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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c7d8f0d099663e7b6d1f977fbf1f9e2ddc60c041a027959ef13ad4c908fc83ba
+size 84291

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3549,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 3.0
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C107/C107_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9639029892837008	2.175043545450964	0.0296268533623249	0.8199015925713065	0.1640014487155715	3	Q9HB40,Q9H3G5	2
+Histidine acid phosphatase active site [IPR033379]	0.784705437239119	1.3897309646970653	0.1646105883224569	0.999964708421382	0.3138366506695876	3	Q9NPH0	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.6171677728336558	0.6536340641255781	0.5133475925070903	1.0	0.6096002661021698	4	P25705	1

interpro_active_site/selections.json

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+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "NCEH1", "NEK9", "NME1", "NME3", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PPIP5K2", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ACP6", "ATP5A1", "CPVL", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c68dfbed95597a9279b74a9eaf09db741609034a570c12de89c91d097a565b4f
+size 79391

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3549,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 5.258064516129032
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C107/C107_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,2 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.5228240934393038	0.296630461100305	0.7667486524122094	1.0	0.848900293742089	5	P22695	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "AURKA", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "CHEK1", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "LETM1", "LRP2", "MACF1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "ABC transporter-like, conserved site [IPR017871]", "3": "Proteasome beta-type subunit, conserved site [IPR016050]", "4": "14-3-3 protein, conserved site [IPR023409]", "5": "Guanylate kinase, conserved site [IPR020590]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:d33243322fb0bf9c18d0e2d001eb146c9f530617b8b92efc60831a2aedf7d065
+size 94544

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3549,
+    "annotations_size": 289,
+    "title": "Average number of proteins per term",
+    "value": 2.7993079584775087
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C107/C107_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tetraspanin, conserved site [IPR018503]	0.987309644670051	2.2744614635140645	0.0229382555780155	0.998776903532568	0.3224979374888614	3	O43657,Q9H1Z9	2
+Haem oxygenase conserved site [IPR018207]	0.9345926134761708	2.050224884321998	0.0403424907492735	0.9999932142029448	0.3224979374888614	2	P30519	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.924725119819566	2.007794879759815	0.0446650931729364	0.99999815930479	0.3224979374888614	2	Q99536	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.9106287003101192	1.9469385692157344	0.0515420999355509	0.9999997718508552	0.3224979374888614	2	P13473	1
+Sterol reductase, conserved site [IPR018083]	0.885537073583299	1.8379447763805188	0.0660705431771935	0.999999997365081	0.3292135685898091	2	Q14739	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8385093167701672	1.6244699736038355	0.104275543663304	0.9999999999999848	0.4069857210218862	7	Q13190,O15400,O60499,Q12846,O43752,Q9P2W9	6
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.8325345362278018	1.605264346545655	0.1084356419331669	0.999999999999996	0.4069857210218862	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.8325345362278018	1.605264346545655	0.1084356419331669	0.999999999999996	0.4069857210218862	2	P05067	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.8325345362278018	1.605264346545655	0.1084356419331669	0.999999999999996	0.4069857210218862	2	P05067	1
+Glycoside hydrolase, family 35, conserved site [IPR019801]	0.8215393290104127	1.5566602024496343	0.1195511821920678	1.0	0.4213450201647268	2	P16278	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8150549760360823	1.5279552290215808	0.1265236542397825	1.0	0.4340375065981398	2	Q9BTY2	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7664400035689227	1.3082598553366978	0.1907851864436036	1.0	0.5405580282568769	3	P55899	1
+Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]	0.7580401522950193	1.2708021992414678	0.2037990261614455	1.0	0.550447837015493	3	Q07954	1
+Intermediate filament protein, conserved site [IPR018039]	0.7300266366470687	1.1320422449228822	0.2576166742704431	1.0	0.5737358442712692	8	P20700,Q16352,P08670,P07197,Q03252,P07196	6
+Ras GTPase-activating protein, conserved site [IPR023152]	0.7171460800902356	1.089010916796698	0.2761490716053629	1.0	0.5825334430215321	3	Q13576,Q86VI3	2
+ABC transporter-like, conserved site [IPR017871]	0.7113377285195708	1.04928315414572	0.2940478169092446	1.0	0.5980997653650447	16	Q9NP58,O15439,O75027,O14678,P08183,P33527,P33897,Q99758,Q03518,Q9NUT2	10
+EGF-like calcium-binding, conserved site [IPR018097]	0.6822198487765441	0.930525257176118	0.3520991931865496	1.0	0.654503339875419	4	Q07954	1
+Clathrin adaptor complex, small chain [IPR000804]	0.6710917267531737	0.8820252559339984	0.3777631496627713	1.0	0.6603509509641579	4	P61923,P53680	2
+Heat shock protein Hsp90, conserved site [IPR019805]	0.6646926113931195	0.8595425800917047	0.3900412386428455	1.0	0.6603509509641579	3	P14625,P07900	2
+Mini-chromosome maintenance, conserved site [IPR018525]	0.6489051212904274	0.7766773783873256	0.4373491365389741	1.0	0.6863863464424912	6	Q14566,P49736,P33991	3
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.60631697687536	0.6154450854776358	0.538260824531889	1.0	0.7517151755452135	3	Q96CW1,Q9BXS5	2
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6060742700061494	0.6144684377139876	0.5389058235354027	1.0	0.7517151755452135	3	P09429	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.611266885853248	0.6112609492450324	0.5410268391467281	1.0	0.7517151755452135	8	P28074,P49721,P28070,Q99436,P28072	5
+Ribosomal protein L24e, conserved site [IPR023442]	0.5813363405695056	0.5235569050198813	0.6005867620340826	1.0	0.7860983209594082	2	Q9UHA3	1
+Ubiquitin interacting motif [IPR003903]	0.5672234850214459	0.4515473209299289	0.6515951275295093	1.0	0.8187434428522965	5	Q8IZ07,O14964	2
+Thioredoxin, conserved site [IPR017937]	0.5304058898795007	0.2976376012007307	0.7659797728799533	1.0	0.8480030476964795	10	Q9H1E5,Q96JJ7,Q9H3N1	3
+Ribosomal protein L24/L26, conserved site [IPR005825]	0.5148012404849323	0.29013610408022	0.7717121160698066	1.0	0.8480030476964795	2	Q96A35	1
+14-3-3 protein, conserved site [IPR023409]	0.4309906858594274	0.0578216846095278	0.9538906652535042	1.0	0.9845514366366526	6	P62258,P61981,Q04917,P31946,P63104	5
+Oxysterol-binding protein, conserved site [IPR018494]	0.427449602269651	0.0515817751248119	0.9588619413492276	1.0	0.9861605019570348	6	Q9BZF1,Q9BZF3	2
+DnaJ domain, conserved site [IPR018253]	0.4327700542258031	0.0384868393550459	0.9692995243839386	1.0	0.9933601508757386	11	Q96KC8	1
+Guanylate kinase, conserved site [IPR020590]	0.4163138583121568	0.0333034060253291	0.9734326376525492	1.0	0.994070785447303	6	O14936,Q00013,Q8N3R9,Q9NZW5,Q14168	5
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.3910346771919955	0.0186331849584366	0.9851337296586198	1.0	1.0	2	P06737	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCA3", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATAD2B", "ATM", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CDX2", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160B2", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGAV", "IVD", "KDM2A", "KDM5C", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NMT2", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN3", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCA3", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD1", "ABCD4", "ANKRD13A", "AP1M1", "AP2M1", "AP2S1", "APP", "CASK", "COPZ1", "DNAJC1", "FCGRT", "FUCA2", "GLB1", "HGS", "HMGB1", "HMOX2", "HSP90AA1", "HSP90B1", "INA", "IQGAP2", "IQGAP3", "LAMP2", "LBR", "LMNB1", "LMNB2", "LRP1", "MCM2", "MCM4", "MCM6", "MPP1", "MPP2", "MPP5", "MPP6", "MRPL24", "NEFL", "NEFM", "OSBPL6", "OSBPL8", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PYGL", "RSL24D1", "STX10", "STX18", "STX4", "STX5", "STX6", "STX7", "TAP1", "TMX1", "TMX3", "TMX4", "TSPAN10", "TSPAN6", "VAT1", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ABC transporter type 1, transmembrane domain [IPR011527]", "1": "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "2": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "3": "Intermediate filament, rod domain [IPR039008]", "4": "ABC transporter-like, ATP-binding domain [IPR003439]", "5": "Phospholipid/glycerol acyltransferase [IPR002123]", "6": "Target SNARE coiled-coil homology domain [IPR000727]", "7": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "8": "Immunoglobulin-like domain [IPR007110]", "9": "AP complex, mu/sigma subunit [IPR022775]", "10": "14-3-3 domain [IPR023410]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:77a6f403c3a26b6337179f6dea8fdfd74b56020795861a721715da68146040ad
+size 180109

interpro_domain/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3549,
+    "annotations_size": 2796,
+    "title": "Average number of proteins per term",
+    "value": 2.270743919885551
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C107/C107_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,248 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EXPERA domain [IPR033118]	0.9813927262475312	2.249462615226294	0.0244830787511673	1.0	0.500779974393541	2	Q15125	1
+MENTAL domain [IPR019498]	0.973216802932054	2.2149011124851965	0.0267668527411071	1.0	0.500779974393541	2	O95772	1
+Reticulon [IPR003388]	0.9706794474203532	2.204153665661746	0.0275135390703138	1.0	0.500779974393541	2	O95197	1
+Syntaxin 6, N-terminal [IPR015260]	0.9602480969833636	2.1598638694113066	0.0307832094915605	1.0	0.500779974393541	2	O43752	1
+START domain [IPR002913]	0.9534818156188304	2.1310451663326377	0.0330854214081053	1.0	0.500779974393541	2	Q14849	1
+Prenylcysteine lyase [IPR010795]	0.9481251762052398	2.1081806304723707	0.0350153680661071	1.0	0.500779974393541	2	Q9UHG3	1
+FAD-binding domain, PCMH-type [IPR016166]	0.9478432478150514	2.1069760252291116	0.0351196577912624	1.0	0.500779974393541	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.9478432478150514	2.1069760252291116	0.0351196577912624	1.0	0.500779974393541	2	Q15392	1
+BRICHOS domain [IPR007084]	0.9371299689878784	2.0611123906984754	0.0392923189871576	1.0	0.500779974393541	2	Q9NQX7	1
+Sterol-sensing domain [IPR000731]	0.9320552579644724	2.0393278872005416	0.041417314193644	1.0	0.500779974393541	2	O15118	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9210600507471124	1.9919992939256952	0.0463711353549149	1.0	0.500779974393541	2	Q8N2A8	1
+Fatty acid hydroxylase [IPR006694]	0.906681702847468	1.929849127310466	0.0536255343338356	1.0	0.500779974393541	2	Q15800	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.90378103837471	1.914330255598491	0.0555779708870305	1.0	0.500779974393541	5	Q96G23,P27544,Q15629,Q96CP7	4
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8942768536791554	1.876002684685084	0.0606549112494589	1.0	0.500779974393541	2	Q13505	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8942768536791554	1.876002684685084	0.0606549112494589	1.0	0.500779974393541	2	Q13505	1
+Band 3 cytoplasmic domain [IPR013769]	0.8894840710459566	1.855144273671732	0.0635756269222309	1.0	0.500779974393541	2	Q9Y6M7	1
+Bicarbonate transporter, C-terminal [IPR011531]	0.8894840710459566	1.855144273671732	0.0635756269222309	1.0	0.500779974393541	2	Q9Y6M7	1
+Peptidase M48 [IPR001915]	0.8849732168029227	1.8354861072770432	0.0664336956951721	1.0	0.500779974393541	2	O75844	1
+Ion transporter-like, CBS domain [IPR044751]	0.8782069354384017	1.8059514778808905	0.0709259191201152	1.0	0.500779974393541	2	Q8NE01	1
+CNNM, transmembrane domain [IPR002550]	0.8782069354384017	1.8059514778808905	0.0709259191201152	1.0	0.500779974393541	2	Q8NE01	1
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.8742599379757545	1.788697354882698	0.0736635691895619	1.0	0.50440249045366	2	P23634	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8731322244150013	1.7837642156340732	0.0744619865656042	1.0	0.50440249045366	2	Q9NVI7	1
+Marvel domain [IPR008253]	0.8703129405131138	1.7714248751008923	0.0764900751010797	1.0	0.50440249045366	2	O43760	1
+ERAP1-like C-terminal domain [IPR024571]	0.869741548579908	1.7652375759151393	0.0775238458628859	1.0	0.50440249045366	4	P55786,Q9UIQ6	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8567399887196709	1.7096144241854492	0.0873371965680909	1.0	0.5050787932739963	3	Q9Y282,Q96RQ1	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8567399887196709	1.7096144241854492	0.0873371965680909	1.0	0.5050787932739963	3	Q9Y282,Q96RQ1	2
+N-acetylgalactosaminyltransferase [IPR045885]	0.8526973831559934	1.691772092738184	0.090689436548955	1.0	0.5121025315788491	3	Q8N4A0	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8514237383704548	1.6885233733713256	0.0913108060661653	1.0	0.5121025315788491	2	Q15067	1
+PA domain [IPR003137]	0.8511418099802521	1.6872831860609154	0.0915489124891171	1.0	0.5121025315788491	2	Q8TCT8	1
+Peptidase M28 [IPR007484]	0.8517540632790654	1.6856335005872056	0.0918664125186394	1.0	0.5121025315788491	4	Q9NXS2,Q7Z2K6	2
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.8474767409078063	1.6711535725963913	0.0946913479350017	1.0	0.5121025315788491	2	Q9HCL2	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.8474767409078063	1.6711535725963913	0.0946913479350017	1.0	0.5121025315788491	2	Q9HCL2	1
+Tim44-like domain [IPR007379]	0.840992387933466	1.642584921183073	0.1004688426861331	1.0	0.5138308201623227	2	O43615	1
+NOPS [IPR012975]	0.8415115623237422	1.6423179417831697	0.1005241307367061	1.0	0.5138308201623227	3	Q8WXF1,P23246	2
+Major facilitator superfamily domain [IPR020846]	0.8389280677009937	1.628669752261371	0.1033829493335831	1.0	0.5138308201623227	4	Q7L0J3,Q9H2V7,Q14728	3
+Syntaxin, N-terminal domain [IPR006011]	0.8375634517766524	1.6248347769575289	0.104197768710373	1.0	0.5138308201623227	3	Q12846,O15400	2
+Tim10-like [IPR004217]	0.8361071932299073	1.6161211442210186	0.1060681235399443	1.0	0.5138308201623227	4	Q9Y5J6,Q9Y5L4,Q9Y5J9	3
+Potentiating neddylation domain [IPR005176]	0.8345080349591205	1.61397799576126	0.1065321992318724	1.0	0.5138308201623227	2	Q92564	1
+Peptidase S54, rhomboid domain [IPR022764]	0.8342261065689345	1.612733388871796	0.1068024432883114	1.0	0.5138308201623227	2	Q9H300	1
+Fatty acid desaturase domain [IPR005804]	0.8336622497885545	1.6102439740364791	0.1073446048983055	1.0	0.5138308201623227	2	O60427	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.8330983930081624	1.6077542926488804	0.1078890025605887	1.0	0.5138308201623227	2	P23786	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.8325345362278018	1.605264346545655	0.1084356419331669	1.0	0.5138308201623227	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.8325345362278018	1.605264346545655	0.1084356419331669	1.0	0.5138308201623227	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.8325345362278018	1.605264346545655	0.1084356419331669	1.0	0.5138308201623227	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.8325345362278018	1.605264346545655	0.1084356419331669	1.0	0.5138308201623227	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.8325345362278018	1.605264346545655	0.1084356419331669	1.0	0.5138308201623227	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.8325345362278018	1.605264346545655	0.1084356419331669	1.0	0.5138308201623227	2	P05067	1
+Glycosyl hydrolase family 38, C-terminal [IPR011682]	0.8319706794474229	1.6027741375733306	0.1089845286632953	1.0	0.5138308201623227	2	O00754	1
+Glycoside hydrolase family 38, N-terminal domain [IPR000602]	0.8319706794474229	1.6027741375733306	0.1089845286632953	1.0	0.5138308201623227	2	O00754	1
+Glycoside hydrolase family 38, central domain [IPR015341]	0.8319706794474229	1.6027741375733306	0.1089845286632953	1.0	0.5138308201623227	2	O00754	1
+Fibronectin type II domain [IPR000562]	0.8288694671553307	1.5890733729541695	0.1120438284841984	1.0	0.5166707572956476	2	Q9UBV2	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8250564334085737	1.5649194113500533	0.1176018065718593	1.0	0.5166707572956476	5	P23634,P16615,P05023,P20020	4
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8250564334085737	1.5649194113500533	0.1176018065718593	1.0	0.5166707572956476	5	P23634,P16615,P05023,P20020	4
+Glycoside hydrolase 35, catalytic domain [IPR031330]	0.8215393290104127	1.5566602024496343	0.1195511821920678	1.0	0.5181960246484889	2	P16278	1
+Arfaptin homology (AH) domain [IPR010504]	0.8156188328164662	1.530452412252218	0.125904784075145	1.0	0.5181960246484889	2	P53365	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.8150549760360823	1.5279552290215808	0.1265236542397825	1.0	0.5181960246484889	2	Q9BTY2	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.8049896746602154	1.4773752198716672	0.1395750848539054	1.0	0.5360593591431961	11	Q9NP58,O15439,O75027,O14678,P33527,P33897,P08183,Q03518,Q9NUT2	9
+MD-2-related lipid-recognition domain [IPR003172]	0.7995489145756784	1.4592121168491348	0.144506734850935	1.0	0.5376727152201101	2	P17900	1
+Zinc finger, CW-type [IPR011124]	0.7944742035522836	1.4366897059065986	0.1508061812577015	1.0	0.5392281669235561	2	Q8NB78	1
+Band 7 domain [IPR001107]	0.7965895939279258	1.4349074499983985	0.1513134724663023	1.0	0.5392281669235561	7	Q99623,O75955,Q9UJZ1,P27105	4
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7908269517407078	1.4170265864649274	0.1564751545401703	1.0	0.5439096913322825	3	Q32P28	1
+EH domain-containing protein, N-terminal [IPR031692]	0.7899633493092775	1.4166621398048185	0.1565817312367723	1.0	0.5439096913322825	2	Q9H4M9	1
+Domain of unknown function DUF5600 [IPR040990]	0.7899633493092775	1.4166621398048185	0.1565817312367723	1.0	0.5439096913322825	2	Q9H4M9	1
+Complement Clr-like EGF domain [IPR026823]	0.7871440654073891	1.4041419041596743	0.1602765975143709	1.0	0.5470642048397696	2	Q07954	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7856834934322543	1.385463453136556	0.1659108001911891	1.0	0.5514513808169224	8	O15173,O00264,Q9UMX5,O43169,O60427,Q8WUJ1	6
+Amino acid permease/ SLC12A domain [IPR004841]	0.7803777840428537	1.3740863154850878	0.1694148872858631	1.0	0.5514513808169224	2	P55011	1
+SLC12A transporter, C-terminal [IPR018491]	0.7803777840428537	1.3740863154850878	0.1694148872858631	1.0	0.5514513808169224	2	P55011	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7820453927682085	1.368878636347446	0.1710372147841221	1.0	0.5515338905334605	8	P23634,P05023,Q9HD20,Q04656,P16615,P20020	6
+Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]	0.7699464336058649	1.3277412275609208	0.1842636087232745	1.0	0.5715835428970838	2	Q96K12	1
+Fatty acyl-CoA reductase, C-terminal [IPR033640]	0.7699464336058649	1.3277412275609208	0.1842636087232745	1.0	0.5715835428970838	2	Q96K12	1
+Acyltransferase, C-terminal domain [IPR032098]	0.7649817779512913	1.3017561079201732	0.1929997725060324	1.0	0.5814950042315372	3	Q92604	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.7647390691114399	1.2971059936759313	0.1945947195393937	1.0	0.5837841586181813	4	P08670,P07196,P07197	3
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.7578235128277324	1.2738905435105796	0.2027022102448799	1.0	0.5928403554860713	2	Q8NF37	1
+MRH domain [IPR044865]	0.7590973201692695	1.2718465826641565	0.2034276342812533	1.0	0.5943402982762637	4	Q13438,P11717,P20645	3
+Immunoglobulin C1-set [IPR003597]	0.7533644624677549	1.2461892610845344	0.2126949206543531	1.0	0.6007904556794906	4	P04439,P55899	2
+ABC1 atypical kinase-like domain [IPR004147]	0.7513391598533767	1.245102463537701	0.2130940886969701	1.0	0.6007904556794906	2	Q96D53	1
+ADCK3-like domain [IPR034646]	0.7513391598533767	1.245102463537701	0.2130940886969701	1.0	0.6007904556794906	2	Q96D53	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.7521150592216554	1.2443928355192204	0.2133550184481401	1.0	0.6007904556794906	3	Q9BYT8,P52888	2
+Glycosyltransferase 2-like [IPR001173]	0.7536681715575434	1.244233436963712	0.2134136608937198	1.0	0.6007904556794906	5	Q10472,Q8N4A0,O60762,Q9Y673	4
+GOLD domain [IPR009038]	0.7518840217143836	1.2332394432608489	0.2174864434948031	1.0	0.6024671359718107	6	Q9Y3A6,P49755,Q9BVK6,Q15363	4
+Homeobox domain [IPR001356]	0.7494139685403802	1.2285168690890227	0.21925300081304	1.0	0.6024671359718107	4	Q96G23	1
+Lamin tail domain [IPR001322]	0.7484489565707728	1.228059717454174	0.2194245513204111	1.0	0.6024671359718107	3	P20700,Q03252	2
+Ricin B, lectin domain [IPR000772]	0.7416183822837925	1.1936687982228638	0.2326075503468767	1.0	0.6095320625771953	4	Q8N4A0	1
+STAG [IPR013721]	0.7383704539047095	1.1875878585682935	0.2349958235963387	1.0	0.6117396211740777	2	Q8WVM7	1
+Stromalin conservative domain [IPR020839]	0.7383704539047095	1.1875878585682935	0.2349958235963387	1.0	0.6117396211740777	2	Q8WVM7	1
+Longin domain [IPR010908]	0.7370246109673164	1.1772126905368427	0.2391106246646615	1.0	0.6129396338735076	3	P51809	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.7370246109673164	1.1772126905368427	0.2391106246646615	1.0	0.6129396338735076	3	P51809	1
+LEM-like domain [IPR013146]	0.7358330983929962	1.1763479457084385	0.239455863746594	1.0	0.6129396338735076	2	P42167	1
+Peptidase M41 [IPR000642]	0.7332957428813106	1.1651132166547695	0.2439731676694145	1.0	0.6138785424174025	2	Q96TA2	1
+Legume-like lectin [IPR005052]	0.7313222441499891	1.1563789450295945	0.2475261898991108	1.0	0.6156285243959062	2	Q12907	1
+SUN coiled coil domain 2 [IPR040994]	0.7301945305892168	1.151389530989931	0.2495720188242589	1.0	0.6156285243959062	2	Q9UH99	1
+Intermediate filament, rod domain [IPR039008]	0.7300266366470687	1.1320422449228822	0.2576166742704431	1.0	0.617905386714549	8	P20700,Q16352,P08670,P07197,Q03252,P07196	6
+GRIP domain [IPR000237]	0.7238929691612505	1.1188986126738476	0.2631833949053725	1.0	0.6231019700168	3	Q96CN9	1
+RasGAP protein, C-terminal [IPR000593]	0.7171460800902356	1.089010916796698	0.2761490716053629	1.0	0.635478995164634	3	Q13576,Q86VI3	2
+Patatin-like phospholipase domain [IPR002641]	0.7146884691288481	1.08292472442643	0.2788418365604124	1.0	0.6370699049198295	2	Q8IY17	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.7150821225129605	1.0798797531534148	0.2801957304167395	1.0	0.6370699049198295	3	Q9NUQ9	1
+Ribosomal protein L2, C-terminal [IPR022669]	0.7121511136171418	1.0717503407799072	0.28383218326846	1.0	0.6399957938859793	2	P62917	1
+Ribosomal Proteins L2, RNA binding domain [IPR022666]	0.7121511136171418	1.0717503407799072	0.28383218326846	1.0	0.6399957938859793	2	P62917	1
+EB1, C-terminal [IPR004953]	0.7096137581054437	1.0605854140055235	0.288878354141969	1.0	0.6448102196116755	2	Q15555	1
+MHC class I-like antigen recognition-like [IPR011161]	0.7104548203972512	1.050825267253557	0.2933388487347561	1.0	0.6448102196116755	5	P04439,P55899	2
+ABC transporter-like, ATP-binding domain [IPR003439]	0.7113377285195708	1.04928315414572	0.2940478169092446	1.0	0.6448102196116755	16	Q9NP58,O15439,O75027,O14678,P08183,P33527,P33897,Q99758,Q03518,Q9NUT2	10
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.7081218274111679	1.0491326432344577	0.294117074006119	1.0	0.6448102196116755	3	Q9UGJ1,Q9BSJ2	2
+Gamma tubulin complex component, C-terminal [IPR040457]	0.7081218274111679	1.0491326432344577	0.294117074006119	1.0	0.6448102196116755	3	Q9UGJ1,Q9BSJ2	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7103492486367335	1.043020459781552	0.2969388170224616	1.0	0.6448102196116755	8	Q99943,Q92604,Q9HCL2,Q8NF37,O15228,Q9NUQ2	6
+EGF-like domain [IPR000742]	0.7091150254971001	1.0410983098797246	0.2978299238878048	1.0	0.6448102196116755	6	Q07954,Q08431	2
+LEM domain [IPR003887]	0.7008384151681534	1.0041992632311765	0.3152825771835852	1.0	0.6549257695433167	6	P42167,Q86XL3	2
+Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]	0.6912884127431662	0.9802787357287932	0.3269485482010115	1.0	0.661467540354684	2	Q9UID3	1
+IPT domain [IPR002909]	0.691288412743142	0.9802787357286878	0.3269485482010634	1.0	0.661467540354684	2	O15031	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6957888060576751	0.9775565038981692	0.3282937188090136	1.0	0.6627503521949473	8	O60313,Q9H4M9,Q9H223,Q8IWA4	4
+Dynamin, N-terminal [IPR045063]	0.6957888060576751	0.9775565038981692	0.3282937188090136	1.0	0.6627503521949473	8	O60313,Q9H4M9,Q9H223,Q8IWA4	4
+Calcium uniporter protein, C-terminal [IPR006769]	0.6881872004510693	0.9667545784752248	0.3336667358341063	1.0	0.668289536813869	2	Q9NWR8	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.6873414152805262	0.963069941406548	0.3355124251222408	1.0	0.670904776173889	2	Q9NRG7	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.6871193272006897	0.9568801519815594	0.338627750321169	1.0	0.6727683322763056	3	P04439	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.6871193272006897	0.9568801519815594	0.338627750321169	1.0	0.6727683322763056	3	P04439	1
+Dynamin, GTPase domain [IPR001401]	0.6867915851246814	0.9505474398589812	0.3418341608423287	1.0	0.6727683322763056	4	O60313	1
+ELMO domain [IPR006816]	0.6805751339159923	0.9336544853227452	0.3504821501336685	1.0	0.6779339921596929	2	Q96JJ3	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.6848711136272306	0.9334157570443702	0.3506053478765794	1.0	0.6779339921596929	6	Q9NZ08,P55786,Q9UIQ6	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.6848711136272306	0.9334157570443702	0.3506053478765794	1.0	0.6779339921596929	6	Q9NZ08,P55786,Q9UIQ6	3
+FCP1 homology domain [IPR004274]	0.6800112771356113	0.9312083618004098	0.3517457933252048	1.0	0.6783870404977997	2	Q05D32	1
+EGF-like calcium-binding domain [IPR001881]	0.6822198487765441	0.930525257176118	0.3520991931865496	1.0	0.6783870404977997	4	Q07954	1
+BSD domain [IPR005607]	0.6804582973886669	0.9278245005651534	0.3534986127989632	1.0	0.6783870404977997	3	Q9NW68	1
+TAF6, C-terminal HEAT repeat domain [IPR011442]	0.6729630673808891	0.9007039818419468	0.3677457310130845	1.0	0.6882309664742866	2	P49848	1
+Ribosomal protein S7 domain [IPR023798]	0.6721172822103205	0.897052822823387	0.3696907310696025	1.0	0.6896572312525023	2	Q9Y2R9	1
+ERM family, FERM domain C-lobe [IPR041789]	0.6703327693175406	0.8838847594570143	0.3767584251655813	1.0	0.6907649552544035	3	P15311,P35241	2
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.6642232872850347	0.863079807490445	0.3880935892106718	1.0	0.6953870939723465	2	O60506	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.6643159379407558	0.8526774398279859	0.3938382049931521	1.0	0.7010758523588388	4	P14625,P07900,P08238	3
+Extracellular Endonuclease, subunit A [IPR020821]	0.6627706079215667	0.851271131226228	0.3946187575464979	1.0	0.7010758523588388	3	O94919	1
+DNA/RNA non-specific endonuclease [IPR001604]	0.6627706079215667	0.851271131226228	0.3946187575464979	1.0	0.7010758523588388	3	O94919	1
+FCH domain [IPR001060]	0.6602762898223796	0.8461684053161458	0.3974588045725906	1.0	0.7012649408779247	2	Q9UNF0	1
+F-BAR domain [IPR031160]	0.6602762898223796	0.8461684053161458	0.3974588045725906	1.0	0.7012649408779247	2	Q9UNF0	1
+Cyclic nucleotide-binding domain [IPR000595]	0.6548477563657693	0.8069371366473455	0.4197027017541452	1.0	0.7145034951692306	5	Q6P4Q7,P10644	2
+Ribosomal protein S4/S9, N-terminal [IPR001912]	0.6470256554835041	0.7898044455152705	0.4296419824459667	1.0	0.7214888786299838	2	Q9NV31	1
+GAR domain [IPR003108]	0.6444882999718131	0.7790897900391085	0.4359268240664198	1.0	0.7268046512162849	2	Q03001	1
+MCM N-terminal domain [IPR027925]	0.6489051212904274	0.7766773783873256	0.4373491365389741	1.0	0.7270084338662138	6	Q14566,P49736,P33991	3
+MCM domain [IPR001208]	0.6489051212904274	0.7766773783873256	0.4373491365389741	1.0	0.7270084338662138	6	Q14566,P49736,P33991	3
+MCM, AAA-lid domain [IPR041562]	0.6489051212904274	0.7766773783873256	0.4373491365389741	1.0	0.7270084338662138	6	Q14566,P49736,P33991	3
+MCM OB domain [IPR033762]	0.6489051212904274	0.7766773783873256	0.4373491365389741	1.0	0.7270084338662138	6	Q14566,P49736,P33991	3
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.644568911216138	0.7548281956308629	0.4503520737710542	1.0	0.7320839524789928	7	Q32P28,O60568	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.644568911216138	0.7548281956308629	0.4503520737710542	1.0	0.7320839524789928	7	Q32P28,O60568	2
+EH domain [IPR000261]	0.6424943566591318	0.7541216211009026	0.4507761957640097	1.0	0.7323476138037021	5	Q9H4M9,Q9H223,Q9UBC2,P42566	4
+CARG-binding factor, N-terminal [IPR012956]	0.6368762334367145	0.7471123507466177	0.4549957455353346	1.0	0.734932469391563	2	Q99729	1
+CBS domain [IPR000644]	0.6344780219048173	0.7086330584255826	0.4785522159800028	1.0	0.7464325816320603	8	Q8NE01,P51790,P51798,P51797	4
+Target SNARE coiled-coil homology domain [IPR000727]	0.6315722976838066	0.6908837061149569	0.4896386264606813	1.0	0.7538709248810932	10	Q13190,O15400,O60499,Q12846,O43752	5
+LRRC8, pannexin-like TM region [IPR021040]	0.6165773893431031	0.6632165932966724	0.5071918456997042	1.0	0.7606407327746477	2	Q8TDW0	1
+Chromo domain subgroup [IPR017984]	0.6175972927241891	0.6612468009648987	0.5084540520585896	1.0	0.7606407327746477	3	P83916,P45973	2
+Chromo shadow domain [IPR008251]	0.6175972927241891	0.6612468009648987	0.5084540520585896	1.0	0.7606407327746477	3	P83916,P45973	2
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.6171677728336558	0.6536340641255781	0.5133475925070903	1.0	0.7626566783474094	4	P25705	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.6171677728336558	0.6536340641255781	0.5133475925070903	1.0	0.7626566783474094	4	P25705	1
+Exportin-2, central domain [IPR013713]	0.614495205865752	0.6485735877748653	0.5166140320141233	1.0	0.7646653433094169	3	O95373,P55060	2
+Class II aldolase/adducin N-terminal [IPR001303]	0.6123375698992702	0.639792874499154	0.5223072656787757	1.0	0.7679164291378545	3	Q9UEY8	1
+BURAN domain [IPR045354]	0.6095291795883944	0.6346193619096723	0.5256766971995184	1.0	0.7679164291378545	2	Q8N163	1
+LAIKA domain [IPR045353]	0.6095291795883944	0.6346193619096723	0.5256766971995184	1.0	0.7679164291378545	2	Q8N163	1
+S1-like RNA binding domain [IPR025223]	0.6095291795883944	0.6346193619096723	0.5256766971995184	1.0	0.7679164291378545	2	Q8N163	1
+DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]	0.6095291795883944	0.6346193619096723	0.5256766971995184	1.0	0.7679164291378545	2	Q8N163	1
+FF domain [IPR002713]	0.6040609137055803	0.6063817180379705	0.5442613055933307	1.0	0.7760094902799352	3	O75400,Q13017	2
+BRK domain [IPR006576]	0.5985339723710115	0.5906344270041591	0.5547653925179974	1.0	0.7812325528513357	2	P51532	1
+p21 activated kinase binding domain [IPR033923]	0.5923315477868559	0.5661874405726667	0.571266366794837	1.0	0.7914848925064126	2	Q13177	1
+CRIB domain [IPR000095]	0.5924985899605125	0.5604832067024501	0.5751498910780308	1.0	0.792689288762069	3	Q9Y5S2,Q13177	2
+EF-hand, Ca insensitive [IPR014837]	0.5916525662718624	0.5571627353856223	0.5774162476568412	1.0	0.7929547291004557	3	O43707,Q13813	2
+Immunoglobulin I-set [IPR013098]	0.589619166181907	0.5430849957146888	0.5870712828233824	1.0	0.7958892495397069	4	P10586	1
+Ras GTPase-activating domain [IPR001936]	0.5841758053079849	0.5218958967369172	0.6017428154030073	1.0	0.8053963197064665	4	Q13576,Q86VI3	2
+Rad60/SUMO-like domain [IPR022617]	0.5700592049619394	0.4808568068716778	0.6306182729440948	1.0	0.8170002356595882	2	P61956	1
+KASH domain [IPR012315]	0.5697772765717639	0.4798034694649631	0.6313671456192986	1.0	0.8170002356595882	2	Q8WXH0	1
+NET domain [IPR027353]	0.5635748519875978	0.4568136468224518	0.6478049960127177	1.0	0.8226299817031724	2	P25440	1
+Brdt, bromodomain, repeat II [IPR043509]	0.5635748519875978	0.4568136468224518	0.6478049960127177	1.0	0.8226299817031724	2	P25440	1
+Brdt, bromodomain, repeat I [IPR043508]	0.5635748519875978	0.4568136468224518	0.6478049960127177	1.0	0.8226299817031724	2	P25440	1
+Zinc finger, CHHC-type [IPR012996]	0.5638332971960105	0.4512389006584087	0.6518173755893546	1.0	0.8233562334225581	3	P55795	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.5631697687535371	0.4487965163110337	0.6535784520260943	1.0	0.8233562334225581	3	Q10567,O00203	2
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5600681809099777	0.3958924226101303	0.692184391236289	1.0	0.8338421188697389	12	Q96AY3,Q9NWM8,O95302,Q5T1M5,P26885,Q9Y680	6
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.5497767481570854	0.3940967655301931	0.6935095989145914	1.0	0.8339329463317801	4	Q96RL7	1
+Immunoglobulin-like domain [IPR007110]	0.5595414895068034	0.3881923019575283	0.697873729524503	1.0	0.8339329463317801	14	P55899,P10586,P04439,Q08722,Q92859,P35613	6
+RNA-binding S4 domain [IPR002942]	0.5432642791236566	0.3775959649967553	0.7057307626305316	1.0	0.8349782073952401	3	Q9NV31	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.5424541607898462	0.3684349768701323	0.7125489210796063	1.0	0.8361242866437384	4	Q9Y597,Q96CX2,Q4G0X4	3
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.5397606093420608	0.36550341295619	0.714735659618488	1.0	0.8365010064015455	3	P28340	1
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.5397606093420608	0.36550341295619	0.714735659618488	1.0	0.8365010064015455	3	P28340	1
+AP complex, mu/sigma subunit [IPR022775]	0.5456684617444748	0.3630164032713412	0.716592630946882	1.0	0.8365732760448776	7	P61966,P53680,Q9Y2T2,P61923,Q96CW1	5
+Vps16, C-terminal [IPR006925]	0.5305892303355109	0.3410921514177537	0.733034209586962	1.0	0.842256336713224	2	Q9H269	1
+CTP synthase, N-terminal [IPR017456]	0.5260783760924843	0.3262166259711347	0.7442604631474066	1.0	0.8436385728455699	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.5260783760924843	0.3262166259711347	0.7442604631474066	1.0	0.8436385728455699	2	Q9NRF8	1
+EF hand associated, type-2 [IPR013567]	0.5224133070200333	0.3143140007017278	0.7532825656562194	1.0	0.8511154327859308	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.5224133070200333	0.3143140007017278	0.7532825656562194	1.0	0.8511154327859308	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.5224133070200333	0.3143140007017278	0.7532825656562194	1.0	0.8511154327859308	2	Q8IXI1	1
+RNA polymerase, alpha subunit [IPR000722]	0.5180485053581642	0.2938169512162453	0.7688977813200677	1.0	0.8585615801002034	3	P24928,O95602	2
+RNA polymerase Rpb1, domain 1 [IPR007080]	0.5180485053581642	0.2938169512162453	0.7688977813200677	1.0	0.8585615801002034	3	P24928,O95602	2
+RNA polymerase Rpb1, domain 5 [IPR007081]	0.5180485053581642	0.2938169512162453	0.7688977813200677	1.0	0.8585615801002034	3	P24928,O95602	2
+RNA polymerase Rpb1, domain 4 [IPR007083]	0.5180485053581642	0.2938169512162453	0.7688977813200677	1.0	0.8585615801002034	3	P24928,O95602	2
+RNA polymerase Rpb1, domain 3 [IPR007066]	0.5180485053581642	0.2938169512162453	0.7688977813200677	1.0	0.8585615801002034	3	P24928,O95602	2
+RNA polymerase, N-terminal [IPR006592]	0.5180485053581642	0.2938169512162453	0.7688977813200677	1.0	0.8585615801002034	3	P24928,O95602	2
+Ribosomal protein L26/L24, KOW domain [IPR041988]	0.5148012404849323	0.29013610408022	0.7717121160698066	1.0	0.8610163912734154	2	Q96A35	1
+Citron homology (CNH) domain [IPR001180]	0.516638465877062	0.2893658689745877	0.7723014108934205	1.0	0.8613301734575204	3	Q9Y5S2,Q8WUH2	2
+Mu homology domain [IPR028565]	0.5170218032148687	0.2842334988576372	0.7762314452749568	1.0	0.8614700087085205	4	Q96CW1,Q9BXS5	2
+RNA recognition motif domain, eukaryote [IPR003954]	0.5299078953977241	0.2816329480548796	0.7782249735143305	1.0	0.8627743956962998	14	Q14498	1
+Heat shock chaperonin-binding [IPR006636]	0.5004958390560978	0.2340437999054366	0.814950975376691	1.0	0.8904270915018476	4	P54727	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.4942204680011473	0.228652756612666	0.8191388167477327	1.0	0.8937720113288337	2	Q9Y678	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.4942204680011473	0.228652756612666	0.8191388167477327	1.0	0.8937720113288337	2	Q9Y678	1
+NUC153 [IPR012580]	0.4933746828305776	0.2262532814682951	0.8210044322105503	1.0	0.8949428430645998	2	Q9H501	1
+Dilute domain [IPR002710]	0.49111925570906	0.2199055144438405	0.8259447415297247	1.0	0.8996266058890184	2	P55196	1
+Immunoglobulin subtype 2 [IPR003598]	0.5022803173333025	0.2176544264142903	0.8276983747762645	1.0	0.9004843018966675	8	P10586,P35613	2
+Peptidase M16, C-terminal [IPR007863]	0.4932693579669348	0.1965020103064642	0.8442172593439203	1.0	0.916316559443168	7	Q10713,P22695	2
+Peptidase M16, N-terminal [IPR011765]	0.4932693579669348	0.1965020103064642	0.8442172593439203	1.0	0.916316559443168	7	Q10713,P22695	2
+Clp ATPase, C-terminal [IPR019489]	0.4795601917113101	0.1885557626451349	0.8504410070650779	1.0	0.9209268225228342	2	Q9H078	1
+SAB domain [IPR007477]	0.4811054709532063	0.1863245499376041	0.8521902564863715	1.0	0.9221067945572348	3	P11171,Q9Y2J2	2
+Band 4.1, C-terminal [IPR008379]	0.4811054709532063	0.1863245499376041	0.8521902564863715	1.0	0.9221067945572348	3	P11171,Q9Y2J2	2
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.4827005955835927	0.1843999770769871	0.8536996878001357	1.0	0.9233827184097404	4	Q16134	1
+Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]	0.4794134235758762	0.1818808573474368	0.8556762275453302	1.0	0.9248050762337624	3	Q14241,Q96QC0	2
+THUMP domain [IPR004114]	0.473075838736982	0.1718564739461585	0.8635503661412329	1.0	0.9300796701582772	2	Q9BV44	1
+ZU5 domain [IPR000906]	0.4708204116154662	0.1662006516062912	0.8679990466719476	1.0	0.9334328209595252	2	Q07157	1
+Ku70/Ku80, N-terminal alpha/beta [IPR005161]	0.4688469128841492	0.1613170544034257	0.8718436917040906	1.0	0.9354086577147496	2	P12956	1
+Ku70/Ku80 C-terminal arm [IPR005160]	0.4688469128841492	0.1613170544034257	0.8718436917040906	1.0	0.9354086577147496	2	P12956	1
+Ku70/Ku80 beta-barrel domain [IPR006164]	0.4688469128841492	0.1613170544034257	0.8718436917040906	1.0	0.9354086577147496	2	P12956	1
+Zinc finger, RanBP2-type [IPR001876]	0.4825483584374076	0.1578931345516004	0.8745410080384672	1.0	0.9375830745688476	9	Q92804,Q01844,P98175,P35637	4
+Ribosomal protein L18e/L15P [IPR021131]	0.4661590524534731	0.1486156942499898	0.8818568883218172	1.0	0.9421749559601836	3	Q9P015,P46776	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.4601071327882808	0.1404292117139517	0.888320878917678	1.0	0.9479943425396288	2	P51114	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.4602368866328336	0.134653148351046	0.8928861179151315	1.0	0.9503272119111944	3	Q06787,P51114	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.4602368866328336	0.134653148351046	0.8928861179151315	1.0	0.9503272119111944	3	Q06787,P51114	2
+Fxr1, tudor domain [IPR041560]	0.4602368866328336	0.134653148351046	0.8928861179151315	1.0	0.9503272119111944	3	Q06787,P51114	2
+Agenet-like domain [IPR008395]	0.4602368866328336	0.134653148351046	0.8928861179151315	1.0	0.9503272119111944	3	Q06787,P51114	2
+SUN domain [IPR012919]	0.4562380013173205	0.1255447162405016	0.9000923266088141	1.0	0.9532796004538804	3	Q9UH99	1
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.4554118317258532	0.1178202612650197	0.906210075196185	1.0	0.956850551343691	4	Q99536	1
+Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]	0.4471384268395951	0.1116910245195047	0.911068396195002	1.0	0.9608321137800824	2	Q9UKA9	1
+Immunoglobulin subtype [IPR003599]	0.4584362843778037	0.0990237566893736	0.921119407693878	1.0	0.9681645141082154	9	P10586,P35613	2
+Kinesin-associated [IPR032405]	0.4454283575299517	0.0964772288009176	0.9231415583358332	1.0	0.9692466380424294	4	Q15058	1
+Guanylate kinase-like domain [IPR008144]	0.4518375559855078	0.0892144309072316	0.9289114969045852	1.0	0.972839034693079	8	Q9UDY2,Q8N3R9,Q07157,Q14168	4
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4518375559855078	0.0892144309072316	0.9289114969045852	1.0	0.972839034693079	8	Q9UDY2,Q8N3R9,Q07157,Q14168	4
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.4458757012565349	0.0863347936615822	0.9312002803802246	1.0	0.9743029370434456	6	Q14141,Q9P0V9,Q15019,Q16181	4
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.4394663154805781	0.0845148689030424	0.9326470814611784	1.0	0.9743029370434456	4	O60749	1
+PWI domain [IPR002483]	0.4384875846501065	0.0771037907693981	0.9385409773824906	1.0	0.9743029370434456	5	Q9P2N5,O43395,Q5T8P6,Q8IYB3	4
+Bms1/Tsr1-type G domain [IPR030387]	0.4268395827459866	0.0721992354873321	0.9424433535804182	1.0	0.975591120551962	2	Q2NL82	1
+AARP2CN [IPR012948]	0.4268395827459866	0.0721992354873321	0.9424433535804182	1.0	0.975591120551962	2	Q2NL82	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.4268395827459866	0.0721992354873321	0.9424433535804182	1.0	0.975591120551962	2	Q2NL82	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.4268556235991787	0.0666287016205005	0.9468772959214942	1.0	0.9775254568494652	3	P61289	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.4268556235991787	0.0666287016205005	0.9468772959214942	1.0	0.9775254568494652	3	P61289	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.4249858996051986	0.063357791593252	0.9494815971176588	1.0	0.9788903191522766	3	A0FGR8,Q9BSJ8	2
+14-3-3 domain [IPR023410]	0.4309906858594274	0.0578216846095278	0.9538906652535042	1.0	0.9823492817859292	6	P62258,P61981,Q04917,P31946,P63104	5
+Far upstream element-binding protein, C-terminal [IPR015096]	0.4152805187482396	0.0526998779246351	0.957971036294224	1.0	0.9861881507653352	2	Q96AE4	1
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.4093600225542766	0.0435396454060975	0.9652713620115	1.0	0.9929723061751856	2	Q99707	1
+L27 domain [IPR004172]	0.4161963882618388	0.0382202716801709	0.9695120582398586	1.0	0.9966013657495018	5	O14936,Q9NZW5,Q8N3R9,Q14168	4
+L27 domain, C-terminal [IPR014775]	0.4161963882618388	0.0382202716801709	0.9695120582398586	1.0	0.9966013657495018	5	O14936,Q9NZW5,Q8N3R9,Q14168	4
+Spen paralogue/orthologue C-terminal, metazoa [IPR010912]	0.4042853115308787	0.036126711331619	0.9711813236632728	1.0	0.9979503788910364	2	Q96T37	1
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.4155149485355747	0.0320697197095567	0.9744164511552416	1.0	1.0	6	Q12874	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.3981951494641824	0.0226311271085881	0.9819445143397164	1.0	1.0	3	Q969Z0,Q9NYY8	2
+RAP domain [IPR013584]	0.3981951494641824	0.0226311271085881	0.9819445143397164	1.0	1.0	3	Q969Z0,Q9NYY8	2
+FAST kinase leucine-rich [IPR010622]	0.3981951494641824	0.0226311271085881	0.9819445143397164	1.0	1.0	3	Q969Z0,Q9NYY8	2
+Fibronectin type III [IPR003961]	0.4105878606427878	0.0201543088747795	0.9839202767095224	1.0	1.0	7	P10586,Q92859	2
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.3806033267550048	0.0066864007340406	0.994665063839345	1.0	1.0	2	Q9Y305	1
+Ubiquitin system component CUE [IPR003892]	0.3839210155148027	0.0006219307174056	0.999503771114683	1.0	1.0	4	Q9Y679,Q9H1I8,Q9H0E2	3
+FERM adjacent (FA) [IPR014847]	0.3836389280676976	0.0003163127811585	0.9997476189197376	1.0	1.0	4	P11171,O43491,Q9Y2J2	3

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}