 0.3946997462644548 0.0162530071323926 0.9870325474591894 1.0 1.0 2 P62993 1 +Integrin binding 0.2494620274523273 0.0162523161309266 0.9870330987257776 1.0 1.0 20 P07237,P06756,O43707,Q03001,P46939,P05556,Q9BX67,P12814,Q08431 9 +Syntaxin 1 binding 0.4120135363790224 0.0159293979848564 0.9872907167749758 1.0 1.0 3 O00186,O75150 2 +Oligopeptide binding 0.3039531392089292 0.0152150371294763 0.9878606251563498 1.0 1.0 6 Q9H7Z7 1 +Jun kinase binding 0.3893431068508619 0.0140775901321928 0.9887680791690572 1.0 1.0 2 O60271 1 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..da96f904d3d40f6126c36ad0234e14111f8f0bc4 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co receptor binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Identical protein binding", "Ige binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 3 4 5 6 pentakisphosphate kinase activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol hexakisphosphate kinase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Natural killer cell lectin like receptor binding", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine flippase activity", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol n acetylglucosaminyltransferase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific endopeptidase activity", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKS1A", "ANLN", "ANO10", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG2B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CENPH", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ5", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAHD1", "FAHD2A", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FNBP1", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL9", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTDH", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NFRKB", "NFS1", "NFU1", "NGEF", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD6B", "OTULIN", "OXA1L", "OXNAD1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPIN1", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE1", "SYNE2", "SYVN1", "TAB1", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM165", "TMEM192", "TMEM201", "TMEM30A", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC21B", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UHRF1BP1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS18", "VPS25", "VPS28", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS52", "VPS72", "VRK1", "VRK3", "VTA1", "VWA8", "WARS", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFPL1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF106", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["AASDHPPT", "ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ACOX1", "ACOX3", "ACP6", "ACSL6", "ACTN1", "ACTN4", "AFG3L2", "AGK", "AGPAT5", "AIFM1", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANO10", "ANXA1", "ANXA2", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2B1", "AP2M1", "AP2S1", "APLP2", "APOL2", "APP", "ARF4", "ARFIP2", "ARHGEF7", "ARV1", "ASNA1", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP6V1E1", "ATP7A", "ATPIF1", "B4GALT1", "B4GAT1", "BAG6", "BCAP31", "BCKDK", "BICD2", "BNIP1", "BSG", "C1QBP", "CACYBP", "CALD1", "CALU", "CANX", "CCDC22", "CCDC47", "CCNB1", "CD47", "CDC37", "CDIPT", "CERS1", "CERS2", "CERS5", "CETN2", "CHMP1A", "CHMP3", "CIRBP", "CISD1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLN5", "CLPP", "CNNM3", "CNNM4", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COPS4", "COPS5", "COQ8B", "COQ9", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPD", "CPNE8", "CPT1A", "CPT2", "CPVL", "CRK", "CSE1L", "CTSA", "CYB5B", "CYP20A1", "CYP51A1", "DAGLB", "DCTN4", "DCUN1D4", "DCUN1D5", "DERL1", "DERL2", "DHCR24", "DHFR", "DHRS1", "DHRS13", "DHX29", "DHX36", "DNA2", "DNAJA2", "DNAJC1", "DNAJC10", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DPAGT1", "DPM1", "DST", "DYNC2H1", "ECE1", "EFCAB14", "EHD1", "EHD4", "EIF3E", "EIF3F", "EIF3H", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "ENPP1", "EPDR1", "EPHA7", "ERAP1", "ERC1", "ERCC2", "ERLIN2", "ERMP1", "ERO1A", "ERP44", "ESYT2", "ETFDH", "EXOC4", "EXOG", "EXT2", "FADS1", "FADS2", "FAF2", "FAM49B", "FASN", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP7", "FKBP9", "FKRP", "FLII", "FLOT1", "FMR1", "FNTA", "FNTB", "FOXRED1", "FTO", "FUCA2", "FUNDC2", "FXR1", "FXR2", "GAA", "GALNT1", "GALNT2", "GALNT4", "GBA", "GDE1", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLCE", "GLG1", "GM2A", "GNS", "GOLGA5", "GOLPH3", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GRB2", "GSTA4", "GTF2E1", "GUSB", "HADH", "HEXA", "HEXB", "HGS", "HIKESHI", "HIP1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMGB1", "HMGB2", "HMGCR", "HMOX1", "HMOX2", "HNRNPC", "HNRNPH1", "HOOK2", "HOOK3", "HPS6", "HS2ST1", "HSD17B12", "HSDL1", "HSDL2", "HSP90AA1", "HSP90B1", "HSPA13", "ICMT", "IGF2R", "IGHMBP2", "IMPAD1", "INA", "IPO4", "IPO5", "IPO9", "IQGAP1", "IQGAP2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "JAM3", "KCTD21", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KIF14", "KMT2A", "KPNA2", "LAMP1", "LBR", "LDAH", "LETM1", "LGALS3BP", "LGMN", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LSM5", "LSM6", "MAN1A2", "MAN2A1", "MAN2B1", "MAU2", "MBOAT7", "MCL1", "MCUB", "MED24", "MFGE8", "MFSD3", "MGAT1", "MIA3", "MICU1", "MICU2", "MIF", "MIGA1", "MMAB", "MMGT1", "MORF4L1", "MPC2", "MPP2", "MRE11", "MSMO1", "MTAP", "MTCH1", "MTR", "NAGLU", "NAMPT", "NCEH1", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA13", "NDUFA8", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NEDD4", "NEDD4L", "NEFL", "NEO1", "NLN", "NNT", "NPC1", "NPC2", "NPEPPS", "NSD3", "NT5C2", "NT5C3B", "NUCB1", "NUCB2", "NUP107", "NUP160", "NUP205", "NUP214", "NUP35", "NUP54", "NUP88", "NUP93", "NUPL2", "OMA1", "OPA1", "OS9", "OSBPL2", "OSBPL8", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PAIP1", "PANX1", "PARL", "PCYOX1", "PCYOX1L", "PDCD5", "PDCL3", "PDK1", "PDSS2", "PECR", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHKA1", "PIGG", "PIGK", "PIGU", "PIK3C2A", "PITPNA", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLXNB2", "PMPCA", "PNPLA8", "POLE2", "POLE4", "POLR2B", "POR", "PPP2R1A", "PPP2R1B", "PPP4R3A", "PPT1", "PPT2", "PRCP", "PRELID1", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKRA", "PSAP", "PSMB2", "PSMB4", "PSMB6", "PSMD7", "PSME2", "PSME3", "PTGES2", "PTPRF", "QPCTL", "QSOX2", "RAB10", "RAB1A", "RAB1B", "RAB32", "RAB34", "RAB7A", "RABGGTB", "RAD50", "RALA", "RAN", "RANBP6", "RANGRF", "RBM10", "RCN2", "RDH13", "REEP2", "REPS1", "RER1", "RFT1", "RHBDD2", "RIDA", "RNF14", "RNF40", "RPN1", "RPN2", "RPS6KA1", "RRM2B", "RUVBL2", "S100A13", "SC5D", "SCARB1", "SCARB2", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SENP1", "SET", "SFPQ", "SFXN1", "SFXN2", "SH3GLB1", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SMARCE1", "SNAP29", "SNAPIN", "SNX2", "SNX27", "SNX4", "SPAG9", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRP68", "SSBP1", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STIM1", "STOM", "STOML2", "STT3A", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STXBP3", "SUN1", "SUN2", "SURF4", "SV2A", "SYNE2", "SYVN1", "TAF6L", "TAP1", "TECR", "TEFM", "TFRC", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8B", "TJP2", "TMCO1", "TMED10", "TMEM165", "TMEM192", "TMEM201", "TMEM30A", "TMPO", "TMTC3", "TMX3", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOR1AIP1", "TPD52", "TPM1", "TPM4", "TPP1", "TPR", "TRAM1", "TSPO", "TTYH3", "TUBGCP2", "TUBGCP4", "TWNK", "TXNDC12", "TYSND1", "U2AF2", "UGCG", "UGGT1", "UGT8", "UNC119B", "UQCR10", "UQCRC2", "USP22", "UTRN", "UXT", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS52", "WDR43", "WFS1", "XPO1", "XPO4", "XPO5", "XRCC1", "XRCC6", "YKT6", "YME1L1", "YTHDF3", "YWHAE", "ZADH2", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_hp/advanced/idx2term.json b/msigdb_hp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4cd29a06154752dc1dab3647e95e7947e96d9fbc --- /dev/null +++ b/msigdb_hp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Cognitive impairment", "1": "Muscle abnormality related to mitochondrial dysfunction", "2": "Sensorimotor neuropathy", "3": "Abnormal retinal artery morphology", "4": "Abnormal circulating cholesterol concentration", "5": "Hepatomegaly", "6": "Abnormal biliary tract morphology", "7": "Biliary tract abnormality", "8": "Dementia", "9": "Scotoma"} \ No newline at end of file diff --git a/msigdb_hp/advanced/plot_0.png b/msigdb_hp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..29323e9b7f28b9ba006253cdd9d4e2c9f6913eff --- /dev/null +++ b/msigdb_hp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cba6b9bda7587ec1a0c888ec6399cd57e2288b3297bf18be8021cf0d4a469c97 +size 219126 diff --git a/msigdb_hp/advanced/plot_1.png b/msigdb_hp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0059eeb71b02a4c4a06de58b0665d4f8d9d7d3cd --- /dev/null +++ b/msigdb_hp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b1cf64dc2952f879b8c6f6108047a60eb8508d02307afe6a64e9a823a5ec30f +size 211366 diff --git a/msigdb_hp/advanced/plot_2.png b/msigdb_hp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0a0837925015ae6d4a4d31c319516f6bbed935b2 --- /dev/null +++ b/msigdb_hp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4b9c41d413be610e51c85bfd87ea80854baecd82b6d4aa52bcab2481f45be8b +size 204676 diff --git a/msigdb_hp/advanced/plot_3.png b/msigdb_hp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..1eeb2954adea53a4d3a2944d8563021ded4d7de2 --- /dev/null +++ b/msigdb_hp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:872730839e92a94625f16515574917d59c5c21c6dad1f5039646f1445e331307 +size 197904 diff --git a/msigdb_hp/advanced/plot_4.png b/msigdb_hp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..06b07defc06e53503822d1953ad52dc6fe2bcbca --- /dev/null +++ b/msigdb_hp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:740716e09bf50492418fbab0805ec235d5d8c43e4605674962b9bc5201a787a6 +size 205762 diff --git a/msigdb_hp/advanced/plot_5.png b/msigdb_hp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..453ac3654d3c4f6d1b94ad0dd96b9f95643a49ed --- /dev/null +++ b/msigdb_hp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9311770aafb0a5215907e5374b6ed9badbaaa885686736f74d4997f2eec0bfc2 +size 215182 diff --git a/msigdb_hp/advanced/plot_6.png b/msigdb_hp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..7ca962e73fa4d8580458fae30a400225d4604b9e --- /dev/null +++ b/msigdb_hp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6095e7791f4e03e99b53b9be75a49d0fb4e4a7cc5b67153588edad5c1f779829 +size 202174 diff --git a/msigdb_hp/advanced/plot_7.png b/msigdb_hp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e3ea890aecf067cbe36402e6516fc7263ed9d970 --- /dev/null +++ b/msigdb_hp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:153a68711cc6ba23be7e7df78ccba6812f2034e69f1ade61f74ccb190bdf43a2 +size 201068 diff --git a/msigdb_hp/advanced/plot_8.png b/msigdb_hp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..6968ba157bf227debd7062393a770bd20c24f46b --- /dev/null +++ b/msigdb_hp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:05ac38f4543a8f320cbd2d10c98356c3dd0b6f5cf83faad0c88c2819c1ec7c64 +size 206584 diff --git a/msigdb_hp/advanced/plot_9.png b/msigdb_hp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..af8a398ed9f2ed3d22dc528da9052f6d28a2ecb7 --- /dev/null +++ b/msigdb_hp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64dea5807b217f1e23db190e46ed1ea1f1dd3c206020b6fd51d629e5d12e6731 +size 193801 diff --git a/msigdb_hp/basic/idx2term.json b/msigdb_hp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4b1d2c06b52bccbf04567baa6b00ce0ba670b6cf --- /dev/null +++ b/msigdb_hp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Cognitive impairment", "1": "Muscle abnormality related to mitochondrial dysfunction", "2": "Sensorimotor neuropathy", "3": "Abnormal retinal artery morphology", "4": "Abnormal circulating cholesterol concentration", "5": "Hepatomegaly", "6": "Abnormal biliary tract morphology", "7": "Biliary tract abnormality", "8": "Dementia", "9": "Scotoma", "10": "Bulbar signs", "11": "Abnormal cellular phenotype", "12": "Muscle stiffness", "13": "Central scotoma", "14": "Optic atrophy", "15": "Abnormality of corneal stroma", "16": "Abnormality of head blood vessel", "17": "Abnormal tissue metabolite concentration", "18": "Left ventricular hypertrophy", "19": "Mitochondrial myopathy", "20": "Ventricular arrhythmia", "21": "Cherry red spot of the macula", "22": "Mental deterioration", "23": "Ragged red muscle fibers", "24": "Disproportionate short stature", "25": "Elevated pulmonary artery pressure", "26": "Horizontal nystagmus", "27": "Morphological abnormality of the pyramidal tract", "28": "Delusions", "29": "Abnormality of pulmonary circulation", "30": "Ventricular hypertrophy", "31": "Macular degeneration", "32": "Hyperlipidemia", "33": "Abnormal auditory evoked potentials", "34": "Impaired proprioception", "35": "Abnormal csf protein level", "36": "Peripheral demyelination", "37": "Polyneuropathy", "38": "Clumsiness", "39": "Postural tremor", "40": "Macroglossia", "41": "Focal white matter lesions", "42": "Toe walking", "43": "Optic neuropathy", "44": "Abnormality of the optic nerve", "45": "Global brain atrophy", "46": "Impaired vibratory sensation", "47": "Abnormal enchondral ossification", "48": "Ankle clonus", "49": "Resting tremor"} \ No newline at end of file diff --git a/msigdb_hp/basic/plot_0.png b/msigdb_hp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b32659a6f1a6d19afb92775f98cf9dcf397dc240 --- /dev/null +++ b/msigdb_hp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d55c6d746cb4cf25668e28bf04fd9565ba484803919b5575b4953e2fcc55be77 +size 148658 diff --git a/msigdb_hp/basic/plot_1.png b/msigdb_hp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..3940a56b91500e3881e286e60b9ff08c7356a897 --- /dev/null +++ b/msigdb_hp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:114d18be90ab173773a78096005674ffcf312d49111231ffa9079dc12c86c3c7 +size 148179 diff --git a/msigdb_hp/basic/plot_10.png b/msigdb_hp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..35d37ae27b4a47fdf284d0bd63f70d83698310f4 --- /dev/null +++ b/msigdb_hp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7acf55c349e8a05958c06a1cea86124c2a56d8ebf9962e533285796cc6c45e5e +size 138298 diff --git a/msigdb_hp/basic/plot_11.png b/msigdb_hp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..cddad0990ccb5ed1d758ef31d46fb1772637f17c --- /dev/null +++ b/msigdb_hp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1528aae1285ab015fd15104f32289b15edf7a4d7b14b4899c743769fdcb891f7 +size 147432 diff --git a/msigdb_hp/basic/plot_12.png b/msigdb_hp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..388515d489e8f013de5c90f8ac441a21bfce7ab7 --- /dev/null +++ b/msigdb_hp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fd8c8548698c07fc0ce0545726a803ef7fc4613f87cbf8a71de5fd2e60af08b9 +size 142192 diff --git a/msigdb_hp/basic/plot_13.png b/msigdb_hp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..b8c674ec079b08fd811265f7f5a32118e9b8219e --- /dev/null +++ b/msigdb_hp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c90dea83f4c7f2ea455dc94721bc1531a0e7d980162ccbe2fdb259cb0a292262 +size 140892 diff --git a/msigdb_hp/basic/plot_14.png b/msigdb_hp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..a1fa4edb6eed61277a30c915b0abed95f5d9cd4b --- /dev/null +++ b/msigdb_hp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a1b63cbd13ac5a0e743b6a634809af207f023788ca58bd8aa1c217f425c3b5f +size 144642 diff --git a/msigdb_hp/basic/plot_15.png b/msigdb_hp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..b304c2d1c232af15cd49bcabf0004c28bc1dd877 --- /dev/null +++ b/msigdb_hp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f821e0cb9e29ea6196080e97d6acaf1e205c93614349645c9d71381fe8a575dd +size 144238 diff --git a/msigdb_hp/basic/plot_16.png b/msigdb_hp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..f41df12b416ecb300b67607092e90f5abad3ec41 --- /dev/null +++ b/msigdb_hp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c0a4504eb8be1cb7701d2d7f99c916a96f860f8d27974da02d218b18621990da +size 146114 diff --git a/msigdb_hp/basic/plot_17.png b/msigdb_hp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..6eec4ac4f539d0096e3e98f17d2610750189b208 --- /dev/null +++ b/msigdb_hp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:235b4637e016ca7a6a49803167c26e43620ec4c0bb1b6ee854c4c4050b9a81e1 +size 150626 diff --git a/msigdb_hp/basic/plot_18.png b/msigdb_hp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..267eeaedcf706295dc55759af9de2a5bcf500bc5 --- /dev/null +++ b/msigdb_hp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ef89d8fc0f612792578cd64672e60d4a677b2a132bcadecee8344bc432722f6 +size 142504 diff --git a/msigdb_hp/basic/plot_19.png b/msigdb_hp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..568c02baf96a672c184bb7b7c8b2a1f1108e966b --- /dev/null +++ b/msigdb_hp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f28ddfd86059034068a34cd2b2247f1f02a9fb70d0975395fe8d2972207c994d +size 140839 diff --git a/msigdb_hp/basic/plot_2.png b/msigdb_hp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..7683f1fb01aad0a1a2b4d2adcfa890b4f824a03d --- /dev/null +++ b/msigdb_hp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae4dcc7be0d9d0d69c9af2fb577b8011d5dd8dab5af11d9162a1b204b5bdf053 +size 142726 diff --git a/msigdb_hp/basic/plot_20.png b/msigdb_hp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..e8e488c5b53511eb0fbc57fe7b116390f76757a1 --- /dev/null +++ b/msigdb_hp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:04e6789b2965b22e363802d46522949c2559265d5a026c1eaa7b427f7329c0bb +size 143915 diff --git a/msigdb_hp/basic/plot_21.png b/msigdb_hp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..cdbb5eb97b7e9f572a749c634cb2ad3798d9e0d7 --- /dev/null +++ b/msigdb_hp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56411277690aaf6b01411ae8eb36b4b89bcf2c55eb859a2c7d157e7dcd8c9e4e +size 144595 diff --git a/msigdb_hp/basic/plot_22.png b/msigdb_hp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..adc10a47034acbfd07618dfb3b46f01338f64b0f --- /dev/null +++ b/msigdb_hp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:65702d1871f87b9a549703081ce092e114bc64ed30f017631c40cc44f3e0c6d6 +size 147451 diff --git a/msigdb_hp/basic/plot_23.png b/msigdb_hp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..51cda7def40f5c1cf62fda00c22e30d6029a8bc2 --- /dev/null +++ b/msigdb_hp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:68bf2f84654a64a7b66cfb2705647748664fb83f59ed225a647e861a44c7aa59 +size 145241 diff --git a/msigdb_hp/basic/plot_24.png b/msigdb_hp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..1720dcae09cb78b6821b81dea1ce1fd38da64fdc --- /dev/null +++ b/msigdb_hp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb8c9b851a47a81b6690c8c67e44655bab3478987d5d834a9a91f7c65c0cd34d +size 144268 diff --git a/msigdb_hp/basic/plot_25.png b/msigdb_hp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..ba9b0e9217bb81130bb14996b6b11bafcc6fae8a --- /dev/null +++ b/msigdb_hp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9cd67bc46379e2721b3185618172d0632343e35061af325173eae84f40e1c81e +size 146876 diff --git a/msigdb_hp/basic/plot_26.png b/msigdb_hp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..37650b3ee1fbcaa01d2dab06e9f71fca70f0b276 --- /dev/null +++ b/msigdb_hp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4a8986aaba70eb57b26d7b645a6e7953be455fad4635dae065c28869490400d +size 141709 diff --git a/msigdb_hp/basic/plot_27.png b/msigdb_hp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..a720ee04cc165ef68a3788b1d0e41b693142f579 --- /dev/null +++ b/msigdb_hp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f26bf2ce8914921a850f02bd9f0ea3bdbf609229b00b667d8e4f639098722889 +size 151046 diff --git a/msigdb_hp/basic/plot_28.png b/msigdb_hp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..ee6c829ae5f5b7ebdacf8908fbd6144df0fc154d --- /dev/null +++ b/msigdb_hp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:274f96b72723c0e87c29a57a5194be75743ae02396fbe8074c7d48182d9df041 +size 136999 diff --git a/msigdb_hp/basic/plot_29.png b/msigdb_hp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..9bb42f337c0fb1e7cfa1087bc308c9fa7a08ad21 --- /dev/null +++ b/msigdb_hp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17b3c681d0ec7c0e24f6db4dfc820cb03fa3d1c3f685b850206bc7f52b73324b +size 145956 diff --git a/msigdb_hp/basic/plot_3.png b/msigdb_hp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..830bbd2026e26f6a23d3e122d23fe5812947b353 --- /dev/null +++ b/msigdb_hp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da081068e458c7a5cd9913598a0b6556889a04b3e31939b4aa1b2fcdbe88e6d8 +size 148984 diff --git a/msigdb_hp/basic/plot_30.png b/msigdb_hp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..5bd53e05bad995563bd776fbf5ce458d47ce60f1 --- /dev/null +++ b/msigdb_hp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7aa90441924f88afe132eeb6accef8110d394718780e3ed79598b8425d6a4752 +size 142187 diff --git a/msigdb_hp/basic/plot_31.png b/msigdb_hp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..9d4910635b9795d071d3fcb6cc4933b27eee5979 --- /dev/null +++ b/msigdb_hp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:46e92472b05923045ea0ca5d2ac6428cf44d67237e6579ef2b0057b01a708f78 +size 139923 diff --git a/msigdb_hp/basic/plot_32.png b/msigdb_hp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..4aa9188b735525253cbd2a84727e6daee6f635e0 --- /dev/null +++ b/msigdb_hp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8867a907b283ef3288d49041add39ab0c34b156d7c23707720534c93ab9749e3 +size 144431 diff --git a/msigdb_hp/basic/plot_33.png b/msigdb_hp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..290e249970546a0222fcf341c777e15881813027 --- /dev/null +++ b/msigdb_hp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50bc9592c31647937762b121feddfa04b2c8bfc83fd46fd39886d8057317dbf2 +size 147558 diff --git a/msigdb_hp/basic/plot_34.png b/msigdb_hp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..3116c7ab390e4a06912923b939fd04df8a84ce2c --- /dev/null +++ b/msigdb_hp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f9d17cbf2f620d82feb1d9313c50fc222efb1cc4db6df39935329eab3aa0618 +size 148945 diff --git a/msigdb_hp/basic/plot_35.png b/msigdb_hp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..232b014e8d7cbfcf1009f06292b01d714837f190 --- /dev/null +++ b/msigdb_hp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5654a376cedc95a6f2ce06ed49640df14220614a17676ba1f096aa4378d93005 +size 140937 diff --git a/msigdb_hp/basic/plot_36.png b/msigdb_hp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..449fb3f1acca0c3a94c4a702878476dd585ecfef --- /dev/null +++ b/msigdb_hp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7795cf35a6a97ba9488e1688456b1aa81289304ab4d85ff23e617247b5720ede +size 139639 diff --git a/msigdb_hp/basic/plot_37.png b/msigdb_hp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..6e7ed7718b6b1f2fb5481adf4192672ce82f187a --- /dev/null +++ b/msigdb_hp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3adb45305700a90b94ed322b94a9f0f1223f6fa2f0f37d195b7e25533063c91f +size 137803 diff --git a/msigdb_hp/basic/plot_38.png b/msigdb_hp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..dbc853d0b50d0216e386b0abfd8445458d508d63 --- /dev/null +++ b/msigdb_hp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88205bf840a606492b9410238e9345983bbe29fe2c20f67ff52d551d6a0d957b +size 137643 diff --git a/msigdb_hp/basic/plot_39.png b/msigdb_hp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..f492d3225846a61e7bfbff8a0313ae094539c981 --- /dev/null +++ b/msigdb_hp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6e84b0b87ba9899755bf995ace0d87cbda3750f3b4b31e71340d2ac6a05b23e6 +size 138325 diff --git a/msigdb_hp/basic/plot_4.png b/msigdb_hp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ef7cca8260422d9713065d30e427d47862b3c016 --- /dev/null +++ b/msigdb_hp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e9e7cf00b2150693ca76e6ddf7490baf02ba1ebc7d6cfdbfb7ff610d3c898d2 +size 149488 diff --git a/msigdb_hp/basic/plot_40.png b/msigdb_hp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..b11be0d64f53f7ea2c23e6b8be216caa244af7ed --- /dev/null +++ b/msigdb_hp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b4e9697aabe1ff24d0364163aa95211827f080f11088b0cf9336a062ad65f78 +size 144253 diff --git a/msigdb_hp/basic/plot_41.png b/msigdb_hp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..c806162d44b93d73e3dfd897a52af4b222f5aec6 --- /dev/null +++ b/msigdb_hp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d55bd69f2fca63b6a5c14aabe766393c70051d9caa1e5055be9c1b276f7c82ed +size 137775 diff --git a/msigdb_hp/basic/plot_42.png b/msigdb_hp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..79359b6806faa5325a029bd4b6017744396bc117 --- /dev/null +++ b/msigdb_hp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:426eb55daf08856aad287b6816b4b9031db00a6ae052b169effe36c294f8af05 +size 134508 diff --git a/msigdb_hp/basic/plot_43.png b/msigdb_hp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..1030b6e3d229602a6f4c980471cd4ac08272ed53 --- /dev/null +++ b/msigdb_hp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8f158c84f7f3e52024e6bdb7e5c76f5879e4c1c85a848055ecf32855fc89d856 +size 135686 diff --git a/msigdb_hp/basic/plot_44.png b/msigdb_hp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..2f33adef6d3f956eeaa455dcc5d445eccd4d8684 --- /dev/null +++ b/msigdb_hp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f37cff48b7b85ca55606f423af13cb693145e6294786a8fd59d4119621ff94fd +size 147947 diff --git a/msigdb_hp/basic/plot_45.png b/msigdb_hp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..a2733148a4fa66ff841f35a56f4fa61a0505c15b --- /dev/null +++ b/msigdb_hp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a18f08da02dfee2faa3738b47dfe6465b95be384b86dd84bdd4a6574f6076d6d +size 137760 diff --git a/msigdb_hp/basic/plot_46.png b/msigdb_hp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..211a571f37c9b1ab4467253de6d942b2b6a2247b --- /dev/null +++ b/msigdb_hp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:753a2199cc62729592cb6aff4c6ed9880c63d0310bba3127d1f4cc2eb196c3e7 +size 149010 diff --git a/msigdb_hp/basic/plot_47.png b/msigdb_hp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..d0fd95fe70acc27059443a8b93e143f8a1737c17 --- /dev/null +++ b/msigdb_hp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5ac0c440e6ffd49f9d6f6ae073c5fd40e78b4f51d1474a10cb5e92ea76896c8 +size 142396 diff --git a/msigdb_hp/basic/plot_48.png b/msigdb_hp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..8cc708d12d4f78d9a97304f099fa36e427682ed1 --- /dev/null +++ b/msigdb_hp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:37152ce6c99305e87c9dd119ed577c0e8ec36c29d9109bc22639b41553f3c178 +size 133589 diff --git a/msigdb_hp/basic/plot_49.png b/msigdb_hp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..c99f7f3ba8d13c7c8847a43aba4ab410af6543f9 --- /dev/null +++ b/msigdb_hp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66c345e0f409067cb432a8049ad5cb9c82392b91a26079a095b01445f5699eb6 +size 132438 diff --git a/msigdb_hp/basic/plot_5.png b/msigdb_hp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..1002256677d4195a98d624ef24c8e6c7c1fc4e84 --- /dev/null +++ b/msigdb_hp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:096a3c57b37838229212d1ea05904cad4dceef232093928921b52d2f2e6bc7b4 +size 143482 diff --git a/msigdb_hp/basic/plot_6.png b/msigdb_hp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..21a4163127e7e774ff89358eb8900917f03c6ba5 --- /dev/null +++ b/msigdb_hp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c92e411a047cd4c900d3a1b7f62afefacaa52e07e0b6049aa4a85d69dfa48994 +size 145488 diff --git a/msigdb_hp/basic/plot_7.png b/msigdb_hp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..1e03b01400701d6cbf10d4a91e0e863dab352a11 --- /dev/null +++ b/msigdb_hp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9bff80b51a3a9eaea1a595dd3087de0569c16b1e809e85c70b3509f19a6db8a4 +size 141650 diff --git a/msigdb_hp/basic/plot_8.png b/msigdb_hp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..4c573562cb51e60d2995ef2f07ec9860cb1acaf3 --- /dev/null +++ b/msigdb_hp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ccb0ab7d90b3051bedae7eccb0a5b736e44c21d21849c7284b207dfc18389f96 +size 136980 diff --git a/msigdb_hp/basic/plot_9.png b/msigdb_hp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..57455225c072170e00102ee755c8cf06050aae37 --- /dev/null +++ b/msigdb_hp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:19a82f7f45c39f85ed671744452e2564b3ef8a3a34bba80b06f47f5a2f3f08ad +size 135241 diff --git a/msigdb_hp/consensus.joblib b/msigdb_hp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..697624eea06205b9c86d50c4014004ecd95cd8ad --- /dev/null +++ b/msigdb_hp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb93c3bbee4f872e09c7ffc9d53f7b52f4fe05a19640d13e535afe69c068e233 +size 304175 diff --git a/msigdb_hp/df_merge.tsv b/msigdb_hp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d29bf33c2eeecc626138c6e32cb88ce242371cf6 --- /dev/null +++ b/msigdb_hp/df_merge.tsv @@ -0,0 +1,192 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cognitive impairment 55 183 4.63414793664027 3.5841062908659183e-06 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 6.851937069715587e-09 0.0182460126638103 0.0674626072880623 4.264120216897049e-07 1.419791282798302e-09 +Muscle abnormality related to mitochondrial dysfunction 14 40 3.297128231275752 0.0009767889389262 11.12378640776699 35.58252427184466 0.9791864828781052 0.3365990386989574 4.6259837298613 4.333263242301439 1.4740065920951253 0.3430734831138388 3.684053612847274e-07 0.003639941270827 3.855573870712357e-05 3.717069426665352e-06 4.420299325281492e-07 +Sensorimotor neuropathy 13 39 3.252750477214712 0.0011429381370515 8.980582524271844 31.118932038834952 1.3016328701661894 0.3009249972125085 3.646997920951252 3.5836645053134393 1.2437208862143418 0.3260038325488978 0.0001083252985717 0.0427950226871739 0.0045315560193572 0.0002733113837236 2.7099978231798197e-05 +Abnormal retinal artery morphology 9 24 3.205797339178848 0.0013468881213167 6.985436893203883 21.733009708737864 0.6882820766413594 0.2247118762866906 2.318097134221824 2.0518941450352677 1.8438290687413053 0.2835525492265039 0.0001066444926868 0.0016433207319124 7.631546446868991e-06 2.3584197917317812e-05 0.000119970094136 +Abnormal circulating cholesterol concentration 17 35 3.196672603861024 0.0013902262245422 9.691747572815531 31.70873786407767 0.976903841313624 0.2790879029908041 4.4525142732793395 3.04459115485426 1.5883623188049951 0.3063455707490317 0.0002139281419048 0.2989716991852097 0.0353550186833354 0.0021979061624995 0.0002439853208345 +Hepatomegaly 45 189 3.1899166236656877 0.0014231384518605 39.728155339805824 169.55582524271844 0.4089837357771489 0.5280564448988146 14.21621812446184 16.25283515367601 1.2317505616434137 0.3902252758923212 8.29843558614828e-09 0.0090611948561073 0.001155404431858 2.1173384815712416e-05 1.294103668171026e-08 +Abnormal biliary tract morphology 7 25 3.164255341704057 0.0015548032211594 7.427184466019417 23.174757281553397 1.329418499193971 0.249884151345828 2.8924137189053876 2.044064029481889 1.3393824039546371 0.2984385007787948 0.0008379070631066 0.2217755071466549 0.0919415891551245 0.0016834035897202 0.0009271037060534 +Biliary tract abnormality 10 28 3.130705631927178 0.0017438686400572 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 0.0002037058670518 0.2613604367755145 0.1258733376055511 0.0044093100996901 0.0002305240226419 +Dementia 26 65 3.0994509464497377 0.0019387967981161 17.021844660194176 58.19174757281554 0.9978727756866732 0.3214313161707923 5.814027938449679 5.568168011495494 1.793982160512653 0.3770196158976925 6.220460420591913e-09 0.0264449596361177 0.0101994394473641 2.6804136541097984e-05 1.732420432829773e-09 +Scotoma 8 14 3.034396356236014 0.0024101755320942 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.0005225221975125 0.1723099894081314 0.0065760397653667 0.0003658042695641 0.0001003888941435 +Bulbar signs 7 13 3.0058711016406585 0.0026482123096904 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0001002043673363 0.1403531442218371 0.0034893000144238 0.0009447024772989 0.0001106790733064 +Abnormal cellular phenotype 46 203 3.0012203034658147 0.0026889994407801 39.61407766990291 185.5461165048544 0.5974508379603953 0.5924097878960474 13.622479133459526 17.10902530988799 1.1142688852015548 0.3995331163327372 2.687797077431698e-06 0.0035337166892611 1.2211832075003066e-05 4.379287421585406e-07 6.530512620483946e-07 +Muscle stiffness 9 26 2.9515559540552587 0.0031617725474146 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.0002448403174687 0.2291240669446297 0.0978881295505725 0.0020419820824666 0.0002745691183549 +Central scotoma 6 11 2.931891174258937 0.0033690478112453 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0002146879073638 0.1197698958477507 0.0021303683071518 3.671693537728937e-05 2.8968816708506228e-05 +Optic atrophy 43 210 2.9178224962293053 0.0035248494085788 39.97330097087379 184.7135922330097 0.2254846155090266 0.7235761385556879 12.871537267469767 19.604722774296683 0.8047704019364031 0.3342405671672314 8.903813863162157e-06 0.663029939395824 0.0869103360432668 0.000531352672187 5.730259116956277e-06 +Abnormality of corneal stroma 6 16 2.914159075016961 0.0035664812152813 4.733009708737864 13.131067961165048 0.6716440045814968 0.2233795964932449 1.7589100966397004 2.506749302052849 1.61853564814875 0.2527544669587041 0.0220749570316637 0.2436179272361805 0.1100932826860655 0.0138556470380734 0.0236488585480569 +Abnormality of head blood vessel 9 27 2.8911498770957107 0.0038383501948424 7.512135922330097 24.881067961165048 0.5951213621611695 0.2501622891395578 2.541375726543966 2.628804376839775 1.8399520883426277 0.3043503409762604 0.0005091182282876 0.002776216406037 2.225319400554361e-05 9.122299302310884e-05 0.0005691535672401 +Abnormal tissue metabolite concentration 7 17 2.880067830935514 0.0039758962110512 5.895631067961165 14.650485436893204 0.4799987914691458 0.2340469593783387 2.3926019349714145 2.328417679576543 1.7567023743300048 0.2768423789344761 0.000126786672537 0.1444128696349771 0.0398064357050217 0.007920049564759 0.0001399534495659 +Left ventricular hypertrophy 13 28 2.8718870746678 0.0040802874388896 7.567961165048544 23.54126213592233 0.6997255266541987 0.4097452846499351 3.537969183053948 3.034709621147107 1.2051726960058406 0.3398649994618895 0.0011016518720815 1.0 0.1323300889211223 0.0756483536674149 0.0012269776587721 +Mitochondrial myopathy 12 33 2.858905106199712 0.0042510593024776 9.186893203883496 28.17233009708738 0.8747125393417822 0.3473011798108487 3.936575202939786 3.974666305559559 1.3336232032537867 0.3216890657230479 6.892295060503936e-07 0.0247821522094747 0.0015259573241502 3.17049669247141e-05 8.098337647809127e-07 +Ventricular arrhythmia 17 45 2.843916360933299 0.0044562744012519 10.0 36.96601941747573 1.0415384316890377 0.3677574027458479 3.8522468541414527 4.8022861343455805 1.0152201826292362 0.3231502492090489 0.0031632192003993 0.3805737292783386 0.0161157889533151 0.0030790050493254 0.0035492595045612 +Cherry red spot of the macula 6 9 2.825495758794603 0.004720751295193 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 3.5921643232053493e-07 0.0013899505248691 3.74476751148508e-06 5.522373670119844e-06 3.957975029002194e-07 +Ventricular preexcitation 4 8 2.825313177782559 0.0047234423881867 2.5145631067961167 6.497572815533981 0.9841118497305948 0.2225227126053997 1.468861772329754 1.5757549992030588 1.3097679632537274 0.2453287763295943 0.001650969453088 0.0858288536093336 0.0007461625149634 0.0009779431698101 0.0017585862412997 +Mental deterioration 38 105 2.821771164871412 0.0047759242467648 26.16990291262136 97.51699029126212 1.0638646072845834 0.3178098854339388 8.217921866043707 8.355116022963852 1.9487627742005753 0.3762024781602087 1.896871351904448e-09 0.0058693396321768 0.0096006639063748 1.3032669254068225e-07 7.596168270849103e-10 +Ragged red muscle fibers 6 22 2.813413811998006 0.0049018524764876 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 0.0022588883215701 0.0143944751365022 0.0061250241039257 0.0003172858283449 0.002448268499096 +Disproportionate short stature 16 29 2.797463144438327 0.0051505643053189 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.0034061213326875 0.344137720202208 0.5782406044087871 0.0207913960921613 0.0037949128027229 +Elevated pulmonary artery pressure 15 29 2.7893474919525443 0.0052814364121946 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.0630984011439449 1.0 0.2107495506364678 0.0207913960921613 0.0673966042860956 +Horizontal nystagmus 11 27 2.789256840013736 0.0052829150668947 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.0009636625081053 0.225458320485449 0.0017566671607845 0.0018561414510811 0.0002346698535802 +Progressive sensorineural hearing impairment 4 11 2.766113397125295 0.005672880451621 3.1092233009708736 10.177184466019416 0.6816533912969537 0.4125027093829873 1.9409267075593708 1.400472817159746 0.9707665840558262 0.3067183945172701 0.0070806679302259 1.0 0.2223047329091382 0.0033024410276518 0.0075122167669424 +Morphological abnormality of the pyramidal tract 10 23 2.759089393285749 0.0057962676947749 5.978155339805825 21.21359223300971 0.941567362517309 0.4190895040605777 2.5839325217273803 2.130000617333851 0.9433759961177594 0.3444076850385922 0.0666748062072547 0.2471994937249445 0.4407605172427877 0.0148252690690975 0.0704094801772502 +Delusions 7 21 2.7564435648479506 0.0058433695364539 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0001974885348412 0.1524760813950871 0.0443091130960601 0.0001711644149485 0.000217728528826 +Abnormality of pulmonary circulation 17 34 2.7216257651742963 0.0064961661515925 8.439320388349515 28.538834951456312 0.8940347945025898 0.342085103264471 3.349932259027002 4.295622811850572 1.233599840087162 0.3264185554851845 0.0710216104257229 1.0 0.2747845331601694 0.0150894096676388 0.0761326596447121 +Ventricular hypertrophy 20 43 2.7184820734920723 0.0065582209415302 10.04126213592233 36.45873786407767 1.1361758135608295 0.3518404639351837 4.440080726024568 4.153106961798495 1.0569836433105884 0.3376234863759063 0.0018794247710073 1.0 0.0632956597671369 0.0276263990590475 0.0021166596662764 +Macular degeneration 5 15 2.713593176400348 0.0066557847706387 3.5072815533980584 13.201456310679612 0.7081764422831481 0.3007939344006393 1.5711122114355351 1.3240485924903622 1.388921785741595 0.3097317018961461 0.0371575218425068 0.0018407641855875 0.0135419734012732 0.0367529115341812 0.039409055534926 +Hyperlipidemia 14 33 2.7043604407473323 0.00684360103289 7.682038834951456 29.6626213592233 0.5392307404617857 0.3728005101645487 3.9693446328110418 2.956030683250849 1.27614168259521 0.3117729697341341 0.0530236274766455 1.0 0.1487873266068847 0.0285848308842562 0.0564249445308771 +Abnormal auditory evoked potentials 5 10 2.6954960595972297 0.0070283909080317 2.837378640776699 8.45388349514563 0.8113355275163785 0.2966376606156203 1.5470802196866602 1.3128600166506037 1.1722229382642326 0.2813987538538041 0.000257114308785 1.0 0.1758008751515455 0.01180448121602 0.000277756887713 +Impaired proprioception 17 45 2.690357284212968 0.0071375556978818 9.813106796116504 38.25485436893204 1.0894904790984437 0.3853358407663543 4.186376779745541 5.223695147901442 1.052731732437443 0.3596256989246241 0.0003758092929537 0.3503528550879276 0.2178091494673695 6.662600223935429e-05 0.0004305757320285 +Abnormal csf protein level 9 14 2.6767727411251494 0.00743350365846 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.0022588883215701 1.0 0.0538434207197609 0.0142235096743441 0.002448268499096 +Peripheral demyelination 10 17 2.673609822162204 0.0075039701725572 4.524271844660194 16.973300970873787 0.9472740181618832 0.3208012027704231 2.3341893675900383 2.269845761985369 1.1784704386991718 0.3026863353342601 0.0088126864345141 0.1644315705571846 0.005693097574516 0.0130060888805635 0.0094203676276074 +Polyneuropathy 7 22 2.656437004528392 0.0078971203913034 5.689320388349515 18.633495145631063 1.1475655107151586 0.297256939859202 2.871111980426299 2.8359934163787166 1.1251440285742276 0.3008764483611514 0.0030894736318666 0.2180755491779121 0.0135419734012732 0.0082403851981354 0.0033710493096369 +Decreased activity of mitochondrial complex iv 3 18 2.6132995263163323 0.0089672674834759 3.878640776699029 15.9247572815534 0.8034271187166634 0.3445303465767608 2.844656052218728 1.5238137800378977 1.1422119451186783 0.2970372577525856 0.0429593131307029 0.0075879492488378 0.0023694947377154 0.0043549454623746 0.0448872219881859 +Clumsiness 12 22 2.606173454096203 0.0091560081897679 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 0.0083585032956262 0.2068720246493716 0.0115248505447769 0.006410021202963 0.0090060858517451 +Postural tremor 8 21 2.6061129108870693 0.0091576268111934 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 9.000102347034974e-05 0.1723099894081314 0.0065760397653667 0.0003658042695641 0.0001003888941435 +Macroglossia 15 38 2.5919187064773768 0.0095442321555736 8.597087378640778 33.800970873786405 0.2378332400826553 0.526108686434358 3.4819634097071916 3.0993577519995683 1.045257905641647 0.335668429128709 0.1160404427828354 1.0 0.628446438408612 0.2342378017446612 0.1230798220666872 +Focal white matter lesions 5 10 2.5820257513328744 0.0098222255591255 2.1650485436893203 6.592233009708738 0.089443384386372 0.4887730102934108 1.54917508508414 1.469342982450118 0.9893169835592576 0.2930307336510276 0.0005000280862091 0.0683810764565047 0.1349531130589082 0.0051503840765812 0.0005338561483377 +Toe walking 12 26 2.573975381714312 0.0100537426547264 6.740291262135922 22.805825242718445 1.1386089770349623 0.3130572717722256 3.272869930973316 2.572476621751866 1.068544148592376 0.2998505070337083 0.0027258361045354 1.0 0.3896854720293997 0.3513790442708272 0.0029760556157756 +Progressive hearing impairment 4 14 2.561139845036808 0.0104329351173524 3.504854368932039 13.148058252427184 0.4932597459658353 0.5051973540320235 2.1230303786098608 1.7953340594318845 0.8479433956843728 0.303028922046226 0.0274491625860484 1.0 0.2941077913158182 0.0107757845080475 0.0289613396123399 +Oromandibular dystonia 4 7 2.554127850732661 0.0106454159922428 1.730582524271845 4.956310679611651 1.1882502597012077 0.2382412593757527 1.131086190944388 1.1979083634266432 0.9893427275402558 0.2482274576089271 0.0003469428870386 1.0 1.0 0.0041946485896371 0.0003706302782608 +Optic neuropathy 7 24 2.552784836017739 0.0106865490271084 6.834951456310679 22.009708737864077 0.7947386425872367 0.3403162177193031 3.144874354625535 3.3508299091739815 1.3090216253320466 0.3062511530983536 0.0018316295872898 0.0213334360876883 0.0011293669878184 0.0009951056419778 0.002003382390012 +Abnormality of the optic nerve 80 275 2.5494150677625496 0.0107903790352952 55.26699029126213 243.98300970873785 0.3330545875114519 0.7420961441999799 15.8565039079985 26.975306987282984 0.8419720138567378 0.3446258953426701 1.3821774827974582e-06 0.3687664287520152 0.0954071849649078 0.0010777609569759 4.688781212631816e-07 +Global brain atrophy 5 23 2.546119210722049 0.0108927982103272 4.944174757281553 20.466019417475728 0.5470181350831151 0.5081828354508747 2.583421763532785 2.0184370286085005 0.920761985531802 0.3339660659374047 0.0196376688878439 0.1916891885455893 0.0693457394610891 0.0230341265569123 0.0209086601360684 +Mucosal telangiectasiae 4 11 2.537965807577041 0.0111498877429532 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.0097790119883011 1.0 0.2372212797486779 0.0294507732567689 0.0103633783340074 +Impaired vibratory sensation 17 36 2.524136387945224 0.011598292077384 7.536407766990291 29.62621359223301 0.76301203268979 0.4693506811924163 3.6948054205684504 4.667704809367026 0.9514363452495296 0.3439929646326011 0.0029470982291359 0.2989716991852097 0.162236447621752 0.0021979061624995 0.0032642482875436 +Abnormal enchondral ossification 13 32 2.522437795231479 0.0116544560666449 8.825242718446601 28.097087378640776 0.9354465670440578 0.4238671948965085 3.7994051258084856 4.343870948544361 0.9586864854575652 0.3408490652683477 0.0007763344953891 1.0 1.0 0.1553404749607282 0.0008792700286468 +Ankle clonus 7 17 2.521284176530834 0.0116927379400759 3.575242718446602 13.298543689320388 0.6380030192173395 0.4332907678689981 2.0352878876827107 2.085711402355677 0.9658483329689804 0.311402478823635 0.0031187173192781 1.0 0.2590666885683055 0.0383377547470353 0.0033472823991884 +Resting tremor 9 22 2.509899787290397 0.0120765427982518 5.026699029126213 19.063106796116504 0.4260292617298505 0.4633026869029207 2.2429535349404746 2.4427221124580822 0.9815581137258528 0.3036505506177132 0.0001632705518591 1.0 0.3404254693467198 0.0036383017284534 0.0001817739981452 +Abnormal nervous system electrophysiology 36 206 2.495432189141939 0.0125803798182699 36.47572815533981 182.9004854368932 0.3300418821967583 0.7178291062368368 12.295191782751669 18.7740085709633 0.7539598524877194 0.3420878538095431 0.0029361940071974 0.6687234233039726 0.1796225356724959 0.0014150414812507 0.0037221665749688 +Limb ataxia 13 29 2.478886355709844 0.0131793290088793 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 0.0004428739671461 1.0 0.4353012614103685 0.0029289523616429 0.0004954067345962 +Corneal opacity 21 64 2.4642326807331014 0.0137306943068202 15.480582524271844 53.95631067961165 0.9517965339960472 0.3644495779961974 5.277458167452316 6.791845051563607 1.5225460520633525 0.3686110256368129 0.0001019439849853 0.2232696206807863 0.1086376771095568 0.0404257087798394 0.0001252823007649 +Macrovesicular hepatic steatosis 2 9 2.4549908759041283 0.014088816425313 2.466019417475728 6.87621359223301 0.939079379807938 0.3067324443022926 1.4701927354039712 1.258646689249585 1.014263353538022 0.2700508944960845 0.0102186935599103 1.0 1.0 0.0231366382468947 0.0106255777102749 +Increased cerebral lipofuscin 4 5 2.446258742822746 0.014434736769842 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 5.1265180635653765e-05 0.0461123069087121 9.839858993160587e-05 6.292953854873037e-05 5.489393781591606e-05 +Lacticaciduria 4 7 2.4418843943452737 0.0146108245399871 1.674757281553398 4.849514563106796 0.7129753583310345 0.3234768766519366 1.205184467740076 1.4436586333991552 1.2463576287305282 0.29112130721695 0.0005000280862091 0.0021914548918381 0.0003602808960722 0.0051503840765812 0.0005338561483377 +Abnormal glycosylation 10 23 2.4383085428700197 0.0147561730680911 6.043689320388349 21.259708737864077 0.4368319789530849 0.4886321385908432 2.9093144657736354 3.168109894482179 1.024724777664989 0.3264729071151926 0.004578910583524 0.1878492321971458 0.3467918934582977 0.2887846572413305 0.0049481295197396 +Stroke like episode 4 8 2.437461345633746 0.014790795466538 1.9320388349514563 5.347087378640777 0.7802983779647638 0.3377286829697849 1.3402806250303152 1.5433591727314462 1.1185957061594276 0.2970042406174105 0.0009513571658216 1.0 0.1515272625734178 0.0074273483269255 0.0010145405611514 +Abnormality of glycolipid metabolism 4 7 2.433684195572969 0.0149460287858229 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 5.1265180635653765e-05 0.0461123069087121 0.0039135152062846 0.0231366382468947 5.489393781591606e-05 +Areflexia of lower limbs 12 26 2.4271895033288717 0.0152163054662175 6.601941747572815 21.186893203883496 0.8014885285213843 0.4297204254543569 3.042066893889402 3.372723692373783 0.977277602505203 0.3249512351298445 0.0013774193602078 1.0 1.0 0.0007908116200209 0.0015084049643282 +Progressive neurologic deterioration 10 22 2.415786821280099 0.0157012509159819 6.75 20.466019417475728 0.5813429756502071 0.2930928839947513 2.6727908035631316 1.300228015706032 1.5791549964390388 0.3142214461904322 3.925397329585003e-06 1.0 0.3404254693467198 0.0036383017284534 4.502168619247678e-06 +Poor eye contact 11 42 2.411407727689615 0.0158910723179439 9.774271844660197 38.25970873786408 0.6634270903175611 0.4886810186458507 3.917228340019005 4.329065002822378 1.0573021214973186 0.3538640004920722 0.0001876964984568 0.0473022522201117 0.0055234944679999 0.000401529451794 0.0002142043583912 +Abnormal visual fixation 2 8 2.41035324420576 0.0159370815856843 2.1237864077669903 6.516990291262136 0.3282606812074232 0.2644845064785266 1.2333226229346623 1.2136771814929264 1.4687997702265556 0.2650474123539905 0.0523318189589597 0.0814971443263516 0.1596960736798767 0.0693365470158766 0.0541965943180989 +Central apnea 3 8 2.408535921084275 0.0160166500307281 2.6140776699029127 7.645631067961165 0.7865100475706397 0.3005269589284746 1.5309416715650457 0.8593604190958345 1.1613991531101726 0.2793709321885783 0.0258872131820397 1.0 0.2070995190727305 0.4452488918515388 0.0271057364081029 +Morphological abnormality of the corticospinal tract 7 17 2.398717652836977 0.0164525954310585 3.686893203883495 15.03883495145631 0.5616218245613079 0.5231151147988415 1.9487419537195845 1.7976377708768945 0.8440336488225383 0.3280840546625515 0.073146977469922 0.1993158438338612 0.3655284832956332 0.0265672828357611 0.0767262889545654 +Abnormal macrophage morphology 3 7 2.387867425347776 0.0169464537021106 2.9150485436893203 5.640776699029126 -0.1129741045260028 0.144980672561322 1.3090672390975422 1.117854819168669 1.9286041303300476 0.1913667515871486 0.0059987647490075 0.0727733471903131 0.1432798584585485 0.0561137872346343 0.00630824692371 +Microcornea 7 33 2.3673647641259623 0.0179152660790549 6.223300970873787 27.9004854368932 0.466347775811294 0.5952452592567805 3.105529171282791 3.8348554430650177 0.7011549915883155 0.306673764898096 0.1066830928487404 1.0 1.0 0.0952407027608542 0.1132746653755905 +Hyperintensity of cerebral white matter on mri 8 22 2.366390982246984 0.01796246356989 5.844660194174757 19.76456310679612 0.5239793769920946 0.3497882694217939 2.383223245915457 2.1845455756818453 1.3844482033830876 0.3203944687906004 0.0002355677663993 0.018891152845815 0.0008840144918394 0.0044406378118471 0.0002619380543045 +Abnormal circulating lipid concentration 30 82 2.360274720852525 0.0182614060009078 21.0995145631068 75.44417475728156 1.321442689138656 0.3287247628796158 8.33534407984455 6.5596064623065375 1.4065018349702674 0.365722219395451 2.632477501128695e-05 0.5610374568462058 0.0254451356639491 0.0002917097590196 3.26977595311029e-05 +Abnormal protein glycosylation 9 20 2.3553102241899966 0.0185072477055525 4.992718446601942 17.04854368932039 0.4349711267577257 0.4629072595890348 2.62316887373748 2.93994465563356 1.0108477090998502 0.3020677841214376 0.0013880477544212 0.1564797373419447 0.2941077913158182 0.2166326226637888 0.0015071148532441 +Hemiparesis 10 19 2.351359652276056 0.0187049445104146 4.492718446601942 16.453883495145632 0.5632847994166561 0.5250125610456521 2.3039529956499933 2.7457486053720115 0.80325121159606 0.3108877318797908 0.0239966669088923 1.0 0.4407605172427877 0.0148252690690975 0.0022883393024557 +Slurred speech 7 11 2.3503094529772235 0.0187578090371598 2.45873786407767 8.864077669902912 0.5323927403653204 0.4147809462031548 1.4075891250208603 1.616351781434359 0.9973486618272436 0.2852319096618858 0.0097790119883011 1.0 1.0 0.0294507732567689 0.0103633783340074 +Meningitis 5 8 2.3452646823337604 0.0190135765410968 2.179611650485437 6.274271844660194 0.789971069936712 0.3622376484019577 1.3480557177345056 1.3864875660317604 0.9776190102947984 0.2839276823170232 0.4253564839389538 1.0 1.0 0.5213399099817488 0.4325786085596129 +Left ventricular systolic dysfunction 7 9 2.338428014652925 0.0193650558804996 2.0024271844660193 6.274271844660194 0.8306323903703577 0.3188570764916028 1.4472920586220064 1.367095356040773 1.072243004538969 0.2702909744520516 0.0859119874297797 1.0 0.191600110602388 0.0983610682747182 0.0888008652079453 +Nasogastric tube feeding in infancy 2 8 2.335833755662284 0.0194999075882476 3.0097087378640777 8.495145631067961 1.0003947416243104 0.2675726652756056 1.510449978803449 1.1668877069106371 1.1016283190777107 0.2724768109071007 0.160353317011437 0.1280604643503683 0.031373049189738 0.1552222190730896 0.1652047572335966 +Dysostosis multiplex 5 9 2.325099343124975 0.0200666487741285 3.983009708737864 7.990291262135922 0.4150973501220912 0.1595724105588133 1.65382835361071 1.246316090990369 1.8479195153421644 0.2123242141003258 0.0003455086863903 1.0 0.1837383274168749 0.0135296171343662 0.0003730251283681 +Abnormal ldl cholesterol concentration 7 15 2.3190688032277955 0.0203913059889635 3.3907766990291264 12.616504854368932 0.1598459071865069 0.3035988995241804 1.922077248743316 1.8231306205769169 1.371220486686296 0.2515253044142337 0.1263793020712777 0.1155957163384056 0.0255840399150975 0.1300982938321277 0.1303826157459173 +Frequent falls 12 44 2.318702125347229 0.0204111932131851 8.643203883495145 38.75485436893204 0.6268988624161936 0.4831027569691007 4.0086529499315136 3.828305504664436 1.0909180744790496 0.3651237988976172 0.0007763344953891 0.061791584068653 0.0497306095082375 0.0047559214034701 0.0008792700286468 +Abnormal chorioretinal morphology 16 31 2.3181242721391846 0.0204425681285298 8.45631067961165 26.4004854368932 0.7945769566543296 0.4616483000942599 3.6317817687878136 4.493501214243663 0.9878512993647718 0.3399479614013815 0.0422704961666863 1.0 1.0 0.1355974813948723 0.0458044806843984 +External ophthalmoplegia 11 20 2.314436586412039 0.0206437859425761 5.0 17.00242718446602 0.5663831977441792 0.4827064568652057 2.377074975025652 3.293490775365303 0.8939003315322738 0.3080856115403083 0.0058905817960326 1.0 0.3593428278464597 0.0048857385669874 0.0063580922287898 +Abnormal pericardium morphology 7 13 2.312838501457271 0.0207315200782798 3.487864077669903 10.762135922330096 1.0304485268572945 0.2849705132346721 1.7172308655515107 1.695717994097398 1.0794817436655069 0.2735310781030822 0.2219477285215065 1.0 1.0 0.0484311287755044 0.228153712059568 +Abnormal choroid morphology 17 33 2.307597421809072 0.0210215380498597 8.601941747572816 27.3495145631068 0.7703870977149745 0.4720542672282273 3.667860427157979 4.9083023341259215 0.9853391072008848 0.3404582870775928 0.0838721172796442 1.0 1.0 0.1947645910993377 0.0901224775631308 +Decreased activity of mitochondrial complex i 8 38 2.302562527763036 0.0213034695459488 9.281553398058252 33.63834951456311 0.9162605947168436 0.3572379048008119 4.7041965890170365 4.116953486956332 1.2998989973013628 0.34388058367185 0.0006262846835991 0.0238997911322505 0.0001225386178253 0.0002096397492041 0.000693808475419 +Temporal pattern 4 8 2.300388579182381 0.0214262152842203 1.922330097087379 7.20873786407767 0.5136219769844315 0.3826897646309282 1.2536495878411025 1.3600119071520798 1.070617499374129 0.2689352766129853 0.0523318189589597 1.0 1.0 0.0087554356838108 0.0541965943180989 +Tissue ischemia 9 21 2.2979459574396364 0.0215648651598752 4.669902912621359 20.01941747572815 0.4670703905456849 0.5376214087969519 2.554791232762714 1.8952192409705757 0.8387891641382008 0.309595447618788 0.4666090710583638 1.0 0.5071521873221705 0.5313676216131358 0.4777080304114748 +Abnormal left ventricle morphology 13 33 2.287523217949466 0.022165301819905 8.155339805825243 27.79368932038835 0.5948246759118737 0.4756129570470222 3.598158324912058 3.3281177777105677 1.054918773522773 0.3428402347836221 0.0056472346784388 1.0 0.1862598674919939 0.1374400519295191 0.0062283989950113 +Personality changes 4 18 2.2789880556946667 0.0226677753339177 4.235436893203883 16.20873786407767 0.716641708966708 0.4361664780008399 2.2513009299259603 2.2727002372019856 0.9467269936740988 0.3182188186141179 0.0338215073326569 1.0 0.3076603852203092 0.0020925837152473 0.0356460972875996 +Loss of speech 6 22 2.271909128385132 0.0230919994485758 5.453883495145631 19.1626213592233 0.4726173662677797 0.3013153148889984 2.223071754411353 1.8941045281154043 1.521023928928509 0.3006842241053739 0.003500521827279 0.0165768393094286 0.0075361578498098 0.0182997950486615 0.0037872519575486 +Clonus 18 41 2.270699401177732 0.0231651813055047 8.04611650485437 31.93446601941747 0.5828978309354407 0.490454230151838 3.78619227044226 4.424455038167712 0.8696948910263331 0.3203390008180061 3.0784070406457244e-05 1.0 0.1862598674919939 0.0036501932708164 3.6005403560523816e-05 +Arteriosclerosis 8 18 2.259235270811545 0.023868753918822 4.885922330097087 14.944174757281552 0.0721468675738393 0.2032976413320727 1.852339343238996 2.0572604199467093 1.788928597657784 0.2405012300780825 0.026251582611606 0.2031027035797352 0.0775813155228076 0.1099245732268714 0.0279038521060528 +Disproportionate short limb short stature 13 24 2.258469852942581 0.0239163820328625 6.587378640776699 19.902912621359224 1.344701363676014 0.2682000023842777 2.8599402401133336 3.1206003999939886 0.9439707190715964 0.2973700803613334 0.0156047854966435 1.0 1.0 0.2274506769816413 0.0168669379700177 +Hypersplenism 3 10 2.246895633301265 0.0246466978588828 2.7184466019417477 7.970873786407767 0.2142260937784027 0.1548364087136437 1.1589036979530396 1.1444786041391362 1.8316571038254568 0.2005205006822401 0.0059987647490075 1.0 0.1432798584585485 0.0062267265321947 0.00630824692371 +Mitochondrial inheritance 2 5 2.246209467006856 0.024690594137918 1.577669902912621 4.247572815533981 0.9928856357718184 0.2727497270810077 1.119676794457053 1.2095369137272214 1.2442723588935711 0.2811589341958167 0.0324301480805536 0.0683810764565047 0.0088504827764808 0.0051503840765812 0.0336357980244025 +Proximal amyotrophy 8 17 2.2455812465042064 0.0247308428079573 4.718446601941747 13.856796116504857 0.6037658559324836 0.4972994712742096 2.2062025350790946 1.7602342703705265 0.8206757208003167 0.3130721595344946 0.0083546496185296 1.0 1.0 0.4846912912858679 0.0088588626715525 +Cogwheel rigidity 4 8 2.2421673679417444 0.0249505573100268 1.691747572815534 5.41747572815534 0.5245835815764137 0.3763230502268936 1.2788913032023987 1.4212279105346624 1.148580263275354 0.3055796210169491 0.0385296980798545 0.0727733471903131 0.1432798584585485 0.0561137872346343 0.039942155971048 +Psychomotor deterioration 7 10 2.2347405772141964 0.0254343850242804 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 1.5180285244009463e-05 0.0595353304203936 0.0066572828402184 0.0382400085743442 1.6468344784532795e-05 +Hypocholesterolemia 4 9 2.232169927746172 0.0256037341506212 3.2645631067961167 8.048543689320388 1.205673434171466 0.2055905154190861 1.747510449264718 1.0646904903887575 1.232151298114248 0.2464368010987078 0.0026425445039808 1.0 0.0066572828402184 0.0382400085743442 0.0027834726260547 +Schizophrenia 6 21 2.2277913437539767 0.0258944323648968 5.444174757281553 19.50242718446602 0.9817145874838714 0.3473822480141803 2.400301366302062 2.641618717487706 1.084663392230114 0.3211478296747099 0.0030399610577812 0.1762218760282218 0.0588586045542952 0.016869226769582 0.0032909138457879 +Abnormal retinal morphology 61 241 2.227656091059945 0.0259034571708798 45.478155339805824 213.00485436893203 0.2870296460039429 0.6766928177985854 13.550409605643804 22.682270903247453 0.9517483504445162 0.3613196633465952 0.0004025529992902 0.086237549535081 0.0500732252749923 0.0005751784121257 0.0005613133776296 +Cardiac conduction abnormality 14 34 2.2224156618511137 0.0262552278650596 7.54126213592233 30.07766990291262 0.9307918135366152 0.3911403090848463 3.486554807604548 3.5456504747498965 0.9289536354013204 0.3216072900435658 0.0202391625142957 0.3315322885250054 0.0483217377147592 0.0551022953292233 0.0219681008445407 +Progressive external ophthalmoplegia 6 12 2.2181463945689903 0.0265448523500009 3.378640776699029 10.228155339805824 0.6986896615619974 0.3934319655103426 1.8174798771838792 2.269764004486748 0.9524665755192452 0.2940766219203315 0.0083546496185296 1.0 0.2297987482657219 0.0038040834633598 0.0088588626715525 +Abnormal epiphyseal ossification 8 19 2.213632989608344 0.0268540360288775 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.0010175887234885 1.0 1.0 0.0901467992310857 0.0011157102419642 +Urinary glycosaminoglycan excretion 3 7 2.2025976086958505 0.0276231226180718 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 0.0046737877195888 1.0 1.0 0.0498779046475234 0.0049176108076387 +Pain 57 199 2.1985253472651927 0.0279116902981422 37.08009708737864 174.89563106796118 0.560521494187844 0.6082034136674831 12.418311408681989 15.731400802334642 0.9626712538875356 0.3834317739449847 0.0009385703663293 0.670979697467727 0.3196647622128578 0.0032621416190398 0.0003370717847298 +Supraventricular arrhythmia 8 20 2.1950841560097816 0.0281575615327405 4.172330097087379 16.20873786407767 0.0959401021368949 0.5881039757765105 2.5173015695396503 2.6749687157635855 0.8075275459374517 0.2939950412707787 0.1368116694516355 0.236404668572991 0.1039407380726692 0.1596086760652474 0.1427791401704325 +Abnormality of the musculature of the lower limbs 13 30 2.192630831574259 0.0283339878897004 6.565533980582524 25.90776699029126 0.508988513486999 0.5486864479414023 3.113247057195523 3.357535773447294 0.8220902923092538 0.3269446155121387 0.0214238557943388 0.2889042268874887 0.502334803954571 0.096818905200251 0.0231032125645871 +Capillary hemangioma 2 6 2.190003934446153 0.0285239514818258 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.2092417220825769 0.1444128696349771 0.2732850813359189 0.1899587232036964 0.2151867556135544 +Abnormality of lipoprotein cholesterol concentration 8 16 2.188144779657715 0.0286590579568883 3.594660194174758 13.79126213592233 0.146670453757452 0.3159030988618912 2.0804850608489107 1.8940687593815968 1.3545369944331518 0.2589389983473483 0.1722386963203812 0.1321770275159086 0.0334071197556988 0.1637924032376012 0.1773693871336699 +Rhizomelia 9 14 2.185092168191194 0.0288820893777024 4.276699029126213 11.868932038834952 1.3783619481702345 0.228956695884812 2.09278482575067 1.6655579622091714 0.936017394236602 0.2616202806826952 0.0679082749535201 1.0 1.0 0.3067990234802971 0.0712683628665124 +Cytochrome c oxidase negative muscle fibers 3 9 2.183623096480679 0.0289899549600838 2.128640776699029 7.565533980582524 0.5494269119427225 0.4045538407163497 1.5858767129346854 1.5274435957395311 1.011527854197758 0.3026481749587328 0.0451678162600437 0.0771453392642774 0.1515272625734178 0.062605312422627 0.0468003866103798 +Ascending tubular aorta aneurysm 3 6 2.183066074313027 0.0290309445013952 1.3907766990291262 4.655339805825243 0.9226580213396618 0.308376966533443 1.1148653010373335 0.8882434018008132 0.9888017972034884 0.2648823222498504 0.142942638307071 1.0 0.1265462710440741 0.290751966651369 0.1462762019757018 +Atrophy degeneration involving the caudate nucleus 2 6 2.1821272164528684 0.0291001450521506 1.2888349514563109 4.283980582524272 0.3751529128205025 0.4147621281846377 1.0481475114547032 1.0836094304135666 1.1513114797047737 0.3142236199023666 0.0174422350800748 0.0550816697898294 0.1094892401774078 0.00262770885776 0.0181181417645757 +Abnormal cardiac ventricular function 10 24 2.17514476740632 0.0296192696181076 5.262135922330097 18.648058252427184 0.6561483334031016 0.4063512942618581 2.801563935800768 3.037775296806565 1.0608023601658336 0.302693194134391 0.0286331132971941 1.0 0.0365585180593606 0.0368512438420236 0.0308069773506126 +Absent brainstem auditory responses 2 5 2.1689360390130883 0.0300875401780944 1.2621359223300972 3.29126213592233 0.6081713287168207 0.4585682937347684 0.8669908348643095 0.6443340501463214 0.969578489228779 0.3116706709719169 0.007414327658262 1.0 1.0 0.0188064524051028 0.00771353919978 +Abnormal full field electroretinogram 1 8 2.167608520761952 0.0301884849021862 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.3209583813715978 0.0056070915236824 0.0219975904219434 0.1139407547181512 0.3271248077551284 +Abnormal light and dark adapted electroretinogram 1 8 2.167608520761952 0.0301884849021862 1.7985436893203883 7.135922330097087 0.8897551200199579 0.2742817695009352 1.2050451450005106 0.7670210145007976 1.1859557261264115 0.267107203595487 0.2487525021118799 0.0039064712270754 0.0155240337321844 0.0834574734746242 0.2539261987860491 +Hepatic failure 18 53 2.166583449173789 0.0302666305243093 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 0.0003456808203675 0.0831018560335817 0.0166529196858764 0.0032728763104503 0.0003991294178904 +Unusual infection by anatomical site 7 15 2.1650921331912665 0.0303806303066849 3.907766990291262 13.49271844660194 0.7293808434681487 0.4605880442375236 1.9820157102817233 2.372464489866843 0.7897149485111757 0.3081613942392058 0.1872542329078324 1.0 1.0 0.3157753203157507 0.193832289989472 +Cns demyelination 5 16 2.163581957288481 0.0304964474955249 4.330097087378641 13.868932038834952 0.932085489476866 0.3543850979390085 1.8689509518649636 1.4505793369743718 0.9962875819434424 0.3044831103069028 0.0031187173192781 0.1362745587685063 0.0354914601129098 0.0063239101987386 0.0033472823991884 +Abnormality of the achilles tendon 8 14 2.1603878666241187 0.0307426559476948 4.514563106796117 12.898058252427184 0.5609866518495084 0.4955323823848279 2.2986449265697204 1.5070372517492898 0.9168070129914432 0.3209091792598189 0.0779463222258674 1.0 1.0 0.5661975770404395 0.0811948723624906 +Myoclonus 29 107 2.1581666592289497 0.030914876588461 19.92718446601942 92.40291262135922 0.7794869182612147 0.4142145469430702 6.660238401732631 11.33633180094438 1.369340457412049 0.3858779422292388 1.4058392165724656e-05 0.0318689399206328 0.000167874814449 4.9172971300694113e-05 6.707965280446294e-06 +Osteoarthritis 6 11 2.150467293383193 0.0315182703998093 3.783980582524272 10.466019417475728 1.011181157871384 0.2141266987491498 1.7388858389175554 1.4384831140913243 1.3548711699904423 0.2434324139099127 0.0429593131307029 1.0 0.2372212797486779 0.0043549454623746 0.0448872219881859 +Progressive spasticity 4 16 2.1490038993564453 0.0316340908438896 4.310679611650485 15.677184466019416 0.3665295652655519 0.4383580490709103 2.2099911092980777 1.5344471301085942 1.08331515350054 0.3117516214812866 0.0040771188388817 0.1029565435856987 0.0202898922491691 0.0020705519968491 0.0043329575683166 +Shoulder girdle muscle weakness 7 15 2.146650590668861 0.0318211090765498 4.004854368932039 12.42233009708738 0.8387402263996985 0.3756529644451753 2.0785487207705367 2.2836026739757753 0.9187113892871612 0.2934865228782298 0.004326259109494 1.0 0.2732850813359189 0.1899587232036964 0.0046379242911556 +Proximal tubulopathy 8 26 2.140189960502745 0.0323394181858334 7.269417475728155 23.25 0.6812729764745832 0.3939568357360496 3.269858916003623 2.8782959157530654 1.2124757185225692 0.3205652179980567 0.0001632705518591 0.1839914155878272 0.0007430351028178 0.0005468287448316 0.0001817739981452 +Orthostatic hypotension 7 14 2.139638983092053 0.0323839536371455 3.6262135922330097 14.315533980582524 0.2234754096973065 0.4106322335953559 1.878879089774009 1.367959097892007 1.1506876393484995 0.291561214686976 0.1487321052173485 1.0 0.2372212797486779 0.1467432355955838 0.1533018949933901 +Abnormality of the musculature of the thigh 5 9 2.135915964135881 0.0326862641300331 2.7135922330097086 7.885922330097087 0.5148289177149923 0.5016293543943551 1.4879808788630329 0.9724834956477112 0.8386175054598112 0.3078570403374032 0.1263621008341029 1.0 1.0 1.0 0.129364196063302 +Abnormality of skull ossification 7 15 2.134836349488966 0.0327743799956101 4.366504854368932 12.970873786407768 1.1881205011944458 0.2637442069575459 1.99249670608582 1.4511884027191762 0.8848235988748787 0.2626440236811827 0.000158928930674 1.0 0.2802926639431586 0.0484311287755044 0.0001753252601336 +Abnormal circulating long chain fatty acid concentration 3 6 2.133324847984587 0.0328980872341098 2.0728155339805827 4.861650485436893 1.0288291622755297 0.284696092465088 1.384567800831184 1.563474222630441 1.0358408470651057 0.2764983518284591 0.0075518132359909 1.0 1.0 0.0074273483269255 0.0079370796506279 +Mania 6 17 2.131525284645865 0.0330458916845259 4.29126213592233 13.815533980582524 0.5633198814967983 0.4160552944360035 2.179476502394243 2.2801276272213657 1.0919629859527038 0.3085705503430486 0.0005381299217597 1.0 0.2590666885683055 0.000812960139445 0.0005860509424053 +Abnormal thoracic spine morphology 7 28 2.124231087231577 0.0336508249321312 6.558252427184466 27.104368932038835 0.8238927765093872 0.4398474942511601 2.7009535990178555 2.5649391710658156 0.8855000478727516 0.3360788168488923 0.0091509880896993 0.0343104139968933 0.0216384292134882 0.0629955787418294 0.0099258782765325 +Diffuse cerebral atrophy 7 20 2.114641559712799 0.0344605086998808 4.320388349514563 16.526699029126213 0.5483679808262946 0.4347204443631116 2.152955035100649 2.40585163991881 0.9855175878314706 0.3059596216572743 0.0058477253853617 1.0 0.2872333566147377 0.2076979954646016 0.0012662122150735 +Atrophy degeneration involving the corticospinal tracts 6 15 2.114481481225803 0.0344741648185837 3.046116504854369 12.830097087378642 0.5862844965366169 0.5076242219583529 1.6751494545754666 1.7194679099903734 0.8501612708621024 0.329209288406221 0.0994577887656966 0.1604648724397155 0.3009165941166509 0.0596874537258691 0.1034478004905659 +Neuronal loss in central nervous system 4 15 2.108272467708842 0.0350074280373358 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0131101518098011 1.0 0.2518545844225215 0.1637924032376012 0.0138780941766985 +Mitochondrial respiratory chain defects 1 6 2.108130440261164 0.0350197080419367 1.8033980582524272 5.177184466019417 1.0048180638921334 0.285673153216041 1.1353491002390874 1.0681459460620504 1.0953831291184488 0.2879410254685434 0.1772895401336459 0.0727733471903131 0.0100519320580488 0.0561137872346343 0.1812716861639223 +Episodic vomiting 9 13 2.103856787044622 0.0353909414532762 4.179611650485437 11.12378640776699 1.060494846441687 0.2663322982599159 1.9809215871966128 1.7630834730718608 1.1982900451883365 0.2840581402107739 0.0150315815195717 0.1362745587685063 0.0354914601129098 0.0063239101987386 0.0159032502878613 +Abnormal muscle fiber morphology 34 80 2.103720364665889 0.035402846962619 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 8.304531067729727e-06 0.0398412828369274 0.0692932819421307 0.0005350287648629 1.0398149254383485e-05 +Flat face 9 27 2.1030539889480573 0.0354610503499901 6.66747572815534 24.08495145631068 0.4902055675682596 0.5473999825637093 3.284800305273881 3.633055728953568 0.8018127166907104 0.315636792407103 0.0120082692023945 1.0 1.0 0.5673549770689735 0.0130876591736213 +Progressive visual loss 5 26 2.098553013591132 0.0358563220005312 5.325242718446602 22.429611650485437 0.7316954387450431 0.34231947196034 2.467466703195611 2.985791083259841 1.255625436621734 0.3056268024259221 0.1433179209748266 0.0473022522201117 0.0055234944679999 0.0089239350034266 0.0267628454277298 +Biliary cirrhosis 2 7 2.097161709962001 0.0359792627608308 1.9733009708737863 6.650485436893204 1.1218722294682368 0.279893930524248 1.1603338056285764 0.598683634692072 0.8535321112514973 0.2502325498718601 0.0174422350800748 0.0550816697898294 0.1094892401774078 0.0328731354880699 0.0181181417645757 +Cerebral dysmyelination 2 8 2.090993922954712 0.0365286087417795 1.6286407766990292 7.055825242718447 0.5887869749232204 0.3891898742700928 1.2754040277752834 0.7202278823189237 0.9907764921844316 0.2830027899418403 0.0385296980798545 1.0 0.1432798584585485 0.0561137872346343 0.039942155971048 +Proximal upper limb amyotrophy 4 8 2.087521369077564 0.0368410314710416 2.4271844660194173 6.922330097087379 0.5481727902715954 0.4742953229469802 1.5832983990206078 1.0234087377162515 0.8608602495896207 0.3018374099681791 0.3251899972986247 1.0 1.0 1.0 0.3290745839784397 +Abnormality of the musculature of the upper arm 4 8 2.087521369077564 0.0368410314710416 2.4271844660194173 6.922330097087379 0.5481727902715954 0.4742953229469802 1.5832983990206078 1.0234087377162515 0.8608602495896207 0.3018374099681791 0.3884169954573494 1.0 1.0 1.0 0.3928150466925536 +Migraine 12 25 2.083187925870676 0.0372340972473295 5.716019417475728 23.116504854368937 0.5491247833805577 0.5283138672374208 2.829188308518868 3.093372090575774 0.8241882772707269 0.3182507609453459 0.0086063198722403 1.0 0.5119234098565739 0.002033856678576 0.0029540076202437 +Achilles tendon contracture 6 13 2.081652094878398 0.0373742593041734 4.004854368932039 11.279126213592232 0.5734466657319717 0.5136155316960331 2.137273403229174 1.1955626751800683 0.8553039294976645 0.3252433518045028 0.0533849032097689 1.0 1.0 0.5213399099817488 0.0557230881301947 +Airway obstruction 5 16 2.0713843870240325 0.038322888776936 4.116504854368932 15.12378640776699 0.9459797966632624 0.3434111484412289 1.9597947726604712 2.1010208413382245 1.0021021721123982 0.3085532788047633 0.0583054293713105 0.2400196775334175 0.107004894081217 0.0515621560092188 0.0616372597750657 +Generalized myoclonic seizure 11 44 2.066486432605243 0.0387825721774905 9.177184466019416 40.04854368932039 0.4529392195590967 0.4207459458757411 3.6022058822892773 4.354728800706526 1.2466313924241157 0.3493918392140687 0.0305261206967526 0.1108331437781347 0.0290362076287452 0.0090874501470917 0.0145791680587165 +Dyschromatopsia 3 8 2.0616327598514403 0.0392427126442764 1.9563106796116505 6.881067961165049 0.8116181676256156 0.3616454151850379 1.3027357251175682 1.008666728011197 0.9552278076961072 0.2951208666933738 0.0135568966381937 1.0 0.1008375048293403 0.0020064706347618 0.00138858926748 +Orthostatic hypotension due to autonomic dysfunction 4 9 2.0602143930131973 0.0393780495544462 2.8689320388349513 9.026699029126211 0.6690910568198125 0.3153802844238013 1.4405048418053912 0.8105887688186777 1.185865447592776 0.2910194211316744 0.0268788760081442 1.0 0.1265462710440741 0.0439142352380576 0.0278921605814954 +Abnormality of lower limb joint 47 188 2.05566655638016 0.039814667641465 33.80582524271845 166.25242718446603 0.2412979108610408 0.7714482514929651 11.09824463722585 17.08912584844864 0.6310491383229854 0.3006235946777967 0.0033733703157436 0.4014747485983234 0.3230841989063536 0.0473893103572098 0.0042649465356824 +Progressive spastic quadriplegia 4 8 2.055008789410081 0.039878155770904 2.6407766990291264 8.094660194174757 0.8041722661618813 0.2980182786117089 1.3079619433616207 1.0302561803519357 1.23715789109981 0.2930725496255146 0.0102186935599103 0.0461123069087121 0.0039135152062846 0.0231366382468947 0.0106255777102749 +Amelogenesis imperfecta 2 5 2.049813843597347 0.0403826001712983 0.8397932816537468 2.565891472868217 0.724536889189433 0.4035744021138592 0.7743751060130646 1.1997736300717985 1.2614985611497236 0.3306862689524208 0.0268788760081442 0.0639684350193291 0.1265462710440741 0.0439142352380576 0.0278921605814954 +Aspiration pneumonia 11 24 2.04731364717166 0.0406272987956186 6.315533980582524 24.78640776699029 0.083708145584179 0.5218050560615539 3.915670714200723 1.846805089231015 1.0748395775922797 0.3323493433966079 0.0711087454924313 0.2507644527164699 0.4461675288226883 0.0600215848699845 0.0278547210480151 +Inverted nipples 7 9 2.044238435626727 0.0409299978432082 2.825242718446602 7.560679611650485 0.5742526021095823 0.4293603144776698 1.7358425081015891 2.1819443374032397 1.0022452058355265 0.3096465985683321 0.7825740025256316 1.0 1.0 1.0 0.7873897147619485 +Bradykinesia 11 28 2.0428223610131075 0.0410700261557201 6.432038834951456 24.740291262135923 0.3209702495465398 0.647210353509448 2.8366092705608312 3.366457605313076 0.6755594138973282 0.2952553111098991 0.0636312299406509 1.0 1.0 0.1044322137967542 0.0676022626142099 +Bilateral sensorineural hearing impairment 11 28 2.042791429262566 0.0410730893609363 6.381067961165049 24.424757281553397 0.7447297270654177 0.4543730451773109 2.694462286764978 2.8252792093863337 0.8997615483176746 0.3241521581359238 0.1156615300782399 1.0 0.0949012099695084 0.1423397245441582 0.1208874805839759 +Foam cells 3 6 2.0377017162725517 0.0415797724529469 2.9611650485436893 5.398058252427185 -0.064606162326146 0.1366553329191208 1.1817572081322671 0.893230265545378 1.9405286208577948 0.1862104272675829 0.0003135208860554 0.0370595951599339 0.0743799864466655 0.0148625463558957 0.0003311660608568 +Myoclonic seizure 15 57 2.035688295401942 0.0417816651565103 11.686893203883496 52.98543689320388 0.3944988422537482 0.4078474078990697 4.250245345088794 5.776566450302065 1.383306240067707 0.3629970156021384 0.0045799557208282 0.1519896688943138 0.0529971691837449 0.0030240075518844 0.0020762810412892 +Decreased absent ankle reflexes 6 18 2.0335476050315737 0.041997229146794 4.54126213592233 13.740291262135925 0.614698131143983 0.4646843865398717 2.302541095049457 2.6371188884218366 0.9410514279256472 0.3107404522460847 0.0018025827173796 1.0 1.0 0.0043549454623746 0.0019380906235741 +3 methylglutaconic aciduria 4 12 2.031520892878957 0.0422021823295859 4.072815533980583 10.594660194174756 0.3579974396117663 0.4371570089867337 2.2174372584356252 1.5620718849823747 1.1566220028171512 0.333066618505644 0.0012658498659003 1.0 1.0 0.0693365470158766 0.0013491401517078 +Atlantoaxial abnormality 2 5 2.031071433205022 0.042247748827854 1.4660194174757282 3.849514563106796 1.0726212659562588 0.2746386395490074 0.9171032274068438 1.0957440869823794 1.0965015067037602 0.2693675199183011 0.0102186935599103 1.0 1.0 0.0231366382468947 0.0106255777102749 +Retinal telangiectasia 1 5 2.028476454546752 0.0425116440035484 1.3106796116504855 5.007281553398058 0.8088648966265131 0.3483026313211161 1.0430456357811864 1.087191709833904 1.1553193033520868 0.3106693264231038 0.2306946942738637 0.0858288536093336 0.014058804472369 0.0762921742488627 0.2355870590704462 +Parkinsonism 12 34 2.023912838829064 0.0429791206895262 7.453883495145631 30.097087378640776 0.7249761134976155 0.4663275088289313 3.116711838694066 3.708464636913605 0.8967824567735009 0.3291722600978801 0.0216827181147801 1.0 0.5657328567415809 0.1553404749607282 0.0235212982094472 +Fetal distress 7 26 2.023342396923919 0.0430378586177018 6.694174757281553 23.524271844660195 0.315106981366531 0.4342915849252123 3.1374136043562535 2.920781449478041 1.1333892319914325 0.2945358880670072 0.0004360179627124 0.1683799151698467 0.0061250241039257 0.0142235096743441 0.000479523089417 +Limb girdle muscular dystrophy 4 9 2.017188550127477 0.0436758404956563 2.7888349514563107 8.21359223300971 0.4599246853103626 0.5270635431045678 1.712765209268149 0.9744352154278332 0.8013904434340989 0.3018684920930001 0.5218077647813364 1.0 1.0 1.0 0.5269580067311792 +Abnormal speech prosody 2 9 2.0120688863160643 0.0442126759364167 1.7184466019417477 7.531553398058253 0.8238611105871386 0.3292070194756458 1.3593793253030109 1.1305443806694235 1.0768574157850217 0.2870822069632543 0.0451678162600437 0.0771453392642774 0.0113213926532688 0.0074273483269255 0.0468003866103798 +Very long chain fatty acid accumulation 2 7 2.0111032664638 0.0443145502387662 2.1820388349514563 5.470873786407767 0.5842375287416242 0.4040997577361238 1.517972497559233 1.851692013853064 1.0678239713607651 0.3118623380771133 0.0451678162600437 1.0 1.0 0.062605312422627 0.0468003866103798 +Increased ldl cholesterol concentration 5 11 2.010814220701599 0.0443450834854777 2.466019417475728 9.092233009708735 -0.2239097220499274 0.320127491790266 1.5379694972203586 1.5316207115206113 1.3088687012404925 0.2512376917026361 0.2127275138623692 0.0814971443263516 0.1596960736798767 0.357118555081159 0.2173267675800807 +Hyperlipoproteinemia 5 11 2.010814220701599 0.0443450834854777 2.4902912621359223 9.300970873786408 -0.2334402023779523 0.3281082864585681 1.5602473393108425 1.5443913650600527 1.2897346825889175 0.2523514437001098 0.2487525021118799 0.0901405579438761 0.1758008751515455 0.3879443652654283 0.2539261987860491 +Progressive gait ataxia 8 14 2.0038363414767635 0.0450875945073137 3.3810679611650487 11.0873786407767 0.9190295749650902 0.2658532875386696 1.7592835107251577 1.880439920211323 1.2434873962438642 0.2734996669217905 0.0040771188388817 0.1029565435856987 0.0013262573806951 0.0173886328284286 0.0043329575683166 +Hand polydactyly 13 37 2.002315004255125 0.0452508632939385 9.114077669902912 32.17718446601942 0.810453590544338 0.4452800586149166 3.6615419153480793 5.309376559579211 0.948384387998628 0.3474317696921568 0.0477989293003274 0.5003808284845332 0.7583477142273662 0.2797613861439376 0.0522066704240287 +Centrally nucleated skeletal muscle fibers 6 9 2.000069597286412 0.0454927491698611 2.6432038834951457 7.385922330097087 0.337303529113138 0.4859248811978309 1.512529363330304 1.4121854830820135 0.9597116029085156 0.3025094388096049 0.0768164760449794 1.0 1.0 0.4028006685093745 0.0794376465838621 +Slow decrease in visual acuity 3 9 1.998986140719708 0.0456098534333155 2.313106796116505 7.985436893203883 0.7332483742783148 0.3617245659278226 1.567733834853386 1.5547551717475598 1.083959755774155 0.2999488674407273 0.3388072419805803 0.1114021565620111 0.0237627189197599 0.1219531221716571 0.031065887399213 +Periventricular white matter hyperintensities 3 9 1.997193008398781 0.0458042202815613 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 0.0046737877195888 0.0683810764565047 0.0088504827764808 0.0051503840765812 0.0049176108076387 +Ovoid vertebral bodies 2 8 1.9971156784984565 0.0458126181389622 2.6237864077669903 7.359223300970874 0.2693483252678329 0.2925663833748981 1.3659227234427256 1.183251804829311 1.455225024558189 0.2873440473038876 0.0768164760449794 1.0 1.0 0.090818300458346 0.0794376465838621 +Abnormality of alkaline phosphatase level 11 27 1.989963171283848 0.0465949926196151 5.424757281553398 21.550970873786408 0.2837846270756372 0.4096308965627429 3.0903339262997473 2.8582743162812116 1.1598915940568888 0.2934678757183479 0.0962196654305933 0.2143583684675494 0.3896854720293997 0.1257511849434855 0.1007202116491234 +Barrel shaped chest 3 6 1.9894789518142824 0.0466483627897582 1.674757281553398 4.473300970873787 1.1869997902874323 0.2609030887925388 1.0385967424919742 0.917344085691108 0.8975397916941404 0.2534223349008651 0.00356078515082 1.0 1.0 0.290751966651369 0.0037486095651754 +Postaxial foot polydactyly 3 11 1.98620991752833 0.047010020100568 2.9101941747572817 8.179611650485437 1.1164564935210708 0.2854713626620553 1.5514456024758956 2.174827712105029 0.9565986562813577 0.2724819159224514 0.1872542329078324 1.0 1.0 0.3157753203157507 0.193832289989472 +Abnormality of the 5th toe 3 11 1.98620991752833 0.047010020100568 2.9223300970873787 8.259708737864077 1.1073405288994291 0.2882520454965396 1.560677724258624 2.165041741031587 0.9522253135241228 0.2721172964763348 0.3025606390512588 1.0 1.0 0.4120011086653588 0.3116472395700642 +Abnormality of coordination 83 343 1.9676170401259048 0.0491121176014885 65.05339805825243 312.07766990291265 0.3537206479527984 0.7134221988982268 20.398983010696288 29.808593053234937 0.9921840157004412 0.3756105558441653 2.8172979952914465e-08 0.0813616654315639 0.0847687907529706 2.2116921543356303e-05 1.0398889640182588e-08 +Coxa valga 12 25 1.966071922695289 0.0492903031685763 5.245145631067961 19.95145631067961 0.3761170106319844 0.4485543113651226 2.6522752145550523 3.395824508532713 1.0354006500412785 0.2987185055269495 0.0328286673975903 1.0 0.4620800234731917 0.0191561107000251 0.0350702895254342 +Abnormal peripheral myelination 14 38 1.9643287454553409 0.0494919801993403 7.635922330097087 32.13592233009709 0.6742900044491671 0.4743014543601314 3.568806451618386 4.873244854452022 0.9969709958674222 0.3457305187498817 0.0188662968516844 0.3283440482523609 0.0469329673676288 0.0528572065128901 0.0204898881061494 +Abnormal arterial physiology 11 30 1.964320378172248 0.0494929499196268 6.218446601941747 26.953883495145632 0.6799967252485163 0.4871419269266132 2.869465887610158 2.4604264895945303 0.8630108658008876 0.3264277839815205 0.2708712030141581 1.0 0.5863803216648996 0.1788573615140471 0.2816515364833329 +Abnormal circulating citrulline concentration 2 5 1.963534460158852 0.0495841044083475 1.519417475728155 4.283980582524272 0.9322911204120568 0.2795135602214257 1.0297099461920487 1.0355035731992424 1.235992875942202 0.2843671782204088 0.0174422350800748 0.0550816697898294 0.0056684159955205 0.00262770885776 0.0181181417645757 +Progressive psychomotor deterioration 6 8 1.960525934417538 0.0499343497640947 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0001486934237484 1.0 0.1094892401774078 0.0328731354880699 0.0001590313802548 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5e2dda81167e5fdfedc21fc74352c3e3694950a4 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 4655, + "title": "Average number of proteins per term", + "value": 25.912567132116003 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7e78b6998d1116939ec62a872a9f78445726ff92 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f14abafee37fea4f47b5ef9efda337206696e9c7 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1782 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cognitive impairment 0.4382718408661822 4.63414793664027 3.5841062908659183e-06 0.0165456368125724 0.0166840147839855 183 Q9Y2R0,P33897,Q9BQE5,O75381,P36543,P35637,P13473,Q9NZJ7,Q7LG56,P50897,P00846,Q9NZ08,O76024,P05067,P06280,Q5XKP0,Q9H9S5,P16278,Q9H2C2,P07196,P17900,O95470,P04062,P54802,Q13510,P00403,Q9BRK0,P21912,P06865,Q9NPL8,Q06787,Q9NQZ5,O75503,O15118,P07602,P27544,P21964,Q6DKK2,P03886,Q96RL7,O60313,Q9Y487,P42345,O60220,P12235,Q9Y619,Q10713,Q99720,Q969G3,O00429,Q14108,P40855,Q13217,Q9H6K4,Q9Y287 55 +Muscle abnormality related to mitochondrial dysfunction 0.5660163120431649 3.297128231275752 0.0009767889389262 0.989424070525356 0.3204893734284946 40 Q9Y2R0,Q96CU9,Q86Y39,Q53H12,P03886,Q7LG56,P00403,O60313,P00846,Q9UBX3,Q9NPL8,O43676,O96000,P12235 14 +Sensorimotor neuropathy 0.5601812139521262 3.252750477214712 0.0011429381370515 0.9951239498266136 0.3204893734284946 39 P07196,Q9Y2R0,P33897,Q5KU26,Q9NZJ7,Q7LG56,P00403,P03886,O60313,O00429,Q9NR77,P00846,P07602 13 +Abnormal retinal artery morphology 0.6288229619902808 3.2057973391788477 0.0013468881213167 0.998115306998688 0.3204893734284946 24 P17900,P21964,Q9NZJ7,P03886,Q13510,P00846,P07602,P16278,P10619 9 +Abnormal circulating cholesterol concentration 0.5689723164666547 3.196672603861024 0.0013902262245422 0.9984600505310424 0.3204893734284946 35 Q8WXH0,Q8N511,O75845,P61916,Q13045,P50402,Q9NZJ7,Q9BTV4,P07602,P02545,Q15125,Q15392,Q15904,Q14739,Q15800,Q9NVI7,P37268 17 +Hepatomegaly 0.3516626288379414 3.1899166236656873 0.0014231384518605 0.9986790814457872 0.3204893734284946 189 P23786,O75381,Q86Y39,P09601,Q9NZJ7,Q9UJW0,P00846,O43676,P00374,Q9NVI7,Q9HC07,P16278,Q86WC4,Q96A33,P04062,P54802,Q13510,Q16134,Q9NPL8,O15118,Q01844,P07602,Q96CU9,O75845,P10253,O00754,Q9HC21,P03886,Q96I36,Q96RL7,Q9BT22,Q9BUB7,Q9UP83,Q9NWS8,O96000,Q9Y619,P08236,Q16625,Q96HY6,Q15904,Q14108,Q14739,P40855,P15586,Q96AA3 45 +Abnormal biliary tract morphology 0.6080504880630093 3.164255341704057 0.0015548032211594 0.9992850095430572 0.3204893734284946 25 P09601,Q9NZJ7,P04062,Q14739,Q14108,Q5XKP0,P07602 7 +Biliary tract abnormality 0.5926722273017839 3.130705631927178 0.0017438686400572 0.9997038945353964 0.3204893734284946 28 P09601,Q9NZJ7,P04062,Q9UJW0,P07602,O96028,Q14739,Q14108,Q5XKP0,O95202 10 +Dementia 0.558172772345584 3.0994509464497377 0.0019387967981161 0.9998806988198428 0.3204893734284946 65 P33897,P35637,Q9NZJ7,Q7LG56,P00846,O76024,P05067,P17900,P04062,P00403,Q13510,P21912,P06865,Q06787,O15118,Q9NQZ5,P07602,P27544,P03886,Q96RL7,O60313,Q9Y487,O60220,O00429,Q14108,Q9Y287 26 +Scotoma 0.7336302238042396 3.034396356236014 0.0024101755320942 0.999986768486503 0.3204893734284946 14 P03886,O60313,P04439,P00846,Q9H6K4,Q9H061,O60220,Q9Y287 8 +Bulbar signs 0.7563231277422842 3.0058711016406585 0.0026482123096904 0.9999956432317398 0.3204893734284946 13 P35637,Q9NZJ7,P03886,Q99720,P04062,P00846,P07602 7 +Abnormal cellular phenotype 0.3463800308061586 3.0012203034658147 0.0026889994407801 0.9999963984711554 0.3204893734284946 203 P23786,Q9Y2R0,O75880,Q86Y39,P35637,P09601,Q9NZJ7,Q7LG56,Q9UJW0,P00846,O43676,Q9Y584,Q9P0J1,Q13510,P04062,P00403,P21912,Q16134,Q9NPL8,Q06787,Q96RD7,O14773,O75503,P07602,Q96CU9,Q16836,P21964,O00754,P03886,P13073,Q9UBX3,Q9BUB7,P42345,O96000,O60220,P12235,O75844,Q969G3,O00429,Q70HW3,Q9P0J0,Q15904,Q14108,Q7KZN9,Q14739,P15586 46 +Muscle stiffness 0.5777972654390225 2.9515559540552587 0.0031617725474146 0.999999603808412 0.3204893734284946 26 P23786,P33897,Q13586,Q9NZJ7,Q9BRK0,Q9NW15,P07602,P00846,Q15392 9 +Central scotoma 0.803413354658159 2.931891174258937 0.0033690478112453 0.9999998495139272 0.3204893734284946 11 P03886,O60313,P00846,Q9H6K4,Q9H061,O60220 6 +Optic atrophy 0.3442462778827221 2.9178224962293053 0.0035248494085788 0.9999999273171444 0.3204893734284946 210 O75381,Q86Y39,Q5KU26,Q9NZJ7,P50897,P00846,O76024,O95721,P06280,Q5XKP0,Q9NVI7,Q86WC4,P16278,Q9BPX6,Q9H2C2,Q9H9S5,Q9UGJ1,P00403,O43292,Q6ZXV5,P07602,O95202,Q53FT3,P51812,Q96CU9,O75312,P21964,Q96PU5,P03886,O60313,Q15125,O43505,P98175,Q96J42,Q9H061,O60220,Q6P4Q7,Q5H8A4,Q9P0J0,O96028,Q7KZN9,P40855,Q9H6K4 43 +Abnormality of corneal stroma 0.6885331807367242 2.914159075016961 0.0035664812152813 0.9999999401632576 0.3204893734284946 16 Q16625,P04062,Q13510,O43505,P16278,P10619 6 +Abnormality of head blood vessel 0.5669716253773152 2.8911498770957107 0.0038383501948424 0.9999999832002032 0.3204893734284946 27 P17900,P21964,Q9NZJ7,P03886,Q13510,P00846,P07602,P16278,P10619 9 +Abnormal tissue metabolite concentration 0.6700425994026865 2.880067830935514 0.0039758962110512 0.9999999911662588 0.3204893734284946 17 P33897,P17900,Q9NZJ7,P06865,P40855,P06280,P07602 7 +Left ventricular hypertrophy 0.5611406382056786 2.8718870746678 0.0040802874388896 0.9999999945768756 0.3204893734284946 28 Q6NUK1,O75880,O75208,P10253,P03886,Q7LG56,P00403,O75787,P21912,Q07021,P06280,Q9H9S5,P12235 13 +Mitochondrial myopathy 0.5400057444104593 2.8589051061997117 0.0042510593024776 0.9999999975590098 0.3204893734284946 33 Q96CU9,Q86Y39,Q53H12,P03886,Q7LG56,P00403,O60313,P00846,Q9NPL8,O43676,O96000,P12235 12 +Ventricular arrhythmia 0.521961639246168 2.843916360933299 0.0044562744012519 0.9999999990648512 0.3204893734284946 45 Q8WXH0,P23786,P50402,P10253,Q9BTV4,P13473,P03886,Q7LG56,P00403,P02545,Q99758,P21912,P00846,Q9HD47,P09493,P42892,P12235 17 +Cherry red spot of the macula 0.820472071933369 2.825495758794603 0.004720751295193 0.9999999997285196 0.3204893734284946 9 P17900,Q9NZJ7,Q13510,P07602,P16278,P10619 6 +Ventricular preexcitation 0.8352363393984643 2.825313177782559 0.0047234423881867 0.999999999731915 0.3204893734284946 8 P10253,P03886,P00846,P00403 4 +Mental deterioration 0.5135298128635958 2.821771164871412 0.0047759242467648 0.999999999790267 0.3204893734284946 105 P33897,Q9BQE5,P36543,P35637,Q9NZJ7,Q7LG56,P50897,P00846,O76024,P05067,Q5XKP0,P16278,Q9H2C2,P17900,O95470,P04062,P54802,Q13510,P00403,P21912,P06865,Q9NPL8,Q06787,Q9NQZ5,O75503,O15118,P07602,P27544,P21964,P03886,Q96RL7,O60313,Q9Y487,O60220,Q10713,O00429,Q14108,Q9Y287 38 +Ragged red muscle fibers 0.6041324577076743 2.813413811998006 0.0049018524764876 0.9999999998836284 0.3204893734284946 22 P03886,P00403,Q9H2D1,Q70HW3,P00846,P12235 6 +Disproportionate short stature 0.5487005603010321 2.797463144438327 0.0051505643053189 0.9999999999636504 0.3204893734284946 29 Q8WTW3,O15228,Q9Y366,Q96HY6,Q03164,Q32P28,Q15643,Q9UHX1,Q15125,Q14739,Q7LGA3,Q7RTS9,P42345,Q15392,P16278,P10644 16 +Elevated pulmonary artery pressure 0.5477448531378408 2.7893474919525443 0.0052814364121946 0.9999999999802968 0.3204893734284946 29 Q6NUK1,Q8WTW3,O75844,P20674,P04062,P03886,P00403,P02545,P01889,Q8IZA0,O14678,P22413,Q14108,P51970,O96000 15 +Horizontal nystagmus 0.5546338824132172 2.789256840013736 0.0052829150668947 0.9999999999804328 0.3204893734284946 27 O15020,Q9NZJ7,P04062,Q9NW15,O00429,O60313,Q9H061,Q5HYK3,P00846,O14773,P07602 11 +Progressive sensorineural hearing impairment 0.7717847276322345 2.766113397125295 0.005672880451621 0.9999999999968464 0.3204893734284946 11 P03886,P00403,O60220,O60313 4 +Morphological abnormality of the pyramidal tract 0.5840956191902298 2.759089393285749 0.0057962676947749 0.9999999999982302 0.3204893734284946 23 Q9Y619,Q9Y4P3,P33897,P35637,Q13045,Q9UBB4,O75569,P00846,O00400,Q12768 10 +Delusions 0.6087243698397494 2.7564435648479506 0.0058433695364539 0.9999999999985804 0.3204893734284946 21 Q9BQE5,P21964,Q9NZJ7,P04062,Q96RL7,P07602,O60220 7 +Abnormality of pulmonary circulation 0.5204540519677424 2.7216257651742963 0.0064961661515925 0.9999999999999332 0.3204893734284946 34 Q6NUK1,Q8WTW3,O75844,P20674,P04062,P49327,P00403,P03886,P02545,P01889,Q8IZA0,Q9NZ08,O14678,P22413,Q14108,P51970,O96000 17 +Ventricular hypertrophy 0.5071676173482651 2.7184820734920723 0.0065582209415302 0.9999999999999502 0.3204893734284946 43 P23786,O75880,P36543,Q7LG56,P02545,O75787,P06280,Q9H9S5,P00403,P21912,P22413,Q07021,O75208,P10253,P03886,Q96RR1,P12235,Q6NUK1,Q8WTW3,O75844 20 +Macular degeneration 0.6686379201740404 2.7135931764003476 0.0066557847706387 0.9999999999999684 0.3204893734284946 15 P51648,P04062,Q9NW15,Q13510,P50897 5 +Hyperlipidemia 0.5226942646905147 2.7043604407473323 0.00684360103289 0.9999999999999868 0.3204893734284946 33 Q8WXH0,P23786,P22830,O75844,O43707,O95470,P50402,Q13045,Q9BTV4,P28070,P02545,P50416,P06280,P49257 14 +Abnormal auditory evoked potentials 0.7894452516049475 2.6954960595972297 0.0070283909080317 0.9999999999999944 0.3204893734284946 10 P07196,Q9NZJ7,O60313,P07602,O60220 5 +Impaired proprioception 0.50610006242689 2.690357284212968 0.0071375556978818 0.9999999999999968 0.3204893734284946 45 P07196,Q9Y619,P33897,O14773,O15020,Q9BRK0,P54802,Q96RL7,Q9H6K4,P20700,Q9NR77,P00846,Q06787,O00400,Q13217,Q8N0X7,Q8IV08 17 +Abnormal csf protein level 0.673879809635785 2.6767727411251494 0.00743350365846 0.9999999999999992 0.3204893734284946 14 Q16625,Q9NZJ7,P03886,O43681,Q7LG56,P20700,P00403,Q9NR77,P07602 9 +Peripheral demyelination 0.6383862955023565 2.6736098221622036 0.0075039701725572 0.9999999999999994 0.3204893734284946 17 P07196,Q8TB36,P50570,P03886,Q9NZJ7,O43681,P20700,Q9NR77,P00846,P07602 10 +Polyneuropathy 0.5831390061566714 2.656437004528392 0.0078971203913034 1.0 0.3204893734284946 22 P33897,Q9NZJ7,P03886,O60313,P00846,O95721,P07602 7 +Decreased activity of mitochondrial complex iv 0.620418804277504 2.6132995263163323 0.0089672674834759 1.0 0.3211922068912761 18 Q9Y2R0,Q9Y584,P13073 3 +Clumsiness 0.5764925267794734 2.606173454096203 0.0091560081897679 1.0 0.3211922068912761 22 Q05086,O43819,O75503,O00754,Q9NZJ7,O43681,Q13510,Q15067,Q9NR77,Q96RR1,O14773,P07602 12 +Postural tremor 0.5881851423120114 2.6061129108870693 0.0091576268111934 1.0 0.3211922068912761 21 P35637,Q9BRK0,P03886,Q9NR77,P00846,Q14108,O14773,Q9H6K4 8 +Macroglossia 0.4889619002527118 2.5919187064773768 0.0095442321555736 1.0 0.3211922068912761 38 Q9Y4P3,P61978,Q9C0B1,Q05086,Q10713,P10253,O00754,Q96A33,P35250,P21912,P07686,Q7LGA3,O94905,Q9H9S5,P16278 15 +Focal white matter lesions 0.7673266588531028 2.5820257513328744 0.0098222255591255 1.0 0.3242727657995011 10 O00584,Q7LG56,Q9P0J1,P42345,P12235 5 +Toe walking 0.5319497995044931 2.573975381714312 0.0100537426547264 1.0 0.3289278789182406 26 Q8WXH0,Q8TD16,P35637,P50402,Q9BTV4,Q9NZJ7,O43681,Q99720,P02545,Q9NP80,P07602,Q9H9S5 12 +Progressive hearing impairment 0.6550841513484608 2.561139845036808 0.0104329351173524 1.0 0.3289278789182406 14 P03886,P00403,O60220,O60313 4 +Oromandibular dystonia 0.8244103893649165 2.5541278507326615 0.0106454159922428 1.0 0.3303355237112733 7 Q99720,Q96RL7,O60220,P35637 4 +Optic neuropathy 0.545083219239353 2.552784836017739 0.0106865490271084 1.0 0.3303355237112733 24 Q96CU9,Q86Y39,P03886,Q9P0J0,P00846,Q9NPL8,O43676 7 +Abnormality of the optic nerve 0.3421398085444622 2.5494150677625496 0.0107903790352952 1.0 0.3303355237112733 275 Q9UHX1,P50897,P00846,O43676,Q96TA2,Q9H490,P37268,Q6ZXV5,P07602,Q53FT3,Q96CU9,P49902,P03886,Q9UG56,Q9H061,Q9BSJ2,Q15067,P01889,Q9P0J0,O15460,Q7KZN9,Q7LGA3,Q9H6K4,Q12768,Q86Y39,Q04837,Q9NZ08,P51572,Q5XKP0,P16278,Q9H2C2,P04062,P49327,Q15058,P00403,Q15051,P51812,P21964,Q96PU5,O43681,O60313,Q96RR1,O43505,Q9Y6M9,Q96J42,O60220,P40855,Q9Y287,Q5KU26,Q9NZJ7,O76024,P06280,Q9NVI7,Q86WC4,P38435,P07196,O43292,Q9NPL8,O95202,P30153,O75312,Q15125,P98175,O96000,Q6P4Q7,Q5H8A4,O96028,O75381,P04439,O95721,Q9BPX6,Q9H9S5,Q9UGJ1,Q15043,O00754,Q9HC21,Q10713,Q969G3,O00429,Q96S66 80 +Global brain atrophy 0.5566570395622341 2.546119210722049 0.0108927982103272 1.0 0.3303355237112733 23 P33897,P35637,Q9UHX1,P07602,O60220 5 +Mucosal telangiectasiae 0.7292521603322453 2.5379658075770415 0.0111498877429532 1.0 0.3333590808964193 11 P06280,Q8IZA0,Q14739,P10619 4 +Impaired vibratory sensation 0.4907822081932101 2.524136387945224 0.011598292077384 1.0 0.3333590808964193 36 P07196,Q9Y619,P33897,O14773,O43819,O15020,Q9BRK0,Q96RL7,P20700,Q9NR77,Q96RR1,P00846,Q06787,O94905,O00400,Q12768,Q8N0X7 17 +Abnormal enchondral ossification 0.5064080993646414 2.522437795231479 0.0116544560666449 1.0 0.3333590808964193 32 Q9Y619,P08236,O75381,Q96HY6,Q15643,Q15125,P22413,Q14739,P40855,Q7RTS9,O96028,O95202,P38435 13 +Ankle clonus 0.6154998972984888 2.521284176530834 0.0116927379400759 1.0 0.3333590808964193 17 P33897,Q9NZJ7,Q9NW15,Q15043,O75787,P07602,O60220 7 +Resting tremor 0.5638621165858949 2.509899787290397 0.0120765427982518 1.0 0.3333590808964193 22 Q9NZJ7,Q7LG56,P04062,P07602,Q96RL7,Q06787,Q9H6K4,Q9BPX6,P12235 9 +Abnormal nervous system electrophysiology 0.3234475352401191 2.495432189141939 0.0125803798182699 1.0 0.3385067517574958 206 P33897,Q9BQE5,O75381,Q13045,Q9NZJ7,Q7LG56,P50897,O95721,Q9H2C2,P07196,Q96A33,P00403,Q9NR77,O43292,Q9NQZ5,O75503,O14773,P07602,O95202,P21964,P03886,Q96RL7,O60313,Q15125,P13073,Q9UBX3,O60220,Q9Y619,Q96N66,Q99720,Q5H8A4,Q14108,P40855,P51797,O15269,O96028 36 +Limb ataxia 0.5117928663567112 2.478886355709844 0.0131793290088793 1.0 0.3505701516361895 29 P07196,P33897,Q10713,O00754,O15020,P04062,Q9NW15,Q9UBB4,Q9NR77,Q14108,O14773,Q12768,Q8IV08 13 +Corneal opacity 0.495047500227914 2.4642326807331014 0.0137306943068202 1.0 0.3521674523414803 64 O75381,Q06136,P06280,Q9NVI7,Q9H9S5,P16278,P51648,P04062,Q13510,O95202,O75845,O00754,O43505,Q96J42,P10619,Q6NUK1,O75844,Q16625,Q5H8A4,P40855,O96028 21 +Macrovesicular hepatic steatosis 0.7472600619707263 2.4549908759041283 0.014088816425313 1.0 0.3521674523414803 9 P23786,Q5XKP0 2 +Increased cerebral lipofuscin 0.9257900677200844 2.446258742822746 0.014434736769842 1.0 0.3521674523414803 5 O75503,O14773,P50897,P07602 4 +Lacticaciduria 0.8007478865400579 2.4418843943452737 0.0146108245399871 1.0 0.3521674523414803 7 Q9BQT8,P03886,Q9P0J1,P00846 4 +Abnormal glycosylation 0.5430035852458661 2.4383085428700193 0.0147561730680911 1.0 0.3521674523414803 23 Q8N511,P36543,P51571,O75787,Q9BT22,Q15904,P46977,Q9UP83,Q9Y487,Q96AA3 10 +Stroke like episode 0.7569165398976099 2.437461345633746 0.014790795466538 1.0 0.3521674523414803 8 Q13586,P03886,P00403,O76024 4 +Abnormality of glycolipid metabolism 0.7990312347636013 2.433684195572969 0.0149460287858229 1.0 0.3521674523414803 7 P06280,Q9NZJ7,P07602,P17900 4 +Areflexia of lower limbs 0.5146171968582525 2.4271895033288713 0.0152163054662175 1.0 0.3521674523414803 26 P07196,Q13586,Q7LG56,Q96RL7,Q15067,O60313,O75787,Q9NR77,Q96RR1,Q13217,Q9H6K4,P12235 12 +Progressive neurologic deterioration 0.5516398380858665 2.415786821280099 0.0157012509159819 1.0 0.3521674523414803 22 P04062,Q9NZJ7,Q7LG56,P54802,P21912,Q9NPL8,Q9Y287,Q5XKP0,P07602,P16278 10 +Poor eye contact 0.4749592905200717 2.411407727689615 0.0158910723179439 1.0 0.3521674523414803 42 Q96CU9,O75746,Q86Y39,Q5KU26,P03886,Q9UHX1,Q9P0J0,Q9NPL8,O43676,Q5XKP0,O96000 11 +Abnormal visual fixation 0.7515744745083531 2.4103532442057594 0.0159370815856843 1.0 0.3521674523414803 8 P04062,Q13510 2 +Central apnea 0.7512169378031254 2.408535921084275 0.0160166500307281 1.0 0.3521674523414803 8 Q9NZJ7,P07602,O76024 3 +Morphological abnormality of the corticospinal tract 0.5973639283840806 2.398717652836977 0.0164525954310585 1.0 0.3521674523414803 17 Q9Y4P3,P33897,P35637,Q13045,P00846,O00400,Q12768 7 +Abnormal macrophage morphology 0.7894695930528758 2.3878674253477756 0.0169464537021106 1.0 0.3537477218983192 7 Q86WC4,Q13510,P16278 3 +Microcornea 0.4858929261071274 2.3673647641259623 0.0179152660790549 1.0 0.3657118880548737 33 Q13045,Q8NCH0,Q15125,O43505,Q96J42,Q9NWM8,Q9H9S5 7 +Hyperintensity of cerebral white matter on mri 0.5452731598487007 2.366390982246984 0.01796246356989 1.0 0.3657118880548737 22 P17900,P10253,Q9NZJ7,Q9P0J1,Q15043,O75503,P07602,Q96AA3 8 +Abnormal circulating lipid concentration 0.486595882535584 2.360274720852525 0.0182614060009078 1.0 0.3686889306828763 82 Q8WXH0,P23786,P33897,O75880,O43707,O75381,Q13045,Q9NZJ7,P28070,P06280,Q15392,Q9NVI7,P37268,Q8N511,Q9Y4P3,O95470,P07602,P22830,Q16836,P50402,O75845,Q15125,P50416,P49257,Q15800,O75844,Q03252,Q15904,Q14739,P40855 30 +Abnormal protein glycosylation 0.5650057772177164 2.3553102241899966 0.0185072477055525 1.0 0.3697478028727347 20 Q8N511,P36543,P51571,O75787,Q9BT22,Q15904,Q9UP83,Q9Y487,Q96AA3 9 +Hemiparesis 0.5738563165082236 2.3513596522760554 0.0187049445104146 1.0 0.3703271916268019 19 P33897,P03886,Q969G3,P00403,O00429,O60313,P01889,Q9NZ08,Q9NP80,P42345 10 +Slurred speech 0.6950958958446453 2.3503094529772235 0.0187578090371598 1.0 0.3703271916268019 11 P33897,O15020,Q9NW15,Q96RL7,O75787,Q9Y487,P16278 7 +Meningitis 0.7388152249132716 2.3452646823337604 0.0190135765410968 1.0 0.3703271916268019 8 Q8TAA9,P49327,P01889,O15460,Q9NZ08 5 +Left ventricular systolic dysfunction 0.7248726627510163 2.338428014652925 0.0193650558804996 1.0 0.3709643420729457 9 O75844,Q7LG56,P02545,Q96RR1,Q969Y2,P22413,P12235 7 +Nasogastric tube feeding in infancy 0.7369743055332786 2.335833755662284 0.0194999075882476 1.0 0.3720166796036581 8 P07602,Q9UHX1 2 +Dysostosis multiplex 0.7223315278637429 2.325099343124975 0.0200666487741285 1.0 0.3799418345054827 9 O00754,P54802,P15586,P16278,P10619 5 +Abnormal ldl cholesterol concentration 0.6067674892871419 2.3190688032277955 0.0203913059889635 1.0 0.3799418345054827 15 Q8N511,Q8WXH0,P50402,Q9BTV4,P02545,Q15800,P37268 7 +Frequent falls 0.4677301823233155 2.3187021253472295 0.0204111932131851 1.0 0.3799418345054827 44 Q13586,P04062,Q9NZJ7,Q7LG56,Q13510,Q9NR77,P21912,P00846,Q7RTS9,P07602,Q9H9S5,P12235 12 +Abnormal chorioretinal morphology 0.4874022560511952 2.3181242721391846 0.0204425681285298 1.0 0.3799418345054827 31 Q9Y619,O75381,Q10713,P52732,Q01082,O60826,P04439,O43505,Q9NX14,P40855,Q96J42,P53701,Q5XKP0,Q12768,Q9H9S5,Q9UGJ1 16 +External ophthalmoplegia 0.5594831119661692 2.314436586412039 0.0206437859425761 1.0 0.3799418345054827 20 Q8N183,Q13586,P50570,P03886,Q7LG56,P00403,O60313,P21912,Q96RR1,Q07021,P12235 11 +Abnormal pericardium morphology 0.6380879010468098 2.312838501457271 0.0207315200782798 1.0 0.3799418345054827 13 P04062,P02545,P01889,O15460,Q9NZ08,Q14108,P22413 7 +Abnormal choroid morphology 0.479496008892933 2.3075974218090716 0.0210215380498597 1.0 0.3831021397196807 33 Q9Y619,O75381,Q10713,P52732,Q01082,O60826,P04439,P22413,O43505,P40855,Q96J42,Q9NX14,P53701,Q5XKP0,Q12768,Q9H9S5,Q9UGJ1 17 +Decreased activity of mitochondrial complex i 0.4596780740006338 2.302562527763036 0.0213034695459488 1.0 0.3834875448603612 38 Q96CU9,Q86Y39,Q9Y584,P03886,Q70HW3,Q9UBX3,Q9NPL8,O43676 8 +Temporal pattern 0.7300728790607083 2.300388579182381 0.0214262152842203 1.0 0.383611662107869 8 Q9NR77,P04062,P21953,O60313 4 +Tissue ischemia 0.5471069977985029 2.2979459574396364 0.0215648651598752 1.0 0.3846147406866632 21 O75844,Q9Y4P3,P02545,P01889,O15460,Q9NZ08,P22413,P05067,P06280 9 +Abnormal left ventricle morphology 0.4773559057357941 2.287523217949466 0.022165301819905 1.0 0.3878927818483385 33 Q6NUK1,O75880,O75208,P10253,P03886,Q7LG56,P00403,O75787,P21912,Q07021,P06280,Q9H9S5,P12235 13 +Personality changes 0.5722206080345964 2.2789880556946667 0.0226677753339177 1.0 0.3922620601464202 18 Q96RL7,P03886,P04062,P00403 4 +Loss of speech 0.5331856827781227 2.2719091283851314 0.0230919994485758 1.0 0.393554448821622 22 P33897,P17900,Q9NZJ7,P50897,O15118,P07602 6 +Clonus 0.4598867393679288 2.270699401177732 0.0231651813055047 1.0 0.393554448821622 41 Q9Y619,P33897,Q86WC4,P35637,Q8N0X7,Q9NZJ7,Q9NW15,Q9BQT8,Q15043,Q99720,P20700,O75787,O75027,O60220,O00400,P07602,Q9H9S5,Q53FT3 18 +Abnormal circulating ceruloplasmin concentration 0.9410615963512992 2.2650433882303584 0.0235100170963893 1.0 0.3979604712134267 4 Q8N511 1 +Arteriosclerosis 0.5694265592815789 2.259235270811545 0.023868753918822 1.0 0.4019160951731947 18 O75844,O75845,Q13510,P02545,P22413,O15118,P16278,P38435 8 +Disproportionate short limb short stature 0.5092151993294337 2.258469852942581 0.0239163820328625 1.0 0.4019160951731947 24 Q8WTW3,O15228,Q9Y366,Q03164,Q15643,Q32P28,Q15125,Q14739,Q7LGA3,Q7RTS9,P42345,Q15392,P10644 13 +Hypersplenism 0.7036601094253462 2.246895633301265 0.0246466978588828 1.0 0.4046858685650691 10 P04062,Q14108,P07602 3 +Mitochondrial inheritance 0.8781695714198734 2.2462094670068553 0.024690594137918 1.0 0.4046858685650691 5 P03886,P00846 2 +Proximal amyotrophy 0.5750409437444082 2.2455812465042064 0.0247308428079573 1.0 0.4046858685650691 17 Q8WXH0,P07196,P35637,P50402,O14979,Q13586,P02545,Q9H9S5 8 +Cogwheel rigidity 0.7187960250521465 2.2421673679417444 0.0249505573100268 1.0 0.4046858685650691 8 O75787,Q7LG56,P00846,P12235 4 +Psychomotor deterioration 0.7013955163933021 2.2347405772141964 0.0254343850242804 1.0 0.4111009107223102 10 P36543,Q9NZJ7,Q7LG56,P50897,P06865,Q9Y487,P07602 7 +Hypocholesterolemia 0.7047190522621966 2.2321699277461717 0.0256037341506212 1.0 0.4124061677202139 9 Q15800,Q9NZJ7,Q9NVI7,P07602 4 +Schizophrenia 0.537939127701329 2.2277913437539767 0.0258944323648968 1.0 0.4143662994173388 21 Q9BQE5,P21964,Q9NZJ7,P04062,O76024,P07602 6 +Abnormal retinal morphology 0.3199932156412706 2.227656091059945 0.0259034571708798 1.0 0.4143662994173388 241 O75381,P36543,Q96S66,Q13045,Q9NZJ7,Q7LG56,Q9UHX1,P50897,P04439,P00846,Q9NZ08,O76024,Q5XKP0,Q9H9S5,P16278,P38435,Q9H2C2,Q9UGJ1,Q9Y4P3,P51648,P17900,P04062,Q13510,P00403,P21912,P22413,P06865,Q86YV9,O14773,O75503,P07602,O95202,P51812,Q96CU9,O75312,Q16836,P21964,O00754,P03886,Q8NCH0,Q9NW15,O60313,O43505,Q9UG56,Q96J42,Q9Y487,P10619,Q8WTW3,Q9Y619,Q10713,Q6P4Q7,Q5JRA6,Q5H8A4,Q15067,P01889,Q9P0J0,Q7KZN9,Q7LGA3,P40855,O96028,Q9Y287 61 +Cardiac conduction abnormality 0.466972239477564 2.2224156618511137 0.0262552278650596 1.0 0.4171265723954012 34 Q8WXH0,P23786,P36543,P50402,P03886,Q7LG56,P00403,Q07954,P02545,P21912,P00846,Q9HD47,P06280,Q9H490 14 +Progressive external ophthalmoplegia 0.6438326242522112 2.2181463945689903 0.0265448523500009 1.0 0.4202934955416813 12 P03886,Q7LG56,P00403,O60313,Q07021,P12235 6 +Abnormal epiphyseal ossification 0.5548413449688523 2.213632989608344 0.0268540360288775 1.0 0.420894066378536 19 P08236,O75381,Q96HY6,Q15125,Q14739,P40855,Q7RTS9,P38435 8 +Urinary glycosaminoglycan excretion 0.7513071232521993 2.2025976086958505 0.0276231226180718 1.0 0.4240987576416576 7 P54802,P15586,P16278 3 +Pain 0.3080297276609069 2.1985253472651927 0.0279116902981422 1.0 0.4240987576416576 199 Q8WXH0,P23786,P33897,O43707,P35637,Q9NZJ7,Q7LG56,Q8N1F7,P28070,P02545,P00846,Q9NZ08,P06280,Q9H9S5,Q9Y4P3,Q92804,P04062,P49327,Q13510,Q07954,Q9BRK0,Q15043,Q9NR77,P21912,P22413,Q06787,Q01844,P07602,Q15165,P21964,Q9BTV4,P50402,Q96D53,Q13423,O75569,O60313,Q96RR1,Q15800,P42892,P12235,O75844,Q03252,Q96HY6,Q8TAA9,Q13586,Q969G3,O00429,Q70HW3,P20700,P01889,O15460,Q14108,Q14739,O15269,Q9H6K4,P46020,Q8NFH4 57 +Supraventricular arrhythmia 0.5434894967269636 2.1950841560097816 0.0281575615327405 1.0 0.4240987576416576 20 Q8WXH0,P50402,Q9BTV4,Q7LG56,P02545,P00846,Q9HD47,P12235 8 +Centrocecal scotoma 0.9232052021316672 2.1926319875864952 0.0283339045334136 1.0 0.4240987576416576 4 P03886,P00846 2 +Abnormality of the musculature of the lower limbs 0.4767650713287255 2.192630831574259 0.0283339878897004 1.0 0.4240987576416576 30 Q8WXH0,P07196,P33897,Q12768,P50402,Q9BTV4,O14979,Q9NW15,Q96RL7,P02545,Q9NR77,P00846,Q9H9S5 13 +Capillary hemangioma 0.8100768956723488 2.190003934446153 0.0285239514818258 1.0 0.4242390771455115 6 Q7LGA3,Q9UHX1 2 +Abnormality of lipoprotein cholesterol concentration 0.5770455745926376 2.188144779657715 0.0286590579568883 1.0 0.4242390771455115 16 Q8N511,Q8WXH0,P50402,Q9BTV4,Q9UJS0,P02545,Q15800,P37268 8 +Rhizomelia 0.5956165005801526 2.185092168191194 0.0288820893777024 1.0 0.4242390771455115 14 Q8WTW3,O15228,Q9Y366,Q03164,Q15125,Q15392,Q14739,P42345,Q7RTS9 9 +Cytochrome c oxidase negative muscle fibers 0.6955896603739262 2.183623096480679 0.0289899549600838 1.0 0.4242390771455115 9 Q9Y2R0,Q7LG56,P12235 3 +Ascending tubular aorta aneurysm 0.808547361767497 2.183066074313027 0.0290309445013952 1.0 0.4242390771455115 6 O75844,P01889,Q06787 3 +Atrophy degeneration involving the caudate nucleus 0.8083404671118791 2.1821272164528684 0.0291001450521506 1.0 0.4242390771455115 6 P00846,Q96RL7 2 +Abnormal cardiac ventricular function 0.4992542212008243 2.1751447674063193 0.0296192696181076 1.0 0.4242390771455115 24 O75844,P10253,P03886,Q7LG56,P00403,P02545,P21912,P22413,Q9H9S5,P12235 10 +Absent brainstem auditory responses 0.8600487585073163 2.1689360390130883 0.0300875401780944 1.0 0.4256530667391539 5 O60220,O60313 2 +Abnormal full field electroretinogram 0.7044600583665115 2.167608520761952 0.0301884849021862 1.0 0.4256530667391539 8 P50897 1 +Abnormal light and dark adapted electroretinogram 0.7044600583665115 2.167608520761952 0.0301884849021862 1.0 0.4256530667391539 8 P50897 1 +Hepatic failure 0.4605696356025173 2.166583449173789 0.0302666305243093 1.0 0.4256530667391539 53 P22830,P23786,Q16822,Q16836,O75381,Q9Y619,Q10713,O75845,P04062,P03886,Q13510,P01889,P50416,O15460,P00846,P40855,O15118,Q86WC4 18 +Unusual infection by anatomical site 0.5833387269755458 2.1650921331912665 0.0303806303066849 1.0 0.4259693797518623 15 Q8TAA9,P49327,P01889,O15460,Q9NZ08,Q14739,Q9BUB7 7 +Cns demyelination 0.5734262854596928 2.163581957288481 0.0304964474955249 1.0 0.4263091984734792 16 P33897,P51648,Q9NZJ7,P40855,P07602 5 +Abnormality of the achilles tendon 0.5917939884107389 2.1603878666241187 0.0307426559476948 1.0 0.4284642617859869 14 Q8WXH0,Q8TD16,P50402,Q9BTV4,P02545,O60313,Q8N2K0,Q9H9S5 8 +Myoclonus 0.4563087594972 2.1581666592289497 0.030914876588461 1.0 0.429578359759063 107 P33897,O14653,Q9NZJ7,P50897,P00846,P05067,P00374,Q9H2C2,Q01105,P04062,Q13510,P00403,Q9NPL8,Q9NQZ5,O75503,O14773,P07602,P27544,Q96CU9,O75845,P03886,P13073,Q9UBX3,Q9NWS8,Q03252,Q10713,Q5HYK3,Q14108,Q96AA3 29 +Osteoarthritis 0.6594962207533395 2.150467293383193 0.0315182703998093 1.0 0.4311283053146754 11 O75844,Q96HY6,P04062,P02545,P01889,Q14108 6 +Progressive spasticity 0.5712825733317493 2.1490038993564453 0.0316340908438896 1.0 0.4311283053146754 16 P51812,O60313,P07602,P17900 4 +Shoulder girdle muscle weakness 0.5805580860372715 2.146650590668861 0.0318211090765498 1.0 0.4318579088960342 15 Q8TD16,O14979,Q9NZJ7,Q7LG56,P07602,Q9H9S5,P12235 7 +Proximal tubulopathy 0.4814691210774665 2.140189960502745 0.0323394181858334 1.0 0.4369487077707606 26 Q96CU9,Q86Y39,P03886,P00403,Q9NPL8,O43676,Q16134,O96000 8 +Orthostatic hypotension 0.5885911113446041 2.1396389830920532 0.0323839536371455 1.0 0.4369487077707606 14 Q04656,Q9NZJ7,P04062,O43681,P20700,P07686,P07602 7 +Abnormality of the musculature of the thigh 0.6866647839598089 2.135915964135881 0.0326862641300331 1.0 0.4375445602136604 9 Q8WXH0,P07196,P50402,O14979,P02545 5 +Abnormality of skull ossification 0.578779501493164 2.134836349488966 0.0327743799956101 1.0 0.4375445602136604 15 O75844,Q9HC21,Q15643,P54802,Q32P28,Q14739,Q86WC4 7 +Abnormal circulating long chain fatty acid concentration 0.7976145281149302 2.133324847984587 0.0328980872341098 1.0 0.4375445602136604 6 P23786,P33897,P40855 3 +Mania 0.5586472990313183 2.131525284645865 0.0330458916845259 1.0 0.4382581931380868 17 P51812,P21964,P03886,Q7LG56,P00403,P12235 6 +Abnormal thoracic spine morphology 0.47475357983568 2.124231087231577 0.0336508249321312 1.0 0.4450130399405422 28 O75844,P51648,O75845,O00754,P04062,Q9UHX1,Q7RTS9 7 +Diffuse cerebral atrophy 0.5328182153819533 2.114641559712799 0.0344605086998808 1.0 0.4510350301268853 20 Q10713,Q9NZJ7,O00429,Q06787,Q9UP83,P07602,P16278 7 +Atrophy degeneration involving the corticospinal tracts 0.5757202212553253 2.114481481225803 0.0344741648185837 1.0 0.4510350301268853 15 Q9Y4P3,P33897,P35637,P00846,O00400,Q12768 6 +Neuronal loss in central nervous system 0.5747882909297087 2.108272467708842 0.0350074280373358 1.0 0.4510350301268853 15 Q9NZJ7,P07602,P04062,P35637 4 +Mitochondrial respiratory chain defects 0.7920989098407298 2.1081304402611636 0.0350197080419367 1.0 0.4510350301268853 6 P00846 1 +Mixed demyelinating and axonal polyneuropathy 0.9021822689510202 2.1067015787880092 0.0351434552765963 1.0 0.4510350301268853 4 P03886,P00403 2 +Episodic vomiting 0.6042005885419066 2.103856787044622 0.0353909414532762 1.0 0.4510350301268853 13 Q9Y619,Q2TAA5,P61978,P03886,P00403,P22695,P00846,P49748,Q9NP80 9 +Abnormal muscle fiber morphology 0.4637854491365666 2.1037203646658895 0.035402846962619 1.0 0.4510350301268853 80 Q8WXH0,P23786,P35637,P50570,Q7LG56,P02545,P00846,Q5JTV8,O43676,P05067,Q9BPX6,Q9H9S5,P07196,P00403,Q9H2D1,O96008,P51114,P61978,P50402,Q9BTV4,O14979,Q9Y276,P03886,Q96RL7,O60313,Q96RR1,Q8NI60,Q9H173,P12235,Q13586,Q99720,Q5HYK3,Q70HW3,P51797 34 +Flat face 0.4748927648120962 2.1030539889480573 0.0354610503499901 1.0 0.4510350301268853 27 P08236,Q9NX62,O75381,O00754,Q15643,Q15125,Q9BUB7,Q9Y487,P40855 9 +Progressive visual loss 0.4767373414218581 2.0985530135911317 0.0358563220005312 1.0 0.4510350301268853 26 O14773,P03886,P50897,P00846,O75503 5 +Biliary cirrhosis 0.7299342579305161 2.097161709962001 0.0359792627608308 1.0 0.4510350301268853 7 P09601,Q14739 2 +Cerebral dysmyelination 0.6898485923060408 2.090993922954712 0.0365286087417795 1.0 0.4510350301268853 8 P33897,P07602 2 +Proximal upper limb amyotrophy 0.6891891391088371 2.0875213690775634 0.0368410314710416 1.0 0.4510350301268853 8 Q8WXH0,O14979,P02545,P50402 4 +Abnormality of the musculature of the upper arm 0.6891891391088371 2.0875213690775634 0.0368410314710416 1.0 0.4510350301268853 8 Q8WXH0,O14979,P02545,P50402 4 +Migraine 0.4771895730909041 2.0831879258706754 0.0372340972473295 1.0 0.4510350301268853 25 Q13586,P03886,P49327,Q7LG56,P00403,O60313,O00429,P01889,Q9NZ08,P05067,Q9NQZ5,P12235 12 +Achilles tendon contracture 0.6006434838094943 2.081652094878398 0.0373742593041734 1.0 0.4510350301268853 13 Q8WXH0,Q8TD16,P50402,P02545,O60313,Q9H9S5 6 +Airway obstruction 0.5599220812101309 2.0713843870240325 0.038322888776936 1.0 0.4609639463995792 16 O75844,Q96HY6,P21964,P09601,P06280 5 +Generalized myoclonic seizure 0.4430464567817456 2.066486432605243 0.0387825721774905 1.0 0.4629048038108172 44 Q9Y619,Q96N66,Q01105,P04062,Q9NZJ7,Q13510,P03886,P21912,P00846,P07602,P16278 11 +Dyschromatopsia 0.6842803330190305 2.0616327598514403 0.0392427126442764 1.0 0.4671990469542378 8 Q9H6K4,Q9H061,O60313 3 +Orthostatic hypotension due to autonomic dysfunction 0.6725952888387868 2.0602143930131973 0.0393780495544462 1.0 0.4676143384590491 9 Q9NZJ7,P07602,P04062,P20700 4 +Abnormality of lower limb joint 0.2985726020195279 2.0556665563801597 0.039814667641465 1.0 0.4711492769379651 188 P23786,P33897,P36543,Q8TD16,Q9NZJ7,Q9UHX1,O75787,Q5JTV8,Q9H9S5,P16278,P37268,Q9Y4P3,Q96A33,Q9Y584,Q13510,Q15043,Q9NR77,P21912,P22413,Q6ZXV5,P07602,O95202,Q9NX62,O75312,P49902,P21964,O00754,Q96PU5,Q9NW15,Q15643,Q15125,Q9UP83,Q9Y487,Q7RTS9,Q8N0X7,O60220,O75844,Q8WTW3,Q9Y619,P16435,P08236,Q03252,Q96HY6,Q5JRA6,Q7LGA3,Q96AY3,O96028 47 +Progressive spastic quadriplegia 0.6830264723653143 2.055008789410081 0.039878155770904 1.0 0.4711492769379651 8 Q9NZJ7,P07602,O43681,P17900 4 +Hypoplastic hippocampus 0.8887558405471059 2.051444209639843 0.0402237074708504 1.0 0.4740287551311618 4 Q86WC4,Q96RL7 2 +Amelogenesis imperfecta 0.832396466083268 2.049813843597347 0.0403826001712983 1.0 0.4746995045388733 5 Q13586,Q9HC07 2 +Aspiration pneumonia 0.4841291626895989 2.04731364717166 0.0406272987956186 1.0 0.4757012087416299 24 Q6NUK1,Q8TAQ2,P04062,Q969G3,Q13510,Q8N3U4,P20700,P78318,O95721,O60220,P16278 11 +Inverted nipples 0.6696402648497639 2.044238435626727 0.0409299978432082 1.0 0.4757012087416299 9 Q9H3H5,Q2TAA5,P61978,Q15067,P56589,P83436,Q96AA3 7 +Bradykinesia 0.4657318339393261 2.0428223610131075 0.0410700261557201 1.0 0.4757012087416299 28 Q96IX5,Q6DKK2,P04062,Q7LG56,Q96RL7,Q15043,O75569,O75787,Q96RR1,Q06787,P12235 11 +Bilateral sensorineural hearing impairment 0.4657284190427322 2.042791429262566 0.0410730893609363 1.0 0.4757012087416299 28 P35637,Q9NZJ7,O43681,P00403,P03886,Q15067,Q01082,Q96RR1,P38159,Q13217,P07602 11 +Foam cells 0.7767570281847732 2.0377017162725513 0.0415797724529469 1.0 0.4757012087416299 6 O15118,Q13510,P16278 3 +Myoclonic seizure 0.450844879348993 2.035688295401942 0.0417816651565103 1.0 0.4757012087416299 57 Q9Y619,Q96N66,Q01105,Q9UPT5,Q9NZJ7,P04062,Q13510,P03886,O43292,P21912,P00846,O75503,Q5XKP0,P07602,P16278 15 +Decreased absent ankle reflexes 0.5379006649641339 2.0335476050315737 0.041997229146794 1.0 0.4757012087416299 18 P07196,Q7LG56,Q96RL7,O60313,Q9H6K4,P12235 6 +3 methylglutaconic aciduria 0.6125868273108096 2.0315208928789574 0.0422021823295859 1.0 0.4757012087416299 12 Q9H6K4,Q5XKP0,Q9NVI7,Q9BUB7 4 +Atlantoaxial abnormality 0.8280757559221903 2.031071433205022 0.042247748827854 1.0 0.4757012087416299 5 Q9NWM8,Q8NCH0 2 +Retinal telangiectasia 0.8274781591935763 2.028476454546752 0.0425116440035484 1.0 0.4757012087416299 5 P00846 1 +Parkinsonism 0.4464222882280284 2.023912838829064 0.0429791206895262 1.0 0.4770029330128618 34 P35637,Q9NZJ7,P04062,Q96RL7,Q15043,O75569,Q99720,O75787,Q96RR1,Q06787,P05067,P07602 12 +Fetal distress 0.4682370438304855 2.023342396923919 0.0430378586177018 1.0 0.4770029330128618 26 Q96CU9,Q86Y39,P03886,Q9NPL8,O43676,Q9NVI7,Q86WC4 7 +Limb girdle muscular dystrophy 0.6646479759966991 2.017188550127477 0.0436758404956563 1.0 0.4829240795897391 9 Q8WXH0,O14979,P02545,P50402 4 +Abnormal speech prosody 0.6637046477305042 2.0120688863160643 0.0442126759364167 1.0 0.4834341068498801 9 P03886,P00846 2 +Elevated circulating long chain fatty acid concentration 0.8791503343671201 2.01173491432746 0.0442478880851056 1.0 0.4834341068498801 4 P23786,P33897 2 +Very long chain fatty acid accumulation 0.7126652413329311 2.0111032664637993 0.0443145502387662 1.0 0.4834341068498801 7 P33897,P40855 2 +Increased ldl cholesterol concentration 0.6350626343444037 2.010814220701599 0.0443450834854777 1.0 0.4834341068498801 11 Q8N511,Q8WXH0,P50402,Q9BTV4,P02545 5 +Hyperlipoproteinemia 0.6350626343444037 2.010814220701599 0.0443450834854777 1.0 0.4834341068498801 11 Q8N511,Q8WXH0,P50402,Q9BTV4,P02545 5 +Progressive gait ataxia 0.5677950070564586 2.0038363414767635 0.0450875945073137 1.0 0.4846766759928842 14 O15020,Q9NZJ7,Q9NW15,O43681,Q96RR1,P00846,O14773,P07602 8 +Hand polydactyly 0.4338612820969851 2.002315004255125 0.0452508632939385 1.0 0.4846766759928842 37 Q10713,P21964,O75845,Q13045,Q5H8A4,Q9UHX1,Q15067,Q15125,Q14739,P98175,Q96J42,O96028,O95202 13 +Centrally nucleated skeletal muscle fibers 0.6614956251011479 2.0000695972864113 0.0454927491698611 1.0 0.4846766759928842 9 P51114,Q13586,P50570,Q9BPX6,P22626,Q9H173 6 +Slow decrease in visual acuity 0.6612962967866164 1.9989861407197076 0.0456098534333155 1.0 0.4846766759928842 9 P03886,P00846,Q969G3 3 +Periventricular white matter hyperintensities 0.6609664541150864 1.997193008398781 0.0458042202815613 1.0 0.4846766759928842 9 O75503,P07602,P17900 3 +Ovoid vertebral bodies 0.6721041263461983 1.9971156784984565 0.0458126181389622 1.0 0.4846766759928842 8 P54802,P16278 2 +Polar cataract 0.8744564888338826 1.9922774983374003 0.0463406191729345 1.0 0.4891509801587533 4 P08670,Q7LGA3 2 +Abnormality of alkaline phosphatase level 0.4622646645942308 1.9899631712838477 0.0465949926196151 1.0 0.4901763629488141 27 Q8N511,Q92643,O75845,Q96A33,Q9UJS0,P22413,Q14739,Q96AY3,P22626,P14314,P51798 11 +Barrel shaped chest 0.7663157940784076 1.9894789518142824 0.0466483627897582 1.0 0.4901763629488141 6 Q32P28,Q14739,Q7RTS9 3 +Postaxial foot polydactyly 0.6307936531578252 1.98620991752833 0.047010020100568 1.0 0.4917565024003246 11 Q96J42,Q14739,O75845 3 +Abnormality of the 5th toe 0.6307936531578252 1.98620991752833 0.047010020100568 1.0 0.4917565024003246 11 Q96J42,Q14739,O75845 3 +Thickened ribs 0.8722143864598151 1.9829711419169491 0.0473706530880584 1.0 0.4933624845645048 4 P54802,P15586,P16278 3 +Abnormality of coordination 0.3283778626604456 1.9676170401259052 0.0491121176014885 1.0 0.5095231920990244 343 Q96D71,O14949,O75787,P50897,O75027,P00846,O43676,Q96TA2,P00374,Q9Y4P3,O15020,Q9P0J1,Q13510,O14773,P07602,Q53FT3,Q96CU9,P03886,Q9P0J0,Q14108,Q7KZN9,Q9H6K4,P33897,Q86Y39,Q9NZ08,Q5XKP0,P16278,Q9H2C2,Q01105,O95470,P04062,P00403,Q9NR77,Q9NQZ5,O75503,Q8IV08,Q6DKK2,Q96RL7,O60313,P12235,Q9Y619,Q13586,O00584,Q99720,P40855,Q9Y287,P35637,Q9NZJ7,O76024,P05067,Q9NVI7,P07196,O43292,Q9NPL8,O15118,O95202,Q9UID3,P55795,Q9NW15,Q9BUB7,Q7RTS9,O96000,Q5H8A4,Q5HYK3,O96028,Q96AA3,O75381,O14653,Q7LG56,O95721,Q9BPX6,Q9H9S5,P21912,Q06787,O00754,Q9UP83,Q9Y487,Q9NP80,Q03252,Q10713,Q969G3,O00429,Q13217 83 +Coxa valga 0.4638582855566598 1.966071922695289 0.0492903031685763 1.0 0.5095231920990244 25 P51812,Q8WTW3,Q9Y619,O75844,Q04656,O00754,Q96A33,Q15643,Q9H173,P02545,P22413,P16278 12 +Abnormal peripheral myelination 0.426464739786171 1.9643287454553409 0.0494919801993403 1.0 0.5095231920990244 38 P07196,Q8TB36,P50570,Q9NZJ7,Q7LG56,O43681,P03886,P02545,Q96RL7,Q9NR77,P20700,P00846,O15269,P07602 14 +Abnormal arterial physiology 0.4520441123673139 1.9643203781722476 0.0494929499196268 1.0 0.5095231920990244 30 O75844,Q9Y4P3,P02545,P01889,O15460,Q9NZ08,P22413,Q14739,P05067,P06280,Q9NWM8 11 +Abnormal circulating citrulline concentration 0.8125714611539502 1.963534460158852 0.0495841044083475 1.0 0.5095231920990244 5 P03886,P00846 2 +Progressive psychomotor deterioration 0.6652339566400035 1.960525934417538 0.0499343497640947 1.0 0.5116445910780474 8 Q10713,Q9NZJ7,O43681,P21912,P07602,P16278 6 +Abnormal intraocular pressure 0.701413200533562 1.95461945882499 0.0506280028219521 1.0 0.5116445910780474 7 Q8NCH0,P04439 2 +Abnormal myocardium morphology 0.2933274200826419 1.950717894194766 0.0510906135268529 1.0 0.5125577714816821 186 Q8WXH0,P23786,O75381,Q96IX5,Q86Y39,P13473,Q7LG56,P02545,P00846,Q9NZ08,O43676,O76024,P06280,Q5XKP0,Q9NVI7,Q9H9S5,P16278,Q9Y4P3,Q53H12,P04062,P54802,P49327,P00403,P21912,P22413,Q9NPL8,Q07021,Q96CU9,Q9C0B1,Q16836,P50402,P10253,Q9BTV4,P03886,Q96I36,Q96RL7,P42167,Q13423,O60313,P50416,Q96RR1,Q9BT22,Q9Y6M9,Q9BUB7,Q9NWS8,Q9H061,O96000,P12235,P08236,P01889,Q9P0J0,Q14108,Q7KZN9,P40855,P09493,P15586 56 +Basal ganglia cysts 0.7003538200377111 1.949285047344338 0.0512613932517838 1.0 0.513165130294739 7 P00846 1 +Eyelid myoclonus 0.6510750494360741 1.943270291322313 0.0519835090655118 1.0 0.5167405369519286 9 P00374,Q13510 2 +Fluctuations in consciousness 0.6988625796922876 1.9417712820386832 0.0521647949205321 1.0 0.5167405369519286 7 P03886,P04062 2 +Optic disc pallor 0.4387434733065337 1.937153206401805 0.0527266183237531 1.0 0.516904713627282 53 Q96CU9,Q10713,Q6P4Q7,Q86Y39,O00754,P03886,O00429,O60313,Q9H061,P04439,P00846,Q9NPL8,O43676,Q9H6K4,O96000,Q86WC4,Q9Y287 17 +Skeletal muscle hypertrophy 0.4342379568667465 1.934226494386955 0.0530852862349513 1.0 0.516904713627282 48 Q9Y4P3,P61978,Q9C0B1,Q05086,Q10713,P10253,P50570,Q96A33,O00754,P35250,P02545,Q9NR77,P21912,P07686,Q7LGA3,O94905,Q9H9S5,P16278 18 +Microretrognathia 0.5241305532920955 1.9333768470640913 0.0531897913092402 1.0 0.516904713627282 18 Q15125,Q9BUB7,Q8NCH0,Q9UHX1 4 +Abnormal lower limb bone morphology 0.2938329776438462 1.93060200986257 0.0535322891339675 1.0 0.516904713627282 191 Q03164,Q9NZJ7,Q32P28,Q9UHX1,O75787,P06280,Q15392,Q9H9S5,P16278,Q9UPT5,Q96A33,P04062,Q13510,P22413,Q06787,P07602,O95202,P51812,Q9NX62,P21964,O75845,O00754,Q15643,Q15125,O43505,P13073,P98175,Q96J42,Q9Y487,Q7RTS9,Q8N0X7,O75844,Q8WTW3,Q9Y619,P16435,P08236,Q03252,Q96HY6,Q10713,Q5H8A4,Q14739,Q7LGA3,Q96AY3,O96028 44 +Infantile spasms 0.4267654195747477 1.9299600472887064 0.0536117882796407 1.0 0.516904713627282 37 P03886,P00846,Q13510 3 +Abnormal endocrine physiology 0.8039021347030468 1.925581137288699 0.0541566958601591 1.0 0.520866568655043 5 Q13423 1 +High frequency sensorineural hearing impairment 0.8033099303860098 1.9229836465528 0.0544821036720986 1.0 0.5218399024560061 5 O75844,Q13510 2 +Respiratory distress 0.4407331640788652 1.9210141706789547 0.0547299210047436 1.0 0.522315583249849 58 P23786,Q9Y619,P10253,P51571,Q9NZJ7,Q969X5,Q13510,Q9UHX1,P04062,P03886,Q15643,Q99758,P00846,P22413,Q16134,P53701,P51970,P07602 18 +Hypomimic face 0.5466862799225782 1.9192186140438856 0.0549566727722987 1.0 0.522315583249849 15 P04062,Q7LG56,Q15043,O75787,Q96RR1,P12235 6 +Atrophy degeneration involving the spinal cord 0.6434755588177536 1.9184529557697487 0.0550536018236036 1.0 0.522315583249849 10 P07196,P33897,Q13217,P20700 4 +Duplication involving bones of the feet 0.4790967750691811 1.917392497585693 0.055188086642623 1.0 0.522315583249849 23 P21964,O75845,Q15125,Q14739,Q96J42,O96028,O95202 7 +Hemivertebrae 0.5730618757287073 1.9077885138201016 0.0564185559277046 1.0 0.52525675568693 13 Q9Y619,P16435,Q9UHX1,Q15125,Q9UM00,Q12768 6 +Abnormal sella turcica morphology 0.6549036543872585 1.905257407305161 0.0567466191349732 1.0 0.5262061993492042 8 O00754,Q7RTS9,P16278 3 +Abnormal mitochondria in muscle tissue 0.4858051344965561 1.8928192333388716 0.0583819129087206 1.0 0.5363853473101805 22 Q96CU9,Q86Y39,P03886,P00403,Q9NPL8,O43676 6 +Abnormal esophagus physiology 0.3057349779583623 1.892529342914422 0.0584204878810443 1.0 0.5363853473101805 244 Q96D71,P33897,P35637,Q13045,Q03164,Q9NZJ7,Q7LG56,Q9UHX1,Q8IZA0,O14678,P00846,O76024,P05067,P06280,Q9H2C2,Q01105,Q96A33,Q9Y584,Q9P0J1,Q13510,P04062,Q9NR77,P21912,Q06787,Q6ZXV5,O15118,P07602,O95202,P21964,P51571,P55795,Q96PU5,P03886,Q96RL7,O60313,O60220,P12235,Q6NUK1,Q9Y619,P16435,Q99720,O00429,Q99758,Q14108,Q14739,O15269,O96028,P15586 48 +Memory impairment 0.4249856107373708 1.8894226970857055 0.0588352119647432 1.0 0.5381300969743731 43 P33897,Q969G3,Q9UJS0,Q9NZJ7,Q7LG56,Q9BRK0,P49327,P00403,O43681,P03886,Q96RR1,Q9NZ08,P01889,Q06787,P05067,P07602 16 +Depletion of mitochondrial dna in muscle tissue 0.7447985703590607 1.8893740708512603 0.058841722741129 1.0 0.5381300969743731 6 Q7LG56,Q9UBX3,P12235 3 +Functional abnormality of the inner ear 0.3100028409521193 1.8813523466406803 0.0599240046273406 1.0 0.5431487096919447 265 P33897,O75381,Q86Y39,P35637,Q16740,Q9NZJ7,Q7LG56,P02545,P00846,Q9NZ08,O43676,O76024,P06280,P51572,Q5XKP0,O95721,P23634,P07196,Q9Y4P3,O95470,P98164,P04062,P49327,Q13510,P00403,Q15043,Q9NR77,P21912,P22413,Q9NPL8,Q07021,P07602,O95202,P51812,Q96CU9,Q9C0B1,O00754,P03886,O43681,P42167,O60313,Q15125,Q96RR1,Q9P2J5,Q13217,Q9UG56,Q9UP83,Q9NWM8,P38159,Q9NP80,Q9H061,P42892,O60220,P12235,O75844,O96000,Q9NR28,Q5JRA6,O00584,O00429,Q15067,P20700,P01889,Q15904,O15460,P09493,Q7LGA3,P40855,P33527,O15269,O96028,Q96AA3 72 +Insidious onset 0.7938192513679844 1.881272040490958 0.059934922346339 1.0 0.5431487096919447 5 Q9NR77,P04062,O60313 3 +Undetectable electroretinogram 0.8476849275727864 1.8806534268762911 0.060019078929927 1.0 0.5431487096919447 4 P50897,O14773 2 +Peripheral axonal neuropathy 0.4389512132574753 1.87690843468458 0.0605306446405922 1.0 0.5431487096919447 62 P07196,P12235,P33897,Q9NZJ7,Q7LG56,P00403,P07602,Q96RL7,P03886,O60313,P00846,O76024,Q9BPX6,O15269,Q9NVI7,Q8IV08 16 +Hallucinations 0.4286312167740511 1.8751008813113108 0.0607788463436285 1.0 0.5431487096919447 48 Q9BQE5,P35637,P21964,Q6DKK2,Q9NZJ7,P04062,O60313,P50897,O76024,O75503,P07602 11 +Supranuclear gaze palsy 0.4925025553841249 1.8728082910942825 0.0610948626637846 1.0 0.5431487096919447 21 P35637,Q9NZJ7,P04062,Q96RL7,Q99720,P07602 6 +Pace of progression 0.2953723405771163 1.8682678924365588 0.0617247396338569 1.0 0.5464553008946418 184 Q96D71,P33897,O43707,O14653,Q7LG56,Q8N1F7,P02545,O75787,Q5JTV8,O00400,Q5XKP0,P05023,P07196,Q8TB36,O95470,O15020,P04062,Q13126,Q13510,P54802,Q9BRK0,Q15043,Q9NR77,Q9NQZ5,O14773,Q8IV08,P27544,P50402,Q9BTV4,O14979,Q96RL7,Q96D53,O75569,O60313,Q96RR1,Q14203,Q9Y6M9,Q9NP80,P12235,Q9NR28,Q03252,Q10713,Q13586,O00584,Q99720,O00429,P20700,Q9P0J0,Q14108,P15586,Q12768 51 +Generalized clonic seizure 0.6837244208837006 1.865184304074786 0.0621555748634752 1.0 0.5479720317349864 7 P07602 1 +Occipital encephalocele 0.7899796571246531 1.8643524589762437 0.0622722244442122 1.0 0.5479720317349864 5 O43505,Q9H9S5,Q6ZXV5 3 +Reduced tendon reflexes 0.2908579985282183 1.8635055563771152 0.062391171530524 1.0 0.5479828367445088 191 Q8WXH0,O75381,Q8TD16,P35637,Q13045,O14653,Q969X5,Q9NZJ7,Q7LG56,P02545,O75787,P00846,O95721,Q9H9S5,P05023,Q9H2C2,P07196,Q8TB36,P04062,P54802,Q13510,Q9UBB4,Q9NR77,Q06787,P07602,P51114,P50402,P10253,O14979,Q9BTV4,P03886,O43681,Q96RL7,Q9HC21,O60313,P50416,Q96RR1,O43505,Q9BT22,Q13217,Q9BQT8,Q9NWS8,Q9H173,P12235,Q10713,Q8TAA9,Q13586,Q99720,O00429,Q5H8A4,Q15067,P40855,Q96AY3,O15269,Q9H6K4 55 +Abnormal vascular physiology 0.4346013260223211 1.8550310693356655 0.0635917899756377 1.0 0.5566088055870428 58 P02545,Q8IZA0,Q9NZ08,O14678,P05067,P06280,Q9Y4P3,P04062,P49327,P00403,P22413,P03886,Q9NWM8,P51970,O96000,Q6NUK1,Q8WTW3,O75844,P01889,O15460,Q14739,Q14108 22 +Incomplete penetrance 0.4397229913243522 1.8487564012721895 0.0644929954596931 1.0 0.5607891822359563 30 O43707,O14979,P03886,Q969G3,O60313,P21912,P00846,Q06787,Q92733 9 +Ascites 0.4315173995208267 1.8482092804359431 0.0645720734003163 1.0 0.5607891822359563 33 P08236,P04062,Q13510,O75787,Q14739,Q14108,O15118,Q01844,Q86WC4 9 +Coronal craniosynostosis 0.6796917734972627 1.844687945595632 0.0650829453977817 1.0 0.5628566919216526 7 P07237,P16435,Q9NX62 3 +Hypometric saccades 0.8389662802210059 1.8440704063299185 0.0651728801172439 1.0 0.5628566919216526 4 P04062,Q5HYK3 2 +Impaired distal vibration sensation 0.6326514749535351 1.842075275018652 0.065464139856616 1.0 0.5640222218679732 9 Q9BRK0,P33897,Q06787,P20700 4 +Abnormal larynx morphology 0.4413939549401318 1.8414873966567316 0.0655501658497472 1.0 0.5640222218679732 29 Q96HY6,P21964,Q9NZJ7,Q13510,Q9UHX1,Q14739,P07602 7 +Abnormal morphology of the conjunctival vasculature 0.6322769123654212 1.840007881877341 0.0657670801597332 1.0 0.5648445722205868 9 P06280,P10619 2 +Thoracic kyphosis 0.5171095144289466 1.836631004524234 0.0662643870354442 1.0 0.5653214332099921 17 P51648,O00754,P04062,Q9UHX1,Q7RTS9 5 +Pericarditis 0.783633766031025 1.8363332934944288 0.0663083786321494 1.0 0.5653214332099921 5 P01889,O15460,Q9NZ08 3 +Vertebral segmentation defect 0.426806930066809 1.831079347435755 0.0670887006151377 1.0 0.5701173272641348 34 Q8WTW3,Q9Y619,Q9Y4P3,P61978,P16435,Q12768,Q8TAA9,Q8N3U4,Q9UHX1,P35250,Q15125,P22413,Q9UM00,O96028,O95202,Q9H9S5 16 +Heparan sulfate excretion in urine 0.8351453817395533 1.8280036768219257 0.0675489998287912 1.0 0.5703042383236954 4 P54802,P15586 2 +Axonal degeneration 0.6401528347909251 1.8258280028778429 0.0678761738225313 1.0 0.5703042383236954 8 Q8TB36,P33897,Q6DKK2,P50570,Q9BQT8 5 +Abnormal circulating non proteinogenic amino acid concentration 0.639990878627921 1.82495264443152 0.0680081758471353 1.0 0.5703042383236954 8 Q9Y619,P03886,P00846 3 +Abnormal autonomic nervous system physiology 0.4259612305092874 1.8226945046331855 0.0683496730818007 1.0 0.5703042383236954 34 Q04656,Q9NZJ7,P04062,O43681,Q96RL7,P20700,Q15067,P42892,Q06787,O76024,P06280,P07602 12 +Low plasma citrulline 0.9791372991260204 1.818134640134539 0.069043556687415 1.0 0.5703042383236954 2 P00846 1 +Multiple glomerular cysts 0.9791372991260204 1.818134640134539 0.069043556687415 1.0 0.5703042383236954 2 P00846 1 +Retinal arterial tortuosity 0.9791372991260204 1.818134640134539 0.069043556687415 1.0 0.5703042383236954 2 P00846 1 +Leber optic atrophy 0.9791372991260204 1.818134640134539 0.069043556687415 1.0 0.5703042383236954 2 P00846 1 +Primary adrenal insufficiency 0.5230931954892561 1.8156509595160557 0.0694239312183571 1.0 0.5703042383236954 16 P16435,O75381,P33897,Q13423,P40855 5 +Sensory neuropathy 0.4155006742020596 1.8141740917245024 0.069650927556325 1.0 0.5703042383236954 37 P03886,Q96RL7,P00403,O60313,P00846,P51797,O60220,Q8IV08 8 +Peripheral neuropathy 0.2928092931016646 1.8116126748666357 0.070046065096518 1.0 0.5703042383236954 184 Q9Y2R0,P33897,Q13045,Q5KU26,Q9NZJ7,Q7LG56,P00846,O76024,O95721,Q9NVI7,Q86WC4,Q9BPX6,P07196,O95470,P54802,P00403,Q9NR77,Q9NPL8,Q06787,P07602,Q8IV08,Q96CU9,Q16836,Q9HC21,P03886,Q96RL7,O60313,Q9NWS8,O60220,P12235,Q10713,O00429,Q9P0J0,Q7KZN9,P51797,O15269 36 +Leg muscle stiffness 0.7776860495003511 1.81001055299642 0.0702941506695138 1.0 0.5703042383236954 5 P33897,P00846 2 +Saccadic smooth pursuit 0.7775491821190421 1.8094041271799095 0.0703882424562656 1.0 0.5703042383236954 5 O14773,Q9NW15,Q06787 3 +Stroke 0.4182479314843898 1.808214080049146 0.0705731880669877 1.0 0.5703042383236954 36 O75844,P05067,Q9Y4P3,Q13586,P03886,P00403,P02545,P22413,O76024,O95721,P06280,Q96AA3 12 +Corpus callosum atrophy 0.530389296877498 1.8080123949497915 0.070604571479153 1.0 0.5703042383236954 15 O00754,O75503,O00429,O60313,P20700,P51572 6 +Dilated cardiomyopathy 0.4222349348708868 1.8073098703291277 0.0707139779193457 1.0 0.5703042383236954 48 Q8WXH0,P23786,P13473,Q7LG56,P02545,P00846,Q9H9S5,P16278,P42166,P00403,Q16836,Q9BTV4,P03886,Q96RL7,P42167,Q96RR1,P53701,P12235,P09493 19 +Vascular tortuosity 0.8293883229074714 1.803756637171932 0.0712694664086397 1.0 0.5703042383236954 4 P03886,P00846 2 +Type ii transferrin isoform profile 0.8293370944992957 1.8035406709979624 0.0713033440825758 1.0 0.5703042383236954 4 Q15904,Q9UP83,O75787 3 +Erlenmeyer flask deformity of the femurs 0.8286620247701346 1.8006944069450468 0.0717510596553623 1.0 0.5708573622599455 4 P04062,P07602 2 +Abnormal acetabulum morphology 0.4651886485540784 1.800580461525142 0.0717690310377392 1.0 0.5708573622599455 23 Q8WTW3,Q9Y366,P08236,Q9Y584,Q969X5,Q15643,O75718,Q96AY3,Q7RTS9,P16278 10 +Joint stiffness 0.430688633550103 1.7992385744977608 0.0719809499708568 1.0 0.5708573622599455 60 Q8WXH0,Q13045,P02545,O76024,P16278,Q9Y4P3,P51648,P54802,P50402,O00754,Q15022,O75844,P08236,P16435,Q8TAA9,P01889,O15460,Q96AY3,P15586 19 +Abnormal endocardium morphology 0.5289931023131084 1.7984337503082155 0.0721082983907299 1.0 0.5708573622599455 15 Q9Y4P3,P04062,P49327,P01889,P22413,Q9NZ08,P06280,P10644 8 +Abnormal retinal vascular morphology 0.4253118416059549 1.7938111268095058 0.0728433203695821 1.0 0.5737489954659984 53 Q9Y4P3,Q96S66,P17900,P21964,Q9NZJ7,P03886,Q13510,P21912,P04439,P00846,P06865,P10619,P07602,P16278,P38435 15 +Atrophy degeneration affecting the cerebrum 0.3071034799164283 1.7907364812791815 0.0733355925241845 1.0 0.5757142031379419 270 Q96D71,Q8TD16,Q5KU26,Q9NZJ7,Q9UHX1,O75787,P50897,O14678,P00846,O76024,P05067,O00400,Q9H490,P00374,Q86WC4,P16278,Q9H9S5,Q9H2C2,Q9UGJ1,Q01105,P17900,Q9UPT5,Q96A33,P04062,P00403,Q15043,Q06787,O14773,O75503,P07602,P51812,O75208,O75845,Q6DKK2,O00754,P03886,Q96RL7,O60313,Q9BT22,P13073,Q9BUB7,Q9UP83,Q9NWS8,O60220,Q9Y619,Q96N66,Q16625,Q10713,O00429,Q5H8A4,Q9Y320,Q7LGA3,P40855,Q13217,Q96AA3 55 +Abnormal periventricular white matter morphology 0.4156006578586759 1.790707928877569 0.0733401766833081 1.0 0.5757142031379419 43 P33897,P17900,P51571,Q9NZJ7,Q9UHX1,O60313,O95202,O75503,O96028,P07602,Q9H9S5,Q53FT3 12 +Psychosis 0.4192575332378736 1.7862336680518174 0.0740614318788104 1.0 0.5785743186763217 35 P51812,P33897,Q6DKK2,P03886,P00403,Q96RL7,O76024,Q9Y287 8 +Abnormal activity of mitochondrial respiratory chain 0.4281286117192011 1.785024289970902 0.0742573770495798 1.0 0.5785743186763217 58 Q9Y2R0,Q96CU9,P03886,Q9Y584,Q70HW3,Q9P0J0,P13073,Q9UBX3,Q7KZN9,O43676 10 +Cystic liver disease 0.6324549676840717 1.7841449475215068 0.0744001152232387 1.0 0.5785743186763217 8 Q9UGP8,Q9UBS4,P14314,Q96J42 4 +Generalized joint laxity 0.5718996891835093 1.783219248091336 0.0745506203885697 1.0 0.5785743186763217 12 Q8NCH0,Q9UHX1,Q9Y487 3 +Abnormal delivery 0.4630840134094043 1.782803964178953 0.0746182202465224 1.0 0.5785743186763217 23 O75844,Q9Y619,P50570,Q969X5,P02545,O60313,Q01082,P22413,Q9Y487 9 +Gait ataxia 0.4351419443595724 1.78134022724361 0.0748568865493526 1.0 0.5785743186763217 77 Q9NZJ7,Q7LG56,P00846,Q9NVI7,P07196,O15020,Q9P0J1,Q9UBB4,Q9NR77,O43292,Q06787,O15118,O14773,P07602,Q8IV08,Q9UID3,O00754,P03886,O43681,Q9NW15,Q96RR1,Q9H173,P12235,Q03252,Q10713,Q5H8A4,P20700,Q14108,Q13217 29 +Glomerulopathy 0.6188283084576518 1.7808158202884492 0.0749425440867976 1.0 0.5785743186763217 10 Q03252,P02545,P01889,Q14108,Q9NZ08,P06280 6 +Abnormal caudate nucleus morphology 0.5715055057878153 1.7807858866672543 0.0749474359101658 1.0 0.5785743186763217 12 P00846,Q96RL7 2 +Skin nodule 0.452790610810787 1.7776026775501357 0.0754691337336987 1.0 0.5816371151165031 24 P16615,P35637,Q13510,P01889,P21912,Q9NZ08,P22413,P06280 8 +Abnormal pupillary function 0.6208056900526949 1.7765042220477003 0.075649846646975 1.0 0.582066175440775 9 Q13586,Q9NR77,P07602 3 +Abnormal muscle fiber protein expression 0.6306031652536861 1.7740944830248428 0.0760475232038628 1.0 0.5823893746414064 8 Q8WXH0,P02545,Q9H9S5,P50402 4 +Abnormal liver morphology 0.3052839097332631 1.7739756167465988 0.0760671836266326 1.0 0.5823893746414064 265 P23786,O75381,Q86Y39,P09601,Q9NZJ7,Q7LG56,Q9UJW0,P00846,O43676,Q5XKP0,P00374,Q9HC07,P16278,Q9NVI7,Q8N511,Q86WC4,Q96A33,P04062,P54802,Q13510,Q16134,Q9NPL8,O15118,Q01844,P07602,P22830,Q96CU9,O75312,Q16836,O75845,P10253,O00754,Q9HC21,P03886,Q96I36,Q96RL7,Q9BT22,Q9BUB7,Q96J42,Q9UP83,Q9NWS8,O96000,P10619,Q9Y619,P08236,Q03252,Q16625,Q96HY6,Q15904,Q14108,Q7KZN9,Q14739,P40855,P15586,Q96AA3 55 +Abnormal morphology of the limbic system 0.5699572659075925 1.7712234137905172 0.0765235572153377 1.0 0.5827347211842664 12 Q86WC4,Q96RL7,Q01105 3 +Atrophy degeneration affecting the brainstem 0.5326558220364223 1.7702509565357194 0.0766853440709174 1.0 0.5827347211842664 14 O00429,O60313,P20700,Q96RR1,Q9UP83,Q13217 6 +Premature rupture of membranes 0.7193140715677853 1.769590819942627 0.0767953292348773 1.0 0.5827347211842664 6 O75844,Q9Y487 2 +Abnormality of lysosomal metabolism 0.7683535433038222 1.76859022922538 0.0769622824987057 1.0 0.5827347211842664 5 P07602,Q13510 2 +Abnormal atrioventricular conduction 0.5246165766334374 1.7683573104608667 0.0770011885055956 1.0 0.5827347211842664 15 Q8WXH0,P50402,Q7LG56,P02545,P21912,Q9HD47,P06280 7 +Entropion 0.6162841728938812 1.7665113995795885 0.0773100907873063 1.0 0.5827347211842664 10 O75844,P30153,P01889,P36543 4 +Paresthesia 0.4394481421767023 1.7648073272431817 0.0775961527863493 1.0 0.5827347211842664 26 P07196,Q7LG56,P54802,P01889,Q9NR77,O15460,Q9NZ08,P05067,P06280,Q9H6K4 10 +Endocarditis 0.7666478555304582 1.7610046779985191 0.0782376112304894 1.0 0.5828234608849003 5 P01889,Q9NZ08,P04062,P49327 4 +Abnormal echocardiogram 0.7169304384606269 1.7583222451798783 0.0786926947478465 1.0 0.5841386563094306 6 Q96RR1,Q969Y2,Q7LG56,P12235 4 +Respiratory insufficiency 0.2872927878900279 1.757659945781988 0.0788053869306815 1.0 0.5841386563094306 195 P23786,O75381,Q8TD16,Q86Y39,P35637,P13473,Q9NZJ7,Q7LG56,O43676,O76024,P06280,Q5XKP0,Q86WC4,Q9H9S5,Q53H12,Q92804,Q13510,Q9NR77,Q9NPL8,P07602,Q15165,Q96CU9,O75208,P50402,P10253,P03886,Q96I36,Q9BT22,Q9BUB7,Q7RTS9,O96000,P12235,Q6NUK1,Q9Y619,Q13586,Q70HW3,Q14739,P40855,Q96AY3,P51797,Q96AA3 41 +Confusion 0.4931302463876896 1.753384796746397 0.079535978867306 1.0 0.5858227557394138 19 Q9Y619,P33897,Q16836,O00754,Q9UJS0,P49327,P01889,Q9NZ08,P05067 9 +Pulmonary infiltrates 0.6256518790977995 1.747178499240755 0.0806063800750409 1.0 0.5909018885815994 8 P01889,P04062,Q9NZ08,Q13510 4 +Hypotension 0.4308696629057737 1.7429733102586622 0.0813382770147632 1.0 0.5927140030108248 29 Q04656,Q9NZJ7,P04062,O43681,Q13423,P20700,Q99758,Q14203,P07686,Q06787,P29992,P07602 12 +Focal segmental glomerulosclerosis 0.4387768798292784 1.7424077249829284 0.0814371251451346 1.0 0.5927140030108248 25 O43707,O95470,P03886,P00403,Q8N1F7,Q96D53,Q14108 7 +Acquired abnormal hair pattern 0.6596427049040308 1.7422165652568695 0.0814705564317186 1.0 0.5927140030108248 7 O75844 1 +Epiphyseal stippling 0.5470796512087341 1.74137683580157 0.0816175458496109 1.0 0.5927140030108248 13 O75381,Q15125,Q14739,P40855,P38435 5 +Decerebrate rigidity 0.8140413396302992 1.7388985440139049 0.0820526103874723 1.0 0.5940200643136606 4 P07602,P16278 2 +Thoracic scoliosis 0.5880049461190258 1.736382272710154 0.0824962646313711 1.0 0.595695626704712 11 Q9UHX1 1 +Mask like facies 0.5274364022607699 1.735137090899204 0.0827165259761275 1.0 0.595695626704712 14 Q04656,P04062,O75787,Q14203,Q06787,Q9H9S5 6 +Abnormal circulating proteinogenic amino acid derivative concentration 0.4353905900697032 1.7279189082142516 0.0840027638674254 1.0 0.5988252156246026 26 O75880,O75208,P03886,Q7LG56,Q9P0J1,Q9P0J0,P00846,Q9BUB7,Q9NP80,Q5XKP0,O96000 11 +Cerebral white matter atrophy 0.4559214986096717 1.722117081980559 0.0850483113055813 1.0 0.6025873502701387 23 O00754,O00429,O60313,P20700,Q9UP83,P51572,O75503 7 +Cachexia 0.4726701534031627 1.7142461726057512 0.0864835242614632 1.0 0.6066200791696666 21 P35637,Q9NZJ7,Q7LG56,P04062,Q99720,P07602 6 +Hyperacusis 0.6189247227838526 1.7105091463999076 0.0871717635560207 1.0 0.6066200791696666 8 Q13045,P17900 2 +Subcutaneous nodule 0.4872647027371487 1.7086466032828305 0.0875164305686933 1.0 0.6066200791696666 19 P35637,Q13510,P01889,P21912,Q9NZ08,P22413,P06280 7 +Bilateral tonic clonic seizure with generalized onset 0.608374031929348 1.707282931683565 0.0877694770060713 1.0 0.6066200791696666 9 P04062,Q13510,Q5HYK3 3 +Choreoathetosis 0.4079294838238644 1.702601496936044 0.0886426697574576 1.0 0.6066200791696666 36 Q9H6K4,Q9P0J0,Q5XKP0,P00846 4 +Sound sensitivity 0.6073730475855775 1.7016917540634728 0.0888131670040206 1.0 0.6066200791696666 9 Q13045,Q9Y4P3,Q9GZY8,P17900 4 +Abnormality of the anterior fontanelle 0.4045436099594808 1.700509738348062 0.0890350862095816 1.0 0.6068020267580002 37 P51812,Q6NUK1,Q9Y619,P16435,O75381,P36543,Q04656,P98164,Q32P28,Q15125,Q16134,Q9Y487,P40855,P42345 14 +Abnormal circulating pyruvate family amino acid concentration 0.4438846119131809 1.699830850562625 0.0891627467889306 1.0 0.6068020267580002 24 O75208,P03886,Q7LG56,Q9P0J1,Q9P0J0,P00846,Q9BUB7,Q9NP80,Q5XKP0,O96000 10 +Angina pectoris 0.7523993341927215 1.6974606627997977 0.0896096020945544 1.0 0.6089528434308775 5 O75844,P06280,P22413 3 +Positive romberg sign 0.6036445772983067 1.6951879232916771 0.0900397771417971 1.0 0.6101054981490529 10 Q9H6K4,Q8IV08 2 +Focal t2 hyperintense brainstem lesion 0.4852199679479921 1.6930139758270646 0.0904528070073431 1.0 0.6120026404348582 19 Q96CU9,Q86Y39,P03886,Q9NPL8,O43676 5 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9478432478150508 1.6883964180462745 0.091335157615914 1.0 0.6125009128925334 2 O14773 1 +Emg neuropathic changes 0.4227710873789841 1.6879466116786035 0.0914214778754183 1.0 0.6125009128925334 30 Q96RL7,Q13510,O60313,Q9NR77,O14773,P07602 6 +Hypertriglyceridemia 0.4422009767776729 1.6850764567754102 0.0919738212914889 1.0 0.6125009128925334 24 Q8WXH0,P22830,O95470,P50402,Q13045,Q9BTV4,P28070,P02545 8 +Low frustration tolerance 0.5789857765117157 1.6830168914323318 0.0923718215331967 1.0 0.6142726131957587 11 P04062,Q9UHX1 2 +Preaxial hand polydactyly 0.5378928731404333 1.6819666525129158 0.0925753065571253 1.0 0.6147475777794841 13 O95202,Q5H8A4,Q9UHX1,Q96J42 4 +Clonic seizure 0.6124173161055212 1.6749314235793775 0.0939476873550964 1.0 0.6212559072571262 8 Q01082,Q9NZJ7,P07602 3 +Abnormal brainstem mri signal intensity 0.459286429337401 1.674890180446376 0.0939557806034407 1.0 0.6212559072571262 22 Q96CU9,Q86Y39,P03886,Q9NPL8,O43676 5 +Negativism 0.9441781787425932 1.673159020393032 0.0942959952408233 1.0 0.6217391754193097 2 Q9BQE5 1 +Social and occupational deterioration 0.9441781787425932 1.673159020393032 0.0942959952408233 1.0 0.6217391754193097 2 Q9BQE5 1 +Acetabular dysplasia 0.599558823002375 1.6720435813945786 0.094515728534986 1.0 0.6219712373236899 10 P08236,Q9Y584,P16278 3 +Muscle fiber atrophy 0.458670704709878 1.669785624062457 0.0949617856799056 1.0 0.6220522840181696 22 Q8WXH0,P23786,P61978,P35637,P50402,Q9BTV4,Q13586,Q99720,Q96RL7,P02545 10 +Segmental peripheral demyelination remyelination 0.6981649552894118 1.6692412664976737 0.0950695748743708 1.0 0.6220522840181696 6 Q9NR77,P03886,P00846 3 +Micrographia 0.9424866084014668 1.666123792907899 0.0956887604733869 1.0 0.6233478768318312 2 P04062 1 +Furrowed tongue 0.6009654054113769 1.665840623115724 0.0957451626068226 1.0 0.6233478768318312 9 P21912,P61978,Q96J42 3 +Abnormality of the cerebrospinal fluid 0.3500454286908766 1.6651355843401574 0.0958857087947389 1.0 0.623391025753505 157 P23786,Q86Y39,Q9NZJ7,Q7LG56,P00846,O43676,Q15392,Q86WC4,Q9H9S5,P07237,P04062,P00403,Q9NR77,Q9NPL8,P07602,O95202,Q96CU9,P30153,O75312,P21964,O00754,Q9HC21,P03886,Q96I36,Q15125,O43505,P13073,Q96J42,Q9NWS8,O96000,Q6NUK1,P08236,P16435,Q16625,Q10713,Q03252,Q8TAA9,Q9P0J0,Q7KZN9,P40855,O96028 41 +Hamstring contractures 0.9419227516210896 1.6637783656054983 0.0961567289276186 1.0 0.6242811341116662 2 P33897 1 +Upper limb spasticity 0.5998660373850688 1.6596792987976785 0.0969789860470589 1.0 0.627519373356713 9 Q99720,Q12768,Q8N0X7,P35637 4 +Unexplained fevers 0.6432575644938758 1.6577985876879169 0.0973581264901697 1.0 0.628158166170763 7 P07602,Q9HC07 2 +Abnormality of metacarpal epiphyses 0.7433960895851923 1.657151201179952 0.097488909647738 1.0 0.628158166170763 5 P51812,P16435,O95202 3 +Abnormality of the shoulder girdle musculature 0.3969893564855895 1.6556203209842095 0.0977987323058462 1.0 0.628158166170763 38 Q8WXH0,P07196,Q8TD16,P50402,Q9BTV4,O14979,Q9NZJ7,Q7LG56,O00429,P02545,O60313,Q9Y487,P07602,Q9H9S5,P12235 15 +Incoordination 0.4242646948961576 1.6542747512357867 0.098071700671573 1.0 0.6288206151875652 79 P33897,Q9NZJ7,Q7LG56,O75787,P00846,Q9H9S5,Q01105,O15020,P04062,Q13510,Q9UBB4,Q9NR77,P21912,O75503,O14773,P07602,Q6DKK2,O00754,O43681,Q7RTS9,P12235,Q9Y619,Q10713,Q13586,Q15067 25 +Aplasia hypoplasia of the sternum 0.7930438611055666 1.6496716059098475 0.0990101206601525 1.0 0.6330935599903987 4 Q9Y619 1 +Widely patent fontanelles and sutures 0.7415676777206578 1.6489507042917235 0.0991577342112317 1.0 0.6331676992500465 5 O75844,P98175 2 +Aortic valve stenosis 0.5498371690629335 1.6462645355128254 0.0997093076214308 1.0 0.6358175712024116 12 O75844,P04062,Q15125,Q12768,P16278 5 +Fasciculations 0.3992410323833575 1.6411085261479637 0.1007748891942361 1.0 0.6391105029961435 41 P07196,P51114,Q8TD16,P35637,Q9NZJ7,Q9NW15,Q13510,P06280,Q9BQT8,P07602 10 +Hypoplastic vertebral bodies 0.691832579269818 1.6390396457306282 0.1012050032088451 1.0 0.6409650203226862 6 Q14739,P10644,P16278,Q8TAA9 4 +Visual fixation instability 0.7899570902506082 1.6365102802626208 0.1017328359356426 1.0 0.6425594997020577 4 Q13510 1 +Titubation 0.5704008520405752 1.6320115251339744 0.1026770583120977 1.0 0.6453469316969414 11 P35637,Q99720,Q96RL7,P20700,Q01082,Q6PJG6 6 +Nephrotic syndrome 0.4145122963443354 1.6311089597414246 0.1028673304659786 1.0 0.6453469316969414 31 Q03252,O95470,Q8NCH0,Q8N1F7,Q96D53,Q9BT22,Q14108,O95721,P06280 9 +Impaired vibration sensation in the lower limbs 0.4886444403072246 1.6299831250760035 0.1031050635387071 1.0 0.6459677937721157 17 Q9NR77,O00400,P33897,P00846 4 +Neuroinflammation 0.787832335264621 1.627444539854215 0.1036427184484434 1.0 0.6475277450757934 4 P01889,Q9NZ08 2 +Impaired social interactions 0.4081867236797851 1.6274017460192762 0.1036518009499694 1.0 0.6475277450757934 51 Q96CU9,O75746,Q86Y39,Q5KU26,P03886,Q9UHX1,Q9P0J0,Q9NPL8,O43676,Q5XKP0,O96000 11 +Episodic respiratory distress 0.9452222771090996 1.6268386825188037 0.1037713636576889 1.0 0.6475277450757934 3 P00846 1 +Photophobia 0.3965725646397455 1.6252509357586018 0.1041091012086974 1.0 0.6477962492519956 40 P51648,Q6P4Q7,Q9NZJ7,P01889,P04439,Q9NZ08,Q9Y287,Q86YV9,P07602,O60220,Q96S66 11 +Abnormality of corneal size 0.4039890970061887 1.6226213870733677 0.104670365722626 1.0 0.6495268729042062 47 O75845,Q13045,Q8NCH0,Q5H8A4,Q15125,O43505,Q96J42,Q9NWM8,O96028,O95202,Q9H9S5 11 +Generalized hyperkeratosis 0.7355804672798599 1.6220651214320243 0.1047894052741265 1.0 0.6495268729042062 5 O75844,P21912,P02545 3 +Abnormality of fontanelles 0.4074672117587439 1.6196178600117237 0.1053143906333924 1.0 0.6510471293472002 51 O75381,P36543,Q32P28,P02545,P98164,Q16134,P51812,Q8NCH0,Q15125,Q9BT22,P98175,Q9Y487,P42345,Q6NUK1,O75844,Q9Y619,P16435,Q04656,P20674,P40855 20 +Exercise intolerance 0.3966020956590817 1.6175235233712637 0.1057653221789067 1.0 0.651595815202037 37 P23786,Q9Y2R0,P13473,P03886,Q7LG56,P00403,Q9H2D1,P46020,P12235 9 +Abnormal lower motor neuron morphology 0.5921616963417531 1.616418662831126 0.1060038260090459 1.0 0.6518465126447934 9 Q99720,Q13510 2 +Hypopigmentation of the fundus 0.7339818588463406 1.6148782535681283 0.1063370624435677 1.0 0.6521726293475731 5 Q9Y619 1 +Abnormality of fundus pigmentation 0.7339818588463406 1.6148782535681283 0.1063370624435677 1.0 0.6521726293475731 5 Q9Y619 1 +Asymmetric septal hypertrophy 0.9289540456724013 1.6097890910886743 0.1074439075397952 1.0 0.6572183204661235 2 P54802 1 +Posterior polar cataract 0.9286721172822114 1.608614546143739 0.1077006515611986 1.0 0.6572183204661235 2 P08670 1 +Exaggerated startle response 0.5907453336023901 1.608450306540433 0.1077365914117556 1.0 0.6572183204661235 9 P16278,P17900 2 +Ventricular escape rhythm 0.6851755028702536 1.607216528031138 0.1080068775846583 1.0 0.6572183204661235 6 Q8WXH0,P02545,P50402 3 +Chorioretinal dysplasia 0.6326631989845188 1.6029144904485382 0.1089535340479845 1.0 0.6603889335851149 7 O43505,Q9NX14,P53701,Q9H9S5,Q9UGJ1 5 +Diastasis recti 0.7808401926611648 1.5975761345395674 0.1101373412581221 1.0 0.6650932331464058 4 Q8NCH0 1 +Abnormal basal ganglia mri signal intensity 0.4085950322904341 1.596999071543907 0.1102659141845163 1.0 0.6650932331464058 32 Q96CU9,P03886,Q9P0J0,P00846,Q7KZN9 5 +Wide cranial sutures 0.5981974863379406 1.596840900160944 0.1103011763671375 1.0 0.6650932331464058 8 O75844,P98175,P02545 3 +Hyperesthesia 0.9250070482097484 1.5933425109992865 0.1110833748809247 1.0 0.6680789535797221 2 P07602 1 +Abnormal heart rate variability 0.7785014856882008 1.5875742762861602 0.112382638826427 1.0 0.6750208822413135 4 P07602 1 +Multiple mitochondrial dna deletions 0.7773011786888584 1.5824387812964016 0.1135494373515779 1.0 0.6793992684724877 4 Q7LG56,P12235 2 +Nocturia 0.7773011786888584 1.5824387812964016 0.1135494373515779 1.0 0.6793992684724877 4 Q7LG56,P12235 2 +Slender long bone 0.4976912171178026 1.5817070004077516 0.1137164738766673 1.0 0.6795252707264271 15 Q9Y619,Q9H490,Q32P28,Q9Y487 4 +Neck flexor weakness 0.725900477484128 1.578495014353932 0.1144519326067883 1.0 0.6801441805559422 5 Q99720,P35637 2 +Increased bone mineral density 0.4134671713798769 1.5784521658841644 0.114461769000421 1.0 0.6801441805559422 29 Q9Y4P3,P04062,Q13126,P54802,Q15043,Q15125,P22413,Q14739,Q14108,Q15392,Q86WC4 11 +Demyelinating peripheral neuropathy 0.455876551407317 1.5784465755552857 0.114463052378285 1.0 0.6801441805559422 21 P07196,P03886,Q7LG56,Q9NR77,P00846 5 +Cerebral amyloid angiopathy 0.9213419791373 1.5780653440501584 0.1145505988304744 1.0 0.6801441805559422 2 Q9Y287 1 +Epistaxis 0.4887964133616219 1.572297199663039 0.1158816421869659 1.0 0.6825189325089283 16 P38435,Q13586,P04062,P01889,O15460,Q86YV9,P49257,P12814,P10644 9 +Hypokinesia 0.4958452808562293 1.568816041457643 0.1166908094704339 1.0 0.6842213204441979 15 P13473,P04062,P12235 3 +Abnormal facial expression 0.388718765255386 1.5676974005219588 0.11695176863283 1.0 0.6842213204441979 38 Q04656,Q6P1N0,P50570,Q969X5,Q7LG56,P04062,Q15043,O75787,Q9NR77,Q96RR1,Q14203,Q06787,Q9H9S5,P12235 14 +Peripheral hypermyelination 0.918804623625602 1.5674861079771407 0.1170011108643569 1.0 0.6842213204441979 2 Q9NR77 1 +Severe muscular hypotonia 0.4054271242405435 1.565804460556 0.1173944016674066 1.0 0.6856598993246902 32 O75381,O75746,Q01105,Q8TD16,Q5H8A4,O43505,P40855,Q9NWM8,Q9H9S5 9 +Focal t2 hyperintense basal ganglia lesion 0.4374359687729081 1.564217121130527 0.1177665877637306 1.0 0.6861119725158523 23 Q9P0J0,P03886,Q96CU9,P00846 4 +Underdeveloped supraorbital ridges 0.5581697133441943 1.5590115751236222 0.1189936405465266 1.0 0.6881197873491057 11 Q6NUK1,Q6PGP7,P16435,O75381,P52732,P98175,P40855 7 +Young adult onset 0.5356845208831021 1.5576501331884207 0.1193162075559146 1.0 0.6881197873491057 12 Q9NZJ7,P07602,P38435 3 +Atrophic scars 0.590962959053963 1.55693877398169 0.1194850225128125 1.0 0.6881197873491057 8 Q9NWM8,Q8NCH0 2 +Ulnar claw 0.7206903360808729 1.5549942623292503 0.119947435828809 1.0 0.689327547880378 5 P07196,Q9NR77 2 +Paraparesis 0.4037086414174748 1.5488562931191197 0.1214162696461846 1.0 0.6934880186539751 32 Q9Y619,P33897,Q6DKK2,P04062,Q9H6K4,Q13510,Q5XKP0 7 +Rigidity 0.4100358938575569 1.5467942877423733 0.1219128580898514 1.0 0.6952528007633975 64 Q9H2C2,Q96CU9,Q9NZJ7,Q7LG56,Q9BRK0,P04062,P07602,P00846,Q9Y287,Q9BPX6,Q9H6K4,Q15392,P16278,P12235 14 +Type 1 muscle fiber atrophy 0.5889131385937914 1.5456129802832546 0.1221980644558797 1.0 0.6952528007633975 8 Q8WXH0,P02545,Q9BTV4,P50402 4 +Hypothermia 0.5335786604586681 1.5444182846113852 0.1224870332899277 1.0 0.6952528007633975 12 P03886,P00846 2 +Abnormal conjunctiva morphology 0.4077671537707378 1.5440150302699216 0.1225846914870114 1.0 0.6952528007633975 30 P49327,Q13510,P28070,Q9NW15,P01889,P21912,Q9NZ08,Q14739,P06280,P10619 10 +Abnormal pelvis bone morphology 0.7178017836369366 1.5419509550773405 0.1230855122061851 1.0 0.6954574987525162 5 P16435,Q15643,Q7RTS9 3 +Abnormality of central nervous system electrophysiology 0.326457749734647 1.5416855185049547 0.1231500326948547 1.0 0.6954574987525162 165 P33897,Q9BQE5,O75381,Q13045,Q9NZJ7,P50897,Q9H2C2,P07196,Q96A33,P00403,O43292,Q9NQZ5,O75503,P07602,O95202,P21964,P03886,O60313,Q15125,P13073,Q9UBX3,O60220,Q96N66,Q5H8A4,Q14108,P40855,P51797,O96028 28 +Tremor 0.2761526562376336 1.5410719398153323 0.1232992782536408 1.0 0.6954574987525162 189 P35637,O14653,Q9NZJ7,Q7LG56,O75787,O75027,P00846,O76024,Q9BPX6,Q9H2C2,P07196,Q9Y4P3,P04062,Q9BRK0,Q13510,Q15043,Q9NR77,O43292,P21912,Q06787,Q9NQZ5,O75503,O14773,P07602,Q6DKK2,P03886,Q9NW15,Q96RL7,O60313,Q9BUB7,O60220,P12235,Q10713,Q99720,O00429,Q5HYK3,Q14108,Q9H6K4,Q9Y287 39 +Axial dystonia 0.9231380535244268 1.5406472474437816 0.1234026621893367 1.0 0.6954574987525162 3 Q99720 1 +Extramedullary hematopoiesis 0.7675015800880799 1.5404580632513152 0.1234487375582926 1.0 0.6954574987525162 4 Q14739,Q86WC4 2 +Avascular necrosis 0.4163782412620981 1.5393349788304571 0.1237225387315639 1.0 0.6954574987525162 25 O75844,Q9Y619,Q04656,O00754,P04062,P49327,P02545,P01889,Q9NZ08,Q14108,Q9H173 11 +Inability to walk 0.4128198978314283 1.5384709191160897 0.1239335136859853 1.0 0.6954574987525162 95 Q96D71,P33897,P35637,O14949,Q7LG56,P00846,Q9NVI7,Q9H9S5,P07196,Q13510,Q15043,Q9NR77,O43292,P21912,O75503,Q9UID3,Q96CU9,P30153,Q96RL7,Q7RTS9,O60220,P12235,Q96N66,Q99720,O00429,O15269 26 +Abnormality of the gastric mucosa 0.4839728502802773 1.5377194746998193 0.1241172198423599 1.0 0.6954574987525162 16 Q9Y4P3,Q6PGP7,P04062,P49327,Q14739,O76024 6 +Shuffling gait 0.4983349806301532 1.5375793936680506 0.1241514890361634 1.0 0.6954574987525162 14 O75844,P04062,O60220,P02545 4 +Hyperventilation 0.6196802943575255 1.535358739823291 0.1246957328243842 1.0 0.6976666301652751 7 P00846 1 +Arthralgia 0.3879169242079662 1.5328277051757466 0.1253183123988783 1.0 0.6981959158789434 40 Q9Y4P3,Q03252,Q96HY6,Q13510,P28070,P02545,P01889,O15460,Q9NZ08,P22413,P06280,Q15800 12 +Protruding tongue 0.4905640986490033 1.5318743021950638 0.1255534560404876 1.0 0.6981959158789434 15 Q6NUK1,Q9C0B1,Q05086,Q10713,Q96RL7,P20700,O60826 7 +Respiratory arrest 0.5771581870683902 1.5317804022372852 0.1255766337510659 1.0 0.6981959158789434 9 P23786,P13473,Q14203 3 +Blurred vision 0.7147614722199929 1.5282117484475306 0.1264599727794784 1.0 0.7007990158196096 5 P03886,P00846 2 +Abnormal social behavior 0.4113946976158174 1.5273730120955051 0.1266682833980368 1.0 0.7011187386657092 71 Q86Y39,Q5KU26,Q9NZJ7,Q9UHX1,Q01082,O43676,P05067,Q5XKP0,Q9Y4P3,Q9NPL8,Q06787,P07602,O96008,Q96CU9,O75746,Q8N183,O43681,P03886,Q9GZY8,Q15125,Q96RR1,Q9Y6M9,O96000,Q15233,P35250,Q15067,Q9P0J0,Q9NX14 28 +Neurofibrillary tangles 0.6680953878597318 1.5252472309584575 0.1271974441220837 1.0 0.7023773456563464 6 P61916,P05067,Q9Y287,O15118 4 +Disproportionate short trunk short stature 0.6676913365759896 1.5233028884384996 0.1276829448513889 1.0 0.7033894772582434 6 P16278,Q7RTS9,Q9UHX1 3 +Limb girdle muscle weakness 0.4070088233794494 1.5169281311226983 0.1292848302464511 1.0 0.7087191183317725 29 Q8TD16,O14979,Q9NZJ7,Q7LG56,Q13126,P02545,O60313,P07602,Q9H9S5,P12235 10 +Emg myopathic abnormalities 0.3926862095428592 1.515823835668823 0.1295639032653788 1.0 0.7087191183317725 35 Q8WXH0,P07196,P51114,P50402,Q9BTV4,P50570,P13473,Q13586,Q7LG56,P22626,P02545,Q96RR1,Q9H9S5,P12235 14 +Wide anterior fontanel 0.4121227022240104 1.514471013378274 0.1299064202209958 1.0 0.7089265956960559 26 P16435,O75381,Q32P28,Q15125,Q16134,Q9Y487,P40855,P42345 8 +Spastic paraparesis 0.4226443569883042 1.512576115882124 0.1303873648150677 1.0 0.7107180131313119 24 Q9Y619,P33897,Q6DKK2,P04062,Q9H6K4,O75787,P21912,Q5XKP0 8 +Deep palmar crease 0.5283463810298371 1.5114934280037051 0.1306627817671917 1.0 0.7112451584817019 12 Q6NUK1,P61978,O00170,P98175,Q9Y487,P42345 6 +Impaired vibration sensation at ankles 0.91508066766312 1.5091432007483898 0.1312621915907126 1.0 0.7127100458158604 3 P33897 1 +Alveolar ridge overgrowth 0.9041443473357732 1.506327451621753 0.1319831343805795 1.0 0.7127100458158604 2 Q15392 1 +Sensory ataxia 0.7096583932309014 1.505127229766888 0.1322913695438952 1.0 0.7127100458158604 5 Q9NR77,Q13217,P54802 3 +Heart block 0.4110515472022539 1.50457322504355 0.132433834318395 1.0 0.7127100458158604 26 Q8WXH0,P23786,P36543,P50402,Q7LG56,Q07954,P02545,Q9HD47,P06280,Q9H490 10 +Joint subluxation 0.6636824805070811 1.5039994292756471 0.132581513689995 1.0 0.7127100458158604 6 Q9UHX1 1 +Weak cry 0.5700254039725199 1.5035653416807493 0.1326933207012373 1.0 0.7127100458158604 10 Q13510,O60313 2 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.6135533511782859 1.5033717666180928 0.1327432029478734 1.0 0.7127100458158604 7 Q8WXH0,P02545,P50402 3 +Accessory spleen 0.5714420524090531 1.4994078496157968 0.1337678584584671 1.0 0.7134626831097016 9 Q15904,O95202,Q96J42 3 +Amyloidosis 0.7578163288153273 1.4988803718138062 0.1339046692533998 1.0 0.7134626831097016 4 Q9Y287 1 +Atlantoaxial instability 0.902170848604458 1.4980913163888447 0.1341095269003194 1.0 0.7134626831097016 2 Q9NWM8 1 +Abnormality of the glenoid fossa 0.9021708486044576 1.4980913163888432 0.1341095269003198 1.0 0.7134626831097016 2 Q9Y619 1 +Aortic regurgitation 0.4068489868785001 1.4972729345816294 0.1343222543552868 1.0 0.7137786461459594 28 O75844,P36543,O00754,Q96PU5,P49327,Q9UHX1,P02545,P01889,Q01082,Q9NZ08,Q6ZXV5 11 +Hyperconvex nail 0.5791525524320452 1.4915686452301025 0.135812263087427 1.0 0.7167869440725314 8 P51812,Q9Y619,P42892,O95202 4 +Elevated circulating alanine aminotransferase concentration 0.5082160119902907 1.4882455633889853 0.1366861452277024 1.0 0.7194852726370979 13 P10253,Q15904,Q96RL7 3 +Abnormal aortic valve physiology 0.3893577684013418 1.4871849919287838 0.1369659587769347 1.0 0.7194852726370979 45 O75844,Q9Y4P3,P36543,O00754,Q96PU5,P04062,Q9UHX1,P02545,Q15125,P01889,Q9NZ08,Q6ZXV5,Q12768,P16278 14 +Posterior fossa cyst 0.7546247579642841 1.4851620492996456 0.1375009024536759 1.0 0.7198730200165775 4 Q9H9S5,Q9UHX1 2 +Generalized onset motor seizure 0.4012171197774812 1.4826771680296942 0.1381602036052727 1.0 0.7213836287608234 59 Q9Y619,Q96N66,Q01105,P04062,Q9NZJ7,Q13510,P03886,O00429,Q5HYK3,P21912,P00846,P07602,P16278 13 +Decreased facial expression 0.3944522149298995 1.48094961070998 0.1386200015173662 1.0 0.7219557408930195 33 Q04656,Q6P1N0,Q969X5,Q7LG56,P04062,Q15043,O75787,Q96RR1,Q14203,Q06787,Q9H9S5,P12235 12 +Abnormality of the posterior pituitary 0.5767989226533773 1.478509563511092 0.1392714392254279 1.0 0.7219557408930195 8 Q9UHX1,O76024 2 +Abnormality of krebs cycle metabolism 0.7034205235952056 1.4768710967191137 0.1397101939857643 1.0 0.7219557408930195 5 P00846 1 +Color vision defect 0.4826188389542769 1.4761362136650933 0.1399073289374977 1.0 0.7220272906918533 15 Q6P4Q7,O60313,Q9H6K4,Q9H061,O60220 5 +Generalized hyperpigmentation 0.5226120121529468 1.4753331684310032 0.140122993291738 1.0 0.7223394615426807 12 P51648 1 +Abnormal placenta morphology 0.5757819039681737 1.472863550357678 0.1407878321881912 1.0 0.7230895129337771 8 O75844,Q01082,P16278,P02545 4 +Head titubation 0.6070122237150584 1.4691531995609466 0.1417912409065898 1.0 0.7245205558948139 7 Q99720,P20700,Q96RL7,P35637 4 +Talipes calcaneovalgus 0.6066220454847848 1.467109903486441 0.1423461605007261 1.0 0.7257627350831107 7 Q9NR77 1 +Abnormality of the distal phalanges of the toes 0.7009029345372234 1.4654557146347564 0.1427966263141113 1.0 0.726058698296479 5 O75844,Q71SY5,Q7LGA3,P02545 4 +Butterfly vertebrae 0.749506346967557 1.4631451666960145 0.1434276611004392 1.0 0.726058698296479 4 Q8WTW3,Q8N3U4,O75845 3 +Hypolipoproteinemia 0.5736712559544928 1.4611403778766774 0.1439769212015407 1.0 0.726058698296479 8 Q15800,Q9UJS0,P37268,P02545 4 +Oligosacchariduria 0.6997496198468044 1.4602242209267158 0.1442284606902202 1.0 0.726058698296479 5 P10253,P16278 2 +Abdominal distention 0.4039856530013984 1.453913388466305 0.1459703204243851 1.0 0.7275073250273159 27 Q96HY6,Q9NZJ7,Q7LG56,P04062,Q15643,Q7RTS9,Q01844,P07602 8 +Mitral valve calcification 0.7458646982507047 1.4474690276706192 0.1477656049530245 1.0 0.7317218112497033 4 O75844,P04062 2 +Cardiac valve calcification 0.7458646982507047 1.4474690276706192 0.1477656049530245 1.0 0.7317218112497033 4 O75844,P04062 2 +Abnormal cry 0.5018653906203124 1.446477191355653 0.1480434048865289 1.0 0.7317218112497033 13 Q13510,O60313 2 +Absent epiphyses 0.6506974339573361 1.4413284038182 0.1494919264987972 1.0 0.7343112277646213 6 Q7LGA3 1 +Chronic pulmonary obstruction 0.569834006516822 1.4398075374085986 0.1499218581175001 1.0 0.7343112277646213 8 P09601,P21964 2 +Gastric ulcer 0.8968430613293299 1.4377565137987407 0.1505031518807702 1.0 0.7343112277646213 3 P04062 1 +Hypoplastic labia majora 0.5377333021582518 1.436265142434918 0.150926908822425 1.0 0.7343112277646213 11 Q9Y619,P16435 2 +Abnormal labia majora morphology 0.5377333021582518 1.436265142434918 0.150926908822425 1.0 0.7343112277646213 11 Q9Y619,P16435 2 +Ectrodactyly 0.4457487839398283 1.436061390310089 0.1509848732999255 1.0 0.7343112277646213 20 P07196,Q99720,Q5H8A4,Q9NR77,O95202 5 +Enlarged ovaries 0.7428711420490098 1.4345760061070332 0.1514079559721126 1.0 0.7343112277646213 4 P21912,P16435 2 +Punctate cataract 0.8959167337208759 1.4341285264422303 0.1515355886633727 1.0 0.7343112277646213 3 Q9H6K4 1 +Retinal thinning 0.8866647871440538 1.433370112457165 0.1517520949334541 1.0 0.7343112277646213 2 P51648 1 +Adrenal insufficiency 0.396267531259243 1.4328169982015355 0.1519101422851407 1.0 0.7343112277646213 30 P16435,P33897,O75381,O95470,Q13423,P40855 6 +Abnormality of the tarsal bones 0.3958536119041937 1.42880197646892 0.1530611573480627 1.0 0.7368145682060309 30 O75844,P16435,Q9UPT5,Q969X5,Q15058,Q9UHX1,P02545,Q15125,O75787,Q14739,P98175,Q7RTS9 12 +Upper limb muscle weakness 0.399035082411598 1.4232927110832654 0.154651319083753 1.0 0.7414102420544161 28 Q8WXH0,P07196,P50402,Q9BTV4,Q969X5,Q969G3,P02545,P00846,Q8N0X7 9 +Recurrent aspiration pneumonia 0.6466521233437129 1.4217623237584895 0.1550952605025721 1.0 0.7414102420544161 6 Q6NUK1,P04062,Q13510 3 +Aplasia hypoplasia involving the vertebral column 0.4747567996126656 1.4208079968217706 0.1553725852648246 1.0 0.7414102420544161 15 Q96HY6,Q8TAA9,Q14739,Q7RTS9,P16278 5 +Microcytic anemia 0.5351614250666623 1.420757628805536 0.1553872325224039 1.0 0.7414102420544161 11 P22830,Q9BQT8,Q9UBX3 3 +Abnormal labia minora morphology 0.566321356750138 1.420258033174122 0.1555325740656099 1.0 0.7414102420544161 8 Q9Y619 1 +Supernumerary spleens 0.5555001140503656 1.420036148553555 0.1555971574576897 1.0 0.7414102420544161 10 Q15904,O95202,Q96J42 3 +Abnormality of extrapyramidal motor function 0.4042922980507369 1.419468900632349 0.1557623573987641 1.0 0.7414102420544161 81 Q96IX5,P35637,Q9NZJ7,O14949,Q7LG56,O75787,P05067,Q9BPX6,P16278,Q9Y4P3,P17900,P04062,Q15043,Q9UBB4,P06865,Q06787,P07602,Q6DKK2,Q96RL7,O75569,Q96RR1,P98175,P12235,Q99720,Q9H6K4 25 +Pedal edema 0.5661762704936639 1.4194501406827724 0.1557678231426893 1.0 0.7414102420544161 8 Q14108 1 +Vitiligo 0.5658256628546019 1.4174976961002808 0.156337467469487 1.0 0.7426029704800636 8 P03886 1 +Flaring of rib cage 0.891475127166393 1.416731022528015 0.1565615833493421 1.0 0.7426369257499761 3 P16278 1 +Corneal dystrophy 0.6895741598720391 1.4140149804652191 0.1573575040548194 1.0 0.7426369257499761 5 P06280,P12235 2 +Abnormality of facial adipose tissue 0.7378915517483129 1.413116858554818 0.1576213670981507 1.0 0.7426369257499761 4 O75844,Q03252 2 +Aplasia hypoplasia of the capital femoral epiphysis 0.689374163692196 1.4131058548458078 0.1576246020019591 1.0 0.7426369257499761 5 Q7LGA3 1 +Abnormal macular morphology 0.3920915949733844 1.4121983538461564 0.1578915650802397 1.0 0.7426369257499761 31 P51648,P04062,Q9NW15,Q13510,P50897,P04439,P22413,Q86YV9 8 +Neck muscle weakness 0.4590959887935601 1.4121896222340828 0.1578941353548084 1.0 0.7426369257499761 17 P35637,Q9NZJ7,Q7LG56,Q99720,P02545,P07602 6 +Cardiac arrest 0.3771100279980573 1.411930034346348 0.1579705632306862 1.0 0.7426369257499761 37 Q8WXH0,Q9Y4P3,P50402,P04062,P02545,P01889,Q99758,P50416,O15460,P22413,Q9HD47 11 +Poor motor coordination 0.4799012870734935 1.411089983576727 0.1582180830740176 1.0 0.7426369257499761 14 O75503,Q96RL7,Q06787,Q9H9S5 4 +Pulmonary embolism 0.737373434800215 1.4108832371217683 0.1582790456537588 1.0 0.7426369257499761 4 P01889,Q9NZ08 2 +Retinal detachment 0.454095210323062 1.4106064531642937 0.158360687782018 1.0 0.7426369257499761 18 Q13045,P98164,Q8NCH0,P04439,O43505,Q9H9S5 6 +Aplasia hypoplasia of toe 0.3739697975906014 1.409701290410294 0.158627903556525 1.0 0.7428701117259798 38 Q9NX62,Q5JRA6,Q03164,Q13510,Q9UHX1,Q5H8A4,P13073,Q7LGA3,O96028,O95202 10 +Ureteral duplication 0.5549987831635201 1.4059408776874152 0.1597416815586385 1.0 0.7443674696378564 9 O75844,P23786,Q96J42 3 +Bradycardia 0.4790188623377928 1.4050133436176813 0.1600173104197604 1.0 0.7443674696378564 14 O75880,O75208,Q9BTV4,P02545,Q99758,Q96RR1,P51970 7 +Hypoplasia of the iris 0.5634261412202286 1.4041303222059267 0.1602800457328352 1.0 0.7443674696378564 8 Q13586,O95202,Q7LGA3 3 +Dysmetria 0.3982217887479402 1.4025316630200226 0.1607565422249324 1.0 0.7443674696378564 66 Q96D71,P33897,Q7LG56,O75787,O75027,Q96TA2,Q9Y4P3,O15020,Q9UBB4,O43292,Q9NPL8,Q06787,O14773,O75503,Q8IV08,Q8N183,Q6DKK2,Q9NW15,O60313,Q5JRX3,Q9NP80,Q8N0X7,Q10713,Q6P4A7,Q5HYK3,P20700,P35250,Q6PJG6,Q12768 29 +Cerebellar cortical atrophy 0.7348525795648867 1.400013623736455 0.1615092388113845 1.0 0.7443674696378564 4 O75312,O75845 2 +Cranial asymmetry 0.6416141837603726 1.397370109861121 0.162302302697695 1.0 0.7443674696378564 6 O95202,P40855 2 +Proximal muscle weakness 0.3995666839968686 1.3970692869921164 0.1623927365640056 1.0 0.7443674696378564 70 Q8WXH0,Q8TD16,P35637,P13473,Q7LG56,P02545,P00846,Q9BPX6,Q9H9S5,P07196,Q8TB36,Q13126,Q13510,P21912,P51114,P50402,P10253,Q9BTV4,O60313,Q9NP80,Q9BQT8,P12235,Q13586,Q99720 24 +Acute coronary syndrome 0.433636085783033 1.3967747332667415 0.1624813226245622 1.0 0.7443674696378564 21 O75844,Q9Y4P3,P02545,P01889,Q9NZ08,P22413,P06280 7 +Astrocytosis 0.5533279236564564 1.3964177375527145 0.1625887367726655 1.0 0.7443674696378564 9 P00846 1 +Elevated gamma glutamyltransferase level 0.7337709640325275 1.395348795385927 0.1629106842617851 1.0 0.7443674696378564 4 Q5XKP0 1 +Loss of subcutaneous adipose tissue in limbs 0.7336962203095873 1.3950264158551726 0.1630078738843874 1.0 0.7443674696378564 4 O75844,Q03252 2 +Short lingual frenulum 0.7326800003941621 1.3906430456870245 0.1643336963287069 1.0 0.7443674696378564 4 O75844 1 +Hydrocele testis 0.6400244244371116 1.3896675194668986 0.1646298622576003 1.0 0.7443674696378564 6 Q9UBX3 1 +Ventriculomegaly 0.2728567070519713 1.3892434554005355 0.1647587317135095 1.0 0.7443674696378564 201 P23786,P36543,Q8TD16,Q13045,Q5KU26,Q9NZJ7,Q9UHX1,P00846,Q15392,Q86WC4,P16278,Q9H9S5,Q01105,P04062,Q9NPL8,Q6ZXV5,P07602,O95202,Q9UID3,P51812,Q96CU9,P30153,Q9HC21,Q8NCH0,Q96RL7,Q15125,O43505,Q9UP83,Q96J42,Q9Y487,P42345,Q03252,Q16625,Q10713,O00584,Q969G3,Q9Y320,O96028 38 +Abnormal abdomen morphology 0.2839022099081659 1.3870999360251253 0.1654112915390089 1.0 0.7443674696378564 245 P23786,O75381,Q86Y39,P09601,Q9NZJ7,Q9UJW0,P00846,Q9NZ08,O43676,P00374,Q15392,Q9HC07,P16278,Q9NVI7,Q86WC4,Q96A33,P04062,P54802,Q13510,Q16134,Q9NPL8,O15118,Q01844,P07602,Q96CU9,P21964,P10253,O75845,O00754,P03886,Q96I36,Q96RL7,Q9HC21,Q9BT22,Q9BUB7,Q9UP83,Q9NWS8,O96000,P10619,Q9Y619,P08236,Q16625,Q96HY6,Q15904,Q14108,Q14739,P40855,P15586,Q96AA3 49 +Dysphagia 0.3514237775221079 1.385716555202954 0.1658334709897537 1.0 0.7443674696378564 147 Q96D71,P33897,Q9UEY8,P35637,P61916,Q03164,Q9NZJ7,Q7LG56,Q9UHX1,Q8IZA0,P00846,O76024,P05067,P55011,Q9HD42,Q01105,O43819,P04062,Q9P0J1,Q13510,Q9UBB4,Q9NR77,P21912,Q06787,O94905,O15118,P07602,Q05086,Q8N183,P03886,Q96RL7,O75569,O60313,Q96RR1,Q14203,Q8N0X7,O60220,P12235,Q04656,Q99720,O00429,Q15067,P20700,P01889,Q14108,Q14739,P15586 47 +Papule 0.4393213904821687 1.3846734883000855 0.1661523292447895 1.0 0.7443674696378564 20 O75844,P16615,P49327,P02545,P01889,P21912,Q9NZ08,P38435 8 +Visual loss 0.3923578973534575 1.3843743636795427 0.1662438545668316 1.0 0.7443674696378564 59 P33897,Q9NZJ7,Q01082,P50897,P04439,P00846,P98164,P00403,O14773,O75503,P07602,Q15051,P03886,O60313,P53701,O60220,Q10713,Q969G3,O00429,P01889,O15460 21 +Abnormal pulmonary interstitial morphology 0.3866303483429871 1.37952295199194 0.1677335746301109 1.0 0.7443674696378564 32 P09601,P04062,Q13510,Q8IZA0,Q14108 5 +Obsessive compulsive trait 0.6818707348951629 1.3789750820909288 0.1679024367604187 1.0 0.7443674696378564 5 O75503 1 +Pericardial effusion 0.558473258772931 1.3765118871127362 0.1686632096508449 1.0 0.7454548303738412 8 P04062,Q14108,P22413 3 +Broad palm 0.558400834028737 1.37610777495611 0.168788268789265 1.0 0.7454548303738412 8 P51812,Q14739 2 +Slowly progressive 0.394134341784239 1.375214013199968 0.1690651051225393 1.0 0.7459697292373656 63 Q9H3H5,O43707,P33993,P50570,P02545,O75787,Q8N2K0,Q5JTV8,P05023,P07196,O15020,Q9BRK0,Q92734,Q9NR77,O94905,O14773,Q8IV08,P50402,O95140,O14979,Q9BTV4,Q14203,Q9Y4W6,P12235,Q6PI48,Q04656,Q13586,O00584,Q99720,O00429,Q96BR5,Q9P0J0,Q15120 33 +Progressive inability to walk 0.4152688245638856 1.372799395385542 0.1698147187796828 1.0 0.7478595231025765 23 Q7LG56,Q96RL7,Q15043,P21912,P00846,Q9H9S5 6 +Bilateral coxa valga 0.8717225824640464 1.3710214401480358 0.1703682725571496 1.0 0.7494412913682154 2 Q96A33 1 +Abnormal lumbar spine morphology 0.5264336394010918 1.3680469281154175 0.1712973873630665 1.0 0.7520710797182286 11 P51812,P04062,O00754,O75845 4 +Abnormal renal tubule morphology 0.3957844010876156 1.36293408506976 0.1729032852732783 1.0 0.7535069234465249 26 P23786,P03886,P00846 3 +Aspiration 0.5255470372818688 1.3626855663794473 0.1729816286471424 1.0 0.7535069234465249 11 P17900 1 +Reduced brain n acetyl aspartate level by mrs 0.877469561207532 1.3618617647316713 0.1732415148058055 1.0 0.7535069234465249 3 P07602 1 +Abnormal brain choline level by mrs 0.877469561207532 1.3618617647316713 0.1732415148058055 1.0 0.7535069234465249 3 P07602 1 +Abnormal brain n acetyl aspartate level by mrs 0.877469561207532 1.3618617647316713 0.1732415148058055 1.0 0.7535069234465249 3 P07602 1 +Waddling gait 0.3924723470857921 1.360948644021691 0.1735299195040707 1.0 0.7535069234465249 28 Q8WXH0,Q9H3H5,P07196,Q8TD16,P50402,Q9BTV4,P22626,Q13510,P02545,Q7RTS9,Q9H9S5 11 +Infectious encephalitis 0.5449267840759295 1.3590116552602085 0.1741428954148012 1.0 0.7538466708351901 10 P01889,Q9NZ08,Q14739,Q9BUB7 4 +Prominent ear helix 0.7252548935042338 1.3586010290168908 0.1742730489420758 1.0 0.7538466708351901 4 O75844 1 +Upper airway obstruction 0.6767529831287844 1.3556732719834093 0.1752031471836348 1.0 0.7538466708351901 5 O75844,P16435,Q96HY6 3 +Temperature instability 0.5461554947718459 1.3554914980927155 0.1752610155220659 1.0 0.7538466708351901 9 Q9HC21,Q9NZJ7,P07602 3 +Dysesthesia 0.5852962480249655 1.3551030231103538 0.1753847356636972 1.0 0.7538466708351901 7 Q9NR77,P33897,Q8NCH0 3 +Abnormal talus morphology 0.4354164139508715 1.3533953959985945 0.1759293475031724 1.0 0.7540986304118488 20 O75844,P16435,Q9UPT5,Q969X5,Q9UHX1,P02545,P98175 7 +Limb myoclonus 0.6758242091993593 1.3514426724106603 0.1765536721783622 1.0 0.756078513330521 5 Q13510 1 +Abnormality of the supraorbital ridges 0.4044861392598675 1.350837164705047 0.1767476000722831 1.0 0.7562133072945572 24 P51812,Q6NUK1,P16435,O75381,Q15022,P98175,P40855 7 +Abnormal pleura morphology 0.3938842088727479 1.3452401625303194 0.1785476901794487 1.0 0.7606466731398064 26 Q6NUK1,P08236,P36543,Q8NCH0,P01889,O15460,Q9NZ08,Q14739,Q9UID3 9 +Abnormal sharpey fiber morphology 0.583392299757358 1.345075608164905 0.1786008192785839 1.0 0.7606466731398064 7 Q04656,P02545,P01889,P22413,P29992 5 +Poor head control 0.3967801249906432 1.3423017223359408 0.1794981852139059 1.0 0.7617721860293111 76 Q86Y39,Q5KU26,Q9NZJ7,O43676,O95721,P00374,Q5XKP0,Q9H2C2,P17900,P21912,P06865,Q9NPL8,P07602,Q96CU9,P03886,P13073,Q9NWM8,O96000,Q9P0J0 19 +Optic nerve hypoplasia 0.4269635689180975 1.3419453154567864 0.1796137271883218 1.0 0.7617721860293111 21 P07196,P61978,O75312,P30153,Q15058,Q9UHX1,Q9NVI7,Q9H9S5,P37268 9 +Lower limb pain 0.6736924924765135 1.3417307242744736 0.1796833212159363 1.0 0.7617721860293111 5 O95140,P00846,O75569 3 +Urinary bladder sphincter dysfunction 0.5415737351289645 1.3396265917120975 0.1803667741128578 1.0 0.7625861339648985 10 Q9NR77,Q9BRK0,P33897,Q06787 4 +Prelingual sensorineural hearing impairment 0.8710972351761562 1.336898348610322 0.1812558199563647 1.0 0.7642625379500706 3 O60220 1 +Childhood onset sensorineural hearing impairment 0.8710972351761562 1.336898348610322 0.1812558199563647 1.0 0.7642625379500706 3 O60220 1 +Obstructive sleep apnea 0.5002605958669054 1.33373920777532 0.1822893404778747 1.0 0.7645188868330367 12 P51114,Q15233,Q96A33,P51530,Q96KP1 5 +Impaired visuospatial constructive cognition 0.5507736806579786 1.333512448272727 0.1823636931580505 1.0 0.7645188868330367 8 P03886,P33897,P00403 3 +Aplasia hypoplasia of the 5th finger 0.4847080962104787 1.3331990643346492 0.182466486331241 1.0 0.7645188868330367 13 Q9UHX1 1 +Limb girdle muscle atrophy 0.4683595152053271 1.3314811119481536 0.1830307558881507 1.0 0.7645188868330367 14 Q8WXH0,P50402,O14979,P02545,Q9H9S5 5 +Hypercholesterolemia 0.4998135643164837 1.3308985134388736 0.1832224064618604 1.0 0.7645188868330367 12 Q8N511,Q13045 2 +Hemianopia 0.5501276793843699 1.3299015114932826 0.1835507233630342 1.0 0.7645188868330367 8 P03886,P00403 2 +Abnormality of chorioretinal pigmentation 0.6710418010719381 1.3296508878358309 0.1836333232836959 1.0 0.7645188868330367 5 Q5XKP0 1 +Morning glory anomaly 0.8615731604172494 1.3287077901313296 0.18394439382449 1.0 0.7645188868330367 2 O60313 1 +Temporal optic disc pallor 0.8615731604172494 1.3287077901313296 0.18394439382449 1.0 0.7645188868330367 2 O60313 1 +Telangiectasia 0.3662825725110341 1.3268352748093266 0.1845631789220523 1.0 0.7657233492710817 38 P03886,Q8IZA0,P00846,Q14739,P10619 5 +Functional motor deficit 0.3323406134854492 1.3259471014424429 0.1848572198114517 1.0 0.7662603367963561 156 P23786,Q9Y2R0,P33897,Q8TD16,P35637,O14653,P13473,Q9NZJ7,Q7LG56,O75787,P00846,Q9BPX6,Q9H9S5,Q9H2C2,P07196,Q53H12,P04062,Q13510,Q9H2D1,P00403,Q9NR77,O43292,P21912,Q07021,O14773,P07602,Q9HC21,P03886,Q96RL7,Q9NWM8,Q7RTS9,Q8N0X7,P12235,Q13586,Q99720,Q969G3,O00429,Q15067,P20700,P46020 40 +Basal ganglia calcification 0.5405634220468879 1.3235353842690674 0.1856573972032924 1.0 0.7675268063777321 9 P03886,P00403,O60313 3 +Spastic diplegia 0.4012749754275132 1.3221123406722386 0.1861307450199123 1.0 0.7681080668783191 24 Q99720,P07602,P51648,P35637 4 +Ovarian cyst 0.4540385382550008 1.321614827539655 0.1862964433656613 1.0 0.7681080668783191 16 Q9Y4P3,P16435,Q03252,P02545,P21912,P10644 6 +Irregular menstruation 0.6690305548831578 1.3204827772010577 0.1866738825461886 1.0 0.7681080668783191 5 P10644,Q06787,P02545 3 +Abnormal saccadic eye movements 0.3880644937289484 1.3189831840150412 0.1871747343656424 1.0 0.7681080668783191 28 Q10713,P04062,Q9NW15,Q96RL7,Q5HYK3,O14773,Q8IV08 7 +Juvenile onset 0.3738261885950679 1.3186592302261135 0.1872830624934247 1.0 0.7681080668783191 45 P07196,Q03252,Q04656,Q6P1N0,O15118,P50570,P50402,P54802,Q13510,P02545,Q9NR77,O75027,P06280,O14773,P16278,P51798 16 +Erythema 0.3906047085802782 1.3146745570054374 0.1886193010037276 1.0 0.7722276571436693 26 P22830,P51648,Q06136,P03886,P00403 5 +Muscle weakness 0.2957675875652766 1.312356338797649 0.1893999312094643 1.0 0.7724399390700818 317 Q9UHX1,P00846,Q5JTV8,O43676,Q96TA2,P00374,Q9HC07,P17900,Q13126,Q13510,Q16134,P07602,Q96CU9,P10253,O14979,P03886,P13073,Q8N0X7,Q15067,Q70HW3,P20700,Q9P0J0,P01889,O15460,Q12768,Q8WXH0,P23786,P33897,Q86Y39,Q969X5,P02545,Q9NP58,O00400,Q5XKP0,P05023,Q9H2C2,Q8TB36,P00403,Q9NR77,P51812,Q6DKK2,Q9BTV4,Q8NCH0,O43681,Q96RL7,O60313,Q96RR1,O43505,Q14203,Q9Y6M9,Q9NWM8,P51970,Q9H173,P12235,Q13586,Q99720,Q14739,P40855,P35637,Q5KU26,Q9NZJ7,P07196,P06865,Q9NPL8,P51114,P50402,Q9BQT8,Q7RTS9,O96000,O15269,P46020,O75381,Q8TD16,P13473,Q7LG56,O95721,Q9BPX6,Q9H9S5,Q53H12,Q92804,Q15043,P21912,Q06787,Q15165,Q9HC21,Q9NP80,Q6NUK1,Q10713,Q969G3 89 +Reduced subcutaneous adipose tissue 0.5384508072431407 1.3114531945791077 0.1897046970861922 1.0 0.7725943700229437 9 Q6NUK1,O75844,P36543 3 +Photoreceptor layer loss on macular oct 0.856498449393856 1.307568361404925 0.1910197539404929 1.0 0.7752371007785481 2 P04439 1 +Abnormal optical coherence tomography 0.856498449393856 1.307568361404925 0.1910197539404929 1.0 0.7752371007785481 2 P04439 1 +Hypermetric saccades 0.8632052232889944 1.3059895352847546 0.1915561163120118 1.0 0.7760606800978374 3 O14773 1 +Abnormal femoral neck morphology 0.3713554110897614 1.3037943051299623 0.1923037248536152 1.0 0.7767213638223702 44 P51812,O75844,Q9Y619,Q8WTW3,Q04656,Q96HY6,O00754,Q96A33,Q15643,Q9H173,P55011,P02545,P22413,P04066,Q9Y487,Q7RTS9,P16278,Q96AY3 18 +Concentric hypertrophic cardiomyopathy 0.8623738796023839 1.3027343633689568 0.1926654660252964 1.0 0.7771730886895624 3 P03886 1 +Anomalous trichromacy 0.861816130851657 1.3005505653829963 0.193412337464933 1.0 0.7787859515788074 3 Q9H6K4,O60313 2 +Tritanomaly 0.861816130851657 1.3005505653829963 0.193412337464933 1.0 0.7787859515788074 3 Q9H6K4,O60313 2 +Arthritis 0.3741241066856555 1.2986721710552775 0.1940564584054671 1.0 0.7787859515788074 47 O75844,Q96HY6,P21964,P04062,Q13510,P28070,P02545,Q96RL7,P10321,P01889,O15460,Q9NZ08,Q14739,Q14108,P06280 15 +Cerebral inclusion bodies 0.4508051746515309 1.2981482111187723 0.1942364102648754 1.0 0.7787859515788074 16 P05067,P04062,Q9Y287 3 +Visual field defect 0.3750323748547989 1.297385022781026 0.1944987431909268 1.0 0.7791666519395564 48 O75381,P03886,Q969G3,P00403,O00429,O60313,P01889,P04439,P00846,P40855,Q9Y287,Q9H6K4,Q9H061,O60220 14 +Hypoglycemic seizures 0.5741526173063052 1.2963626235864023 0.1948505826946602 1.0 0.7792349333708278 7 Q16836,Q13423 2 +Thoracic kyphoscoliosis 0.6194974772970352 1.2900159592698226 0.1970451170263305 1.0 0.7833006146520655 6 O75844 1 +Abnormality of the temporomandibular joint 0.7091976656980745 1.289244996642659 0.1973129263311697 1.0 0.783676916499383 4 O75844,Q96RL7 2 +Paroxysmal involuntary eye movements 0.427363100870141 1.288774533797732 0.1974764818590282 1.0 0.783676916499383 20 Q96CU9,Q86Y39,P03886,Q9NPL8,O43676 5 +Paranoia 0.5726123961941938 1.288235069429286 0.1976641477264249 1.0 0.7837534988641466 7 Q96RL7 1 +Degeneration of the lateral corticospinal tracts 0.5723482415845418 1.2868409737383368 0.1981497222895165 1.0 0.7843426507293363 7 O00400,Q12768,P35637 3 +Abnormal response to endocrine stimulation test 0.8578508660828537 1.2850275462709695 0.1987826582434309 1.0 0.7856860763432414 3 Q13423 1 +Abnormality of bladder morphology 0.5126116248205447 1.2843450793701812 0.1990212402818241 1.0 0.7856860763432414 11 Q9NWM8,Q9Y4P3,P16435,Q04656 4 +Stillbirth 0.4769617506356673 1.281890252558589 0.1998811477857311 1.0 0.7856860763432414 13 O75844,P16435,P04062,Q14739,Q86WC4 5 +Abnormal posturing 0.8502960248096939 1.2817514232379563 0.1999298595996927 1.0 0.7856860763432414 2 O60220 1 +Peripheral axonal degeneration 0.3919713760917696 1.280781708886135 0.2002703504355045 1.0 0.7856860763432414 78 P07196,P12235,P33897,Q6DKK2,P03886,Q9NZJ7,P00403,Q96RL7,O60313,O15269,Q7LG56,P00846,Q9NVI7,O76024,Q9BPX6,Q9BQT8,P07602,Q8IV08 18 +Pseudoepiphyses of the metacarpals 0.706740369873593 1.2786268230225917 0.2010284997144369 1.0 0.7857159245765776 4 P51812,O95202 2 +Pseudoepiphyses of hand bones 0.706740369873593 1.2786268230225917 0.2010284997144369 1.0 0.7857159245765776 4 P51812,O95202 2 +Hyperextensible skin 0.4316611773697915 1.277909603994801 0.2012813013469938 1.0 0.7860440081965238 19 P04062,Q9UHX1,Q8NCH0 3 +Abnormality of the larynx 0.3730692792472089 1.2758934396130457 0.2019931904680163 1.0 0.7866737394464108 48 P16435,Q96HY6,P35637,P21964,Q92804,Q9NZJ7,Q13510,Q9UHX1,Q14739,P07602,Q15165 11 +Myoclonic spasms 0.6164221721635712 1.2750613361533225 0.2022875330005056 1.0 0.7866737394464108 6 Q969G3,Q10713,P00846 3 +Genu varum 0.4905358793917983 1.271884842967812 0.2034140379451499 1.0 0.7869264714308374 12 Q9Y619,Q15643,Q96HY6,Q7RTS9 4 +Malrotation of small bowel 0.7051505085010672 1.2717566682815349 0.2034595892240709 1.0 0.7869264714308374 4 Q8NCH0,O95202 2 +Abnormal circulating fatty acid concentration 0.4249438224852725 1.269336370620605 0.2043211196564474 1.0 0.7886524145943306 20 P23786,P33897,O75381,Q16836,P40855 5 +Abnormal sternal ossification 0.7041771179854249 1.267550372771355 0.2049585640146023 1.0 0.7896648087203442 4 Q9Y619,O95202 2 +Progressive pes cavus 0.704090512377214 1.267176124299457 0.2050923208899884 1.0 0.7896648087203442 4 O00400 1 +Pendular nystagmus 0.5682437076662115 1.2651725427625875 0.2058094828159511 1.0 0.7907768442556613 7 P00846 1 +Vertebral compression fracture 0.4393034223572776 1.2649457652546272 0.2058907701907328 1.0 0.7907768442556613 17 Q96HY6,P04062,Q32P28,Q14108,Q96AY3 5 +Abnormal placental size 0.7025959826138921 1.26071780796801 0.2074105356124738 1.0 0.7928176827756018 4 O75844,P02545 2 +Psychotic mentation 0.613454334523367 1.2606248939926457 0.207444025267601 1.0 0.7928176827756018 6 P03886 1 +Arterial thrombosis 0.566924169195158 1.2582041338762666 0.2083179403393522 1.0 0.7948524690817087 7 P01889,O15460,Q9NZ08 3 +Facial myokymia 0.8440936002255295 1.255960800943284 0.2091301825296492 1.0 0.7967822840907501 2 P33897 1 +Pelvic kidney 0.5286211510769296 1.2551792578473222 0.2094136935248505 1.0 0.7967822840907501 9 Q9Y4P3,Q9BXW9,Q9UHX1 3 +Bifid scrotum 0.6123235344214546 1.255123340106644 0.2094339887968019 1.0 0.7967822840907501 6 Q01082,Q96EK5,P16435 3 +Loss of ability to walk 0.4446203558853214 1.2532158294803022 0.2101271706605914 1.0 0.7978319571166826 16 P21912,Q7LG56,P00846,Q9H9S5 4 +Abnormal larynx physiology 0.4509030139882364 1.2521137348040168 0.2105284236188875 1.0 0.7982804248522972 15 Q92804,Q13510,P35637 3 +Vegetative state 0.654006843823411 1.2519495097457924 0.2105882624529798 1.0 0.7982804248522972 5 P33897,P07602 2 +Abnormal hdl cholesterol concentration 0.7000793984282723 1.2498429712996286 0.2113569152605527 1.0 0.7985753990620403 4 Q9UJS0,P02545 2 +Progeroid facial appearance 0.5357533579342628 1.2494491277557371 0.2115008492460113 1.0 0.7985753990620403 8 O75844,Q03252 2 +Aplasia involving bones of the extremities 0.6996687816027177 1.248068613209678 0.2120059313011966 1.0 0.7985753990620403 4 Q04656,P02545 2 +Abnormal greater sciatic notch morphology 0.6103427220110187 1.2454851326243996 0.2129534771726566 1.0 0.7985753990620403 6 Q7RTS9,Q96HY6 2 +Abnormal visual electrophysiology 0.3759148684658592 1.2453027520529414 0.2130204844458183 1.0 0.7985753990620403 54 O14773,O60313,P50897,P00846,O75503,P07602,O60220,P12235 8 +Action tremor 0.3836988749873787 1.244506783128298 0.2133131044541356 1.0 0.7985753990620403 65 P35637,Q9NZJ7,O75787,O75027,P00846,O15020,Q9BRK0,Q9UBB4,Q9NR77,Q06787,O14773,P07602,O43681,P03886,Q96RL7,Q9NW15,O75569,Q9BUB7,Q99720,P20700,Q14108,Q6PJG6,Q9H6K4,Q9Y287 24 +Abnormal calcification of the carpal bones 0.8412743163236591 1.2442477363988151 0.2134083996820179 1.0 0.7985753990620403 2 Q15125 1 +Angioid streaks of the fundus 0.8412743163236551 1.2442477363987985 0.2134083996820241 1.0 0.7985753990620403 2 P38435 1 +Muscle hypertrophy of the lower extremities 0.5343395610236318 1.2415274165199084 0.2144109765237851 1.0 0.7985753990620403 8 Q9NR77,Q9H9S5,P02545 3 +Focal dystonia 0.3839943764610065 1.2415167076748714 0.2144149299799349 1.0 0.7985753990620403 25 P35637,Q99720,Q96RL7,Q9NQZ5,O60220 5 +Recurrent pancreatitis 0.8465942401749311 1.240991229643695 0.2146089888040325 1.0 0.7985753990620403 3 P03886 1 +Abnormal metabolic brain imaging by mrs 0.4360389349122203 1.240593337669702 0.2147560143643887 1.0 0.7985753990620403 17 Q9NZJ7,P03886,P00403,P21912,P07602 5 +Abnormal circulating copper concentration 0.6092991385651981 1.2404067282066962 0.2148249936659478 1.0 0.7985753990620403 6 Q15904,Q9Y487 2 +Nemaline bodies 0.6972174996433576 1.2374764150250115 0.2159102650020494 1.0 0.8002831237187628 4 O43676 1 +Deep plantar creases 0.6500500788489024 1.2338910650275698 0.2172434994084202 1.0 0.8032315248182654 5 P61978,P42345,Q9Y487 3 +Retinopathy 0.371851902345595 1.2319420671265005 0.2179707257189445 1.0 0.8052807366838783 32 P51648,Q5JRA6,Q5H8A4,P01889,Q9NZ08,P00846,P22413,O96028,O95202 9 +Slow saccadic eye movements 0.4841385014064909 1.2311406739818154 0.2182702553151772 1.0 0.8053519129395569 12 P04062,Q96RL7,Q8IV08 3 +Pathologic fracture 0.4347486886929286 1.2309648598879792 0.2183360073318412 1.0 0.8053519129395569 17 O15269,P04062,Q14108,O75845 4 +Anophthalmia 0.4537540579068205 1.2304252432672098 0.2185379052924938 1.0 0.8053935129708168 14 P52732,O75569,O43505,Q96J42,P53701,Q9H9S5,Q9NX14 7 +Infantile axial hypotonia 0.5035280053488552 1.2292294555369294 0.2189857880333232 1.0 0.8053935129708168 11 Q9NZJ7,P07602,Q15043,P17900 4 +Emg chronic denervation signs 0.4411115429754758 1.2277032035252446 0.2195584034285642 1.0 0.8053935129708168 16 O43819,Q9NZJ7,Q969X5,Q13510,O43681,O60313,P07602 7 +Abnormal electroretinogram 0.3645039750516618 1.224323201028794 0.2208303279807686 1.0 0.8078272796101572 35 Q96S66,Q53H12,Q04837,Q15067,P50897,P00846,O14773,O60220,P12235 9 +Status epilepticus with prominent motor symptoms 0.6940669514647737 1.2238637027731736 0.2210036482946353 1.0 0.8078272796101572 4 Q13510 1 +Arm dystonia 0.6477828786960139 1.2235430906097382 0.2211246392540233 1.0 0.8078272796101572 5 Q99720 1 +Skin dimple 0.3707583428074575 1.2209948148149694 0.2220879830325675 1.0 0.8086226961191596 32 Q9Y4P3,P61978,Q8TAA9,Q03164,Q969X5,Q5H8A4,P35250,Q15125,Q8N6M0,Q9NX14,Q9UM00,P53701,O96028,O95202,P62258 15 +Atrial arrhythmia 0.501814808553457 1.2188281625936543 0.2229094200138899 1.0 0.8104117561216423 11 P50402,Q9BTV4,Q7LG56,P02545,P12235 5 +Retinal vascular tortuosity 0.4330423738150302 1.2182288490537212 0.2231370195570354 1.0 0.8104117561216423 17 P03886,P00846 2 +Nephropathy 0.3895775323258197 1.2172592330740684 0.2235055998161248 1.0 0.8104117561216423 24 P03886,Q14108,P00403,O76024 4 +Brushfield spots 0.6917271571425778 1.2137551826065076 0.2248412251289118 1.0 0.8119061139216318 4 P40855 1 +Parkinsonism with favorable response to dopaminergic medication 0.5009090774921702 1.2133286245389827 0.2250042031222805 1.0 0.8119061139216318 11 P04062,P07602 2 +Bilateral tonic clonic seizure with focal onset 0.8392452335142112 1.2122740398029164 0.2254074977926898 1.0 0.8119061139216318 3 P07602 1 +Caudate atrophy 0.8389471746154262 1.2111099927518374 0.2258532521143703 1.0 0.8119061139216318 3 Q96RL7 1 +Stuttering 0.8388203978345738 1.2106148920702426 0.2260430340800074 1.0 0.8119061139216318 3 P03886 1 +Elevated serum acid phosphatase 0.6904040493324217 1.2080395554718055 0.2270320477271679 1.0 0.8142019893451206 4 P07602 1 +Sclerocornea 0.4503298022349188 1.2066996005148058 0.2275478529973407 1.0 0.8147963505404777 14 Q6NUK1,Q5H8A4,O75569,Q96J42,O96028,O95202 6 +Echolalia 0.4652559666367931 1.2042305999157816 0.2285004619062229 1.0 0.8175785166590837 13 Q9UJS0,Q9UHX1,Q01082,O75787,P53701,Q9NX14 6 +Abnormal pupillary light reflex 0.6892294825020476 1.2029659822876788 0.2289894848163114 1.0 0.8178538484805179 4 Q9NR77,P07602 2 +Slow pupillary light response 0.6892294825020476 1.2029659822876788 0.2289894848163114 1.0 0.8178538484805179 4 Q9NR77,P07602 2 +Joint hemorrhage 0.8305610374964756 1.1998044624244706 0.2302152906940469 1.0 0.819932806565255 2 P38435 1 +Abnormality of the spinocerebellar tracts 0.8349843841393253 1.1956390242194517 0.2318374558220064 1.0 0.8231909663245156 3 Q7LG56 1 +Athetosis 0.4296719318347059 1.1930644785816602 0.2328441217201704 1.0 0.8240827189334853 17 Q96CU9,O14949 2 +Abnormal lung lobation 0.4422953238301174 1.191042159370726 0.2336370346502589 1.0 0.824549201134917 15 Q9UHX1,P21964 2 +Sepsis 0.394226809918166 1.1896771841447913 0.2341732962834517 1.0 0.8251577036635683 23 P02786,P33897,P01889,Q99758,Q9BT22,P42892 6 +Abnormal patella morphology 0.3727532157826724 1.1874687061943128 0.2350427931719423 1.0 0.8263914312965595 29 Q9Y619,Q9NX62,P21964,Q96PU5,Q15125,Q6ZXV5 6 +Abnormality of the mitochondrion 0.3818360683773877 1.1863728849941388 0.2354750748878977 1.0 0.8263914312965595 103 P23786,Q9Y2R0,Q86Y39,P35637,Q7LG56,P00846,O43676,Q9Y584,Q9P0J1,P00403,P21912,Q16134,Q9NPL8,Q96CU9,Q16836,P03886,P13073,Q9UBX3,Q9BUB7,O96000,P12235,O00429,Q70HW3,Q9P0J0,Q7KZN9 25 +Abnormal protein o linked glycosylation 0.8319664471940746 1.1838640249438033 0.2364668929080595 1.0 0.8263914312965595 3 Q8N511 1 +Genu valgum 0.3566126283900823 1.1814555873524089 0.2374217867261887 1.0 0.827316759569613 41 Q9Y619,Q9Y4P3,P08236,O75312,Q9NX62,Q04656,O00754,Q8N0X7,Q01082,Q9NR77,P22413,Q9UP83,Q7LGA3,Q7RTS9,P16278 15 +Poor wound healing 0.5966727535524909 1.178944493052298 0.2384202791810805 1.0 0.827316759569613 6 P04062 1 +Periventricular heterotopia 0.4950227774676644 1.1775802365573689 0.2389639926758924 1.0 0.827316759569613 11 Q96PU5,Q06787,Q6ZXV5 3 +Severe short stature 0.3731521442119955 1.1766105179359214 0.2393509977666392 1.0 0.827316759569613 28 Q9Y619,Q96HY6,P21912,Q7RTS9,Q15392,P16278,P10619 7 +Extra axial cerebrospinal fluid accumulation 0.8246405413025117 1.175295599110558 0.2398764745924113 1.0 0.827316759569613 2 Q03252 1 +Abnormality of hepatobiliary system physiology 0.3840719701512137 1.1752110728875949 0.2399102813348397 1.0 0.827316759569613 86 P23786,O75381,O75787,P00846,Q5XKP0,Q86WC4,Q8N511,Q96A33,P04062,Q13510,O15118,Q9UID3,P22830,Q16836,O75845,P03886,P50416,Q9BT22,Q9NWS8,Q9Y619,Q16625,Q10713,P01889,P40855 24 +Abnormality of visual evoked potentials 0.3767301189489887 1.1742991642855924 0.2402752179327543 1.0 0.827316759569613 25 O75503,P07602,O60220,O60313 4 +Enthesitis 0.8243586129123206 1.17412954094491 0.240343142603685 1.0 0.827316759569613 2 P22413 1 +Abnormal sacroiliac joint morphology 0.8243586129123206 1.17412954094491 0.240343142603685 1.0 0.827316759569613 2 P22413 1 +Zonular cataract 0.5129045972216134 1.1734588566501327 0.2406118467027118 1.0 0.827316759569613 10 Q9H6K4,P08670 2 +Gastrointestinal infarctions 0.8237947561319413 1.1717977179776868 0.2412782791191774 1.0 0.827316759569613 2 P01889 1 +Glossitis 0.8237947561319413 1.1717977179776868 0.2412782791191774 1.0 0.827316759569613 2 P01889 1 +Male hypogonadism 0.5139449843752033 1.171043412781678 0.2415813275532126 1.0 0.8274915965858753 9 P33897 1 +Orofacial dyskinesia 0.5213767607668633 1.168854879547548 0.2424621050715705 1.0 0.8289385375128467 8 Q9BPX6,Q96RL7 2 +Ichthyosis 0.3541889891789679 1.1684448480731002 0.2426273735546253 1.0 0.8289385375128467 40 O75381,P51648,P50402,O95470,Q13586,P04062,Q15125,P40855,Q15800 9 +Neurogenic bladder 0.4934825404529736 1.168224915178708 0.2427160529817422 1.0 0.8289385375128467 11 P51797,O76024,Q8TAA9 3 +Myotonia 0.520921915578503 1.166304209655129 0.2434914717902476 1.0 0.8309771269674507 8 Q8WXH0,P02545,P50402 3 +Constriction of peripheral visual field 0.3913098365282947 1.1642352823388145 0.2443286755387399 1.0 0.8311279388899311 23 O60313,P00846,P40855,Q9H061,O60220 5 +Postaxial polydactyly 0.391137497994613 1.1627319737627324 0.2449382647339024 1.0 0.8311279388899311 23 Q9Y366,P30153,Q10713,O75845,Q15125,Q14739,P98175,Q96J42,Q9UM00 9 +Easy fatigability 0.3834998011089448 1.1626914336816885 0.2449547184365119 1.0 0.8311279388899311 24 Q9H3H5,P12235,P61978,Q53H12,P50570,Q13586,Q7LG56,P21912,Q96RR1,Q9NWM8,P10644 11 +Limb pain 0.5122671926396044 1.1614210169617976 0.2454707260844939 1.0 0.8312723867203581 9 O15269,P00846 2 +Thoracic hypoplasia 0.3605130959398966 1.1595041306188354 0.246250753806529 1.0 0.8312723867203581 34 Q9Y366,P16435,Q04656,Q96HY6,Q96A33,P04062,Q15643,Q9UHX1,P02545,Q14739,Q9UM00,P42345 12 +Proximal muscle weakness in lower limbs 0.4046426031084319 1.1578651027925075 0.2469190905953922 1.0 0.8312723867203581 21 Q8WXH0,P07196,P50402,Q9BTV4,Q7LG56,P02545,Q96RR1,P12235 8 +Calcinosis 0.6333831902128996 1.157829142153718 0.2469337682852064 1.0 0.8312723867203581 5 O75844,Q14739 2 +Hyporeflexia of upper limbs 0.8251551043429273 1.1573140547901335 0.2471440733513765 1.0 0.8312723867203581 3 Q9NR77,O75787 2 +Spastic tetraparesis 0.3736674191135064 1.1564058068322685 0.2475152075178366 1.0 0.8312723867203581 26 P33897,P17900,Q9NZJ7,P00846,Q7RTS9,P07602 6 +Phenotypic variability 0.3771298128900379 1.1556247889339146 0.2478346639935338 1.0 0.8312723867203581 108 Q8TD16,Q9NZJ7,P00846,P00374,Q9H9S5,P07196,P17900,O95470,Q53H12,Q13510,P00403,Q9NR77,P21912,Q06787,Q92733,P07602,P03886,O60313,Q15125,Q9NWS8,Q9H061,Q13586,Q969G3,O00429,Q70HW3 25 +Psoriasiform dermatitis 0.8245910885504814 1.15511730107508 0.2480423942329919 1.0 0.8312723867203581 3 P10321,Q15800 2 +Aplasia hypoplasia of the spleen 0.5911148941301162 1.151888511154492 0.2493668898799781 1.0 0.8347548462367497 6 Q96J42 1 +Aplasia hypoplasia of the optic nerve 0.3730580442762909 1.150703918741812 0.2498540638162412 1.0 0.8347548462367497 26 P07196,P61978,O75312,P30153,Q15058,Q9UHX1,Q8N3U4,O95721,Q9NVI7,Q9H9S5,P37268 11 +Metaphyseal cupping 0.6770098730606775 1.1502131438141618 0.2500560939496126 1.0 0.8347548462367497 4 Q15643,Q14739,O95831 3 +Abnormality of the intrahepatic bile duct 0.6770098730606593 1.1502131438140826 0.2500560939496452 1.0 0.8347548462367497 4 Q9Y5L0,Q10713,P02545 3 +Pneumothorax 0.5098195643453315 1.1473834784893076 0.2512231663826068 1.0 0.8353170282221676 9 Q6NUK1,Q8NCH0 2 +Decreased light and dark adapted electroretinogram amplitude 0.8224607733312759 1.1468226083725008 0.2514549432923831 1.0 0.8354909072277257 3 P50897 1 +Broad phalanx of the toes 0.5165880241662772 1.1420009857176707 0.2534536099529298 1.0 0.8388169985322954 8 Q9H936,Q71SY5,P98172,O14936,Q7LGA3 5 +Delayed cranial suture closure 0.3627338752460374 1.1405978928834888 0.2540372945207738 1.0 0.8388169985322954 32 P51812,O75844,P16435,O75381,Q8NCH0,Q32P28,P40855,Q9Y487 8 +Abnormal cardiac test 0.402533464600298 1.1404444450344071 0.2541011853058921 1.0 0.8388169985322954 21 Q9H3H5,Q16836,P10253,Q9BTV4,Q7LG56,Q969Y2,Q96RR1,Q9HD47,P12235 9 +Exercise induced muscle stiffness 0.8161826895968486 1.1403584532688005 0.2541369944204554 1.0 0.8388169985322954 2 P46020 1 +Ketotic hypoglycemia 0.8161826895968243 1.1403584532687 0.2541369944204974 1.0 0.8388169985322954 2 Q13423 1 +Sclerosis of hand bone 0.815618832816466 1.1380327678433884 0.2551067998624443 1.0 0.8388169985322954 2 Q15125 1 +Stiff skin 0.815618832816447 1.1380327678433098 0.2551067998624772 1.0 0.8388169985322954 2 O75844 1 +Aplasia hypoplasia of the colon 0.815618832816447 1.1380327678433098 0.2551067998624772 1.0 0.8388169985322954 2 O75844 1 +Prominent umbilicus 0.815618832816447 1.1380327678433098 0.2551067998624772 1.0 0.8388169985322954 2 O75844 1 +Epidermal hyperkeratosis 0.815618832816447 1.1380327678433098 0.2551067998624772 1.0 0.8388169985322954 2 O75844 1 +Abnormally lax or hyperextensible skin 0.3612083304642591 1.1345835505079256 0.2565498485524364 1.0 0.8388169985322954 49 P51812,Q6NUK1,Q9Y4P3,P36543,P04062,Q8NCH0,Q9UHX1,O75787,Q15904,P22413,Q9Y487,Q9NWM8,O96000,P38435 14 +Abnormality of the dorsal column of the spinal cord 0.6731146365933355 1.1334129015461798 0.2570408986810633 1.0 0.8388169985322954 4 P33897,Q6PI48 2 +Brisk reflexes 0.3719125441686712 1.1296933816643482 0.258605446969578 1.0 0.8388169985322954 25 Q10713,P35637,P20674,Q99720,Q9NW15,Q9BSJ2,Q5HYK3,Q01082,Q9UP83,Q8NI60 10 +Bladder diverticulum 0.5062976400807102 1.1271859590795712 0.2596638657110715 1.0 0.8388169985322954 9 Q9NWM8,Q9Y4P3,Q04656 3 +Postaxial hand polydactyly 0.4533909651676829 1.125448836048042 0.2603988865379696 1.0 0.8400255140916484 13 Q96J42,Q14739,O75845 3 +Abnormal gastrointestinal motility 0.3662079891260664 1.1241653253274106 0.2609428964863247 1.0 0.8405625926733874 29 P35637,P03886,Q7LG56,P00403,O76024,P06280 6 +Absent nipple 0.8122356921342017 1.1240884051537772 0.2609755236838635 1.0 0.8405625926733874 2 Q6NUK1 1 +Abnormal central sensory function 0.6258826883742865 1.123623216747534 0.2611729025787996 1.0 0.8405625926733874 5 P33897,Q969G3 2 +Mitral stenosis 0.8158488437676119 1.121105551463767 0.2622429359199858 1.0 0.8413100390816912 3 O75844,P04062 2 +Aortic valve calcification 0.8158488437676119 1.121105551463767 0.2622429359199858 1.0 0.8413100390816912 3 O75844,P04062 2 +Abnormal gallbladder morphology 0.354463292734798 1.1197943381172322 0.2628014125829925 1.0 0.8419412082407639 35 P22830,P21964,Q96A33,P04062,P40855,P07602 6 +Hypertrophic nerve changes 0.8102621934028602 1.1159621735377938 0.2644383264990146 1.0 0.846020900242552 2 Q9NR77 1 +Dysdiadochokinesis 0.4154132802636701 1.115409953527115 0.2646747861279594 1.0 0.8461958306494858 18 Q6DKK2,O15020,P20700,O75027,Q06787,O75503 6 +Disproportionate tall stature 0.3596307276994375 1.109488865193051 0.2672193453018381 1.0 0.8510840821571376 32 P16435,O00754,Q8NCH0,Q5H8A4,Q7LGA3,Q9NWM8,O96028,O95202 8 +Abnormality of somatosensory evoked potentials 0.5384154044351617 1.1075261602087103 0.2680665083069087 1.0 0.85235628153597 7 Q9NQZ5,P33897 2 +Myokymia 0.8121143109870352 1.1066000593192058 0.26846688165082 1.0 0.8524647572200322 3 P33897 1 +Proximal muscle weakness in upper limbs 0.4300025777820641 1.1037784467747451 0.2696892565731215 1.0 0.8528174406848484 15 Q8WXH0,P07196,P50402,Q9BTV4,P02545 5 +Vaginal atresia 0.8071609811107998 1.103204825925436 0.2699382260712251 1.0 0.8528174406848484 2 P16435 1 +Impaired temperature sensation 0.5811023392443786 1.1031664620314288 0.2699548828309226 1.0 0.8528174406848484 6 Q9NR77,O15269,P07686 3 +Ambiguous genitalia male 0.8099543341627555 1.0982174964535745 0.2721095279395078 1.0 0.8528174406848484 3 Q15392 1 +Short middle phalanx of finger 0.8097243801365959 1.0973253964142375 0.2724991728575614 1.0 0.8528174406848484 3 Q9UHX1 1 +Upper limb postural tremor 0.6646784361098197 1.0970639505792474 0.2726134375593367 1.0 0.8528174406848484 4 Q9NR77 1 +Rimmed vacuoles 0.4167989658832867 1.0969204494866611 0.2726761685348564 1.0 0.8528174406848484 17 Q8WXH0,P50402,Q9BTV4,O14979,P02545,Q9Y5L0,P22626,Q9H173 8 +Severe postnatal growth retardation 0.4630017200785638 1.0964180592418142 0.2728958643916224 1.0 0.8528174406848484 12 O95202,O76024 2 +Right ventricular hypertrophy 0.619074492099314 1.0926010253399678 0.2745690123448432 1.0 0.8528174406848484 5 Q969Y2,Q9H267,Q9H9C1,Q15233 4 +Laryngomalacia 0.4283861678258805 1.0923069177597613 0.2746982207219521 1.0 0.8528174406848484 15 P16435,P36543,P21964,Q9NZJ7,P07602 5 +Abnormal liver physiology 0.5351324657087978 1.0901805117077068 0.2756336362026184 1.0 0.8528174406848484 7 Q13510,O75845 2 +Aplasia hypoplasia of the patella 0.5782913345815968 1.0894960184821076 0.2759352096752521 1.0 0.8528174406848484 6 Q9Y619 1 +Orchitis 0.8076706147772231 1.08936066733355 0.2759948692166536 1.0 0.8528174406848484 3 P01889,Q9NZ08 2 +Pleuritis 0.8076706147772231 1.08936066733355 0.2759948692166536 1.0 0.8528174406848484 3 P01889,Q9NZ08 2 +Skeletal dysplasia 0.3560237281262638 1.088852180427054 0.2762190766609662 1.0 0.8528174406848484 48 P07237,O75381,P51648,Q96HY6,Q14739,P40855,Q7RTS9,Q9HC07,P16278,P10619 10 +Abnormal corneal epithelium morphology 0.4073586783419975 1.087440382579277 0.2768422325671484 1.0 0.8528174406848484 19 O75844,P51648,P02545,P01889,Q9NZ08,Q14739 6 +Abnormal visual field test 0.6179006686144775 1.087255646709948 0.2769238442861341 1.0 0.8528174406848484 5 P00846 1 +Progressive spastic paraplegia 0.3623462680222675 1.086808534244708 0.2771214353239419 1.0 0.8528174406848484 29 Q9P0J0,Q96CU9,P00846,Q7KZN9 4 +Abnormality of the alveolar ridges 0.5341175691066438 1.08481943320945 0.2780016367264835 1.0 0.8528174406848484 7 Q15392 1 +Distal peripheral sensory neuropathy 0.6172745287807138 1.0844047613407173 0.278185373559334 1.0 0.8528174406848484 5 P03886 1 +Aplasia hypoplasia of the lungs 0.3463840633940739 1.084045739247473 0.278344519298237 1.0 0.8528174406848484 37 O75844,Q8TAA9,Q15643,Q5H8A4,Q14739,P98175,Q16134,O96028,O95202,O96000 10 +Lethal skeletal dysplasia 0.8062075358013462 1.0836898200454443 0.2785023507513036 1.0 0.8528174406848484 3 Q14739 1 +Transient ischemic attack 0.5059214502521706 1.0822073672436991 0.2791603956264885 1.0 0.8528174406848484 8 O75844,P06280,P22413 3 +Gowers sign 0.421086515281984 1.0819913336910478 0.2792563787978244 1.0 0.8528174406848484 16 P07196,Q13510,Q8TD16 3 +Falls 0.4792333650911318 1.081697365739661 0.2793870240696872 1.0 0.8528174406848484 11 P21912,O75787,Q9BQT8,Q96RL7 4 +Abnormal joint morphology 0.283396214541463 1.0794209362802625 0.2804001219380638 1.0 0.8547888458557218 304 P36543,Q03164,Q9UHX1,O75787,Q5JTV8,P37268,Q9Y4P3,Q9Y584,Q13510,P22413,Q6ZXV5,P07602,P49902,Q15022,P49257,Q8N0X7,O75844,Q8WTW3,Q5JRA6,Q86XL3,P01889,O15460,Q14108,Q7LGA3,Q9H6K4,Q8WXH0,P23786,P33897,Q969X5,P28070,P02545,Q8IZA0,Q9NZ08,Q15392,P16278,Q9HD42,Q8WVM7,Q96A33,P04062,Q9NR77,Q9NX62,P21964,Q96PU5,Q8NCH0,Q96RL7,P42892,O60220,Q9Y619,Q96HY6,Q14739,Q9NZJ7,P06280,P38435,P07196,O95202,O75312,P50402,P51571,Q9NW15,Q15125,Q9BUB7,Q7RTS9,P16435,Q8TAA9,Q96AY3,O15269,O96028,Q8TD16,Q9H9S5,Q15043,P10321,P21912,O00754,Q15643,Q9UP83,Q9Y487,P08236,Q03252 78 +Abnormal pupil morphology 0.446256308006876 1.0780919950009662 0.2809927036517727 1.0 0.8555941328812773 13 Q13586,Q9NR77,O95202 3 +Abnormality of the wrist 0.3525152611253102 1.0772763372829204 0.2813568303483658 1.0 0.8555941328812773 34 O75844,P16435,Q969X5,Q15643,Q13510,Q15125,P22413,Q9H6K4,Q7RTS9,P16278 10 +Inappropriate behavior 0.405728474361714 1.074663230708929 0.2825255314656507 1.0 0.8557452965661715 19 P07602,Q96RL7,P17900 3 +Dysmetric saccades 0.5321432945678799 1.074392448973036 0.2826468253870162 1.0 0.8557452965661715 7 O14773,Q9NW15 2 +Heterogeneous 0.3574534215030877 1.0714933186286788 0.2839476733032708 1.0 0.8582963761212506 51 Q9BQE5,P61916,P50570,P02545,P00846,P05067,P07196,Q8TB36,Q9NR77,Q15051,Q16836,P21964,P03886,P11717,Q14203,P12235,O75844,Q9Y619,P01889 19 +Abnormal form of the vertebral bodies 0.3750755481145534 1.0707778029325334 0.2842693498385356 1.0 0.8587111119392493 94 Q9Y2W2,Q12768,Q13045,Q32P28,Q9UHX1,Q9UM00,P16278,P51798,Q9Y4P3,P07237,P54802,P22413,O95202,P10644,P51812,O75845,O00754,Q15643,Q15125,Q7RTS9,Q8WTW3,Q9Y619,O15228,P16435,Q6NUK1,P08236,Q96HY6,Q5JRA6,Q04656,Q8TAA9,Q10713,Q5H8A4,P35250,Q8N3U4,Q14739,P04066,Q96AY3,O96028,P15586 39 +Status epilepticus 0.3573175956514728 1.0699947563387342 0.2846216689946301 1.0 0.8588254520045994 51 Q9H2C2,Q03252,Q01105,Q9NZJ7,O00429,Q13510,P07602,Q9UBB4,O43292,Q96RR1,P42892,Q9Y487,P53701,Q15392,P05023,Q9UID3 16 +Back pain 0.3654515806368878 1.0698736355277727 0.2846761917170992 1.0 0.8588254520045994 25 Q8WXH0,P33897,P50402,Q9BTV4,Q8TAA9,Q969G3,P02545,P01889,Q01082,P51798 10 +Thin ribs 0.4301866148319736 1.0670957870429316 0.2859285840712917 1.0 0.8615296632063482 14 O75844,Q9Y619 2 +Type 2 muscle fiber predominance 0.8010347485221907 1.0636622565239804 0.2874817284714606 1.0 0.8615296632063482 3 P51797 1 +Hyperactive deep tendon reflexes 0.4939729685538111 1.0636370890409936 0.287493133862454 1.0 0.8615296632063482 10 Q9NR77,P21912,O00429,O60220 4 +Abnormal waist to hip ratio 0.5298410028836308 1.062236635397566 0.2881282721593514 1.0 0.8615296632063482 7 Q9Y6M1,P22413,P43304,O76024 4 +Multiple lipomas 0.5023135035213927 1.0619971911510555 0.2882369603424954 1.0 0.8615296632063482 8 O95140,P29992,P22413,Q8TAA9 4 +Quadriceps muscle weakness 0.5721691034915067 1.0597409157824695 0.2892624830964005 1.0 0.8615296632063482 6 Q96RR1,Q7LG56,P12235 3 +Cutis laxa 0.350733132673302 1.0589531677227213 0.2896211086760765 1.0 0.8615296632063482 34 P51812,Q6NUK1,Q9Y4P3,P36543,Q8NCH0,O75787,Q15904,Q9Y487,O96000,P38435 10 +Urinary retention 0.5291214518396583 1.0584383676226878 0.2898556352620502 1.0 0.8615296632063482 7 P33897,Q8TAA9 2 +Short stepped shuffling gait 0.7961657738934137 1.0581077470849327 0.2900063228925651 1.0 0.8615296632063482 2 P04062 1 +Toxemia of pregnancy 0.5716308571576159 1.0571263639718484 0.2904539205087189 1.0 0.8615296632063482 6 Q14739,P02545 2 +Decreased circulating cortisol level 0.4928340529221661 1.0570371321741878 0.2904946411527587 1.0 0.8615296632063482 10 P16435,P33897,Q13423 3 +Progressive peripheral neuropathy 0.7989283699943494 1.0555172772934036 0.2911888119446024 1.0 0.8615296632063482 3 Q9NZJ7,P07602 2 +Neoplasm of the gallbladder 0.7989283699943494 1.0555172772934036 0.2911888119446024 1.0 0.8615296632063482 3 Q9NZJ7,P07602 2 +Biliary tract neoplasm 0.7989283699943494 1.0555172772934036 0.2911888119446024 1.0 0.8615296632063482 3 Q9NZJ7,P07602 2 +Abnormal myelination 0.2664676634831339 1.0552412941500926 0.291314982640344 1.0 0.8615296632063482 232 P33897,Q86Y39,P35637,Q5KU26,Q9NZJ7,Q7LG56,P00846,O43676,O00400,P00374,Q86WC4,Q9H2C2,P07196,P51648,Q9Y584,P00403,Q9NR77,P21912,Q9NPL8,Q6ZXV5,P07602,Q53FT3,Q96CU9,P30153,O75746,P10253,O00754,P03886,Q96I36,Q96RL7,Q9UP83,O96000,O00584,Q99720,Q5H8A4,Q9P0J0,Q7KZN9,Q7LGA3,P40855,O15269 40 +Multicystic kidney dysplasia 0.3982934975228409 1.054887148646594 0.291476940511663 1.0 0.8615296632063482 20 O75381,P40855,Q96J42 3 +Oculomotor apraxia 0.3615781404877434 1.0539111884809735 0.2919235799395718 1.0 0.8615296632063482 27 P33897,Q10713,P04062,O43292,P05067,O14773 6 +Abnormality of cartilage of external ear 0.6543478722726913 1.0526404125629598 0.2925058280425623 1.0 0.8615296632063482 4 Q7LGA3 1 +Retrocollis 0.7978003384094621 1.0511579574301395 0.293186048926866 1.0 0.8616042031278798 3 Q99720,P35637 2 +Ectopic calcification 0.3656235176593947 1.0467912745535537 0.2951958555465106 1.0 0.865724381309696 64 O75844,P23786,P08236,O75381,Q16625,O75845,O00584,P04062,P03886,P00403,O60313,Q15125,Q14739,P40855,P05067,P38435 16 +Abnormal bone structure 0.2574785590810612 1.0451925331283067 0.2959339937800609 1.0 0.8663979503435117 199 O75381,Q9NZJ7,Q32P28,Q7LG56,P06280,Q9H490,Q15392,Q9HC07,P16278,Q86WC4,P38435,Q9Y4P3,P07237,P04062,Q13126,Q13510,P54802,Q15043,O43292,P21912,P22413,P07602,O95202,O75845,O00754,Q9HC21,Q15643,Q15125,Q9UG56,Q9Y487,Q9NWM8,Q7RTS9,P12235,O75844,Q8WTW3,Q9Y619,Q6NUK1,P08236,Q96HY6,Q5JRA6,Q5H8A4,Q14108,Q14739,P40855,Q96AY3,O96028 46 +Abnormality of the ankles 0.354775149626132 1.041946658554125 0.2974364102081688 1.0 0.8674395432053987 51 O75844,Q9Y4P3,P33897,P49902,O00754,Q8N0X7,Q9NZJ7,Q969X5,Q9NW15,Q15043,P02545,O75787,Q5JTV8,Q7RTS9,P07602,O60220,Q96AY3 17 +Abnormality of the auditory canal 0.3840986523952058 1.0416064239158858 0.2975941891512399 1.0 0.8674395432053987 22 O96028,Q9Y619,P16435,O95202 4 +Spastic gait 0.3574140210298188 1.0391095566183852 0.2987537868805547 1.0 0.8699701776645896 29 Q9Y619,P33897,P49902,Q9BRK0,Q15043,P20700,O75787,O00400,Q9NVI7,Q8N0X7 10 +Abnormality of the gallbladder 0.345804060149845 1.0376243744073554 0.2994449655948661 1.0 0.8711019187444999 43 P22830,P21964,Q96A33,Q9NZJ7,P04062,Q5H8A4,O95202,P40855,O96028,P07602 10 +Abnormality of the ischium 0.7942094753852464 1.0372933207899473 0.2995991776390858 1.0 0.8711019187444999 3 Q8IZA0 1 +Calcific stippling 0.650310009720612 1.0353092219307631 0.3005245244627961 1.0 0.8732469796344045 4 Q15125,O15228 2 +Metatarsus valgus 0.793570219966154 1.0348271327793297 0.3007496492009964 1.0 0.873355968203767 3 O43505,Q9H9S5 2 +Protuberant abdomen 0.4970071625620587 1.0322953067463394 0.3019337990174886 1.0 0.87493070957062 8 P42345,P04062,Q15643,Q7RTS9 4 +Tetraparesis 0.3415024367292426 1.031790711270261 0.3021701716078118 1.0 0.87493070957062 37 P33897,P17900,P35637,Q9NZJ7,P00846,Q9UBX3,Q7RTS9,P07602 8 +Vitritis 0.6494027292225877 1.0314178682949346 0.3023449051671605 1.0 0.87493070957062 4 P53701,P04439 2 +Macroorchidism 0.6486899445336798 1.0283614795740834 0.3037798212421578 1.0 0.875944300662091 4 Q06787 1 +Dyslexia 0.4890432179214105 1.028330010091874 0.3037946190554508 1.0 0.875944300662091 9 Q9H6K4 1 +Prominent sternum 0.791109221510836 1.0253387676285526 0.3052033694651852 1.0 0.875944300662091 3 P16278 1 +Vertebral hypoplasia 0.4868680964525393 1.0224882437445166 0.3065498740342121 1.0 0.875944300662091 10 P16278,Q14739,Q96HY6 3 +Cerebral visual impairment 0.3681109804557351 1.021631169225241 0.3069554996052988 1.0 0.875944300662091 73 Q6P1N0,Q7LG56,Q9NZ01,Q9H490,P37268,Q9HD42,Q01105,Q96A33,P00403,Q9UID3,Q96CU9,P30153,P03886,Q96RR1,Q9UP83,O60220,P12235,Q96N66,Q9BSJ2,P20700,P51797 21 +Increased connective tissue 0.494802977700603 1.019966978839196 0.3077441217538479 1.0 0.875944300662091 8 P07196,O75431,P02545,O95831,Q9Y5L0 5 +Peroneal muscle atrophy 0.6030855480840566 1.0199011894600412 0.3077753253794619 1.0 0.875944300662091 5 Q9NR77,Q12768,Q96RL7 3 +Open mouth 0.3506365538127438 1.0193379302924823 0.3080425625330347 1.0 0.875944300662091 32 P51812,P61978,P30153,Q10713,Q86XL3,Q13045,P04062,P42345,P10644 9 +Aplasia of the uterus 0.4946183614183389 1.0189346782177042 0.3082339789228219 1.0 0.875944300662091 8 P30153,O95202 2 +Neonatal death 0.4178910690867686 1.0178907538758304 0.3087298761565962 1.0 0.875944300662091 15 Q6NUK1,P04062,Q14739,Q16134,Q9NVI7,O96000 6 +Gait disturbance 0.2882700028623578 1.016711715844684 0.3092905906801264 1.0 0.875944300662091 346 Q96D71,Q03164,O14949,O75787,P00846,Q9Y4P3,O15020,Q9P0J1,Q13510,O14773,P07602,Q96CU9,P49902,P03886,Q8N0X7,O75844,Q15067,P20700,P01889,Q14108,Q7LGA3,Q9H6K4,Q12768,Q8WXH0,P33897,Q13045,P02545,Q9NZ08,O00400,Q5XKP0,P16278,P05023,Q9H2C2,Q8TB36,P04062,P49327,P00403,Q9UBB4,Q9NR77,O75503,Q8IV08,P51812,Q9BTV4,O43681,Q96RL7,O60313,O75569,Q96RR1,Q14203,O60220,P12235,Q9H173,Q9Y619,Q04656,Q99720,Q8N6M0,P35637,Q9NZJ7,P05067,Q9NVI7,P07196,Q9BRK0,O43292,O15118,Q9UID3,P30153,P50402,P55795,Q9NW15,P98175,Q9BQT8,Q7RTS9,Q96N66,Q5H8A4,Q5HYK3,Q96AY3,O15269,Q8TD16,O14653,P13473,Q7LG56,Q9BPX6,Q9H9S5,Q15043,P21912,Q06787,O00754,Q9HC21,Q9NP80,P42345,Q03252,Q10713,Q969G3,O00429,Q13217 95 +Xerostomia 0.4177058257059723 1.0165787377082305 0.3093538732298873 1.0 0.875944300662091 15 P35637,Q92804,Q9UQN3,Q14739,Q14203,P55011,Q15165 7 +Angiokeratoma 0.7887310234327876 1.0161788490308594 0.3095442265497614 1.0 0.875944300662091 3 P16278 1 +Exaggerated cupid s bow 0.5204561953074697 1.0127376588073929 0.3111854849978799 1.0 0.8766191928562961 7 P11233,Q96KP1,P61978 3 +Abnormal corpus striatum morphology 0.3976741288757623 1.0115866277622472 0.3117357422649878 1.0 0.8766191928562961 19 P00846,Q96RL7 2 +Deformed sella turcica 0.6008046096513395 1.0095535338520067 0.3127092411820573 1.0 0.8766191928562961 5 Q7RTS9 1 +Abnormal iliac wing morphology 0.4167015440889358 1.0094668914011071 0.3127507723052773 1.0 0.8766191928562961 15 P51812,Q7RTS9,P16278,Q8TAA9 4 +Limb dysmetria 0.786909944320674 1.0091710687706914 0.3128925990632916 1.0 0.8766191928562961 3 Q7LG56 1 +Gangrene 0.449182519142003 1.0084669274941451 0.3132303571012704 1.0 0.8766191928562961 12 P49327,Q6UN15,P01889,O15460,P22413,Q9NZ08,P10644 7 +Oral pharyngeal dysphagia 0.4490981337742896 1.0079306959862937 0.313487734172031 1.0 0.8766191928562961 12 Q13510 1 +Difficulty running 0.410830492904278 1.0074543686744148 0.3137164754960302 1.0 0.8766191928562961 16 Q13586,P07196,Q9BPX6,Q8TD16 4 +Vertebral fusion 0.4352369604560489 1.0050546945378755 0.3148705139742451 1.0 0.8776660802213374 13 Q8TAA9,Q9UHX1,O96028,O95202,Q9H9S5 5 +Vocal cord paresis 0.6431593794076212 1.0046708782824334 0.3150553553398987 1.0 0.8776660802213374 4 O95140,Q8TB36,P43243 3 +Moderately reduced visual acuity 0.7857325179040264 1.0046431579749364 0.3150687078722025 1.0 0.8776660802213374 3 O60313 1 +Chronic fatigue 0.5188508495107902 1.0042807142811068 0.3152433267733783 1.0 0.8776660802213374 7 P07602,Q13423 2 +Stenosis of the external auditory canal 0.4915323868080003 1.001686229871904 0.316495159347552 1.0 0.8783733554442231 8 P16435,O95202 2 +Eeg with spike wave complexes 0.4150974871813484 0.998111940699983 0.3182250805853983 1.0 0.8783733554442231 15 Q9NQZ5,Q14108 2 +Femoral bowing 0.482446726008482 0.99691523196609 0.3188056575150633 1.0 0.8783733554442231 10 O00754,P16435,Q32P28,Q7RTS9 4 +Head tremor 0.419683608553398 0.9944360353033852 0.3200106318197584 1.0 0.8783733554442231 14 Q99720,Q96RL7,P35637 3 +Increased csf lactate 0.3532320370218241 0.993929735190496 0.3202570767210972 1.0 0.8783733554442231 54 Q96CU9,Q86Y39,Q9HC21,Q96I36,P03886,P00403,Q9P0J0,P00846,P13073,Q9NPL8,O43676,Q7KZN9,O96000 13 +Aplasia of the phalanges of the hand 0.780095855652666 0.9926324405646518 0.3208891095293849 1.0 0.8783733554442231 2 P02545 1 +Sea blue histiocytosis 0.7817258883248621 0.9892535182374332 0.3225391197218075 1.0 0.8783733554442231 3 O15118,P16278 2 +Abnormal involuntary eye movements 0.2822090338276459 0.9890541236746194 0.322636661579543 1.0 0.8783733554442231 318 Q96D71,O75381,P36543,Q86Y39,P35637,Q5KU26,Q9NZJ7,O75027,P00846,O43676,O76024,O00400,Q5XKP0,Q15392,Q9NVI7,Q86WC4,Q9UGJ1,Q9H2C2,P07196,Q9H490,Q9Y4P3,P17900,Q53H12,O15020,P04062,Q9P0J1,Q13510,Q9NR77,O43292,P21912,Q9NPL8,Q06787,Q86YV9,O14773,O75503,P07602,O95202,Q53FT3,Q8IV08,Q96CU9,P49902,Q6DKK2,O00754,P03886,Q9NW15,O60313,Q15125,Q9BT22,Q9H061,O96000,P12235,Q6NUK1,Q16625,Q6P4Q7,Q10713,O00584,Q99720,O00429,Q5H8A4,Q5HYK3,Q15067,P20700,Q9P0J0,P01889,O96028,Q7KZN9,Q7LGA3,P40855,P51797,Q9H6K4 70 +Aplasia hypoplasia involving bones of the thorax 0.3400983563654363 0.98840944444385 0.3229521639682144 1.0 0.8783733554442231 42 O75844,Q9Y619,P16435,Q96HY6,Q8TAA9,Q03164,Q15643,Q9UHX1,Q14739,P98175,Q7RTS9,Q12768 12 +Hypoplastic female external genitalia 0.4137193383681627 0.9883606360654352 0.3229760587031816 1.0 0.8783733554442231 15 Q9Y619,P16435 2 +Abnormality of thalamus morphology 0.3946291095083585 0.9877721083768826 0.3232642703352983 1.0 0.8783733554442231 19 O43819,Q9UPT5,Q9GZY8,Q969G3,Q969Y2,Q96RR1,Q96KP1,Q9H9S5 8 +Abnormality of the pubic bone 0.4806618584084761 0.9866006630483648 0.3238384450636307 1.0 0.8783733554442231 10 Q8IZA0,O95202,Q5H8A4,Q7RTS9 4 +Redundant neck skin 0.5154478888848605 0.9863659811442452 0.3239535523907717 1.0 0.8783733554442231 7 O96000,Q9Y487 2 +Breast aplasia 0.7806600218031812 0.9851643732814273 0.3245433373402013 1.0 0.8788535400341113 3 Q9Y619 1 +Lower limb amyotrophy 0.3892092686492256 0.9818959876728212 0.3261510926524626 1.0 0.8816686041214946 20 P07196,O00400,Q9NR77,Q9NVI7 4 +Abnormal thorax morphology 0.267629426470108 0.9814333934068744 0.3263790654286533 1.0 0.8817728088046323 250 Q8TD16,Q03164,Q32P28,Q9UHX1,Q9H490,Q9NVI7,P16278,P07196,Q9Y4P3,P07237,P51648,Q96A33,P04062,P54802,Q13510,P21912,Q06787,Q6ZXV5,O95202,P51812,P30153,P21964,P50402,P55795,Q96PU5,Q8NCH0,O75845,O00754,Q15643,O60313,Q15125,P98175,Q9Y487,Q7RTS9,P42345,O75844,Q9Y619,P08236,P16435,Q96HY6,Q8TAA9,O00429,Q5H8A4,Q99758,Q14739,Q7LGA3,Q96AY3,O96028,P15586 49 +Long eyelashes 0.33680727620055 0.9794237030144208 0.3273706701161378 1.0 0.8834440659317654 40 Q6NUK1,Q9Y619,Q8WVM7,P20674,Q5KU26,Q03164,Q969G3,Q9UHX1,Q8N6M0,Q9UID3 10 +Arthrogryposis multiplex congenita 0.3340500667679176 0.9773754989053812 0.3283832881755955 1.0 0.8834440659317654 38 O75844,Q9HD42,Q8TD16,Q9UPT5,Q969X5,P04062,Q8NCH0,P02545,Q96AY3,Q15392,Q96AA3 11 +Abnormality of exocrine pancreas physiology 0.3972591414160158 0.976763901583618 0.3286860511213492 1.0 0.8834440659317654 18 P09601,Q15904,Q9UHX1 3 +Cerebellar atrophy 0.3155003801989549 0.976392941646394 0.3288697779469878 1.0 0.8834440659317654 154 Q96D71,Q7LG56,O75787,P46977,O00400,Q5XKP0,P51572,Q9H490,Q9NVI7,Q13813,P51798,Q9H9S5,Q92643,O15020,Q15043,Q9UBB4,O43292,Q06787,O75503,O14773,Q8IV08,Q96CU9,O75312,O75208,O75845,Q6DKK2,O00754,Q9Y276,Q9GZY8,Q9NW15,O60313,Q96RR1,Q9BT22,P13073,Q13217,Q9UP83,Q8NI60,Q5JRX3,P51970,Q8N0X7,Q9H173,Q8WTW3,P12235,Q6PI48,Q10713,O00429,Q5H8A4,Q5HYK3,Q9Y320,Q14108,Q6PJG6,Q9H6K4 52 +Peptic ulcer 0.4307947445110519 0.9756706387362626 0.3292277067930467 1.0 0.8836898062941669 13 Q9Y4P3,P04062,P35250,O76024 4 +Sagittal craniosynostosis 0.5928329571106034 0.9734483389022108 0.3303305241723833 1.0 0.8836898062941669 5 P21281,P61978,O75419,Q9BZG8 4 +Spinal rigidity 0.4164875906670117 0.9723684040414688 0.3308673046942143 1.0 0.8836898062941669 14 Q8WXH0,P50402,Q9BTV4,P02545,Q5JTV8,O94905 6 +Sclerotic vertebral endplates 0.7750211446292687 0.9720806434151636 0.3310104309804069 1.0 0.8836898062941669 2 P22413 1 +Hip osteoarthritis 0.7750211446292672 0.9720806434151588 0.3310104309804094 1.0 0.8836898062941669 2 P01889 1 +Retinal dysplasia 0.486133630568458 0.971547307435787 0.3312758073354511 1.0 0.8836898062941669 8 Q10713,O43505,P53701,Q9H9S5,Q9NX14 5 +Corneal erosion 0.5539497294014355 0.9714188011220434 0.3313397698385296 1.0 0.8836898062941669 6 P01889,P51648 2 +Increased circulating lactate dehydrogenase concentration 0.3998810368846864 0.970779348596158 0.3316581685228337 1.0 0.8836898062941669 17 P10253,P23786 2 +Metatarsus adductus 0.4159416380774417 0.9686012714401376 0.3327441687556987 1.0 0.8836898062941669 14 Q15392,P08236,O96028,O95202 4 +Aplasia hypoplasia affecting the fundus 0.3486441187826599 0.9678662127099646 0.3331111903760355 1.0 0.8836898062941669 30 P07196,P61978,O75312,P30153,Q15058,Q9UHX1,Q8N3U4,O95721,Q86YV9,Q9NVI7,Q9H9S5,P37268 12 +Patchy alopecia 0.634520596200397 0.9677616987800072 0.3331633963579512 1.0 0.8836898062941669 4 O75844 1 +Abnormal peripheral nervous system physiology 0.3591739857474798 0.9667441372988538 0.3336719567024748 1.0 0.8838722842885266 65 P07196,Q9Y619,P33897,Q9NZJ7,Q7LG56,Q96RL7,Q99720,O60313,Q15125,Q9NR77,Q9NQZ5,O15269,P07602,O60220 14 +Abnormal cornea morphology 0.2755104771978274 0.966082711715416 0.33400279465072 1.0 0.8838722842885266 175 O75381,Q06136,Q13045,Q9NZ08,P06280,Q9NVI7,Q9H9S5,P16278,P51648,Q53H12,P04062,Q13510,O95202,P21964,O00754,O75845,Q8NCH0,Q15125,O43505,Q96J42,Q9NWM8,P12235,O75844,P10619,Q6NUK1,Q16625,Q5H8A4,Q14739,Q7LGA3,P40855,O96028 31 +Talipes valgus 0.5527464023627489 0.9656015348039252 0.3342436070357637 1.0 0.8838722842885266 6 O00754,Q9HD42,Q15233 3 +Dental crowding 0.3510498182201506 0.9653515826474052 0.3343687436031595 1.0 0.8838722842885266 28 O75844,Q96A33,Q01105 3 +Brittle hair 0.4104614142539151 0.9653270017868584 0.3343810514472047 1.0 0.8838722842885266 15 Q6NUK1,O75844,Q6PGP7,Q9Y487,Q9NVI7 5 +Involuntary movements 0.2890937775181806 0.9649670328846652 0.3345613243644219 1.0 0.8838722842885266 365 P33897,Q8TD16,P35637,Q13045,O14653,Q9NZJ7,O14949,Q7LG56,Q9UHX1,P50897,P00846,O76024,P05067,P06280,O00400,P00374,Q5XKP0,Q86WC4,Q9BPX6,Q9H9S5,Q9H2C2,P07196,Q01105,P17900,P04062,Q9BRK0,Q13510,P00403,Q15043,Q9NR77,O43292,P21912,Q9NPL8,Q06787,Q9NQZ5,O14773,O75503,P07602,O95202,Q53FT3,P27544,P51114,Q96CU9,O75845,Q6DKK2,P55795,P03886,Q9NW15,Q96RL7,O60313,P13073,Q9UBX3,Q9BUB7,Q9BQT8,Q9NWS8,O60220,P12235,Q9Y619,Q96N66,Q03252,Q10713,O00584,Q99720,Q969G3,Q5HYK3,Q9P0J0,O96028,Q14108,Q9H6K4,Q9Y287,Q96AA3 71 +Long toe 0.4593625864341912 0.9613555223711276 0.3363734397684017 1.0 0.885525820701654 11 Q9UHX1 1 +Large placenta 0.774111675126896 0.9600896177051188 0.3370101132971677 1.0 0.885525820701654 3 O75844,P02545 2 +Mandibular aplasia 0.5898704367601806 0.9600565315716796 0.3370267640055049 1.0 0.885525820701654 5 Q9Y619,P53701 2 +Macular atrophy 0.4840504230940969 0.9599318239119048 0.3370895283100603 1.0 0.885525820701654 8 P04062 1 +Diminished movement 0.3607569429498082 0.9586224743453616 0.3377489664016653 1.0 0.8859540331284659 24 P13473,P04062,P51114,P12235 4 +Delayed epiphyseal ossification 0.5893418386187147 0.957668672876944 0.3382298584049694 1.0 0.8859540331284659 5 Q96HY6 1 +Dystrophic toenail 0.5508182592644085 0.9562853931618498 0.3389280675435882 1.0 0.8859540331284659 6 O75844,Q969G3 2 +Redundant skin 0.3500568690460042 0.9558823152456244 0.3391316946400171 1.0 0.8859540331284659 28 P51812,Q6NUK1,Q9Y4P3,P36543,Q8NCH0,Q9Y487,O96000,P38435 8 +Brain imaging abnormality 0.3368896340970546 0.953479201454958 0.3403473292583863 1.0 0.8859540331284659 42 P33897,Q9NZJ7,Q9P0J1,P00403,P03886,Q969G3,P21912,Q9BT22,P07602 9 +Abnormal metatarsal morphology 0.3495428813600442 0.950982110729528 0.3416134571721363 1.0 0.8859540331284659 28 P08236,P16435,O43505,O95202,Q7RTS9,O96028,Q15392,Q9H9S5 8 +Breech presentation 0.4754854145359095 0.9509043051613582 0.3416529561641876 1.0 0.8859540331284659 9 Q9Y619,Q969X5,O60313 3 +Abnormality of femur morphology 0.3629801989463161 0.9490109983781656 0.342615018322963 1.0 0.8859540331284659 76 Q9NZJ7,Q32P28,Q9UHX1,P06280,P16278,Q96A33,P04062,P07602,P51812,O00754,Q15643,Q7RTS9,O75844,Q9Y619,P16435,Q96HY6,Q14739,Q7LGA3,Q96AY3 19 +Proportionate short stature 0.3312552427203717 0.947076783993252 0.3435996538428916 1.0 0.8859540331284659 38 Q9Y619,Q16836,Q96HY6,P21912,Q14739,Q7RTS9,Q15392,P16278,P10619 9 +Decreased number of large peripheral myelinated nerve fibers 0.4815687709640727 0.9461062727635612 0.3440943846823729 1.0 0.8859540331284659 8 P07196,O15269,Q7LG56 3 +Mediastinal lymphadenopathy 0.5867615846465277 0.9460201614682684 0.3441383029974421 1.0 0.8859540331284659 5 P01889,Q01844 2 +Paralysis 0.3487681034309202 0.9445169998051004 0.3449055188888401 1.0 0.8859540331284659 54 Q8WXH0,Q8TB36,P35637,P17900,P50402,Q92804,P04062,P10253,Q9HC21,Q9BTV4,P02545,P20700,Q9NP58,Q9NR77,P21912,Q15165 16 +Short ribs 0.4390371554546999 0.9441056447981304 0.3451156650544806 1.0 0.8859540331284659 12 Q9Y619,Q14739,Q96HY6 3 +Small basal ganglia 0.4811557970343848 0.9438068403777514 0.3452683644418015 1.0 0.8859540331284659 8 P00846 1 +Abnormal large intestine physiology 0.3659725447241981 0.9434780694310276 0.3454364275248476 1.0 0.8859540331284659 23 P33897,P21964,Q8TAA9,Q9NZJ7,P06280,P07602 6 +Coarse hair 0.3841894933496437 0.9416537049020756 0.3463699643476139 1.0 0.8873704920408051 20 P51812,Q6NUK1,P36543,Q04656,Q96A33,P54802,Q9Y487,Q9UM00,P15586 9 +Distal lower limb muscle weakness 0.3783305571408785 0.9408598872871602 0.3467766661306211 1.0 0.887533105230542 21 Q9NR77,P33897,P00846 3 +Decreased number of peripheral myelinated nerve fibers 0.3840810852925837 0.9407855599905796 0.3468147622802053 1.0 0.887533105230542 20 P07196,Q8TB36,P50570,Q7LG56,Q92734,Q96RL7,P02545,Q9NR77,O15269 9 +Aplasia hypoplasia of the nasal bone 0.7659994361432243 0.9357122120937112 0.349421381248935 1.0 0.8903091444927603 2 Q6NUK1 1 +Congenital craniofacial dysostosis 0.7659994361432243 0.9357122120937112 0.349421381248935 1.0 0.8903091444927603 2 Q6NUK1 1 +Bacterial endocarditis 0.765999436143199 0.9357122120936094 0.3494213812489875 1.0 0.8903091444927603 2 P04062 1 +Reduced visual acuity 0.3452448877903377 0.9348112961860946 0.3498855570164119 1.0 0.8903091444927603 129 P33897,Q86Y39,Q9NZJ7,Q9UHX1,P50897,P00846,Q9NZ08,O43676,Q96TA2,Q9H9S5,P16278,Q9UGJ1,P17900,P49327,Q15058,Q15043,P21912,P06865,Q9NPL8,Q07021,Q86YV9,P07602,Q15051,Q96CU9,P03886,O43681,O60313,O43505,Q9Y6M9,Q9H061,O96000,O60220,Q10713,Q969G3,O00429,P01889,P51797,Q9H6K4,Q96S66,Q96AA3 40 +Abnormality of circulating leptin level 0.6267521045502664 0.9346864014776844 0.349949936949832 1.0 0.8903091444927603 4 O75844 1 +Finger agnosia 0.7657175077530163 0.9345793766150986 0.3500051114281324 1.0 0.8903091444927603 2 P05067 1 +Weakness of muscles of respiration 0.3323765826320742 0.9342118218516168 0.350194638789741 1.0 0.8903091444927603 37 Q8WXH0,Q8TD16,P50402,P10253,P50570,O95140,Q969X5,Q7LG56,Q13510,Q9BTV4,P02545,Q15067,O95831,Q7RTS9,Q9Y5L0,P22626,P12235 17 +Retinal hemorrhage 0.5053965562673027 0.9335655189008094 0.350528058797154 1.0 0.8906703677405851 7 P22413,P36543,Q9Y487 3 +Splenomegaly 0.3637966058224569 0.9307000113249873 0.3520087638411255 1.0 0.892350086854949 93 Q9NZJ7,Q9NZ08,Q15392,Q86WC4,P16278,Q96A33,P04062,P54802,Q13510,O15118,P07602,P21964,P10253,O00754,Q96RL7,Q9BT22,P08236,Q16625,Q96HY6,Q15904,Q14108,Q14739,P15586 23 +Abnormal exteroceptive sensation 0.3524913662103436 0.9304317098892396 0.3521476067782043 1.0 0.892350086854949 60 P07196,P33897,Q13045,Q9NZJ7,Q7LG56,P54802,Q8NCH0,Q9NR77,Q9NZ08,P05067,P06280,O15269,Q9H6K4,P07602 14 +Elbow flexion contracture 0.3472829790418819 0.9294496000909084 0.352656133082859 1.0 0.8926668295273021 28 Q8WXH0,P23786,P16435,P50402,Q969X5,P02545,Q7LGA3,Q96AY3,P37268 9 +Abnormality of the vasculature of the eye 0.3616951257103478 0.9264139919206182 0.354230875438259 1.0 0.8942216513910498 78 Q9NZJ7,P28070,P04439,P00846,Q9NZ08,P06280,P16278,P38435,Q9Y4P3,P17900,P49327,Q13510,P21912,P22413,P06865,P07602,P21964,P03886,Q9NW15,P10619,P01889,Q14739,Q96S66 23 +Limited elbow movement 0.3318088533712127 0.9251520878800616 0.3548868017952808 1.0 0.8945915769906021 40 Q8WXH0,P23786,P16435,Q8WVM7,P50402,Q9BTV4,Q969X5,P02545,Q7LGA3,Q96AY3,Q9H6K4,Q7RTS9,P37268 13 +Abnormal sacrum morphology 0.3291852198850579 0.9246535858208093 0.3551461298128104 1.0 0.8945915769906021 38 Q9Y4P3,P61978,Q8TAA9,Q03164,Q5H8A4,P35250,Q15125,P01889,Q8N6M0,P22413,Q14739,P04066,Q9UM00,P53701,O96028,O95202,P62258 17 +Abnormal renal cortex morphology 0.3511302082716863 0.9238341574311304 0.3555726681656919 1.0 0.8947012037987879 59 Q03252,O43707,O95470,P03886,P00403,Q8N1F7,P02545,Q96D53,P01889,P21912,P00846,Q9NZ08,Q16134,Q14108,P06280,Q86WC4,Q8NFH4 17 +Pili torti 0.7628982238511448 0.923263891756026 0.3558697000815594 1.0 0.8949613473147807 2 P02545 1 +Abnormal head movements 0.4352527067799812 0.9201648472711728 0.3574866210936198 1.0 0.8968029120560173 12 P35637,Q99720,Q96RL7,P20700,Q06787 5 +Blindness 0.3627969791217251 0.9200143837943991 0.3575652427016043 1.0 0.8968029120560173 86 Q96CU9,P33897,P17900,Q86Y39,P03886,Q9NZJ7,P50897,O43505,P00846,Q9NZ08,P06865,O43676,Q9NPL8,Q9H9S5,Q9H6K4,P07602,O96000,P16278 18 +Renal tubular dysfunction 0.3336956611276047 0.9187458789980274 0.3582285065577899 1.0 0.8973031077035227 42 Q9H267,Q96CU9,O43819,Q86Y39,Q8N183,P98164,P03886,Q7LG56,P00403,P50416,Q9Y6M9,Q16134,O43676,Q9NPL8,P40855,Q9NWS8,O96000 17 +Variable expressivity 0.3624098163420182 0.9185271347944568 0.3583429596607623 1.0 0.8973031077035227 84 Q8TD16,Q9NZJ7,P00374,Q9H9S5,P07196,P17900,O95470,Q53H12,Q13510,P00403,Q9NR77,P07602,P03886,Q15125,Q9NWS8,Q9H061,Q13586,O00429,Q70HW3 19 +Retinal degeneration 0.3534847483468711 0.9173360872759352 0.3589665526429082 1.0 0.898125710987231 63 Q9H2C2,O14773,P51648,Q10713,O00754,P04062,Q9NW15,Q13510,O60313,P50897,P04439,Q7LGA3,O75503,Q9H9S5 14 +Limited knee extension 0.7623134222669756 0.9151379238705984 0.3601192280551337 1.0 0.8986234108029626 3 Q7RTS9 1 +Eeg with focal spikes 0.541855734532979 0.9130736148536724 0.3612038261439219 1.0 0.8986234108029626 6 O75503 1 +Cold induced muscle cramps 0.7613682033192217 0.9115502655579776 0.3620055135522888 1.0 0.8986234108029626 3 P23786 1 +Frontotemporal dementia 0.4509485760609775 0.9106366265239906 0.3624868654367628 1.0 0.8986234108029626 11 O96008,P35637,Q9UQN3,Q14203,P05067,P22626 6 +Generalized muscle weakness 0.3380221759003171 0.9099838126917732 0.3628310466456967 1.0 0.8986234108029626 33 P35637,P10253,Q92804,P21912,Q9H9S5,P12235 6 +Facial hypotonia 0.4334440424062181 0.9087386610772572 0.3634880914995197 1.0 0.8987567876815389 12 P10253,P30153 2 +Amyotrophic lateral sclerosis 0.3971795002344185 0.9086076690320536 0.3635572569719307 1.0 0.8987567876815389 16 P35637,Q92804,Q99720,Q9UQN3,Q14203,P22626,Q15165 7 +Preaxial polydactyly 0.3882434285799678 0.9081949723925672 0.3637752198927533 1.0 0.8987594557188691 18 O95202,Q5H8A4,Q9UHX1,Q96J42 4 +Bowing of the legs 0.3486459641940194 0.9050479523003992 0.3654399838375788 1.0 0.900112255841245 58 Q9Y619,Q9Y4P3,P08236,O75312,Q9NX62,P16435,Q96HY6,O00754,Q32P28,Q13126,Q15643,Q9NR77,P22413,Q9UP83,Q7LGA3,Q7RTS9,P16278 17 +Delayed closure of the anterior fontanelle 0.4065561685173157 0.9039803187973958 0.3660058375163215 1.0 0.900112255841245 14 P51812,O75381,P40855,Q9Y487 4 +Abnormality of carpal bone ossification 0.4995523918771234 0.9029617915166605 0.3665461737961597 1.0 0.900112255841245 7 Q15125,Q15643 2 +Increased intracranial pressure 0.3788407514993142 0.8988761835301812 0.3687186150923072 1.0 0.9005168694935415 20 Q9NZJ7,Q969G3,P01889,P21912,Q9NZ08,P07602 6 +Multifocal cerebral white matter abnormalities 0.5386359483164012 0.8975914027930055 0.3694034241220536 1.0 0.901243678872201 6 P10253 1 +Pulmonary fibrosis 0.3667757851311801 0.895208847770096 0.3706754559155261 1.0 0.9024551502545888 22 P09601,Q8IZA0,P04062 3 +Emphysema 0.430828192241989 0.8922326419285745 0.3722682495382479 1.0 0.904440867223666 12 Q99758,Q03518,P06280 3 +Decreased circulating iga level 0.4478109741942182 0.8917759170489612 0.3725130525917219 1.0 0.9045635158134928 11 Q15904 1 +Dysarthria 0.2736796314766405 0.8855300899494081 0.3758707982102023 1.0 0.90857267857046 174 Q96D71,P33897,P35637,O14653,Q9NZJ7,Q7LG56,O75027,P00846,O76024,Q5XKP0,P07196,Q9Y4P3,P51648,P04062,O43292,Q06787,O15118,O75503,O14773,P07602,Q8IV08,Q96CU9,Q6DKK2,O00754,Q9NW15,Q96RL7,Q9NP80,O60220,P12235,Q10713,Q9P0J0,Q14108,Q7KZN9,Q9H6K4,P15586 35 +Decreased adipose tissue 0.3939667790168893 0.8854374790090818 0.3759207258703987 1.0 0.90857267857046 16 Q6NUK1,Q03252,O75844,P36543 4 +Decreased ldl cholesterol concentration 0.614967281668174 0.8847596100668211 0.3762862977406125 1.0 0.9088312658063508 4 Q15800 1 +Chronic otitis media 0.3413844908761125 0.8845151435918804 0.3764181912942308 1.0 0.9088312658063508 29 P21964,Q13045,Q5H8A4,Q03518,Q06787,O96028,O95202 7 +Median cleft palate 0.7530307301945107 0.8838536478299439 0.3767752217888933 1.0 0.9092216990291854 2 Q14739 1 +Overtubulated long bones 0.7534395496359614 0.8815432454867611 0.3780238581044897 1.0 0.9105897621319344 3 O75844 1 +Delayed fine motor development 0.4623482343955175 0.8811787301156174 0.3782210897240199 1.0 0.9105897621319344 10 Q5KU26,P16435,Q01082,P51798 4 +Tongue fasciculations 0.4164342207736824 0.8810517274021884 0.3782898231118539 1.0 0.9105897621319344 13 P51114,Q9BQT8,Q13510 3 +Capillary malformation 0.4032068341610314 0.8809955754002761 0.3783202148148574 1.0 0.9105897621319344 14 P42345,Q9UHX1 2 +Atrophy degeneration affecting the central nervous system 0.2804558580613278 0.8798463315388236 0.3789425616814581 1.0 0.9107031998192736 334 Q96D71,P33897,O75880,Q8TD16,Q86Y39,P35637,Q5KU26,Q9NZJ7,Q9UHX1,O75787,P50897,P00846,O14678,O76024,P05067,Q96TA2,O00400,P00374,Q9H490,Q86WC4,P16278,Q9H9S5,Q9H2C2,P07196,Q9UGJ1,Q01105,P17900,Q9UPT5,Q96A33,P04062,Q92804,Q13510,P00403,Q15043,Q06787,O15118,O14773,O75503,P07602,Q15165,P51812,O75208,O75845,Q6DKK2,O00754,P03886,Q96RL7,O60313,Q9BT22,P13073,Q9BUB7,Q9UP83,Q9NWS8,O60220,Q9Y619,Q96N66,P08236,Q16625,Q10713,Q99720,O00429,Q5H8A4,Q9Y320,Q7LGA3,P40855,Q13217,Q96AA3 67 +Hip pain 0.5720185414688608 0.879730179676557 0.3790054961153295 1.0 0.9107031998192736 5 O75844,P02545 2 +Abnormality of the nasolabial region 0.5719590470702135 0.8794637059131659 0.3791499035982282 1.0 0.9107031998192736 5 Q8NCH0,Q9Y487 2 +Prominent nasolabial fold 0.5719590470702135 0.8794637059131659 0.3791499035982282 1.0 0.9107031998192736 5 Q8NCH0,Q9Y487 2 +Increased skull ossification 0.7519719054326117 0.876006500433526 0.3810264999320398 1.0 0.9127625724848202 3 P54802 1 +Multiple rib fractures 0.7502114462926406 0.8726523835602293 0.3828525789574333 1.0 0.9145741137267376 2 Q15643 1 +Vacuolated lymphocytes 0.7507050197405465 0.8712317728189599 0.3836276148110027 1.0 0.9145741137267376 3 O00754,P16278 2 +Abnormal vertebral morphology 0.349092764943387 0.8710835452294869 0.3837085379394884 1.0 0.9145741137267376 119 Q13045,Q32P28,Q9UHX1,Q9H9S5,P16278,Q9Y4P3,P07237,P04062,P54802,P22413,O95202,P51812,O75845,O00754,Q8NCH0,Q15643,Q15125,Q7RTS9,P10619,Q8WTW3,Q9Y619,Q6NUK1,P16435,P08236,Q10713,Q96HY6,Q5JRA6,Q8TAA9,Q5H8A4,Q14108,Q14739,Q96AY3,O96028,P15586 34 +Hypoplasia of the odontoid process 0.5330209546267692 0.8706522392413317 0.3839440638639753 1.0 0.9146671531662256 6 Q7RTS9,P16278 2 +Tachycardia 0.339624609659222 0.8676127584395774 0.3856063595907104 1.0 0.916355091306524 29 P23786,P02545,Q99758,P21912,Q9HD47,P09493,P42892 7 +Gastroparesis 0.4437747279695934 0.8675623472232894 0.3856339665602979 1.0 0.916355091306524 11 Q04656,Q7LG56,Q96RR1,Q9BUB7,P12235 5 +Neurofibromas 0.5322561428080697 0.8669892441106433 0.3859479030313273 1.0 0.916355091306524 6 P21912,Q969G3,Q07954 3 +Abnormal pharynx morphology 0.3251156564232853 0.8665161534054011 0.3862071719089068 1.0 0.916355091306524 39 P08236,Q969G3,P54802,Q13510,P01889,Q03518,Q86YV9,Q7RTS9,P15586,P16278 10 +Ectopic anus 0.3913153008519733 0.8663492233610336 0.3862986802999959 1.0 0.916355091306524 16 Q6NUK1,P16435,Q15022,O60826,P49748,P53701,Q12768,Q9NX14 8 +Hyperreflexia 0.2658046334637773 0.8640969978890221 0.3875346080525432 1.0 0.916355091306524 264 O14949,O75787,O75027,P00846,Q9Y4P3,P17900,O15020,O14773,P07602,Q53FT3,Q96CU9,P49902,P03886,P13073,Q8N0X7,Q86XL3,Q9BSJ2,Q15067,P20700,P01889,Q9P0J0,Q7KZN9,Q9H6K4,Q12768,P33897,Q96IX5,Q9NZ08,O00400,Q5XKP0,Q9HD42,P04062,P49327,Q15058,Q9UBB4,Q9NR77,O75503,O75746,Q6DKK2,O43681,O75569,O60313,Q14203,O60220,Q9Y619,P20674,Q99720,Q14739,P40855,Q6PJG6,P35637,Q5KU26,Q9NZJ7,Q9BXW9,Q01082,Q86WC4,P55011,Q13813,Q9BRK0,O43292,O94905,Q05086,O75208,Q8N183,Q9Y276,Q9GZY8,Q9NW15,Q8NI60,Q5JRX3,Q9BQT8,Q7RTS9,Q96N66,Q6PI48,Q16625,Q15233,P35250,Q5HYK3,P07686,O43395,Q96AA3,O75381,Q8TD16,Q9H9S5,Q15043,P21912,O00754,Q9UP83,Q10713,O00429,Q9Y320 89 +Ovotestis 0.747956019171133 0.8637112646002774 0.3877465239828002 1.0 0.916355091306524 2 P53701 1 +Patellar dislocation 0.3630274484418604 0.8636931107429221 0.3877564991724733 1.0 0.916355091306524 22 Q96PU5,P21964,Q9NX62,Q6ZXV5 4 +Hypopigmented skin patches 0.3379403885786834 0.8636098304736057 0.3878022620566814 1.0 0.916355091306524 30 P21964,Q9NZJ7,P49327,Q15125,Q9NP58,P21912,Q8IZA0,P53701,P42345,P07602 10 +Micromelia 0.3430277319396476 0.8630100866475195 0.3881319211957692 1.0 0.916482268054913 25 Q15392,Q9UHX1,Q96HY6 3 +Diaphragmatic weakness 0.5313801282016644 0.8627956234322411 0.3882498458870651 1.0 0.916482268054913 6 P10253 1 +Scaphocephaly 0.5312299571137638 0.8620769444534652 0.3886451776209276 1.0 0.9169504824254529 6 P40855 1 +Abnormal cerebral ventricle morphology 0.2629026791356179 0.8605482507060348 0.3894868979570696 1.0 0.917375656691968 252 P23786,P36543,Q8TD16,Q13045,Q5KU26,Q9NZJ7,Q9UHX1,O75787,P00846,Q15392,Q86WC4,P16278,Q9H9S5,P07237,Q01105,P04062,Q9NPL8,Q6ZXV5,P07602,O95202,Q9UID3,P51812,Q96CU9,P30153,O75312,P21964,O00754,Q9HC21,Q8NCH0,Q96RL7,Q15125,O43505,Q9UP83,Q96J42,Q9Y487,P42345,Q6NUK1,P08236,P16435,Q16625,Q10713,Q03252,Q8TAA9,O00584,Q969G3,Q5H8A4,Q9Y320,P40855,O96028 49 +Hypoglycemic coma 0.4595340477359856 0.8603443824743008 0.389599234428549 1.0 0.917375656691968 9 Q16134,Q13423 2 +Abnormal size of the clitoris 0.3848279191287236 0.8592008908118811 0.3902296920014478 1.0 0.917494198543113 17 Q9Y619,P16435,P40855 3 +Pseudoarthrosis 0.7464628745543869 0.8552758941542596 0.3923984293822795 1.0 0.9196611619156932 3 O75844 1 +Pulmonary hypoplasia 0.3381893897050609 0.8538431415474564 0.393191907063354 1.0 0.9196611619156932 29 O75844,Q8TAA9,Q15643,Q14739,P98175,Q16134,O96000 7 +Acanthocytosis 0.5661920806100479 0.85367844047163 0.3932831829893046 1.0 0.9196611619156932 5 Q96RL7 1 +Abnormal sensory nerve conduction velocity 0.4583376976791234 0.8535839955945178 0.3933355293215337 1.0 0.9196611619156932 9 Q9NR77,O15269 2 +Congenital hepatic fibrosis 0.4648064426687382 0.8531347587621737 0.3935845778439661 1.0 0.9196611619156932 8 Q10713,Q96J42 2 +Hemiplegia hemiparesis 0.334443676946935 0.8523102905451779 0.3940418960219922 1.0 0.9196611619156932 48 P33897,P03886,P49327,Q7LG56,P00403,O60313,Q969G3,O00429,P50416,P01889,Q9NZ08,P22413,Q9NP80,P42345,Q9H9S5 15 +Abnormal tongue physiology 0.3729953516304065 0.8522800895122535 0.3940586541136968 1.0 0.9196611619156932 20 P10253,P51114,Q9BQT8,Q13510 4 +Hyperthyroidism 0.4243577989804135 0.8515156265049593 0.394482986592696 1.0 0.9196611619156932 12 P12235,Q7LG56,P21964 3 +Gastroesophageal reflux 0.3311247014111935 0.8511150786428485 0.3947054300613843 1.0 0.9196611619156932 137 Q13045,Q03164,Q9NZJ7,Q7LG56,Q9UHX1,Q8IZA0,O14678,P00846,Q9H2C2,Q01105,Q96A33,Q9Y584,Q06787,Q6ZXV5,O95202,P07602,P21964,P51571,P55795,Q96PU5,P12235,Q6NUK1,Q9Y619,P16435,Q99758,Q14739,O15269,O96028 28 +Neoplasm of fatty tissue 0.4242860511683748 0.8510651008696809 0.3947331904420097 1.0 0.9196611619156932 12 Q8TAA9,O95140,P21912,P22413,P29992 5 +Polycystic liver disease 0.6063734303100279 0.8485727112206626 0.3961190969411783 1.0 0.9215064449081384 4 Q9UBS4,P14314 2 +Soft skin 0.4558375412505081 0.8439382048529738 0.3987039377812769 1.0 0.9238261972980806 10 O00754,Q13126,Q9NWM8 3 +Fractures of the long bones 0.604569972231608 0.8410053113694141 0.4003449589050216 1.0 0.9253056872381388 4 Q13126 1 +Generalized osteosclerosis 0.7422187457185201 0.839364088068211 0.4012650296903495 1.0 0.9253056872381388 3 Q15392 1 +Postural instability 0.3657920671884981 0.8381862757570526 0.4019260937513604 1.0 0.9253056872381388 21 Q9NR77,O75503,P04062 3 +Submucous cleft of soft and hard palate 0.340300959744912 0.8380209904972591 0.4020189147252024 1.0 0.9253056872381388 25 O75844,O43505,Q15392,Q7LGA3 4 +Abnormal urine magnesium concentration 0.7411897378066017 0.8369986957986633 0.4025933011304197 1.0 0.9253056872381388 2 P05023 1 +Red green dyschromatopsia 0.741477733982989 0.8365914074187034 0.4028222771204193 1.0 0.9253056872381388 3 Q9H6K4 1 +Retinal pigment epithelial mottling 0.7414118205797423 0.8363448562056377 0.4029609251986858 1.0 0.9253056872381388 3 P00846 1 +Motor neuron atrophy 0.3532790421963464 0.8336452143073352 0.4044809388788315 1.0 0.9253056872381388 23 Q92804,Q99720,Q13510,P35637 4 +Gastrointestinal hemorrhage 0.3229341674071955 0.8336146011926485 0.4044981950139186 1.0 0.9253056872381388 37 Q04656,P21964,P49327,Q9UHX1,P01889,P21912,Q9NZ08,P22413,Q14739,O76024,P49257 11 +Hepatic cysts 0.5612953617714201 0.8318584550812532 0.405488844250776 1.0 0.9253056872381388 5 Q9UGP8,Q9UBS4 2 +Pseudoepiphyses 0.5611469090899082 0.8311980761321485 0.4058617414771088 1.0 0.9253056872381388 5 P51812,O95202 2 +Bone marrow foam cells 0.739212294688087 0.8281250617968718 0.4075996776700825 1.0 0.9253056872381388 3 O15118 1 +Communicating hydrocephalus 0.5602351739224246 0.8271438117844054 0.4081555543861861 1.0 0.9253056872381388 5 P07237 1 +Elevated diastolic blood pressure 0.7386523822948751 0.8270261372206998 0.4082222471693955 1.0 0.9253056872381388 2 P42892 1 +Elevated mean arterial pressure 0.7386523822948751 0.8270261372206998 0.4082222471693955 1.0 0.9253056872381388 2 P42892 1 +Elevated systolic blood pressure 0.7386523822948751 0.8270261372206998 0.4082222471693955 1.0 0.9253056872381388 2 P42892 1 +Abnormal thyroid stimulating hormone level 0.7380885255145195 0.8248134374188353 0.4094775165992923 1.0 0.9253056872381388 2 P10644 1 +Weak voice 0.5232295265875838 0.8238851818835412 0.4100048008613846 1.0 0.9253056872381388 6 O75787,P04062 2 +Abnormal metacarpal morphology 0.3259247925356104 0.8232480761804665 0.410366934469305 1.0 0.9253056872381388 35 P51812,P16435,Q9NX62,Q15643,Q32P28,Q14739,Q7RTS9,P16278 8 +Supraventricular tachycardia 0.5591690185583186 0.8224062135818014 0.4108457441533248 1.0 0.9253056872381388 5 Q9HD47 1 +Muscle fiber inclusion bodies 0.4196864017279219 0.8222317760695064 0.4109449970360366 1.0 0.9253056872381388 12 Q13586,O43676 2 +Fibrous tissue neoplasm 0.3692118898733272 0.8222244936882738 0.410949140934471 1.0 0.9253056872381388 20 Q969G3,P49327,Q13126,Q07954,Q01082,P21912,Q15392 7 +Gray matter heterotopia 0.3292471716940499 0.8215136587023464 0.4113537472633342 1.0 0.9253056872381388 33 Q6NUK1,Q9UEY8,Q86XL3,Q96PU5,Q9BSJ2,Q15058,O43505,Q06787,Q6ZXV5,Q9H9S5 10 +Aplasia hypoplasia of the femur 0.3899508682581626 0.8211798421870047 0.4115438367398565 1.0 0.9253056872381388 15 Q9UHX1 1 +Prenatal maternal abnormality 0.4072629100682835 0.8210394359159818 0.4116238056777876 1.0 0.9253056872381388 13 P16435,Q8TAA9,P02545,P50416,Q14739 5 +Urinary urgency 0.4517049025254757 0.820383415383876 0.4119975668837643 1.0 0.9253056872381388 10 Q12768,P33897,P04062,P20700 4 +Pituitary growth hormone cell adenoma 0.5996363898900556 0.8203546090662126 0.4120139836101333 1.0 0.9253056872381388 4 Q9UBS4,P10644 2 +Platyspondyly 0.3194423008674346 0.8194220029595749 0.4125456855934426 1.0 0.9253056872381388 38 Q6NUK1,Q96HY6,O00754,Q15643,Q32P28,Q14739,Q96AY3,Q7RTS9,P16278 9 +Urticaria 0.3939762585138125 0.8179173545947577 0.4134043799967442 1.0 0.9260815153440058 14 P21912,P51648 2 +Shoulder dislocation 0.5983738135749765 0.8150822333904381 0.4150252406377188 1.0 0.9286454497592233 4 Q6ZXV5 1 +Megaloblastic anemia 0.4576063966383726 0.813481275676103 0.415942177414442 1.0 0.9294395440402512 8 P00374 1 +Hypoketotic hypoglycemia 0.4574680612240842 0.812721410391717 0.4163778029027116 1.0 0.9294395440402512 8 P23786,Q16836 2 +First degree atrioventricular block 0.7350166285014237 0.8124874619488098 0.4165119781046855 1.0 0.9294395440402512 3 Q9HD47 1 +Abnormal foot bone ossification 0.5971947002747005 0.8101631323379138 0.4178464236178061 1.0 0.9294395440402512 4 Q15125,Q14739 2 +Abnormal brain lactate level by mrs 0.4495291859565516 0.808011359211016 0.4190840430324967 1.0 0.9294395440402512 10 P21912,P03886,P00403 3 +Intellectual disability progressive 0.3831476578229914 0.8077780655178594 0.4192183542813148 1.0 0.9294395440402512 16 Q9H9P8,Q05086,Q6P1N0,Q15067,O95721,P53701,Q9NX14 7 +Opisthotonus 0.3367979207633074 0.8059998356770806 0.420242943848458 1.0 0.930331267938564 25 P35637,P04062,Q99720,O60313,P07602 5 +Abnormal ossification involving the femoral head and neck 0.5553706900051332 0.8055580160148352 0.4204977417277633 1.0 0.930331267938564 5 Q14739 1 +Hypoproteinemia 0.7323745064861806 0.8026692127649635 0.4221659522160927 1.0 0.931470984219158 3 Q9H3H5,Q9UJS0 2 +Purpura 0.3496450157216388 0.8023865173698113 0.422329409735235 1.0 0.931470984219158 23 P21964,Q13586,P04062,Q8NCH0,P38435 5 +Chronic diarrhea 0.361274739255532 0.8014202230035552 0.4228884115058817 1.0 0.9316509095977544 21 Q15904,Q96A33,Q13510 3 +Abnormal femoral neck head morphology 0.333799364140933 0.800523026435134 0.4234078278891462 1.0 0.9322434222636096 52 P02545,P55011,P16278,Q96A33,P22413,P51812,O00754,Q15643,Q9Y487,Q7RTS9,Q9H173,Q96AY3,O75844,Q9Y619,Q8WTW3,Q04656,Q96HY6,Q14739,Q7LGA3,O75718,P04066 21 +Abnormality of hindbrain morphology 0.2722758317378677 0.8001361878914527 0.4236318965017569 1.0 0.9322434222636096 308 Q96D71,P36543,O75787,P00846,P46977,Q96TA2,P00374,Q9H490,Q9Y4P3,O15020,O14773,Q96CU9,P15291,P13073,Q8N0X7,Q8WTW3,P20700,Q14108,Q9H6K4,Q12768,Q8NFH4,P23786,O00400,Q5XKP0,P51572,Q9HD42,Q92643,Q15058,Q9UBB4,O75503,Q15051,Q8IV08,P51812,Q9C0B1,Q6DKK2,O60313,Q96RR1,O43505,Q96J42,P51970,P12235,Q99720,P35637,Q9NVI7,Q9UPT5,O43292,O95202,Q9UID3,P30153,O75312,O75208,P55795,Q9NW15,Q15125,Q9BT22,P98175,P16435,Q16625,Q8TAA9,Q5H8A4,Q5HYK3,O96028,Q8TD16,Q7LG56,Q9H9S5,Q9UGJ1,Q15043,P21912,Q06787,O75845,O00754,Q9HC21,Q9UP83,Q9Y487,Q6NUK1,Q10713,Q969G3,O00429,Q9Y320,Q13217 80 +Male pseudohermaphroditism 0.518111365592077 0.7995604956306659 0.4239654833366404 1.0 0.9322434222636096 6 P53701,Q96J42 2 +Abnormal peripheral nervous system morphology 0.267306733408358 0.7975776307150432 0.4251156364087207 1.0 0.9336477497899224 175 P33897,O75381,P35637,Q9NZJ7,Q7LG56,Q9UHX1,P00846,O76024,O95721,Q9NVI7,Q9BPX6,Q9H9S5,P07196,Q13510,P00403,Q15043,Q9NR77,P21912,P07602,Q8IV08,P51812,Q6DKK2,P03886,Q96RL7,O60313,Q9BQT8,P12235,Q9Y619,Q99720,P40855,O15269 31 +Type ii lissencephaly 0.7308431819661093 0.7969893659020394 0.4254572073400084 1.0 0.9336477497899224 3 O43505 1 +Small placenta 0.7307131695768408 0.7965075006364194 0.425737117628596 1.0 0.9336477497899224 3 O75844 1 +Short umbilical cord 0.7307131695768408 0.7965075006364194 0.425737117628596 1.0 0.9336477497899224 3 O75844 1 +Polydactyly 0.3352848994057444 0.7959036438854465 0.4260880431417422 1.0 0.9338229005766524 54 Q13045,Q9BXW9,Q9UHX1,Q9UM00,O95202,P61978,P30153,O75845,P21964,Q15125,P98175,Q96J42,Q9Y366,Q10713,Q5H8A4,Q15067,Q14739,O96028,Q12768 19 +Type i diabetes mellitus 0.4317053352335134 0.7955512541585859 0.4262929089765648 1.0 0.933832231193369 11 P03886,P00403,Q13217 3 +Abnormality of pain sensation 0.3294608035819846 0.794057859109346 0.4271617488430903 1.0 0.934245126119475 31 P07196,P33897,Q13045,Q8NCH0,Q9NR77,O15269 6 +Equinovarus deformity 0.5169346592944519 0.793981059107614 0.4272064580682282 1.0 0.934245126119475 6 Q9NR77,Q96RL7 2 +Aplasia hypoplasia of the nipples 0.36562866645492 0.793847556376272 0.4272841833530316 1.0 0.934245126119475 20 Q6NUK1,Q96A33,Q5H8A4,O96028,O95202,Q12768 6 +Abnormal meningeal morphology 0.3344825738526423 0.7913434078661654 0.4287436243909894 1.0 0.936556345161922 26 P21964,Q8TAA9,O75845,Q9UHX1,Q15904,Q9H9S5 6 +Pectus carinatum 0.3192298597971297 0.7891683249636464 0.4300136323736996 1.0 0.93844981654926 40 P51812,Q9Y619,O00754,P55795,Q15643,Q7RTS9,Q9NVI7,P16278,Q96AY3 9 +Abnormal sputum 0.5158277161083186 0.7887370475783106 0.4302657099650742 1.0 0.9385599249706748 6 P01889,Q9NZ08 2 +Tinnitus 0.380229386461813 0.7869473461700255 0.4313126898588693 1.0 0.9390835225879496 16 P21912,Q9NR77,Q9NR28,Q15043 4 +Weakness due to upper motor neuron dysfunction 0.3011974384375597 0.7855611671548675 0.4321246222460715 1.0 0.9400673670553464 156 P33897,P35637,Q9NZJ7,Q7LG56,O75787,P00846,Q9NZ08,O00400,Q5XKP0,P51572,Q9H9S5,P17900,P04062,P49327,Q13510,P00403,Q9BRK0,P21912,P22413,P07602,Q15051,Q96CU9,P49902,Q6DKK2,O00754,P03886,O43681,Q13423,O60313,P50416,Q9UBX3,Q9NP80,Q7RTS9,P42345,Q8N0X7,Q9Y619,Q969G3,O00429,P20700,P01889,Q9P0J0,Q7KZN9,Q9H6K4,Q12768 44 +Lipoma 0.5149983481688178 0.7848110168273743 0.4325643798442788 1.0 0.940489111711872 6 Q8TAA9 1 +Flat occiput 0.3681944543131968 0.7825616549132981 0.4338845663406543 1.0 0.9411615360278404 19 O75381,Q05086,P52732,O00754,Q8N6M0,Q9BUB7,P40855,P56589 8 +Multiple prenatal fractures 0.4755993473245952 0.7785809247815318 0.4362266192882704 1.0 0.9431653101657682 7 Q14739 1 +Microdontia 0.3289935089239172 0.7770281630353676 0.4371421547054888 1.0 0.9442676242014156 30 Q6NUK1,Q9Y619,P07237,Q96A33,Q7LGA3,Q9Y487 6 +Positional foot deformity 0.3460576901503988 0.7743233087674883 0.4387396231244744 1.0 0.9451142571956264 112 P36543,Q8TD16,Q969X5,Q9UHX1,P02545,Q9NVI7,Q15392,P07196,Q8TB36,Q96A33,Q9NR77,Q6ZXV5,O95202,P49902,Q15022,P21964,O75845,Q8NCH0,O00754,Q9HC21,Q15125,P98175,Q96J42,Q9NWM8,Q9Y487,Q7RTS9,Q8WTW3,Q9Y619,P08236,P16435,Q8TAA9,Q5H8A4,Q96AY3,O96028 34 +Abnormal circulating androgen level 0.4117392162434832 0.7726693345445503 0.4397180994702125 1.0 0.9451142571956264 12 P16435,Q13423 2 +Abnormality of upper limb epiphysis morphology 0.3729364689091917 0.7718629751268862 0.4401955882683281 1.0 0.9451142571956264 17 P51812,Q9Y366,P16435,Q5JRA6,Q15643,Q7RTS9,O96028,O95202,P10644 9 +Osteolytic defects of the distal phalanges of the hand 0.5879099159249327 0.771597346500491 0.4403529463711173 1.0 0.9451142571956264 4 O75844 1 +Pancreatic islet cell hyperplasia 0.7233793171476846 0.7694213785454749 0.4416432013161533 1.0 0.9451142571956264 3 Q14739 1 +Pigmentary retinopathy 0.3317640675909896 0.7676880837365712 0.4426725173324186 1.0 0.9451142571956264 53 Q16836,Q96CU9,P03886,Q7LG56,P00403,Q9P0J0,P21912,P00846,Q7KZN9,Q9UG56,O76024,Q9H9S5,Q96S66 13 +Hemoptysis 0.546715433432553 0.767355183087641 0.4428703671034375 1.0 0.9451142571956264 5 P01889,Q9NZ08 2 +Macrogyria 0.5107875140111418 0.7649190358460047 0.4443197578625519 1.0 0.94633465880401 6 O43505,Q15392 2 +Urinary incontinence 0.3253043873120244 0.7647822899032917 0.4444011953051698 1.0 0.94633465880401 47 P51812,P07196,P33897,P35637,Q8TAA9,Q9NZJ7,O43681,Q99720,Q969G3,Q9UBB4,Q06787,Q9UP83,P07602,Q12768 14 +Decreased activity of the pyruvate dehydrogenase complex 0.350947630121773 0.7627576428590989 0.4456079463744253 1.0 0.9476277365031844 22 Q9P0J0,Q96CU9,Q9P0J1 3 +Tics 0.4715659677876711 0.7578503926955777 0.4485405506544544 1.0 0.9476277365031844 7 Q9UHX1 1 +Spondyloepimetaphyseal dysplasia 0.4472501826148411 0.7568330170884152 0.4491499093323614 1.0 0.9476277365031844 8 Q96HY6 1 +Abnormal thalamic size 0.7195504779938589 0.7553577197139275 0.4500343747049782 1.0 0.9476277365031844 3 Q9UPT5 1 +Aplasia hypoplasia of the ribs 0.3305535450534769 0.7552182063729146 0.4501180663309729 1.0 0.9476277365031844 26 Q9Y619,Q96HY6,Q8TAA9,Q03164,Q15643,Q9UHX1,Q14739 7 +Widened cerebral subarachnoid space 0.7193966609147341 0.7547938884771607 0.4503726614479511 1.0 0.9476277365031844 3 P03886 1 +Short nail 0.543715239589067 0.7541792756724393 0.4507415800846679 1.0 0.9476277365031844 5 O75844,Q9Y487 2 +Cerebral calcification 0.3133407447098889 0.7538954275702672 0.4509120164026967 1.0 0.9476277365031844 38 P23786,Q16625,O75845,O00584,P03886,O00429,P00403,O60313,P05067 9 +Congenital ichthyosiform erythroderma 0.5072726396926069 0.7483699934767553 0.4542370165946683 1.0 0.9535210228174986 6 P04062 1 +Prominent superficial blood vessels 0.4237049397358031 0.7482145646861118 0.4543307472844708 1.0 0.9535210228174986 11 Q6NUK1,O75844,P36543,Q9Y487 4 +Congenital contracture 0.3214294870832934 0.7473690633220237 0.4548408142986144 1.0 0.9541613296800588 45 O75844,Q9H267,Q9HD42,Q8TD16,Q9UPT5,Q96A33,Q969X5,P04062,Q15058,Q8NCH0,P02545,Q96AY3,Q15392,Q9H9S5,Q96AA3 15 +Congenital malformation of the right heart 0.4391714259451146 0.7460938524987586 0.4556107226455179 1.0 0.9544684494247124 9 P01889,O15460,Q12768,P40855 4 +Hypertrophic cardiomyopathy 0.3411386034252113 0.745461381190398 0.4559928490174068 1.0 0.9544684494247124 117 Q8WXH0,Q96IX5,Q86Y39,P13473,P02545,P00846,O43676,P06280,Q5XKP0,Q9NVI7,P16278,Q9Y4P3,Q53H12,P54802,P00403,P21912,Q9NPL8,Q96CU9,Q9C0B1,Q16836,P50402,P10253,Q9BTV4,P03886,Q96I36,Q13423,O60313,P50416,Q9Y6M9,Q9BUB7,Q9H061,O96000,P12235,P01889,Q9P0J0,Q7KZN9,P09493,P15586 38 +Spastic paraplegia 0.3304657914513307 0.7431543544790208 0.4573882349133211 1.0 0.9560584793540682 54 Q9Y619,P33897,Q96CU9,P49902,O00754,Q9BRK0,P04062,O00429,O60313,Q9P0J0,P00846,Q7KZN9,O00400,Q8N0X7 14 +Intestinal malrotation 0.3227579965882852 0.7418538764116251 0.4581758737494517 1.0 0.9564164539478464 32 O75312,P21964,Q8NCH0,Q14739,O95202,Q15392 6 +Hypoplastic heart 0.715736040609138 0.7414024725674999 0.4584494457516292 1.0 0.9565585701361876 3 Q12768,Q8N3U4 2 +Hypoparathyroidism 0.3826130071223214 0.7409474629515256 0.45872529569372 1.0 0.956705309791338 14 P03886,P00403 2 +Bilateral ptosis 0.3948053430914587 0.7402597034412315 0.4591424269904776 1.0 0.9568253134941954 13 Q7LG56,O60313 2 +Functional abnormality of the gastrointestinal tract 0.2687932381467057 0.7369947507341111 0.4611255415784689 1.0 0.9584524384944422 304 Q96D71,P33897,P35637,Q13045,Q03164,Q9NZJ7,Q7LG56,Q9UHX1,Q8IZA0,O14678,P00846,Q9NZ08,O76024,P05067,P06280,Q9H2C2,Q9Y4P3,Q01105,Q96A33,Q9Y584,Q9P0J1,Q13510,P04062,P00403,Q9NR77,P21912,P22413,Q06787,Q6ZXV5,O15118,Q01844,P07602,O95202,P21964,P51571,P55795,Q96PU5,P03886,O00754,Q96RL7,O60313,P49257,P42892,Q8N0X7,O60220,P12235,Q9Y619,Q6NUK1,P16435,Q99720,O00429,Q15067,P20700,P01889,Q99758,O15460,Q14108,P08183,Q14739,O15269,O96028,P15586 62 +Vocal cord paralysis 0.3583935494007912 0.736855552697072 0.4612101959672503 1.0 0.9584524384944422 20 Q8WXH0,Q8TB36,P50402,Q9BTV4,P02545,Q9NR77,P21912 7 +Enlargement of the wrists 0.7149703975190307 0.7352665239824764 0.4621771915334163 1.0 0.9595974714013586 2 P22413 1 +Hyperpituitarism 0.3579490370488725 0.7333689941378385 0.4633334048130142 1.0 0.9605695614491488 20 P16435,P33897,Q06787 3 +Motor deterioration 0.53881220768996 0.7327265853489446 0.4637252057716505 1.0 0.960676828156223 5 O75503 1 +Lagopthalmos 0.712650965368079 0.7301576070945601 0.4652938520477576 1.0 0.9629858410928592 3 O75844 1 +Retinal coloboma 0.4356946921527368 0.729885140771536 0.4654603958021339 1.0 0.9629858410928592 10 Q9UHX1 1 +Vascular neoplasm 0.3106079598731038 0.7246746903335329 0.4686516256832485 1.0 0.9661962706020228 38 P16435,Q5H8A4,Q9UHX1,P21912,Q7LGA3,O96028,O95202,P10619 8 +Posterior embryotoxon 0.3516907090039932 0.7239549258813693 0.4690934077395516 1.0 0.9661962706020228 21 Q9Y4P3,O75381,P21964,P35250,Q7LGA3,P40855,Q96DF8,P53701,Q9NX14 9 +Abnormality of circulating adrenocorticotropin level 0.4343060930782699 0.7221019239458542 0.4702318154254881 1.0 0.9661962706020228 10 P16435,Q13423 2 +Thoracolumbar kyphosis 0.5015753063730264 0.7216602608502027 0.4705033799721603 1.0 0.9661962706020228 6 O00754,P04062 2 +Respiratory failure 0.3414780782471182 0.7216052768660158 0.470537193929861 1.0 0.9661962706020228 72 P23786,Q9Y619,Q8TD16,P35637,P10253,Q92804,Q9NZJ7,Q13510,Q70HW3,Q9BT22,Q9BUB7,Q86WC4,Q5XKP0,P07602,Q9H9S5,Q15165 16 +Symptomatic seizures 0.4407273083046062 0.7214307434750291 0.47064453706812 1.0 0.9661962706020228 8 Q16836,Q13423 2 +Distal arthrogryposis 0.5356596798217312 0.7189882354313852 0.4721481684016497 1.0 0.9661962706020228 5 Q96A33 1 +Talipes equinovarus 0.3461269660800743 0.7184748481312957 0.4724645508175236 1.0 0.9661962706020228 88 P36543,Q8TD16,Q969X5,Q15392,Q8TB36,Q96A33,Q9NR77,Q6ZXV5,O95202,P49902,Q15022,P21964,O75845,Q8NCH0,O00754,Q9HC21,Q15125,P98175,Q9Y487,Q9NWM8,Q7RTS9,Q8WTW3,Q9Y619,P08236,P16435,Q8TAA9,Q5H8A4,Q96AY3,O96028 29 +Ventricular tachycardia 0.3751075054985698 0.7183086967510498 0.472566969032707 1.0 0.9661962706020228 15 P23786,Q9BTV4,Q9HD47,P09493,Q9NX14 5 +Tongue nodules 0.710459543275989 0.718087102576512 0.4727035820450269 1.0 0.9661962706020228 2 P98175 1 +Abnormal pyramidal sign 0.3244177073136148 0.7180406853709146 0.4727322010489554 1.0 0.9661962706020228 135 P33897,P35637,Q9NZJ7,Q7LG56,O75787,O75027,P00846,Q9NZ08,O00400,P51572,Q9H9S5,P07196,P51648,P17900,Q9BRK0,P49327,Q15043,Q9UBB4,Q9NR77,P21912,O14773,P07602,P51812,P49902,Q6DKK2,O00754,O43681,O60313,Q8N0X7,O60220,Q9Y619,Q99720,O00429,Q15067,P20700,P01889,Q9P0J0,Q13217,Q9H6K4,Q12768 40 +Mottled pigmentation 0.7090977773380293 0.7172546342007874 0.473216993782134 1.0 0.9661962706020228 3 O75844 1 +Extrapyramidal muscular rigidity 0.4630025629518868 0.7140948378242944 0.4751685378096457 1.0 0.9666046672544756 7 Q9H6K4,Q9BPX6 2 +Dysmenorrhea 0.7093318297152599 0.7138086062874789 0.4753455371786375 1.0 0.9666046672544756 2 P02545 1 +Pituitary prolactin cell adenoma 0.7093318297152552 0.7138086062874602 0.475345537178649 1.0 0.9666046672544756 2 P10644 1 +Elevated circulating growth hormone concentration 0.7093318297152552 0.7138086062874602 0.475345537178649 1.0 0.9666046672544756 2 P10644 1 +Fat malabsorption 0.432651281885237 0.7128421257221005 0.4759434549745931 1.0 0.9666046672544756 10 Q96A33 1 +Ecchymosis 0.3904310458626004 0.7121447248924351 0.4763751612852984 1.0 0.9666046672544756 13 Q8NCH0,P04062 2 +Abnormal vitamin b12 level 0.438818879621876 0.7111187580716459 0.4770106468940118 1.0 0.9666046672544756 8 P33897,O14678 2 +Hemorrhage of the eye 0.3902670416294659 0.7110934887947084 0.4770263045812775 1.0 0.9666046672544756 13 P50570,P22413,P36543,Q9Y487 4 +Abnormal ilium morphology 0.3262921731091724 0.7106557100879171 0.477297611532816 1.0 0.9666046672544756 25 P51812,Q8TAA9,O00754,Q15643,P01889,P22413,Q7RTS9,P16278 8 +Diminished motivation 0.3249056183885969 0.7101908606451818 0.4775857875876275 1.0 0.9666046672544756 27 P17900,P35637,P04062,Q96RL7,P06865 5 +Pleural effusion 0.3901069765047445 0.7100677087025904 0.4776621496300053 1.0 0.9666046672544756 13 P01889,Q9NZ08,Q14739,Q9UID3 4 +Nyctalopia 0.3180764258867954 0.7098288155943618 0.4778102976019456 1.0 0.9666046672544756 33 Q10713,Q6P4Q7,O75381,O75312,Q13586,P40855,Q9Y287,P38435 8 +Thickened calvaria 0.432151924134637 0.7071960469964518 0.4794446547774167 1.0 0.9666046672544756 9 P51812,Q7RTS9,P16278 3 +Meningocele 0.3894738510599083 0.7060123321622168 0.4801804683692823 1.0 0.9668071146591516 13 P21964,Q8TAA9,Q9H9S5,O75845 4 +Ocular pain 0.5707134169493607 0.7010667870105751 0.4832613363793285 1.0 0.9704838312535696 4 Q15043 1 +Tetraplegia tetraparesis 0.3215016616186663 0.700231418498238 0.4837827934799734 1.0 0.9705821059881116 49 P33897,P17900,P35637,Q9NZJ7,Q13423,P00846,Q9UBX3,Q7RTS9,P07602 9 +Abnormality of salivation 0.3181902771906666 0.7001681093668939 0.4838223250014746 1.0 0.9705821059881116 46 P51812,Q03252,Q05086,P35637,P55795,Q92804,Q8N0X7,Q96RL7,P01889,O75787,Q01082,Q9NR77,Q14203,Q14739,P15586,P55011,Q15165 17 +Muscle spasm 0.3359317302068183 0.6982601544293433 0.4850145130604792 1.0 0.9706545822427048 66 P23786,P35637,P13473,Q7LG56,P53985,Q9NP58,P00846,P06280,Q9H9S5,P05023,P07196,Q92804,P04062,Q9NR77,Q15165,Q96RR1,P12235,Q13586,Q5H8A4,Q9H6K4,Q12768 21 +Abnormality of epiphysis morphology 0.3377121862874357 0.6974733886826444 0.4855065875809123 1.0 0.9708046242221422 69 O75381,Q9HC07,P16278,P38435,O95202,Q15051,P51812,Q15643,Q15125,Q9UG56,Q7RTS9,Q9H173,Q9Y619,P08236,P16435,Q9Y366,Q96HY6,Q5JRA6,Q14739,Q7LGA3,P40855,O96028 22 +Respiratory tract infection 0.2700593883505696 0.6941913750775102 0.4875622007900628 1.0 0.9720927174759724 171 O43707,Q12768,P09601,Q9NZJ7,Q8N1F7,Q9UJW0,O95721,Q86WC4,P16278,Q9Y4P3,P04062,P54802,Q13510,Q03518,Q9NPL8,Q86YV9,P07602,O95202,Q9UID3,P10253,O00754,Q15643,Q96D53,Q8N5M9,Q9Y487,Q7RTS9,O60220,Q6NUK1,P08236,Q969G3,Q5H8A4,P20700,P01889,Q99758,O15460,O96028,P15586 37 +Cardiomegaly 0.3097061493071672 0.6939282781899299 0.4877271885819443 1.0 0.9720927174759724 37 P23786,Q9Y4P3,P20674,P10253,Q15233,P13473,P04062,P54802,P35250,P50416,P22413,Q14739,P07686,Q07021,P10644 15 +Abnormality of the tongue 0.343091964376459 0.6936141518904468 0.4879242163214508 1.0 0.9720927174759724 103 O75381,P02545,Q01082,Q9H9S5,P16278,P07196,Q9Y4P3,Q96A33,P49327,Q13510,P21912,O94905,P51114,Q9C0B1,P61978,Q05086,P10253,O00754,Q96RL7,P98175,Q96J42,Q9BQT8,Q9NWS8,O75844,Q6NUK1,Q03252,Q10713,Q969G3,P35250,P20700,P01889,O15460,P07686,Q7LGA3,P40855 35 +Poor gross motor coordination 0.5688357505841005 0.693445173590227 0.4880302214267127 1.0 0.9720927174759724 4 O75503 1 +Calvarial skull defect 0.4290303962317746 0.6926423835491118 0.4885340051248306 1.0 0.9724554289927252 10 Q14739,Q5H8A4,O95202 3 +Abnormal tongue morphology 0.341771686692413 0.6913485306369305 0.4893465405830874 1.0 0.9727035627883062 79 P02545,Q01082,Q9H9S5,P16278,P07196,Q9Y4P3,Q96A33,P21912,O94905,Q9C0B1,P61978,Q05086,P10253,O00754,Q96RL7,P98175,Q96J42,O75844,Q6NUK1,Q03252,Q10713,P35250,P20700,P01889,O15460,P07686,Q7LGA3 27 +Abnormality of the nasal bone 0.7018711258673672 0.6911780620045049 0.4894536485626135 1.0 0.9727035627883062 3 Q6NUK1 1 +Enuresis 0.7031294051311014 0.6903981540978459 0.4899438372402154 1.0 0.972990001003926 2 Q9UJS0 1 +Lower limb hypertonia 0.3982201908777927 0.6892749687711395 0.4906502469173441 1.0 0.9735621907076883 12 O00400,Q14739 2 +Esodeviation 0.3097880880427769 0.6880523434714603 0.4914198196819508 1.0 0.9738889373575716 40 Q5KU26,P04062,Q9UHX1,P51797,Q9NVI7 5 +Wormian bones 0.3519378923305241 0.6864133307197616 0.492452500525856 1.0 0.9744512200309834 20 O75844,P07237,Q32P28,P02545,Q9Y487,Q96AY3 6 +Hypoplasia of the brainstem 0.3183767216079296 0.6863591302353205 0.4924866700952792 1.0 0.9744512200309834 31 Q10713,Q9UPT5,O43505,Q6ZXV5,Q9H9S5 5 +Olivopontocerebellar hypoplasia 0.5280875122948978 0.6861794370156814 0.4925999630454407 1.0 0.9744512200309834 5 P30153 1 +Functional abnormality of male internal genitalia 0.318308291996373 0.6856988671159763 0.4929030213080225 1.0 0.9744512200309834 31 P33897,P04062,Q13423,O76024 4 +Abnormal lung development 0.3251759229165292 0.6855731726237315 0.4929823035817327 1.0 0.9744512200309834 54 O75844,P21964,Q8TAA9,Q15643,Q5H8A4,Q9UHX1,Q14739,P98175,Q16134,O96028,O95202,O96000 12 +Diffuse white matter abnormalities 0.4128849007458961 0.6848271375146447 0.4934530086288911 1.0 0.974648171840682 11 P16278,Q9H936,Q9H9S5,O43819 4 +Central nervous system cyst 0.3301949557702583 0.6831112514911525 0.4945365462156625 1.0 0.975225750393824 60 P23786,P15291,P36543,Q9BSJ2,Q969G3,Q9UHX1,Q15125,O43505,P00846,Q9Y487,Q96J42,O96028,O95202,Q9H9S5,Q9UID3 15 +Abnormality of the spleen 0.3277335532224568 0.6829615350264859 0.4946311485885755 1.0 0.975225750393824 129 Q9NZJ7,Q9NZ08,Q15392,Q86WC4,P16278,Q96A33,P04062,P54802,Q13510,O15118,P07602,O95202,P21964,P10253,O75845,O00754,Q96RL7,Q9BT22,Q9UP83,Q96J42,P10619,P08236,Q16625,Q96HY6,Q13586,Q15904,Q14108,Q14739,O96028,P15586 30 +Limited hip movement 0.3603109005597829 0.6803025910432193 0.4963128842638884 1.0 0.9755567693326216 17 O75844,Q8TD16,Q969X5,Q7LGA3,Q96AY3 5 +Serositis 0.3409336478684954 0.6800694270471628 0.4964605017233796 1.0 0.9755567693326216 22 O43707,Q96D53,Q8N1F7,P01889,O15460,Q9NZ08,Q8NFH4 7 +Periventricular cysts 0.4923892276167239 0.6789251297163937 0.4971853021802088 1.0 0.976463441947735 6 O95202 1 +Mandibular prognathia 0.3126531835500676 0.6786548703412888 0.497356567316451 1.0 0.976463441947735 43 P51812,O00754,Q13045,Q9UHX1,Q06787,Q7RTS9,Q9NVI7,P16278 8 +Female hypogonadism 0.5260702538663946 0.6774869188125697 0.4980970670032558 1.0 0.9771127784905228 5 O75844 1 +Abnormal arachnoid mater morphology 0.4262929413360173 0.677430002661479 0.4981331677234666 1.0 0.9771127784905228 10 Q9UHX1 1 +Pes valgus 0.4262406944439953 0.677140173723372 0.4983170217264234 1.0 0.9771127784905228 10 Q5H8A4,Q9UHX1 2 +Generalized onset seizure 0.3385322912219843 0.6757910482196553 0.499173319028471 1.0 0.9778954723570747 112 O14653,Q9NZJ7,P00846,P00374,Q9NVI7,Q86WC4,P16278,Q01105,P04062,Q13510,O43292,P21912,O75503,P07602,P51812,P03886,Q9NW15,P42345,Q9Y619,Q96N66,O00429,Q5HYK3,Q14108 23 +Neurodegeneration 0.3172202533035126 0.6752093965296841 0.4995427375338237 1.0 0.9778954723570747 31 P33897,P17900,P35637,Q6DKK2,Q92804,Q15165 6 +Abnormal labia morphology 0.3571481713683925 0.6751877569608766 0.4995564840526583 1.0 0.9778954723570747 18 Q6NUK1,Q9Y619,P16435 3 +Limited elbow extension 0.3724234636725825 0.6727637560439743 0.5010975992369944 1.0 0.9787489789103182 14 Q9H6K4,P16435,Q7RTS9,Q8WVM7 4 +Bulbar palsy 0.3954883462895324 0.6725901816173244 0.5012080497941116 1.0 0.9787489789103182 12 P33897 1 +Axial muscle weakness 0.5248880517509682 0.6724025373640805 0.5013274679047726 1.0 0.9787489789103182 5 Q9H9S5,Q8TD16 2 +Spontaneous abortion 0.6966023024352347 0.6723136997667979 0.5013840100266638 1.0 0.9787489789103182 3 P22413 1 +Facial diplegia 0.3841419684997411 0.6719935167973149 0.5015878236612759 1.0 0.9787489789103182 13 Q7LG56,Q96RR1,Q96TA2,Q9H9S5,P12235 5 +Anencephaly 0.3566957137322212 0.671857282843417 0.5016745571815293 1.0 0.9787489789103182 18 P21964,O43505,Q96J42 3 +Osteochondroma 0.6974908373273225 0.6693010979434736 0.5033034265671659 1.0 0.979463817169798 2 P10644 1 +Diminished ability to concentrate 0.5237313931290137 0.667435167196542 0.5044942089735076 1.0 0.9797332260207252 5 Q96RR1,Q7RTS9 2 +Inappropriate crying 0.430591275794265 0.6669250650486603 0.5048199996189868 1.0 0.9797438846524144 8 P07602 1 +Emg abnormality 0.3413184373913643 0.6651211679857264 0.5059729964993349 1.0 0.9797438846524144 86 Q8WXH0,Q9H3H5,P50570,P13473,Q969X5,Q9NZJ7,Q7LG56,P02545,P29992,Q9Y5L0,Q9H9S5,P42166,P07196,Q8TB36,O43819,Q13510,Q9NR77,O14773,P07602,P51114,P50402,Q9BTV4,O43681,Q9NW15,Q96RL7,P42167,O60313,Q96RR1,Q8NI60,P22626,P12235,Q04656,Q13586,P09493,O15269 35 +Decreased muscle mass 0.3438099586956618 0.6609422992641828 0.508649317977341 1.0 0.9832901059736388 21 Q8TAA9,Q8NCH0,Q7LG56,Q9Y487,O96028,O95202 6 +Visual impairment 0.2665865386021354 0.6581811690491439 0.510421723580029 1.0 0.9854886450705248 310 Q9UHX1,P50897,P00846,O43676,Q96TA2,Q9H490,P37268,Q9Y4P3,P17900,P22413,Q07021,Q86YV9,O14773,P07602,Q53FT3,Q96CU9,P03886,Q9H061,Q9BSJ2,P20700,P01889,O15460,Q7LGA3,Q9H6K4,P33897,Q86Y39,Q9NZ01,Q9NZ08,Q5XKP0,P16278,Q9HD42,Q01105,Q96A33,P98164,P49327,P00403,Q15058,O75503,Q15051,O43681,O60313,Q96RR1,O43505,Q9Y6M9,P53701,O60220,P12235,P78318,P40855,Q6PJG6,P51797,Q9Y287,Q6P1N0,Q5KU26,Q9NZJ7,Q9BXW9,Q01082,Q86WC4,P55011,P51798,O43292,P06865,Q9NPL8,Q9UID3,P30153,O96000,Q96N66,Q6P4Q7,Q96AA3,O75381,P13473,Q7LG56,P04439,Q9H9S5,Q9UGJ1,Q15043,P21912,Q9UP83,Q10713,Q969G3,O00429,Q96S66 82 +Diplopia 0.3379744043317673 0.6558532243247581 0.5119185670034878 1.0 0.9873886746453424 22 O15020,P04062,Q9NW15,P01889,O14773 5 +Abnormal circulating proline concentration 0.5591668975805141 0.6544764394080776 0.5128049014985709 1.0 0.9873886746453424 4 Q9P0J1,O96000 2 +Retinal arteriolar tortuosity 0.3925099333086941 0.6544722617152643 0.5128075921933575 1.0 0.9873886746453424 12 P00846 1 +Misalignment of incisors 0.4868552386375584 0.6533982365497362 0.513499575388745 1.0 0.9881523453636248 6 Q9BSJ2 1 +Aplasia hypoplasia of the hallux 0.3318971923808866 0.6515237792476225 0.5147084321148805 1.0 0.9896603682341052 23 Q7LGA3,O95202,Q5H8A4,Q9UHX1 4 +Abnormal dentin morphology 0.4499765481829808 0.6483210579129596 0.5167773168585099 1.0 0.9897443242625428 7 Q15643,Q96AY3 2 +Iris coloboma 0.3034181358372037 0.6482711523399763 0.5168095887754314 1.0 0.9897443242625428 38 Q10713,Q12768,P98164,Q5H8A4,Q9UHX1,Q01082,P78318,O43505,P53701,O96028,O95202,Q9H9S5,Q9NX14 13 +Abnormal urinary electrolyte concentration 0.3500762394528339 0.6447810351597402 0.5190690935628575 1.0 0.9897443242625428 19 Q9Y4P3,P35250,Q13423,P22413,Q9UBS4,P05023 6 +Paraplegia 0.3231396480599176 0.6434380273238243 0.5199399151250423 1.0 0.9897443242625428 56 Q9Y619,P33897,Q96CU9,P49902,O00754,Q9BRK0,P04062,O00429,O60313,Q9P0J0,P00846,Q7KZN9,O00400,Q8N0X7 14 +Abnormality of subcutaneous fat tissue 0.3636519393639554 0.6401738304723872 0.5220595942185642 1.0 0.9897443242625428 15 Q6NUK1,O75844,P36543,Q9Y487 4 +Turricephaly 0.405120298447237 0.6398748928321912 0.5222539378802389 1.0 0.9897443242625428 11 P07237,P16435,P21964 3 +Coxa vara 0.3545954986109093 0.6393685669638491 0.5225831924213933 1.0 0.9897443242625428 17 Q9Y487,Q96HY6,Q04656,O75718,Q93063,O95831,P22413,Q96AY3,Q7RTS9 9 +Hypermagnesemia 0.6890329856216553 0.6380064202101674 0.5234695008237122 1.0 0.9897443242625428 2 P29992 1 +Hypocalciuria 0.6890329856216553 0.6380064202101674 0.5234695008237122 1.0 0.9897443242625428 2 P29992 1 +Diabetes insipidus 0.3670922699776459 0.637476792079463 0.5238143222170191 1.0 0.9899941818596116 14 Q9H267,P01889,O15460,O76024,P06280 5 +Glomerular sclerosis 0.3059846549362839 0.6364198877931324 0.5245027816911931 1.0 0.9900307138085288 36 O43707,O95470,P03886,P00403,Q96D53,P21912,Q14108 7 +Widened subarachnoid space 0.3242181623441161 0.6362719822922419 0.5245991631777132 1.0 0.9900307138085288 24 P03886,P00403,Q01105 3 +Abducens palsy 0.5538802991407858 0.6333796874987314 0.5264857263609657 1.0 0.9914203301821584 4 P07602 1 +Hypointensity of cerebral white matter on mri 0.4467503084308597 0.6321979573513394 0.5272575319076602 1.0 0.9916143687366702 7 P07602 1 +Abnormality of facial musculature 0.3384693577610413 0.6317724507175867 0.5275355778977944 1.0 0.9916143687366702 86 P33897,O75381,Q7LG56,Q9UHX1,O75787,Q96TA2,Q9H9S5,P07196,P04062,Q13510,Q15043,P51812,P30153,P10253,O00754,O60313,Q9BQT8,P12235,Q969G3,O00429,P40855 21 +Bifid tongue 0.5532645890297802 0.6309328559968043 0.528084427712973 1.0 0.9916228362258528 4 Q9UBM7,P61978 2 +Abnormal sweat gland morphology 0.6847577529115206 0.6303949695024995 0.5284362012878554 1.0 0.9918832729818416 3 O75844 1 +Localized osteoporosis 0.686495630109955 0.6287041029815786 0.5295427914905868 1.0 0.992824744835318 2 P57740 1 +Protrusio acetabuli 0.6838987466062456 0.627382640371471 0.5304084442046075 1.0 0.992824744835318 3 Q96AY3 1 +Shallow orbits 0.4174172169039045 0.6266129440154548 0.5309129814235061 1.0 0.992824744835318 9 O75844,P07237,P02545 3 +Abnormality of female external genitalia 0.3049751882806799 0.626084827533743 0.5312593034468804 1.0 0.992824744835318 36 Q6NUK1,Q9UQE7,Q9NP72,Q9Y619,O75381,P16435,P02545,P50542,P40855,Q9NX14,P56589,P53701,Q15392,P10644 14 +Metamorphopsia 0.5520005605955107 0.6259164717438149 0.5313697299066757 1.0 0.992824744835318 4 P22413 1 +Congenital malformation of the left heart 0.5518322997103383 0.6252494181482654 0.5318073722554058 1.0 0.992824744835318 4 Q12768,Q8N3U4 2 +Fatigable weakness of respiratory muscles 0.3613187568024544 0.6244266124001769 0.5323474523766667 1.0 0.992824744835318 15 Q92804,Q7LG56,P35637 3 +Chondrocalcinosis 0.5131574040307152 0.6223709456977568 0.5336979805366842 1.0 0.993745639759306 5 P29992,Q04656,P02545 3 +Congenital nystagmus 0.3434757669238411 0.6210084723124062 0.5345940487539518 1.0 0.9946803156074974 20 P00846 1 +Recurrent pharyngitis 0.6803836776269929 0.6150970944938473 0.5384906007700749 1.0 0.9987425877673816 3 P01889 1 +Varicose veins 0.478359634958037 0.6145669331176506 0.5388407575094627 1.0 0.9989262151360212 6 P04062 1 +Myalgia 0.311205414122242 0.6134638148460034 0.5395697018777776 1.0 0.9994501898737554 47 P23786,P21964,Q13586,Q7LG56,P49327,O00429,P02545,O60313,P20700,P01889,O15460,Q9NZ08,Q14739,Q06787,P06280,P46020,Q9H9S5,P12235 18 +Aplasia involving bones of the lower limbs 0.6798839956699705 0.6133560699050761 0.5396409265689395 1.0 0.9994501898737554 3 P02545 1 +Recurrent hand flapping 0.5487766140684313 0.6131645928204188 0.5397675139296716 1.0 0.9994501898737554 4 P55795,Q06787 2 +Infantile muscular hypotonia 0.3313742706248823 0.6079502772283586 0.5432204523603055 1.0 1.0 72 P17900,P10253,O00754,Q9NZJ7,P03886,Q13510,Q15043,Q969G3,P00846,Q9UP83,Q9Y487,P07602,Q9H9S5,P16278 14 +Leukoencephalopathy 0.3367413278997332 0.6076115676590353 0.5434451268926388 1.0 1.0 100 P33897,Q86Y39,Q9NZJ7,Q7LG56,Q9UHX1,O43676,Q01105,P17900,Q9NPL8,O75503,O95202,P07602,Q53FT3,Q96CU9,P51571,P03886,O60313,Q9BUB7,O96000,O00584,O96028 21 +Preaxial foot polydactyly 0.5473117308055433 0.6073910940160313 0.5435913974248541 1.0 1.0 4 O95202 1 +Abnormal ureter morphology 0.311106573654657 0.6065769604682586 0.5441316940212708 1.0 1.0 30 O75844,P23786,Q7LGA3,Q96J42,O76024 5 +Goiter 0.413398081377921 0.6065389388216177 0.5441569334655549 1.0 1.0 10 P21912,Q7LG56,P12235 3 +Abnormality of the calf musculature 0.3540842794640329 0.6035309692787296 0.5461555196868058 1.0 1.0 16 Q96RL7,P02545,Q9NR77,Q12768,Q9H9S5 5 +Short upper lip 0.4755184966991708 0.601684962869887 0.5473838613082069 1.0 1.0 6 O95202 1 +Aplasia hypoplasia of the scapulae 0.5079203440731471 0.6002999314558682 0.5483063644074189 1.0 1.0 5 P16435,Q7RTS9 2 +Lactose intolerance 0.6757440602680447 0.5989845021976352 0.5491832193093982 1.0 1.0 3 P42345 1 +Abnormality of pancreas physiology 0.3062378225586943 0.5977678389918393 0.5499948528229979 1.0 1.0 44 P09601,P03886,P00403,Q9UHX1,Q15904,Q9NZ08,Q14739 7 +Oligohydramnios 0.3025097346996825 0.5974857611575302 0.5501831107152628 1.0 1.0 41 Q6NUK1,P23786,P51114,P16435,Q969X5,Q96I36,Q9UHX1,Q9UP83,Q9BUB7,Q07021,Q7LGA3,Q96J42 12 +Polymicrogyria 0.3326873850717393 0.596295250842166 0.5509780031488898 1.0 1.0 77 P23786,Q96N66,Q9Y487,Q16625,O75381,P36543,Q01105,Q8TD16,Q10713,O43505,Q9Y320,P40855,Q6ZXV5,O95721,P42345,Q15392,Q9H9S5,P37268 18 +Abnormal lactate dehydrogenase level 0.3303915032033416 0.5943491204143302 0.5522786312444203 1.0 1.0 22 P10253,P23786,O43505,Q96RL7 4 +Aplasia hypoplasia of the pubic bone 0.4737089011476511 0.5935089501418339 0.5528405949997361 1.0 1.0 6 O95202,Q5H8A4 2 +Short nose 0.3357118607052585 0.5934480285477886 0.5528813544606535 1.0 1.0 99 P36543,Q13045,Q03164,Q5KU26,Q9UHX1,Q9H490,Q9NVI7,Q15392,P38435,P04062,Q9NX62,O75312,O75845,Q8NCH0,Q15643,Q9Y487,P42892,P42345,O75844,Q6NUK1,P16435,Q969G3 22 +Calcification of cartilage 0.6766281364533342 0.5929285534044081 0.5532289680293443 1.0 1.0 2 P22413 1 +Ankylosis 0.4735283669944707 0.5926945288711398 0.5533856035899678 1.0 1.0 6 O75844,P16435,P22413 3 +Abnormal sternum morphology 0.3252263677767629 0.5922891856101246 0.553656956332828 1.0 1.0 124 Q03164,Q9UHX1,Q9H490,Q9NVI7,P16278,Q96A33,P04062,Q13510,P21912,Q06787,O95202,P51812,P30153,P50402,O00754,P55795,Q8NCH0,Q15643,P98175,Q9Y487,Q7RTS9,Q9Y619,P08236,Q14739,Q7LGA3,Q96AY3,O96028 27 +Synostosis of metacarpals metatarsals 0.6735917044033333 0.5915508360101341 0.5541514040457263 1.0 1.0 3 P16435 1 +Abnormal middle phalanx morphology of the hand 0.4381864414517714 0.5897669098758138 0.5553469300239593 1.0 1.0 7 Q03164,Q9UHX1,P02545 3 +Abnormality of circulating glucocorticoid level 0.3593933765942824 0.587070473653941 0.5571563768076984 1.0 1.0 14 P16435,P33897,Q13423 3 +Encephalocele 0.3471371540069488 0.5865396029565982 0.5575129562472689 1.0 1.0 17 Q96J42,O43505,Q9H9S5,Q6ZXV5 4 +Epiphyseal dysplasia 0.4719006469981248 0.585362066367157 0.5583042896057968 1.0 1.0 6 Q9HC07 1 +Abnormal nephron morphology 0.3263690531153821 0.5852646252745014 0.5583697968547934 1.0 1.0 67 P23786,Q9Y4P3,Q03252,O43707,O95470,P03886,P00403,Q8N1F7,P02545,Q96D53,P01889,P21912,Q9NZ08,P00846,Q14108,P06280,Q8NFH4 17 +Sinus bradycardia 0.6743727093318311 0.5848442568902407 0.5586524429944155 1.0 1.0 2 P02545 1 +Abnormal diaphysis morphology 0.3323269267434257 0.5833979296412598 0.5596254512380245 1.0 1.0 79 Q32P28,Q9HC07,P16278,Q9Y4P3,P07237,Q13126,Q9NR77,P22413,P51812,Q9NX62,O75312,O00754,Q15643,Q9UP83,Q96J42,Q9Y487,Q7RTS9,Q9Y619,P08236,P16435,Q96HY6,Q14739,Q7LGA3,Q96AY3 24 +Abnormality of the clitoris 0.3339213267714939 0.5829952325897243 0.5598965095748833 1.0 1.0 21 Q9Y619,P16435,P40855 3 +Enlarged cisterna magna 0.3417093982613143 0.5824224561290838 0.5602821592420102 1.0 1.0 19 Q10713,O00754,Q9NPL8,Q9H490,Q9UID3 5 +Increased serum pyruvate 0.3022236039569991 0.5818140099415174 0.5606919662319001 1.0 1.0 35 Q96CU9,Q86Y39,P03886,Q70HW3,P21912,Q9NPL8,O43676,O96000 8 +Anarthria 0.4702699708009499 0.5780354662710887 0.5632401747354008 1.0 1.0 6 Q99720 1 +Bone pain 0.310962239938885 0.5779910725927029 0.5632701465089807 1.0 1.0 26 Q14108,P04062,P07602 3 +Abnormality of the metacarpal bones 0.3055474824432835 0.5779767623554236 0.5632798080302557 1.0 1.0 45 P51812,Q6NUK1,P16435,Q9NX62,Q32P28,Q15643,Q14739,Q7RTS9,O96028,O95202,P16278 11 +Abnormality of the brainstem white matter 0.4700017844886888 0.5768323758423977 0.5640526963553598 1.0 1.0 6 P33897,Q10713 2 +Difficulty walking 0.3325020597011105 0.5740280148026303 0.5659488438494433 1.0 1.0 82 Q9H2C2,P33897,Q8TD16,P35637,O14653,Q9HC21,Q99720,Q9NZJ7,Q13510,Q969G3,Q9NR77,O43292,P00846,Q7RTS9,Q9BPX6,O14773,P07602,Q9H9S5 18 +Spinal cord lesion 0.4344617992204427 0.5714921115369372 0.5676661061099977 1.0 1.0 7 O00400 1 +Abnormal renal insterstitial morphology 0.3680248805157952 0.5708563889590063 0.5680969952726849 1.0 1.0 13 P23786,Q9Y4P3,Q9Y276,Q86YH6,P35250 5 +Abnormal brainstem morphology 0.3338849782829848 0.5700705576593943 0.5686298434194341 1.0 1.0 98 P33897,Q86Y39,Q5KU26,O43676,Q9H9S5,Q9UPT5,Q9NPL8,Q6ZXV5,Q06787,Q9UID3,Q96CU9,P30153,P03886,O60313,O43505,Q9UP83,O96000,Q10713,Q969G3,O00429,Q9Y320 21 +Abnormality of skeletal muscle fiber size 0.3273673079645975 0.5700668783136179 0.5686323388329018 1.0 1.0 22 Q13586,O60313,P02545,P51797,Q9BPX6 5 +Abnormal morphology of the musculature of the neck 0.3564018088574682 0.5676798023575066 0.5702524086020415 1.0 1.0 14 O75569,Q99720,P35637 3 +Contractures of the joints of the upper limbs 0.33140935822834 0.5651219727116094 0.5719908041411119 1.0 1.0 81 Q8WXH0,P23786,P35637,Q969X5,Q8IZA0,Q15392,P37268,P07196,Q9NR77,P50402,Q15022,Q9BUB7,Q9UP83,P42892,O75844,Q9Y619,P16435,Q99720,Q7LGA3,Q96AY3 20 +Convex nasal ridge 0.3213672041510167 0.5639618433505322 0.5727801003094846 1.0 1.0 23 Q6NUK1,O75844,O75312,P02545,O96028,O95202 6 +Constitutional symptom 0.2537180587406056 0.5637676027918245 0.5729123027406846 1.0 1.0 268 Q8WXH0,P23786,P33897,O43707,P35637,Q9NZJ7,Q7LG56,Q8N1F7,P28070,P02545,P00846,Q9NZ08,P06280,Q9H9S5,P07196,Q9Y4P3,Q53H12,Q92804,P04062,P49327,Q13510,Q07954,Q9UBB4,Q9BRK0,Q9NR77,Q15043,P21912,P22413,Q06787,Q07021,Q01844,P07602,Q15165,P51812,P21964,Q9BTV4,P50402,O00754,O43681,Q96D53,Q13423,O75569,O60313,P50416,Q96RR1,Q9UP83,Q9NP80,Q15800,P42892,P12235,O75844,Q03252,Q96HY6,Q8TAA9,Q13586,Q99720,Q969G3,O00429,Q70HW3,P20700,P01889,O15460,Q14108,Q14739,O15269,Q9H6K4,P46020,Q12768,Q8NFH4 69 +Megalocornea 0.3521222137212179 0.5630020802110958 0.5734334674349042 1.0 1.0 15 O96028,O95202,Q5H8A4,Q9H9S5 4 +Posteriorly rotated ears 0.3262839755929843 0.5626416750346355 0.5736789076266522 1.0 1.0 119 P23786,O75381,Q9UHX1,P11233,Q9H490,Q15392,Q9HC07,Q9H9S5,P37268,Q9Y4P3,P04062,O95202,Q15022,Q8NCH0,O43505,P98175,Q9UP83,Q96J42,P42892,Q6NUK1,Q9Y619,P16435,Q10713,Q5H8A4,Q7LGA3,P40855,O96028 27 +Headache 0.3296459138946017 0.5620390775159382 0.574089394847062 1.0 1.0 77 P23786,O43707,Q7LG56,Q8N1F7,P00846,Q9NZ08,P05067,P04062,P00403,P21912,Q9NQZ5,P03886,Q96D53,O60313,P12235,Q8TAA9,Q13586,Q969G3,O00429,P01889,O15460 21 +Abnormality of muscle size 0.2407449702941188 0.5608004918753995 0.5749335513533493 1.0 1.0 215 Q8WXH0,Q8TD16,P35637,P50570,P13473,Q969X5,Q7LG56,P02545,O00400,Q9NVI7,Q9H9S5,P16278,P07196,Q9Y4P3,Q8TB36,O43819,Q96A33,Q92804,Q13126,Q13510,Q9NR77,P21912,Q9NPL8,O94905,P10644,P51812,Q15165,Q9C0B1,P61978,Q05086,P50402,P10253,O14979,Q6DKK2,Q9BTV4,O00754,Q96RL7,Q9HC21,O60313,P50416,O43505,Q14203,Q9Y487,Q9NWM8,P51970,Q9BQT8,P22626,Q8N0X7,Q9H173,P12235,Q03252,Q6PI48,Q10713,Q04656,Q13586,Q6P4A7,Q99720,O00429,P35250,Q96BR5,P07686,Q7LGA3,O15269,P46020,Q12768 65 +Abnormality of the ribs 0.3270453949534298 0.5598314028632985 0.5755944418133403 1.0 1.0 72 Q12768,P50570,Q03164,Q32P28,Q9UHX1,P02545,Q9UM00,P16278,P07237,P54802,O95202,O00754,Q15643,Q7RTS9,Q8WTW3,Q9Y619,O75844,P16435,Q04656,Q8TAA9,Q96HY6,Q5H8A4,Q14739,O96028,P15586 25 +Atonic seizure 0.3150281795387381 0.557697644562678 0.57705086638062 1.0 1.0 24 O14653,Q13510,Q01105,O43292 4 +Abnormal circulating gonadotropin concentration 0.3546907401680302 0.556642307474642 0.5777718417203792 1.0 1.0 14 P16435,Q06787 2 +Aplasia hypoplasia involving the pelvis 0.3427952314709154 0.556132767249653 0.5781200963454611 1.0 1.0 17 O95202,Q5H8A4,Q96HY6 3 +Hypolipidemia 0.6661967860163567 0.5558444758915692 0.5783171780920697 1.0 1.0 2 Q10471 1 +Hypotriglyceridemia 0.6661967860163567 0.5558444758915692 0.5783171780920697 1.0 1.0 2 Q10471 1 +Increased circulating gonadotropin level 0.4040026873115661 0.5558051833182527 0.5783440417281525 1.0 1.0 10 P16435 1 +Secondary microcephaly 0.3307997122266626 0.5546102797190674 0.5791612562104242 1.0 1.0 82 Q8WTW3,Q96CU9,P36543,Q86Y39,O75208,Q5KU26,P55795,Q9HC21,Q5XKP0,Q9UHX1,Q15043,P50897,Q9BT22,Q9Y487,O95721,P00374,Q9HC07 17 +Nuclear cataract 0.5335520410676995 0.5538323692794511 0.5796935733256454 1.0 1.0 4 P08670 1 +Hepatosplenomegaly 0.2970043113062766 0.5532944976749499 0.5800617681749649 1.0 1.0 40 Q96HY6,O75845,O00754,P04062,Q13510,Q14739,P16278,P10619 8 +Abnormality of adrenal physiology 0.2960707177286785 0.5525349867804344 0.5805818706922867 1.0 1.0 37 P16435,P33897,O75381,O95470,Q13423,P40855 6 +Contractures involving the joints of the feet 0.3083988248229314 0.5516798934314356 0.5811676879866261 1.0 1.0 25 Q8WXH0,Q8TD16,P50402,P49902,P02545,O60313,Q8IZA0,Q9H9S5 8 +Abnormality of abdominal situs 0.4962026758741464 0.5515814708243137 0.5812351342354671 1.0 1.0 5 O95202,Q5H8A4 2 +Hypoplastic pubic rami 0.4962026758741464 0.5515814708243137 0.5812351342354671 1.0 1.0 5 O95202,Q5H8A4 2 +Rib segmentation abnormalities 0.4962026758741464 0.5515814708243137 0.5812351342354671 1.0 1.0 5 O95202,Q5H8A4 2 +Calvarial hyperostosis 0.4961708386243113 0.5514504353712639 0.5813249348343312 1.0 1.0 5 Q15043,P10644 2 +Gingival overgrowth 0.3017533004322573 0.5497184905999127 0.5825124723602957 1.0 1.0 33 Q9Y4P3,P08236,O75845,O00754,P35250,P20700,Q14739,Q9UM00,Q86WC4,P16278,P10644 11 +Abnormal shoulder morphology 0.2957699296749635 0.5494566096421665 0.5826921340262361 1.0 1.0 37 Q9Y619,Q9Y4P3,Q04656,Q96PU5,P02545,Q8N6M0,P22413,Q7LGA3,Q6ZXV5,Q7RTS9 10 +Beaking of vertebral bodies 0.374853037660699 0.5488751541517181 0.5830911300618258 1.0 1.0 12 P08236,P04066,Q9UM00,Q7RTS9,P16278 5 +Hyperkinetic movements 0.3641929006678617 0.5472502283490223 0.5842068326924905 1.0 1.0 13 Q9NZJ7,P07602,Q96RL7 3 +Abnormality of retinal pigmentation 0.3297477897665707 0.5462581737130255 0.5848884829605017 1.0 1.0 81 P51812,Q96CU9,O75381,P51648,Q6P4Q7,P03886,Q7LG56,P00403,Q9P0J0,P21912,P00846,Q7KZN9,P40855,O76024,Q9H9S5,Q9UGJ1 16 +Subsarcolemmal accumulations of abnormally shaped mitochondria 0.4943161407567293 0.5438300049459326 0.5865584590764215 1.0 1.0 5 P12235 1 +Birth length greater than 97th percentile 0.6625317169438883 0.5430058553143854 0.5871257709585269 1.0 1.0 2 Q15022 1 +Venous insufficiency 0.4280253483291809 0.5401923418918697 0.589064393427088 1.0 1.0 7 P04062 1 +Malabsorption 0.3160782870790068 0.5390654551363624 0.5898416907729365 1.0 1.0 59 Q9Y4P3,O75381,P09601,Q96A33,P49327,Q9UJW0,P01889,Q9NZ08,P22413,Q14739,O76024,P40855,P06280,P42345 14 +Tonic seizure 0.3059060089111485 0.537698472660149 0.5907852338684858 1.0 1.0 27 P07602,Q01105 2 +Nephrogenic diabetes insipidus 0.6608401466027715 0.5371151612616385 0.5911880687556825 1.0 1.0 2 Q9H267 1 +Limitation of joint mobility 0.3291801901382852 0.5364528879171857 0.59164558778023 1.0 1.0 108 Q8WXH0,P23786,Q8TD16,Q13045,Q969X5,P02545,O76024,P16278,P37268,Q9Y4P3,P51648,P54802,P22413,P50402,Q15022,O14979,O00754,Q9HC21,Q9BT22,Q7RTS9,O75844,P08236,P16435,Q8TAA9,P01889,O15460,Q7LGA3,Q96AY3,Q9H6K4,P15586 30 +Adipose tissue loss 0.4003147716856068 0.5361335082953345 0.5918662832705586 1.0 1.0 10 O75844,Q03252 2 +Multifocal seizures 0.4921215775467268 0.534846976267794 0.5927556762859565 1.0 1.0 5 Q96S52,Q10471,Q6PJG6 3 +Progressive cerebellar ataxia 0.2951395647298471 0.5339111623083468 0.5934029989135878 1.0 1.0 40 Q9Y619,Q96CU9,P35637,Q9P0J0,Q7KZN9,O76024,O14773 7 +Short palpebral fissure 0.3032925969696515 0.5337445455074732 0.5935182852744827 1.0 1.0 30 Q6NUK1,Q9Y619,O75844,P55795,Q9UHX1,P98175 6 +Widely spaced incisors 0.4912333759884087 0.531221896691398 0.595265020978319 1.0 1.0 5 Q9BSJ2 1 +Renal dysplasia 0.3434319295176735 0.5310583818204593 0.5953783230737892 1.0 1.0 16 Q969N2,Q8NCM8,Q8N201,O43819,Q9H936,O43505,O14936,Q9NWS8,Q9H9S5 9 +Fair hair 0.5273305608141106 0.5300444151845929 0.5960811365305425 1.0 1.0 4 P10644 1 +Aortic dissection 0.4908574678367104 0.5296895396158231 0.5963272016844718 1.0 1.0 5 P01889,P22413 2 +Single transverse palmar crease 0.3054016546517284 0.5288453519852329 0.5969127340104468 1.0 1.0 49 P51812,O75381,Q9UHX1,P98175,P40855,O96028,O95202,Q9UID3 8 +Atrial flutter 0.657738934310683 0.5263738665153305 0.5986284695736512 1.0 1.0 2 P02545 1 +Attenuation of retinal blood vessels 0.4251523141153258 0.5263428228019295 0.5986500347199628 1.0 1.0 7 P04439,P38435 2 +Spotty hypopigmentation 0.6541478993711289 0.525664160698083 0.5991215691692475 1.0 1.0 3 Q15125 1 +Tubulointerstitial nephritis 0.4245959866138579 0.5236701091242008 0.6005080091014394 1.0 1.0 7 P23786,Q9Y276,Q86YH6 3 +Flared iliac wing 0.4578658786214883 0.5229756311215179 0.600991211546938 1.0 1.0 6 P16278 1 +Middle age onset 0.3976989677329793 0.5222702205792512 0.6014822003060925 1.0 1.0 10 P07602 1 +Chronic constipation 0.3040545655758489 0.5212482257418228 0.6021938629550725 1.0 1.0 27 Q03252,P55795,P04062,P20700,P78318,Q8N6M0,Q7LGA3 7 +Dysphonia 0.2945929018239082 0.520939281440335 0.6024090699433153 1.0 1.0 36 Q9Y4P3,Q15233,Q6DKK2,Q02978,Q13510,Q96RL7,O75569,P35250,P20700,P21912,Q96RR1,Q14203,Q9H173 13 +Laryngeal dystonia 0.6526820595229276 0.5207952325835417 0.6025094245341407 1.0 1.0 3 Q96RL7 1 +Absence of pubertal development 0.5241052278593139 0.5178255814047205 0.6045799682289814 1.0 1.0 4 O75844 1 +Prenatal movement abnormality 0.3187481069467104 0.5172259569490659 0.6049984342638903 1.0 1.0 65 Q9H2C2,O75844,P51114,Q8TD16,Q13045,Q9HC21,P04062,Q5H8A4,Q70HW3,Q7KZN9,P40855,O96028,O95202 13 +Partial albinism 0.6549196504087998 0.5166757441616627 0.6053825310764145 1.0 1.0 2 Q9Y4I1 1 +Delayed menarche 0.4563269806912742 0.5162329033712476 0.6056917521355838 1.0 1.0 6 O75844,O00429,P02545 3 +Thick hair 0.4229350634384319 0.5157085990913758 0.6060579478515131 1.0 1.0 7 P36543,Q9Y487 2 +Hypopigmented macule 0.4873929039360465 0.5156196012123665 0.6061201174713342 1.0 1.0 5 Q9NP58 1 +Aplasia cutis congenita of scalp 0.4226296881410805 0.5142477585351396 0.6070787812113807 1.0 1.0 7 O95202,Q5H8A4 2 +Abnormal palmar dermatoglyphics 0.3184290841484915 0.5137872160970763 0.6074007667586105 1.0 1.0 65 P51812,O75381,Q96I36,Q8NCH0,Q9UHX1,O96028,P98175,P40855,Q9Y487,P42345,O95202,Q9UID3 12 +Aplasia hypoplasia of the uterus 0.3366641844317424 0.5136890113638065 0.6074694358806139 1.0 1.0 17 Q16740,P30153,O95202 3 +Abnormal atrioventricular valve physiology 0.3080744442673279 0.5130838506573996 0.6078926676196807 1.0 1.0 53 P36543,P02545,Q9NZ08,P06280,Q9Y4P3,O43819,P04062,P49327,P10644,P51812,O00754,P53701,Q6NUK1,O75844,Q15233,P35250,P01889,Q15904,P09493 19 +Dermal atrophy 0.2983986013694217 0.5065348576025598 0.6124812257492511 1.0 1.0 32 O75844,Q8NCH0,Q07954,P02545,P22413,Q9NWM8,P53701,Q15392,P10644 9 +Porokeratosis 0.6515365097265339 0.5051237024217182 0.6134719545954019 1.0 1.0 2 Q9H1A4 1 +Abnormal circulating tyrosine concentration 0.6512545813363494 0.5041653168397507 0.6141452106748633 1.0 1.0 2 Q9UJS0 1 +Periodic paralysis 0.6512545813363377 0.5041653168397112 0.614145210674891 1.0 1.0 2 Q9NP58 1 +Hypophosphatemic rickets 0.6512545813363289 0.5041653168396802 0.6141452106749128 1.0 1.0 2 P22413 1 +Cardiovascular calcification 0.3810001382136659 0.5039348905392044 0.6143071313355104 1.0 1.0 11 O75844,P04062,P22413 3 +Delayed ability to stand 0.6474433543529705 0.5035144055152732 0.6146026548016146 1.0 1.0 3 P10253 1 +Chorea 0.3280999922705669 0.5024181061820998 0.6153734453135664 1.0 1.0 91 Q01105,P17900,P35637,P03886,Q5XKP0,Q96RL7,Q99720,Q9P0J0,P00846,Q9H6K4,P07602 11 +Tapered finger 0.2932629207919813 0.501179294620386 0.6162449449194223 1.0 1.0 41 P51812,P23786,Q03252,Q06136,Q8NCH0,P42892 6 +Abnormal ovarian morphology 0.3021687045812513 0.5006109905292147 0.6166449260260607 1.0 1.0 26 Q9Y4P3,P16435,O75312,Q03252,P02545,P21912,P10644 7 +Anteriorly placed anus 0.3665051143157624 0.5002303791923371 0.6169128697446484 1.0 1.0 12 Q6NUK1,P16435,Q15022,P49748,P53701,Q9NX14 6 +Abnormality of limb epiphysis morphology 0.2951112052786572 0.4978949199846979 0.6185581080614702 1.0 1.0 34 P51812,O15228,Q9Y366,P16435,Q04656,Q5JRA6,Q15643,Q7LGA3,Q7RTS9,O96028,O95202,Q9H173,P10644 13 +Abnormal circulating acetylcarnitine concentration 0.4520643734212187 0.4976653524383528 0.6187199327240738 1.0 1.0 6 P23786 1 +Abnormal pulmonary thoracic imaging finding 0.313013290623409 0.4959032332969703 0.6199626848484976 1.0 1.0 23 P04062,Q9NZ08,Q13510 3 +Abnormal csf metabolite level 0.3136733412201535 0.4956498725156859 0.6201414594738064 1.0 1.0 61 Q96CU9,Q86Y39,Q9HC21,Q96I36,P03886,P00403,Q9P0J0,P00846,P13073,Q9NPL8,O43676,Q7KZN9,O96000 13 +Limited wrist movement 0.4513069350532163 0.4943832339663452 0.6210355524426903 1.0 1.0 6 O75844 1 +Lower limb hyperreflexia 0.3223725713545726 0.4939620723256793 0.6213329655305868 1.0 1.0 21 O00400,P13073,Q14739 3 +Abnormalities of placenta or umbilical cord 0.3376415812329177 0.492391125106601 0.6224428720027522 1.0 1.0 16 O75844,P16435,P02545,Q01082,Q12768,P16278 6 +Abnormal atrioventricular valve morphology 0.2922600913203049 0.4908587083994531 0.6235263834209142 1.0 1.0 41 P51812,O75844,Q9Y4P3,P36543,P21964,Q15233,P55795,P04062,P35250,P02545,P22413,Q9UBS4,Q06787,P53701,Q12768 15 +Abnormal thalamic mri signal intensity 0.3964344168219165 0.4893619394769057 0.6245854768057066 1.0 1.0 8 Q96RR1,Q9GZY8,Q969G3 3 +Typical absence seizure 0.3642288729656133 0.4871323296768627 0.6261645568862777 1.0 1.0 12 Q13510 1 +Narrow nasal ridge 0.4168654754623017 0.4868510802483296 0.626363868621189 1.0 1.0 7 O75844 1 +Macular purpura 0.3364886748447196 0.4847602312594539 0.6278464357606695 1.0 1.0 16 Q8NCH0,P04062,P38435 3 +Lower limb spasticity 0.3267367082075479 0.4845746058290647 0.627978130705114 1.0 1.0 93 P33897,P35637,Q9NZJ7,O75787,P00846,O00400,Q5XKP0,P04062,Q9BRK0,P21912,P07602,Q96CU9,P49902,Q6DKK2,O00754,O60313,Q8N0X7,Q9Y619,Q99720,O00429,Q5HYK3,Q9P0J0,Q7KZN9,Q9H6K4 24 +Abnormal morphology of the choroidal vasculature 0.6402149035182108 0.4799885417126296 0.6312355406426131 1.0 1.0 3 P04439 1 +Choroidal neovascularization 0.6402149035182108 0.4799885417126296 0.6312355406426131 1.0 1.0 3 P04439 1 +Hydrocephalus 0.3252782968021151 0.4796463927055701 0.6314788521578425 1.0 1.0 86 P23786,Q9H490,Q15392,Q86WC4,Q9H9S5,P07237,P04062,O95202,P30153,O75312,P21964,O00754,Q15125,O43505,Q96J42,Q6NUK1,P08236,P16435,Q10713,Q8TAA9,Q969G3,P40855,O96028 23 +Knee flexion contracture 0.2993196632269535 0.4795378349432593 0.6315560588973086 1.0 1.0 27 P23786,Q8TD16,P36543,P49902,Q86XL3,P21912,Q7LGA3,Q96AY3,P37268 9 +Hypohidrosis 0.3889452404634052 0.476459127934046 0.633747319016337 1.0 1.0 10 Q13586,P06280 2 +Midline defect of the nose 0.6427967296306807 0.4757288908400957 0.6342675355547542 1.0 1.0 2 P98172 1 +Alternating esotropia 0.6387228912035788 0.4751801254356644 0.6346585917137597 1.0 1.0 3 P51797 1 +Osteolysis involving bones of the feet 0.477065139949422 0.4742743347301251 0.6353042910162543 1.0 1.0 5 O75844 1 +Foot acroosteolysis 0.477065139949422 0.4742743347301251 0.6353042910162543 1.0 1.0 5 O75844 1 +Abnormal pattern of respiration 0.2333490059594949 0.4715173562795839 0.6372713282665914 1.0 1.0 202 P23786,O75880,Q86Y39,P35637,Q9NZJ7,Q7LG56,Q9UHX1,P00846,O76024,P06280,Q9H9S5,Q96A33,P04062,Q92804,Q13510,Q16134,P07602,Q9UID3,P51812,Q15165,P51114,Q96CU9,P10253,P51571,P03886,Q15643,O60313,P98175,P12235,O75844,Q9Y619,Q10713,Q9P0J0,Q99758,Q7KZN9 35 +Steroid resistant nephrotic syndrome 0.4761944070374466 0.4708314482424439 0.637761104948261 1.0 1.0 5 Q12769,Q8N1F7 2 +Hyperconvex fingernails 0.4455213908388422 0.4694919793951722 0.6387180165359108 1.0 1.0 6 P51812,O95202 2 +Aplasia hypoplasia involving the metacarpal bones 0.2969930470203287 0.4692449693208168 0.6388945453976616 1.0 1.0 29 P51812,Q9Y366,P16435,Q9NX62,Q15643,Q32P28,Q9BXW9,Q14739,Q7RTS9,Q9H173 10 +Vascular skin abnormality 0.3091598928627738 0.4686892526248634 0.6392917701258387 1.0 1.0 133 Q06136,P36543,P02545,Q8IZA0,P00846,P06280,P16278,P38435,P51648,Q8WVM7,P04062,Q13126,P49327,P00403,Q07954,P21912,P22413,Q86YV9,P22830,P51812,Q9C0B1,P21964,P03886,Q8NCH0,Q15125,Q9Y487,Q9NWM8,P53701,P49257,P10619,O75844,Q6NUK1,Q16625,Q13586,P01889,Q14108,Q14739 37 +Hyperkeratosis 0.3110566026343396 0.4679179082897941 0.6398432963501921 1.0 1.0 61 O75844,P51648,Q06136,P16615,P04062,P42167,P02545,P21912,P09493,P22413,O95721,P06280,O15269,Q9NWM8 14 +Contractures of the large joints 0.6359278059785723 0.4662171368043654 0.6410600842052838 1.0 1.0 3 O75431,P50542 2 +Abnormal aortic valve morphology 0.2934970432313062 0.4651604690825933 0.6418165453402058 1.0 1.0 44 P51812,Q6NUK1,Q9Y4P3,Q6PGP7,P61978,O75844,P21964,P04062,Q9BXW9,Q9UHX1,P02545,P01889,Q01082,Q9BUB7,P06280,P37268 16 +Chronic rhinitis 0.6394135889484123 0.4645298000872055 0.6422682141945508 1.0 1.0 2 P51798 1 +Increased total bilirubin 0.5096528877776059 0.4640980016392672 0.6425775334292718 1.0 1.0 4 P23786,P14314 2 +Decreased calvarial ossification 0.5096242903808348 0.4639934383398547 0.6426524467750476 1.0 1.0 4 O75844,P02545 2 +Fever 0.3250319836742628 0.4636403388902786 0.6429054482539807 1.0 1.0 95 P23786,P10253,Q13586,P03886,Q9NZJ7,Q13510,P00403,Q96D53,Q9NR77,P00846,Q9NZ08,Q14739,P07602,Q9HC07 14 +Aplasia hypoplasia of the cerebral white matter 0.4117059696291112 0.4626290506966564 0.6436302817570236 1.0 1.0 7 P03886,P00403 2 +Retinal atrophy 0.2936832480259388 0.4623869382008707 0.6438038644842501 1.0 1.0 32 P51648,P04062,P04439,Q7LGA3,Q9H9S5 5 +Abnormality of the diencephalon 0.2925611651333299 0.4619400434313854 0.6441243170442126 1.0 1.0 33 Q9Y4P3,Q13057,O43819,Q9UPT5,Q9GZY8,Q969G3,Q8N3U4,P35250,Q969Y2,Q96RR1,Q96KP1,Q9H9S5 12 +Abnormal mitral valve physiology 0.2893767869777862 0.4613388973070358 0.6445554821856674 1.0 1.0 41 P51812,O75844,Q9Y4P3,O43819,O00754,P04062,P49327,P35250,P02545,P01889,Q9NZ08,P53701,P06280,P09493 14 +Oligodactyly 0.4113495200451783 0.4609666294447435 0.6448225469954743 1.0 1.0 7 Q9UQE7,Q14683,Q9UBC2,O60885,O60216,Q15427 6 +Bruising susceptibility 0.2882798279422053 0.4582341265811372 0.6467842444315819 1.0 1.0 36 P38435,Q04656,P04062,P49327,Q9BXW9,Q13126,Q8NCH0,P22413,Q14108,Q9NWM8,Q86YV9,P49257,P51798 13 +Premature skin wrinkling 0.321690537050544 0.4576600958292947 0.6471966609590718 1.0 1.0 20 Q6NUK1,O75844,P36543,P22413,Q9UP83,Q9Y487 6 +Recurrent paroxysmal headache 0.3852978582948085 0.4576549243626396 0.6472003769292032 1.0 1.0 10 P03886,P00403 2 +Alkalosis 0.4424240143890584 0.4563005793049411 0.6481738474262237 1.0 1.0 6 Q9Y619 1 +Muscle fibrillation 0.3278431896734457 0.4537688149272645 0.6499952313138257 1.0 1.0 17 P51114,Q9BQT8,Q13510 3 +Meningioma 0.4097658862869899 0.4535984845718397 0.6501178444344959 1.0 1.0 7 P21912,Q969G3 2 +Dysuria 0.3891406841319517 0.4530277594853787 0.6505287526531165 1.0 1.0 8 Q8N0X7,O76024 2 +Multifocal epileptiform discharges 0.2951553798614212 0.452844388855035 0.650660797618273 1.0 1.0 29 Q96N66,Q6P1N0,Q9H936,Q01082,Q9NZ01,Q9UBX3,O75503,P55011 8 +Kyphosis 0.2710169669612899 0.4520135171538189 0.6512592446610408 1.0 1.0 163 Q8WXH0,P36543,Q8TD16,Q5KU26,Q32P28,Q9UHX1,P02545,Q9HC07,P16278,Q9H9S5,Q9Y4P3,P07237,P51648,P04062,Q9NR77,P21912,O95202,P51812,P50402,O00754,Q8NCH0,Q15125,Q9BT22,Q9Y487,Q9NWM8,Q7RTS9,Q8N0X7,O75844,Q8WTW3,P08236,Q5H8A4,P01889,Q14108,Q14739,Q7LGA3,Q96AY3,O96028,Q12768 38 +Muscle flaccidity 0.6312275127316427 0.4512795451862436 0.651788085318314 1.0 1.0 3 P13473 1 +Rieger anomaly 0.5061214739564956 0.4512408147694378 0.6518159961829804 1.0 1.0 4 O95202 1 +Patchy changes of bone mineral density 0.5060941980172384 0.4511419447161092 0.6518872485622424 1.0 1.0 4 Q14739 1 +Hemifacial spasm 0.5056444950253716 0.4495128326354621 0.6530617530091214 1.0 1.0 4 Q10713 1 +Decreased pulmonary function 0.5056444950253716 0.4495128326354621 0.6530617530091214 1.0 1.0 4 P08236 1 +Impaired distal proprioception 0.505631749603003 0.4494666873885485 0.6530950338568628 1.0 1.0 4 Q96RR1 1 +Abnormal subarachnoid space morphology 0.2955278707281616 0.4465408119293691 0.6552066390653697 1.0 1.0 27 P03886,P00403,Q01105 3 +Sporadic 0.294302055195851 0.445260062960603 0.6561318255388808 1.0 1.0 29 P51812,P04062,P21912,O95202,O96028,P42345 6 +Central adrenal insufficiency 0.4695259593679358 0.4446990062675828 0.6565372875565267 1.0 1.0 5 O00170,P35222,Q9NRG9,Q9NSE4 4 +Aplasia hypoplasia of the phalanges of the toes 0.6320834508034872 0.4406236817162213 0.6594854555145044 1.0 1.0 2 P02545 1 +Abnormality of facial soft tissue 0.3104501507921284 0.4405208962218551 0.659559881184844 1.0 1.0 129 P33897,O75381,O43707,Q6P1N0,P50570,Q7LG56,Q8N1F7,Q9UHX1,P28070,O75787,P02545,Q01082,Q96TA2,Q9H9S5,P51798,P07196,Q9Y4P3,O15020,P04062,Q13510,Q15043,P21912,P51812,P30153,P10253,O00754,Q96D53,O60313,Q96RR1,Q14203,Q9BQT8,P12235,O75844,P16435,Q03252,Q969G3,O00429,P40855,Q12768,Q8NFH4 40 +Drowsiness 0.4067147455831933 0.4394854038810907 0.6603098559124627 1.0 1.0 7 O00754,Q5H8A4 2 +Distal lower limb amyotrophy 0.3357340068230326 0.4373549781278578 0.6618539296478558 1.0 1.0 14 P07196,Q8TD16,O95140,Q92734,P02545,Q9NR77 6 +Somatic sensory dysfunction 0.3167322741562423 0.437060782759117 0.6620672675588515 1.0 1.0 119 P33897,Q13045,P50570,Q9NZJ7,Q7LG56,P02545,Q8N2K0,P00846,Q9NZ08,P29992,P05067,P06280,O00400,P07196,Q8TB36,O43819,O15020,Q9BRK0,P54802,P49327,Q71SY5,Q9NR77,Q06787,O94905,O14773,P07602,Q8IV08,P61978,Q8NCH0,Q96RL7,Q96RR1,Q8N0X7,Q9Y619,Q6PI48,Q04656,P20700,P01889,Q96BR5,O15460,P07686,Q13217,O15269,Q9H6K4,Q12768 44 +Myopathy 0.3206801579049961 0.4344054810986612 0.6639940182342685 1.0 1.0 109 Q8WXH0,P23786,Q86Y39,P13473,Q969X5,Q7LG56,P00846,O43676,O76024,Q9H9S5,P07196,Q9Y4P3,Q53H12,Q13126,P00403,P21912,Q07021,P51114,P15291,P50402,O00754,O14979,P03886,Q8NCH0,Q96RL7,P42167,O60313,Q9NWM8,Q9NWS8,P12235,Q03252,Q13586,O00429,P09493 34 +Cutaneous syndactyly 0.3677123803802068 0.4320937885671616 0.6656732489769774 1.0 1.0 11 Q9Y619 1 +Unilateral renal agenesis 0.30483549127347 0.4307623074933362 0.6666412089128899 1.0 1.0 23 Q7LGA3,P30153,Q9UHX1 3 +Metaphyseal spurs 0.628700310121226 0.429760535474593 0.6673698431672583 1.0 1.0 2 Q04656 1 +Absent tibia 0.628700310121226 0.429760535474593 0.6673698431672583 1.0 1.0 2 Q04656 1 +Hand muscle weakness 0.3441101772186759 0.4270255091734967 0.6693607478590149 1.0 1.0 13 P07196,Q9NR77 2 +Thick eyebrow 0.2955497029907255 0.4268881423992064 0.6694608025668076 1.0 1.0 49 P51812,Q6NUK1,Q8TAQ2,P08236,O00754,Q03164,Q9BSJ2,Q969G3,Q9UHX1,Q01082,P98175,P04066,O94905,Q9UM00,P15586 15 +Abnormality of the odontoid process 0.4038979012450157 0.4265558462354667 0.6697028634902173 1.0 1.0 7 Q7RTS9,P16278 2 +Lower limb muscle weakness 0.2943430049969636 0.4259645449018656 0.6701336813994558 1.0 1.0 48 P07196,P33897,O43819,Q969X5,Q969G3,Q13510,P02545,Q9NR77,P00846,Q14203,O00400,Q12768,Q8N0X7 13 +Bilateral tonic clonic seizure 0.3217169086736385 0.4255819807871344 0.6704124726974718 1.0 1.0 94 Q9NZJ7,P00846,Q01105,P04062,Q13510,P00403,O43292,Q9NQZ5,P07602,P51812,P27544,Q9HC21,P03886,Q96RL7,O00429,Q5H8A4,Q5HYK3,Q9Y320,Q14739 19 +Shyness 0.6228432982319553 0.4250691733682917 0.6707862492209242 1.0 1.0 3 Q06787 1 +Ambiguous genitalia 0.2932408086589662 0.4239295695095726 0.6716171785379152 1.0 1.0 26 P16435,Q15392,Q8TAA9,Q96J42 4 +Hyporeflexia of lower limbs 0.3660772768189431 0.4234335823272693 0.6719789474647391 1.0 1.0 11 Q13586,Q9NR77,O75787 3 +Abnormality of the autonomic nervous system 0.3075497646636765 0.4225255929781939 0.6726414241742606 1.0 1.0 62 P33897,Q96EK5,Q9NZJ7,Q9BXW9,O76024,P06280,P04062,Q06787,P07602,P21964,O43681,Q96RL7,Q96RR1,P42892,Q10713,Q04656,Q8N3U4,Q15067,P20700,P07686,Q6PJG6,O15269 22 +Gastrostomy tube feeding in infancy 0.2859788936291563 0.4224432332528509 0.6727015271080079 1.0 1.0 35 P30153,Q01105,P35637,Q99720,O00429,Q9UP83,P51797,Q9H490 8 +Raynaud phenomenon 0.3825281473689982 0.4206816937043988 0.6739875304902452 1.0 1.0 8 O75844 1 +Cerebral hemorrhage 0.3428009373932826 0.4194204532726607 0.6749088787766517 1.0 1.0 13 P05067,P23786,P21912 3 +Truncal titubation 0.6209813874788571 0.4193266091203733 0.6749774523354157 1.0 1.0 3 Q5T8D3,Q6PJG6 2 +Abnormal tendon morphology 0.2396762860571801 0.4164652606352601 0.6770695827242132 1.0 1.0 236 Q8WXH0,P23786,P33897,P36543,P35637,Q8TD16,Q969X5,P28070,P02545,P50897,Q8IZA0,Q5JTV8,Q15392,Q9H9S5,P37268,P07196,Q8TB36,Q9HD42,Q9UPT5,Q96A33,P04062,Q13510,Q15043,Q9NR77,P21912,Q53FT3,O75312,P49902,Q15022,P50402,Q96PU5,Q8NCH0,Q9HC21,O60313,Q9BT22,Q9BUB7,Q9UP83,P42892,Q7RTS9,Q8N0X7,O75844,Q8WTW3,Q9Y619,P16435,P08236,Q86XL3,Q13586,Q99720,P20700,Q7LGA3,Q96AY3,P15586,Q96AA3 53 +Pseudobulbar signs 0.3646344997619923 0.4158272767120301 0.6775363976428117 1.0 1.0 11 Q14203,P20700,O94905,P17900 4 +Abnormal urine protein level 0.3073820590267063 0.412458171633661 0.6800036331876707 1.0 1.0 63 Q9Y4P3,Q03252,O43707,O95470,Q5JRA6,P09601,P04062,P03886,P00403,Q8N1F7,Q96D53,P21912,Q14108,O95721,P06280,Q8NFH4 16 +Agnosia 0.3757304239316903 0.4092043589112074 0.6823896958134776 1.0 1.0 10 P05067,P33897 2 +Excessive salivation 0.288738881631046 0.4087184165400307 0.6827463169478072 1.0 1.0 31 P51812,Q03252,P55795,Q96RL7,O75787,Q9NR77,P15586,Q8N0X7 8 +Abnormality of the calf 0.309193097578516 0.4078186578545171 0.6834068146335617 1.0 1.0 66 Q9Y619,Q9Y4P3,P08236,O75312,Q9NX62,P16435,Q96HY6,O00754,Q32P28,Q13126,Q15643,Q9NR77,P22413,Q9UP83,Q7LGA3,Q7RTS9,P16278 17 +Dyspnea 0.3178176264267587 0.4068159478747137 0.6841431727069804 1.0 1.0 111 P23786,P35637,Q969X5,Q9NZJ7,Q7LG56,Q9UHX1,P02545,P00846,P06280,Q92804,P04062,Q13510,P22413,Q16134,P07602,Q15165,P10253,P51571,P03886,Q15643,Q96RR1,Q14203,P53701,P51970,P12235,O75844,Q9Y619,P01889,Q99758 29 +Craniofacial asymmetry 0.6168901873094812 0.4068110684254855 0.6841467567531694 1.0 1.0 3 O95202 1 +Axonal regeneration 0.4928961423267888 0.4041235880857411 0.6861218400967282 1.0 1.0 4 P07196 1 +Contractures of the joints of the lower limbs 0.3041079326260862 0.4040234150337644 0.6861955008516578 1.0 1.0 60 Q8WXH0,P23786,P33897,P36543,P35637,Q8TD16,Q969X5,Q8IZA0,Q5JTV8,Q9H9S5,P37268,P21912,P50402,P49902,Q9HC21,O60313,Q86XL3,Q99720,Q7LGA3,Q96AY3 20 +Abnormal heart valve morphology 0.3194981848860176 0.4035657228282614 0.6865320958865588 1.0 1.0 91 P36543,Q9BXW9,Q9UHX1,P02545,Q01082,P06280,P16278,P37268,P51798,Q9Y4P3,Q6PGP7,P04062,P22413,Q06787,Q6ZXV5,O95202,P10644,P51812,P61978,P21964,P55795,Q96PU5,Q8NCH0,Q9UBS4,Q9BUB7,P53701,O75844,Q6NUK1,P08236,Q15233,Q5H8A4,P35250,P01889,O96028,Q12768 35 +Fatigable weakness of swallowing muscles 0.3398938409107455 0.4026485752693907 0.6872067696801489 1.0 1.0 13 P35637,Q92804,Q9UQN3,Q14203,Q15165 5 +Abnormal hair laboratory examination 0.3784545031685677 0.4010582075121992 0.6883772693995467 1.0 1.0 8 P51797,Q6PGP7,P02545 3 +Narrow vertebral interpedicular distance 0.6145091232803032 0.3995931385457882 0.6894562110068811 1.0 1.0 3 Q96HY6 1 +Vertebral arch anomaly 0.6145091232803032 0.3995931385457882 0.6894562110068811 1.0 1.0 3 Q96HY6 1 +Myelopathy 0.4915300359013389 0.399354262328127 0.6896321899817126 1.0 1.0 4 P33897 1 +Abnormal conus terminalis morphology 0.3733927304379369 0.3983965811142695 0.6903378776720319 1.0 1.0 9 O95202,Q5H8A4 2 +Absent toe 0.2897638039320648 0.3971514068288283 0.691255813335909 1.0 1.0 27 Q7LGA3,O95202,Q5H8A4,Q9UHX1 4 +Gingival bleeding 0.3474066204272393 0.3928678298524877 0.6944171031252471 1.0 1.0 12 Q14108 1 +Metopic synostosis 0.6122446103645096 0.3927744132811566 0.6944861042760675 1.0 1.0 3 P61978 1 +Death in infancy 0.3096423293871811 0.3909388451506594 0.6958424400246674 1.0 1.0 69 Q9H267,O75381,P50570,Q9NZJ7,P02545,P16278,P04062,P07602,P51114,Q9HC21,Q15643,Q9BT22,Q9BUB7,Q9NWS8,Q6NUK1,P20674,O00429,Q15067,Q15904,Q99758,P40855,Q6PJG6,Q12768 23 +Hyperactive patellar reflex 0.3761459235464818 0.3900454504017008 0.6965029386823862 1.0 1.0 8 P13073 1 +Limb muscle weakness 0.3182701284342466 0.3869569247739481 0.6987880975709997 1.0 1.0 93 Q8WXH0,P33897,Q969X5,Q7LG56,P02545,P00846,O00400,P05023,P07196,Q8TB36,Q13126,Q13510,Q9NR77,P50402,Q9BTV4,Q96RL7,Q96RR1,Q9BQT8,Q7RTS9,Q8N0X7,P12235,Q99720,Q969G3,Q15067,Q14739,O15269,Q12768 27 +Abnormally ossified vertebrae 0.4879396587775824 0.3869109766362583 0.6988221146603095 1.0 1.0 4 Q14739 1 +Absent or minimally ossified vertebral bodies 0.4879396587775824 0.3869109766362583 0.6988221146603095 1.0 1.0 4 Q14739 1 +Abnormal spermatogenesis 0.3244139455595566 0.385958480400527 0.6995274186285405 1.0 1.0 15 P04062,Q13423 2 +Abnormality of endocrine pancreas physiology 0.4876082266459984 0.3857690855142008 0.6996676925927539 1.0 1.0 4 Q14739 1 +Tremor by anatomical site 0.2866536336074359 0.3835461118375354 0.7013148870822778 1.0 1.0 30 P07196,Q05086,P35637,O95140,Q99720,Q92734,Q96RL7,P20700,Q9NP58,Q01082,Q9NR77,O94905,Q9Y4W6 13 +Prominent veins on trunk 0.6091520543891498 0.3835357228411871 0.7013225884969243 1.0 1.0 3 Q9Y487 1 +Abnormal subcutaneous fat tissue distribution 0.6091520543891498 0.3835357228411871 0.7013225884969243 1.0 1.0 3 Q9Y487 1 +Abnormal cutaneous elastic fiber morphology 0.6091520543891498 0.3835357228411871 0.7013225884969243 1.0 1.0 3 Q9Y487 1 +Abnormal circulating apolipoprotein concentration 0.6091520543891498 0.3835357228411871 0.7013225884969243 1.0 1.0 3 Q9Y487 1 +Heterotaxy 0.4248115991435329 0.3832513007497319 0.7015334439251515 1.0 1.0 6 O95202,Q5H8A4 2 +Atelectasis 0.3267597399276836 0.3831456801096898 0.7016117513099371 1.0 1.0 14 Q13510,P21964 2 +Erectile dysfunction 0.3582954638643968 0.3828159670018444 0.701856221748042 1.0 1.0 11 P33897,Q06787,Q969G3 3 +Impotence 0.3582954638643968 0.3828159670018444 0.701856221748042 1.0 1.0 11 P33897,Q06787,Q969G3 3 +Congenital muscular dystrophy 0.6081619388815851 0.380595978178249 0.7035030660437904 1.0 1.0 3 Q9H9S5 1 +Upper extremity joint dislocation 0.3100863983033309 0.37461419425357 0.7079474150684821 1.0 1.0 20 Q96PU5,Q6ZXV5 2 +Adult onset 0.3103575429163565 0.3727952906265225 0.7093008081438685 1.0 1.0 73 Q9NZJ7,P02545,O76024,Q9Y5L0,P38435,P04062,Q71SY5,Q14566,P21912,P22413,Q06787,Q07021,O15118,Q9NQZ5,P07602,Q8IV08,Q9BTV4,O14979,Q96RR1,Q14203,Q9UBS4,P42345,P14314,P12235,Q13586,Q9Y6M1,Q969G3,P20700,Q12768 29 +Axonal degeneration regeneration 0.4495657863291082 0.3691834470055119 0.7119909931399984 1.0 1.0 5 O95140,Q8TB36,P02545 3 +Joint laxity 0.3119010454167508 0.3671142183993107 0.7135338219105307 1.0 1.0 77 Q9Y619,Q9Y487,P36543,Q96HY6,O00754,P55795,Q96A33,Q8NCH0,Q32P28,Q5H8A4,Q9UHX1,Q969G3,Q06787,Q96AY3,Q9HC07,P16278 16 +Abnormality of the liver 0.2580592798863081 0.3663521432206656 0.7141023252707888 1.0 1.0 332 P23786,O75381,Q86Y39,P09601,Q9NZJ7,Q7LG56,Q9UJW0,P00846,O43676,Q5XKP0,P00374,Q9HC07,P16278,Q9NVI7,Q8N511,Q86WC4,Q96A33,P04062,P54802,Q13510,P21912,Q16134,Q9NPL8,O15118,Q01844,P07602,O95202,P22830,Q96CU9,O75312,Q16836,P21964,P10253,O75845,O00754,P03886,Q9HC21,Q96RL7,Q96I36,Q9BT22,Q9BUB7,Q96J42,Q9UP83,Q9NWS8,O96000,P10619,P12235,Q9Y619,P08236,Q03252,Q16625,Q10713,Q96HY6,Q5H8A4,Q15904,Q14108,Q7KZN9,Q14739,P40855,O96028,P15586,Q96AA3 62 +Abnormal neuron morphology 0.2852095892303062 0.3657977591339505 0.7145159921230415 1.0 1.0 29 Q92804,Q99720,Q13510,P35637 4 +Spasticity 0.2598624728069816 0.3626412498774021 0.7168728919313421 1.0 1.0 343 Q96D71,P33897,O75381,Q8TD16,P35637,P36543,Q5KU26,Q9NZJ7,O75787,P50897,P00846,O00400,Q5XKP0,Q15392,Q9NVI7,P16278,Q86WC4,Q9H2C2,P07196,Q9H490,Q9Y4P3,P51648,Q01105,P17900,Q92804,P04062,Q9BRK0,Q13510,Q15043,O15020,O43292,P21912,Q6ZXV5,O15118,O75503,P07602,Q53FT3,Q15165,P51812,Q96CU9,O75746,P49902,Q6DKK2,O00754,Q15022,P03886,O60313,O43505,Q9UBX3,Q9Y487,Q9NP80,Q7RTS9,O60220,Q8N0X7,Q9Y619,Q96N66,Q16625,Q10713,Q86XL3,O00584,Q99720,O00429,Q9BSJ2,Q5HYK3,Q9P0J0,Q9Y320,Q7KZN9,P40855,Q9H6K4,Q9Y287,Q96AA3 71 +Sleep apnea 0.2854927216403886 0.3612180362731303 0.7179364601053049 1.0 1.0 27 P51812,Q96A33,Q9UID3 3 +Fasting hyperinsulinemia 0.4798382009956297 0.3593360365791555 0.7193437188030343 1.0 1.0 4 Q16836 1 +Intestinal pseudo obstruction 0.3652854378156725 0.3579076412185549 0.7204124321552663 1.0 1.0 10 P03886 1 +Paraplegia paraparesis 0.3140398897855528 0.3571001345970084 0.7210168437196316 1.0 1.0 85 Q9Y619,Q96CU9,P33897,P35637,Q6DKK2,P04062,Q5XKP0,Q13510,O60313,Q9P0J0,P00846,Q7KZN9,O00400,Q9H6K4 14 +Abnormality of the lymphatic system 0.2728795512154086 0.355062691824648 0.7225426256020588 1.0 1.0 158 Q9NZJ7,Q9NZ08,Q15392,Q86WC4,P16278,Q96A33,P04062,P54802,Q13510,O15118,Q01844,P07602,O95202,P21964,P10253,O75845,O00754,Q96RL7,Q9BT22,Q9UP83,Q96J42,P10619,P08236,Q16625,Q96HY6,Q13586,Q15904,Q14108,Q14739,O96028,P15586 31 +Gastrointestinal obstruction 0.3161956161462295 0.354781348017156 0.722753402719559 1.0 1.0 16 P21912,P33897,P42892 3 +Advanced eruption of teeth 0.3402270663962698 0.3541752610924052 0.7232075423086484 1.0 1.0 12 O75844 1 +Abnormal peripheral action potential amplitude 0.3645060782611701 0.3541527090231612 0.7232244424064231 1.0 1.0 10 Q96RL7 1 +Enlarged thorax 0.2993455005893122 0.3540998137164283 0.7232640816869089 1.0 1.0 22 O75844,Q15643,Q32P28,Q14739,Q7RTS9 5 +Abnormal upper motor neuron morphology 0.3524134264299124 0.3528143317905156 0.7242276386456548 1.0 1.0 11 Q99720 1 +Splanchnic vein thrombosis 0.6027628982238615 0.3503199447802762 0.726098598715639 1.0 1.0 2 P37287 1 +Sudden loss of visual acuity 0.6027628982238615 0.3503199447802762 0.726098598715639 1.0 1.0 2 O00170 1 +Retinal fold 0.6027628982238578 0.3503199447802641 0.7260985987156481 1.0 1.0 2 P52732 1 +Progressive visual field defects 0.602762898223848 0.3503199447802366 0.7260985987156687 1.0 1.0 2 O43395 1 +Babinski sign 0.3151857246663239 0.3495335862554006 0.7266887607189432 1.0 1.0 96 P33897,P35637,Q9NZJ7,O75787,O75027,P00846,O00400,P07196,Q9BRK0,Q15043,Q9NR77,P21912,O14773,P07602,P51812,P49902,Q6DKK2,O00754,O60313,O60220,Q8N0X7,Q99720,Q15067,P20700,Q13217,Q9H6K4 26 +Abnormal eyelid physiology 0.3672612399099973 0.3484360414977854 0.7275127391293981 1.0 1.0 8 Q9NQZ5 1 +Delayed puberty 0.2936499404593656 0.3443377533401411 0.730592295201423 1.0 1.0 55 O75844,Q13045,P04062,Q14108,O76024,P06280,Q15800,Q9NVI7 8 +Abnormal circulating protein concentration 0.2534967801041653 0.3440377437441612 0.7308179012886549 1.0 1.0 170 Q8WXH0,P23786,O43707,P36543,O14653,P13473,Q969X5,Q7LG56,P53985,Q8N1F7,Q5JTV8,O00400,Q5XKP0,Q9BPX6,Q9HC07,Q9H9S5,Q8N511,P07196,Q9Y4P3,O95470,Q9Y584,Q6ZXV5,Q07021,P15291,Q16836,P50402,P10253,O14979,Q96RL7,Q96D53,P42167,P50416,O43505,Q9BT22,Q9Y487,Q9NWM8,P12235,Q13586,P09493,P46020,Q8NFH4 41 +Skin pit 0.3293312505254595 0.3431377785135971 0.7314948113888566 1.0 1.0 13 P61978,P16615,Q8N3U4,Q07954,O96028,O95202 6 +Nail dysplasia 0.2775476130809484 0.3427998485195406 0.7317490399210356 1.0 1.0 35 P51812,Q9Y619,Q13586,P10321,O95202,O96028,P42892 7 +Hypoplastic aortic arch 0.4741732206129421 0.3404856242935268 0.7334908469459513 1.0 1.0 4 Q9UHX1 1 +Melanocytic nevus 0.319417799565562 0.3400877977619557 0.7337904106746704 1.0 1.0 14 Q15022,Q01082,P21912,Q96AY3 4 +Polycystic kidney dysplasia 0.3091892793230272 0.3400782127272602 0.7337976287144574 1.0 1.0 18 P23786,Q16134 2 +Increased serum lactate 0.310527330852068 0.3347051749964101 0.7378474973214431 1.0 1.0 115 Q86Y39,O14949,Q7LG56,P00846,Q5XKP0,Q9NVI7,Q53H12,Q9Y584,Q9P0J1,P00403,P21912,Q96CU9,O75208,P03886,Q96I36,P13073,Q9UBX3,Q9BUB7,Q9NP80,Q9NWS8,P12235,O00429,Q70HW3,Q9P0J0,Q7KZN9 25 +Abnormal platelet morphology 0.4123258869009126 0.3337216492986989 0.7385896114737747 1.0 1.0 6 Q86YV9,O75845 2 +Cavernous hemangioma 0.4720973555352111 0.333670347435213 0.7386283277162571 1.0 1.0 4 P21912 1 +Trichorrhexis nodosa 0.4718507730851197 0.332864138716897 0.7392368404023426 1.0 1.0 4 P51797 1 +Distal joint laxity 0.5965604736397054 0.3323970110839256 0.7395894951808781 1.0 1.0 2 Q02809 1 +Telangiectasia of the skin 0.2918489228873034 0.3310166765537018 0.7406318889241543 1.0 1.0 23 P06280,Q8IZA0,P22413,Q14739 4 +Curly eyelashes 0.4112334180073387 0.3294859535201086 0.7417884092635787 1.0 1.0 6 Q9UQE7,Q14683,Q8N3U4,O60885,O60216 5 +Weakness of facial musculature 0.2992881798404916 0.3290946305048532 0.7420841626456487 1.0 1.0 63 P51812,P07196,O75381,Q969G3,Q7LG56,Q13510,Q9UHX1,Q15043,O60313,O00429,P40855,Q9BQT8,Q9H9S5,P12235 14 +Gliosis 0.2822774499390262 0.3284640381142665 0.7425608307197968 1.0 1.0 46 P35637,O00754,P04062,P00846,Q7KZN9,Q16134 6 +Intestinal polyp 0.2957818609001268 0.3281068300729383 0.7428308899592619 1.0 1.0 22 P21912,P33897,P42892 3 +Dilatation of the cerebral artery 0.3589628659666877 0.3277555267821027 0.7430965159157836 1.0 1.0 10 P10253,Q01082,P38435,P10644 4 +Abnormality of the 1st metacarpal 0.3584745762711993 0.3270756130928705 0.7436106962326472 1.0 1.0 9 Q9UQE7,O60828,Q14683,Q15233,Q6KC79,Q9BXW9,O60885,O60216 8 +Periportal fibrosis 0.5940231181279939 0.3251912992284906 0.7450362933511703 1.0 1.0 2 P49748 1 +Motor seizure 0.3100466911554113 0.3240486172517017 0.7459012271143051 1.0 1.0 114 O14653,Q9NZJ7,P00846,Q5XKP0,P16278,Q01105,Q9UPT5,P04062,Q13510,O43292,P21912,O75503,P07602,P03886,P13073,Q9UBX3,Q9Y619,Q96N66,O00429,Q5HYK3,Q9Y320 21 +Increased muscle fatiguability 0.4367402546600781 0.323060280826462 0.746649590014741 1.0 1.0 5 Q13586,Q7LG56 2 +Abnormal urine carbohydrate level 0.3334153773220672 0.3184370550661103 0.7501534340877523 1.0 1.0 12 Q6PGP7,O00754,P10253,Q9UJS0,P16278 5 +Abnormal circulating free fatty acid concentration 0.4670772570934963 0.3173992261373128 0.7509406943351631 1.0 1.0 4 Q16836,P49748 2 +Acne 0.3039677313993408 0.3171680306982367 0.751116106354756 1.0 1.0 19 Q92542,P21964,P01889,Q9NZ08,P22413 5 +Perseveration 0.360225764443692 0.3164188186782063 0.7516846349455801 1.0 1.0 8 P61916,P35637,Q15233 3 +Abnormality of earlobe 0.2797548784483535 0.3161903946073685 0.7518579980396096 1.0 1.0 28 Q15392,P98175,Q7LGA3,P21964 4 +Abnormality of the lens 0.234623520211025 0.3154803504316131 0.7523969679932137 1.0 1.0 234 P23786,O75381,Q06136,Q7LG56,P04439,Q9NZ08,O76024,P06280,O00400,Q9NVI7,Q9H9S5,Q53H12,P00403,Q03518,P21912,Q16134,Q6ZXV5,P51812,P21964,O00754,O75845,P03886,Q9NW15,O60313,Q15125,O43505,Q9BUB7,Q96J42,Q15800,P08670,P12235,Q16625,Q10713,Q7LGA3,P40855,Q9H6K4,Q9Y287 37 +Osteopetrosis 0.4654223312389133 0.3121017731525699 0.7549631790160505 1.0 1.0 4 Q15392 1 +Mesomelia 0.3589914384689942 0.3108917763810492 0.7558828964099855 1.0 1.0 8 Q14739 1 +Abnormality of the skull base 0.298974060968483 0.3100180332870476 0.7565472429322968 1.0 1.0 65 Q8WTW3,P23786,P15291,Q10713,P36543,Q96AA3,O00754,Q969G3,Q9UHX1,Q15125,O43505,Q14739,Q9NPL8,Q9Y487,Q96J42,Q9H490,Q9H9S5,Q9UID3 18 +Limb dystonia 0.3053862125574975 0.3088386012665693 0.7574443039789198 1.0 1.0 17 Q99720,Q96RL7 2 +Periorbital fullness 0.2966755781814718 0.3066682796887914 0.7590958762548763 1.0 1.0 21 P51812,Q7LGA3 2 +Wide nasal ridge 0.4626571330234588 0.3033253560107551 0.7616419245586852 1.0 1.0 4 Q15022 1 +Abnormality of the antitragus 0.5808944928599996 0.3032944071117786 0.7616655080661012 1.0 1.0 3 Q92643 1 +Reduced forced vital capacity 0.4309874885724261 0.3030475685444584 0.761853610536654 1.0 1.0 5 Q9BQT8 1 +Papillary renal cell carcinoma 0.4309619361821218 0.3029596535782579 0.7619206092293396 1.0 1.0 5 Q92733 1 +Bilateral cryptorchidism 0.342299064863594 0.3027753649567011 0.7620610586468244 1.0 1.0 11 Q2M1P5,P36543,Q15233,P78318,P37268 5 +Decreased plasma carnitine 0.3301800832885985 0.3018180179538363 0.7627907946928585 1.0 1.0 12 P23786,Q16836 2 +Thickened nuchal skin fold 0.3042265136954112 0.3017063382126252 0.7628759361234096 1.0 1.0 17 Q15125,Q15643,O75381,P40855 4 +Ulnar deviation of the wrist 0.5800875589442411 0.3011197723344027 0.7633231642011424 1.0 1.0 3 P16278 1 +Abnormal iris pigmentation 0.2917508063365758 0.2991977924470778 0.7647891335658157 1.0 1.0 22 Q9Y4P3,O75381,Q05086,Q9Y4I1,P35250,P40855,P56589,Q86YV9,P10644 9 +Molar tooth sign on mri 0.429865423160088 0.2991952878517327 0.7647910444700385 1.0 1.0 5 Q96KP1,Q10713 2 +Abnormal odontoid tissue morphology 0.2837586505981948 0.2981631636921317 0.7655786349154887 1.0 1.0 50 P07237,Q9Y4P3,P51648,Q6P4Q7,P21964,Q5JRA6,Q13586,Q15643,Q96AY3,P53701,Q9HC07,P16278 12 +Flat acetabular roof 0.3742539397800924 0.2971243247451089 0.7663715940428704 1.0 1.0 7 Q8WTW3,Q15643,Q7RTS9 3 +Fatigue 0.3091189172742342 0.2922765762755868 0.7700751667100958 1.0 1.0 89 P33897,P35637,Q9NZJ7,Q7LG56,Q9NZ08,P06280,Q53H12,Q92804,P04062,P49327,P21912,Q07021,P07602,Q15165,Q13423,O60313,P50416,Q96RR1,Q14203,Q9NP80,P12235,O00429,Q70HW3,P01889,O15460,Q14739 26 +Adrenal hypoplasia 0.3544254232491443 0.2906903250819609 0.7712881716991493 1.0 1.0 8 O75844,Q12768 2 +Neoplasm of the male external genitalia 0.3500492832761912 0.2885409262115865 0.7729327073636749 1.0 1.0 9 Q13423 1 +Increased adipose tissue 0.457876797855274 0.2883787939823179 0.773056798508345 1.0 1.0 4 O75431,P02545 2 +Restrictive ventilatory defect 0.3190943410366489 0.2878355400703309 0.7734726310297506 1.0 1.0 13 Q9H9S5,P16278 2 +Syringomyelia 0.4572637517630335 0.2864830219822994 0.7745081952893353 1.0 1.0 4 Q93063,Q9Y2U8,P35222 3 +Kyphoscoliosis 0.2913653528565254 0.2840845214268008 0.7763456086227924 1.0 1.0 59 P51812,O75844,Q8WTW3,P36543,Q5KU26,Q8NCH0,P02545,Q9NR77,Q9HC07,Q9Y487,Q9NWM8,Q9H9S5,Q8N0X7,Q96AY3 14 +Abnormality of the vertebral endplates 0.3485671116484226 0.2819038702370672 0.7780172218270502 1.0 1.0 9 P22413,P51798,Q7RTS9 3 +Anorexia 0.27478722733884 0.2818554610389964 0.7780543423654742 1.0 1.0 30 Q14108,P04062,Q9NZ08,Q13423 4 +Abnormal shoulder physiology 0.5725938878531053 0.2812525706643988 0.7785166856622161 1.0 1.0 3 O75844 1 +Rib fusion 0.3260738299223992 0.2810728459068974 0.7786545277815533 1.0 1.0 12 Q8WTW3,O96028,O95202,Q5H8A4 4 +Abnormal cochlea morphology 0.572516308499904 0.2810500247360307 0.778672031258328 1.0 1.0 3 O60220 1 +Follicular hyperkeratosis 0.3701019157850072 0.2800914910234874 0.7794073127230101 1.0 1.0 7 Q9NWM8 1 +Abnormal cerebral artery morphology 0.3036296472276311 0.2792188932812264 0.7800768452702358 1.0 1.0 16 P05067,P10253 2 +Nasal regurgitation 0.5771074147166744 0.2790997900064097 0.7801682442805329 1.0 1.0 2 P53007 1 +Abnormality of the knee 0.3089523696350516 0.2784867200275254 0.780638757888453 1.0 1.0 98 P23786,P36543,Q8TD16,P16278,P37268,Q9Y4P3,Q13510,Q9NR77,P21912,P22413,Q6ZXV5,Q9NX62,O75312,P49902,P21964,O00754,Q96PU5,Q15643,Q15125,Q9UP83,Q7RTS9,Q8N0X7,Q9Y619,P08236,Q96HY6,Q5JRA6,Q7LGA3,Q96AY3 28 +Impaired pain sensation 0.2887460274132507 0.2780097420177713 0.7810048803926275 1.0 1.0 22 Q13045,Q9NR77,P07196 3 +Abnormal elasticity of skin 0.298667029638324 0.2776988618728536 0.7812435343412234 1.0 1.0 69 P51812,Q6NUK1,Q9Y4P3,O75844,P36543,O00754,P04062,Q13126,Q8NCH0,Q9UHX1,O75787,Q15904,P22413,Q9Y487,Q9NWM8,O96000,P38435 17 +Abnormal anatomic location of the heart 0.3170192853834378 0.2769383605173001 0.7818274366639304 1.0 1.0 13 O75844,Q10713,Q96J42 3 +Abnormal muscle fiber type distribution 0.3168909379047169 0.2762679744060661 0.7823422517632541 1.0 1.0 13 P51797,P51114 2 +Azoospermia 0.316846481461335 0.2760358684747357 0.7825205170064462 1.0 1.0 13 Q13423 1 +Papilloma 0.3463699348507478 0.2699478290575774 0.7872003903136975 1.0 1.0 10 P21912 1 +Distal upper limb amyotrophy 0.3066104200864192 0.2681572203722197 0.7885783025792958 1.0 1.0 14 P07196,Q8TB36,Q9NR77,Q9BQT8 4 +Thick cerebral cortex 0.4204597366521829 0.2675856059009605 0.789018311873805 1.0 1.0 5 Q9Y487 1 +Severe global developmental delay 0.3023040564453308 0.2663878050420176 0.7899405561944601 1.0 1.0 77 P51812,O75312,O75381,Q96A33,P03886,O00584,Q5H8A4,Q9HC21,Q9BT22,P00846,Q7LGA3,P40855,Q9H490,Q7RTS9,Q9UID3 15 +Dilated fourth ventricle 0.2758523302206825 0.2663854047921866 0.7899424045577954 1.0 1.0 46 P23786,P15291,Q10713,Q12768,P36543,Q969G3,Q15125,O43505,Q9Y487,Q96J42,Q9H9S5,Q9UID3 12 +Exercise induced muscle cramps 0.3942645649370331 0.265904084428836 0.7903130793881799 1.0 1.0 6 P23786,P13473 2 +Ophthalmoparesis 0.3036047054846035 0.2652366492466062 0.7908271636063007 1.0 1.0 80 Q7LG56,P00846,O76024,Q9BPX6,P04062,P00403,P21912,Q07021,Q96CU9,P03886,O60313,P12235,Q10713,Q13586,Q969G3,O00429,P01889,Q9P0J0,O15460,Q7KZN9 20 +Fatty replacement of skeletal muscle 0.3484486847317219 0.2648506938775921 0.7911244828054032 1.0 1.0 8 P51114 1 +Abnormality of the upper respiratory tract 0.3076034619916372 0.2637487416391244 0.7919735345039278 1.0 1.0 101 P36543,P35637,Q9NZJ7,Q9UHX1,P28070,P16278,Q92804,P54802,Q13510,Q03518,Q06787,Q86YV9,P07602,Q15165,P21964,O00754,Q7RTS9,P08236,P16435,Q96HY6,Q969G3,P01889,O15460,Q14739,P15586 25 +Hypoplasia of teeth 0.2865473527651726 0.262710970097005 0.7927733607984826 1.0 1.0 22 P51648 1 +Saccadic oscillation 0.5645521139167614 0.2606057784768335 0.7943965330539193 1.0 1.0 3 P04062 1 +Opsoclonus 0.5645521139167614 0.2606057784768335 0.7943965330539193 1.0 1.0 3 P04062 1 +Aplasia hypoplasia involving the skeletal musculature 0.3333617579401505 0.2603489923707979 0.7945945847081779 1.0 1.0 11 Q9NR77,O43505,Q9H9S5 3 +Broad toe 0.2708879290638597 0.2589690881543253 0.7956590911461083 1.0 1.0 32 Q7LGA3,P30153,Q9UHX1 3 +Cirrhosis 0.270095991569052 0.2589521451880294 0.7956721639120015 1.0 1.0 42 P22830,Q10713,P04062,Q7LG56,Q15904,Q14739,Q14108 7 +Short thorax 0.3643951403033649 0.2571760402461638 0.7970428792093067 1.0 1.0 7 Q15643,Q7RTS9 2 +Abnormal metabolism 0.2846803971747106 0.2561248726433453 0.7978544167964354 1.0 1.0 55 Q8N511,Q9Y487,P33897,P36543,P51571,O75787,Q9BT22,Q15904,O14678,P46977,P22413,Q9UP83,Q96AA3 13 +Dystonia 0.2290066468234576 0.2555409507266266 0.7983053190865357 1.0 1.0 181 P35637,Q9NZJ7,O14949,P00846,P16278,Q9H2C2,Q01105,P17900,P04062,Q9NQZ5,O15118,P07602,Q96CU9,O75208,Q6DKK2,P03886,Q96RL7,O60220,O00584,Q99720,Q9P0J0,Q7KZN9 22 +Suicidal ideation 0.5621970931133431 0.2546945563994193 0.7989590209911328 1.0 1.0 3 Q14203 1 +Upgaze palsy 0.4162157367361195 0.2537349814626892 0.7997003069418545 1.0 1.0 5 Q96RL7 1 +Episodic tachypnea 0.345446238512685 0.2521391119701198 0.8009335393511563 1.0 1.0 8 P22695,Q10713,P49748 3 +Chorioretinal coloboma 0.3453591883943283 0.2517733215187152 0.8012162795093241 1.0 1.0 8 Q01082,Q10713,Q12768 3 +Cerebral hamartoma 0.4454160789844698 0.2508155690394562 0.801956703908824 1.0 1.0 4 Q2M1P5,P49815,Q9H269 3 +Abnormal cartilage morphology 0.3009537364643991 0.2491803066686338 0.8032213120714853 1.0 1.0 15 Q9UHX1 1 +J shaped sella turcica 0.4447491762154444 0.2488640125747098 0.8034659734395264 1.0 1.0 4 P08236 1 +Pharyngitis 0.4443610777498816 0.2477311377449065 0.8043424382295117 1.0 1.0 4 P01889 1 +Lissencephaly 0.2892492923834115 0.245991487382084 0.8056888221581078 1.0 1.0 61 P23786,P36543,O95721,Q15392,Q9H9S5,Q15058,Q16134,Q6ZXV5,Q9C0B1,Q9HC21,O43505,Q9Y487,Q9NWS8,Q16625,Q86XL3,Q9BSJ2,P20700,Q9Y320,P62258 19 +Mortality aging 0.301134233828946 0.2457183563131567 0.8059002614896988 1.0 1.0 120 Q9H267,Q6NUQ1,O75381,Q96IX5,P50570,Q9NZJ7,P02545,P05067,O95721,Q9NVI7,Q86WC4,P16278,Q9H9S5,Q9Y4P3,O43819,P04062,Q16134,Q9NPL8,P07602,P51812,P51114,Q9Y276,Q9HC21,Q15643,Q9BT22,Q9BUB7,Q9NWS8,O96000,O75844,Q6NUK1,P16435,Q04656,P20674,O00429,Q15067,P35250,O75718,Q15904,Q99758,Q14739,P07686,P40855,Q6PJG6,Q12768,Q9NX14 45 +Absent septum pellucidum 0.2657163406042693 0.2450066280516731 0.8064512993036055 1.0 1.0 36 Q96N66,Q6P1N0,P51571,Q8N3U4,Q9NZ01,O43505,O95202,P53701,O96028,Q15392,Q9H9S5,P55011,Q9NX14 13 +Inflammatory abnormality of the eye 0.2659482849989236 0.2446401233438893 0.8067350939118021 1.0 1.0 40 P51648,P49327,P28070,P01889,P04439,Q9NZ08,Q14739,Q15800 8 +Metaphyseal widening 0.2710087218338058 0.2443309826435784 0.8069744897873945 1.0 1.0 27 Q96HY6,Q14739,Q7RTS9,Q86WC4,P16278 5 +Abnormal circulating follicle stimulating hormone concentration 0.3609999028981554 0.2438249450273287 0.8073663999427678 1.0 1.0 7 P16435 1 +Gait imbalance 0.2795027346482787 0.2413712156962701 0.8092674198589136 1.0 1.0 23 Q9Y4P3,Q05086,Q7LG56,Q5H8A4,Q9UBB4,Q9NR77,O94905,O15269 8 +Mutism 0.294004245625962 0.2405912093158043 0.8098719640378511 1.0 1.0 17 Q13510 1 +Hepatic necrosis 0.3422130698357789 0.2386592863037978 0.8113697893394756 1.0 1.0 8 Q16134 1 +Abnormality of the umbilical cord 0.3386256396359383 0.2385566205979987 0.8114494057237591 1.0 1.0 9 O75844,P16435,Q12768 3 +Vitreous hemorrhage 0.4113995485327353 0.238339656051223 0.8116176663038073 1.0 1.0 5 P29992,P35222,O75533,Q99496 4 +Hypoplastic nipples 0.3166821984375137 0.2351793227566043 0.8140695540135092 1.0 1.0 12 Q6NUK1,Q96A33 2 +Bilateral talipes equinovarus 0.3586002293154265 0.2345197648598204 0.8145814908408497 1.0 1.0 7 Q15125,Q15392 2 +Hepatic fibrosis 0.2672302579218153 0.2339986911895579 0.8149859947404992 1.0 1.0 33 P04062,Q13510,Q96J42 3 +Abnormality of dental color 0.5537082199621788 0.2339070058668027 0.8150571741787866 1.0 1.0 3 P16278 1 +Squamous cell carcinoma of the skin 0.409706546275393 0.2330110822816229 0.815752800191627 1.0 1.0 5 Q92889,P19447,P18074,P02545 4 +Joint contracture of the hand 0.2832406968538183 0.2328117456106322 0.8159075918373744 1.0 1.0 56 O75844,P07196,Q9Y619,Q9NR77,Q8IZA0,P42892,Q9BUB7,Q15392 8 +Scapular winging 0.2695104103972184 0.2327360423694078 0.8159663798390235 1.0 1.0 27 Q8WXH0,P07196,Q8TD16,P50402,O00429,P02545,O60313,Q9Y487 8 +Intestinal hypoplasia 0.4360883018590223 0.2240830957018056 0.8226926457204073 1.0 1.0 4 O75844 1 +Abnormal circulating sex hormone concentration 0.2873216919319533 0.2228624234970165 0.8236425825856537 1.0 1.0 20 P16435,Q13423 2 +Abnormality of the glabella 0.3819074699839815 0.2224294419893775 0.8239795944224657 1.0 1.0 6 O96028,O95202 2 +Aplasia hypoplasia of the proximal phalanges of the hand 0.5480997301288575 0.2206278055519938 0.8253822488161005 1.0 1.0 3 P42345 1 +Renal duplication 0.3373371817451044 0.2187525711856659 0.8268427947095485 1.0 1.0 8 Q9Y4P3,Q9BXW9 2 +Recurrent fever 0.2901779905961278 0.2185798804272705 0.8269773269206702 1.0 1.0 17 Q9NR77,Q13510 2 +Kinetic tremor 0.2616968192889519 0.2177988305609808 0.8275858557705691 1.0 1.0 39 O15020,Q9NZJ7,Q9NW15,Q9UBB4,P20700,O75027,Q14108,Q06787,Q9BUB7,P07602,Q9Y287 11 +Progressive microcephaly 0.2729175198688802 0.2165798326314879 0.828535803932229 1.0 1.0 48 Q8WTW3,P36543,Q6P1N0,Q5KU26,Q9HC21,Q9BSJ2,Q6PJG6,Q15043,P50897,Q9BT22,Q9Y487,O95721 12 +Focal myoclonic seizure 0.3535299479087904 0.2152258423900695 0.8295912437027266 1.0 1.0 7 O75503 1 +Abnormal temper tantrums 0.336275340344123 0.214486378575899 0.8301677881294878 1.0 1.0 8 P04062 1 +Decreased circulating antibody level 0.2726763359119071 0.2143420060796881 0.8302803630164926 1.0 1.0 48 P02786,O00754,P09601,Q9UJS0,P49327,Q9UJW0,O75787,Q15904,P42345,O60220 10 +Cerebellar dysplasia 0.3779026427019059 0.2088924024057598 0.8345322353306419 1.0 1.0 6 Q9H9S5 1 +Difficulty standing 0.3777317576783879 0.2083210149425614 0.8349783240274202 1.0 1.0 6 O43292 1 +Tracheal stenosis 0.3777098669681815 0.208247856263822 0.8350354436783916 1.0 1.0 6 Q96HY6 1 +Motor delay 0.232810282048696 0.2070251763927351 0.8359901964896843 1.0 1.0 247 Q96D71,P36543,Q6P1N0,P35637,P50570,Q03164,Q5KU26,Q8TD16,P02545,P11233,O75787,Q9NZ01,Q01082,Q9UM00,Q5XKP0,Q9BPX6,Q9H9S5,P55011,P51798,P07196,Q8TB36,Q01105,O43819,Q53H12,P04062,Q13510,Q15058,P00403,Q9NR77,P21912,Q06787,Q6ZXV5,O94905,Q9UID3,P51812,P51114,P61978,Q05086,P30153,Q16836,P49902,P10253,O00754,P03886,Q8NCH0,Q15643,O75569,O60313,Q9P2J5,Q9UP83,Q9Y487,Q9NWM8,P51970,Q7RTS9,Q8N0X7,Q8WTW3,Q9Y366,Q96N66,P16435,Q03252,Q10713,Q99720,Q5H8A4,P20700,Q8N6M0,Q7LGA3,Q6PJG6,P51797 68 +Sudden death 0.2654904569372607 0.2062713365623615 0.8365789671830133 1.0 1.0 30 Q8WXH0,Q9Y4P3,P50402,P02545,P01889,P50416,O15460,P22413 8 +Abnormality of the bladder 0.2858399128643163 0.2053819479646622 0.8372737230895355 1.0 1.0 138 P33897,P35637,P50570,Q9NZJ7,Q9UJS0,Q7LG56,Q9UHX1,O76024,P07196,Q9Y4P3,P04062,Q9BRK0,Q15058,Q9UBB4,Q9NR77,P21912,Q06787,O94905,P07602,P51812,P61978,P21964,O43681,Q8NCH0,Q96RR1,Q9UP83,Q9NWM8,P22626,Q8N0X7,P12235,P16435,Q6PI48,Q04656,Q8TAA9,Q86XL3,Q99720,Q969G3,P35250,P20700,P01889,P51797,Q12768 42 +Vertical supranuclear gaze palsy 0.3026033588420496 0.2044500130112853 0.8380018507225417 1.0 1.0 13 O15118,Q96RR1,Q14203,Q96RL7 4 +Breathing dysregulation 0.4279120057537688 0.2016749632506975 0.8401708368401373 1.0 1.0 4 Q10713 1 +Enlarged posterior fossa 0.2807308973328118 0.1998438132766461 0.8416027343832861 1.0 1.0 57 Q8WTW3,P23786,P15291,Q10713,P36543,O00754,Q969G3,Q15125,O43505,Q9NPL8,Q9Y487,Q96J42,Q9H490,Q9H9S5,Q9UID3 15 +Abnormal cranial nerve physiology 0.29620235897526 0.1994727529895235 0.8418929550273317 1.0 1.0 78 O75381,P50570,Q9NZJ7,Q7LG56,Q9BXW9,Q9UHX1,P02545,Q9NZ08,Q96TA2,Q86WC4,Q9H9S5,P51798,P07196,P49327,Q13510,Q15043,Q9NR77,P21912,P07602,P51812,Q96RR1,Q14203,P12235,Q969G3,P01889,P40855 26 +Abnormal circulating glutamine family amino acid concentration 0.3490911241966979 0.198755924831885 0.8424536749364564 1.0 1.0 7 Q9P0J1,O96000,P20674 3 +Ectopia pupillae 0.3983254434009364 0.1983518966075715 0.8427697505760587 1.0 1.0 5 O95202 1 +Vertebral clefting 0.3283791676917272 0.1961519182626664 0.8444912605768666 1.0 1.0 9 Q8WTW3,Q15643,Q8N3U4,O75845 4 +Schistocytosis 0.4255315564723353 0.195336083504554 0.8451298505608924 1.0 1.0 4 O75845 1 +Akinesia 0.3179684075840074 0.191691934930861 0.8479835238266338 1.0 1.0 11 P04062 1 +Abnormality of the gingiva 0.2757496557619512 0.1913107638903911 0.8482821284766224 1.0 1.0 53 Q9Y4P3,P08236,O75845,O00754,Q5JRA6,P04062,Q14739,Q14108,P49257,Q15392,Q86WC4,P16278 12 +Type i transferrin isoform profile 0.327888142770991 0.1912296984230843 0.848345636964416 1.0 1.0 10 P51571 1 +Arterial stenosis 0.2851133625158652 0.1902260072369136 0.8491320323644571 1.0 1.0 17 Q9Y4P3,Q04656,P02545,P01889,P21912,P22413 6 +Epiphora 0.3951245372961561 0.1889788751415304 0.8501093736516527 1.0 1.0 5 Q15043 1 +Episodic pain 0.2887892274442788 0.1845395767315667 0.8535901825151018 1.0 1.0 15 Q13423 1 +Cortical dysplasia 0.2605589283871469 0.1842764640992977 0.8537965766641664 1.0 1.0 34 Q96N66,Q6P1N0,Q96PU5,Q9NZ01,O43505,O95721,P42345 7 +Hypoplasia of the radius 0.3248821944199652 0.1822428031488575 0.8553921833430604 1.0 1.0 9 Q15643,P98175 2 +Generalized lipodystrophy 0.420409488282163 0.1819852860909717 0.8555942730806378 1.0 1.0 4 O75844 1 +Metaphyseal dysplasia 0.2976048794979704 0.1807283304634778 0.8565808204534233 1.0 1.0 13 Q9HC07 1 +Tetraplegia 0.2895371057528433 0.1795864374342196 0.8574772529283816 1.0 1.0 14 O43681,Q92734,Q13423,P51572,P51970 5 +Thin clavicles 0.5286888876627167 0.1775542754358456 0.859073036758109 1.0 1.0 3 O75844 1 +Depression 0.2986335537661203 0.1755862561077767 0.8606190006303971 1.0 1.0 110 Q6P1N0,P35637,Q9NZJ7,Q7LG56,Q01082,P50897,Q9NZ01,O76024,P06280,P55011,Q9Y4P3,Q92804,P04062,P00403,Q9UBB4,Q06787,P07602,P10644,P51812,Q15165,P21964,Q6DKK2,O00754,Q9Y276,P03886,O43681,Q96RL7,Q96RR1,Q14203,P12235,Q96N66,Q8N3U4,P20700,P01889,O15460 35 +Supravalvular aortic stenosis 0.3256142332674288 0.1730787117614986 0.8625895579616458 1.0 1.0 8 Q9Y4P3,P62070,Q9UIG0,P35250,Q15056,P01130,O43709 7 +Aortic arch aneurysm 0.3256142332674285 0.1730787117614972 0.8625895579616469 1.0 1.0 8 Q9Y4P3,O95155,Q9UIG0,P35250,Q15056,Q96T58,O43709 7 +Bowel diverticulosis 0.3256142332674259 0.1730787117614873 0.8625895579616547 1.0 1.0 8 P54886,Q9Y4P3,Q9UIG0,P35250,P43246,Q15056,O43709 7 +Decreased specific antibody response to protein vaccine 0.5308711587257 0.1717297031791286 0.8636500329475167 1.0 1.0 2 Q13546 1 +Bundle branch block 0.2861061567585503 0.1709473255583581 0.8642651839033633 1.0 1.0 15 P06280,Q9HD47,P36543 3 +Abnormality of the abdominal organs 0.2586466813604982 0.1707737083485694 0.8644017030563973 1.0 1.0 388 O75880,O43707,P09601,Q9UHX1,Q8N1F7,O75787,P00846,O43676,P00374,Q9HC07,Q8N511,Q9Y4P3,Q13510,P22413,P21953,Q16134,P07602,P22830,Q96CU9,P10253,P03886,P10619,Q14108,Q7KZN9,P23786,Q86Y39,Q9NZ08,Q5XKP0,Q15392,P16278,Q96A33,P04062,P54802,P00403,P21964,Q8NCH0,Q96RL7,Q96D53,Q96J42,P12235,Q9Y619,Q96HY6,Q13586,Q15904,Q14739,P40855,P15586,Q9NZJ7,Q9UJW0,O76024,Q9NVI7,Q86WC4,Q9NPL8,O15118,O95202,O75312,Q9BT22,Q9BUB7,O96000,Q16625,Q5H8A4,O96028,Q96AA3,O75381,Q7LG56,P21912,Q01844,Q16836,O75845,O00754,Q9HC21,Q96I36,Q9UP83,Q9NWS8,P08236,Q03252,Q10713,Q969G3 78 +Abnormal lateral ventricle morphology 0.259481745865007 0.1698270955570419 0.8651461172770969 1.0 1.0 33 Q01105,Q96RL7,Q8N3U4,Q969M3,Q5H8A4,O75787,Q9UP83,Q9NX14,P53701,Q9UID3 10 +Abnormality of the phalanges of the toes 0.2785709498764263 0.1694050043030419 0.8654780875316934 1.0 1.0 20 O75844 1 +Cataplexy 0.4150020498885494 0.1683249354784596 0.8663276580554791 1.0 1.0 4 O15118 1 +Hyperorality 0.387566598994283 0.1675233720644807 0.8669582591284859 1.0 1.0 5 Q14203,Q05086 2 +Abnormality of the pharynx 0.269739408748888 0.1664788824932507 0.8677801005934067 1.0 1.0 50 P08236,P21964,Q969G3,P54802,Q13510,P01889,Q03518,Q86YV9,Q7RTS9,P15586,P16278 11 +2 3 toe syndactyly 0.2603733858495798 0.1664619729253868 0.8677934068195028 1.0 1.0 30 P51812,Q96PU5,Q9UHX1,P11233,Q15125 5 +Cerebral cortical atrophy 0.2949866940423793 0.1661267164513972 0.8680572295945739 1.0 1.0 119 Q8TD16,Q5KU26,P00846,O76024,P05067,Q9H9S5,Q9UGJ1,Q9UPT5,P04062,P00403,Q06787,O75503,P51812,O00754,P03886,Q96RL7,Q9BUB7,Q9Y619,Q16625,Q7LGA3,Q96AA3 21 +Fatigable weakness of bulbar muscles 0.2851194958503457 0.1660126310023539 0.8681470100044959 1.0 1.0 15 Q92804,P35637 2 +Upper limb amyotrophy 0.2804766442018008 0.1650882688905543 0.8688745063878858 1.0 1.0 17 P07196,Q8TB36,Q9NR77,Q9BQT8 4 +Abnormality of the parathyroid gland 0.268052671962691 0.1637367519417013 0.8699383841126074 1.0 1.0 23 P03886,P00403 2 +Aplasia hypoplasia of the breasts 0.3227340752647471 0.1623526330797962 0.8710281692118687 1.0 1.0 8 P02545,Q9Y619,P82650,P57740 4 +Abnormality of the phalanges of the hallux 0.5209030435167514 0.161567554347818 0.8716464094363223 1.0 1.0 3 Q2M1P5 1 +Agitation 0.2576298473828169 0.1601537542751949 0.8727599578184804 1.0 1.0 34 P35637,Q92804,P04062,Q01082,Q14203,P10644,Q6PJG6,P05067,P42892,Q15165 10 +Abnormal tricuspid valve morphology 0.2931122341832005 0.1600749054109994 0.8728220688277701 1.0 1.0 13 P51812,Q15233,P21964,P53701,Q12768,Q9NX14 6 +Premature loss of teeth 0.2926746880124782 0.1580981587543436 0.8743794514672021 1.0 1.0 13 O75844,P02545,Q5JRA6 3 +Pulmonary interstitial high resolution computed tomography abnormality 0.3838791078483848 0.1574070713952086 0.8749240407626087 1.0 1.0 5 Q13510 1 +Epidermoid cyst 0.5180485053581673 0.1558948040725799 0.876115940984971 1.0 1.0 3 O60716,P49815 2 +Subcutaneous hemorrhage 0.2638325052190679 0.1557239291437272 0.8762506345413552 1.0 1.0 46 P38435,Q16625,Q04656,P21964,Q13586,P04062,P49327,Q9BXW9,Q13126,Q8NCH0,P22413,Q14108,Q9NWM8,Q86YV9,P49257,P51798 16 +Temporal cortical atrophy 0.4097368252061907 0.1554596551812337 0.8764589577045911 1.0 1.0 4 Q9UQN3,Q8WTW3 2 +Myelomeningocele 0.4084605556874434 0.1524066495618174 0.8788662127543421 1.0 1.0 4 Q8TAA9 1 +Irregular epiphyses 0.3359425036777074 0.1523967944982207 0.8788739851691232 1.0 1.0 7 Q7RTS9 1 +Specific learning disability 0.2895221352525662 0.1502161993142419 0.8805940457049855 1.0 1.0 75 P33897,P35637,Q01082,Q9BPX6,Q9H9S5,P00403,Q06787,P10644,O75845,O00754,P21964,P03886,Q96RR1,O43505,P53701,P42345,P22626,Q8N0X7,Q9H173,Q9Y619,Q10713,Q6PI48,Q04656,Q13586,Q8N3U4,Q9H6K4,Q9NX14 27 +Dilation of lateral ventricles 0.2578128033495516 0.1491613534650388 0.8814263142489063 1.0 1.0 25 Q9UP83,Q96RL7,Q01105,Q9UID3 4 +Nonimmune hydrops fetalis 0.2579989719409944 0.1472170499137538 0.8829607033394136 1.0 1.0 29 Q9BT22,P04062,Q14739,P10619 4 +Limb joint contracture 0.2948013568641568 0.1470125329139387 0.8831221279724819 1.0 1.0 115 Q8WXH0,P23786,P33897,P36543,P35637,Q8TD16,Q969X5,Q8IZA0,Q5JTV8,Q15392,Q9H9S5,P37268,P07196,Q9NR77,P21912,P49902,Q15022,P50402,Q9HC21,O60313,Q9BUB7,Q9UP83,P42892,O75844,Q9Y619,P16435,Q86XL3,Q99720,Q7LGA3,Q96AY3 30 +Hypomelanotic macule 0.5179024527770075 0.1467957011538103 0.8832932779082245 1.0 1.0 2 P49815 1 +Short 1st metacarpal 0.3581710414902495 0.1464446423177285 0.8835703876863319 1.0 1.0 6 Q9UQE7,Q14683,Q6KC79,O60885,O60216 5 +Aplasia hypoplasia of the gallbladder 0.5115623237450747 0.1433837312062772 0.8859871308288914 1.0 1.0 3 P18583,A5YKK6 2 +Abnormal coronary artery morphology 0.3166619690950408 0.1404086521311258 0.8883371221615228 1.0 1.0 8 P22413,P16278 2 +Craniofacial dysostosis 0.4032947897166535 0.1403130766005131 0.888412632901102 1.0 1.0 4 Q6NUK1 1 +Abnormal blood transition element cation concentration 0.2886671162683952 0.1402862897793163 0.8884337963728957 1.0 1.0 13 Q15904,Q6PGP7,O43819,Q9Y487 4 +Pain in head and neck region 0.3322228645448852 0.1399698607823606 0.8886838035392148 1.0 1.0 7 Q15043 1 +Curly hair 0.3053110258467762 0.1398964202266147 0.8887418297210046 1.0 1.0 11 P55795,Q96A33 2 +Hypergranulosis 0.5088087154058194 0.1382320355468686 0.8900570374182593 1.0 1.0 3 P16615 1 +Right bundle branch block 0.2948895251374659 0.1380244992585101 0.8902210552487637 1.0 1.0 12 Q9HD47,P36543 2 +Cyanosis 0.2729649904024521 0.1368216728264577 0.8911717523081242 1.0 1.0 20 P51812,O75844,Q99758,P22413,P98175 5 +Muscular dystrophy 0.2563932209179112 0.1352706088950521 0.8923979221675431 1.0 1.0 28 Q8WXH0,P50402,Q9BTV4,O14979,P02545,O43505,Q5JTV8,Q9H9S5 8 +Juvenile aseptic necrosis 0.3304679375054985 0.1342157469817088 0.8932319742833221 1.0 1.0 7 Q9Y619,Q9H173 2 +Absent thumbnail 0.375010465561046 0.1340453146325038 0.8933667418526146 1.0 1.0 5 P21281,Q9H936,O14936 3 +Persistent head lag 0.3298706708017362 0.1322734962785618 0.8947679700601241 1.0 1.0 7 Q01082,Q5XKP0 2 +Eeg with generalized slow activity 0.311498630044843 0.1318334131425391 0.8951160573344226 1.0 1.0 9 Q9H3H5,O75503,P20700 3 +Areflexia 0.2953545460947445 0.1314186009458642 0.8954441748479327 1.0 1.0 105 Q8TD16,O14653,Q969X5,Q7LG56,P02545,O75787,O95721,Q9H9S5,P05023,P07196,Q8TB36,Q13510,Q9NR77,P51114,P10253,Q96RL7,O60313,Q96RR1,O43505,Q9BT22,Q9BQT8,Q9NWS8,P12235,Q13586,O00429,Q15067,Q13217,O15269,Q9H6K4 29 +Pruritus 0.2591561424785643 0.1305620596042336 0.8961217577898131 1.0 1.0 24 P22830,P16615,Q5JRA6,Q96A33,P22413,Q14739 6 +Focal impaired awareness seizure 0.2658825580545578 0.1285311516218646 0.8977286472402459 1.0 1.0 22 Q9NP80,P42345,O00429,Q01105 4 +Broad hallux phalanx 0.5074711023400222 0.128423105376425 0.8978141471050405 1.0 1.0 2 P98172 1 +Abnormality of the antihelix 0.3020325285702504 0.1272206079366579 0.8987657951325787 1.0 1.0 11 P98175 1 +Impaired mastication 0.3504865431707341 0.1241401360178859 0.9012043199803466 1.0 1.0 6 P01889 1 +Abnormality on pulmonary function testing 0.2650936319522559 0.1237898297910738 0.9014816845258016 1.0 1.0 22 Q9BQT8,Q969G3,Q9H9S5,P16278 4 +Nonprogressive 0.3264039430982365 0.1211628595935127 0.9035620410868356 1.0 1.0 7 Q9NQZ5 1 +Broad philtrum 0.3110457874579218 0.1209434053631869 0.903735861977982 1.0 1.0 8 Q9UM00,Q01082,Q969G3 3 +Hoarse voice 0.2540164689716835 0.1189895869165876 0.90528360560538 1.0 1.0 30 Q9Y4P3,Q96HY6,Q15022,Q13045,Q13510 5 +Elfin facies 0.3255223037831855 0.1183818961364763 0.9057650696943188 1.0 1.0 7 Q9Y4P3,Q9UIG0,P35250,Q9Y285,Q15056,O43709 6 +Non motor seizure 0.2618870120371358 0.1176220985968584 0.9063670943438265 1.0 1.0 48 P51812,Q01105,Q13510,O43292,P00374,Q9NVI7 6 +Lipodystrophy 0.2503338562607468 0.1174787066293126 0.9064807168392984 1.0 1.0 39 Q8WXH0,P42166,Q6NUK1,O75844,Q03252,P36543,P50402,Q9BTV4,P42167,P28070,P02545,P04066,Q9Y487,P09493 14 +Abnormality of pelvic girdle bone morphology 0.2468077952889298 0.1160747237574325 0.9075933209037363 1.0 1.0 166 Q9H267,P36543,Q8TD16,Q969X5,Q9BXW9,Q9UHX1,P02545,Q8IZA0,Q9NVI7,Q9H9S5,P16278,P55011,Q9Y4P3,Q96A33,Q9Y584,P22413,O95202,P51812,P30153,O00754,Q15643,Q15125,Q9Y487,Q7RTS9,Q9H173,O75844,Q8WTW3,Q9Y619,Q9Y366,P16435,P08236,Q96HY6,Q04656,Q8TAA9,Q03252,Q5H8A4,P01889,Q14739,Q7LGA3,Q96AY3,O96028,Q12768,P62258 43 +Broad ribs 0.3475719937711475 0.1159892302197045 0.907661077222966 1.0 1.0 6 P16278 1 +Abnormality of tibia morphology 0.2727483255414035 0.1147306078043387 0.9086586525956192 1.0 1.0 16 P16435,Q32P28,P22413,Q7RTS9 4 +Abnormality of hair texture 0.2723116457410681 0.1142942937404452 0.9090045057940052 1.0 1.0 58 P51812,Q6NUK1,O75844,P33897,P36543,P55795,Q96A33,P54802,Q15125,Q9Y487,P42345,Q9NVI7,P15586 13 +Adducted thumb 0.2530003936835753 0.1130396262367852 0.9099991393390228 1.0 1.0 31 Q9Y4P3,P33897,Q8NCH0,P42892,Q96AA3 5 +Ureterocele 0.3665349887133217 0.1130262611288838 0.910009735246581 1.0 1.0 5 Q15149,Q9H936,P09471,O14936 4 +Overlapping toe 0.2563665369006215 0.1126271266686816 0.9103261779085896 1.0 1.0 24 Q96A33,Q9UHX1 2 +Impairment of activities of daily living 0.2749460847724315 0.1126067154030365 0.9103423607959448 1.0 1.0 61 P51812,P07196,P33897,P35637,P21964,Q8TAA9,Q9NZJ7,Q99720,Q969G3,Q9UBB4,P20700,Q06787,Q9UP83,O15269,P07602,Q12768 16 +Narrow nose 0.3463166807789974 0.1125316338489582 0.9104018888470172 1.0 1.0 6 Q14683,O75431,Q9Y4A5,Q9Y4L1,Q07864 5 +Impaired tandem gait 0.268511049928524 0.1119252157456496 0.9108827029476274 1.0 1.0 20 Q5HYK3,Q7LGA3,Q06787 3 +Biparietal narrowing 0.2884056612973966 0.1119098707289293 0.910894870060635 1.0 1.0 12 Q9UGJ1,O75845 2 +Lymphocytosis 0.3659939614869666 0.111728589206272 0.9110386103424504 1.0 1.0 5 Q03252 1 +Neoplasm of the thyroid gland 0.2525447716599684 0.1110421978881263 0.9115828845482954 1.0 1.0 26 P33897,Q04656,Q969G3,P49327,P02545,P21912,P42892,P10644 8 +Foot dorsiflexor weakness 0.2480406025742432 0.1098317536514782 0.9125428076061486 1.0 1.0 38 P07196,Q99720,Q7LG56,O15269,P02545,Q9NR77,Q14739,Q9BQT8,P05023 9 +Juvenile cataract 0.3226990400903509 0.1095994828041307 0.9127270208504328 1.0 1.0 7 Q8WVX9,Q8TC12,Q8NC56,Q9H2P0,Q01082,Q9H1A4 6 +Spastic paraparetic gait 0.3450480982703178 0.1090701259486813 0.9131468695366672 1.0 1.0 6 Q15043 1 +Oculogyric crisis 0.3060156904363994 0.1089329572905975 0.9132556660435572 1.0 1.0 10 Q01105 1 +Impairment in personality functioning 0.2218599445848737 0.1083707384396366 0.9137016117503364 1.0 1.0 222 P35637,Q13045,Q9NZJ7,Q7LG56,P50897,O76024,P05067,P06280,Q9H2C2,P17900,Q92804,P04062,P00403,P21912,Q06787,O75503,P07602,Q15165,P51812,Q96CU9,P16615,P21964,Q6DKK2,P55795,P03886,Q96RL7,P12235,Q96N66,Q8TAA9,Q5HYK3,Q9P0J0,Q7KZN9,Q7LGA3 33 +Overriding aorta 0.3046364379964061 0.107809649931907 0.9141466879711466 1.0 1.0 9 P53701,Q9Y4P3,P35250 3 +Glomerulonephritis 0.2652335978863303 0.1076859995820512 0.914244775641404 1.0 1.0 21 Q03252,O43707,Q96D53,Q8N1F7,Q8NFH4 5 +Abnormal midbrain morphology 0.3070291745509083 0.1075253817789531 0.9143721903008726 1.0 1.0 8 P04062 1 +Abnormal natural killer cell morphology 0.3881523272214339 0.1073346282679666 0.9145235138295928 1.0 1.0 4 Q13546,P33991,O95394 3 +Reduced natural killer cell count 0.3881523272214339 0.1073346282679666 0.9145235138295928 1.0 1.0 4 Q13546,P33991,O95394 3 +Abnormal systemic arterial morphology 0.2584826129054516 0.1054534413493005 0.9160160123480074 1.0 1.0 157 Q9NZJ7,Q9UHX1,P00846,P05067,P16278,P38435,P17900,P04062,Q13510,P06865,Q6ZXV5,O15118,P07602,P21964,P10253,Q96PU5,P03886,Q9NWM8,P10619,O75844,Q7LGA3 21 +Profound global developmental delay 0.2687534989986943 0.105288713306046 0.9161467186720832 1.0 1.0 17 Q9H490,O75381,P40855,O60313 4 +Abnormal shape of the palpebral fissure 0.2733614084382834 0.1046959463845251 0.916617078602131 1.0 1.0 14 Q9UHX1 1 +Ventilator dependence with inability to wean 0.4916831124894475 0.1034510543311915 0.9176049939736612 1.0 1.0 2 O75648 1 +Calcification of the aorta 0.3204130520235288 0.102626881224345 0.9182591073494336 1.0 1.0 7 P04062 1 +Allergy 0.30499858796949 0.1009045379774495 0.9196262407122244 1.0 1.0 8 Q6P1M0,P00813,Q9Y5S9,P16885,Q01082,P42345,O95394 7 +Abnormality of temperature regulation 0.2893653521470527 0.1008897670014719 0.91963796640857 1.0 1.0 119 P23786,P10253,Q13586,P03886,Q9NZJ7,Q13510,P00403,Q96D53,Q9NR77,P00846,Q9NZ08,Q14739,P51797,Q5XKP0,P07602,Q9HC07 16 +Tube feeding 0.2816487859823394 0.1006966296431331 0.9197912869310692 1.0 1.0 71 Q96N66,P33897,P30153,Q01105,P35637,Q9NZJ7,Q99720,O00429,Q9UHX1,Q9UP83,P51797,Q9H490,P07602 13 +Hip contracture 0.2792277069280253 0.1004945234451125 0.9199517304867456 1.0 1.0 13 Q7LGA3,Q96AY3 2 +Decreased specific antibody response to vaccination 0.3847672778561227 0.1004724709901041 0.9199692371946212 1.0 1.0 4 Q13546,P17812,P50851 3 +Lambdoidal craniosynostosis 0.4846196942795301 0.0970863789109658 0.922657797813007 1.0 1.0 3 P16435 1 +Abnormality of cardiovascular system electrophysiology 0.2846516757234648 0.0967906154699833 0.922892676711689 1.0 1.0 128 Q8WXH0,P23786,O75880,O75381,P36543,P13473,Q9NZJ7,Q7LG56,P02545,P00846,P06280,Q9H490,Q9Y4P3,Q8TB36,P04062,P00403,Q07954,P21912,Q9HD47,P22413,P07602,Q16836,O75208,P50402,P10253,Q9BTV4,P03886,P50416,Q96RR1,Q9BUB7,P53701,P42892,P12235,P01889,Q99758,O15460,P40855,P09493 38 +Abnormal circulating fatty acid anion concentration 0.2783090258364497 0.0967890719071043 0.922893902541256 1.0 1.0 13 P23786,Q16836 2 +Abnormal skin morphology of the palm 0.2917471892939452 0.0955977513060078 0.923840051219778 1.0 1.0 97 O75381,Q06136,Q9UHX1,O95721,P21912,O95202,Q9UID3,P51812,P16615,Q8NCH0,Q96I36,P42167,P98175,Q9Y487,P42345,Q6NUK1,Q14739,P40855,O96028 19 +Mild short stature 0.4832963411705097 0.0950479300441039 0.9242767565473138 1.0 1.0 3 Q14739 1 +Abnormal male reproductive system physiology 0.2501060855346703 0.0927606614423546 0.926093703834812 1.0 1.0 41 Q9Y4P3,P33897,P16435,P04062,Q969G3,Q13423,Q06787,O76024 8 +Poikiloderma 0.3384137736381564 0.0915067158691163 0.927089970135317 1.0 1.0 6 Q92889,P19447,P18074,O75431,Q9H1A4 5 +Horizontal eyebrow 0.338320387676723 0.0912659992055958 0.927281233907896 1.0 1.0 6 P11233,Q16531 2 +Abnormality of peripheral nerves 0.268591186353345 0.0904453273674236 0.9279333382372 1.0 1.0 57 P07196,Q9Y619,Q9NZJ7,Q7LG56,Q96RL7,Q99720,Q9NR77,O15269,P07602 9 +Progressive 0.287087070299065 0.0890241243481444 0.9290627377794828 1.0 1.0 122 Q96D71,P33897,O14653,Q7LG56,Q8N1F7,P02545,O00400,Q5XKP0,O95470,P04062,Q13126,Q13510,P54802,Q15043,P27544,Q96RL7,Q96D53,O75569,O60313,Q96RR1,Q9NP80,P12235,Q9NR28,Q03252,Q13586,Q99720,O00429,P20700,P15586,Q12768 30 +Occipital meningocele 0.3368028055810537 0.0873796985210021 0.9303697058817062 1.0 1.0 6 P21964 1 +Impacted tooth 0.4780445086504492 0.0871740299639589 0.930533181841846 1.0 1.0 3 O75844 1 +Abnormality of neuronal migration 0.2520205233796846 0.0865521795212848 0.931027478396357 1.0 1.0 161 P23786,Q9H267,Q9UEY8,O75381,P36543,Q8TD16,Q5KU26,Q9NZ01,O95721,Q15392,Q9H9S5,P37268,Q9UGJ1,Q01105,Q9UPT5,Q15058,Q16134,Q6ZXV5,Q06787,Q15051,P51812,Q9C0B1,Q15022,Q96PU5,Q9HC21,O43505,Q9Y487,Q9NWS8,P42345,Q6NUK1,Q96N66,Q03252,Q16625,Q10713,Q86XL3,Q9BSJ2,Q969G3,P20700,Q9Y320,P40855,Q12768,P62258 42 +Aplasia hypoplasia involving bones of the feet 0.2838447547047531 0.0860670781968846 0.9314130942773412 1.0 1.0 77 Q8WTW3,Q9NX62,Q5JRA6,Q03164,Q96A33,Q15643,Q13510,Q9UHX1,P02545,Q9H173,Q5H8A4,P13073,Q7LGA3,Q7RTS9,Q06787,O96028,O95202,Q8N0X7 18 +Chromosome breakage 0.2754960914923879 0.0856325026511136 0.9317585599712256 1.0 1.0 13 P13073,Q06787 2 +Vestibular dysfunction 0.2488372472961628 0.0845727248811994 0.932601083751408 1.0 1.0 32 Q02978,P49327,Q15043,P01889,P21912,Q96RR1,Q9NZ08,O15460,P06280,O60220,P10644 11 +Abnormality of the curvature of the vertebral column 0.247817126097311 0.0839336725861992 0.9331091671576166 1.0 1.0 346 P36543,Q9UHX1,O75787,O75027,Q9H490,Q9HC07,Q9Y4P3,P51648,Q13510,P22413,Q6ZXV5,Q96CU9,Q15022,Q9UG56,Q8N0X7,O75844,Q8WTW3,Q5JRA6,P20700,P01889,Q14108,Q7LGA3,Q12768,Q8WXH0,Q13045,Q969X5,P16278,Q01105,Q96A33,P04062,Q9NR77,P51812,P21964,Q96PU5,Q8NCH0,Q9NWM8,Q96HY6,Q99720,Q14739,P35637,Q5KU26,Q32P28,Q9NVI7,P07196,O95202,P30153,P50402,P51571,P55795,Q15125,Q9BT22,P98175,Q9BQT8,Q7RTS9,P16435,Q8TAA9,Q5H8A4,Q96AY3,O96028,Q8TD16,O14653,Q7LG56,Q9H9S5,Q9UGJ1,P07237,Q15043,P21912,Q06787,O00754,Q15643,Q9Y487,Q6NUK1,P08236,Q03252,Q10713,Q969G3,O00429 77 +Increased urine proteinogenic amino acid derivative level 0.4767409078094374 0.0828974102554698 0.9339331132718338 1.0 1.0 2 P48637 1 +Abnormal cerebral cortex morphology 0.2278257171133522 0.0821208629662536 0.9345506029079812 1.0 1.0 251 P23786,O75381,P36543,P35637,Q8TD16,Q5KU26,P00846,O76024,P05067,O95721,Q15392,Q9H9S5,P37268,Q9UGJ1,Q9Y4P3,Q01105,Q9UPT5,P04062,P00403,Q16134,Q6ZXV5,Q06787,O75503,P51812,Q15022,O00754,Q96PU5,P03886,Q9HC21,Q96RL7,O43505,Q9BUB7,Q9Y487,Q9NWS8,P42345,Q8WTW3,Q9Y619,Q96N66,Q03252,Q16625,Q10713,Q86XL3,Q9BSJ2,Q969G3,Q9Y320,Q7LGA3,P40855,Q96AA3 48 +Decreased circulating total igm 0.289552015917073 0.0819149099878785 0.934714377830442 1.0 1.0 11 Q15904 1 +Decreased circulating androgen concentration 0.2965260945710814 0.0810885770903801 0.9353715099332052 1.0 1.0 9 P16435 1 +Atresia of the external auditory canal 0.2666939745809333 0.0805546682476862 0.935796118483361 1.0 1.0 15 Q9Y619 1 +Increased hepatocellular lipid droplets 0.4730758387369692 0.0783012008909029 0.9375884622248544 1.0 1.0 2 Q9Y6B6 1 +Abnormality of the biliary system 0.2830091850514044 0.0771806325574229 0.9384798486631664 1.0 1.0 128 P09601,Q9NZJ7,Q9UJW0,Q5XKP0,P00374,Q96A33,P04062,Q13510,Q16134,O15118,O95202,P07602,P22830,P21964,Q16625,Q5H8A4,Q15904,Q14108,Q14739,P40855,O96028 21 +Developmental cataract 0.2715935972080273 0.0752825752365101 0.9399898850832936 1.0 1.0 62 Q53H12,P03886,P00403,Q16134,O76024,O00400,Q15800,Q9NVI7 8 +Generalized limb muscle atrophy 0.2946327683615931 0.0751176408041499 0.9401211121469876 1.0 1.0 9 Q8IY17,Q6PI48,O43819,Q9Y606,P49589,Q9Y2Z4,Q9Y2U8,P06753 8 +Hemoglobinuria 0.3709449929478022 0.0744012643962491 0.9406911027509396 1.0 1.0 4 Q969N2,O14936,P37287 3 +Apnea 0.2886648048183386 0.0740607097303255 0.9409620784597736 1.0 1.0 92 P51812,P23786,P51114,Q96CU9,Q86Y39,Q96A33,P03886,P04062,Q9NZJ7,O60313,Q9P0J0,P00846,Q7KZN9,O76024,P07602,Q9UID3 16 +Adrenocorticotropin deficient adrenal insufficiency 0.4691288412743307 0.0735430122955289 0.9413740178583928 1.0 1.0 2 O00170 1 +Abnormal serum insulin like growth factor 1 level 0.4691288412743307 0.0735430122955289 0.9413740178583928 1.0 1.0 2 O00170 1 +Abnormal platelet volume 0.2930381503528647 0.0701682083883167 0.9440597779659304 1.0 1.0 9 Q6PGP7,Q14739,O75845 3 +Decreased circulating igg level 0.2650438967369005 0.07000608187271 0.9441888188820492 1.0 1.0 14 Q15904 1 +Abnormal circulating aromatic amino acid concentration 0.3465011286681787 0.0685636797740585 0.9453369301443776 1.0 1.0 5 Q9UJS0,P09417,P16930,P61457 4 +Mesoaxial polydactyly 0.4646179870313067 0.0683447471284779 0.9455112043204787 1.0 1.0 2 Q2M1P5 1 +Short fourth metatarsal 0.4646179870313028 0.0683447471284738 0.945511204320482 1.0 1.0 2 Q96S52 1 +Diffuse mesangial sclerosis 0.2602489104134676 0.0682050816030163 0.9456223818595764 1.0 1.0 20 Q96D53,O43707,Q8N1F7,O95470 4 +Cutaneous melanoma 0.4639029892837038 0.0676687988736048 0.9460492872513516 1.0 1.0 3 P19447,P11802 2 +Inferior lens subluxation 0.4639029892837026 0.0676687988736031 0.9460492872513528 1.0 1.0 3 O75533,P29992 2 +Mydriasis 0.4639029892837026 0.0676687988736031 0.9460492872513528 1.0 1.0 3 O75533,P29992 2 +Lens subluxation 0.4639029892837026 0.0676687988736031 0.9460492872513528 1.0 1.0 3 O75533,P29992 2 +Choroidal melanoma 0.4639029892837026 0.0676687988736031 0.9460492872513528 1.0 1.0 3 O75533,P29992 2 +Uveal melanoma 0.4639029892837026 0.0676687988736031 0.9460492872513528 1.0 1.0 3 O75533,P29992 2 +Abnormal ciliary body morphology 0.4639029892837026 0.0676687988736031 0.9460492872513528 1.0 1.0 3 O75533,P29992 2 +Photopsia 0.4639029892837026 0.0676687988736031 0.9460492872513528 1.0 1.0 3 O75533,P29992 2 +Ectropion of lower eyelids 0.463772201860733 0.0673981840214332 0.9462647148444944 1.0 1.0 2 O60716 1 +Hypogonadotropic hypogonadism 0.2465364490136204 0.0662109133044774 0.947209908281538 1.0 1.0 30 P03886,Q7LG56,P00403,Q969G3 4 +Focal onset seizure 0.2872529051922338 0.0656063019957053 0.9476912716586364 1.0 1.0 90 Q96N66,Q01105,Q9UPT5,Q96PU5,P03886,Q9NZJ7,P00403,Q969G3,P21912,Q9UBX3,Q6ZXV5,Q9NP80,O75503,P42345,P07602 15 +Insulin resistance 0.2595704096655598 0.0647624269019063 0.9483631576078182 1.0 1.0 20 O75844,Q03252,P22413,O76024 4 +Abnormality of hair pigmentation 0.2451287080893951 0.062904354582883 0.9498426672586686 1.0 1.0 26 Q6PGP7,Q04656,P49327,Q13126,P02545,P10644,Q9UM00,Q86YV9,P37268 9 +Abnormality of the thoracic cavity 0.2631160433073355 0.0623564541200726 0.950278972016212 1.0 1.0 14 P01889,Q969G3,Q01844 3 +Dry hair 0.4591088550479494 0.0616091352812049 0.9508741018623956 1.0 1.0 3 O60828,Q9Y276 2 +Semilobar holoprosencephaly 0.3633286318758759 0.0613718368776308 0.9510630809839592 1.0 1.0 4 Q8N3U4,Q14683,A5YKK6 3 +Periauricular skin pits 0.2830414248203223 0.0602003597419989 0.95199605920356 1.0 1.0 11 P61978,Q8N3U4,Q07954,O96028,O95202 5 +Overfriendliness 0.3254304261924872 0.0597986536983568 0.9523159978529214 1.0 1.0 6 Q9Y4P3,Q9UIG0,P35250,Q15056,O43709 5 +Phonophobia 0.3254304261924872 0.0597986536983568 0.9523159978529214 1.0 1.0 6 Q9Y4P3,Q9UIG0,P35250,Q15056,O43709 5 +Nystagmus induced head nodding 0.3254304261924872 0.0597986536983568 0.9523159978529214 1.0 1.0 6 Q9Y4P3,Q9UIG0,P35250,Q15056,O43709 5 +Flat cornea 0.3254304261924872 0.0597986536983568 0.9523159978529214 1.0 1.0 6 Q9Y4P3,Q9UIG0,P35250,Q15056,O43709 5 +Abnormal 3rd finger morphology 0.4574168076706157 0.0595361519977276 0.9525250714032722 1.0 1.0 3 Q9Y3E5,Q71SY5 2 +Fibroadenoma of the breast 0.4572839288168093 0.0593748007980424 0.9526535836908844 1.0 1.0 3 P49327 1 +Small earlobe 0.2912956484431046 0.059152373327776 0.9528307437532456 1.0 1.0 8 P98175,P21964 2 +Decreased circulating acth level 0.3416442313725744 0.0589048161836359 0.953027921955157 1.0 1.0 5 Q969G3,P10644 2 +Scleroderma 0.3416341875034346 0.0588852966560811 0.9530434692974604 1.0 1.0 5 Q14739 1 +Cervical spinal canal stenosis 0.4555962785452724 0.0586968836871746 0.9531935415177156 1.0 1.0 2 Q9NSE4 1 +Loss of eyelashes 0.4566212468990888 0.0585732537362586 0.9532920145225554 1.0 1.0 3 O75844 1 +Coarse facial features 0.2760536487558675 0.0572049102839932 0.9543819667268196 1.0 1.0 70 P51812,Q9Y4P3,P08236,O00754,Q96A33,Q969G3,P54802,Q06787,Q7LGA3,P06280,Q7RTS9,P15586,P16278,P10619 14 +Abnormality of prenatal development or birth 0.2308195853135422 0.0568067824753846 0.9546991110309592 1.0 1.0 269 P23786,O75381,Q8TD16,Q86Y39,Q13045,Q9UHX1,O43676,Q9NVI7,Q86WC4,P16278,Q9H2C2,P04062,Q13510,Q9NPL8,O15118,O95202,P51114,Q96CU9,P21964,Q9HC21,P03886,Q15643,Q96I36,O60313,Q15125,Q9BT22,Q9BUB7,Q96J42,Q9UP83,Q9Y487,O96000,P10619,O75844,Q9Y619,Q6NUK1,P16435,P08236,Q8TAA9,O00429,Q5H8A4,Q70HW3,Q14739,Q7KZN9,Q7LGA3,P40855,O96028 46 +Inappropriate antidiuretic hormone secretion 0.452213137863006 0.0553297074860916 0.9558757952583616 1.0 1.0 2 Q13724 1 +Hypopigmentation of the skin 0.2644419171413014 0.0552581927093643 0.955932768632171 1.0 1.0 57 Q6PGP7,O75312,Q04656,P21964,Q9NZJ7,P49327,Q9BXW9,P02545,Q15125,Q9NP58,Q01082,Q8IZA0,P21912,P53701,Q86YV9,P42345,P07602,P51798 18 +Abnormal sperm motility 0.45346869712354 0.0548311987465172 0.9562729447765346 1.0 1.0 3 Q86Y56,Q9UBS4 2 +Prominent supraorbital ridges 0.2672887177755888 0.0547437046271563 0.9563426502886732 1.0 1.0 13 P51812,Q15022 2 +Oral ulcer 0.2877625759364568 0.0543160306115516 0.9566833778256564 1.0 1.0 9 P01889,Q9NZ08 2 +Holoprosencephaly 0.2601170312843845 0.053325750902711 0.9574723631338496 1.0 1.0 15 Q96J42 1 +Aphthous ulcer 0.3025243458039278 0.0524537115598097 0.9581671773499184 1.0 1.0 7 P01889,Q9NZ08 2 +Nocturnal hypoventilation 0.451349735261939 0.0523816312391749 0.958224610169096 1.0 1.0 3 Q9H9S5 1 +Abnormality of bone mineral density 0.2572300502031414 0.0510897435615274 0.9592540087730914 1.0 1.0 155 Q9NZJ7,Q32P28,Q7LG56,P06280,Q9H490,Q15392,Q9HC07,P16278,Q86WC4,Q9Y4P3,P07237,P04062,Q13126,Q13510,P54802,Q15043,O43292,P07602,O95202,O75845,O00754,Q9HC21,Q15643,Q15125,Q9Y487,Q9NWM8,P12235,O75844,Q96HY6,Q5H8A4,Q14108,Q14739,Q96AY3,O96028 34 +Food allergy 0.3562764456981602 0.0501469085562777 0.9600053191132838 1.0 1.0 4 Q01082,Q9Y5S9,O95394 3 +Deposits immunoreactive to beta amyloid protein 0.4490420465003124 0.0497734000124397 0.9603029641166244 1.0 1.0 3 P05067 1 +Abnormality of circulating enzyme level 0.287180443018919 0.0494339952050536 0.9605734370133248 1.0 1.0 109 Q8WXH0,P23786,O14653,P13473,Q969X5,Q7LG56,P53985,P02545,Q5JTV8,Q9BPX6,Q9HC07,Q9H9S5,P07196,Q9Y4P3,Q9Y584,Q6ZXV5,Q07021,P15291,Q16836,P50402,P10253,O14979,Q9BTV4,Q96RL7,P42167,P50416,Q96RR1,O43505,Q9NWM8,P12235,Q13586,P09493,P46020 33 +Edema of the dorsum of hands 0.4457287848886455 0.0492461743417777 0.9607231140789668 1.0 1.0 2 Q9Y263 1 +Edema of the dorsum of feet 0.4457287848886455 0.0492461743417777 0.9607231140789668 1.0 1.0 2 Q9Y263 1 +Crumpled long bones 0.4484661278926072 0.0491320942814274 0.9608140267463868 1.0 1.0 3 P07237 1 +Abnormal enzyme coenzyme activity 0.2149427373254425 0.0484346623283517 0.961369835167627 1.0 1.0 207 P23786,O75880,Q9NZJ7,Q7LG56,O75787,P00846,O14678,Q5XKP0,Q9HC07,P16278,Q9H9S5,Q8N511,Q96A33,P04062,Q13510,P22413,Q07021,O15118,P07602,Q16836,O75845,P10253,O00754,P03886,Q9NW15,Q96RL7,P50416,O43505,Q9UP83,P10619,P12235,Q9Y619,Q16625,Q10713,Q15067,Q15904,Q14739,P40855,Q96AY3 39 +Synostosis of joints 0.2415972016486857 0.0460320740799331 0.963284685578084 1.0 1.0 39 Q9Y4P3,P16435,Q8TAA9,Q9UHX1,O96028,O95202,Q9H9S5 7 +Fasting hypoglycemia 0.4452904681331173 0.045664369957477 0.9635777628238548 1.0 1.0 3 Q9NSE4,O43772 2 +Partial agenesis of the corpus callosum 0.2566619951915365 0.0436060704081893 0.9652184128162656 1.0 1.0 16 Q9HC21,Q15392,Q86WC4 3 +Cystic hygroma 0.2840196053814664 0.0435597995952347 0.9652552965370932 1.0 1.0 9 Q14739 1 +Acute hepatic failure 0.2574147610901038 0.0426648247095517 0.9659687198389588 1.0 1.0 15 P01889,Q16836,Q9P2J5 3 +Dialeptic seizure 0.2629167781656565 0.042635447028787 0.9659921385274868 1.0 1.0 57 P51812,Q01105,P42345,O14653,Q13510,O43292,Q9NP80,P00374,Q9NVI7 9 +Low set posteriorly rotated ears 0.2789231289931956 0.0417178736897117 0.9667236052207592 1.0 1.0 77 Q6NUK1,Q9Y4P3,P16435,O75381,Q10713,Q15022,P04062,Q8NCH0,Q5H8A4,P98175,P40855,Q96J42,O95202,O96028,Q15392,P37268 16 +Cessation of head growth 0.2981366459627361 0.0413606530552699 0.9670083802511132 1.0 1.0 7 Q9NR50,Q14232,Q05086,Q9Y263,Q9UI10,P49770 6 +Severe failure to thrive 0.4404935173536488 0.0406436614484121 0.967579976093356 1.0 1.0 3 O75844 1 +Noncompaction cardiomyopathy 0.3495639550469889 0.0402030641880994 0.9679312347379944 1.0 1.0 4 P21912,Q15233 2 +Minimal change glomerulonephritis 0.2557999766830544 0.040110493580597 0.9680050358678538 1.0 1.0 16 Q96D53,O43707,Q8N1F7 3 +Protruding ear 0.2525345209067537 0.0398494118635682 0.9682131825214432 1.0 1.0 48 P51812,Q9Y4P3,P61978,Q06136,Q8NCH0,Q9BSJ2,P20700,Q01082,Q8N6M0,O43505,Q06787,Q9H9S5,Q9UGJ1 13 +Hepatitis 0.2549629496357888 0.0395699773699135 0.9684359632726904 1.0 1.0 19 Q9Y619,P08236,Q04656,P49327,P11717 5 +Anisopoikilocytosis 0.4392816032800356 0.0394160991134181 0.9685586446472813 1.0 1.0 3 O75845 1 +Narrow jaw 0.4336058641105237 0.0391236671222517 0.968791791777103 1.0 1.0 2 P53007 1 +Tracheobronchomalacia 0.4327600789399741 0.038475824948886 0.96930830610411 1.0 1.0 2 Q9H9B1 1 +Hypophosphatemia 0.3152106849865042 0.0373575114432284 0.9701999499610852 1.0 1.0 6 P53680,P22413,P51798 3 +Bilateral single transverse palmar creases 0.2559553664417394 0.0370368205675442 0.9704556473021372 1.0 1.0 15 P40855 1 +Abnormal reflex 0.2543235043080374 0.0368123488923122 0.9706346277309764 1.0 1.0 400 O14949,O75787,O75027,P00846,Q9Y4P3,P17900,O15020,Q13510,O14773,P07602,Q53FT3,Q96CU9,P49902,P10253,O14979,P03886,P50416,P13073,Q8N0X7,Q86XL3,Q9BSJ2,Q15067,P20700,P01889,Q9P0J0,Q7KZN9,Q9H6K4,Q12768,Q8WXH0,P33897,Q96IX5,Q13045,Q969X5,P02545,Q9NZ08,O00400,Q5XKP0,P05023,Q9H2C2,Q8TB36,Q9HD42,P04062,P54802,P49327,Q15058,Q9UBB4,Q9NR77,O75503,P51812,O75746,Q6DKK2,Q9BTV4,O43681,Q96RL7,O60313,O75569,Q96RR1,O43505,Q14203,O60220,P12235,Q9H173,Q9Y619,Q04656,Q13586,Q99720,Q14739,P40855,P35637,Q5KU26,Q9NZJ7,Q86WC4,P07196,Q9BRK0,O43292,P51114,O75208,P50402,Q9NW15,Q9BT22,Q9BQT8,Q7RTS9,Q96N66,Q16625,Q8TAA9,Q5H8A4,Q5HYK3,Q96AY3,O15269,Q96AA3,O75381,Q8TD16,O14653,Q7LG56,O95721,Q9H9S5,Q15043,P21912,Q06787,O00754,Q9HC21,Q9UP83,Q9NWS8,Q10713,O00429,Q9Y320,Q13217 107 +Abnormal vitreous humor morphology 0.2828852122056218 0.0363989438589191 0.9709642563013854 1.0 1.0 10 P53701,P04439,Q9NX14 3 +Impaired tactile sensation 0.2828232013466079 0.036225670366723 0.9711024174268984 1.0 1.0 10 Q9NR77 1 +Skin ulcer 0.2418011225473647 0.0346610324201111 0.97235003386708 1.0 1.0 30 P04062,P01889,Q03518,Q8IZA0,O15460,Q14739,O15269 7 +Blue sclerae 0.2429620472497095 0.0325888058595822 0.9740024967202934 1.0 1.0 24 P07237,Q8NCH0,Q96AY3 3 +Abdominal aortic aneurysm 0.3437100382689167 0.0321112762869716 0.9743833108720514 1.0 1.0 4 P01889 1 +Horizontal ribs 0.4223287285029676 0.0310783897048399 0.975207023860841 1.0 1.0 2 Q8NCM8 1 +Decreased fertility in females 0.2930533980314227 0.0291150737158361 0.976772813807816 1.0 1.0 7 O00170,Q96RD7,P51809 3 +Rectal prolapse 0.2800172451784632 0.028505796462654 0.9772587450005628 1.0 1.0 10 P51812 1 +Central hypoventilation 0.292296663149931 0.0273478321910561 0.9781823065469852 1.0 1.0 7 Q14203,O43819 2 +Retinal dystrophy 0.2658990208173212 0.0272908326791343 0.9782277686091364 1.0 1.0 62 Q9H2C2,O75381,O75312,Q6P4Q7,P03886,O43505,P00846,P40855,Q9H9S5,Q9Y287,P38435 11 +Epileptic spasm 0.2732777214227754 0.0270214415312687 0.9784426324053032 1.0 1.0 71 P03886,Q13510,P00846,Q9UBX3,P13073 5 +Hypoventilation 0.2528505234503097 0.0241778312165326 0.9807107610873712 1.0 1.0 14 P61978,O43819,Q8N183,Q14203,Q9H9S5 5 +Incomitant strabismus 0.2512257311678184 0.0237123099924469 0.981082086813334 1.0 1.0 18 Q7LGA3,O60313 2 +Abnormal placental membrane morphology 0.4093600225542781 0.0233162970175592 0.9813979721076996 1.0 1.0 2 P21281 1 +Ectodermal dysplasia 0.4093600225542781 0.0233162970175592 0.9813979721076996 1.0 1.0 2 P21281 1 +Short long bone 0.244081078051576 0.023133942075535 0.9815434310643047 1.0 1.0 43 Q8WTW3,Q9Y366,Q04656,Q96HY6,Q15643,Q9BXW9,Q9UHX1,Q9H173,P98175,Q7RTS9,P16278,P10644 12 +Colpocephaly 0.2776051962722291 0.0226634154630408 0.9819187585661072 1.0 1.0 8 O60341,Q9NVI1,Q8N3U4,O94979,P53701,Q86XI2,Q9NX14 7 +Abnormal length of corpus callosum 0.407386523822962 0.0222647093969657 0.98223679972109 1.0 1.0 2 P11177 1 +Nevus 0.2394047417704534 0.0220129629268822 0.9824376151236128 1.0 1.0 34 Q6NUK1,Q9Y4P3,Q15022,Q9UHX1,P35250,Q01082,P21912,Q96AY3,P10644 9 +Annular pancreas 0.3356840620592343 0.0218768727457068 0.9825461732351424 1.0 1.0 4 Q9Y4R8,Q9BXW9,O95155 3 +Abnormality of the nasal skeleton 0.3353647166097383 0.021489866698653 0.9828548868008662 1.0 1.0 4 Q6NUK1 1 +Abnormal renal pelvis morphology 0.2612669412492849 0.0209736540868539 0.9832666720450296 1.0 1.0 58 Q8WTW3,P23786,P16435,O75381,Q5JRA6,Q8NCH0,P20700,Q15125,O43505,P98175,P40855,O76024,Q8N0X7 13 +Corneal scarring 0.4173716864072212 0.0199454197700108 0.9840869126038984 1.0 1.0 3 Q03001,Q86XI2 2 +Upper limb asymmetry 0.4009021708486089 0.0190347964271961 0.9848133468984064 1.0 1.0 2 Q15555 1 +Aplasia hypoplasia affecting the anterior segment of the eye 0.2393590515388549 0.018709133044847 0.985073142414711 1.0 1.0 32 Q13586,P21912,Q7LGA3,Q96J42,O96028,O95202 6 +Flat nasal alae 0.4137055837563516 0.0171675649973735 0.9863029377570895 1.0 1.0 3 P19447,P18074 2 +Abnormality of amino acid metabolism 0.4137055837563516 0.0171675649973735 0.9863029377570895 1.0 1.0 3 P19447,P18074 2 +Xanthomatosis 0.4133078301067094 0.0168740345196764 0.9865371072697252 1.0 1.0 3 P02545 1 +Abnormal circulating estrogen level 0.2682522822464492 0.0159503865886031 0.9872739724194332 1.0 1.0 11 P16435 1 +Abnormal prolactin level 0.3162333797801425 0.0154697602801443 0.9876574094065058 1.0 1.0 5 Q969G3 1 +Ocular albinism 0.3151805869074534 0.0139230517606887 0.9888913708658768 1.0 1.0 5 Q86YV9,O00203,O95155,Q96T58 4 +Recurrent abscess formation 0.3879334648999173 0.0135384226058452 0.9891982316001968 1.0 1.0 2 P53634 1 +Abnormality of dermal melanosomes 0.3879334648999165 0.013538422605845 0.989198231600197 1.0 1.0 2 Q9Y4I1 1 +Simple ear 0.3026613771527496 0.0128461538514094 0.9897505340777824 1.0 1.0 6 Q96KP1,P16435 2 +Viral hepatitis 0.3269393511988683 0.0118247746837226 0.9905654147110114 1.0 1.0 4 Q14790,P35222,P11717 3 +Subacute progressive viral hepatitis 0.3269393511988683 0.0118247746837226 0.9905654147110114 1.0 1.0 4 Q14790,P35222,P11717 3 +Abnormal systemic blood pressure 0.2837049325467257 0.0114449857604332 0.9908684219176438 1.0 1.0 105 O43707,Q9NZJ7,P02545,Q9NP58,P06280,Q9Y4P3,P04062,P00403,P21912,P22413,Q06787,P07602,Q15051,P21964,P03886,O43681,Q13423,Q14203,Q9BUB7,P42892,O75844,P16435,Q10713,Q8TAA9,P20700,P01889,Q99758 27 +Radioulnar synostosis 0.2443442057798821 0.0107691132298209 0.991407656901822 1.0 1.0 22 O96028,P16435,O95202 3 +Absent earlobe 0.3772201860727417 0.0098641297244277 0.992129690818894 1.0 1.0 2 Q02224 1 +Long penis 0.3772201860727368 0.0098641297244261 0.9921296908188956 1.0 1.0 2 O00170 1 +Abnormality of upper limb joint 0.2766240369219117 0.0095380396315238 0.9923898608255768 1.0 1.0 129 Q8WXH0,P23786,Q03164,Q969X5,P02545,Q8IZA0,Q15392,P16278,P37268,P07196,Q9Y4P3,Q8WVM7,Q13510,Q9NR77,P22413,O95202,P50402,Q15022,Q9BTV4,Q15643,Q15125,Q9BUB7,Q9UP83,P42892,Q7RTS9,Q9H173,O75844,Q9Y619,P16435,O96028,Q7LGA3,Q96AY3,Q9H6K4 33 +Abnormality of the foot musculature 0.4019949953328494 0.009146996682135 0.9927018543394104 1.0 1.0 3 O14979 1 +Cystinuria 0.3746828305610373 0.0090970347155352 0.992741716562658 1.0 1.0 2 Q4J6C6 1 +Scrotal hypoplasia 0.2476215081340953 0.007994342007099 0.9936215058798964 1.0 1.0 20 Q6NUK1,P16435 2 +Heinz bodies 0.3707358330983979 0.0079765979436352 0.9936356631427844 1.0 1.0 2 O14936 1 +Aplasia hypoplasia of the sacrum 0.3994336569226174 0.0075585756568678 0.9939691866072508 1.0 1.0 3 Q8TAA9 1 +Abnormal mitochondrial shape 0.3106659142212239 0.007512261147835 0.9940061391898004 1.0 1.0 5 Q00325,Q9GZY8,Q7Z406,P53597 4 +Onychogryposis 0.3681984775866946 0.0073012531419198 0.9941744946015572 1.0 1.0 2 P53634 1 +Delayed ability to roll over 0.3224259520451293 0.0070702412499459 0.9943588106644772 1.0 1.0 4 P82663,P51970,P18583 3 +Tendon xanthomatosis 0.3625599097829181 0.005919450556785 0.9952769893746208 1.0 1.0 2 P34913 1 +Xanthelasma 0.3625599097829181 0.005919450556785 0.9952769893746208 1.0 1.0 2 P34913 1 +Neonatal respiratory distress 0.2380253200216388 0.0058462869438421 0.9953353644816516 1.0 1.0 24 P23786,Q96I36,O96000 3 +Albuminuria 0.3210645521208022 0.0056925729399199 0.9954580084708388 1.0 1.0 4 Q5JRA6 1 +Pneumonia 0.2561654176811682 0.0053229788563852 0.9957528974093272 1.0 1.0 55 Q6NUK1,O00754,P04062,Q969G3,Q13510,O60220,O95721,Q86WC4,P16278 9 +Prominent eyelashes 0.2982136774000212 0.004958066569567 0.9960440514405172 1.0 1.0 6 Q969G3,P20700 2 +Increased serum iron 0.3936648902581983 0.0041880571267274 0.9966584236472692 1.0 1.0 3 Q6PGP7 1 +Sleep wake cycle disturbance 0.2974880045159486 0.0037103430472832 0.9970395813597976 1.0 1.0 6 Q05086,Q14683,Q9Y4R8,Q8N3U4,Q9UBM7 5 +Abnormal hypothalamus morphology 0.3190409026798283 0.0036923664780077 0.9970539244886276 1.0 1.0 4 P35222,Q2M1P5,Q9H269 3 +Death in adulthood 0.2459965319128819 0.0027095223016154 0.9978381166336387 1.0 1.0 16 P51812,P05067,Q9Y4P3,Q9Y276 4 +Lymphedema 0.2459251200429281 0.0024531258345081 0.998042690734064 1.0 1.0 16 P06280,Q14739 2 +Narrow forehead 0.2500973363790489 0.0020945214585234 0.9983288148878944 1.0 1.0 50 O75845,Q96A33,Q9BSJ2,Q9UHX1,P20700,O75787,Q01082,O43292,Q7LGA3,Q9UM00,Q9H490 11 +Torsade de pointes 0.3405694953481836 0.0018820947018407 0.9984983065820024 1.0 1.0 2 Q99996 1 +Anhidrosis 0.2962593077430779 0.0016227111443204 0.9987052643995185 1.0 1.0 6 Q9Y276,P20700 2 +High myopia 0.2690090229328525 0.0005057885869445 0.9995964391126532 1.0 1.0 10 O15460,P36543,Q9Y487 3 +Adrenocorticotropic hormone deficiency 0.3267550042289243 0.0002238112391148 0.9998214244692668 1.0 1.0 2 O00170 1 +Decreased lacrimation 0.2797854319593471 0.0002207006007631 0.9998239063995208 1.0 1.0 7 Q92889,Q9NRG9,Q03001,Q10567,Q7Z392,P55011 6 +Hypoplasia of the uterus 0.267096562004168 7.460451624596643e-05 0.9999404742083764 1.0 1.0 9 Q16740,P53701,Q9NX14,P57740 4 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..30e1bb0573713ec8dc435b49291dc141fe7cc1f1 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal energy expenditure", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal haptoglobin level", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pulse", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of olfactory lobe morphology", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of venous physiology", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Biconvex vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Budd chiari syndrome", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Conjunctival icterus", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to polysaccharide vaccine", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Discoid lupus rash", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalomalacia", "Encephalopathy", "Enchondroma", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypoautofluorescent retinal lesion", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low serum calcitriol", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lupus anticoagulant", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microangiopathic hemolytic anemia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple epiphyseal dysplasia", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic calcification", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent spontaneous abortion", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocerebellar cyst", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small forehead", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spondylometaphyseal dysplasia", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous pneumothorax", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Stapes ankylosis", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth abscess", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Usual interstitial pneumonia", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANXA11", "AP1B1", "AP1S1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARPC1B", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATRX", "ATXN10", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAT2", "BCKDHB", "BCKDK", "BCOR", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALD1", "CALR", "CAMK2G", "CAPN1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBFB", "CBL", "CC2D1A", "CCDC22", "CCDC47", "CCNK", "CCT5", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CENPE", "CENPF", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN6", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNP", "COA3", "COA7", "COASY", "COG1", "COG5", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ5", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CUL7", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDHD2", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC19", "DNAJC21", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK6", "DOCK7", "DPAGT1", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "ENPP1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "FAH", "FAM126A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKB", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IQCB1", "IRAK1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ITCH", "ITM2B", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5C", "KDSR", "KIAA0319L", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF7", "KIFBP", "KMT2A", "KNL1", "L2HGDH", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "LZTFL1", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP3K7", "MAPK1", "MAPKAPK3", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", "MED13", "MED17", "MED23", "MED25", "MESD", "MFF", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOCOS", "MOGS", "MORC2", "MPG", "MPI", "MPP5", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NARS2", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NEMF", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OSGEP", "OSTM1", "OTUD6B", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLCB3", "PLCG2", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPIP5K2", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RAD54B", "RALA", "RALGAPA1", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF2", "RP2", "RPIA", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRM2B", "SACS", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SBF1", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC33A1", "SLC39A14", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STIM1", "STT3A", "STUB1", "SUCLA2", "SUCLG1", "SUZ12", "SYNE1", "SYNE2", "TAF15", "TAF6", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCOF1", "TECR", "TELO2", "TENM3", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TKFC", "TKT", "TLK2", "TMCO1", "TMEM126A", "TMEM165", "TMEM199", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRIM28", "TRIP11", "TRIP12", "TRIP13", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSPYL1", "TSR2", "TTC19", "TTC21B", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP4", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBA5", "UBE3A", "UBE4A", "UBE4B", "UBR7", "UBTF", "UFC1", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VIPAS39", "VPS13A", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR26", "WDR36", "WDR4", "WDR45B", "WDR48", "WDR73", "WFS1", "WIPI2", "WNK1", "XIAP", "XPNPEP3", "XRCC1", "XRCC4", "YARS", "YARS2", "YEATS2", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF687", "ZPR1"], "leading_proteins": ["AAAS", "ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD1", "ABCD4", "ABHD12", "ACADVL", "ACBD5", "ACOX1", "ACTN1", "ACTN4", "ADA", "ADD3", "ADNP", "AFG3L2", "AGK", "AIFM1", "AIP", "AKAP9", "ALDH18A1", "ALDH3A2", "ALG1", "ALG11", "ANAPC1", "ANKLE2", "ANO10", "AP1B1", "AP2S1", "AP3B1", "APOL2", "APP", "ARV1", "ASAH1", "ASNA1", "ATAD3A", "ATP1A1", "ATP2A2", "ATP2B4", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATXN10", "B4GALT1", "B4GAT1", "BAZ1B", "BCAP31", "BCKDHB", "BCS1L", "BICD2", "BRAT1", "BRD4", "BUD23", "C19orf70", "C1QBP", "CARS", "CASK", "CASP8", "CC2D1A", "CCDC22", "CCDC47", "CDC45", "CDK4", "CENPE", "CERS1", "CHMP1A", "CHMP2B", "CHST14", "CLCC1", "CLCN6", "CLCN7", "CLN5", "CLPP", "CNNM4", "CNOT1", "COA3", "COA7", "COASY", "COG1", "COG5", "COG7", "COLEC12", "COMT", "COQ5", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPT1A", "CPT2", "CRTAP", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "DARS2", "DCTN1", "DCTN4", "DDB1", "DDRGK1", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DNA2", "DNAAF5", "DNAJB11", "DNAJC3", "DNM1L", "DNM2", "DPAGT1", "DPH1", "DST", "DYM", "DYNC2H1", "EBP", "ECE1", "EFNB1", "EHMT1", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF4H", "EMD", "ENPP1", "EPHX2", "EPS15L1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN2", "ESS2", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXT2", "FAH", "FANCD2", "FANCI", "FAR1", "FARSA", "FASN", "FDFT1", "FECH", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLII", "FMR1", "FOXRED1", "FTO", "FUCA1", "FUS", "FXR1", "GAA", "GALNT2", "GBA", "GDAP1", "GGCX", "GLA", "GLB1", "GM2A", "GNA11", "GNAO1", "GNPAT", "GNS", "GOSR2", "GPAA1", "GPD2", "GSS", "GTPBP3", "GUSB", "HADH", "HCCS", "HEXA", "HEXB", "HIKESHI", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HPS6", "HS2ST1", "HYOU1", "IARS2", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IMPAD1", "INTS1", "IQCB1", "ITM2B", "JAGN1", "KDM1A", "KDSR", "KIAA0319L", "KIF11", "KIF14", "KIF7", "KIFBP", "KMT2A", "L2HGDH", "LAMP2", "LARS", "LBR", "LDLR", "LEMD2", "LEMD3", "LETM1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LRBA", "LRP1", "LRP2", "MAN2B1", "MAPRE2", "MATR3", "MBOAT7", "MCM4", "MCM6", "MCM7", "MED25", "MFF", "MFN2", "MIA3", "MICU1", "MOGS", "MRPS22", "MRPS25", "MSH2", "MSMO1", "MTAP", "MTCH1", "MTOR", "MTX2", "MYH14", "MYO5A", "NAGLU", "NCAPG2", "NCSTN", "ND1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NEDD4L", "NEFL", "NIPBL", "NNT", "NONO", "NPC1", "NPC2", "NSD2", "NT5C2", "NUP107", "NUP160", "NUP37", "NUP93", "OCLN", "OPA1", "OPA3", "OSTM1", "OTUD6B", "P3H1", "P4HA2", "P4HB", "PANX1", "PCBD1", "PCK2", "PDHB", "PDK3", "PDP1", "PDSS2", "PEX14", "PEX19", "PEX3", "PEX5", "PGM3", "PHKA1", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PISD", "PITRM1", "PLAA", "PLCG2", "PLD3", "PLEC", "PLOD1", "PMPCA", "PNPLA6", "PNPLA8", "POLE", "PON2", "POR", "PPP2R1A", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRKCSH", "PRKRA", "PRPF3", "PSAP", "PSMB4", "PTRH2", "PUF60", "PUS1", "PXMP2", "QDPR", "RAB18", "RAD21", "RALA", "RANGRF", "RBM10", "RBM8A", "RBMX", "RDH11", "REEP2", "REPS1", "RFC2", "RFT1", "RINT1", "RIPK1", "RMND1", "RNASET2", "RNF2", "RPS6KA3", "RRAS2", "RRM2B", "SAR1B", "SC5D", "SCARB2", "SCO1", "SCO2", "SDHB", "SEC31A", "SEC63", "SET", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SIGMAR1", "SIL1", "SLC12A2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC33A1", "SLC39A14", "SMARCC2", "SMARCE1", "SMC1A", "SMC3", "SNAP29", "SON", "SPART", "SPEN", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SSBP1", "SSR4", "STAG1", "STAG2", "STARD7", "STIM1", "STT3A", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TAP1", "TBL2", "TECR", "TELO2", "TFG", "TFRC", "TIMM22", "TIMM8A", "TIMMDC1", "TMCO1", "TMEM126A", "TMEM165", "TMEM199", "TMEM43", "TMEM70", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOMM40", "TOR1AIP1", "TPM1", "TPM3", "TPP1", "TRAPPC11", "TRIP11", "TRMU", "TRRAP", "TSC2", "TTC19", "TTC37", "TUBGCP2", "TUBGCP4", "TWNK", "TXNDC15", "UBE3A", "UBE4B", "UQCRC2", "UQCRQ", "USMG5", "VAMP7", "VANGL1", "VIM", "VIPAS39", "VPS13A", "VPS16", "VPS33B", "VPS51", "WASHC5", "WBP11", "WFS1", "YARS2", "YIPF5", "YME1L1", "YWHAE", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_kegg/advanced/idx2term.json b/msigdb_kegg/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..09d2ad624c5a1814aee291e16ea0306487976511 --- /dev/null +++ b/msigdb_kegg/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Lysosome", "1": "Sphingolipid metabolism", "2": "Snare interactions in vesicular transport", "3": "Cardiac muscle contraction", "4": "Abc transporters", "5": "Calcium signaling pathway", "6": "Steroid biosynthesis", "7": "Parkinsons disease", "8": "Cell adhesion molecules cams", "9": "Oxidative phosphorylation"} \ No newline at end of file diff --git a/msigdb_kegg/advanced/plot_0.png b/msigdb_kegg/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d1e010eb012975f059a805cd2d7b1c70745ce34c --- /dev/null +++ b/msigdb_kegg/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a90bc755a0c8f1d13d3e58168772c8d46a5c54b175f90640387f03c3b14c6f24 +size 197852 diff --git a/msigdb_kegg/advanced/plot_1.png b/msigdb_kegg/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..cc2176e1e2c19b77e450676cb116ef530bcf6fed --- /dev/null +++ b/msigdb_kegg/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c54a334e9e9880f354799df7bc06e68ce9629022c6a743821c724a57cdc42cb +size 190908 diff --git a/msigdb_kegg/advanced/plot_2.png b/msigdb_kegg/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..3bbb4fa67c5a9345d7fab03a2188a6e0dabd0cf9 --- /dev/null +++ b/msigdb_kegg/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90034be525a0c34e201400946fd4b8af7b93ba25350ed71cd9a913ce2efcb4b3 +size 191031 diff --git a/msigdb_kegg/advanced/plot_3.png b/msigdb_kegg/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..93d76c9b6784635eae0e9781294ce58d731b9f71 --- /dev/null +++ b/msigdb_kegg/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d839e2d6670819678cd0fd6ce4f5a3d95878e9f8c860c9f5570eb53ed30557c5 +size 196390 diff --git a/msigdb_kegg/advanced/plot_4.png b/msigdb_kegg/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..9f20abbf9b0aa15689ab704c82829bd93e53f8fe --- /dev/null +++ b/msigdb_kegg/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9a92228ec0972bb3c3820c2a48fe4b5ec0dd8053f377afd44a4f76de9191634 +size 184718 diff --git a/msigdb_kegg/advanced/plot_5.png b/msigdb_kegg/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..287af90034c60471e9f93c3375cd65f1b61838f7 --- /dev/null +++ b/msigdb_kegg/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e327d85a9fca4744bf8c8eb9ef6fee72a90b6c9cc1d6ff57890d7bc70a546bc +size 197691 diff --git a/msigdb_kegg/advanced/plot_6.png b/msigdb_kegg/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..5864d89929a4c20c3cda17182a626beb6c2de590 --- /dev/null +++ b/msigdb_kegg/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:feeb2aca13be4ed92e78e0ab1382ebd7a24c283fd3673967930a94f9d6f0403f +size 192239 diff --git a/msigdb_kegg/advanced/plot_7.png b/msigdb_kegg/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..445ec7ed89c280872a748d82c717e7cb6c123e05 --- /dev/null +++ b/msigdb_kegg/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:166aa5ff83df9dce6cd5b7ff84825c3f4312c7cdb08a032b279ce23856543f55 +size 206996 diff --git a/msigdb_kegg/advanced/plot_8.png b/msigdb_kegg/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..14a2883ea293a1dd127d6c62121b883bb524e1dc --- /dev/null +++ b/msigdb_kegg/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:303b968b2243147024f590528282c58ea650db11ebb5124aa4085cc2d08829f0 +size 192392 diff --git a/msigdb_kegg/advanced/plot_9.png b/msigdb_kegg/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..f161eab823dcd921084e24cab30149b96946d602 --- /dev/null +++ b/msigdb_kegg/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:598f1a0b7afd2d10a99e8adaaa06eada60e402e5f79117763998503db78e4238 +size 209854 diff --git a/msigdb_kegg/basic/idx2term.json b/msigdb_kegg/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..02b0922490f352e2c691bf2e4a4902a7afbf9d62 --- /dev/null +++ b/msigdb_kegg/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Lysosome", "1": "Sphingolipid metabolism", "2": "Snare interactions in vesicular transport", "3": "Cardiac muscle contraction", "4": "Abc transporters", "5": "Calcium signaling pathway", "6": "Steroid biosynthesis", "7": "Parkinsons disease", "8": "Cell adhesion molecules cams", "9": "Oxidative phosphorylation", "10": "Hypertrophic cardiomyopathy hcm", "11": "N glycan biosynthesis", "12": "Antigen processing and presentation", "13": "Glycerophospholipid metabolism", "14": "Protein export", "15": "Huntingtons disease", "16": "Vibrio cholerae infection", "17": "Alzheimers disease", "18": "Arrhythmogenic right ventricular cardiomyopathy arvc", "19": "Peroxisome", "20": "Biosynthesis of unsaturated fatty acids"} \ No newline at end of file diff --git a/msigdb_kegg/basic/plot_0.png b/msigdb_kegg/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..477d41b87f977b26de608c48123c337e83b60b15 --- /dev/null +++ b/msigdb_kegg/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:20aa90137581a1f010eacb44ea42d90ce68a468ae197d6dec426ad59f0e4bc1b +size 138453 diff --git a/msigdb_kegg/basic/plot_1.png b/msigdb_kegg/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..1f2cd437198f4c7366b730e741a26d6c425b1c00 --- /dev/null +++ b/msigdb_kegg/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6afb0b9d4670c83aff2a5d7fd0c1e74c7102401066cbeab29aaf154e197b0ead +size 144311 diff --git a/msigdb_kegg/basic/plot_10.png b/msigdb_kegg/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..b398be0a8aefba522f6058ec42ec895ffa21b977 --- /dev/null +++ b/msigdb_kegg/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84f24e295f0dc51691446e255ab30a4913f9ff49f29cc032dbe1ec54dc158d14 +size 139848 diff --git a/msigdb_kegg/basic/plot_11.png b/msigdb_kegg/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..2e95e1ff582450b8e54630ba1f1eab35a3527cbd --- /dev/null +++ b/msigdb_kegg/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:348436e6c8b70efe127408624d4c301fb3c187c593384dceea3a528cd9461cab +size 133149 diff --git a/msigdb_kegg/basic/plot_12.png b/msigdb_kegg/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..fbcbefaadfbdc3f13d2d3f7a1cc07f20f96fb0e5 --- /dev/null +++ b/msigdb_kegg/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c1bc8d6d9605a740a371761a76ce933f6356cc8f6904d814f584a01f108b685 +size 140488 diff --git a/msigdb_kegg/basic/plot_13.png b/msigdb_kegg/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..fffa2708c96ca15fd2107d6aa7e4bf2f99b74bcb --- /dev/null +++ b/msigdb_kegg/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d50482ecd9684bc17203065d14f1214d7fdf230bf91bb4184deda4be2ea6f74 +size 139351 diff --git a/msigdb_kegg/basic/plot_14.png b/msigdb_kegg/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..94d071d39a2c44c5177b68ad270fcb956d99c41e --- /dev/null +++ b/msigdb_kegg/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c679f8c42c5f52890471457433e94f632d62113e6a053cde7d57a84380ab95a +size 138817 diff --git a/msigdb_kegg/basic/plot_15.png b/msigdb_kegg/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..471e27e0c671d22a1c645dc982e93dc33d2b6ff2 --- /dev/null +++ b/msigdb_kegg/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d5519a7869e2ac78b87f5dd54022ee1d06cd59cfe4eea2e9fc4f37fa5367682 +size 141272 diff --git a/msigdb_kegg/basic/plot_16.png b/msigdb_kegg/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..a6b9bf3361ff95d2007e9005ff8d047d5b9765d5 --- /dev/null +++ b/msigdb_kegg/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d0c46d083e7995f50d83ae70e1e80419e963088b522c5605420cee48650db5e +size 143972 diff --git a/msigdb_kegg/basic/plot_17.png b/msigdb_kegg/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..43d4d40d4ab2bbb333c932d0b6a8ec36502e8173 --- /dev/null +++ b/msigdb_kegg/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed1b0f3e0426223627ee8bbfd9f1b63836bf0357d32617ca7096601d072014b6 +size 145785 diff --git a/msigdb_kegg/basic/plot_18.png b/msigdb_kegg/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..ac22d8c909d8b305c4c42493c9d2c9b2a8735406 --- /dev/null +++ b/msigdb_kegg/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3f927334437ae03ae70d79219c40e4979c1959f3c5d80f081784d73e35ad9a5a +size 148135 diff --git a/msigdb_kegg/basic/plot_19.png b/msigdb_kegg/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..a81d12ef9886784486c8eebb4b015d9f66c74b2f --- /dev/null +++ b/msigdb_kegg/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:437509832b0e62f3f27b4c2b810a66572eee209ceed3af3f3c59bec021fbb4cb +size 141632 diff --git a/msigdb_kegg/basic/plot_2.png b/msigdb_kegg/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..600e7a4fe243228b33268ee42ddad0b4fd2de850 --- /dev/null +++ b/msigdb_kegg/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce8059e96fa982fa4822bff12d9c8fc17fb02e4f14ccee3a73bf938325f44644 +size 147448 diff --git a/msigdb_kegg/basic/plot_20.png b/msigdb_kegg/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..c59b26d7e601b0a72b938fa4feab42b46013f3ab --- /dev/null +++ b/msigdb_kegg/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14529af47be2636ca27451e3675c00efa31f2a176e0bcfda03438e1903607313 +size 149407 diff --git a/msigdb_kegg/basic/plot_3.png b/msigdb_kegg/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..8c71cf31f27d82a2f0731050aa4a34f16329ef85 --- /dev/null +++ b/msigdb_kegg/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cfd476e82cf0c76e77ae2bc92ddebfab50149c4e43ed9468493d0cfe9c057947 +size 139665 diff --git a/msigdb_kegg/basic/plot_4.png b/msigdb_kegg/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..92332b3455a56fc6eff5d7a707a8b62de6cdf6ab --- /dev/null +++ b/msigdb_kegg/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52e57c5a5837307ffcec26584dda83dc778168ea0cd07b764cfb9ce8b708312b +size 138195 diff --git a/msigdb_kegg/basic/plot_5.png b/msigdb_kegg/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..a754f65248157850fefa13e6c37ad29902ce0d15 --- /dev/null +++ b/msigdb_kegg/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:982e76eb244bc0c673e150631f969134840b284766d977ffb6af1c2f916a6a3c +size 145034 diff --git a/msigdb_kegg/basic/plot_6.png b/msigdb_kegg/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..e1344f0b18d474c798ca3c16a32d7e41d3d742e6 --- /dev/null +++ b/msigdb_kegg/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5a905ac87604b9155e089e8dce866f851ed576e587d8ce46f00c5b66f9cd9321 +size 138760 diff --git a/msigdb_kegg/basic/plot_7.png b/msigdb_kegg/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..816bfaa2d3d779a9a579c40ec725a9b4edc70300 --- /dev/null +++ b/msigdb_kegg/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb3fb5ea42c1974e55fa717d22da2243ccb19fc3606508cd3ee08ff7240b66b4 +size 141271 diff --git a/msigdb_kegg/basic/plot_8.png b/msigdb_kegg/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..5e490f4dd28edebc2c4722a0b1ca7b8d86bf3f3e --- /dev/null +++ b/msigdb_kegg/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12ac88374b968581269b1efeb559637be54fe0fc0935bd5d4cdc3da3f82bb115 +size 140275 diff --git a/msigdb_kegg/basic/plot_9.png b/msigdb_kegg/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..6fa2933fd728d311687c98703f46a5d3574069ae --- /dev/null +++ b/msigdb_kegg/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae1cdceb3cc51b972ed1527bb612ea42d213172ba7608b1938bac18c2b76b7a7 +size 139515 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d7cf80f181017b9bf9c9074dcdfc132fab9e02a1 --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f45083eded41bec2d7fb590c68032bbe74bfbdfb5070741b64b9047527c85d5 +size 100412 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6661dd695ae26f47684daafa60927b2620a43f83 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 27 51 4.336382391445374 1.4484687063776036e-05 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 5.180140351236238e-13 0.0011728813459652 4.553595339527414e-06 1.334930800029769e-08 7.196331786019585e-13 +Sphingolipid metabolism 9 13 3.205648448483894 0.0013475851640678 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 1.2802833229834784e-06 0.1114021565620111 0.2147385524083838 0.0002861885476851 1.4416472873703857e-06 +Snare interactions in vesicular transport 11 16 3.167786788913157 0.0015360412561356 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.0001974885348412 1.0 0.2872333566147377 0.0097601039903573 0.000217728528826 +Cardiac muscle contraction 13 21 3.0649092850622583 0.0021773602833252 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.0052037962080083 0.018891152845815 0.0008840144918394 0.0044406378118471 0.0056200963406339 +Abc transporters 9 12 2.827951266938664 0.0046846937371365 2.3762135922330097 6.366504854368932 0.6645221155900782 0.3307647417699358 1.8079428939478197 2.1798157082242287 1.1702884010083077 0.2791394174824396 0.0681744237474234 1.0 1.0 0.0834574734746242 0.0705348016344186 +Calcium signaling pathway 10 22 2.7912712962250272 0.0052501446043529 5.735436893203883 16.946601941747574 1.0005800740695592 0.3113014190776675 2.984654368989517 2.3866666657890168 1.2450167285670062 0.3187454651207294 0.0009756192602542 1.0 0.4672829604777532 0.0723728978816966 0.0010872803465048 +Steroid biosynthesis 6 12 2.7297449028569925 0.0063383350841836 4.451456310679611 10.919902912621358 0.8535439655720318 0.1867209176898754 2.1463612955879627 1.3314318120676296 1.5430058140543457 0.1933818217769055 2.5492382212206986e-05 1.0 0.1265462710440741 0.0041946485896371 2.763867591720716e-05 +Parkinsons disease 19 57 2.589376950275273 0.009614977917931 16.90776699029126 54.04126213592233 1.0315348591123816 0.3152611195514452 7.595108151251147 4.223805209268991 1.8494970521239744 0.3626807692210581 7.108886051530569e-08 0.0013587494764046 6.1280090098085e-06 1.114101386375826e-06 8.977670650668214e-08 +Cell adhesion molecules cams 7 14 2.319830302939213 0.0203500591106817 4.043689320388349 9.91019417475728 0.3640395302172229 0.4325707543794381 2.3114392567097153 2.512916721209252 1.1817978240178808 0.3174557953274378 0.1156615300782399 1.0 1.0 1.0 0.1208874805839759 +Porphyrin and chlorophyll metabolism 3 14 2.318555914695548 0.0204191278436816 3.728155339805826 13.315533980582524 1.2215621624941897 0.2689555702886888 1.770547470360957 1.4201912411596824 1.0389071586082248 0.2908939383930566 0.0021155878345267 0.0039064712270754 0.0008717411361388 0.0011993766429203 0.002252196025852 +Other glycan degradation 4 7 2.2301679433456547 0.0257362955686224 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 0.0003469428870386 1.0 1.0 0.0041946485896371 0.0003706302782608 +Oxidative phosphorylation 21 63 2.22541541488523 0.0260533636622144 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 1.3507630245335778e-08 0.0001157398459272 6.1280090098085e-06 1.114101386375826e-06 1.7321510409889415e-08 +Glycosaminoglycan degradation 4 6 2.1576906782039376 0.0309518891961242 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 0.0001486934237484 1.0 1.0 0.0328731354880699 0.0001590313802548 +Hypertrophic cardiomyopathy hcm 5 11 1.986234649837852 0.0470072751045236 3.429611650485437 9.101941747572816 0.6486134300733651 0.4298239576137608 1.8675556020784376 1.719193792909202 1.0005513529453438 0.3180395638112931 0.6051032616602514 1.0 1.0 1.0 0.612992755958387 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b81d0ab97e3e327276aaded934997167d40819a0 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 18.144444444444446 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..21e15f8581dcf880e4f463414f361f044cec6d5d --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..689ac80b9647bdb28b72b74e56874d53637e4189 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,55 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.692063192740359 4.336382391445374 1.4484687063776036e-05 0.0026038665972282 0.0021740263654912 51 Q93050,P13473,Q9NZJ7,P50897,Q9UMR5,P06280,P16278,Q9BXS5,P17900,P04062,P54802,Q13510,P06865,O15118,O14773,O75503,P07602,P10253,O00754,P11279,Q9Y487,P10619,P08236,Q8NCC3,Q15904,Q14108,P15586 27 +Sphingolipid metabolism 0.7922221064659877 3.205648448483894 0.0013475851640678 0.2155158533477769 0.0242565329532214 13 Q06136,O95470,P04062,Q13510,Q16739,Q16880,P06280,O15269,P16278 9 +Snare interactions in vesicular transport 0.7297079945108964 3.1677867889131575 0.0015360412561356 0.241718046246101 0.0251352205549462 16 O95249,O43752,O14653,Q12981,O60499,O15498,Q9P2W9,O15400,O95721,Q86Y82,Q13190 11 +Cardiac muscle contraction 0.6519539040900368 3.0649092850622583 0.0021773602833252 0.3245337948186345 0.032660404249879 21 Q9UDW1,P16615,O14548,P20674,P15954,O14949,P00403,P09493,P22695,P05026,P13073,P14406,P05023 13 +Abc transporters 0.7505334296897186 2.827951266938664 0.0046846937371365 0.5705398117681044 0.052702804542786 12 P33897,Q99758,O75027,Q03518,O14678,P08183,Q9NP58,P33527,O15439 9 +Calcium signaling pathway 0.6011492768892505 2.7912712962250272 0.0052501446043529 0.612296926833492 0.0555897663990308 22 P12235,P45880,P16615,P12236,P20020,P21796,P23634,P46020,Q9Y277,P05141 10 +Steroid biosynthesis 0.7328405011208907 2.7297449028569925 0.0063383350841836 0.6816269182294676 0.060047385008056 12 Q16850,O75845,Q14534,Q15125,Q15800,Q15392 6 +Parkinsons disease 0.5043040793995829 2.589376950275273 0.009614977917931 0.8243162978900482 0.0721123343844831 57 Q9UDW1,O14949,P00846,O43676,O95139,O14548,P00403,P12236,P21912,P06576,Q9Y277,P03886,P13073,P21796,P14406,O96000,P12235,P45880,P24539 19 +Cell adhesion molecules cams 0.6166422382243893 2.319830302939213 0.0203500591106817 0.9752961301790768 0.1225147670620896 14 P06756,Q16625,Q92896,P01889,P10321,P04439,Q92859 7 +Porphyrin and chlorophyll metabolism 0.6164419370085459 2.3185559146955477 0.0204191278436816 0.9756076677725586 0.1225147670620896 14 P22830,P09601,P30519 3 +Other glycan degradation 0.756936340960765 2.2301679433456547 0.0257362955686224 0.990842556916752 0.1339887274056743 7 Q9BTY2,P04062,P06865,P16278 4 +Oxidative phosphorylation 0.4719064345380046 2.22541541488523 0.0260533636622144 0.9913636712447624 0.1339887274056743 63 Q9UDW1,Q86Y39,Q93050,O14949,P00846,O43676,O95139,P56385,O14548,O75964,P00403,P21912,P06576,P03886,P13073,Q9Y487,P14406,O96000,Q15904,Q7KZN9,P24539 21 +Glycosaminoglycan degradation 0.8029627477619392 2.1576906782039376 0.0309518891961242 0.9965153347951802 0.1466142119816411 6 P16278,P54802,P15586,P06865 4 +Hypertrophic cardiomyopathy hcm 0.630797939126843 1.9862346498378516 0.0470072751045236 0.9998277634380404 0.1800278621024309 11 P06756,P54619,P16615,P50402,P09493 5 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.6870488165943571 1.8820513019792589 0.059829050427524 0.9999849606524444 0.1974280986292688 7 O43292,Q9H490,Q5H8A4 3 +O glycan biosynthesis 0.8473571700335039 1.8792801730023376 0.0602062474813287 0.9999860086489472 0.1974280986292688 4 O43505,Q8N4A0 2 +N glycan biosynthesis 0.4932142300279185 1.8106056363007312 0.0702019191082381 0.99999795846804 0.2256490257050511 20 Q9H3H5,Q2TAA5,P15291,P04844,O60476,P04843,Q9BT22,P46977,Q16706,P26572,Q86YN1,Q96AA3 12 +Nicotinate and nicotinamide metabolism 0.722268615300057 1.7835433039144637 0.074497905387588 0.999999112980681 0.2338807001990134 6 P43490,P22413,Q9BQG2,Q13423 4 +Glycosphingolipid biosynthesis ganglio series 0.8233456944002712 1.7782575859187997 0.0753615589530154 0.99999925019198 0.2338807001990134 4 O00400,P16278 2 +Autoimmune thyroid disease 0.807898448519042 1.7128512711998185 0.0867399048996677 0.999999919275255 0.2518255303538741 4 P01889,P10321,P04439 3 +Allograft rejection 0.807898448519042 1.7128512711998185 0.0867399048996677 0.999999919275255 0.2518255303538741 4 P01889,P10321,P04439 3 +Graft versus host disease 0.807898448519042 1.7128512711998185 0.0867399048996677 0.999999919275255 0.2518255303538741 4 P01889,P10321,P04439 3 +Antigen processing and presentation 0.4973866776486086 1.6938122840689085 0.0903009590904133 0.9999999600430224 0.2539714474417875 17 P27824,Q9UL46,P10321,Q03518,P61289,P04439,Q99538 7 +Ecm receptor interaction 0.7183190975885587 1.544287626323844 0.1225186688259341 0.9999999999393516 0.303024525968976 5 Q08722,P06756 2 +Glycerophospholipid metabolism 0.4715537975098679 1.542742441050183 0.1228932799763069 0.9999999999438384 0.303024525968976 18 O15228,Q96N66,O14735,Q8NCC3,Q92604,Q9HCL2,Q8NF37,Q9UG56,Q9HBU6,O95674 10 +Protein export 0.4835479158322777 1.534669615796154 0.1248650029264752 0.9999999999625452 0.3037256827941291 16 Q9UHB9,P49458,Q9Y5M8,P67812,Q15070 5 +Huntingtons disease 0.4110063362879973 1.496839274159831 0.1344350843209523 0.9999999999948248 0.3226442023702855 83 Q9UDW1,O14949,Q9UJW0,P00846,O43676,O95139,O14548,P00403,P12236,P21912,P06576,Q9Y277,P13073,P21796,P14406,O96000,P12235,P45880,P24539 19 +Vibrio cholerae infection 0.3956401181347513 1.349048321167511 0.1773214458464083 0.9999999999999994 0.3930609903268696 25 Q93050,P24390,Q15904,O43731,Q9Y487 5 +Steroid hormone biosynthesis 0.8635466591485719 1.336932135703051 0.1812447899840565 0.9999999999999998 0.3930609903268696 2 P21964 1 +Renin angiotensin system 0.7121980609256231 1.3022089958418657 0.1928449508184531 1.0 0.4132391803252566 4 P10619 1 +Alzheimers disease 0.3829137426766696 1.2422132771690049 0.2141578822227965 1.0 0.4448878073978873 64 O95139,Q92542,Q9UDW1,O14548,O14949,P00403,P21912,P00846,P13073,O43676,P05067,P14406,P06576,O96000,P24539 15 +Glycosphingolipid biosynthesis lacto and neolacto series 0.8370453904708132 1.2266911142441923 0.2199387087105762 1.0 0.4448878073978873 2 O43505 1 +Glycosaminoglycan biosynthesis keratan sulfate 0.8370453904708132 1.2266911142441923 0.2199387087105762 1.0 0.4448878073978873 2 O43505 1 +Glycosaminoglycan biosynthesis heparan sulfate 0.686590752100739 1.1915694032301911 0.2334301281311248 1.0 0.4448878073978873 4 O94923,Q7LGA3 2 +Folate biosynthesis 0.6747251869882678 1.1403581046101303 0.2541371396177641 1.0 0.4543999584178556 4 P00374 1 +Amyotrophic lateral sclerosis als 0.470505233819031 1.028765709397709 0.3035897838791239 1.0 0.4879121526628777 11 P07197,Q9BUN8 2 +Type i diabetes mellitus 0.5996054716120338 1.0041163787048268 0.3153225216669011 1.0 0.5022836628322319 5 P01889,P10321,P04439 3 +Glycosphingolipid biosynthesis globo series 0.7632736649674892 0.918784775430018 0.3582081572619686 1.0 0.5565824751302197 3 P06280 1 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.4213444865832028 0.9133285870971672 0.361069751698077 1.0 0.5565824751302197 13 P06756,O43707,P16615,P50402,P02545 5 +Alpha linolenic acid metabolism 0.7569091934574166 0.8946550451503605 0.3709715168792402 1.0 0.5658887545615529 3 O95864,Q15067 2 +Dilated cardiomyopathy 0.4579835237612998 0.8561961521097615 0.3918892906263231 1.0 0.57349652286779 10 P09493,P06756,P16615,P50402 4 +Proximal tubule bicarbonate reclamation 0.444522004285792 0.7419976632935772 0.4580887513569966 1.0 0.6294349255286977 8 Q16822,Q9UBX3,P05023 3 +Riboflavin metabolism 0.4908383398421349 0.6717538552660015 0.5017404097820153 1.0 0.6640681894173732 6 P22413,Q9NPH0 2 +Mtor signaling pathway 0.3512946399717505 0.5843985965973673 0.5589521707323071 1.0 0.7085309206465864 16 P51812,Q15418,P42345 3 +Aldosterone regulated sodium reabsorption 0.3836908598378287 0.4496605336453939 0.6529552328152448 1.0 0.7969977737092703 9 Q96PU5,O14654,P05026,P05023 4 +Peroxisome 0.2839349489596622 0.4301484179819578 0.667087681359176 1.0 0.8058777358701456 37 P33897,O75381,O43808,Q9BY49,Q9NR77,O14678,Q9BQG2,P40855,Q9UKU0 9 +Basal transcription factors 0.3694700526086518 0.3792867871577717 0.7044749102820687 1.0 0.8305436603476232 9 P29083,Q9Y6J9 2 +Galactose metabolism 0.3170256298833988 0.3263324473074559 0.7441728413400077 1.0 0.841782916634691 14 P10253,P52789,P16278,P06280 4 +Viral myocarditis 0.3327075279082063 0.3147808492282183 0.7529280532121403 1.0 0.841782916634691 12 P01889,P10321,P04439 3 +Starch and sucrose metabolism 0.3101413904263531 0.2875552192456277 0.7736872274348374 1.0 0.8572736226792561 14 P10253,P52789,P08236 3 +Biosynthesis of unsaturated fatty acids 0.3273876634615493 0.2330089091754154 0.8157544876431131 1.0 0.8899139865197597 11 O15254,O95864,Q53GQ0,Q15067,Q9BY49,Q9NZ01,O60427 7 +Arachidonic acid metabolism 0.3780789307846759 0.1419717945270537 0.8871022846898637 1.0 0.9337918786209092 5 Q9UJ14 1 +Phosphatidylinositol signaling system 0.2590000080689371 0.04888127772292 0.9610139092369 1.0 0.999898865101977 15 O14735,Q10713,Q8TBX8 3 +Long term depression 0.2483171470938797 0.0087117902854231 0.9930490849580385 1.0 1.0 14 P30154 1 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6a3530c205e5ca2b81a4a865d4da1300cb1d7547 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEX1", "APP", "APPL1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATRX", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCKDHB", "BCR", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC15", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERA", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPAGT1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "ESPL1", "ETNK1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS1", "FADS2", "FAH", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA2", "GGCT", "GGH", "GGT7", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTSE1", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPDH1", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "JAM3", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "L2HGDH", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAD1L1", "MAD2L1", "MAGED1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGAT1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPP5", "MPST", "MPV17", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTOR", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYL6", "NAA16", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NBN", "NCBP1", "NCBP2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEO1", "NGEF", "NIT2", "NLN", "NLRX1", "NME1", "NME3", "NNT", "NPC1", "NPC2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NT5C2", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCLN", "OCRL", "OGDH", "ORC3", "ORC5", "OXA1L", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK3", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDSS1", "PDSS2", "PECR", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PHKA1", "PHKB", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCB3", "PLCG1", "PLCG2", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNB2", "PMPCA", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTDSS1", "PTGES2", "PTK2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PVR", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB13", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RALA", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFT1", "RHOA", "RICTOR", "RIPK1", "RNASEH2A", "RNASEH2C", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRM1", "RRM2", "RRM2B", "RSL24D1", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SETD1A", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC33A1", "SLC38A2", "SLIT2", "SLK", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPHK2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STMN1", "STT3A", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SV2A", "SYMPK", "SYVN1", "TAB1", "TAF6", "TAF6L", "TAF7", "TALDO1", "TAP1", "TARS", "TARS2", "TARSL2", "TBPL1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TOLLIP", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSPO", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UCK2", "UGCG", "UGDH", "UGP2", "UGT8", "ULBP3", "ULK3", "UMPS", "UNC45A", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "USP8", "VAMP7", "VANGL1", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS28", "VPS37B", "VPS4A", "VPS4B", "VTA1", "WARS", "WBP11", "WDR61", "XAB2", "XIAP", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ACOX1", "ACOX3", "ACP6", "ACSL6", "ACTN4", "ALG1", "ALG11", "AP1M1", "APP", "ASAH1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "B4GALT1", "B4GAT1", "BNIP1", "CANX", "CD47", "CDIPT", "CDS2", "CLN5", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "COX7C", "CTSA", "CYP51A1", "DCTN4", "DERL1", "DHCR24", "DHFR", "DOLPP1", "DPAGT1", "EBP", "EMD", "ENPP1", "ETNK1", "FADS1", "FADS2", "FECH", "FUCA2", "GAA", "GALNT4", "GBA", "GGT7", "GLA", "GLB1", "GLCE", "GLG1", "GM2A", "GNPAT", "GNS", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GTF2E1", "GUSB", "HEXA", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HS2ST1", "HSD17B12", "IRS4", "ITGAV", "KDELR1", "KDELR3", "KDSR", "LAMP1", "LAMP2", "LGMN", "LMNA", "LPCAT1", "LPGAT1", "MAN1A2", "MAN2A1", "MAN2B1", "MBOAT7", "MGAT1", "MSMO1", "MTCH1", "MTOR", "NAGLU", "NAMPT", "NCSTN", "ND1", "NDUFA11", "NDUFB10", "NDUFB3", "NDUFB6", "NEDD4L", "NEFM", "NEO1", "NNT", "NPC1", "NUDT12", "OCLN", "OXA1L", "PCK2", "PECR", "PEX14", "PEX19", "PHKA1", "PIGG", "PIGU", "PIP4K2C", "PISD", "PLA2G15", "PMPCA", "PPP2R1B", "PPT1", "PPT2", "PRKAG1", "PSAP", "PSME2", "PSME3", "PXMP2", "RFT1", "RPN1", "RPN2", "RPS6KA1", "RPS6KA3", "SC5D", "SCARB2", "SDHB", "SEC11A", "SGPL1", "SLC25A10", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC33A1", "SNAP29", "SPTLC1", "SQLE", "SRP68", "SRP9", "SRPRB", "STT3A", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "TAF6L", "TAP1", "TECR", "TPM1", "TPP1", "UGCG", "UGT8", "UQCR10", "UQCRC2", "UQCRQ", "VDAC1", "VDAC2", "VDAC3", "YKT6"]} \ No newline at end of file diff --git a/msigdb_reactome/advanced/idx2term.json b/msigdb_reactome/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a06831e8cf2f0e807cd19bfbc138b8946adaf4e4 --- /dev/null +++ b/msigdb_reactome/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport of small molecules", "1": "Sphingolipid metabolism", "2": "Mitochondrial protein import", "3": "Slc mediated transmembrane transport", "4": "Glycosphingolipid metabolism", "5": "Retrograde transport at the trans golgi network", "6": "Mitochondrial calcium ion transport", "7": "Intra golgi traffic", "8": "Ion channel transport", "9": "Glycosaminoglycan metabolism"} \ No newline at end of file diff --git a/msigdb_reactome/advanced/plot_0.png b/msigdb_reactome/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6b710b1276cb98acbd351bd7fa632978d235d157 --- /dev/null +++ b/msigdb_reactome/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f0ec5f96a2524d5a1d0456c01f3c6193eb4b0c69aa8484ee547a71b1857217f +size 220968 diff --git a/msigdb_reactome/advanced/plot_1.png b/msigdb_reactome/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..281a4aa52199e04a649d67a4aa042911f27e03a2 --- /dev/null +++ b/msigdb_reactome/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5a91125833ddd1466fce14ac86fde6b579bf1e1734b4420c4b160a485b975902 +size 200084 diff --git a/msigdb_reactome/advanced/plot_2.png b/msigdb_reactome/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..b140b6182c95539bbce15fe715c5aaee215bed66 --- /dev/null +++ b/msigdb_reactome/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b607dbf9e6e08d8331511e83548aeb12c527d8404b1c615a01ce3f369047ba11 +size 199748 diff --git a/msigdb_reactome/advanced/plot_3.png b/msigdb_reactome/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..4e66ebee066a0b509ebbea32c34f36a7d58b7db8 --- /dev/null +++ b/msigdb_reactome/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:748013cf708a730979e5a2c2e90b8deffa6807a1741fa3bc62e41cdfe7524af2 +size 204746 diff --git a/msigdb_reactome/advanced/plot_4.png b/msigdb_reactome/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..4eba9f588dae46b12dd07378cb3e607e7a2ee748 --- /dev/null +++ b/msigdb_reactome/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d261dc9489f00f0e43649121311df0493b416a87f0ff7ed2ba4604c63aae87bf +size 195246 diff --git a/msigdb_reactome/advanced/plot_5.png b/msigdb_reactome/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..b14d99cb3a923f12b9d3da65d3c565dca6dbff5a --- /dev/null +++ b/msigdb_reactome/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9e26572ae24973549d747cc3e28cffb7b0d3e320a0f2979792a817f65ae26a7 +size 207581 diff --git a/msigdb_reactome/advanced/plot_6.png b/msigdb_reactome/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..d6bf274deb8cd8c9eff0e4e33ec8929cef5139e2 --- /dev/null +++ b/msigdb_reactome/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00f7bf9949faa3a3ebec03e4b5d0fa6521232d1e75eb998a6f8f36f758794799 +size 197742 diff --git a/msigdb_reactome/advanced/plot_7.png b/msigdb_reactome/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..03b4f0d702ae0bd941a1d1729fa449dfd116e8f6 --- /dev/null +++ b/msigdb_reactome/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f394be771b48eb79345fd1ce41df9fb816c5793d48a7b74b42b7a0bd4e65f03 +size 194278 diff --git a/msigdb_reactome/advanced/plot_8.png b/msigdb_reactome/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..dda55768fbf604c75c63e38f92355dd57fd18230 --- /dev/null +++ b/msigdb_reactome/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b735251e998f468a5e80ddabea0f182f4003bff7dced797f8e58b39ee44bdf87 +size 201930 diff --git a/msigdb_reactome/advanced/plot_9.png b/msigdb_reactome/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..284ebc1ad3f67db408fe76e495c1b9972e115a93 --- /dev/null +++ b/msigdb_reactome/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33ccf72b5cf5907d98827a9486dce48a4a61531f2c9f88e49875835f48183716 +size 199221 diff --git a/msigdb_reactome/basic/idx2term.json b/msigdb_reactome/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b0541ec3fe22af5f19e6d99cd9e1f72b4a9f01d7 --- /dev/null +++ b/msigdb_reactome/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport of small molecules", "1": "Sphingolipid metabolism", "2": "Mitochondrial protein import", "3": "Slc mediated transmembrane transport", "4": "Glycosphingolipid metabolism", "5": "Retrograde transport at the trans golgi network", "6": "Mitochondrial calcium ion transport", "7": "Intra golgi traffic", "8": "Ion channel transport", "9": "Glycosaminoglycan metabolism", "10": "Ire1alpha activates chaperones", "11": "Cristae formation", "12": "Protein localization", "13": "Sphingolipid de novo biosynthesis", "14": "Metabolism of lipids", "15": "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "16": "Mitophagy", "17": "Class i peroxisomal membrane protein import", "18": "Processing of smdt1", "19": "Pink1 prkn mediated mitophagy", "20": "Stimuli sensing channels", "21": "Cholesterol biosynthesis", "22": "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "23": "Rhog gtpase cycle", "24": "Peptide hormone metabolism", "25": "Respiratory electron transport", "26": "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "27": "Transport of inorganic cations anions and amino acids oligopeptides", "28": "Mitochondrial biogenesis", "29": "Glycerophospholipid biosynthesis", "30": "Cargo concentration in the er", "31": "Tp53 regulates metabolic genes", "32": "N glycan trimming in the er and calnexin calreticulin cycle", "33": "Phospholipid metabolism", "34": "Rhoa gtpase cycle", "35": "Synthesis of pa", "36": "Rac2 gtpase cycle", "37": "Selective autophagy", "38": "Intra golgi and retrograde golgi to er traffic", "39": "Platelet homeostasis", "40": "Insulin processing", "41": "Rnd2 gtpase cycle", "42": "Rhod gtpase cycle", "43": "Vesicle mediated transport", "44": "Diseases of glycosylation", "45": "Unfolded protein response upr", "46": "Ion transport by p type atpases", "47": "Slc transporter disorders", "48": "Recruitment of mitotic centrosome proteins and complexes", "49": "Rnd1 gtpase cycle"} \ No newline at end of file diff --git a/msigdb_reactome/basic/plot_0.png b/msigdb_reactome/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2fe4ffbd61ae8f1ade69fa03a63682d4bcc87243 --- /dev/null +++ b/msigdb_reactome/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:feb338234da628a59677acdf398cc8fa2fa3bf7b2e17bd3758b15670d4f600e0 +size 152744 diff --git a/msigdb_reactome/basic/plot_1.png b/msigdb_reactome/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8d7261041b9317d5d657d461ed867c064f7e50ce --- /dev/null +++ b/msigdb_reactome/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:697c482867be79e9ee93b5f5610cf397bed0f3f1f6a3f9df712d4b5dfa7c4a71 +size 145910 diff --git a/msigdb_reactome/basic/plot_10.png b/msigdb_reactome/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..30c447cd1848115db9fcc3af9d3d3d9c6676546e --- /dev/null +++ b/msigdb_reactome/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5709e534d3c0a2d905b37ae870556a7a73ae083ea130971a60a42cb7f3ff76a1 +size 147023 diff --git a/msigdb_reactome/basic/plot_11.png b/msigdb_reactome/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..8ee53cb36550b72e1431392cdda89aa63836c66c --- /dev/null +++ b/msigdb_reactome/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:04fd11d28e8ce9916ec3d7d4537ad683edfd44ebb51ffcf8a42b3dac3875e89d +size 141906 diff --git a/msigdb_reactome/basic/plot_12.png b/msigdb_reactome/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..b98c02aaaa2cfaf85609e3a39a7482b519f93d5a --- /dev/null +++ b/msigdb_reactome/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:59bc7ab29521f88131821da752fcc1bed1c9ea4e97b17d6ae95807c02e05f3cb +size 140005 diff --git a/msigdb_reactome/basic/plot_13.png b/msigdb_reactome/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..3edda8826cf2f5cfd37e3d46c0625c5be0f6b129 --- /dev/null +++ b/msigdb_reactome/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9637d0677e97aa393f9306efb46ad8d7bfa9761fe54bf9282ab969bf17d94749 +size 148114 diff --git a/msigdb_reactome/basic/plot_14.png b/msigdb_reactome/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..5e12dd0cc3c542e2b49964bcf3f69a6d4f75983f --- /dev/null +++ b/msigdb_reactome/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:190c370196d53ced3d2a62fa7f719a37b1d7757e8ccaa56b6108ead28fe55ddc +size 148081 diff --git a/msigdb_reactome/basic/plot_15.png b/msigdb_reactome/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..d75bc8b70a8bda4f57a8844dc011176937476d62 --- /dev/null +++ b/msigdb_reactome/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:411ff12a51be263c9e844e2a157c564767cf0d02730163727c6a5bb076cc0929 +size 149616 diff --git a/msigdb_reactome/basic/plot_16.png b/msigdb_reactome/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..822475bd7e73c11144cb92ed32ef742d54af1c97 --- /dev/null +++ b/msigdb_reactome/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e263a54700ee7c5565856aae6a35aecdcde4f8b342cca5ae1283c8dc5b4d71d +size 135327 diff --git a/msigdb_reactome/basic/plot_17.png b/msigdb_reactome/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..e92e511b85d0f09f69c090e22b9d6c3138b32f1f --- /dev/null +++ b/msigdb_reactome/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52a0f6b2f082938f221f6f768fc6ae1b3c3a48a3186555fa918833b9597c6061 +size 145603 diff --git a/msigdb_reactome/basic/plot_18.png b/msigdb_reactome/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..0653a7e92d706310b7ac203875248613774bd7cb --- /dev/null +++ b/msigdb_reactome/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da2772b33a620f15576a97ad393f1cff44e022ddf340d7b210cb03d7a838b08a +size 137995 diff --git a/msigdb_reactome/basic/plot_19.png b/msigdb_reactome/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..8ecd775b9714fca8613690c4973fba3212673d58 --- /dev/null +++ b/msigdb_reactome/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ebfe4a97e1481fef94fee5cfd513df9bd3931b947904751af3c40f7eef3ea14e +size 143732 diff --git a/msigdb_reactome/basic/plot_2.png b/msigdb_reactome/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..838bc431bba2f0d5d031c47b0f3cdd01fef7ecd1 --- /dev/null +++ b/msigdb_reactome/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f17cf8b314a815ed664fc13b5308bf638345717eb609c88b51d2748c0461e9c +size 142306 diff --git a/msigdb_reactome/basic/plot_20.png b/msigdb_reactome/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..5566b8807d750d21947d0fae692900db79e155fe --- /dev/null +++ b/msigdb_reactome/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5e70b16b5d64bf793cf9e8c3fa9fa3d1eb97afdf3e54a336e1404b3d95d5011 +size 140054 diff --git a/msigdb_reactome/basic/plot_21.png b/msigdb_reactome/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..5b379b0b17ac0b140c59a460a4e80590d9ee123b --- /dev/null +++ b/msigdb_reactome/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2386da774c1984a3d37436d27d800b85d8abe5769200c302f6192aa2b760fd57 +size 142474 diff --git a/msigdb_reactome/basic/plot_22.png b/msigdb_reactome/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..0dd9c514d4e2a4a3304f5053cde760b56ab5b554 --- /dev/null +++ b/msigdb_reactome/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3bc59e4a3541dd50daf0785b1f9ef140ecc24769d7736dfcc71bef39a8f1307b +size 142415 diff --git a/msigdb_reactome/basic/plot_23.png b/msigdb_reactome/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..56feda05245437ff77c6cbdfb13c63f61aa2749e --- /dev/null +++ b/msigdb_reactome/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f97b0dc4a27af352988707a0401f462abbd63540e4ab264a9cf9017aaba35a5d +size 143682 diff --git a/msigdb_reactome/basic/plot_24.png b/msigdb_reactome/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..14b38e5ec41badd315db62b7986ba8398c343a18 --- /dev/null +++ b/msigdb_reactome/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6734a0718c5af7b3041b91e3883a8531d63c9b3d440ce9183ba7d9e11004fb48 +size 141846 diff --git a/msigdb_reactome/basic/plot_25.png b/msigdb_reactome/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..969a4af4b63831aa93b6bddf65501f76909f86d8 --- /dev/null +++ b/msigdb_reactome/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c48d80361cf7bd56f2f61c1cfa78d14c96aa379e2634350a3e0874ac906626d +size 145870 diff --git a/msigdb_reactome/basic/plot_26.png b/msigdb_reactome/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..1491c0ed02f4657bcd573dea045c079a9ff4d6ad --- /dev/null +++ b/msigdb_reactome/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0a179e16a736345db5d454ab9c63390a595ab555b5b7d70371194941ca9d827 +size 128174 diff --git a/msigdb_reactome/basic/plot_27.png b/msigdb_reactome/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..4671e24a47ebeb960c665532dcdead89a7ac08b7 --- /dev/null +++ b/msigdb_reactome/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:609556f74b8c255e4963ba3cf4beaa197f0865ab064991a585980755418ce064 +size 143745 diff --git a/msigdb_reactome/basic/plot_28.png b/msigdb_reactome/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..4acba3d26277ab3c8046fd4c2e496cc27032f327 --- /dev/null +++ b/msigdb_reactome/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4632dcece19200c6eb916e5ee9fd93c72d586b61b76d8c5b3280ce05d1469baa +size 146389 diff --git a/msigdb_reactome/basic/plot_29.png b/msigdb_reactome/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..8bf0ae2548dce3812b54da707b7eb4b7f834dbac --- /dev/null +++ b/msigdb_reactome/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:873559db61843fc8a4214c89cba28f91429ceb51d4a0f0fabd6edcfba422dd6a +size 133319 diff --git a/msigdb_reactome/basic/plot_3.png b/msigdb_reactome/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..32cd701ba6997d0f4b715a28eafc28d2bdf12c43 --- /dev/null +++ b/msigdb_reactome/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3b325c9d4e16376178a9bee6bb340f71fb9faa38ed8ac3c6b0519b4ac5d2aa76 +size 148307 diff --git a/msigdb_reactome/basic/plot_30.png b/msigdb_reactome/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..152483ac67857c8d544e2709c0e29c1562d5c5b2 --- /dev/null +++ b/msigdb_reactome/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2eaedf1ec92f7bb6e60392586ca4b20cf6365b85eeb753be67eeda0b9bfd88be +size 134633 diff --git a/msigdb_reactome/basic/plot_31.png b/msigdb_reactome/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..54df0dd3a80595b048aab5ef6a0cedbce9ea265b --- /dev/null +++ b/msigdb_reactome/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba3d67fd8a363dbfe0d2ce672ba6c8f04a7653588add02f42e56267e30d6b359 +size 146542 diff --git a/msigdb_reactome/basic/plot_32.png b/msigdb_reactome/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..590477087c8a8d6c61740b2920efc8e0ac39a3cd --- /dev/null +++ b/msigdb_reactome/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ed5dd9da91292ed1daeb0bbca4ef6b97437a5f91e6fe50a8713ebec0545abab +size 139499 diff --git a/msigdb_reactome/basic/plot_33.png b/msigdb_reactome/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..adb5255da74f76f6d964ef012cdaacec1e7061e1 --- /dev/null +++ b/msigdb_reactome/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:902ce26db45194ff049187746bc6d0ab1e3e83620797fee73e07867fd5b7304b +size 142627 diff --git a/msigdb_reactome/basic/plot_34.png b/msigdb_reactome/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..c9d14c2215d228df63438b8998d3f93464c6ae2a --- /dev/null +++ b/msigdb_reactome/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:819a000eaecaf46c6c06f33c8cbf37250e4ebf1e4ac2187b12242153ffe9415b +size 143705 diff --git a/msigdb_reactome/basic/plot_35.png b/msigdb_reactome/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..4882f6880d09fd17d51a136c4dc51a0a9c192b04 --- /dev/null +++ b/msigdb_reactome/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2eb5ddc5753b7a560845ac808f912a675a730645a4b196c367b28d6016e70c50 +size 134766 diff --git a/msigdb_reactome/basic/plot_36.png b/msigdb_reactome/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..1aaf57ebd7597f4ae3de4839215e3425ce9e61ca --- /dev/null +++ b/msigdb_reactome/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b933e2ce5c3395d37e7a15e930b9f14ff379756804c470a97341e6bf7265df03 +size 144405 diff --git a/msigdb_reactome/basic/plot_37.png b/msigdb_reactome/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..96b87b1aad05ab76d45b36ec36fa84734155f1af --- /dev/null +++ b/msigdb_reactome/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e18ecac60e932f06e7edbbd1d167ebad3089bee8aea21c039b994c7ff178df7 +size 139770 diff --git a/msigdb_reactome/basic/plot_38.png b/msigdb_reactome/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..299b656998320de617f07c892cb14d331b60ab92 --- /dev/null +++ b/msigdb_reactome/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:603d683840dfba9a621de14281c4f9026236019a5af91a9dcfdf9d175a8e1280 +size 149970 diff --git a/msigdb_reactome/basic/plot_39.png b/msigdb_reactome/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..52c5bd7df18ac126f879660f6d86e607d245a858 --- /dev/null +++ b/msigdb_reactome/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ab3a9d9453e0ce6db822f3c7fd92c217f290f83cf8806e3614e3b95a3037219 +size 134872 diff --git a/msigdb_reactome/basic/plot_4.png b/msigdb_reactome/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..379cccffac5caca328cc233d648689609c81f9cf --- /dev/null +++ b/msigdb_reactome/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e9c03196dcd452c2aee9222a16d0f93ffdbb61fd70efcf31e57249249ca0678 +size 146208 diff --git a/msigdb_reactome/basic/plot_40.png b/msigdb_reactome/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..4e85940e117cb49b074cb53f0c8edabec6bc32cb --- /dev/null +++ b/msigdb_reactome/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb3ca6c9e38f305219bf310b78c386b2c16bfbf71efa99f59f8614c5a551b0ff +size 121807 diff --git a/msigdb_reactome/basic/plot_41.png b/msigdb_reactome/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..bf3f9f846a8ffcc38af74e6f4490561f500a0972 --- /dev/null +++ b/msigdb_reactome/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b98f59f438850bf2a852c52e60a6335fde81ff1f17c5e9b4ae9dda1caa589cf +size 140755 diff --git a/msigdb_reactome/basic/plot_42.png b/msigdb_reactome/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..3949f53cc745dd1480da8cebabf776a8380f6eec --- /dev/null +++ b/msigdb_reactome/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:987ddcdd53ef100750b6d7221d0d6537c2eb0988e429056324c43cbf65651fa6 +size 143932 diff --git a/msigdb_reactome/basic/plot_43.png b/msigdb_reactome/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..6e76c2cdb0f9399c89f27e53b1823ec85e8a9eb5 --- /dev/null +++ b/msigdb_reactome/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f56538cc0ca8f76cf821156bc04461cbc4f70435a3857e53a952bd71b780545 +size 144091 diff --git a/msigdb_reactome/basic/plot_44.png b/msigdb_reactome/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..7b9db891d1c4c270925f5ee0d4b73d2b38a90643 --- /dev/null +++ b/msigdb_reactome/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c8fbcf62b7649d256a995947bad7ddd6fe1672a1b596727bfca70d15fb1d637 +size 138935 diff --git a/msigdb_reactome/basic/plot_45.png b/msigdb_reactome/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..2acebf21cc675f62c8f0bc39d2ad9d47f8724ae3 --- /dev/null +++ b/msigdb_reactome/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4213fdf420a429797f6ab82a6faf93818c935c1a100249b2e8b399a9b8d4284 +size 143956 diff --git a/msigdb_reactome/basic/plot_46.png b/msigdb_reactome/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..1a0708efb1efb2b649e597c9e46f6c2003f1198d --- /dev/null +++ b/msigdb_reactome/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0bfb0c8fe296645d59e293499e97c00bcc2db0598ed34cd6c727066675a362d0 +size 136390 diff --git a/msigdb_reactome/basic/plot_47.png b/msigdb_reactome/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..f2cb2a1193dd5cfe00991db034a78f3d03436c5b --- /dev/null +++ b/msigdb_reactome/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78c17bac6b7598032e8453901527be088e27933085979b31e38a58c19e414937 +size 144535 diff --git a/msigdb_reactome/basic/plot_48.png b/msigdb_reactome/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..2b838164f043c693f003d9fb8df57e600651ec59 --- /dev/null +++ b/msigdb_reactome/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a9c5691e7f3b39f29db754d9ceea7e4f3444140bb64bf8c6704f472059cdc9d +size 149334 diff --git a/msigdb_reactome/basic/plot_49.png b/msigdb_reactome/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..7a2e090e8e370236f2bdb6134e7e8022436b76ae --- /dev/null +++ b/msigdb_reactome/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3711896a1ddce13f6bf1d0b59cd8d43e0dc61bccf34c417cc587785735f2a55c +size 132733 diff --git a/msigdb_reactome/basic/plot_5.png b/msigdb_reactome/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..3c00840bdf58c802ccfe69a8c97e4a23f1c82972 --- /dev/null +++ b/msigdb_reactome/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:09c7db9f90daceacb17a7a8d7ac1407f75c297b9e21ed050896922782f3446a3 +size 148070 diff --git a/msigdb_reactome/basic/plot_6.png b/msigdb_reactome/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..cff3dda17593253b26167cd9492d4a7e39c882a0 --- /dev/null +++ b/msigdb_reactome/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:647463b649d9f2a6038a9f78c4870991f0cfb3b7cbbcf4a518cae8c0fb180c26 +size 143159 diff --git a/msigdb_reactome/basic/plot_7.png b/msigdb_reactome/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..90e4d1c521791e9a853e08e744a3f3efb047ffcc --- /dev/null +++ b/msigdb_reactome/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6e9c313b98c896352008bb25c862c13bd310707308ab49478e918dc85a5a0ec0 +size 136965 diff --git a/msigdb_reactome/basic/plot_8.png b/msigdb_reactome/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..bf598964424c7b27267582dc6d667bd74507360f --- /dev/null +++ b/msigdb_reactome/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb43502dab226228e9cce7ee9981df3529b4ddb0f360e90ceeb22150efb9f75e +size 140059 diff --git a/msigdb_reactome/basic/plot_9.png b/msigdb_reactome/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..a443298fb0c6c5e7150b30dd86837b2019f21ce6 --- /dev/null +++ b/msigdb_reactome/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a2154ae68113b0edcbdd7e1ce2f51a22b60baafa2325280522ef68a5d234a19 +size 144034 diff --git a/msigdb_reactome/consensus.joblib b/msigdb_reactome/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..213521774f19fab28738cc3105d9da22c1091cb2 --- /dev/null +++ b/msigdb_reactome/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d0e4e189c3136fe4c4c43252788c45bbb6e5a4851e5c529dff2fc03872b2d932 +size 176058 diff --git a/msigdb_reactome/df_merge.tsv b/msigdb_reactome/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9f788fb1c6ac244eed5f594c253fe2109753f44d --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,45 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport of small molecules 78 174 4.83917348450435 1.3038020118983103e-06 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 9.525749926321952e-13 0.2612966814673029 0.1545448473936569 3.1798524403343675e-08 4.707361614775529e-13 +Sphingolipid metabolism 18 28 4.522906819753988 6.099609731080591e-06 11.00242718446602 26.135922330097088 1.1708540815039898 0.1757583754913391 4.192861933829232 2.1968580551223003 2.1941615995620167 0.2567064655985949 3.4348172755789006e-10 0.0030481683180534 0.0003105660221664 2.0623686999188287e-06 4.325222546364907e-10 +Mitochondrial protein import 20 38 4.196653909518519 2.7088739765313008e-05 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 1.2374732611603888e-13 7.726764735657812e-06 1.3843081040417905e-06 1.085928935689268e-09 1.63515240194786e-13 +Slc mediated transmembrane transport 12 24 3.663890106311318 0.0002484133995646 8.672330097087379 21.910194174757283 1.4735742044813558 0.239038892478899 4.348519601656105 3.146764860695784 1.3934177975338422 0.3068823132077037 0.0010343464555712 1.0 0.6248041208228576 0.0030790050493254 0.0011775943662494 +Glycosphingolipid metabolism 10 16 3.529283833176036 0.0004166859647904 7.514563106796117 15.521844660194176 0.6340330218232789 0.1371235236408302 2.3948329397108954 1.2175929202976112 2.2116324239586063 0.2290247571497847 2.0441042613272442e-07 0.0104419310742173 0.0002651548018521 1.1213911854546629e-05 2.3596719796488026e-07 +Retrograde transport at the trans golgi network 12 24 3.411810909952771 0.0006453286150913 4.779126213592233 17.143203883495147 0.3613851487031342 0.4884664603565215 2.6268315318443034 3.9886218545053063 1.007707670827069 0.3163228122840523 0.000460508762564 1.0 0.3777229935777695 0.0304079267330467 0.000510790199304 +Mitochondrial calcium ion transport 12 18 3.327424217389284 0.0008765282631828 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 2.188616628972203e-07 1.0 0.1837383274168749 0.0135296171343662 2.470762859035699e-07 +Intra golgi traffic 12 19 3.207083115913988 0.0013408824868994 4.424757281553398 13.87135922330097 0.7636302424906817 0.4243971711811651 2.688824171738392 3.845367291797066 0.9598354803720488 0.3140361333882177 2.157746238321156e-05 1.0 1.0 0.0182997950486615 2.4396953757339905e-05 +Ion channel transport 19 34 3.132449488416534 0.0017335425359501 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 0.000129600752696 0.3219228357858488 0.5484830827387088 0.0485304500002844 3.6005403560523816e-05 +Glycosaminoglycan metabolism 9 17 3.11225187233246 0.0018566601768816 6.563106796116505 14.388349514563108 0.750167459040055 0.1742505874253542 2.387954817808654 2.3973407990867264 1.8682770414846892 0.2409021330213527 0.0059911105297108 1.0 1.0 0.0068401475593005 0.0065607705696853 +Ire1alpha activates chaperones 9 28 3.094690126189265 0.0019701861606886 6.050970873786408 24.223300970873787 0.9379365742980283 0.4047880585679882 2.6930013625985207 2.1985522104416564 1.0262193137091864 0.3353529084578252 0.0001966729178519 0.1878492321971458 0.0085749794431607 0.0006205149914719 0.0002188253858891 +Cristae formation 12 22 3.08608463968536 0.0020281108198756 8.475728155339805 19.805825242718445 0.8613288847471563 0.2756396593916832 3.7825471979528897 1.2052333490949263 1.5890526548766304 0.3070386069824295 1.790635184575399e-08 0.0070670490819082 0.0274603336438859 0.0004179970223822 2.075161383728372e-08 +Protein localization 36 82 3.038364040111478 0.0023786641290504 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 1.0790935416419644e-13 4.004277303477053e-06 8.408639046500143e-06 8.548982321199652e-09 1.5985351193565313e-13 +Sphingolipid de novo biosynthesis 7 12 3.0212810295702357 0.0025170762368602 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.0003471406336639 0.1280604643503683 0.2445730022705269 0.0322769586697076 0.000378511976274 +Metabolism of lipids 70 211 2.980221760465167 0.0028803977769151 47.21601941747573 182.9902912621359 0.7669400545274999 0.4573741022352977 16.76057659641467 20.451455734561765 1.5920609507025254 0.4091924181498379 4.2743980188584566e-10 0.0891522955474903 0.0550117917040987 3.879117534999815e-05 7.430012293108445e-10 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 15 21 2.889588862136 0.0038574596519975 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 0.0049346831596089 1.0 0.1009015630926116 0.1537817902530961 0.005371579016814 +Mitophagy 5 13 2.689133689460735 0.0071637722761186 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0007580426681942 0.0056070915236824 0.0015052123544451 0.0024379570615939 0.0008169542553505 +Class i peroxisomal membrane protein import 7 12 2.645015844291536 0.0081687091993347 4.300970873786408 9.604368932038836 1.1426576411245968 0.2560233101944223 2.515331441636984 1.9424437465598188 1.2133199793435778 0.2911424942178205 0.0001875150216886 0.0858288536093336 0.1677870330809631 0.0009779431698101 0.0002026911007435 +Processing of smdt1 8 13 2.631173604258687 0.008509055764017 4.975728155339806 11.155339805825244 0.3833102568885913 0.3649000478471426 2.609615007852169 1.2287595888742628 1.3301610577177632 0.3259664414506655 0.0006988566317415 1.0 1.0 1.0 0.000745702459351 +Pink1 prkn mediated mitophagy 5 10 2.6239828790796467 0.0086908153693978 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 9.285534997667568e-05 0.0028214739728005 0.0005309775927247 0.00062382482254 0.0001004910149917 +Stimuli sensing channels 6 12 2.599124872610112 0.0093461767682192 3.075242718446602 8.648058252427184 0.6737384899082146 0.3285895756392196 1.7754169999219978 1.9694070657894505 1.2463928142905627 0.307032431313504 0.0088126864345141 0.1644315705571846 0.3076603852203092 0.063688713570506 0.0020949039384023 +Metabolism of porphyrins 4 10 2.592103165757273 0.009539116134295 2.766990291262136 9.186893203883496 1.2638611374915407 0.2204767139400954 1.3861582272503026 1.170645435718008 1.0950295956895657 0.2541910601955712 0.0009513571658216 0.0028214739728005 0.0005309775927247 3.906142953800441e-05 0.0010145405611514 +Transport of vitamins nucleosides and related molecules 4 8 2.564323421046274 0.0103377165781572 3.2985436893203883 7.703883495145631 0.5884630304197642 0.3368828823659784 1.766928610360549 0.9135891377639136 1.2550983698791685 0.3076045725047946 0.0026687375683324 1.0 1.0 0.0135296171343662 0.0028394369313259 +Cholesterol biosynthesis 9 17 2.5497658298983974 0.0107795296191692 5.878640776699029 16.75 1.3996798653689082 0.2350718901934974 2.503362805703168 1.8986773628384943 1.0886216368414 0.270950573691616 8.554510128591262e-07 1.0 0.2070995190727305 0.0002335266734922 9.63883996768495e-07 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 29 67 2.4073195846517725 0.016070100189468 20.8373786407767 62.38106796116505 0.8350130317954786 0.3584533980641267 8.974357262450994 5.887120286458052 1.9056004199022172 0.3784220720284639 1.1894210096242878e-07 0.0002025840945074 1.4782009248559458e-05 2.3111698587352784e-05 1.511890111597015e-07 +Rhog gtpase cycle 14 38 2.405769168909572 0.0161384582579853 9.8373786407767 35.66504854368932 0.6614029400837433 0.4973720188279035 4.308521802053122 2.993429981792782 0.9950331841901028 0.3588671909523165 0.0530236274766455 1.0 0.497470817800254 0.516414990920093 0.0564249445308771 +Peptide hormone metabolism 10 16 2.3962590416259104 0.0165633798982636 4.021844660194175 14.021844660194176 0.5560275504881529 0.5205961274891826 2.4979619838894513 2.4069092486442756 0.8833525414026219 0.3339695456705046 0.3405496111808982 0.1839914155878272 0.3404254693467198 0.2797556636969028 0.3487517012854798 +Respiratory electron transport 27 56 2.370984596446509 0.01774077042844 17.473300970873787 52.5752427184466 0.7619430018929745 0.3962973483509951 7.757662405441163 5.39117119769307 1.7039672197087123 0.3858226471737118 2.244645950329876e-05 0.011820001819681 0.0004105222060924 0.0007457783870921 2.671732266324261e-05 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 5 11 2.334646856034083 0.0195618766401486 4.016990291262136 10.99757281553398 1.1239772251284714 0.2752182956921286 1.9514004604865949 1.181365809872934 1.0815649178051203 0.2865915409883788 0.0001875150216886 0.0035263772514821 0.014058804472369 0.0762921742488627 0.0002026911007435 +Transport of inorganic cations anions and amino acids oligopeptides 8 12 2.321088383286526 0.0202820742217222 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.0580802807538155 1.0 0.3467918934582977 0.0901467992310857 0.0610180463767549 +Mitochondrial biogenesis 15 40 2.279438035272789 0.0226410394981477 10.572815533980584 33.521844660194176 0.7125383902440768 0.3998427377933914 4.798567629623383 2.9315837025395943 1.2191838320541302 0.3355715376706868 0.0006976264490795 0.0605318649589048 0.0483217377147592 0.0169357854376417 0.0007906234883712 +Glycerophospholipid biosynthesis 15 34 2.245253120759469 0.024751887669103 9.439320388349516 29.58009708737864 1.1800609247564997 0.3081196451067344 4.809346434845489 4.094857299253986 1.3402414818469337 0.3224557628717913 0.0025951555962472 1.0 1.0 0.0574018644712506 0.002896721501077 +Er quality control compartment erqc 3 5 2.2003078953874 0.0277850574972049 1.0606796116504855 2.9635922330097086 0.5833647682671571 0.4456356260955993 0.95210932118493 1.2251945392339945 1.1415139733942834 0.3344847203664676 0.0093478027703867 1.0 1.0 0.0087554356838108 0.0098193480789534 +Cargo concentration in the er 7 17 2.1559446607175663 0.031087986572601 4.813106796116505 14.480582524271844 0.5034715777808771 0.4707340910089172 2.4168749497181627 1.7521447745979526 1.0073939692365603 0.3173017432503084 0.0040771188388817 1.0 1.0 0.4314443861210575 0.0043329575683166 +Tp53 regulates metabolic genes 14 39 2.1542827778520093 0.0312180026337545 9.567961165048544 35.47572815533981 0.101655991626129 0.675386172281155 4.509186170565808 3.1224046626849615 0.8223942836099251 0.3288916000544298 0.1076439852368788 1.0 0.5571911012951047 0.6078620891205404 0.11375295949697 +Heparan sulfate heparin hs gag metabolism 4 7 2.132761359498629 0.0329443075367803 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.0650574840344539 1.0 1.0 0.0415700360883472 0.0678374957909117 +Gpcr ligand binding 3 9 2.1230286655903554 0.0337514498348967 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.177542977127603 1.0 0.3593428278464597 0.3067990234802971 0.1838658218206393 +N glycan trimming in the er and calnexin calreticulin cycle 5 17 2.04515546757344 0.040839533275518 4.878640776699029 14.699029126213592 0.108355189317792 0.5779465857553798 2.939491749392236 1.3189062212723417 0.9052506944453566 0.3169163043543442 0.0171326261044573 1.0 1.0 0.0070923684446229 0.0039537733222705 +Formation of atp by chemiosmotic coupling 4 11 2.0421081203665805 0.0411408075752732 3.5898058252427183 9.805825242718448 0.4783111855246443 0.2899716869602585 2.2195497140568734 0.9063771094889388 1.382334358445268 0.2713732710506487 0.0003469428870386 0.0019049706229129 0.0077184558590264 0.0041946485896371 0.0003706302782608 +Keratan sulfate keratin metabolism 4 6 2.021959872662796 0.0431804975329876 3.1359223300970873 5.439320388349515 0.1148000450757159 0.1857420338858874 1.294488268568909 0.7592200419566036 1.8452752770630356 0.2520366769461069 0.0075518132359909 1.0 1.0 0.062605312422627 0.0079370796506279 +Transport of bile salts and organic acids metal ions and amine compounds 4 5 1.9823185246780244 0.047443601990641 1.8349514563106797 3.995145631067961 1.0286208624357371 0.2748571167414633 1.258733277411433 1.3329199016551914 1.161382969627279 0.2758406238802445 0.0650574840344539 1.0 1.0 0.0415700360883472 0.0678374957909117 +Phospholipid metabolism 21 51 1.976284763916192 0.0481225342411235 12.859223300970871 45.932038834951456 1.017004520648936 0.3949296504793965 6.241466981115118 7.362344677079641 1.3242274243570669 0.3709328103546776 0.0078859028203281 1.0 1.0 0.3271865843905714 0.0089298824095212 +Peptide ligand binding receptors 3 7 1.9736567498953252 0.0484207861470999 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0075518132359909 1.0 0.1515272625734178 0.062605312422627 0.0079370796506279 +Class a 1 rhodopsin like receptors 3 7 1.9736567498953252 0.0484207861470999 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0163221099726736 1.0 0.1837383274168749 0.090818300458346 0.0171177319456962 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6130c82094059797ba4d8e1816ddf6eaa7b66316 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 1419, + "title": "Average number of proteins per term", + "value": 20.701198026779423 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b75b68d4b04d7510d62f323a8f4e130ceca925f3 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3868bb6bc4ab5d6a8d30575125d1d694c88bbb35 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,372 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport of small molecules 0.4894450622566288 4.83917348450435 1.3038020118983103e-06 0.0018483858878251 0.0009250475274425 174 P36543,P09601,O75027,Q96TA2,P30519,Q9C0H2,Q9UL46,Q99623,P28072,Q8WWC4,Q9UBX3,Q9UJZ1,P21796,P45880,Q13438,Q70HW3,P08183,Q9UBV2,P33527,P35613,P33897,Q9H2J7,Q8N4V1,P53985,P28070,Q9NP58,Q8TAD4,O00400,O15439,P05023,Q8TB61,Q9BUN8,Q8WTV0,P27105,Q96QD8,Q9Y277,P02786,P49721,Q9HD20,Q96PU5,P12235,Q9GZP9,Q04656,Q15904,P40855,P51797,Q9UEY8,P61916,Q9NUT2,Q9Y6M7,Q86WC4,P55011,P51798,Q8IYU8,P12236,P05026,O94905,O15118,O95202,Q9NW15,Q9H300,P30825,Q93050,P23634,Q9BPX6,P07237,Q9UNS2,Q15043,P20020,P05141,P16615,P61289,Q9Y487,O00231,Q10713,Q9NWR8,P51790,Q99758 78 +Sphingolipid metabolism 0.778323970664038 4.522906819753988 6.099609731080591e-06 0.00861802270494 0.0021638365521011 28 P27544,Q06136,Q96G23,P51648,P17900,O95470,Q9NZJ7,P04062,Q13510,Q16739,Q16880,Q8N5B7,P06865,P06280,O15269,P07602,P16278,P10619 18 +Mitochondrial protein import 0.6683067833810932 4.196653909518519 2.7088739765313008e-05 0.0377100230216924 0.0076877843453961 38 Q15388,O60830,Q8N4H5,Q9NS69,Q99595,Q9Y5J6,Q96B49,Q13505,Q9Y584,P12236,Q9Y5J9,O14925,Q9Y5L4,O43615,P06576,O75746,Q9NX63,P21796,O60220,P12235 20 +Slc mediated transmembrane transport 0.6912687841102199 3.663890106311318 0.0002484133995646 0.2971012364868746 0.0397943602326182 24 Q9H2J7,Q8TB61,P30825,P12236,Q15043,Q9Y6M7,Q70HW3,Q9UBX3,Q8TAD4,O00400,P35613,P12235 12 +Glycosphingolipid metabolism 0.7905387727401266 3.5292838331760357 0.0004166859647904 0.4464485663512367 0.045482875695209 16 P17900,Q9NZJ7,P04062,Q13510,Q16880,P06865,P06280,P07602,P16278,P10619 10 +Retrograde transport at the trans golgi network 0.6565146486023445 3.411810909952771 0.0006453286150913 0.5998904532820762 0.0610480869876434 24 Q8WTW3,O43493,Q8N1B4,P53365,O43752,O60499,Q96CN9,P40616,Q8N2H4,Q9UP83,Q7Z6M1,Q9UID3 12 +Mitochondrial calcium ion transport 0.7296327578703216 3.3274242173892836 0.0008765282631828 0.7118687099019696 0.0717934137832823 18 P45880,Q10713,Q99623,Q8IYU8,Q9NWR8,Q8WWC4,P21796,Q96TA2,Q9BPX6,O95202,Q9Y277,Q9H300 12 +Intra golgi traffic 0.6986369625889982 3.2070831159139876 0.0013408824868994 0.851026828628977 0.0864869204050147 19 Q8WTW3,O95249,O00461,O43752,O14653,Q15643,Q8TBA6,O15498,O60476,Q9UP83,O95721,Q13190 12 +Ion channel transport 0.5665875645656915 3.132449488416534 0.0017335425359501 0.9147384334295712 0.1069520373266636 34 P36543,Q93050,P23634,Q9C0H2,Q86WC4,P05023,P51798,P20020,P05026,P27105,Q9HD20,P16615,Q96PU5,Q9NW15,Q9Y487,Q04656,P51790,Q15904,P51797 19 +Glycosaminoglycan metabolism 0.7065516637527823 3.11225187233246 0.0018566601768816 0.9284278753765955 0.1097750329581297 17 P08236,Q8TB61,Q8NCH0,P54802,O43505,P06865,Q7LGA3,P15586,P16278 9 +Ire1alpha activates chaperones 0.5882313472570485 3.094690126189265 0.0019701861606886 0.9390957185408292 0.1106880482078282 28 P43307,O14653,Q9Y5M8,O95070,Q86TM6,O43731,O76024,Q9NWM8,O14773 9 +Cristae formation 0.6414740758758622 3.08608463968536 0.0020281108198756 0.9439107745375402 0.1106880482078282 22 Q16891,P56385,Q13505,O75964,Q9NX63,Q6UXV4,P00846,Q9BUR5,Q5XKP0,P06576,Q9NVH1,P24539 12 +Protein localization 0.549812895402838 3.038364040111478 0.0023786641290504 0.965930242258575 0.1116165993782722 82 Q15388,P33897,O75381,O60830,Q8N4H5,P09601,Q9NS69,Q99595,P05067,Q9Y5J6,Q96B49,P51648,Q13505,Q9Y584,O43808,P12236,P46379,Q9Y5J9,Q9NR77,O14925,Q9Y5L4,O43615,P06576,O75746,P50402,Q9NX63,P21796,O60220,Q9Y512,P12235,Q13190,Q10713,Q9Y3D6,Q15067,Q9BY49,P40855 36 +Sphingolipid de novo biosynthesis 0.7859682442326668 3.0212810295702353 0.0025170762368602 0.9720191210665212 0.1116165993782722 12 P27544,Q06136,P51648,Q96G23,O95470,Q8N5B7,O15269 7 +Metabolism of lipids 0.3474737379569108 2.980221760465167 0.0028803977769151 0.9833139506356812 0.1202142483953717 211 P23786,Q8NAN2,P33897,Q96G23,Q06136,Q9NZJ7,Q8N2A8,Q9H7Z7,P50897,Q9UMR5,Q16880,Q9NZC3,Q14849,Q8N5B7,Q9HBU6,P06280,Q15392,P16278,P37268,Q9H2C2,P38435,Q9P035,P51648,Q9NPH0,P17900,O95470,Q53H12,P04062,Q8NF37,O43808,Q13510,Q14534,Q16739,P06865,Q9NQZ5,P07602,Q9UKU0,Q99538,Q8IV08,P27544,Q15165,Q16836,O75845,Q92604,Q9HCL2,P04035,Q15125,Q9BTU6,P50416,Q9UG56,O75448,Q96RS0,Q9NP80,Q15800,P10619,Q96N66,Q16850,O14735,Q8NCC3,Q10713,Q53GQ0,Q8TBX8,P30536,Q15067,Q9BY49,Q14739,Q9NRA0,P33527,O15269,O95772 70 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6272018795801645 2.889588862136 0.0038574596519975 0.9958486422564272 0.1494755095949381 21 O43493,P07237,Q86UP2,Q5JRA6,Q9BTY2,Q07065,Q02818,O76024,P05067,Q06481,Q8NBJ4,Q13217,O43852,P14314,Q08431 15 +Mitophagy 0.7011116476296663 2.689133689460735 0.0071637722761186 0.9999629031676732 0.1840795651517574 13 Q15388,Q96B49,Q8N4H5,Q9NS69,P21796 5 +Class i peroxisomal membrane protein import 0.7177380261168036 2.6450158442915357 0.0081687091993347 0.9999911845187386 0.1840795651517574 12 P33897,O75381,P51648,Q9Y3D6,O43808,Q9NR77,P40855 7 +Processing of smdt1 0.691227396484804 2.631173604258687 0.008509055764017 0.9999945832473895 0.1840795651517574 13 Q10713,Q99623,Q8IYU8,Q9NWR8,Q8WWC4,Q9H300,Q96TA2,Q9BPX6 8 +Pink1 prkn mediated mitophagy 0.775471101061413 2.6239828790796467 0.0086908153693978 0.9999958240482496 0.1840795651517574 10 Q15388,Q96B49,Q8N4H5,Q9NS69,P21796 5 +Stimuli sensing channels 0.709620023086499 2.599124872610112 0.0093461767682192 0.999998366179248 0.1840795651517574 12 Q96PU5,Q9NW15,P27105,P51797,Q86WC4,Q9C0H2 6 +Metabolism of porphyrins 0.7692791876700767 2.592103165757273 0.009539116134295 0.9999987607201196 0.1840795651517574 10 P22830,P09601,Q7KZN9,P30519 4 +Transport of vitamins nucleosides and related molecules 0.7821408333540092 2.564323421046274 0.0103377165781572 0.999999605469579 0.1880669208257077 8 Q8TB61,O00400,P12236,P12235 4 +Cholesterol biosynthesis 0.6197495659230717 2.5497658298983974 0.0107795296191692 0.9999997906362124 0.1912019066200151 17 Q9H2C2,Q16850,O75845,Q14534,P04035,Q15125,Q14739,Q15800,Q15392 9 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4904774923098671 2.4073195846517725 0.016070100189468 0.9999999998962136 0.2348425722540394 67 Q9UDW1,O75880,Q86Y39,Q9Y6N1,O14949,P00846,O43676,Q8N8Q8,O95139,P56385,O43819,O14548,P15954,O75964,P00403,P21912,Q16134,Q9NPL8,P06576,Q96I36,P03886,Q7L592,P13073,Q9Y6M9,P51970,O96000,P20674,Q9P0J0,P24539 29 +Rhog gtpase cycle 0.4700266040702965 2.405769168909572 0.0161384582579853 0.9999999999059574 0.2348425722540394 38 P42166,P02786,O15173,Q86UP2,P50402,Q8TAA9,Q86XL3,P42167,Q14185,O15498,Q14739,P49257,O95202,Q13190 14 +Peptide hormone metabolism 0.6080910944266121 2.3962590416259104 0.0165633798982636 0.9999999999490544 0.2348425722540394 16 P61009,Q9UPT5,Q15005,P67812,O75787,Q96A65,P33176,Q96KP1,Q8TAD4,Q96HE7 10 +Respiratory electron transport 0.4823169039517079 2.370984596446509 0.01774077042844 0.999999999990692 0.2372973298091365 56 Q9UDW1,O75880,Q86Y39,Q9Y6N1,O14949,O43676,Q8N8Q8,O95139,O43819,O95168,O14548,P15954,P00403,P21912,Q16134,Q9NPL8,Q8N183,Q96I36,P03886,Q7L592,P13073,Q9Y6M9,P51970,O96000,P20674,Q9P0J0,P22695 27 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.69227756606111 2.334646856034083 0.0195618766401486 0.9999999999993312 0.2500748013727109 11 P51648,P50402,P09601,P46379,P05067 5 +Transport of inorganic cations anions and amino acids oligopeptides 0.6613345195420433 2.321088383286526 0.0202820742217222 0.9999999999997644 0.2506425876472353 12 Q9H2J7,P30825,Q70HW3,Q9Y6M7,P04920,Q9UBX3,Q96QD8,P55011 8 +Mitochondrial biogenesis 0.4596576236394121 2.279438035272789 0.0226410394981477 0.9999999999999925 0.2612002849420463 40 Q16891,P54619,Q13505,P56385,O75964,Q9NX63,P24539,Q6UXV4,P00846,Q9BUR5,Q96RS0,Q5XKP0,P06576,Q9NVH1,Q9Y512 15 +Glycerophospholipid biosynthesis 0.469361274273894 2.2452531207594695 0.024751887669103 0.9999999999999996 0.2621114074810244 34 Q96N66,Q9NQZ5,O14735,Q9NPH0,Q8NCC3,Q53H12,Q92604,Q8NF37,Q8N2A8,Q9HCL2,Q9UG56,Q9NP80,Q9HBU6,Q8NAN2,Q8IV08 15 +Er quality control compartment erqc 0.8673877536428558 2.2003078953874 0.0277850574972049 1.0 0.269570028993578 5 Q13438,Q9GZP9,Q9UBV2 3 +Cargo concentration in the er 0.5621409862077258 2.1559446607175663 0.031087986572601 1.0 0.2803692768183396 17 Q96PC5,Q5JRA6,O14653,P49755,Q15363,P49257,Q13190 7 +Tp53 regulates metabolic genes 0.4461638644371921 2.1542827778520093 0.0312180026337545 1.0 0.2803692768183396 39 P54619,O75880,Q9Y6N1,O14548,P15954,P20674,Q96I36,Q7LG56,P00403,P13073,Q8N8Q8,Q9NQ88,P42345,P62258 14 +Heme degradation 0.9112615056153298 2.1439017987523425 0.0320407560511699 1.0 0.2824224058502035 4 P30519,P09601 2 +Heparan sulfate heparin hs gag metabolism 0.7371236074956522 2.132761359498629 0.0329443075367803 1.0 0.2867973766545479 7 P08236,P16278,P54802,Q7LGA3 4 +Gpcr ligand binding 0.6842616791383118 2.1230286655903554 0.0337514498348967 1.0 0.2920323616812103 9 P42892,Q9NZJ7,P07602 3 +N glycan trimming in the er and calnexin calreticulin cycle 0.5463590916615573 2.04515546757344 0.040839533275518 1.0 0.3273503600889681 17 Q9GZP9,Q13438,Q9BUN8,Q86TM6,Q9UBV2 5 +Formation of atp by chemiosmotic coupling 0.6405074836300857 2.0421081203665805 0.0411408075752732 1.0 0.3273503600889681 11 O75964,P00846,P56385,P24539 4 +Keratan sulfate keratin metabolism 0.7733430154427198 2.021959872662796 0.0431804975329876 1.0 0.3366655274687337 6 O43505,P06865,P15586,P16278 4 +Transport of bile salts and organic acids metal ions and amine compounds 0.8168735891647733 1.9823185246780244 0.047443601990641 1.0 0.358098251195317 5 Q8TAD4,P35613,Q15043,Q9H2J7 4 +Phospholipid metabolism 0.4408477849251123 1.9762847639161916 0.0481225342411235 1.0 0.3597334845169366 51 Q8N2A8,Q9NZC3,Q9HBU6,Q9NPH0,Q53H12,Q8NF37,Q9NQZ5,Q8IV08,Q9NTJ5,Q92604,Q9HCL2,Q9BTU6,Q9UG56,Q9NP80,Q96N66,Q10713,Q8NCC3,O14735,Q8TBX8,Q9NUQ2,Q8NAN2 21 +Peptide ligand binding receptors 0.7051984640304239 1.9736567498953257 0.0484207861470999 1.0 0.3597334845169366 7 P42892,Q9NZJ7,P07602 3 +Class a 1 rhodopsin like receptors 0.7051984640304239 1.9736567498953257 0.0484207861470999 1.0 0.3597334845169366 7 P42892,Q9NZJ7,P07602 3 +Mucopolysaccharidoses 0.8648801128349926 1.9524741438724185 0.0508819378112272 1.0 0.3702639474570848 4 P54802,P15586,P16278 3 +Rhoa gtpase cycle 0.4392888617911126 1.9348994818961651 0.0530026317992624 1.0 0.3809198983271909 54 Q8WVM8,Q96CS3,P30519,P51572,Q14155,P42166,P27105,Q07021,O75955,Q8N5V2,P02786,O15173,Q8NBN3,P42167,O15498,P49257,Q13190,Q86UP2,Q96HY6,Q8TAA9,Q15904,Q14739,Q86VI3 23 +E2f mediated regulation of dna replication 0.5932107692197137 1.9139973180342509 0.055620498438506 1.0 0.3928545393682215 12 Q9Y619,P30154 2 +Vitamin d calciferol metabolism 0.8004837942615902 1.910579280787965 0.0560586690819318 1.0 0.3928545393682215 5 P04062,P38435,Q99538 3 +Synthesis of pa 0.5896650213170975 1.89234654243157 0.0584448235532999 1.0 0.3949200220101553 12 O15228,Q9NPH0,Q9HCL2,Q8N2A8,Q8NF37,Q9NUQ2,Q8NAN2 7 +Rac2 gtpase cycle 0.4288309577761354 1.8823278682574056 0.0597915129312331 1.0 0.4010923247699788 35 P42166,P02786,O15173,Q13505,P50402,Q8TAA9,Q86XL3,P42167,Q14185,Q14739,Q6IAA8,P49257,Q9Y512 13 +O linked glycosylation of mucins 0.8473571700335039 1.8792801730023376 0.0602062474813287 1.0 0.4010923247699788 4 O43505,Q8N4A0 2 +O linked glycosylation 0.8473571700335039 1.8792801730023376 0.0602062474813287 1.0 0.4010923247699788 4 O43505,Q8N4A0 2 +Cobalamin cbl vitamin b12 transport and metabolism 0.7920641577065218 1.8735411875225856 0.0609936907390233 1.0 0.404439472704085 5 P33527 1 +Selective autophagy 0.4209704773516557 1.8705351593542805 0.0614095392634126 1.0 0.4053029591385234 37 Q96B49,Q8N4H5,Q9NS69,P21796,P08670 5 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6820249707092978 1.8565514467259576 0.0633749971553718 1.0 0.4102205000149295 7 P30154 1 +Platelet calcium homeostasis 0.7871104392497579 1.851692418520941 0.0640700033190229 1.0 0.4113816050212376 5 Q13586,P23634,P20020 3 +Diseases associated with n glycosylation of proteins 0.6803772646585191 1.8481747885075948 0.0645770613606981 1.0 0.4127695949136519 7 Q9H3H5,Q9BT22,P15291,Q96AA3 4 +Intra golgi and retrograde golgi to er traffic 0.4295048412367133 1.841970930055944 0.0654794021675633 1.0 0.4166604111021181 109 Q8N1B4,Q8TD16,P24390,O14653,Q9UJW0,Q15363,O95721,Q16706,O15260,Q9H0U4,P62820,Q8TBA6,Q96CN9,O60499,Q9P2W9,Q8N2H4,Q9UID3,P53365,O95249,Q15643,P49755,Q12981,P11717,O15498,O60476,O43731,Q9UP83,Q7Z6M1,Q13190,Q8WTW3,O43493,O00461,O43752,Q10472,O75935,P40616 36 +Pre notch processing in golgi 0.8375176304654564 1.837981333020159 0.066065156022383 1.0 0.4185109660525069 4 Q15363,P16615,Q9UBV2 3 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7814360318925024 1.8266136968099695 0.0677578725262526 1.0 0.425435491658197 5 P12236,P12235 2 +Mastl facilitates mitotic progression 0.7802796359659891 1.8214962227884013 0.0685314603309688 1.0 0.4274588023228808 5 P30154 1 +Calnexin calreticulin cycle 0.6221969369513022 1.7997285958052558 0.0719035035031845 1.0 0.443613354221821 10 Q13438,Q9GZP9,Q86TM6,Q9UBV2 4 +Diseases of carbohydrate metabolism 0.6211586262801794 1.7939024640712942 0.072828738100038 1.0 0.4442488158018661 10 P10253,P54802,P15586,P16278 4 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6688836951039481 1.7895636831290087 0.0735240811885624 1.0 0.4442488158018661 7 P01889,Q5KU26,P10321,P04439 4 +Endosomal vacuolar pathway 0.8248236953455651 1.784499145724112 0.0743425934968569 1.0 0.4442488158018661 4 P10321,P04439,Q9UIQ6 3 +Platelet homeostasis 0.5706930268549358 1.7757687087339538 0.0757710472398804 1.0 0.4475463634149609 12 P30153,Q13586,P20020,P30154,P23634 5 +Keratan sulfate degradation 0.8176626704346766 1.7542310050096028 0.0793909325478385 1.0 0.4543608888717927 4 P15586,P16278 2 +Insulin processing 0.6079968568514539 1.7197948345480307 0.0854697418996184 1.0 0.4774864714785769 10 Q9UPT5,Q96A65,P33176,Q96KP1,Q8TAD4,Q96HE7 6 +Rnd2 gtpase cycle 0.4938252298520945 1.709693617401111 0.0873225436303057 1.0 0.4840261305132964 18 P02786,P51648,Q8TAA9,Q15058,Q07065,P38159 6 +Creb phosphorylation 0.9461516774739218 1.6813647420539932 0.0926920895687217 1.0 0.5001676646357223 2 Q15418 1 +Rhod gtpase cycle 0.4200418334807274 1.6618712117173176 0.0965386000114507 1.0 0.5150443129045551 30 P42166,O15173,Q9UEY8,P50402,Q8TAA9,P42167,Q9Y6M7,P20700,Q14739,Q5JTV8,Q86YQ8,P49257 12 +Integrin cell surface interactions 0.6940472837944676 1.649610267109745 0.0990226737097892 1.0 0.5223538066698548 6 Q08722,P35613 2 +Diseases associated with glycosaminoglycan metabolism 0.69103697551297 1.6352402621477602 0.1019986909899242 1.0 0.5321181710099355 6 P15291,P07686,Q8NCH0,P06865 4 +Vesicle mediated transport 0.3020093166924387 1.601662014697455 0.1092303692526086 1.0 0.5344041028866902 285 Q96D71,P24390,P11233,Q5VZE5,Q9UQN3,O75976,P55327,Q9BXS5,Q14677,P09496,O15020,Q96RU3,Q9UBW8,Q96CN9,Q9P2W9,P42566,Q9Y5X3,Q9Y4I1,Q9UNF0,P53680,O15498,P51151,O43731,P49257,Q8WTW3,O43493,Q12846,O00461,O43752,Q5JRA6,P40616,Q14108,Q96PC5,P54619,P61026,Q12907,Q13637,Q9BRG1,Q16706,Q9H0U4,P98164,P62820,Q07954,O60499,Q96A65,Q8WTV0,Q8N2H4,P02786,O95295,O95249,Q92905,P11717,O60476,Q14203,P61020,Q10472,P78537,Q9Y3E7,O14964,P15586,P62258,Q8N1B4,P50570,Q5KU26,Q9UJW0,Q14789,Q01082,Q15363,P05067,Q9H9Q2,Q13813,O15260,P07900,Q9UPT5,Q9UIQ6,Q9UID3,Q12981,P61923,Q7Z6M1,Q13561,Q99627,P14625,Q96KP1,Q6NUQ1,P61163,Q8TD16,O14653,Q10471,Q8WVM8,P86790,Q92783,Q9BT78,O95721,Q96JB2,Q9Y6Y8,Q8N6H7,Q9UNS2,Q8TBA6,Q92734,Q07157,P33176,P61106,P53365,P52732,O60749,Q15643,P49755,Q9UP83,Q9H0H5,Q13190,Q8WUX9,O75935,Q92538,P35606,P83436,Q9NQT8 116 +Diseases of glycosylation 0.4585998422624651 1.6005562596667076 0.1094752367307825 1.0 0.5344041028866902 21 Q8NCH0,Q9BT22,O43505,P06865,P16278,P10619 6 +Post translational modification synthesis of gpi anchored proteins 0.5866942556405065 1.5856336865347431 0.1128224299917435 1.0 0.5405326067835067 9 O43292,Q9H490,Q5H8A4 3 +Abc transporters in lipid homeostasis 0.7260251250328853 1.579056831884181 0.1143230220149971 1.0 0.5437296073983412 5 P33897,P40855 2 +Unfolded protein response upr 0.3965892151210654 1.5766817759823015 0.1148687657311209 1.0 0.5437296073983412 44 P43307,Q9Y5M8,O95070,Q86TM6,O43731,O76024,Q9NWM8,O14773 8 +Ion transport by p type atpases 0.5373105672431879 1.567859224859377 0.1169139895479265 1.0 0.5497638934115773 12 Q9HD20,P16615,Q04656,P20020,P23634,P05023 6 +Slc transporter disorders 0.4023772559368554 1.5602549555435865 0.1186996434554481 1.0 0.5497638934115773 33 Q8NFH5,Q7Z3B4,Q8TEM1,P53985,Q8N1F7,Q9BTX1,O15504,O00400,P35613,Q8NFH4 10 +Recruitment of mitotic centrosome proteins and complexes 0.3898965704398644 1.5540140237625852 0.1201810715408375 1.0 0.5497638934115773 40 Q15154,P30153,P07900,Q9H6D7,P61163,Q13561,O75935,Q9BSJ2,Q96CS2,P41208,O94927,P53350,P62258,Q14203,O95684,Q9UGJ1 16 +Rnd1 gtpase cycle 0.4995831832415961 1.546110076059157 0.1220779857457983 1.0 0.5516836362206619 14 P51648,Q8TAA9,Q15058,P38159,O75976 5 +Response to elevated platelet cytosolic ca2 0.3882794440612506 1.5300501428160442 0.1260043177744745 1.0 0.559226530526505 37 Q8NBM8,O43707,Q08380,Q8NBX0,Q12846,P13473,Q9NZJ7,Q96JJ7,Q6UXV4,O43852,Q9NUQ9,P05067,Q06481,O94919,P07602 15 +Miscellaneous transport and binding events 0.5858273646179202 1.528547198663427 0.1263767342526376 1.0 0.559226530526505 8 Q8N4V1,Q9UNS2,Q9UEY8 3 +Chondroitin sulfate dermatan sulfate metabolism 0.7636422326189611 1.5239001368330825 0.1275336592915863 1.0 0.5602794505720154 4 Q8NCH0 1 +Synthesis of very long chain fatty acyl coas 0.5830756761339022 1.5133131605582015 0.1302001313252665 1.0 0.5662508737958469 8 Q9P035,Q53GQ0,Q9UKU0 3 +Depolymerisation of the nuclear lamina 0.5501467498147705 1.51093133376865 0.1308059466149802 1.0 0.5662508737958469 11 P02545,P20700,P42167,P50402 4 +Membrane trafficking 0.296390624375045 1.5102820912971011 0.1309714594268214 1.0 0.5662508737958469 277 Q96D71,P24390,P11233,Q5VZE5,Q9UQN3,O75976,P55327,Q9BXS5,Q14677,P09496,O15020,Q96RU3,Q9UBW8,Q96CN9,Q9P2W9,P42566,Q9Y5X3,Q9Y4I1,Q9UNF0,P53680,O15498,P51151,O43731,P49257,Q8WTW3,O43493,Q12846,O00461,O43752,Q5JRA6,P40616,Q14108,Q96PC5,P54619,P61026,Q12907,Q13637,Q9BRG1,Q16706,Q9H0U4,P98164,P62820,O60499,Q96A65,Q8N2H4,P02786,O95295,O95249,Q92905,P11717,O60476,Q14203,P61020,Q10472,P78537,Q9Y3E7,O14964,P15586,P62258,Q8N1B4,P50570,Q9UJW0,Q14789,Q01082,Q15363,P05067,Q9H9Q2,Q13813,O15260,Q9UPT5,Q9UIQ6,Q9UID3,Q12981,P61923,Q7Z6M1,Q13561,Q99627,Q96KP1,Q6NUQ1,P61163,Q8TD16,O14653,Q10471,Q8WVM8,P86790,Q92783,Q9BT78,O95721,Q96JB2,Q9Y6Y8,Q8N6H7,Q9UNS2,Q8TBA6,Q92734,Q07157,P33176,P61106,P53365,P52732,O60749,Q15643,P49755,Q9UP83,Q9H0H5,Q13190,Q8WUX9,O75935,Q92538,P35606,P83436,Q9NQT8 111 +Attachment of gpi anchor to upar 0.7097443237832339 1.5055161875700018 0.1321914182711694 1.0 0.5662508737958469 5 O43292,Q9H490 2 +Metabolism of steroid hormones 0.6082620351100929 1.475696642619855 0.1400253476697321 1.0 0.5726108597791065 7 P30536,Q14849,O95772 3 +Reduction of cytosolic ca levels 0.7511064751364291 1.4700302297168113 0.1415535668659768 1.0 0.5760925438424829 4 P20020,P23634 2 +Metabolism of cofactors 0.5685432162262294 1.4326260010998089 0.1519647470667895 1.0 0.594209299328016 8 P00374,O75208 2 +Alpha oxidation of phytanate 0.6900248254538712 1.4160634583329403 0.1567569256978735 1.0 0.594209299328016 5 Q9BY49,P51648 2 +Metal ion slc transporters 0.8790527206089567 1.40160214963494 0.1610340847276976 1.0 0.594209299328016 2 Q8TAD4 1 +Zinc transporters 0.8790527206089567 1.40160214963494 0.1610340847276976 1.0 0.594209299328016 2 Q8TAD4 1 +Inflammasomes 0.6858812518411407 1.3972229570893069 0.162346535257194 1.0 0.594209299328016 5 P05067,P09601 2 +The nlrp3 inflammasome 0.6858812518411407 1.3972229570893069 0.162346535257194 1.0 0.594209299328016 5 P05067,P09601 2 +Signaling by erbb4 0.5620502865430426 1.396461758184451 0.1625754887926409 1.0 0.594209299328016 8 P46934 1 +Trans golgi network vesicle budding 0.3758860133061013 1.390509763702732 0.1643741365289543 1.0 0.594209299328016 41 P55327,Q9BXS5,P02786,O95295,O43493,Q12846,P50570,P78537,P11717,O14964,P05067,P15586,O75976 13 +Copii mediated vesicle transport 0.3898769121204741 1.3904305121196492 0.1643981864673191 1.0 0.594209299328016 31 Q12907,Q9H0U4,O14653,Q8WVM8,P49755,O15498,Q15363,P49257,Q13190 9 +Complex i biogenesis 0.3915776064468034 1.3872787833397526 0.1653567701033214 1.0 0.594209299328016 30 O95139,Q86Y39,P03886,Q9P0J0,Q9NPL8,O43676 6 +Neutrophil degranulation 0.2763238596135113 1.3854626125168643 0.1659110570673456 1.0 0.594209299328016 183 P06756,Q93050,O00264,Q9NZJ7,P13473,Q9H7Z7,O75787,P04439,Q5T9A4,P30519,P06280,O95721,P16278,O15260,P12956,P17900,Q8NF37,Q13510,P10321,P27105,Q9NQX7,P07602,P10253,O00754,Q07065,P11279,Q969Q5,P10619,Q08722,Q92542,O00231,P08236,O00584,O00560,Q9BTY2,Q9NV96,Q13217,P15586,P42785 39 +Rsk activation 0.7300771639659117 1.379413660181003 0.1677672498992199 1.0 0.594209299328016 4 Q15418 1 +Gastrin creb signalling pathway via pkc and mapk 0.6367518312519727 1.3738036272598562 0.1695026547505975 1.0 0.594209299328016 6 Q15418 1 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5568867375215755 1.3676578800652206 0.1714191899277426 1.0 0.594209299328016 8 P51812,Q15418 2 +Basigin interactions 0.5865968409519624 1.3619505033056096 0.1732135062741875 1.0 0.594209299328016 7 P54709,P53985,P05026,P08195,P35613 5 +Initiation of nuclear envelope ne reformation 0.4520975410488348 1.3602211248308504 0.1737599595554333 1.0 0.594209299328016 17 P30153,P50402,Q86XL3,P42167,P20700,P02545,Q14739 7 +Amino acid transport across the plasma membrane 0.6763023969056817 1.353620899465117 0.1758573557172886 1.0 0.594209299328016 5 P30825,Q9H2J7 2 +Synaptic adhesion like molecules 0.6323942585751408 1.3526650535542015 0.176162659546025 1.0 0.594209299328016 6 O95197,P10586 2 +Acyl chain remodelling of pc 0.867211728221036 1.3522104183853612 0.1763080117819968 1.0 0.594209299328016 2 Q8NF37 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.450877437624665 1.3511490853860968 0.1766476804219019 1.0 0.594209299328016 17 P27824,P01889,P10321,Q03518,P04439,Q9NZ08 6 +Muscle contraction 0.387076488318508 1.343485568419294 0.1791147959481565 1.0 0.594209299328016 30 P54709,Q05682,P16615,Q13586,P20020,P09493,P04083,P05026,Q9HD47,Q13177,P08670,P23634,P67936,Q9NYL9,P05023 15 +The citric acid tca cycle and respiratory electron transport 0.3955686884334584 1.3410002049055012 0.1799203860714955 1.0 0.594209299328016 99 Q9UDW1,Q86Y39,O14949,P00846,O43676,Q8N8Q8,O95139,P56385,O14548,O75964,Q9P0J1,P00403,Q15118,P21912,Q16134,Q9NPL8,P06576,P03886,Q13423,P13073,P21796,O96000,Q9P0J0,P35613,P24539 25 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.6293117643671411 1.337702160739507 0.1809935463508534 1.0 0.594209299328016 6 Q9NR77,Q16850 2 +Pregnenolone biosynthesis 0.6706620200593002 1.327919836868374 0.1842045907241249 1.0 0.5954704727219821 5 Q14849,O95772 2 +Surfactant metabolism 0.8601635184662965 1.3228343916744794 0.1858904574201816 1.0 0.5981373221751421 2 Q07065 1 +Maturation of sars cov 1 spike protein 0.66751660955194 1.3135803215240234 0.1889874745529765 1.0 0.6038671571301383 5 P26572,P27824 2 +Hs gag degradation 0.8646362098138654 1.3115930292300482 0.1896574862771594 1.0 0.6038671571301383 3 P54802,P16278 2 +Erk mapk targets 0.5328066078250497 1.288879168993083 0.1974400970522289 1.0 0.6171090258086188 10 P51812,Q15418,P30154 3 +Mapk targets nuclear events mediated by map kinases 0.5328066078250497 1.288879168993083 0.1974400970522289 1.0 0.6171090258086188 10 P51812,Q15418,P30154 3 +Metabolism of folate and pterines 0.5322735179317899 1.2760986857143264 0.2019206361550565 1.0 0.6254144899583116 9 P00374 1 +Incretin synthesis secretion and inactivation 0.6554477974933179 1.2585253824265792 0.2082018135226779 1.0 0.6312785756168376 5 P67812 1 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.6554477974933179 1.2585253824265792 0.2082018135226779 1.0 0.6312785756168376 5 P67812 1 +Cardiac conduction 0.450350735529658 1.248197294556685 0.211958814489072 1.0 0.6349010882955843 15 P16615,Q13586,P20020,Q9HD47,P23634,P05023 6 +Nef mediated downregulation of mhc class i complex cell surface expression 0.6530773671526128 1.2477076089498769 0.2121381537919613 1.0 0.6349010882955843 5 P04439 1 +Anchoring of the basal body to the plasma membrane 0.3595743697001294 1.2404941601757 0.2147926728658407 1.0 0.636663915483929 39 Q15154,P30153,Q9H6D7,P07900,P61163,Q13561,O75935,Q96CS2,P41208,O94927,P62258,Q14203,O95684,Q15051,P53350 15 +Intrinsic pathway of fibrin clot formation 0.8401466027628965 1.2395644011016973 0.2151365546166648 1.0 0.636663915483929 2 P42785 1 +Formation of fibrin clot clotting cascade 0.8401466027628965 1.2395644011016973 0.2151365546166648 1.0 0.636663915483929 2 P42785 1 +Purinergic signaling in leishmaniasis infection 0.6953629688925486 1.2294632807776649 0.2188981568942243 1.0 0.639534892746532 4 P09601 1 +Keratan sulfate biosynthesis 0.8370453904708132 1.2266911142441923 0.2199387087105762 1.0 0.639534892746532 2 O43505 1 +Acyl chain remodelling of pg 0.8350718917395005 1.2185037320890089 0.2230326073994284 1.0 0.6414146606882538 2 Q8NF37 1 +Interactions of vpr with host cellular proteins 0.3661364641792613 1.2172749136742038 0.2234996356850667 1.0 0.6414146606882538 34 Q8NFH5,Q7Z3B4,Q8TEM1,P12236,Q8N1F7,Q8NFH4,Q9BTX1,O15504,P05141,P12235 10 +Wax and plasmalogen biosynthesis 0.6427765237020244 1.2006930556809887 0.2298702888639532 1.0 0.6535468973339639 5 O15228,Q6IAN0,Q96K12,Q8WVX9 4 +Translation of replicase and assembly of the replication transcription complex 0.6882685176630396 1.198815359611999 0.2305997487962696 1.0 0.6535468973339639 4 Q9Y3E7,Q8WUX9 2 +Heme signaling 0.5265299803479437 1.197751238388433 0.2310138754404751 1.0 0.6535468973339639 8 P09601 1 +Translation of sars cov 1 structural proteins 0.526368497584396 1.1968458137420537 0.2313666576294428 1.0 0.6535468973339639 8 Q10472,P26572,P27824 3 +Lysosome vesicle biogenesis 0.4349963359960306 1.1832142303588251 0.2367242546138388 1.0 0.6572218550158302 16 Q9BXS5,P78537,O14964,P05067,P15586 5 +Heme biosynthesis 0.5972004281628875 1.1815133790227748 0.2373988417155987 1.0 0.6572218550158302 6 P22830 1 +Metabolism of fat soluble vitamins 0.5945977955354287 1.168843077970514 0.2424668607428017 1.0 0.6609802314276673 6 P98164,Q07954,Q8N0U8 3 +Abacavir transport and metabolism 0.822948970961376 1.168300724735393 0.2426854831386995 1.0 0.6609802314276673 2 P49902 1 +Interleukin 4 and interleukin 13 signaling 0.4740159429368098 1.1666228029927268 0.2433627304111483 1.0 0.6615550085314549 12 Q07820,P09601 2 +Striated muscle contraction 0.5899029471070648 1.1459893332768287 0.2517995656376381 1.0 0.6709083050227307 6 P09493,P08670,P67936 3 +Regulation of pyruvate dehydrogenase pdh complex 0.5168571741128347 1.143510250035075 0.2528268014478982 1.0 0.6718375117126735 8 Q9P0J1 1 +Nuclear events kinase and transcription factor activation 0.4556382935304993 1.1403706947572694 0.2541318965451653 1.0 0.6727992445572427 13 P51812,Q15418,P30154 3 +Proton coupled monocarboxylate transport 0.8161826895968257 1.140358453268706 0.2541369944204947 1.0 0.6727992445572427 2 P35613 1 +Sars cov 1 infection 0.4349176899373001 1.138668471920087 0.2548414575460676 1.0 0.6734078738507819 15 Q8WUX9,Q10472,P27824,Q9UQN3,Q9Y3E7,P26572,P14314 7 +Phosphorylation of the apc c 0.454306520339321 1.1315277943300266 0.2578330117310923 1.0 0.67862322805822 13 Q16763,Q96DE5,Q9UJX5,Q9UJX4,P06493,P30260,Q9H1A4,Q13042,P53350 9 +Recruitment of numa to mitotic centrosomes 0.3540637018974503 1.127760218283171 0.2594211983219101 1.0 0.67862322805822 43 Q15154,P30153,P07900,Q9H6D7,P61163,Q13561,O75935,Q9BSJ2,Q96CS2,P41208,O94927,P53350,P62258,Q14203,O95684,Q9UGJ1 16 +Golgi associated vesicle biogenesis 0.3576336323709072 1.108812070932616 0.2675112620344047 1.0 0.6942112407862139 33 P55327,Q14677,Q9BXS5,P02786,O95295,P09496,O43493,P50570,O60749,P78537,Q14789,P11717,O75976 13 +G alpha i signalling events 0.3673756924023764 1.087685618917383 0.2767339185690742 1.0 0.7062687598012884 25 Q9NZJ7,P30154,P05067,P07602,P52292 5 +Cargo recognition for clathrin mediated endocytosis 0.3509139602802141 1.08281774200016 0.2788893288880265 1.0 0.7065884956577058 35 Q96D71,P02786,O43493,P98164,Q9UNS2,Q92905,P11717,Q99627,Q14108,O14964,Q9BT78 11 +Asparagine n linked glycosylation 0.3535744979454691 1.0706109685152367 0.2843443895321003 1.0 0.7103603675106519 130 Q9H3H5,Q96PC5,Q12907,P61163,P24390,O14653,Q8WVM8,Q9UJW0,Q14789,Q01082,P04843,Q15363,P46977,Q16706,Q13813,P16278,Q96JB2,Q9Y6Y8,Q9H0U4,Q8N6H7,O15020,P62820,Q9BUN8,Q86TM6,Q86YN1,P15291,O95249,P49755,P61923,O15498,O60476,Q9BT22,Q14203,O43731,Q9UP83,P49257,P26572,P14314,P10619,Q8WTW3,Q13190,Q9GZP9,Q13561,Q5JRA6,Q13438,O75935,P27824,P04844,P04066,Q9UBV2,P54727,Q96AA3 52 +Glutamate neurotransmitter release cycle 0.653878702397747 1.0506256310131978 0.2934305644347603 1.0 0.7203771123407006 4 Q96QD8,O75915,Q13136 3 +Synthesis of pg 0.794134235758603 1.0370030207832976 0.2997344493430081 1.0 0.7209961130334105 3 Q8N2A8,Q8IV08 2 +Abc family proteins mediated transport 0.3604560478393508 1.0367074070428557 0.2998722389523098 1.0 0.7209961130334105 58 P49721,O00231,P33897,Q9GZP9,P28072,Q13438,Q9BUN8,P28070,Q9UL46,Q9NP58,O75027,P61289,Q99758,P08183,P40855,Q9UBV2,P33527 17 +Organelle biogenesis and maintenance 0.366672265519747 1.0323672585098438 0.3019001039772704 1.0 0.7209961130334105 110 Q15154,P54619,Q16891,Q04837,Q96CS2,P62258,P00846,Q5XKP0,Q9H6D7,Q13505,P07900,Q9UPT5,P56385,A6NIH7,O75964,Q6UXV4,Q96A65,O95684,P06576,Q15051,P53350,P78371,P30153,Q9NX63,Q15643,P41208,O94927,Q96RR1,Q14203,Q96RS0,Q9NVH1,Q9Y512,A0AVF1,Q9Y366,Q10713,Q13561,O75935,Q92973,Q9BUR5,Q96KP1,P24539 41 +Nephrin family interactions 0.5179509374151459 0.9995415273870092 0.3175324326251409 1.0 0.7237388621318762 7 Q01082,Q13813,O43707 3 +Pyruvate metabolism 0.4095412757128073 0.9980975375388322 0.3182320640825722 1.0 0.7237388621318762 16 P35613,Q9P0J1,P21796 3 +Transferrin endocytosis and recycling 0.4474776386509346 0.9976357357172384 0.3184560258993549 1.0 0.7237388621318762 12 P02786,P36543,Q93050,Q15904,Q9Y487 5 +Copi mediated anterograde transport 0.3576309277026898 0.9879399822561326 0.3231820426669847 1.0 0.7281470813032853 60 P61163,P24390,O14653,Q9UJW0,Q14789,Q01082,Q15363,Q13813,Q96JB2,Q9H0U4,Q8N6H7,O15020,P62820,O95249,P49755,P61923,O15498,Q14203,Q9UP83,O43731,Q13190,Q8WTW3,Q13561,O75935,Q92538,P35606 26 +Aurka activation by tpx2 0.3360131561073786 0.9846047531309626 0.3248182540274698 1.0 0.7281470813032853 39 Q15154,P30153,Q9H6D7,P07900,P61163,Q13561,O75935,Q96CS2,P41208,O94927,P62258,Q14203,O95684,P53350 14 +Transport to the golgi and subsequent modification 0.3678949193878716 0.9801457375142498 0.3270141849893471 1.0 0.730396386267122 87 Q96PC5,Q12907,P61163,P24390,O14653,Q8WVM8,Q9UJW0,Q14789,Q01082,Q15363,Q16706,Q13813,Q96JB2,Q9Y6Y8,Q9H0U4,Q8N6H7,O15020,P62820,P15291,O95249,P49755,P61923,O15498,O60476,Q14203,O43731,Q9UP83,P49257,P26572,Q13190,Q8WTW3,Q13561,Q5JRA6,O75935,P04066 35 +Linoleic acid la metabolism 0.6364093107906224 0.975820385996981 0.3291534805372476 1.0 0.730396386267122 4 P33897,O60427 2 +Synthesis of pc 0.5918975846138426 0.9692184375275869 0.3324362137562846 1.0 0.730396386267122 5 Q9NQZ5 1 +Prevention of phagosomal lysosomal fusion 0.633850493653034 0.9649040834718062 0.3345928559501501 1.0 0.730396386267122 4 Q9H267,P51149,O14964 3 +Synthesis of pips at the golgi membrane 0.4845815706180272 0.9628925665776216 0.3356014403426099 1.0 0.730396386267122 8 Q9BTU6,Q10713 2 +Pre notch expression and processing 0.4583677684118241 0.955349342944478 0.3394010623222878 1.0 0.7342665375274416 11 Q15363,P16615,Q9UBV2 3 +Beta oxidation of pristanoyl coa 0.6298782422086917 0.9479820151207836 0.3431386100827001 1.0 0.7388675079018989 4 P22307,O15254 2 +Iron uptake and transport 0.3883477845551346 0.9387280664958628 0.3478703795488016 1.0 0.7467898163082443 19 Q93050,P09601,Q15904,Q9Y487,P30519 5 +G1 s specific transcription 0.4547566064432724 0.9335675615547868 0.3505270046992472 1.0 0.7501032351630297 11 P00374 1 +Ecm proteoglycans 0.7662272801520997 0.930015576249697 0.3523630197728535 1.0 0.7501032351630297 3 P05067 1 +Wnt ligand biogenesis and trafficking 0.5448777079791107 0.92762561116329 0.3536018078253731 1.0 0.7501032351630297 6 Q5T9L3 1 +Ubiquinol biosynthesis 0.6243242811817673 0.9243748804854084 0.3552911684893232 1.0 0.7512056283868018 4 O75208 1 +Insulin receptor recycling 0.4527983777802931 0.9217704176034408 0.3566483410205647 1.0 0.7512056283868018 11 Q15904,Q9Y487,Q93050 3 +Cell surface interactions at the vascular wall 0.3932013255427471 0.9211588192693804 0.3569675148498104 1.0 0.7512056283868018 17 Q08722,P06756,Q92896,P53985,P35613 5 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.5018271555243076 0.9148643476423456 0.3602628486988228 1.0 0.7529549906085115 7 P30153,P30154 2 +Beta catenin phosphorylation cascade 0.5018271555243076 0.9148643476423456 0.3602628486988228 1.0 0.7529549906085115 7 P30153,P30154 2 +Signaling by ctnnb1 phospho site mutants 0.5018271555243076 0.9148643476423456 0.3602628486988228 1.0 0.7529549906085115 7 P30153,P30154 2 +Cytochrome p450 arranged by substrate type 0.7609648037908648 0.9100197797691894 0.3628120785002529 1.0 0.7529549906085115 3 Q16850 1 +Pp2a mediated dephosphorylation of key metabolic factors 0.7596929091865918 0.905196827553877 0.3653611222620458 1.0 0.7529549906085115 3 P30154 1 +Binding and uptake of ligands by scavenger receptors 0.4735074878608417 0.9012955335981508 0.3674312079070914 1.0 0.7530634411514383 8 Q5KU26,Q8WTV0,P07900,Q07954 4 +Rho gtpase cycle 0.2824234311484923 0.8982303170033926 0.3690627736723961 1.0 0.7535252889800435 170 Q9UEY8,P62995,Q8WVM8,Q9Y6M7,Q92783,Q01082,Q96CS3,Q5JTV8,Q6IAA8,P30519,Q9BT78,P51572,P67936,Q14155,Q13813,O75976,P42166,P07900,P51648,Q13505,P07910,Q9Y5S2,Q15058,Q9P0I2,P27105,Q07021,O75955,O95202,Q8N5V2,P78371,P12814,P02786,O15173,P50402,Q8NBN3,Q14185,P42167,O15498,Q07065,P38159,P49257,P08670,Q16543,Q9Y512,Q13190,Q86UP2,Q96HY6,Q8TAA9,Q86XL3,Q8N684,P20700,Q15904,Q14739,O14964,Q86VI3,Q86YQ8 56 +Metabolism of steroids 0.3421859269158018 0.8820571408624378 0.3777459077407541 1.0 0.7645592040757759 53 Q9H2C2,Q16850,P38435,Q53GQ0,O75845,P04062,Q9HCL2,P30536,Q14534,P04035,Q15125,Q14849,Q14739,Q96RS0,Q15800,Q15392,O95772,P37268 18 +G2 m dna replication checkpoint 0.6141043723554249 0.8811170768943262 0.3782544552534119 1.0 0.7645592040757759 4 P14635,Q99640,P06493 3 +Cs ds degradation 0.7510572314631934 0.8760098949815115 0.381024654554146 1.0 0.7656291908430469 2 P06865 1 +Bicarbonate transporters 0.7507753030730009 0.8748904490938127 0.3816335163051145 1.0 0.7656291908430469 2 Q9Y6M7 1 +Reactions specific to the complex n glycan synthesis pathway 0.7504933746828344 0.8737712783334612 0.3822428248022929 1.0 0.7656291908430469 2 Q16706 1 +Collagen biosynthesis and modifying enzymes 0.4447490532343182 0.8734019955297382 0.3824440037091734 1.0 0.7656291908430469 11 P13674,P07237,Q32P28 3 +N glycan antennae elongation in the medial trans golgi 0.750705019740545 0.8712317728189543 0.3836276148110058 1.0 0.7656291908430469 3 Q16706,P15291 2 +Trafficking and processing of endosomal tlr 0.7496475895122704 0.8704154254228137 0.3840734198682927 1.0 0.7656291908430469 2 Q99538 1 +Cdc42 gtpase cycle 0.3279978286262885 0.8702505724887452 0.3841634840593724 1.0 0.7656291908430469 41 P42166,P02786,Q86YQ8,Q9Y5S2,Q86UP2,Q8N6H7,Q8TAA9,P42167,O15498,Q14739,Q6IAA8,P27105,Q9H0H5,Q86VI3,Q14155,Q8N5V2,Q13576 17 +Synthesis secretion and deacylation of ghrelin 0.7475924739164541 0.8595197004548477 0.3900538558187354 1.0 0.7668273168361938 3 P67812 1 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.7475924739164541 0.8595197004548477 0.3900538558187354 1.0 0.7668273168361938 3 P67812 1 +Activation of nmda receptors and postsynaptic events 0.3404539460692832 0.839421607441106 0.4012327628437555 1.0 0.7782632496165163 25 P51812,P07196,P54619,Q14012,P10644,Q15418,Q14155,P52292 8 +Regulation of glucokinase by glucokinase regulatory protein 0.3387595583353333 0.8389952926539174 0.4014719511763847 1.0 0.7782632496165163 27 Q12769,Q8NFH5,Q7Z3B4,Q8TEM1,P57740,Q8N1F7,Q9BTX1,Q92621,P12270,O15504,Q99567,P35658,Q8NFH4 13 +Apc c cdc20 mediated degradation of cyclin b 0.4086286250359525 0.8299503719335066 0.4065668433951352 1.0 0.7793302033638341 13 Q16763,Q96DE5,Q9UJX5,Q9UJX4,P30260,P06493,Q9H1A4,Q13042 8 +Sumoylation of sumoylation proteins 0.3365426195246299 0.8274872460546443 0.407960948017954 1.0 0.7793302033638341 28 Q12769,Q8NFH5,Q7Z3B4,Q8TEM1,P57740,Q8N1F7,Q9BTX1,Q92621,P12270,O15504,Q99567,P35658,Q8NFH4 13 +Glycogen breakdown glycogenolysis 0.4589329107569072 0.8207717153603628 0.4117763125102276 1.0 0.7793302033638341 8 P10253 1 +Abc transporter disorders 0.32902667369641 0.8051494801511847 0.4207334255143187 1.0 0.7813662995347815 47 P49721,O00231,P33897,Q9GZP9,P28072,Q13438,Q9BUN8,P28070,Q9UL46,Q99758,P61289,O14678,Q9UBV2 13 +Nuclear envelope breakdown 0.3236000062649899 0.7962351578715005 0.4258953661056479 1.0 0.7838463352839357 43 P42166,Q8NFH5,Q7Z3B4,Q8TEM1,P50402,P42167,Q8N1F7,P02545,P20700,Q9BTX1,Q8NFH4,O15504,P53350 13 +Postmitotic nuclear pore complex npc reformation 0.348571113822278 0.793168850784894 0.4276794531048091 1.0 0.7847875808531865 23 Q8NFH5,Q7Z3B4,Q8N1F7,Q9BTX1,Q92973 5 +Cohesin loading onto chromatin 0.4466519615713511 0.7916830390172404 0.428545514430396 1.0 0.7847875808531865 10 Q29RF7,Q8WVM7,Q7Z5K2,Q8N3U4,Q9Y6X3 5 +Mtor signalling 0.3729210227241089 0.7717501427198576 0.4402624261198156 1.0 0.7972437759194978 17 P23588,P42345,P62942 3 +Synthesis of pe 0.7236553802453616 0.7704374835931859 0.4410404257200886 1.0 0.7972437759194978 3 Q9HBU6 1 +Plasma lipoprotein clearance 0.3823348501001671 0.7682016424247567 0.4423673978944511 1.0 0.7986251114659365 15 P09496,P61916,Q6PIU2,Q8WTV0,O15118 5 +Phosphorylation of emi1 0.5856135401974607 0.7621080386589884 0.4459955254818588 1.0 0.7989370472211121 4 P14635,P53350,P06493 3 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3607904485085305 0.7556869564797493 0.4498369062621101 1.0 0.7989370472211121 20 Q9BT22,Q86YN1,P16278,P10619 4 +Nuclear envelope ne reassembly 0.3265975054503566 0.7553457413863444 0.450041559949212 1.0 0.7989370472211121 49 Q8NFH5,P30153,Q7Z3B4,P50402,Q86XL3,P42167,Q8N1F7,P02545,P20700,Q9BTX1,Q9Y3E7,Q14739,Q92973,Q8NFH4 14 +Establishment of sister chromatid cohesion 0.4464018528302783 0.7522157289444915 0.4519213361964067 1.0 0.7989370472211121 8 Q7Z5K2,Q8N3U4,Q29RF7,Q8WVM7 4 +Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.7189173949816807 0.7503818888138293 0.4530247356608523 1.0 0.7989370472211121 2 P49327 1 +Hyaluronan uptake and degradation 0.5418136408292678 0.7458469879094903 0.4557598517907457 1.0 0.7994106671088606 5 P08236,P06865 2 +Hyaluronan metabolism 0.5418136408292678 0.7458469879094903 0.4557598517907457 1.0 0.7994106671088606 5 P08236,P06865 2 +Extracellular matrix organization 0.3254103333039221 0.7425564151901018 0.4577502843632608 1.0 0.8009218908896019 30 Q92542,Q08722,P07237,P06756,Q32P28,P05067,P13674,P35613 8 +Collagen formation 0.3944393560940162 0.7379019067381489 0.4605740602135548 1.0 0.8038801862767949 13 P13674,P07237,Q32P28 3 +Energy dependent regulation of mtor by lkb1 ampk 0.436555323224521 0.7315630414998194 0.4644353132074119 1.0 0.8075586712732941 9 Q9Y2Q5,P54619,P42345,Q6IAA8 4 +Pi metabolism 0.3635459393763741 0.7225068219157184 0.4699829326636444 1.0 0.813299733475258 18 Q9BTU6,Q9NZC3,Q10713,Q8TBX8 4 +Golgi cisternae pericentriolar stack reorganization 0.4030233911382431 0.7187550239260642 0.472291873924602 1.0 0.814605712675587 12 P61019,P62820,Q9H0U4 3 +Ion homeostasis 0.3911561348727327 0.7167949619917432 0.4735006207861989 1.0 0.814605712675587 13 P16615,Q13586,P20020,P23634,P05023 5 +Receptor type tyrosine protein phosphatases 0.7096137581054485 0.7148776067467351 0.4746846752551059 1.0 0.814605712675587 2 P10586 1 +Rhoj gtpase cycle 0.3244915577950896 0.7141814708505706 0.4751149729577855 1.0 0.814605712675587 28 P42166,P02786,Q9Y5S2,Q8TAA9,Q96RU3,P51149,P42167,Q5T2T1,Q9Y6M7,Q6IAA8,P27105,Q86YQ8,Q86VI3,Q14155,Q13177 15 +Rac3 gtpase cycle 0.3160084004283666 0.7045023600376161 0.4811199808532049 1.0 0.8150081775516668 34 P42166,P02786,O15173,P50402,Q8TAA9,Q9UQB8,P51149,P42167,Q5T2T1,O15498,Q14739,Q6IAA8,Q9H0H5,Q15758,P49257,Q13177 16 +Dna damage recognition in gg ner 0.3576154580069308 0.7017157130628608 0.4828564718300945 1.0 0.8150081775516668 19 Q9UNS2,Q92905,P41208,Q99627,Q9BT78,P54727 6 +Toll like receptor 9 tlr9 cascade 0.3249100616677554 0.6982044120931288 0.4850493676360017 1.0 0.8150081775516668 25 P05067,P30154,Q15418,P51812 4 +Amyloid fiber formation 0.4359323072686931 0.6955637670480836 0.4867020638168791 1.0 0.8153839770438625 8 Q92542,P05067,Q9Y287 3 +Dap12 interactions 0.4946056419340512 0.6891964630633939 0.4906996423045509 1.0 0.8173316793368304 6 P10321 1 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.5662871125689549 0.6831273388713202 0.4945263815476597 1.0 0.817757633179683 4 O14734,P22307 2 +Hs gag biosynthesis 0.6976875352509658 0.6761887015948314 0.4989208450475719 1.0 0.8216593086843995 3 O94923,Q7LGA3 2 +Er to golgi anterograde transport 0.3396386087116843 0.6594132756010129 0.5096304194762351 1.0 0.830160809818469 81 Q96PC5,Q12907,P61163,P24390,O14653,Q8WVM8,Q9UJW0,Q14789,Q01082,Q15363,Q13813,Q96JB2,Q9Y6Y8,Q9H0U4,Q8N6H7,O15020,P62820,Q92734,O95249,P49755,P61923,O15498,Q14203,O43731,Q9UP83,P49257,Q13190,Q8WTW3,Q13561,Q5JRA6,O75935,Q92538,P35606 33 +Maturation of sars cov 2 spike protein 0.3933003527340041 0.6592728035053287 0.509720603373341 1.0 0.830160809818469 12 P27824,P04844,P04843,P46977,Q16706,P26572 6 +Synthesis of substrates in n glycan biosythesis 0.3664511319262873 0.6591453940649875 0.5098024081936139 1.0 0.830160809818469 15 Q86YN1,P10619 2 +Export of viral ribonucleoproteins from nucleus 0.3174291652005029 0.6567864850288248 0.5113182154907272 1.0 0.830160809818469 29 Q12769,Q8NFH5,Q7Z3B4,Q8TEM1,P57740,Q8N1F7,Q9BTX1,Q92621,P12270,O15504,Q99567,P35658,Q8NFH4 13 +Toll like receptor tlr1 tlr2 cascade 0.3310627127321146 0.6445225913967008 0.5192366128990777 1.0 0.838221562802948 23 P05067,P30154,Q15418,P51812 4 +Signaling by braf and raf1 fusions 0.3307956240979269 0.6422838251615794 0.5206889144971345 1.0 0.8395214091848838 23 P51114,Q9NRY5,Q53H12,P51797,Q96PU8 5 +Sialic acid metabolism 0.5169816631981053 0.6385946142365699 0.5230866858657268 1.0 0.840611559732125 5 P10619 1 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4017171840887471 0.6203344720257771 0.5350376041203839 1.0 0.8463972800967946 11 Q16763,Q96DE5,Q9UJX5,Q9UJX4,Q9H1A4,Q13042 6 +N glycan trimming and elongation in the cis golgi 0.681322167637116 0.6183707142990141 0.536330997868401 1.0 0.8471779361748268 3 O60476 1 +Disorders of transmembrane transporters 0.3355008685360277 0.6155355081441186 0.5382011270723439 1.0 0.8471779361748268 80 P33897,P53985,Q8N1F7,P28070,Q9BTX1,O14678,O00400,Q7Z3B4,Q9BUN8,Q9UL46,Q8NFH5,P49721,P28072,P61289,O00231,Q9GZP9,Q13438,Q99758,Q9UBV2,P35613,Q8NFH4 21 +Cilium assembly 0.330002155048285 0.6049888700062295 0.5451863919873392 1.0 0.8480084556174361 70 Q15154,P61163,Q96CS2,P07900,Q9H6D7,Q9UPT5,A6NIH7,Q96A65,O95684,Q15051,P53350,P78371,P30153,Q15643,P41208,O94927,Q14203,A0AVF1,Q9Y366,Q10713,Q13561,O75935,Q92973,Q96KP1,P62258 25 +Peroxisomal lipid metabolism 0.3611934706216639 0.5987930912820673 0.5493108699623024 1.0 0.8528141405651062 14 O43808,Q9BY49,P33897,P51648 4 +Tp53 regulates transcription of cell death genes 0.4726401466014407 0.5886909761536584 0.5560685923842881 1.0 0.8586086317663817 6 Q9Y255 1 +Dna replication initiation 0.4150574074008721 0.5848411391353859 0.5586545395615339 1.0 0.8608349957294112 8 Q9NR33 1 +Rhof gtpase cycle 0.3443781096895923 0.5821352996216114 0.5604755497860614 1.0 0.8608349957294112 18 P42166,Q9UEY8,Q8TAA9,P42167,P20700,Q9Y6M7,Q5JTV8 7 +Signaling by erbb2 in cancer 0.5407720020777766 0.5817799788280823 0.5607148915062004 1.0 0.8608349957294112 4 Q16543 1 +Signaling by erbb2 ecd mutants 0.5407720020777766 0.5817799788280823 0.5607148915062004 1.0 0.8608349957294112 4 Q16543 1 +Ripk1 mediated regulated necrosis 0.3694058640977182 0.579408888985688 0.5623133076714977 1.0 0.8608349957294112 13 O75955,P49327,O00560,Q16543 4 +Vxpx cargo targeting to cilium 0.4084771027800895 0.57856396025491 0.562883428472045 1.0 0.8608349957294112 9 Q96KP1,Q96A65,Q9UPT5 3 +Regulation of tp53 expression and degradation 0.3562586293846667 0.5667546873413708 0.5708808601875734 1.0 0.8657792774826498 14 P30153,P30154 2 +Interaction between l1 and ankyrins 0.5368242264299696 0.5664545058599003 0.5710848511090629 1.0 0.8657792774826498 4 Q01082,O15020 2 +Mitotic telophase cytokinesis 0.3665766100433295 0.5619125542839603 0.5741755996747167 1.0 0.8695359401690747 13 Q29RF7,Q8WVM7,Q7Z5K2,Q8N3U4,Q9Y6X3,P53350 6 +Constitutive signaling by overexpressed erbb2 0.6631850266617009 0.5559938840464059 0.5782150357414655 1.0 0.8728586550182335 3 Q16543 1 +Ns1 mediated effects on host pathways 0.301937247462871 0.551495382606597 0.5812941310756923 1.0 0.8732419710512267 33 Q8NFH5,Q7Z3B4,Q8TEM1,Q8N1F7,Q8NFH4,Q9BTX1,O15504,P52292 8 +Ctla4 inhibitory signaling 0.4296575021009405 0.5480943668443364 0.5836271083442572 1.0 0.8732419710512267 7 P30154 1 +Synthesis of bile acids and bile salts 0.4057765950133652 0.5368090692688411 0.591399506409662 1.0 0.8755700633504034 8 Q96SU4,O14975,O14734,Q9H1P3,P22307 5 +Bile acid and bile salt metabolism 0.4057765950133652 0.5368090692688411 0.591399506409662 1.0 0.8755700633504034 8 Q96SU4,O14975,O14734,Q9H1P3,P22307 5 +Transcriptional regulation by ventx 0.34419831244007 0.5110158255464441 0.6093399753556212 1.0 0.8833583757015343 15 Q16763,Q96DE5,Q9UJX5,Q9UJX4,P30260,Q9HCE1,Q9H1A4,Q96KQ7,Q13042 9 +Mitotic prophase 0.3172818602915326 0.5092845789402161 0.6105527655747833 1.0 0.8833583757015343 64 Q8TEM1,Q8N1F7,P02545,Q9BTX1,O15504,P61019,P42166,Q7Z3B4,Q9H0U4,Q01105,P62820,P30154,P12270,P53350,Q8NFH5,P30153,P50402,P42167,P20700,Q8NFH4 20 +Activation of rac1 downstream of nmdars 0.6481425712269415 0.505809893551996 0.6129901124817749 1.0 0.8833583757015343 3 Q14012 1 +Lipophagy 0.48419864559817 0.5027343341972925 0.6151510668466791 1.0 0.8833583757015343 5 P54646,Q9Y478,P54619,O60664 4 +Non integrin membrane ecm interactions 0.4825164808256897 0.4959831820884368 0.619906276614677 1.0 0.8833583757015343 5 P06756,P05556,P12814 3 +Syndecan interactions 0.4825164808256897 0.4959831820884368 0.619906276614677 1.0 0.8833583757015343 5 P06756,P05556,P12814 3 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.4810940488126581 0.4902934121620286 0.6239262880572614 1.0 0.8844669358174364 5 P30154 1 +Activation of bad and translocation to mitochondria 0.4167137210615597 0.4861344953362287 0.6268718108734903 1.0 0.8859871510253813 7 P63104,P31751,P61981,Q04917,P31946,P62258 6 +Autophagy 0.3094497413059206 0.4779768421506359 0.6326666876500431 1.0 0.8879577772753628 58 Q15388,Q96B49,Q8N4H5,Q9NS69,P13473,Q8IWA4,P21796,P08670 8 +Bmal1 clock npas2 activates circadian gene expression 0.5130021905745474 0.4763937292590713 0.63379390126666 1.0 0.8879577772753628 4 Q96RS0 1 +Dopamine neurotransmitter release cycle 0.6425148012404918 0.4747917294062218 0.6349354285628952 1.0 0.8879577772753628 2 Q13136 1 +Phase i functionalization of compounds 0.3407392773122465 0.4682677841042081 0.6395931036397704 1.0 0.8879577772753628 14 O43169,Q16850 2 +Apoptotic factor mediated response 0.389062818574298 0.4526434767803267 0.6508054867446389 1.0 0.896595131738488 8 Q9NR28 1 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.3335770346878657 0.4429466300734121 0.6578043382229304 1.0 0.9002387744410494 15 P05067,P09601 2 +Hcmv late events 0.2835971711842137 0.4428265506184514 0.6578911973892658 1.0 0.9002387744410494 38 Q8TEM1,Q8N1F7,Q9UQN3,Q9BTX1,Q9BRG1,O15504,Q12769,Q9HD42,Q7Z3B4,Q92621,P12270,P35658,O75694,Q8NFH5,P61978,P57740,Q8WUX9,Q9Y3E7,Q99567,Q8NFH4 20 +Mtorc1 mediated signalling 0.3678428381330661 0.4327865515121115 0.6651698443618073 1.0 0.9056220398948672 11 P42345,P62942 2 +Signaling by gpcr 0.2959006216759675 0.4304711737152277 0.6668529313453473 1.0 0.9056220398948672 49 P51812,P30153,Q9NZJ7,P30154,P42892,P05067,Q15418,P07602,Q8N5V2,P52292 10 +Signaling by flt3 fusion proteins 0.4297685757939595 0.4034552488578059 0.6866133497380096 1.0 0.9178595571829852 6 Q14789,Q15643 2 +Glutathione conjugation 0.3237748386938628 0.402292053599054 0.6874691021033268 1.0 0.9178595571829852 16 O15217 1 +Rab geranylgeranylation 0.3002323974579908 0.3948440816224119 0.6929579601529778 1.0 0.9178595571829852 23 Q9BZG1,P61026,Q9H0U4,P62820,Q13637,Q969Q5,P61019 7 +Hedgehog ligand biogenesis 0.2850907744675629 0.3924830757377436 0.6947013138932532 1.0 0.9178595571829852 43 P49721,P07237,O00231,Q9GZP9,P28072,Q13438,P61289,Q86TM6,Q9UBV2 9 +Myd88 independent tlr4 cascade 0.2875225376268693 0.376004722071845 0.7069133854875922 1.0 0.9211295629080748 26 P05067,P30154,Q15418,P51812 4 +Platelet sensitization by ldl 0.4210653095209216 0.3681800684669726 0.7127389711767764 1.0 0.92447586846421 6 P30154 1 +Erks are inactivated 0.3878304480684151 0.3547959548923175 0.7227424590247586 1.0 0.932481746776366 7 P30154 1 +Inla mediated entry of listeria monocytogenes into host cells 0.6027628982238614 0.3503199447802748 0.7260985987156401 1.0 0.9337013248883388 2 O60716 1 +Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.3513079846602245 0.347247387062982 0.7284054733272662 1.0 0.9337013248883388 11 P04439 1 +Nuclear pore complex npc disassembly 0.2809923560195832 0.339999229929723 0.7338571078481728 1.0 0.9373026426971712 31 Q12769,Q8NFH5,Q7Z3B4,Q8TEM1,P57740,Q8N1F7,P06493,Q9BTX1,Q92621,P12270,O15504,Q99567,P35658,Q8NFH4 14 +Sumoylation of rna binding proteins 0.2771907770391673 0.3206996847810894 0.7484379861892365 1.0 0.9473983072279452 33 Q8NFH5,Q7Z3B4,P07910,Q8TEM1,Q8N1F7,Q9BTX1,P12270,O15504,Q8NFH4 9 +Ros and rns production in phagocytes 0.3557976576633016 0.3129348133490865 0.7543301877175652 1.0 0.9524384873367082 10 Q9Y487,Q93050 2 +Rhobtb1 gtpase cycle 0.3031667200913302 0.3119158072237486 0.7551045089878765 1.0 0.9524384873367082 19 P07910,Q8N684,Q9BT78,P38159,P08670,P78371 6 +Signaling by wnt in cancer 0.3532623473872326 0.3030771362682833 0.7618310778136661 1.0 0.95487127748009 9 P30154 1 +Glycogen metabolism 0.3418379416164965 0.3005437394128184 0.7637624382945047 1.0 0.95487127748009 11 P10253 1 +Ncam signaling for neurite out growth 0.3735618321188981 0.29426456137955 0.7685557503328191 1.0 0.9587492220899152 7 Q01082,O15020 2 +Protein protein interactions at synapses 0.3086986137452688 0.2927110847239002 0.7697429964370719 1.0 0.9587492220899152 15 O95197,Q13136,Q9Y2J2,P10586,O75955,Q14168 6 +Constitutive signaling by egfrviii 0.4272524982057024 0.2902907606103627 0.7715938066431876 1.0 0.9587492220899152 5 Q16543 1 +Signaling by egfr in cancer 0.4272524982057024 0.2902907606103627 0.7715938066431876 1.0 0.9587492220899152 5 Q16543 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.4272524982057024 0.2902907606103627 0.7715938066431876 1.0 0.9587492220899152 5 Q16543 1 +Cyclin a b1 b2 associated events during g2 m transition 0.3178508908192703 0.2812923133253252 0.7784862054788346 1.0 0.964778974300844 13 Q99640,P30153,P30154 3 +Myoclonic epilepsy of lafora 0.5742881308147839 0.2717568470655 0.7858089878746126 1.0 0.9681569376162856 2 P13807 1 +Rora activates gene expression 0.4519356281060436 0.2702119335880762 0.7869972123939477 1.0 0.9681569376162856 4 Q96RS0 1 +Plasma lipoprotein assembly remodeling and clearance 0.2935907988119273 0.2629499106756863 0.792589186308899 1.0 0.9687201165997652 20 O15118,Q8WTV0 2 +Rhoq gtpase cycle 0.2730243382262298 0.261495087955722 0.7937107370264409 1.0 0.9692560549402062 28 P02786,Q9Y5S2,Q8TAA9,Q96RU3,P51149,Q5T2T1,Q9Y6M7,Q6IAA8,P27105,Q86YQ8,Q86VI3,Q14155,Q13177 13 +Defective cftr causes cystic fibrosis 0.2709739449395686 0.2551985529641282 0.7985697486452574 1.0 0.9706703241104104 43 P49721,P28072,Q13438,Q9BUN8,Q9UBV2 5 +Regulation of localization of foxo transcription factors 0.4164785553047361 0.254585052071182 0.7990436055734333 1.0 0.9706703241104104 5 P63104,P61981,P31751,P31946 4 +Cytoprotection by hmox1 0.2970216540125854 0.2544005995689944 0.7991860878100265 1.0 0.9706703241104104 70 P49721,O00231,O75880,Q9Y6N1,O14548,P09601,P28072,Q96I36,P00403,P28070,Q9UL46,P61289,P13073,P30519,P33527,Q8N8Q8,Q96RS0 17 +Cyclin d associated events in g1 0.3427187473083977 0.2537907374579348 0.7996572296582591 1.0 0.9706703241104104 10 P30154 1 +Synthesis of pips at the late endosome membrane 0.5641387087679866 0.2461529512136575 0.8055638346193674 1.0 0.9737831287111832 2 O00443 1 +Signaling by retinoic acid 0.3405490879898624 0.2443258093219452 0.8069784961166693 1.0 0.9737831287111832 10 Q8NBN7,Q15118 2 +Negative regulation of nmda receptor mediated neuronal transmission 0.4106304771382805 0.2359136472696756 0.8134996781238708 1.0 0.9799287294208596 5 P07196,Q14012 2 +Interleukin 17 signaling 0.2877456510370971 0.2255281358758301 0.8215684398363443 1.0 0.9813178586934111 20 P51812,P30154,Q15418 3 +Costimulation by the cd28 family 0.2960399983513057 0.2224943651542043 0.8239290593050479 1.0 0.9833097856634676 15 P30153,P30154 2 +Chaperone mediated autophagy 0.353871232424791 0.2165086124272816 0.8285913126170685 1.0 0.9863851280231714 7 P08670 1 +Sumoylation of ubiquitinylation proteins 0.2660474761834093 0.2106854369869456 0.8331327391441095 1.0 0.9882517906787126 30 Q12769,Q8NFH5,Q7Z3B4,Q8TEM1,P57740,Q8N1F7,Q9BTX1,Q92621,P12270,O15504,P14373,Q99567,P35658,Q8NFH4 14 +Signaling by insulin receptor 0.2882606549950562 0.2077388322052489 0.8354328953330468 1.0 0.9882517906787126 17 Q15904,Q9Y487,Q93050 3 +Copi dependent golgi to er retrograde traffic 0.2785246229766516 0.2073572056027608 0.8357309012082137 1.0 0.9882517906787126 54 O15260,Q6NUQ1,Q9H0U4,Q8N6H7,P24390,P52732,P62820,P49755,Q12981,Q92538,P61923,Q15363,P35606,Q9P2W9,O43731,Q9H0H5,P33176 17 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.3287402607779833 0.1946843156335596 0.8456400912806123 1.0 0.990068720732004 10 O60725 1 +Nuclear import of rev protein 0.2620877421422083 0.1824195708720181 0.8552534681462385 1.0 0.9947579272946824 31 Q12769,Q8NFH5,Q7Z3B4,Q8TEM1,P57740,Q8N1F7,Q9BTX1,Q92621,P12270,O15504,Q99567,P35658,Q8NFH4 13 +Regulated necrosis 0.2820392575774841 0.181037833901351 0.856337879481806 1.0 0.9952034815599368 19 P07900,Q8WUX9,P49327,O00560,Q9Y3E7,O75955,Q16543 7 +Aflatoxin activation and detoxification 0.4194441694338255 0.179513755569693 0.8575343173837944 1.0 0.9957783930995124 4 Q9UJ14 1 +Transport of the slbp dependant mature mrna 0.2610107287212612 0.1775674626912974 0.8590626794166978 1.0 0.9960834534348464 32 Q12769,Q8NFH5,Q7Z3B4,Q8TEM1,P57740,Q8N1F7,Q9BTX1,Q92621,P12270,O15504,Q99567,Q86V81,P35658,Q8NFH4 14 +Nr1h2 and nr1h3 mediated signaling 0.3430720212269837 0.1770733608882139 0.8594507661865873 1.0 0.9960834534348464 7 Q8NB78,P49327 2 +The role of nef in hiv 1 replication and disease pathogenesis 0.2961800668893605 0.1741085386162503 0.8617801628474828 1.0 0.99623890670184 13 P04439 1 +E3 ubiquitin ligases ubiquitinate target proteins 0.2798645369038374 0.1618304966196291 0.8714393367514262 1.0 1.0 17 O75381,Q9BUN8 2 +Signaling by hippo 0.3620803630745955 0.1582358869662622 0.8742709262559936 1.0 1.0 6 Q07157,P62258 2 +Translation of sars cov 2 structural proteins 0.2778220633444446 0.1568900682469396 0.8753314873148683 1.0 1.0 19 Q10472,P48729,P27824,P04844,P04843,P46977,Q16706,P26572 8 +Formyl peptide receptors bind formyl peptides and many other ligands 0.5162004433974869 0.1522764354535069 0.8789689099444682 1.0 1.0 3 P05067 1 +Negative regulation of the pi3k akt network 0.2822733175066644 0.1447917052794771 0.8848753314389304 1.0 1.0 14 P30153,P30154 2 +Rhoc gtpase cycle 0.2539372076295706 0.1429165698208661 0.8863560720845689 1.0 1.0 36 P02786,Q8TAA9,P42167,Q14739,P27105,Q86VI3,Q07021,P49257,O75955,Q13190 10 +Ldl clearance 0.2862499441979046 0.1298033225782798 0.8967220341204374 1.0 1.0 13 P61916,Q6PIU2,P09496,O15118 4 +Dap12 signaling 0.3949224259520292 0.121620000912695 0.9031999726396612 1.0 1.0 4 P62993,P63000,P16885 3 +Scavenging by class a receptors 0.4937225681661229 0.1117043971300118 0.911057792748593 1.0 1.0 3 Q5KU26 1 +Meiotic synapsis 0.2692271844745734 0.107595530633999 0.9143165424473372 1.0 1.0 17 Q8WXH0,Q8WVM7,Q9UH99,P20700,P02545,O94901 6 +Regulation of plk1 activity at g2 m transition 0.2544665477978892 0.1072329282505897 0.9146041930633966 1.0 1.0 43 Q15154,P30153,Q9H6D7,P07900,P61163,Q13561,O75935,Q96CS2,P41208,O94927,P62258,Q14203,O95684,P53350 14 +Runx1 regulates expression of components of tight junctions 0.485335240366014 0.0981977261763046 0.9217752879878808 1.0 1.0 3 Q16625 1 +Chl1 interactions 0.4837891175641493 0.0922255763165634 0.926518817676085 1.0 1.0 2 P05556 1 +Vitamin c ascorbate metabolism 0.4835071891739684 0.0918399586909577 0.926825195756844 1.0 1.0 2 P00387 1 +Listeria monocytogenes entry into host cells 0.3021037498957955 0.0916569009667067 0.9269706412348752 1.0 1.0 8 P62993,P42566,Q92783,O14964,O60716 5 +Miro gtpase cycle 0.3553882259116163 0.0873725773874001 0.9303753660763394 1.0 1.0 5 Q8IWA4 1 +Rac1 gtpase cycle 0.2562574474133461 0.0800890571539608 0.936166425916286 1.0 1.0 47 P42166,P02786,Q86UP2,P50402,Q8TAA9,P42167,Q14185,O15498,Q14739,Q6IAA8,Q9H0H5,Q86VI3,Q14155,Q8N5V2,Q13576 15 +Intraflagellar transport 0.2665775567689376 0.0800571311026371 0.9361918176868896 1.0 1.0 15 Q9Y366,Q15643,Q92973 3 +Sars cov 2 infection 0.2477759977980363 0.0797057587008723 0.9364712792475918 1.0 1.0 26 Q8WUX9,Q10472,P48729,P27824,Q9UQN3,P04844,P04843,Q9Y3E7,P46977,Q16706,P26572,P14314 12 +Rnd3 gtpase cycle 0.2630407982985358 0.0782281909270283 0.9376465376087566 1.0 1.0 17 P38159,Q07065,O75976,Q8TAA9 4 +Ptk6 regulates cell cycle 0.4722300535663992 0.0772649531165862 0.9384127708937772 1.0 1.0 2 P11802 1 +Negative regulation of met activity 0.2968088110703079 0.0753307603342149 0.9399515477992206 1.0 1.0 8 P18031,P40818,P62993,P42566,P22681,Q92783,O14964 7 +Oncogenic mapk signaling 0.2470583772437862 0.0710147551198336 0.943386012252284 1.0 1.0 28 P51114,Q9NRY5,Q53H12,P51797,Q96PU8 5 +Pexophagy 0.4655950366610339 0.0698737056054103 0.9442941818503204 1.0 1.0 3 Q13501,P50542 2 +Class b 2 secretin family receptors 0.4629264166901705 0.0664604216732912 0.9470112669406834 1.0 1.0 2 Q9UBI6 1 +Rhoh gtpase cycle 0.2451382827687302 0.0661715896825965 0.9472412153346244 1.0 1.0 25 P27105,Q9Y6M7 2 +Synthesis of pips at the plasma membrane 0.2900161731281544 0.0609891418511919 0.9513678565057506 1.0 1.0 9 Q9BTU6 1 +Downregulation of erbb2 signaling 0.3253764971721895 0.0596743875820274 0.9524149711202036 1.0 1.0 6 Q16543 1 +Negative regulation of mapk pathway 0.2741743539046051 0.059499255202395 0.9525544586903556 1.0 1.0 12 P30154 1 +Raf activation 0.2808120993553432 0.053075687339883 0.957671602834024 1.0 1.0 11 P30154 1 +Recycling pathway of l1 0.2522000749882069 0.0508069031641729 0.9594793900539946 1.0 1.0 22 Q15418 1 +Toll like receptor cascades 0.243424865834253 0.050563102530462 0.9596736651113802 1.0 1.0 34 P05067,P30154,Q15418,P51812 4 +Caspase mediated cleavage of cytoskeletal proteins 0.2875586334531205 0.0486680487227592 0.9611838391146088 1.0 1.0 8 Q13813,P08670 2 +Retrograde neurotrophin signalling 0.2853107344632832 0.0472238639544583 0.9623348080515176 1.0 1.0 9 Q00610,P09496,Q96CW1,P50570,Q05193,P63010,P53680,O95782 8 +Ephrin signaling 0.3196022217077248 0.0467275876391518 0.9627303425997228 1.0 1.0 6 Q13177,Q14155,O00560 3 +Rhobtb gtpase cycle 0.2431335365523226 0.0456082167629472 0.9636225199593283 1.0 1.0 28 P07900,P07910,Q16543,Q8N684,Q9BT78,P08670,P38159,P12814,P78371 9 +Nef and signal transduction 0.4327600789399511 0.0384758249488688 0.9693083061041236 1.0 1.0 2 Q13177 1 +Disinhibition of snare formation 0.34583921015514 0.0349924800231166 0.9720857372748056 1.0 1.0 4 O00186,Q12846,P05771 3 +Egfr downregulation 0.274418046015859 0.0178501108631335 0.9857584284279528 1.0 1.0 9 P42566,Q9UBC2,Q92783,O14964,Q14155 5 +Role of second messengers in netrin 1 signaling 0.3946997462644578 0.0162530071323938 0.9870325474591886 1.0 1.0 2 Q00169 1 +Signaling by fgfr4 in disease 0.3946997462644548 0.0162530071323926 0.9870325474591894 1.0 1.0 2 P62993 1 +Met activates ptk2 signaling 0.3893431068508648 0.0140775901321936 0.9887680791690564 1.0 1.0 2 P05556 1 +Unwinding of dna 0.2728813559322089 0.0139879922693638 0.988839560882057 1.0 1.0 9 P25205,O75419,P33993,P49736,Q9BRX5,Q14566,P33991,Q9BRT9 8 +Tnfr1 induced proapoptotic signaling 0.384550324217655 0.0122988500128121 0.99018718484364 1.0 1.0 2 Q13546 1 +Trif mediated programmed cell death 0.384550324217655 0.0122988500128121 0.99018718484364 1.0 1.0 2 Q13546 1 +Tlr3 mediated ticam1 dependent programmed cell death 0.384550324217655 0.0122988500128121 0.99018718484364 1.0 1.0 2 Q13546 1 +Defective ripk1 mediated regulated necrosis 0.384550324217655 0.0122988500128121 0.99018718484364 1.0 1.0 2 Q13546 1 +Processing of intronless pre mrnas 0.2483290216921254 0.0112124844806234 0.9910539191949888 1.0 1.0 16 Q12996 1 +Downregulation of erbb2 erbb3 signaling 0.3775021144629309 0.0099516928275927 0.9920598289999416 1.0 1.0 2 P31751 1 +Assembly of collagen fibrils and other multimeric structures 0.3681984775866956 0.0073012531419203 0.9941744946015568 1.0 1.0 2 Q03001 1 +Type i hemidesmosome assembly 0.3681984775866956 0.0073012531419203 0.9941744946015568 1.0 1.0 2 Q03001 1 +Signaling by ntrk3 trkc 0.3948110547095383 0.0048353481198186 0.9961419654229504 1.0 1.0 3 P62993,Q8WX92 2 +Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0.3473357767127143 0.0029195134455141 0.9976705686059426 1.0 1.0 2 P29992 1 +Inlb mediated entry of listeria monocytogenes into host cell 0.2966412644651384 0.0022683178537385 0.9981901457575388 1.0 1.0 6 P62993,P42566,P22681,Q92783,O14964 5 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a2d70ef22b4c531ead2ba500dc4b446ca8afc10e --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases associated with surfactant metabolism", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pou5f1 oct4 sox2 nanog repress genes related to differentiation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trail signaling", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATF7IP", "ATG13", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATRX", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCKDK", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRAP", "BRCA1", "BRD2", "BRD4", "BSG", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CDS2", "CDX2", "CENPE", "CENPF", "CENPH", "CENPI", "CENPK", "CEP250", "CEP290", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLINT1", "CLNS1A", "CLSPN", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "COASY", "COG1", "COG3", "COG5", "COG7", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ9", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC27", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCD", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH1", "DDB1", "DDHD2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND4C", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFNB1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNBP1", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "IWS1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KCTD3", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KLC1", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC41", "LRRC8A", "LRRC8C", "LRRFIP1", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAD1L1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP2", "METTL1", "METTL3", "MFGE8", "MFN1", "MFN2", "MGAT1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO1E", "MYO5A", "MYO6", "NAA16", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEO1", "NFRKB", "NFS1", "NGEF", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NRBP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NT5C2", "NT5C3B", "NUB1", "NUBP2", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PVR", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RALGAPA1", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP36", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SBF1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX4", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE1", "SYNE2", "SYS1", "SYVN1", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAP1", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM11", "TMEM115", "TMEM30A", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TTC21B", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR4", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WLS", "WNK1", "WTAP", "XAB2", "XIAP", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10", "ZZZ3"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSL6", "ACTN1", "ACTN4", "ACTR1A", "ADD3", "AGK", "AGPAT5", "AKT2", "ALDH3A2", "ALG1", "ALYREF", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANKLE2", "ANO10", "ANXA1", "AP1M1", "AP2A1", "AP2B1", "AP2M1", "AP2S1", "APLP2", "APOO", "APOOL", "APP", "ARFGAP2", "ARFIP2", "ARHGEF7", "ARL1", "ARL6IP5", "ARV1", "ASAH1", "ATAD3B", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7A", "B4GALT1", "B4GAT1", "BAG6", "BAIAP2", "BCAP31", "BICD2", "BLOC1S1", "BNIP1", "BSG", "C19orf70", "C1QBP", "CALD1", "CALU", "CAMK1", "CANX", "CBL", "CCNB1", "CCT2", "CCZ1B", "CD47", "CDC16", "CDC27", "CDC37", "CDC42BPB", "CDC45", "CDIPT", "CDK1", "CDK4", "CERS1", "CERS2", "CERS5", "CETN2", "CHCHD3", "CHMP1A", "CHMP2B", "CHMP3", "CHMP7", "CHST14", "CKAP4", "CLCN3", "CLCN6", "CLCN7", "CLINT1", "CLTA", "CLTC", "COG1", "COG3", "COG5", "COG7", "COLEC12", "COPB2", "COPS3", "COPS4", "COPS5", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ9", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2L", "COX7C", "CPD", "CPNE8", "CPSF7", "CPT1A", "CPT2", "CSNK1A1", "CSTF3", "CTNND1", "CTSA", "CYB5B", "CYB5R3", "CYP51A1", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHFR", "DHRS7B", "DIABLO", "DNAJC11", "DNAJC3", "DNM1", "DNM2", "DOCK1", "DOLPP1", "DPAGT1", "DST", "EBP", "ECE1", "EHMT2", "EIF4B", "EMC3", "EMD", "ENDOD1", "EPB41L3", "EPS15", "EPS15L1", "ERAP1", "ERLIN2", "ERO1A", "ETFDH", "ETNK1", "EXOC2", "EXOC4", "EXOC7", "FADS1", "FAF2", "FAM114A2", "FAM49B", "FAR1", "FAR2", "FASN", "FDFT1", "FECH", "FGFR1OP", "FIS1", "FKBP14", "FKBP1A", "FLOT1", "FNBP1", "FUCA1", "FUCA2", "FXR1", "GAA", "GALNT1", "GALNT2", "GALNT4", "GBA", "GBF1", "GCC1", "GDE1", "GGCX", "GGT7", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLG1", "GM2A", "GNA11", "GNG12", "GNPAT", "GNS", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GRB2", "GSTA4", "GUSB", "GYS1", "HACD3", "HADH", "HAUS1", "HAUS4", "HAUS5", "HEXA", "HEXB", "HGS", "HLA-A", "HLA-B", "HLA-C", "HMGCR", "HMOX1", "HMOX2", "HNRNPC", "HNRNPK", "HS2ST1", "HSD17B12", "HSP90AA1", "HSP90B1", "ICMT", "IFT52", "IGF2R", "IMMT", "IQCB1", "IQGAP2", "IQGAP3", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF5B", "KPNA2", "KTN1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LBR", "LETM1", "LGALS3BP", "LGMN", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MAU2", "MBOAT7", "MCL1", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "MCUB", "MED24", "MFGE8", "MFN1", "MGAT1", "MIA2", "MIA3", "MICU1", "MICU2", "MIGA1", "MMGT1", "MOV10", "MPP2", "MPP7", "MSMO1", "MTCH1", "MTOR", "MTX1", "MYO5A", "NAA35", "NAGLU", "NCEH1", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF2", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NEDD4", "NEDD4L", "NEFL", "NELFB", "NGEF", "NNT", "NPC1", "NPC2", "NT5C2", "NUCB1", "NUP107", "NUP155", "NUP160", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP54", "NUP88", "NUP93", "NUPL2", "OCLN", "OS9", "OSBPL2", "OSBPL9", "OSTM1", "P3H1", "P4HA1", "P4HB", "PACSIN2", "PAK2", "PARL", "PCM1", "PCYOX1L", "PDK1", "PDP1", "PDS5A", "PECR", "PEX14", "PEX19", "PEX5", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PIGG", "PIGU", "PIK3C2A", "PIP4K2C", "PISD", "PITPNA", "PKMYT1", "PLA2G15", "PLCG2", "PLD3", "PLD6", "PLIN3", "PLK1", "PMPCA", "PNPLA8", "POLE4", "PON2", "PPFIA1", "PPP2R1A", "PPP2R1B", "PPT1", "PPT2", "PRCP", "PRELID1", "PRKAA2", "PRKAB1", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PSAP", "PSMB2", "PSMB4", "PSMB6", "PSMD11", "PSME2", "PSME3", "PTGES2", "PTPN1", "PTPRF", "PXMP2", "QKI", "RAB10", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB5B", "RAB7A", "RAB9A", "RABEPK", "RAC1", "RACGAP1", "RAD23B", "RALA", "RANGRF", "RBMX", "RDH13", "REPS1", "RFT1", "RINT1", "RIPK1", "RNASET2", "RPN1", "RPN2", "RPS6KA1", "RPS6KA3", "RRM2B", "RTN3", "SACM1L", "SAMM50", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCO1", "SCO2", "SCP2", "SDCBP", "SDHB", "SEC11A", "SEC23IP", "SEL1L", "SET", "SGPL1", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A15", "SLC25A17", "SLC25A26", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SNAP29", "SNAPIN", "SNX2", "SNX5", "SPCS2", "SPCS3", "SPHK2", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRPRB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STIM1", "STOM", "STOML2", "STT3A", "STX10", "STX18", "STX4", "STX5", "STX6", "STXBP3", "SUN1", "SUN2", "SURF4", "SYNE2", "SYS1", "SYVN1", "TAP1", "TFG", "TFRC", "TGOLN2", "TGS1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TMED10", "TMED2", "TMEM30A", "TMEM87A", "TMOD3", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM5", "TOMM6", "TOR1AIP1", "TPD52", "TPM1", "TPM4", "TPP1", "TPR", "TRA2B", "TRIM27", "TRIP11", "TSPO", "TTC26", "TTYH3", "TUBGCP2", "TUBGCP4", "TWNK", "UBE2S", "UGCG", "UGT8", "UNC119B", "UQCR10", "UQCRC2", "UQCRQ", "USP8", "VANGL1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS33B", "VPS51", "VPS52", "WAPL", "WFS1", "WLS", "XRCC6", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]} \ No newline at end of file diff --git a/msigdb_wp/advanced/idx2term.json b/msigdb_wp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b8708e448aa0932c6e2369dfd00ccc5154001ba0 --- /dev/null +++ b/msigdb_wp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Sphingolipid metabolism integrated pathway", "1": "Sphingolipid metabolism in senescence", "2": "Mitochondrial complex iv assembly", "3": "Electron transport chain oxphos system in mitochondria", "4": "Sphingolipid metabolism overview", "5": "Sphingolipid pathway", "6": "Metabolism of spingolipids in er and golgi apparatus", "7": "Ferroptosis", "8": "Metapathway biotransformation phase i and ii", "9": "Camkk2 pathway"} \ No newline at end of file diff --git a/msigdb_wp/advanced/plot_0.png b/msigdb_wp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7d99a4ce9310b4979e674ef4004fe9201219b4b5 --- /dev/null +++ b/msigdb_wp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:07197cd20630485e8526edaf2f9bb6013ddebed21716785fac78cdbc051a8d36 +size 195234 diff --git a/msigdb_wp/advanced/plot_1.png b/msigdb_wp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..44ee0438bada27e5543507c9a058650854d96df5 --- /dev/null +++ b/msigdb_wp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed1d130ad11e8c259c6588cc16395240e356c8c41f9d759fbf387f1f027e370b +size 201101 diff --git a/msigdb_wp/advanced/plot_2.png b/msigdb_wp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0390a5669226e61cd500cb6b07255006f9158d92 --- /dev/null +++ b/msigdb_wp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3849c26e009b9d10081da62d8ece0c685a955e58e07f0ea3fe5d8e00227768c9 +size 192827 diff --git a/msigdb_wp/advanced/plot_3.png b/msigdb_wp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..a5dbf4409cc6e8187c45ac1a0ec0cf110f8780a7 --- /dev/null +++ b/msigdb_wp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7d1189d892ebb9ddbeb5bd59b3bac296d7828c050de9bcba95b0539bcdc935d +size 212792 diff --git a/msigdb_wp/advanced/plot_4.png b/msigdb_wp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..704ba6d0274608111858f86e05ae876e12e74565 --- /dev/null +++ b/msigdb_wp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27b90f1ffe9be6cc7b567100aa9803eb2c017bad814b72548cdf6c574c321a82 +size 195435 diff --git a/msigdb_wp/advanced/plot_5.png b/msigdb_wp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..5a7f5b8ddfcfcfd6caa0c11ff450f16ff83d56d4 --- /dev/null +++ b/msigdb_wp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8f311a4dfcd4caa5c73d78177404ddc4f7279242f15f4d03f3a04c5f933dba8 +size 193635 diff --git a/msigdb_wp/advanced/plot_6.png b/msigdb_wp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..f3ca92f0e64c3ce20eec2d31818630cb5897bc7e --- /dev/null +++ b/msigdb_wp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4df602f7092101101a8f372ab49fa2b53d68a0dad3c57466f49a709781700bd7 +size 192239 diff --git a/msigdb_wp/advanced/plot_7.png b/msigdb_wp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..03cd4fb707a31c89a663f08dac43a133c712e012 --- /dev/null +++ b/msigdb_wp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:419cb4f7f3ca88cb7a59497c2ed1ed4c4b7e59df324752c8a0871061ef907eaa +size 203056 diff --git a/msigdb_wp/advanced/plot_8.png b/msigdb_wp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..abc8e7f1d6a833484ca1bb8d5a34dbd8a89932f3 --- /dev/null +++ b/msigdb_wp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bca4678b9a03367aa250d27c1d2993d1f1346c489862b4ac899cfe30e99bc0f4 +size 205961 diff --git a/msigdb_wp/advanced/plot_9.png b/msigdb_wp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..cfe6bbcfd2012b6ec0d9129f0eba3dc0dfaffea3 --- /dev/null +++ b/msigdb_wp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:544f787dfeaa0fd3543252b3b602d56fb6f8bcde3825fb69ee09806720219124 +size 198561 diff --git a/msigdb_wp/basic/idx2term.json b/msigdb_wp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4fe9a952a9b93f99052da815f6b75266252489b4 --- /dev/null +++ b/msigdb_wp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Sphingolipid metabolism integrated pathway", "1": "Sphingolipid metabolism in senescence", "2": "Mitochondrial complex iv assembly", "3": "Electron transport chain oxphos system in mitochondria", "4": "Sphingolipid metabolism overview", "5": "Sphingolipid pathway", "6": "Metabolism of spingolipids in er and golgi apparatus", "7": "Ferroptosis", "8": "Metapathway biotransformation phase i and ii", "9": "Camkk2 pathway", "10": "Overlap between signal transduction pathways contributing to lmna laminopathies", "11": "Oxidative phosphorylation", "12": "Mitochondrial complex i assembly model oxphos system", "13": "Cholesterol metabolism with bloch and kandutschrussell pathways", "14": "Vitamin d receptor pathway", "15": "Nonalcoholic fatty liver disease", "16": "Influence of laminopathies on wnt signaling", "17": "Type i collagen synthesis in the context of osteogenesis imperfecta", "18": "Allograft rejection", "19": "Intracellular trafficking proteins involved in cmt neuropathy", "20": "Cholesterol biosynthesis pathway", "21": "Cohesin complex cornelia de lange syndrome", "22": "Nephrotic syndrome", "23": "Arrhythmogenic right ventricular cardiomyopathy", "24": "Adipogenesis", "25": "7oxoc and 7betahc pathways", "26": "Proximal tubule transport", "27": "Glycerophospholipid biosynthetic pathway", "28": "Thermogenesis", "29": "Angiopoietinlike protein 8 regulatory pathway", "30": "Envelope proteins and their potential roles in edmd physiopathology", "31": "Calcium regulation in cardiac cells", "32": "Oxysterols derived from cholesterol", "33": "Nuclear receptors metapathway", "34": "Mecp2 and associated rett syndrome"} \ No newline at end of file diff --git a/msigdb_wp/basic/plot_0.png b/msigdb_wp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5b2c32f4ddcd51da9fa6ce8ceb59d20d14f81eeb --- /dev/null +++ b/msigdb_wp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:82d7e9a7ce7fa2ad20c1a09a8f060dcbfe7d5c329bdc2cd585421bd713662a2b +size 151320 diff --git a/msigdb_wp/basic/plot_1.png b/msigdb_wp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..74f6fdd182a5e5351d904e7611d67f9a243093c2 --- /dev/null +++ b/msigdb_wp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f60513aa8c4f0d6c004ac1ad25cf6885394918a9156dbeecbbe5e7d219f95a43 +size 149337 diff --git a/msigdb_wp/basic/plot_10.png b/msigdb_wp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..f6361de660a531cc6b4ee5ea4e28d433b262c0d6 --- /dev/null +++ b/msigdb_wp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d0cb7ff059bb84c5b66b13d887b52ea13b29db5f6321740a0154bd70d38f81f2 +size 143587 diff --git a/msigdb_wp/basic/plot_11.png b/msigdb_wp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..9dea22556a49f9567d30e5562cae6c086ec97bd1 --- /dev/null +++ b/msigdb_wp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d6f61d6f7b419abcc3845654750f93dbabcbca0358320aa3c66cb270ec57075a +size 139088 diff --git a/msigdb_wp/basic/plot_12.png b/msigdb_wp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..8d74a705df820075630019013abcdc21e5746c3a --- /dev/null +++ b/msigdb_wp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ab1411712b03cbafa3d9313c235ba530c19f189605e44c39ccbe02b4f0dbcf0 +size 144840 diff --git a/msigdb_wp/basic/plot_13.png b/msigdb_wp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..c50bc2c4fe438c8d167c431c236e24bd9b7bd76b --- /dev/null +++ b/msigdb_wp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3069562d315fa1aee9323c9d6f048b98cebfa6804b95e9a8ee1de48b96ac591b +size 149933 diff --git a/msigdb_wp/basic/plot_14.png b/msigdb_wp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..3738c76f48fdefe97f8b6e202d7e93af8a457744 --- /dev/null +++ b/msigdb_wp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fec2f407f94c5931f3550cf331bcb2c03fed8b0581933d5e4d8e86ea6a46f64 +size 138588 diff --git a/msigdb_wp/basic/plot_15.png b/msigdb_wp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..1637b8f9bcbe8d2f3ee6fe3474adca3fdf9e8cfb --- /dev/null +++ b/msigdb_wp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c63803e6a890e6c77520b36f1d467401cce8127edf956d0dd5fdd201493933a6 +size 146662 diff --git a/msigdb_wp/basic/plot_16.png b/msigdb_wp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..22c052a60e0e6730f48de531344ba3cf087bcfe3 --- /dev/null +++ b/msigdb_wp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d3f06beb86718df329c8ea466b793feeea4f6883d8e63481436db95d5566e06 +size 146204 diff --git a/msigdb_wp/basic/plot_17.png b/msigdb_wp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..e4026642fb86bd1458a1f7715622144f53f15d11 --- /dev/null +++ b/msigdb_wp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b582d542ec5da67f0a6df1e8d78fb04287ec919d45085d1081189b9715df177b +size 140780 diff --git a/msigdb_wp/basic/plot_18.png b/msigdb_wp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..76f7880a6bad8026b52231379b297f9c49bda4d4 --- /dev/null +++ b/msigdb_wp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc258c00cb29efda316e23bd561ff79fe138464250b6610688eb4156f2224a1b +size 130259 diff --git a/msigdb_wp/basic/plot_19.png b/msigdb_wp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..b5a8d0bf1cef0e914b5f047f4ccca5376e3e1cfd --- /dev/null +++ b/msigdb_wp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e14b9c59546c2e5544fa6a2e0171ff51857fc60d9da76ec6af836f8423f6d7ee +size 137669 diff --git a/msigdb_wp/basic/plot_2.png b/msigdb_wp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9800bae4974842656d91cde2eb40c12b4fca7e3a --- /dev/null +++ b/msigdb_wp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df34fac8368acea9f6f2466b6b9138eb55973fee222d86b39c92e9c5e7f50d28 +size 147543 diff --git a/msigdb_wp/basic/plot_20.png b/msigdb_wp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..4ec17a550633751060648f56f2f208946ef87398 --- /dev/null +++ b/msigdb_wp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:944c927d24dba27abc0592172af20c7fa784449b54cd9a62d0ba11e55ce64449 +size 141476 diff --git a/msigdb_wp/basic/plot_21.png b/msigdb_wp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..49c75cfd70693a09da33cf0c97f5cd7727cf33c6 --- /dev/null +++ b/msigdb_wp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f27f2fa0e477acf80886c23de59b9d1059ec4db1c28153eec637acc113e27dbc +size 151772 diff --git a/msigdb_wp/basic/plot_22.png b/msigdb_wp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..2f0c911a28137701c6678b9056a5ef3239738519 --- /dev/null +++ b/msigdb_wp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de670c21bc802209d254735af37e4b88a6a1b01beb87f1392fbabb4914aacd81 +size 146907 diff --git a/msigdb_wp/basic/plot_23.png b/msigdb_wp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..ac22d8c909d8b305c4c42493c9d2c9b2a8735406 --- /dev/null +++ b/msigdb_wp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3f927334437ae03ae70d79219c40e4979c1959f3c5d80f081784d73e35ad9a5a +size 148135 diff --git a/msigdb_wp/basic/plot_24.png b/msigdb_wp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..4af5cabce5ba67b92dc73f0835a02471b3fe0c9c --- /dev/null +++ b/msigdb_wp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fdcf10a0ef6b8ed7a4423039802d9248e3aa408ce347f3881336501c35728c60 +size 148768 diff --git a/msigdb_wp/basic/plot_25.png b/msigdb_wp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..9d14c350a5f05f7317c53d23ee28550a88014fed --- /dev/null +++ b/msigdb_wp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:acb7a30d169599eea6a3b54522fdf8664206b92a48c9947b6bd2e8204660f13f +size 152679 diff --git a/msigdb_wp/basic/plot_26.png b/msigdb_wp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..a05cb50c12dbe83ec1e47d6eda21235acf0f5c59 --- /dev/null +++ b/msigdb_wp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:134bb8000bbae9a5670c69e747dfed08c49d7e64ebace02793da65accaa1decd +size 141137 diff --git a/msigdb_wp/basic/plot_27.png b/msigdb_wp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..41387850b762f6717b4628ac2b1c8a47374308eb --- /dev/null +++ b/msigdb_wp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2dc0086f22606d3d6b627599a18ec3a6db1f891bc632d6fbcb0c3f3140d70853 +size 149219 diff --git a/msigdb_wp/basic/plot_28.png b/msigdb_wp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..6e01ca9cd94a072084d5358e54d3ae90b4c22df3 --- /dev/null +++ b/msigdb_wp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df09d180d0c2a35ee706823c06d812006730683e5f3c298d0ae986389a88b8c5 +size 147725 diff --git a/msigdb_wp/basic/plot_29.png b/msigdb_wp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..4041619698fda21e6841d4baa294efb7f17cbd9a --- /dev/null +++ b/msigdb_wp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:159c6814aa2f702f5228a6b46971f855b0d4dd515715ac6cc6fc1c76779b6a10 +size 156900 diff --git a/msigdb_wp/basic/plot_3.png b/msigdb_wp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..68b82c5d158f4cb1f58e0706c95a16bcbb0bf87b --- /dev/null +++ b/msigdb_wp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d0946e9b6acc342beb8b4aaa2fc894e4cde82993ec301274b2811457648b6bb +size 149711 diff --git a/msigdb_wp/basic/plot_30.png b/msigdb_wp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..40306b2a50ddfe65a8ea9a3041ea10538403c183 --- /dev/null +++ b/msigdb_wp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b31f8558013c1b49068e35a592fbaaa60e815f246b4709d64ad7a678797fd3f7 +size 154731 diff --git a/msigdb_wp/basic/plot_31.png b/msigdb_wp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..8710759e9f538480e68987da3a7265c8b92d2106 --- /dev/null +++ b/msigdb_wp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fcbba7cb2fb85be052e2a54fd2714aead36a9d83bb0b7bb561563d2b4898ae59 +size 155653 diff --git a/msigdb_wp/basic/plot_32.png b/msigdb_wp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..5aa381d8fb856c38ee29f73269ed6a2d734fe7db --- /dev/null +++ b/msigdb_wp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:303c073a87d5f745e09c8e91ce89385ec3e953cb320b096f272028b6ed13b8af +size 150288 diff --git a/msigdb_wp/basic/plot_33.png b/msigdb_wp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..f874a73cb539c16782a1516a7d226df56c01b67b --- /dev/null +++ b/msigdb_wp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8842498a645dd675da4a2fdfac5f4f725fe2a015f9c2c074f4176e1a75ba8b98 +size 155149 diff --git a/msigdb_wp/basic/plot_34.png b/msigdb_wp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..a90bf14567c5b5d36c7c13095801bed40741e198 --- /dev/null +++ b/msigdb_wp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:49a7185387ae3e720da9e57b3b35af2d2bc61d58f8eeebb94e23378f3e23d74b +size 161376 diff --git a/msigdb_wp/basic/plot_4.png b/msigdb_wp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..6e553ed036a785f9767f2f9270b4132149749e85 --- /dev/null +++ b/msigdb_wp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99ed92c4abc3f86b48200a265a7b6c993ef1b896c499a3924d92d1494ccad35f +size 149834 diff --git a/msigdb_wp/basic/plot_5.png b/msigdb_wp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..0c1e89b442ef7d832437b10c75136c3c99224389 --- /dev/null +++ b/msigdb_wp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aead32b294fc268db4f6f222c6b2541c5dfa7da85f8963b07b37fce959bdf21a +size 140445 diff --git a/msigdb_wp/basic/plot_6.png b/msigdb_wp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..4b8d12dd4b5b9a279ac7a0e6bc33ac18922e7d79 --- /dev/null +++ b/msigdb_wp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:543087e80f456f527ec4cdf6f5f5508112278a7469fbc0d1c65225ae7b1198d8 +size 146983 diff --git a/msigdb_wp/basic/plot_7.png b/msigdb_wp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..3d608aa9b6e509b6816dfebe4f66ed6d79beac7d --- /dev/null +++ b/msigdb_wp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce04d133277c7b3d97749c5261076d41c90ae4b152a5fb9e774ed55b6db991b3 +size 139093 diff --git a/msigdb_wp/basic/plot_8.png b/msigdb_wp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..eceab0d52a37e3b7fd36643b8d1fc5f6f119091c --- /dev/null +++ b/msigdb_wp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7c0ea122c43a25a9aa66eb3c36c18d7df1dd81222de983f1e5e9a73889ff090 +size 141778 diff --git a/msigdb_wp/basic/plot_9.png b/msigdb_wp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..f08541ec1a2beae4fd9883d69087f853fbce48b3 --- /dev/null +++ b/msigdb_wp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:adaefc3dbcf56ca350762684228f85c25404572fa4633acd97e81453f89ee756 +size 131841 diff --git a/msigdb_wp/consensus.joblib b/msigdb_wp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..928ad8c830698c6f4893b7e78d886f1967a948c2 --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2f205a161d1705d0054e6137e8e642f53a659012c6b177a59a88dd684d0f23a +size 123409 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..467ed52b1293fa02a2d3d129afe731fa6afa97ff --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,21 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Sphingolipid metabolism integrated pathway 9 11 3.087385780074306 0.0020192535506602 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 7.498622024646661e-08 0.0858288536093336 0.1677870330809631 0.0009779431698101 8.47615097503614e-08 +Sphingolipid metabolism in senescence 7 14 3.0774529771606742 0.0020877777505678 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 6.844909444718143e-06 0.1029565435856987 0.1993869387044997 0.0020705519968491 7.6029662263182175e-06 +Mitochondrial complex iv assembly 10 13 3.0446755453662084 0.0023293144878695 4.645631067961165 11.985436893203884 1.036764412652062 0.2236438909453165 2.399566170297607 1.9080263664188637 1.5325215618909758 0.2795558816325345 0.0009718805853873 0.1484538203623246 0.0041517217414646 0.0012549484261259 0.0010565154778331 +Electron transport chain oxphos system in mitochondria 26 54 2.9922150388217825 0.0027696109841828 17.57766990291262 50.45631067961165 1.00621396752225 0.3125021459260491 7.648293572467493 4.538458527560961 1.9412236823915887 0.3642771965747766 7.706192774774378e-09 6.413358808765925e-05 2.4073978163943948e-06 1.8108119815621985e-06 9.8112350841743e-09 +Sphingolipid metabolism overview 8 10 2.905740888465956 0.0036638471068064 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 4.382901822134934e-07 0.0771453392642774 0.1515272625734178 0.00062382482254 4.886716881718799e-07 +Sphingolipid pathway 9 12 2.683497363112255 0.0072856549750328 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 3.547454222803857e-07 0.0987043131013681 0.191600110602388 0.0001505310959671 4.002217138994603e-07 +Metabolism of spingolipids in er and golgi apparatus 6 7 2.6189905650440526 0.0088190386654283 2.1432038834951457 4.12378640776699 1.255170581651192 0.2109312980793922 1.3711229283492827 1.3022449745711573 1.2018683368625842 0.2544377197345568 0.0002321391353102 1.0 1.0 0.003355333516566 0.0002481332774246 +Oxidation by cytochrome p450 3 6 2.4065351749734667 0.0161046530554027 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 0.0026425445039808 0.0016377422378922 0.0066572828402184 0.003355333516566 0.0027834726260547 +Mitochondrial complex iii assembly 2 9 2.3966332276869764 0.0165464770051055 3.3106796116504853 9.259708737864075 1.0287385637679851 0.2644162586394033 1.7668969355473032 1.3138647920792297 1.192785152283574 0.2813694304742245 0.0324301480805536 0.0021914548918381 0.0088504827764808 0.0051503840765812 0.0336357980244025 +Ferroptosis 10 26 2.297119873612408 0.0216119323554697 6.247572815533981 23.589805825242717 0.9586016481897424 0.3324276931898122 2.8577723913591164 2.1450310521583007 1.2134257594151 0.3161491716459103 0.0027258361045354 0.0238997911322505 0.08610744549237 0.0075944976014186 0.0029760556157756 +Cholesterol biosynthesis with skeletal dysplasias 4 7 2.2863025490126634 0.0222365648683158 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 4.820322937886373e-06 1.0 1.0 0.0004573905935078 5.170697431969709e-06 +Proteoglycan biosynthesis 2 5 2.2324060013742573 0.0255881415322953 1.966019417475728 4.298543689320389 1.0185999272660573 0.2724845511957944 1.255593573941796 1.5981475367005755 1.1753810774067486 0.2740057085210428 0.0324301480805536 1.0 1.0 0.0051503840765812 0.0336357980244025 +Glycosaminoglycan degradation 4 6 2.1576906782039376 0.0309518891961242 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 0.0001486934237484 1.0 1.0 0.0328731354880699 0.0001590313802548 +Statin inhibition of cholesterol production 4 7 2.1008954026514868 0.035650149086527 2.0315533980582523 5.029126213592233 1.044092701346018 0.2144191485801186 1.2890406286437517 1.2084356467042294 1.2621579412510306 0.2395890160394713 0.0268788760081442 1.0 1.0 0.290751966651369 0.0278921605814954 +Familial partial lipodystrophy fpld 4 8 2.042033806360193 0.0411481780431166 2.7354368932038833 7.351941747572815 1.0487704575374006 0.2220749325398317 1.64741826657551 0.7567951823729889 1.2080189526980365 0.2461617416466816 0.0768164760449794 1.0 0.0170518298819148 0.090818300458346 0.0794376465838621 +Metapathway biotransformation phase i and ii 5 24 2.039514883195429 0.0413986673655233 5.674757281553398 21.74757281553398 1.0367643596879972 0.3247805075973627 2.26648088910968 1.8784337960788755 0.9302956939670612 0.2816826074355951 0.0666748062072547 0.0323055044295255 0.1132051672598368 0.0031898046957766 0.0704094801772502 +Camkk2 pathway 6 15 2.019386838282747 0.0434470284550518 2.6820388349514563 11.24514563106796 0.5445336169793533 0.5237007471512424 1.941715715758088 2.1396852885719895 0.7192156127901149 0.2856325720468268 0.0083546496185296 0.1197698958477507 0.2297987482657219 0.1383652025719425 0.0015869747860804 +Degradation pathway of sphingolipids including diseases 3 6 2.0090478374325755 0.044532060754977 3.645631067961165 6.432038834951456 0.0687547082162972 0.1728701573933007 1.3368036576958324 0.5554170290527195 1.9109030412897592 0.2451148181788838 0.0005429904047299 0.04159641685533 0.0832836732680532 0.0188064524051028 0.0005732271800539 +Overlap between signal transduction pathways contributing to lmna laminopathies 7 16 1.96933366353142 0.0489147879083788 4.927184466019417 14.766990291262136 1.2077866030529698 0.2877996039599693 1.943257907759383 1.4611731122572065 0.935661776029738 0.2919054664837305 0.0628856072356096 1.0 0.0693457394610891 0.2978006616879862 0.0660317196551079 +Oxidative phosphorylation 10 33 1.968889040590428 0.0489658343333403 10.094660194174756 30.308252427184467 0.4493106572238387 0.4094278581483465 4.631390429635194 3.3340884045985604 1.35936739882113 0.3321380007425058 0.0001506806965379 0.0247821522094747 0.0135419734012732 0.0015231541907095 0.0001692953162957 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..be4355f0bd77f3648d8e2da2537ac04e560cb5e4 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 608, + "title": "Average number of proteins per term", + "value": 11.761513157894736 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d2ba95da8d2d126d3e12b495a0341c120263fbff --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..95ab9733ff659917ede673657d545744420d3c9b --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,129 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sphingolipid metabolism integrated pathway 0.8336521459891557 3.087385780074306 0.0020192535506602 0.7073995799890067 0.1089402468172835 11 P27544,Q06136,Q96G23,O95470,Q16739,Q13510,Q16880,Q8N5B7,O15269 9 +Sphingolipid metabolism in senescence 0.7409942797492174 3.0774529771606742 0.0020877777505678 0.7193637127863013 0.1089402468172835 14 Q06136,Q96G23,P04062,Q13510,Q16739,O15269,P16278 7 +Mitochondrial complex iv assembly 0.7632298094795891 3.0446755453662084 0.0023293144878695 0.7577718404818681 0.1089402468172835 13 Q9Y2R0,P20674,Q9Y6N1,P15954,Q96I36,Q8N8Q8,P00403,P13073,Q7KZN9,P14406 10 +Electron transport chain oxphos system in mitochondria 0.5435596483925904 2.9922150388217825 0.0027696109841828 0.8147890252241758 0.1122615652255438 54 Q9UDW1,O75880,Q9Y6N1,O14949,P00846,O43676,O95139,P56385,O14548,P15954,O75964,P00403,P12236,P21912,P06576,P05141,P03886,P13073,Q9Y6M9,P51970,Q9UII2,P14406,O96000,P12235,Q7KZN9,P24539 26 +Sphingolipid metabolism overview 0.8312190313573408 2.9057408884659557 0.0036638471068064 0.8926552717460422 0.1311161576039895 10 P27544,Q06136,Q96G23,O95470,Q16739,Q13510,Q16880,O15269 8 +Sphingolipid pathway 0.7245786778115287 2.683497363112255 0.0072856549750328 0.9882733773993332 0.1478675342633888 12 Q06136,Q96G23,O95470,P04062,Q16739,Q13510,Q16880,Q8N5B7,O15269 9 +Metabolism of spingolipids in er and golgi apparatus 0.8382269904008901 2.6189905650440526 0.0088190386654283 0.9954186390724408 0.1577051620170712 7 Q06136,O95470,Q10472,Q16739,Q16880,Q9NRA0 6 +Oxidation by cytochrome p450 0.858405287747796 2.4065351749734667 0.0161046530554027 0.999948366058916 0.2095887087313374 6 O43169,Q16850,Q6UW02 3 +Mitochondrial complex iii assembly 0.7360145492468391 2.3966332276869764 0.0165464770051055 0.9999607052092468 0.2095887087313374 9 Q9UDW1,O14949 2 +Ferroptosis 0.4994762834883092 2.2971198736124077 0.0216119323554697 0.9999982987127788 0.2305272784583441 26 P16435,Q9NZ45,P45880,P09601,Q15043,P04035,Q96QD8,Q9Y277,Q9UKU0,P37268 10 +Cholesterol biosynthesis with skeletal dysplasias 0.7684508817998055 2.2863025490126634 0.0222365648683158 0.9999988461598776 0.2323894389088556 7 Q15125,Q15392,Q16850,Q14739 4 +Proteoglycan biosynthesis 0.8749217532676075 2.2324060013742573 0.0255881415322953 0.999999856953623 0.2325879783305822 5 Q8TB61,Q9NX62 2 +Glycosaminoglycan degradation 0.8029627477619392 2.1576906782039376 0.0309518891961242 0.9999999950115428 0.2412660080928658 6 P16278,P54802,P15586,P06865 4 +Statin inhibition of cholesterol production 0.7306870030276555 2.1008954026514868 0.035650149086527 0.9999999997401948 0.2626994104664452 7 Q8WTV0,P37268,Q14534,P04035 4 +Familial partial lipodystrophy fpld 0.6805729123032772 2.042033806360193 0.0411481780431166 0.9999999999919664 0.2765976896509691 8 O75844,O60725,Q03252,P20700 4 +Metapathway biotransformation phase i and ii 0.4832123395559774 2.039514883195429 0.0413986673655233 0.9999999999931464 0.2765976896509691 24 P21964,Q8NCH0,O15217,Q7LGA3,Q6UW02 5 +Camkk2 pathway 0.5615109281354353 2.019386838282747 0.0434470284550518 0.9999999999981332 0.2838685864504745 15 Q9Y3D6,Q13586,P09601,O00429,O76024,P42345 6 +Degradation pathway of sphingolipids including diseases 0.7705467670499309 2.0090478374325755 0.044532060754977 0.9999999999990636 0.2838685864504745 6 P06280,P16278,P17900 3 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5451186941342034 1.96933366353142 0.0489147879083788 0.9999999999999428 0.2918747772026561 16 O75844,P55209,P50402,P48729,P42167,P02545,O60725 7 +Oxidative phosphorylation 0.4439287027482241 1.968889040590428 0.0489658343333403 0.9999999999999446 0.2918747772026561 33 O95139,P56385,Q86Y39,O75964,P03886,Q15904,P00846,P06576,O96000,P24539 10 +Mitochondrial complex i assembly model oxphos system 0.4547586152481135 1.9429772785204535 0.0520189036892193 0.999999999999992 0.3029674132426017 28 O95139,Q96CU9,P03886,Q9P0J0,Q9NPL8,O43676,Q9BUB7 7 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4688029371935551 1.9162063756588736 0.0553388321665808 0.9999999999999992 0.3029674132426017 24 Q16850,O60427,O75845,P49327,Q14534,P04035,Q15125,Q14739,Q15800,Q15392,P37268 11 +Vitamin d receptor pathway 0.5343356316305841 1.835043145936969 0.0664992968329294 1.0 0.3110120959570853 15 P33897,Q92604,Q96KA5,P20020,P08183,P09493 6 +Nonalcoholic fatty liver disease 0.4269608224842101 1.8031190926815717 0.0713695132692744 1.0 0.327658553528989 54 O95139,Q9UDW1,P54619,P14406,Q86Y39,O14548,P15954,O14949,P49327,P00403,Q9P0J0,P21912,P13073,Q9Y6M9,O43676,P51970,O96000 17 +Influence of laminopathies on wnt signaling 0.5817316553064855 1.699288295690388 0.0892648767904529 1.0 0.3667097641121309 11 O75844,P50402,P02545,O60725,Q5JTV8 5 +Ccl18 signaling pathway 0.6149817539936315 1.6889641514793658 0.0912263000687452 1.0 0.3719459903396925 8 P08670,Q86UE4,P00403 3 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.5562407397047281 1.686170360223818 0.0917629910377531 1.0 0.3719459903396925 12 P07237,Q5JRA6,Q32P28,Q96AY3,P13674 5 +Acquired partial lipodystrophy barraquersimons syndrome 0.7441613717580283 1.6605821091742323 0.0967974046052146 1.0 0.3846589673200688 5 O60725,Q03252,P20700 3 +Allograft rejection 0.5335043021144787 1.5439508564550264 0.122600238402261 1.0 0.4395796438871963 12 P01889,P10321,Q9BY49,P04439,P08183,P08670 6 +Irinotecan pathway 0.9120383422610596 1.539265340574953 0.1237395317099256 1.0 0.4395796438871963 2 P33527 1 +Progeriaassociated lipodystrophy 0.5718497037404217 1.5140279140755868 0.1300187598678128 1.0 0.4397037193695409 10 O75844,O60725,Q03252,P20700 4 +Intracellular trafficking proteins involved in cmt neuropathy 0.5445340511085439 1.4772103704436277 0.1396192547797752 1.0 0.4638716224377231 11 P07196,Q8TB36,O95140,P50570,Q9NR77,P20338,Q9UI14 7 +Striated muscle contraction pathway 0.6474049652635072 1.4254050152035882 0.1540401591835039 1.0 0.4929285093872124 6 P09493,P08670 2 +Cholesterol biosynthesis pathway 0.506859554206512 1.3756373759996765 0.1689339290839266 1.0 0.5187466105203405 12 Q16850,O75845,Q14534,P04035,Q15800 5 +Zinc homeostasis 0.8793006204173657 1.3690354181049131 0.1709882039324877 1.0 0.522416221060063 3 Q8TAD4,Q8N1S5 2 +Cohesin complex cornelia de lange syndrome 0.4510995220104475 1.3528006320355008 0.176119330802114 1.0 0.5327390702869917 17 Q9UQE7,P30153,Q29RF7,Q7Z5K2,Q14674,Q8N3U4,P30154,Q9Y6X3,P53350 9 +15q112 copy number variation syndrome 0.6712547639163093 1.3306215458622823 0.1833135693575585 1.0 0.5433219512995969 5 Q06787,Q9UGJ1 2 +Familial hyperlipidemia type 4 0.713638314628811 1.3084314888393558 0.1907269980533694 1.0 0.5548421761552566 4 P49327,Q9UBV2 2 +Triacylglyceride synthesis 0.665086848528867 1.3025003638584405 0.1927453936612304 1.0 0.5553440910994069 5 Q9NUQ2,Q9HCL2 2 +Spinal cord injury 0.4117207185754538 1.2758156344128004 0.2020206995036129 1.0 0.5614928475345992 22 P08670,P62942,Q9NQC3 3 +Vitamin d metabolism 0.8412990749783271 1.2202966289150805 0.2223524472789158 1.0 0.5858618068653147 3 P04062 1 +1q211 copy number variation syndrome 0.4967477881779781 1.1880574640601669 0.234810770965248 1.0 0.5948539531119618 11 P54619,Q16625,Q9NPH0,Q07157 4 +Amyotrophic lateral sclerosis als 0.506330025305464 1.135305709740485 0.2562472507148612 1.0 0.6205201291782335 10 P07197,Q9BUN8 2 +Drug induction of bile acid pathway 0.8119537637440087 1.1229271475707292 0.2614684366506496 1.0 0.6234227822886195 2 P08183 1 +Aspirin and mirnas 0.8119537637440062 1.1229271475707177 0.2614684366506545 1.0 0.6234227822886195 2 Q15118 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.5816253035002286 1.1057102250738504 0.2688519628656436 1.0 0.6311273877309317 6 P09601,O15439 2 +Vitamin dsensitive calcium signaling in depression 0.5356574845202859 1.0929541044834674 0.2744139512065842 1.0 0.6392478250329624 7 P20020,P23634 2 +Nephrotic syndrome 0.4160212322957766 1.0451595953123023 0.2959492141333613 1.0 0.6510609007872952 16 O75844,O43707,Q96D53,Q9BT22,Q14108 5 +Urea cycle and related diseases 0.780659712433025 0.994919921618158 0.3197752129153668 1.0 0.6758069621512949 2 Q9Y619 1 +Pkcgamma calcium signaling pathway in ataxia 0.6337354087976106 0.9644133935505996 0.3348387099366816 1.0 0.6970816300628951 4 Q15118 1 +Metabolism of alphalinolenic acid 0.7654355793628418 0.9334467727779932 0.3505893403936475 1.0 0.710527729864459 2 O60427 1 +Linoleic acid metabolism affected by coronavirus infection 0.7654355793628418 0.9334467727779932 0.3505893403936475 1.0 0.710527729864459 2 O60427 1 +Genes related to primary cilium development based on crispr 0.4044865528779111 0.9231637206255198 0.3559218919554281 1.0 0.7180468654829479 15 Q9Y366,Q96J42,Q10713,O95684 4 +Arrhythmogenic right ventricular cardiomyopathy 0.4213444865832028 0.9133285870971672 0.361069751698077 1.0 0.7219902792666792 13 P06756,O43707,P16615,P50402,P02545 5 +Orexin receptor pathway 0.382999313702021 0.8970784522028987 0.369677055861048 1.0 0.7250440321403782 19 Q9P0J1,O60313 2 +Hostpathogen interaction of human coronaviruses mapk signaling 0.4715374344982653 0.8903706869885141 0.3732668767493203 1.0 0.7250679267207245 8 Q15418 1 +Extracellular vesiclemediated signaling in recipient cells 0.753405402714139 0.8814143599047892 0.3780935881474077 1.0 0.7314712384448878 3 P42345 1 +Adipogenesis 0.3857335153673377 0.8658860360379056 0.3865526615203667 1.0 0.7344500568886968 17 O75844,Q9NZ45,P49327,P02545,P43490 5 +7oxoc and 7betahc pathways 0.4428863140784124 0.8622407225070202 0.3885550648497313 1.0 0.735954764575192 11 P61916,Q9Y305,Q15125,Q9UBM7,O14734,O15118,P22307 7 +Endothelin pathways 0.4533990718921343 0.8257329793245134 0.4089555798976461 1.0 0.7557598558594798 9 P42892,P00403 2 +Liver x receptor pathway 0.7189173949816807 0.7503818888138293 0.4530247356608523 1.0 0.8044885045925768 2 P49327 1 +Copper homeostasis 0.4365867562746008 0.7348913642921165 0.4624056581025542 1.0 0.8126590554207936 10 P05067,O75880,Q04656,Q9Y6N1 4 +Neuroinflammation 0.5381624069062674 0.729891201334322 0.4654566909515083 1.0 0.8132116899382675 5 P00403 1 +Proximal tubule transport 0.3997178032562045 0.6984475033598856 0.4848973774381933 1.0 0.8253628658879234 12 Q9Y5K8,P36543,P05026,P08183,O15439,P05023 6 +Glycerophospholipid biosynthetic pathway 0.4363433034334511 0.6977753267501627 0.4853177115846934 1.0 0.8253628658879234 8 O15228,O14735,Q9HCL2,Q9BTU6,O95674 5 +Riboflavin and coq disorders 0.4354079331388275 0.6927436941433122 0.488470413116179 1.0 0.8253628658879234 8 Q16134 1 +Nrf2 pathway 0.3279504707931123 0.6685678029749051 0.5037712168206738 1.0 0.8287683152688815 24 O15217,P09601,Q9H2J7 3 +Familial hyperlipidemia type 5 0.6909838378805212 0.6523423798697663 0.514180326345069 1.0 0.838127716937807 3 Q9UBV2 1 +Familial hyperlipidemia type 1 0.6909838378805212 0.6523423798697663 0.514180326345069 1.0 0.838127716937807 3 Q9UBV2 1 +Familial hyperlipidemia type 3 0.6810245719335968 0.6173321304769936 0.5370156780109774 1.0 0.8504280605910948 3 Q8WTV0 1 +Nuclear receptors in lipid metabolism and toxicity 0.6828305610374971 0.6153404773723357 0.5383298914281887 1.0 0.8504280605910948 2 P08183 1 +Glycerolipids and glycerophospholipids 0.4381165809216545 0.5894230984934442 0.5555774853153599 1.0 0.8567231594842716 7 Q9HBU6,Q9HCL2,Q9UG56 3 +Complement system in neuronal development and plasticity 0.3515211463632966 0.5859482202737705 0.5579103116102524 1.0 0.8567231594842716 16 Q5KU26,Q9NR28,P06756,Q08431 4 +Vitamin b12 metabolism 0.4131192290592467 0.5747422114853873 0.5654656548431598 1.0 0.8616619502371959 8 Q8WTV0 1 +Arachidonate epoxygenase epoxide hydrolase 0.6684522131378715 0.5637955279763144 0.5728932956372903 1.0 0.8636688696845712 2 P20674 1 +Thermogenesis 0.3054762814076793 0.5632021120510448 0.5732972648714885 1.0 0.8636688696845712 31 P51812,P23786,Q969G3,P50416,Q15418,P42345,Q9UKU0 7 +Bdnftrkb signaling 0.4080395534857309 0.5484429647343838 0.5833877819086717 1.0 0.8636688696845712 8 Q15418 1 +Nanomaterial induced apoptosis 0.4632942090990548 0.5469198353408493 0.5844338078351659 1.0 0.8636688696845712 6 Q9NR28 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.4289533680744967 0.5446823352516729 0.5859720161382733 1.0 0.8636688696845712 7 Q15118 1 +Target of rapamycin tor signaling 0.3487046110581973 0.5404651228845253 0.5888763072354053 1.0 0.8636688696845712 15 P42345,P62942,P04035 3 +Nocgmppkg mediated neuroprotection 0.4279023865995792 0.5395980175192847 0.589474284105654 1.0 0.8636688696845712 7 P07196 1 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.6594305046518211 0.5322233296820092 0.5945713266651462 1.0 0.8648310206038491 2 P08195 1 +Tyrobp causal network in microglia 0.4586133924624598 0.5262582415507476 0.5987087925926287 1.0 0.866702252134091 6 Q5T1M5,P61916,Q15418,O15439 4 +Kennedy pathway from sphingolipids 0.481289988552541 0.491076133943954 0.6233726007144056 1.0 0.8752612379893618 5 Q9HBU6,O95470 2 +Angiopoietinlike protein 8 regulatory pathway 0.2923897417215815 0.4716796044075947 0.6371554971891287 1.0 0.8826092931551095 34 P51812,P46108,O14654,P54619,Q9UPT5,P49327,Q15418,Q9Y6R4,O95819,O75955,P42345 11 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.3875111857546946 0.469052368888576 0.6390322039213927 1.0 0.8826092931551095 9 P61020,P31943 2 +Pregnane x receptor pathway 0.4753360388954296 0.467444250552299 0.6401820695417817 1.0 0.8826092931551095 5 O15439,P08183 2 +Congenital generalized lipodystrophy cgl 0.6388497321680351 0.4626733011394027 0.6435985584715431 1.0 0.8853120442323489 2 P31751 1 +P53 transcriptional gene network 0.3819812736385918 0.4410459493895698 0.6591797322329855 1.0 0.8958069538959246 9 Q7LG56,Q9NQ88,P49327 3 +Omega3 omega6 fatty acid synthesis 0.4042835198559041 0.4283200881754793 0.6684180956462678 1.0 0.8958069538959246 7 O95864,O60427,Q15067 3 +Mitochondrial immune response to sarscov2 0.3778438640060071 0.4203662007695536 0.6742179553306009 1.0 0.8958069538959246 9 Q86UT6,Q9Y6M9,Q99623 3 +Envelope proteins and their potential roles in edmd physiopathology 0.3154432702505847 0.3811196355595902 0.7031144779409155 1.0 0.9154038599316416 18 Q8WXH0,P50402,Q9BTV4,P42167,Q14739,O94901 6 +Aryl hydrocarbon receptor pathway wp2873 0.4853338361638879 0.3779643947226067 0.7054570442688872 1.0 0.915964884153332 4 P07900,Q16543 2 +Apoptosis 0.3247355382626391 0.3711522607281518 0.7105241279820242 1.0 0.9171946280532288 14 Q9NR28 1 +Photodynamic therapyinduced ap1 survival signaling 0.389990243399332 0.3642325864954589 0.7156843352925142 1.0 0.9180085988562208 7 Q07820,P49327 2 +Cellular proteostasis 0.4384759924936845 0.329182993217176 0.7420173767080973 1.0 0.9301991031722128 5 Q9UHV9,O15212 2 +Calcium regulation in cardiac cells 0.2802760270048931 0.3238348793467637 0.7460630479933552 1.0 0.9304781967628512 29 P16615,P20020,Q14012,P05026,P62258,P23634,P62942,P10644 8 +Autosomal recessive osteopetrosis pathways 0.4673632303539077 0.3183180070281773 0.7502437265165978 1.0 0.9306168633726664 4 Q86WC4 1 +S1p receptor signal transduction 0.3556829056678132 0.3124010539410746 0.7547357494942606 1.0 0.9307897275710152 10 Q13510 1 +Glycosylation and related congenital defects 0.3522485911465473 0.2965443846686564 0.7668143762862452 1.0 0.9327956174191054 10 Q9H3H5,Q2TAA5,P15291,Q9BT22 4 +Oxysterols derived from cholesterol 0.3505144514162039 0.2906329022649397 0.7713320933899532 1.0 0.9327956174191054 9 Q9Y305,Q9UBM7,Q15125,O14734,P34913,P22307 6 +Glycogen synthesis and degradation 0.2996403806931239 0.2890255286534182 0.7725618418094509 1.0 0.9327956174191054 19 P30153,P30154,P46020 3 +Ketogenesis and ketolysis 0.4242097404522175 0.2800399368266045 0.779446865023778 1.0 0.9384231563058556 5 P23786 1 +Eicosanoid synthesis 0.566482271440582 0.2654965835340243 0.7906269413997498 1.0 0.9443144238343468 3 Q9H7Z7 1 +Inclusion body myositis 0.5638316534916359 0.2587908135925623 0.7957966461788757 1.0 0.9443144238343468 3 P05067 1 +Joubert syndrome 0.2948835858842814 0.2503710266120285 0.8023004336248656 1.0 0.9453462473719346 18 P42345,Q10713,P41208 3 +Estrogen receptor pathway 0.5590486982969747 0.2468891878911994 0.8049939841755926 1.0 0.9466853817770994 3 Q9HCL2 1 +Nuclear receptors metapathway 0.2802942122556178 0.2338287141092036 0.8151179567985936 1.0 0.9526086917009292 53 Q99735,P23786,Q86UP2,Q9H2J7,P09601,Q8N1S5,P49327,Q9HCL2,Q15043,Q96CN9,O15217,Q15067,P50416,P27105,P08183,O15439,Q16543,Q08431 18 +Mecp2 and associated rett syndrome 0.2829274339344049 0.2147587404699976 0.829955422618643 1.0 0.9526086917009292 21 Q99640,P35637,P52597,Q03518,P31943,P42345 6 +Regulation of wnt bcatenin signaling by small molecule compounds 0.4264029305622657 0.1976466520932956 0.8433215316390383 1.0 0.9619877884362764 4 Q07954 1 +Mitochondrial long chain fatty acid betaoxidation 0.2983333195646244 0.1841373684569374 0.8539056918771257 1.0 0.9640584325200962 13 Q9BY49,P23786,Q16836 3 +Omega9 fatty acid synthesis 0.34421743476097 0.181140572331604 0.856257239204488 1.0 0.9640584325200962 7 O95864,P49327,O60427 3 +Constitutive androstane receptor pathway 0.3891397473325239 0.1719099286449048 0.8635083408641486 1.0 0.9640584325200962 5 P08183 1 +Vitamin b12 disorders 0.5259447264523566 0.1718341530175662 0.8635679146325557 1.0 0.9640584325200962 3 Q99707,Q96EY8 2 +T cell receptor and costimulatory signaling 0.3646560154319151 0.1661649377719718 0.8680271514167524 1.0 0.9648272542255676 6 Q15118 1 +Splicing factor nova regulated synaptic proteins 0.2793484576722915 0.1590950260409663 0.8735940069544381 1.0 0.9674775158985398 17 P20020,Q92859,Q9UNS2 3 +Caloric restriction and aging 0.4100389194325552 0.1561860611508101 0.8758863634895637 1.0 0.9682525618211903 4 P43490 1 +Rala downstream regulated genes 0.4033255942134424 0.1403839337338673 0.8883566511682048 1.0 0.9726381541532796 4 P11233 1 +Gastric cancer network 2 0.2773349381897553 0.1283209896213528 0.8978949551057342 1.0 0.9801079581764568 15 Q86UE4,Q14739 2 +Head and neck squamous cell carcinoma 0.270123926786202 0.1023843264102292 0.9184516240041416 1.0 0.9971760489187824 16 P62942 1 +Primary focal segmental glomerulosclerosis fsgs 0.2600350278122998 0.0789923090003528 0.9370387404772882 1.0 1.0 21 P06756,Q14108,P08670 3 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.286234867532896 0.045048231431483 0.9640688648273654 1.0 1.0 8 P06756,P12814 2 +Complement system 0.2782054614349549 0.0449483861385495 0.96414844923108 1.0 1.0 11 Q07021,P26885,P98164 3 +Robo4 and vegf signaling pathways crosstalk 0.4327600789399575 0.0384758249488735 0.96930830610412 1.0 1.0 2 O94813 1 +Gpr40 pathway 0.3475317348377933 0.037333208017651 0.9702193277715324 1.0 1.0 4 P29992,P19174,P16885 3 +Apoptosis modulation and signaling 0.2544497932569824 0.0372198408018265 0.9703097188998592 1.0 1.0 19 Q9NR28 1 +Mthfr deficiency 0.2778176693187645 0.0266422269572936 0.9787450929598648 1.0 1.0 9 Q7L592,P21964 2 +Familial hyperlipidemia type 2 0.3625599097829181 0.005919450556785 0.9952769893746208 1.0 1.0 2 P34913 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..200e9a791d169526e253c44587e1097207e82fde --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APLP2", "APMAP", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG13", "ATG2B", "ATG3", "ATG7", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AURKA", "B3GALT6", "B4GALT1", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCR", "BCS1L", "BLM", "BLVRA", "BPTF", "BRAP", "BRCA1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP3", "CASP7", "CASP8", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLK3", "CLPTM1L", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COQ8B", "COQ9", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERA", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPAGT1", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFNB1", "EFTUD2", "EHD1", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERCC2", "ERCC3", "ERCC4", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC2", "EXOSC7", "EXOSC9", "EXT2", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAH", "FAM120A", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GCC1", "GCC2", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BPL", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIF15", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KLC1", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LZTFL1", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "METTL3", "MFGE8", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRI1", "MRPL19", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTDH", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTOR", "MTR", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA16", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NARS2", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEO1", "NFATC2IP", "NFRKB", "NGEF", "NIPBL", "NKRF", "NLRX1", "NME1", "NME3", "NONO", "NOP2", "NPC1", "NPC2", "NSD1", "NSDHL", "NSF", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSTM1", "OXSM", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PIAS1", "PIAS2", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCB3", "PLCG1", "PLCG2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PNKP", "PNP", "PNPLA8", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTPA", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "PTRH2", "PURA", "PUS1", "PVR", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGEF1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RICTOR", "RIF1", "RIPK1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SBF1", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR3", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX4", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE1", "SYNE2", "TAB1", "TAF6", "TAF7", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCP1", "TECR", "TEDC1", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TMED10", "TMEM165", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRRAP", "TSC2", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC21B", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2L3", "UBE2N", "UBE3A", "UBR5", "UBTF", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "ULK3", "UMPS", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP32", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS18", "VPS28", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WDHD1", "WDR1", "WDR26", "WDR48", "WDR5", "WDR73", "WFS1", "WIPI2", "WNK1", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYG11B", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ABCC4", "ABCD1", "ACOT8", "ACOT9", "ACOX1", "ACP6", "ACSL6", "ACTN1", "ACTN4", "AGPAT5", "AKT2", "ALG1", "ALG11", "APP", "ASAH1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6V1D", "ATP6V1E1", "ATP7A", "ATPIF1", "B4GALT1", "C1QBP", "CAMK1", "CDC37", "CDIPT", "CDS2", "CERS1", "CERS2", "CERS5", "CETN2", "CHST14", "CISD1", "CLPTM1L", "COA3", "COLEC12", "COMT", "COPS3", "COQ8B", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "COX7C", "CPT1A", "CPT2", "CRK", "CSNK1A1", "CYB5B", "CYP20A1", "CYP51A1", "DERL1", "DHCR24", "DHCR7", "DIABLO", "DNM1L", "DNM2", "DPAGT1", "EBP", "ECE1", "EMD", "EPHX2", "ESPL1", "ETFDH", "ETNK1", "EXOC7", "FADS1", "FADS2", "FASN", "FDFT1", "FGFR1OP", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FLOT1", "FMR1", "FOXRED1", "FUS", "GALNT1", "GBA", "GCC1", "GDAP1", "GLA", "GLB1", "GM2A", "GNA11", "GNPAT", "GNS", "GPAM", "GSTA4", "HADH", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HMGCR", "HMOX1", "HNRNPF", "HNRNPH1", "HS2ST1", "HSP90AA1", "ICMT", "IFT52", "IMPAD1", "IRS4", "ITGAV", "KDSR", "KTN1", "LBR", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRP1", "LRP2", "MAP3K4", "MAP4K4", "MAU2", "MCL1", "MFGE8", "MFN2", "MGST2", "MIA3", "MMAB", "MSMO1", "MTDH", "MTOR", "MTR", "NAGLU", "NAMPT", "NAP1L1", "ND1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB6", "NDUFB9", "NEFL", "NEFM", "NEO1", "NLRX1", "NPC1", "NPC2", "OCLN", "OPA1", "OSTM1", "P3H1", "P4HA1", "P4HB", "PDK1", "PDP1", "PDS5A", "PECR", "PFDN2", "PFDN6", "PHB2", "PHKA1", "PI4K2A", "PISD", "PKMYT1", "PLCG1", "PLCG2", "PLK1", "PMPCA", "POR", "PPP2R1A", "PPP2R1B", "PRKAG1", "PRKAR1A", "PTGES2", "PXMP2", "RAB4A", "RAB5B", "RABAC1", "RALA", "RPS6KA1", "RPS6KA3", "RRM2B", "RTN4", "SC5D", "SCARB1", "SCARB2", "SCO1", "SCP2", "SDHB", "SEL1L", "SGPL1", "SLC25A15", "SLC25A4", "SLC25A5", "SLC25A6", "SLC30A5", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC6A15", "SLIT2", "SMARCE1", "SMC3", "SPHK2", "SPTLC1", "SQLE", "STAG2", "STIM1", "STOM", "SUN1", "SYNE2", "TAP1", "TIGAR", "TIMMDC1", "TJP1", "TMEM43", "TMEM70", "TMPO", "TOR1AIP1", "TPM1", "TUBGCP4", "TXNDC15", "UGCG", "UGT8", "UQCR10", "UQCRQ", "VDAC2", "VDAC3", "VIM", "WAPL", "WFS1", "YWHAE", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c711a24fc4f2c9a98652462b1c2a779d0270bd91 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "vesicles", "1": "er", "2": "mitochondria", "3": "golgi"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4e50768eb44e5f06f0e26d428e328eb6f0f6259b --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:900848d5deeecb179f4db4f329fd3e3f790a089e1e94fd52c3e25fd3b9b88908 +size 205971 diff --git a/opencell_localization/advanced/plot_1.png b/opencell_localization/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5d664a853d92b604b6f347c554e904741a63be6c --- /dev/null +++ b/opencell_localization/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ea4d76fbf09635ca084ee34515811cd2bbf29c059abbd230c5a9e6cf29e99a6 +size 192890 diff --git a/opencell_localization/advanced/plot_2.png b/opencell_localization/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..eece211aa32f065793ffce7909cbf3500d21f9ad --- /dev/null +++ b/opencell_localization/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:192afbebacc926f52b4882cbfb069839833bfd1a1e2051d1ef4bc6334f25b951 +size 177797 diff --git a/opencell_localization/advanced/plot_3.png b/opencell_localization/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..3c969714a6d1eb27207eb53c945dbe0a97a69da5 --- /dev/null +++ b/opencell_localization/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5394dcb02ca1b69be6a5f81711858d589f82b855884c504a1d3b81669e2c1339 +size 195010 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..790983d91b929bc7d8e0360a3a53e2c7482c76ba --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "vesicles", "1": "er", "2": "mitochondria", "3": "golgi", "4": "nuclear_membrane"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a0551ca1e5fe524fe70dcad5ff957fdea91a4e71 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:59189549909a31db9c0890b5bc46f85179cf5784627f0d1edc45f27e562a9ee7 +size 144640 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7122d853fec7b0faefff2f8dbb4d9b4a7569a00c --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5bbd31d8167fd344670e2e44d12d46ae221dcf46e4fa15e53a49e3ee2e2af201 +size 132089 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..91a07ebd8a771c40ee09e8945209a9b6d1282b00 --- /dev/null +++ b/opencell_localization/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba882da0d399bd5a29b951a732cba35b90ff185ab5062c56d9cf7c97e363b592 +size 132713 diff --git a/opencell_localization/basic/plot_3.png b/opencell_localization/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6acc7cf9af730cf9afe0251a91c0d4876d4d5316 --- /dev/null +++ b/opencell_localization/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d99dae5ead9d79f4c316f058ac2d3830f55d3562895568c27e60eea02f1897da +size 138962 diff --git a/opencell_localization/basic/plot_4.png b/opencell_localization/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..cd7b5de370b4bd4dd439b0213c34ea11890b158c --- /dev/null +++ b/opencell_localization/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f70d083e0fda28aaeafca707c16e3754159c94a21f30a32ff564a4da7a410dfa +size 145542 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0c738dabef0391d82ea2fc3f570fc1eb076cf3d4 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b838764a0afa5ef9bb1145240c6d433b527a6d5eca29c98df1c36f3de24c38c1 +size 81689 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..76d02f9674c5abc2e0269c9754c1196dd36b9c9d --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +vesicles 69 194 4.06494761253368 4.804325204466053e-05 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 4.818960539811373e-07 1.0 0.6495539670118671 0.0097701613234431 2.532277653914674e-07 +er 55 97 3.100245771967899 0.0019336012529194 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 7.011720337060813e-18 1.0 0.1562534114898497 1.2864300655425559e-09 1.4780407292722944e-18 +mitochondria 7 11 2.5087332953034305 0.0121164928679795 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 7.461844281524028e-07 1.0 0.1180585699575878 0.0002022933287296 8.216606581665977e-07 +golgi 30 69 2.3794123481108467 0.0173402664094572 15.631067961165048 61.19417475728155 0.6692399314943925 0.523533703348586 6.922582002252161 5.868805558877078 1.075539554450533 0.3729249549278102 0.0003116019304315 1.0 0.6248041208228576 0.0983363279904071 0.0003600117972108 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..050bd61049690c9b4e69a8af86dc5bace7fb753a --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 103.52941176470588 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ec740588da7a12f46268c11ced32b5fb549ae19a --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f6b040f39019d4e8d3d54eb66007f0446afd8fb9 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +vesicles 0.3969117890377366 4.06494761253368 4.8043252044660534e-05 0.0008164214511994 0.0008167352847592 194 P61026,Q06136,Q9H2J7,Q93050,P50570,O00264,Q8IY95,O14653,P53985,P13473,O96005,O75787,O15258,Q8IZA0,Q15363,Q9Y3E0,P04439,P61019,Q9UM00,O00400,Q15392,P05023,P51798,Q9HD42,Q9H0U4,O95470,P62820,Q8NF37,O43808,O60499,P20020,O15400,Q86Y82,P02786,Q9Y371,O15173,Q8IZ07,O95249,O75845,Q5VW38,Q8NBN3,P49755,Q15125,O60476,Q9BTU6,P11279,Q969V3,P61020,Q9UI14,P49257,Q7Z6M1,O15127,Q9H2V7,O95674,P42345,O14735,Q10713,O43752,P30825,O00429,Q06481,Q969M3,Q15904,Q96L92,Q9Y3E7,O14964,Q96A49,Q9H6H4,O15269 69 +er 0.5459270725219855 3.100245771967899 0.0019336012529194 0.0323676254943882 0.016435610649815 97 Q99640,P61026,Q06136,O00264,Q8NHH9,Q8N4V1,Q8WVM8,O96005,P04843,Q15363,Q8N5B7,P46977,Q9Y3E0,Q9NQC3,P61019,Q9UM00,P51572,O00400,Q15392,O95470,Q6NUK4,Q96A33,Q9BRK0,Q8NF37,Q15006,O60499,Q9P2W9,Q86TM6,O15173,Q9NTJ5,O75845,P49755,Q12981,Q15125,Q9NR31,Q07065,Q969Q5,Q969V3,Q9Y487,O95674,Q13190,Q96N66,Q16850,O14735,Q8TBX8,Q13586,Q9Y5M8,Q9NPA0,Q969M3,P27824,P04844,Q00765,Q14739,Q9H6H4,O15269 55 +mitochondria 0.7238833438421435 2.5087332953034305 0.0121164928679795 0.1871741760737579 0.0686601262518841 11 Q15388,P45880,Q9NR31,Q8IWA4,Q969Q5,P21796,Q9Y277 7 +golgi 0.488287037672022 2.3794123481108467 0.0173402664094572 0.2572310751256341 0.0736961322401935 69 P61026,P36543,O14653,Q8WVM8,O75787,O15258,Q8IZA0,Q9Y3E0,P61019,Q9UM00,Q8TAD4,Q9H0U4,Q8IXU6,P62820,Q9Y371,P53365,Q9NTJ5,Q5VW38,Q8NBN3,P49755,Q9NR31,Q9Y487,Q9UI14,O15127,Q13190,O14735,Q969M3,P40616,Q15904,Q96A49 30 +nuclear_membrane 0.359113272767249 1.086451858345692 0.277279128871958 0.995995943991182 0.5892181488529109 31 P42166,Q8NFH5,P42167,P02545,P20700,Q14739,Q92973,Q5JTV8,Q9C0E2,P52292 10 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a70f5263a17b9b98296d7e95dfd317debb6e42b2 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1S1", "AKT2", "ALCAM", "ALDH9A1", "ANAPC16", "ANAPC2", "ANAPC4", "ANKRD13A", "ANXA11", "AP2B1", "AP2S1", "APLP2", "APPL1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG13", "ATG2B", "ATG3", "ATG4B", "ATG7", "ATL2", "ATM", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1", "BUB1B", "BUD23", "BYSL", "CAD", "CALD1", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP3", "CASP7", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2BP2", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDS2", "CEP170", "CEP250", "CERS5", "CETN2", "CHEK1", "CHEK2", "CHMP1A", "CHMP2B", "CHMP3", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLK3", "CLNS1A", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FAM50A", "FANCA", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FNBP1", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GPAT4", "GPR107", "GRB2", "GSK3A", "GSK3B", "GSPT1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HDAC3", "HEATR3", "HGS", "HIP1", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPB11", "HSPBP1", "HSPH1", "IDI1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF3", "ILK", "IMP3", "INPP4A", "INTS14", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IRAK1", "IST1", "KDSR", "KIAA0319L", "KIAA0368", "KIF11", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS1", "LIG1", "LMAN1", "LMNA", "LMNB1", "LNPK", "LPCAT1", "LSM14A", "LSM14B", "LSS", "LTV1", "MAN1A2", "MAP2K1", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MARK2", "MBOAT7", "MDH1", "MECP2", "MED14", "MED17", "MED20", "MED21", "MED24", "MED25", "MED4", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTOR", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1E", "MYO6", "NAF1", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NEK9", "NEMF", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "PABPC4", "PACSIN2", "PAIP1", "PAK2", "PAK4", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PEX3", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIN4", "PIP4K2C", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PMPCA", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "PPM1G", "PRKACA", "PRKCA", "PRKCD", "PRKDC", "PRMT9", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTGES3", "PTK2", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGRF", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP2", "REEP3", "REEP4", "REEP5", "RER1", "RHOA", "RHOG", "RICTOR", "RIOK2", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPLP1", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RRP36", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAR1A", "SAR1B", "SARS", "SBDS", "SC5D", "SCAMP1", "SCAMP2", "SCD", "SCFD1", "SCYL2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24C", "SEC24D", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC30A5", "SLC33A1", "SLC35F2", "SLC4A2", "SLC6A15", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX9", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQSTM1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STIM1", "STIP1", "STK26", "STRN3", "STT3A", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "SYVN1", "TARDBP", "TCOF1", "TFRC", "TGFBRAP1", "TIA1", "TJP1", "TJP2", "TLK2", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM192", "TMEM87A", "TMPO", "TMPO", "TNPO1", "TNPO3", "TOLLIP", "TOMM20", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM28", "TRIM33", "TRIR", "TRMT1L", "TRRAP", "TSG101", "TSR1", "TSR2", "TTK", "TUBB4B", "TUBG1", "TWISTNB", "U2AF2", "U2SURP", "UBA1", "UBA5", "UBE2M", "UBTF", "UFC1", "UGDH", "ULK3", "UPF1", "USP10", "USP22", "USP32", "USP36", "USP7", "UTP14A", "UTP4", "UTP6", "UTRN", "VAPA", "VAPB", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS18", "VPS25", "VPS28", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS4A", "VRK3", "WAPL", "WBP2", "WDR12", "WDR3", "WDR46", "WDR75", "WNK1", "XPO1", "XPO4", "XPO5", "XPOT", "YES1", "YIPF5", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZNF326", "ZNF598", "ZYX"], "leading_proteins": ["ANKRD13A", "APLP2", "ARFIP2", "ARL1", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "BCAP31", "BNIP1", "CANX", "CCDC47", "CDIPT", "CDS2", "CERS5", "CHMP1A", "CHMP3", "CKAP4", "CLCN7", "CLPTM1", "CYP51A1", "DHCR24", "DNM1L", "DNM2", "EBP", "EMC2", "EMC7", "GOLT1B", "GOSR1", "GOSR2", "GPR107", "HGS", "HLA-A", "KDSR", "KIAA0319L", "KPNA2", "LAMP1", "LAMP2", "LBR", "LMAN1", "LMNA", "LMNB1", "LPCAT1", "MAN1A2", "MBOAT7", "MFN1", "MMGT1", "MTOR", "NCLN", "NUP35", "PGRMC1", "PGRMC2", "PI4K2A", "PIP4K2C", "PKMYT1", "PMPCA", "RAB10", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB5B", "RABAC1", "RABEPK", "REEP2", "REEP3", "REEP4", "REEP5", "RER1", "RPN1", "RPN2", "RTN4", "SACM1L", "SAR1A", "SC5D", "SCAMP2", "SCFD1", "SGPL1", "SH3GLB1", "SLC16A1", "SLC25A17", "SLC30A5", "SLC33A1", "SLC35F2", "SLC6A15", "SLC7A1", "SNX27", "SPNS1", "SPTLC1", "SRPRB", "STIM1", "STT3A", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "SYAP1", "SYVN1", "TFRC", "TMCO1", "TMED10", "TMED2", "TMEM192", "TMEM87A", "TMPO", "TNPO1", "TOMM20", "TOR1AIP1", "VDAC1", "VDAC2", "VDAC3", "XPO4", "YIPF5"]} \ No newline at end of file diff --git a/panther_protein_class/advanced/idx2term.json b/panther_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1241fcc8607c3ae6575a658c5a75d3961ee47de9 --- /dev/null +++ b/panther_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "primary active transporter", "1": "secondary carrier transporter", "2": "membrane trafficking regulatory protein", "3": "oxidase", "4": "membrane traffic protein", "5": "calmodulin-related", "6": "transporter", "7": "SNARE protein", "8": "ATP-binding cassette (ABC) transporter", "9": "protein modifying enzyme"} \ No newline at end of file diff --git a/panther_protein_class/advanced/plot_0.png b/panther_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..195e84d266173aa46298118fc220e577203ded3d --- /dev/null +++ b/panther_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e9b7eaa1969f89d6454816c644419215d40fcea3af04d96c018da56a07d95c0f +size 198132 diff --git a/panther_protein_class/advanced/plot_1.png b/panther_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b2a857d32c9fc1c9f9816216c84bf1a535ac6b0d --- /dev/null +++ b/panther_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:239a6fd7f7579f0fe0065097e828a482b44850c51b96a87476f69d8414192058 +size 196510 diff --git a/panther_protein_class/advanced/plot_2.png b/panther_protein_class/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..35a63855f537cd5348780313c36b9cfde9a3841b --- /dev/null +++ b/panther_protein_class/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db4486bd6bf009c13dcafdb57bab655b1e35357ffef9e79c873f5591ae6788c7 +size 204459 diff --git a/panther_protein_class/advanced/plot_3.png b/panther_protein_class/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..fd70672ddb539cf285025a88fa3cd16b1e059bde --- /dev/null +++ b/panther_protein_class/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64456886e71c18e954454a1c04fbab954e1f27b49360d6659746a95d3ff55d51 +size 190891 diff --git a/panther_protein_class/advanced/plot_4.png b/panther_protein_class/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..1f066c7a68fcc58242ed62b34c3a814a55b5c758 --- /dev/null +++ b/panther_protein_class/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e1d396fb44ef8e361d8f99fed814df39fe22f3536d04519122cc7cafc52eda8 +size 208623 diff --git a/panther_protein_class/advanced/plot_5.png b/panther_protein_class/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..07ab1d52e8dc705ea31c655be7d5a7e44231d20a --- /dev/null +++ b/panther_protein_class/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a87c248a216b5bd295bb88794b35834eb3476a33f813c350c96e7938a6cfbc5b +size 191697 diff --git a/panther_protein_class/advanced/plot_6.png b/panther_protein_class/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..b841538a39a7a0752d9dc22122d188f8c7b7ce45 --- /dev/null +++ b/panther_protein_class/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8f6ea47dce0b0dfef172dce597079dadbcdad5d9b8a2d71d7b080fa427b130cb +size 202696 diff --git a/panther_protein_class/advanced/plot_7.png b/panther_protein_class/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..4137cb5a5758e93d7df3f01a09ed57a8899eae45 --- /dev/null +++ b/panther_protein_class/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a038d1ea192b18d327413ae7130f66920c22f43cf5dbac7018e46d9714b5731 +size 187236 diff --git a/panther_protein_class/advanced/plot_8.png b/panther_protein_class/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..4a4852b531f0c5982c3bbcdc26622678e2333aa6 --- /dev/null +++ b/panther_protein_class/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c7bb587a3c82cbc617fffa264d0274fd445ec42a986288e6c21eaa0d219a6a3 +size 190555 diff --git a/panther_protein_class/advanced/plot_9.png b/panther_protein_class/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..652af8c7bb949d81b065b5139500d6c6d42bb5e5 --- /dev/null +++ b/panther_protein_class/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b37dd179143a69cddba357c8ce011b37d7a551f0ddc8bcbe956b725a85970cc7 +size 201021 diff --git a/panther_protein_class/basic/idx2term.json b/panther_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fce22f36426be32dd7cb1e625e7cd866575a5bd9 --- /dev/null +++ b/panther_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "primary active transporter", "1": "secondary carrier transporter", "2": "membrane trafficking regulatory protein", "3": "oxidase", "4": "membrane traffic protein", "5": "calmodulin-related", "6": "transporter", "7": "SNARE protein", "8": "ATP-binding cassette (ABC) transporter", "9": "protein modifying enzyme", "10": "ATP synthase", "11": "mitochondrial carrier protein", "12": "transfer/carrier protein", "13": "serine protease", "14": "transmembrane signal receptor", "15": "glycosyltransferase", "16": "kinase", "17": "transferase", "18": "metalloprotease", "19": "acyltransferase", "20": "oxidoreductase", "21": "non-motor microtubule binding protein", "22": "chaperone", "23": "DNA helicase"} \ No newline at end of file diff --git a/panther_protein_class/basic/plot_0.png b/panther_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..32b5c6a8cce6264a723ade6af3c067d19bb91c2c --- /dev/null +++ b/panther_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:04688c97b0e40de70926831defe9b91086feef8cba6fb3dddb09dba9d9045628 +size 144790 diff --git a/panther_protein_class/basic/plot_1.png b/panther_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..da25d3c6df4fb26cd05ff86f9e165854b551e39f --- /dev/null +++ b/panther_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8eb4064fa0ee8e0fe8efbf3d0e467ebe7474bde0a035b327fa060ee029f988e3 +size 145190 diff --git a/panther_protein_class/basic/plot_10.png b/panther_protein_class/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..569ea81d9a37293e0743395f105202976beea198 --- /dev/null +++ b/panther_protein_class/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8c4043d49c166a2d87a9516c43651aabcb754511f7f78600191ed751a1a0c5f +size 133591 diff --git a/panther_protein_class/basic/plot_11.png b/panther_protein_class/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..aad2a0e03bc9f9ee2b6563c49f5da0cad4e72e69 --- /dev/null +++ b/panther_protein_class/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:144831ae70a5a4f7bb9896fc8400b3417647ff5d5a22e3ae5b420eff4ca679ee +size 137693 diff --git a/panther_protein_class/basic/plot_12.png b/panther_protein_class/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..1206b59317d56e1e7b134932f7ad79c92fd170cd --- /dev/null +++ b/panther_protein_class/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8500e777b9d5b6e9a9aeb320590e299728865f78354ebaf0e6c1bc7cea7cade8 +size 136143 diff --git a/panther_protein_class/basic/plot_13.png b/panther_protein_class/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..c1d40cb114266a86e3fcf93e5bd011d52011c6da --- /dev/null +++ b/panther_protein_class/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:602c4fc0272312376f866089e8dc0ac215b2b46022f3f36a3141ea71eebe3b55 +size 131250 diff --git a/panther_protein_class/basic/plot_14.png b/panther_protein_class/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..fb2b9f846ea5c6e02d44470e114560c91be2e86b --- /dev/null +++ b/panther_protein_class/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31fb00e59dd55046951c0886a504c52931cb09f6668a77a6069507990484f157 +size 138161 diff --git a/panther_protein_class/basic/plot_15.png b/panther_protein_class/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..496d5f0381d9592f54c14996a9e9e42659c087d3 --- /dev/null +++ b/panther_protein_class/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9cf994c04f7d33786543aa9013565a4e6225690625a24bcedfa86399c9cb3dff +size 137693 diff --git a/panther_protein_class/basic/plot_16.png b/panther_protein_class/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..272e0ada8ba07df434c674f85c8f474e80b2c034 --- /dev/null +++ b/panther_protein_class/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38ddfacf1c847177ef8a621dcdfb6b343f29158031ef6726d583f7282267fdc4 +size 127935 diff --git a/panther_protein_class/basic/plot_17.png b/panther_protein_class/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..f6ce6338a57e4d814cb5813687f37e2349716732 --- /dev/null +++ b/panther_protein_class/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bbd13608d595d3f47bf60312641e2b49a9fdc3e04654ce0fc0bdad6a4a5e2b0b +size 140664 diff --git a/panther_protein_class/basic/plot_18.png b/panther_protein_class/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..c2c187fc46b2e888999d94c695043092b313ff82 --- /dev/null +++ b/panther_protein_class/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:835d3fcde58d11e7b99334736cabd0edd8e6502b557e6201c2eb855b66eb240f +size 144321 diff --git a/panther_protein_class/basic/plot_19.png b/panther_protein_class/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..e24ca0dae9dfc2972693ff0f49c8567e21c6a23a --- /dev/null +++ b/panther_protein_class/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2bb771936abaab8e660adaea23023fe9e2603b378aa22a8c13ba4d11788f6dcd +size 138395 diff --git a/panther_protein_class/basic/plot_2.png b/panther_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..f84b59c209c1140c8899c404373f0daef865e25a --- /dev/null +++ b/panther_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b3214de6557fd03bc9aaa05b10889157133406f26d8aaf551679ca8449fe7c91 +size 149633 diff --git a/panther_protein_class/basic/plot_20.png b/panther_protein_class/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..457a96b312cfe9aaef3ca9a529c235905ae70b92 --- /dev/null +++ b/panther_protein_class/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:caac777bfc488408a131838b41085ecfabdb7889234ff6add6e0f7db892045be +size 141674 diff --git a/panther_protein_class/basic/plot_21.png b/panther_protein_class/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..fe5b51d30537292dd8bf5b9cc422e4e489b3ddec --- /dev/null +++ b/panther_protein_class/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0673c55a3d25680583a3bbf1be7b2fa057acc3578dc1342e9a3369045656cc23 +size 157816 diff --git a/panther_protein_class/basic/plot_22.png b/panther_protein_class/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..580c8546aa10e748fb5e428268ce31a70142e7e3 --- /dev/null +++ b/panther_protein_class/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d15c9d6811d6dfaf6d17511405bee7cc217c9fdcd9bb34c33bdd83f64772405a +size 144615 diff --git a/panther_protein_class/basic/plot_23.png b/panther_protein_class/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..ba34df4227d9541f9bad176c9d3a81eeaed3a9e6 --- /dev/null +++ b/panther_protein_class/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cc39d2e696594e99a1afa3a13bd8b5b13d3a965b19303877fd49e1d602f1ce0e +size 139782 diff --git a/panther_protein_class/basic/plot_3.png b/panther_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6dd9d3765eb10611e6141d6d5c87169ff607246a --- /dev/null +++ b/panther_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fbee2926f787ef7e37a28f7ae7572933374d712e67110490a1152f5b4a244b4 +size 134986 diff --git a/panther_protein_class/basic/plot_4.png b/panther_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7f1f6fe887040e6a5ba7a3ce387f5fd823484cff --- /dev/null +++ b/panther_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f0ea0939337bc19cb90e112d0a26d250301274eb9b436fc1ecd806a232a55c9 +size 142582 diff --git a/panther_protein_class/basic/plot_5.png b/panther_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..6b4cdb0609ad1b798b7a41cf4c06b02a3b711ae7 --- /dev/null +++ b/panther_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b602118304ab0e07de35b5e9e109f6dcab9a14633e18646014322431b679d82b +size 139433 diff --git a/panther_protein_class/basic/plot_6.png b/panther_protein_class/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..0edd4dc681db5fc549fc12e05702fe44f1af5448 --- /dev/null +++ b/panther_protein_class/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:168c35cd40291b928ede287f10698b4cd145b5ca4e7835d4cc38bf3e4e2b1e4b +size 135798 diff --git a/panther_protein_class/basic/plot_7.png b/panther_protein_class/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..01f7de5ae5fae9bb1ad574df1f28f8cb1447f26f --- /dev/null +++ b/panther_protein_class/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4db19aa919ee354e0974b9f56767fbfed88b80f5807cf7983b34513bac638416 +size 136132 diff --git a/panther_protein_class/basic/plot_8.png b/panther_protein_class/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..91107ba242c26d111b4c37837772f993cc4a853b --- /dev/null +++ b/panther_protein_class/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06e2811f3b532903f62d8b70d60d2d0773e206b05b34d1862ae7e26bab132043 +size 146727 diff --git a/panther_protein_class/basic/plot_9.png b/panther_protein_class/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..28f87d4c1ead24dc5ddc8bac0b49aeb6caa7c449 --- /dev/null +++ b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8faffa12c7c488f32017f744a041f6dcd04a9800c570795fc10034ab33155934 +size 140569 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a18f90a5d6ef324d6085b1c91806c489b10c1c5d --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f95c5ea5ea7835b987985a69deffd0ccee61009cde6bd351a1b711cf2cfbcb98 +size 95507 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4335388f436369bbdf6fefaf093f749e29b505a1 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,16 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +primary active transporter 19 29 3.695056098175972 0.0002198382442628 8.614077669902912 23.45631067961165 1.2392440710771837 0.271771563990288 4.792195908457348 3.1431129799052804 1.4794913205770832 0.3014776193450941 3.118728860038144e-05 0.0343104139968933 0.1194965359594502 0.0037630129831157 3.58661766917345e-05 +secondary carrier transporter 9 18 3.2054736035766616 0.0013484041382247 6.104368932038835 14.6626213592233 1.264699085385324 0.2718921136589474 3.483843477892234 2.781747184831951 1.2916784116683784 0.322278600042778 0.0019470200972528 1.0 0.1487873266068847 0.0073240386864259 0.0021618403257682 +membrane trafficking regulatory protein 8 20 3.082849229997007 0.0020502900232772 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0034897521329341 0.2217755071466549 0.0919415891551245 0.0390247080582918 0.0009271037060534 +oxidase 10 15 3.071158246691188 0.0021323010765648 5.111650485436893 13.890776699029129 1.1786899361665428 0.2351652471103072 2.6295852591466065 1.831549924215542 1.2715889014379809 0.2754701040210626 0.0194194773536838 1.0 0.0038117145357013 0.0449350347407693 0.0205229364106292 +membrane traffic protein 33 79 3.0040503221147845 0.0026641125673783 17.393203883495147 64.0364077669903 0.6866153002436179 0.5279969401351168 6.983388919650095 8.417857504136053 1.0746394007588131 0.378481933491251 0.0008973469039005 0.5122009359255594 0.4276292777269929 0.0111359232759007 0.000378709337631 +calmodulin-related 8 13 2.903740975547809 0.0036873308608189 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 1.2802833229834784e-06 0.1114021565620111 0.0016986126979642 0.0002861885476851 1.4416472873703857e-06 +transporter 24 62 2.871207787618277 0.0040890664191162 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 1.0596158932126862e-05 0.0021714502363067 0.0053131066018268 2.5208008683948227e-05 1.2860666572015533e-05 +SNARE protein 9 13 2.850114987329918 0.0043703426066059 4.660194174757281 11.12378640776699 0.9288896561072936 0.3201954718639376 2.5506648592929815 2.745113440103806 1.1546709449924732 0.3042666981599379 0.0003471406336639 1.0 0.2445730022705269 0.0049571663496986 0.000378511976274 +ATP-binding cassette (ABC) transporter 9 12 2.827951266938664 0.0046846937371365 2.686893203883495 7.684466019417476 0.6951371488068213 0.3450534093319853 1.8332217537175712 2.163791049328932 1.0940500371142112 0.2754733493972692 0.095439119896664 1.0 1.0 0.1060727287920157 0.0986013223955862 +protein modifying enzyme 7 29 2.771589683848259 0.0055783303286229 6.487864077669903 24.82281553398058 0.9737051724681342 0.3238157719208961 2.575528657386725 2.871041189126622 1.1448244681235864 0.2930923238696635 0.0016284637892819 0.0303491574999332 0.0022887430854204 7.125032306985868e-05 0.0017963005545976 +oxygenase 4 7 2.625182582272445 0.0086602514193556 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0049505599365773 0.0001849020150097 0.0015052123544451 0.0024379570615939 0.0052582215982291 +ATP synthase 8 23 2.4654941954674428 0.0136824392055647 6.381067961165049 20.483009708737864 0.8573640874951715 0.3249378356888472 2.8850015270213047 1.3977105655851854 1.2517106680730556 0.3017789026221172 9.759955757573273e-06 0.0092510900433489 0.0354914601129098 0.0063239101987386 1.0948299098753309e-05 +mitochondrial carrier protein 5 7 2.4457693470562973 0.0144543437933353 3.2936893203883497 7.065533980582524 1.4583792806536486 0.1840967072966826 2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 0.0002321391353102 1.0 1.0 0.0382400085743442 0.0002481332774246 +transfer/carrier protein 5 12 2.222675650716601 0.026237678937043 4.33252427184466 11.024271844660197 0.5751131114698911 0.3717158985009051 2.2946984989028927 1.3525930522279908 1.248808855129494 0.3186564966906889 0.0007580426681942 0.1071891284628969 0.2070995190727305 0.0024379570615939 0.0008169542553505 +serine protease 6 18 2.030954299060985 0.0422596307943026 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.0083585032956262 0.2068720246493716 0.0012207780133745 0.0304079267330467 0.0090060858517451 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..941f7a72130e4e9e5543c39ca612f438ec818b49 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 158, + "title": "Average number of proteins per term", + "value": 15.151898734177216 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7222d0e42d291f907b3ec81ce59d2030e85b43e2 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e98056e55f65865a4574b9c772adebdedd37f54a --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,47 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +primary active transporter 0.6597392434829835 3.695056098175971 0.0002198382442628 0.0341418141960824 0.0271796575769077 29 Q15388,O75381,Q9H2J7,Q8N4H5,Q9NS69,P23634,P05023,Q9Y5J6,Q96B49,Q9BUN8,P20020,P12270,P05026,Q9H9B4,O96008,P16615,Q9GZP9,Q04656,Q6NTF9 19 +secondary carrier transporter 0.710344843590111 3.2054736035766616 0.0013484041382247 0.1919987071455017 0.0426095707679034 18 O75746,Q8TB61,Q8N1S5,Q9BQT8,Q9Y6M7,Q9UBX3,O00400,Q96ES6,O95202 9 +membrane trafficking regulatory protein 0.6675186337383074 3.082849229997007 0.0020502900232772 0.2769510605858296 0.0457072282377164 20 P24390,P13473,Q8WVM8,O43760,Q8WTV0,P11279,O43731,Q14108 8 +oxidase 0.7271772950460684 3.071158246691188 0.0021323010765648 0.2862790871655302 0.0457072282377164 15 O75880,O43819,O14548,O75845,P20674,Q8NB78,P15954,P13073,P14406,Q15800 10 +membrane traffic protein 0.5475398881681737 3.0040503221147845 0.0026641125673783 0.343932425644487 0.0467699761828636 79 Q96D71,Q96PC5,Q8N1B4,Q12907,P43307,Q9BRG1,P51572,Q9BXS5,Q9HD42,Q9UPT5,Q6NUK4,A6NIH7,Q9BRK0,Q96A65,Q8N2H4,Q9NX40,Q9Y2T2,Q96RL7,O60313,P11717,Q9UI14,P49257,O43493,Q5JRA6,O00429,P78537,Q00765,Q9Y3E7,P40855,O95159,Q96ED9,Q9H6H4,Q12768 33 +calmodulin-related 0.7382958005782297 2.903740975547809 0.0036873308608189 0.442155506011572 0.056937046959044 13 Q8IYU8,P80303,Q9BRK5,P41208,Q99584,Q14257,Q02818,O43852 8 +transporter 0.5344444071407957 2.871207787618277 0.0040890664191162 0.4765935799159371 0.056937046959044 62 O60830,P53985,Q8N1F7,Q99595,Q15070,O15397,Q8N8Q8,P52292,Q7Z3B4,Q9Y584,Q9H2D1,Q9NR77,Q9C0E2,O43615,O95373,Q567V2,Q9UJZ1,Q9H2V7,Q9Y619,Q99805,Q92544,Q9HD45,Q92973,Q8NFH4 24 +SNARE protein 0.7289165336293787 2.850114987329918 0.0043703426066059 0.4994398132543272 0.056937046959044 13 O95249,O43752,O14653,O60499,Q9P2W9,O15400,O95721,Q86Y82,Q13190 9 +ATP-binding cassette (ABC) transporter 0.7505334296897186 2.827951266938664 0.0046846937371365 0.5238016483515447 0.056937046959044 12 P33897,Q99758,O75027,Q03518,O14678,P08183,Q9NP58,P33527,O15439 9 +protein modifying enzyme 0.5456565568332945 2.771589683848259 0.0055783303286229 0.5868083195042679 0.0629554422801736 29 P51812,Q92791,P50897,Q9UMR5,O60725,Q15418,Q86YN1 7 +oxygenase 0.8395515157399638 2.625182582272445 0.0086602514193556 0.7469780796695535 0.0912213149505463 7 P30519,P09601,Q16850,Q6UW02 4 +ATP synthase 0.546431813595875 2.4654941954674428 0.0136824392055647 0.8865906252025016 0.1029440664037731 23 P56385,Q93050,O75964,Q15904,P00846,P06576,Q6IN85,P24539 8 +mitochondrial carrier protein 0.8015617408904736 2.4457693470562973 0.0144543437933353 0.899786506031659 0.1038084690612264 7 Q6NUK1,Q9BSK2,Q9HC21,Q9NZJ7,Q70HW3 5 +transfer/carrier protein 0.6445985809495356 2.222675650716601 0.026237678937043 0.9850180409159578 0.1488193377062837 12 P17900,Q9Y5M8,P12236,O15127,P12235 5 +serine protease 0.5375425127354637 2.0309542990609852 0.0422596307943026 0.9989106902861132 0.1963829901617592 18 Q16740,P67812,Q9HB40,O14773,P10619,P42785 6 +transmembrane signal receptor 0.661480461676622 1.940478807726618 0.0523215272357631 0.9997946756604804 0.2224325755164154 8 O15173,O00264,Q99720,O75787,Q8WUJ1 5 +major histocompatibility complex protein 0.7714446952595758 1.7823253316483445 0.0746961940915 0.999995291017668 0.2878536260111466 5 P01889,P10321,P04439,P55899 4 +glycosyltransferase 0.4408934753984009 1.6736071824897505 0.0942078260007368 0.999999837627258 0.3166986491088601 24 Q9H3H5,P15291,Q10472,Q10471,Q9NYU2,Q16739,P04844,P04843,O60762,Q9BT22,P46977,Q8NBN7,Q6UX07,Q8N4A0 14 +voltage-gated ion channel 0.9472645234066528 1.634795515860591 0.1020919211141566 0.9999999592021852 0.3291943578783011 3 P45880,P21796 2 +G-protein coupled receptor 0.771942281894924 1.5594931992148944 0.1188796929601672 0.9999999979319394 0.3567900119370147 4 Q5VW38,Q9NPR9 2 +kinase 0.4532491882709394 1.557085296404276 0.1194502355083622 0.9999999981331174 0.3567900119370147 21 Q8TBX8,Q53H12,Q9BTU6,Q9BRR6,Q9NRA0,Q9HBU6,Q8WVC6 7 +amino acid transporter 0.7209367945823707 1.556106685508869 0.1196827255231758 0.9999999982094048 0.3567900119370147 5 P30825,O14925,Q96QD8,O75915 4 +phosphatase modulator 0.6486544008150339 1.4314491220022625 0.1523015386529238 0.9999999999954066 0.4033122075536591 6 P30154 1 +protein-binding activity modulator 0.7016132291123173 1.2564710409258464 0.2089452389871713 1.0 0.4512814047181236 4 O14737,P14314 2 +transferase 0.3760496346314419 1.254084552642318 0.2098112744322549 1.0 0.4512814047181236 31 O14735,Q8NCH0,O15217,Q9NRN7,P43490,O43505,Q7LGA3,Q9NXS2,O95674,P37268 10 +galactosidase 0.8448956570783925 1.2343511915613985 0.2170720680922619 1.0 0.4512814047181236 3 P06280,P16278 2 +metalloprotease 0.3755595465236609 1.2145954993558552 0.2245204062623309 1.0 0.4607042102525752 29 P02786,Q7Z2K6,O75844,Q10713,P55786,Q9BYT8,Q5JRX3,Q9NZ08,Q96TA2,P42892,Q96E52,Q9UIQ6 12 +phospholipase 0.5092805861446402 1.1524277743180698 0.2491453332651469 1.0 0.4859871932826324 10 Q8NHP8,Q8IV08,Q9NP80 3 +acyltransferase 0.4022498801240634 1.138102112806985 0.255077846005608 1.0 0.4914914593766593 21 P23786,Q8NCC3,Q92604,Q9HCL2,Q8NF37,P50416 6 +oxidoreductase 0.3549060974647484 1.112038638815965 0.2661215375545565 1.0 0.49433995962971 45 O43169,P16435,Q9P2K2,Q86Y39,Q8N4Q0,Q8N0U8,O14949,P00403,Q15067,Q9Y320,Q9Y6M9,Q16134,O43676,O96000,Q08431 15 +cytoskeletal protein 0.5208143231491283 1.01462473513257 0.3102847439065104 1.0 0.5023912825795893 7 P27105 1 +viral or transposable element protein 0.7831970679447211 1.0052230166440588 0.3147894745277173 1.0 0.5023912825795893 2 Q9H2J4 1 +kinase activator 0.513994210259936 0.9787185508516782 0.3277190634544182 1.0 0.5177961202579808 7 P46020 1 +Hsp90 family chaperone 0.6064880112835016 0.8490538237278874 0.3958513431660586 1.0 0.5887438626951941 4 P14625,P07900,P08238 3 +tight junction 0.7042571186918539 0.6946390465126313 0.4872815357415581 1.0 0.6587563540513722 2 Q07157 1 +glycosidase 0.5284736570709712 0.6878457350027734 0.4915499318946457 1.0 0.6587563540513722 5 Q9BTY2,P07686,P06865 3 +aspartic protease 0.6971923808984195 0.6744199839327821 0.5000443412113105 1.0 0.6587563540513722 3 Q8TCT8 1 +lyase 0.3397072461568906 0.4618567725400136 0.6441840349928416 1.0 0.7822154646884355 14 P22830,Q9UHG3 2 +nucleic acid metabolism protein 0.44184616371718 0.453850317560959 0.6499365646052386 1.0 0.7822154646884355 6 Q9NYF8,Q96FV9,Q9Y2W1 3 +ion channel 0.4087549479674933 0.4489101633109351 0.6534964641700853 1.0 0.7822154646884355 7 Q9C0H2,P51797,P51790 3 +non-motor microtubule binding protein 0.2928757017534611 0.3072104903125797 0.7586831612582428 1.0 0.8501555991404423 22 Q9UH99,Q9BSJ2,Q9BZD4,Q4ZIN3,Q9UGJ1 5 +kinase modulator 0.3985747638054512 0.2816462363505597 0.7782147832596396 1.0 0.865900956021289 6 P54619 1 +esterase 0.3651670161938607 0.2602410796936748 0.7946778185692382 1.0 0.8734454921843402 7 O14734,Q9Y305,Q9NUJ1,Q969T7 4 +chaperone 0.3014167040987569 0.2572846415065742 0.7969590477843913 1.0 0.8734454921843402 77 Q9Y2R0,Q02790,O15260,P07237,Q15006,P46379,Q00688,P62942,Q96I36,P49321,Q9Y680,O75937,Q9NWM8,Q9NVH1,Q16543,P27824,Q96JJ7,Q96KC8,Q7KZN9 19 +DNA helicase 0.3264556246467092 0.2288209511984297 0.8190080820672219 1.0 0.8802944011334766 11 O60264,P19447,P18074,P12956,P13010,P54132,Q9H4L7,Q96RR1,P28370,P51532 10 +translation factor 0.3701692036657756 0.1835571947450056 0.8543608460870122 1.0 0.9059665347768318 6 P51114,Q06787 2 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..381db8f6723c17147c8505fef0bc55117a17ea1b --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "membrane-bound signaling molecule", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASB6", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD2B", "ATAD5", "ATF7IP", "ATG3", "ATG4B", "ATG7", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CEP170", "CEP250", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC27", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERA", "DERL1", "DERL2", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAHD2A", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD3", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGALS1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "MFGE8", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NENF", "NFRKB", "NFS1", "NGEF", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OTUD6B", "OXA1L", "OXNAD1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PAPOLA", "PARG", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PURB", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RALGAPA1", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "S100A11", "S100A13", "SACM1L", "SAE1", "SAMHD1", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC6", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STAT1", "STAT3", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAP1", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL3", "TBPL1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TES", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "TGS1", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM259", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRIM21", "TRIM26", "TRIM27", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TTK", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGCG", "UGDH", "UGGT1", "UHRF1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WASHC5", "WDHD1", "WDR1", "WDR4", "WDR82", "WIZ", "WNK1", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YEATS4", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFPL1", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF24", "ZNF281", "ZNF326", "ZNF598", "ZNF622", "ZRANB2", "ZW10", "ZYX", "ZZZ3"], "leading_proteins": ["AASDHPPT", "ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ABHD10", "ACOT8", "ACOT9", "ACOX1", "ADPGK", "AGK", "ALG1", "AP1M1", "AP3M1", "ARL6IP5", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP7A", "B4GALT1", "B4GAT1", "BAG6", "BCAP31", "BCLAF1", "BLM", "BLOC1S1", "CALU", "CANX", "CDC37", "CDIPT", "CDS2", "CETN2", "CHMP1A", "CHMP3", "CHST14", "CLCN3", "CLCN6", "CLPP", "COA3", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "COX7C", "CPT1A", "CPT2", "CTSA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DCAKD", "DERL1", "DERL2", "DHRS13", "DNAJC1", "DNAJC11", "DNAJC8", "DNM1L", "DOLPP1", "DPAGT1", "DPM1", "ECE1", "EMC2", "ERAP1", "ERCC2", "ERCC3", "ERMP1", "ETFDH", "ETNK1", "EXOC4", "EXOC7", "FCGRT", "FDFT1", "FECH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP7", "FMR1", "FUCA2", "FXR1", "GALNT1", "GALNT2", "GALNT4", "GLA", "GLB1", "GM2A", "GOSR1", "GOSR2", "GPAM", "GPR107", "GPR108", "GSTA4", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HOOK2", "HS2ST1", "HSP90AA1", "HSP90AB1", "HSP90B1", "ICMT", "IGF2R", "IPO7", "IPO8", "KDELR1", "KDELR3", "KDM1B", "KPNA2", "LAMP1", "LAMP2", "LETM1", "LMAN1", "LMAN2", "LNPEP", "LPCAT1", "LPGAT1", "MFGE8", "MFSD3", "MIA2", "MIA3", "MICU2", "MPV17L2", "MSMO1", "MTCH1", "NAMPT", "NASP", "NDUFA11", "NDUFB10", "NDUFB3", "NDUFB9", "NLN", "NPEPPS", "NT5C3B", "NUCB1", "NUCB2", "NUF2", "NUP37", "NUP54", "NUP93", "OCIAD1", "OMA1", "OPA1", "OXA1L", "P3H4", "P4HB", "PCYOX1", "PDCD5", "PDCL3", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PHKA1", "PI4K2A", "PIP4K2C", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "PMPCA", "PNPLA8", "POR", "PPP2R1B", "PPP4R3A", "PPT1", "PPT2", "PRCP", "PRKAG1", "PRKCSH", "PXMP2", "QPCTL", "RABAC1", "RCN2", "RDH13", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RHBDD2", "RPN1", "RPN2", "RPS6KA1", "RPS6KA3", "S100A13", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SDF4", "SEC11A", "SFXN1", "SIGMAR1", "SLC16A1", "SLC25A10", "SLC25A12", "SLC25A15", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A6", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A11", "SLC4A7", "SLC6A15", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SNAP29", "SPHK2", "SPNS1", "SPPL2A", "SRPRB", "SSR1", "STOM", "STOML2", "STT3A", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "SUN2", "SURF4", "SYNGR2", "SYS1", "TAP1", "TFRC", "TGOLN2", "THOC1", "THRAP3", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TJP1", "TM9SF2", "TM9SF3", "TM9SF4", "TMEM259", "TMX2", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TPP1", "TPR", "TTYH3", "TUBGCP2", "TUBGCP4", "TWNK", "TXNDC16", "UGCG", "UGGT1", "UNC119B", "UQCRQ", "VDAC1", "VDAC2", "VKORC1L1", "VPS13A", "VPS25", "VPS52", "WASHC5", "XPO4", "XRCC5", "XRCC6", "YME1L1", "ZADH2", "ZFPL1", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_dto/advanced/idx2term.json b/pharos_dto/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f1bf5803851e0d97ca20356e3b2986b27bea88af --- /dev/null +++ b/pharos_dto/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter", "1": "SLC superfamily of solute carriers", "2": "SLC25 family of mitochondrial transporters", "3": "Intracellular calcium-sensing protein", "4": "Calmodulin", "5": "Calcium-binding protein", "6": "Mitochondrial nucleotide transporter subfamily", "7": "SNARE protein", "8": "ATP-binding cassette transporter family", "9": "Signaling"} \ No newline at end of file diff --git a/pharos_dto/advanced/plot_0.png b/pharos_dto/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..dcf70f53c1719ef9502bb3091453a83171d35cbf --- /dev/null +++ b/pharos_dto/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1923cae805ed786cf96758ab534b254b17b8f30ccc598a0b3489a5b16a6b4bb2 +size 219549 diff --git a/pharos_dto/advanced/plot_1.png b/pharos_dto/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..3227f3af92eae2bc2bacf1f7fae5371909377770 --- /dev/null +++ b/pharos_dto/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f1441745ba96b9d0e639e4792adcaa2f18bba2ae7d6458be4d5e6833694551e5 +size 210958 diff --git a/pharos_dto/advanced/plot_2.png b/pharos_dto/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9b1916ef881e4b41886d9dabff135a88a4786778 --- /dev/null +++ b/pharos_dto/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f634da923c67a505461404fec2e6f91df322ffe947387adbf61838fdacebc27e +size 197267 diff --git a/pharos_dto/advanced/plot_3.png b/pharos_dto/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..53cebb91155c272a9e22094ff3827ee3f5f697e9 --- /dev/null +++ b/pharos_dto/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c963533b07a572937e62c10b4b1c34bb7c03c9b8217c393d940e75d373e23be2 +size 198569 diff --git a/pharos_dto/advanced/plot_4.png b/pharos_dto/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ecf533b71fa1a551981cb6117400d5dbf75c64d7 --- /dev/null +++ b/pharos_dto/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:036e7307c9f079487eb759d963a431e038d48479a71e50e0bd73594ef4781d2f +size 194364 diff --git a/pharos_dto/advanced/plot_5.png b/pharos_dto/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..ff72e704d1f93b945769014b901ab2efca250ef9 --- /dev/null +++ b/pharos_dto/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0867acd0ad9b478db6d95b6ebf507f7fdab00e06a362dc2cc2466d66d12edb33 +size 199026 diff --git a/pharos_dto/advanced/plot_6.png b/pharos_dto/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..6ae89e50e20b5a9be2a47a4b8110e5599d64e1f2 --- /dev/null +++ b/pharos_dto/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6fa27fbb3e509267e42bea40b508eb68acd9408c70fd9bb80fb82e4f3dceb50e +size 193915 diff --git a/pharos_dto/advanced/plot_7.png b/pharos_dto/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..84798df89b3967fec3c1d96084e285a6a07bb847 --- /dev/null +++ b/pharos_dto/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b13e3d6862dd6acf9db0bec29b54888fd9971de49321bf24edd1b2fa1ac5fc8e +size 192072 diff --git a/pharos_dto/advanced/plot_8.png b/pharos_dto/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..d38458fd2780bd2719d53723af8b4485584a8fbf --- /dev/null +++ b/pharos_dto/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99a893f5a05aae0fc5d673a6be40fc1e5278baa1dc0492efd3164b6a06b90980 +size 193582 diff --git a/pharos_dto/advanced/plot_9.png b/pharos_dto/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c21011de72b03b4d8586210bc5d72eb9a0336884 --- /dev/null +++ b/pharos_dto/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53c1fcb8a11af723aecdff7fbb03ebdded8957a3a700f4bf4ccbd22e2ed59c84 +size 198345 diff --git a/pharos_dto/basic/idx2term.json b/pharos_dto/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8e1f29404933421909d8bcf4752a068fd586471f --- /dev/null +++ b/pharos_dto/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter", "1": "SLC superfamily of solute carriers", "2": "SLC25 family of mitochondrial transporters", "3": "Intracellular calcium-sensing protein", "4": "Calmodulin", "5": "Calcium-binding protein", "6": "Mitochondrial nucleotide transporter subfamily", "7": "SNARE protein", "8": "ATP-binding cassette transporter family", "9": "Signaling", "10": "Membrane trafficking regulatory protein", "11": "Extracellular structure", "12": "Oxidase", "13": "F-type and V-type ATPases", "14": "Receptor", "15": "P-type ATPases", "16": "Glycosyltransferase", "17": "Reductase", "18": "Small GTPase", "19": "Metalloprotease", "20": "Serine protease", "21": "DNA helicase", "22": "G-protein"} \ No newline at end of file diff --git a/pharos_dto/basic/plot_0.png b/pharos_dto/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0339c61f55e4311ea4d059cfce7e1fa26e7bd1f8 --- /dev/null +++ b/pharos_dto/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8e89aaa9fa0e65461d6ba530dc6411bec3fd0a5dcfb770f1cb60fd341a2c8ea +size 137909 diff --git a/pharos_dto/basic/plot_1.png b/pharos_dto/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8a68864873710273021f4e32d0fd57754ef8e5a5 --- /dev/null +++ b/pharos_dto/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4308a632e3921c7ff01409ed41b9ad79143c026f28aac5e1f3eb42dd60b80d4a +size 148921 diff --git a/pharos_dto/basic/plot_10.png b/pharos_dto/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..06fdf194745bd5e9a325ac569f8ddd8a9f8a428a --- /dev/null +++ b/pharos_dto/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:05475500f8564c04cf14ada1f9955ec7eeb892c7eec3f72127e4264b66cc24b0 +size 145378 diff --git a/pharos_dto/basic/plot_11.png b/pharos_dto/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..736f43e28d928e89955af73e34ce2230ea3f5634 --- /dev/null +++ b/pharos_dto/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2308d0ce171bb82b92b5223dea7861964b605e6a5fb005773e3c1d1e3d64297d +size 132721 diff --git a/pharos_dto/basic/plot_12.png b/pharos_dto/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..7d64ca3c6bc9318b2445c163cbf28120aa05dd86 --- /dev/null +++ b/pharos_dto/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94c43f196b6c800eb39dd96d7e02b9925a81d11bdf2fc2fb4835a3b5e6e212cd +size 131686 diff --git a/pharos_dto/basic/plot_13.png b/pharos_dto/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..e633cb67327ce8746c861a341fe0ccad8e379dfd --- /dev/null +++ b/pharos_dto/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4f2f74c755416a8644108c5e55ec7926ea518f299616770a2b177bfd287c44f +size 135878 diff --git a/pharos_dto/basic/plot_14.png b/pharos_dto/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..d2e11a7dbd58a88340063933fcbedbd21009b0ed --- /dev/null +++ b/pharos_dto/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e6070691623512e309de217973e177eecd930395290053934419565e77d3f16d +size 135493 diff --git a/pharos_dto/basic/plot_15.png b/pharos_dto/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..9f720681e2fc7194f3acd14dde5e073cdec92521 --- /dev/null +++ b/pharos_dto/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bad04a7026066db727d1679abe85db0c1aaaaf9cc5fe9970072d718893a7cbfb +size 130006 diff --git a/pharos_dto/basic/plot_16.png b/pharos_dto/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..6022bf064358062e63c4ef65f56270686d390023 --- /dev/null +++ b/pharos_dto/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60e2613b7797fbaeacec4fd9bec7c04289e14f041e729ed34f2733794486abf9 +size 129422 diff --git a/pharos_dto/basic/plot_17.png b/pharos_dto/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..bc9e70c80da2e9c3d57af8efb77356719fd3e432 --- /dev/null +++ b/pharos_dto/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:69f428ac7b69d0954b2b4b571025b1e5cfb485486730b5ff1a0adfbefd7756d7 +size 133699 diff --git a/pharos_dto/basic/plot_18.png b/pharos_dto/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..8de9fc45a3b96d18616afd9e06c567a0ae87cf3d --- /dev/null +++ b/pharos_dto/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6ed726c01f1375bc901c3ed425935abdbecbec48e94d7bec5f98a92164647a8 +size 142230 diff --git a/pharos_dto/basic/plot_19.png b/pharos_dto/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..4342dc6ad349290dfadd333b6e06f3182888dd32 --- /dev/null +++ b/pharos_dto/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3cbd551ee4214ea9bb5ed47f778095051d8edf28a889d738b4a0816243d5bc0a +size 146476 diff --git a/pharos_dto/basic/plot_2.png b/pharos_dto/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..318ab07dd00a710292cdcdad1670342fa6699f44 --- /dev/null +++ b/pharos_dto/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aa69f7c6f636dc197f77386be73f7577d229187b82ee403041b0810806cef473 +size 148016 diff --git a/pharos_dto/basic/plot_20.png b/pharos_dto/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..28f6153d4204d98cd71aa56f81b5ec0d1c7b1e21 --- /dev/null +++ b/pharos_dto/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38067c3f25e3a12d80162ae6769161e61faf121970e2aa309a21bf0d59f3eed3 +size 145091 diff --git a/pharos_dto/basic/plot_21.png b/pharos_dto/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..2456ca789c7f866dc25ea613480302bf710b97fe --- /dev/null +++ b/pharos_dto/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b77ae753e181186124ff4799c4019df360109efc2d75b919b69333ea3e80d6d7 +size 143161 diff --git a/pharos_dto/basic/plot_22.png b/pharos_dto/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..1090fb6a887ed0d6951d978c7f45bb118a32e8c8 --- /dev/null +++ b/pharos_dto/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b995372e5b884ded616b902b314eaa265351e028d0fc63e92758e778d39f536b +size 145288 diff --git a/pharos_dto/basic/plot_3.png b/pharos_dto/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..03f381839d31224951d1f5c255ba85f2782e703b --- /dev/null +++ b/pharos_dto/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:871199dbb4b55ff395a84ab50c6ae001f58d02e4105a46315ed4c87473e13ef7 +size 146587 diff --git a/pharos_dto/basic/plot_4.png b/pharos_dto/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..30f36d331f221dc0749108b483a00f7e918d248e --- /dev/null +++ b/pharos_dto/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:205b26240e765495e2406d98700f23f49be847457b9645336218c8235e37a529 +size 136980 diff --git a/pharos_dto/basic/plot_5.png b/pharos_dto/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..4f6f9001c934d5ba1f2416aa424d87b7663ed9a8 --- /dev/null +++ b/pharos_dto/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f69862af5ff2af26b7281b4b57d092573c0989eb8f2d0277681a3fb2c395cc7 +size 138960 diff --git a/pharos_dto/basic/plot_6.png b/pharos_dto/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..4f10318b484274f391b776490c402ef9fa947b1d --- /dev/null +++ b/pharos_dto/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e358c0e966c3153d51e78e6ade7610a6e881832e8b2a112decb0301285eec23d +size 148995 diff --git a/pharos_dto/basic/plot_7.png b/pharos_dto/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..01f7de5ae5fae9bb1ad574df1f28f8cb1447f26f --- /dev/null +++ b/pharos_dto/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4db19aa919ee354e0974b9f56767fbfed88b80f5807cf7983b34513bac638416 +size 136132 diff --git a/pharos_dto/basic/plot_8.png b/pharos_dto/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..43f17e5dbcd7081487615430c0c5e53698fafc5f --- /dev/null +++ b/pharos_dto/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:491d38b1192191bd3ce34ed108771ad7244e2d09e389ac20892a17299b7b905e +size 131265 diff --git a/pharos_dto/basic/plot_9.png b/pharos_dto/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..9b9d73c84d7e92dc1aff8e93cd0f0df8868dd798 --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62fe55b8988d76c7ed15fd7377bce03b63b320c2bc954d37c134adab08adabe3 +size 135739 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bb14ebed6d26febc55896bc0a9f50b68481c9ee7 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:763780e702f902b6fc829d8150cce51b6e27ae475d3f0995da37f8695bbc4714 +size 389575 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c30d3d153937fdffaf40b282a8e841a5baf47bdc --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,19 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter 98 218 6.992204471055697 2.706001032267155e-12 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 1.1988891305891317e-17 0.0073836807137422 0.0007615460005936 6.470587333054795e-09 6.938655048966678e-18 +SLC superfamily of solute carriers 33 50 3.977403134270087 6.967198990825985e-05 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 6.073381278967144e-06 0.2111338255209101 0.0979989328881401 0.0001337568188117 7.729418563255257e-06 +SLC25 family of mitochondrial transporters 14 21 3.777538800238275 0.0001583858356473 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 7.497573669284786e-09 0.1604648724397155 0.048990890514732 2.4880325513906888e-05 8.896897464501222e-09 +Intracellular calcium-sensing protein 8 14 3.459106778581645 0.0005419699996429 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 1.3008202003282518e-05 0.1403531442218371 0.0034893000144238 0.0009447024772989 1.4582817007597972e-05 +Calmodulin 8 14 3.459106778581645 0.0005419699996429 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 1.3008202003282518e-05 0.1403531442218371 0.0034893000144238 0.0009447024772989 1.4582817007597972e-05 +Calcium-binding protein 9 18 3.315592139561796 0.0009144918880181 6.135922330097087 18.021844660194176 1.3650952896045327 0.2072953623045914 2.3371152398743247 2.2037057261181348 1.237653756718734 0.2545563939054063 5.028942911729092e-05 0.019691222561341 0.0009611330378982 0.0007908116200209 5.671648619941003e-05 +Mitochondrial nucleotide transporter subfamily 8 9 2.945646143627344 0.0032228086054639 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 1.2636564597463718e-07 0.0683810764565047 0.1349531130589082 0.000371706641515 1.4106970997570562e-07 +SNARE protein 9 13 2.850114987329918 0.0043703426066059 4.555825242718447 10.6626213592233 0.9494792984446184 0.3117420251981136 2.5225757464631977 2.583604188764985 1.1633177546874711 0.3031193116521645 0.0002146879073638 1.0 0.2297987482657219 0.0038040834633598 0.000234374088003 +ATP-binding cassette transporter family 8 11 2.63609487308224 0.0083866279414057 2.2135922330097086 6.097087378640777 0.6703089129361733 0.3321717891455754 1.6917876191440782 1.952168637803411 1.1544628029909134 0.2803059295197611 0.0600064803273088 1.0 1.0 0.0762921742488627 0.0621142898948071 +Signaling 8 20 2.5544390924902016 0.0106359035884573 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.0598046404363514 1.0 0.5741114914523541 0.1646032801604304 0.0639136560040006 +Membrane trafficking regulatory protein 6 21 2.5202524458531874 0.0117270695116953 4.560679611650485 20.218446601941743 0.5159227056829229 0.4386866271320015 2.6094874555832708 2.7661001804550924 1.1256129588723178 0.3307884378613797 0.0216997319516657 0.1955113655682517 0.0720571885403784 0.3067990234802971 0.0063580922287898 +F-type ATPase 3 8 2.320038911960728 0.020338772443277 3.174757281553398 7.754854368932039 0.3978961134348252 0.300656405601223 2.006916121747128 0.8649601417133376 1.341428125637103 0.2766885427231999 0.0013168186836578 0.0506073598520519 0.1008375048293403 0.027832231049335 0.00138858926748 +Extracellular structure 6 8 2.139891525374183 0.0323635341504735 2.842233009708738 8.092233009708737 0.8560017356043709 0.3472532488838395 1.4285109580808126 1.0866524100509705 0.962827743376652 0.290186194394739 0.1263793020712777 1.0 1.0 0.4718643991127431 0.1303826157459173 +Oxidase 12 21 2.062343705100706 0.0391750248141482 6.703883495145631 19.237864077669904 1.0247065178117305 0.263154064152295 3.1321515397534676 1.9967748999180144 1.3264616190823058 0.2799417791483025 0.004326259109494 0.1444128696349771 0.0038117145357013 0.0449350347407693 0.0046379242911556 +F-type and V-type ATPases 5 17 2.053166446736417 0.0400564373783185 4.995145631067961 15.616504854368932 0.6819760311565471 0.3553057475304781 2.5561606009064737 1.187932616128487 1.149561543758102 0.2999604229905949 0.0005922430121995 0.1029565435856987 0.1993869387044997 0.1060727287920157 0.0006386483653524 +Receptor 8 31 2.0325272558945384 0.0421003073882209 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0677677672038472 1.0 0.6426690076912178 0.0143893569832829 0.0726847885070081 +ABCB subfamily 4 6 1.999553816629936 0.0455484651409383 1.4660194174757282 4.152912621359223 0.6118345866928353 0.3423864070958426 1.2012577064447347 1.3414295599134654 1.163285659538929 0.2820720534042253 0.3251899972986247 1.0 1.0 1.0 0.3290745839784397 +P-type ATPases 8 9 1.985173686106627 0.0471251508680656 3.2815533980582523 6.757281553398058 0.5021561418998097 0.3946150755400491 1.82441625577419 1.518277124105495 1.19746001211325 0.3286800838620415 0.0859119874297797 1.0 1.0 1.0 0.0888008652079453 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f14f90027196be07296d3e933668418b03e03f21 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 2231, + "title": "Average number of proteins per term", + "value": 3.1402958314657106 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..82e5004ec5a8db377415e2992c73c89c1c2263f0 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..62d56e1e9db7d26b0e8becb1f178dfa3b5df796f --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,67 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.5715143714845283 6.992204471055697 2.706001032267155e-12 6.037090515772961e-09 6.037090533988023e-09 218 Q9BQE5,P24390,Q8N1F7,O75027,O14678,P00846,Q9Y6C9,Q9HC07,P17900,Q9Y584,O43808,Q9H2D1,Q9P2W9,O15400,Q96ES6,Q86Y82,Q7L0J3,Q9UBX3,O43731,P49257,Q9Y3A6,Q9H2V7,O43493,Q9BSK2,Q12846,O43752,Q92544,Q70HW3,Q00765,P08183,P33527,Q12768,Q8NFH4,P24539,P33897,Q12907,Q9H2J7,P53985,Q9NP58,Q15070,Q8TAD4,O00400,P51572,O15439,P05023,P52292,Q6NUK4,Q8TB61,O60499,Q96A65,Q9H9B4,Q8N2H4,Q9C0E2,O75746,O95249,Q8N1S5,P12235,Q9Y619,Q9HD45,Q92973,Q15388,Q8N1B4,Q9NZJ7,Q9Y6M7,Q15363,Q9Y5J6,Q9UPT5,Q9BRK0,P12236,Q03518,O95202,P11279,Q9BQT8,Q99805,P30825,Q9H6H4,Q93050,O14653,P13473,Q8WVM8,O95721,P23634,Q7Z3B4,P56385,Q15043,P20020,P06576,P05141,P16615,Q9HC21,P49755,O43760,Q9Y487,Q9UI14,Q13190,Q6NUK1,O00560,Q99758 98 +SLC superfamily of solute carriers 0.6495570791086029 3.977403134270087 6.967198990825985e-05 0.1439646650811373 0.0777191047426649 50 Q9H2J7,Q9NZJ7,Q9UJS0,P53985,Q9Y6M7,Q8TAD4,Q9Y6C9,O00400,Q9HC07,P55011,Q8TB61,P12236,Q15043,Q9H2D1,O43808,Q9H9B4,Q96QD8,O95202,P05141,Q7L0J3,O75746,Q8N1S5,Q9HC21,Q9UBX3,Q9BQT8,Q9H2V7,P12235,Q6NUK1,Q9Y619,Q9BSK2,O95563,P30825,Q70HW3 33 +SLC25 family of mitochondrial transporters 0.7577332926540346 3.777538800238275 0.0001583858356473 0.2976945009564765 0.0808603774828126 21 Q6NUK1,Q9Y619,O75746,Q9BSK2,Q9HC21,Q9NZJ7,P12236,Q9H2D1,Q70HW3,Q9UBX3,Q9Y6C9,Q9BQT8,P05141,P12235 14 +Intracellular calcium-sensing protein 0.8079307543459465 3.459106778581645 0.0005419699996429 0.7016424994138846 0.0808603774828126 14 Q8IYU8,P80303,Q9BRK5,P41208,Q99584,Q14257,Q02818,O43852 8 +Calmodulin 0.8079307543459465 3.459106778581645 0.0005419699996429 0.7016424994138846 0.0808603774828126 14 Q8IYU8,P80303,Q9BRK5,P41208,Q99584,Q14257,Q02818,O43852 8 +Calcium-binding protein 0.7277495026283362 3.315592139561796 0.0009144918880181 0.8701226660311253 0.0808603774828126 18 P43307,Q8IYU8,P80303,Q9BRK5,Q99584,P41208,Q14257,Q02818,O43852 9 +Mitochondrial nucleotide transporter subfamily 0.8449152542372825 2.945646143627344 0.0032228086054639 0.999254680138846 0.0808603774828126 9 Q6NUK1,Q9BSK2,Q9HC21,P12236,Q9H2D1,Q70HW3,P05141,P12235 8 +SNARE protein 0.7289165336293787 2.850114987329918 0.0043703426066059 0.9999429511459136 0.0808603774828126 13 O95249,O43752,O14653,O60499,Q9P2W9,O15400,O95721,Q86Y82,Q13190 9 +ATP-binding cassette transporter family 0.7474074456459899 2.6360948730822393 0.0083866279414057 0.9999999930842725 0.0808603774828126 11 P33897,Q9NP58,Q99758,O75027,Q03518,P08183,P33527,O15439 8 +Signaling 0.5922558916248479 2.5544390924902016 0.0106359035884573 0.9999999999563924 0.0808843182935878 20 Q96PC5,O15173,O00264,Q99627,Q7Z4V5,P43490,Q8WUJ1,Q07820 8 +Membrane trafficking regulatory protein 0.5766042086760307 2.5202524458531874 0.0117270695116953 0.9999999999962816 0.0808843182935878 21 P24390,P13473,Q8WVM8,O43760,P11279,O43731 6 +F-type ATPase 0.7338955363544888 2.320038911960728 0.020338772443277 1.0 0.0969183295956108 8 P00846,P56385,P24539 3 +Extracellular structure 0.6991602337052154 2.139891525374183 0.0323635341504735 1.0 0.114426378272118 8 Q9BXS5,Q9Y2T2,Q5KU26,Q92791,Q32P28,O75718 6 +Oxidase 0.5165714980247124 2.062343705100706 0.0391750248141482 1.0 0.1262998271103536 21 O43169,O15260,O75880,O43819,O14548,O75845,P15954,P20674,Q15067,Q6ZRP7,P14406,Q15800 12 +F-type and V-type ATPases 0.5474944109189143 2.0531664467364172 0.0400564373783185 1.0 0.1278989911447862 17 P56385,Q93050,P00846,P06576,P24539 5 +Receptor 0.4565608633295877 2.0325272558945384 0.0421003073882209 1.0 0.1311186557276805 31 Q9GZP9,P57105,A6NIH7,Q9BUN8,Q9NR77,Q8WTV0,Q567V2,Q14108 8 +ABCB subfamily 0.7684930398786536 1.9995538166299356 0.0455484651409383 1.0 0.1376946148095304 6 Q9NP58,O75027,Q03518,P08183 4 +P-type ATPases 0.6587570621468823 1.985173686106627 0.0471251508680656 1.0 0.1401816154488727 9 P54709,P16615,Q04656,P20020,P05026,P23634,Q8NB49,P05023 8 +Phosphatase inhibitor 0.6584969145579542 1.7363324847184634 0.0825050625396575 1.0 0.1929662068681915 7 Q99733,Q01105 2 +Ca2+-ATPases 0.8030712822084141 1.6923496336151302 0.0905793295166814 1.0 0.202877272183277 4 P20020,P23634 2 +RSK family 0.9461516774739218 1.6813647420539932 0.0926920895687217 1.0 0.2055626757731792 2 Q15418 1 +RSK subfamily 0.9461516774739218 1.6813647420539932 0.0926920895687217 1.0 0.2055626757731792 2 Q15418 1 +Growth factor 0.6880140084669274 1.6207945174021134 0.1050617147253054 1.0 0.2236571427024393 6 Q7Z4V5,Q96PC5 2 +Mitochondrial amino acid transporter subfamily 0.7280923902355324 1.5883716257426743 0.1122023297105068 1.0 0.2325596402188131 5 Q9Y619,Q9UJS0,O75746 3 +Glycosyltransferase 0.4769142891322132 1.5831044389794755 0.1133976620361554 1.0 0.2340334727129165 18 Q9H3H5,P15291,Q10472,Q10471,Q9NYU2,Q16739,P04844,P04843,O60762,Q9BT22,P46977,Q8N128,Q8N4A0 13 +Lipid kinase 0.6783227671383949 1.5743831611486003 0.1153988943574091 1.0 0.2361971865242016 6 Q9BTU6,Q8TBX8 2 +Phosphatase modulator 0.571877971050308 1.501878924074301 0.1331283805872805 1.0 0.2577318448665968 9 Q99733,Q01105 2 +Oxygenase 0.6629287431577413 1.5003675616863814 0.1335192173703283 1.0 0.257824787381675 6 Q16850 1 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.7506522955992458 1.4680761670485265 0.1420835345788869 1.0 0.2686342081741497 4 Q9UBX3 1 +Extracellular matrix glycoprotein 0.7425766643874072 1.4333073999461683 0.1517700081647381 1.0 0.2807619305269742 4 Q9BXS5,Q32P28 2 +SLC39 family of metal ion transporters 0.8790527206089631 1.401602149634966 0.1610340847276898 1.0 0.289309686319019 2 Q8N1S5 1 +Aspartic protease 0.717300559757161 1.324251994717953 0.1854193678976883 1.0 0.3184531253115801 4 Q5BJF2,Q8TCT8 2 +Miscellaneous SLC25 mitochondrial transporters 0.8488863828587545 1.275887444318073 0.2019953100850497 1.0 0.3355558725240105 2 Q9NZJ7 1 +Galactosidase 0.8446574570059082 1.2583041951851133 0.2082817645546937 1.0 0.3434416975029724 2 P16278 1 +ABCC subfamily 0.8119537637439918 1.122927147570658 0.2614684366506798 1.0 0.3995452617586759 2 P33527 1 +Reductase 0.4186124303746512 1.1104630454733824 0.2667995439090682 1.0 0.4042408146681376 17 Q9UDW1,Q7LG56,Q14739,P00374,Q15392 5 +Small GTPase 0.3588555049940438 1.0178455565674918 0.308751358221397 1.0 0.442973813628255 26 O00429,Q9P0V9,O60313,P11233,O15397,O95373 6 +Esterase 0.4674166265426149 1.010058269886023 0.3124673736336869 1.0 0.4468684042158689 11 P50897,Q9UMR5 2 +Chloride channel family 0.7752397067117844 0.9644030270768122 0.3348439051826675 1.0 0.4642116711168697 3 P51797,P51790 2 +SLC35 family of nucleotide sugar transporters 0.7722018607273553 0.9606916312631244 0.3367072403088849 1.0 0.4660011495838227 2 Q8TB61 1 +SLC4 family of bicarbonate transporters 0.7507753030730009 0.8748904490938127 0.3816335163051145 1.0 0.5043983263487621 2 Q9Y6M7 1 +Hsp90 family chaperone 0.6064880112835016 0.8490538237278874 0.3958513431660586 1.0 0.5173663424742102 4 P14625,P07900,P08238 3 +PDHK family 0.7154540327129106 0.740372995039935 0.4590737001706859 1.0 0.5708993450840582 3 O14874,Q15118 2 +Metalloprotease 0.3159394805199493 0.7268836030596687 0.4672972626175575 1.0 0.5772647801216894 42 P02786,Q7Z2K6,O75844,Q10713,O15372,P55786,Q92905,Q9BYT8,Q5JRX3,Q9NZ08,P22695,Q96TA2,Q9NXS2,P42892,Q96E52,Q9UIQ6 16 +SLC56 Sideroflexins 0.7113053284465811 0.7213003175535786 0.4707247616477084 1.0 0.5783669441207197 2 Q9H9B4 1 +Serine protease 0.3214796403047807 0.7049070397652232 0.480868088898319 1.0 0.5871712224057342 30 P67812,Q9HB40,O14773,P10619,P42785 5 +Acyltransferase 0.3914953724794749 0.6483187185912959 0.5167788295799527 1.0 0.6162124900015363 12 Q9UJ14 1 +Ion channel 0.4176508365005725 0.6297696900053537 0.5288452791506912 1.0 0.6248491781185013 10 Q9C0H2,P51797,Q96RD7,P51790 4 +Na+/K+-ATPases 0.6841511562323658 0.6282673768641401 0.5298287989078498 1.0 0.6249144013118167 3 P05026,P05023 2 +Atypical group 0.4097179169549077 0.5571047272036379 0.5774558779466199 1.0 0.6574458909846097 8 P42345,Q15118 2 +SLC12 family of cation-coupled chloride transporters 0.6563292923597488 0.5215167804666128 0.6020068190271772 1.0 0.6712030051222551 2 P55011 1 +Kinase activator 0.3984795352806259 0.4996651054599858 0.6173109067028202 1.0 0.680940123573236 8 Q9Y3A3 1 +Lipase 0.3783861872565576 0.4230629644858613 0.6722493226438786 1.0 0.7145251256877052 9 Q6PIU2,Q8N2A8,Q8NCC3 3 +Protease inhibitor 0.3588789818378876 0.3858260688823456 0.6996254871916845 1.0 0.7296699147348837 11 P05067,Q06481,P27105 3 +Phospholipase 0.3787884276643849 0.3160586573123317 0.7519579861256367 1.0 0.7695496637827044 7 Q8NCC3 1 +AGC group 0.3242036766052152 0.3151257456793922 0.7526661814088602 1.0 0.7699212520509707 13 Q15418 1 +DNA helicase 0.3265479219677635 0.2834476263729389 0.7768337240606455 1.0 0.7935512996242218 12 O60264,P25205,P12956,P33993,P13010,P49736,Q9H4L7,Q14566,Q96RR1,P28370,P33991 11 +Chromodomain 0.4529090474615432 0.2731567968952277 0.7847326885434072 1.0 0.8012533767232684 4 P45973 1 +G-protein 0.2634294708153029 0.2246044256043843 0.8222870217185054 1.0 0.8369171284005409 36 P55060,P50570,Q8NHH9,O00429,Q9P0V9,Q9UI26,P11233,O60313,O15397,P29992,Q9NTK5,O95373,Q96P70 13 +TK group 0.3896726862302464 0.1734054973475071 0.8623327043070854 1.0 0.8756778622253562 5 P41240,P07947,Q15375,Q13308 4 +Cadherin 0.5049337468283175 0.1241804424328527 0.901172407045931 1.0 0.910972197607373 2 Q14574 1 +CDK1 subfamily 0.4722300535664025 0.0772649531165904 0.938412770893774 1.0 0.9469013531723246 2 P06493 1 +KRAB box transcription factor 0.447264523406661 0.0478063735348973 0.9618705570198732 1.0 0.9692561936365568 3 Q7Z3K3,O95785 2 +C2H2 zinc finger transcription factor 0.447264523406661 0.0478063735348973 0.9618705570198732 1.0 0.9692561936365568 3 Q7Z3K3,O95785 2 +V-type ATPase 0.2788031690573916 0.0292547393375445 0.9766614242133054 1.0 0.9837163148622502 9 Q93050 1 +CDK4 subfamily 0.3532562729066874 0.0039689353070642 0.9968332561096648 1.0 1.0 2 P11802 1 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eed77f57f16cd92cdb704237072d8cc4b0e904f6 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit beta-1", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCA subfamily", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AMSH-like protease", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family A member 3", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 6, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 1", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 2B", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldolase", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Alpha-tocopherol transfer protein-like", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Ankyrin repeat and SAM domain-containing protein 1A", "Ankyrin repeat and SOCS box protein 6", "Annexin", "Antibacterial response protein", "Antigen peptide transporter 1", "Ap2-associated protein kinase 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BTB/POZ domain-containing protein KCTD21", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 1", "Beta-adducin", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biogenesis of lysosome-related organelles complex 1 subunit 1", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-3", "Caspase-7", "Caspase-8", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere-associated protein E", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Chloride transport protein 6", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-6/CLCN6 subfamily", "ClC-7/CLCN7 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Copper-transporting ATPase 1", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 6", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyribose-phosphate aldolase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Deubiquitinating protein VCIP135", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Down syndrome critical region protein 3", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity protein kinase clk3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase DTX3L", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ETS-related transcription factor Elf-2", "Early endosome antigen 1", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Ephrin-B1", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAD-dependent oxidoreductase domain-containing protein 2", "FAK family", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Focal adhesion kinase 1", "Folate transporter 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-1", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Gamma-tubulin complex component 4", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutaminyl-peptide cyclotransferase-like protein", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glycylpeptide N-tetradecanoyltransferase 2", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Heat shock factor protein 1", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Hepatoma-derived growth factor-related protein 3", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase 3", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Homeobox protein CDX-2", "Homeodomain transcription factor", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "IRAK family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Interleukin-1 receptor-associated kinase 1", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF13B", "Kinesin-like protein KIF14", "Kinesin-like protein KIF15", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIF7", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase inducer phosphatase 3", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MAPKAPK family", "MAPKAPK subfamily", "MARK subfamily", "MAST family", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MSN subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Map kinase-activated protein kinase 3", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 20", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Membrane-bound signaling molecule", "Metal-response element-binding transcription factor 2", "Metalloendopeptidase OMA1, mitochondrial", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Metastasis-associated protein MTA3", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 4", "Mitogen-activated protein kinase kinase kinase 7", "Mitogen-activated protein kinase kinase kinase kinase 4", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 5", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 1", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear factor related to kappa-B-binding protein", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 4", "Obg-like ATPase 1", "Occludin", "Opioid growth factor receptor", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 3", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal leader peptide-processing protease", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipase DDHD2", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylase b kinase regulatory subunit beta", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable asparagine--tRNA ligase, mitochondrial", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein Hook homolog 2", "Protein Hook homolog 3", "Protein LSM14 homolog A", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein SYS1 homolog", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase c alpha type", "Protein kinase c beta type", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein lin-9 homolog", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec24D", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rab5 GDP/GTP exchange factor", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "Ral GTPase-activating protein subunit alpha-1", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinoblastoma-associated protein", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Riboflavin kinase", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE11 family", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 1", "Sentrin-specific protease 3", "Sentrin-specific protease 6", "Separin", "Septin-10", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine-protein kinase atm", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase smg1", "Serine/threonine-protein kinase tousled-like 2", "Serine/threonine-protein kinase ulk3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TATA box-binding protein-like protein 1", "TATA-binding protein-associated factor 2N", "TATA-binding transcription factor", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TLK family", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 6", "Transcription initiation factor TFIID subunit 7", "Transcriptional activator protein Pur-alpha", "Transcriptional activator protein Pur-beta", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone C", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tubulin-specific chaperone cofactor E-like protein", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type II pantothenate kinase family", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "Tyrosine-protein phosphatase non-receptor type 9", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "UDP-glucose:glycoprotein glucosyltransferase 1", "ULK family", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-Ie", "Unconventional myosin-VI", "Unconventional myosin-Va", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit G 1", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 52 homolog", "Vacuolar protein sorting-associated protein 72 homolog", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "ZZ-type zinc finger-containing protein 3", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "Zinc finger and BTB domain-containing protein 10", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein-like 1", "Zinc finger transcription factor", "Zinc transporter 5", "Zinc transporter ZIP11", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASB6", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BLMH", "BLOC1S1", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDX2", "CEBPZ", "CENPE", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCTD", "DCTN1", "DCTN2", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDT", "DENR", "DERA", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK6", "DOCK7", "DOLPP1", "DPAGT1", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "ENPP1", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC4", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F2", "GTF2H1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDGFL3", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HOOK3", "HPRT1", "HSD17B10", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITCH", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD21", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRRFIP1", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS2", "MASTL", "MAT2A", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED20", "MED21", "MED25", "METTL1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL38", "MRPL39", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS16", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NARS2", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4", "NEDD4L", "NEK9", "NFRKB", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGFR", "OLA1", "OMA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "P3H1", "P3H4", "PACSIN2", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD5", "PDCD6IP", "PDE12", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN9", "PTPRF", "PUDP", "PUM1", "PURA", "PURB", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RALGAPA1", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNGTT", "RNH1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT1", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMG1", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPHK2", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAMBP", "STAMBPL1", "STAT1", "STAT3", "STK26", "STOM", "STOML2", "STRBP", "STT3A", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TAP1", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBCEL", "TBPL1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM165", "TMEM259", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRMT6", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSPYL1", "TST", "TTK", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "ULK3", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP36", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VCPIP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS52", "VPS72", "VRK1", "VRK3", "WARS", "WASHC5", "WDHD1", "WDR1", "WDR4", "WDR82", "WIZ", "WNK1", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFPL1", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ACOX1", "ALG1", "AP1M1", "AP3M1", "APLP2", "APOL2", "APP", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP7A", "B4GALT1", "BCAP31", "BCKDK", "CALU", "CBX5", "CDK1", "CDK4", "CETN2", "CLCN3", "CLCN6", "COLEC12", "COPS5", "COPS8", "COX5A", "COX7A2", "COX7A2L", "COX7C", "CRTAP", "CSE1L", "CSK", "CTSA", "CYB5B", "CYB5D2", "CYP51A1", "DERL1", "DERL2", "DHCR24", "DHFR", "DNM1L", "DNM2", "DPAGT1", "DPM1", "DSC3", "ECE1", "EIF3H", "EPHA7", "ERAP1", "ERMP1", "EXOC4", "EXOC7", "FAM177A1", "GALNT1", "GALNT2", "GALNT4", "GGT7", "GLB1", "GM2A", "GNA11", "GOSR1", "GOSR2", "HDGFL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "IPO11", "IPO7", "IPO8", "IPO9", "KDELR1", "KDELR3", "KPNA2", "LAMP1", "LAMP2", "LBR", "LETM1", "LMAN1", "LMAN2", "LNPEP", "MCL1", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "MFSD3", "MIA2", "MICU2", "MOB4", "MPC2", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "MTOR", "NAMPT", "NAP1L4", "NCEH1", "NLN", "NPEPPS", "NUCB1", "NUCB2", "NUP37", "NUP54", "NUP93", "OLA1", "OMA1", "OPA1", "OXA1L", "P3H1", "P3H4", "PANX1", "PDK1", "PGRMC1", "PGRMC2", "PI4K2A", "PIP4K2C", "PITRM1", "PLA2G15", "PLD6", "PMPCA", "POGZ", "PPT1", "PPT2", "PRCP", "PTK7", "PXMP2", "QPCTL", "QSOX2", "RABAC1", "RALA", "RCN2", "REEP2", "REEP3", "REEP4", "REEP5", "RPN1", "RPN2", "RPS6KA1", "RRM2B", "S100A13", "SC5D", "SCARB1", "SCARB2", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SEC11A", "SEPT10", "SET", "SFXN1", "SLC12A2", "SLC16A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC4A7", "SLC6A15", "SLC7A1", "SMARCA1", "SMARCA5", "SMARCAD1", "SNAP29", "SPNS1", "SPPL2A", "SSR1", "STOM", "STT3A", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SURF4", "SV2A", "SYNGR2", "SYNJ2BP", "SYS1", "TAP1", "TFRC", "TGOLN2", "TIMM10B", "TIMM22", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMEM165", "TMEM97", "TNPO1", "TOMM20", "TPP1", "TTYH3", "TWNK", "UGCG", "UGGT1", "UNC119B", "UQCR10", "UQCRC2", "VPS52", "WASHC5", "WIZ", "XPO4", "XRCC5", "XRCC6", "YES1", "YME1L1", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5caa491b9aa6e04692523f9ba93639712ee5eb71 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b1aee29e49897f1b42f4d471c229d81262d0aafb --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1fee9785772d81add79771a9d9ef736ed812057103743a61d15e899728979fd0 +size 206753 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5caa491b9aa6e04692523f9ba93639712ee5eb71 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2734af4ddbe57bff5470dcfdad09d9a9b2e8d323 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:76fa889cf0a50327d6746802ba91ac4a1ab46a4cd394115bb01db4f989e30e8b +size 132040 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d362d3a6a9ce85275ffa7ed1ae5b899aa35d6247 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3a02bc158801b630b517dac421960bd9e52a8bea008cf9399674ee23c3c229e +size 80063 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fb9a0228adc8e2ca5c2d0587e3d2406ebe7d4d53 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tdark 97 381 2.2704937655495856 0.0231776411376241 74.3131067961165 324.373786407767 0.5859664552431031 0.6577158703271868 20.515717939687796 49.369088361677456 1.229854636263473 0.4013924214985833 0.9999138074104372 0.7928065221471793 0.5425558692075431 0.8292407680770432 0.999872555800102 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2720111f12b3c199c2539329a429bd0839803e24 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 887.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..54c6d2db74b0a88e7efa4095aab972b0e68f581e --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..90182f5db5c178aa0d78bda7904525b92d826e43 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tdark 0.3468883509249907 2.2704937655495856 0.0231776411376241 0.0895368620690776 0.0927105645504964 381 O60830,Q8N4H5,Q6PI78,Q9NUQ9,Q8NBN7,Q6UW02,Q70UQ0,Q9Y4Y9,Q5SNT2,Q9P2K2,Q69YU5,Q9NX00,O75964,Q8IW92,Q15005,Q15006,Q9BRJ2,Q6ZXV5,Q9H1Z9,Q96ES6,Q96CN7,Q86YN1,Q9Y6X3,Q9NW68,Q9H1E5,Q9NR33,Q96CP7,Q5VW38,Q9H4I3,Q8NBN3,Q3SXM5,Q8WWC4,O43731,P14406,O95302,P62312,Q9NRY5,Q9BSJ2,Q9Y5M8,O95070,Q8WVI0,Q9P0S9,Q96A49,O75071,Q8NFH4,Q9H330,Q96IX5,Q96M27,Q8N4V1,Q9BTE7,Q15629,Q8N8L6,Q96LJ7,Q9BWH2,Q96EX1,Q96B49,Q9NR77,Q8N2H4,Q9HD20,Q9NX62,O60476,Q96J42,Q8WVC6,Q8NBM8,Q9NPA0,Q9HD45,Q8TCD1,L0R6Q1,Q969T7,Q6YN16,Q7Z4Q2,Q9Y5J6,Q9BRK0,Q7Z3D4,Q9NPL8,O43615,O94919,Q7Z6M1,Q8IYS2,Q99805,Q8N128,Q9NPR9,Q9Y3C0,Q9BVG4,Q6NUQ4,Q6UX07,Q8IZ07,Q8WUJ1,Q7Z2K6,Q6UW68,Q9NWR8,Q96DB5,O75935,Q9Y6J9,Q9Y320,Q86YQ8,Q92564 97 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..09c45626757879cd3bb0086a30a5e6297d944596 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKS1A", "ANLN", "ANO10", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG2B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf198", "C1orf35", "C2CD2", "C2CD5", "C5orf22", "C5orf51", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CENPH", "CENPI", "CENPK", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG1", "COG3", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM160B2", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FOXRED2", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD3", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLHDC4", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL9", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OTUD4", "OTUD6B", "OTULIN", "OXA1L", "OXNAD1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "SYVN1", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM41A", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UHRF1BP1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFPL1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF106", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ANKRD13A", "ARL10", "ATP13A1", "ATP5L", "BSDC1", "C12orf73", "C18orf32", "COX7A2", "CPNE8", "CYB5D2", "CYP20A1", "DCAKD", "DCTN3", "DCUN1D4", "DCUN1D5", "DHRS1", "DHRS13", "DOLPP1", "EFCAB14", "EMC2", "EMC7", "ENDOD1", "ERMP1", "FAM114A2", "FAM177A1", "FAM49B", "FKBP9", "FUNDC2", "GLB1L2", "GPR107", "GPR108", "HEATR3", "HSDL1", "HSDL2", "IKBIP", "IMPAD1", "ISOC1", "KDELR3", "KIAA2013", "LSM5", "LSM6", "LYSMD3", "MAIP1", "MAN1A2", "MAU2", "MCUB", "MFSD3", "MMGT1", "MRPL45", "NT5C3B", "NUP37", "PBDC1", "PCYOX1L", "POLE4", "PRRC1", "PXMP2", "RABEPK", "RDH13", "REEP2", "RMDN1", "SLC35A4", "SMIM12", "SMIM4", "SPCS2", "SRPRB", "SYAP1", "SYS1", "TAF6L", "TIMM10B", "TIMM17B", "TIMM44", "TIMMDC1", "TLCD1", "TM9SF2", "TM9SF3", "TMEM14C", "TMEM160", "TMEM201", "TMEM205", "TMEM214", "TMEM245", "TMEM65", "TMEM87A", "TMTC3", "TMX2", "TMX4", "TOMM5", "TOMM6", "TRABD", "TRAM1", "TSPAN10", "TUBGCP2", "TXNDC15", "TXNDC16", "USMG5", "WASHC3", "YIF1A"]} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/idx2term.json b/protein_atlas_biological_process/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..05465cd122d8249d1ea07531bd35ccbcc4ae2adb --- /dev/null +++ b/protein_atlas_biological_process/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Protein transport", "2": "Sphingolipid metabolism", "3": "Translocation", "4": "Respiratory chain", "5": "Ion transport", "6": "Lipid transport", "7": "ER-Golgi transport", "8": "Calcium transport", "9": "Electron transport"} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/plot_0.png b/protein_atlas_biological_process/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b048103f1cb28ef8193532c8bcd602fadb354da8 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2932275494b729cedbe16d98e4b9790c04fff484a648f670f17aeb4e6fc8d468 +size 221538 diff --git a/protein_atlas_biological_process/advanced/plot_1.png b/protein_atlas_biological_process/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7cf4da771f855952796316bc07d9ee86e9391eef --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c322c7d2f6f5ddd453f49e887b91e7cec7b597219c3bc4ee4590a64c74638dea +size 214300 diff --git a/protein_atlas_biological_process/advanced/plot_2.png b/protein_atlas_biological_process/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..cb6c7814ffecfbe766a7648558af7a9d518fd171 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5a23e6ae2d0cec4a9964440ab3a95373ca96c5b6d2c222f3acbce0c638fc17d +size 195428 diff --git a/protein_atlas_biological_process/advanced/plot_3.png b/protein_atlas_biological_process/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..72136d0966fa1093885e4adcb06fbe36d53079c7 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d2cfea58698b00f2776b159e89e39f48a0fdd734b9138e829aef088b795d936 +size 199760 diff --git a/protein_atlas_biological_process/advanced/plot_4.png b/protein_atlas_biological_process/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..1fd30e56ea374ccdff8464c283ece25d6a018ce7 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7df683f48f93ba8e47875db690f92c041d87f67f019abf8d03c87ba544cfec01 +size 204747 diff --git a/protein_atlas_biological_process/advanced/plot_5.png b/protein_atlas_biological_process/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..51221e2edc35f1919036ab5d3697ad6dfc0e38e6 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:642be85b4366127905dd52315bc31ff1228df18148980b5ab97848c9d3a47bde +size 206967 diff --git a/protein_atlas_biological_process/advanced/plot_6.png b/protein_atlas_biological_process/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..a620d9c1ef850bb9f82d6db29cd59f0a927d248c --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d84faf333951fa9542317c7aa59d8220a671568205fc2672492de8b2f79670fb +size 201962 diff --git a/protein_atlas_biological_process/advanced/plot_7.png b/protein_atlas_biological_process/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..248dbdc3b27b8e977dcbcd559c2d5f8bb1a312c8 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:09b58b49e28088da3467ecef41b6d046dfacb85b64b9d7cbd3b1c9099383fa4d +size 207662 diff --git a/protein_atlas_biological_process/advanced/plot_8.png b/protein_atlas_biological_process/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..570ec711b5a68cf9a2c52bc1c16f77c6b064ae41 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f83fce3964ead58f5290545718086100f7e4f52213c279de711d341de682113a +size 187915 diff --git a/protein_atlas_biological_process/advanced/plot_9.png b/protein_atlas_biological_process/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..3ed99237d7631b8d4437a4ae0417f8ebbb8e7508 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d3d36e70e7d78451eaf2f7ba5370dcb5a9897ecfb4fae3ae063573e0bc43f8cd +size 207929 diff --git a/protein_atlas_biological_process/basic/idx2term.json b/protein_atlas_biological_process/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fa67199270f935ad3f8d1607660d4e281945bfae --- /dev/null +++ b/protein_atlas_biological_process/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Protein transport", "2": "Sphingolipid metabolism", "3": "Translocation", "4": "Respiratory chain", "5": "Ion transport", "6": "Lipid transport", "7": "ER-Golgi transport", "8": "Calcium transport", "9": "Electron transport", "10": "Sterol metabolism", "11": "Antiport", "12": "Hydrogen ion transport", "13": "Cholesterol metabolism", "14": "Steroid metabolism", "15": "Steroid biosynthesis", "16": "Symport", "17": "Sterol biosynthesis", "18": "Adaptive immunity", "19": "Sodium transport", "20": "Phospholipid metabolism", "21": "Amino-acid transport", "22": "Cholesterol biosynthesis", "23": "Phospholipid biosynthesis", "24": "Apoptosis", "25": "Exocytosis", "26": "Cell adhesion", "27": "Cilium biogenesis/degradation", "28": "Stress response", "29": "Lipid metabolism", "30": "Autophagy"} \ No newline at end of file diff --git a/protein_atlas_biological_process/basic/plot_0.png b/protein_atlas_biological_process/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3b430ccd141b151825ca100376bebdfd9120b7cb --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd2912db1adaa1781b821121676c8a9107e5a2b099338cf2ef1647ca44c42836 +size 139481 diff --git a/protein_atlas_biological_process/basic/plot_1.png b/protein_atlas_biological_process/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4c10c8c60a24755a1fbbb062f08d77eb02054960 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89b0f201a6ce49a76cbd03a22722583a4da115de90a8e2c92ca034e6385e3e33 +size 146161 diff --git a/protein_atlas_biological_process/basic/plot_10.png b/protein_atlas_biological_process/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..f137c27f2d77a97d15ffe537697c218ca7836a3a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be059a3459d419ede9cd1143828cac0fe1372a156f5df292309e7faeaff88006 +size 137084 diff --git a/protein_atlas_biological_process/basic/plot_11.png b/protein_atlas_biological_process/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..f54f19d8b09758d0ffe33a9a4a3914a46e21d1d0 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f9eb34a1a79ceecd6e7d7d1e0dc5651cd7c7f6ca5c3817056679f9d61deed701 +size 128653 diff --git a/protein_atlas_biological_process/basic/plot_12.png b/protein_atlas_biological_process/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..369cd6666b23a577b3b8c3ccefa646b90f10aa07 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dca1e7cdc4ebd5e25c7f54e76a25282e0ab9959aedfc8ed83d106cd218e891c7 +size 133615 diff --git a/protein_atlas_biological_process/basic/plot_13.png b/protein_atlas_biological_process/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..30897ebce65ddeacf0d20048303187b7c740e353 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0bf54641c9ac3a3af7aa5bb8f8b5437efa27a84e96154860efaff543f893a28e +size 139023 diff --git a/protein_atlas_biological_process/basic/plot_14.png b/protein_atlas_biological_process/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..579627c07b7babe762f6ded3157e9d77804af834 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ca6b01dde400e53251e7447f2e5fbfc409a70191196a8ae98c3a342288699c2 +size 136098 diff --git a/protein_atlas_biological_process/basic/plot_15.png b/protein_atlas_biological_process/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..28fad2f5db77c7ad92947b91d579b24359d1c886 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:61b59b0a5aeaaf2bc187479b733f71a7c964ec01f7c87d1b5620a9707bd255a6 +size 135302 diff --git a/protein_atlas_biological_process/basic/plot_16.png b/protein_atlas_biological_process/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..a594825e8d11bd8ff806c0e23e49bcfb1a3487f4 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c23bb40e6bb0c5e3805f9f6aa449c08b2384e58e6c724c437d3fcb7d41741ee1 +size 128694 diff --git a/protein_atlas_biological_process/basic/plot_17.png b/protein_atlas_biological_process/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..7c492bdda24dfaeacc5f303e63bfac121022c67f --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2dd8b4df22051de6a17770049834a1b1445992191c7b00be3474e8c618b5935e +size 132130 diff --git a/protein_atlas_biological_process/basic/plot_18.png b/protein_atlas_biological_process/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..791ea428d747764e3f0e09007fcf56374a37db1a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:22748a7d3495e6cb7f3cb271b31a27c981a4f7bf88958bc88e1ac70916b0669f +size 135242 diff --git a/protein_atlas_biological_process/basic/plot_19.png b/protein_atlas_biological_process/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..bdfc19c33a094669f49cb6447e2c55bfbecc52ab --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a6aecbbb44549d89077f698a14aa242ad8aae15e5f6f734b51df67b84642b41 +size 133235 diff --git a/protein_atlas_biological_process/basic/plot_2.png b/protein_atlas_biological_process/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..4f8b4c2df244dd77a3a982fe2eb895ed888fd2e0 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53e75941733afe110924c199e8b50350638b35a032e2e380f00bef471369325f +size 142656 diff --git a/protein_atlas_biological_process/basic/plot_20.png b/protein_atlas_biological_process/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..b3538ac6bccab535fd2eb8782ac82bf484b9cb8a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:248e4d8da8cf48ad4955d21b0a0e81ce46c5ac988a06fc7b7e13e31590ba8b9a +size 134081 diff --git a/protein_atlas_biological_process/basic/plot_21.png b/protein_atlas_biological_process/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..b46ea31c065d67ecc5bd6731f05b28d556d3a352 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:afd9cab5d48cf07e9502fd0a27211c5662be9a5b3f6d32e2d7bf621e31113735 +size 134446 diff --git a/protein_atlas_biological_process/basic/plot_22.png b/protein_atlas_biological_process/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..e7ae6d287553899eafe24df0602b0897a475987d --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0242b659e93ac14576888b18d21e1083a3a70ffc5533a39a324bdc516b374f72 +size 136923 diff --git a/protein_atlas_biological_process/basic/plot_23.png b/protein_atlas_biological_process/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..99eb105cb47ab5d4e69b8f50c46c1dd6a06eea05 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1487e78aba8e9486edf3a5640d4d1e08ec436e02834e9b7cb15e35974c424517 +size 134830 diff --git a/protein_atlas_biological_process/basic/plot_24.png b/protein_atlas_biological_process/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..7ba656e80fce27d2432faef95382fed856e920fb --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5000891ba504b1f59b8425c6857e49b1813226f6a6fd0e716af6c80463791b5d +size 138410 diff --git a/protein_atlas_biological_process/basic/plot_25.png b/protein_atlas_biological_process/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..1250be34926aa926a022718fd11a9baf849e0e96 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:44437fd62697036f3a5dfadb14f3ef51c9abc3685570d7d9be95f010cd0bfeaa +size 135465 diff --git a/protein_atlas_biological_process/basic/plot_26.png b/protein_atlas_biological_process/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..49f8eeddfb075cd7121b7ae0cbbad7a924310331 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:062ccabe7cb79a86fce9221dd971fec6d042ab29463aab29db550e271956e1ab +size 146848 diff --git a/protein_atlas_biological_process/basic/plot_27.png b/protein_atlas_biological_process/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..801875b3e317327bb3743d72984016f3ded5f313 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6e04c448c7ba7c3cc38c49fa0437aef283aa09b4a3a333b5acf0f0e0ddbdaf04 +size 155183 diff --git a/protein_atlas_biological_process/basic/plot_28.png b/protein_atlas_biological_process/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..8917ce225729ec281f81b11646506de9a8cda490 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:45d43a6c1803edac0b8ddcdabbe099113a9973be1ff62a9d7dfb505f78c34d1e +size 147657 diff --git a/protein_atlas_biological_process/basic/plot_29.png b/protein_atlas_biological_process/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..88f129e2112df497075a7c92e135d2c8034363d2 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b9246929b5e40148290e809b323f1906694b04aed9ec8c0327f30eb05805da31 +size 137312 diff --git a/protein_atlas_biological_process/basic/plot_3.png b/protein_atlas_biological_process/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..32eda94a024fec08a25e9c4346f13fc14bc4d5b4 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8084c157a9243c12c3e5e301c498480590d117fe44d72ad37661fe3d3824cdd8 +size 139104 diff --git a/protein_atlas_biological_process/basic/plot_30.png b/protein_atlas_biological_process/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..9c77643e97b772130bab8e02b8284ec06deff78e --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:364302122e213ec3b03516858b09ddde4f8e503e7324edecdf73ce0acc9cba02 +size 149353 diff --git a/protein_atlas_biological_process/basic/plot_4.png b/protein_atlas_biological_process/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..33c612f736e253655f7a4b383fba1fea77887d99 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f95ba9b3b6071d9019d940100da88d7fcf678c8e0fc01aa9a767ffdf06b64f3d +size 139062 diff --git a/protein_atlas_biological_process/basic/plot_5.png b/protein_atlas_biological_process/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..8701e176aa1df4ca4432d5d42fc8e37033dba73e --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50fec83702c940f305b1e58876a6b21973848edc09954256c4bd2e2854e5622c +size 136535 diff --git a/protein_atlas_biological_process/basic/plot_6.png b/protein_atlas_biological_process/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..8396e9d0326794930bacf866fba35bcae079c71b --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b8acf3b4f7eb8d684b13597383f3cf85d78a729fc48511d1a307089edc33a4a0 +size 135836 diff --git a/protein_atlas_biological_process/basic/plot_7.png b/protein_atlas_biological_process/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..d504e19169ed7e5ebcf58692abff3658703451ce --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5d2b63f8d4ba31014ed0b800e2a96494d17a28c7a49d1b8ab8d3f9e427f1c0e +size 145860 diff --git a/protein_atlas_biological_process/basic/plot_8.png b/protein_atlas_biological_process/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..97e87650d7b4624ec4e43abbd2c05bbd238d0d82 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e14aa29dc1066ee7d9c670a893284f362534dc8e6774dfd3980045922c51d625 +size 137022 diff --git a/protein_atlas_biological_process/basic/plot_9.png b/protein_atlas_biological_process/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..01a3c3751e9c064f61fd2e70499f2c760e5a1231 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5ac1ce2c7f4244b163424e6c0ec170607c61108343465b12e8e4d34143d828fb +size 137440 diff --git a/protein_atlas_biological_process/consensus.joblib b/protein_atlas_biological_process/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..54a7f0eaef403da0b13d1706061c17dfd86f5274 --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a1037471fd0f30a8b796e91038d6dd52c1fb5d8bb866e72ec3c13563e2f679fd +size 105804 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..265821c8530c873cde19e64df8ed91ae0b9e0f72 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,22 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport 222 568 5.026118185498186 5.005075037025381e-07 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 4.11170582513029e-27 6.665390002723369e-05 4.166358878325683e-07 4.131477909741522e-16 6.0661367723319345e-27 +Protein transport 90 291 3.891620930048359 9.957673640093034e-05 60.970873786407765 250.03155339805824 0.5647835050770387 0.6753991045983436 18.49610628700502 28.95320084782557 1.0712917387948182 0.3856428267622117 1.1356075244304613e-08 0.0443111453199642 0.0066591229803417 1.0711781718948665e-05 1.909262668353475e-08 +Sphingolipid metabolism 9 12 3.1923566063379227 0.0014111699219885 5.075242718446602 9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 3.6768645946089867e-09 0.0035263772514821 0.0007461625149634 3.960684957731953e-06 4.219224612343862e-09 +Translocation 23 53 3.098472706986586 0.0019452088625175 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 3.130233516015562e-07 0.0003907011914147 7.389910731518841e-05 6.954749025761443e-05 3.792852772303437e-07 +Respiratory chain 10 34 3.0417422782672503 0.0023521318900907 10.895631067961164 31.91990291262136 1.1075564231308468 0.3095707256998049 4.44287149555612 3.6670789399383112 1.4970961025113558 0.3356221172021658 0.0001304358112227 0.0029102285656399 0.0002876902013005 1.4349197272756235e-05 0.0001478886096126 +Ion transport 30 66 2.9783734561954938 0.0028978266209294 19.82766990291262 54.68446601941748 1.177785596906995 0.303722365376275 8.99659651977233 7.41832233515522 1.8666057057567336 0.3607289685223158 1.235592947500886e-07 0.0613334145365403 0.1133516249606659 0.0024550461314895 4.540176248016361e-08 +Lipid transport 9 28 2.831695065227066 0.0046301981829106 5.140776699029126 21.796116504854368 0.7022879686929654 0.35525802853007 2.5598823127228028 3.5727100026626353 1.209238263022456 0.2984698606617377 0.0009756192602542 0.2648597161900051 0.1290920553826253 0.0723728978816966 0.0010872803465048 +ER-Golgi transport 20 55 2.673966379825771 0.0074959965951491 13.189320388349516 50.09466019417476 1.0113245710455496 0.4417664900586612 5.844513029144237 4.526971021787617 1.2802141654412966 0.393016134031976 2.667786680594681e-05 0.0555854025812291 0.0075904072731156 0.0034072506264547 3.1223026356234384e-05 +Calcium transport 7 11 2.6453378709758804 0.008160938479663 3.7305825242718447 8.240291262135923 0.5020754788348019 0.3462849026834517 2.2148520410126937 1.861210565609195 1.3394131933179945 0.3209721672484884 0.0002977092470169 1.0 1.0 0.5970702236031354 0.0003278164997314 +Electron transport 13 48 2.5823400351158776 0.0098132843505369 14.983009708737864 45.592233009708735 1.1180311721330871 0.3315827540150002 5.69510117113123 4.184313965655804 1.5984402393879058 0.3574888993156041 5.386850318010218e-05 0.0010870000966304 3.9049312504264524e-06 3.597736784406734e-06 6.33317697687351e-05 +Sterol metabolism 10 26 2.503337985063761 0.0123027993588202 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 7.401993321500112e-05 1.0 0.371655018795122 0.0009951056419778 8.337420261083056e-05 +Antiport 7 9 2.4573180443612643 0.013997870057318 3.2063106796116503 7.097087378640777 0.8539962634551548 0.3166005193161004 2.0440914093762896 1.1428508308135348 1.2051823486844502 0.2998011899649158 0.0021155878345267 1.0 1.0 0.3879443652654283 0.000277756887713 +Hydrogen ion transport 8 22 2.4452397812944 0.0144755866306796 6.152912621359223 19.560679611650485 0.8019462838912398 0.3170771992837126 2.890966221074556 1.405159537040464 1.2709247974732976 0.29451915785821 7.840532600374473e-05 0.0092510900433489 0.0354914601129098 0.0063239101987386 8.665500923261924e-05 +Cholesterol metabolism 9 24 2.257935882424548 0.0239496571281532 7.111650485436893 23.79854368932039 1.169709264926864 0.2871268807807383 2.8890755390042298 2.7173834172675666 1.205315163774447 0.3061468445376054 0.0002355677663993 1.0 0.3530974878629287 0.0007016746800212 0.0002619380543045 +Steroid metabolism 10 27 2.2235237097618645 0.0261805064416158 7.703883495145631 26.439320388349515 1.128083592407629 0.3052190273048834 3.279782799169419 3.1412859163137186 1.216134343451914 0.3162944576553002 0.0002448403174687 1.0 0.4129317333780675 0.0020419820824666 0.0002745691183549 +Steroid biosynthesis 8 21 2.19223387582186 0.0283626235750384 6.351941747572815 21.094660194174757 1.1936032046421512 0.306057763510231 2.838692628881621 2.6297902443336034 1.071011617665077 0.2981933340003868 6.0690391746310944e-05 1.0 0.2518545844225215 0.0056128198685199 6.711779371444596e-05 +Symport 6 8 2.1403790030374217 0.0323241499915119 2.844660194174758 6.961165048543689 0.6469017708869542 0.3932450371351912 1.8940749800794765 1.272733699501336 1.0491712043829624 0.3136298512602674 0.4901762206910109 1.0 1.0 0.5661975770404395 0.4978168612908779 +Sterol biosynthesis 7 16 2.107245732247208 0.0350962846680447 4.970873786407767 15.854368932038836 1.2489526119817105 0.2730082640054638 2.2746228138386324 2.237837752303934 0.9571049414552286 0.2704007779320353 5.0814428209822654e-05 1.0 0.191600110602388 0.0017432511761074 5.564378317152988e-05 +Adaptive immunity 7 14 2.082691139376606 0.0372793856268929 4.143203883495145 13.968446601941748 0.5718686468442667 0.5057512333092327 1.8737785476971824 1.931213842986535 0.8618291696256006 0.3181645561745452 0.2807752737435819 1.0 1.0 0.7476848655039455 0.2894589157522063 +Sodium transport 5 7 2.055055797624916 0.0398736156567576 2.6432038834951457 6.033980582524272 0.3870777500167291 0.4312394754850888 1.6104565556558244 1.45275455788244 1.082646403381691 0.3149069735017896 0.4743980740883797 1.0 1.0 0.5553918894123164 0.4819543230991074 +Phospholipid metabolism 9 17 2.054198364964762 0.0399564966008869 5.706310679611651 15.194174757281552 0.9499140430417652 0.282763149469861 3.1039684871946744 2.8053632837701987 1.3505948321648105 0.2868829019946007 0.073146977469922 1.0 1.0 0.3157753203157507 0.0767262889545654 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3a3c82373ad3fe5d43d73e111610404cada5df83 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 169, + "title": "Average number of proteins per term", + "value": 34.082840236686394 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7cd63158a77adebd9779ff539b07613dd562bcea --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fe53089bd0e74314a3b52bdd3c438ff8aa33cd26 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,50 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.4757507846369071 5.026118185498186 5.005075037025381e-07 8.458221201679859e-05 8.458576812589795e-05 568 O43169,Q9UDW1,Q9BQE5,O60830,Q8N4H5,O43707,P24390,P36543,Q9NS69,O14949,Q8N1F7,Q99595,O75027,P00846,O14678,O43676,Q9C0H2,Q9Y6C9,Q96PU8,Q9BXS5,O95197,Q9H3N1,O75964,Q9Y584,O43808,Q9H2D1,O14925,Q9HD47,Q9P2W9,Q16134,Q96ES6,Q86Y82,Q53FT3,Q8NFH5,Q9H1E5,Q7L0J3,Q96CU9,P03886,P41208,O15498,P50416,Q9UBX3,O43731,P21796,P49257,Q9Y3A6,Q9H2V7,Q8WTW3,P45880,Q9BSK2,Q12846,O00461,O43752,Q5JRA6,O95070,Q70HW3,Q9P0J0,P08183,O15127,P33527,Q12768,P24539,Q8NFH4,P23786,P33897,P61026,Q12907,Q9H2J7,Q86Y39,Q9H4A6,Q969X5,Q8N4V1,P53985,Q15629,Q9NP58,Q9BRG1,Q8TAD4,P61019,O00400,P51572,O15439,P05023,P52292,Q9H2C2,Q6I9Y2,Q96B49,Q9HD42,Q13505,Q9H0U4,Q8TB61,P98164,P62820,P00403,Q9BUN8,O60499,Q9Y5J9,P82979,Q96A65,Q9H9B4,Q8N2H4,Q9C0E2,Q96QD8,Q9Y277,Q9HD20,Q9Y2T2,O75746,O95249,Q6DKK2,Q8N1S5,O43681,Q96RL7,Q8N5M9,P11717,Q14203,Q9Y6M9,Q969Q5,P61020,P51970,A0FGR8,O60220,P12235,Q9H173,Q9Y619,Q04656,Q9Y282,Q13586,O95563,Q99720,Q99584,Q969M3,Q15904,Q9Y3E7,Q92973,O14964,Q9BUR5,P51797,Q8NE01,O60427,Q15388,Q9H267,Q8N1B4,Q8TEM1,P61916,Q96RQ1,Q9NZJ7,Q9UJS0,Q9NUT2,Q9Y6M7,Q9Y255,Q15363,Q14849,O15504,O15397,Q9Y3E0,Q9UM00,Q9Y5J6,P55011,O95139,P51798,Q9UPT5,O95168,A6NIH7,Q8IXU6,P12236,Q03518,P12270,P05026,O15118,O43615,Q9H4M9,O95202,Q99442,Q9UID3,O96008,Q12981,P49321,Q9BQT8,O96000,Q6P4Q7,P30825,Q96L92,Q9NV96,O95159,Q96ED9,Q96AA3,O75381,Q8TD16,Q93050,O14653,Q8WVM8,Q9Y3C0,Q9BTX1,Q9Y3A3,O95721,P23634,Q96FV9,Q9BPX6,Q7Z3B4,P56385,Q15043,P46379,P20020,P21912,Q9Y5L4,Q06787,Q96RD7,P06576,P05141,O95373,P16615,Q9HC21,P49755,Q9NR31,Q9UP83,Q9Y487,Q9P0T7,Q13190,Q6NUK1,Q9NWR8,P51790,Q99758,Q96S66 222 +Protein transport 0.4096063685017269 3.891620930048359 9.957673640093034e-05 0.0166884846767179 0.0084142342258786 291 O60830,O43707,Q8N4H5,P24390,Q9NS69,Q8N1F7,Q99595,Q9BXS5,Q9Y584,O14925,Q9HD47,Q9P2W9,Q86Y82,Q53FT3,Q8NFH5,P41208,O15498,O43731,P49257,Q9Y3A6,Q8WTW3,Q5JRA6,O43752,O95070,O15127,Q12768,Q8NFH4,P61026,Q12907,Q9H4A6,Q15629,Q9BRG1,P61019,P51572,P52292,Q96B49,Q9HD42,Q9H0U4,Q13505,P62820,Q9BUN8,O60499,Q9Y5J9,Q96A65,Q8N2H4,Q9C0E2,Q9HD20,Q9Y2T2,O95249,Q96RL7,Q8N5M9,Q969Q5,P61020,O60220,Q9H173,Q99584,Q969M3,Q9Y3E7,Q92973,O14964,Q15388,Q9H267,Q8N1B4,Q8TEM1,Q15363,O15504,O15397,Q9Y5J6,Q9UPT5,A6NIH7,Q03518,O43615,Q9UID3,P49321,Q96L92,Q96ED9,O75381,Q8TD16,O14653,Q8WVM8,Q9Y3C0,Q9BTX1,O95721,Q7Z3B4,Q9Y5L4,O95373,P49755,Q9NR31,Q9UP83,Q9P0T7 90 +Sphingolipid metabolism 0.8180095411489348 3.1923566063379227 0.0014111699219885 0.2123143173929849 0.0596219292040154 12 Q06136,O95470,P17900,P04062,Q13510,Q16880,Q8N5B7,O15269,P07602 9 +Translocation 0.5541220693897794 3.098472706986586 0.0019452088625175 0.2804004823975137 0.0644785869468505 53 O75381,O60830,Q8TD16,Q8TEM1,Q9NS69,Q8N1F7,Q15629,Q9BTX1,Q99595,O15504,Q9Y5J6,Q7Z3B4,Q9Y584,Q9Y5J9,O14925,P12270,Q9Y5L4,O43615,Q8NFH5,P41208,Q9H173,O60220,Q8NFH4 23 +Respiratory chain 0.5562284613216124 3.0417422782672503 0.0023521318900907 0.3283235463023814 0.0644785869468505 34 O95139,Q9UDW1,Q96CU9,Q86Y39,Q6DKK2,P03886,O14949,P00403,Q9P0J0,O43676 10 +Ion transport 0.5460557541156343 2.9783734561954938 0.0028978266209294 0.3876453390566651 0.0644785869468505 66 Q9H2J7,Q93050,Q9Y6M7,P00846,Q8TAD4,P23634,Q9C0H2,Q9BPX6,P56385,O75964,Q15043,P20020,Q96RD7,O95202,P06576,Q9Y277,P16615,Q8N1S5,Q9Y487,P21796,P45880,Q6P4Q7,Q9NWR8,Q13586,P51790,Q15904,P51797,Q8NE01,Q96S66,P24539 30 +Lipid transport 0.5563226443682096 2.831695065227066 0.0046301981829106 0.5435703405651175 0.073164859549916 28 Q9H2C2,Q9BQE5,Q99720,Q9Y255,Q14849,Q9BUR5,O15118,Q9H2V7,Q9UID3 9 +ER-Golgi transport 0.5116530659246802 2.673966379825771 0.0074959965951491 0.7196160425111211 0.073164859549916 55 P24390,Q96RQ1,Q969X5,Q8WVM8,Q15363,P61019,P51572,O95197,Q9P2W9,O95249,P49755,Q12981,O15498,Q9NR31,O43731,P49257,Q9Y282,Q5JRA6,O95070,O95159 20 +Calcium transport 0.7491282093360925 2.6453378709758804 0.008160938479663 0.7496404483650225 0.073164859549916 11 P16615,Q13586,P20020,Q96RD7,P23634,O95202,Q9BPX6 7 +Electron transport 0.4976487644622246 2.5823400351158776 0.0098132843505369 0.8111186205663048 0.0783672010260081 48 O43169,O95139,Q9H1E5,Q9UDW1,Q96CU9,Q86Y39,Q6DKK2,P03886,O14949,P00403,Q9P0J0,Q16134,O43676 13 +Sterol metabolism 0.5235757222980917 2.503337985063761 0.0123027993588202 0.876568482923286 0.0866322121516928 26 Q9H2C2,Q16850,O75845,P04062,P04035,Q15125,Q14739,O15118,Q15800,Q15392 10 +Antiport 0.7477100709152056 2.4573180443612643 0.013997870057318 0.9076669517689898 0.0873705050208876 9 P12236,P51790,P51798,P51797,O95202,P05141,P12235 7 +Hydrogen ion transport 0.5554517756589179 2.4452397812943993 0.0144755866306796 0.9149276528064488 0.0873705050208876 22 P56385,Q93050,O75964,Q15904,P00846,Q9Y487,P06576,P24539 8 +Cholesterol metabolism 0.5091511032194156 2.257935882424548 0.0239496571281532 0.9833733443905384 0.1124303348516081 24 Q9H2C2,Q16850,P04062,P04035,Q15125,Q14739,O15118,Q15800,Q15392 9 +Steroid metabolism 0.4884941340040044 2.2235237097618645 0.0261805064416158 0.9887056721687432 0.1137234939090562 27 Q9H2C2,Q16850,O75845,P04062,P04035,Q15125,Q14739,O15118,Q15800,Q15392 10 +Steroid biosynthesis 0.5333172873140728 2.19223387582186 0.0283626235750384 0.9922694224751616 0.1151443766932503 21 Q16850,Q53GQ0,O75845,P04035,Q15125,Q14739,Q15800,Q15392 8 +Symport 0.6992533090742632 2.1403790030374217 0.0323241499915119 0.9961242697332732 0.1270414267108258 8 Q9H2J7,Q9H936,P53985,Q9Y6M7,Q96QD8,P55011 6 +Sterol biosynthesis 0.5651596932477136 2.107245732247208 0.0350962846680447 0.9976133299092256 0.1348016388386262 16 Q16850,O75845,P04035,Q15125,Q14739,Q15800,Q15392 7 +Adaptive immunity 0.5798355968385567 2.082691139376606 0.0372793856268929 0.998372406864734 0.1369612211074979 14 P01889,P10321,Q03518,P04439,Q9NZ08,P04083,Q07021 7 +Sodium transport 0.7214657506195159 2.055055797624916 0.0398736156567576 0.9989684261444886 0.1385627723900956 7 Q9H2J7,P55011,Q9Y6M7,Q96QD8,P05023 5 +Phospholipid metabolism 0.5476407199210134 2.054198364964762 0.0399564966008869 0.9989833667399692 0.1385627723900956 17 Q96N66,O14735,Q9NPH0,Q92604,Q9HCL2,Q8NF37,Q9UG56,Q9HBU6,Q9NUQ2 9 +Amino-acid transport 0.6605478678339385 1.9354917516739596 0.0529299798742544 0.999898006369184 0.1708309864299567 8 Q96NB2,Q9H2J7,Q6P4A7,P30825,Q9H9B4,P08195,Q96QD8 7 +Sensory transduction 0.7977685572639259 1.898648429705148 0.0576107162852572 0.9999558503484768 0.1708309864299567 5 P50897,Q9H6K4,O60313 3 +Vision 0.7977685572639259 1.898648429705148 0.0576107162852572 0.9999558503484768 0.1708309864299567 5 P50897,Q9H6K4,O60313 3 +GPI-anchor biosynthesis 0.6870488165943571 1.8820513019792589 0.059829050427524 0.9999703548337244 0.1708372841991875 7 O43292,Q9H490,Q5H8A4 3 +Cholesterol biosynthesis 0.5459813735100035 1.859420959300048 0.0629674932229011 0.9999831524369224 0.1744509238470541 14 Q16850,P04035,Q15125,Q14739,Q15800,Q15392 6 +Phospholipid biosynthesis 0.5225841708463104 1.812074021767181 0.0699747597889957 0.9999952618343428 0.1823262262162238 16 Q96N66,O14735,Q92604,Q9HCL2,Q8NF37,Q9UG56,Q9HBU6,Q9NUQ2 8 +ATP synthesis 0.6156619676150987 1.7479127332683555 0.0804791396166384 0.9999993051228034 0.2029996208240581 9 O75964,P00846,P56385 3 +Notch signaling pathway 0.6272362242572266 1.574713995516434 0.1153224758513933 0.9999999989845372 0.270687478040076 7 P05067,Q9UBV2 2 +Apoptosis 0.3783338160235891 1.4856611190026323 0.1373687798054983 0.999999999985729 0.2866089356435706 133 P52756,P09601,Q9NZJ7,Q96KA5,Q9UHX1,Q9UDX5,Q9Y255,P05067,Q96FV9,O95197,Q96A26,O95470,P12236,P46379,Q6NUQ4,Q9H3K2,Q9Y371,Q12981,O60313,O14681,P21796,Q07820,Q9NR28,O14737,Q9Y3D6,Q9H2J4,Q9P0J0,Q9UBK9 28 +Potassium transport 0.684537246049655 1.3911090272226885 0.164192367881867 0.9999999999999316 0.3303394068099469 5 P05023,Q9NUT2,P55011,P05026 4 +Zinc transport 0.8793006204173657 1.3690354181049131 0.1709882039324877 0.9999999999999828 0.3360117030766328 3 Q8TAD4,Q8N1S5 2 +Neurotransmitter transport 0.8276931754089211 1.1672028188175951 0.2431284728296172 1.0 0.441814106539842 3 Q7L0J3,Q9H2J7 2 +Exocytosis 0.4142505411966541 1.032292195593513 0.3019352560280768 1.0 0.5002652771445586 16 Q5JRA6,Q9UPT5,Q9BRK5,P11233,Q96A65 5 +Ubiquinone biosynthesis 0.5612710700827385 0.831750390912047 0.405549851003482 1.0 0.6119457573177541 5 Q5HYK3,O75208,Q8NI60 3 +Biomineralization 0.7225042301184347 0.7662022963768529 0.4435559422157884 1.0 0.6352623240209173 3 P22413,Q6P4Q7 2 +Chemotaxis 0.5692524682651539 0.6951352107088354 0.4869705703906897 1.0 0.6801489784795584 4 O94813,P26583,P09429 3 +Cell adhesion 0.3093286103167869 0.6707757113887095 0.5023634226626785 1.0 0.6846727292741345 36 Q14254,Q08722,P06756,P15151,Q08380,Q9P273,P35580,Q03001,Q9BX67,O60245,P05026,P05067,Q92859,P10586,O60716,Q08431 16 +Sodium/potassium transport 0.6841511562323658 0.6282673768641401 0.5298287989078498 1.0 0.7106433890113224 3 P05026,P05023 2 +Peroxisome biogenesis 0.6779469825155005 0.6066199622224738 0.5441031493945856 1.0 0.7183861894350388 3 P56589,P40855 2 +Aromatic hydrocarbons catabolism 0.6684522131378667 0.5637955279762974 0.5728932956373018 1.0 0.7390760836847635 2 P07099 1 +Detoxification 0.6684522131378667 0.5637955279762974 0.5728932956373018 1.0 0.7390760836847635 2 P07099 1 +Phagocytosis 0.5197032599095017 0.5012795845841347 0.6161743711315393 1.0 0.7706009227468072 4 P50570 1 +Cilium biogenesis/degradation 0.3015055782659182 0.4987272643847853 0.617971534578476 1.0 0.7706009227468072 27 Q15154,Q9Y366,A6NIH7,O95684,O95721,Q9H4M9,Q96J42,Q15051 8 +Unfolded protein response 0.3868202770288678 0.4654824965190668 0.6415859686888161 1.0 0.7911172756382623 10 Q13217,Q9GZP9,Q9BUN8,Q15629 4 +Angiogenesis 0.3274401018667742 0.4257317392636502 0.6703033316995535 1.0 0.7977553736424263 16 Q9H2J4 1 +Stress response 0.2640477289243529 0.2072661509313761 0.8358020077749437 1.0 0.9112938020255836 33 P51812,O95197,Q14011,Q86TM6,Q15418 5 +Lipid metabolism 0.2833845257363093 0.1840647358635437 0.8539626704802936 1.0 0.9192337026189148 139 P23786,P54619,Q96G23,Q06136,Q8N2A8,Q9H7Z7,Q16880,Q8N5B7,Q9HBU6,Q15392,P37268,Q9H2C2,Q9P035,P51648,Q9NPH0,P17900,O95470,P04062,Q8NF37,Q13510,Q16739,O15118,P07602,Q9UKU0,P27544,Q16836,O75845,Q92604,Q9HCL2,P04035,Q15125,P50416,Q9UG56,Q9H6V9,Q9NP80,Q15800,Q96N66,Q16850,O14735,Q8NCC3,Q53GQ0,Q15067,O15269,Q8NHP8,Q9BY49,Q14739,Q8NCG7,Q9NUQ2,A1L0T0 49 +Autophagy 0.2424083564707952 0.0635913179494985 0.9492956450237338 1.0 0.9761145432635854 38 Q9Y371,P53365,Q9H0U4,P13473,P62820,O14681,Q969Q5,O95721,Q9NQ88 9 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cda3db92f9c3fec0550b2c4f857d48247dbf2507 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEX1", "API5", "APOBEC3C", "APOL2", "APOO", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMC10", "ARMT1", "ARV1", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATF7IP", "ATG13", "ATG2B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATRX", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCLAF1", "BCOR", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP3", "CASP7", "CASP8", "CBL", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CEP250", "CEP290", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "COASY", "COG1", "COG3", "COG5", "COG7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COPZ1", "COQ5", "COQ8A", "COQ9", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CWC15", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCTD", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDHD2", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPY30", "DPYSL2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FNBP1", "FOXC1", "FOXRED1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGT7", "GHITM", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HERC2", "HERC5", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOOK3", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IRAK1", "IRF2BP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KCTD21", "KCTD5", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDLR", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC41", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MANF", "MAP1S", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MESD", "METTL1", "METTL3", "MFGE8", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICALL1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMGT1", "MMS19", "MOB4", "MOCOS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPP5", "MRE11", "MRGBP", "MRI1", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NEO1", "NES", "NFRKB", "NFS1", "NGEF", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME3", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRDE2", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGFR", "OGT", "OPA1", "OPA3", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OTUD6B", "OTULIN", "OXSM", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PANK3", "PANK4", "PANX1", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD8", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMS1", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIP5K2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKAG1", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK2", "PTK7", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PURB", "PUS1", "PUS7", "PVR", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RICTOR", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN3", "RMND1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORT1", "SPAG5", "SPATA5", "SPC24", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPIN1", "SPNS1", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STK26", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNGR2", "SYS1", "SYVN1", "TACC3", "TADA3", "TAF6", "TAF6L", "TAF7", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TBPL1", "TCAF1", "TCEA1", "TCERG1", "TDRKH", "TECR", "TEFM", "TENM3", "TERF2IP", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TK1", "TLE3", "TLK2", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM14C", "TMEM214", "TMEM30A", "TMEM9", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TSC2", "TSFM", "TSG101", "TSNAX", "TSR1", "TSR2", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TTPAL", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGT8", "UHRF1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VTA1", "WAPL", "WARS", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WDR12", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR48", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WLS", "WTAP", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "ZBTB10", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFPL1", "ZMYM2", "ZMYND8", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZZ3"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ACOX1", "ACP6", "ACSL6", "ACTN4", "AGPAT5", "ALDH3A2", "ANXA1", "AP1M1", "AP3M1", "APOL2", "APOO", "APP", "ARFIP2", "ARV1", "ASAH1", "ASNA1", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7A", "BAG6", "BCAP31", "BICD2", "BNIP1", "C1QBP", "CD47", "CDIPT", "CERS1", "CERS2", "CERS5", "CETN2", "CHMP1A", "CHMP3", "CIRBP", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLPTM1L", "CNNM3", "CNNM4", "COG1", "COG5", "COQ5", "COQ8A", "COQ9", "COX2", "CPT1A", "CPT2", "CTNND1", "CYB5B", "CYP51A1", "DAGLB", "DCTN1", "DERL1", "DERL2", "DHCR24", "DIABLO", "DNAJC3", "DNM2", "DST", "EBP", "EHD1", "EI24", "ENPP1", "EPHX1", "ERAP1", "ERGIC1", "ERGIC2", "ERGIC3", "ESYT2", "ETFDH", "ETNK1", "EXOC4", "EXOC7", "FADS1", "FAM162A", "FDFT1", "FGFR1OP", "FIS1", "FLOT2", "FMR1", "FOXRED1", "GBA", "GHITM", "GM2A", "GOLIM4", "GOLPH3", "GOLT1B", "GOSR1", "GOSR2", "GPAA1", "GPAM", "HACD3", "HADH", "HGS", "HIKESHI", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMGCR", "HMOX1", "HOOK2", "HSD17B12", "IFT52", "IGF2R", "ILVBL", "IPO7", "IPO8", "IQCB1", "ITGAV", "JAGN1", "JAM3", "KDELR1", "KDELR3", "KDSR", "KPNA2", "LAMP2", "LBR", "LDAH", "LETM1", "LGALS3BP", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP2", "MBOAT7", "MCL1", "MCUB", "MFGE8", "MFSD3", "MIA3", "MICU1", "MMGT1", "MOB4", "MPC2", "MSMO1", "MTCH1", "MTCH2", "MTFP1", "MTX1", "MYH10", "NASP", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NEO1", "NPC1", "NPC2", "NUP210", "NUP35", "NUP37", "NUP54", "NUP93", "NUPL2", "OPA1", "OPA3", "PANX1", "PCDH7", "PCM1", "PDCD5", "PDCL3", "PECR", "PEX14", "PEX19", "PEX3", "PIGG", "PIGU", "PISD", "PLA2G15", "PLBD2", "PLD6", "PNPLA8", "PPT1", "PRELID1", "PRKAG1", "PSAP", "PTGES2", "PTPRF", "PUF60", "PVR", "QKI", "RAB10", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB5B", "RALA", "RANGRF", "RBM5", "RFT1", "RPS6KA1", "RPS6KA3", "RTN3", "S100A13", "SAR1A", "SARNP", "SC5D", "SCAMP2", "SCFD1", "SDF4", "SDHB", "SEC62", "SEL1L", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIL1", "SLC12A2", "SLC16A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SNAP29", "SNX27", "SPNS1", "SPTLC1", "STARD3", "STIM1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "SV2A", "SYS1", "SYVN1", "TAP1", "TENM3", "THOC1", "THOC7", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8A", "TIMM8B", "TMCO1", "TMED10", "TMED2", "TMED5", "TMEM214", "TMEM30A", "TMEM9", "TMX1", "TMX4", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TPR", "TRAM1", "TTC19", "TTYH3", "TXNDC15", "UGCG", "UGT8", "UNC119B", "UQCR10", "UQCRQ", "UXT", "VDAC1", "VDAC2", "VDAC3", "VPS13A", "VPS25", "VPS33B", "VPS51", "VPS52", "WASHC3", "WASHC5", "XPO4", "YIF1A", "YIPF5", "YKT6", "ZFPL1"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9c23ec9ae9b901b545c1614859800bb3504a003c --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Congenital disorder of glycosylation", "1": "Cataract"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/plot_0.png b/protein_atlas_disease_involvement/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0f9f6f632ec3b5de7bae9531e3bd131e1a02fb32 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb97beb953b580d8398097e915bc2ff4a66b2278a09f5d909f27af8bed6edc1b +size 202127 diff --git a/protein_atlas_disease_involvement/advanced/plot_1.png b/protein_atlas_disease_involvement/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..285405599091a9fe45934bde78aa3c6c60767922 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4e5a89c639f5ebf3aea89e1d75e49a2dee3de2df6a52a009b9b453063de5189 +size 198351 diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e02c4ae523fbadf3221a154806387fc3b84cf59 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Congenital disorder of glycosylation", "1": "Cataract", "2": "Primary mitochondrial disease", "3": "Cardiomyopathy", "4": "Ciliopathy", "5": "Hereditary spastic paraplegia", "6": "Parkinsonism", "7": "Proto-oncogene", "8": "Deafness", "9": "Neurodegeneration"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/plot_0.png b/protein_atlas_disease_involvement/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7665527e26967b806d87ac39770ad06bf011e800 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a74497829a963850ff18553b13b1b8691264238d65603f978c70363f110d51fc +size 149357 diff --git a/protein_atlas_disease_involvement/basic/plot_1.png b/protein_atlas_disease_involvement/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0cf5e616b4b0742a0a8389b16eceebcc4eee932c --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da62f301fdd3801e4048b20ccc7e0e3768ef44e252128b7c8eeea5356fe45f7c +size 138360 diff --git a/protein_atlas_disease_involvement/basic/plot_2.png b/protein_atlas_disease_involvement/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..3ffc2218b2f8f5e810d0f4cd4b5872236700796b --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6338427bd3557d38e0146023058c3cd85c244197316e3dc188987beca495481b +size 147284 diff --git a/protein_atlas_disease_involvement/basic/plot_3.png b/protein_atlas_disease_involvement/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..c9b90909de7591784d5c108a595027faa4bbc69a --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2cbad74a31f303f5093d090f741b133904f4ed839309063c51ed07f806a41f0 +size 147248 diff --git a/protein_atlas_disease_involvement/basic/plot_4.png b/protein_atlas_disease_involvement/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..06f165a54a136f23e2dc6a9eb4075fa84040197c --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9627677e45037c9162a0c445e80b3d14633a808a5130ed06171821a1ef45259 +size 143540 diff --git a/protein_atlas_disease_involvement/basic/plot_5.png b/protein_atlas_disease_involvement/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..50322bf55961beb993adec70bbf5535b4bd13baf --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d156f4c217aaaa3a9a5a7d1eacdc2074575ca1052aab38c34cf24a9df8b47491 +size 152755 diff --git a/protein_atlas_disease_involvement/basic/plot_6.png b/protein_atlas_disease_involvement/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..25481f81d9af05f613b334900208e357e00897cf --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb5bf41109488c6f0c11b3275112246decfa5796cb0cc2b56285529ac8986166 +size 136235 diff --git a/protein_atlas_disease_involvement/basic/plot_7.png b/protein_atlas_disease_involvement/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..fd6d6c620b98788e173cd3ae319147056f29ea08 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e6998db5f87d82d0cb5498cf6d97615a4a27beac2056bf1834e33b314ce8614 +size 148463 diff --git a/protein_atlas_disease_involvement/basic/plot_8.png b/protein_atlas_disease_involvement/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e2b48cf3da1a570cc4e733a7f85203cf0d8d5c0c --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0140ff9f2b8844f195685be4a2e7fc0477f5bb2185e5f79dc2ec96ab0857c237 +size 145827 diff --git a/protein_atlas_disease_involvement/basic/plot_9.png b/protein_atlas_disease_involvement/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..4d572bb80b51215dcc092e38efc8599ee0436596 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58db96bfdde475e33b0492849cc7bd0b94493605272a177c4f0f4d437944e267 +size 146123 diff --git a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b05e0283292107cc5e3566f9bb55770253ccf762 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:403c519716910c7c9438a028c91f32a2009e88fde8624b3b3876dd62e6dbf25f +size 84994 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..944b70bd94add07c06d74ab1eb97e0233e57d740 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Congenital disorder of glycosylation 10 21 2.6326744919000147 0.0084715494580036 5.618932038834951 18.325242718446603 0.4013656328493284 0.4500757016048167 2.8520016519219875 3.440343696044481 1.1296344785223882 0.3186521023843959 0.0052037962080083 0.018891152845815 0.0693457394610891 0.0949405615621671 0.0056200963406339 +Ichthyosis 3 10 2.373265007123216 0.0176316084915371 2.424757281553398 8.70873786407767 0.6701903086786922 0.3798909770564678 1.5631275250389387 1.4270688811262522 1.102920967881483 0.3152318826682235 0.0337948818896463 0.1155957163384056 0.2223047329091382 0.1300982938321277 0.0353483729682259 +Cataract 6 28 2.232910456991649 0.0255548498638813 7.509708737864078 26.679611650485437 0.6066406061606927 0.4718259290301406 3.570701015264242 3.2395121058789256 1.0572468917106954 0.3422408621391183 0.018556415929551 1.0 0.4242240140575919 0.048897845662748 0.0199020946739293 +Gangliosidosis 3 5 2.1543664844292034 0.0312114427761556 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 2.515035347033685e-05 0.0233225886554715 0.0008973897437505 0.0001354907423541 2.661109756617399e-05 +Mucopolysaccharidosis 3 5 2.099537749496873 0.0357695237455721 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 0.0013168186836578 1.0 1.0 0.027832231049335 0.00138858926748 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f0936323a1dba8a9d82d59d74386964d5e94a507 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 119, + "title": "Average number of proteins per term", + "value": 23.899159663865547 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..73ee00923c6b14ff2715e41eece07c1eefdd1489 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b1c7f2bcfc9f88e72feaca778fe3512d094fca6b --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,51 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Congenital disorder of glycosylation 0.5917896641076215 2.6326744919000147 0.0084715494580036 0.6366572959198187 0.2622701763116145 21 Q8N511,P15291,P51571,O75787,Q9BT22,Q15904,P46977,Q9UP83,Q9HC07,Q96AA3 10 +Ichthyosis 0.7273845061906143 2.3732650071232153 0.0176316084915371 0.8795931348294869 0.2622701763116145 10 Q15125,P04062,P51648 3 +Cataract 0.4869069127116704 2.232910456991649 0.0255548498638813 0.9540664073532016 0.3095134741968765 28 Q9H6K4,Q15125,O76024,O00400,Q15800,P08670 6 +Gangliosidosis 0.8566485725402582 2.1543664844292034 0.0312114427761556 0.977025235798602 0.3095134741968765 5 P07602,P16278,P17900 3 +Mucopolysaccharidosis 0.8438984518335373 2.099537749496873 0.0357695237455721 0.98689244678739 0.323886019545421 5 P54802,P15586,P16278 3 +Ehlers-Danlos syndrome 0.8941627480761498 2.0737316768684466 0.0381042375935789 0.990177243797294 0.323886019545421 4 Q8NCH0 1 +Primary mitochondrial disease 0.4310112828330432 1.832797141648342 0.0668327444030387 0.9997338175288236 0.4324306971474941 106 Q9Y2R0,Q86Y39,O14949,Q7LG56,P00846,O43676,Q5XKP0,Q53H12,Q9Y584,P00403,Q9NPL8,Q96CU9,O75208,Q6DKK2,P03886,Q96I36,O60313,P13073,Q9UBX3,Q9BUB7,Q9BQT8,P12235,Q70HW3,Q9P0J0,Q7KZN9 25 +Leber hereditary optic neuropathy 0.9791372991260204 1.818134640134539 0.069043556687415 0.9997992784089608 0.4324306971474941 2 P00846 1 +Gaucher disease 0.9520721736678848 1.7059680605295566 0.0880140264348603 0.9999826782842468 0.479936671786059 2 P07602 1 +Dystonia 0.6396748465303176 1.639263833194924 0.1011583247853418 0.999996921771483 0.5027884828814851 7 P51572,O60220,Q15043 3 +Neuronal ceroid lipofuscinosis 0.9481105470953156 1.6380909660402934 0.101402719236602 0.9999970197897416 0.5027884828814851 3 P50897,O14773 2 +Emery-Dreifuss muscular dystrophy 0.6851755028702536 1.607216528031138 0.1080068775846583 0.9999987611486654 0.5141127373029736 6 Q8WXH0,P02545,P50402 3 +Lissencephaly 0.576122507496605 1.538506255940752 0.123924880093543 0.99999985464825 0.5502838858684771 10 O43505,Q6ZXV5,Q9H9S5,Q9Y320 4 +Amyloidosis 0.6865253910869467 1.4001526874571206 0.1614676003423247 0.9999999992077506 0.6862373014548803 5 P03886,Q9Y287 2 +Limb-girdle muscular dystrophy 0.5543459172580226 1.3534713161407794 0.1759051076100992 0.9999999998997028 0.7218175105379935 8 O14979,Q9H9S5,Q5JTV8,P02545 4 +Cardiomyopathy 0.3842671311319557 1.268416993137692 0.2046490763093733 0.9999999999985328 0.7610387525254821 27 O43819,P50402,Q53H12,Q9BTV4,P02545,O60313,Q969Y2,P00846,Q9NX14,P09493,Q9H9S5,P12235 12 +Peroxisome biogenesis disorder 0.6917271571425778 1.2137551826065076 0.2248412251289118 0.9999999999999312 0.7768510071515982 4 P40855 1 +Zellweger syndrome 0.6917271571425778 1.2137551826065076 0.2248412251289118 0.9999999999999312 0.7768510071515982 4 P40855 1 +Meckel syndrome 0.685658219638063 1.1875423807364018 0.2350137500626683 0.9999999999999856 0.7768510071515982 4 Q15058,Q96J42 2 +Congenital muscular dystrophy 0.6199293137793807 1.0964943833436047 0.2728624799725891 1.0 0.7998638796368237 5 O43505,Q9H9S5 2 +Progressive external ophthalmoplegia 0.5784555893512394 1.0902946900613768 0.2755833534883174 1.0 0.7998638796368237 6 Q7LG56,P12235 2 +Dystroglycanopathy 0.6464029728868129 1.01855974106537 0.3084120253115463 1.0 0.808970477587315 4 O43505 1 +Niemann-Pick disease 0.7815054976036016 0.9983525826055324 0.3181084181283586 1.0 0.808970477587315 2 O15118 1 +Osteopetrosis 0.7750211446292523 0.9720806434150976 0.3310104309804398 1.0 0.8156830361954555 2 Q86WC4 1 +Osteogenesis imperfecta 0.4649329811794841 0.8909130321346612 0.3729758282890059 1.0 0.8156830361954555 9 Q32P28,Q96AY3 2 +Leigh syndrome 0.4471521417934987 0.8878196519158241 0.3746377701821539 1.0 0.8156830361954555 11 P00846 1 +Ciliopathy 0.3954130092064122 0.8593861908752631 0.3901274857926209 1.0 0.8156830361954555 15 Q9Y366,Q2M1P5,Q15058,Q9UBB4,Q96J42,Q15051 6 +Hirschsprung disease 0.7448548068790314 0.8514469750451871 0.3945211066598519 1.0 0.8156830361954555 2 P42892 1 +Craniosynostosis 0.6048543974374341 0.8421981294807718 0.3996770606498041 1.0 0.8156830361954555 4 P16435 1 +Alzheimer disease 0.5166883290078212 0.7928137064536809 0.4278863696058077 1.0 0.828802620351456 6 P03886 1 +Hereditary spastic paraplegia 0.3858449382579973 0.7925718519113853 0.428027313825335 1.0 0.828802620351456 15 P49902,Q9BRK0,O94905,O00400,Q12768,Q8N0X7 6 +Allergen 0.7237101776148752 0.7688365875682134 0.4419903257882378 1.0 0.828802620351456 2 Q9BPX6 1 +Obesity 0.4690363426464453 0.7448870248136564 0.4563400196563305 1.0 0.8304859944430422 7 Q9C0B1,Q2M1P5,P22413 3 +Parkinsonism 0.3926290262031564 0.726253707784459 0.467683252520048 1.0 0.8306612992520257 13 Q96A57,P04062,Q15043,O75569,O75787 5 +Spinocerebellar ataxia 0.4322823852030907 0.7079162591132482 0.4789972621559091 1.0 0.834426858040209 9 O15020,O14773,Q8IV08 3 +Intrahepatic cholestasis 0.7042571186918569 0.6946390465126423 0.4872815357415512 1.0 0.834426858040209 2 Q9UJS0 1 +Diabetes mellitus 0.3691466085364223 0.5778015327823535 0.5633981203225482 1.0 0.85512228045899 13 P03886,P22413,Q13217,O76024 4 +Rhizomelic chondrodysplasia punctata 0.6424139875916537 0.4871056796811375 0.6261834416449104 1.0 0.9087296287285894 3 O15228,P50542 2 +Proto-oncogene 0.2949727559517563 0.4098628774707303 0.6819065384304115 1.0 0.937496317293962 50 Q15154,Q8WY22,Q06136,Q9BZ95,P35637,Q01105,Q15022,Q03164,Q92804,O96028,Q92733,Q01844 12 +Leukodystrophy 0.3141693788343763 0.4034588333451521 0.6866107132827255 1.0 0.937496317293962 20 P07602 1 +Deafness 0.299063587432835 0.3522848152351909 0.7246246748481695 1.0 0.968880183223957 60 Q9NR28,Q16740,O60313,Q9Y287,Q9NWM8,P33527,O00400,O60220 8 +Non-syndromic deafness 0.2892406798336198 0.2814758127920018 0.7783454770619427 1.0 1.0 22 P33527,Q9NR28 2 +Amyotrophic lateral sclerosis 0.3009135129294322 0.2376085865705638 0.812184690110044 1.0 1.0 14 Q99720 1 +Neurodegeneration 0.2713284084692415 0.2059512362685462 0.8368290024752723 1.0 1.0 152 Q96D71,P61026,Q8TD16,P35637,O14653,P02545,O75787,P50897,P05067,O00400,P05023,P07196,Q8TB36,Q9HD42,O15020,P04062,P54802,Q13510,Q9BRK0,Q9UBB4,Q15043,P06865,O14773,O75503,Q8IV08,P27544,P49902,P03886,Q96A57,Q96RL7,Q9NW15,O60313,Q96RR1,Q14203,Q8N0X7,Q03252,Q10713,Q99720,Q9Y320,Q14108,O15269,Q13217,Q12768,Q9Y287 44 +Parkinson disease 0.3166396539356839 0.1506539967918664 0.8802486641702434 1.0 1.0 9 P04062 1 +Nephronophthisis 0.3706817857694749 0.0739351943645087 0.9410619514205494 1.0 1.0 4 Q15051 1 +Bardet-Biedl syndrome 0.4647490129723736 0.068766914139125 0.945175154412502 1.0 1.0 3 Q2M1P5,O15078 2 +Autism 0.3196952595936847 0.0206951479308271 0.983488839582678 1.0 1.0 5 Q9HCK8,P27635,O14874,P51608 4 +Xeroderma pigmentosum 0.4137055837563516 0.0171675649973735 0.9863029377570895 1.0 1.0 3 P19447,P18074 2 +Cockayne syndrome 0.4137055837563516 0.0171675649973735 0.9863029377570895 1.0 1.0 3 P19447,P18074 2 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ab9e0b51b9ee268b327ce5e8058abcc8c0b06200 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD1", "ABCD4", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP1S1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARPC1B", "ARV1", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG13", "ATIC", "ATM", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATRX", "ATXN10", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "CAD", "CALR", "CAMK2G", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT5", "CDC16", "CDC20", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CDX2", "CENPE", "CENPF", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHMP1A", "CHMP2B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "COA3", "COA7", "COASY", "COG1", "COG5", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCAF8", "DCTN1", "DDHD2", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPAGT1", "DPH1", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "ECT2", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHMT1", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOC6B", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "FADS1", "FADS2", "FAF1", "FAH", "FAM120A", "FAM126A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GRB2", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GTF2H1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIP1", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT52", "IGBP1", "IGF2R", "IGHMBP2", "IKBKB", "ILF3", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "IPO7", "IQCB1", "IRF2BPL", "IRS4", "ISCA2", "ITGAV", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KCTD21", "KDM1A", "KDM3B", "KDM5C", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KMT2A", "KNL1", "KTN1", "L2HGDH", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIN9", "LIPA", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRP2", "LRPPRC", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARS", "MARS2", "MASTL", "MATR3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED13", "MED17", "MED23", "MED25", "MESD", "MFGE8", "MFN2", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOCOS", "MOGS", "MORC2", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NARS2", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCOR1", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NEO1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OMA1", "OPA1", "OPA3", "OSBPL2", "OSGEP", "OSTM1", "OTUD6B", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PANX1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDHA1", "PDHB", "PDK1", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPIP5K2", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R5D", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PSPH", "PTDSS1", "PTK2", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAD21", "RAD23B", "RAD54B", "RALGAPA1", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RBPJ", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFK", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "ROCK1", "ROCK2", "RP2", "RPA2", "RPIA", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RRM2B", "RSBN1L", "SACS", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SBF1", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC33A1", "SLC38A2", "SLC39A14", "SLC3A2", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRP54", "SRP72", "SRSF2", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STIM1", "STMN1", "STRAP", "STRN", "STT3A", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE1", "SYNE2", "TAF15", "TAF6", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCOF1", "TECR", "TELO2", "TENM3", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM22", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TK1", "TKFC", "TKT", "TLK2", "TMCO1", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM25", "TRIM27", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TSR2", "TTC19", "TTC21B", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP4", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBE3A", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WASHC4", "WASHC5", "WBP2", "WDR1", "WDR26", "WDR36", "WDR4", "WDR45B", "WDR5", "WDR73", "WFS1", "WIPI2", "WNK1", "XIAP", "XPNPEP3", "XPO1", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["ABCC1", "AGK", "ALDH3A2", "ALG1", "ANO10", "APP", "ASAH1", "ATP1A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATXN10", "B4GALT1", "B4GAT1", "BCAP31", "BCKDK", "BICD2", "BRI3BP", "C19orf70", "CEP290", "CERS1", "CHD8", "CHMP1A", "CHST14", "CLN5", "CLPP", "COA3", "COG5", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "DCTN1", "DIABLO", "DNAJC3", "EBP", "ECE1", "EMD", "ENPP1", "ERCC2", "ERCC3", "ERLIN2", "EWSR1", "FKBP10", "FKBP14", "FKRP", "FOXRED1", "FTO", "FUS", "GBA", "GDAP1", "GLB1", "GM2A", "GNPAT", "GNS", "GOSR2", "GTPBP3", "HEXA", "HNRNPDL", "IFT52", "IQCB1", "ITM2B", "KDSR", "KIF14", "KIF7", "KMT2A", "LMNA", "LMNB2", "MECP2", "MICU1", "MSMO1", "NAGLU", "ND1", "NDUFA11", "NDUFA13", "NDUFB11", "NDUFB3", "NEFL", "NPC1", "NSD2", "NSD3", "NT5C2", "OPA1", "OPA3", "OSTM1", "P3H1", "PCM1", "PEX19", "PEX5", "PLD3", "PMPCA", "POR", "PPT1", "PRCC", "PRKRA", "PSAP", "RAB10", "REEP2", "REPS1", "RFT1", "RPL10", "RRM2B", "SCARB2", "SCO2", "SET", "SIGMAR1", "SLC25A10", "SLC25A13", "SLC25A21", "SLC25A26", "SLC25A4", "SLC33A1", "SLC39A14", "SPART", "SPTBN2", "SPTLC1", "SSR4", "STT3A", "SUZ12", "SYNE2", "TAF15", "TIMM22", "TIMM8A", "TIMMDC1", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMTC3", "TMX2", "TOR1AIP1", "TPM1", "TPP1", "TTC19", "TWNK", "TXNDC15", "UQCRQ", "VIM", "VPS13A", "WASHC5", "WFS1"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json b/protein_atlas_molecular_function/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..daa9bd8e6cb328a671ea6b8245d6817c3fe2d9fa --- /dev/null +++ b/protein_atlas_molecular_function/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Glycosidase", "2": "Translocase", "3": "Host cell receptor for virus entry"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/plot_0.png b/protein_atlas_molecular_function/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f40080e1471dc8bb459b89a999b10507851d3099 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c276642ce81ee3dd59f0acf4f8e704d2e91cb5a55300d7bceba2cb945ee2ee2c +size 199680 diff --git a/protein_atlas_molecular_function/advanced/plot_1.png b/protein_atlas_molecular_function/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..bfbe590953aaafe033e82adf2921956df4e062be --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4374b0e8fc4a0d690f23402567f060c2f91428413311cc6fb93642d634f483e3 +size 189009 diff --git a/protein_atlas_molecular_function/advanced/plot_2.png b/protein_atlas_molecular_function/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ecc7a79161dee7ebba66847ed298fda85ca0e7dd --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fbc4e6f89c7f7fbb093467140a6621deab6a7dbab6434ec8994189e0e3107e6 +size 190713 diff --git a/protein_atlas_molecular_function/advanced/plot_3.png b/protein_atlas_molecular_function/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..8962693cca7dd38de69aadda0771fba839b347a0 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95d5c6845799f19e9efbf15b7fdf93809faff0462938c417a9f81ecfa94f7708 +size 193052 diff --git a/protein_atlas_molecular_function/basic/idx2term.json b/protein_atlas_molecular_function/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..96781945d52a7837fe032d5f4a083664af48170b --- /dev/null +++ b/protein_atlas_molecular_function/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Glycosidase", "2": "Translocase", "3": "Host cell receptor for virus entry", "4": "Rotamase", "5": "Glycosyltransferase", "6": "Acyltransferase", "7": "Metalloprotease"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/basic/plot_0.png b/protein_atlas_molecular_function/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c3c05da4c34e126187fe83e46b1868c1c89f74c1 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fcb0b0820749ad3208952d387b38dcf458a78c6d094b4b2f4dd44201ebcbfd83 +size 137340 diff --git a/protein_atlas_molecular_function/basic/plot_1.png b/protein_atlas_molecular_function/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..57fbbcb9aae099515fe2c142d2ec766d1c305f61 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3b6dc7633d4b9e5f9f0211c4fc57769c97d5a59146be4e261851c8a4c207878 +size 138214 diff --git a/protein_atlas_molecular_function/basic/plot_2.png b/protein_atlas_molecular_function/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..2bd2bdfe4a01b7de83f14d348ac67aa24b782013 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:77506067d7f2796ed703dcdef25937ea085827a9f89cde31fb2b447638103676 +size 130609 diff --git a/protein_atlas_molecular_function/basic/plot_3.png b/protein_atlas_molecular_function/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..c9cf1bef3ece652027a34474f9e233da2c821948 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d191f835c3f743ec6df718e6ea17fa61b43f470b55ac6adc25631018360a0e2 +size 140506 diff --git a/protein_atlas_molecular_function/basic/plot_4.png b/protein_atlas_molecular_function/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..5f7947a9c9dc5f6eed5346ccf6fb955e7d05388c --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e1459d095172feee629a66fe81cef18f496bdc1549a0a2609611c6992b06c1d7 +size 129250 diff --git a/protein_atlas_molecular_function/basic/plot_5.png b/protein_atlas_molecular_function/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..f4e3b8be72c6a99484b27622e08125948a87b4b2 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f184d7ad041dc144c7de91ee7248c90ca611733dc32be33d24e830305260e68c +size 146050 diff --git a/protein_atlas_molecular_function/basic/plot_6.png b/protein_atlas_molecular_function/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..5a6b6545d94b18ed19ff9e518a84ad4a996069e3 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ab9208ed5c9bd363ebfbe4a1302066655381bf4f19ae3101fe73735c1f3b7d9 +size 146911 diff --git a/protein_atlas_molecular_function/basic/plot_7.png b/protein_atlas_molecular_function/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..1124600de529cb6594752e50c7edc9e4516bd00e --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e911ef46eac2f8390a535301645de23d1a1267af1097442809b6505f4a692035 +size 146058 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b4670ad6687df1d395dadfd0d223c4dc854394da --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b79fe59dcb5636a12d90727166b2e0492c09541362b82c6e50a18e12ff9d33d +size 91137 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..acd7795a70bea8e24c04db3e878d8502b736a830 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 25 43 4.295783547204285 1.7407737443964066e-05 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0927441716558062 0.1129146346736405 0.0927526620327515 0.018618787305556 0.1020993084411343 +Glycosidase 11 20 3.0706111217220715 0.0021362117892105 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 2.692657300537401e-05 1.0 0.3404254693467198 0.0005468287448316 3.042567652627972e-05 +Translocase 16 30 2.7426780011200163 0.006094041097838 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.0001116526614054 1.0 0.1132051672598368 0.0031898046957766 0.0001266725713312 +Host cell receptor for virus entry 6 16 2.2494233437776665 0.0244855748013248 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.0491243876092767 1.0 1.0 0.0808776862517318 0.0516637732040453 +Carboxypeptidase 4 6 2.1193699296342823 0.0340592160240902 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0324301480805536 1.0 0.0088504827764808 0.0498779046475234 0.0336357980244025 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4d6d842ce9b0b95da1168ae0069e19fd2f5a5625 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 42.78350515463917 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8a91f4ef47be3b36d7b572b17648b19372347048 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fbc1a03a7f0d4d4f46b44745d878c8984c1d02fc --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,20 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.683802555587946 4.295783547204285 1.7407737443964066e-05 0.0016871404049731 0.0010320400534853 43 P06756,P24390,Q5KU26,Q9NS69,O00264,O75787,P10586,P98164,Q07954,P55899,Q8WTV0,O15118,Q15375,P02786,O15173,O15031,Q99623,P11279,O43731,P30825,Q99720,Q9Y5M8,Q14739,Q14108,P35613 25 +Glycosidase 0.6657247384190261 3.0706111217220715 0.0021362117892105 0.1873332736733758 0.029601791936203 20 P08236,Q8IW92,P10253,O00754,P04062,P54802,Q9BTY2,O60476,P06865,P06280,P16278 11 +Translocase 0.5386579870692764 2.7426780011200163 0.006094041097838 0.4472947926359388 0.0435222607829238 30 P33527,Q9HD20,P33897,P16615,P03886,P00403,Q13423,P20020,Q9NP58,Q03518,Q99758,P08183,P23634,P06576,O15439,P05023 16 +Host cell receptor for virus entry 0.5861154192358315 2.2494233437776665 0.0244855748013248 0.9097040038529294 0.1260299393546742 16 P06756,Q8WTV0,Q14108,P11279,O15118,P35613 6 +Carboxypeptidase 0.7945576781379919 2.1193699296342823 0.0340592160240902 0.9653104381115072 0.1436410414929023 6 Q9HB40,P42785,O75976,P10619 4 +Rotamase 0.4612055284374802 1.942617587422464 0.0520623803096174 0.9944071056216356 0.1758669317262386 25 Q9Y680,P26885,Q96AY3,Q9NWM8,O95302,P62942 6 +Porin 0.8614935573254678 1.9383644582925104 0.0525787734026899 0.994695044593275 0.1758669317262386 4 P45880,P21796 2 +Glycosyltransferase 0.3849885786471634 1.5278763020363626 0.1265432530437396 0.9999980028247571 0.3409637651456316 38 Q10472,P04062,Q13126,Q16739,Q16880,P43490,Q9BT22,P46977,O43505,Q8N4A0 10 +Muscle protein 0.5594373195214634 1.2186489784429584 0.2229774508345996 0.9999999999764462 0.5407203182739041 7 Q05682,P09493,P46020,P67936 4 +Serine protease 0.511309715512783 1.16420333984822 0.2443416170809327 0.999999999998424 0.5481101280985777 10 Q16740,O14773,Q9H300 3 +Monooxygenase 0.8151740648278267 1.1184834910083243 0.2633605535204424 0.999999999999867 0.555347254162672 3 Q6UW02 1 +Acyltransferase 0.3194791040379092 0.791850934971279 0.4284475988549432 1.0 0.6455477072568946 40 P23786,Q96N66,Q8NCC3,Q92604,Q8NF37,Q9HCL2,O15269,Q9UJ14,P50416,Q9NXS2 10 +Metalloprotease 0.3305535779384972 0.7808469857980497 0.4348924955151321 1.0 0.6455477072568946 29 Q9UIQ6,Q7Z2K6,O75844,Q92905,Q9BYT8,Q5JRX3,Q9NZ08,Q96TA2,P42892,Q96E52,O75976 11 +Guanine-nucleotide releasing factor 0.3510890188879449 0.7639323405543713 0.444907563640736 1.0 0.6455477072568946 22 P80303,Q9HD47,Q02818 3 +Calcium channel 0.716018048505359 0.7424322645674611 0.4578254771459793 1.0 0.6455477072568946 3 Q9UM00,Q96RD7 2 +Heparin-binding 0.4681120633062871 0.740158147909762 0.4592040391827394 1.0 0.6455477072568946 7 P05067,P10586 2 +Serine protease inhibitor 0.4676985415516472 0.3193965622961331 0.749425817315331 1.0 0.8386402255378228 4 P05067 1 +Protein phosphatase inhibitor 0.5539892867211813 0.2218797866149609 0.8244074662955991 1.0 0.9087218662576492 2 Q12972 1 +Prenyltransferase 0.3754583921015492 0.0825698229004272 0.9341935971496044 1.0 0.9743739669194796 4 P49356,P53611,P49354 3 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4f7924d56a858dfd29ec99b2086bfd578fd7b5fa --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCA3", "ABCB1", "ABCB6", "ABCC1", "ABCC4", "ABCD1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFAP1", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "AMPD2", "ANKHD1", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATF7IP", "ATG3", "ATG4B", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATRX", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD2", "BRD4", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CAD", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBL", "CBR1", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CEP290", "CERS1", "CERS2", "CERS5", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ5", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCTD", "DCTPP1", "DCXR", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EFNB1", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "F11R", "FADS1", "FADS2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FOXRED2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDGF", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED1", "MAGED2", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MATR3", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL9", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCOS", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTF2", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NARS2", "NAT10", "NAXE", "NCBP2", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFRKB", "NFS1", "NGEF", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OTUD6B", "OTULIN", "OXNAD1", "OXSM", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDP1", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PIGA", "PIGG", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PVR", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD54B", "RAD54L2", "RALA", "RALGAPA1", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO4", "RFC1", "RFC3", "RFK", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP8", "RRP9", "RSBN1L", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBF1", "SC5D", "SCAF1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP1", "SENP3", "SENP6", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIN3B", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMCHD1", "SMG1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPIN1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "SSU72", "STAMBP", "STAMBPL1", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STMN1", "STRBP", "STRN", "STRN3", "STT3A", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "SYVN1", "TAF15", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBPL1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "TGS1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TMCO1", "TMEM109", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP12", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TST", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "ULK3", "UMPS", "UNC45A", "UPF1", "UPF2", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VPS72", "VRK1", "WARS", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR48", "WDR5", "WLS", "WNK1", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "ZADH2", "ZBTB10", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFR", "ZMPSTE24", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2", "ZZZ3"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCC1", "ABCC4", "ABCD1", "ALG1", "APP", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP6AP2", "B4GAT1", "BSG", "CALD1", "CLPP", "COLEC12", "COPS5", "COX2", "CPD", "CPT1A", "CPT2", "CTSA", "CYP20A1", "ECE1", "EPHA7", "ERAP1", "ERMP1", "FCGRT", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP7", "FKBP9", "FNTA", "FNTB", "FUCA2", "GAA", "GALNT1", "GALNT4", "GBA", "GGT7", "GLA", "GLB1", "GLB1L2", "GPAM", "GUSB", "HEXA", "ITGAV", "KDELR1", "KDELR3", "LAMP1", "LBR", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "MAN1A2", "MAN2B1", "MBOAT7", "MTAP", "NAGLU", "NAMPT", "ND1", "NLN", "NNT", "NPC1", "NUCB1", "NUCB2", "OMA1", "PANX1", "PARL", "PGRMC1", "PGRMC2", "PHB2", "PHKA1", "PITRM1", "PLA2G15", "PLXNB2", "PPP1R8", "PRCP", "PTPRF", "QPCTL", "RABGGTB", "RANGRF", "SCARB1", "SCARB2", "SCPEP1", "SIGMAR1", "SLC7A1", "SPTLC1", "SRPRB", "STT3A", "TAP1", "TFRC", "TMCO1", "TOMM22", "TPM1", "TPM4", "TPP1", "UGCG", "UGT8", "VDAC1", "VDAC2", "YME1L1", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fba674c3e906e0f212b39ce4511a9f5e51b32e9e --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "CD markers", "3": "Predicted secreted proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..dccbf44d440ff6ff4e981c74a6436239941de6a2 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0fbabaf22e7456527a79f7b677b5d4f12f5187c78f76539ee938490db514017 +size 216694 diff --git a/protein_atlas_protein_class/advanced/plot_1.png b/protein_atlas_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2ca4ee5c8882c2424a108c3d5cd389dbe3c2ba23 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99fe1df53f98c0f8650c6eef83406c4591544e7d73ac972a6347d65bda3153d7 +size 208681 diff --git a/protein_atlas_protein_class/advanced/plot_2.png b/protein_atlas_protein_class/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0c4aecb08b04e0a654c81c947e55316545b01f7b --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:655a5e0c26e0785b0546ca101bcdf6b55f5e3b41e1fa30da138529c124b9f867 +size 180658 diff --git a/protein_atlas_protein_class/advanced/plot_3.png b/protein_atlas_protein_class/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..79584b3848c90232928010e2176d5c8bcd68fb77 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c317420f60a438b5736b7ddea1ed597ce4040132ac57b46bd55d979d0eee2517 +size 198861 diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..92aa3a48429079b6a1a1d940881fa364ac623267 --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "CD markers", "3": "Predicted secreted proteins", "4": "Disease related genes", "5": "Human disease related genes"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..71ed1d945819775c6e9b4726980e28de219c3330 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:49e76883e0f5072b5ea296dc795fa9d6de46c00046a46492f89bece2dc04ad43 +size 141054 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6e6c9a0c558bbff6267248e47105236dd8e7ef84 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f60f0d858032c0c8c9282ab6243335058061231717467fdcbb02f08fd3600809 +size 135301 diff --git a/protein_atlas_protein_class/basic/plot_2.png b/protein_atlas_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..79f8e32b34a459027682864112f94685a027c74e --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9959321993b34cdf601a949654ded646579520e9670daa4b2162b3f193557769 +size 134802 diff --git a/protein_atlas_protein_class/basic/plot_3.png b/protein_atlas_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..95879ec76e63eadb7ea1a9e66788b0196ca3c38a --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b393c2f048b29f4e5928b4fa0f71553a221334486c763a77434eb8a88d584736 +size 136665 diff --git a/protein_atlas_protein_class/basic/plot_4.png b/protein_atlas_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..4f8ef2b9b0b25d45aec72fac171b391ce521a9a0 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d14af55a912ce531a457db5a83198c57c734d94c67286d20dca7b03e7ab7670a +size 139134 diff --git a/protein_atlas_protein_class/basic/plot_5.png b/protein_atlas_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..02798ef0c6ede89b602e417c785419c77749c49c --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3956a96b3998911072e3d57e8f586f17906f93af703097295a00ecc78c7da7d +size 142448 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fe3b6d66852a6075014a3c5b35c0f34f884af872 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90ff1472d51683a64fe60a7b1affd75903b25c5dca2389cdd57205310cd05af8 +size 115514 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fbaa21ce80457799a33e7dc872f9495817357980 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 395 669 9.33481664167269 1.0116620287712631e-20 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 2.085372117626017e-67 2.9350632351920674e-11 7.291894317496681e-19 2.8564759771791496e-48 4.456235713895105e-67 +Transporters 214 415 6.582826179301435 4.6158868089461455e-11 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 2.7606852389033237e-35 0.1457253545247156 0.0012697106204538 2.569806647138743e-17 7.929390646129729e-36 +CD markers 9 18 2.511538607979166 0.0120206136339917 6.548543689320389 16.62378640776699 0.159361413045758 0.3347758559744795 3.625700175504636 4.1209525283344535 1.5119526885132668 0.3016304730463651 0.7614099525584477 1.0 1.0 0.7364809176311808 0.7711573125810836 +Predicted secreted proteins 27 59 2.0230636815065943 0.0430665823772784 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.0342537774116906 0.7237340949521109 0.735405710566665 0.4781264107059845 0.038848181715856 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..103e3b81c6cd035a03f47b97fc2f0754cae8398f --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 566.2 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..647334b009b96bcb6318c1e82a5329b1051a0b34 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c2aa7c4019996be678a0ba6246d1bb4e9cf14677 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.6737907755255695 9.33481664167269 1.0116620287712631e-20 2.0202332405754257e-17 1.0101166202877129e-17 669 O43169,Q8WY22,Q9Y2R0,Q9UDW1,Q9BQE5,O60830,P43307,P24390,P09601,Q9NS69,P67812,Q9UDX5,Q99595,P00846,O43676,P30519,Q9C0H2,Q4ZIN3,Q9HC07,Q6UW02,Q70UQ0,Q8N511,O43657,O95197,Q9NZ45,P51648,Q96A26,Q9NX00,O75964,Q9Y584,P55899,O14925,O60725,Q9P2W9,Q16134,Q6ZXV5,Q86UE4,Q96ES6,Q86YN1,P62942,Q9H1E5,O15173,Q96CP7,P57105,Q5VW38,Q9H4I3,P03886,Q3SXM5,O60637,Q13423,Q8IXM6,Q07065,P13073,Q9UBX3,O43731,Q15800,Q9H061,Q9H2V7,O75844,O43493,Q9NR28,Q9BSK2,O00461,O43752,Q8N0U8,Q9Y5M8,O95070,Q70HW3,Q9P0J0,Q8WVI0,Q14108,Q7KZN9,Q9UBV2,O15127,P33527,O75071,Q9H6K4,P35613,A1L0T0,O95772,P24539,Q9H330,Q96PC5,P33897,Q96G23,Q9H2J7,Q86Y39,O00264,Q8N4V1,Q96KA5,Q15629,O96005,Q15070,Q16880,Q8IZA0,Q8N8L6,Q9NQC3,Q8TAD4,Q9HBU6,O00400,Q15392,Q96E52,Q9H2C2,Q96EX1,Q5T9L3,Q13505,O95470,Q6NUK4,Q8TB61,Q96A33,P00403,Q9BUN8,O60499,Q9NR77,Q9UJ14,Q8WTV0,P27105,Q8N2H4,Q9NQX7,Q9UKU0,Q8IV08,P51812,Q9HD20,Q9NX40,Q9NX62,O95249,Q8N1S5,Q8NCH0,Q9HCL2,Q8N5M9,O60476,O14681,Q567V2,Q8TCT8,Q96J42,Q07820,Q8WVC6,P42892,P12235,Q08722,Q9Y619,Q16850,Q9GZP9,Q8NCC3,Q9Y282,Q13586,Q10472,Q99720,Q9NPA0,Q9HD45,Q15904,Q8TCD1,Q96KC8,Q14739,Q9BUR5,P51797,Q8NE01,Q9Y287,Q15388,Q06136,Q5KU26,Q96RQ1,Q9NZJ7,Q9Y6M7,Q9NZC3,Q15363,Q14849,O76024,P05067,Q8N8Q8,Q86WC4,P38435,O95139,O15260,Q9BRK0,Q8NF37,P12236,Q14534,O43292,Q03518,Q7Z3D4,Q86TM6,Q9NPL8,O15118,O94919,O95202,Q9UIQ6,Q9H3K2,P27544,O15031,P50402,P51571,Q96A57,Q9NW15,Q12981,Q15125,Q9BT22,P11279,Q9BUB7,Q9H300,Q9H6V9,Q7RTS9,P56378,Q8IYS2,Q92542,Q96N66,Q99805,P16435,Q16625,Q6P4Q7,Q9Y3D6,Q8TAA9,Q8N2F6,P30825,Q5H8A4,Q96JJ7,Q9BSR8,Q9NV96,Q8NCG7,O95159,Q9H6H4,O15269,Q8NAN2,Q96AA3,Q9NPR9,O75381,Q93050,Q9UH99,O14653,P13473,Q7LG56,Q9BTX1,P04439,Q8N5B7,P23634,Q92859,Q96FV9,Q9H9S5,Q9P035,Q92896,O14548,Q92804,Q8TBA6,Q16739,Q15043,P20020,P10321,Q6NUQ4,Q96RD7,P05141,P16615,O75845,Q9HC21,Q96I36,P49755,O43760,P04035,Q8IWA4,Q9Y487,Q9NP80,Q9UI14,Q9P0T7,Q9NWS8,Q7Z2K6,Q13190,Q53GQ0,Q6UW68,Q9NWR8,P27824,P51790,Q99758,Q9Y320,Q06481,P09493,Q9UBU6,Q96S66,P06756,O75880,P60228,Q8NHH9,Q8N2A8,Q8N1F7,Q6PI78,O75787,O75027,O15258,O14678,P46977,Q5JTV8,Q96TA2,Q9Y6C9,Q9H490,O75976,P37268,Q5SNT2,Q9P2K2,Q9H3N1,Q8NBX0,Q15005,O43808,P22413,O15400,Q86Y82,Q7L0J3,P15291,Q92604,Q8NBN3,P50416,Q14012,Q9UG56,O75448,P49257,Q9Y3A6,Q9NVH1,O14735,Q12846,Q5JRA6,Q86XL3,Q92544,P01889,Q00765,Q9P0S9,P08183,Q9NUQ2,Q8WXH0,Q99640,Q12907,Q96IX5,Q9Y6N1,Q96M27,Q969X5,P53985,Q9NP58,Q9NZ01,Q9Y262,Q96CS3,Q9Y2W6,Q16706,P51572,P10586,O15439,P05023,Q8TB36,Q92643,Q5BJF2,P15954,P98164,Q07954,Q9H9B4,Q96QD8,Q5VV42,Q15375,P02786,Q9NTJ5,Q9BTV4,P11717,Q96HV5,Q969V3,P26572,O95674,A0FGR8,Q86UP2,Q04656,O95563,Q969M3,P04844,Q6NTF9,O94901,O60427,Q8TCT9,Q99735,Q8TEM1,Q8IY95,Q9NUT2,Q14789,P04843,Q9Y3E0,Q9UM00,P55011,P51798,O43819,O95168,Q8IXU6,Q9P0I2,Q6ZRP7,P57088,P05026,Q96AG4,Q99442,Q86V85,O95864,Q05086,Q9Y276,Q9GZY8,Q96K12 395 +Transporters 0.565809211495657 6.582826179301435 4.6158868089461455e-11 9.231773813844073e-10 3.0772579392974307e-10 415 Q8WY22,P06756,P36543,P49458,P24390,Q8NHH9,Q8N1F7,O75787,O75027,O15258,O14678,P46977,Q9C0H2,Q9Y6C9,Q9HC07,Q8N511,Q9BXS5,P46934,Q9H3N1,O43808,Q9H2D1,Q15006,Q6ZXV5,Q07021,P07602,P62942,Q8NFH5,P57105,Q5VW38,O60637,P50416,Q07065,P13073,Q9UBX3,P49257,Q9H061,Q9H2V7,Q9Y512,O75844,P45880,Q9BSK2,Q12846,Q5JRA6,O43752,Q13438,Q92544,Q9BRK5,Q70HW3,Q14108,P08183,Q9UBV2,O15127,P33527,P35613,Q8NFH4,Q96PC5,P33897,Q9H2J7,Q8N4V1,P53985,Q15629,O96005,Q15070,Q9NP58,Q8TAD4,O00400,P51572,O15439,Q96E52,P05023,P52292,Q9H2C2,Q5T9L3,Q5BJF2,Q8TB61,Q96A33,P15954,P98164,P00403,Q9BUN8,Q07954,Q9NR77,Q96A65,Q8WTV0,P27105,Q9H9B4,Q9C0E2,Q9NQZ5,Q96QD8,O75955,P02786,O95295,Q9HD20,O75746,Q8N1S5,O43681,Q96RL7,O60313,P11717,Q96HV5,O14681,Q8TCT8,Q969V3,A0FGR8,P12235,Q08722,Q9Y619,Q9GZP9,Q04656,P20674,Q13586,O95563,Q99720,Q9NPA0,P04844,Q15904,Q92973,P40855,Q9BUR5,Q6NTF9,Q8NE01,O94901,Q9Y287,Q16891,Q8TEM1,P61916,P50570,Q8IY95,Q9NZJ7,Q9UJS0,Q9NUT2,Q9Y6M7,P04843,Q15363,Q14849,P04083,O15397,O76024,P05067,O15504,Q8N8Q8,Q9UM00,Q86WC4,P55011,P51798,O15260,Q9UPT5,Q8IYU8,Q8IXU6,P12236,Q9P0I2,Q03518,P57088,P12270,Q86TM6,P05026,O94905,Q96AG4,O15118,O95202,Q96A57,Q9NW15,P11279,Q9BUB7,Q9H300,Q9BQT8,Q96N66,Q99805,Q16625,Q6P4Q7,Q8TAA9,P30825,Q96JJ7,Q96L92,Q9NV96,Q96AA3,Q9UHB9,O75381,Q93050,Q9UH99,P13473,Q9Y3C0,Q9BTX1,P04439,P23634,Q9BPX6,Q7Z3B4,Q8TBA6,Q16739,Q15043,P20020,P21912,Q96RD7,P05141,O95373,Q9Y371,P16615,Q9HC21,P49755,P04035,Q8IWA4,Q9UI14,Q9P0T7,Q16543,Q13190,Q6NUK1,Q6UW68,Q9NWR8,O00429,O00560,Q99758,Q9Y320,Q9UBU6,Q96S66 214 +CD markers 0.6055614101596021 2.511538607979166 0.0120206136339917 0.214840901964862 0.0267124747422039 18 Q08722,P02786,P06756,P13473,Q07954,P11279,P08183,P22413,P35613 9 +Predicted secreted proteins 0.450873307248996 2.0230636815065943 0.0430665823772784 0.5853951082093017 0.071777637295464 59 Q08380,P80303,Q9NZ08,Q02818,P05067,Q9H9S5,Q08431,Q9Y4P3,Q9P2K2,Q8IW92,Q9HB40,P43490,P22413,Q9H6E4,Q6UX07,Q07021,O94919,Q15165,Q8WUJ1,Q9UM22,Q8NBM8,O00584,Q99584,Q9BTY2,Q8N128,Q9BUR5,Q9Y287 27 +Disease related genes 0.2238306587616048 1.0883596720547768 0.2764363570593597 0.9984528417661732 0.3949090815133711 1136 Q96D71,Q15154,Q9Y2R0,O75880,O43707,P36543,P09601,Q03164,O14949,Q9UHX1,Q8N1F7,Q6PI78,O75787,P50897,O75027,P00846,O14678,Q9BS16,O43676,P46977,Q5JTV8,Q96TA2,P00374,Q9H490,Q9HC07,P37268,Q8N511,Q9Y4P3,P51648,P17900,O15020,Q9Y584,Q9P0J1,Q13510,Q9H2D1,Q13126,P22413,P21953,Q16134,Q6ZXV5,Q07021,Q86YV9,O14773,P07602,Q53FT3,P22830,Q96CU9,P15291,P49902,P10253,Q15022,O14979,P03886,Q7L592,Q13423,P23246,P50416,P13073,P38159,P49257,Q15800,Q9H061,Q8N0X7,P10619,O75844,Q8WTW3,Q9NR28,O14874,Q86XL3,Q9BSJ2,Q15067,Q70HW3,P20700,Q9P0J0,P01889,O15460,Q14108,Q7KZN9,P08183,P33527,Q9H6K4,Q12768,Q8NFH4,Q8WXH0,P23786,Q96PC5,P33897,Q96IX5,Q86Y39,Q969X5,P53985,P28070,P02545,Q9NP58,Q9NZ01,O00400,Q5XKP0,Q15392,P51572,P16278,P10586,Q9H2C2,P05023,Q8TB36,Q9HD42,Q01105,O95470,Q8WVM7,Q92643,Q96A33,P04062,P54802,P00403,P98164,Q15058,Q07954,Q9UBB4,P07099,O75503,Q5VV42,Q9UKU0,Q8IV08,P51812,Q15051,P53350,P02786,Q9NX62,O75746,Q16822,P21964,Q6DKK2,Q96PU5,Q8NCH0,Q96RL7,Q96D53,O60313,Q8N5M9,O14681,O43505,Q96J42,Q9NWM8,P42892,P08670,O60220,P12235,Q9Y619,Q96HY6,Q13586,O00584,Q99720,Q15904,Q14739,P40855,P15586,Q9Y287,Q06136,P35637,Q16740,Q32P28,O76024,P05067,P06280,Q9NVI7,Q86WC4,P38435,P07196,Q9BZ95,Q9BRK0,O43292,Q03518,P06865,Q86TM6,Q9NPL8,O95684,Q92733,O15118,Q9UID3,P27544,P51114,P30153,O75208,P50402,P51571,P55795,Q9NW15,Q15125,Q9BT22,P98175,Q9BUB7,Q9BQT8,Q7RTS9,Q92542,Q96N66,P16435,Q16625,Q6P4Q7,Q8TAA9,Q5H8A4,Q96AY3,O15269,O96028,P46020,Q96AA3,O75381,Q8TD16,O14653,P13473,Q7LG56,P04439,O95721,Q9BPX6,Q9H9S5,Q9UGJ1,P07237,Q53H12,Q92804,Q8TBA6,Q15043,P10321,P21912,Q06787,Q96RD7,Q01844,Q16836,P16615,O75845,O00754,Q9HC21,Q96I36,Q15643,Q9UP83,Q9Y487,Q9NP80,Q9NWS8,P42345,Q6NUK1,P08236,Q03252,Q10713,Q969G3,O00429,Q99758,Q9Y320,Q9NRA0,P09493,Q13217,Q96S66 247 +Human disease related genes 0.227466923928014 0.7858153291182084 0.4319756846575147 0.999987772475606 0.5407859215544475 1030 Q96D71,Q9BQE5,O75880,O43707,P36543,P09601,Q03164,O14949,Q9UHX1,Q8N1F7,O75787,P50897,O75027,P00846,O14678,P46977,O43676,Q5JTV8,Q96TA2,P00374,Q9H490,Q9HC07,Q8N511,Q9Y4P3,P51648,P17900,O15020,Q9Y584,Q9P0J1,Q13510,P22413,P21953,Q16134,Q6ZXV5,Q07021,Q86YV9,O14773,P07602,Q53FT3,P22830,Q96CU9,P15291,P49902,P10253,O14979,P03886,Q13423,P50416,Q9UBX3,P38159,P49257,Q15800,Q9H061,Q8N0X7,P10619,O75844,Q8WTW3,Q9NR28,O14874,Q86XL3,Q15067,Q70HW3,P20700,Q9P0J0,P01889,O15460,Q14108,Q7KZN9,P08183,P33527,Q9H6K4,Q12768,Q8NFH4,Q8WXH0,P23786,P33897,Q96IX5,Q86Y39,Q969X5,Q04837,P53985,P02545,Q9NP58,Q9NZ01,Q9HBU6,O00400,Q5XKP0,Q15392,P51572,P16278,P05023,Q9H2C2,Q8TB36,Q9HD42,Q01105,O95470,Q8WVM7,Q92643,P98164,P04062,P54802,P00403,Q15058,Q9UBB4,Q9NR77,Q9NQZ5,O75503,Q8IV08,P51812,Q9NX62,O75746,P21964,Q6DKK2,Q96PU5,Q8NCH0,Q96RL7,Q96D53,O60313,O43505,Q9NWM8,P42892,P08670,O60220,P12235,Q9Y619,Q96HY6,Q13586,O00584,Q99720,Q14739,P40855,P15586,Q9Y287,Q06136,P35637,Q16740,Q32P28,O76024,P05067,P06280,Q9NVI7,Q86WC4,P38435,P07196,Q9UPT5,Q9BRK0,O43292,Q03518,P06865,Q9NPL8,O15118,O95202,P27544,P30153,O75208,P50402,P51571,P55795,Q9NW15,Q15125,Q9BT22,P98175,Q9BUB7,Q9BQT8,Q7RTS9,O96000,Q92542,Q96N66,P16435,Q16625,Q6P4Q7,Q8TAA9,Q5H8A4,Q5HYK3,Q96AY3,O15269,O96028,P46020,Q96AA3,O75381,Q8TD16,O14653,P13473,Q7LG56,Q9H7Z7,P04439,O95721,Q9BPX6,Q9H9S5,Q9UGJ1,P07237,Q53H12,Q15043,P10321,P21912,Q06787,Q96RD7,Q16836,P16615,O75845,O00754,Q9HC21,Q96I36,Q15643,Q9UP83,Q9Y487,Q9NP80,Q9NWS8,P42345,Q6NUK1,P08236,Q03252,Q10713,Q969G3,O00429,Q99758,Q9Y320,P09493,Q13217 219 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0bb3b52d269892a0b3e41600e8461e64da676660 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKS1A", "ANLN", "ANO10", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASB6", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG2B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf198", "C1orf35", "C2CD2", "C2CD5", "C5orf22", "C5orf51", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CENPH", "CENPI", "CENPK", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG1", "COG3", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FADS1", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM160B2", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FOXRED2", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD3", "KCTD5", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF11", "KIF13B", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLHDC4", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL9", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OTUD4", "OTUD6B", "OTULIN", "OXA1L", "OXNAD1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGA", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RICTOR", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "SYVN1", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCD", "TBCE", "TBCEL", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM41A", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTPAL", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UHRF1BP1", "ULBP3", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS52", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR73", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFPL1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF106", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ACOX1", "ACSL6", "ACTN4", "AGK", "AGPAT5", "ALDH3A2", "ALG1", "ANKLE2", "ANO10", "ANXA1", "AP1M1", "APLP2", "APOL2", "APOO", "APP", "ARL10", "ARMC10", "ARV1", "ASAH1", "ASNA1", "ATAD3A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5F1", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7A", "ATXN10", "B4GALT1", "B4GAT1", "BCAP31", "BCKDHB", "BCKDK", "BCS1L", "BICD2", "BNIP1", "BRI3BP", "BSG", "C14orf2", "C18orf32", "C19orf70", "C1QBP", "CAMK1", "CANX", "CCDC134", "CCDC47", "CD47", "CDC37", "CDIPT", "CDKAL1", "CDS2", "CENPK", "CERS1", "CERS2", "CERS5", "CHMP1A", "CHST14", "CISD1", "CKAP4", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLN5", "CLPP", "CLPTM1", "CLPTM1L", "CNNM3", "CNNM4", "COA3", "COG1", "COG5", "COLEC12", "COMT", "COQ5", "COQ8B", "COQ9", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2L", "COX7C", "CPD", "CPT1A", "CPT2", "CTSA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DAGLB", "DCAKD", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHFR", "DHRS13", "DIABLO", "DNAJC1", "DNAJC11", "DNAJC3", "DNM1L", "DNM2", "DOLPP1", "DYM", "EBP", "ECE1", "EFCAB14", "EI24", "EIF3E", "EIF3L", "EMC2", "EMC3", "EMC7", "EMD", "ENDOD1", "ENPP1", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN2", "ERMP1", "ESYT2", "ETFDH", "ETNK1", "EWSR1", "EXOC4", "EXOC7", "FADS1", "FADS2", "FAF2", "FAM162A", "FAM177A1", "FAM8A1", "FAR2", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FIS1", "FKBP10", "FKBP14", "FKBP1A", "FKRP", "FLOT1", "FMR1", "FOXRED1", "FUCA2", "FUS", "FXR1", "GAA", "GALNT1", "GBA", "GDAP1", "GDE1", "GGCX", "GGT7", "GHITM", "GLA", "GLB1", "GLB1L2", "GLG1", "GM2A", "GNS", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPR107", "GPR108", "GPR180", "GUSB", "HACD3", "HADH", "HEXA", "HIKESHI", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMGCR", "HMOX1", "HMOX2", "HNRNPDL", "HNRNPH2", "HPS6", "HSD17B12", "HSDL1", "ICMT", "IGF2R", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "IPO7", "IPO8", "IQCB1", "ITGAV", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KIAA0319L", "KIAA2013", "KIF14", "KMT2A", "KPNA2", "KTN1", "LAMP1", "LAMP2", "LBR", "LDAH", "LETM1", "LGALS3BP", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRRC59", "LYSMD3", "MAN1A2", "MAN2A1", "MAN2B1", "MBOAT7", "MCL1", "MCUB", "MED24", "MFF", "MFGE8", "MFN1", "MFSD3", "MGAT1", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIGA1", "MMGT1", "MPC2", "MPV17L2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "NAGLU", "NAMPT", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB6", "NEDD4", "NEDD4L", "NEFL", "NEO1", "NNT", "NPC1", "NPC2", "NRM", "NSD2", "NSD3", "NT5C2", "NUCB1", "NUCB2", "NUP210", "NUP35", "NUP37", "NUP54", "NUP93", "NUPL2", "OCIAD1", "OCLN", "OMA1", "OPA1", "OPA3", "OS9", "OSTM1", "OXA1L", "P3H1", "P4HA2", "P4HB", "PANX1", "PARL", "PCK2", "PCM1", "PCYOX1L", "PDP1", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PHKA1", "PIGG", "PIGK", "PIGU", "PISD", "PKMYT1", "PLA2G15", "PLD3", "PLD6", "PLK1", "PLXNB2", "PMPCA", "PNPLA8", "PON2", "POR", "PPP2R1A", "PPT1", "PRCC", "PRRC1", "PSAP", "PSMB4", "PTGES2", "PTPRF", "PUF60", "PXMP2", "QSOX2", "RABAC1", "RBM10", "RBMX", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RFT1", "RHBDD2", "RMND1", "RNASET2", "RPN1", "RPN2", "RPS6KA3", "RRM2B", "RTN3", "RTN4", "S100A13", "SACM1L", "SAMM50", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC62", "SEL1L", "SET", "SFPQ", "SFXN1", "SGPL1", "SH3GLB1", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC4A7", "SLC6A15", "SLC7A1", "SMARCE1", "SMIM12", "SMIM4", "SNAP29", "SNAPIN", "SNX27", "SPART", "SPCS2", "SPHK2", "SPNS1", "SPPL2A", "SPTBN2", "SPTLC1", "SQLE", "SRP68", "SRP9", "SRPRB", "SSBP1", "SSR1", "SSR4", "STAG1", "STARD3", "STARD3NL", "STARD7", "STIM1", "STOM", "STT3A", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUN1", "SUN2", "SURF4", "SUZ12", "SV2A", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "SYVN1", "TAF15", "TAP1", "TBL2", "TDRKH", "TECR", "TFRC", "TGOLN2", "THOC1", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM8A", "TIMMDC1", "TLCD1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM41A", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TOMM20", "TOMM22", "TOR1AIP1", "TPM1", "TPP1", "TPR", "TRABD", "TRAM1", "TRIP11", "TSPAN3", "TSPAN6", "TTC19", "TTYH3", "TUBGCP2", "TUBGCP4", "TXNDC15", "TXNDC16", "UBE3A", "UGCG", "UGT8", "UQCR10", "UQCRQ", "USMG5", "VANGL1", "VDAC2", "VIM", "VKORC1L1", "VPS13A", "VPS51", "WASHC3", "WASHC5", "WFS1", "WLS", "XPO4", "YIF1A", "YIPF4", "YIPF5", "YME1L1", "ZFPL1", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..514a9c6345619a6d7fbb06b4aae091c5480963eb --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Golgi apparatus", "1": "Endoplasmic reticulum", "2": "Mitochondria", "3": "Vesicles", "4": "Nuclear membrane"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/plot_0.png b/protein_atlas_subcellular_location_all/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ca45f0f2e0c1336a0d9f6d370bc6199bbe613b58 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a79ce7d9343d938eda0ac6521894524bd11047b39889cefa250ac2cd63cb427 +size 208000 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_1.png b/protein_atlas_subcellular_location_all/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..655c61119c6d477cb567eb2fbccb59bd5976617f --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:413e840501f30448d2ce6baae3a87d708451ef3e9f2e7027e55db43d2d607202 +size 205395 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_2.png b/protein_atlas_subcellular_location_all/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6bcf23e965d1baa2750a71d2e5de163d23db3c03 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:23db855cbe8e84f65abcd8fd31e1ee5d9e7c53987d87540ffa2f68547befcf50 +size 211684 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_3.png b/protein_atlas_subcellular_location_all/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..a8da487e174b12096c64b14c530bfb0d585f1b88 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e933284c913b6651c43012405069f610703080285c8d6239a0a447c30dcf7166 +size 207029 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_4.png b/protein_atlas_subcellular_location_all/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..1e00ba84c3745e6ded0f9759d356f51167fd8072 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8956f779942653a01cad664cb419218dca4106c1b5d101e8bf9d58dec09a4eae +size 193227 diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bcf045515776cb55c6b81ab47ce0d9dfbddfb20c --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Golgi apparatus", "1": "Endoplasmic reticulum", "2": "Mitochondria", "3": "Vesicles", "4": "Nuclear membrane", "5": "Lysosomes", "6": "Endosomes"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/plot_0.png b/protein_atlas_subcellular_location_all/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..edb882cadd9da4f2eab3a9dbd04b864154405ecc --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:30442ba0512c1f34b5b82b637b038953bc84e7b89ffb87a912f1960e821716d5 +size 144602 diff --git a/protein_atlas_subcellular_location_all/basic/plot_1.png b/protein_atlas_subcellular_location_all/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..686f98cae8f7555c2e48a3e5ddc09d80f7c75e4f --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:531da5b53065db8ad57082637a47a480fb4cdb97e28e207285c0c538a7468d58 +size 146921 diff --git a/protein_atlas_subcellular_location_all/basic/plot_2.png b/protein_atlas_subcellular_location_all/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6d647e860e62faae0feed8584ac45d127ab2c133 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4fdea80b97ed2debadfbf4968882b75c2486c82b7e347396ac84b2234bf49af1 +size 138589 diff --git a/protein_atlas_subcellular_location_all/basic/plot_3.png b/protein_atlas_subcellular_location_all/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..479f1f883a5f22021388263e0dd27dc65cfa6a81 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d28185910c7fa5d34b734d3aaf8c234ac2d2c84cb3fda34db2e5af130e1019e2 +size 136599 diff --git a/protein_atlas_subcellular_location_all/basic/plot_4.png b/protein_atlas_subcellular_location_all/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..87db47f68abf380a1a2df9259ee422029e290502 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83812919f0ab00baf799c19f5ba47ed47f2737e6edd7272e36bcd654ff283857 +size 142517 diff --git a/protein_atlas_subcellular_location_all/basic/plot_5.png b/protein_atlas_subcellular_location_all/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..6489a125f6c0f99f63cdb9cbd76e9bbf5748ee98 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:92852dfd03a0867b6683baa46eb691b94ec1eba2a91ff4939a06c332487141ef +size 138070 diff --git a/protein_atlas_subcellular_location_all/basic/plot_6.png b/protein_atlas_subcellular_location_all/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..cb66610aeecff2f28f442994921fbe833697a6dc --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21563b46c8c723d6485ba4e0805e9cc8a2cb57d7b8a99549651fbb47e7661ee2 +size 142220 diff --git a/protein_atlas_subcellular_location_all/consensus.joblib b/protein_atlas_subcellular_location_all/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..eff577dd69a266eab02b9520c2acd16b09f78b36 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2b5e8f8e62ceff9284e6ee319624b99243b129174710365f3540e997a9b13ba0 +size 97625 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..836e4f160f28d2d6d87104207f054d80f44e7230 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi apparatus 97 226 5.226123285654984 1.7310096317450118e-07 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 1.3745461288836005e-08 0.0330532662847291 0.0100401097122512 5.0928370487470114e-05 2.4071180086779583e-08 +Endoplasmic reticulum 85 209 4.782776222447432 1.7289056428726468e-06 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 1.5655461642564896e-18 0.0056186732669075 0.0001229367148022 1.4437247411468218e-11 6.887220664892491e-19 +Mitochondria 119 436 2.614073546156226 0.0089469774938151 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 2.5046249029159344e-18 5.869448364143601e-06 1.5391965753910162e-06 5.29493734656632e-10 7.205270519074015e-18 +Vesicles 98 349 2.4129172779961925 0.0158254108538429 63.69174757281554 303.19174757281553 0.3021616120018026 0.6308308858815788 16.21576692438533 35.60761931464484 1.2670437076534344 0.3993041904676221 0.0052726447813575 0.6753636900146418 0.3577303512746043 0.0667686942248098 0.0034848111164498 +Nuclear membrane 27 69 1.9688015817441704 0.0489758805998394 16.817961165048544 62.713592233009706 0.5402747034161678 0.5293388535672136 7.339768502370818 5.865441797870943 1.2287110387783358 0.3803813474041967 0.0547342095692904 0.5796059904208676 0.2548852757682844 0.4521663149592692 0.031879440669179 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5b62920fe7327aa25a872714306a9db1c57e9dda --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3549, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 166.24242424242425 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..03e0fe5e7b2ae5a196462945cb64230f2f227394 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C106/C106_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ef103c0f4671f3d3bd43a3ba46eb4bade335e052 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.4675187360061182 5.226123285654984 1.7310096317450118e-07 5.7123159638576945e-06 2.856165892395769e-06 226 P24390,P09601,P80303,P67812,P50897,O15258,Q9NXS2,Q9HC07,P55327,Q96CN9,Q9HB40,Q8NBJ4,Q86Y82,Q9NW68,P15291,Q5VW38,Q8NBN3,O60637,Q9UG56,Q9H2V7,O95302,O43493,O00461,O43752,Q9BRK5,O95070,P40616,Q96A49,O15127,O75071,A1L0T0,Q5BKZ1,Q99640,Q969S3,Q9H4A6,Q9NP58,Q8IZA0,Q8TAD4,Q16706,P10586,O15439,P16278,Q9H0U4,O60499,O75955,Q8N4A0,O95295,Q9NX62,Q9NTJ5,Q8NCH0,P11717,O60476,Q96HV5,O14681,Q96J42,Q9NWM8,Q04656,Q969M3,Q9HD45,Q8N6M0,Q96C57,Q6NTF9,Q9Y287,P50570,Q96RQ1,Q5KU26,Q14789,Q02818,P05067,O15260,Q9UID3,Q7RTS9,Q8IYS2,Q9BSR8,O95159,Q9NPR9,Q8TD16,Q93050,O14653,P04439,Q92859,Q9H9S5,Q92896,Q8NEY8,Q8TBA6,Q15043,Q6NUQ4,P53365,Q8N4Q0,Q15643,P49755,O43760,Q9UP83,Q9NP80,Q13190,O00231,Q9UBU6 97 +Endoplasmic reticulum 0.4389660933319873 4.782776222447432 1.7289056428726468e-06 5.705230799045283e-05 1.9017962071610113e-05 209 O43169,P43307,Q8NHH9,Q4ZIN3,P37268,Q70UQ0,O95197,P51648,Q9H3N1,Q14257,Q9P2W9,Q86UE4,Q96CN7,Q9Y680,O43731,P49257,Q15800,Q86XL3,Q13438,Q8N0U8,O15460,Q00765,Q96PC5,Q96G23,O00264,Q92791,Q96KA5,O96005,Q9NZ01,Q96CS3,Q9NQC3,P51572,Q5T9L3,Q9H0U4,O95470,Q5BJF2,Q96A33,P62820,Q9BUN8,Q9H3G5,Q8IV08,P21964,O14681,O95674,Q16850,Q9GZP9,Q86UP2,Q96HY6,Q13586,Q969M3,P04844,Q96KC8,O43852,Q8TCT9,Q99735,P04843,Q14849,O15260,Q9BRK0,Q8NF37,O43292,Q03518,Q86TM6,P27544,P50402,P51571,Q96A57,Q12981,Q15125,Q9BT22,Q9H6H4,O15269,Q8N5B7,Q9P035,P07237,Q15043,Q6NUQ4,P13674,O75845,Q9NR31,Q8WUJ1,Q6UW68,P27824,Q13217,Q96S66 85 +Mitochondria 0.3672576966620209 2.614073546156226 0.0089469774938151 0.2566430908462904 0.0590500514591798 436 Q8WY22,Q9Y2R0,O60830,Q8N4H5,P52789,Q9NS69,O14949,Q9UDX5,Q99595,O75027,Q8NBN7,Q96TA2,Q9Y6C9,P00374,Q9NZ45,Q9P2K2,Q96A26,Q69YU5,O75964,Q9P0J1,Q9H2D1,O14925,P21953,Q07021,Q96CU9,P57105,Q99623,Q9H4I3,Q3SXM5,Q8WWC4,Q13423,O15498,P50416,P13073,Q9UBX3,Q86UT6,Q9UII2,Q9NVH1,O95302,Q9Y512,Q9NR28,P45880,Q70HW3,Q9P0J0,Q8WVI0,Q7KZN9,Q7LGA3,P24539,P23786,Q86Y39,Q15070,Q16880,Q5XKP0,Q96E52,Q96EX1,Q96B49,Q13505,Q9NQZ5,Q9Y277,Q9NX40,Q6DKK2,Q9HCL2,Q96D53,O60313,Q07820,O60220,P12235,Q8NBM8,Q9BUR5,Q15388,Q16891,Q16740,Q6YN16,Q9Y255,Q9NVI7,O95139,Q9BZ95,Q8IYU8,Q7Z7H8,P12236,Q6UXV4,O43292,Q9NPL8,O43615,O95202,Q9H3K2,O75208,Q9NX63,Q7Z4V5,Q9BUB7,Q9H300,P56378,Q9Y3D6,Q8N2F6,Q5HYK3,Q96AY3,Q8NAN2,Q9H7Z7,Q5T9A4,Q9BPX6,P56385,O14548,Q53H12,P21912,Q9Y5L4,Q13084,P13674,P06576,P05141,Q9BW91,Q16836,Q9HC21,Q96I36,Q8IWA4,Q9NWS8,Q6NUK1,Q10713,Q9NWR8,Q12849 119 +Vesicles 0.3489226292763185 2.4129172779961925 0.0158254108538429 0.4092810940977326 0.087039759696136 349 Q96D71,P24390,P52789,P50897,Q9UMR5,P30519,Q9UEE9,P17900,Q8NBX0,Q8IW92,O15020,Q96ES6,P07602,Q86YN1,Q96CN7,Q86Y82,Q99538,O60506,P10253,Q3SXM5,P49257,Q9H2V7,O95302,P10619,Q9NRY5,Q5JRA6,O95070,O15460,O15127,P35613,A1L0T0,O95772,Q5BKZ1,Q9H2J7,Q9H4A6,Q96M27,Q92791,Q969X5,O00400,P16278,Q9H2C2,Q8TB61,O60499,Q9UJ14,Q8WTV0,P27105,Q9HD20,P21964,Q8N5M9,Q8TCT8,Q08722,Q8NCC3,Q9HD45,Q8TCD1,Q9Y287,P42785,Q5KU26,Q96RQ1,Q32P28,Q9NZC3,Q15363,Q14849,P05067,Q86WC4,Q9UPT5,Q14534,P06865,O15118,Q9UID3,O75312,Q9NW15,O75153,P16435,Q9BSR8,Q96L92,Q8N128,Q96ED9,P46020,Q96AA3,Q9NPR9,Q93050,P13473,Q9Y3C0,Q53H12,Q6UX07,P13674,O00754,Q8N4Q0,Q9Y487,Q9P0T7,P42345,P08236,Q9NWR8,O00429,P51790,Q06481,Q8IXH7,Q92564 98 +Nuclear membrane 0.4502488614915156 1.9688015817441704 0.0489758805998394 0.8093132409580199 0.2020255074743378 69 Q8WXH0,Q96G23,Q9UH99,P67812,Q9BTX1,Q8N5B7,Q5JTV8,O75976,O15260,Q5SNT2,O95168,P12270,O94919,Q8NFH5,Q9H1E5,Q9BW91,P50402,Q8IXM6,Q03252,O14735,Q6UW68,Q9Y6D9,Q9H8M7,O00560,P20700,Q14739,O94901 27 +Lysosomes 0.4765517742087022 1.38801504981459 0.1651324623972287 0.9974095216843436 0.4097288278740351 14 P02786,P09496,Q9UNH7,Q8IY95,O60749,O75436,Q8WTV0,O14964,O15400 9 +Lipid droplets 0.5181478938791313 1.2038845716351003 0.2286341957818511 0.9998096325872974 0.471558028800068 10 Q8NF37,Q96CS3,Q01105,Q969V3 4 +Centriolar satellite 0.3448488061255031 0.9453358334837648 0.3444874498169614 0.9999991145310008 0.57441374777873 31 O43169,Q13045,P41208,Q9UBK9 4 +Intermediate filaments 0.2698806243935494 0.2816578543499682 0.7782058739186237 1.0 0.9609307289806418 40 P08670,P07197,Q3SXM5,Q86YN1 4 +Endosomes 0.3163397944028778 0.2335489495866858 0.8153351639835749 1.0 0.9609307289806418 12 P02786,P09496,Q9UNH7,Q8IY95,O60749,O14964 6 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9c8e6f08a0fb40f826d80528fa716e2838cd43be --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACBD6", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKS1A", "ANLN", "ANO10", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARV1", "ARVCF", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD2B", "ATAD3A", "ATAD3B", "ATAD5", "ATF7IP", "ATG13", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP5S", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1G1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCR", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C14orf2", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf198", "C1orf35", "C2CD2", "C2CD5", "C5orf22", "C5orf51", "CAB39", "CACUL1", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CENPE", "CENPF", "CENPH", "CENPI", "CEP170", "CEP250", "CEP290", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLK3", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG5", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ5", "COQ8A", "COQ8B", "COQ9", "CORO1B", "COTL1", "COX14", "COX15", "COX4I1", "COX5B", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2NL", "CTU2", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDAH1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC6B", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA3", "EYA4", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM160B2", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGT7", "GHITM", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HIF1AN", "HIKESHI", "HINT2", "HIP1", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "ICE1", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS4", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KCTD21", "KCTD3", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5C", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLHDC4", "KMT2A", "KNL1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8C", "LRRFIP1", "LRWD1", "LSG1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM4", "LSM6", "LSM7", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "LZTFL1", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED13", "MED14", "MED16", "MED17", "MED20", "MED21", "MED23", "MED25", "MED4", "MEPCE", "MESD", "METAP2", "METTL1", "METTL13", "METTL16", "METTL9", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCOS", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL53", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI1", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA16", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NEO1", "NES", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NGEF", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME3", "NMT1", "NMT2", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2C2AP", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OSTM1", "OTUB1", "OTUD4", "OTUD6B", "OTULIN", "OXA1L", "OXNAD1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK3", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHLDB2", "PI4K2A", "PI4KA", "PI4KB", "PIAS1", "PIAS2", "PICALM", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCB3", "PLCG1", "PLCG2", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPIP5K2", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKAA2", "PRKAB1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTK2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURB", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPCTL", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB32", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEPK", "RABGAP1", "RABGEF1", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM33", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RICTOR", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2C", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPIA", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBF1", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP1", "SENP3", "SENP6", "SEPT10", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIN3B", "SIRT1", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLFN11", "SLIRP", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPIN1", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAMBPL1", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STRN3", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAB1", "TACC3", "TADA3", "TAF15", "TAF6", "TAF6L", "TAF7", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCC", "TBCEL", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM41A", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TST", "TTC1", "TTC19", "TTC21B", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTPAL", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC16", "TXNDC5", "TXNDC9", "TXNRD1", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UHRF1BP1", "ULBP3", "UMPS", "UNC45A", "UPF1", "UPF2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP22", "USP24", "USP28", "USP32", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VCPIP1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13C", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR4", "WDR41", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR77", "WDR82", "WIPI2", "WIZ", "WLS", "WNK1", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YES1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFPL1", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF106", "ZNF24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1", "ZZZ3"], "leading_proteins": ["ABCB6", "ABCB7", "ABCC4", "AGK", "ALDH3A2", "ALG1", "ANKLE2", "ANO10", "APLP2", "APOO", "APOOL", "APP", "ARFIP2", "ARL1", "ARMC10", "ARV1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP7A", "ATPIF1", "B4GALT1", "BCAP31", "BCKDHB", "BICD2", "BNIP1", "BRI3BP", "BSDC1", "BSG", "C12orf43", "C12orf73", "C14orf2", "C18orf32", "C19orf70", "C1QBP", "CALU", "CANX", "CCDC47", "CD47", "CDIPT", "CDS2", "CERS1", "CERS2", "CERS5", "CETN2", "CFDP1", "CHCHD3", "CHST14", "CISD1", "CLCC1", "CLCN3", "CLPP", "CLPTM1", "CLPTM1L", "CLTA", "CLUH", "COA3", "COG5", "COLEC12", "COMT", "COQ5", "COQ8B", "COQ9", "COX14", "COX15", "COX4I1", "COX7A2L", "CPD", "CPT1A", "CPT2", "CPVL", "CTSA", "CYB5B", "CYB5D2", "CYP51A1", "DCUN1D4", "DDRGK1", "DERL1", "DERL2", "DHFR", "DHRS13", "DIABLO", "DNAJC1", "DNAJC11", "DNAJC3", "DNM1L", "DNM2", "DOLPP1", "DYM", "EBP", "EFCAB14", "EI24", "EMD", "ENDOD1", "ERGIC1", "ERGIC2", "EXOC7", "FAF2", "FAM114A2", "FAM162A", "FAM177A1", "FAM8A1", "FDFT1", "FIS1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FKRP", "FLII", "FLOT1", "FOXRED1", "GAA", "GALNT4", "GCC1", "GDE1", "GGT7", "GHITM", "GLB1", "GLB1L2", "GLG1", "GM2A", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOSR2", "GPAA1", "GPAM", "GPR107", "GPR108", "GRSF1", "GUSB", "HACD3", "HADH", "HDGFL2", "HEXA", "HGS", "HK2", "HLA-A", "HM13", "HMOX1", "HMOX2", "HOOK2", "HS2ST1", "HSDL1", "HSDL2", "IGF2R", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "ISOC1", "ITM2B", "JAGN1", "KDELR1", "KDELR3", "KIAA0319L", "KIAA2013", "KTN1", "LAMP2", "LBR", "LETM1", "LGMN", "LMAN1", "LMNB1", "LMNB2", "LPCAT1", "MAD1L1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MCL1", "MCUB", "MFN1", "MFSD3", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIGA1", "MINDY3", "MRPL10", "MRPL28", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "NCLN", "NDC1", "NDUFA11", "NDUFA13", "NDUFB4", "NDUFB6", "NEFM", "NELFCD", "NEO1", "NLRX1", "NNT", "NPC1", "NRM", "NSD3", "NUCB1", "NUCB2", "NUDT9", "NUP35", "OCIAD1", "OMA1", "OPA1", "OS9", "OSTM1", "OTUD6B", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PARL", "PCYOX1L", "PDP1", "PGRMC1", "PHB2", "PHKA1", "PISD", "PKMYT1", "PLA2G15", "PLD3", "PMPCA", "PNPLA8", "POR", "PPHLN1", "PPT1", "PPT2", "PRCP", "PRELID1", "PRRC1", "PSAP", "PSMD11", "PTGES2", "PTPRF", "QPCTL", "RAB1A", "RAB1B", "RCN2", "RDH13", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RFT1", "RHBDD2", "RMND1", "RPN1", "RPN2", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1A", "SC5D", "SCAMP2", "SCARB1", "SCCPDH", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SET", "SGPL1", "SLC25A10", "SLC25A19", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC30A5", "SLC33A1", "SLC35B2", "SLC39A14", "SLC6A15", "SMIM12", "SMIM4", "SNAPIN", "SNX2", "SNX27", "SNX6", "SPNS1", "SPPL2A", "SPTBN2", "SPTLC1", "SQLE", "SSR1", "SSR4", "STARD3", "STARD3NL", "STARD7", "STIM1", "STOM", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "SUN1", "SUN2", "SURF4", "SYAP1", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYVN1", "TAP1", "TECR", "TFRC", "TGOLN2", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM8A", "TIMMDC1", "TM9SF3", "TMED10", "TMED2", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM214", "TMEM230", "TMEM259", "TMEM41A", "TMEM70", "TMEM87A", "TMEM9", "TMEM97", "TMX1", "TMX4", "TOMM20", "TOMM22", "TOMM5", "TOMM6", "TOR1AIP1", "TPD52", "TPR", "TRABD", "TRIP11", "TSPAN3", "TTC19", "TXNDC15", "TXNDC16", "UGT8", "UQCRQ", "UXT", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS26A", "VPS51", "WASHC3", "WLS", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YME1L1", "ZADH2", "ZFPL1", "ZNF326", "ZNF622", "ZPR1"]} \ No newline at end of file