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6efd261 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Mitochondrial protein import 0.7182435402619275 3.7537439656027094 0.0001742128119763 0.2182217513579316 0.0137873011307534 32 O60830,Q9Y5L4,Q99595,O43615,Q8N4H5,Q9Y5J9,Q9NX63,P12235,P21796,Q9NS69,O75390,Q13505,Q10713 13
Protein localization 0.5357793642883409 3.5506932742882342 0.0003842179104001 0.4189998303024992 0.0193892824069769 68 O60830,Q99595,O43615,Q9Y5J9,P21796,P40855,O75381,Q9NS69,O75390,Q8N4H5,P50542,O15254,P09601,Q08426,Q10713,O43681,P51648,Q9Y5L4,Q9NX63,P12235,Q13505 21
Proton coupled monocarboxylate transport 0.9638698118841406 3.2861755179451 0.0010155770688999 0.7620606747921598 0.0298960499657433 2 P35613 1
Transport of small molecules 0.4100127391033706 3.016740642026478 0.0025550832254643 0.9730818047967394 0.0456611846064231 145 Q14997,P30519,Q70HW3,Q93050,P21796,P35613,Q9Y487,P08183,Q8WTV0,P45880,Q9Y5K8,P09601,Q9HD20,P55036,Q10713,Q96PU5,Q9UBX3,P49721,P12235,Q8NB49,P53985 21
Sulfide oxidation to sulfate 0.9431170787936418 2.8042549121793487 0.0050433014207684 0.999210582561494 0.0712618490754585 3 Q9UBX3 1
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5836402432894393 2.776679982177853 0.0054917220368246 0.999582484509475 0.0760765023336596 32 Q9UJW0,Q96FJ2,P31948,Q13409,Q13561 5
Abc transporters in lipid homeostasis 0.8262167811286983 2.669074562675071 0.0076060563089432 0.9999793632792804 0.0951189765193303 2 P40855 1
Copi mediated anterograde transport 0.4909326775789816 2.6660800179689863 0.0076741424792665 0.9999812700169968 0.0951189765193303 50 Q9UJW0,P24390,P48444,P83436,Q96FJ2,Q14789,P04350,Q13409,P52907,P61923,P47755,O15498,Q99747,Q13561,Q01082,O60763,Q08379,Q9Y3B3,P49755,Q13813 20
Attachment of gpi anchor to upar 0.8208420424007159 2.644045935484139 0.0081921537742817 0.9999910440104546 0.0997889076125869 2 Q92643 1
Selective autophagy 0.557387898197004 2.6135655338790476 0.00896028978864 0.999997003163178 0.1072956734860033 33 Q8N4H5,P08670,Q96FJ2,P21796,P54619,Q9NS69,P04350,Q13409 8
Transport of bile salts and organic acids metal ions and amine compounds 0.8849602831447149 2.5587237689329503 0.0105057182787047 0.999999669647935 0.1125165340307881 3 P35613 1
Nef and signal transduction 0.7978501045088118 2.536162683904686 0.0112074655790546 0.999999878767916 0.1125165340307881 2 P63000 1
Copi independent golgi to er retrograde traffic 0.5770607662149765 2.523836498214593 0.0116081904437261 0.9999999316290116 0.1125165340307881 28 Q9UJW0,Q96FJ2,Q13409,P04350,Q13561 5
Formation of fibrin clot clotting cascade 0.8613912273348243 2.4572238389044916 0.014001541543434 0.9999999977760684 0.1213753263857195 3 P42785 1
Metabolism of porphyrins 0.8283883183139894 2.417809964041914 0.0156142290307328 0.9999999997799064 0.1318116193099562 9 P53004,P09601,P30519 3
Heme degradation 0.918910474810926 2.3645862296573186 0.0180502248050817 0.9999999999933604 0.1435582341110878 4 P30519,P09601 2
Intra golgi and retrograde golgi to er traffic 0.4026653915956631 2.279161361935761 0.0226574749816259 0.9999999999999912 0.1702926178140291 88 Q10472,Q9UJW0,P24390,P48444,P51151,Q9H2M9,P83436,Q96FJ2,P33908,Q13409,P04350,O00139,O95235,P52907,P61923,P47755,Q6NUQ1,O15498,O43237,Q99747,Q13561,P33176,Q9H0B6,Q8IWJ2,Q99661,Q9NRW7,Q9P2W9,Q9BW19,Q9NS87,Q9Y496,Q8TBA6,O60333,Q9Y3B3,Q8N1B4,P49755 35
Organelle biogenesis and maintenance 0.4015736762706502 2.2689318704793795 0.0232724692664478 0.9999999999999964 0.1718534341140853 91 Q96FJ2,O75964,P54619,Q04837,Q13409,P04350,P23258,Q99996,Q15019,Q9NVH1,P54646,Q10713,Q13561,O75695,Q00059,P00367,P06576,P56134,Q9UPT5,P17252,P18859,Q9NX63,Q13505 23
Golgi to er retrograde transport 0.414259188018446 2.246126076404136 0.0246959335174035 0.9999999999999996 0.1767277298280506 71 Q10472,Q9UJW0,P24390,P48444,Q9H2M9,Q96FJ2,P04350,Q13409,Q9UBF2,O00139,O95235,P52907,P61923,P47755,Q6NUQ1,O43237,Q99747,Q13561,P33176,Q9H0B6,Q99661,Q9P2W9,Q9BW19,Q9NS87,Q9Y496,O60333,Q9Y3B3,P63167,P49755 29
Rhov gtpase cycle 0.6767938484080996 2.2360221818929302 0.0253503181846874 0.9999999999999998 0.1798168228003756 15 Q9NNW5,Q13177,P06753,Q03001,Q16512,Q13813,P67936 7
Sensory processing of sound 0.6296502979433551 2.2180630607293264 0.0265505330193118 1.0 0.1821322676840278 18 P35241,Q9Y2J2,P52907,Q01082,P15311,P47755,Q14651,P26038,Q13813 9
Transport to the golgi and subsequent modification 0.4061049533011802 2.2180283481090752 0.0265528996057393 1.0 0.1821322676840278 75 Q9UJW0,P24390,Q08379,Q96FJ2,Q14789,Q9Y3B3,P55735,P33908,P04350,Q13409,Q13561 11
Iron uptake and transport 0.6332553547169287 2.151562659151136 0.0314318157725699 1.0 0.201591518514665 17 Q93050,P09601,Q9Y487,P30519 4
Autophagy 0.4356084304108076 2.144936916406309 0.0319578911162667 1.0 0.201591518514665 51 Q8N4H5,P08670,Q8WUX9,Q96FJ2,P21796,P54619,Q9NS69,P04350,Q13409 9
Phase 0 rapid depolarisation 0.7154374440131412 2.1385878527242252 0.0324690621538641 1.0 0.2030034726699558 2 Q13555 1
Er to golgi anterograde transport 0.4049258617496797 2.133699286982905 0.0328674044813181 1.0 0.2031067436168971 71 Q9UJW0,P24390,Q08379,Q96FJ2,Q14789,Q9Y3B3,P55735,P04350,Q13409,Q13561 10
Degradation of cysteine and homocysteine 0.8250228018255928 2.1023206500076568 0.0355251968633951 1.0 0.2114110544161939 6 Q9UBX3 1
Cytoprotection by hmox1 0.4056417729386866 2.085133193250612 0.0370572119875469 1.0 0.2172690478771944 67 Q14997,P30519,Q8TCT9,P09601,P14854,P55036,P53004 7
Sulfur amino acid metabolism 0.7008209364036297 2.083167605745879 0.0372359487648972 1.0 0.2174148578710734 12 Q13126,Q9UBX3,Q9Y6N5 3
Nicotinamide salvaging 0.767002307336049 2.0392588013556243 0.0414242050807989 1.0 0.2360177491095519 3 P43490 1
Ion channel transport 0.5314668172788204 2.0124195392505357 0.0441757304967536 1.0 0.2476996317139398 25 Q96PU5,Q9Y5K8,Q93050,Q9HD20,Q8NB49,Q9Y487 6
Disinhibition of snare formation 0.7584639538775552 2.0005709669276963 0.045438644976222 1.0 0.2510566251040083 3 P17252 1
Collagen formation 0.6625245985515902 1.9777953596143905 0.0479517972045384 1.0 0.260895633300839 13 Q32P28,Q03001,O60568 3
Methionine salvage pathway 0.8241275705927971 1.976722271857511 0.0480730318759534 1.0 0.260895633300839 4 Q13126 1
Displacement of dna glycosylase by apex1 0.7529868578255599 1.975681044188165 0.0481909131574798 1.0 0.260895633300839 3 P13051,P27695 2
Vitamin d calciferol metabolism 0.8207539558904616 1.9626428023730296 0.0496876935656986 1.0 0.2659420871527737 4 P04062 1
Sema4d mediated inhibition of cell attachment and migration 0.7490327256086192 1.957677123457156 0.0502679112407109 1.0 0.2680322965400927 3 P63000 1
Cholesterol biosynthesis 0.5859027221653436 1.9499306407141548 0.0511843864948531 1.0 0.26986394819861 18 P37268,Q13907,Q15126,Q15125,Q16850,Q15800,Q15392 7
Anchoring of the basal body to the plasma membrane 0.4936700276041149 1.9452410030148788 0.0517459790234853 1.0 0.2718106630490139 29 P17252,Q13561,Q13409,P23258,P04350,Q99996,Q15019 7
Cilium assembly 0.4084812971638705 1.9290394673788984 0.05372596276995 1.0 0.2790984757130124 54 O75695,P17252,Q96FJ2,Q13561,Q10713,Q9UPT5,Q13409,P23258,P04350,Q99996,Q15019 11
Mitochondrial calcium ion transport 0.6220378828033931 1.9259173809760148 0.0541146908158971 1.0 0.2800881249921709 15 P45880,P21796,Q96TA2,Q10713,Q9UJZ1 5
Metabolism of folate and pterines 0.7221328204410908 1.919256717543114 0.0549518527519017 1.0 0.283383094665829 9 Q9H2D1 1
Sensory perception 0.4959211581258241 1.9108143900489072 0.0560284377822404 1.0 0.2859260469781798 28 P35241,P49354,Q9Y2J2,P52907,Q01082,P53582,P15311,P50579,P47755,Q14651,P17252,P26038,Q13813,Q6NUM9 14
Transport of inorganic cations anions and amino acids oligopeptides 0.7321755776687467 1.887962772283896 0.0590309483850988 1.0 0.2952258669277467 8 Q70HW3 1
Dcc mediated attractive signaling 0.7318643819238754 1.87917497076854 0.060220606023652 1.0 0.2952258669277467 3 P63000 1
Synthesis of very long chain fatty acyl coas 0.751681576980995 1.8771193120707184 0.0605017430980798 1.0 0.2952258669277467 7 Q4G176 1
Sensory processing of sound by outer hair cells of the cochlea 0.6420416611831331 1.866494798882755 0.061972171065213 1.0 0.2952258669277467 13 P35241,Q9Y2J2,Q01082,P15311,Q14651,P26038,Q13813 7
Synthesis of pips at the er membrane 0.7267025089605681 1.8554698108208625 0.063529166392358 1.0 0.2970662273544269 3 P42356,Q13614 2
Aurka activation by tpx2 0.4725430991874841 1.8304823395782508 0.0671778452096423 1.0 0.3062009525200793 30 P17252,Q13409,P23258,P04350,Q99996,Q13561,O75330 7
Diseases of mitotic cell cycle 0.6114068422652834 1.7932599238014952 0.0729313723222973 1.0 0.3251480033754603 14 Q9H1A4,Q9UJX5,Q00534,P24941,Q9UJX4,Q9UJX2 6
Mitophagy 0.6455787545745646 1.792461700190344 0.0730590389676062 1.0 0.3251480033754603 12 P21796,Q9NS69 2
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.711288296045634 1.7844129671298126 0.0743565855391477 1.0 0.3278296283222043 3 P63000 1
Pink1 prkn mediated mitophagy 0.6940925233943296 1.783683578334146 0.0744750960307343 1.0 0.3278296283222043 9 P21796,Q9NS69 2
Nicotinate metabolism 0.7632357945030428 1.7751474559621094 0.0758735429576658 1.0 0.3329481869539806 5 P43490 1
Mhc class ii antigen presentation 0.3896425037591232 1.77184515605307 0.0764202644375813 1.0 0.3334037749456673 56 Q9UJW0,Q96FJ2,P50570,P55735,P04350,Q13409,O00139,O95235,Q9Y6G9,P52907,P47755,O43237,Q13561,P33176,Q9H0B6,Q99661,Q9NS87,Q9BXW6,Q9Y496,P63167,Q15436 21
Ionotropic activity of kainate receptors 0.7066905615292612 1.7631429405150356 0.0778763844854397 1.0 0.3375439609752343 3 Q12959,Q15334 2
Nrcam interactions 0.7066905615292612 1.7631429405150356 0.0778763844854397 1.0 0.3375439609752343 3 Q12959,Q15334 2
Processive synthesis on the c strand of the telomere 0.639026832458073 1.757503991822735 0.0788319420432155 1.0 0.3404204412909566 12 P28340,P15927,P54132,P35244,P51530 5
Creatine metabolism 0.7042921515622926 1.7520342017588444 0.0797679270546498 1.0 0.3415517603885462 3 P12277 1
Runx3 regulates p14 arf 0.7037037037036967 1.7493073164618838 0.0802379119486098 1.0 0.3425261920948209 3 Q09472,P25440 2
Cdc6 association with the orc origin complex 0.7016129032257971 1.739614173232332 0.081926788850271 1.0 0.347085377996904 3 Q9UBD5,Q99741 2
Rho gtpase cycle 0.3252700939199671 1.7347802265777612 0.0827797398336565 1.0 0.347085377996904 154 P30519,Q96N67,P34897,Q8N684,Q86XL3,P49257,Q13017,Q9UNZ2,Q9Y2A7,Q03001,P51572,Q9UQB8,Q16512,Q96CS3,P31948,P12814,P67936,Q96HY6,Q14185,O75323,Q13177,Q14254,Q07065,Q16543,Q96F07,Q92888,Q9NZM3,O15173,Q13576,Q13464,P12277,P28288,P06753,P08670,Q92974,Q9NNW5,P51648,O94887,Q86UP2,Q5VTR2,P20700,Q9P0I2,Q5JTV8,Q9P2R3,Q13505,P63000,Q13813,Q01968 48
Regulation of plk1 activity at g2 m transition 0.4425802476189 1.7306787858724075 0.0835090709699442 1.0 0.3472122611078282 35 P17252,O95067,Q13409,P23258,P04350,Q99996,Q13561 7
Activation of ppargc1a pgc 1alpha by phosphorylation 0.699509690416763 1.7298567624716925 0.0836558699665426 1.0 0.3472122611078282 3 P54619 1
Cytosolic iron sulfur cluster assembly 0.6984812694745327 1.7290904425141806 0.0837929094393272 1.0 0.3472122611078282 8 P18074,Q6FI81,O76071 3
Signaling by alk in cancer 0.4458086797656412 1.724242976286901 0.0846639887629974 1.0 0.3490901911929339 34 P49589,P19174,P06753,P12270,Q8IWJ2,P62753,P27361,O43815,P35579,P26038,P51608,P67936 12
Formation of apoptosome 0.7485295234174195 1.7112977366652886 0.0870261639716216 1.0 0.3562648779455219 5 Q9NR28,Q96GX9 2
Basigin interactions 0.714926304434736 1.7093428732706473 0.0873874560729925 1.0 0.3562648779455219 7 P35613 1
Netrin 1 signaling 0.6592370946264857 1.6905394570692542 0.0909247962092907 1.0 0.3629286357167451 10 Q14185,P19174,P15311,Q00169,Q16512,P63000 6
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7098582218059031 1.6860432477669327 0.0917874697231058 1.0 0.3646064797480454 7 Q09472,Q9HCE1 2
Insulin processing 0.6582695946592135 1.6856604325449456 0.0918612220738175 1.0 0.3646064797480454 10 Q9Y4I1,Q8IYI6,Q9UPT5,P51159 4
Striated muscle contraction 0.741286428119381 1.6797451091705893 0.0930069190632645 1.0 0.3668934767742737 5 P08670,P67936 2
Ros and rns production in phagocytes 0.6849446719242086 1.664725931137518 0.0959674470718514 1.0 0.3756288163781886 8 Q9Y487,Q93050 2
Regulation of runx1 expression and activity 0.7357826713899236 1.655725456676041 0.0977774295997853 1.0 0.3805505454855126 5 Q00534 1
Fasl cd95l signaling 0.6189907435055262 1.6531410631000336 0.0983021578925775 1.0 0.3805505454855126 2 Q14790 1
Muscle contraction 0.4676935459740114 1.64481781698536 0.1000073867851187 1.0 0.3850420641072829 27 Q05682,P06753,P17252,P08670,Q13555,Q99996,P16615,P67936 8
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.744894807579518 1.6416835057817196 0.1006556116775914 1.0 0.3854373422776061 4 Q00534 1
Peptide hormone metabolism 0.5835964121894113 1.6346693676858914 0.1021183773205245 1.0 0.3899818031186517 14 Q9Y4I1,P67812,P51159,Q8IYI6,Q9UPT5 5
Mitochondrial biogenesis 0.4251145767942411 1.6307539561624738 0.1029422464907692 1.0 0.3910145007834863 37 P18859,Q15648,O00411,P00367,P06576,Q00059,Q9NVH1,Q9NX63,P54646,O75964,P56134,P54619,P25705,Q04837,O75431,Q13505 16
Recruitment of numa to mitotic centrosomes 0.4380056670409623 1.6250026132921391 0.1041620020003841 1.0 0.3945868869344311 33 P17252,Q13409,P23258,P04350,Q99996,Q9UIS9,Q13561 7
Recruitment of mitotic centrosome proteins and complexes 0.447237013080314 1.6226939194857153 0.1046548518714884 1.0 0.3953938654930835 30 P17252,Q13409,P23258,P04350,Q99996,Q9UIS9,Q13561 7
Cytochrome p450 arranged by substrate type 0.6761845592133569 1.6212198212374769 0.1049705032825183 1.0 0.3955288563685291 3 Q16850 1
Trif mediated programmed cell death 0.6118244252015552 1.616353304491562 0.1060179481220819 1.0 0.3961471576628874 2 Q14790 1
Tlr3 mediated ticam1 dependent programmed cell death 0.6118244252015552 1.616353304491562 0.1060179481220819 1.0 0.3961471576628874 2 Q14790 1
Activation of rac1 0.7388706304152926 1.6158789344024542 0.1061204909764352 1.0 0.3961471576628874 4 P63000,Q13177,Q16512 3
Collagen biosynthesis and modifying enzymes 0.6284229884943572 1.6141459803890426 0.106495765936212 1.0 0.3961471576628874 11 Q32P28,O60568 2
Maturation of sars cov 2 nucleoprotein 0.7259338424116055 1.6126531695442945 0.1068198800953403 1.0 0.3961471576628874 5 P78362 1
Activation of ampk downstream of nmdars 0.690668312011323 1.597499834125165 0.1101543346271629 1.0 0.4042807138394318 7 P54619,P04350 2
Signaling by nodal 0.6675662911819602 1.580900327550275 0.1139008294311267 1.0 0.4116160408853763 3 P27361 1
Signaling by activin 0.6675662911819602 1.580900327550275 0.1139008294311267 1.0 0.4116160408853763 3 P27361 1
Ion transport by p type atpases 0.6366294619391593 1.5761287731273144 0.1149961292098278 1.0 0.4134593653269382 10 Q8NB49,P16615,Q9HD20 3
Cellular responses to stimuli 0.270381557608586 1.5699571081933257 0.116425090179846 1.0 0.414314460135671 341 Q9UJW0,Q09472,Q14997,P30519,P62841,Q9UJX5,Q15648,Q8N1F7,Q13555,Q96FJ2,P55735,P31948,Q13409,P04350,Q92993,Q15024,Q00534,Q9Y5K8,P15927,O43242,P09601,P42345,P62081,P47755,P61254,P46778,P55036,O95070,P53004,Q9H1A4,P50914,Q9Y3B2,Q99543,Q13561,P17096,Q9UJX4,Q9Y5M8,P24941,O00231,P08865,P25398,P12270,P16104,P35244,P84098,P62917,Q9HCE1,P61289,P30043,Q9NWT6,P62899,Q9UJX2,Q9UBS4,P49721,P46782,Q8TCT9,P20700,P61513,P14854,Q02543,P62753,P15880,P27361,P02545,Q96EE3,P43307,P27635,P00390,P20042,Q9BTX1 70
Suppression of apoptosis 0.7273050929358679 1.566232505873374 0.117294195395031 1.0 0.4144672142571814 4 P27361,P14373 2
Metabolism of water soluble vitamins and cofactors 0.4074453172449865 1.5622450644169408 0.1182302681307929 1.0 0.4144672142571814 40 Q9H2D1,P43490 2
Fatty acyl coa biosynthesis 0.5578139756975667 1.551294029213511 0.1208312370594693 1.0 0.4205284186330791 15 Q4G176,P53007 2
Lipophagy 0.7227490507454615 1.5466398522009703 0.1219501142983858 1.0 0.4233796351440276 4 P54619 1
Class a 1 rhodopsin like receptors 0.6965516377187126 1.5363890670028215 0.1244429865633423 1.0 0.423911695297961 6 P07602 1
Peptide ligand binding receptors 0.6965516377187126 1.5363890670028215 0.1244429865633423 1.0 0.423911695297961 6 P07602 1
Slc mediated transmembrane transport 0.508239589689032 1.5357590051793408 0.1245974975020836 1.0 0.423911695297961 19 P53985,Q9UBX3,Q70HW3,P35613 4
Negative feedback regulation of mapk pathway 0.7199989014533107 1.5348042288418138 0.1248319237401649 1.0 0.423911695297961 4 P36507 1
G1 s specific transcription 0.6432610581194261 1.5344201235776789 0.1249263300611382 1.0 0.423911695297961 9 P00374 1
Trna modification in the mitochondrion 0.6952278775296812 1.5304407610762687 0.1259076660690561 1.0 0.423911695297961 6 O15091,Q9Y606 2
Ras activation upon ca2 influx through nmda receptor 0.7071129707113023 1.5300535425933657 0.1260034763093727 1.0 0.423911695297961 5 Q12959,Q13557,Q13555,Q15334 4
Unblocking of nmda receptors glutamate binding and activation 0.7071129707113023 1.5300535425933657 0.1260034763093727 1.0 0.423911695297961 5 Q12959,Q13557,Q13555,Q15334 4
Long term potentiation 0.7071129707113023 1.5300535425933657 0.1260034763093727 1.0 0.423911695297961 5 Q12959,Q13557,Q13555,Q15334 4
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3628772430519456 1.5245221733312375 0.1273783221882181 1.0 0.427519166869245 62 P18859,Q9P0J0,P51970,O75380,P06576,P14854,O43676,Q9UDW1,O75964,P22695,P56134,Q86Y39,Q9BQ95,O75306 14
Rhou gtpase cycle 0.5522865799449844 1.51860868443281 0.1288610238662917 1.0 0.4301434560775037 15 Q13177,Q03001,Q13813,Q16512,Q9NNW5,Q9NZM3 6
Sphingolipid de novo biosynthesis 0.6251542041998068 1.5177656845586678 0.1290734786814307 1.0 0.4301434560775037 10 P51648,Q9Y5P4,Q96G23,Q06136 4
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.6505376344085935 1.500994651732618 0.133356944886599 1.0 0.4392386086824345 3 Q13951,P17931 2
Signaling by braf and raf1 fusions 0.4617621242229526 1.4976607090612448 0.1342214250393112 1.0 0.4409678096387038 25 Q9NRY5,P36507,Q13555,P27361,P02545,Q96PU8,Q99996 7
Cristae formation 0.5020407505912289 1.4948846408972558 0.1349445513874601 1.0 0.4409678096387038 19 P18859,P06576,Q9NVH1,Q9NX63,O75964,P56134,P25705,O75431,Q13505 9
Diseases of immune system 0.7105689224906236 1.4941735539114291 0.1351302629678406 1.0 0.4409678096387038 4 O15111 1
Small interfering rna sirna biogenesis 0.6472520908004693 1.4855457530049758 0.137399312850093 1.0 0.4463108713958193 3 O75569,Q15631 2
Polo like kinase mediated events 0.6827123651693945 1.4741243750794926 0.1404481067275274 1.0 0.454126258137291 6 O95067 1
Dscam interactions 0.6403234410524405 1.4529383392837634 0.146240874837038 1.0 0.469719797830995 3 P63000 1
Diseases of signal transduction by growth factor receptors and second messengers 0.3113516105447512 1.4467909342611935 0.1479554866304688 1.0 0.4708583392091273 151 Q09472,Q14997,P49589,P49815,P62191,Q13555,Q14789,Q99996,Q92530,P67936,Q9UNM6,O15111,O43242,P42345,Q13485,Q15008,O43815,Q96PU8,Q16543,P55036,O95429,Q9NWH9,Q9NRY5,Q01082,P19174,Q09161,P06753,P36507,O00231,P12270,Q8IWJ2,P61289,P35579,P49721,Q6WCQ1,P62753,P27361,P02545,Q9UBN7,P26038,P51608,P63000 42
Switching of origins to a post replicative state 0.3575628964160782 1.431403927343554 0.1523144834845902 1.0 0.479152181790544 59 Q14997,Q9UJX5,P62191,Q92530,P25205,Q9UNM6,O43242,Q16763,P55036,Q9UJX4,Q9H1A4,P24941,O00231,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 20
Synthesis of pips at the golgi membrane 0.6212482125720251 1.4254029685667724 0.1540407504539525 1.0 0.479152181790544 9 Q99570,P42356,Q9UBF8,Q08AM6,Q10713,Q01968 6
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.6944203745212926 1.4244486452830518 0.1543166410496423 1.0 0.479152181790544 4 P16104 1
Insulin receptor recycling 0.6145747247542139 1.3922672913013134 0.1638414723978778 1.0 0.4989396562461236 9 Q9Y487,Q93050 2
Cell cycle mitotic 0.2770608379401652 1.3804648601637977 0.1674435618828458 1.0 0.5077204998722342 264 P04183,Q09472,Q14997,Q9UQE7,Q9UJX5,Q86XL3,Q8N1F7,P62191,Q8WUX9,Q96FJ2,Q9BRT9,P55735,P42695,Q13409,P04350,Q71F23,Q99996,P23258,O95235,O00139,P00374,Q92530,P25205,Q96EA4,Q99986,P28340,Q9BZD4,Q00534,Q9UNM6,O43242,Q15008,O95067,Q13257,P15927,Q14674,Q16763,P55036,Q9NR33,Q9UJX4,P51530,Q9H1A4,Q9Y2S7,Q13561,P24941,O00231,O60763,P12270,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P17252,Q9UIS9,P67870,P49721,P04818,Q08379,Q86XI2,O75122,P30622,P20700,P33992,P27361,P02545,Q96EE3,Q9BSJ2,O75330,O15504,Q9BTX1 72
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5060812834508113 1.372848154378772 0.1697995570306374 1.0 0.5104824980516823 17 Q15293,O43852,Q07065,Q06481,Q02818 5
Sema4d in semaphorin signaling 0.6197558030906101 1.3515463497238875 0.1765204830202673 1.0 0.5242066143817249 8 P35580,Q13464,O75116,P35579,P63000,Q9NWH9 6
Signaling by scf kit 0.6063373547513258 1.351327707536435 0.1765904801455775 1.0 0.5242066143817249 9 P17252,P63000 2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6174641751180484 1.3404735180195049 0.1800914482690023 1.0 0.5323623774144358 8 Q9H1A4,Q9UJX4,Q9UJX2,Q9UJX5 4
Assembly and cell surface presentation of nmda receptors 0.5754285277118327 1.335384199774338 0.1817506333483969 1.0 0.5350284269193435 11 Q15334,Q13555,P04350,Q92796,Q13557,Q12959 6
Carboxyterminal post translational modifications of tubulin 0.6514122156587931 1.3328210326553875 0.1825905417953703 1.0 0.5363834419061504 6 P04350 1
Rhoa gtpase cycle 0.3690574432148314 1.3313716265955386 0.1830667606546907 1.0 0.5366666655707013 47 O15173,Q86UP2,P30519,Q14254,Q13017,P28288,P49257,Q9P0I2,P51572,Q16512,Q96CS3,Q96HY6 12
Raf independent mapk1 3 activation 0.632114918409947 1.324990380313556 0.1851743419301921 1.0 0.5371552143305452 7 P36507 1
Apc c cdc20 mediated degradation of cyclin b 0.5873069512709702 1.324298980742962 0.1854037689090546 1.0 0.5371552143305452 10 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4
Pre notch expression and processing 0.5586295816826774 1.3224140677674987 0.186030306920617 1.0 0.5371552143305452 12 Q09472,Q9HCE1,P16615 3
Signaling by insulin receptor 0.5190145892807728 1.3209047759320396 0.1865331171097111 1.0 0.5371552143305452 15 Q9Y487,Q93050 2
Inactivation of cdc42 and rac1 0.6122498980804549 1.3205471726651812 0.1866523971824765 1.0 0.5371552143305452 3 P63000 1
Interleukin 4 and interleukin 13 signaling 0.5438277824294979 1.3203274998920418 0.1867256978938345 1.0 0.5371552143305452 13 P09601 1
Defective ripk1 mediated regulated necrosis 0.6120071684587712 1.3194014519433428 0.1870349366246484 1.0 0.5371552143305452 3 Q14790,Q12933 2
Fcgamma receptor fcgr dependent phagocytosis 0.409624938321452 1.309436650665832 0.1903864833498483 1.0 0.542371171317209 30 Q14185,Q9Y4I1,P19174,P35240,P61160,Q8IV08,Q9Y2A7,P27361,Q9UQB8,Q16512,Q96F07,P59998,P63000 13
Factors involved in megakaryocyte development and platelet production 0.3584613645068727 1.2920731725854049 0.1963318054518028 1.0 0.5504302402845187 50 Q96N67,P04350,O00139,O95235,Q14185,P52907,P47755,O95140,P33176,P24941,Q9H0B6,Q99661,Q9NRW7,P17252,Q9BW19,Q9NS87,Q9Y496,O60333,P63000 19
Cell surface interactions at the vascular wall 0.5012167697964549 1.276266438719933 0.2018613497291166 1.0 0.562583998357479 16 P53985,P14174,P35613 3
Recycling of eif2 gdp 0.599219075063677 1.2522752110298483 0.2104695983754863 1.0 0.5763077301869296 8 P20042,Q13144 2
Metabolism of steroids 0.3568111266061973 1.2492181052771023 0.2115853116423707 1.0 0.5763077301869296 49 P37268,Q13907,Q15125,Q15126,P04062,Q16850,P38435,Q15800,Q15392 9
Pyroptosis 0.6424495149321838 1.2444728758956611 0.2133255761222787 1.0 0.5775927654219332 5 P09429 1
Transferrin endocytosis and recycling 0.5716756747790578 1.2441735036901689 0.2134357132475399 1.0 0.5775927654219332 10 Q9Y487,Q93050 2
Cellular response to chemical stress 0.3273631940968227 1.2421105945529167 0.2141957601423163 1.0 0.5775927654219332 77 Q14997,P30519,Q8TCT9,P14854,P09601,P55036,P53004 7
Complex i biogenesis 0.414958675544625 1.230733202417686 0.2184226657219719 1.0 0.5867513814926736 27 Q9P0J0,P51970,O75380,O43676,Q86Y39,Q9BQ95,O75306 7
Golgi cisternae pericentriolar stack reorganization 0.5549383559961865 1.2270545916478697 0.2198020731440226 1.0 0.587728391827496 11 P27361,Q08379,O95067 3
Pp2a mediated dephosphorylation of key metabolic factors 0.5890083632019006 1.210877023002842 0.2259425398931591 1.0 0.5989808796792381 3 P30154,P30153 2
Nrif signals cell death from the nucleus 0.530904747685882 1.1976697352517869 0.2310456159874623 1.0 0.605691011855815 2 Q92542 1
The phototransduction cascade 0.6021300696715887 1.1849112860865738 0.2360525246020874 1.0 0.6176707727087956 7 P50579,P49354,P53582 3
Josephin domain dubs 0.5821385902030949 1.1785033285721618 0.2385960061360728 1.0 0.6231721934755469 3 P54725,P55072 2
Synthesis of pc 0.6371478455174755 1.176597747775196 0.2393560971583528 1.0 0.6240039949903183 4 P35790,P67870 2
Nuclear envelope ne reassembly 0.3450978975546493 1.173600524647949 0.2405550709720796 1.0 0.6259747979439199 51 Q86XL3,O95067,Q8WUX9,P55735,Q96EE3,Q9BTX1 6
Regulation of pten localization 0.5216482532099206 1.1497812169256043 0.2502339933504878 1.0 0.6440448681315833 2 P98170 1
Formation of atp by chemiosmotic coupling 0.5501786648836053 1.134072843311437 0.2567639938716466 1.0 0.657260006051878 10 P18859,P06576,P56134,O75964,P25705 5
Phosphorylation of the apc c 0.5369475858415117 1.1320212338249205 0.2576255074186853 1.0 0.65827277031212 11 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4
Fceri mediated mapk activation 0.5604142998410184 1.1229887269039631 0.2614422822438129 1.0 0.6635700409299558 9 P27361,P63000,Q13177,Q16512 4
Metabolism of vitamins and cofactors 0.3469904488238349 1.122740526778522 0.2615477105902095 1.0 0.6635700409299558 48 Q9H2D1,P43490 2
Dap12 signaling 0.5699744989149291 1.1212807626759138 0.2621683714759055 1.0 0.6638779729309221 3 P63000 1
Oncogenic mapk signaling 0.3916225241257266 1.117642474094404 0.2637197207173785 1.0 0.6666117448544827 29 Q9NRY5,P36507,Q13555,P27361,Q96PU8,Q99996 6
Signaling by leptin 0.5138847417139507 1.1097008790231055 0.2671279439959171 1.0 0.6716223930004108 2 P40763 1
Synthesis of udp n acetyl glucosamine 0.6197918612328908 1.1017128900640334 0.2705865112511729 1.0 0.6782951712065127 4 Q9UJ70,Q06210 2
Ngf stimulated transcription 0.6194745200967782 1.1003464010935986 0.271181222182379 1.0 0.6782951712065127 4 Q09472 1
Cyclin d associated events in g1 0.5435314866538676 1.1001018216959908 0.2712877602209462 1.0 0.6782951712065127 10 Q00534 1
Signaling by rho gtpases miro gtpases and rhobtb3 0.2663409828281365 1.099151247438243 0.271702099718957 1.0 0.6782951712065127 258 P35580,P30519,P34897,P49257,Q9UQB8,Q16512,Q96CS3,P67936,Q14185,Q15345,O75323,Q96F07,O15173,O43663,P28288,P08670,Q92974,Q9NNW5,Q5VTR2,P30622,P27361,Q9P2R3,Q13505,Q96N67,Q8N684,Q86XL3,Q9UNZ2,Q9Y2A7,Q03001,P55735,Q13409,P12814,Q9BZD4,Q13177,Q07065,Q16543,Q92888,Q9NZM3,Q13464,Q01082,P06753,Q9H0B6,P35579,Q99570,Q9UEY8,Q96EE3,P59998,P35221,P35240,Q13017,P51151,Q96FJ2,Q14344,P31948,P04350,Q71F23,Q68EM7,Q96HY6,Q96EA4,Q13257,O15498,O43237,O95140,P33176,Q96AC1,Q92747,Q99661,Q9H8V3,P17252,P51648,O94887,Q9P0I2,P63000,Q13813,Q01968,P51572,O00139,Q14254,P61160,Q13576,P12277,P16104,Q86UP2,O75122,P20700,Q5JTV8 86
Smooth muscle contraction 0.5297787447629617 1.0942314390177388 0.2738534861618809 1.0 0.6797471227518219 11 Q05682,P67936,Q16512,P06753 4
Extracellular matrix organization 0.381789111722336 1.0942168331974045 0.2738598904354945 1.0 0.6797471227518219 31 Q32P28,Q03001,O60568,P35613 4
Rho gtpases activate iqgaps 0.5166161524920717 1.0932063423067526 0.2743032130077834 1.0 0.6797471227518219 12 P30622,Q13576,P63000,P04350 4
Kinesins 0.4259304384255919 1.0911545494529078 0.2752048832524214 1.0 0.6797471227518219 22 Q9Y496,P33176,Q9H0B6,Q99661,P04350,O00139,Q9BW19,O95235,Q9NS87 9
Mitotic g2 g2 m phases 0.3151851366023671 1.0899003442895596 0.2757570449415731 1.0 0.6797471227518219 92 Q09472,Q14997,P24941,O00231,P17252,O95067,P61289,P55036,Q13409,P04350,P49721,Q99996,P23258,Q9UIS9,Q13561,O75330 16
Synthesis of dna 0.3141045999353485 1.0882068550176904 0.2765037991819166 1.0 0.6797471227518219 86 Q14997,Q9UJX5,P62191,Q9BRT9,Q92530,P25205,P28340,Q9UNM6,O43242,P15927,Q16763,P55036,Q9NR33,Q9H1A4,Q9UJX4,P51530,Q9Y2S7,P24941,O00231,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 27
Activation of the pre replicative complex 0.4253439065646966 1.0870188510113823 0.2770284787193446 1.0 0.6797471227518219 22 P24941,Q99741,P15927,O43913,P33992,P35244,P09884,Q9NR33,P33991,Q9UBD5,Q14566,P25205 12
Cytochrome c mediated apoptotic response 0.596473427557717 1.0847575119222252 0.2780290681623418 1.0 0.6797471227518219 6 Q9NR28,Q96GX9 2
Class i peroxisomal membrane protein import 0.5805242874959078 1.084257959483658 0.2782504397561549 1.0 0.6797471227518219 7 O75381,P40855,P51648 3
Advanced glycosylation endproduct receptor signaling 0.5640720913504367 1.0826761393121134 0.2789521985259475 1.0 0.6797471227518219 8 P27361,P52907,P09429,P47755 4
Slc transporter disorders 0.3754875961508347 1.0814439025429594 0.279499701570282 1.0 0.6797471227518219 33 P55735,Q9BTX1,P53985,P35613 4
Rho gtpases activate ktn1 0.563057757344323 1.0777987183293378 0.2811235916506627 1.0 0.6813510034346251 8 P63000,Q9H0B6 2
Tnfr1 induced proapoptotic signaling 0.6121900209142539 1.0690127282157058 0.2850639340929441 1.0 0.6858819848164943 4 Q6GQQ9,Q14790,Q12933 3
Caspase activation via death receptors in the presence of ligand 0.6121900209142521 1.0690127282156974 0.2850639340929479 1.0 0.6858819848164943 4 P49327,Q14790,Q12933 3
Regulation by c flip 0.6121900209142521 1.0690127282156974 0.2850639340929479 1.0 0.6858819848164943 4 P49327,Q14790,Q12933 3
Hdms demethylate histones 0.549514876463407 1.0689908195125033 0.2850738061694358 1.0 0.6858819848164943 9 Q8IUF8,Q6NYC1 2
Activation of atr in response to replication stress 0.4226770146694594 1.0682226188782669 0.2854201040849955 1.0 0.6858819848164943 22 P24941,P15927,P33992,O14757,P35244,Q9UBD5,Q14566,P25205 8
Aggrephagy 0.4648821924006294 1.0541615994836202 0.2918089377519046 1.0 0.69532214003953 16 Q13409,P08670,Q96FJ2 3
Base excision repair ap site formation 0.5978737649867162 1.047957043762347 0.2946583985494184 1.0 0.7005186727825565 5 P13051,P16104 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5325225984010521 1.0439723470869189 0.2964981837579232 1.0 0.7029394859898416 10 Q9UJX4,Q9H1A4,Q9UJX2,Q9UJX5 4
Recycling pathway of l1 0.4238567618577337 1.0396388515456336 0.2985077195806986 1.0 0.7065182709673822 21 P15311,P35241,P26038,P04350 4
Processive synthesis on the lagging strand 0.4790569955410275 1.0291701637743558 0.3033997200266927 1.0 0.7130107035244306 14 P51530,P28340,P15927,P35244 4
Sema4d induced cell migration and growth cone collapse 0.583909324466934 1.0283848924712038 0.3037688121667248 1.0 0.7130107035244306 6 P35579,P35580,O75116,Q13464 4
Oncogene induced senescence 0.5527219493872664 1.0281899814736963 0.3038604701569345 1.0 0.7130107035244306 8 Q9HCE1,Q00534 2
Downregulation of smad2 3 smad4 transcriptional activity 0.5525365155122658 1.027301634244326 0.3042784530964131 1.0 0.7130107035244306 8 Q96PU5,Q13485 2
Apoptotic factor mediated response 0.56753014205984 1.0239971872715106 0.3058366034436395 1.0 0.7154753653408322 7 Q9NR28,Q96GX9 2
Ncam signaling for neurite out growth 0.5899754676962838 1.0133775941648768 0.3108798373570733 1.0 0.7226100993256723 5 P27361,Q13813 2
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4480085430052516 1.008392166887725 0.3132662318857186 1.0 0.7244602056538797 17 P61758,Q9NQP4,P04350 3
Purine salvage 0.5789610315700743 1.0062542501067135 0.3142932817828117 1.0 0.7256477241161975 6 P55263 1
Cyclin a b1 b2 associated events during g2 m transition 0.4989125569991895 0.997178537496551 0.3186778567570907 1.0 0.7321818074760474 12 O95067 1
M phase 0.2626673076790468 0.9916389230256712 0.3213736949665735 1.0 0.7353873338758135 198 Q14997,Q9UQE7,Q9UJX5,Q86XL3,Q8N1F7,P62191,Q8WUX9,Q96FJ2,P55735,P42695,Q13409,P04350,Q71F23,Q99996,P23258,O95235,O00139,Q92530,Q96EA4,Q99986,Q9BZD4,Q9UNM6,O43242,Q15008,O95067,Q13257,Q14674,Q16763,P55036,Q9UJX4,Q9H1A4,Q13561,O00231,O60763,P12270,P16104,P61289,P17252,Q9UJX2,Q9UIS9,P67870,P49721,Q08379,Q86XI2,O75122,P30622,P20700,P27361,P02545,Q96EE3,Q9BSJ2,O15504,Q9BTX1 53
Cd28 dependent vav1 pathway 0.5829215891945903 0.9825922156936217 0.3258081771282388 1.0 0.7432869282138892 5 P63000,Q16512 2
Respiratory electron transport 0.3256192336412973 0.9764235525126922 0.3288546146601199 1.0 0.7482633985744757 52 Q9P0J0,P51970,O75380,P14854,O43676,Q9UDW1,P22695,Q86Y39,Q9BQ95,O75306 10
Srp dependent cotranslational protein targeting to membrane 0.3061762526618655 0.9696419478170312 0.3322249961296744 1.0 0.7502144069846669 90 P04843,P62841,P67812,P09132,P61247,P62854,Q9UHB9,P04844,P61254,P62081,P46778,P18621,P50914,Q9Y5M8,P08865,P51571,P84098,P25398,P49458,P62917,P62266,P62899,P62750,P46782,P61513,O76094,Q02543,P62753,P15880,P43307,P46776,P27635 32
Mitotic g1 phase and g1 s transition 0.3055706360260355 0.969217027748692 0.332436917001258 1.0 0.7502144069846669 78 P04183,P62191,Q92530,P00374,P25205,Q00534,Q9UNM6,O43242,P15927,P55036,Q9NR33,P24941,O00231,P35244,P61289,P33991,Q9UBD5,Q14566,P49721,P04818,P33992 21
Meiotic recombination 0.4684227571566248 0.9678959862811112 0.3330963190807838 1.0 0.7502144069846669 14 P16104,P15927,P35244,P24941 4
Ire1alpha activates chaperones 0.4029848980425396 0.9672308860013278 0.3334286253265186 1.0 0.7502144069846669 23 P49748,O14773,Q969H8,P02545,P43307,Q13217,O95070,Q9UBS4,Q06210,Q9Y5M8 10
Hemostasis 0.3000344346502145 0.9632906004376404 0.3354017090303041 1.0 0.7526139607797081 124 Q96N67,P55145,P04350,P35613,O00139,Q8NBX0,O95235,P12814,Q14185,P07602,O43852,P47755,Q12846,Q9UNN8,P14174,P24941,Q9H0B6,P42785,Q06481,P17252,Q9BW19,Q9NS87,Q8NCG7,P27361,P53985,P16615,P63000 27
Mrna splicing minor pathway 0.3641275736996986 0.962974411611486 0.3355603646788507 1.0 0.7526139607797081 32 P55769,Q9BWJ5,Q09161 3
Rrna processing in the mitochondrion 0.5674310700301406 0.9548811715732656 0.3396377923754867 1.0 0.7566038943287139 6 O15091 1
Role of abl in robo slit signaling 0.585082151031 0.9531603860446712 0.3405088141546262 1.0 0.7566038943287139 4 O75122 1
Response to elevated platelet cytosolic ca2 0.3705027993051055 0.9452162842860956 0.3445484674699868 1.0 0.7594060527254141 29 P07602,P17252,O43852,Q12846,Q06481,Q8NBX0 6
Signaling by notch3 0.5233282617423585 0.9401287286749124 0.3471515342525053 1.0 0.7594060527254141 9 P67809 1
Hdr through mmej alt nhej 0.5340278325510283 0.939010787057755 0.3477252060250126 1.0 0.7594060527254141 8 Q9UGN5,P39748,P18887,P49959,Q92878,P09874 6
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.4872847125022886 0.9345179130283086 0.3500368002177119 1.0 0.7620077504867552 12 Q96PU5,Q13485,P27361 3
Interleukin 21 signaling 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.7620077504867552 2 P40763 1
Interleukin 9 signaling 0.4792475365780896 0.932508812552133 0.3510736345130061 1.0 0.7620077504867552 2 P40763 1
Traf6 mediated nf kb activation 0.532149845823838 0.9301008580159452 0.3523188665829888 1.0 0.762607278902535 8 O15111 1
Parasite infection 0.4022751750175736 0.9251035329805848 0.3549120555038831 1.0 0.7656347090488349 22 Q14185,Q9Y4I1,P61160,Q9Y2A7,P27361,Q96F07,Q9UQB8,P59998,P63000 9
Acyl chain remodelling of pg 0.4774559570020912 0.92344620331812 0.3557747232030026 1.0 0.7663257376308578 2 Q8NF37 1
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5429625402152868 0.9109997428065304 0.3622955091848099 1.0 0.7681193983510994 7 O15111 1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3777308138196653 0.9096669490056416 0.3629981795289327 1.0 0.7681193983510994 26 P26038,P14174,Q00169,Q13126 4
Signaling by mapk mutants 0.4723798148701145 0.8978406261446009 0.3692705222416939 1.0 0.7769089912126841 2 P28482 1
Interleukin 12 signaling 0.3679619091404618 0.8915721429846665 0.3726223070030241 1.0 0.7811799996962508 28 P26038,P14174,Q00169,Q13126 4
The citric acid tca cycle and respiratory electron transport 0.3007866507072792 0.8900484300666098 0.3734398818778812 1.0 0.7817341527310314 93 O75390,P18859,Q9P0J0,P51970,O75380,P06576,P14854,O43676,P22695,O75964,Q9UDW1,P21796,P56134,Q86Y39,P35613,P53985,Q9BQ95,O75306 18
Activation of nmda receptors and postsynaptic events 0.3809573649996067 0.8888134260503245 0.3741033590495761 1.0 0.7819645655873536 25 P54646,Q13555,P54619,P04350,P17252,P63000,Q12959 7
Ras processing 0.5605085380763504 0.8855506090201081 0.375859736689041 1.0 0.7821354511129306 5 P49354 1
Pyruvate metabolism 0.4455720475774975 0.8852326249293347 0.3760311796875681 1.0 0.7821354511129306 15 P21796,P35613 2
Orc1 removal from chromatin 0.3182785974453159 0.8835248641652548 0.3769527545703508 1.0 0.7821354511129306 51 Q14997,Q9UNM6,P24941,O00231,O43242,P33992,P62191,P61289,P55036,P33991,Q9UBD5,Q14566,Q92530,P49721,P25205 15
Abc family proteins mediated transport 0.3201239601085817 0.8816789234602993 0.3779504617820484 1.0 0.7830557221378802 50 Q14997,Q9UNM6,O00231,P28288,O43242,P62191,Q9NRK6,P61289,P40855,P55036,P49721,P20042,P08183,Q92530 14
Signaling by vegf 0.361652697878543 0.8736101768078486 0.3823305821561513 1.0 0.790970882264483 29 Q14185,Q13464,Q13177,P19174,P42345,Q9Y2A7,Q9UQB8,Q16512,Q96F07,P17252,P63000 11
Pi3k akt signaling in cancer 0.4631846452622384 0.869055890089842 0.3848165616314365 1.0 0.7930386655933551 13 P49815,O15111,P42345,Q9NWH9,P63000 5
Dna strand elongation 0.3565874921343162 0.8672642694027698 0.3857972292207707 1.0 0.7930386655933551 30 P28340,P15927,P33992,P35244,P51530,Q14566,Q9BRT9,Q9Y2S7,P25205 9
Epha mediated growth cone collapse 0.5160482055881825 0.8541732964910764 0.3930089766734501 1.0 0.8007607110538806 8 P35579,P35580,O75116,Q13464 4
Signal transduction by l1 0.4942029996072979 0.8508391144854661 0.3948587303440531 1.0 0.8007607110538806 10 P36507,P27361,P63000,Q16512 4
Copi dependent golgi to er retrograde traffic 0.3207679875214534 0.8499390179523298 0.3953589912992412 1.0 0.8007607110538806 48 Q9Y496,P24390,P49755,P48444,P61923,P33176,Q9H0B6,Q6NUQ1,Q99747,Q9Y3B3,Q99661,P04350,O00139,Q9P2W9,Q9BW19,O95235,Q9NS87 17
Senescence associated secretory phenotype sasp 0.391401527328337 0.8495715701712359 0.3955633236486968 1.0 0.8007607110538806 22 Q9H1A4,Q9UJX5,P24941,Q00534,P16104,P27361,Q9UJX4,Q9UJX2 8
Signaling by ntrk2 trkb 0.5517710676059121 0.8481177616338929 0.3963723908322512 1.0 0.8012506269613318 5 P63000 1
Gpcr ligand binding 0.4919993464396814 0.8398863764551981 0.400972096876194 1.0 0.8050910380504054 10 P07602 1
Vegfr2 mediated cell proliferation 0.5091172087204333 0.8393897123375104 0.401250654960708 1.0 0.8050910380504054 3 P17252 1
Role of phospholipids in phagocytosis 0.5091172087204332 0.8393897123375104 0.401250654960708 1.0 0.8050910380504054 3 Q8IV08 1
Ticam1 traf6 dependent induction of tak1 complex 0.4601373544341569 0.8365769505380933 0.4028304061582708 1.0 0.8050910380504054 2 Q15750 1
Irak2 mediated activation of tak1 complex 0.4601373544341569 0.8365769505380933 0.4028304061582708 1.0 0.8050910380504054 2 Q15750 1
Alpha protein kinase 1 signaling pathway 0.4601373544341569 0.8365769505380933 0.4028304061582708 1.0 0.8050910380504054 2 Q15750 1
Nervous system development 0.2568342933558534 0.833814189679451 0.4043856980221858 1.0 0.8056409847108275 217 P35580,Q14997,P62841,P61247,P62191,P62854,P50570,Q16512,P04350,Q92530,Q12959,Q14185,Q13177,Q9UNM6,P15311,P61160,O43242,Q15008,P61254,P62081,P46778,Q16850,P55036,P18621,P50914,Q00169,Q9NWH9,Q13464,Q01082,P19174,Q09161,A0MZ66,P36507,O00231,P25398,P84098,P08865,P62917,P61289,O43347,P35579,P17252,P62899,P62266,P62750,P67870,P49721,P46782,P35241,O94887,O75122,P46939,P61513,Q02543,P62753,P15880,P27361,P46776,P59998,P27635,P26038,P63000,Q13813 63
Dna replication 0.2961041679425991 0.8281131026176444 0.4076064498102347 1.0 0.8066497389101704 92 Q14997,Q9UJX5,P62191,Q9BRT9,Q92530,P25205,P28340,Q9UNM6,O43242,P15927,Q16763,P55036,Q9NR33,Q9H1A4,Q9UJX4,P51530,Q9Y2S7,P24941,O00231,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 28
Initiation of nuclear envelope ne reformation 0.4095955217883195 0.8247491107385568 0.4095140435751347 1.0 0.8092913896107209 18 O95067 1
Formation of xylulose 5 phosphate 0.502986857825553 0.8116754035973378 0.4169779115069281 1.0 0.814151740173113 3 Q7Z4W1,Q00796 2
Leishmania infection 0.3256905116682922 0.8058371723450172 0.4203367414182035 1.0 0.8159089772528707 41 Q14185,Q9Y4I1,P19174,P61160,P09601,Q9Y2A7,P27361,Q9UQB8,Q96F07,P59998,P17252,P63000 12
Interleukin 12 family signaling 0.3473032233220888 0.8050342437945744 0.4207999192330545 1.0 0.8159089772528707 31 P26038,P14174,Q00169,Q13126 4
Pcna dependent long patch base excision repair 0.3972266677832762 0.8024712336302426 0.4222804219906106 1.0 0.817372926401004 19 P28340,P15927,P35244,Q9NR33,P27695 5
Cardiac conduction 0.4492444788970781 0.7929293218560315 0.4278190026105177 1.0 0.8266277844762149 13 P17252,Q99996,P16615 3
Toll like receptor 9 tlr9 cascade 0.3622011261201575 0.7918306290318051 0.4284594404242503 1.0 0.8266277844762149 26 Q15075,P09429,O15111 3
Mitotic prometaphase 0.2937781037953483 0.7912179483452695 0.428816819547817 1.0 0.8266277844762149 95 Q9BZD4,Q9UQE7,O00139,O75122,P17252,O95067,Q96FJ2,P55735,Q96EE3,Q13409,P04350,P23258,Q99996,Q9UIS9,Q13561 15
Rnd3 gtpase cycle 0.4193434987674743 0.7803125816845861 0.4352069088781394 1.0 0.8318951482183156 16 Q86UP2,P12277,Q14254,Q13017,Q03001,Q07065,Q9NNW5 7
Constitutive signaling by aberrant pi3k in cancer 0.5259010059369047 0.7730763843573719 0.4394771763247067 1.0 0.834852240898701 6 O43815,Q9NWH9,P63000 3
Assembly of the orc complex at the origin of replication 0.523929008439697 0.7646112450161512 0.4445030710714928 1.0 0.8400337537112433 6 Q9UBD5 1
Cellular response to starvation 0.2910060744060002 0.764299503569985 0.4446887811578273 1.0 0.8400337537112433 90 P62841,P61247,P62854,P55735,Q9UI12,Q9Y5K8,P42345,P61254,P62081,P46778,P18621,P50914,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P61513,Q9NXC5,P62753,P15880,Q02543,Q96EE3,P46776,P27635,P20042 29
Nr1h2 and nr1h3 mediated signaling 0.4855873077310736 0.7582738651732427 0.4482870495771633 1.0 0.8434376589146667 9 Q09472,Q9HCE1 2
Signaling by gpcr 0.3116906174867415 0.7572862984874779 0.4488783577521793 1.0 0.8434376589146667 48 Q86YR5,Q13464,P07602,Q8NCG7,O75116,Q13555,Q14344,Q92974,P42892,P27361,P62136,Q16512,Q92888,Q9H8V3,P17252,Q13557,Q9NZJ7 17
L1cam interactions 0.3181009069810578 0.7532564679173995 0.4512958125698025 1.0 0.8446105737233522 43 P35241,Q01082,A0MZ66,P15311,P36507,P50570,P27361,P04350,Q16512,P26038,P63000,Q13813,Q12959 13
Unwinding of dna 0.4734414647026035 0.748592014711459 0.4541031465158154 1.0 0.8469528012809177 10 Q14566,Q9BRT9,P33992,P25205 4
Dna replication pre initiation 0.2965596851154723 0.748190065261984 0.45434552255551 1.0 0.8469528012809177 63 Q14997,P62191,Q92530,P25205,Q9UNM6,P15927,O43242,P55036,Q9NR33,P24941,O00231,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,P49721,P33992 19
Rho gtpases activate nadph oxidases 0.5057591228962429 0.74367521682209 0.4570729862733773 1.0 0.8498777560987437 7 P17252,P27361,P63000 3
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4921848116646035 0.7436015792940519 0.4571175475124169 1.0 0.8498777560987437 8 Q15334,Q13555,P27361,Q13557,Q12959 5
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4383162229079672 0.7340467666975645 0.4629202357818505 1.0 0.8584072088710692 13 O15111 1
Global genome nucleotide excision repair gg ner 0.3133673764376901 0.7306650900117837 0.4649837438309596 1.0 0.8599764791009764 45 Q07864,Q92759,Q9UNS2,P28340,P15927,Q86WJ1,Q9NR33,P09874,Q13620,P40938,Q9Y2S7,P25490,P35244,P19447,P18074,Q96EZ8,P18887,P35251,Q9UBW8,P54725 20
Mitochondrial translation 0.2997457031783601 0.7239853518748068 0.4690747279987555 1.0 0.864149401124174 54 Q92665,P46199,P82933,Q9H2W6,Q16540,Q96EY7,Q7Z7H8,Q9Y3D3 8
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4779912570682332 0.7225040653002495 0.4699846268544689 1.0 0.8646982783142769 9 Q7L5D6,O43681,P09601,P51648 4
Generation of second messenger molecules 0.528570123301029 0.7183622645494454 0.4725339476990431 1.0 0.867130478050322 4 Q13177,Q16512 2
Sealing of the nuclear envelope ne by escrt iii 0.4551728655282702 0.7095140492885834 0.478005536192386 1.0 0.8694936104762699 11 Q8WUX9 1
Egr2 and sox10 mediated initiation of schwann cell myelination 0.5104584434472538 0.7073119896839603 0.4793726162902878 1.0 0.8700551962386309 6 Q16850,P46939 2
Interleukin 20 family signaling 0.4793906810035702 0.7068342363115161 0.4796694960154943 1.0 0.8700551962386309 3 P40763,Q06124 2
Processing of smdt1 0.4639193902907736 0.7025188120564373 0.4823556740963237 1.0 0.8726870262459737 10 Q9UJZ1,Q10713,Q96TA2 3
Dual incision in gg ner 0.3550419527029562 0.6987101846651812 0.4847331677864517 1.0 0.8747483602583094 25 P18074,P28340,P15927,P35244,Q86WJ1,Q92759,P19447,Q9NR33,P35251,P09874,Q07864,Q13620,Q9Y2S7 13
Energy dependent regulation of mtor by lkb1 ampk 0.4940832835979857 0.6925307789806786 0.4886040637606308 1.0 0.880609109813484 7 P54619,P42345,P54646 3
S phase 0.2864863884280132 0.6878129242122406 0.4915705962756758 1.0 0.8827344814343369 99 Q14997,Q9UQE7,Q9UJX5,P62191,Q9BRT9,Q92530,P25205,P28340,Q9UNM6,O43242,P15927,Q16763,P55036,Q9NR33,Q9H1A4,Q9UJX4,P51530,Q9Y2S7,P24941,O00231,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,P33992 28
Nephrin family interactions 0.492851744161275 0.6871836510838253 0.4919670055029073 1.0 0.8827344814343369 7 Q13813,Q01082,P12814 3
Linoleic acid la metabolism 0.4293819050462819 0.6866834694795836 0.4922822161148319 1.0 0.8827344814343369 2 O95864 1
Nucleotide excision repair 0.2924176189903731 0.6809970581372988 0.4958733519120151 1.0 0.8843513492598782 59 P18074,Q09472,P28340,P25490,Q96EZ8,P15927,P35244,Q86WJ1,Q9HCS7,Q9NR33,Q9UBW8,P55199,Q9Y2S7 13
Vesicle mediated transport 0.2492086542195099 0.6787821363734894 0.4972759140842324 1.0 0.8849507136033002 248 Q10472,Q9UJW0,P24390,Q8WUX9,Q96FJ2,Q14789,P50570,P55735,P54619,P33908,Q13409,P04350,Q14108,O00139,Q8WTV0,Q7Z392,P61160,P54646,Q13561,Q9UKS6,Q9H0B6,Q8IWJ2,Q9UPT5,Q9Y2L5,Q4KMP7,Q9P2W9,Q08379,Q8TBA6,P51159,Q9UJ41,Q9Y3B3,Q9UNF0,Q9UBW8,P59998,P63000,Q13813,Q01968 37
Recognition and association of dna glycosylase with site containing an affected purine 0.5169570795538736 0.6718613059103327 0.5016719957770885 1.0 0.8905308166244047 4 P16104 1
Base excision repair 0.330571704735991 0.6686325329638514 0.5037299144393803 1.0 0.8930619436673078 31 P28340,P13051,P15927,P16104,P35244,Q9NR33,P27695 7
Met activates rap1 and rac1 0.5085184715795039 0.6675743264682059 0.5044053503621702 1.0 0.8931387970698577 5 Q9NWH9,P63000 2
Apc cdc20 mediated degradation of nek2a 0.445719422072912 0.6628060723318472 0.5074547640762652 1.0 0.8951730107862207 11 Q9H1A4,Q9UJX5,Q16763,Q9UJX4,Q9UJX2 5
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.445719422072912 0.6628060723318472 0.5074547640762652 1.0 0.8951730107862207 11 Q9H1A4,Q9UJX5,Q16763,Q9UJX4,Q9UJX2 5
Interactions of vpr with host cellular proteins 0.3218673625397498 0.6594797768842792 0.5095877281813976 1.0 0.8978147879305672 35 P55735,Q9BTX1,P17096,P12235 4
Synaptic adhesion like molecules 0.4861895323179202 0.6584278674682262 0.5102632333673434 1.0 0.8978853658132704 7 Q12959,Q15334,O75955,Q14254 4
Platelet activation signaling and aggregation 0.2953719254832497 0.6534334615662846 0.5134768725711707 1.0 0.9003606690695268 52 P07602,P17252,O43852,Q8NCG7,Q06481,Q8NBX0,P63000 7
Cd209 dc sign signaling 0.4849874340787517 0.6532710878340039 0.5135815281458165 1.0 0.9003606690695268 7 P17252,Q09472,Q16512 3
Regulation of hmox1 expression and activity 0.303326077447476 0.6456810666672699 0.5184859246678708 1.0 0.9066661430164432 46 Q14997,Q9UNM6,O00231,P67870,Q8TCT9,O43242,P62191,P09601,P61289,P55036,P49721,Q92530 12
Mapk6 mapk4 signaling 0.2955448269100328 0.6447283170932487 0.5191032623498248 1.0 0.9066661430164432 51 Q16181,Q14997,Q9UNM6,Q13177,O00231,O43242,P62191,Q9HCE1,P61289,P55036,Q16512,P49721,P17252,P63000,Q92530 15
Visual phototransduction 0.4514223160779367 0.6430172121159914 0.52021293144097 1.0 0.9071597626428552 10 P50579,P49354,P53582 3
Phosphorylation of emi1 0.4644563918757307 0.6423131170680662 0.5206698991531178 1.0 0.9071597626428552 3 P06493,P53350 2
Nuclear pore complex npc disassembly 0.3254811695065014 0.6406626949711794 0.5217418565126173 1.0 0.907750332837131 32 P12270,O95067,P55735,Q96EE3,Q9BTX1 5
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.5088348799157193 0.6398137136639652 0.5222937159211518 1.0 0.907750332837131 4 O94887 1
Cdc42 gtpase cycle 0.3276967218728149 0.6343627567369956 0.5258441091934851 1.0 0.9101349276459704 30 Q13576,Q86UP2,Q9Y5S2,Q96N67,Q13177,Q13017,P11274,O15498,Q14344,Q9UQB8,Q16512,Q9H8V3,P63167,Q68EM7,Q07960 15
Mitotic prophase 0.2870605379989706 0.6342382844572864 0.5259253260736958 1.0 0.9101349276459704 62 Q08379,Q86XI2,P20700,O60763,O95067,P12270,P16104,Q8N1F7,P27361,P55735,P02545,Q96EE3,P42695,P17252,O15504,Q9BTX1 16
Hcmv early events 0.3007648766171402 0.6337527322713179 0.5262422051569411 1.0 0.9101349276459704 47 P12270,Q96FJ2,P55735,Q96EE3,Q13409,P04350,P83916,Q9BTX1 8
Caspase mediated cleavage of cytoskeletal proteins 0.4670997504386013 0.6308635644194333 0.5281297371680278 1.0 0.9108165626802156 8 P08670 1
Synthesis of pips at the late endosome membrane 0.5058359792721369 0.6280883640118754 0.5299460552541064 1.0 0.9109656643236648 4 Q99570,Q08AM6 2
Traf6 mediated induction of tak1 complex within tlr4 complex 0.460274790919937 0.6245495866025543 0.5322667158940328 1.0 0.9121104260779276 3 Q15750,Q6SZW1 2
Trafficking of ampa receptors 0.4273321245859249 0.6217928996369695 0.5340780557774008 1.0 0.9121276210572742 12 Q15334,Q13555,P17252,Q13557,Q12959 5
Termination of translesion dna synthesis 0.3682471774003555 0.6191416082218253 0.5358230748900215 1.0 0.9121903672525304 19 P28340,P15927,P35244,Q9UBZ9,Q9NR33 5
Translation of replicase and assembly of the replication transcription complex 0.5002081123322807 0.6062497542101688 0.5443489183940491 1.0 0.9201490100615464 4 Q99570,Q8WUX9 2
Rnd1 gtpase cycle 0.4139627630772918 0.6061649610616873 0.5444052175594145 1.0 0.9201490100615464 13 Q14254,Q13017,Q03001,P31948,P51648 5
Rho gtpases activate wasps and waves 0.3805681723438792 0.5996697573644033 0.5487263472447204 1.0 0.9247288925165318 17 P61160,P27361,Q96F07,Q9UQB8,P59998,P63000 6
Interconversion of nucleotide di and triphosphates 0.3613733387224164 0.5970652180678642 0.5504638388149121 1.0 0.924857793395328 20 P00390,P04818,Q9H773,Q9Y3D8 4
Signaling by alk 0.4828079660477985 0.5931383764452967 0.5530885493096376 1.0 0.9259645973631728 6 Q09472 1
Membrane trafficking 0.245329958914898 0.5859096285033754 0.5579362465567961 1.0 0.930772038234655 242 Q10472,Q9UJW0,P24390,Q8WUX9,Q96FJ2,Q14789,P50570,P55735,P54619,P33908,Q13409,P04350,Q14108,O00139,Q7Z392,P61160,P54646,Q13561,Q9UKS6,Q9H0B6,Q8IWJ2,Q9UPT5,Q9Y2L5,Q4KMP7,Q9P2W9,Q08379,Q8TBA6,P51159,Q9UJ41,Q9Y3B3,Q9UNF0,Q9UBW8,P59998,P63000,Q13813,Q01968 36
Formation of incision complex in gg ner 0.3775486727525456 0.5822990404656379 0.5603652717046383 1.0 0.9326220599748576 17 P18074,P15927,P35244,Q86WJ1,P19447,P54725 6
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.4468339307048816 0.568465458142911 0.5697189539118579 1.0 0.9437431206066296 3 P49916,P18887 2
Resolution of abasic sites ap sites 0.3249094452064286 0.5605788347052757 0.5750846834257537 1.0 0.9480547969224744 28 Q9UGN5,P28340,P13051,P15927,P35244,P18887,P18858,P27695,P35251,Q9NR33,P09874,Q07864,P40938,P29372,Q9Y2S7 15
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3480790951695964 0.5589273355854102 0.5762113127138968 1.0 0.9480547969224744 22 P28340,P15927,P35244,Q9UBZ9,Q9NR33,Q8TAT6 6
Regulation of mecp2 expression and activity 0.3945222867376484 0.5587277501916982 0.5763475375487654 1.0 0.9480547969224744 14 P17252,Q9HCE1,Q13555 3
Glycogen synthesis 0.4739241474642853 0.5576426473769681 0.5770884283718067 1.0 0.9481697084760032 6 P46976,Q16851,Q96G03 3
Telomere c strand lagging strand synthesis 0.343496637800348 0.5550577467415713 0.5788551625629186 1.0 0.9499678800248594 23 P28340,P15927,P54132,P35244,P51530,Q9Y2S7 6
Oxidative stress induced senescence 0.3626140280061131 0.5390874138250629 0.589826539722762 1.0 0.9612743951883076 18 Q9HCE1,P16104,Q00534 3
Nuclear envelope breakdown 0.2950242691739609 0.5377497698737224 0.5907498140514644 1.0 0.9616699161920728 43 P20700,P12270,O95067,P55735,Q96EE3,P17252,Q9BTX1 7
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3397568244145715 0.5306041706058581 0.5956931049805463 1.0 0.9637374603087792 23 O15111,P09429,Q3LXA3 3
Rac1 gtpase cycle 0.294126257023356 0.5296425422903698 0.596359792362084 1.0 0.9637374603087792 43 Q14185,Q13576,Q86UP2,O94887,Q96N67,Q13177,Q13017,Q96AC1,Q9Y2A7,Q14344,O15498,Q9UQB8,Q16512,Q96F07,Q9H8V3,Q68EM7,P63000 17
Toll like receptor cascades 0.3098031766921977 0.5287207672320033 0.5969991687020111 1.0 0.9637374603087792 33 Q15075,P09429,Q9BQ95,O15111 4
Signaling by interleukins 0.2731631499722867 0.5280582335326901 0.5974589184547048 1.0 0.9637374603087792 117 P14174,Q14997,O15111,P08670,P09429,P09601,P55036,Q13126,P26038,Q00169,P49721 11
Meiosis 0.325776763544861 0.5262447571745904 0.5987181603152867 1.0 0.9637374603087792 26 Q9UQE7,P24941,P20700,P15927,P16104,P35244,P54132,P49959,P02545 9
Reproduction 0.325776763544861 0.5262447571745904 0.5987181603152867 1.0 0.9637374603087792 26 Q9UQE7,P24941,P20700,P15927,P16104,P35244,P54132,P49959,P02545 9
Transcriptional regulation of granulopoiesis 0.4345511090680345 0.5261322059316947 0.5987963533128455 1.0 0.9637374603087792 9 Q09472,P24941 2
Hiv transcription elongation 0.3302176792818174 0.5243720864348379 0.6000197673578143 1.0 0.9637374603087792 25 P18074,P55199,Q14241,Q09161 4
Myd88 independent tlr4 cascade 0.3198553577275492 0.5236280477999857 0.6005372694445663 1.0 0.9637374603087792 28 O15111 1
Estrogen dependent gene expression 0.3048865191697579 0.5186004009189757 0.6040394294427831 1.0 0.96659990238126 35 Q09472,Q9UQE7,P25490,P16104,Q99873,Q9HCE1,Q92993 7
Toll like receptor tlr1 tlr2 cascade 0.3332394609759049 0.5150392504353413 0.606525592438012 1.0 0.968516601815948 24 O15111,P09429 2
Adaptive immune system 0.2382493065001929 0.5125155844641303 0.6082902160728114 1.0 0.9686217389035684 192 Q9UJW0,Q14997,O95376,Q9UJX5,Q93034,Q96FJ2,P51572,P50570,P55735,Q16512,Q13409,P04350,O00139,Q8NEZ5,Q15345,O15111,O43242,P42345,P47755,Q12846,P55036,Q9UJX4,Q9H1A4,Q13561,O00231,Q8TDB6,O94874,Q96PU5,Q9H0B6,P61289,P17252,Q9UJX2,Q9GZZ9,P49721,P09429,P63000 36
Disorders of transmembrane transporters 0.2718321734026235 0.508696015687872 0.6109653156021246 1.0 0.9710843542697436 74 Q14997,P55735,P55036,P35613,P53985,P49721,Q9BTX1 7
Nrage signals death through jnk 0.4380084952951883 0.5063888427347177 0.6125837055071246 1.0 0.972156587550862 8 Q14344,Q92974,P63000,Q92888 4
Response of eif2ak4 gcn2 to amino acid deficiency 0.2691226222483104 0.5057731102985917 0.6130159373728366 1.0 0.972156587550862 78 P39023,P62841,P61247,P62854,P61254,P62081,P46778,P46777,P18621,P50914,P83731,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P61513,Q02543,P62753,P15880,P46776,P27635,P20042,P62913 27
Activation of gene expression by srebf srebp 0.3476643609004337 0.4951251370260947 0.6205117909754985 1.0 0.9763821940878864 19 Q15126,Q16850,Q13907,P37268 4
Intraflagellar transport 0.401267723000243 0.4951170660341897 0.6205174878208932 1.0 0.9763821940878864 12 Q9Y496,Q9BVA1,Q96FJ2,P04350,P63167 5
Protein folding 0.2970537429267526 0.4917955258094315 0.6228638997908322 1.0 0.978337168465986 38 Q9NQP4,P04062,P61758,P04350 4
Runx2 regulates bone development 0.4339380363457762 0.4896381316713977 0.6243899885151554 1.0 0.978337168465986 8 Q13485,Q9UBN7,P27361 3
Gluconeogenesis 0.3420111847406037 0.4789351751410836 0.6319847461694954 1.0 0.9835417564538382 20 Q9UBX3 1
Cargo trafficking to the periciliary membrane 0.3657763832743003 0.4782708481465038 0.6324574422763427 1.0 0.9835417564538382 16 O75695,Q10713 2
Rnd2 gtpase cycle 0.3722006693500756 0.4773769124887494 0.6330937514661799 1.0 0.9835417564538382 15 Q86UP2,Q13017,Q03001,Q07065,P51648 5
Transport of the slbp dependant mature mrna 0.3059635878585289 0.4769181865725224 0.6334203810141492 1.0 0.9835417564538382 31 Q09161,P12270,P55735,Q96EE3,Q9BTX1 5
Mastl facilitates mitotic progression 0.4645951598446463 0.4738677168687756 0.6355942416853793 1.0 0.9858338787063018 4 P06493,P30153,P30154 3
Uptake and function of diphtheria toxin 0.4631012847326029 0.4685644371917662 0.6393810020792814 1.0 0.98779625765681 4 P08238,Q16881,P13639 3
Transcription coupled nucleotide excision repair tc ner 0.2832311154159438 0.4674845408087923 0.64015324990948 1.0 0.98779625765681 47 P18074,Q09472,P28340,P15927,P35244,Q9HCS7,Q9NR33,Q9UBW8,P55199 9
Amino acids regulate mtorc1 0.3942850985045535 0.4626005870067999 0.6436506878115411 1.0 0.9909896311319584 12 Q9Y5K8,P42345,Q9NXC5,P55735,Q96EE3 5
Signaling by receptor tyrosine kinases 0.2676087505972497 0.4546174235421588 0.6493844976186611 1.0 0.9930522674623032 118 Q09472,Q96N67,Q93034,Q93050,Q9Y2A7,P50570,Q9UQB8,Q16512,Q9Y487,Q14185,Q13177,Q13043,Q9Y5K8,P42345,Q16543,Q96F07,Q9NWH9,Q13464,P19174,Q09161,P36507,O14757,P17252,P20338,P16949,P27361,Q01085,P31483,P63000 29
Apoptotic execution phase 0.2991363126462978 0.4460795881930732 0.6555397566372485 1.0 0.9981440475521898 33 P49354,P26583,P08670,P09429,P51572,O00429,Q13813 7
Smad2 smad3 smad4 heterotrimer regulates transcription 0.4437425903006547 0.4424609395136221 0.6581556896824918 1.0 0.9999720317433988 6 Q13485,P27361 2
Heme signaling 0.405090991941081 0.4353805980047172 0.6632861910281431 1.0 1.0 10 Q09472,P09601 2
Translation 0.237777265024097 0.4347983352206787 0.6637088134153526 1.0 1.0 220 Q92665,P04843,Q9Y285,P49589,P62841,P67812,P23381,P09132,Q9NR50,Q9H2W6,P60228,Q9UHB9,P61247,Q96EY7,P62854,Q9P015,P46199,P04844,Q9HA77,P61254,Q16540,P62081,P46778,Q5T160,Q13144,Q96RP9,P50914,Q9Y5M8,Q13084,P82933,P08865,P51571,P84098,P25398,P49458,P62917,Q96A35,P62899,Q9BW92,P62266,P62750,P46782,P29692,P61513,P55010,O76094,Q02543,P62753,P15880,Q7Z7H8,P43307,P46776,P27635,Q92552,P20042,Q9Y3D3 56
Cell death signalling via nrage nrif and nade 0.396205906124071 0.4324187655383319 0.6654370817315434 1.0 1.0 11 Q14344,Q92974,P63000,Q92888 4
Eukaryotic translation elongation 0.2628894973147282 0.4314469131662999 0.6661434449216439 1.0 1.0 78 P62841,P61247,P62854,P61254,P62081,P46778,P18621,P50914,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P29692,P61513,Q02543,P62753,P15880,P46776,P27635 23
Erks are inactivated 0.4173817248802894 0.4234937359966114 0.6719350678280525 1.0 1.0 8 Q14738,P27361,P30154,P30153,P28482,Q13164 6
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3202641942105626 0.4076571326375633 0.6835254132503235 1.0 1.0 23 P28340,P15927,P35244,Q9NR33,P27695 5
Metalloprotease dubs 0.4232836023881312 0.4056172172028023 0.6850238763162 1.0 1.0 7 O95630 1
Mitotic metaphase and anaphase 0.2530673310311961 0.4046953984609031 0.6857014250031324 1.0 1.0 145 Q14997,Q9UQE7,Q9UJX5,Q86XL3,Q8N1F7,P62191,Q8WUX9,Q96FJ2,P55735,Q13409,P04350,Q71F23,O00139,Q92530,Q96EA4,Q99986,Q9BZD4,Q9UNM6,O43242,Q15008,O95067,Q13257,Q14674,O43237,Q16763,P55036,Q9UJX4,Q9H1A4,O00231,Q96FZ7,P61289,Q9UJX2,P49721,O75122,P30622,P20700,P02545,Q96EE3,Q9BTX1 39
Signaling by flt3 fusion proteins 0.4366640492040239 0.3966702095607786 0.6916106710313192 1.0 1.0 5 Q14789,Q01082 2
Intra golgi traffic 0.387650954977581 0.3957704939856022 0.692274345665844 1.0 1.0 11 Q8TBA6,P83436,O15498,P33908,Q99747 5
Resolution of sister chromatid cohesion 0.2639546506498998 0.3950349587440576 0.6928170884014817 1.0 1.0 68 Q9BZD4,Q9UQE7,O95067,Q96FJ2,P55735,Q96EE3,P04350,Q13409,O00139 9
Asparagine n linked glycosylation 0.2627498823213158 0.3890403113128485 0.69724632659001 1.0 1.0 118 Q9UJW0,P24390,P04843,P48444,P49257,Q9NR45,P83436,P62191,Q96FJ2,Q14789,Q9Y5P6,P55735,Q13630,P33908,Q13409,P04350,Q2TAA5,P04844,P52907,P61923,P47755,O15498,O43237,Q9H6U8,Q99747,Q06210,Q13561,Q01082,O60763,Q9Y673,Q08379,Q9Y3B3,P49755,Q13813 34
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.271851316605722 0.3859369827082109 0.6995433402243842 1.0 1.0 49 Q14997,Q9UJX5,Q9UNM6,O00231,O43242,Q9UJX4,P62191,P61289,Q16763,P55036,Q9H1A4,P49721,Q9UJX2,Q92530 14
Hcmv infection 0.264427964534352 0.3830031329198566 0.7017174411478893 1.0 1.0 56 P12270,Q8N1F7,Q8WUX9,Q96FJ2,P55735,Q96EE3,Q13409,P04350,P83916,Q9BTX1 10
Tnfr2 non canonical nf kb pathway 0.2772783147017577 0.382796174335711 0.7018708982817996 1.0 1.0 43 Q14997,Q9UNM6,O00231,O15111,O43242,P62191,P61289,P55036,P49721,Q92530 10
Cd28 co stimulation 0.3987332040664378 0.3790447598912216 0.7046546258988702 1.0 1.0 9 P42345,P63000,Q16512 3
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.3973971417741562 0.373895197630672 0.7084822894941043 1.0 1.0 9 Q99873 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.2677237253196257 0.372736736717801 0.7093443916702324 1.0 1.0 51 Q14997,O00231,O95067,P61289,P55036,P04350,P49721 7
Interleukin 1 signaling 0.2684198884034824 0.3665848962425198 0.713928676108202 1.0 1.0 50 P09429,O15111,Q14997,P55036 4
Selenoamino acid metabolism 0.2597962549240433 0.3627430795785168 0.7167968155643336 1.0 1.0 91 P39023,P62841,P61247,P62854,P57772,P61254,P62081,P46778,P46777,P62851,P18621,P50914,P83731,P49591,P08865,P25398,P84098,P62917,P62266,P62899,P62750,P46782,P61513,Q02543,P62753,P15880,P46776,P27635,P00390,Q12904,P62913 31
Apoptosis 0.2599180011091141 0.3579951302620779 0.7203469578605559 1.0 1.0 93 P49354,Q9NR28,Q14997,O00231,P26583,P08670,P09429,O60313,Q96FJ2,Q96GX9,P51572,O00429,Q13813,P55036,P61289,P49721 16
Interleukin 1 family signaling 0.2644625909940585 0.3567800403814798 0.7212564796719958 1.0 1.0 53 P09429,O15111,Q14997,P55036 4
Trna processing 0.2605416858533214 0.3541154306014877 0.7232523784525116 1.0 1.0 63 Q2VPK5,O15091,O60294,Q969Y2,P12270,Q9Y606,Q8N1F7,Q52LJ0,P55735,Q96EE3,Q96FX7,Q9BTX1 12
Gamma carboxylation hypusine formation and arylsulfatase activation 0.3769970884463838 0.3517642736546714 0.7250150537333975 1.0 1.0 11 P38435,Q9BU89,O60725 3
Ret signaling 0.4079607902049904 0.3507890813571071 0.7257465891534132 1.0 1.0 7 P17252 1
Trna modification in the nucleus and cytosol 0.321532059540156 0.3487487210823996 0.7272779637336091 1.0 1.0 19 Q2VPK5,Q9Y606,Q96FX7,O60294 4
Transcriptional activation of mitochondrial biogenesis 0.3397397276924222 0.3465602626502587 0.7289217035683917 1.0 1.0 16 Q00059,P00367,Q15648,P06576,Q04837 5
Depolymerisation of the nuclear lamina 0.3819565958431811 0.3420431127375589 0.7323184475372173 1.0 1.0 10 P20700,P17252 2
Lagging strand synthesis 0.3176040983848929 0.3403862641326241 0.7335656614348824 1.0 1.0 20 P51530,P28340,P15927,P35244 4
Signaling by erbb2 0.3576258072888681 0.3379314527213639 0.7354148445822108 1.0 1.0 13 P17252,Q93034,Q16543 3
Apoptotic cleavage of cellular proteins 0.3113508790954259 0.3361620181350744 0.7367486930298439 1.0 1.0 22 P49354,P20700,P08670,P51572,P02545,Q13813 6
Apc c mediated degradation of cell cycle proteins 0.2587676748475797 0.3285728729741728 0.7424785548270323 1.0 1.0 58 Q14997,Q9UJX5,Q9UNM6,P24941,O00231,Q15008,O43242,P62191,Q9UJX4,P61289,Q16763,P55036,Q9H1A4,P49721,Q9UJX2,Q92530 16
Mitotic spindle checkpoint 0.2573295835711344 0.3153649023864645 0.7524846120263862 1.0 1.0 59 Q9BZD4,Q9H1A4,O75122,Q9UJX5,O00139,P30622,Q9UJX4,Q13257,Q96FJ2,O43237,P55735,Q16763,Q99661,Q96EE3,Q13409,Q71F23,Q9UJX2,Q96EA4 18
Signaling by ptk6 0.3674328552015505 0.3139380957448257 0.7535680557675577 1.0 1.0 11 Q14185,P63000,P24941 3
Nuclear events stimulated by alk signaling in cancer 0.3587220107220732 0.3089638488356848 0.757349026735348 1.0 1.0 12 P27361,P51608,P62753 3
Fc epsilon receptor fceri signaling 0.2557463061702739 0.3001178206484024 0.7640872864911572 1.0 1.0 57 Q14997,Q9UNM6,Q13177,P19174,O15111,O43242,O00231,P62191,P27361,P61289,P55036,Q16512,P49721,P63000,Q92530 15
Translesion synthesis by polk 0.3606077944491194 0.2879894692050561 0.7733547997022769 1.0 1.0 11 P15927,Q9UBZ9 2
Cell cycle checkpoints 0.2435641102482293 0.2844437347155683 0.7760703470205526 1.0 1.0 149 Q14997,Q9UJX5,P62191,Q96FJ2,P55735,P49959,Q13409,Q71F23,O00139,Q92993,Q92530,P25205,Q96EA4,Q9BZD4,Q9UNM6,O43242,Q15008,O95067,P15927,Q13257,Q16763,P55036,Q9UJX4,P51530,Q9H1A4,P24941,O00231,O14757,P16104,P35244,P61289,P33991,Q9UBD5,Q14566,Q9UJX2,P49721,Q92547,O75122,P30622,P33992,P54132,Q96EE3 42
Runx2 regulates genes involved in cell migration 0.3320394147506658 0.2839149356905969 0.7764755702641706 1.0 1.0 2 Q13951 1
Nonsense mediated decay nmd 0.2514642030301371 0.2811348629399435 0.7786069622661396 1.0 1.0 87 P62841,P61254,P62081,P46778,P50914,Q09161,P08865,P25398,P84098,P62917,Q9UPR3,P62899,P46782,Q9NPI6,P61513,Q02543,P62753,P15880,P27635 19
Processing of intronless pre mrnas 0.3309347846110729 0.2810880935313983 0.7786428331575115 1.0 1.0 15 Q86U42,Q09161 2
Ephrin signaling 0.4038950022556592 0.2792413458947306 0.7800596156339779 1.0 1.0 4 P63000,Q16512 2
Gap filling dna repair synthesis and ligation in gg ner 0.3074616669635664 0.2766308006714174 0.7820636117643285 1.0 1.0 19 P28340,Q9NR33,P15927,P35244 4
C type lectin receptors clrs 0.2526263588816513 0.2714698108059212 0.7860297156798102 1.0 1.0 57 Q09472,Q14997,Q9UNM6,Q13177,O00231,O15111,O43242,P62191,P61289,P55036,Q16512,P49721,P17252,Q92530 14
Tcr signaling 0.2565776840610048 0.2635907877558577 0.7920952578587372 1.0 1.0 50 Q14997,Q9UNM6,Q13177,P19174,O15111,O43242,O00231,P62191,P61289,P55036,Q16512,P49721,Q92530 13
Mrna capping 0.3392804152716295 0.2626295449940988 0.7928361255999388 1.0 1.0 13 Q09161 1
G2 m checkpoints 0.2501592584612757 0.2586304018095037 0.7959204238783189 1.0 1.0 89 Q14997,P24941,O00231,P15927,P33992,O95067,O14757,P16104,P35244,P61289,P55036,P51530,Q14566,Q92993,P49721,Q9UBD5 16
Transmission across chemical synapses 0.26043779551314 0.2574935018313508 0.7967978310228265 1.0 1.0 45 O14795,P21964,Q13555,P54646,P54619,P04350,P17252,P63000,Q12959 9
Beta oxidation of pristanoyl coa 0.3912167126952477 0.2555372261457065 0.7983081954099183 1.0 1.0 5 P51659,O15254 2
Ephb mediated forward signaling 0.3288903750961234 0.2518346658287653 0.8011688611992436 1.0 1.0 14 Q13464,P61160,Q92747,P59998,Q16512,P63000 6
Rna polymerase ii transcribes snrna genes 0.2711257138198152 0.247458398340769 0.8045534837475614 1.0 1.0 33 Q96HW7,Q09161,Q9NV88,Q9UL03,Q9NVM9,P55199,Q68E01,Q9NQG5 8
Dectin 1 mediated noncanonical nf kb signaling 0.2602154332926498 0.2468544129109892 0.8050208978358271 1.0 1.0 43 Q14997,Q9UNM6,O00231,O15111,O43242,P62191,P61289,P55036,P49721,Q92530 10
Runx2 regulates osteoblast differentiation 0.3834786506430224 0.2456890144925777 0.8059229767581799 1.0 1.0 6 P27361,Q9UBN7 2
Post translational modification synthesis of gpi anchored proteins 0.3905383881056511 0.2430938542969377 0.8079326920054906 1.0 1.0 4 Q92643 1
Rhobtb3 atpase cycle 0.386231251659214 0.2419073287312259 0.8088519712623101 1.0 1.0 5 P51151,Q15345 2
G alpha i signalling events 0.2769999179434779 0.2386943274036011 0.8113426157102053 1.0 1.0 28 P07602,P17252,Q86YR5,Q13555 4
Sumoylation of intracellular receptors 0.3527479091995121 0.2382057688374602 0.8117215030025933 1.0 1.0 3 O75925,Q8N2W9 2
Dna damage recognition in gg ner 0.2993896880589029 0.2377810385434942 0.8120509259815043 1.0 1.0 19 Q96EZ8,Q9UBW8 2
Transcription of the hiv genome 0.2711450803551489 0.2357526086039182 0.8136246444750319 1.0 1.0 31 P18074,P55199,Q14241,Q09161 4
Ion homeostasis 0.3391385978006787 0.2346815112234066 0.8144559389221206 1.0 1.0 12 P17252,P16615 2
Mapk family signaling cascades 0.2478970728075309 0.2336729634879905 0.8152388787206752 1.0 1.0 89 Q12959,Q16181,P49354,Q14997,O00231,P36507,Q13555,Q9HCE1,Q13813,P55036,P61289,Q16512,P17252,Q9NWH9,P63000,P49721,O60725 17
Formation of tc ner pre incision complex 0.2789095366362167 0.2281450946967408 0.8195334438636657 1.0 1.0 26 P18074,Q9HCS7,Q9UBW8 3
Triglyceride catabolism 0.3687301477709754 0.2266600068732339 0.8206881276299671 1.0 1.0 7 P17252 1
Triglyceride metabolism 0.3687301477709754 0.2266600068732339 0.8206881276299671 1.0 1.0 7 P17252 1
Transport of mature mrnas derived from intronless transcripts 0.2629451583471566 0.222488429062671 0.8239336798301737 1.0 1.0 37 P55735,Q9BTX1,Q09161 3
Late endosomal microautophagy 0.3477997739753274 0.221253807431853 0.8248948149675726 1.0 1.0 10 P08670 1
Runx3 regulates cdkn1a transcription 0.3114362496267482 0.220566751033028 0.8254297922782905 1.0 1.0 2 Q13485 1
Regulation of tp53 activity through phosphorylation 0.2644892438725966 0.2202708286965271 0.8256602375648217 1.0 1.0 35 P24941,P15927,O14757,P54646,P35244,P54619,P51530,Q92993 8
Signaling by fgfr 0.2893177656840076 0.2195798531488166 0.8261983833431858 1.0 1.0 22 P52597,P19174,Q09161,P35269,P27361,P30876,Q01085,P31483,P52272 9
Signaling by fgfr2 0.2893177656840076 0.2195798531488166 0.8261983833431858 1.0 1.0 22 P52597,P19174,Q09161,P35269,P27361,P30876,Q01085,P31483,P52272 9
Loss of function of mecp2 in rett syndrome 0.3661433665817226 0.219391063678451 0.8263454306269771 1.0 1.0 7 P17252 1
Dna damage bypass 0.2771675449239947 0.2184923822698496 0.8270454930198503 1.0 1.0 26 P28340,P15927,P35244,Q9UBZ9,Q9NR33,Q8TAT6 6
Cellular senescence 0.2528755742115428 0.2172194053852987 0.8280373624025477 1.0 1.0 48 Q9UJX5,Q00534,P24941,P20700,Q9UJX4,P16104,Q9HCE1,Q9H1A4,Q9UJX2,Q92993,P17096 11
G alpha 12 13 signalling events 0.3392093636719466 0.2127917128832098 0.8314894278816567 1.0 1.0 11 Q13464,Q14344,Q92974,Q92888,Q9H8V3 5
Programmed cell death 0.2490741450645207 0.2093054007938428 0.8342098359288197 1.0 1.0 105 P49354,Q9NR28,Q14997,O00231,Q14254,P26583,P08670,P09429,Q8WUX9,Q96FJ2,O60313,Q96GX9,P51572,O00429,Q13813,P55036,P61289,P49721 18
Dna damage telomere stress induced senescence 0.2930426726268738 0.208645111491411 0.834725291635706 1.0 1.0 19 P16104,P24941,Q92993,P17096 4
G alpha q signalling events 0.3235930070374887 0.2043032393519931 0.8381165387240768 1.0 1.0 13 P17252,Q8NCG7 2
Neurotransmitter receptors and postsynaptic signal transmission 0.258896435846256 0.2028550272533302 0.839248346427494 1.0 1.0 38 P54646,Q13555,P54619,P04350,P17252,P63000,Q12959 7
Fcgr3a mediated il10 synthesis 0.3575052127073734 0.1960024563856008 0.8446082433718045 1.0 1.0 7 P17252 1
Postmitotic nuclear pore complex npc reformation 0.2788941207999268 0.1940927966107761 0.8461032218497448 1.0 1.0 24 P55735,Q9BTX1 2
Costimulation by the cd28 family 0.3136554354942095 0.1937912867604197 0.8463393098393248 1.0 1.0 14 P42345,P63000,Q16512 3
Dual incision in tc ner 0.2602623514898626 0.1932216464726023 0.8467853867335084 1.0 1.0 35 P18074,Q09472,P28340,P15927,P35244,Q9HCS7,Q9NR33 7
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.2946818011686349 0.1926961360245166 0.8471969497478726 1.0 1.0 18 Q09472,P51532,Q86U86,Q969G3,P67870 5
Syndecan interactions 0.366218316505852 0.1912832685292656 0.8483036688429237 1.0 1.0 5 P17252 1
Rho gtpases activate paks 0.3263466551605219 0.1908206728668759 0.8486660916784692 1.0 1.0 12 P35580,Q13177,P35240,Q16512,P63000 5
Transcriptional regulation by ventx 0.3078959124191538 0.188466496330496 0.8505109769283801 1.0 1.0 15 Q9H1A4,Q9UJX5,Q9HCE1,Q9UJX4,Q9UJX2 5
Rhog gtpase cycle 0.2600024328318112 0.1841946198499408 0.8538607800098414 1.0 1.0 34 O15173,Q13576,Q86UP2,P34897,Q13017,Q86XL3,P49257 7
Rna polymerase i promoter escape 0.3021295250032244 0.1836489279982484 0.8542888768654546 1.0 1.0 16 P18074,P19447,P16104,Q9NYV6 4
Regulation of cholesterol biosynthesis by srebp srebf 0.270440693429354 0.1823990776716331 0.8552695495765439 1.0 1.0 26 Q15126,Q16850,Q13907,P37268 4
Signaling by robo receptors 0.2394503578623041 0.182369940495435 0.8552924142136116 1.0 1.0 139 Q14997,P62841,P61247,P62191,P62854,Q16512,Q92530,Q13177,Q9UNM6,O43242,Q15008,P61254,P62081,P46778,P55036,P18621,P50914,O00231,Q09161,P08865,P25398,P84098,P62917,P61289,O43347,P17252,P62266,P62899,P62750,P49721,P46782,O75122,P61513,Q02543,P62753,P15880,P46776,P27635,P63000 39
Cellular response to hypoxia 0.2504030003033085 0.1789350338735053 0.8579887136457969 1.0 1.0 44 Q09472,Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,Q9NWT6,P49721,Q92530 11
Fgfr2 alternative splicing 0.3047783481082172 0.1770432987911568 0.8594743792233688 1.0 1.0 15 P52597,Q09161,P35269,P30876,Q01085,P31483,P52272 7
Intracellular signaling by second messengers 0.2439282223245594 0.174282105525578 0.8616437617473853 1.0 1.0 94 Q14997,P49815,P62191,Q13555,Q92530,Q9UNM6,O15111,O43242,P42345,Q15008,P55036,Q9NWH9,Q12873,P19174,O00231,P48426,Q9HCE1,P61289,P17252,P49721,P67870,P14373,P27361,P63000,Q8WXI9 25
G1 s dna damage checkpoints 0.2503560097547735 0.1735741345103687 0.8622001610938788 1.0 1.0 42 Q14997,Q9UNM6,P24941,O00231,O43242,P62191,O14757,P61289,P55036,P49721,Q92530 11
Processing of capped intronless pre mrna 0.2947965766314428 0.173283672174375 0.8624284572615972 1.0 1.0 17 Q86U42,Q09161 2
Semaphorin interactions 0.2790384917288441 0.1708188057998628 0.8643662415174538 1.0 1.0 22 P35580,O94887,Q13464,Q13177,Q16512,P63000,Q9NWH9 7
Rho gtpases activate cit 0.3356719797336196 0.1700274101622909 0.8649885803061355 1.0 1.0 9 P35580,O43663,Q15334,P35579,P63000 5
Met promotes cell motility 0.3467655734172796 0.168868776738469 0.8658998590002276 1.0 1.0 7 Q9NWH9,P63000 2
Budding and maturation of hiv virion 0.3301588437815193 0.1681889571351587 0.8664346281258568 1.0 1.0 10 Q96PU5 1
Neddylation 0.2393712320767906 0.1670083587548044 0.8673634719628862 1.0 1.0 76 Q15345,Q14997,O00231,Q9H0A8,Q93034,Q96GG9,P61289,P55036,Q9BTE7,Q9UBW8,Q8NEZ5,P49721 12
Intrinsic pathway for apoptosis 0.2817629822169448 0.1662130196092689 0.8679893137999317 1.0 1.0 20 Q9NR28,Q96FJ2 2
Sema3a pak dependent axon repulsion 0.3442981399449323 0.1629453504790851 0.870561463444715 1.0 1.0 7 P63000,Q16512 2
Negative regulation of nmda receptor mediated neuronal transmission 0.3360339223309126 0.1597148738098908 0.873105683708093 1.0 1.0 8 Q12959,Q13557,Q13555,Q15334 4
Regulated necrosis 0.2777850832109754 0.1441011887264053 0.8854205660521623 1.0 1.0 19 Q14254,Q96FZ7,O75955,Q8WUX9,P09429,Q16543 6
Vegfr2 mediated vascular permeability 0.3163036440898369 0.1436657505687792 0.885764417661552 1.0 1.0 11 P42345,P63000,Q13177,Q16512 4
Constitutive signaling by ligand responsive egfr cancer variants 0.344267759715826 0.1436182018041294 0.8858019667066308 1.0 1.0 5 Q16543 1
Signaling by egfr in cancer 0.344267759715826 0.1436182018041294 0.8858019667066308 1.0 1.0 5 Q16543 1
Constitutive signaling by egfrviii 0.344267759715826 0.1436182018041294 0.8858019667066308 1.0 1.0 5 Q16543 1
Mtor signalling 0.2985004491065197 0.1422637145958094 0.886871706518437 1.0 1.0 14 P54619,P54646,P62753 3
Insulin receptor signalling cascade 0.3398887988678331 0.1393921132142917 0.8891403042625172 1.0 1.0 6 P27361 1
Irf3 mediated induction of type i ifn 0.3369207772795299 0.133397537970313 0.8938789924227339 1.0 1.0 6 P13010,P78527,Q9UHD2,P49959,Q9UJV9 5
Synthesis of pips at the early endosome membrane 0.3368961020398873 0.1333483786457596 0.8939178685753402 1.0 1.0 6 Q99570,Q08AM6 2
Response of mtb to phagocytosis 0.3016945928052135 0.1333440946865429 0.8939212564259116 1.0 1.0 13 P27361,Q9H267,P23246,P14373 4
Infection with mycobacterium tuberculosis 0.3016945928052135 0.1333440946865429 0.8939212564259116 1.0 1.0 13 P27361,Q9H267,P23246,P14373 4
Regulation of pten stability and activity 0.2436594947614879 0.1310365759121241 0.8957463734552074 1.0 1.0 43 Q14997,Q9UNM6,O00231,P67870,O43242,P62191,P14373,P61289,P55036,P49721,Q92530 11
Signaling by fgfr4 0.3285411528553853 0.1279024219085034 0.898226194384691 1.0 1.0 7 P27361 1
Signaling by fgfr3 0.3285411528553853 0.1279024219085034 0.898226194384691 1.0 1.0 7 P27361 1
Signaling by fgfr1 0.3285411528553853 0.1279024219085034 0.898226194384691 1.0 1.0 7 P27361 1
Sensing of dna double strand breaks 0.3346515787088439 0.125395638713521 0.9002103406664244 1.0 1.0 5 P49959,Q92993 2
Pi5p regulates tp53 acetylation 0.3344153541541055 0.1249684531340022 0.9005485252659464 1.0 1.0 5 Q09472 1
Cdt1 association with the cdc6 orc origin complex 0.2440448910981677 0.1231938769400102 0.9019535741300104 1.0 1.0 40 Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,Q9UBD5,P49721,Q92530 10
Separation of sister chromatids 0.2414121751132228 0.1221810873818135 0.90275560430964 1.0 1.0 111 Q14997,Q9UQE7,Q9UJX5,P62191,Q96FJ2,P55735,Q13409,P04350,Q71F23,O00139,Q92530,Q96EA4,Q9BZD4,Q9UNM6,O43242,Q15008,Q13257,Q14674,Q16763,P55036,Q9UJX4,Q9H1A4,O00231,P61289,Q9UJX2,P49721,O75122,P30622,Q96EE3 29
Cytosolic trna aminoacylation 0.2649676830226847 0.1185063203187226 0.905666487496501 1.0 1.0 23 P54136,P49591,Q9Y285,P41250,P49589,P23381,Q12904 7
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.2899042266310131 0.1159545517014216 0.9076885612316504 1.0 1.0 14 Q99873,Q09472,Q9HCE1 3
Snrnp assembly 0.2411105713988063 0.1136241719390093 0.9095357250059448 1.0 1.0 42 Q09161,P12270,Q8N1F7,O14744,P55735,Q96EE3,Q9BTX1 7
Fceri mediated nf kb activation 0.2396707206673632 0.1128595749775059 0.9101418859952104 1.0 1.0 46 O15111,Q14997,P55036 3
Rna polymerase i transcription 0.2548187820246729 0.1119032410928589 0.9109001267268168 1.0 1.0 27 P18074,Q12873,Q9NYV6,P16104,Q13185,P27361,P19447,Q8WXI9 8
Glutamate and glutamine metabolism 0.318090283469961 0.1073353910066212 0.9145229087477692 1.0 1.0 7 P00367,Q96C36 2
Cell cycle 0.2104303864032934 0.1049208457506984 0.9164386177456 1.0 1.0 313 P00374,P28340,O43242,O95067,Q9UJX4,Q9Y2S7,Q13561,Q14566,Q9UJX2,Q86XI2,P30622,P27361,P02545,Q8WVB6,Q9BTX1,Q14997,Q86XL3,Q8WUX9,P55735,P42695,Q13409,Q99996,O95235,P25205,Q9BZD4,Q00534,Q14674,Q16763,P55036,P51530,O60763,P33991,Q9UBD5,P49721,P67870,P04818,Q92547,Q96EE3,O15504,P04183,P62191,Q96FJ2,P49959,Q8WXH0,P04350,Q71F23,Q92993,Q92530,Q96EA4,Q99986,Q9UNM6,P15927,Q15008,Q13257,Q9H1A4,P24941,P17252,Q08379,O75330,Q09472,Q9UQE7,Q9UJX5,P23258,O00139,Q9BRT9,Q9NR33,O00231,P12270,O14757,P16104,P35244,P61289,Q9UIS9,O75122,P20700,P33992,P54132,Q9BSJ2,Q8N1F7 79
Condensation of prophase chromosomes 0.2964202651022088 0.10411383262999 0.9170790136656616 1.0 1.0 12 P16104,Q86XI2 2
Rora activates gene expression 0.3205773748898018 0.1016452944344779 0.9190382258498682 1.0 1.0 5 Q09472 1
Diseases of mismatch repair mmr 0.3207499187689179 0.1012126938351652 0.9193816202420686 1.0 1.0 4 P20585 1
Downregulation of erbb2 signaling 0.3128526293327923 0.0978294133828551 0.9220677509025464 1.0 1.0 7 Q93034 1
Formation of the early elongation complex 0.2724817267459818 0.094690108005616 0.924560975340555 1.0 1.0 17 P18074,Q09161 2
Regulation of glucokinase by glucokinase regulatory protein 0.2490777802277642 0.0918226449628226 0.9268389519876912 1.0 1.0 28 P55735,P12270,Q96EE3,Q9BTX1 4
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.284892137586845 0.0877560164570934 0.9300705966178868 1.0 1.0 13 Q8WXI9,Q12873,P16104,Q13185 4
Gene silencing by rna 0.2353595140768989 0.0855136586056253 0.9318530372493246 1.0 1.0 46 P12270,P16104,P55735,Q96EE3,Q9Y2W6,Q9BTX1 6
Rac3 gtpase cycle 0.2419209275364532 0.0830593999487353 0.9338043083984476 1.0 1.0 34 O15173,Q13177,Q13017,P49257,Q9Y2A7,O15498,Q9UQB8,Q16512,Q68EM7,Q01968 10
Gastrin creb signalling pathway via pkc and mapk 0.3052720551988033 0.0794638758663469 0.9366636636040284 1.0 1.0 6 P17252 1
Nucleotide salvage 0.2946136964617297 0.0777527333727515 0.9380247458680628 1.0 1.0 9 Q9P2T1,P55263 2
Darpp 32 events 0.2920474581071228 0.0777397842164232 0.9380350466215288 1.0 1.0 10 P17252 1
Dna damage reversal 0.2990737974305271 0.0734947891980899 0.9414123904804914 1.0 1.0 4 Q9H1I8,Q8N3C0,Q6P6C2 3
Metabolism of polyamines 0.2356518007755824 0.0692155078707298 0.9448180792159632 1.0 1.0 39 Q14997,Q9UNM6,O00231,O43242,P62191,P19623,P61289,P55036,P49721,Q92530 10
Nuclear events kinase and transcription factor activation 0.2703426389496062 0.0642419886175683 0.9487775443426048 1.0 1.0 14 Q09472,P50570 2
Sumoylation of chromatin organization proteins 0.2352412713338293 0.0626599397094621 0.950037298155515 1.0 1.0 38 Q12873,P12270,P55735,Q96EE3,Q9BTX1 5
Irs mediated signalling 0.2844338213325297 0.0588022763667877 0.9531095953216472 1.0 1.0 4 Q99570,Q06124,P31751 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.2845188284518759 0.0559759525115533 0.9553609642336274 1.0 1.0 5 Q99570,O14654,Q06124,P31751 4
Recognition of dna damage by pcna containing replication complex 0.2517816801414998 0.0552198214100894 0.9559633378252212 1.0 1.0 20 P28340,Q9NR33,P15927,P35244 4
Neuronal system 0.2256370245837584 0.0540356285574042 0.956906778211716 1.0 1.0 55 Q9Y2J2,O14795,Q14254,P21964,Q13555,P54646,P54619,P04350,P17252,P63000,Q12959 11
Negative regulation of fgfr1 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5
Negative regulation of fgfr4 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5
Negative regulation of fgfr2 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5
Negative regulation of fgfr3 signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5
Spry regulation of fgf signaling 0.2846038863976166 0.0537301816977507 0.9571501360091303 1.0 1.0 6 P22681,P27361,P30153,P28482,Q06124 5
Downstream signaling events of b cell receptor bcr 0.2293751219258552 0.0499875819060378 0.9601322841542548 1.0 1.0 46 O15111,Q14997,P55036 3
Translesion synthesis by polh 0.2672123635564776 0.04831240639014 0.9614672672309617 1.0 1.0 13 P15927,Q8TAT6 2
Hiv life cycle 0.2266407456473269 0.0447870836172544 0.964277020542817 1.0 1.0 84 P18074,Q09161,Q14241,Q96PU5,Q8WUX9,P18615,P55735,Q96EE3,P55199,P17096,Q9BTX1 11
Formation of tubulin folding intermediates by cct tric 0.262432594367899 0.0391321581201664 0.9687850221250918 1.0 1.0 13 P49368,Q9BVA1,Q9BUF5,P50991,Q99832,P17987,Q13885,P68371,P50990,P04350,P40227,P78371 12
Sumoylation of sumoylation proteins 0.2339430412350507 0.0389897143938711 0.9688985891041426 1.0 1.0 30 P55735,P12270,Q9BTX1,Q96EE3 4
Signaling by notch1 pest domain mutants in cancer 0.2655688622754458 0.0360393285917254 0.9712509996290172 1.0 1.0 11 Q09472,Q06330,Q9UBN7,O75376,P63208,Q92793,Q92769,Q92542,Q13616,Q13547 10
Notch hlh transcription pathway 0.26533054142985 0.0351865940699098 0.9719309519950856 1.0 1.0 8 Q06330,Q9UBN7,O75376,Q92793,Q92769,Q04721,Q13547 7
Traf6 mediated irf7 activation 0.2651658045436415 0.0346825408026546 0.972332882972646 1.0 1.0 7 Q09472,Q9C037,Q12933,Q14258 4
Rac2 gtpase cycle 0.2309749768201215 0.0344935087407608 0.9724836185442782 1.0 1.0 35 O15173,Q13505 2
Ca dependent events 0.2656136882790748 0.034493286458576 0.9724837957943246 1.0 1.0 9 P17252 1
Bbsome mediated cargo targeting to cilium 0.2618834080717589 0.0331836141490099 0.9735281649414482 1.0 1.0 6 P49368,P50991,P17987,P50990,P78371 5
Regulation of tp53 activity 0.2223969819583501 0.0317710823316983 0.9746546079461113 1.0 1.0 58 Q09472,Q12873,Q92547,P24941,P67870,P15927,P42345,P48426,P54646,O14757,P35244,O14744,P54132,P54619,P51530,Q92993,Q8WXI9 17
Folding of actin by cct tric 0.2620400837571012 0.0317557908558672 0.9746668026253338 1.0 1.0 8 P49368,P50991,Q99832,P17987,P50990,P40227,P78371 7
Regulation of expression of slits and robos 0.2316231664520089 0.0316907144040486 0.9747187000010864 1.0 1.0 124 Q14997,P62841,P61247,P62191,P62854,Q92530,Q9UNM6,O43242,Q15008,P61254,P62081,P46778,P55036,P18621,P50914,O00231,Q09161,P08865,P25398,P84098,P62917,P61289,O43347,P62266,P62899,P62750,P49721,P46782,P61513,Q02543,P62753,P15880,P46776,P27635 34
Signaling by erbb2 in cancer 0.2487344436510397 0.0294411260342475 0.9765127731763232 1.0 1.0 5 Q16543 1
Signaling by erbb2 ecd mutants 0.2487344436510397 0.0294411260342475 0.9765127731763232 1.0 1.0 5 Q16543 1
Negative regulation of the pi3k akt network 0.2521526062475964 0.0287076607088995 0.977097746525 1.0 1.0 15 P63000,P27361,P48426,Q9NWH9 4
Estrogen dependent nuclear events downstream of esr membrane signaling 0.2318494173886989 0.0278803058747574 0.9777576159727106 1.0 1.0 4 P27361,P28482,P31751 3
Degradation of gli1 by the proteasome 0.2252213705880999 0.0250031042149009 0.9800524875783578 1.0 1.0 42 Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,P49721,P17252,Q92530 10
Negative regulation of mapk pathway 0.2574993298073603 0.0245902454422323 0.9803817999579711 1.0 1.0 11 P36507 1
Cytokine signaling in immune system 0.2086683602950439 0.0242761154816462 0.9806323646003364 1.0 1.0 186 P14174,Q14997,O15111,P08670,P09429,P09601,O15344,P55735,Q96EE3,P55036,Q13126,P26038,Q00169,P49721,Q9BTX1 15
Translation of sars cov 2 structural proteins 0.2433591354339924 0.0228411977214195 0.9817769455578892 1.0 1.0 18 P04844,P78362,Q99873,Q10472 4
Protein protein interactions at synapses 0.2497838508831805 0.0221004495668545 0.9823678278620812 1.0 1.0 14 Q9Y2J2,Q15334,Q14254,O75955,Q12959 5
Rmts methylate histone arginines 0.238723231558749 0.0205222105493968 0.9836267943501112 1.0 1.0 22 O14744,Q99873,Q969G3,P16104 4
Pten regulation 0.2224971794625215 0.0193113852421122 0.984592701513164 1.0 1.0 67 Q14997,Q12873,Q9UNM6,O00231,P67870,O43242,P42345,P62191,P14373,P27361,Q9HCE1,P61289,P55036,P49721,Q92530,Q8WXI9 16
Traf3 dependent irf activation pathway 0.2365465873484706 0.0182723175597645 0.9854216111663764 1.0 1.0 6 Q09472,Q9C037,Q14258 3
Aquaporin mediated transport 0.245959829721712 0.0175554045710274 0.9859935331851972 1.0 1.0 8 P17252 1
Degradation of axin 0.2264025361907124 0.0175058198590895 0.986033089982489 1.0 1.0 37 Q14997,Q9UNM6,O00231,O43242,P62191,P61289,P55036,P49721,Q92530 9
Mitochondrial trna aminoacylation 0.2409521970819756 0.0172101742019714 0.9862689455525876 1.0 1.0 18 Q9HA77 1
Transcriptional regulation by mecp2 0.2381506992723469 0.0165081135649231 0.9868290292819746 1.0 1.0 20 P17252,Q9HCE1,Q9NWH9,Q13555 4
Fanconi anemia pathway 0.2461043841595118 0.0145708001818474 0.988374594859324 1.0 1.0 9 P15927 1
Translocation of slc2a4 glut4 to the plasma membrane 0.225584991072566 0.0139304877238149 0.988885438401047 1.0 1.0 37 Q9Y4I1,P54646,Q12846,P54619,Q8IYI6,Q9UPT5,P04350,P35579,P63000 9
Thrombin signalling through proteinase activated receptors pars 0.2305622009569376 0.0113343265162199 0.9909567094933605 1.0 1.0 7 P29992,P62873,P27361,Q14344,P28482,Q9UBI6 6
Signaling by notch 0.2199807218310375 0.0094686321087773 0.9924452375156838 1.0 1.0 63 Q09472,P67809,Q9UNM6,O00231,O43242,P62191,P16104,Q9UBN7,Q9HCE1,P61289,P55036,P49721,P16615,Q92530 14
Sars cov 2 infection 0.2286103901683352 0.0055551520896669 0.9955676527115837 1.0 1.0 26 P78362,Q99873,Q8WUX9 3
Sumoylation of ubiquitinylation proteins 0.2244499939306571 0.0019355002589282 0.9984556951901736 1.0 1.0 31 P12270,P55735,Q96EE3,Q9BTX1,Q8N1F7 5
Gap junction trafficking and regulation 0.2379964523887378 0.0012115629075325 0.999033312898136 1.0 1.0 12 P04350 1
Suppression of phagosomal maturation 0.1961722488038293 0.0006820042936855 0.9994558393458512 1.0 1.0 7 Q9H267,Q9UI12,P51149,P20339,P52294,Q14974 6