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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +10 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/basic/plot_1.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +9 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/basic/plot_3.png +3 -0
- interpro_conserved_site/basic/plot_4.png +3 -0
- interpro_conserved_site/basic/plot_5.png +3 -0
- interpro_conserved_site/basic/plot_6.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +1 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +42 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_14.png +3 -0
- interpro_domain/basic/plot_15.png +3 -0
- interpro_domain/basic/plot_16.png +3 -0
- interpro_domain/basic/plot_17.png +3 -0
- interpro_domain/basic/plot_18.png +3 -0
- interpro_domain/basic/plot_19.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_20.png +3 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
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interpro_active_site/basic/plot_0.png
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Git LFS Details
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:c5ab6e652da2062341396ccb1c547320566c3f978f7720dc0a81cae5b1e8c522
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size 76123
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3351,
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"annotations_size": 59,
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"title": "Average number of proteins per term",
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"value": 2.7966101694915255
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C119/C119_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.8052568697729915 1.418016961586697 0.1561858128001538 0.999955479241404 0.5759351847005674 3 P00390,Q16881 2
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Nucleoside diphosphate kinase, active site [IPR023005] 0.6801778589702918 0.945050888630194 0.3446328964254652 0.9999999999851203 0.7129906734475638 3 P15531 1
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Serine/threonine-protein kinase, active site [IPR008271] 0.3014442961993416 0.9427951490715544 0.3457856934384358 0.9999999999865884 0.7129906734475638 59 P54646,P78362,Q16513,O14965,P17612,P24941,O15111,O14757,Q99986,Q00534,Q13557,P53350,Q96SB4,Q96KB5,P36507,Q16512,P33981,P45985,P49760,P19784,Q13555,Q13164,Q7KZI7 23
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Thiolase, active site [IPR020610] 0.5854550995352338 0.9337108961104542 0.350453042881006 0.9999999999912094 0.7129906734475638 5 Q9BWD1,P09110,P42765 3
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Tyrosine-protein kinase, active site [IPR008266] 0.4811970614321738 0.4940761201886595 0.6212524218684485 1.0 0.8867527963289757 4 Q13308 1
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Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.5265830346475372 0.4174669706045757 0.6763368785559984 1.0 0.8867527963289757 3 Q8TBC4,P22314 2
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Beta-ketoacyl synthase, active site [IPR018201] 0.5386682591818516 0.0694836173426031 0.9446046726007092 1.0 1.0 2 Q9NWU1 1
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L-lactate dehydrogenase, active site [IPR018177] 0.5192594804419275 0.0564927838019275 0.954949244038247 1.0 1.0 2 P00338 1
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Thiolase, acyl-enzyme intermediate active site [IPR020615] 0.2669601613701106 0.0312180121494308 0.9750956752969232 1.0 1.0 5 P09110,P42765,P55084 3
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interpro_active_site/selections.json
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{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAPN1", "CAPN2", "CAPN5", "CASP6", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDC7", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K7", "MAP3K7", "MAPK1", "MAPK3", "MAPK7", "MARK2", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3B", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ACAA1", "ACAA2", "ACAT2", "AURKA", "CAMK2D", "CAMK2G", "CDK2", "CDK6", "CHEK1", "CHUK", "CLK2", "CSNK2A2", "GSR", "HADHB", "LDHA", "MAP2K2", "MAP2K4", "MAPK7", "MARK2", "NME1", "OXSM", "PBK", "PKN1", "PKN2", "PLK1", "PRKAA2", "PRKACA", "PTK7", "SRPK1", "SRPK2", "TTK", "TXNRD1", "UBA1", "UBA3", "VRK1"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"}
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interpro_binding_site/basic/plot_0.png
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Git LFS Details
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interpro_binding_site/basic/plot_1.png
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:c0efd6be3c9652c7149e5616f08d0da7ad6346ba0d72b4683c2f523522553ee8
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size 74347
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3351,
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"annotations_size": 33,
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"title": "Average number of proteins per term",
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"value": 4.696969696969697
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C119/C119_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Biotin-binding site [IPR001882] 0.7783089333731715 1.697389960034904 0.0896229594470687 0.9548868885469588 0.7437196587542092 4 Q96RQ3,P05165,P11498 3
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Protein kinase, ATP binding site [IPR017441] 0.3740027165638312 1.3346426874702888 0.1819933197236296 0.9986787771925494 0.852870515061821 56 P54646,P78362,Q16513,O14965,P17612,P24941,O15111,O14757,Q13043,Q99986,Q00534,Q15375,Q13557,P53350,Q96SB4,Q9P289,P36507,Q16512,P33981,P45985,P49760,P19784,Q13555,Q13164,Q7KZI7 25
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Beta tubulin, autoregulation binding site [IPR013838] 0.5255605381166001 0.9177046196969108 0.3587735284494746 0.9999995720651896 0.9351004245311292 6 Q13885,P07437,P68371,Q9BVA1,P04350 5
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Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.8656315318005203 0.7573426776763507 0.4488445886540031 0.9999999971023597 0.9351004245311292 2 P34897 1
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PPM-type phosphatase, divalent cation binding [IPR000222] 0.5241618274433675 0.4102835873987084 0.6815979303257464 1.0 0.9351004245311292 3 O15355 1
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Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.6685577784413261 0.2392826454267917 0.810886421534454 1.0 0.9351004245311292 2 O75600 1
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Peptidase M16, zinc-binding site [IPR001431] 0.3786610878661012 0.2074612435886446 0.8356496573331094 1.0 0.9351004245311292 5 O43847,Q10713,P14735,O75439 4
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IQ motif, EF-hand binding site [IPR000048] 0.263021406151365 0.0597726138825841 0.9523367375216244 1.0 0.9820972605691752 10 Q9Y4I1 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMK4", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHUK", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "IRAK1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["AURKA", "CAMK2D", "CAMK2G", "CDK2", "CDK6", "CHEK1", "CHUK", "CLK2", "CSNK2A2", "EPHA7", "GCAT", "IDE", "MAP2K2", "MAP2K4", "MAPK7", "MARK2", "MCCC1", "MYO5A", "NRDC", "PC", "PCCA", "PKN1", "PKN2", "PLK1", "PMPCA", "PMPCB", "PPM1G", "PRKAA2", "PRKACA", "SHMT2", "SRPK1", "SRPK2", "STK26", "STK4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "VRK1"]}
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interpro_conserved_site/advanced/idx2term.json
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{}
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interpro_conserved_site/basic/idx2term.json
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "WD40 repeat, conserved site [IPR019775]", "2": "Tubulin, conserved site [IPR017975]", "3": "Kinesin motor domain, conserved site [IPR019821]", "4": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "5": "Zinc finger, RING-type, conserved site [IPR017907]", "6": "Ubiquitin specific protease, conserved site [IPR018200]"}
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interpro_conserved_site/basic/plot_0.png
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Git LFS Details
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interpro_conserved_site/basic/plot_1.png
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Git LFS Details
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interpro_conserved_site/basic/plot_2.png
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Git LFS Details
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interpro_conserved_site/basic/plot_3.png
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Git LFS Details
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interpro_conserved_site/basic/plot_4.png
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Git LFS Details
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interpro_conserved_site/basic/plot_5.png
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Git LFS Details
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interpro_conserved_site/basic/plot_6.png
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Git LFS Details
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:01fec7dae1c5653fbb66e1f209a3ca7b2189e82d2f7a96e26a1b8daa0c9cabff
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size 84231
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3351,
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| 4 |
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"annotations_size": 281,
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| 5 |
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"title": "Average number of proteins per term",
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| 6 |
+
"value": 2.8220640569395017
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C119/C119_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Proteasome beta-type subunit, conserved site [IPR016050] 0.6123071648152276 1.294434291781341 0.1955154521600561 1.0 0.6314924374365033 8 Q99436,P28072,P49721,P49720,P28070,P20618 6
|
| 3 |
+
WD40 repeat, conserved site [IPR019775] 0.343955285395659 1.2687891887785314 0.2045162620797684 1.0 0.6457198836451118 58 P63244,Q12788,Q96DI7,Q9BQ67,Q676U5,Q9NZJ0,O76071,Q86W42,Q05048,O75717,Q8TEQ6,Q13610,P57737,P78406,Q9NV06,P62873 16
|
| 4 |
+
NUDIX hydrolase, conserved site [IPR020084] 0.6552323292886704 1.1877250713874017 0.2349417428705154 1.0 0.7023258483682429 4 Q9UKK9,P36639 2
|
| 5 |
+
Tr-type G domain, conserved site [IPR031157] 0.5836173162305955 1.170929058912879 0.2416272935543792 1.0 0.7034213243833214 7 P13639,Q8N442 2
|
| 6 |
+
Dynein light chain, type 1/2, conserved site [IPR019763] 0.9587936697521616 1.063000057566465 0.2877819252313021 1.0 0.7220242945535347 2 P63167 1
|
| 7 |
+
4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.7036591828197152 1.032891046056533 0.3016548894811488 1.0 0.7342983841832271 3 O00217 1
|
| 8 |
+
ABC transporter-like, conserved site [IPR017871] 0.5538599185627646 1.025677839356478 0.3050434633793879 1.0 0.7342983841832271 8 Q9UG63,P08183 2
|
| 9 |
+
Mini-chromosome maintenance, conserved site [IPR018525] 0.5441351272787894 1.0013194438781825 0.3166723955350727 1.0 0.7477726314735751 6 P33992,P25205 2
|
| 10 |
+
IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.6726403823177909 0.9170596034308962 0.3591114079114168 1.0 0.7971792952319424 3 P12268,Q9P2T1 2
|
| 11 |
+
Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.90773365183637 0.8929543650179154 0.3718816116389571 1.0 0.7971792952319424 2 P09972 1
|
| 12 |
+
Tubulin, conserved site [IPR017975] 0.5213576303440945 0.8881209711547042 0.3744756831694533 1.0 0.7971792952319424 7 Q13885,P07437,P68371,Q9BVA1,P04350 5
|
| 13 |
+
Kinesin motor domain, conserved site [IPR019821] 0.5225077613170992 0.8492367933655305 0.3957495436862661 1.0 0.8237453464877095 14 O00139,Q96Q89,Q9BW19,Q99661,O60333,O95235,O95239,Q12756,Q14807,O60282 10
|
| 14 |
+
DnaJ domain, conserved site [IPR018253] 0.5033476930089488 0.7896213590235698 0.429748930590478 1.0 0.8564499964249951 9 Q9UBS4,Q9NVH1,Q99543,Q96EY1 4
|
| 15 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.5364889267824133 0.7023812217581749 0.4824414528242964 1.0 0.8860526028995247 4 Q9UBQ7,O43175 2
|
| 16 |
+
Phosphofructokinase, conserved site [IPR015912] 0.599507939719079 0.6538333308910887 0.5132191900881728 1.0 0.9151926358876834 3 P17858 1
|
| 17 |
+
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.4753746296933603 0.6350153984222414 0.5254183721946788 1.0 0.9151926358876834 16 Q12873,O60231,Q9H2U1,Q8IX18,Q7Z478,Q86WJ1,P18074 7
|
| 18 |
+
Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.8014332636607988 0.5629138758693271 0.5734935310344236 1.0 0.9473956612673752 2 P15880 1
|
| 19 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.4570057028387019 0.5589088740280533 0.5762239128109024 1.0 0.9473956612673752 20 Q96T88,Q12933,O95376,Q99590,Q9UPN9,Q7Z6J0,P19474,Q14258,Q9P1Y6,Q8TDB6,O15344 11
|
| 20 |
+
Mrp, conserved site [IPR000808] 0.5692951015531542 0.5517164860856538 0.5811426130020969 1.0 0.9473956612673752 3 P53384,Q9Y5Y2 2
|
| 21 |
+
Ribosomal protein S9, conserved site [IPR020574] 0.7757539564048935 0.490787628502831 0.6235766610136171 1.0 0.947873728050962 2 P82933 1
|
| 22 |
+
DNA ligase, ATP-dependent, conserved site [IPR016059] 0.775455359808892 0.4899715940575563 0.6241539997223338 1.0 0.947873728050962 2 P18858 1
|
| 23 |
+
Ribosomal protein S2, conserved site [IPR018130] 0.767393251716928 0.468147875975325 0.6396788441333416 1.0 0.947873728050962 2 P08865 1
|
| 24 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.5430107526881591 0.4674881968049089 0.6401506348012462 1.0 0.947873728050962 3 Q9GZZ9,O43175 2
|
| 25 |
+
Actinin-type actin-binding domain, conserved site [IPR001589] 0.4211333370139329 0.4218025873246523 0.6731691170351748 1.0 0.9506088872161172 14 Q03001,Q14651 2
|
| 26 |
+
Thioredoxin, conserved site [IPR017937] 0.403434784372872 0.3783894013956091 0.7051413404071543 1.0 0.966559593436148 10 O43396,O95881 2
|
| 27 |
+
Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.7273813078530953 0.3663102424510365 0.7141335875918009 1.0 0.9676980890637674 2 P11766 1
|
| 28 |
+
Actin/actin-like conserved site [IPR020902] 0.501126233597252 0.3445912698529731 0.7304016699044205 1.0 0.9676980890637674 3 P61160 1
|
| 29 |
+
Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.3902106023648009 0.3120397220868386 0.7550103355349527 1.0 0.9722358954173786 15 Q9UGM6 1
|
| 30 |
+
3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.4795561447099004 0.2878273337298772 0.7734789130539976 1.0 0.9790431286854656 3 Q08426 1
|
| 31 |
+
Ribosomal protein L24/L26, conserved site [IPR005825] 0.6637802329053444 0.2302870062646472 0.8178687568038725 1.0 0.9930365617026587 2 P61254 1
|
| 32 |
+
Hexapeptide transferase, conserved site [IPR018357] 0.6554195282173798 0.2150474708913821 0.8297303078339222 1.0 0.9930365617026587 2 Q96IJ6 1
|
| 33 |
+
Chaperonin TCP-1, conserved site [IPR002194] 0.3288239849474541 0.1715186777465588 0.8638159453368439 1.0 0.9930365617026587 8 P48643 1
|
| 34 |
+
Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131] 0.617796357121531 0.1545312373702922 0.8771908831636519 1.0 0.9930365617026587 2 P12955 1
|
| 35 |
+
Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.4109916367980719 0.1431042951841289 0.8862078127923827 1.0 0.9930365617026587 3 O00469,Q02809 2
|
| 36 |
+
Ubiquitin specific protease, conserved site [IPR018200] 0.3190494309426605 0.1319963554219799 0.8949871744779867 1.0 0.9930365617026587 16 Q14694,Q8TEY7,O94966,O94782,P54578 5
|
| 37 |
+
RNA polymerase, beta subunit, conserved site [IPR007121] 0.384707287933078 0.1033006801079569 0.917724335860218 1.0 0.9934404399108528 3 Q9NW08,P30876 2
|
| 38 |
+
Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628] 0.5661391460137403 0.0928432763234235 0.9260280699324416 1.0 0.9934404399108528 2 P11586 1
|
| 39 |
+
EGF-like, conserved site [IPR013032] 0.5476261570618154 0.0764323647331738 0.9390751215732184 1.0 0.9934404399108528 2 Q04721 1
|
| 40 |
+
Ribosomal protein L3, conserved site [IPR019926] 0.5458345774858225 0.074992328636893 0.9402208155674106 1.0 0.9934404399108528 2 P09001 1
|
| 41 |
+
DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.5455359808898206 0.0747547925426472 0.9404098114458606 1.0 0.9934404399108528 2 P19387 1
|
| 42 |
+
Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.5264257987459013 0.0609724378184997 0.9513811596376388 1.0 1.0 2 P22314 1
|
interpro_conserved_site/selections.json
ADDED
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATG16L1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX6", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CECR2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CREBBP", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DMD", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EP300", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FPGS", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXA10", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPDH1", "IMPDH2", "IQGAP1", "IQGAP2", "ISCA2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MAPK7", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MLH1", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFM", "NES", "NF1", "NF2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "REL", "RELA", "RIDA", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SH3RF1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STMN1", "STRN", "STRN3", "STX12", "STX18", "STX4", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLE4", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCF2", "ACTR2", "ADH5", "ALDOC", "ARIH2", "ATG16L1", "CCT5", "CHD1L", "CHD3", "CIAO1", "CORO7", "CSTF1", "DCAF13", "DHX16", "DHX29", "DHX36", "DHX40", "DNAJA3", "DNAJB11", "DNAJC11", "DNAJC2", "DST", "DTL", "DTX3L", "DYNLL1", "EEF2", "EHHADH", "ERCC2", "GEMIN5", "GMPPA", "GMPR2", "GNB1", "GRHPR", "GRWD1", "GUF1", "IMPDH2", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5C", "KIFC1", "LIG1", "MCM3", "MCM5", "MID1", "MRPL3", "MRPS9", "MTHFD1", "NDUFS8", "NOTCH2", "NUBP1", "NUBP2", "NUDT1", "NUDT5", "PEPD", "PFKL", "PHGDH", "PHRF1", "PLOD1", "PLOD2", "PLS1", "POLR2B", "POLR2C", "POLR3B", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB6", "PSMB7", "PWP1", "RACK1", "RAE1", "RPL26", "RPS2", "RPSA", "SCAF11", "SH3RF1", "SNRNP40", "TBL3", "THOC6", "TRAF2", "TRIM21", "TRIM25", "TRIM33", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TXNDC12", "TXNL1", "UBA1", "UBA5", "UHRF1", "USP1", "USP10", "USP14", "USP19", "USP33", "WARS2", "WDHD1"]}
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{"0": "K Homology domain, type 1 [IPR004088]", "1": "K Homology domain [IPR004087]", "2": "Helicase-associated domain [IPR007502]", "3": "Domain of unknown function DUF1605 [IPR011709]", "4": "Translational (tr)-type GTP-binding domain [IPR000795]", "5": "Protein kinase domain [IPR000719]", "6": "Tubulin/FtsZ, GTPase domain [IPR003008]", "7": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "8": "Kinesin motor domain [IPR001752]", "9": "Forkhead-associated (FHA) domain [IPR000253]", "10": "Biotin/lipoyl attachment [IPR000089]", "11": "BRCT domain [IPR001357]", "12": "Zinc finger, RING-type [IPR001841]", "13": "Calponin homology domain [IPR001715]", "14": "GTP binding domain [IPR006073]", "15": "KOW [IPR005824]", "16": "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "17": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "18": "JmjC domain [IPR003347]", "19": "Thioredoxin domain [IPR013766]", "20": "Small GTP-binding protein domain [IPR005225]", "21": "AAA+ ATPase domain [IPR003593]", "22": "DEAD/DEAH box helicase domain [IPR011545]", "23": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "24": "Ubiquitin specific protease domain [IPR028889]", "25": "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "26": "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "27": "Pleckstrin homology domain [IPR001849]", "28": "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "29": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "30": "C2 domain [IPR000008]", "31": "Chromo/chromo shadow domain [IPR000953]"}
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