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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +7 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/basic/plot_1.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +8 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/basic/plot_3.png +3 -0
- interpro_conserved_site/basic/plot_4.png +3 -0
- interpro_conserved_site/basic/plot_5.png +3 -0
- interpro_conserved_site/basic/plot_6.png +3 -0
- interpro_conserved_site/basic/plot_7.png +3 -0
- interpro_conserved_site/basic/plot_8.png +3 -0
- interpro_conserved_site/basic/plot_9.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +1 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +47 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_14.png +3 -0
- interpro_domain/basic/plot_15.png +3 -0
- interpro_domain/basic/plot_16.png +3 -0
- interpro_domain/basic/plot_17.png +3 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
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interpro_active_site/basic/plot_0.png
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Git LFS Details
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:0f7d3d6267af54d018fe169fce396f47f0c3b508caf8d08e4bb6e85d228f1821
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3686,
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"annotations_size": 57,
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"title": "Average number of proteins per term",
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"value": 2.8421052631578947
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C114/C114_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine/threonine-protein kinase, active site [IPR008271] 0.3676186833926183 1.3976781859104406 0.1622097277608096 0.9999584364281916 0.3081984827455384 55 Q9H4A3,O43683,P49841,P19784,Q13177,P11802,P06493,Q14012,Q9H2G2,Q02750,P53350,O14757,Q9NYV4,P27361,P78362,Q13464,O14976,O00311,Q05655,Q86UE8,Q96SB4,Q99986,P48729 23
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Ubiquitin-conjugating enzyme, active site [IPR023313] 0.5236723793853215 0.9968537163517928 0.31883552021935 0.9999999996871304 0.439013455233607 7 Q16763,P61088 2
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Cysteine peptidase, cysteine active site [IPR000169] 0.601445890862994 0.5660448238009566 0.5713633100708382 1.0 0.6385825230203486 4 Q13867,P17655 2
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Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.5996000588546313 0.3778598871666703 0.7055346824420341 1.0 0.758782583003697 3 Q8TBC4 1
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Nucleoside diphosphate kinase, active site [IPR023005] 0.3668205267445147 0.0272211429716753 0.9782833523006658 1.0 0.9936880905159504 3 P22392,Q13232 2
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Tyrosine-protein kinase, active site [IPR008266] 0.2347349982942952 0.0167618144986946 0.9866266332300602 1.0 0.9936880905159504 5 P07948 1
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP8", "CDC34", "CDC7", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "FYN", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "LYN", "MAP2K1", "MAP2K2", "MAP2K7", "MAP3K7", "MAPK1", "MAPK3", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCA", "PRKCD", "PRPF4B", "PRSS3", "PTK7", "PTPN1", "PTPN11", "PTPN2", "PTPN9", "PTPRF", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SEC11C", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["BLMH", "BUB1", "CAMK1", "CAPN2", "CDC7", "CDK1", "CDK12", "CDK4", "CHEK1", "CSNK1A1", "CSNK2A2", "GAK", "GSK3B", "LYN", "MAP2K1", "MAPK3", "NME2", "NME3", "PAK2", "PLK1", "PRKCD", "ROCK1", "SLK", "SRPK1", "SRPK2", "TLK2", "UBA3", "UBE2N", "UBE2S", "VRK1", "WNK1"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}
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interpro_binding_site/basic/plot_0.png
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Git LFS Details
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interpro_binding_site/basic/plot_1.png
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Git LFS Details
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:783bd973f33b27b529e2c19cd9ef9824c28b627c76c9d18db176af52783c8488
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size 84657
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3686,
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"annotations_size": 32,
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"title": "Average number of proteins per term",
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"value": 4.90625
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C114/C114_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Protein kinase, ATP binding site [IPR017441] 0.4123276807488281 1.8382894621747456 0.0660197630720054 0.8875897348416738 0.1760527015253477 54 O43683,P49841,P19784,P11802,Q13177,P07948,P06493,Q14012,Q9H2G2,Q02750,P53350,O14757,Q9NYV4,Q15375,P27361,P78362,Q13464,Q05655,O00311,Q9P289,Q9UHD2,Q86UE8,Q96SB4,Q99986,P48729 25
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Beta tubulin, autoregulation binding site [IPR013838] 0.6000439757093052 1.136983183539808 0.2555453156991856 0.9999207818779928 0.4088725051186969 6 Q9BVA1,P04350 2
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IQ motif, EF-hand binding site [IPR000048] 0.4143540768693055 0.6973161745712884 0.4856049479086111 0.9999999994225732 0.5755317901139094 11 Q7Z406,P46940,Q13576,P35579 4
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Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.6289359391965252 0.6664858534113752 0.5051006029236138 0.9999999998322968 0.5772578319127015 2 Q9UQ80 1
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EF-Hand 1, calcium-binding site [IPR018247] 0.2741829910196324 0.4786090151749043 0.6322168036818918 0.9999999999999876 0.674364590594018 40 P41208,Q96AY3,Q96D71,P31949,Q9UPN3,Q03001,P17655,Q9H4M9,P07384,Q13813,P80303,Q9H223,Q14257 13
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PPM-type phosphatase, divalent cation binding [IPR000222] 0.510314875135722 0.2743275801420637 0.7838328913050849 1.0 0.8091178232826683 2 Q9H0C8 1
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Biotin-binding site [IPR001882] 0.377240630092352 0.0653563924325235 0.9478902436059452 1.0 0.9478902436059452 4 Q13085,P05165,P11498 3
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT2", "APEX1", "APEX2", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC7", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "FYN", "GCAT", "GNPTAB", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "MCFD2", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK3", "TBK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ACACA", "BUB1", "CAMK1", "CAPN1", "CAPN2", "CDC7", "CDK1", "CDK12", "CDK4", "CETN2", "CHEK1", "CSNK1A1", "CSNK2A2", "DST", "EHD1", "EHD4", "EPHA7", "FKBP10", "GSK3B", "ILKAP", "IQGAP1", "IQGAP2", "LYN", "MACF1", "MAP2K1", "MAPK3", "MYH14", "MYH9", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PLK1", "PRKCD", "RCN2", "REPS1", "ROCK1", "S100A11", "SLK", "SPTAN1", "SRPK1", "SRPK2", "STK26", "TBK1", "TLK2", "TUBB2B", "TUBB4A", "VRK1"]}
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{}
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "2": "Mini-chromosome maintenance, conserved site [IPR018525]", "3": "Ubiquitin specific protease, conserved site [IPR018200]", "4": "Kinesin motor domain, conserved site [IPR019821]", "5": "FERM conserved site [IPR019747]", "6": "Actinin-type actin-binding domain, conserved site [IPR001589]", "7": "Zinc finger, PHD-type, conserved site [IPR019786]", "8": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "9": "Heat shock protein 70, conserved site [IPR018181]"}
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:97fe8bfa08dc5bb02069c4eec988e146b4de55dac7d23f3d3d691d2c0e0b03f1
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size 105735
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3686,
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"annotations_size": 289,
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"title": "Average number of proteins per term",
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"value": 2.9238754325259517
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C114/C114_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Ras GTPase-activating protein, conserved site [IPR023152] 0.9321389793702496 1.9324304543245825 0.0533063981719417 0.9999998667924838 0.2226514636273578 2 Q13576 1
|
| 3 |
+
Proteasome beta-type subunit, conserved site [IPR016050] 0.6977492804805119 1.929284376294408 0.0536955682550317 0.9999998817169312 0.2226514636273578 8 P49721,Q99436,P28074,P28070,P28072 5
|
| 4 |
+
Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.9397388423643672 1.8138139494229453 0.0697063741755334 0.9999999991465204 0.2370016721968138 4 P48735 1
|
| 5 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.4944067780281386 1.7643277564275772 0.0776768134431731 0.9999999999290056 0.2550977168758753 23 Q5VTR2,O60858,P19474,Q9H000 4
|
| 6 |
+
Cullin, conserved site [IPR016157] 0.8022276555283974 1.726464346021669 0.08426390829054 0.999999999991054 0.2676073570985284 5 Q13617,Q13620,Q13616,Q93034 4
|
| 7 |
+
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.5306347753929589 1.6506781767722676 0.0988043062622758 0.9999999999999124 0.2855444450979773 16 Q86WJ1,Q12873,Q92620,Q14839,Q7Z478,O60231,Q14562,Q9H2U1,P18074 9
|
| 8 |
+
Ribosomal S11, conserved site [IPR018102] 0.8564060803474485 1.6127945384204188 0.1067891530829223 0.9999999999999932 0.2991402882413548 2 P82912 1
|
| 9 |
+
Ribosomal protein L3, conserved site [IPR019926] 0.8287187839305103 1.494904202073584 0.1349394454667805 1.0 0.338550008445931 2 P39023 1
|
| 10 |
+
Fatty acid desaturase type 1, conserved site [IPR001522] 0.8260043431053202 1.483331332150991 0.1379864017068475 1.0 0.338550008445931 2 Q86SK9 1
|
| 11 |
+
Syntaxin/epimorphin, conserved site [IPR006012] 0.604189483644131 1.4780180588501235 0.1394029446542068 1.0 0.338550008445931 8 Q13277,O60499,Q86Y82 3
|
| 12 |
+
Tubulin, conserved site [IPR017975] 0.6189842055294483 1.447953778623852 0.147629977777453 1.0 0.3442795262716877 7 Q9BVA1,P23258,P04350 3
|
| 13 |
+
Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.8070032573289903 1.4022915114230718 0.1608282142064618 1.0 0.3631199523880272 2 P11216 1
|
| 14 |
+
Mini-chromosome maintenance, conserved site [IPR018525] 0.6380434782608744 1.3042457134942045 0.1921498180951202 1.0 0.4013914814388272 6 P49736,Q14566,P33993,P33991,P25205 5
|
| 15 |
+
Cadherin conserved site [IPR020894] 0.8036441120961035 1.3015893497823932 0.193056802491339 1.0 0.4013914814388272 4 Q14574 1
|
| 16 |
+
Ribosomal RNA adenine methylase transferase, conserved site [IPR020596] 0.776330076004343 1.2715714849864503 0.2035254135855564 1.0 0.4179413426521396 2 Q9UNQ2 1
|
| 17 |
+
Ribosomal protein L30, conserved site [IPR018038] 0.7725298588490771 1.2554057065663522 0.2093315188178586 1.0 0.4260338657631066 2 P18124 1
|
| 18 |
+
Methylthiotransferase, conserved site [IPR020612] 0.767372421281216 1.2334830511186 0.2173955963417375 1.0 0.4332919127087045 2 Q5VV42 1
|
| 19 |
+
DNA topoisomerase, type IIA, conserved site [IPR018522] 0.7434853420195439 1.1322834883265984 0.2575152696488973 1.0 0.479134008016836 2 Q02880 1
|
| 20 |
+
Clathrin adaptor complex, small chain [IPR000804] 0.7368278109723015 1.049483605096511 0.293955597050858 1.0 0.5166559816161175 4 P56377,Q92572,P61923 3
|
| 21 |
+
Heat shock protein Hsp90, conserved site [IPR019805] 0.798616410609747 1.0362762473996237 0.3000732840837603 1.0 0.516948115976954 3 P07900 1
|
| 22 |
+
HMG box A DNA-binding domain, conserved site [IPR017967] 0.7929123100585809 1.015473263834248 0.3098802849261644 1.0 0.5299136233352753 3 P09429 1
|
| 23 |
+
Ubiquitin specific protease, conserved site [IPR018200] 0.428250618762645 0.9832136394465756 0.3255023032710884 1.0 0.5343159566999998 15 Q93008,Q9UPU5,Q96K76,P40818,Q86UV5,P51784,Q9UPT9 7
|
| 24 |
+
Kinesin motor domain, conserved site [IPR019821] 0.4457755446251738 0.9557748322153664 0.3391860062216087 1.0 0.5415732364532869 13 P33176,Q9Y496,Q9BW19,P52732,O95239,Q96Q89,O60333,Q02241 8
|
| 25 |
+
FERM conserved site [IPR019747] 0.4689087126355594 0.897247618632887 0.3695868006880394 1.0 0.5627645095465129 9 P35241,Q9Y4F1,P26038,Q9Y490,P15311 5
|
| 26 |
+
Actinin-type actin-binding domain, conserved site [IPR001589] 0.3945054906776063 0.7847437418389412 0.4326038308446296 1.0 0.6128554270298919 15 Q01082,Q8NF91,Q9UPN3,P12814,Q03001,Q15149 6
|
| 27 |
+
Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.7195601394745164 0.7543103070103091 0.4506629147519383 1.0 0.6307641835373282 3 Q9Y2T2 1
|
| 28 |
+
Guanylate kinase, conserved site [IPR020590] 0.5083471065776342 0.7415293101145 0.4583725669695111 1.0 0.6307641835373282 6 Q12959 1
|
| 29 |
+
Ribosomal protein L13, conserved site [IPR023563] 0.6473941368078175 0.7379853835689302 0.4605233312331358 1.0 0.6307641835373282 2 P40429 1
|
| 30 |
+
GTP1/OBG, conserved site [IPR006074] 0.6237785016286643 0.6468702294627804 0.5177159348342055 1.0 0.6709412787761676 2 Q9Y295 1
|
| 31 |
+
Chromo domain, conserved site [IPR023779] 0.4178607691590892 0.5818965415479427 0.5606363701797428 1.0 0.6915166495107129 8 Q13185,O14646 2
|
| 32 |
+
Zinc finger, PHD-type, conserved site [IPR019786] 0.322742395909451 0.5395733688901957 0.5894912864896804 1.0 0.7158108478803262 21 Q9ULU4,Q12873,Q96T23,Q14839,P41229,Q9UPN9,O15164 7
|
| 33 |
+
CBX family C-terminal motif [IPR033773] 0.5808903365906621 0.4912314644049432 0.6232627472349241 1.0 0.744309644425178 2 Q14781 1
|
| 34 |
+
ABC transporter-like, conserved site [IPR017871] 0.3255250498547769 0.3794987824677545 0.7043175082328821 1.0 0.8240799995113479 14 Q9NP58,Q9NUQ8 2
|
| 35 |
+
Histidine triad, conserved site [IPR019808] 0.531758957654723 0.3340362868379506 0.7383521768378856 1.0 0.8604184641376973 2 Q9BX68 1
|
| 36 |
+
ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.2813322905192271 0.3264776256776798 0.7440630148618983 1.0 0.8635912100204362 22 P41208,P26196,Q86XP3,Q8NHQ9,Q13206,Q7L014 6
|
| 37 |
+
Fork head domain conserved site1 [IPR018122] 0.5723594895465804 0.3071156776261259 0.7587553249684333 1.0 0.86755677602343 3 Q01167,Q12948 2
|
| 38 |
+
Fork head domain conserved site 2 [IPR030456] 0.5723594895465804 0.3071156776261259 0.7587553249684333 1.0 0.86755677602343 3 Q01167,Q12948 2
|
| 39 |
+
Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.5682164236663027 0.296977155378068 0.7664839501275866 1.0 0.8721018172711517 3 P27361 1
|
| 40 |
+
Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.5531178543183636 0.2615043957786327 0.7937035600885851 1.0 0.8920216910738015 3 Q96G03 1
|
| 41 |
+
Polyamine biosynthesis domain, conserved site [IPR030373] 0.5040716612377849 0.2580896703644421 0.7963377034499681 1.0 0.8920216910738015 2 P19623 1
|
| 42 |
+
DnaJ domain, conserved site [IPR018253] 0.2960601510656082 0.2366258661831239 0.8129470516853061 1.0 0.9036219151425132 13 O75190,O60884 2
|
| 43 |
+
Heat shock protein 70, conserved site [IPR018181] 0.3033440084663325 0.2089382801076887 0.8344964203936915 1.0 0.9204941431060184 10 Q92598,P34932,P54652,Q0VDF9,Q9Y4L1,O95757 6
|
| 44 |
+
Intermediate filament protein, conserved site [IPR018039] 0.2970047637752936 0.1529575554832401 0.8784317471518506 1.0 0.950811891111928 8 P08670 1
|
| 45 |
+
4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.4457833268574412 0.0822361879154189 0.9344588970939096 1.0 0.9758328837152674 3 O00217 1
|
| 46 |
+
ATPase, AAA-type, conserved site [IPR003960] 0.2087462835957241 0.0712186735013952 0.9432237198475864 1.0 0.9805455217120592 21 Q13608 1
|
| 47 |
+
Calreticulin/calnexin, conserved site [IPR018124] 0.2799348357317567 0.0108797288231229 0.9913194035981744 1.0 1.0 3 P27797,P27824 2
|
interpro_conserved_site/selections.json
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubby, C-terminal, conserved site [IPR018066]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ARSA", "ATAD1", "ATAD2", "ATG16L1", "ATM", "ATP5C1", "ATP5O", "ATP7B", "ATR", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRPF3", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD2", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRELD2", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ISCA2", "IVD", "KDM2A", "KDM5A", "KDM5C", "KDSR", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LONRF2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "N6AMT1", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PEX1", "PEX6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBFA", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RNF2", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCD5", "SCP2", "SDHB", "SEC11A", "SEC11C", "SEC61A1", "SERPINB6", "SERPINH1", "SHPRH", "SLC1A5", "SLC27A2", "SLC27A4", "SLC5A6", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM2", "STMN1", "STOM", "STRN", "STRN3", "STX10", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLE4", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TULP3", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR37", "WDR41", "WDR47", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB6", "ABCF3", "ACTN1", "AP1S2", "AP3M1", "AP3S1", "CALR", "CANX", "CBX2", "CBX3", "CDKAL1", "CETN2", "CHD1", "CHD1L", "CHD3", "CHD4", "COPZ1", "CUL1", "CUL2", "CUL4B", "CUL5", "DDX10", "DDX42", "DDX46", "DDX55", "DDX6", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DIMT1", "DLG1", "DNAJA2", "DNAJB6", "DRG1", "DSC3", "DST", "ERCC2", "EZR", "FARP1", "FOXC1", "FOXK2", "HINT2", "HMGB1", "HSP90AA1", "HSPA14", "HSPA2", "HSPA4", "HSPA4L", "HSPH1", "HYOU1", "IDH2", "IQGAP2", "KDM5C", "KIF11", "KIF1B", "KIF20B", "KIF23", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "MACF1", "MAPK3", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "MKRN2", "MRPS11", "MSN", "NDUFS8", "PEX6", "PGM2", "PLEC", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PYGB", "RDX", "RNF20", "RPL13A", "RPL3", "RPL7", "RSF1", "SCD5", "SPTBN1", "SRM", "STX10", "STX12", "STX3", "SYNE1", "TLN1", "TOP2B", "TRIM13", "TRIM21", "TRIM24", "TRIM33", "TUBB2B", "TUBB4A", "TUBG1", "USP11", "USP22", "USP24", "USP47", "USP48", "USP8", "USP9X", "VIM", "ZMYND8"]}
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{"0": "BRCT domain [IPR001357]"}
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{"0": "BRCT domain [IPR001357]", "1": "Zinc finger, RING-type [IPR001841]", "2": "SNF2, N-terminal [IPR000330]", "3": "AP complex, mu/sigma subunit [IPR022775]", "4": "TOG domain [IPR034085]", "5": "SH3 domain [IPR001452]", "6": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "7": "MCM domain [IPR001208]", "8": "MCM N-terminal domain [IPR027925]", "9": "MCM OB domain [IPR033762]", "10": "MCM, AAA-lid domain [IPR041562]", "11": "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "12": "MPN domain [IPR037518]", "13": "Protein kinase domain [IPR000719]", "14": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "15": "Kinesin motor domain [IPR001752]", "16": "Ubiquitin-conjugating enzyme E2 [IPR000608]", "17": "Ubiquitin specific protease domain [IPR028889]", "18": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "19": "K Homology domain, type 1 [IPR004088]", "20": "Proteasome component (PCI) domain [IPR000717]", "21": "FERM domain [IPR000299]", "22": "Helicase, C-terminal [IPR001650]", "23": "RNA recognition motif domain [IPR000504]", "24": "FERM central domain [IPR019748]", "25": "Band 4.1 domain [IPR019749]", "26": "K Homology domain [IPR004087]", "27": "Domain of unknown function DUF1605 [IPR011709]", "28": "Helicase-associated domain [IPR007502]", "29": "Zinc finger, CCCH-type [IPR000571]", "30": "Calponin homology domain [IPR001715]", "31": "SH2 domain [IPR000980]", "32": "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "33": "EF-hand domain [IPR002048]", "34": "Small GTP-binding protein domain [IPR005225]", "35": "AAA+ ATPase domain [IPR003593]", "36": "RNA helicase, DEAD-box type, Q motif [IPR014014]", "37": "SANT/Myb domain [IPR001005]", "38": "KOW [IPR005824]", "39": "DEAD/DEAH box helicase domain [IPR011545]"}
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