msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Regulation of innate immune responses to cytosolic dna	0.8531500332219574	1.8881214946587332	0.0590096418527865	1.0	1.0	5	P19474	1
Bmal1 clock npas2 activates circadian gene expression	0.9149520773311076	1.838354899220492	0.0660101263310666	1.0	1.0	3	P43490	1
Maturation of sars cov 2 nucleoprotein	0.7673491434327737	1.8236805359549275	0.0682003831158493	1.0	1.0	6	Q96SB4,P49841,P78362	3
Sting mediated induction of host immune responses	0.7388060974553199	1.8141071182683728	0.0696612358825925	1.0	1.0	7	P19474	1
Interleukin 37 signaling	0.8218868344091096	1.76847608105138	0.0769813474428671	1.0	1.0	5	P43378	1
Polo like kinase mediated events	0.7240790881450923	1.7508581512302792	0.079970346904691	1.0	1.0	7	Q5TKA1,P49454,P14635	3
Antimicrobial peptides	0.892194323144107	1.7497166371470727	0.0801672214266857	1.0	1.0	3	P35030,P81605	2
Sumoylation of transcription factors	0.7048987139598093	1.6680550471453657	0.0953047997396483	1.0	1.0	7	O75928,P42771	2
Met activates ras signaling	0.7298592876756017	1.6672256198332034	0.0954695502110611	1.0	1.0	6	Q96S59,Q9NWH9	2
Keratinization	0.7023253948175813	1.6569118568028784	0.0975372968484458	1.0	1.0	7	P15924	1
Formation of the cornified envelope	0.7023253948175813	1.6569118568028784	0.0975372968484458	1.0	1.0	7	P15924	1
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1	0.7807807807807872	1.540721370083812	0.1233846134543741	1.0	1.0	4	O14733,O43318,P61088	3
Cohesin loading onto chromatin	0.6758370798227568	1.5025171520182072	0.1329636016676691	1.0	1.0	9	Q6KC79,Q14683,Q9Y6X3,Q8N3U4,Q9NTI5,O60216	6
Formation of senescence associated heterochromatin foci sahf	0.6680147055870416	1.4685576834491008	0.1419527996729499	1.0	1.0	9	Q9Y6J0	1
Activation of smo	0.8190502183406152	1.4617256369875475	0.1438164089746467	1.0	1.0	3	Q9Y496,P32121	2
Condensation of prometaphase chromosomes	0.6649504417263099	1.4552453111480874	0.1456013608844726	1.0	1.0	9	P67870,Q9BPX3,P19784,O95347,P14635,Q9NTJ3	6
Nod1 2 signaling pathway	0.6629268301677249	1.44645138679735	0.1480506377161536	1.0	1.0	9	O15111,Q13685,Q15750,O43318,P61088,Q14790	6
Wnt mediated activation of dvl	0.8032205240174701	1.398975018753949	0.161820474430034	1.0	1.0	3	O14641,P67870	2
Defects in biotin btn metabolism	0.6417628680118264	1.3929198835122136	0.1636440189868904	1.0	1.0	7	P50747,P05165,P11498	3
Establishment of sister chromatid cohesion	0.6404591689347208	1.387212367850887	0.1653770152237768	1.0	1.0	7	Q14683,Q8N3U4,Q9NTI5,O60216	4
Mismatch repair	0.6613737595051039	1.3824473218813775	0.1668343945640074	1.0	1.0	12	Q9UQ84	1
Activated tak1 mediates p38 mapk activation	0.740263956913484	1.380370426149793	0.1674726210366564	1.0	1.0	4	O43318,P61088	2
Resolution of d loop structures	0.6413533367255364	1.333614293287824	0.1823302961868367	1.0	1.0	10	Q9UQ84	1
Resolution of d loop structures through synthesis dependent strand annealing sdsa	0.6413533367255364	1.333614293287824	0.1823302961868367	1.0	1.0	10	Q9UQ84	1
Traf6 mediated induction of tak1 complex within tlr4 complex	0.7805676855895234	1.309080643671293	0.1905070351969473	1.0	1.0	3	O43318,Q6SZW1	2
Ikk complex recruitment mediated by rip1	0.7207780846897576	1.3030286432835392	0.192564982885639	1.0	1.0	4	O15111,P61088	2
Glycogen synthesis	0.7007634428549407	1.2962986580141775	0.1948726107544789	1.0	1.0	5	Q96G03,P46976,P13807	3
Activation of nima kinases nek9 nek6 nek7	0.7156178901713373	1.282541026896184	0.1996529225247865	1.0	1.0	4	P14635,P53350	2
Sumoylation of intracellular receptors	0.7735143060850812	1.281088225182357	0.200162679209797	1.0	1.0	3	O75928	1
Interconversion of nucleotide di and triphosphates	0.6695311124420902	1.271291807596567	0.2036248557480497	1.0	1.0	20	Q9H773	1
Glutathione synthesis and recycling	0.6341674202927251	1.2620719158504874	0.2069229098064147	1.0	1.0	6	O75223	1
Diseases of dna repair	0.6385979460668997	1.2475597368347406	0.2121923310685987	1.0	1.0	14	Q9UQ84,P20585	2
Ncam signaling for neurite out growth	0.6094990558665162	1.2327620637252017	0.2176645488164514	1.0	1.0	8	P28482,O15020,Q13813,P62993,Q01082,P06241	6
Mitotic telophase cytokinesis	0.6227361195507667	1.2159758259416813	0.2239941309565447	1.0	1.0	12	Q6KC79,Q14683,Q9Y6X3,P53350,Q8N3U4,Q9NTI5,O60216	7
Apoptosis induced dna fragmentation	0.6127372003332408	1.2095791775036382	0.2264404121406316	1.0	1.0	10	P09429,O76075	2
Vxpx cargo targeting to cilium	0.6073055324912056	1.2045492326733405	0.2283773651941527	1.0	1.0	9	Q96A65,Q8TAG9,Q8IYI6,Q92538,P18085	5
Met activates ptk2 signaling	0.6953459934972427	1.202091223097498	0.2293281865162053	1.0	1.0	4	P07942	1
Phosphorylation of emi1	0.7491812227074276	1.1846158904479365	0.2361693513294656	1.0	1.0	3	P14635,P53350	2
Transcriptional activation of mitochondrial biogenesis	0.6235915762464319	1.1834458643367831	0.2366324895100469	1.0	1.0	14	P48735,Q8WVM0	2
Activation of irf3 irf7 mediated by tbk1 ikk epsilon	0.7468801849580485	1.1755067675770123	0.2397920312410644	1.0	1.0	3	Q9UHD2	1
Interaction between l1 and ankyrins	0.6855036855036887	1.163083449375918	0.2447956464374416	1.0	1.0	4	Q01082,O15020,Q13813	3
Adherens junctions interactions	0.5839411368559472	1.121599356847608	0.262032825234316	1.0	1.0	8	P14923,P55196,Q9BY67,P35221	4
G0 and early g1	0.5775249478592821	1.1120754925714338	0.2661056929234031	1.0	1.0	7	Q5TKA1,P12004,P06493,P11388	4
Dap12 signaling	0.5752428204530862	1.1021556187602102	0.2703940227809402	1.0	1.0	7	P29353,O00459,P06241,P19174	4
Disassembly of the destruction complex and recruitment of axin to the membrane	0.5824531403368685	1.096978102756867	0.2726509644328208	1.0	1.0	9	O14641,Q14738,P49841,Q13362,P48729	5
Raf independent mapk1 3 activation	0.566629970200246	1.0647893660240386	0.2869712583868784	1.0	1.0	7	P28482,P27361,Q02750,P06493,P36507	5
Small interfering rna sirna biogenesis	0.6595619628432241	1.0606076688792223	0.2888682359280023	1.0	1.0	4	Q9UPY3,Q99598	2
Translesion synthesis by polk	0.5770547108492992	1.0558707870024762	0.2910272522575421	1.0	1.0	10	P35251,P41440,P35244,P12004,P15927,P40938	6
Biotin transport and metabolism	0.5726810064305887	1.0549124953892444	0.2914653469251682	1.0	1.0	9	P50747,O00763,P05165,P11498	4
Met promotes cell motility	0.5684026512341104	1.036550546838006	0.2999453707911104	1.0	1.0	9	P46108,P07942	2
Signaling by pdgfr in disease	0.5599553810425092	1.0359212090045602	0.3002389021446232	1.0	1.0	7	O43815,O00459,Q6UN15,P42224	4
Dna damage reversal	0.5801693526358889	1.033602110894612	0.3013222121577961	1.0	1.0	6	Q8N3C0,Q6P6C2,Q8N9N2,P16455,Q9H1I8	5
Regulation of tp53 expression and degradation	0.5800688013052415	1.0335600925042785	0.3013418640000638	1.0	1.0	12	Q9UER7,Q13362	2
Platelet sensitization by ldl	0.5581015689220837	1.0279188569959925	0.3039879985136928	1.0	1.0	7	Q14738,Q13362	2
Beta catenin phosphorylation cascade	0.5602155229277177	1.0191754138248983	0.3081196966666422	1.0	1.0	8	P48729,Q14738,P49841,Q13362	4
Signaling by ctnnb1 phospho site mutants	0.5602155229277177	1.0191754138248983	0.3081196966666422	1.0	1.0	8	P48729,Q14738,P49841,Q13362	4
Cell cell junction organization	0.5702368347820225	1.009248251867524	0.3128555909540165	1.0	1.0	11	P14923,Q8TEW0,P55196,P35221,Q9BY67	5
Signaling by alk	0.5528380099903031	1.0052379487577632	0.3147822860555034	1.0	1.0	7	Q96ST3,P19174,O00459,P29353,Q13547	5
Synthesis of udp n acetyl glucosamine	0.6261605679956245	1.004515127986017	0.3151303831733378	1.0	1.0	5	Q9UJ70,O94808,O95394,Q06210	4
Processing and activation of sumo	0.6420530872101909	0.9918805896689832	0.3212557787657455	1.0	1.0	4	Q9P0U3	1
Synthesis of pips at the late endosome membrane	0.6418188970750024	0.9909645119931424	0.3217029092529251	1.0	1.0	4	O00443,Q08AM6	2
Myoclonic epilepsy of lafora	0.8761255115961768	0.9875222364258736	0.3233866873989641	1.0	1.0	2	P46976	1
Uptake and function of anthrax toxins	0.639809720598175	0.9831091270893494	0.3255537327130842	1.0	1.0	4	O14733,Q02750	2
Constitutive signaling by aberrant pi3k in cancer	0.5517398264155707	0.9828597035034838	0.3256764928157563	1.0	1.0	8	P84095,O00459,P62993,P06241,Q9NWH9,O43815	6
Uptake and actions of bacterial toxins	0.5506023791976923	0.977999550956067	0.328074546175221	1.0	1.0	8	Q16881,Q02750	2
Receptor mediated mitophagy	0.6381097452061582	0.9764681904515778	0.3288325037861472	1.0	1.0	4	P67870	1
Apoptotic cleavage of cell adhesion proteins	0.564582344849655	0.9683991759392974	0.3328450508717862	1.0	1.0	6	P15924,Q07157	2
Ticam1 rip1 mediated ikk complex recruitment	0.6931601373172289	0.9643449097453924	0.3348730321365145	1.0	1.0	3	P61088	1
Irak1 recruits ikk complex	0.6931601373172289	0.9643449097453924	0.3348730321365145	1.0	1.0	3	P61088	1
Nephrin family interactions	0.5536464788956674	0.9562626677704458	0.3389395458803623	1.0	1.0	10	P46940,Q13813,O00459,Q9Y5K6,P12814,Q01082,P06241	7
Sema4d in semaphorin signaling	0.5482192371371221	0.9504892808174412	0.341863697951891	1.0	1.0	9	P35579,Q9NWH9,O75116	3
Signaling by wnt in cancer	0.5513697024921774	0.946649533859698	0.3438173942064817	1.0	1.0	10	Q14738,P49841,P56545,Q13362,P48729	5
Generation of second messenger molecules	0.6276089130331973	0.9355688510669627	0.3494952184848687	1.0	1.0	4	Q8N8S7,P19174	2
Ethanol oxidation	0.68423975428971	0.9297068512818756	0.3525228861809637	1.0	1.0	3	P30837	1
Pkmts methylate histone lysines	0.5826400623326605	0.927165478631934	0.3538406234854079	1.0	1.0	19	Q9H7B4,O15047,Q86TU7,Q6VMQ6	4
Hdr through single strand annealing ssa	0.5895329956158293	0.9232352511271612	0.3558846221326992	1.0	1.0	21	Q92547,Q9UQ84,Q9BX63,O60921,Q13535	5
Rna polymerase iii transcription initiation from type 1 promoter	0.5482481499069256	0.9166002733882732	0.3593521410657831	1.0	1.0	11	Q12789	1
Nef mediated downregulation of mhc class i complex cell surface expression	0.6026416179984989	0.9139225228439436	0.3607575579568129	1.0	1.0	5	P56377	1
Homologous dna pairing and strand exchange	0.5871218594106894	0.9135087085153336	0.3609750555804403	1.0	1.0	21	Q92547,Q9UQ84,Q9BX63,O60921,Q13535	5
Met receptor recycling	0.6014109768237641	0.9092146558261656	0.3632368295080757	1.0	1.0	5	P46108	1
Role of abl in robo slit signaling	0.6168585525572401	0.8939434153150412	0.3713521671269622	1.0	1.0	4	O94813,Q7Z460	2
Signaling by flt3 fusion proteins	0.5258070463352289	0.8899180716180378	0.3735098795164404	1.0	1.0	7	Q92614,Q01082,Q15643	3
Signal attenuation	0.615342615342614	0.8880960821221319	0.3744890699476393	1.0	1.0	4	P28482,P29353,P62993	3
Negative feedback regulation of mapk pathway	0.6153426153426137	0.8880960821221306	0.37448906994764	1.0	1.0	4	P28482,Q02750,P36507	3
Transcription of e2f targets under negative control by dream complex	0.5947569634079461	0.8838246177107019	0.3767908950590972	1.0	1.0	5	Q5TKA1,P12004,P11388,Q13547	4
Activation of ampk downstream of nmdars	0.5239519348191471	0.8820892880879775	0.3777285244712816	1.0	1.0	7	P54646,P04350	2
Signalling to ras	0.5933864465413421	0.8786093369984873	0.3796131314818862	1.0	1.0	5	P11233	1
Recycling of eif2 gdp	0.5216194659360014	0.8722641769007771	0.3830642756904248	1.0	1.0	7	P20042,Q13144,Q9NR50	3
Signaling by ntrk3 trkc	0.5407400767306481	0.8698385733237799	0.3843886282825548	1.0	1.0	6	Q8WX92,P29353,P62993,P19174	4
Vldlr internalisation and degradation	0.5203495978431096	0.8669238205277141	0.3859837509181938	1.0	1.0	7	O95782,P09496,Q96CW1,Q00610	4
Signaling by ntrk2 trkb	0.5230221752306096	0.8613543473034532	0.3890429116802194	1.0	1.0	8	P29353,P06241,P62993,P19174	4
Hats acetylate histones	0.6040390441648759	0.8587300674967596	0.3904894578633771	1.0	1.0	29	Q9NPF5,O75486,Q9H9T3,Q9UPT9,Q92794,Q8NEM7	6
Sema4d induced cell migration and growth cone collapse	0.5175706766420107	0.8552593779470061	0.3924075707447332	1.0	1.0	7	P35579,O75116	2
Mecp2 regulates transcription of neuronal ligands	0.6623908296943296	0.8456509160958765	0.3977475125624736	1.0	1.0	3	Q96ST3,P51608	2
Role of lat2 ntal lab on calcium mobilization	0.5841722289878103	0.8436830111156535	0.3988465634485076	1.0	1.0	5	P29353,O00459,P06241	3
Downstream signaling of activated fgfr1	0.5833716855799931	0.8406603998532411	0.4005382112089952	1.0	1.0	5	P29353,P62993,P19174	3
Downstream signaling of activated fgfr4	0.5833716855799931	0.8406603998532411	0.4005382112089952	1.0	1.0	5	P29353,P62993,P19174	3
Downstream signaling of activated fgfr3	0.5833716855799931	0.8406603998532411	0.4005382112089952	1.0	1.0	5	P29353,P62993,P19174	3
Downstream signaling of activated fgfr2	0.5833716855799931	0.8406603998532411	0.4005382112089952	1.0	1.0	5	P29353,P62993,P19174	3
Crmps in sema3a signaling	0.5179236654233812	0.8400909706105111	0.4008573823744932	1.0	1.0	8	Q14195,P49841,P06241,Q16555	4
Hdms demethylate histones	0.5254865382276861	0.8385911791171242	0.4016987622665739	1.0	1.0	10	O60341,Q9Y2K7,P41229,Q7LBC6,Q8IUF8	5
Translesion synthesis by polh	0.5365079565122348	0.8353709491122744	0.403508881384649	1.0	1.0	13	Q8TAT6,P35251,P41440,P35244,P12004,P15927,P40938	7
Tie2 signaling	0.5816085036680987	0.8340101740483774	0.404275250688511	1.0	1.0	5	P29353,O00459,P62993	3
Wnt5a dependent internalization of fzd2 fzd5 and ror2	0.516007289641456	0.8321270612860209	0.405337228546839	1.0	1.0	8	O95782,P09496,Q96CW1,Q00610	4
Type i hemidesmosome assembly	0.8316507503410653	0.8240475787501379	0.409912524178889	1.0	1.0	2	Q15149	1
Assembly of collagen fibrils and other multimeric structures	0.8316507503410653	0.8240475787501379	0.409912524178889	1.0	1.0	2	Q15149	1
Traf3 dependent irf activation pathway	0.656386462882103	0.82278065310767	0.4106327405723968	1.0	1.0	3	Q9UHD2,Q14258	2
Synthesis of pips at the early endosome membrane	0.5271855135935674	0.8146392891751337	0.415278814069236	1.0	1.0	6	Q08AM6	1
Oncogene induced senescence	0.5066112585846082	0.8095753185961932	0.4181842981747041	1.0	1.0	7	P28482,P42771,Q00534,P11802	4
Vitamin b2 riboflavin metabolism	0.8272851296043364	0.8083165117204885	0.4189083996233416	1.0	1.0	2	Q969G6	1
Regulation of bach1 activity	0.5940988020104621	0.8068339699769176	0.4197621450197872	1.0	1.0	4	Q9BX63	1
Mapk3 erk1 activation	0.5940485940485987	0.8066435752353587	0.4198718609340286	1.0	1.0	4	P06493,P27361,Q02750	3
Antigen activates b cell receptor bcr leading to generation of second messengers	0.5728913164264089	0.8012802064264126	0.4229694470915563	1.0	1.0	5	P06241,P62993,Q13586	3
Sumoylation of dna methylation proteins	0.5682317903229317	0.7838933812324096	0.433102673803867	1.0	1.0	5	Q9HC52	1
Rhobtb3 atpase cycle	0.5621779170281551	0.761425070929492	0.4464032175308285	1.0	1.0	5	Q15345,Q13618,P51151	3
Signaling by fgfr1	0.5002532069799298	0.7515422078801911	0.4523264090428944	1.0	1.0	9	P28482,P27361,P62993,P29353,P19174	5
Signaling by fgfr3	0.5002532069799298	0.7515422078801911	0.4523264090428944	1.0	1.0	9	P28482,P27361,P62993,P29353,P19174	5
Signaling by fgfr4	0.5002532069799298	0.7515422078801911	0.4523264090428944	1.0	1.0	9	P28482,P27361,P62993,P29353,P19174	5
Notch3 intracellular domain regulates transcription	0.5793246547686854	0.7512003414696018	0.4525320947474087	1.0	1.0	4	Q13573,Q15398	2
Dissolution of fibrin clot	0.6365608869811439	0.7481185684993251	0.4543886428336738	1.0	1.0	3	P35237	1
Assembly of the hiv virion	0.8095497953615294	0.7451232471960454	0.4561972166675412	1.0	1.0	2	Q99816	1
G2 m dna replication checkpoint	0.6356441048035002	0.7447010352751235	0.4564524731785893	1.0	1.0	3	P06493,P14635	2
Signaling by erbb2 ecd mutants	0.4901627396387039	0.7420979030686897	0.4580280202366338	1.0	1.0	7	P29353,P62993,P19174	3
Signaling by erbb2 in cancer	0.4901627396387039	0.7420979030686897	0.4580280202366338	1.0	1.0	7	P29353,P62993,P19174	3
Rho gtpases activate rocks	0.5052834996199125	0.7407597263660466	0.4588391382560364	1.0	1.0	11	P35579,O75116,O14974	3
Sumoylation of transcription cofactors	0.5260964732856956	0.732666886824739	0.4637616248837188	1.0	1.0	17	O75928,Q9UER7,Q14781,Q9HC52	4
Advanced glycosylation endproduct receptor signaling	0.4913013034615052	0.7310509143731451	0.4647480545860893	1.0	1.0	8	P52907	1
Rho gtpases activate paks	0.506635320012346	0.7309007264053968	0.4648397922890102	1.0	1.0	12	P35579,Q13177,Q14247,P60953,O14974	5
Synthesis of pips at the golgi membrane	0.4951062728419606	0.7308426796502786	0.4648752510632512	1.0	1.0	9	Q9UBF8,Q01968,Q08AM6	3
Neurexins and neuroligins	0.4900245968844053	0.7259178800277388	0.4678891146669102	1.0	1.0	8	Q15334,Q96HC4,O43491,O14936,Q14168,P11171,Q9UJU6	7
Rna polymerase i transcription termination	0.5041779057075895	0.7211969785646877	0.4707883304982807	1.0	1.0	12	P17480	1
Fceri mediated mapk activation	0.4996299423323267	0.7183115688997418	0.4725651984931285	1.0	1.0	11	P28482,P62993,Q13177,P29353,O14733,P19174	6
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	0.4996215990111604	0.7182785830854211	0.4725855328586834	1.0	1.0	11	P56377,Q9BXS5	2
Cd28 dependent vav1 pathway	0.5009560229445421	0.7101104509072652	0.4776356459861197	1.0	1.0	6	Q16512,P62993,Q13177,P06241,P60953	5
Carboxyterminal post translational modifications of tubulin	0.4998911759440144	0.7059419932888183	0.4802242113596811	1.0	1.0	6	Q14166,P04350,Q9BUF5	3
Amyloid fiber formation	0.4806245519725145	0.7036652506574693	0.4816412655697011	1.0	1.0	7	Q9Y287	1
Metabolic disorders of biological oxidation enzymes	0.5457156681894205	0.701097634828954	0.4832420862737581	1.0	1.0	5	P48637,P22570	2
Rna polymerase iii transcription	0.4962350352289345	0.6900895028810776	0.4901379040082447	1.0	1.0	12	Q12789	1
Epha mediated growth cone collapse	0.4913808006873761	0.6859136552268761	0.4927675587139259	1.0	1.0	11	Q8N5V2,P35579,O75116	3
Carnitine metabolism	0.4942162861173064	0.6838389535732148	0.4940768659081458	1.0	1.0	6	P54646,O43772	2
Signaling by fgfr4 in disease	0.6188270086068942	0.6826395839310689	0.4948346148092759	1.0	1.0	3	P19174	1
Sema3a plexin repulsion signaling by inhibiting integrin adhesion	0.4933228998858584	0.6803769765372133	0.4962657953082434	1.0	1.0	6	O94887,Q9Y490	2
Shc mediated cascade fgfr4	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Activated ntrk3 signals through ras	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Activated ntrk2 signals through ras	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Shc1 events in egfr signaling	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Shc mediated cascade fgfr1	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Shc1 events in erbb4 signaling	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Shc mediated cascade fgfr3	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Shc related events triggered by igf1r	0.6174099716601475	0.6774683264592215	0.4981088595897243	1.0	1.0	3	P29353	1
Sensory processing of sound by outer hair cells of the cochlea	0.4959167704896826	0.6742861103023491	0.5001294328628836	1.0	1.0	13	P35579,P15311,Q13813,Q14651,Q12792,O14936,Q01082,P26038,P35241,O00159	10
Signaling by kit in disease	0.4713157810487287	0.6667211886496657	0.5049502418494738	1.0	1.0	7	O00459,P06241,P42224	3
Signaling by egfr in cancer	0.4687859640269213	0.656785120399837	0.5113190930659879	1.0	1.0	7	P29353,P07900,P62993,P19174	4
Constitutive signaling by ligand responsive egfr cancer variants	0.4687859640269213	0.656785120399837	0.5113190930659879	1.0	1.0	7	P29353,P07900,P62993,P19174	4
Constitutive signaling by egfrviii	0.4687859640269211	0.6567851203998363	0.5113190930659883	1.0	1.0	7	P29353,P07900,P62993,P19174	4
Inactivation of cdc42 and rac1	0.6105280296006727	0.6524933628355304	0.5140829531344029	1.0	1.0	3	O94813	1
Prc2 methylates histones and dna	0.4859203033489675	0.6518853835283434	0.514475114733099	1.0	1.0	6	Q09028,Q15910,P26358,Q15022	4
Golgi cisternae pericentriolar stack reorganization	0.4822557223422806	0.6506102948997441	0.5152980830493852	1.0	1.0	11	P28482,P53350,Q08379,P14635,P06493,Q9H8Y8,O60763	7
Tak1 activates nfkb by phosphorylation and activation of ikks complex	0.4705919221140235	0.64908949361365	0.5162805323952027	1.0	1.0	8	O15111,P09429,O43318,P61088	4
Inlb mediated entry of listeria monocytogenes into host cell	0.4663520507333483	0.6472698871558878	0.5174572870507346	1.0	1.0	7	O75886,Q9NWH9,O14964,P62993	4
Irak2 mediated activation of tak1 complex	0.7803547066848586	0.6440008367231302	0.519574891414408	1.0	1.0	2	O43318	1
Alpha protein kinase 1 signaling pathway	0.7803547066848586	0.6440008367231302	0.519574891414408	1.0	1.0	2	O43318	1
Ticam1 traf6 dependent induction of tak1 complex	0.7803547066848586	0.6440008367231302	0.519574891414408	1.0	1.0	2	O43318	1
Transcriptional regulation by e2f6	0.4832636744934053	0.6402052606717853	0.5220391631540036	1.0	1.0	12	O00311,P45973,Q9H9B1,Q15910,O14757	5
Met activates rap1 and rac1	0.4825971196028252	0.6392124034448329	0.5226847642421191	1.0	1.0	6	P46108,Q96N67,Q9NWH9	3
Cell junction organization	0.5090310394025083	0.626558346813749	0.5309487792254171	1.0	1.0	20	P14923,Q8TEW0,Q14315,Q03001,P55196,P35221,P12814,Q96AC1,Q15149,Q9BY67	10
Vitamin b5 pantothenate metabolism	0.4792494918330941	0.6265234658774168	0.5309716502849788	1.0	1.0	6	Q96CD2	1
Ercc6 csb and ehmt2 g9a positively regulate rrna expression	0.486156476460839	0.6232072047816097	0.5331483677602706	1.0	1.0	14	O95983,Q96KQ7,Q12873,P62805,Q13185,Q86YP4,Q92769,Q14839,Q09028,Q8WXI9,Q13547	11
Displacement of dna glycosylase by apex1	0.6022707154306651	0.622849399684113	0.5333834922057357	1.0	1.0	3	P27695	1
Signalling to erks	0.4821575509904177	0.6220485058039588	0.5339099734648349	1.0	1.0	13	P28482,Q02750,P46108,P62993,P11233,P29353,P36507	7
Fceri mediated ca 2 mobilization	0.4779732314642997	0.6217068648753212	0.5341346367982855	1.0	1.0	6	P29353,P62993,P19174	3
Hdr through homologous recombination hrr	0.5434537355093528	0.6213139498399913	0.5343930770269785	1.0	1.0	30	P35251,Q92547,Q9UQ84,P41440,Q9BX63,O60921,Q13535	7
Metabolism of rna	0.2495802313281225	0.6151456583747872	0.5384585313940298	1.0	1.0	486	P62847,Q969T7,Q6UN15,Q15459,Q05519,P61247,P08708,P35637,P52298,P67809,Q9BVL2,P51665,P46087,P46782,P28070,P49721,Q9UBP6,Q9H074,P23588,P24928,O43395,O75533,P52756,Q86TB9,Q9Y4Z0,P78346,Q96C86,Q92620,Q8TEQ6,Q96FX7,Q9NY93,Q9P2I0,Q86XP3,Q96QD9,O60306,O75832,Q7Z4G4,Q8WVM0,P51991,Q13868,P84098,P62314,Q9BVI4,Q9Y2L1,Q9BVJ6,Q7L014,Q8IYB3,O60832,Q9H2H8,Q969Y2,Q08170,P84103,Q9BUJ2,Q92917,P78316,P62910,P62829,Q52LJ0,Q13895,Q9C0J8,Q9H0S4,O75175,Q99436,Q96BP3,Q9HCS7,Q96PZ0,Q9Y3I0,O75152,P18077,Q92530,Q2NL82,Q9Y5S9,P04792,Q9UNQ2,P11940,Q9UBB9,Q9NV31,Q9H974,P19338,P39687,P62244,Q04637,Q13573,Q8WUA2,Q07020,Q8IZH2,Q99459,Q14692,Q15287,Q9Y3Y2,Q9H6R4,O00267,Q9Y3U8,Q16629,Q14103,O75400,Q9HCG8,P09661,O43290,O43709,P62841,P62899,P35268,Q99848,Q96GA3,Q8IX12,P25787,P46779,P19447,Q92499,Q9Y4W2,P51003,P26196,O60231,O15504,P35658,P42766,P62851,Q14690,Q13601,P62917,P62913,P62263,Q8TEM1,Q6PGP7,Q8IY37,Q9Y6V7,Q9Y2R4,P20618,Q9BZI7,Q9GZS3,Q9C0C2,Q9BZJ0,P40429,P18124,Q9UQ35,P39023,P83881,P12270,P13984,Q15008,P63173	142
Nucleotide salvage	0.4610095633777525	0.6122071614084295	0.5404007040452343	1.0	1.0	8	P00491,Q08623,P55263,Q9BZX2	4
Polymerase switching on the c strand of the telomere	0.489872252888793	0.6098129064745857	0.5419857508821682	1.0	1.0	16	P49642,P41440,Q8WVB6	3
Mitochondrial iron sulfur cluster biogenesis	0.5403920853682459	0.6092257550376361	0.5423748112435323	1.0	1.0	4	Q9H1K1,P22570	2
Nectin necl trans heterodimerization	0.7699863574351575	0.6091030212688803	0.5424561551193472	1.0	1.0	2	Q9BY67	1
Alk mutants bind tkis	0.4550927608793574	0.60384846899232	0.5459443916154809	1.0	1.0	7	O00291,Q9NR09,Q9HC35,Q00610,O43815	5
Gab1 signalosome	0.5938864628821039	0.5931367368634706	0.5530896464902304	1.0	1.0	3	P41240,P62993	2
Met activates ptpn11	0.5938864628821039	0.5931367368634706	0.5530896464902304	1.0	1.0	3	Q9NWH9,P62993	2
Mapk1 erk2 activation	0.5938864628821039	0.5931367368634706	0.5530896464902304	1.0	1.0	3	P28482,P36507	2
Molybdenum cofactor biosynthesis	0.5937195339466301	0.5925493272833763	0.5534827997601535	1.0	1.0	3	Q9NQX3	1
Apobec3g mediated resistance to hiv 1 infection	0.5929886595886409	0.5899794059945636	0.5552044563557137	1.0	1.0	3	P17096	1
Negative regulation of mapk pathway	0.482744156417096	0.5838758999581298	0.559303808555148	1.0	1.0	16	P10398,P28482,Q14738,Q02750,Q13362,Q16537,P36507,P53041	8
Mrna capping	0.482067326340489	0.5814354646778302	0.5609470011905806	1.0	1.0	16	P19447,P52298,P13984,O00267	4
Flt3 signaling in disease	0.4563062189291593	0.5805562175410646	0.5615395875147644	1.0	1.0	9	Q15643,Q92614,P62993,Q06124,Q01082,Q9UBW7	6
Traf6 mediated irf7 activation	0.5320788019199519	0.5799844405252905	0.5619251105300909	1.0	1.0	4	Q9UHD2,Q14258	2
Purine salvage	0.5095500846852707	0.5734482772865729	0.5663412103488366	1.0	1.0	5	Q16854,P00491,P55263	3
Downregulation of erbb4 signaling	0.7587994542974101	0.5721275405472463	0.5672355723354552	1.0	1.0	2	P46934	1
Constitutive signaling by overexpressed erbb2	0.4644431546212535	0.5714002886484962	0.5677283334755283	1.0	1.0	6	Q96RT1,P29353,P62993	3
Oas antiviral response	0.5870633187772998	0.5692651662047398	0.5691762024533624	1.0	1.0	3	P61221,P21333	2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants	0.5073428127784958	0.5659164670808446	0.5714505668158689	1.0	1.0	5	O00459,P62993,P42224	3
G1 s specific transcription	0.4627836260048396	0.5641027332209152	0.572684218051466	1.0	1.0	12	P04818	1
Signaling by met	0.5044236885750805	0.5597083926750285	0.5756783568367814	1.0	1.0	24	Q96S59,P07942	2
Pecam1 interactions	0.5242706517380856	0.5529278057658902	0.5803128464343783	1.0	1.0	4	P06241,P19174	2
Stat3 nuclear events downstream of alk signaling	0.5233415233415303	0.5497358631080177	0.5825005549828366	1.0	1.0	4	Q92769,Q96ST3,Q13547	3
Collagen formation	0.4593758928344525	0.5389446997822281	0.5899250127248115	1.0	1.0	13	Q32P28,Q15149,P13674,O15460	4
Wnt5a dependent internalization of fzd4	0.4519976235326993	0.5382647742982584	0.5903942667775541	1.0	1.0	11	O14641,P32121	2
Signaling by pdgf	0.4444945721424659	0.537242777052632	0.5910999264920307	1.0	1.0	9	P46108,O00459,P62993,P42224,P19174	5
Downstream signal transduction	0.4444945721424659	0.537242777052632	0.5910999264920307	1.0	1.0	9	P46108,O00459,P62993,P42224,P19174	5
Zbp1 dai mediated induction of type i ifns	0.454708184607078	0.5361281551233033	0.5918699827044338	1.0	1.0	6	Q9UHD2	1
Thrombin signalling through proteinase activated receptors pars	0.4368739258511385	0.5358949168814165	0.5920311777171188	1.0	1.0	7	P32121	1
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10	0.4978197385325869	0.5338141449390005	0.5934701264278472	1.0	1.0	5	O15111,Q14790,Q14258	3
Integrin signaling	0.4515933247308681	0.5250189952757013	0.5995699861233665	1.0	1.0	6	P46108,P29353,P41240,Q9Y490	4
Platelet aggregation plug formation	0.4515933247308681	0.5250189952757013	0.5995699861233665	1.0	1.0	6	P46108,P29353,P41240,Q9Y490	4
Signaling by csf3 g csf	0.4371631076511698	0.5238463113893028	0.6003854393970329	1.0	1.0	8	P29353,Q93034,P62993,P42224	4
E3 ubiquitin ligases ubiquitinate target proteins	0.4689208596940029	0.522605916735251	0.6012485222523372	1.0	1.0	17	Q5VTR2,P50542	2
Sensory processing of sound	0.4722357038139447	0.5218883722937155	0.601748054660362	1.0	1.0	18	P35579,P15311,P52907,P56545,Q01082,P26038,P35241	7
Dna replication initiation	0.4320328551205752	0.5183714669270377	0.6041991184998579	1.0	1.0	7	P49642	1
Dna damage telomere stress induced senescence	0.4675303539800689	0.5178446876669025	0.6045666364820488	1.0	1.0	17	Q9Y6J0	1
Dual incision in gg ner	0.4951426401168026	0.5168619999035674	0.6052524959914289	1.0	1.0	25	Q86WJ1,P35251,Q9UGN5,P19447,P41440,Q13620,Q07864,P35244,P09874,P12004,Q92889,P28340,P15927,P40938	14
Cyclin d associated events in g1	0.4414584140435268	0.513574899300581	0.6075492324673246	1.0	1.0	10	P63151,Q13309,P11802,P42771,Q00534	5
Prolonged erk activation events	0.4335598902982127	0.5109702101471756	0.6093719165672922	1.0	1.0	8	P28482,Q02750,P36507,P46108	4
Rho gtpases activate ktn1	0.4366787544775786	0.5093277241134443	0.6105225280764661	1.0	1.0	9	Q9H0B6,P84095,Q07866,P60953,Q9NSK0	5
Regulation of signaling by cbl	0.4291933160980468	0.5082052865664115	0.6113093838028707	1.0	1.0	7	P46108,O00459,P06241	3
Cell extracellular matrix interactions	0.4272932419752713	0.5014501987088835	0.6160543185657235	1.0	1.0	7	Q14315,P12814,Q96AC1,P21333	4
Diseases of immune system	0.5082242893892454	0.4986860577562503	0.6180005681735576	1.0	1.0	4	P09429	1
G alpha 12 13 signalling events	0.4429635576177189	0.494097522270752	0.6212373076493147	1.0	1.0	12	Q8N5V2,O75116,Q13464	3
Kinesins	0.4808050419901368	0.4925387513668999	0.6223385344230967	1.0	1.0	23	Q9NS87,Q9BUF5,Q9H0B6,O95239,O95235,O00139,Q96Q89,P52732,Q07866,Q9BVA1,P04350,O60333,Q9Y496,Q9NSK0,Q9BW19	15
Mtorc1 mediated signalling	0.4424238635160019	0.4922474263374979	0.6225444410402221	1.0	1.0	12	P23588,Q15382	2
Peroxisomal protein import	0.4907355197553522	0.4914567965818989	0.6231034017391894	1.0	1.0	26	O75874,P50542	2
Sumo is conjugated to e1 uba2 sae1	0.5641273535151339	0.4912858809131966	0.6232242645393788	1.0	1.0	3	Q9UBT2	1
Sumo is transferred from e1 to e2 ube2i ubc9	0.5641273535151339	0.4912858809131966	0.6232242645393788	1.0	1.0	3	Q9UBT2	1
Mastl facilitates mitotic progression	0.4847338580116179	0.4908169217708327	0.6235559405262379	1.0	1.0	5	P14635	1
Signaling by flt3 itd and tkd mutants	0.5615018262917255	0.4826023260922193	0.6293781271839194	1.0	1.0	3	P62993	1
Frs mediated fgfr1 signaling	0.5615018262917255	0.4826023260922193	0.6293781271839194	1.0	1.0	3	P62993	1
Frs mediated fgfr2 signaling	0.5615018262917255	0.4826023260922193	0.6293781271839194	1.0	1.0	3	P62993	1
Activated ntrk2 signals through frs2 and frs3	0.5615018262917255	0.4826023260922193	0.6293781271839194	1.0	1.0	3	P62993	1
Frs mediated fgfr3 signaling	0.5615018262917255	0.4826023260922193	0.6293781271839194	1.0	1.0	3	P62993	1
Frs mediated fgfr4 signaling	0.5615018262917255	0.4826023260922193	0.6293781271839194	1.0	1.0	3	P62993	1
Glycogen metabolism	0.4325346672777613	0.482533668384401	0.6294268869795938	1.0	1.0	10	P13807,P35573,Q93100,Q96G03,P46976	5
Cytosolic sensors of pathogen associated dna	0.4693242687936907	0.4776088594109369	0.6329286240360945	1.0	1.0	21	Q9UHD2,O15111,P19474,Q9BUI4	4
Ret signaling	0.4201894554348555	0.4765441951494261	0.6336867294052864	1.0	1.0	7	O00459,P62993,Q9NR12,P29353,P19174	5
Activation of rac1	0.5006825006825135	0.4738821212000688	0.6355839693040082	1.0	1.0	4	Q16512,Q13177,O94813	3
Interleukin 6 family signaling	0.4998634998634997	0.4712168184386393	0.6374859096017871	1.0	1.0	4	Q06124,P40763,P42224	3
Interleukin 6 signaling	0.4998634998634997	0.4712168184386393	0.6374859096017871	1.0	1.0	4	Q06124,P40763,P42224	3
Transport of connexons to the plasma membrane	0.4784973108059288	0.4708153254931707	0.6377726193962019	1.0	1.0	5	P04350,Q9BUF5	2
Gap junction assembly	0.4784973108059288	0.4708153254931707	0.6377726193962019	1.0	1.0	5	P04350,Q9BUF5	2
Infectious disease	0.2561162844717415	0.469443980385623	0.638752318030646	1.0	1.0	367	Q99720,P62847,Q96F07,Q13177,P61247,O95782,P56377,P08708,Q9UER7,P52298,Q9BVL2,P51665,P46782,Q63HN8,P17096,P28070,Q96SB4,P49721,Q15910,P24928,P19174,Q9UQB8,P49841,Q02750,Q13464,P63218,Q93034,Q99816,Q9UHD2,O14733,O75832,P48729,P29083,O75475,P84098,Q9HD42,Q8WXI9,Q9H9H4,P46108,Q9Y6G9,P04350,O75116,P00558,Q16881,Q15185,Q00403,P62910,P62829,P23193,Q99436,P18077,P78362,Q92530,Q14839,P46060,P50750,P62244,Q96FJ2,Q8WUW1,Q07020,O00267,Q9Y3U8,Q14185,Q9H3P2,Q9HBM6,P35579,P62841,Q12873,P62899,P52294,Q86YP4,P35268,P18858,P25787,P46779,P19447,Q9Y5B9,Q14241,Q16706,O15504,P35658,P42766,P62851,Q00610,P62917,P62913,P62263,Q9BXS5,Q9NWH9,Q8TEM1,O14641,Q9BRG1,P55199,P20618,Q9NZQ3,P40429,P18124,O95983,O60341,P39023,P83881,P09874,P12270,P13984,Q13618,Q13263,Q15008,P63173,P62424,P61160,P60953	111
Pcna dependent long patch base excision repair	0.4595591754338746	0.4682405564413546	0.6396125723999042	1.0	1.0	19	P18858,P35251,Q07864,P41440,P35244,P12004,P28340,P15927,P40938,P27695	10
Ctla4 inhibitory signaling	0.4236926223303676	0.4643834944078829	0.6423730134623324	1.0	1.0	9	Q16537,Q14738,Q13362	3
Negative regulation of fgfr1 signaling	0.4338283695088151	0.4634475612411381	0.6430435940467847	1.0	1.0	6	P28482,Q06124,P27361,P62993	4
Negative regulation of fgfr4 signaling	0.4338283695088151	0.4634475612411381	0.6430435940467847	1.0	1.0	6	P28482,Q06124,P27361,P62993	4
Negative regulation of fgfr3 signaling	0.4338283695088151	0.4634475612411381	0.6430435940467847	1.0	1.0	6	P28482,Q06124,P27361,P62993	4
Negative regulation of fgfr2 signaling	0.4338283695088151	0.4634475612411381	0.6430435940467847	1.0	1.0	6	P28482,Q06124,P27361,P62993	4
Spry regulation of fgf signaling	0.4338283695088151	0.4634475612411381	0.6430435940467847	1.0	1.0	6	P28482,Q06124,P27361,P62993	4
Metabolism of folate and pterines	0.4230103281808921	0.4620745854511875	0.6440278347190531	1.0	1.0	9	P41440,P34897,P34896	3
Repression of wnt target genes	0.4756993467675349	0.4619505400945439	0.6441167894963984	1.0	1.0	5	Q04727	1
Potential therapeutics for sars	0.5253819586239111	0.4554916348866773	0.6487555842810282	1.0	1.0	40	Q99720,Q12873,Q9UHD2,Q14839,O75116	5
Recognition of dna damage by pcna containing replication complex	0.4506508590308881	0.4506593890501716	0.6522350560803514	1.0	1.0	18	P35251,Q07864,P41440,Q13620,P35244,P12004,P28340,P15927,P40938	9
Termination of translesion dna synthesis	0.4502396839748163	0.4493521708682879	0.653177628375976	1.0	1.0	18	P35251,Q07864,P41440,P35244,Q14258,P12004,P28340,P15927,P40938	9
Processing of dna double strand break ends	0.503483527578091	0.4486287978528949	0.6536994560561515	1.0	1.0	34	Q92547,Q9UQ84,Q9BX63,P61088,O60921,Q13535	6
Rho gtpases activate iqgaps	0.4258407002676233	0.448261597126859	0.653964412574616	1.0	1.0	11	P46940,P35221,P04350,Q13576,P60953	5
Synthesis of active ubiquitin roles of e1 and e2 enzymes	0.4256464893119974	0.4476219735406668	0.6544260420504546	1.0	1.0	11	Q93008,P22314,Q16763,P45974,Q93009,P61086,P68036,P49427,P60604	9
Rna polymerase ii transcription	0.2766739839074276	0.4471515902418269	0.6547656116953158	1.0	1.0	348	Q9UQ84,Q6UN15,Q68E01,O60244,Q05519,Q9UER7,P52298,P51665,P46087,Q13362,P28070,Q15382,P49721,Q92925,Q9NP77,Q15910,Q92794,P24928,Q13535,P49841,Q93074,Q92620,Q9HC52,Q9P2I0,P51608,Q9BX63,Q96QD9,O75832,P42771,P29083,Q07157,Q92547,O15047,Q8N201,Q8WXI9,Q15648,Q5VT52,Q6PD62,Q9NYV4,Q8IYB3,P19784,P51530,Q16881,Q00403,Q13309,Q08170,P84103,Q9C0J8,Q9H1A4,P54646,P23193,P14635,O75175,Q99436,Q96HW7,O75152,Q92530,Q14839,O14965,Q9Y5S9,P50750,P15954,Q13573,Q9UBL3,Q15287,Q9Y3Y2,O00267,Q7KZ85,P45973,P67870,Q9H9B1,Q9H3P2,Q16629,Q9HBM6,O14757,Q12873,Q86YP4,P51532,P38398,Q96PK6,Q14781,Q96J02,O60921,O14497,Q9UJX6,P25787,Q9NVM9,Q9UHA4,P19447,Q9UPN9,P51003,Q16763,Q9Y5B9,Q14241,Q13472,Q9NWH9,O00311,P55199,P20618,Q9BZI7,Q92696,Q8WYQ5,P09874,P13984	104
Tnfr1 induced nfkappab signaling pathway	0.4097997123530937	0.4411616572151874	0.6590959692957425	1.0	1.0	7	O15111,O43318	2
The role of nef in hiv 1 replication and disease pathogenesis	0.4336037654837865	0.4398887111328463	0.6600177124561459	1.0	1.0	14	O95782,P56377,Q13177,P06241,Q9BXS5,Q10567	6
Runx1 interacts with co factors whose precise effect on runx1 targets is not known	0.4429910163688866	0.4371905881230334	0.6619731348726554	1.0	1.0	17	O14497,Q86U86,Q9HC52,P67870,Q92925,P51532,Q68CP9,P19784,Q14781	9
P130cas linkage to mapk signaling for integrins	0.7154160982264347	0.4364707655307928	0.6624952055060578	1.0	1.0	2	P46108	1
Base excision repair ap site formation	0.4661387220098281	0.4321912114259854	0.665602446360906	1.0	1.0	5	P78549,P29372,P62805,Q9NYB0	4
Rna polymerase i promoter escape	0.4345025421086532	0.4318687686761508	0.6658367948526098	1.0	1.0	15	P17480	1
Polymerase switching	0.4297258197097626	0.427529631821019	0.6689936071549876	1.0	1.0	14	P49642,P41440	2
Cell cycle	0.2910764637082592	0.4262357080018882	0.6699361004302651	1.0	1.0	330	Q9UQ84,O43683,Q9H3R5,Q86Y07,Q9Y248,P04818,O15078,O60763,Q9UER7,P51665,Q9BVL2,Q96RT8,Q5TKA1,Q7L590,Q13362,P28070,P49721,P41440,Q7Z460,P24928,Q13535,O43264,Q6KC79,P49454,P49841,Q07864,Q8WVB6,Q08379,Q8N3U4,Q9H900,Q9Y6D9,Q9BX63,O75832,P42771,Q14683,Q92547,P49642,P61088,Q15154,Q9Y6G9,P23258,P19784,P04350,O60832,Q8NF91,P51530,Q14738,Q9Y6X3,Q13309,Q9H1A4,P14635,Q99436,Q9NTI5,Q9Y266,Q92530,O14965,Q96FJ2,Q96EA4,Q99986,O14974,P67870,Q14980,Q96BD8,O60921,P18858,P25787,P35251,O15504,P35658,P53350,Q13472,Q14008,Q96T23,O00311,P50748,P20618,Q9NTJ3,P12270	78
Meiotic synapsis	0.4375621897386755	0.4202740734157421	0.6742852476455121	1.0	1.0	17	Q14683,Q8WXH0,P38398,Q13535,O94901,Q9UQE7,Q8N3U4,Q8NF91,O60216	9
Nef and signal transduction	0.542032006801848	0.4199515406040064	0.6745208548737316	1.0	1.0	3	Q13177	1
Dcc mediated attractive signaling	0.4588190783222798	0.4099892070970603	0.6818138648399279	1.0	1.0	5	Q14185,P60953	2
Nef mediated cd8 down regulation	0.4162821577053177	0.4059395467806208	0.684787019655313	1.0	1.0	6	P63010,O95782,Q96CW1	3
Nef mediated cd4 down regulation	0.4162821577053177	0.4059395467806208	0.684787019655313	1.0	1.0	6	P63010,O95782,Q96CW1	3
Rna polymerase i transcription initiation	0.4523660667490924	0.4047566363447438	0.6856564065224338	1.0	1.0	23	Q86YP4,P17480,Q12873,Q14839	4
Rhobtb1 gtpase cycle	0.4421152058585885	0.4037376063948994	0.6864056823432265	1.0	1.0	20	Q5VTR2,O75116,Q8IYB3	3
Transcriptional regulation of white adipocyte differentiation	0.4282609829294659	0.4021115888149055	0.6876019043494921	1.0	1.0	16	Q93074,O60244,Q15648	3
Regulation of runx1 expression and activity	0.5360262008733716	0.401287758048885	0.6882082756087939	1.0	1.0	3	Q06124,Q00534	2
Signaling by erythropoietin	0.4130444257605198	0.3957218138754703	0.692310261263225	1.0	1.0	6	P19174	1
Downregulation of tgf beta receptor signaling	0.4128139046416341	0.3949992344760336	0.6928434529336507	1.0	1.0	6	P62136	1
Insulin receptor signalling cascade	0.4023880653993955	0.394974640305547	0.6928616036630963	1.0	1.0	9	P28482,Q99570,P27361,O00459,P62993,P29353	6
Signaling by fgfr2 in disease	0.418814418948477	0.3937590781006255	0.6937589195455311	1.0	1.0	14	P52298,P24928,P13984	3
Netrin 1 signaling	0.4116734104570159	0.3924172851914083	0.6947499164545172	1.0	1.0	12	Q14185,P19174,P15311,P60953,O94813	5
Oxidative stress induced senescence	0.4308537171667958	0.3900228704970526	0.696519635291639	1.0	1.0	18	P28482,P27361,Q9HC52,Q15910,O14733,P11802,Q14781,P42771,Q00534,Q15022	10
Early phase of hiv life cycle	0.400586039867045	0.3893715191717066	0.6970013373792372	1.0	1.0	9	P18858,P17096,O75475	3
Glycogen breakdown glycogenolysis	0.3933695763484626	0.3879593093191972	0.6980461462015037	1.0	1.0	7	Q96G03,P46976,Q93100,P35573	4
Negative regulation of the pi3k akt network	0.4282156321014588	0.3823135551050615	0.702228801470504	1.0	1.0	18	P28482,Q14738,P27361,P84095,O00459,P62993,Q13362,P06241,Q9NWH9,Q16537,O43815	11
Telomere extension by telomerase	0.4011058174980987	0.3806498690650393	0.7034630718963415	1.0	1.0	10	Q9BUR4,Q9NPE3,Q5H9R7,O60832	4
Signaling by rho gtpases miro gtpases and rhobtb3	0.2155469439370749	0.3804002923788487	0.7036482976190448	1.0	1.0	290	Q07960,O43683,Q13492,Q9H3R5,Q96F07,Q13177,Q5VTR2,Q86Y07,O00308,Q8N5V2,P15924,Q13362,Q9H0B6,P41440,Q13017,P12814,Q7Z460,Q9UQB8,O43264,O15498,P49454,Q13464,Q03001,Q01968,Q9H2G2,Q9H900,Q9NQW6,Q9Y6D9,Q9HD26,Q9P2R3,Q9UDY2,Q9Y2I1,Q02952,Q9Y6G9,Q8IYB3,P35221,P04350,O75116,O00161,Q14738,Q96AC1,Q7Z6E9,Q9P0U3,Q9Y266,P80723,P46060,Q96FJ2,Q8WUW1,P14923,Q15345,Q96EA4,Q53HL2,Q9Y597,O14974,Q14185,Q9UEY8,Q9UNZ2,Q14247,P34897,P35579,P84095,Q96BD8,Q96C19,Q8WYP5,Q9NYL9,Q9NSV4,O60610,O43396,O94887,P46940,P53350,Q16513,Q14008,Q00610,Q96N67,O14641,P50748,Q9NZQ3,Q9H8V3,Q96T58,Q16537,Q9NSK0,P31948,O60341,Q9Y4F1,O60245,P60763,O00139,P41240,Q13618,Q01082,P61160,P60953	93
Mrna decay by 5 to 3 exoribonuclease	0.4004815169931802	0.3787548503269597	0.704869917876038	1.0	1.0	10	Q86TB9	1
Rna polymerase ii transcribes snrna genes	0.4774714332362559	0.3762783264311181	0.7067099903576282	1.0	1.0	34	Q9NVM9,Q00403,Q5VT52,Q68E01,P52298,P55199,Q9NP77,Q96HW7,Q8N201,P13984,P24928,P29083,P50750,O00267	14
Translesion synthesis by y family dna polymerases bypasses lesions on dna template	0.4346648041911923	0.3727457040379316	0.7093377169485295	1.0	1.0	21	Q8TAT6,P35251,Q07864,P41440,P35244,Q14258,P12004,P28340,P15927,P40938	10
Developmental biology	0.2639698776578171	0.371331368141538	0.7103907370567868	1.0	1.0	282	P62847,Q14195,Q13177,Q9Y490,Q96S59,O60244,P61247,P07942,Q8N5V2,P15924,O95782,P08708,P52298,P51665,P46782,Q8N8S7,P28070,Q01518,P46777,P38919,P49721,Q14919,Q15910,Q14574,Q7Z460,P24928,P19174,O94813,P49841,Q02750,Q93074,Q13464,O75928,Q13813,P06241,Q13200,Q12955,P62753,P61254,O00459,O75832,P35241,P84098,Q9BUF5,A0MZ66,Q15648,P36507,P28482,P05387,O95239,O15144,P48556,Q9NR12,P35221,P29353,P19784,P04350,O75116,P62750,P62277,P62910,P62829,Q99436,P18077,Q92530,Q9Y5S9,P11940,P62244,P14923,Q6ZW49,Q04637,Q13573,Q07020,Q9UBL3,Q15287,Q9Y3U8,Q14185,O15020,P67870,O60271,P35579,P62841,P62899,P51532,P35268,Q9Y2W1,P15311,P25787,P46779,P26038,O94887,P42766,P62851,Q00610,P62917,P62913,P62263,Q9NWH9,P20618,Q9BZI7,P40429,P18124,P39023,P83881,Q01082,Q15008,P63173,P62424,P61160,P60953,P46939	111
Fanconi anemia pathway	0.3946503842042047	0.3712292653934601	0.7104667773786582	1.0	1.0	9	P35244,Q9NVI1,Q9BXW9,Q92889,P15927,Q13535	6
Butyrate response factor 1 brf1 binds and destabilizes mrna	0.3975771660584195	0.370009702179061	0.7113752613508757	1.0	1.0	10	Q9Y2L1,Q13868,Q8IZH2	3
Scavenging by class f receptors	0.4668304668304782	0.368825400768778	0.7122578703436699	1.0	1.0	4	Q9Y4L1,P07900,Q92598	3
Rho gtpases activate cit	0.3969038777426593	0.3679991685902091	0.7128738541279087	1.0	1.0	10	O14974	1
Interleukin 7 signaling	0.5249739119156036	0.3678247678328822	0.7130038996932955	1.0	1.0	3	P51532	1
Chrebp activates metabolic gene expression	0.4443270481200003	0.3676257968216619	0.7131522767695542	1.0	1.0	5	O00763	1
Pyrimidine salvage	0.5248420338163053	0.3674326400237029	0.7132963284412652	1.0	1.0	3	Q9BZX2	1
Cell cycle mitotic	0.2654795396823333	0.3668083794600058	0.7137619567756526	1.0	1.0	278	P18858,P25787,P35251,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,O14965,Q86Y07,Q9Y248,O75832,P04818,P42771,O15078,O60763,Q96FJ2,Q14683,O15504,P35658,P53350,P51665,Q9BVL2,Q14008,Q96EA4,Q96RT8,P49642,Q7L590,Q5TKA1,Q99986,Q13362,P28070,O14974,P49721,Q15154,O00311,P67870,Q9Y6G9,P41440,P50748,P20618,P23258,P19784,Q7Z460,P04350,P51530,Q9NTJ3,O43264,Q6KC79,Q14738,P49841,P49454,Q9Y6X3,Q13309,Q07864,Q14980,Q08379,Q96BD8,P12270,Q9H1A4,P14635,Q99436,Q8N3U4,Q9NTI5	65
Recognition and association of dna glycosylase with site containing an affected purine	0.4660114660114668	0.366423660367649	0.7140489671683876	1.0	1.0	4	P29372,P62805,Q9NYB0	3
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3	0.4660114660114618	0.3664236603676338	0.7140489671683989	1.0	1.0	4	P62805,Q16512,O60341	3
Signaling by fgfr2 iiia tm	0.3995072496539844	0.3658813477620478	0.7144536151091141	1.0	1.0	11	P52298,P13984	2
Fgfr2 mutant receptor activation	0.3995072496539844	0.3658813477620478	0.7144536151091141	1.0	1.0	11	P52298,P13984	2
Collagen biosynthesis and modifying enzymes	0.3992617969537179	0.3651569861672663	0.7149942246085532	1.0	1.0	11	Q32P28,O15460	2
Interleukin 15 signaling	0.5231986899563413	0.3625608276714138	0.7169329768710186	1.0	1.0	3	P29353,P62993	2
Interleukin 20 family signaling	0.5231986899563402	0.3625608276714109	0.7169329768710209	1.0	1.0	3	Q06124,P42224	2
Map3k8 tpl2 dependent mapk1 3 activation	0.4414878619157996	0.359587106924119	0.7191559267043284	1.0	1.0	5	O15111	1
Dna damage bypass	0.43620809521261	0.3592152251739793	0.7194340876732532	1.0	1.0	23	P35251,P15927,P41440,Q13620,Q07864,P35244,Q14258,P12004,P28340,Q8TAT6,P40938	11
Regulation of tp53 activity through phosphorylation	0.481430071000763	0.3547744211220212	0.7227585924754105	1.0	1.0	38	Q92547,Q9UQ84,P67870,Q9HBM6,P54646,Q9BX63,Q9Y5B9,O60921,Q13535	9
Signaling by egfr	0.4106664181585574	0.3509166538374255	0.7256508770794157	1.0	1.0	16	Q13685,P41240,P62993,Q9Y6I3,P29353,Q06124,O14964,P19174,P60953	9
Lagging strand synthesis	0.4204241828810435	0.3424746822997404	0.7319936939272202	1.0	1.0	20	P18858,P49643,P35251,P51530,P49005,P41440,P35244,P49642,P27694,P12004,P28340,P15927,P40938	13
Ovarian tumor domain proteases	0.3774124081883568	0.3398317277611867	0.733983253054882	1.0	1.0	7	P06493,Q96FW1,Q14258	3
Degradation of the extracellular matrix	0.3896896802413864	0.3375785346395389	0.7356808203994631	1.0	1.0	11	P20810,P07942	2
Mecp2 regulates neuronal receptors and channels	0.3743513797955917	0.3310268905301107	0.7406241738356667	1.0	1.0	7	Q13547,Q96ST3,Q9NWH9,P51608	4
Processive synthesis on the lagging strand	0.3968940195091182	0.3307247883641343	0.7408523765864234	1.0	1.0	14	P18858,P49643,P49005,P35244,P49642,P27694,P12004,P28340,P15927,P51530	10
Amino acids regulate mtorc1	0.3992750587206857	0.3285087102677207	0.7425270595545046	1.0	1.0	15	Q15382	1
Signaling by moderate kinase activity braf mutants	0.4018962247245388	0.3269928891489183	0.7436732634861567	1.0	1.0	16	P10398,P28482,Q02750,P46940,P41240,Q9Y490,P18206,P32121,P36507	9
Costimulation by the cd28 family	0.4050412855794916	0.3269082057694074	0.7437373144881096	1.0	1.0	17	Q14738,O00459,P41240,Q13177,Q13362,P06241,Q16537,P60953	8
Processive synthesis on the c strand of the telomere	0.387933267487689	0.3237960397102096	0.7460924546688803	1.0	1.0	12	P18858,P49005,P35244,P27694,P12004,Q9NYB0,P28340,P15927,P51530	9
Integration of provirus	0.3707231839547812	0.3207758666540207	0.7483802493268081	1.0	1.0	7	P17096,O75475	2
Deadenylation of mrna	0.4041351086138481	0.3163134323783351	0.7517646166192784	1.0	1.0	18	P38919,Q04637,Q9H074,P23588,Q9C0C2,P11940,O75175	7
Telomere c strand lagging strand synthesis	0.4197067863230163	0.316292180494158	0.7517807458060424	1.0	1.0	23	P18858,P35251,P51530,P41440,Q8WVB6,P35244,P49642,P27694,P12004,Q9NYB0,P28340,P15927,P40938	13
Cell cell communication	0.4467410482953636	0.3152049016027079	0.752606084183308	1.0	1.0	32	Q13418,Q8TEW0,P14923,P46940,Q13813,Q14315,Q03001,Q92692,Q9Y5K6,P55196,P35221,P21333,P12814,Q96AC1,Q01082,P06241,Q15149,Q9BY67	18
Translation	0.1507888346892276	0.3130843306802603	0.7542165934022127	1.0	1.0	230	P62847,Q96GC5,P61247,P55884,Q13155,P08708,P49406,P46782,P26640,P54577,P60228,P46777,Q9BYN8,P23588,P49590,O76094,P43897,P20042,O75822,P49588,Q9NR50,Q96GW9,P82930,P62753,P61254,Q96A35,Q13084,Q7Z2W9,P49591,P84098,Q9HD33,P09132,P05387,Q14232,P62750,P62277,Q96E11,P62910,P62829,Q96RP9,Q9Y2Z4,Q9NWU5,Q9UBQ5,P18077,O15372,P11940,P37108,P62244,P56537,P09001,Q15031,Q04637,Q14152,Q07020,P62495,Q5T160,Q9Y3U8,Q9BYC9,Q9Y5N5,O75821,P62841,Q4U2R6,P62899,P35268,O60841,P46779,Q9P0M9,P42766,P62851,Q15046,Q13144,P62917,P62913,P62263,Q8TAE8,O43324,P40429,P18124,Q9P015,Q9Y3D9,P39023,P83881,P61009,P63173,P62424,P82912	86
Nervous system development	0.2848641632108313	0.3108663808924308	0.755902203208555	1.0	1.0	228	P62847,Q14195,Q13177,Q9Y490,Q96S59,P61247,P07942,Q8N5V2,O95782,P08708,P52298,P51665,P46782,Q8N8S7,P28070,Q01518,P46777,P38919,P49721,Q7Z460,P19174,O94813,P49841,Q02750,Q13464,Q13813,P06241,Q13200,Q12955,P62753,P61254,O00459,O75832,P35241,P84098,Q9BUF5,A0MZ66,P36507,P28482,P05387,O95239,O15144,P48556,Q9NR12,P29353,P19784,P04350,O75116,P62750,P62277,P62910,P62829,Q99436,P18077,Q92530,Q9Y5S9,P11940,P62244,Q04637,Q07020,Q15287,Q9Y3U8,Q14185,O15020,P67870,P35579,P62841,P62899,P51532,P35268,P15311,P25787,P46779,P26038,O94887,P42766,P62851,Q00610,P62917,P62913,P62263,Q9NWH9,P20618,Q9BZI7,P40429,P18124,P39023,P83881,Q01082,Q15008,P63173,P62424,P61160,P60953,P46939	95
Synthesis of diphthamide eef2	0.4459106875185031	0.3097909028729486	0.756719969985203	1.0	1.0	4	Q9H2P9,P13639	2
Deadenylation dependent mrna decay	0.4727207531594711	0.3071802737467373	0.7587061594238782	1.0	1.0	42	P38919,Q13868,Q969T7,Q04637,Q9H074,Q8IZH2,Q86TB9,Q9Y4Z0,P23588,Q9GZS3,Q9C0C2,P11940,Q06265,P26196,Q96C86,Q9Y2L1,O75175,Q6PGP7	18
G2 m dna damage checkpoint	0.46664988673019	0.3066251685469448	0.7591286941521709	1.0	1.0	40	Q92547,Q9UQ84,Q9BX63,P14635,P61088,O60921,Q13535	7
Phenylalanine metabolism	0.667667121418811	0.3046163820177336	0.7606583416093873	1.0	1.0	2	P61457	1
Adaptive immune system	0.2808328994585916	0.2942795773524728	0.7685442770038928	1.0	1.0	213	P19474,Q13177,O95487,O95782,P56377,P46934,P51665,Q63HN8,Q8N8S7,Q13362,P28070,P49721,Q9H0B6,P19174,Q13867,P06241,O94874,Q93034,P68036,Q13200,O00459,O43318,O75832,Q9BSL1,Q9BUF5,O94979,O43164,Q9UNE7,P61088,O95486,Q9UBG0,Q9UIQ6,P52907,Q9Y6G9,O95239,O94822,P48556,P52732,Q07866,Q15436,P09429,P04350,Q14203,Q10567,O00161,Q14738,Q13309,Q96CW1,Q9H1A4,Q6UWE0,Q9UJW0,Q7Z6E9,Q99436,Q9UJX4,O00232,Q92990,Q92530,Q96FJ2,Q13586,Q05086,Q13049,P61163,O94855,Q15345,Q14669,P62993,O15020,Q92692,Q8TBC4,Q15386,Q96J02,Q9UJX6,P25787,Q16763,Q00610,Q8NEZ5,Q9BXS5,Q9Y496,Q7Z6Z7,O15111,Q9ULT8,P20618,Q16537,Q9NSK0,O00139,P41240,Q5T4S7,Q13618,Q15008,P60953	90
M phase	0.25736573341377	0.2909720552165518	0.7710726919579087	1.0	1.0	210	P25787,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,Q86Y07,O75832,O15078,O60763,Q96FJ2,Q14683,O15504,P35658,P53350,P51665,Q9BVL2,Q14008,Q96EA4,Q96RT8,Q99986,Q13362,P28070,P49721,Q15154,P67870,Q9Y6G9,P50748,P20618,P23258,P19784,Q7Z460,P04350,Q9NTJ3,O43264,Q6KC79,Q14738,P49454,Q9Y6X3,Q14980,Q08379,Q96BD8,P12270,Q9H1A4,P14635,Q99436,Q8N3U4,Q9NTI5	49
Mtor signalling	0.3889451937036011	0.2862152639958531	0.7747132535763546	1.0	1.0	17	P23588,P54646,Q15382	3
Signaling by fgfr1 in disease	0.3747961263287203	0.2816933100156473	0.7781786846830934	1.0	1.0	13	Q92614,O94905,O15164,Q16630	4
Ptk6 regulates rho gtpases ras gtpase and map kinases	0.4106321711952027	0.2782390981026232	0.7808288233936624	1.0	1.0	5	P46108	1
Metabolism of amino acids and derivatives	0.1644414355674246	0.2722882686911994	0.7854003758018226	1.0	1.0	193	P62847,P25787,P46779,P78540,P18077,Q92530,O43252,O75832,P61247,P49591,P62244,P52758,P08708,P36957,P84098,P42766,O14874,P62851,P51665,Q07020,P46782,Q15046,Q16762,P62917,P62913,P62263,P28070,P34896,Q9Y3U8,Q9UDR5,P49721,P20618,O43324,P40429,Q16881,P18124,P62841,P62899,P39023,P62910,P62829,P83881,Q96H78,P35268,Q15008,P63173,Q99436,P61457	48
Cytokine signaling in immune system	0.1810296445185048	0.2700965377176937	0.7870859856611367	1.0	1.0	191	P25787,Q9UHD2,P19474,O60573,Q92530,O14733,O43318,O75832,P43378,Q9H0E2,O15504,P35658,Q15750,P46934,Q04637,P51665,Q9BVL2,P28070,P61088,O15111,P49721,O43432,Q9Y3Z3,P52907,P46108,P20618,Q8TBC4,P29353,P11233,P09429,P09661,P19174,P04083,O15344,P29372,Q14738,Q02750,P78344,P52294,P51532,P12270,Q93034,Q99436,O75925	44
Rhov gtpase cycle	0.3786554790699023	0.2691026819131504	0.7878506666697542	1.0	1.0	16	O43396,P46940,Q13813,Q03001,Q00610,Q13177,Q01082,P60953	8
Processing of capped intron containing pre mrna	0.2130229495157725	0.2690011592518196	0.7879287905845134	1.0	1.0	190	Q6UN15,Q15459,Q9P2I0,Q86XP3,O75152,Q9Y5S9,O60306,Q96QD9,Q05519,Q9UBB9,P51991,O60231,O15504,P35658,P62314,P35637,P52298,P67809,Q9BVL2,Q13573,Q8WUA2,Q99459,Q15287,Q9Y3Y2,Q7L014,Q16629,Q8IYB3,Q14103,O75400,Q9BZI7,P09661,Q9HCG8,P24928,Q9H2H8,O43395,O75533,Q9UQ35,P52756,Q08170,P84103,Q9BUJ2,Q92917,Q9C0J8,Q9Y4Z0,P12270,P13984,Q92620,Q96BP3,Q9HCS7	49
Regulation of tp53 activity through acetylation	0.3806518993532567	0.2667822343007069	0.7896368336322896	1.0	1.0	17	Q12873,Q92794,Q14839	3
Methylation	0.3563119853974777	0.2666232826909208	0.789759227379099	1.0	1.0	9	Q9NZL9	1
Cyclin a b1 b2 associated events during g2 m transition	0.3623803591625824	0.2664996670465936	0.7898544157943699	1.0	1.0	11	P63151,P06493,P14635,P53350	4
Rna polymerase i transcription	0.4072505370917256	0.2606605490645486	0.7943542918072231	1.0	1.0	27	Q86YP4,P17480,Q12873,Q14839	4
Activation of the ap 1 family of transcription factors	0.4846871346506874	0.2566742607510978	0.7974302429466604	1.0	1.0	3	P28482	1
Free fatty acids regulate insulin secretion	0.4828083482811744	0.2519435439236595	0.8010847017295999	1.0	1.0	3	P29992	1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects	0.6455661664392942	0.2509964237418606	0.8018168741469185	1.0	1.0	2	Q00534	1
Rrna processing	0.2958037582855849	0.2460705432223374	0.8056276252015833	1.0	1.0	169	P62847,Q9NQZ2,Q9NXF1,P61247,P08708,P46782,P46087,Q06265,P46777,Q9NRX1,P78346,Q01780,Q9NY93,P62753,P61254,P56182,Q96EU6,Q8WVM0,Q13868,P84098,Q9NR30,Q9NPE3,Q9BVI4,Q9Y2L1,Q9BVJ6,P42285,P05387,O43818,O60832,P62750,P62277,P78316,P62910,P62829,Q13895,Q9H0S4,P18077,Q2NL82,P19338,Q9UNQ2,Q9NV31,O15213,P62244,Q07020,P61353,Q14692,Q9H6R4,Q9Y3U8,Q8IWA0,Q9Y2X3,Q9H4L4,Q9H0A0,O43709,P62841,P62899,P35268,Q99848,Q96GA3,P61313,P46779,Q9Y4W2,Q8TED0,Q68CQ4,Q14137,P42766,Q9Y5J1,P62851,Q9H9L3,Q14690,Q13601,P62917,P62913,P62263,Q8IY37,Q9Y6V7,O15091,P26373,Q9Y2R4,P62424,P40429,P50914,P18124,Q9BQ52,Q8IY81,P39023,P83881,P63173,Q9Y221	88
Diseases of signal transduction by growth factor receptors and second messengers	0.2051056588672468	0.2438934994001435	0.8073133039116895	1.0	1.0	167	P25787,Q6UN15,Q92614,Q92530,P51608,O00203,O43252,O75832,P26038,P48729,O94905,O43815,P46940,O94979,Q15643,P52298,P51665,Q13573,Q00610,Q63HN8,Q13362,P28070,Q9NWH9,P32121,O15111,P49721,O15164,P20618,P29353,P24928,P19174,P18206,Q16537,Q8IWJ2,O00291,P35579,Q14738,P49841,Q02750,P84095,Q16630,Q92734,P51114,P41240,P12270,P56545,P13984,Q01082,Q99436	49
Signaling by hippo	0.3405482023016608	0.2437228347339896	0.8074454870073227	1.0	1.0	7	O14641,Q07157	2
Fgfr1 mutant receptor activation	0.3521743399644973	0.2429991767132054	0.8080060352284122	1.0	1.0	11	Q92614,O15164,Q16630	3
Ca2 pathway	0.3427779577861833	0.2419672768012968	0.8088055192165438	1.0	1.0	8	P09471,P63218	2
Phosphorylation of the apc c	0.3574759266715797	0.2416630996386474	0.8090412243653935	1.0	1.0	13	Q9UJX6,P53350,Q9H1A4,Q16763,P14635	5
Diseases of mitotic cell cycle	0.3596073484165311	0.2399312590848378	0.8103835472856666	1.0	1.0	14	Q9UJX6,Q9UJX4,Q13309,Q9UER7,Q9H1A4,Q16763,Q00534	7
Signaling by alk in cancer	0.4239787359781839	0.2393814016302904	0.8108098501864156	1.0	1.0	37	Q9HC35,P62753,P51608,P26038,O43815,O94979,P62993,Q00610,Q63HN8,P28482,Q07866,Q9P2E9,P29353,Q14203,P19174,P18206,Q8IWJ2,O00291,P35579,Q9NR09,P10644,Q92734,P12270	23
Extension of telomeres	0.4101649496466739	0.2389555545602136	0.8111400467588501	1.0	1.0	32	P18858,P35251,P51530,Q5H9R7,P41440,Q8WVB6,P35244,P49642,P27694,Q9NPE3,P28340,P12004,Q9NYB0,O60832,Q9BUR4,P15927,P40938	17
Protein ubiquitination	0.3962024820428996	0.2387212048643148	0.8113217729638265	1.0	1.0	27	Q5VTR2,P50542	2
Pi metabolism	0.3899537216777251	0.2374809559724673	0.8122836916125349	1.0	1.0	25	O95248,Q01968,Q08AM6,Q96T51,Q9HAU0,Q9UBF8	6
Tristetraprolin ttp zfp36 binds and destabilizes mrna	0.3494769614737794	0.2370770412721446	0.8125970231005295	1.0	1.0	11	Q9Y2L1,Q13868,Q8IZH2	3
Circadian clock	0.3490990217309485	0.2362569990110916	0.8132332522895325	1.0	1.0	11	P43490	1
Synthesis of pips at the plasma membrane	0.3603409933531684	0.2353292833693409	0.8139531683885479	1.0	1.0	15	Q96T51,Q9HAU0,Q01968	3
Grb2 sos provides linkage to mapk signaling for integrins	0.6384720327421592	0.234875566576792	0.8143053141773458	1.0	1.0	2	Q9Y490	1
Met activates pi3k akt signaling	0.6384720327421434	0.2348755665767569	0.8143053141773731	1.0	1.0	2	Q9NWH9	1
Cell cycle checkpoints	0.3418860494913259	0.2330295018126466	0.8157384971675414	1.0	1.0	157	Q9UJX6,P25787,Q9H900,Q9UQ84,Q9Y6D9,Q9Y266,O43683,Q9H3R5,Q92530,Q16763,Q9BX63,O75832,P42771,P46060,Q96FJ2,Q92547,P53350,Q13472,P51665,Q14008,Q96EA4,Q7L590,Q53HL2,Q13362,P28070,P61088,P49721,O00311,Q9Y6G9,P50748,P20618,Q7Z460,Q13535,P51530,O14757,O43264,Q14738,P49454,Q96BD8,P38398,Q9H1A4,P14635,Q99436,Q8WYP5,O60921	45
Regulation of tp53 activity	0.4856613602759441	0.2306349026046061	0.8175984501475833	1.0	1.0	64	Q92547,Q12873,Q9UQ84,P67870,Q9UER7,Q86YP4,Q9HBM6,Q14839,P54646,Q9BX63,Q13362,Q92794,Q9Y5B9,P42771,O60921,Q13535	16
Regulation of pten localization	0.6365620736698436	0.2306285556943011	0.8176033813422197	1.0	1.0	2	P46934	1
Energy dependent regulation of mtor by lkb1 ampk	0.3403119007587717	0.2299606308942109	0.8181223619004394	1.0	1.0	9	Q15382	1
Map2k and mapk activation	0.3574661159689618	0.2294029676650098	0.8185557297996051	1.0	1.0	15	P10398,P28482,Q02750,P46940,Q9UHA4,P41240,Q9Y490,P18206,P32121,P36507	10
Signaling by fgfr in disease	0.3826146954850896	0.2288381774873885	0.8189946926610863	1.0	1.0	24	Q16630,P52298,Q92614,O15164,P13984,P24928,O94905	7
Signal transduction by l1	0.3425282501872336	0.2284435676344278	0.8193014226604356	1.0	1.0	10	P28482,P27361,Q02750,O14786,P67870,P19784,P36507	7
Endosomal sorting complex required for transport escrt	0.3498230530324648	0.2255369003596764	0.8215616223978253	1.0	1.0	13	Q99816,Q9BRG1,Q9UQN3,Q9NZZ3,O14964,Q9H9H4	6
Signaling by notch3	0.3406001844803283	0.224379506457606	0.8224620156531097	1.0	1.0	10	O00308,P67809,Q9Y6A5,Q15398	4
Mitotic metaphase and anaphase	0.3071533135041222	0.224352803609298	0.8224827918676256	1.0	1.0	149	Q9UJX6,P25787,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,Q86Y07,Q16763,O75832,P06493,P46060,Q96FJ2,Q14683,P53350,P51665,Q9BVL2,Q14008,Q96EA4,Q99986,Q53HL2,Q13362,P28070,P49721,Q9Y6G9,P50748,P20618,Q7Z460,P04350,O43264,Q14738,P49454,Q96BD8,Q9H1A4,P14635,Q99436,Q8WYP5,Q8N3U4,Q9NTI5	40
Mrna splicing	0.22680788747333	0.2232684350203915	0.8233265924205986	1.0	1.0	148	Q6UN15,Q15459,Q9P2I0,Q86XP3,Q9Y5S9,O60306,Q05519,Q9UBB9,P51991,O60231,P62314,P35637,P52298,P67809,Q13573,Q8WUA2,Q99459,Q15287,Q7L014,Q16629,Q8IYB3,Q14103,O75400,Q9BZI7,Q9HCG8,P09661,P24928,Q9H2H8,O43395,O75533,Q9UQ35,P52756,Q08170,P84103,Q9BUJ2,Q92917,Q9C0J8,Q9Y4Z0,P13984,Q92620,Q96BP3,Q9HCS7	42
Notch3 activation and transmission of signal to the nucleus	0.3486110613127816	0.2225501353531026	0.8238856492877364	1.0	1.0	6	P67809,O00308	2
Glycogen storage diseases	0.4704953629231045	0.222016122921229	0.8243013322503732	1.0	1.0	3	P46976	1
Signaling by cytosolic fgfr1 fusion mutants	0.3364191399030358	0.2216988886538811	0.8245482953130405	1.0	1.0	9	O15164,Q16630	2
Hsf1 activation	0.3559674861390284	0.2207376758801503	0.8252966938501216	1.0	1.0	16	Q15185,Q02790,P35244,P27694,P04792,Q92598,P15927,O75190	8
Negative epigenetic regulation of rrna expression	0.3780711207293113	0.2204746703204811	0.8255014972049828	1.0	1.0	24	P32780,P26358,Q96ST3,P19447,P17480,Q9UHR5,O60264,Q13547	8
Sema3a pak dependent axon repulsion	0.3354403086947354	0.2196624748114597	0.8261340316127297	1.0	1.0	9	O14786,P08238,P07900,Q16512,Q13177,P06241	6
Transcriptional regulation by tp53	0.3031326966913196	0.2178587345887175	0.8275391798831568	1.0	1.0	143	Q9UQ84,P19447,Q14839,Q9BX63,Q9Y5B9,P42771,Q14241,Q92547,P15954,Q9UER7,Q13472,Q13362,Q15382,O00267,P67870,P55199,Q9NYV4,Q9HBM6,Q92794,Q13535,Q16881,Q92696,Q12873,Q86YP4,P54646,P23193,P14635,O75175,O60921	29
Hiv infection	0.2611948223905908	0.2178570338455019	0.8275405050560809	1.0	1.0	143	P18858,Q99816,P25787,P19447,O75832,Q9Y5B9,P29083,Q14241,O95782,P56377,O15504,P35658,P52298,P51665,Q9BVL2,P17096,P28070,Q9BXS5,O00267,P49721,P55199,Q9HBM6,P20618,P24928,Q00403,P12270,P13984,P23193,Q93034,Q99436	30
Initiation of nuclear envelope ne reformation	0.3580404585784261	0.2140426956522995	0.8305137623153278	1.0	1.0	18	Q86Y07,P14635	2
Deactivation of the beta catenin transactivating complex	0.3351797622173337	0.2132939656308525	0.8310976799952388	1.0	1.0	10	Q04727	1
Signaling by robo receptors	0.324009155164802	0.2124602754205483	0.8317479659316716	1.0	1.0	138	P62847,Q13200,P25787,P46779,P62753,P61254,P18077,Q92530,Q13177,Q9Y5S9,P11940,O75832,P61247,P62244,P08708,P84098,P42766,Q04637,P52298,P51665,Q07020,P46782,P62851,P62917,P62913,P62263,Q8N8S7,P28070,Q15287,Q01518,P46777,P38919,Q9Y3U8,P49721,P05387,P48556,P20618,Q9BZI7,Q7Z460,P62424,P40429,P62750,O94813,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,Q15008,P63173,Q99436,P60953	55
Thromboxane signalling through tp receptor	0.3808643053488065	0.2112034554835308	0.8327285144866243	1.0	1.0	5	P63218	1
Hiv transcription initiation	0.3537111865283208	0.2111476375048346	0.8327720687287996	1.0	1.0	17	Q00403,P19447,Q9HBM6,P13984,P29083	5
Rhobtb gtpase cycle	0.3881773245768731	0.2103132290535678	0.8334232108913813	1.0	1.0	30	Q8IYB3,Q5VTR2,P12814,Q96T58,O75116,Q7Z6E9	6
Rhof gtpase cycle	0.3640075950019387	0.2099550425198636	0.8337027617836594	1.0	1.0	21	Q9P0U3,Q9UEY8,Q07960,Q02952,Q9Y4F1,P80723,Q9NSV4,Q13017,P12814,O00161	10
Signaling by receptor tyrosine kinases	0.1811702024081364	0.209211594923879	0.834283061267739	1.0	1.0	135	Q96F07,O00459,Q13177,Q14839,Q8WX92,Q9Y6W5,Q9Y5K8,Q9Y6I3,Q96S59,P04792,Q8WUW1,P07942,O60610,P14923,O95782,Q99570,Q13685,P46934,P52298,P31483,Q9UNE7,Q00610,Q96N67,Q9NWH9,P38606,P36507,O75348,P28482,Q14185,P46108,P35221,P29353,P11233,P24928,O75116,P19174,Q9UQB8,Q13547,Q05655,O14757,Q14738,Q96ST3,Q02750,Q13464,P41240,P21283,P13984,P06241,Q93034,Q96J02,P60953	51
Homology directed repair	0.4343842312126503	0.2090177943658267	0.8344343475191707	1.0	1.0	49	P35251,Q9UGN5,Q9UQ84,Q9BX63,P49916,Q92547,P60510,Q13472,P61088,Q92889,P15927,P40938,Q92878,P41440,P28340,P51530,Q13535,Q9NXR7,O14757,Q07864,P35244,P38398,P09874,P12004,O60921	25
Signaling by ptk6	0.3413253856530061	0.2087705289975437	0.8346273788255472	1.0	1.0	13	O75525	1
Translocation of slc2a4 glut4 to the plasma membrane	0.4097511285791912	0.2082722503729163	0.8350163975433693	1.0	1.0	39	P35579,O60343,Q9UIQ6,Q96A65,Q8TAG9,Q8IYI6,P11233,P54646,P04350,Q9Y496	10
Response of eif2ak1 hri to heme deficiency	0.4639737991266482	0.2069391805017079	0.8360573571290582	1.0	1.0	3	P08243,P20042	2
Rho gtpase effectors	0.3565711978691879	0.2038867491222173	0.8384420002518775	1.0	1.0	130	Q9H900,Q9Y266,Q9Y6D9,O43683,Q96F07,Q9H3R5,Q13177,Q9NSV4,Q9Y6W5,Q8WUM0,P46060,Q96FJ2,Q9BZD4,Q8WUW1,O60610,Q99570,Q9BUF5,P46940,P53350,Q16513,Q14008,O60879,Q96EA4,Q53HL2,Q13362,Q9HD26,O14974,P28482,O14641,Q96EE3,Q9H0B6,Q9Y6G9,P50748,O15144,Q14247,P35221,Q07866,Q9NZQ3,Q7Z460,P04350,O75116,Q13576,Q9UQB8,Q16537,Q9NSK0,Q8WYP5,O43264,P35579,Q9H081,Q14738,P49454,O60341,P84095,Q13464,O00139,Q96BD8,P21333,O14777,P60953,P61160	60
Class i mhc mediated antigen processing presentation	0.3352461565026579	0.2027695925158841	0.8393151258515712	1.0	1.0	129	P25787,Q92990,P19474,Q92530,O75832,O95487,Q05086,O94855,P46934,O94979,O43164,P51665,Q63HN8,Q8NEZ5,P28070,P61088,O95486,Q9UBG0,O15111,P49721,Q9UIQ6,O94822,P20618,Q8TBC4,P09429,O00161,Q15386,Q13309,Q13867,Q9H1A4,Q93034,Q7Z6E9,Q99436,Q5T4S7	34
Dna repair	0.3110267169090976	0.201671274213969	0.840173721012546	1.0	1.0	128	P18858,P35251,Q9UQ84,Q9UGN5,P19447,Q13620,Q9H981,Q9BX63,O60306,Q8N9N2,Q5UIP0,P49916,Q9H1I8,Q92547,Q6ZW49,P60510,Q96T60,Q13472,P61088,Q92889,Q6P6C2,Q8TAT6,Q9H9Q2,P52701,Q92878,P41440,P55199,Q9NVI1,P24928,P28340,O00213,Q13535,Q9NXR7,P51530,O14757,P27695,Q86WJ1,P29372,Q07864,Q04323,P35244,P38398,P09874,Q14258,P12004,P23193,Q99627,P20585,Q9HCS7,O60921,O75925	51
Retrograde transport at the trans golgi network	0.3591720131351392	0.2015918053735797	0.8402358520715079	1.0	1.0	21	P82094,Q96MW5,Q8WTW3	3
Influenza infection	0.2136224829420343	0.199504302004804	0.8418682784825593	1.0	1.0	126	P62847,P46779,P62753,P61254,P18077,P61247,Q8WUM0,P62244,P08708,O15504,P19525,P84098,P35658,P42766,P62851,Q9BVL2,P46782,Q07020,Q00610,P62917,P62913,P62263,Q8TEM1,P49790,P46777,Q9Y3U8,Q96EE3,P05387,P24928,P40429,P62750,P18124,P62841,P62899,P52294,P62910,P62829,P39023,P83881,P09874,P35268,P13984,P12270,P63173,P62424	45
Hiv transcription elongation	0.3708342162459968	0.1991893156896742	0.8421146568078222	1.0	1.0	26	Q14241,P19447,P52298,P55199,P13984,P23193,P24928,Q9Y5B9,P50750,O00267	10
Regulation of expression of slits and robos	0.335286171974939	0.1973984003701547	0.8435157813137686	1.0	1.0	124	P62847,Q13200,P25787,P46779,P62753,P61254,P18077,Q92530,Q9Y5S9,P11940,O75832,P61247,P62244,P08708,P84098,P42766,Q04637,P52298,P51665,Q07020,P46782,P62851,P62917,P62913,P62263,P28070,Q15287,P46777,P38919,Q9Y3U8,P49721,P05387,P48556,P20618,Q9BZI7,P62424,P40429,P62750,O94813,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,Q15008,P63173,Q99436	50
Notch4 intracellular domain regulates transcription	0.4591844398012774	0.1962162628098688	0.8444408995931643	1.0	1.0	3	Q13573	1
Regulation of pten gene transcription	0.3688583078712909	0.1960905716142038	0.8445392757667007	1.0	1.0	26	O95983,Q12873,Q9HC52,Q9UHA4,Q86YP4,Q14839,Q15910,Q8WXI9,Q14781,Q15382	10
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function	0.3288992609419559	0.1959411719697234	0.8446562112582552	1.0	1.0	11	O15047	1
Parasite infection	0.3688272742932565	0.1921602238217383	0.8476167020080339	1.0	1.0	27	P28482,Q14185,P35579,P46108,Q96F07,O15144,P62993,Q9NZQ3,Q9Y6W5,P06241,Q9UQB8,P61160,P60953,Q8WUW1	14
Dap12 interactions	0.3212699973943765	0.1920373503906872	0.847712948496061	1.0	1.0	9	O00459,P62993,P29353,P06241,P19174	5
Formation of the beta catenin tcf transactivating complex	0.329347062945432	0.1918477074040025	0.8478614998870819	1.0	1.0	12	Q04727	1
Intraflagellar transport	0.3358121270407094	0.1891132506848391	0.8500040563323126	1.0	1.0	15	Q15643,P04350,Q9Y496,Q8NCM8,Q96FJ2	5
Separation of sister chromatids	0.3641719581952172	0.1869205682869145	0.8517229122554535	1.0	1.0	114	Q9UJX6,Q13200,P25787,Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,Q92530,Q16763,Q9UQE7,O75832,Q8WUM0,P46060,Q96FJ2,Q9BZD4,O60216,Q14683,P53350,P51665,Q14008,Q96EA4,Q53HL2,Q13362,P28070,P49721,Q96EE3,Q9Y6G9,P50748,P20618,Q7Z460,P04350,Q16537,Q8WYP5,O43264,Q9H081,Q14738,P49454,O00139,Q96BD8,Q9H1A4,Q15008,Q99436,O14777,Q8N3U4,Q9NTI5	46
Raf activation	0.3340804865447425	0.1862230635294639	0.8522698382177305	1.0	1.0	15	Q14738,Q02750,Q13362,Q16537,P36507	5
Runx2 regulates osteoblast differentiation	0.6150068212824052	0.185502054459963	0.8528352690057461	1.0	1.0	2	P28482	1
Hiv elongation arrest and recovery	0.3483773955913029	0.1842314535862793	0.8538318853846179	1.0	1.0	21	Q14241,P55199,P13984,P23193,P24928,Q9Y5B9,P50750,O00267	8
Polb dependent long patch base excision repair	0.3110854583618326	0.183507975321603	0.8543994616303503	1.0	1.0	7	P18858,P27695,P09874	3
Gap filling dna repair synthesis and ligation in gg ner	0.3420089022770637	0.1822890712775579	0.8553558748540708	1.0	1.0	19	P18858,P35251,Q07864,P41440,P35244,P40938,P12004,P28340,P15927,P49916	10
Signaling by type 1 insulin like growth factor 1 receptor igf1r	0.3129448557635146	0.1820147038673577	0.8555711866326348	1.0	1.0	8	Q99570,O00459,P29353,P62993	4
Resolution of ap sites via the multiple nucleotide patch replacement pathway	0.3517535900573874	0.1817423394221513	0.8557849372054391	1.0	1.0	23	P18858,P35251,Q9UGN5,Q07864,P41440,P35244,P09874,P12004,P28340,P15927,P40938,P27695	12
Resolution of sister chromatid cohesion	0.4448414641743431	0.1815988151154809	0.8558975787891812	1.0	1.0	68	O14777,Q9Y266,Q9H900,Q9Y6D9,O43683,Q9H3R5,Q9UQE7,P06493,Q8WUM0,P46060,Q96FJ2,Q9BZD4,O60216,Q14683,P53350,Q14008,Q96EA4,Q53HL2,Q13362,Q96EE3,Q9Y6G9,P50748,Q7Z460,P04350,Q16537,O43264,Q14738,Q9H081,P49454,O00139,Q96BD8,P14635,Q8WYP5,Q8N3U4,Q9NTI5	35
P75ntr negatively regulates cell cycle via sc1	0.6128240109140559	0.1812239887635479	0.8561917660336407	1.0	1.0	2	Q13547	1
Perk regulates gene expression	0.3247890217489648	0.1795974530785156	0.8574686043194999	1.0	1.0	13	P20042,Q9Y2L1,Q13868,Q06265	4
Programmed cell death	0.232906502858994	0.1790727703751244	0.8578805624834962	1.0	1.0	107	P15924,P49721,P25787,P26583,Q15149,P41440,P09429,P28070,Q99436,P42771,Q96FJ2,O76075,Q14790	13
Nuclear events stimulated by alk signaling in cancer	0.3212895711541855	0.1781599793891239	0.8585973386651928	1.0	1.0	12	P28482,P27361,Q9HC35,P62753,Q00610,P51608	6
Interleukin 1 family signaling	0.4175079632925522	0.1768239058160069	0.8596467108055681	1.0	1.0	55	O15111,P25787,P49721,Q02750,Q9UHD2,P51665,Q92530,P43378,P20618,P09429,O43318,P28070,O75832,P61088,Q99436,Q9H0E2	16
Positive epigenetic regulation of rrna expression	0.3672559939825173	0.1765563560445043	0.8598568782471765	1.0	1.0	31	Q9NY93,Q13185,Q92769,Q14839,Q9UIG0,Q9NR30,Q8WXI9,O00159,Q96KQ7,P62805,Q09028,Q9BQG0,Q13547,O95983,Q12873,P49841,O75533,Q86YP4,O60264	19
Egfr downregulation	0.3121035560911142	0.1760191716360701	0.8602788808105362	1.0	1.0	9	P60953,O14964,P62993,Q9Y6I3	4
Chromatin modifying enzymes	0.4500646713924117	0.1759864062288793	0.8603046220268911	1.0	1.0	85	O14497,Q86TU7,Q12873,Q9H7B4,O15047,Q92925,O75486,Q9NPF5,Q86YP4,Q14839,Q6VMQ6,Q9UPT9,Q9H9T3,Q92794,Q9UBL3,Q8NEM7,Q8IUF8	17
Miscellaneous transport and binding events	0.3111960032516971	0.1745121116562133	0.8614630130900021	1.0	1.0	9	Q8TDW0,Q9HD23	2
Epigenetic regulation of gene expression	0.3956466178597601	0.1742008841123973	0.8617075907401615	1.0	1.0	45	P32780,P19447,Q9NY93,Q13185,Q92769,Q14839,Q9UHR5,Q9UIG0,P26358,Q9NR30,Q8WXI9,O00159,Q96KQ7,P62805,Q09028,Q15910,Q9BQG0,Q13547,Q15022,O95983,Q12873,Q96ST3,P49841,O75533,P17480,Q86YP4,O60264	27
Eukaryotic translation initiation	0.3754655974459114	0.1738779092632111	0.8619614140111236	1.0	1.0	101	P62847,Q9UBQ5,P46779,P62753,P61254,P18077,O15372,P11940,P61247,P55884,P62244,P56537,P08708,P84098,P42766,Q04637,Q14152,P62851,Q07020,P46782,Q13144,P62917,P62913,P62263,P60228,P46777,Q9Y3U8,P05387,P23588,Q14232,P40429,P62750,P62277,O75821,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P20042,O75822,P63173,P62424,O60841,Q9NR50	48
Semaphorin interactions	0.3509551171452701	0.173751072889832	0.8620610975707781	1.0	1.0	25	P35579,O94887,P49841,Q13464,Q14195,Q13177,Q9Y490,Q9NWH9,O75116	9
Mitotic prometaphase	0.3073900944691332	0.1727459737223075	0.8628511051749044	1.0	1.0	101	Q9H900,Q9Y266,Q9Y6D9,O43683,Q9H3R5,O95347,P06493,P46060,O15078,Q96FJ2,Q14683,P53350,Q14008,Q96EA4,Q96RT8,Q53HL2,Q13362,Q15154,P67870,Q9Y6G9,P50748,Q9BPX3,P23258,P19784,Q7Z460,P04350,Q9NTJ3,O43264,Q14738,P49454,Q14980,Q96BD8,P14635,Q8WYP5,Q8N3U4,Q9NTI5	36
Antigen processing ubiquitination proteasome degradation	0.3708394703950597	0.1727223649608362	0.8628696633053619	1.0	1.0	100	Q9UJX6,Q13200,Q9UJX4,P25787,P25788,Q99460,O00232,Q92990,P19474,Q92530,Q8TDB6,Q16763,O75832,Q05086,Q13049,Q9BSL1,P46934,O43164,Q9UNE7,P51665,Q15345,Q14669,Q9UII4,Q63HN8,Q8NEZ5,P28070,P61088,Q7Z6Z7,P49721,Q9UIQ6,O94822,Q9ULT8,P29144,P48556,Q8TBC4,P62333,P20618,P63208,Q7Z6E9,P49427,Q15386,Q13309,Q13867,Q9H1A4,Q6UWE0,Q13618,Q96J02,O94874,Q93034,Q99436,P61086,Q5T4S7,Q15008,Q06323,P68036	55
Signaling by vegf	0.3682999568160009	0.1722286650585867	0.863257763128682	1.0	1.0	33	P14923,Q14185,Q13685,Q13464,P46108,O00459,Q96F07,Q13177,P35221,Q9Y6W5,P04792,P06241,O75116,P19174,Q9UQB8,P60953,Q8WUW1	17
Intracellular signaling by second messengers	0.3303018514869255	0.1718590755253222	0.8635483208100352	1.0	1.0	100	Q13200,P25787,P25788,P27361,Q9HC52,Q9UHA4,Q99460,O00232,O00459,Q92530,Q14839,O75832,O00308,O43815,P46934,Q9UNE7,P51665,P62993,Q8WXI9,Q13362,P28070,Q93009,Q9NWH9,Q15382,P28482,O15111,P49721,P67870,P48556,P20618,Q15910,P19784,P19174,Q13547,Q16537,Q05655,Q15022,O95983,P10644,Q14738,Q12873,P49841,O60341,P84095,Q86YP4,O43865,P06241,Q14781,Q15008,Q99436,Q06323	51
S phase	0.2729108115295829	0.170519354329511	0.8646017147029956	1.0	1.0	99	P18858,Q13200,Q9UJX4,P49643,P25787,P35251,Q9UJX6,P25788,Q99460,O00232,Q92530,P27694,Q16763,Q9Y248,Q9UQE7,O75832,P11802,O60216,Q14683,P51665,O43913,P49642,Q5TKA1,P33991,P28070,P25205,P15927,P40938,P49721,Q9BRX5,P41440,P62333,P48556,P20618,Q09028,P28340,P51530,P49841,Q13309,Q07864,P35244,Q9H1A4,P12004,Q15008,Q99436,Q8N3U4,Q06323,Q9NTI5	48
Telomere maintenance	0.3845011600702239	0.1690348733179341	0.8657692111274715	1.0	1.0	42	P18858,P35251,Q5H9R7,Q9UER7,P41440,Q8WVB6,P35244,P49642,Q9NPE3,P28340,P12004,P24928,O60832,Q9BUR4,P15927,P51530	16
Hedgehog on state	0.3864235090124745	0.1689694848490674	0.8658206438042166	1.0	1.0	43	P25787,P49721,P32121,P51665,Q92530,P20618,Q13618,P28070,O75832,Q96J02,Q99436,P48729,Q9Y496	13
Trna modification in the nucleus and cytosol	0.3329489192935834	0.1689599919448778	0.8658281106950947	1.0	1.0	19	Q9H974,Q7Z4G4,Q96PZ0,Q9UBP6	4
Mitotic g2 g2 m phases	0.2728778692040071	0.168382238068748	0.8662825805654009	1.0	1.0	97	P49721,Q15154,P49454,P25787,P53350,Q14008,Q96RT8,Q5TKA1,Q7Z460,P28070,P14635,Q99436,O15078,O14974	14
Mapk family signaling cascades	0.2680861253514512	0.1683750805097714	0.8662882110862931	1.0	1.0	97	Q13200,P25787,Q9UHA4,O00459,Q92530,Q13177,Q9Y490,Q96S59,O75832,P04792,P06493,P46940,P51665,Q13362,P28070,Q9NWH9,P32121,P36507,P28482,P49721,O15020,P48556,P20618,P29353,Q14168,P18206,Q16537,Q14738,Q02750,Q13813,P41240,Q13618,Q01082,P06241,Q15008,Q99436,P60953	37
Tp53 regulates transcription of genes involved in g2 cell cycle arrest	0.3095010939285976	0.1676193368032804	0.8668827578652742	1.0	1.0	10	O14965,P06493,P14635	3
Host interactions of hiv factors	0.2466892314712468	0.1672864523213358	0.8671446634134579	1.0	1.0	96	P25787,Q92530,O75832,P46060,O75475,O95782,P56377,O15504,P35658,P51665,Q9BVL2,P17096,P28070,Q9BXS5,P49721,P20618,P12270,Q93034,Q99436	19
Signaling by wnt	0.3150891218160915	0.1664581969085575	0.8677963781917215	1.0	1.0	95	P25787,Q92530,O43318,O75832,P48729,O95782,P09471,P51665,Q96QK1,Q00610,Q13362,P28070,Q9UBL3,P32121,O14641,P49721,P67870,P20618,P19784,O60493,Q16537,Q14738,P49841,P60763,P51532,P63218,P56545,Q04727,Q13618,Q99436	30
Formation of rna pol ii elongation complex	0.3604426916030929	0.1656696858321274	0.8684169035427554	1.0	1.0	32	Q14241,Q7KZ85,P19447,P52298,Q6PD62,P55199,P13984,P23193,P24928,Q9Y5B9,P50750,O00267	12
Dna replication	0.2519793414644682	0.165150778010951	0.8688253066207179	1.0	1.0	94	P18858,Q13200,Q9UJX4,P49643,P25787,P35251,Q9UJX6,P25788,O00232,Q92530,P27694,Q16763,Q9Y248,O75832,P51665,O43913,P49642,Q7L590,P33991,P28070,P15927,P40938,P49721,O00311,Q9BRX5,P41440,P48556,P20618,P28340,P51530,O60684,Q13309,Q07864,P52294,P35244,Q9H1A4,P12004,Q15008,Q99436,Q06323	40
Apoptosis	0.2432468887317024	0.1651446811650045	0.8688301053125249	1.0	1.0	94	P15924,P49721,P25787,P26583,Q15149,Q13464,P51665,Q07157,P20618,P09429,P28070,O75832,Q99436,P42771,Q96FJ2,O76075,Q14790	17
Inactivation of csf3 g csf signaling	0.3557714924015591	0.1641856724966457	0.8695849797395854	1.0	1.0	5	Q93034,P42224	2
Rhob gtpase cycle	0.3492108311949046	0.1628559131363974	0.8706318835379363	1.0	1.0	28	P14923,Q9UDY2,Q9H2G2,Q07960,Q9NQW6,Q13464,Q16513,P41440,Q9NSV4,Q9H8V3,Q13017,O75116,O00161,O60610	14
Metalloprotease dubs	0.354955160012761	0.1628058927009595	0.8706712684707185	1.0	1.0	5	P38398,Q15018	2
G2 m checkpoints	0.3355360052284545	0.1626524390247093	0.8707920963434943	1.0	1.0	91	P49721,Q92547,P25787,O00311,Q9UQ84,Q13472,Q9BX63,P28070,P61088,P14635,Q99436,O60921,Q13535	13
Cellular response to starvation	0.3326169870228532	0.1625834801762305	0.870846394825703	1.0	1.0	91	P62847,P46779,Q9UHA4,P62753,P61254,P18077,Q9Y5K8,P61247,P62244,P08708,P84098,P42766,P62851,Q07020,P46782,P62917,P62913,P62263,Q15382,P38606,P46777,O75348,Q9Y3U8,Q96EE3,P05387,P40429,P62750,P18124,P62841,Q92616,P62899,P39023,P62910,P62829,P83881,P21283,P20042,P35268,P63173,P62424	40
Metabolism of vitamins and cofactors	0.3954114101345981	0.1616839965583855	0.8715547076091632	1.0	1.0	53	O75874,Q969G6,P49914,P35270,P41440,Q9NRN7,P35030,P05165,P34897,P50747,Q8NFF5,Q96CD2,P34896,P43490,O00763	15
Selenoamino acid metabolism	0.3170611030818104	0.1612652706391286	0.8718844752167099	1.0	1.0	90	P62847,P46779,P62753,P61254,P18077,O43252,P61247,P49591,P62244,Q13155,P08708,P84098,P42766,P62851,Q15046,Q07020,P46782,P62917,P62913,P62263,P46777,Q9Y3U8,P05387,O43324,P40429,P62750,Q16881,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P63173,P62424	37
Sars cov infections	0.4066056029629118	0.1597877285237004	0.873048291092648	1.0	1.0	66	Q99720,Q12873,Q9UHD2,P78362,Q14839,O75116	6
Nonsense mediated decay nmd	0.360069260894067	0.1597673778056145	0.8730643226708072	1.0	1.0	87	P62847,P46779,P62753,P61254,P18077,Q9Y5S9,P11940,P61247,P62244,P08708,P84098,P42766,Q04637,P52298,P62851,Q07020,P46782,P62917,P62913,P62263,Q15287,P46777,P38919,Q9Y3U8,P05387,Q9BZI7,P40429,P62750,P62277,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P63173,P62424	39
Regulation of runx3 expression and activity	0.3651171323470571	0.1596770065950326	0.8731355145536817	1.0	1.0	37	P25787,P49721,P51665,P20618,P28070,O75832,Q99436,P42771	8
Synthesis of dna	0.2354598102167126	0.1576573625277703	0.8747267999826545	1.0	1.0	87	P18858,Q13200,Q9UJX4,P49643,P25787,P35251,Q9UJX6,P25788,Q99460,O00232,Q92530,P27694,Q16763,Q9Y248,O75832,P49736,P49005,P51665,O43913,P35998,P49642,P33991,P28070,P25205,P15927,P40938,P49721,Q9BRX5,P41440,P62333,P48556,P20618,P63208,P28340,P51530,Q13309,Q07864,P35244,Q9H1A4,P12004,Q15008,Q99436,Q06323	43
Rho gtpases activate formins	0.4015220630777736	0.157158538234558	0.8751199038701682	1.0	1.0	69	Q9Y266,Q9H900,Q9Y6D9,O43683,Q9H3R5,Q9NSV4,Q8WUM0,P46060,O60610,Q96FJ2,Q9BZD4,P53350,Q14008,O60879,Q96EA4,Q53HL2,Q13362,O14641,Q96EE3,Q9Y6G9,P50748,Q7Z460,P04350,Q16537,Q8WYP5,O43264,Q14738,Q9H081,P49454,O00139,Q96BD8,O14777,P60953	33
Metabolism of nucleotides	0.3839602165579965	0.1566098591845614	0.8755523319276237	1.0	1.0	50	P04818,Q9H773,O76075	3
Sumoylation	0.2779253454872689	0.1556393005834354	0.8763173450216344	1.0	1.0	85	Q9P0U3,Q9HC52,O14965,Q9UQE7,P42771,P46060,O60216,Q14683,P26358,O15504,P35658,Q9UER7,Q9BVL2,Q53HL2,Q8TEM1,P49790,Q96EE3,Q9UBT2,P45973,Q96MG7,P11388,Q12873,Q96ST3,O75928,Q02880,P38398,P09874,P12270,Q13263,Q14781,Q8N3U4,O75925	32
Hiv life cycle	0.2489213583531632	0.1555395772180894	0.8763959554695897	1.0	1.0	85	P18858,Q99816,P19447,Q9Y5B9,P46060,P50750,P29083,O75475,Q14241,O15504,P35658,P52298,Q9BVL2,P17096,Q9H9H4,O00267,Q9H3P2,P55199,Q9HBM6,P24928,Q00403,P12270,P13984,P23193	24
Ripk1 mediated regulated necrosis	0.3046479709200623	0.1533032546822275	0.8781591341505377	1.0	1.0	12	P41440	1
Atf4 activates genes in response to endoplasmic reticulum stress	0.3015532071851149	0.1523590210081632	0.878903776179097	1.0	1.0	11	Q9Y2L1,Q13868,Q06265	3
Rhoq gtpase cycle	0.3311446433155697	0.1522140602523957	0.8790181047046641	1.0	1.0	24	P14923,Q07960,P46940,Q9NSV4,Q13017,O00308,Q9HD26	7
Regulation of pten stability and activity	0.3687748531237452	0.1521023250010497	0.8791062304602246	1.0	1.0	44	P25787,P49721,P46934,P67870,P51665,P20618,P19784,P28070,O75832,Q99436,O00308	11
Cross presentation of soluble exogenous antigens endosomes	0.3586328482792328	0.152015799599865	0.8791744741992511	1.0	1.0	38	P25787,P49721,P51665,P20618,P28070,O75832,Q99436,Q9UBG0	8
Mitotic g1 phase and g1 s transition	0.3017587073933857	0.1517253648308074	0.8794035505393765	1.0	1.0	81	Q13200,P49643,P25787,P25788,Q99460,O00232,Q92530,P27694,P11802,O75832,P42771,P04818,P06493,P51665,O43913,P49642,Q5TKA1,Q7L590,P33991,P28070,P25205,P15927,Q00534,P49721,O00311,P62333,P48556,P20618,Q09028,Q13547,P11388,P63151,Q13309,Q07864,P35244,P12004,P14635,Q15008,Q99436,Q06323	40
Rhou gtpase cycle	0.3188477740015639	0.1507020821684623	0.8802107306628542	1.0	1.0	19	O43396,P60953,P46940,Q13813,Q93008,Q03001,O00459,Q13177,Q00610,Q01082,O00308	11
Mitotic spindle checkpoint	0.3841181516351626	0.150472591237938	0.8803917735380102	1.0	1.0	64	Q9UJX6,Q9Y266,Q9H900,Q9Y6D9,O43683,Q9H3R5,Q16763,P46060,Q96FJ2,Q9BZD4,P53350,Q14008,Q96EA4,Q53HL2,Q13362,Q96EE3,Q9Y6G9,P50748,Q7Z460,Q16537,Q8WYP5,O43264,Q14738,Q9H081,P49454,O00139,Q96BD8,Q9H1A4,O14777	29
Ub specific processing proteases	0.2070038757672408	0.1501669718742019	0.8806328830033714	1.0	1.0	80	P49721,P25787,O94966,P54578,Q96FW1,Q9HBM6,Q9UPT9,P28070,Q9NZL9,Q99436,P32121	11
Transcription of the hiv genome	0.3453957949257434	0.1500844580870449	0.880697981742341	1.0	1.0	32	Q14241,Q00403,P19447,P52298,P55199,Q9HBM6,P13984,P23193,Q9Y5B9,P29083,O00267	11
Factors involved in megakaryocyte development and platelet production	0.3737361441875517	0.1491328913600136	0.8814487725379736	1.0	1.0	51	Q9BUF5,Q96Q89,Q96N67,Q9Y496,Q9NRW7,Q14185,Q9H0B6,P45973,P52907,O95239,P52732,Q07866,P04350,Q9NSK0,Q96ST3,O60341,Q13572,O00139,P27144,P60953,Q9BW19	21
Dna double strand break repair	0.3804748174461287	0.149081942791333	0.8814889742186645	1.0	1.0	63	P35251,Q9UGN5,Q9UQ84,Q9BX63,Q5UIP0,P49916,Q6ZW49,Q92547,P60510,Q13472,P61088,Q92889,P15927,P40938,Q92878,P41440,Q14676,P28340,O00213,Q13535,P51530,O14757,Q9NXR7,Q07864,Q04323,P35244,P38398,P09874,P12004,O60264,O60921	31
Interleukin 1 signaling	0.3722965976281152	0.148938111560225	0.8816024679106842	1.0	1.0	50	O15111,P25787,P49721,Q02750,P51665,Q92530,P20618,P09429,O43318,P28070,O75832,P61088,Q99436,Q9H0E2	14
Response of eif2ak4 gcn2 to amino acid deficiency	0.3378465175391211	0.1483248336952896	0.8820864176683934	1.0	1.0	76	P62847,P46779,P62753,P61254,P18077,P61247,P62244,P08708,P84098,P42766,P62851,Q07020,P46782,P62917,P62913,P62263,P46777,Q9Y3U8,P05387,P40429,P62750,P18124,P62841,Q92616,P62899,P39023,P62910,P62829,P83881,P35268,P20042,P63173,P62424	33
Eukaryotic translation elongation	0.3195721895539932	0.1482327372278461	0.8821590966284398	1.0	1.0	77	P62847,P46779,P62753,P61254,P18077,P61247,P62244,P08708,P84098,P42766,P62851,Q07020,P46782,P62917,P62913,P62263,Q9Y3U8,P46777,P05387,P40429,P62750,P18124,P62841,P62899,P39023,P62910,P62829,P83881,P35268,P63173,P62424	31
Meiosis	0.3335959962348954	0.1481726135134139	0.8822065444672493	1.0	1.0	27	Q14683,Q9BTC0,Q92878,Q8WXH0,Q13472,P35244,P38398,Q13535,P27694,P11802,Q9UQE7,O94901,P15927,Q8N3U4,Q8NF91,O60216	16
Reproduction	0.3335959962348954	0.1481726135134139	0.8822065444672493	1.0	1.0	27	Q14683,Q9BTC0,Q92878,Q8WXH0,Q13472,P35244,P38398,Q13535,P27694,P11802,Q9UQE7,O94901,P15927,Q8N3U4,Q8NF91,O60216	16
Sumoylation of chromatin organization proteins	0.3570900742316255	0.1480062615117988	0.8823378266981932	1.0	1.0	40	O15504,P35658,Q12873,Q9HC52,P45973,O75928,Q9BVL2,Q14781,O75925	9
Apc c cdc20 mediated degradation of cyclin b	0.3006026997746136	0.1479418638687708	0.8823886491142932	1.0	1.0	12	Q9UJX6,Q16763,Q9H1A4,P14635	4
Degradation of beta catenin by the destruction complex	0.3724937407975023	0.1478424454715003	0.8824671107495112	1.0	1.0	52	P25787,P49721,Q14738,P49841,P51665,P20618,Q04727,P56545,Q13362,P28070,O75832,Q99436,P48729	13
Tp53 regulates transcription of dna repair genes	0.3478193215057297	0.1473066683067274	0.8828899693511163	1.0	1.0	35	Q14241,P19447,Q9H3P2,P55199,Q9NYV4,P38398,Q9NVI1,Q8WX92,Q13535,P13984,Q9BXW9,P24928,P23193,Q9Y5B9,P50750,Q08945,O14757,O00267	18
E2f mediated regulation of dna replication	0.2975113696135902	0.1469677451952812	0.8831574794278421	1.0	1.0	11	P49642	1
Stat5 activation	0.5937244201910002	0.1461195946758163	0.8838269781214514	1.0	1.0	2	P62993	1
Pi 3k cascade fgfr2	0.5937244201910002	0.1461195946758163	0.8838269781214514	1.0	1.0	2	P62993	1
Pi 3k cascade fgfr3	0.5937244201910002	0.1461195946758163	0.8838269781214514	1.0	1.0	2	P62993	1
Stat5 activation downstream of flt3 itd mutants	0.5937244201910002	0.1461195946758163	0.8838269781214514	1.0	1.0	2	P62993	1
Pi 3k cascade fgfr1	0.5937244201910002	0.1461195946758163	0.8838269781214514	1.0	1.0	2	P62993	1
Pd 1 signaling	0.5937244201910004	0.1461195946758163	0.8838269781214514	1.0	1.0	2	P41240	1
Pi 3k cascade fgfr4	0.5937244201910002	0.1461195946758163	0.8838269781214514	1.0	1.0	2	P62993	1
Pten regulation	0.3492881286008167	0.1461034277506182	0.8838397405024772	1.0	1.0	72	P25787,P25788,P27361,Q13200,Q9HC52,Q9UHA4,Q99460,O00232,Q92530,Q14839,O75832,O00308,P46934,Q9UNE7,P51665,Q8WXI9,Q93009,P28070,Q15382,P28482,P49721,P67870,P48556,P20618,Q15910,P19784,Q13547,Q15022,O95983,Q12873,O60341,Q86YP4,Q15008,Q14781,Q99436,Q06323	36
Formation of incision complex in gg ner	0.3124547311146184	0.1458171827824056	0.8840657109923753	1.0	1.0	18	Q86WJ1,Q9UGN5,P19447,Q13620,P61956,P35244,P09874,P27694,Q92889,P61088,P15927,O75925	12
Pi3k akt signaling in cancer	0.3055185480672921	0.1454909769250859	0.8843232393224538	1.0	1.0	15	O15111,P49841,P84095,O00459,P06241,Q9NWH9,O43815	7
Neddylation	0.2569868612692063	0.1449587588710273	0.8847434334387194	1.0	1.0	75	P25787,Q92530,O75832,Q15345,P51665,Q8NEZ5,P61962,P28070,Q9H9Q2,P49721,Q86VP6,P20618,Q8TBC4,Q13564,Q13309,Q13618,Q99627,Q15008,Q93034,Q96GG9,Q99436	21
Auf1 hnrnp d0 binds and destabilizes mrna	0.3556312093228483	0.1447545517752911	0.8849046666081233	1.0	1.0	42	P25787,P49721,Q04637,P51665,Q92530,P20618,P04792,P11940,O75832,P28070,Q99436	11
Dual incision in tc ner	0.3472547108303216	0.144121787786848	0.8854043001658247	1.0	1.0	37	P35251,Q9HCS7,P19447,P41440,Q13620,Q07864,P35244,P27694,P12004,P23193,O60306,Q92889,P24928,P28340,P15927,P40938	16
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s	0.363719464911287	0.1436492608575758	0.8857774394831002	1.0	1.0	51	P62847,Q9UBQ5,P62753,O15372,P11940,P61247,P55884,P62244,P56537,P08708,Q04637,P62851,P46782,P62263,P60228,P23588,O75821,P62277,P62841,P20042,O75822	21
Rho gtpases activate wasps and waves	0.3144297805426555	0.1432360869936478	0.8861037303529775	1.0	1.0	20	P28482,Q96F07,O15144,P62993,Q9NZQ3,Q9Y6W5,Q9UQB8,P61160,P60953,Q8WUW1	10
Tcf dependent signaling in response to wnt	0.3574790707724301	0.1430240317596349	0.8862712017072056	1.0	1.0	65	P25787,Q92530,O75832,P48729,P51665,Q13362,Q9UBL3,P28070,O14641,P49721,P67870,P20618,P19784,Q16537,Q14738,P49841,P51532,Q04727,Q13618,Q99436	20
Metabolism of water soluble vitamins and cofactors	0.3513571525546584	0.1427794175957307	0.8864643928974185	1.0	1.0	41	Q969G6,P49914,P41440,Q9NRN7,P35030,P05165,P34897,P50747,Q8NFF5,Q96CD2,P34896,P43490,O00763	13
Transcriptional regulation by runx1	0.3080923283046334	0.1419534066534092	0.8871168089935653	1.0	1.0	71	O14497,P25787,Q13200,Q9HC52,Q92530,Q96GM5,O75832,Q07157,O15047,P51665,Q9UBL3,P28070,Q00534,P49721,Q86U86,P67870,Q92925,P48556,P20618,Q68CP9,P19784,Q96ST3,P51532,Q15008,Q14781,Q96J02,Q99436	27
Asymmetric localization of pcp proteins	0.3442729610338539	0.1398357285951065	0.888789783289031	1.0	1.0	39	O14641,P25787,P49721,P51665,P20618,P28070,O75832,Q99436	8
Rab regulation of trafficking	0.3454982349141494	0.139768832122818	0.8888426398867448	1.0	1.0	40	Q9UJY4,Q9Y2L5,Q4KMP7	3
Beta catenin independent wnt signaling	0.3511544757928505	0.1393530633061241	0.8891711604350592	1.0	1.0	60	O14641,O95782,P25787,P49721,P09471,P60763,P51665,P20618,P63218,O43318,P28070,Q99436,P32121	13
Interferon signaling	0.2676265794784819	0.1387968039712838	0.889610719601929	1.0	1.0	69	P19474,O60573,O15504,P35658,P19525,P46934,Q04637,Q9BVL2,P61088,Q8TEM1,P49790,P38919,O43432,Q9Y3Z3,P19174,O15344,P29372,O75369,P78344,P52294,Q14258,P12270,O75925	23
Transport of mature transcript to cytoplasm	0.312701496714492	0.1385062941864406	0.8898402955208886	1.0	1.0	67	Q6UN15,Q9P2I0,O75152,Q9Y5S9,Q96QD9,Q05519,Q13243,O15504,P35658,P52298,Q9BVL2,Q10570,Q15287,Q9Y3Y2,Q8TEM1,P49790,P38919,Q16629,Q8IYB3,Q9BZI7,Q08170,P84103,Q9C0J8,P12270,Q92620	25
Fc epsilon receptor fceri signaling	0.3441385539956466	0.1381761502593577	0.8901012036104607	1.0	1.0	61	P25787,P25788,P27361,Q13200,Q99460,O00232,O00459,Q92530,Q13177,O14733,O43318,O75832,Q15750,P51665,P62993,P28070,P61088,P28482,O15111,P49721,P62333,P48556,P20618,P29353,P63208,P19174,O43865,Q15008,P06241,Q99436,Q06323	31
Mrna splicing minor pathway	0.3335410061334558	0.1373300438664293	0.8907699238341396	1.0	1.0	34	O75533,P52298,Q86XP3,Q16629,P67809,P13984,P24928	7
Clec7a dectin 1 signaling	0.3489806327314179	0.1369924992487808	0.8910367239471195	1.0	1.0	52	O15111,P25787,P49721,P51665,Q92530,P20618,Q8TBC4,O43318,P28070,O75832,P61088,Q99436,Q14790	13
Extracellular matrix organization	0.3295693716853332	0.1366633957515097	0.891296863956055	1.0	1.0	32	P17655,P20810,Q32P28,P12814,P07942,Q15149,P13674,O15460	8
Fcgr3a mediated il10 synthesis	0.2801421721957047	0.1366162676167003	0.8913341173700007	1.0	1.0	7	P10644,P06241,P19174	3
Cellular response to heat stress	0.1487228161696381	0.1362881644245332	0.8915934800026497	1.0	1.0	67	O15504,P35658,Q9BVL2,Q53FT3,Q99543,O75190,Q13535	7
Tnfr2 non canonical nf kb pathway	0.3420823024467901	0.1357887141164791	0.8919883132505049	1.0	1.0	43	O15111,P25787,P49721,P51665,P20618,Q8TBC4,P28070,Q99436	8
Glutathione conjugation	0.2967969161382541	0.1355686513067058	0.8921622892398595	1.0	1.0	15	O75223	1
Glucagon like peptide 1 glp1 regulates insulin secretion	0.3000947486995043	0.135487150991225	0.8922267226076461	1.0	1.0	6	P46940	1
Trna processing	0.2162316723984466	0.1352679020491473	0.8924000622489008	1.0	1.0	66	O15504,P35658,Q9UBP6,Q9BVL2,Q92499,Q52LJ0,P12270,P78346,Q96PZ0,Q9H974,Q969Y2,Q7Z4G4	12
Rac1 gtpase cycle	0.3442497224282052	0.1352015561047415	0.8924525167981399	1.0	1.0	51	Q07960,Q96F07,Q13177,Q9NSV4,Q86Y07,Q8WUW1,Q8N5V2,O94887,P46940,Q16513,Q96N67,Q14185,Q9Y2I1,Q9H8V3,Q13017,Q9UQB8,O00161,O15498,Q9Y4F1,Q96AC1,P60953	21
Cyclin a cdk2 associated events at s phase entry	0.3415631014253389	0.1350982772673817	0.8925341722335016	1.0	1.0	44	P25787,P49721,Q13309,P51665,P20618,Q5TKA1,P28070,O75832,Q99436	9
Degradation of dvl	0.3349071913648142	0.1339648120808106	0.893430399460871	1.0	1.0	39	O14641,P25787,P25788,Q13200,P49721,P51665,O00232,Q92530,P48556,P20618,Q13618,P28070,O75832,Q15008,Q99436,Q06323	16
Regulation of mrna stability by proteins that bind au rich elements	0.2688176436969569	0.1337072109536463	0.893634102852968	1.0	1.0	64	Q99436,P25787,P49721,P35658,Q13868,Q04637,P51665,Q92530,Q8IZH2,P20618,P04792,P11940,O75832,P28070,P39687,Q9Y2L1	16
Fceri mediated nf kb activation	0.3394887361839099	0.1334422611884919	0.8938436246510315	1.0	1.0	47	O15111,P25787,P49721,P51665,Q92530,P20618,O43318,P28070,O75832,P61088,Q99436	11
Pcp ce pathway	0.3378564996154509	0.1334340226403726	0.8938501397989054	1.0	1.0	53	O14641,O95782,P25787,P49721,P60763,P20618,P28070,Q99436,P32121	9
Regulation of runx2 expression and activity	0.3371783223974656	0.1332703689067802	0.8939795607213827	1.0	1.0	43	P25787,P25788,Q13200,Q99460,O00232,Q92530,P42224,O75832,Q9UNE7,P51665,P28070,P49721,P62333,P48556,P20618,P49841,Q13309,Q15008,Q99436,Q06323	20
Dna replication pre initiation	0.2350635941003082	0.133236404467805	0.8940064208902911	1.0	1.0	64	P25787,P25788,Q13200,P49643,Q99460,O00232,Q92530,P27694,O75832,P51665,O43913,P49642,Q7L590,P33991,P28070,P25205,P15927,P49721,O00311,P48556,P20618,O60684,Q07864,P52294,P35244,Q15008,Q99436,Q06323	28
Tbc rabgaps	0.2943242235492792	0.1329587665067144	0.8942259904597183	1.0	1.0	15	Q9UJY4,Q9Y3P9,Q9UJ41,Q4KMP7	4
Nucleotide excision repair	0.271435288792536	0.132769176893254	0.894375931782392	1.0	1.0	63	P18858,P35251,Q9UGN5,P19447,Q9H981,O60306,P49916,P61088,Q9H9Q2,P41440,P55199,P24928,P28340,Q86WJ1,Q07864,P09874,P23193,Q99627,Q9HCS7,O75925	20
Signaling by hedgehog	0.2683658082833453	0.1326869905302134	0.8944409319379782	1.0	1.0	63	P25787,P49721,P32121,P49841,P51665,P20618,P28070,O75832,P04350,Q99436,P48729,Q9Y496,O75386	13
Post chaperonin tubulin folding pathway	0.2835188106315336	0.132667824343676	0.8944560903345671	1.0	1.0	10	P04350,O75347,Q9BUF5,Q15813	4
Tcr signaling	0.3351266440267038	0.1321240956012991	0.8948861374516532	1.0	1.0	51	O15111,P25787,P49721,P51665,P20618,Q8N8S7,O43318,P28070,P61088,P19174,Q99436	11
Budding and maturation of hiv virion	0.284463894967186	0.1313304202850306	0.8955139282845552	1.0	1.0	11	O75351,Q99816,Q9UQN3,Q8WUM4,Q9NZZ3,Q96FZ7,Q9H444,Q8WUX9,Q9UN37,Q9H9H4	10
Mhc class ii antigen presentation	0.3075769047497808	0.131249976733239	0.8955775621502085	1.0	1.0	59	O95487,P56377,O94855,O15020,O94979,O95486,P52907,Q9H0B6,Q9BXS5,Q9Y496,Q9NSK0,Q96FJ2	12
Signaling by mras complex mutants	0.3633633633633681	0.1312335818269753	0.8955905312182126	1.0	1.0	4	P10398,P31946,Q9UQ13	3
Mitotic prophase	0.2299838477006601	0.1310996509384354	0.8956964772908267	1.0	1.0	62	O15504,P35658,Q14980,P53350,Q9BVL2,Q99986,P12270,Q86Y07,P14635,Q9NTJ3	10
Dectin 1 mediated noncanonical nf kb signaling	0.3318825689934556	0.1307709434267307	0.8959565093557613	1.0	1.0	43	O15111,P25787,P49721,P51665,P20618,Q8TBC4,P28070,Q99436	8
C type lectin receptors clrs	0.309030217316961	0.130623253288411	0.8960733468696866	1.0	1.0	58	P25787,P25788,Q13200,Q99460,O00232,Q92530,Q13177,O43318,O75832,Q15750,P51665,P28070,P61088,Q14790,O15111,P49721,P62333,P48556,P20618,Q8TBC4,P63208,Q05655,O43865,Q15008,P06241,Q99436,Q06323	27
The role of gtse1 in g2 m progression after g2 checkpoint	0.3308444162160919	0.1305854014344088	0.896103291794764	1.0	1.0	50	Q99436,P25787,P49721,P53350,P51665,P20618,P28070,O75832,P04350,P14635	10
Synthesis of pyrophosphates in the cytosol	0.5844474761255162	0.1305850623297779	0.8961035600640035	1.0	1.0	2	Q13572	1
Chromosome maintenance	0.3313147526089602	0.1305218153608511	0.8961535956139315	1.0	1.0	49	P18858,P35251,Q5H9R7,Q9H3R5,Q9BUR4,Q9UER7,Q96T23,P49642,Q9NPE3,P15927,P40938,P41440,P24928,O60832,P28340,P51530,Q8WVB6,P35244,Q71F23,P12004,O60264	21
Hedgehog off state	0.3235231135914775	0.1302880683728051	0.8963385196645166	1.0	1.0	54	P25787,P25788,Q13200,Q99460,O00232,Q92530,O75832,P48729,Q8NCM8,O75386,Q9BUF5,P51665,P28070,Q9Y496,P49721,P62333,P48556,P20618,P04350,P10644,P49841,Q15008,Q96J02,Q99436,Q06323	25
Degradation of axin	0.3264069231246266	0.1302800711333255	0.8963448466132988	1.0	1.0	37	P25787,P49721,P51665,P20618,P28070,O75832,Q99436	7
Apc c mediated degradation of cell cycle proteins	0.3000175775032419	0.1296876299369125	0.8968135697905586	1.0	1.0	58	Q9UJX6,P25787,P49721,Q13309,P53350,P51665,Q92530,P20618,O14965,Q9H1A4,Q16763,P28070,O75832,P14635,Q99436	15
Diseases of programmed cell death	0.3153433814591838	0.1295591391541992	0.896915232921293	1.0	1.0	29	P20810,P17655,P49642,Q15910,P42771,Q14790	6
Aggrephagy	0.2927450791917954	0.1293742388008665	0.8970615308110013	1.0	1.0	16	Q9Y6G9,Q96FJ2,P61088	3
Switching of origins to a post replicative state	0.2123725593210425	0.1289002244472711	0.8974365990683251	1.0	1.0	60	Q9UJX6,P25787,P25788,Q9UJX4,Q13200,Q99460,O00232,Q92530,Q16763,O75832,P51665,O43913,P33991,P28070,P25205,P49721,P62333,P48556,P20618,Q13309,Q9H1A4,Q15008,Q99436,Q06323	24
Regulation of hsf1 mediated heat shock response	0.1635603488493172	0.1288318289208309	0.8974907195574104	1.0	1.0	60	O15504,P35658,Q9BVL2,Q53FT3,Q99543,O75190,Q13535	7
Defective intrinsic pathway for apoptosis	0.2940310298579399	0.1287660152951543	0.8975427974722812	1.0	1.0	17	P17655,P42771,P20810	3
Rrna modification in the nucleus and cytosol	0.2668139466157829	0.1286511800373946	0.8976336669581062	1.0	1.0	59	P62753,Q8TED0,Q96EU6,Q9UNQ2,Q9NV31,Q68CQ4,O15213,Q14690,P46087,Q13601,P62263,Q14692,Q9NPE3,Q9BVI4,Q9BVJ6,Q9H6R4,Q8IY37,Q8IWA0,Q9Y6V7,O43818,Q9Y2R4,Q9Y2X3,O60832,Q9H0A0,Q9NRX1,O43709,P78316,Q9H0S4	28
Rna polymerase ii transcription termination	0.3257742580319521	0.1285760359464905	0.8976931294306172	1.0	1.0	48	Q6UN15,Q9P2I0,O75152,P51003,Q9Y5S9,Q96QD9,Q05519,Q13243,P52298,Q10570,Q15287,Q9Y3Y2,Q16629,Q8IYB3,Q9BZI7,Q08170,P84103,Q9C0J8,Q92620	19
Negative regulation of notch4 signaling	0.3226481307616342	0.1272383864156485	0.8987517243054624	1.0	1.0	40	P25787,Q9Y6A5,P49721,P51665,P20618,P28070,O75832,Q99436	8
Transcriptional regulation by runx2	0.3081636282729607	0.1262750938205015	0.8995141706792118	1.0	1.0	52	P25787,P25788,P27361,Q13200,Q99460,O00232,Q92530,P42224,P11802,O75832,P06493,Q9UNE7,P51665,P28070,P28482,P49721,P62333,P48556,P20618,P49841,Q13309,Q96PK6,Q15008,P14635,Q99436,Q06323	26
Regulation of ras by gaps	0.3200371766014719	0.1262726210903206	0.8995161279655262	1.0	1.0	39	P25787,P25788,Q13200,P49721,P51665,O00232,Q92530,P48556,P20618,Q13618,P28070,O75832,Q15008,Q99436,Q06323	15
Scf skp2 mediated degradation of p27 p21	0.3204853345233291	0.126156652948908	0.8996079230811864	1.0	1.0	41	P25787,P25788,Q13200,P49721,Q13309,Q99460,O00232,P51665,Q92530,P62333,P48556,P20618,P11802,P28070,O75832,Q15008,Q99436,Q06323	18
Antigen processing cross presentation	0.2748359614275493	0.1261036796493151	0.8996498547870164	1.0	1.0	56	O15111,P25787,Q9UIQ6,P49721,P51665,P20618,P09429,P28070,O75832,Q99436,O00161,Q9UBG0	12
Autophagy	0.2420420511785341	0.126029696999394	0.8997084171867205	1.0	1.0	57	Q99816,P67870,Q9Y6G9,P54646,P19784,P50542,P61088,Q15382,Q676U5,Q9H9H4,Q96FJ2,Q9NT62	12
Signaling by the b cell receptor bcr	0.3076784995682884	0.1255752529228616	0.9000681531653345	1.0	1.0	51	P25787,P25788,Q13200,Q99460,O00232,Q92530,O43318,O75832,Q13586,P51665,P62993,P62942,P28070,O15111,P49721,P62333,P48556,P20618,O43865,Q15008,P06241,Q99436,Q06323	23
Stabilization of p53	0.3177076742516428	0.1251033639073578	0.9004417202085595	1.0	1.0	40	P25787,P49721,P51665,P20618,P28070,Q99436,P42771	7
Hcmv infection	0.2182453331472338	0.12471665253675	0.900747873518246	1.0	1.0	56	Q99816,O15504,P35658,Q9Y6G9,Q9UER7,Q9BVL2,Q9HD42,P12270,Q15910,Q9H9H4,Q96FJ2	11
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.3030319369080625	0.1241598190100994	0.9011887357899804	1.0	1.0	50	Q9UJX6,P25787,P49721,Q13309,P53350,P51665,Q92530,P20618,O14965,Q9H1A4,P28070,O75832,Q99436	13
Metabolism of polyamines	0.3142225581631235	0.1237585523714659	0.9015064498644654	1.0	1.0	39	Q99436,P25787,P25788,Q13200,P49721,P51665,O00232,Q92530,P48556,P20618,P28070,O75832,Q15008,P19623,Q06323	15
Estrogen dependent gene expression	0.3075279001589205	0.1230149245046558	0.9020952796845976	1.0	1.0	31	P50750,Q15185,Q14683,O60341,Q8N3U4,P13984,P24928,Q15648,O14646,O60216	10
Apoptotic execution phase	0.3077016490151029	0.1225909572972869	0.9024310154607018	1.0	1.0	32	P15924,P26583,Q13464,P09429,Q15149,O76075,Q14790,Q07157	8
Sumoylation of dna damage response and repair proteins	0.288976645136082	0.1221379397748671	0.9027897752002862	1.0	1.0	50	O15504,P35658,Q9HC52,O75928,Q9BVL2,P09874,Q14781,P42771,Q96MG7,O75925	10
Antiviral mechanism by ifn stimulated genes	0.2405739576783839	0.1219195749599388	0.9029627127013452	1.0	1.0	53	O60573,O15504,P35658,P19525,P46934,Q04637,Q9BVL2,P61088,Q8TEM1,P49790,P38919,Q96EE3,O43432,P19174,O75369,P78344,P52294,P21333,P12270,Q14258	20
Cation coupled chloride cotransporters	0.578990450204643	0.1219102831079088	0.9029700716340752	1.0	1.0	2	P55011	1
Mapk6 mapk4 signaling	0.2917811589211894	0.1217674038526702	0.9030832297616108	1.0	1.0	49	P25787,P25788,Q13200,Q99460,O00232,Q16512,Q92530,Q13177,P04792,O75832,P06493,P25685,Q9HCE1,P51665,P35998,P28070,O14980,P49721,P62333,P48556,P20618,O00233,Q15008,Q99436,P62191,P60953,Q06323	27
Downstream signaling events of b cell receptor bcr	0.3016866270736825	0.1216394945798	0.9031845335682882	1.0	1.0	46	O15111,P25787,P49721,P51665,P20618,O43318,P28070,Q99436	8
G1 s dna damage checkpoints	0.3057607618075549	0.1210966429820989	0.9036144881215632	1.0	1.0	42	P25787,P49721,P51665,Q92530,P20618,P28070,O75832,Q99436,P42771	9
Rab gefs exchange gtp for gdp on rabs	0.3033774084153227	0.1203559702024911	0.904201168481018	1.0	1.0	32	Q9Y2L5	1
Uch proteinases	0.2784835723766798	0.1202007953763235	0.9043240877258596	1.0	1.0	49	P49721,P25787,P51665,P20618,Q9H981,P28070,Q99436	7
Transcription coupled nucleotide excision repair tc ner	0.2628448012188887	0.1198572379935816	0.9045962393386312	1.0	1.0	50	P18858,P35251,P19447,Q13620,O60306,P49916,Q92889,P15927,Q9H9Q2,P41440,P55199,P24928,P28340,Q07864,P35244,P12004,P23193,Q99627,Q9HCS7	19
Sealing of the nuclear envelope ne by escrt iii	0.2749658002736053	0.1198166493412861	0.9046283926913274	1.0	1.0	12	Q9BUF5,Q8NC56,Q9UQN3,Q9H444,Q96FZ7,P04350,Q9BVA1,Q8WUX9,Q9UN37,P68371,Q13885	11
Nuclear envelope ne reassembly	0.2207327662298067	0.1195249937053023	0.9048594398566556	1.0	1.0	51	Q9BVL2,Q86Y07,P14635	3
Resolution of abasic sites ap sites	0.2975727315402835	0.1190884331643362	0.9052052945258624	1.0	1.0	28	P18858,P29372,P35251,Q9UGN5,Q07864,Q96T60,P41440,P35244,P09874,P12004,P28340,P15927,P49916,P27695	14
Orc1 removal from chromatin	0.2439681274058888	0.119008711154682	0.9052684543288272	1.0	1.0	50	P25787,P25788,Q13200,Q99460,O00232,Q92530,O75832,P51665,O43913,P33991,P28070,P25205,P49721,P62333,P48556,P20618,Q13309,Q15008,Q99436,Q06323	20
Transcriptional regulation by runx3	0.2948271730591298	0.1186850211011964	0.905524904091178	1.0	1.0	43	P25787,P49721,P51665,Q92530,P20618,P28070,O75832,Q99436,P42771	9
Global genome nucleotide excision repair gg ner	0.2653698696709637	0.1173468278721952	0.9065852180609204	1.0	1.0	47	P18858,P35251,Q9UGN5,P19447,Q13620,Q9H981,P49916,P61088,Q92889,P15927,Q9H9Q2,P41440,P28340,Q86WJ1,Q07864,P35244,P09874,P12004,Q99627,O75925	20
Regulation of hmox1 expression and activity	0.2310196267528548	0.1166427175808319	0.9071431850193332	1.0	1.0	48	P25787,P49721,Q13309,P67870,P51665,P20618,P19784,Q9BX63,P28070,O75832,Q99436	11
Esr mediated signaling	0.2302143365214898	0.1166231090157881	0.9071587243378724	1.0	1.0	48	P28482,Q15185,Q14683,O60341,Q8N3U4,O14646,O00459,P63218,P29353,P13984,P04792,Q9UQE7,P24928,Q15648,Q13547,P50750,O60216,O43815	18
Signaling by notch4	0.2734502986127841	0.1164826002729656	0.9072700751932896	1.0	1.0	45	P25787,Q9Y6A5,P49721,P51665,Q92530,P20618,P28070,O75832,Q99436	9
Regulated necrosis	0.2837410031250408	0.1164206714564135	0.9073191533352016	1.0	1.0	20	P41440,P09429	2
Cellular senescence	0.216179401233872	0.1163608566006904	0.9073665565142888	1.0	1.0	48	P17096,Q9HC52,Q9Y6J0	3
Nuclear envelope breakdown	0.2850575606396233	0.1161729007257429	0.9075155133960512	1.0	1.0	42	O15504,P35658,P53350,Q9BVL2,Q99986,Q86Y07,P14635	7
Sumoylation of ubiquitinylation proteins	0.2927983543517614	0.1158813490756113	0.9077465773835944	1.0	1.0	30	O15504,P35658,O75928,Q9BVL2,O75925	5
Myd88 independent tlr4 cascade	0.2893862737428112	0.115617406375065	0.9079557671308036	1.0	1.0	26	O15111,Q14738,Q02750,Q9UHD2,O14733,O43318,P09429,P61088,Q6SZW1,Q14790	10
Cdc42 gtpase cycle	0.2886399711555762	0.1154742273285988	0.9080692474189224	1.0	1.0	39	Q8N5V2,P14923,Q07960,P46940,Q9Y4F1,Q9NSV4,Q13017,Q9UQB8,Q9Y597	9
L1cam interactions	0.2630654796629268	0.1154393717398331	0.9080968734090712	1.0	1.0	45	O95782,P15311,O15020,Q02750,P67870,A0MZ66,P19784,Q96S59,P35241,P07942	10
Platelet homeostasis	0.2732303966349876	0.1153621391797378	0.9081580871145962	1.0	1.0	14	Q13362,Q13586,P63218	3
Degradation of gli1 by the proteasome	0.2832443293536851	0.1152634324150906	0.9082363218401066	1.0	1.0	41	Q99436,P25787,P25788,Q13200,P49721,Q99460,O00232,P51665,Q92530,P62333,P48556,P20618,P28070,O75832,Q15008,Q96J02,Q06323	17
Gpvi mediated activation cascade	0.262339224789022	0.1150406229333751	0.9084129233282549	1.0	1.0	8	P60953,P06241,P84095	3
Traf6 mediated nf kb activation	0.2614078687648311	0.1141872500353068	0.9090893587967748	1.0	1.0	8	P09429	1
Dna strand elongation	0.287021894747048	0.1133620525638189	0.9097435233961432	1.0	1.0	30	P18858,P49643,P35251,P51530,Q9BRX5,P49736,P49005,P41440,P35244,P49642,P27694,P12004,Q9Y248,P33991,P25205,P28340,P15927,P40938	18
Selective autophagy	0.2846511553227772	0.1127960345919401	0.9101922622176783	1.0	1.0	34	Q96FJ2,P54646,P50542,P61088	4
Rhobtb2 gtpase cycle	0.2779994567129935	0.1126739589151791	0.9102890475261464	1.0	1.0	20	O43396,P12814,Q9NYL9,Q8IYB3	4
Signaling by scf kit	0.2663956792530583	0.1125224343831435	0.9104091826340868	1.0	1.0	12	P63000,O00459,P62993,P42224,Q06124,P40763,P06241,O14757	8
Cellular response to hypoxia	0.2580490483996554	0.1124692922182595	0.910451316492966	1.0	1.0	42	P25787,P49721,P51665,P20618,P28070,Q99436	6
Defective cftr causes cystic fibrosis	0.1975289073857378	0.1119909712032245	0.91083056547094	1.0	1.0	44	P25787,P49721,P20618,P28070,Q99436,O94905	6
Rnd3 gtpase cycle	0.2750258006401742	0.1115648273651413	0.9111684615628588	1.0	1.0	19	P15924	1
Hedgehog ligand biogenesis	0.2261146287463367	0.1115105906698407	0.9112114678376916	1.0	1.0	43	P25787,P49721,P51665,P20618,P28070,Q99436	6
Runx1 regulates transcription of genes involved in differentiation of hscs	0.2525724046602009	0.1111340065615687	0.911510082423692	1.0	1.0	41	P25787,P49721,P51665,P20618,P28070,Q99436	6
Cdt1 association with the cdc6 orc origin complex	0.2582565492210963	0.1108744144616661	0.9117159347871826	1.0	1.0	40	P25787,P49721,P51665,P20618,P28070,Q99436	6
Mitochondrial trna aminoacylation	0.2730227134604684	0.1103373653389909	0.9121418249036736	1.0	1.0	19	Q96GW9,Q15046,Q5T160,P49590,P26640,Q9Y2Z4	6
Base excision repair	0.2752549030682682	0.1092301626714264	0.9130199370841076	1.0	1.0	31	P18858,P29372,P35251,Q9UGN5,Q07864,Q96T60,P41440,P35244,P09874,P12004,P28340,P15927,P49916,P27695	14
Cooperation of pdcl phlp1 and tric cct in g protein beta folding	0.2631208984648026	0.1089061436914557	0.9132769336715176	1.0	1.0	13	P63218,P67870	2
Myogenesis	0.2523745308038448	0.1078683075313897	0.914100157324429	1.0	1.0	7	O60271,P35221	2
Rmts methylate histone arginines	0.2703820455143579	0.1078121288748434	0.9141447215223252	1.0	1.0	21	O14497,Q86U86,Q92925,P51532,Q68CP9,Q96GM5,P11802	7
Synthesis of ip3 and ip4 in the cytosol	0.3469303829720954	0.1070212630351134	0.914772111168744	1.0	1.0	4	Q01968,P19174	2
Cytosolic trna aminoacylation	0.2696051393062957	0.1068638565785506	0.9148969872188292	1.0	1.0	23	P26639,Q13155,P07814,Q15046,P14868,P26640,P41250,P54577,O43324,P49591,P49588	11
Trna aminoacylation	0.2271419908619853	0.1067141234455094	0.9150157777023616	1.0	1.0	38	Q96GW9,Q13155,P26639,P07814,Q15031,Q15046,P14868,P26640,Q5T160,P49590,P54577,P41250,O43324,P49591,P49588,Q9Y2Z4	16
Signaling by braf and raf1 fusions	0.2684124991307181	0.1062016953445302	0.9154223258651852	1.0	1.0	26	Q02750,P46940,Q96PU8,P51114,O15164,P41240,O00203,O43252,Q9Y490,P18206,P32121,P36507	12
Hcmv late events	0.2014591860933146	0.1058547185676056	0.9156976214858384	1.0	1.0	38	Q99816,O15504,P35658,Q9BVL2,Q9HD42,P12270	6
Transcriptional regulation by small rnas	0.1934962962948991	0.1057190421515565	0.9158052715663304	1.0	1.0	38	O15504,P35658,Q9BVL2,O15397,P12270	5
Transport of mature mrnas derived from intronless transcripts	0.1915365111582656	0.1056920203947811	0.9158267116913146	1.0	1.0	38	O15504,P35658,Q6UN15,Q9P2I0,P52298,Q9BVL2,Q9C0J8,Q10570,P12270,Q8TEM1,P49790	11
Sumoylation of rna binding proteins	0.2449084890041417	0.10547143458785	0.9160017354381692	1.0	1.0	35	O15504,P35658,Q9HC52,Q9BVL2,Q14781	5
Fcgamma receptor fcgr dependent phagocytosis	0.2292227201161669	0.1049806235073522	0.9163911839506488	1.0	1.0	36	P28482,Q14185,P35579,P60953,P46108,O00459,Q96F07,P62993,O15144,Q9NZQ3,Q9Y6W5,O43865,P06241,P19174,Q9UQB8,P61160,Q05655,Q8WUW1	18
Viral messenger rna synthesis	0.1955115788963025	0.1037004068648248	0.9174071037656908	1.0	1.0	36	O15504,P35658,Q9BVL2,P12270,P13984	5
Eph ephrin signaling	0.1784012282856926	0.1034699750311216	0.9175899780207192	1.0	1.0	36	Q8N5V2,O95782,P35579,Q13464,O15144,Q00610,Q13177,P06241,O75116,P61160,P60953	11
Sumoylation of dna replication proteins	0.2132852764460791	0.1032153570900798	0.9177920518137196	1.0	1.0	35	O15504,P35658,Q96EE3,Q9BVL2,Q02880,O14965,P12270,Q53HL2,P12004,Q8TEM1,P46060,P49790,P11388	13
Ksrp khsrp binds and destabilizes mrna	0.2532327465328496	0.1031601284001873	0.9178358839544448	1.0	1.0	12	Q9Y2L1,Q13868,Q06265	3
Toll like receptor cascades	0.2430795517308651	0.1029753279864429	0.9179825522531522	1.0	1.0	32	O15111,Q14738,Q02750,Q9UHD2,Q15075,O14733,O43318,P09429,P61088,Q6SZW1,Q14790	11
Branched chain amino acid catabolism	0.2570297391494416	0.1029498639070354	0.9180027622385248	1.0	1.0	16	O14874	1
Cargo trafficking to the periciliary membrane	0.2563789956502469	0.1017163195792456	0.9189818481820232	1.0	1.0	19	Q96A65,Q8IYI6,Q8TAG9	3
Tryptophan catabolism	0.5648021828103731	0.1009510363581275	0.9195893288515824	1.0	1.0	2	P08195	1
Oncogenic mapk signaling	0.2253065381074085	0.1002766352532836	0.9201247063494506	1.0	1.0	31	Q02750,P46940,Q96PU8,P51114,O15164,P41240,O00203,O43252,Q9Y490,P18206,P32121,P36507	12
Nuclear pore complex npc disassembly	0.22662902937218	0.0995557940509974	0.920696990633207	1.0	1.0	30	Q9BVL2,O15504,P35658,P14635	4
Integration of energy metabolism	0.2461998221477737	0.0989403865163256	0.9211856024025222	1.0	1.0	24	Q14738,P46940,P63218,P54646,O00763	5
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand	0.1803058804714347	0.0983152695057153	0.921681953610221	1.0	1.0	31	Q15185,P61163,Q9BUF5,P52907,Q9Y6G9,Q02790,P31689,P04350,Q14203,Q9UJW0,P31948,Q96FJ2	12
Formation of the early elongation complex	0.2468789912496144	0.0979320033433851	0.9219862871304104	1.0	1.0	19	P19447,P52298,P13984,O00267	4
Formation of tc ner pre incision complex	0.2135670448648207	0.0976222608551491	0.9222322473290704	1.0	1.0	29	P19447,P23193,P24928,O60306,Q9HCS7,Q9H9Q2	6
Processing of intronless pre mrnas	0.2457600871504162	0.0975498416173573	0.922289755043793	1.0	1.0	16	Q6UN15,Q9P2I0,P52298,Q9C0J8,Q10570,Q12996,P51003,Q86U42,Q8N684	9
Tysnd1 cleaves peroxisomal proteins	0.2666949204555988	0.0975074839344892	0.922323391232948	1.0	1.0	6	Q15067	1
Copi independent golgi to er retrograde traffic	0.2177508143511239	0.097070541081399	0.92267037516692	1.0	1.0	28	Q9NP72,Q9BUF5,P52907,Q9Y6G9,Q15042,Q9H2M9,P04350,P68402,Q14203,Q9UJW0,Q96FJ2	11
Darpp 32 events	0.2396644319683627	0.096954318105098	0.922762672338435	1.0	1.0	9	P62136	1
Interleukin 12 family signaling	0.1657516436990971	0.0960570317033386	0.9234752771754904	1.0	1.0	29	P52907	1
Ddx58 ifih1 mediated induction of interferon alpha beta	0.2382199155364926	0.0957523313035733	0.923717277432346	1.0	1.0	21	Q9UHD2,P09429,Q14790	3
Rhoj gtpase cycle	0.2246827285811454	0.0954452444326885	0.9239611802247072	1.0	1.0	25	P14923,Q07960,Q01968,Q9NSV4,Q13017,O00308	6
Sensory perception	0.1838119880187009	0.0953383098703088	0.924046114347679	1.0	1.0	28	P15311,P35579,P56545,P52907	4
B wich complex positively regulates rrna expression	0.2349086561609559	0.0941611384006173	0.9249811546340164	1.0	1.0	19	Q9UIG0,O75533,P62805,P49841,Q9NY93,Q9NR30,O60264,Q9BQG0,P19388,O00159	10
Signaling by fgfr	0.1690446731123403	0.0940279639170165	0.9250869431458306	1.0	1.0	27	P52298,P13984,P24928,P19174	4
Signaling by fgfr2	0.1690446731123402	0.0940279639170165	0.9250869431458306	1.0	1.0	27	P52298,P13984,P24928,P19174	4
Interleukin 12 signaling	0.192714481481319	0.093669797038756	0.9253714632323792	1.0	1.0	26	P52907	1
Listeria monocytogenes entry into host cells	0.2324990439995599	0.0930401981723485	0.9258716261846154	1.0	1.0	9	P62993,O60716,O75886,O14964,Q9NWH9	5
Gene and protein expression by jak stat signaling after interleukin 12 stimulation	0.2018757217307792	0.0923335844813257	0.926433005774472	1.0	1.0	24	P52907	1
Attenuation phase	0.2312179224148564	0.0918374663560498	0.9268271759837912	1.0	1.0	13	Q15185,Q02790,P04792,Q92598,O75190,Q00613	6
Activation of atr in response to replication stress	0.197956002540405	0.09116409757757	0.9273622021067792	1.0	1.0	23	O00311,O43913,P35244,Q13535,Q7L590,P33991,P15927,O60921,P40938,O14757	10
Erythropoietin activates ras	0.2990245309966073	0.0903177731815872	0.9280346969154364	1.0	1.0	5	P29353	1
Meiotic recombination	0.226724233226209	0.0902182362440453	0.928113792993968	1.0	1.0	13	Q92878,Q13472,P35244,P38398,P27694,P15927	6
Smooth muscle contraction	0.2259849760703738	0.0898484557494769	0.9284076417535174	1.0	1.0	12	P18206,P04083,Q9Y490,Q13177	4
Tp53 regulates transcription of cell cycle genes	0.2115690546428191	0.0893562919220429	0.9287987584564016	1.0	1.0	19	O14965,Q9C0C2,P14635,O75175,P06493	5
Erks are inactivated	0.2230625855550881	0.0890260020798351	0.9290612454916248	1.0	1.0	7	P28482,Q14738,P27361,P30154	4
Signaling by erbb2	0.2168602181498925	0.0885016095553179	0.9294780051204226	1.0	1.0	16	Q9UNE7,P29353,P06241,Q93034,P19174,Q05655,O60610	7
Ephb mediated forward signaling	0.2067041393665331	0.087258505348659	0.9304660361008998	1.0	1.0	17	Q13464,P06241,O75116,P61160,P60953	5
Vegfr2 mediated vascular permeability	0.2188994984042385	0.0871313789779485	0.9305670834090204	1.0	1.0	10	P14923,P35221	2
Aberrant regulation of mitotic exit in cancer due to rb1 defects	0.2130157697651383	0.0854880122103882	0.9318734254528712	1.0	1.0	11	Q9UJX6,Q9H1A4,Q13309	3
Transcriptional regulation by ventx	0.1889091113436908	0.0852014170514113	0.932101264035622	1.0	1.0	17	Q9UJX6,P42771,Q9H1A4,Q9H9B1	4
Hsf1 dependent transactivation	0.1666551141584031	0.0829211167278656	0.9339142631423684	1.0	1.0	16	Q15185,Q02790,P04792,Q92598,O75190	5
Negative regulators of ddx58 ifih1 signaling	0.2027813168413683	0.0824652538072272	0.9342767476402792	1.0	1.0	10	Q9UHD2,Q9UII4,Q7Z434,Q14258,Q96J02,P61086	6
Regulation of ifng signaling	0.2891489018077672	0.081764162447242	0.93483425484192	1.0	1.0	5	Q06124,O75925,P42224	3
Trafficking of glur2 containing ampa receptors	0.2033558414744258	0.0815077230887861	0.9350381831800476	1.0	1.0	7	P63010,O95782,P46459,Q96CW1	4
Negative regulation of met activity	0.1900912422546777	0.0799776607644565	0.9362550231729828	1.0	1.0	10	Q9NWH9,P17706,O14964,P62993	4
Interleukin 2 family signaling	0.2429116936155727	0.0799393896001656	0.9362854616861308	1.0	1.0	6	P29353,O00459,P42224	3
Dna methylation	0.3196833196833083	0.0750221579917748	0.9401970820431158	1.0	1.0	4	P26358,P62805,P16104	3
Shc1 events in erbb2 signaling	0.2782963974842899	0.0736645753153538	0.9412772869776316	1.0	1.0	5	P29353,Q05655	2
G beta gamma signalling through cdc42	0.3149108301127251	0.070409926693826	0.9438673905000892	1.0	1.0	4	P63218	1
Vegfr2 mediated cell proliferation	0.2666893031010807	0.0663960939199579	0.9470624799429944	1.0	1.0	5	Q05655,P19174	2
Pre notch processing in the endoplasmic reticulum	0.5350613915416151	0.0643025345560962	0.9487293353497784	1.0	1.0	2	Q04721	1
Signaling by leptin	0.5230559345156944	0.0521724484111959	0.95839128600867	1.0	1.0	2	Q06124	1
Interleukin 9 signaling	0.5230559345156944	0.0521724484111959	0.95839128600867	1.0	1.0	2	P42224	1
Interleukin 21 signaling	0.5230559345156944	0.0521724484111959	0.95839128600867	1.0	1.0	2	P42224	1
Activated ntrk2 signals through fyn	0.5004092769440711	0.0331250967611164	0.9735748294076771	1.0	1.0	2	P06241	1
Ntrk2 activates rac1	0.5004092769440711	0.0331250967611164	0.9735748294076771	1.0	1.0	2	P06241	1
Negative regulation of flt3	0.4995907230559402	0.0325249775425226	0.974053397365759	1.0	1.0	2	P41240	1